locus-tag	class	description
CHD23_RS00040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CHD23_RS00045	COG2271	Major facilitator Superfamily
CHD23_RS00055	COG0561	phosphatase activity
CHD23_RS00075	COG2198	Histidine kinase
CHD23_RS00075	COG2205	protein histidine kinase activity
CHD23_RS00075	COG0784	Response regulator, receiver
CHD23_RS00080	COG1879	ABC-type sugar transport system periplasmic component
CHD23_RS00085	COG0745	RESPONSE REGULATOR receiver
CHD23_RS00090	COG3005	denitrification pathway
CHD23_RS00105	COG1858	cytochrome C peroxidase
CHD23_RS00115	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD23_RS00120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD23_RS00125	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD23_RS00135	COG1138	Cytochrome C-type biogenesis protein
CHD23_RS00140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHD23_RS00145	COG4235	cytochrome complex assembly
CHD23_RS00145	COG3088	subunit of a heme lyase
CHD23_RS00150	COG0823	Involved in the tonB-independent uptake of proteins
CHD23_RS00155	COG5645	(Lipo)protein
CHD23_RS00170	COG0071	Belongs to the small heat shock protein (HSP20) family
CHD23_RS00185	COG2149	membrane
CHD23_RS00195	COG0641	radical SAM
CHD23_RS00205	COG2814	Major facilitator Superfamily
CHD23_RS00235	COG0028	Belongs to the TPP enzyme family
CHD23_RS00240	COG0440	acetolactate synthase activity
CHD23_RS00245	COG1349	DNA-binding transcription factor activity
CHD23_RS00255	COG0738	Major facilitator superfamily
CHD23_RS00295	COG2723	6-phospho-beta-galactosidase activity
CHD23_RS00315	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD23_RS00315	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS00320	COG3715	PTS system
CHD23_RS00325	COG3716	PTS system mannose fructose sorbose family IID component
CHD23_RS00340	COG5464	transposase or invertase
CHD23_RS00350	COG1285	pathogenesis
CHD23_RS00380	COG1335	isochorismatase
CHD23_RS00395	COG2211	Major facilitator Superfamily
CHD23_RS00400	COG1501	Belongs to the glycosyl hydrolase 31 family
CHD23_RS00405	COG2982	Protein involved in outer membrane biogenesis
CHD23_RS00410	COG2233	PERMEase
CHD23_RS00415	COG0786	glutamate:sodium symporter activity
CHD23_RS00420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHD23_RS00425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHD23_RS00430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHD23_RS00450	COG2860	membrane
CHD23_RS00465	COG1561	YicC-like family, N-terminal region
CHD23_RS00495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHD23_RS00525	COG1519	Transferase
CHD23_RS00530	COG0859	PFAM glycosyl transferase family 9
CHD23_RS00535	COG0438	transferase activity, transferring glycosyl groups
CHD23_RS00610	COG1216	Glycosyl transferase, family 2
CHD23_RS00615	COG2861	carbohydrate metabolic process
CHD23_RS00620	COG4942	peptidase
CHD23_RS00630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHD23_RS00635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CHD23_RS00655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CHD23_RS00665	COG2186	Transcriptional regulator
CHD23_RS00690	COG3722	fumarate hydratase activity
CHD23_RS00700	COG2213	PTS system mannitol-specific
CHD23_RS00700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS00705	COG0625	glutathione transferase activity
CHD23_RS00715	COG3276	selenocysteine insertion sequence binding
CHD23_RS00720	COG1454	alcohol dehydrogenase
CHD23_RS00725	COG1940	carbohydrate kinase activity
CHD23_RS00730	COG1012	belongs to the aldehyde dehydrogenase family
CHD23_RS00740	COG2211	Major facilitator Superfamily
CHD23_RS00750	COG0235	Class ii aldolase
CHD23_RS00755	COG3623	hexulose-6-phosphate isomerase
CHD23_RS00760	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CHD23_RS00765	COG1070	Carbohydrate kinase
CHD23_RS00770	COG2271	Major facilitator Superfamily
CHD23_RS00780	COG2731	YhcH YjgK YiaL family protein
CHD23_RS00795	COG1414	Transcriptional regulator
CHD23_RS00800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD23_RS00805	COG3977	Valine--pyruvate aminotransferase
CHD23_RS00810	COG0366	Alpha amylase catalytic
CHD23_RS00815	COG2992	FlgJ-related protein
CHD23_RS00820	COG1609	Transcriptional regulator
CHD23_RS00820	COG2207	Transcriptional regulator
CHD23_RS00835	COG1070	Carbohydrate kinase
CHD23_RS00845	COG3274	enterobacterial common antigen metabolic process
CHD23_RS00875	COG1278	Cold shock
CHD23_RS00880	COG2944	sequence-specific DNA binding
CHD23_RS00900	COG2885	chlorophyll binding
CHD23_RS00905	COG0243	molybdopterin cofactor binding
CHD23_RS00910	COG0456	acetyltransferase
CHD23_RS00915	COG2818	Glycosylase
CHD23_RS00920	COG5571	outer membrane autotransporter
CHD23_RS00945	COG0747	negative chemotaxis
CHD23_RS00950	COG0601	transmembrane transport
CHD23_RS00955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHD23_RS00960	COG0444	Belongs to the ABC transporter superfamily
CHD23_RS00965	COG4608	Belongs to the ABC transporter superfamily
CHD23_RS00970	COG0814	amino acid
CHD23_RS01010	COG1215	transferase activity, transferring glycosyl groups
CHD23_RS01015	COG1215	transferase activity, transferring glycosyl groups
CHD23_RS01035	COG2200	EAL domain
CHD23_RS01035	COG2199	diguanylate cyclase activity
CHD23_RS01050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD23_RS01055	COG2200	EAL domain
CHD23_RS01060	COG2982	Protein involved in outer membrane biogenesis
CHD23_RS01065	COG0477	Major facilitator Superfamily
CHD23_RS01070	COG1295	ribonuclease BN
CHD23_RS01075	COG0583	DNA-binding transcription factor activity
CHD23_RS01085	COG2197	response regulator
CHD23_RS01105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHD23_RS01110	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CHD23_RS01145	COG0306	phosphate transporter
CHD23_RS01150	COG2081	HI0933 family
CHD23_RS01155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD23_RS01160	COG0842	Transport permease protein
CHD23_RS01160	COG1129	ABC transporter
CHD23_RS01165	COG0842	Transport permease protein
CHD23_RS01175	COG2091	lysine biosynthetic process via aminoadipic acid
CHD23_RS01180	COG0628	permease
CHD23_RS01195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CHD23_RS01215	COG3714	YhhN family
CHD23_RS01225	COG3776	membrane
CHD23_RS01230	COG0742	ribosomal rna small subunit methyltransferase
CHD23_RS01235	COG0552	protein localization to endoplasmic reticulum
CHD23_RS01240	COG2884	Cell division ATP-binding protein ftsE
CHD23_RS01245	COG2177	Part of the ABC transporter FtsEX involved in
CHD23_RS01310	COG0584	glycerophosphoryl diester phosphodiesterase
CHD23_RS01320	COG0405	Gamma-glutamyltransferase
CHD23_RS01335	COG3157	Type VI secretion system effector, Hcp
CHD23_RS01340	COG0673	inositol 2-dehydrogenase activity
CHD23_RS01345	COG1741	Belongs to the pirin family
CHD23_RS01350	COG1609	Transcriptional regulator
CHD23_RS01355	COG3265	gluconokinase activity
CHD23_RS01360	COG2610	gluconate transmembrane transporter activity
CHD23_RS01375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHD23_RS01395	COG0058	SHG alpha-glucan phosphorylase activity
CHD23_RS01400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHD23_RS01425	COG1640	4-alpha-glucanotransferase
CHD23_RS01430	COG2610	gluconate transmembrane transporter activity
CHD23_RS01465	COG1918	ferrous iron import across plasma membrane
CHD23_RS01475	COG2183	response to ionizing radiation
CHD23_RS01480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHD23_RS01500	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CHD23_RS01510	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHD23_RS01515	COG1011	Hydrolase
CHD23_RS01525	COG0494	nUDIX hydrolase
CHD23_RS01530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHD23_RS01535	COG4972	Pilus assembly protein
CHD23_RS01540	COG3166	PFAM Fimbrial assembly family protein
CHD23_RS01555	COG4796	Type ii and iii secretion system protein
CHD23_RS01575	COG3266	domain, Protein
CHD23_RS01580	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CHD23_RS01585	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHD23_RS01625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHD23_RS01660	COG1289	transmembrane transporter activity
CHD23_RS01675	COG1765	OsmC-like protein
CHD23_RS01680	COG3954	Phosphoribulokinase
CHD23_RS01690	COG0429	hydrolase of the alpha beta-hydrolase fold
CHD23_RS01700	COG0488	(ABC) transporter
CHD23_RS01715	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CHD23_RS01720	COG1047	Peptidyl-prolyl cis-trans
CHD23_RS01730	COG0545	Peptidyl-prolyl cis-trans isomerase
CHD23_RS01735	COG2964	Protein conserved in bacteria
CHD23_RS01800	COG0051	transcription antitermination factor activity, RNA binding
CHD23_RS01825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHD23_RS01905	COG0201	protein transport
CHD23_RS01935	COG0203	ribosomal protein L17
CHD23_RS01945	COG0789	Transcriptional regulator
CHD23_RS01950	COG3036	rescue of stalled ribosome
CHD23_RS01980	COG0758	DNA mediated transformation
CHD23_RS01990	COG0551	DNA topoisomerase type I activity
CHD23_RS02010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CHD23_RS02055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHD23_RS02060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD23_RS02065	COG1309	transcriptional regulator
CHD23_RS02080	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CHD23_RS02105	COG4145	pantothenate transmembrane transporter activity
CHD23_RS02110	COG3924	membrane
CHD23_RS02115	COG0439	Biotin carboxylase
CHD23_RS02120	COG0511	ligase activity, forming carbon-carbon bonds
CHD23_RS02135	COG0604	alcohol dehydrogenase
CHD23_RS02140	COG2200	EAL domain
CHD23_RS02140	COG2199	diguanylate cyclase activity
CHD23_RS02155	COG1077	Cell shape determining protein MreB Mrl
CHD23_RS02160	COG1792	Involved in formation and maintenance of cell shape
CHD23_RS02165	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CHD23_RS02180	COG3164	Protein of unknown function
CHD23_RS02185	COG0312	modulator of DNA gyrase
CHD23_RS02195	COG0583	DNA-binding transcription factor activity
CHD23_RS02215	COG2732	(Barnase) inhibitor
CHD23_RS02245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHD23_RS02250	COG3105	Protein conserved in bacteria
CHD23_RS02255	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CHD23_RS02270	COG0625	glutathione transferase activity
CHD23_RS02275	COG2969	positive regulation of protein catabolic process
CHD23_RS02305	COG2731	YhcH YjgK YiaL family protein
CHD23_RS02310	COG0402	S-adenosylhomocysteine deaminase activity
CHD23_RS02315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CHD23_RS02325	COG0493	'glutamate synthase
CHD23_RS02330	COG0070	glutamate synthase
CHD23_RS02330	COG0069	glutamate synthase activity
CHD23_RS02330	COG0067	glutamate synthase
CHD23_RS02340	COG1242	4 iron, 4 sulfur cluster binding
CHD23_RS02345	COG0784	Response regulator, receiver
CHD23_RS02345	COG2198	Histidine kinase
CHD23_RS02345	COG5002	protein histidine kinase activity
CHD23_RS02350	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CHD23_RS02360	COG0515	serine threonine protein kinase
CHD23_RS02365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS02390	COG1137	ATPase activity
CHD23_RS02395	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CHD23_RS02400	COG3117	lipopolysaccharide transmembrane transporter activity
CHD23_RS02405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CHD23_RS02415	COG0530	calcium, potassium:sodium antiporter activity
CHD23_RS02420	COG1127	ABC transporter
CHD23_RS02425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CHD23_RS02430	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CHD23_RS02435	COG2854	intermembrane phospholipid transfer
CHD23_RS02440	COG3113	response to antibiotic
CHD23_RS02445	COG5007	Belongs to the BolA IbaG family
CHD23_RS02455	COG3423	Transcriptional regulator
CHD23_RS02460	COG0142	geranyltranstransferase activity
CHD23_RS02475	COG0697	spore germination
CHD23_RS02485	COG2027	D-alanyl-D-alanine carboxypeptidase
CHD23_RS02495	COG1534	Rna-binding protein
CHD23_RS02515	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHD23_RS02525	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHD23_RS02585	COG0513	Belongs to the DEAD box helicase family
CHD23_RS02590	COG0814	amino acid
CHD23_RS02595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHD23_RS02600	COG0826	peptidase U32
CHD23_RS02605	COG0826	peptidase U32
CHD23_RS02610	COG3154	lipid carrier protein
CHD23_RS02615	COG3153	acetyltransferase
CHD23_RS02630	COG0693	protein deglycase activity
CHD23_RS02635	COG0702	epimerase
CHD23_RS02640	COG2823	Periplasmic or secreted lipoprotein
CHD23_RS02660	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHD23_RS02670	COG2222	sugar isomerase
CHD23_RS02675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CHD23_RS02685	COG1349	DNA-binding transcription factor activity
CHD23_RS02705	COG0583	DNA-binding transcription factor activity
CHD23_RS02725	COG1882	Formate acetyltransferase
CHD23_RS02730	COG1760	l-serine dehydratase
CHD23_RS02735	COG0814	amino acid
CHD23_RS02750	COG1741	Belongs to the pirin family
CHD23_RS02755	COG0583	DNA-binding transcription factor activity
CHD23_RS02760	COG3152	Membrane
CHD23_RS02765	COG0435	Glutathione S-transferase
CHD23_RS02770	COG2259	Doxx family
CHD23_RS02780	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CHD23_RS02785	COG4575	ribosome binding
CHD23_RS02790	COG1422	Protein of unknown function (DUF1090)
CHD23_RS02800	COG0586	Pfam SNARE associated Golgi protein
CHD23_RS02805	COG2186	Transcriptional regulator
CHD23_RS02810	COG2271	Major facilitator Superfamily
CHD23_RS02820	COG2721	sulfolactate sulfo-lyase activity
CHD23_RS02835	COG0673	inositol 2-dehydrogenase activity
CHD23_RS02845	COG1451	nucleotide metabolic process
CHD23_RS02855	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHD23_RS02855	COG1902	pentaerythritol trinitrate reductase activity
CHD23_RS02870	COG0840	transmembrane signaling receptor activity
CHD23_RS02875	COG0840	transmembrane signaling receptor activity
CHD23_RS02880	COG1695	Transcriptional regulator
CHD23_RS02885	COG2375	cellular response to nickel ion
CHD23_RS02920	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHD23_RS02940	COG0471	metal ion transport
CHD23_RS02945	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD23_RS02950	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD23_RS02965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CHD23_RS02980	COG4991	sh3 domain protein
CHD23_RS02990	COG3025	triphosphatase activity
CHD23_RS03050	COG3384	dioxygenase
CHD23_RS03055	COG0754	glutathionylspermidine amidase activity
CHD23_RS03075	COG0494	nUDIX hydrolase
CHD23_RS03080	COG3151	Protein conserved in bacteria
CHD23_RS03085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CHD23_RS03090	COG3150	esterase
CHD23_RS03100	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CHD23_RS03105	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHD23_RS03110	COG0642	Histidine kinase
CHD23_RS03120	COG3111	PFAM Bacterial OB fold (BOF) protein
CHD23_RS03145	COG3157	Type VI secretion system effector, Hcp
CHD23_RS03175	COG0471	metal ion transport
CHD23_RS03185	COG1979	alcohol dehydrogenase
CHD23_RS03190	COG2207	Transcriptional regulator
CHD23_RS03215	COG0848	biopolymer transport protein
CHD23_RS03220	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS03245	COG0840	transmembrane signaling receptor activity
CHD23_RS03260	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CHD23_RS03265	COG0437	4 iron, 4 sulfur cluster binding
CHD23_RS03270	COG5557	Pfam Polysulphide reductase, NrfD
CHD23_RS03275	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CHD23_RS03280	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CHD23_RS03285	COG1773	rubredoxin
CHD23_RS03295	COG0298	carbon dioxide binding
CHD23_RS03300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHD23_RS03310	COG0625	glutathione transferase activity
CHD23_RS03315	COG0754	glutathionylspermidine amidase activity
CHD23_RS03325	COG2211	Major facilitator Superfamily
CHD23_RS03345	COG0246	Mannitol dehydrogenase
CHD23_RS03360	COG2271	Major facilitator Superfamily
CHD23_RS03375	COG1012	belongs to the aldehyde dehydrogenase family
CHD23_RS03380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHD23_RS03390	COG0531	amino acid
CHD23_RS03425	COG2030	dehydratase
CHD23_RS03430	COG0427	acetyl-CoA hydrolase
CHD23_RS03500	COG3501	Rhs element vgr protein
CHD23_RS03530	COG1811	Na channel or pump
CHD23_RS03540	COG1982	Orn Lys Arg decarboxylase major
CHD23_RS03575	COG3171	Protein conserved in bacteria
CHD23_RS03585	COG0252	asparaginase activity
CHD23_RS03590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHD23_RS03605	COG0762	integral membrane protein
CHD23_RS03610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHD23_RS03615	COG2805	Type II/IV secretion system protein
CHD23_RS03640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHD23_RS03645	COG2356	endonuclease I
CHD23_RS03655	COG2814	Major facilitator Superfamily
CHD23_RS03680	COG1166	arginine decarboxylase activity
CHD23_RS03690	COG0501	Belongs to the peptidase M48B family
CHD23_RS03695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CHD23_RS03700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHD23_RS03705	COG2211	Major facilitator Superfamily
CHD23_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS03720	COG3959	Transketolase, thiamine diphosphate binding domain
CHD23_RS03725	COG3958	Transketolase
CHD23_RS03730	COG1122	ATPase activity
CHD23_RS03735	COG1122	ATPase activity
CHD23_RS03770	COG0191	fructose-bisphosphate aldolase activity
CHD23_RS03775	COG0668	transmembrane transport
CHD23_RS03785	COG2968	Membrane
CHD23_RS03790	COG0583	DNA-binding transcription factor activity
CHD23_RS03795	COG0427	acetyl-CoA hydrolase
CHD23_RS03800	COG1024	Enoyl-CoA hydratase
CHD23_RS03805	COG1703	isobutyryl-CoA mutase activity
CHD23_RS03810	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHD23_RS03810	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHD23_RS03830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHD23_RS03835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHD23_RS03860	COG0006	proline dipeptidase activity
CHD23_RS03865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHD23_RS03870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHD23_RS03890	COG2723	6-phospho-beta-galactosidase activity
CHD23_RS03900	COG1272	protein, Hemolysin III
CHD23_RS03960	COG4942	peptidase
CHD23_RS03990	COG3468	outer membrane autotransporter barrel domain protein
CHD23_RS04005	COG0814	amino acid
CHD23_RS04020	COG0183	Belongs to the thiolase family
CHD23_RS04035	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS04045	COG1794	racemase activity, acting on amino acids and derivatives
CHD23_RS04050	COG0583	DNA-binding transcription factor activity
CHD23_RS04060	COG1609	Transcriptional regulator
CHD23_RS04085	COG0477	Major facilitator Superfamily
CHD23_RS04090	COG0667	Aldo Keto reductase
CHD23_RS04100	COG0861	Integral membrane protein TerC family
CHD23_RS04135	COG2165	general secretion pathway protein
CHD23_RS04140	COG4795	General secretion pathway protein
CHD23_RS04150	COG4967	type IV pilus modification protein PilV
CHD23_RS04155	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CHD23_RS04165	COG1074	ATP-dependent DNA helicase activity
CHD23_RS04170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHD23_RS04175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHD23_RS04175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CHD23_RS04180	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHD23_RS04195	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CHD23_RS04200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHD23_RS04205	COG2962	Rard protein
CHD23_RS04210	COG2166	iron-sulfur cluster assembly
CHD23_RS04215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHD23_RS04225	COG0583	DNA-binding transcription factor activity
CHD23_RS04230	COG2363	Small membrane protein
CHD23_RS04240	COG1349	DNA-binding transcription factor activity
CHD23_RS04260	COG0738	Major facilitator superfamily
CHD23_RS04265	COG0235	Class ii aldolase
CHD23_RS04270	COG1454	alcohol dehydrogenase
CHD23_RS04280	COG1611	Belongs to the LOG family
CHD23_RS04300	COG3098	single-species biofilm formation
CHD23_RS04310	COG0716	FMN binding
CHD23_RS04320	COG2205	protein histidine kinase activity
CHD23_RS04320	COG3850	Histidine kinase
CHD23_RS04320	COG3437	response regulator, receiver
CHD23_RS04320	COG4999	Histidine kinase
CHD23_RS04330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHD23_RS04335	COG3956	TIGRFAM MazG family protein
CHD23_RS04370	COG0602	queuosine metabolic process
CHD23_RS04375	COG0720	synthase
CHD23_RS04410	COG1203	CRISPR-associated helicase, Cas3
CHD23_RS04435	COG1857	crispr-associated protein
CHD23_RS04450	COG1518	maintenance of DNA repeat elements
CHD23_RS04455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHD23_RS04460	COG2234	aminopeptidase activity
CHD23_RS04530	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CHD23_RS04535	COG0163	prenyltransferase activity
CHD23_RS04545	COG1349	DNA-binding transcription factor activity
CHD23_RS04550	COG2084	Dehydrogenase
CHD23_RS04560	COG0235	Class ii aldolase
CHD23_RS04565	COG3622	Belongs to the hyi family
CHD23_RS04570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHD23_RS04575	COG2610	gluconate transmembrane transporter activity
CHD23_RS04585	COG0477	Major facilitator Superfamily
CHD23_RS04625	COG4974	Belongs to the 'phage' integrase family
CHD23_RS04700	COG2207	Transcriptional regulator
CHD23_RS04790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHD23_RS04810	COG0741	lytic transglycosylase activity
CHD23_RS04875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHD23_RS04880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHD23_RS04885	COG1121	(ABC) transporter
CHD23_RS04905	COG0309	Hydrogenase expression formation protein (HypE)
CHD23_RS04910	COG0409	Hydrogenase expression formation protein
CHD23_RS04915	COG0298	carbon dioxide binding
CHD23_RS04920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHD23_RS04940	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD23_RS04945	COG0651	ATP synthesis coupled electron transport
CHD23_RS04950	COG0650	Formate hydrogenlyase subunit 4
CHD23_RS04955	COG3261	NADH dehydrogenase
CHD23_RS04955	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CHD23_RS04960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHD23_RS04965	COG3260	NADH ubiquinone oxidoreductase 20
CHD23_RS04975	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CHD23_RS04980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD23_RS04985	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CHD23_RS05005	COG0517	IMP dehydrogenase activity
CHD23_RS05005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHD23_RS05010	COG1349	DNA-binding transcription factor activity
CHD23_RS05015	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS05030	COG3732	PTS system glucitol sorbitol-specific
CHD23_RS05035	COG3730	PTS system glucitol sorbitol-specific
CHD23_RS05040	COG2951	lytic endotransglycosylase activity
CHD23_RS05045	COG1546	Belongs to the CinA family
CHD23_RS05070	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CHD23_RS05105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHD23_RS05110	COG1238	metal cluster binding
CHD23_RS05125	COG2814	Major facilitator Superfamily
CHD23_RS05130	COG1566	PFAM secretion protein HlyD family protein
CHD23_RS05135	COG1846	Transcriptional regulator
CHD23_RS05140	COG2814	Major facilitator Superfamily
CHD23_RS05175	COG1780	Probably involved in ribonucleotide reductase function
CHD23_RS05185	COG4575	ribosome binding
CHD23_RS05215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHD23_RS05220	COG0640	Transcriptional regulator
CHD23_RS05225	COG0401	homolog of Blt101
CHD23_RS05235	COG1652	LysM domain
CHD23_RS05240	COG1802	Transcriptional regulator
CHD23_RS05245	COG1113	amino acid transport
CHD23_RS05250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHD23_RS05255	COG1012	belongs to the aldehyde dehydrogenase family
CHD23_RS05260	COG0579	oxidoreductase
CHD23_RS05295	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CHD23_RS05310	COG2990	Protein conserved in bacteria
CHD23_RS05330	COG2819	hydrolase of the alpha beta superfamily
CHD23_RS05355	COG3023	N-Acetylmuramoyl-L-alanine amidase
CHD23_RS05395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD23_RS05420	COG2867	negative regulation of translational initiation
CHD23_RS05435	COG0497	DNA recombination
CHD23_RS05455	COG4536	flavin adenine dinucleotide binding
CHD23_RS05460	COG4137	Cytochrome C assembly protein
CHD23_RS05470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHD23_RS05495	COG2199	diguanylate cyclase activity
CHD23_RS05510	COG1605	Chorismate mutase
CHD23_RS05510	COG0287	Prephenate dehydrogenase
CHD23_RS05520	COG1605	Chorismate mutase
CHD23_RS05520	COG0077	Prephenate dehydratase
CHD23_RS05530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHD23_RS05535	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHD23_RS05545	COG1496	oxidoreductase activity
CHD23_RS05550	COG0542	response to heat
CHD23_RS05590	COG0477	Major facilitator Superfamily
CHD23_RS05595	COG5544	Lipoprotein
CHD23_RS05600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHD23_RS05610	COG3148	PFAM DTW domain containing protein
CHD23_RS05615	COG3118	belongs to the thioredoxin family
CHD23_RS05620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHD23_RS05635	COG0513	Belongs to the DEAD box helicase family
CHD23_RS05645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CHD23_RS05670	COG3086	response to oxidative stress
CHD23_RS05720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD23_RS05725	COG1737	Transcriptional regulator
CHD23_RS05730	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CHD23_RS05735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD23_RS05735	COG1263	PTS System
CHD23_RS05740	COG0560	Phosphoserine phosphatase
CHD23_RS05765	COG2205	protein histidine kinase activity
CHD23_RS05770	COG3170	Tfp pilus assembly protein FimV
CHD23_RS05775	COG2204	response regulator
CHD23_RS05780	COG0347	Belongs to the P(II) protein family
CHD23_RS05785	COG3104	oligopeptide transport
CHD23_RS05795	COG0531	amino acid
CHD23_RS05800	COG3710	Transcriptional regulator
CHD23_RS05805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHD23_RS05805	COG1017	nitric oxide dioxygenase activity
CHD23_RS05815	COG2814	Major facilitator Superfamily
CHD23_RS05820	COG3711	transcriptional antiterminator
CHD23_RS05830	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CHD23_RS05870	COG0822	iron-sulfur transferase activity
CHD23_RS05890	COG0633	Ferredoxin
CHD23_RS05895	COG2975	iron-sulfur cluster assembly
CHD23_RS05915	COG2897	thiosulfate sulfurtransferase activity
CHD23_RS05920	COG2373	Large extracellular alpha-helical protein
CHD23_RS05925	COG4953	penicillin-binding protein 1C
CHD23_RS05930	COG0243	molybdopterin cofactor binding
CHD23_RS05935	COG0437	4 iron, 4 sulfur cluster binding
CHD23_RS05980	COG2976	Protein conserved in bacteria
CHD23_RS05995	COG1645	bacterial-type flagellum-dependent swarming motility
CHD23_RS06015	COG0517	IMP dehydrogenase activity
CHD23_RS06015	COG0516	GMP reductase activity
CHD23_RS06045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHD23_RS06055	COG3133	Outer membrane lipoprotein
CHD23_RS06070	COG2200	EAL domain
CHD23_RS06085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHD23_RS06100	COG2233	PERMEase
CHD23_RS06110	COG1393	Belongs to the ArsC family
CHD23_RS06120	COG0628	permease
CHD23_RS06125	COG3835	regulator
CHD23_RS06130	COG2610	gluconate transmembrane transporter activity
CHD23_RS06135	COG1929	Belongs to the glycerate kinase type-1 family
CHD23_RS06140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHD23_RS06145	COG2716	regulation of RNA biosynthetic process
CHD23_RS06150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHD23_RS06155	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CHD23_RS06165	COG2321	neutral zinc metallopeptidase
CHD23_RS06185	COG1393	Belongs to the ArsC family
CHD23_RS06195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHD23_RS06200	COG3850	Histidine kinase
CHD23_RS06210	COG0493	'glutamate synthase
CHD23_RS06210	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD23_RS06225	COG5342	invasion associated locus B
CHD23_RS06235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CHD23_RS06255	COG3119	arylsulfatase activity
CHD23_RS06375	COG2837	iron assimilation
CHD23_RS06395	COG4208	sulfate ABC transporter
CHD23_RS06440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS06465	COG3530	Putative quorum-sensing-regulated virulence factor
CHD23_RS06470	COG0385	Bile acid
CHD23_RS06475	COG0583	DNA-binding transcription factor activity
CHD23_RS06550	COG3209	COG3209 Rhs family protein
CHD23_RS06610	COG3415	Transposase
CHD23_RS06615	COG3415	Transposase
CHD23_RS06635	COG2199	diguanylate cyclase activity
CHD23_RS06635	COG2200	EAL domain
CHD23_RS06640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHD23_RS06655	COG0667	Aldo Keto reductase
CHD23_RS06660	COG3961	Belongs to the TPP enzyme family
CHD23_RS06675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD23_RS06680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD23_RS06685	COG0006	proline dipeptidase activity
CHD23_RS06690	COG1363	Peptidase, m42
CHD23_RS06695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHD23_RS06695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS06695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS06700	COG2207	Transcriptional regulator
CHD23_RS06705	COG0436	Aminotransferase
CHD23_RS06715	COG1560	Kdo2-lipid A biosynthetic process
CHD23_RS06755	COG2116	formate transmembrane transporter activity
CHD23_RS06765	COG2067	long-chain fatty acid transport protein
CHD23_RS06770	COG3691	Protein conserved in bacteria
CHD23_RS06785	COG2062	phosphohistidine phosphatase, SixA
CHD23_RS06810	COG0730	response to heat
CHD23_RS06815	COG3101	peptidyl-lysine hydroxylation
CHD23_RS06830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHD23_RS06845	COG3423	Transcriptional regulator
CHD23_RS06870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHD23_RS06880	COG0586	Pfam SNARE associated Golgi protein
CHD23_RS06890	COG0285	dihydrofolate synthase activity
CHD23_RS06895	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CHD23_RS06905	COG1286	toxin biosynthetic process
CHD23_RS06910	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHD23_RS06915	COG3829	transcription factor binding
CHD23_RS06925	COG0531	amino acid
CHD23_RS06930	COG3457	Alanine racemase
CHD23_RS06935	COG0833	amino acid
CHD23_RS06975	COG1090	epimerase
CHD23_RS06985	COG0625	glutathione transferase activity
CHD23_RS06990	COG0625	glutathione transferase activity
CHD23_RS06995	COG0622	Phosphoesterase
CHD23_RS07005	COG1609	Transcriptional regulator
CHD23_RS07015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS07025	COG3037	sugar-specific permease SgaT UlaA
CHD23_RS07030	COG3959	Transketolase, thiamine diphosphate binding domain
CHD23_RS07035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHD23_RS07040	COG1288	antiporter activity
CHD23_RS07065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHD23_RS07070	COG0490	domain, Protein
CHD23_RS07070	COG0471	metal ion transport
CHD23_RS07080	COG0436	Aminotransferase
CHD23_RS07090	COG0583	DNA-binding transcription factor activity
CHD23_RS07140	COG0839	Belongs to the complex I subunit 6 family
CHD23_RS07150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHD23_RS07155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHD23_RS07165	COG0835	chemotaxis
CHD23_RS07165	COG0784	Response regulator, receiver
CHD23_RS07175	COG2153	protein acetylation
CHD23_RS07180	COG4575	ribosome binding
CHD23_RS07185	COG1169	isochorismate synthase
CHD23_RS07280	COG0247	lactate metabolic process
CHD23_RS07290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHD23_RS07295	COG2271	Major facilitator Superfamily
CHD23_RS07300	COG0584	glycerophosphoryl diester phosphodiesterase
CHD23_RS07305	COG0583	DNA-binding transcription factor activity
CHD23_RS07310	COG2814	Major facilitator Superfamily
CHD23_RS07315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHD23_RS07350	COG0642	Histidine kinase
CHD23_RS07350	COG2198	Histidine kinase
CHD23_RS07375	COG4615	Cyclic peptide transporter
CHD23_RS07380	COG0659	secondary active sulfate transmembrane transporter activity
CHD23_RS07390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD23_RS07390	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD23_RS07395	COG3062	negative regulation of establishment of protein localization
CHD23_RS07405	COG0437	4 iron, 4 sulfur cluster binding
CHD23_RS07410	COG0348	domain, Protein
CHD23_RS07415	COG3043	anaerobic respiration
CHD23_RS07420	COG3005	denitrification pathway
CHD23_RS07430	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD23_RS07435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD23_RS07440	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD23_RS07450	COG1138	Cytochrome C-type biogenesis protein
CHD23_RS07455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHD23_RS07460	COG4235	cytochrome complex assembly
CHD23_RS07460	COG3088	subunit of a heme lyase
CHD23_RS07465	COG2197	response regulator
CHD23_RS07555	COG1061	Type III restriction enzyme res subunit
CHD23_RS07565	COG2814	Major facilitator Superfamily
CHD23_RS07580	COG4172	Belongs to the ABC transporter superfamily
CHD23_RS07585	COG4239	(ABC) transporter, permease
CHD23_RS07590	COG4174	ABC transporter (Permease)
CHD23_RS07595	COG4166	transmembrane transport
CHD23_RS07600	COG2200	EAL domain
CHD23_RS07605	COG0791	NLP P60 protein
CHD23_RS07615	COG0671	phosphoesterase, PA-phosphatase related
CHD23_RS07620	COG0523	cobalamin synthesis protein
CHD23_RS07625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHD23_RS07630	COG3005	denitrification pathway
CHD23_RS07640	COG3381	protein complex oligomerization
CHD23_RS07670	COG1105	Belongs to the carbohydrate kinase PfkB family
CHD23_RS07675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD23_RS07675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD23_RS07675	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CHD23_RS07680	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CHD23_RS07685	COG2855	membrane
CHD23_RS07690	COG0583	DNA-binding transcription factor activity
CHD23_RS07695	COG0833	amino acid
CHD23_RS07705	COG4771	TonB-dependent receptor
CHD23_RS07730	COG2311	Membrane
CHD23_RS07770	COG0493	'glutamate synthase
CHD23_RS07780	COG2949	membrane
CHD23_RS07790	COG1346	cytolysis
CHD23_RS07805	COG2271	Major facilitator Superfamily
CHD23_RS07820	COG0625	glutathione transferase activity
CHD23_RS07825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHD23_RS07830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHD23_RS07840	COG1538	Outer membrane efflux protein
CHD23_RS07845	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS07850	COG0586	Pfam SNARE associated Golgi protein
CHD23_RS07865	COG1686	Belongs to the peptidase S11 family
CHD23_RS07870	COG0277	FAD linked oxidase domain protein
CHD23_RS07880	COG1732	Glycine betaine
CHD23_RS07885	COG1174	glycine betaine transport
CHD23_RS07890	COG1125	glycine betaine transport
CHD23_RS07895	COG1174	glycine betaine transport
CHD23_RS07910	COG3275	phosphorelay sensor kinase activity
CHD23_RS07920	COG4807	Protein conserved in bacteria
CHD23_RS07925	COG4808	Protein conserved in bacteria
CHD23_RS07945	COG3539	Fimbrial protein
CHD23_RS07950	COG3121	Chaperone
CHD23_RS07965	COG5455	response to cobalt ion
CHD23_RS07980	COG2188	Transcriptional regulator
CHD23_RS07985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD23_RS07990	COG1397	ADP-ribosylglycohydrolase
CHD23_RS07995	COG2211	Major facilitator Superfamily
CHD23_RS08000	COG1830	Aldolase
CHD23_RS08020	COG0826	peptidase U32
CHD23_RS08025	COG0745	RESPONSE REGULATOR receiver
CHD23_RS08030	COG2205	protein histidine kinase activity
CHD23_RS08060	COG0443	Heat shock 70 kDa protein
CHD23_RS08070	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CHD23_RS08075	COG3447	MASE1 domain protein
CHD23_RS08075	COG5001	Diguanylate cyclase
CHD23_RS08075	COG5002	protein histidine kinase activity
CHD23_RS08090	COG2982	Protein involved in outer membrane biogenesis
CHD23_RS08095	COG1253	flavin adenine dinucleotide binding
CHD23_RS08120	COG0463	Glycosyl transferase, family 2
CHD23_RS08125	COG1045	serine acetyltransferase
CHD23_RS08130	COG0438	transferase activity, transferring glycosyl groups
CHD23_RS08140	COG1216	Glycosyl transferase, family 2
CHD23_RS08145	COG0110	maltose O-acetyltransferase activity
CHD23_RS08150	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CHD23_RS08155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHD23_RS08165	COG0297	glycogen (starch) synthase activity
CHD23_RS08180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHD23_RS08185	COG2244	polysaccharide biosynthetic process
CHD23_RS08190	COG2327	Polysaccharide pyruvyl transferase
CHD23_RS08225	COG2244	polysaccharide biosynthetic process
CHD23_RS08230	COG0562	UDP-galactopyranose mutase
CHD23_RS08335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHD23_RS08340	COG0583	DNA-binding transcription factor activity
CHD23_RS08350	COG0531	amino acid
CHD23_RS08355	COG2925	Exonuclease
CHD23_RS08385	COG1289	transmembrane transporter activity
CHD23_RS08445	COG0582	viral genome integration into host DNA
CHD23_RS08460	COG0534	Mate efflux family protein
CHD23_RS08470	COG0582	viral genome integration into host DNA
CHD23_RS08505	COG2814	Major facilitator Superfamily
CHD23_RS08510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHD23_RS08525	COG0473	3-isopropylmalate dehydrogenase activity
CHD23_RS08525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CHD23_RS08535	COG0583	DNA-binding transcription factor activity
CHD23_RS08660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHD23_RS08680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CHD23_RS08690	COG1418	mRNA catabolic process
CHD23_RS08695	COG0270	DNA (cytosine-5-)-methyltransferase activity
CHD23_RS08700	COG3727	T/G mismatch-specific endonuclease activity
CHD23_RS08705	COG0697	spore germination
CHD23_RS08710	COG2354	Protein conserved in bacteria
CHD23_RS08715	COG5475	Uncharacterized small protein (DUF2158)
CHD23_RS08820	COG0425	Belongs to the sulfur carrier protein TusA family
CHD23_RS08875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD23_RS08885	COG0765	amino acid transport
CHD23_RS08890	COG1126	abc transporter atp-binding protein
CHD23_RS08895	COG2197	response regulator
CHD23_RS08905	COG2197	response regulator
CHD23_RS08960	COG3012	SEC-C Motif Domain Protein
CHD23_RS08960	COG3318	Belongs to the UPF0149 family
CHD23_RS08965	COG0814	amino acid
CHD23_RS08975	COG1528	Iron-storage protein
CHD23_RS08995	COG1528	Iron-storage protein
CHD23_RS09100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CHD23_RS09115	COG3102	Protein conserved in bacteria
CHD23_RS09130	COG0500	methyltransferase
CHD23_RS09140	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CHD23_RS09145	COG1801	Protein of unknown function DUF72
CHD23_RS09185	COG2135	peptidase activity
CHD23_RS09190	COG1335	isochorismatase
CHD23_RS09200	COG0494	nUDIX hydrolase
CHD23_RS09205	COG0217	transcriptional regulatory protein
CHD23_RS09225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHD23_RS09235	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CHD23_RS09240	COG0739	heme binding
CHD23_RS09250	COG1560	Kdo2-lipid A biosynthetic process
CHD23_RS09260	COG1737	Transcriptional regulator
CHD23_RS09270	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHD23_RS09275	COG0129	dihydroxy-acid dehydratase activity
CHD23_RS09280	COG0800	Aldolase
CHD23_RS09290	COG3141	response to X-ray
CHD23_RS09300	COG2979	Protein of unknown function (DUF533)
CHD23_RS09305	COG1770	oligopeptidase
CHD23_RS09310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHD23_RS09315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHD23_RS09325	COG2372	response to copper ion
CHD23_RS09330	COG1276	copper resistance
CHD23_RS09365	COG3723	Recombinational DNA repair protein, rece pathway
CHD23_RS09370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHD23_RS09415	COG1484	DNA-dependent DNA replication
CHD23_RS09475	COG3772	lysozyme
CHD23_RS09570	COG1388	LysM domain
CHD23_RS09570	COG0741	lytic transglycosylase activity
CHD23_RS09610	COG5301	cellulose 1,4-beta-cellobiosidase activity
CHD23_RS09645	COG0582	viral genome integration into host DNA
CHD23_RS09655	COG3093	addiction module antidote protein HigA
CHD23_RS09770	COG3188	usher protein
CHD23_RS09815	COG3008	intermembrane lipid transfer
CHD23_RS09820	COG2995	paraquat-inducible protein a
CHD23_RS09825	COG1956	GAF domain-containing protein
CHD23_RS09845	COG2814	Major facilitator Superfamily
CHD23_RS09850	COG1414	Transcriptional regulator
CHD23_RS09880	COG0768	penicillin binding
CHD23_RS09885	COG2226	methyltransferase
CHD23_RS09905	COG3716	PTS system mannose fructose sorbose family IID component
CHD23_RS09910	COG3715	PTS system
CHD23_RS09915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD23_RS09915	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS09925	COG1253	flavin adenine dinucleotide binding
CHD23_RS09930	COG2200	EAL domain
CHD23_RS09935	COG1760	l-serine dehydratase
CHD23_RS09955	COG0251	oxidation-reduction process
CHD23_RS09960	COG1199	ATP-dependent helicase activity
CHD23_RS09970	COG3065	identical protein binding
CHD23_RS09985	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CHD23_RS09995	COG2894	cell division
CHD23_RS10010	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHD23_RS10075	COG2719	SpoVR family
CHD23_RS10095	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHD23_RS10120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHD23_RS10130	COG1294	oxidase, subunit
CHD23_RS10135	COG1271	oxidase subunit
CHD23_RS10140	COG1773	rubredoxin
CHD23_RS10145	COG1999	signal sequence binding
CHD23_RS10150	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CHD23_RS10155	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CHD23_RS10180	COG3119	arylsulfatase activity
CHD23_RS10185	COG1349	DNA-binding transcription factor activity
CHD23_RS10190	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD23_RS10195	COG3715	PTS system
CHD23_RS10200	COG3716	PTS system mannose fructose sorbose family IID component
CHD23_RS10205	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS10215	COG0641	radical SAM
CHD23_RS10220	COG3119	arylsulfatase activity
CHD23_RS10240	COG0582	viral genome integration into host DNA
CHD23_RS10245	COG0012	GTP binding
CHD23_RS10260	COG0659	secondary active sulfate transmembrane transporter activity
CHD23_RS10310	COG0387	Pfam Sodium calcium exchanger
CHD23_RS10315	COG4572	Cation transport regulator
CHD23_RS10320	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CHD23_RS10325	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CHD23_RS10330	COG4932	domain protein
CHD23_RS10335	COG2197	response regulator
CHD23_RS10340	COG3850	Histidine kinase
CHD23_RS10350	COG2223	nitrite transmembrane transporter activity
CHD23_RS10355	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CHD23_RS10360	COG1140	nitrate reductase beta subunit
CHD23_RS10365	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CHD23_RS10370	COG2181	nitrate reductase activity
CHD23_RS10395	COG0788	formyltetrahydrofolate deformylase activity
CHD23_RS10405	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHD23_RS10410	COG0745	RESPONSE REGULATOR receiver
CHD23_RS10415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHD23_RS10430	COG1012	belongs to the aldehyde dehydrogenase family
CHD23_RS10430	COG1454	alcohol dehydrogenase
CHD23_RS10435	COG2095	MarC family integral membrane protein
CHD23_RS10470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHD23_RS10485	COG2350	Protein conserved in bacteria
CHD23_RS10510	COG0727	PFAM Uncharacterised protein family (UPF0153)
CHD23_RS10515	COG3047	cAMP biosynthetic process
CHD23_RS10520	COG3546	catalase activity
CHD23_RS10525	COG3685	Protein conserved in bacteria
CHD23_RS10530	COG3685	Protein conserved in bacteria
CHD23_RS10535	COG3729	General stress protein
CHD23_RS10575	COG0009	L-threonylcarbamoyladenylate synthase
CHD23_RS10590	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS10595	COG0616	signal peptide processing
CHD23_RS10645	COG0671	phosphoesterase, PA-phosphatase related
CHD23_RS10655	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CHD23_RS10660	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CHD23_RS10680	COG1349	DNA-binding transcription factor activity
CHD23_RS10690	COG5001	Diguanylate cyclase
CHD23_RS10765	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CHD23_RS10770	COG1842	Phage shock protein A
CHD23_RS10780	COG1983	PspC domain protein
CHD23_RS10790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHD23_RS10795	COG3106	COG3106 Predicted ATPase
CHD23_RS10815	COG4948	Mandelate Racemase Muconate Lactonizing
CHD23_RS10820	COG2866	Carboxypeptidase
CHD23_RS10825	COG4166	transmembrane transport
CHD23_RS10835	COG0667	Aldo Keto reductase
CHD23_RS10850	COG2814	Major facilitator Superfamily
CHD23_RS10870	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS10890	COG0656	L-ascorbic acid biosynthetic process
CHD23_RS10895	COG3842	ATPase activity
CHD23_RS10910	COG0395	ABC-type sugar transport system, permease component
CHD23_RS10915	COG4209	transmembrane transport
CHD23_RS10920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD23_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS10930	COG1309	transcriptional regulator
CHD23_RS10965	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CHD23_RS10985	COG0668	transmembrane transport
CHD23_RS10990	COG3182	Iron-regulated membrane protein
CHD23_RS11010	COG2840	Smr protein MutS2
CHD23_RS11020	COG0840	transmembrane signaling receptor activity
CHD23_RS11035	COG0513	Belongs to the DEAD box helicase family
CHD23_RS11055	COG2076	Multidrug Resistance protein
CHD23_RS11070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHD23_RS11070	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHD23_RS11070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHD23_RS11070	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHD23_RS11080	COG3042	response to heat
CHD23_RS11085	COG3187	Heat shock protein
CHD23_RS11090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHD23_RS11095	COG2911	Protein conserved in bacteria
CHD23_RS11105	COG3784	Protein of unknown function (DUF1318)
CHD23_RS11120	COG1643	Atp-dependent helicase
CHD23_RS11125	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CHD23_RS11130	COG3038	cytochrome b561
CHD23_RS11135	COG0500	methyltransferase
CHD23_RS11140	COG0765	amino acid transport
CHD23_RS11145	COG1126	abc transporter atp-binding protein
CHD23_RS11150	COG0765	amino acid transport
CHD23_RS11155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD23_RS11205	COG0840	transmembrane signaling receptor activity
CHD23_RS11210	COG0583	DNA-binding transcription factor activity
CHD23_RS11215	COG5383	Protein conserved in bacteria
CHD23_RS11220	COG2272	Belongs to the type-B carboxylesterase lipase family
CHD23_RS11230	COG2353	YceI-like domain
CHD23_RS11235	COG1304	FMN binding
CHD23_RS11245	COG1349	DNA-binding transcription factor activity
CHD23_RS11330	COG1473	amidohydrolase
CHD23_RS11335	COG2860	membrane
CHD23_RS11345	COG1363	Peptidase, m42
CHD23_RS11350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHD23_RS11355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CHD23_RS11360	COG1275	C4-dicarboxylate transporter malic acid transport protein
CHD23_RS11365	COG0500	methyltransferase
CHD23_RS11375	COG3135	benzoate transporter
CHD23_RS11380	COG1396	sequence-specific DNA binding
CHD23_RS11385	COG0826	peptidase U32
CHD23_RS11400	COG1294	oxidase, subunit
CHD23_RS11405	COG1271	oxidase subunit
CHD23_RS11425	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CHD23_RS11430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHD23_RS11470	COG3238	Protein conserved in bacteria
CHD23_RS11480	COG2130	NADP-dependent
CHD23_RS11485	COG1802	Transcriptional regulator
CHD23_RS11490	COG4772	TonB-dependent receptor
CHD23_RS11530	COG2181	nitrate reductase activity
CHD23_RS11535	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CHD23_RS11540	COG1140	nitrate reductase beta subunit
CHD23_RS11545	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CHD23_RS11585	COG0243	molybdopterin cofactor binding
CHD23_RS11585	COG3383	formate dehydrogenase (NAD+) activity
CHD23_RS11590	COG0243	molybdopterin cofactor binding
CHD23_RS11590	COG3383	formate dehydrogenase (NAD+) activity
CHD23_RS11595	COG0437	4 iron, 4 sulfur cluster binding
CHD23_RS11600	COG2864	formate dehydrogenase
CHD23_RS11605	COG1064	alcohol dehydrogenase
CHD23_RS11625	COG1764	response to oxidative stress
CHD23_RS11640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHD23_RS11655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CHD23_RS11660	COG1757	Na H antiporter
CHD23_RS11665	COG1609	Transcriptional regulator
CHD23_RS11795	COG2814	Major facilitator Superfamily
CHD23_RS11800	COG4221	oxidoreductase activity
CHD23_RS11810	COG2207	Transcriptional regulator
CHD23_RS11820	COG1280	lysine exporter protein (LysE YggA)
CHD23_RS11825	COG0583	DNA-binding transcription factor activity
CHD23_RS11830	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHD23_RS11855	COG2271	Major facilitator Superfamily
CHD23_RS11860	COG1063	alcohol dehydrogenase
CHD23_RS11865	COG2186	Transcriptional regulator
CHD23_RS11875	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CHD23_RS11880	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CHD23_RS11905	COG1773	rubredoxin
CHD23_RS11935	COG3781	membrane
CHD23_RS11955	COG1012	belongs to the aldehyde dehydrogenase family
CHD23_RS11960	COG0583	DNA-binding transcription factor activity
CHD23_RS11990	COG4566	intracellular signal transduction
CHD23_RS12005	COG2814	Major facilitator Superfamily
CHD23_RS12020	COG3111	PFAM Bacterial OB fold (BOF) protein
CHD23_RS12025	COG1546	Belongs to the CinA family
CHD23_RS12030	COG3729	General stress protein
CHD23_RS12045	COG4221	oxidoreductase activity
CHD23_RS12050	COG1802	Transcriptional regulator
CHD23_RS12060	COG0246	Mannitol dehydrogenase
CHD23_RS12065	COG0477	Major facilitator Superfamily
CHD23_RS12070	COG1063	alcohol dehydrogenase
CHD23_RS12090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHD23_RS12105	COG0243	molybdopterin cofactor binding
CHD23_RS12110	COG0243	molybdopterin cofactor binding
CHD23_RS12115	COG0437	4 iron, 4 sulfur cluster binding
CHD23_RS12120	COG3302	dmso reductase anchor subunit
CHD23_RS12155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CHD23_RS12160	COG1940	carbohydrate kinase activity
CHD23_RS12170	COG0583	DNA-binding transcription factor activity
CHD23_RS12175	COG2814	Major facilitator Superfamily
CHD23_RS12190	COG3591	Belongs to the peptidase S1B family
CHD23_RS12210	COG0628	permease
CHD23_RS12215	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CHD23_RS12220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CHD23_RS12230	COG0531	amino acid
CHD23_RS12235	COG3136	membrane protein required for alginate biosynthesis
CHD23_RS12240	COG0745	RESPONSE REGULATOR receiver
CHD23_RS12250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CHD23_RS12255	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHD23_RS12260	COG2205	protein histidine kinase activity
CHD23_RS12285	COG5339	Protein conserved in bacteria
CHD23_RS12290	COG1609	Transcriptional regulator
CHD23_RS12295	COG1263	PTS System
CHD23_RS12295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD23_RS12300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CHD23_RS12310	COG0673	inositol 2-dehydrogenase activity
CHD23_RS12350	COG4659	FMN binding
CHD23_RS12360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHD23_RS12370	COG0625	glutathione transferase activity
CHD23_RS12390	COG3895	Periplasmic Protein
CHD23_RS12415	COG1566	PFAM secretion protein HlyD family protein
CHD23_RS12430	COG4989	oxidoreductase activity
CHD23_RS12435	COG3313	Fe-S protein
CHD23_RS12440	COG1309	transcriptional regulator
CHD23_RS12445	COG1902	pentaerythritol trinitrate reductase activity
CHD23_RS12460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CHD23_RS12465	COG0791	NLP P60 protein
CHD23_RS12490	COG0583	DNA-binding transcription factor activity
CHD23_RS12495	COG2814	Major facilitator Superfamily
CHD23_RS12500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHD23_RS12505	COG0307	riboflavin synthase, alpha
CHD23_RS12675	COG0784	Response regulator, receiver
CHD23_RS12675	COG2198	Histidine kinase
CHD23_RS12675	COG2205	protein histidine kinase activity
CHD23_RS12685	COG0789	Transcriptional regulator
CHD23_RS12690	COG3272	Protein of unknown function (DUF1722)
CHD23_RS12740	COG1376	ErfK ybiS ycfS ynhG family protein
CHD23_RS12755	COG0719	Fe-S assembly protein
CHD23_RS12760	COG0396	ATPase activity
CHD23_RS12765	COG0719	Fe-S assembly protein
CHD23_RS12770	COG0316	Belongs to the HesB IscA family
CHD23_RS12775	COG1823	symporter activity
CHD23_RS12785	COG2050	protein possibly involved in aromatic compounds catabolism
CHD23_RS12790	COG0277	FAD linked oxidase domain protein
CHD23_RS12790	COG0247	lactate metabolic process
CHD23_RS12795	COG0628	permease
CHD23_RS12815	COG0738	Major facilitator superfamily
CHD23_RS12820	COG2271	Major facilitator Superfamily
CHD23_RS12835	COG4670	ketone body catabolic process
CHD23_RS12840	COG1960	acyl-CoA dehydrogenase activity
CHD23_RS12845	COG1917	Cupin 2, conserved barrel domain protein
CHD23_RS12845	COG2207	Transcriptional regulator
CHD23_RS12850	COG2086	electron transfer activity
CHD23_RS12855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHD23_RS12860	COG0644	oxidoreductase
CHD23_RS12865	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CHD23_RS12870	COG0318	PFAM AMP-dependent synthetase and ligase
CHD23_RS12875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHD23_RS12875	COG0574	Belongs to the PEP-utilizing enzyme family
CHD23_RS12885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHD23_RS12890	COG4256	Hemin uptake protein
CHD23_RS12905	COG0791	NLP P60 protein
CHD23_RS12915	COG0386	Belongs to the glutathione peroxidase family
CHD23_RS12980	COG3137	Salt-induced outer membrane protein
CHD23_RS12985	COG1105	Belongs to the carbohydrate kinase PfkB family
CHD23_RS12995	COG3001	Fructosamine kinase
CHD23_RS13005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHD23_RS13010	COG1988	membrane-bound metal-dependent
CHD23_RS13015	COG1823	symporter activity
CHD23_RS13025	COG0753	catalase activity
CHD23_RS13035	COG1486	melibiose metabolic process
CHD23_RS13040	COG2169	Transcriptional regulator
CHD23_RS13040	COG1917	Cupin 2, conserved barrel domain protein
CHD23_RS13045	COG1447	Phosphotransferase system cellobiose-specific component IIA
CHD23_RS13050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHD23_RS13055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHD23_RS13060	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHD23_RS13070	COG0322	excinuclease ABC activity
CHD23_RS13075	COG3678	ATP-independent chaperone mediated protein folding
CHD23_RS13095	COG1012	belongs to the aldehyde dehydrogenase family
CHD23_RS13120	COG0494	nUDIX hydrolase
CHD23_RS13135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHD23_RS13145	COG0778	Nitroreductase
CHD23_RS13150	COG0616	signal peptide processing
CHD23_RS13155	COG0252	asparaginase activity
CHD23_RS13160	COG1335	isochorismatase
CHD23_RS13165	COG3139	Protein of unknown function (DUF1315)
CHD23_RS13185	COG0641	radical SAM
CHD23_RS13190	COG3713	MltA-interacting MipA family protein
CHD23_RS13195	COG2766	serine protein kinase
CHD23_RS13210	COG2199	diguanylate cyclase activity
CHD23_RS13215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHD23_RS13235	COG2207	Transcriptional regulator
CHD23_RS13240	COG2807	transmembrane transport
CHD23_RS13245	COG3189	MarR family transcriptional regulator
CHD23_RS13255	COG3042	response to heat
CHD23_RS13265	COG2261	transglycosylase associated protein
CHD23_RS13285	COG3615	Tellurite resistance protein tehB
CHD23_RS13300	COG1605	Chorismate mutase
CHD23_RS13310	COG0789	Transcriptional regulator
CHD23_RS13325	COG3443	Belongs to the bacterial solute-binding protein 9 family
CHD23_RS13340	COG0668	transmembrane transport
CHD23_RS13345	COG1124	(ABC) transporter
CHD23_RS13365	COG0747	negative chemotaxis
CHD23_RS13375	COG3038	cytochrome b561
CHD23_RS13385	COG0071	Belongs to the small heat shock protein (HSP20) family
CHD23_RS13545	COG3179	chitinase
CHD23_RS13585	COG0484	heat shock protein binding
CHD23_RS13595	COG1403	HNH endonuclease
CHD23_RS13605	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CHD23_RS13645	COG0582	viral genome integration into host DNA
CHD23_RS13650	COG0538	isocitrate dehydrogenase activity
CHD23_RS13680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHD23_RS13695	COG2850	peptidyl-arginine hydroxylation
CHD23_RS13720	COG1177	transmembrane transport
CHD23_RS13740	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHD23_RS13745	COG1136	(ABC) transporter
CHD23_RS13750	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHD23_RS13755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHD23_RS13760	COG1388	LysM domain
CHD23_RS13760	COG1376	ErfK ybiS ycfS ynhG family protein
CHD23_RS13770	COG1309	transcriptional regulator
CHD23_RS13775	COG3134	Outer membrane lipoprotein
CHD23_RS13780	COG1252	NADH dehydrogenase
CHD23_RS13805	COG5633	Lipoprotein
CHD23_RS13810	COG0537	adenosine 5'-monophosphoramidase activity
CHD23_RS13815	COG4773	Receptor
CHD23_RS13825	COG0084	hydrolase, TatD family'
CHD23_RS13830	COG0470	DNA polymerase III
CHD23_RS13840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHD23_RS13845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHD23_RS13850	COG3539	Fimbrial protein
CHD23_RS13880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHD23_RS13925	COG0564	pseudouridine synthase activity
CHD23_RS14030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHD23_RS14040	COG2999	glutathione oxidoreductase activity
CHD23_RS14075	COG3038	cytochrome b561
CHD23_RS14090	COG1560	Kdo2-lipid A biosynthetic process
CHD23_RS14110	COG5645	(Lipo)protein
CHD23_RS14115	COG2943	transferase activity, transferring hexosyl groups
CHD23_RS14130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHD23_RS14190	COG3381	protein complex oligomerization
CHD23_RS14220	COG0673	inositol 2-dehydrogenase activity
CHD23_RS14225	COG2814	Major facilitator Superfamily
CHD23_RS14245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHD23_RS14250	COG1737	Transcriptional regulator
CHD23_RS14280	COG1309	transcriptional regulator
CHD23_RS14285	COG3729	General stress protein
CHD23_RS14305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHD23_RS14310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CHD23_RS14310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHD23_RS14315	COG4232	protein-disulfide reductase activity
CHD23_RS14365	COG3971	2-oxopent-4-enoate hydratase activity
CHD23_RS14375	COG3384	dioxygenase
CHD23_RS14380	COG1012	belongs to the aldehyde dehydrogenase family
CHD23_RS14390	COG1846	Transcriptional regulator
CHD23_RS14395	COG2368	4-hydroxyphenylacetate
CHD23_RS14410	COG0745	RESPONSE REGULATOR receiver
CHD23_RS14415	COG2205	protein histidine kinase activity
CHD23_RS14475	COG0076	glutamate decarboxylase activity
CHD23_RS14525	COG0670	Belongs to the BI1 family
CHD23_RS14555	COG1832	CoA-binding protein
CHD23_RS14570	COG0210	DNA helicase
CHD23_RS14575	COG3304	Inner membrane component domain
CHD23_RS14580	COG1289	transmembrane transporter activity
CHD23_RS14585	COG3070	regulator of competence-specific genes
CHD23_RS14605	COG1067	ATP-dependent peptidase activity
CHD23_RS14615	COG3130	regulation of translation
CHD23_RS14620	COG3009	Protein conserved in bacteria
CHD23_RS14625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CHD23_RS14625	COG3008	intermembrane lipid transfer
CHD23_RS14630	COG2995	paraquat-inducible protein a
CHD23_RS14635	COG0488	(ABC) transporter
CHD23_RS14645	COG3217	Mosc domain protein beta barrel domain protein
CHD23_RS14645	COG0633	Ferredoxin
CHD23_RS14660	COG0308	aminopeptidase N
CHD23_RS14675	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CHD23_RS14685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHD23_RS14690	COG3108	Peptidase M15
CHD23_RS14700	COG2989	Protein conserved in bacteria
CHD23_RS14710	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CHD23_RS14720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHD23_RS14725	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CHD23_RS14730	COG3173	Aminoglycoside phosphotransferase
CHD23_RS14745	COG3214	Protein conserved in bacteria
CHD23_RS14760	COG2333	competence protein COMEC
CHD23_RS14760	COG0658	competence protein
CHD23_RS14770	COG0539	negative regulation of cytoplasmic translation
CHD23_RS14780	COG0501	Belongs to the peptidase M48B family
CHD23_RS14795	COG2323	membrane
CHD23_RS14800	COG1944	ATP diphosphatase activity
CHD23_RS14805	COG2116	formate transmembrane transporter activity
CHD23_RS14810	COG1882	Formate acetyltransferase
CHD23_RS14820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHD23_RS14835	COG0531	amino acid
CHD23_RS14855	COG1335	isochorismatase
CHD23_RS14860	COG3302	dmso reductase anchor subunit
CHD23_RS14865	COG0437	4 iron, 4 sulfur cluster binding
CHD23_RS14870	COG0243	molybdopterin cofactor binding
CHD23_RS14885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHD23_RS14910	COG0492	ferredoxin-NADP+ reductase activity
CHD23_RS14915	COG4988	ABC transporter
CHD23_RS14920	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CHD23_RS14940	COG0583	DNA-binding transcription factor activity
CHD23_RS14950	COG1335	isochorismatase
CHD23_RS14960	COG0542	response to heat
CHD23_RS14970	COG1278	Cold shock
CHD23_RS14980	COG0577	efflux transmembrane transporter activity
CHD23_RS14980	COG1136	(ABC) transporter
CHD23_RS14985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD23_RS14990	COG2990	Protein conserved in bacteria
CHD23_RS14995	COG3593	DNA synthesis involved in DNA repair
CHD23_RS15005	COG2431	L-lysine efflux transmembrane transporter activity
CHD23_RS15015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHD23_RS15020	COG0028	Belongs to the TPP enzyme family
CHD23_RS15025	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CHD23_RS15030	COG0702	epimerase
CHD23_RS15035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHD23_RS15040	COG3023	N-Acetylmuramoyl-L-alanine amidase
CHD23_RS15085	COG3179	chitinase
CHD23_RS15130	COG1126	abc transporter atp-binding protein
CHD23_RS15135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD23_RS15140	COG4215	(ABC) transporter
CHD23_RS15145	COG4160	amino acid transport
CHD23_RS15150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD23_RS15180	COG1177	transmembrane transport
CHD23_RS15185	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHD23_RS15190	COG3842	ATPase activity
CHD23_RS15195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CHD23_RS15235	COG3226	Transcriptional regulator
CHD23_RS15240	COG0738	Major facilitator superfamily
CHD23_RS15245	COG0561	phosphatase activity
CHD23_RS15250	COG2814	Major facilitator Superfamily
CHD23_RS15255	COG0671	phosphoesterase, PA-phosphatase related
CHD23_RS15260	COG1349	DNA-binding transcription factor activity
CHD23_RS15265	COG1686	Belongs to the peptidase S11 family
CHD23_RS15270	COG0625	glutathione transferase activity
CHD23_RS15280	COG2610	gluconate transmembrane transporter activity
CHD23_RS15285	COG0583	DNA-binding transcription factor activity
CHD23_RS15300	COG1960	acyl-CoA dehydrogenase activity
CHD23_RS15305	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CHD23_RS15320	COG2301	Belongs to the HpcH HpaI aldolase family
CHD23_RS15345	COG0747	negative chemotaxis
CHD23_RS15370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHD23_RS15375	COG1882	Formate acetyltransferase
CHD23_RS15380	COG0561	phosphatase activity
CHD23_RS15395	COG2271	Major facilitator Superfamily
CHD23_RS15405	COG0488	(ABC) transporter
CHD23_RS15410	COG1376	ErfK ybiS ycfS ynhG family protein
CHD23_RS15415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CHD23_RS15430	COG2194	sulfuric ester hydrolase activity
CHD23_RS15435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CHD23_RS15460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD23_RS15465	COG0765	amino acid transport
CHD23_RS15470	COG1126	abc transporter atp-binding protein
CHD23_RS15475	COG0668	transmembrane transport
CHD23_RS15485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CHD23_RS15495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHD23_RS15505	COG0513	Belongs to the DEAD box helicase family
CHD23_RS15510	COG1309	transcriptional regulator
CHD23_RS15520	COG1131	(ABC) transporter
CHD23_RS15525	COG0842	Transport permease protein
CHD23_RS15530	COG0842	Transport permease protein
CHD23_RS15540	COG3568	Endonuclease Exonuclease Phosphatase
CHD23_RS15545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHD23_RS15550	COG0392	lysyltransferase activity
CHD23_RS15555	COG0670	Belongs to the BI1 family
CHD23_RS15565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CHD23_RS15575	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHD23_RS15635	COG1881	PFAM PEBP family protein
CHD23_RS15665	COG4677	pectinesterase activity
CHD23_RS15680	COG0561	phosphatase activity
CHD23_RS15690	COG4149	molybdate abc transporter
CHD23_RS15695	COG0725	ABC transporter, periplasmic molybdate-binding protein
CHD23_RS15705	COG3585	molybdate ion transport
CHD23_RS15705	COG2005	Transcriptional regulator
CHD23_RS15710	COG1119	ATPase activity
CHD23_RS15730	COG2017	converts alpha-aldose to the beta-anomer
CHD23_RS15745	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS15750	COG0183	Belongs to the thiolase family
CHD23_RS15765	COG1120	ATPase activity
CHD23_RS15770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHD23_RS15775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHD23_RS15830	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CHD23_RS15835	COG2885	chlorophyll binding
CHD23_RS15845	COG3064	Membrane
CHD23_RS15850	COG0848	biopolymer transport protein
CHD23_RS15855	COG0811	peptide transport
CHD23_RS15860	COG0824	Thioesterase
CHD23_RS15865	COG3790	cyd operon protein YbgE
CHD23_RS15870	COG4890	Cyd operon protein YbgT
CHD23_RS15875	COG1294	oxidase, subunit
CHD23_RS15880	COG1271	oxidase subunit
CHD23_RS15885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHD23_RS15895	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHD23_RS15900	COG0567	Dehydrogenase, E1 component
CHD23_RS15915	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CHD23_RS15940	COG3180	Ammonia monooxygenase
CHD23_RS15970	COG1984	allophanate hydrolase subunit 2
CHD23_RS15975	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CHD23_RS16015	COG3157	Type VI secretion system effector, Hcp
CHD23_RS16045	COG2205	protein histidine kinase activity
CHD23_RS16050	COG0745	RESPONSE REGULATOR receiver
CHD23_RS16060	COG1982	Orn Lys Arg decarboxylase major
CHD23_RS16065	COG0531	amino acid
CHD23_RS16075	COG0033	Phosphoglucomutase
CHD23_RS16085	COG0596	Alpha beta hydrolase
CHD23_RS16100	COG0735	belongs to the Fur family
CHD23_RS16105	COG0583	DNA-binding transcription factor activity
CHD23_RS16110	COG1053	succinate dehydrogenase
CHD23_RS16150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CHD23_RS16155	COG1846	Transcriptional regulator
CHD23_RS16155	COG1940	carbohydrate kinase activity
CHD23_RS16160	COG0647	UMP catabolic process
CHD23_RS16165	COG0367	asparagine synthase
CHD23_RS16210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHD23_RS16220	COG1702	phosphate starvation-inducible protein PhoH
CHD23_RS16245	COG0765	amino acid transport
CHD23_RS16250	COG0765	amino acid transport
CHD23_RS16255	COG1126	abc transporter atp-binding protein
CHD23_RS16265	COG2888	peptidyl-tyrosine sulfation
CHD23_RS16280	COG1466	dna polymerase III delta subunit
CHD23_RS16295	COG0799	negative regulation of ribosome biogenesis
CHD23_RS16305	COG0768	penicillin binding
CHD23_RS16310	COG0772	Belongs to the SEDS family
CHD23_RS16320	COG1686	Belongs to the peptidase S11 family
CHD23_RS16335	COG0583	DNA-binding transcription factor activity
CHD23_RS16350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHD23_RS16370	COG3069	C4-dicarboxylate transmembrane transporter activity
CHD23_RS16375	COG4565	transcriptional regulatory protein
CHD23_RS16380	COG3290	protein histidine kinase activity
CHD23_RS16390	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CHD23_RS16400	COG2301	Belongs to the HpcH HpaI aldolase family
CHD23_RS16405	COG3051	citrate lyase alpha subunit
CHD23_RS16420	COG0471	metal ion transport
CHD23_RS16425	COG3719	Belongs to the RNase T2 family
CHD23_RS16430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHD23_RS16435	COG1063	alcohol dehydrogenase
CHD23_RS16455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CHD23_RS16460	COG0583	DNA-binding transcription factor activity
CHD23_RS16465	COG3969	phosphoadenosine phosphosulfate
CHD23_RS16470	COG1475	DNA binding
CHD23_RS16475	COG0436	Aminotransferase
CHD23_RS16480	COG0371	Dehydrogenase
CHD23_RS16485	COG2879	small protein
CHD23_RS16490	COG1966	Carbon starvation protein
CHD23_RS16500	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS16505	COG3433	isochorismatase activity
CHD23_RS16505	COG1535	isochorismatase
CHD23_RS16510	COG1021	2,3-dihydroxybenzoate-AMP ligase
CHD23_RS16515	COG1169	isochorismate synthase
CHD23_RS16520	COG4592	Periplasmic binding protein
CHD23_RS16530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHD23_RS16535	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHD23_RS16540	COG1120	ATPase activity
CHD23_RS16545	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CHD23_RS16550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHD23_RS16550	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CHD23_RS16555	COG3251	PFAM MbtH domain protein
CHD23_RS16560	COG2382	esterase
CHD23_RS16565	COG4771	TonB-dependent receptor
CHD23_RS16595	COG2315	Protein conserved in bacteria
CHD23_RS16620	COG3716	PTS system mannose fructose sorbose family IID component
CHD23_RS16630	COG2222	sugar isomerase
CHD23_RS16635	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CHD23_RS16635	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CHD23_RS16650	COG0668	transmembrane transport
CHD23_RS16655	COG1113	amino acid transport
CHD23_RS16665	COG3059	membrane
CHD23_RS16675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHD23_RS16680	COG2207	Transcriptional regulator
CHD23_RS16715	COG2246	polysaccharide biosynthetic process
CHD23_RS16720	COG0463	Glycosyl transferase, family 2
CHD23_RS16840	COG2501	S4 domain
CHD23_RS16850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHD23_RS16865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHD23_RS16870	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CHD23_RS16885	COG3157	Type VI secretion system effector, Hcp
CHD23_RS16895	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CHD23_RS16900	COG4181	ATPase activity
CHD23_RS16905	COG2755	lipolytic protein G-D-S-L family
CHD23_RS16910	COG0300	oxidoreductase activity
CHD23_RS16915	COG3118	belongs to the thioredoxin family
CHD23_RS16920	COG0390	transport system, permease component
CHD23_RS16925	COG4619	ABC transporter
CHD23_RS16930	COG0330	HflC and HflK could
CHD23_RS16935	COG1585	Membrane protein implicated in regulation of membrane protease activity
CHD23_RS16945	COG2217	Heavy metal translocating P-type atpase
CHD23_RS16950	COG3735	TraB family
CHD23_RS16965	COG2223	nitrite transmembrane transporter activity
CHD23_RS16970	COG4651	solute:proton antiporter activity
CHD23_RS16970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHD23_RS16980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD23_RS17035	COG2832	Protein of unknown function (DUF454)
CHD23_RS17040	COG3923	Primosomal replication protein n
CHD23_RS17055	COG3264	Mechanosensitive ion channel
CHD23_RS17055	COG1196	nuclear chromosome segregation
CHD23_RS17060	COG1309	transcriptional regulator
CHD23_RS17065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD23_RS17070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHD23_RS17085	COG0110	maltose O-acetyltransferase activity
CHD23_RS17105	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CHD23_RS17115	COG3695	enzyme binding
CHD23_RS17120	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CHD23_RS17125	COG1946	Acyl-CoA thioesterase
CHD23_RS17130	COG0004	ammonium transporteR
CHD23_RS17135	COG0347	Belongs to the P(II) protein family
CHD23_RS17140	COG1132	(ABC) transporter
CHD23_RS17145	COG1132	(ABC) transporter
CHD23_RS17150	COG1522	sequence-specific DNA binding
CHD23_RS17160	COG0561	phosphatase activity
CHD23_RS17165	COG4533	DNA binding
CHD23_RS17175	COG0824	Thioesterase
CHD23_RS17180	COG1555	photosystem II stabilization
CHD23_RS17185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHD23_RS17190	COG0776	regulation of translation
CHD23_RS17195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHD23_RS17230	COG0271	Belongs to the BolA IbaG family
CHD23_RS17235	COG3056	Lipoprotein
CHD23_RS17240	COG2223	nitrite transmembrane transporter activity
CHD23_RS17245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHD23_RS17250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHD23_RS17255	COG1845	cytochrome c oxidase, subunit III
CHD23_RS17260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CHD23_RS17275	COG2814	Major facilitator Superfamily
CHD23_RS17305	COG0142	geranyltranstransferase activity
CHD23_RS17315	COG0667	Aldo Keto reductase
CHD23_RS17320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CHD23_RS17340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHD23_RS17340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHD23_RS17350	COG4238	major outer membrane lipoprotein
CHD23_RS17365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHD23_RS17375	COG1862	Preprotein translocase
CHD23_RS17400	COG0450	alkyl hydroperoxide reductase
CHD23_RS17405	COG0366	Alpha amylase catalytic
CHD23_RS17420	COG5002	protein histidine kinase activity
CHD23_RS17435	COG0420	3'-5' exonuclease activity
CHD23_RS17440	COG0419	ATPase involved in DNA repair
CHD23_RS17445	COG2814	Major facilitator Superfamily
CHD23_RS17450	COG1940	carbohydrate kinase activity
CHD23_RS17465	COG4126	flavin adenine dinucleotide binding
CHD23_RS17485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHD23_RS17490	COG3706	GGDEF domain
CHD23_RS17535	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CHD23_RS17545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHD23_RS17560	COG0113	porphobilinogen synthase activity
CHD23_RS17595	COG1280	lysine exporter protein (LysE YggA)
CHD23_RS17610	COG1294	oxidase, subunit
CHD23_RS17615	COG1271	oxidase subunit
CHD23_RS17635	COG2814	Major facilitator Superfamily
CHD23_RS17645	COG0789	Transcriptional regulator
CHD23_RS17660	COG0402	S-adenosylhomocysteine deaminase activity
CHD23_RS17720	COG2195	Cleaves the N-terminal amino acid of tripeptides
CHD23_RS17730	COG3034	peptidoglycan biosynthetic process
CHD23_RS17735	COG0121	glutamine amidotransferase
CHD23_RS17750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHD23_RS17805	COG2226	methyltransferase
CHD23_RS17815	COG0741	lytic transglycosylase activity
CHD23_RS17815	COG1388	LysM domain
CHD23_RS17830	COG0583	DNA-binding transcription factor activity
CHD23_RS17885	COG3501	Rhs element vgr protein
CHD23_RS17965	COG3157	Type VI secretion system effector, Hcp
CHD23_RS17985	COG0582	viral genome integration into host DNA
CHD23_RS18020	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CHD23_RS18045	COG1720	tRNA m6t6A37 methyltransferase activity
CHD23_RS18055	COG3015	lipoprotein NlpE involved in copper resistance
CHD23_RS18060	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHD23_RS18075	COG4568	rho-dependent transcription termination
CHD23_RS18085	COG0346	lactoylglutathione lyase activity
CHD23_RS18090	COG1982	Orn Lys Arg decarboxylase major
CHD23_RS18150	COG0575	Belongs to the CDS family
CHD23_RS18210	COG0477	Major facilitator Superfamily
CHD23_RS18240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHD23_RS18245	COG2860	membrane
CHD23_RS18270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHD23_RS18275	COG1120	ATPase activity
CHD23_RS18280	COG4774	siderophore transport
CHD23_RS18285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHD23_RS18290	COG1643	Atp-dependent helicase
CHD23_RS18295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CHD23_RS18300	COG1489	DNA binding
CHD23_RS18310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHD23_RS18315	COG0617	tRNA 3'-terminal CCA addition
CHD23_RS18320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHD23_RS18345	COG0726	polysaccharide deacetylase
CHD23_RS18350	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS18355	COG0842	Transport permease protein
CHD23_RS18360	COG1131	(ABC) transporter
CHD23_RS18365	COG0288	reversible hydration of carbon dioxide
CHD23_RS18375	COG4993	Dehydrogenase
CHD23_RS18380	COG2132	Multicopper oxidase
CHD23_RS18400	COG1349	DNA-binding transcription factor activity
CHD23_RS18435	COG3064	Membrane
CHD23_RS18450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHD23_RS18455	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHD23_RS18460	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CHD23_RS18485	COG2211	Major facilitator Superfamily
CHD23_RS18490	COG3940	Belongs to the glycosyl hydrolase 43 family
CHD23_RS18495	COG3725	Membrane protein required for beta-lactamase induction
CHD23_RS18515	COG4969	Belongs to the N-Me-Phe pilin family
CHD23_RS18520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHD23_RS18525	COG1459	type II secretion system
CHD23_RS18550	COG0583	DNA-binding transcription factor activity
CHD23_RS18555	COG0667	Aldo Keto reductase
CHD23_RS18560	COG0494	nUDIX hydrolase
CHD23_RS18585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHD23_RS18590	COG0849	cell division
CHD23_RS18615	COG0772	Belongs to the SEDS family
CHD23_RS18630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHD23_RS18640	COG0768	penicillin binding
CHD23_RS18705	COG2814	Major facilitator Superfamily
CHD23_RS18735	COG0586	Pfam SNARE associated Golgi protein
CHD23_RS18785	COG0417	DNA replication proofreading
CHD23_RS18860	COG2271	Major facilitator Superfamily
CHD23_RS18870	COG0644	oxidoreductase
CHD23_RS18920	COG3119	arylsulfatase activity
CHD23_RS18985	COG1047	Peptidyl-prolyl cis-trans
CHD23_RS19000	COG0196	riboflavin kinase activity
CHD23_RS19015	COG0583	DNA-binding transcription factor activity
CHD23_RS19035	COG0641	radical SAM
CHD23_RS19040	COG3119	arylsulfatase activity
CHD23_RS19050	COG0737	Belongs to the 5'-nucleotidase family
CHD23_RS19135	COG4735	regulation of single-species biofilm formation
CHD23_RS19140	COG1584	GPR1 FUN34 yaaH family protein
CHD23_RS19145	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHD23_RS19155	COG1115	amino acid carrier protein
CHD23_RS19165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CHD23_RS19175	COG0527	aspartate kinase activity
CHD23_RS19175	COG0460	homoserine dehydrogenase
CHD23_RS19185	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CHD23_RS19200	COG0745	RESPONSE REGULATOR receiver
CHD23_RS19220	COG3121	Chaperone
CHD23_RS19245	COG3045	CreA protein
CHD23_RS19255	COG3708	Transcriptional regulator
CHD23_RS19255	COG2207	Transcriptional regulator
CHD23_RS19285	COG0488	(ABC) transporter
CHD23_RS19300	COG0560	Phosphoserine phosphatase
CHD23_RS19310	COG3726	membrane protein affecting hemolysin expression
CHD23_RS19340	COG1328	CTP reductase activity
CHD23_RS19345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHD23_RS19350	COG0084	hydrolase, TatD family'
CHD23_RS19355	COG4667	esterase of the alpha-beta hydrolase superfamily
CHD23_RS19365	COG2823	Periplasmic or secreted lipoprotein
CHD23_RS19375	COG1011	Hydrolase
CHD23_RS19385	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CHD23_RS19415	COG3706	GGDEF domain
CHD23_RS19420	COG4114	ferric iron reductase
CHD23_RS19425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHD23_RS19430	COG2197	response regulator
CHD23_RS19435	COG2197	response regulator
CHD23_RS19445	COG2966	Psort location CytoplasmicMembrane, score
CHD23_RS19460	COG1484	DNA-dependent DNA replication
CHD23_RS19475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHD23_RS19480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHD23_RS19485	COG3716	PTS system mannose fructose sorbose family IID component
CHD23_RS19490	COG3715	PTS system
CHD23_RS19495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD23_RS19510	COG0840	transmembrane signaling receptor activity
CHD23_RS19515	COG1966	Carbon starvation protein
CHD23_RS19525	COG2879	small protein
CHD23_RS19530	COG0523	cobalamin synthesis protein
CHD23_RS19545	COG1715	Restriction endonuclease
CHD23_RS19560	COG0732	type I restriction modification DNA specificity domain
CHD23_RS19580	COG1012	belongs to the aldehyde dehydrogenase family
CHD23_RS19595	COG2733	membrane
CHD23_RS19600	COG0477	Major facilitator Superfamily
CHD23_RS19605	COG3366	ferrous iron transmembrane transporter activity
CHD23_RS19610	COG0700	Nucleoside recognition
CHD23_RS19615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CHD23_RS19620	COG0583	DNA-binding transcription factor activity
CHD23_RS19640	COG0180	Tryptophanyl-tRNA synthetase
CHD23_RS19645	COG2186	Transcriptional regulator
CHD23_RS19670	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD23_RS19675	COG3715	PTS system
CHD23_RS19680	COG3716	PTS system mannose fructose sorbose family IID component
CHD23_RS19690	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CHD23_RS19705	COG5492	domain, Protein
CHD23_RS19730	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CHD23_RS19750	COG1470	cell adhesion involved in biofilm formation
CHD23_RS19750	COG1388	LysM domain
CHD23_RS19770	COG0305	Participates in initiation and elongation during chromosome replication
CHD23_RS19870	COG2003	Belongs to the UPF0758 family
CHD23_RS19890	COG1196	nuclear chromosome segregation
CHD23_RS19920	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CHD23_RS19935	COG3423	Transcriptional regulator
CHD23_RS19940	COG0531	amino acid
CHD23_RS19995	COG0494	nUDIX hydrolase
CHD23_RS20030	COG0582	viral genome integration into host DNA
CHD23_RS20040	COG1064	alcohol dehydrogenase
CHD23_RS20045	COG3265	gluconokinase activity
CHD23_RS20060	COG0795	lipopolysaccharide-transporting ATPase activity
CHD23_RS20065	COG0795	lipopolysaccharide-transporting ATPase activity
CHD23_RS20085	COG2927	DNA polymerase III (CHI subunit)
CHD23_RS20140	COG2731	YhcH YjgK YiaL family protein
CHD23_RS20150	COG2235	arginine
CHD23_RS20155	COG0549	Belongs to the carbamate kinase family
CHD23_RS20165	COG1288	antiporter activity
CHD23_RS20170	COG1438	arginine binding
CHD23_RS20215	COG1263	PTS System
CHD23_RS20215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD23_RS20220	COG0366	Alpha amylase catalytic
CHD23_RS20230	COG0602	queuosine metabolic process
CHD23_RS20245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS20245	COG3711	transcriptional antiterminator
CHD23_RS20260	COG3964	amidohydrolase
CHD23_RS20295	COG0312	modulator of DNA gyrase
CHD23_RS20335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHD23_RS20345	COG0840	transmembrane signaling receptor activity
CHD23_RS20355	COG2105	PFAM AIG2 family protein
CHD23_RS20375	COG1253	flavin adenine dinucleotide binding
CHD23_RS20390	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CHD23_RS20410	COG1733	regulation of RNA biosynthetic process
CHD23_RS20415	COG0702	epimerase
CHD23_RS20420	COG0697	spore germination
CHD23_RS20430	COG1113	amino acid transport
CHD23_RS20435	COG0545	Peptidyl-prolyl cis-trans isomerase
CHD23_RS20440	COG3061	Opacity-associated protein A
CHD23_RS20455	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHD23_RS20495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD23_RS20520	COG1073	alpha beta
CHD23_RS20525	COG3650	response to hydrogen peroxide
CHD23_RS20535	COG1960	acyl-CoA dehydrogenase activity
CHD23_RS20560	COG0557	exoribonuclease II activity
CHD23_RS20580	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CHD23_RS20585	COG1028	Short-chain dehydrogenase reductase Sdr
CHD23_RS20600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHD23_RS20610	COG0577	efflux transmembrane transporter activity
CHD23_RS20610	COG1136	(ABC) transporter
CHD23_RS20615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD23_RS20620	COG1132	(ABC) transporter
CHD23_RS20640	COG0330	HflC and HflK could
CHD23_RS20645	COG0330	HflC and HflK could
CHD23_RS20650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHD23_RS20675	COG0802	atpase or kinase
CHD23_RS20680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHD23_RS20680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHD23_RS20705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD23_RS20725	COG1511	domain protein
CHD23_RS20725	COG3264	Mechanosensitive ion channel
CHD23_RS20740	COG3121	Chaperone
CHD23_RS20745	COG3188	usher protein
CHD23_RS20750	COG3539	Fimbrial protein
CHD23_RS20785	COG1053	succinate dehydrogenase
CHD23_RS20790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CHD23_RS20820	COG5510	response to toxic substance
CHD23_RS20860	COG0531	amino acid
CHD23_RS20865	COG3030	protein affecting phage T7 exclusion by the F plasmid
CHD23_RS20870	COG1027	Aspartate ammonia-lyase
CHD23_RS20890	COG1309	transcriptional regulator
CHD23_RS20915	COG2197	response regulator
CHD23_RS20920	COG3204	pilus organization
CHD23_RS20930	COG4256	Hemin uptake protein
CHD23_RS20935	COG4771	TonB-dependent receptor
CHD23_RS20940	COG3720	iron ion transport
CHD23_RS20945	COG4558	Periplasmic binding protein
CHD23_RS20950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHD23_RS20960	COG3290	protein histidine kinase activity
CHD23_RS20965	COG4565	transcriptional regulatory protein
CHD23_RS20975	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CHD23_RS20980	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD23_RS20980	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD23_RS20995	COG2169	Transcriptional regulator
CHD23_RS21000	COG1982	Orn Lys Arg decarboxylase major
CHD23_RS21005	COG2207	Transcriptional regulator
CHD23_RS21010	COG0531	amino acid
CHD23_RS21040	COG2824	Alkylphosphonate utilization operon protein PhnA
CHD23_RS21045	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CHD23_RS21060	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CHD23_RS21070	COG1566	PFAM secretion protein HlyD family protein
CHD23_RS21075	COG1289	transmembrane transporter activity
CHD23_RS21090	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CHD23_RS21095	COG1301	dicarboxylic acid transport
CHD23_RS21100	COG4235	cytochrome complex assembly
CHD23_RS21105	COG3088	subunit of a heme lyase
CHD23_RS21110	COG1138	Cytochrome C-type biogenesis protein
CHD23_RS21115	COG3301	Polysulphide reductase, NrfD
CHD23_RS21120	COG0437	4 iron, 4 sulfur cluster binding
CHD23_RS21125	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CHD23_RS21140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHD23_RS21145	COG3162	membrane
CHD23_RS21155	COG1346	cytolysis
CHD23_RS21160	COG1380	Effector of murein hydrolase LrgA
CHD23_RS21165	COG0583	DNA-binding transcription factor activity
CHD23_RS21170	COG0025	NhaP-type Na H and K H
CHD23_RS21180	COG2252	PERMEase
CHD23_RS21205	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CHD23_RS21270	COG2315	Protein conserved in bacteria
CHD23_RS21280	COG3700	Belongs to the class B bacterial acid phosphatase family
CHD23_RS21315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHD23_RS21325	COG1063	alcohol dehydrogenase
CHD23_RS21335	COG0735	belongs to the Fur family
CHD23_RS21350	COG0534	Mate efflux family protein
CHD23_RS21360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CHD23_RS21405	COG3833	ABC-type maltose transport systems, permease component
CHD23_RS21410	COG2814	Major facilitator Superfamily
CHD23_RS21410	COG0477	Major facilitator Superfamily
CHD23_RS21420	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHD23_RS21445	COG0527	aspartate kinase activity
CHD23_RS21460	COG3122	Protein conserved in bacteria
CHD23_RS21510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CHD23_RS21555	COG0151	Belongs to the GarS family
CHD23_RS21620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHD23_RS21625	COG2104	thiamine diphosphate biosynthetic process
CHD23_RS21645	COG1447	Phosphotransferase system cellobiose-specific component IIA
CHD23_RS21690	COG0250	Participates in transcription elongation, termination and antitermination
CHD23_RS21820	COG0583	DNA-binding transcription factor activity
CHD23_RS21860	COG2207	Transcriptional regulator
CHD23_RS21870	COG0371	Dehydrogenase
CHD23_RS21885	COG0737	Belongs to the 5'-nucleotidase family
CHD23_RS21895	COG0527	aspartate kinase activity
CHD23_RS21895	COG0460	homoserine dehydrogenase
CHD23_RS21900	COG0626	cystathionine gamma-synthase activity
CHD23_RS21910	COG2211	Major facilitator Superfamily
CHD23_RS21925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHD23_RS21930	COG1609	Transcriptional regulator
CHD23_RS21935	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CHD23_RS21950	COG1575	Belongs to the MenA family. Type 1 subfamily
CHD23_RS21960	COG2721	sulfolactate sulfo-lyase activity
CHD23_RS21965	COG2721	sulfolactate sulfo-lyase activity
CHD23_RS21975	COG3290	protein histidine kinase activity
CHD23_RS21975	COG3829	transcription factor binding
CHD23_RS21985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHD23_RS21995	COG1494	fructose-1,6-bisphosphatase
CHD23_RS22005	COG3152	Membrane
CHD23_RS22020	COG0471	metal ion transport
CHD23_RS22070	COG4695	Portal protein
CHD23_RS22100	COG3678	ATP-independent chaperone mediated protein folding
CHD23_RS22105	COG0745	RESPONSE REGULATOR receiver
CHD23_RS22110	COG2205	protein histidine kinase activity
CHD23_RS22115	COG2258	MOSC domain
CHD23_RS22120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHD23_RS22135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHD23_RS22175	COG1454	alcohol dehydrogenase
CHD23_RS22190	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHD23_RS22230	COG0205	6-phosphofructokinase activity
CHD23_RS22300	COG3383	formate dehydrogenase (NAD+) activity
CHD23_RS22300	COG0243	molybdopterin cofactor binding
CHD23_RS22305	COG3383	formate dehydrogenase (NAD+) activity
CHD23_RS22305	COG0243	molybdopterin cofactor binding
CHD23_RS22310	COG0437	4 iron, 4 sulfur cluster binding
CHD23_RS22315	COG2864	formate dehydrogenase
CHD23_RS22330	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CHD23_RS22340	COG0456	acetyltransferase
CHD23_RS22355	COG1011	Hydrolase
CHD23_RS22360	COG1349	DNA-binding transcription factor activity
CHD23_RS22365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD23_RS22375	COG3684	Belongs to the aldolase LacD family
CHD23_RS22385	COG2017	converts alpha-aldose to the beta-anomer
CHD23_RS22390	COG1501	Belongs to the glycosyl hydrolase 31 family
CHD23_RS22475	COG0204	Acyl-transferase
CHD23_RS22490	COG3084	Protein conserved in bacteria
CHD23_RS22495	COG0746	molybdenum cofactor guanylyltransferase activity
CHD23_RS22500	COG1763	Mo-molybdopterin cofactor biosynthetic process
CHD23_RS22545	COG1739	Uncharacterized protein family UPF0029
CHD23_RS22570	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CHD23_RS22585	COG0805	protein transport
CHD23_RS22635	COG0641	radical SAM
CHD23_RS22655	COG0561	phosphatase activity
CHD23_RS22660	COG2267	carboxylic ester hydrolase activity
CHD23_RS22665	COG1280	lysine exporter protein (LysE YggA)
CHD23_RS22710	COG2962	Rard protein
CHD23_RS22740	COG1011	Hydrolase
CHD23_RS22790	COG2959	enzyme of heme biosynthesis
CHD23_RS22795	COG3071	HemY protein
CHD23_RS22840	COG2244	polysaccharide biosynthetic process
CHD23_RS22845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHD23_RS22850	COG0456	acetyltransferase
CHD23_RS22855	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CHD23_RS22860	COG1088	dTDP-glucose 4,6-dehydratase activity
CHD23_RS22865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHD23_RS22880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHD23_RS22900	COG3118	belongs to the thioredoxin family
CHD23_RS22925	COG1811	Na channel or pump
CHD23_RS22965	COG2376	Dihydroxyacetone kinase
CHD23_RS22995	COG3978	acetolactate synthase activity
CHD23_RS23060	COG2186	Transcriptional regulator
CHD23_RS23065	COG0477	Major facilitator Superfamily
CHD23_RS23070	COG1609	Transcriptional regulator
CHD23_RS23075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD23_RS23085	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHD23_RS23120	COG1522	sequence-specific DNA binding
CHD23_RS23125	COG0716	FMN binding
CHD23_RS23140	COG3312	ion transport
CHD23_RS23195	COG2188	Transcriptional regulator
CHD23_RS23205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHD23_RS23210	COG1447	Phosphotransferase system cellobiose-specific component IIA
CHD23_RS23225	COG2723	6-phospho-beta-galactosidase activity
CHD23_RS23230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHD23_RS23235	COG0573	inorganic phosphate transmembrane transporter activity
CHD23_RS23240	COG0581	inorganic phosphate transmembrane transporter activity
CHD23_RS23250	COG0704	Plays a role in the regulation of phosphate uptake
CHD23_RS23255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHD23_RS23260	COG2252	PERMEase
CHD23_RS23265	COG0431	NADPH-dependent FMN reductase
CHD23_RS23270	COG2091	lysine biosynthetic process via aminoadipic acid