locus-tag	class	description
E5O11_RS00005	COG0460	homoserine dehydrogenase
E5O11_RS00005	COG0527	aspartate kinase activity
E5O11_RS00015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E5O11_RS00025	COG1115	amino acid carrier protein
E5O11_RS00035	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5O11_RS00040	COG1584	GPR1 FUN34 yaaH family protein
E5O11_RS00045	COG4735	regulation of single-species biofilm formation
E5O11_RS00110	COG3188	usher protein
E5O11_RS00125	COG3539	Fimbrial protein
E5O11_RS00130	COG3121	Chaperone
E5O11_RS00150	COG0583	DNA-binding transcription factor activity
E5O11_RS00165	COG0737	Belongs to the 5'-nucleotidase family
E5O11_RS00175	COG3119	arylsulfatase activity
E5O11_RS00180	COG0641	radical SAM
E5O11_RS00200	COG0583	DNA-binding transcription factor activity
E5O11_RS00225	COG0196	riboflavin kinase activity
E5O11_RS00240	COG1047	Peptidyl-prolyl cis-trans
E5O11_RS00400	COG2271	Major facilitator Superfamily
E5O11_RS00420	COG3119	arylsulfatase activity
E5O11_RS00485	COG0417	DNA replication proofreading
E5O11_RS00525	COG0586	Pfam SNARE associated Golgi protein
E5O11_RS00615	COG0768	penicillin binding
E5O11_RS00625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E5O11_RS00640	COG0772	Belongs to the SEDS family
E5O11_RS00665	COG0849	cell division
E5O11_RS00670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E5O11_RS00690	COG0494	nUDIX hydrolase
E5O11_RS00725	COG1459	type II secretion system
E5O11_RS00730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E5O11_RS00735	COG4969	Belongs to the N-Me-Phe pilin family
E5O11_RS00755	COG3725	Membrane protein required for beta-lactamase induction
E5O11_RS00760	COG3940	Belongs to the glycosyl hydrolase 43 family
E5O11_RS00765	COG2211	Major facilitator Superfamily
E5O11_RS00780	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E5O11_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
E5O11_RS00790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5O11_RS00805	COG3064	Membrane
E5O11_RS00840	COG1349	DNA-binding transcription factor activity
E5O11_RS00865	COG4993	Dehydrogenase
E5O11_RS00875	COG0288	reversible hydration of carbon dioxide
E5O11_RS00880	COG1131	(ABC) transporter
E5O11_RS00885	COG0842	Transport permease protein
E5O11_RS00890	COG3539	Fimbrial protein
E5O11_RS00910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS00915	COG0726	polysaccharide deacetylase
E5O11_RS00935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5O11_RS00960	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E5O11_RS00965	COG1643	Atp-dependent helicase
E5O11_RS00970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E5O11_RS00975	COG4774	siderophore transport
E5O11_RS00980	COG1120	ATPase activity
E5O11_RS00985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E5O11_RS01005	COG3188	usher protein
E5O11_RS01010	COG3121	Chaperone
E5O11_RS01015	COG3539	Fimbrial protein
E5O11_RS01020	COG3539	Fimbrial protein
E5O11_RS01050	COG2860	membrane
E5O11_RS01075	COG3835	regulator
E5O11_RS01085	COG0477	Major facilitator Superfamily
E5O11_RS01135	COG0575	Belongs to the CDS family
E5O11_RS01195	COG1982	Orn Lys Arg decarboxylase major
E5O11_RS01200	COG0346	lactoylglutathione lyase activity
E5O11_RS01210	COG4568	rho-dependent transcription termination
E5O11_RS01225	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E5O11_RS01230	COG3015	lipoprotein NlpE involved in copper resistance
E5O11_RS01240	COG1720	tRNA m6t6A37 methyltransferase activity
E5O11_RS01305	COG0583	DNA-binding transcription factor activity
E5O11_RS01310	COG2814	Major facilitator Superfamily
E5O11_RS01320	COG2226	methyltransferase
E5O11_RS01325	COG1388	LysM domain
E5O11_RS01325	COG0741	lytic transglycosylase activity
E5O11_RS01335	COG2226	methyltransferase
E5O11_RS01440	COG3047	cAMP biosynthetic process
E5O11_RS01440	COG2885	chlorophyll binding
E5O11_RS01485	COG3209	COG3209 Rhs family protein
E5O11_RS01495	COG3209	COG3209 Rhs family protein
E5O11_RS01515	COG3209	COG3209 Rhs family protein
E5O11_RS01585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5O11_RS01600	COG0121	glutamine amidotransferase
E5O11_RS01605	COG3034	peptidoglycan biosynthetic process
E5O11_RS01620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E5O11_RS01625	COG2195	Cleaves the N-terminal amino acid of tripeptides
E5O11_RS01680	COG2814	Major facilitator Superfamily
E5O11_RS01695	COG0179	Fumarylacetoacetate (FAA) hydrolase
E5O11_RS01730	COG3188	usher protein
E5O11_RS01735	COG3121	Chaperone
E5O11_RS01740	COG3539	Fimbrial protein
E5O11_RS01755	COG2200	EAL domain
E5O11_RS01800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O11_RS01810	COG0789	Transcriptional regulator
E5O11_RS01820	COG2814	Major facilitator Superfamily
E5O11_RS01840	COG1271	oxidase subunit
E5O11_RS01845	COG1294	oxidase, subunit
E5O11_RS01865	COG1280	lysine exporter protein (LysE YggA)
E5O11_RS01900	COG0113	porphobilinogen synthase activity
E5O11_RS01915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E5O11_RS01925	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E5O11_RS01970	COG3706	GGDEF domain
E5O11_RS01975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E5O11_RS01995	COG4126	flavin adenine dinucleotide binding
E5O11_RS02010	COG1940	carbohydrate kinase activity
E5O11_RS02015	COG2814	Major facilitator Superfamily
E5O11_RS02020	COG0419	ATPase involved in DNA repair
E5O11_RS02025	COG0420	3'-5' exonuclease activity
E5O11_RS02035	COG5002	protein histidine kinase activity
E5O11_RS02050	COG0366	Alpha amylase catalytic
E5O11_RS02055	COG0450	alkyl hydroperoxide reductase
E5O11_RS02075	COG1862	Preprotein translocase
E5O11_RS02085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E5O11_RS02125	COG4238	major outer membrane lipoprotein
E5O11_RS02135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5O11_RS02135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5O11_RS02155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E5O11_RS02160	COG0667	Aldo Keto reductase
E5O11_RS02170	COG0142	geranyltranstransferase activity
E5O11_RS02205	COG2188	Transcriptional regulator
E5O11_RS02235	COG2814	Major facilitator Superfamily
E5O11_RS02260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E5O11_RS02265	COG1845	cytochrome c oxidase, subunit III
E5O11_RS02270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E5O11_RS02275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E5O11_RS02280	COG2223	nitrite transmembrane transporter activity
E5O11_RS02285	COG3056	Lipoprotein
E5O11_RS02290	COG0271	Belongs to the BolA IbaG family
E5O11_RS02315	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E5O11_RS02325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E5O11_RS02330	COG1555	photosystem II stabilization
E5O11_RS02335	COG0824	Thioesterase
E5O11_RS02345	COG4533	DNA binding
E5O11_RS02365	COG1522	sequence-specific DNA binding
E5O11_RS02370	COG1132	(ABC) transporter
E5O11_RS02375	COG1132	(ABC) transporter
E5O11_RS02385	COG0347	Belongs to the P(II) protein family
E5O11_RS02390	COG0004	ammonium transporteR
E5O11_RS02395	COG1946	Acyl-CoA thioesterase
E5O11_RS02400	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E5O11_RS02405	COG3695	enzyme binding
E5O11_RS02415	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5O11_RS02435	COG0110	maltose O-acetyltransferase activity
E5O11_RS02450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5O11_RS02455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O11_RS02460	COG1309	transcriptional regulator
E5O11_RS02465	COG3264	Mechanosensitive ion channel
E5O11_RS02465	COG1196	nuclear chromosome segregation
E5O11_RS02470	COG5464	transposase or invertase
E5O11_RS02480	COG3923	Primosomal replication protein n
E5O11_RS02485	COG2832	Protein of unknown function (DUF454)
E5O11_RS02530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS02535	COG4651	solute:proton antiporter activity
E5O11_RS02535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E5O11_RS02540	COG2223	nitrite transmembrane transporter activity
E5O11_RS02555	COG3735	TraB family
E5O11_RS02575	COG1585	Membrane protein implicated in regulation of membrane protease activity
E5O11_RS02580	COG0330	HflC and HflK could
E5O11_RS02585	COG4619	ABC transporter
E5O11_RS02590	COG0390	transport system, permease component
E5O11_RS02595	COG3118	belongs to the thioredoxin family
E5O11_RS02600	COG0300	oxidoreductase activity
E5O11_RS02605	COG2755	lipolytic protein G-D-S-L family
E5O11_RS02610	COG4181	ATPase activity
E5O11_RS02615	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E5O11_RS02625	COG1464	Belongs to the NlpA lipoprotein family
E5O11_RS02660	COG3960	tartronate-semialdehyde synthase activity
E5O11_RS02665	COG3622	Belongs to the hyi family
E5O11_RS02670	COG2084	Dehydrogenase
E5O11_RS02680	COG1953	Uracil, thiamine, allantoin
E5O11_RS02690	COG2233	PERMEase
E5O11_RS02695	COG1929	Belongs to the glycerate kinase type-1 family
E5O11_RS02700	COG3257	ureidoglycine aminohydrolase activity
E5O11_RS02705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E5O11_RS02710	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E5O11_RS02715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5O11_RS02720	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5O11_RS02730	COG0549	Belongs to the carbamate kinase family
E5O11_RS02735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E5O11_RS02740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E5O11_RS02750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E5O11_RS02770	COG1988	membrane-bound metal-dependent
E5O11_RS02775	COG2501	S4 domain
E5O11_RS02845	COG0582	viral genome integration into host DNA
E5O11_RS02860	COG0463	Glycosyl transferase, family 2
E5O11_RS02865	COG2246	polysaccharide biosynthetic process
E5O11_RS02875	COG5002	protein histidine kinase activity
E5O11_RS02880	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5O11_RS02885	COG2207	Transcriptional regulator
E5O11_RS02890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5O11_RS02900	COG3059	membrane
E5O11_RS02910	COG1113	amino acid transport
E5O11_RS02915	COG0668	transmembrane transport
E5O11_RS02925	COG3933	PFAM sigma-54 factor interaction domain-containing protein
E5O11_RS02925	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E5O11_RS02930	COG2222	sugar isomerase
E5O11_RS02940	COG3716	PTS system mannose fructose sorbose family IID component
E5O11_RS02965	COG2315	Protein conserved in bacteria
E5O11_RS02995	COG4771	TonB-dependent receptor
E5O11_RS03000	COG2382	esterase
E5O11_RS03005	COG3251	PFAM MbtH domain protein
E5O11_RS03010	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E5O11_RS03010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E5O11_RS03015	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E5O11_RS03020	COG1120	ATPase activity
E5O11_RS03025	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5O11_RS03030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5O11_RS03040	COG4592	Periplasmic binding protein
E5O11_RS03045	COG1169	isochorismate synthase
E5O11_RS03050	COG1021	2,3-dihydroxybenzoate-AMP ligase
E5O11_RS03055	COG1535	isochorismatase
E5O11_RS03055	COG3433	isochorismatase activity
E5O11_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
E5O11_RS03070	COG1966	Carbon starvation protein
E5O11_RS03075	COG2879	small protein
E5O11_RS03080	COG0371	Dehydrogenase
E5O11_RS03085	COG0436	Aminotransferase
E5O11_RS03090	COG1475	DNA binding
E5O11_RS03095	COG3969	phosphoadenosine phosphosulfate
E5O11_RS03100	COG0583	DNA-binding transcription factor activity
E5O11_RS03105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5O11_RS03125	COG0243	molybdopterin cofactor binding
E5O11_RS03145	COG1063	alcohol dehydrogenase
E5O11_RS03150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E5O11_RS03155	COG3719	Belongs to the RNase T2 family
E5O11_RS03160	COG0471	metal ion transport
E5O11_RS03175	COG3051	citrate lyase alpha subunit
E5O11_RS03180	COG2301	Belongs to the HpcH HpaI aldolase family
E5O11_RS03190	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E5O11_RS03195	COG3290	protein histidine kinase activity
E5O11_RS03200	COG4565	transcriptional regulatory protein
E5O11_RS03205	COG3069	C4-dicarboxylate transmembrane transporter activity
E5O11_RS03225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5O11_RS03240	COG0583	DNA-binding transcription factor activity
E5O11_RS03255	COG1686	Belongs to the peptidase S11 family
E5O11_RS03265	COG0772	Belongs to the SEDS family
E5O11_RS03270	COG0768	penicillin binding
E5O11_RS03280	COG0799	negative regulation of ribosome biogenesis
E5O11_RS03300	COG1466	dna polymerase III delta subunit
E5O11_RS03330	COG3829	transcription factor binding
E5O11_RS03330	COG3290	protein histidine kinase activity
E5O11_RS03335	COG2888	peptidyl-tyrosine sulfation
E5O11_RS03350	COG2214	Heat shock protein DnaJ domain protein
E5O11_RS03360	COG2214	Heat shock protein DnaJ domain protein
E5O11_RS03365	COG0443	Heat shock 70 kDa protein
E5O11_RS03380	COG1126	abc transporter atp-binding protein
E5O11_RS03385	COG0765	amino acid transport
E5O11_RS03390	COG0765	amino acid transport
E5O11_RS03415	COG1702	phosphate starvation-inducible protein PhoH
E5O11_RS03425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5O11_RS03470	COG0367	asparagine synthase
E5O11_RS03475	COG0647	UMP catabolic process
E5O11_RS03480	COG1940	carbohydrate kinase activity
E5O11_RS03480	COG1846	Transcriptional regulator
E5O11_RS03485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5O11_RS03525	COG1053	succinate dehydrogenase
E5O11_RS03530	COG0583	DNA-binding transcription factor activity
E5O11_RS03535	COG0735	belongs to the Fur family
E5O11_RS03550	COG0596	Alpha beta hydrolase
E5O11_RS03560	COG0033	Phosphoglucomutase
E5O11_RS03570	COG0531	amino acid
E5O11_RS03575	COG1982	Orn Lys Arg decarboxylase major
E5O11_RS03585	COG0745	RESPONSE REGULATOR receiver
E5O11_RS03590	COG2205	protein histidine kinase activity
E5O11_RS03635	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E5O11_RS03640	COG1984	allophanate hydrolase subunit 2
E5O11_RS03655	COG0582	viral genome integration into host DNA
E5O11_RS03695	COG1216	Glycosyl transferase, family 2
E5O11_RS03720	COG3180	Ammonia monooxygenase
E5O11_RS03735	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E5O11_RS03750	COG0567	Dehydrogenase, E1 component
E5O11_RS03755	COG0508	dehydrogenase complex catalyzes the overall conversion of
E5O11_RS03765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5O11_RS03770	COG1271	oxidase subunit
E5O11_RS03775	COG1294	oxidase, subunit
E5O11_RS03780	COG4890	Cyd operon protein YbgT
E5O11_RS03785	COG3790	cyd operon protein YbgE
E5O11_RS03790	COG0824	Thioesterase
E5O11_RS03795	COG0811	peptide transport
E5O11_RS03800	COG0848	biopolymer transport protein
E5O11_RS03805	COG3064	Membrane
E5O11_RS03815	COG2885	chlorophyll binding
E5O11_RS03820	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E5O11_RS03880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E5O11_RS03885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O11_RS03885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O11_RS03890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O11_RS03895	COG0583	DNA-binding transcription factor activity
E5O11_RS03900	COG0583	DNA-binding transcription factor activity
E5O11_RS03905	COG0490	domain, Protein
E5O11_RS03905	COG0471	metal ion transport
E5O11_RS03930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5O11_RS03935	COG1120	ATPase activity
E5O11_RS03945	COG2017	converts alpha-aldose to the beta-anomer
E5O11_RS03970	COG1119	ATPase activity
E5O11_RS03975	COG3585	molybdate ion transport
E5O11_RS03975	COG2005	Transcriptional regulator
E5O11_RS03985	COG0725	ABC transporter, periplasmic molybdate-binding protein
E5O11_RS03990	COG4149	molybdate abc transporter
E5O11_RS04000	COG0561	phosphatase activity
E5O11_RS04010	COG4677	pectinesterase activity
E5O11_RS04040	COG1881	PFAM PEBP family protein
E5O11_RS04100	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5O11_RS04110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E5O11_RS04120	COG0670	Belongs to the BI1 family
E5O11_RS04150	COG0392	lysyltransferase activity
E5O11_RS04160	COG3568	Endonuclease Exonuclease Phosphatase
E5O11_RS04170	COG0842	Transport permease protein
E5O11_RS04175	COG0842	Transport permease protein
E5O11_RS04180	COG1131	(ABC) transporter
E5O11_RS04190	COG1309	transcriptional regulator
E5O11_RS04195	COG0513	Belongs to the DEAD box helicase family
E5O11_RS04205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E5O11_RS04215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E5O11_RS04225	COG0668	transmembrane transport
E5O11_RS04230	COG1126	abc transporter atp-binding protein
E5O11_RS04235	COG0765	amino acid transport
E5O11_RS04240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O11_RS04255	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E5O11_RS04260	COG2194	sulfuric ester hydrolase activity
E5O11_RS04275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E5O11_RS04280	COG1376	ErfK ybiS ycfS ynhG family protein
E5O11_RS04285	COG0488	(ABC) transporter
E5O11_RS04305	COG0561	phosphatase activity
E5O11_RS04310	COG1882	Formate acetyltransferase
E5O11_RS04315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5O11_RS04365	COG2301	Belongs to the HpcH HpaI aldolase family
E5O11_RS04385	COG1960	acyl-CoA dehydrogenase activity
E5O11_RS04400	COG0583	DNA-binding transcription factor activity
E5O11_RS04405	COG2610	gluconate transmembrane transporter activity
E5O11_RS04410	COG2133	pyrroloquinoline quinone binding
E5O11_RS04415	COG0625	glutathione transferase activity
E5O11_RS04420	COG1686	Belongs to the peptidase S11 family
E5O11_RS04425	COG1349	DNA-binding transcription factor activity
E5O11_RS04430	COG0671	phosphoesterase, PA-phosphatase related
E5O11_RS04435	COG2814	Major facilitator Superfamily
E5O11_RS04440	COG0561	phosphatase activity
E5O11_RS04445	COG0738	Major facilitator superfamily
E5O11_RS04450	COG3226	Transcriptional regulator
E5O11_RS04495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E5O11_RS04500	COG3842	ATPase activity
E5O11_RS04505	COG1176	ABC-type spermidine putrescine transport system, permease component I
E5O11_RS04510	COG1177	transmembrane transport
E5O11_RS04540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O11_RS04545	COG4160	amino acid transport
E5O11_RS04550	COG4215	(ABC) transporter
E5O11_RS04555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O11_RS04560	COG1126	abc transporter atp-binding protein
E5O11_RS04575	COG3023	N-Acetylmuramoyl-L-alanine amidase
E5O11_RS04580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5O11_RS04585	COG0702	epimerase
E5O11_RS04590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E5O11_RS04595	COG0028	Belongs to the TPP enzyme family
E5O11_RS04600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5O11_RS04610	COG2431	L-lysine efflux transmembrane transporter activity
E5O11_RS04615	COG3593	DNA synthesis involved in DNA repair
E5O11_RS04620	COG2990	Protein conserved in bacteria
E5O11_RS04625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O11_RS04635	COG1278	Cold shock
E5O11_RS04645	COG0542	response to heat
E5O11_RS04670	COG1335	isochorismatase
E5O11_RS04680	COG0583	DNA-binding transcription factor activity
E5O11_RS04700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E5O11_RS04705	COG4988	ABC transporter
E5O11_RS04710	COG0492	ferredoxin-NADP+ reductase activity
E5O11_RS04730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E5O11_RS04740	COG0243	molybdopterin cofactor binding
E5O11_RS04745	COG0437	4 iron, 4 sulfur cluster binding
E5O11_RS04750	COG3302	dmso reductase anchor subunit
E5O11_RS04760	COG0531	amino acid
E5O11_RS04765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5O11_RS04780	COG1882	Formate acetyltransferase
E5O11_RS04785	COG2116	formate transmembrane transporter activity
E5O11_RS04790	COG1944	ATP diphosphatase activity
E5O11_RS04795	COG2323	membrane
E5O11_RS04810	COG0501	Belongs to the peptidase M48B family
E5O11_RS04820	COG0539	negative regulation of cytoplasmic translation
E5O11_RS04830	COG2333	competence protein COMEC
E5O11_RS04830	COG0658	competence protein
E5O11_RS04845	COG3214	Protein conserved in bacteria
E5O11_RS04865	COG3173	Aminoglycoside phosphotransferase
E5O11_RS04870	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E5O11_RS04875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E5O11_RS04885	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E5O11_RS04895	COG2989	Protein conserved in bacteria
E5O11_RS04900	COG3108	Peptidase M15
E5O11_RS04905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E5O11_RS04925	COG1522	sequence-specific DNA binding
E5O11_RS04940	COG1115	amino acid carrier protein
E5O11_RS04950	COG0582	viral genome integration into host DNA
E5O11_RS04970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O11_RS05005	COG1484	DNA-dependent DNA replication
E5O11_RS05110	COG4220	transposase activity
E5O11_RS05165	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O11_RS05190	COG2135	peptidase activity
E5O11_RS05210	COG0308	aminopeptidase N
E5O11_RS05225	COG3217	Mosc domain protein beta barrel domain protein
E5O11_RS05225	COG0633	Ferredoxin
E5O11_RS05235	COG0488	(ABC) transporter
E5O11_RS05240	COG2995	paraquat-inducible protein a
E5O11_RS05245	COG3008	intermembrane lipid transfer
E5O11_RS05245	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E5O11_RS05250	COG3009	Protein conserved in bacteria
E5O11_RS05255	COG3130	regulation of translation
E5O11_RS05265	COG1067	ATP-dependent peptidase activity
E5O11_RS05285	COG3070	regulator of competence-specific genes
E5O11_RS05290	COG1289	transmembrane transporter activity
E5O11_RS05295	COG3304	Inner membrane component domain
E5O11_RS05300	COG0210	DNA helicase
E5O11_RS05315	COG1832	CoA-binding protein
E5O11_RS05330	COG1881	PFAM PEBP family protein
E5O11_RS05350	COG0670	Belongs to the BI1 family
E5O11_RS05400	COG2205	protein histidine kinase activity
E5O11_RS05405	COG0745	RESPONSE REGULATOR receiver
E5O11_RS05420	COG2368	4-hydroxyphenylacetate
E5O11_RS05425	COG1846	Transcriptional regulator
E5O11_RS05435	COG1012	belongs to the aldehyde dehydrogenase family
E5O11_RS05440	COG3384	dioxygenase
E5O11_RS05450	COG3971	2-oxopent-4-enoate hydratase activity
E5O11_RS05500	COG4232	protein-disulfide reductase activity
E5O11_RS05505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5O11_RS05505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E5O11_RS05510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E5O11_RS05530	COG3729	General stress protein
E5O11_RS05535	COG1309	transcriptional regulator
E5O11_RS05555	COG1702	phosphate starvation-inducible protein PhoH
E5O11_RS05560	COG1737	Transcriptional regulator
E5O11_RS05565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E5O11_RS05585	COG2814	Major facilitator Superfamily
E5O11_RS05590	COG0673	inositol 2-dehydrogenase activity
E5O11_RS05625	COG3381	protein complex oligomerization
E5O11_RS05680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5O11_RS05705	COG5645	(Lipo)protein
E5O11_RS05720	COG1560	Kdo2-lipid A biosynthetic process
E5O11_RS05735	COG3038	cytochrome b561
E5O11_RS05770	COG2999	glutathione oxidoreductase activity
E5O11_RS05780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5O11_RS05870	COG1530	ribonuclease E activity
E5O11_RS05935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5O11_RS05940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E5O11_RS05945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E5O11_RS05955	COG0470	DNA polymerase III
E5O11_RS05960	COG0084	hydrolase, TatD family'
E5O11_RS05970	COG4773	Receptor
E5O11_RS05975	COG0537	adenosine 5'-monophosphoramidase activity
E5O11_RS05980	COG5633	Lipoprotein
E5O11_RS06005	COG1252	NADH dehydrogenase
E5O11_RS06010	COG3134	Outer membrane lipoprotein
E5O11_RS06015	COG1309	transcriptional regulator
E5O11_RS06025	COG1376	ErfK ybiS ycfS ynhG family protein
E5O11_RS06025	COG1388	LysM domain
E5O11_RS06030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E5O11_RS06035	COG4591	ABC-type transport system involved in lipoprotein release permease component
E5O11_RS06040	COG1136	(ABC) transporter
E5O11_RS06045	COG4591	ABC-type transport system involved in lipoprotein release permease component
E5O11_RS06065	COG1177	transmembrane transport
E5O11_RS06095	COG2850	peptidyl-arginine hydroxylation
E5O11_RS06110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E5O11_RS06140	COG0538	isocitrate dehydrogenase activity
E5O11_RS06210	COG0071	Belongs to the small heat shock protein (HSP20) family
E5O11_RS06220	COG3038	cytochrome b561
E5O11_RS06250	COG1124	(ABC) transporter
E5O11_RS06255	COG0668	transmembrane transport
E5O11_RS06270	COG3443	Belongs to the bacterial solute-binding protein 9 family
E5O11_RS06285	COG0789	Transcriptional regulator
E5O11_RS06300	COG1605	Chorismate mutase
E5O11_RS06310	COG3615	Tellurite resistance protein tehB
E5O11_RS06330	COG2261	transglycosylase associated protein
E5O11_RS06340	COG3042	response to heat
E5O11_RS06350	COG3189	MarR family transcriptional regulator
E5O11_RS06355	COG2807	transmembrane transport
E5O11_RS06360	COG2207	Transcriptional regulator
E5O11_RS06375	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E5O11_RS06380	COG2199	diguanylate cyclase activity
E5O11_RS06395	COG2766	serine protein kinase
E5O11_RS06400	COG3713	MltA-interacting MipA family protein
E5O11_RS06405	COG0641	radical SAM
E5O11_RS06410	COG0656	L-ascorbic acid biosynthetic process
E5O11_RS06430	COG3139	Protein of unknown function (DUF1315)
E5O11_RS06435	COG1335	isochorismatase
E5O11_RS06440	COG0252	asparaginase activity
E5O11_RS06445	COG0616	signal peptide processing
E5O11_RS06450	COG0778	Nitroreductase
E5O11_RS06475	COG0494	nUDIX hydrolase
E5O11_RS06510	COG3678	ATP-independent chaperone mediated protein folding
E5O11_RS06525	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5O11_RS06535	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E5O11_RS06540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E5O11_RS06545	COG1447	Phosphotransferase system cellobiose-specific component IIA
E5O11_RS06550	COG1917	Cupin 2, conserved barrel domain protein
E5O11_RS06550	COG2169	Transcriptional regulator
E5O11_RS06555	COG1486	melibiose metabolic process
E5O11_RS06565	COG0753	catalase activity
E5O11_RS06575	COG1823	symporter activity
E5O11_RS06580	COG1988	membrane-bound metal-dependent
E5O11_RS06585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5O11_RS06595	COG3001	Fructosamine kinase
E5O11_RS06605	COG1105	Belongs to the carbohydrate kinase PfkB family
E5O11_RS06610	COG3137	Salt-induced outer membrane protein
E5O11_RS06690	COG0386	Belongs to the glutathione peroxidase family
E5O11_RS06700	COG0791	NLP P60 protein
E5O11_RS06715	COG4256	Hemin uptake protein
E5O11_RS06730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5O11_RS06730	COG0574	Belongs to the PEP-utilizing enzyme family
E5O11_RS06735	COG0318	PFAM AMP-dependent synthetase and ligase
E5O11_RS06740	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E5O11_RS06745	COG0644	oxidoreductase
E5O11_RS06750	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E5O11_RS06755	COG2086	electron transfer activity
E5O11_RS06760	COG1917	Cupin 2, conserved barrel domain protein
E5O11_RS06760	COG2207	Transcriptional regulator
E5O11_RS06765	COG1960	acyl-CoA dehydrogenase activity
E5O11_RS06770	COG4670	ketone body catabolic process
E5O11_RS06785	COG2271	Major facilitator Superfamily
E5O11_RS06790	COG0738	Major facilitator superfamily
E5O11_RS06805	COG0628	permease
E5O11_RS06810	COG0247	lactate metabolic process
E5O11_RS06810	COG0277	FAD linked oxidase domain protein
E5O11_RS06815	COG2050	protein possibly involved in aromatic compounds catabolism
E5O11_RS06825	COG1823	symporter activity
E5O11_RS06830	COG0316	Belongs to the HesB IscA family
E5O11_RS06835	COG0719	Fe-S assembly protein
E5O11_RS06840	COG0396	ATPase activity
E5O11_RS06845	COG0719	Fe-S assembly protein
E5O11_RS06860	COG1376	ErfK ybiS ycfS ynhG family protein
E5O11_RS06880	COG0531	amino acid
E5O11_RS06885	COG2267	carboxylic ester hydrolase activity
E5O11_RS06895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS06930	COG3272	Protein of unknown function (DUF1722)
E5O11_RS06935	COG0789	Transcriptional regulator
E5O11_RS07115	COG0307	riboflavin synthase, alpha
E5O11_RS07120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E5O11_RS07125	COG2814	Major facilitator Superfamily
E5O11_RS07130	COG0583	DNA-binding transcription factor activity
E5O11_RS07150	COG0791	NLP P60 protein
E5O11_RS07155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E5O11_RS07175	COG1902	pentaerythritol trinitrate reductase activity
E5O11_RS07180	COG1309	transcriptional regulator
E5O11_RS07185	COG3313	Fe-S protein
E5O11_RS07190	COG4989	oxidoreductase activity
E5O11_RS07205	COG1566	PFAM secretion protein HlyD family protein
E5O11_RS07230	COG3895	Periplasmic Protein
E5O11_RS07250	COG0625	glutathione transferase activity
E5O11_RS07260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E5O11_RS07310	COG0673	inositol 2-dehydrogenase activity
E5O11_RS07325	COG1263	PTS System
E5O11_RS07325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O11_RS07330	COG5339	Protein conserved in bacteria
E5O11_RS07355	COG2205	protein histidine kinase activity
E5O11_RS07360	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
E5O11_RS07365	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E5O11_RS07375	COG0745	RESPONSE REGULATOR receiver
E5O11_RS07380	COG3136	membrane protein required for alginate biosynthesis
E5O11_RS07385	COG0531	amino acid
E5O11_RS07395	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E5O11_RS07400	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E5O11_RS07405	COG0628	permease
E5O11_RS07425	COG3591	Belongs to the peptidase S1B family
E5O11_RS07435	COG2814	Major facilitator Superfamily
E5O11_RS07440	COG0583	DNA-binding transcription factor activity
E5O11_RS07445	COG1940	carbohydrate kinase activity
E5O11_RS07485	COG3302	dmso reductase anchor subunit
E5O11_RS07490	COG0437	4 iron, 4 sulfur cluster binding
E5O11_RS07495	COG0243	molybdopterin cofactor binding
E5O11_RS07500	COG0243	molybdopterin cofactor binding
E5O11_RS07515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5O11_RS07535	COG1063	alcohol dehydrogenase
E5O11_RS07540	COG0477	Major facilitator Superfamily
E5O11_RS07545	COG0477	Major facilitator Superfamily
E5O11_RS07550	COG0246	Mannitol dehydrogenase
E5O11_RS07560	COG1802	Transcriptional regulator
E5O11_RS07565	COG4221	oxidoreductase activity
E5O11_RS07580	COG3729	General stress protein
E5O11_RS07585	COG1546	Belongs to the CinA family
E5O11_RS07590	COG3111	PFAM Bacterial OB fold (BOF) protein
E5O11_RS07600	COG2814	Major facilitator Superfamily
E5O11_RS07640	COG0583	DNA-binding transcription factor activity
E5O11_RS07645	COG1012	belongs to the aldehyde dehydrogenase family
E5O11_RS07660	COG3781	membrane
E5O11_RS07685	COG1773	rubredoxin
E5O11_RS07710	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E5O11_RS07715	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5O11_RS07725	COG2186	Transcriptional regulator
E5O11_RS07730	COG1063	alcohol dehydrogenase
E5O11_RS07735	COG2271	Major facilitator Superfamily
E5O11_RS07760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E5O11_RS07765	COG0251	oxidation-reduction process
E5O11_RS07815	COG1609	Transcriptional regulator
E5O11_RS07820	COG1757	Na H antiporter
E5O11_RS07825	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E5O11_RS07840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E5O11_RS07855	COG1764	response to oxidative stress
E5O11_RS07875	COG1064	alcohol dehydrogenase
E5O11_RS07880	COG2864	formate dehydrogenase
E5O11_RS07885	COG0437	4 iron, 4 sulfur cluster binding
E5O11_RS07925	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E5O11_RS07930	COG1140	nitrate reductase beta subunit
E5O11_RS07935	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E5O11_RS07940	COG2181	nitrate reductase activity
E5O11_RS07980	COG4772	TonB-dependent receptor
E5O11_RS07985	COG1802	Transcriptional regulator
E5O11_RS07990	COG2130	NADP-dependent
E5O11_RS08000	COG3238	Protein conserved in bacteria
E5O11_RS08040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5O11_RS08045	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E5O11_RS08070	COG0826	peptidase U32
E5O11_RS08075	COG1396	sequence-specific DNA binding
E5O11_RS08080	COG3135	benzoate transporter
E5O11_RS08090	COG0500	methyltransferase
E5O11_RS08095	COG1275	C4-dicarboxylate transporter malic acid transport protein
E5O11_RS08100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E5O11_RS08105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5O11_RS08115	COG3414	Phosphotransferase system galactitol-specific IIB component
E5O11_RS08120	COG3775	system Galactitol-specific IIC component
E5O11_RS08125	COG0434	BtpA family
E5O11_RS08130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS08135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E5O11_RS08140	COG1349	DNA-binding transcription factor activity
E5O11_RS08150	COG1304	FMN binding
E5O11_RS08155	COG2353	YceI-like domain
E5O11_RS08165	COG2272	Belongs to the type-B carboxylesterase lipase family
E5O11_RS08170	COG5383	Protein conserved in bacteria
E5O11_RS08175	COG0583	DNA-binding transcription factor activity
E5O11_RS08180	COG0840	transmembrane signaling receptor activity
E5O11_RS08215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O11_RS08220	COG0765	amino acid transport
E5O11_RS08230	COG0765	amino acid transport
E5O11_RS08240	COG0500	methyltransferase
E5O11_RS08245	COG3038	cytochrome b561
E5O11_RS08250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E5O11_RS08255	COG1643	Atp-dependent helicase
E5O11_RS08270	COG3784	Protein of unknown function (DUF1318)
E5O11_RS08280	COG2911	Protein conserved in bacteria
E5O11_RS08285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E5O11_RS08290	COG3187	Heat shock protein
E5O11_RS08295	COG3042	response to heat
E5O11_RS08305	COG0674	pyruvate-flavodoxin oxidoreductase activity
E5O11_RS08305	COG1013	pyruvate-flavodoxin oxidoreductase activity
E5O11_RS08305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E5O11_RS08305	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5O11_RS08315	COG2076	Multidrug Resistance protein
E5O11_RS08335	COG0513	Belongs to the DEAD box helicase family
E5O11_RS08350	COG0840	transmembrane signaling receptor activity
E5O11_RS08355	COG2840	Smr protein MutS2
E5O11_RS08375	COG3182	Iron-regulated membrane protein
E5O11_RS08380	COG0668	transmembrane transport
E5O11_RS08400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E5O11_RS08435	COG1309	transcriptional regulator
E5O11_RS08440	COG1028	Short-chain dehydrogenase reductase Sdr
E5O11_RS08445	COG0656	L-ascorbic acid biosynthetic process
E5O11_RS08450	COG0583	DNA-binding transcription factor activity
E5O11_RS08460	COG4166	transmembrane transport
E5O11_RS08465	COG2866	Carboxypeptidase
E5O11_RS08470	COG4948	Mandelate Racemase Muconate Lactonizing
E5O11_RS08490	COG3106	COG3106 Predicted ATPase
E5O11_RS08495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5O11_RS08505	COG1983	PspC domain protein
E5O11_RS08515	COG1842	Phage shock protein A
E5O11_RS08520	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E5O11_RS08575	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5O11_RS08575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5O11_RS08585	COG5001	Diguanylate cyclase
E5O11_RS08595	COG1349	DNA-binding transcription factor activity
E5O11_RS08615	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E5O11_RS08620	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E5O11_RS08625	COG0671	phosphoesterase, PA-phosphatase related
E5O11_RS08665	COG0616	signal peptide processing
E5O11_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
E5O11_RS08685	COG0009	L-threonylcarbamoyladenylate synthase
E5O11_RS08725	COG3729	General stress protein
E5O11_RS08730	COG3685	Protein conserved in bacteria
E5O11_RS08735	COG3685	Protein conserved in bacteria
E5O11_RS08740	COG3546	catalase activity
E5O11_RS08750	COG0727	PFAM Uncharacterised protein family (UPF0153)
E5O11_RS08775	COG2350	Protein conserved in bacteria
E5O11_RS08795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E5O11_RS08825	COG2095	MarC family integral membrane protein
E5O11_RS08830	COG1454	alcohol dehydrogenase
E5O11_RS08830	COG1012	belongs to the aldehyde dehydrogenase family
E5O11_RS08845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E5O11_RS08850	COG0745	RESPONSE REGULATOR receiver
E5O11_RS08855	COG1752	Esterase of the alpha-beta hydrolase superfamily
E5O11_RS08865	COG0788	formyltetrahydrofolate deformylase activity
E5O11_RS08910	COG2181	nitrate reductase activity
E5O11_RS08915	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E5O11_RS08920	COG1140	nitrate reductase beta subunit
E5O11_RS08925	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E5O11_RS08930	COG2223	nitrite transmembrane transporter activity
E5O11_RS08935	COG3850	Histidine kinase
E5O11_RS08940	COG2197	response regulator
E5O11_RS08945	COG4932	domain protein
E5O11_RS08950	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E5O11_RS08955	COG4572	Cation transport regulator
E5O11_RS08960	COG0387	Pfam Sodium calcium exchanger
E5O11_RS09010	COG0659	secondary active sulfate transmembrane transporter activity
E5O11_RS09025	COG0012	GTP binding
E5O11_RS09035	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5O11_RS09045	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E5O11_RS09050	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5O11_RS09055	COG1999	signal sequence binding
E5O11_RS09060	COG1773	rubredoxin
E5O11_RS09065	COG1271	oxidase subunit
E5O11_RS09070	COG1294	oxidase, subunit
E5O11_RS09080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E5O11_RS09105	COG1619	proteins homologs of microcin C7 resistance protein MccF
E5O11_RS09125	COG2719	SpoVR family
E5O11_RS09165	COG0179	Fumarylacetoacetate (FAA) hydrolase
E5O11_RS09180	COG2894	cell division
E5O11_RS09190	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E5O11_RS09200	COG3065	identical protein binding
E5O11_RS09210	COG1199	ATP-dependent helicase activity
E5O11_RS09215	COG0251	oxidation-reduction process
E5O11_RS09235	COG1760	l-serine dehydratase
E5O11_RS09240	COG2200	EAL domain
E5O11_RS09245	COG1253	flavin adenine dinucleotide binding
E5O11_RS09250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O11_RS09250	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS09255	COG3715	PTS system
E5O11_RS09260	COG3716	PTS system mannose fructose sorbose family IID component
E5O11_RS09275	COG2226	methyltransferase
E5O11_RS09280	COG0768	penicillin binding
E5O11_RS09310	COG1414	Transcriptional regulator
E5O11_RS09315	COG2814	Major facilitator Superfamily
E5O11_RS09335	COG1956	GAF domain-containing protein
E5O11_RS09340	COG2995	paraquat-inducible protein a
E5O11_RS09345	COG3008	intermembrane lipid transfer
E5O11_RS09380	COG5562	phage envelope protein
E5O11_RS09390	COG0454	-acetyltransferase
E5O11_RS09495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O11_RS09510	COG1276	copper resistance
E5O11_RS09515	COG2372	response to copper ion
E5O11_RS09525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5O11_RS09530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O11_RS09535	COG1770	oligopeptidase
E5O11_RS09540	COG2979	Protein of unknown function (DUF533)
E5O11_RS09550	COG3141	response to X-ray
E5O11_RS09560	COG0800	Aldolase
E5O11_RS09565	COG0129	dihydroxy-acid dehydratase activity
E5O11_RS09570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E5O11_RS09575	COG1737	Transcriptional regulator
E5O11_RS09585	COG1560	Kdo2-lipid A biosynthetic process
E5O11_RS09590	COG0739	heme binding
E5O11_RS09595	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E5O11_RS09605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5O11_RS09640	COG0494	nUDIX hydrolase
E5O11_RS09650	COG1335	isochorismatase
E5O11_RS09655	COG1801	Protein of unknown function DUF72
E5O11_RS09660	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E5O11_RS09680	COG3102	Protein conserved in bacteria
E5O11_RS09695	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E5O11_RS09800	COG1528	Iron-storage protein
E5O11_RS09815	COG1528	Iron-storage protein
E5O11_RS09825	COG0814	amino acid
E5O11_RS09830	COG3318	Belongs to the UPF0149 family
E5O11_RS09830	COG3012	SEC-C Motif Domain Protein
E5O11_RS09875	COG2197	response regulator
E5O11_RS09890	COG2197	response regulator
E5O11_RS09895	COG1126	abc transporter atp-binding protein
E5O11_RS09900	COG0765	amino acid transport
E5O11_RS09910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O11_RS09970	COG0425	Belongs to the sulfur carrier protein TusA family
E5O11_RS10075	COG5475	Uncharacterized small protein (DUF2158)
E5O11_RS10080	COG2354	Protein conserved in bacteria
E5O11_RS10085	COG0697	spore germination
E5O11_RS10090	COG3727	T/G mismatch-specific endonuclease activity
E5O11_RS10095	COG0270	DNA (cytosine-5-)-methyltransferase activity
E5O11_RS10100	COG1418	mRNA catabolic process
E5O11_RS10110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E5O11_RS10185	COG3778	Protein conserved in bacteria
E5O11_RS10190	COG3299	homolog of phage Mu protein gp47
E5O11_RS10235	COG4386	tail sheath protein
E5O11_RS10280	COG4695	Portal protein
E5O11_RS10290	COG1802	Transcriptional regulator
E5O11_RS10290	COG4626	Terminase
E5O11_RS10320	COG3179	chitinase
E5O11_RS10345	COG0484	heat shock protein binding
E5O11_RS10350	COG1403	HNH endonuclease
E5O11_RS10360	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E5O11_RS10365	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E5O11_RS10385	COG3646	Phage regulatory protein
E5O11_RS10425	COG5532	Uncharacterized conserved protein (DUF2303)
E5O11_RS10430	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E5O11_RS10480	COG0582	viral genome integration into host DNA
E5O11_RS10535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E5O11_RS10560	COG0534	Mate efflux family protein
E5O11_RS10725	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E5O11_RS10740	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
E5O11_RS10755	COG1012	belongs to the aldehyde dehydrogenase family
E5O11_RS10755	COG1454	alcohol dehydrogenase
E5O11_RS10760	COG4656	Part of a membrane complex involved in electron transport
E5O11_RS10795	COG1289	transmembrane transporter activity
E5O11_RS10835	COG2925	Exonuclease
E5O11_RS10840	COG0531	amino acid
E5O11_RS10850	COG0583	DNA-binding transcription factor activity
E5O11_RS10855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5O11_RS11015	COG2327	Polysaccharide pyruvyl transferase
E5O11_RS11020	COG2244	polysaccharide biosynthetic process
E5O11_RS11025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E5O11_RS11040	COG0297	glycogen (starch) synthase activity
E5O11_RS11050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5O11_RS11055	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E5O11_RS11060	COG0110	maltose O-acetyltransferase activity
E5O11_RS11065	COG1216	Glycosyl transferase, family 2
E5O11_RS11075	COG0438	transferase activity, transferring glycosyl groups
E5O11_RS11080	COG1045	serine acetyltransferase
E5O11_RS11085	COG0463	Glycosyl transferase, family 2
E5O11_RS11105	COG1253	flavin adenine dinucleotide binding
E5O11_RS11110	COG2982	Protein involved in outer membrane biogenesis
E5O11_RS11125	COG5001	Diguanylate cyclase
E5O11_RS11125	COG5002	protein histidine kinase activity
E5O11_RS11125	COG3447	MASE1 domain protein
E5O11_RS11130	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E5O11_RS11135	COG0443	Heat shock 70 kDa protein
E5O11_RS11165	COG2205	protein histidine kinase activity
E5O11_RS11170	COG0745	RESPONSE REGULATOR receiver
E5O11_RS11190	COG0826	peptidase U32
E5O11_RS11215	COG1830	Aldolase
E5O11_RS11220	COG2211	Major facilitator Superfamily
E5O11_RS11225	COG1397	ADP-ribosylglycohydrolase
E5O11_RS11230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS11235	COG2188	Transcriptional regulator
E5O11_RS11250	COG5455	response to cobalt ion
E5O11_RS11255	COG3539	Fimbrial protein
E5O11_RS11260	COG3188	usher protein
E5O11_RS11265	COG3121	Chaperone
E5O11_RS11290	COG4808	Protein conserved in bacteria
E5O11_RS11300	COG4807	Protein conserved in bacteria
E5O11_RS11310	COG3275	phosphorelay sensor kinase activity
E5O11_RS11325	COG1174	glycine betaine transport
E5O11_RS11330	COG1125	glycine betaine transport
E5O11_RS11335	COG1174	glycine betaine transport
E5O11_RS11340	COG1732	Glycine betaine
E5O11_RS11350	COG0277	FAD linked oxidase domain protein
E5O11_RS11355	COG1686	Belongs to the peptidase S11 family
E5O11_RS11365	COG0586	Pfam SNARE associated Golgi protein
E5O11_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
E5O11_RS11375	COG1538	Outer membrane efflux protein
E5O11_RS11390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5O11_RS11395	COG0625	glutathione transferase activity
E5O11_RS11410	COG2271	Major facilitator Superfamily
E5O11_RS11425	COG1346	cytolysis
E5O11_RS11435	COG2949	membrane
E5O11_RS11475	COG2311	Membrane
E5O11_RS11495	COG1760	l-serine dehydratase
E5O11_RS11500	COG0560	Phosphoserine phosphatase
E5O11_RS11505	COG2271	Major facilitator Superfamily
E5O11_RS11510	COG4771	TonB-dependent receptor
E5O11_RS11515	COG0833	amino acid
E5O11_RS11520	COG0583	DNA-binding transcription factor activity
E5O11_RS11525	COG2855	membrane
E5O11_RS11535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O11_RS11535	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E5O11_RS11535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O11_RS11540	COG1105	Belongs to the carbohydrate kinase PfkB family
E5O11_RS11575	COG0523	cobalamin synthesis protein
E5O11_RS11580	COG0671	phosphoesterase, PA-phosphatase related
E5O11_RS11585	COG0791	NLP P60 protein
E5O11_RS11590	COG2200	EAL domain
E5O11_RS11595	COG4166	transmembrane transport
E5O11_RS11600	COG4174	ABC transporter (Permease)
E5O11_RS11605	COG4239	(ABC) transporter, permease
E5O11_RS11610	COG4172	Belongs to the ABC transporter superfamily
E5O11_RS11620	COG2814	Major facilitator Superfamily
E5O11_RS11630	COG1061	Type III restriction enzyme res subunit
E5O11_RS11725	COG1403	HNH endonuclease
E5O11_RS11745	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O11_RS11760	COG2197	response regulator
E5O11_RS11765	COG3088	subunit of a heme lyase
E5O11_RS11765	COG4235	cytochrome complex assembly
E5O11_RS11775	COG1138	Cytochrome C-type biogenesis protein
E5O11_RS11785	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O11_RS11790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O11_RS11795	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O11_RS11800	COG4133	protoheme IX ABC transporter activity
E5O11_RS11805	COG3005	denitrification pathway
E5O11_RS11810	COG3043	anaerobic respiration
E5O11_RS11815	COG0348	domain, Protein
E5O11_RS11820	COG0437	4 iron, 4 sulfur cluster binding
E5O11_RS11830	COG3062	negative regulation of establishment of protein localization
E5O11_RS11835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O11_RS11835	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O11_RS11845	COG4615	Cyclic peptide transporter
E5O11_RS11870	COG2198	Histidine kinase
E5O11_RS11870	COG0642	Histidine kinase
E5O11_RS11890	COG4948	Mandelate Racemase Muconate Lactonizing
E5O11_RS11920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5O11_RS11925	COG2814	Major facilitator Superfamily
E5O11_RS11930	COG0583	DNA-binding transcription factor activity
E5O11_RS11935	COG0584	glycerophosphoryl diester phosphodiesterase
E5O11_RS11940	COG2271	Major facilitator Superfamily
E5O11_RS11945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E5O11_RS11955	COG0247	lactate metabolic process
E5O11_RS11975	COG2271	Major facilitator Superfamily
E5O11_RS11985	COG1414	Transcriptional regulator
E5O11_RS12075	COG1169	isochorismate synthase
E5O11_RS12080	COG4575	ribosome binding
E5O11_RS12085	COG2153	protein acetylation
E5O11_RS12095	COG0835	chemotaxis
E5O11_RS12095	COG0784	Response regulator, receiver
E5O11_RS12100	COG2304	oxidoreductase activity
E5O11_RS12115	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5O11_RS12120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E5O11_RS12130	COG0839	Belongs to the complex I subunit 6 family
E5O11_RS12180	COG0583	DNA-binding transcription factor activity
E5O11_RS12185	COG0436	Aminotransferase
E5O11_RS12200	COG0471	metal ion transport
E5O11_RS12200	COG0490	domain, Protein
E5O11_RS12205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5O11_RS12230	COG1288	antiporter activity
E5O11_RS12235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E5O11_RS12240	COG3959	Transketolase, thiamine diphosphate binding domain
E5O11_RS12245	COG3037	sugar-specific permease SgaT UlaA
E5O11_RS12255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS12260	COG1609	Transcriptional regulator
E5O11_RS12270	COG0622	Phosphoesterase
E5O11_RS12275	COG0625	glutathione transferase activity
E5O11_RS12280	COG0625	glutathione transferase activity
E5O11_RS12285	COG1090	epimerase
E5O11_RS12320	COG0833	amino acid
E5O11_RS12325	COG3457	Alanine racemase
E5O11_RS12330	COG0531	amino acid
E5O11_RS12340	COG3829	transcription factor binding
E5O11_RS12345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E5O11_RS12350	COG1286	toxin biosynthetic process
E5O11_RS12355	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E5O11_RS12360	COG0285	dihydrofolate synthase activity
E5O11_RS12370	COG0586	Pfam SNARE associated Golgi protein
E5O11_RS12380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E5O11_RS12405	COG3423	Transcriptional regulator
E5O11_RS12430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5O11_RS12445	COG3101	peptidyl-lysine hydroxylation
E5O11_RS12450	COG0730	response to heat
E5O11_RS12475	COG2062	phosphohistidine phosphatase, SixA
E5O11_RS12490	COG3691	Protein conserved in bacteria
E5O11_RS12505	COG2116	formate transmembrane transporter activity
E5O11_RS12545	COG1560	Kdo2-lipid A biosynthetic process
E5O11_RS12555	COG0436	Aminotransferase
E5O11_RS12570	COG3961	Belongs to the TPP enzyme family
E5O11_RS12575	COG0667	Aldo Keto reductase
E5O11_RS12590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E5O11_RS12595	COG2200	EAL domain
E5O11_RS12595	COG2199	diguanylate cyclase activity
E5O11_RS12610	COG3415	Transposase
E5O11_RS12615	COG3415	Transposase
E5O11_RS12645	COG0583	DNA-binding transcription factor activity
E5O11_RS12655	COG2211	Major facilitator Superfamily
E5O11_RS12660	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E5O11_RS12670	COG0583	DNA-binding transcription factor activity
E5O11_RS12675	COG0385	Bile acid
E5O11_RS12680	COG3530	Putative quorum-sensing-regulated virulence factor
E5O11_RS12705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS12760	COG4208	sulfate ABC transporter
E5O11_RS12785	COG2837	iron assimilation
E5O11_RS12920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E5O11_RS12930	COG5342	invasion associated locus B
E5O11_RS12945	COG0493	'glutamate synthase
E5O11_RS12945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O11_RS12950	COG3850	Histidine kinase
E5O11_RS12955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5O11_RS12965	COG1393	Belongs to the ArsC family
E5O11_RS12985	COG2321	neutral zinc metallopeptidase
E5O11_RS12995	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E5O11_RS13005	COG2716	regulation of RNA biosynthetic process
E5O11_RS13010	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5O11_RS13015	COG1929	Belongs to the glycerate kinase type-1 family
E5O11_RS13020	COG0628	permease
E5O11_RS13030	COG1393	Belongs to the ArsC family
E5O11_RS13040	COG2233	PERMEase
E5O11_RS13055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E5O11_RS13070	COG2200	EAL domain
E5O11_RS13110	COG0516	GMP reductase activity
E5O11_RS13110	COG0517	IMP dehydrogenase activity
E5O11_RS13150	COG1645	bacterial-type flagellum-dependent swarming motility
E5O11_RS13165	COG2976	Protein conserved in bacteria
E5O11_RS13205	COG0437	4 iron, 4 sulfur cluster binding
E5O11_RS13210	COG0243	molybdopterin cofactor binding
E5O11_RS13215	COG4953	penicillin-binding protein 1C
E5O11_RS13220	COG2373	Large extracellular alpha-helical protein
E5O11_RS13225	COG2897	thiosulfate sulfurtransferase activity
E5O11_RS13245	COG2975	iron-sulfur cluster assembly
E5O11_RS13250	COG0633	Ferredoxin
E5O11_RS13270	COG0822	iron-sulfur transferase activity
E5O11_RS13315	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E5O11_RS13325	COG3711	transcriptional antiterminator
E5O11_RS13330	COG2814	Major facilitator Superfamily
E5O11_RS13340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5O11_RS13340	COG1017	nitric oxide dioxygenase activity
E5O11_RS13345	COG3710	Transcriptional regulator
E5O11_RS13350	COG0531	amino acid
E5O11_RS13360	COG3104	oligopeptide transport
E5O11_RS13365	COG0347	Belongs to the P(II) protein family
E5O11_RS13370	COG2204	response regulator
E5O11_RS13375	COG3170	Tfp pilus assembly protein FimV
E5O11_RS13380	COG2205	protein histidine kinase activity
E5O11_RS13405	COG0560	Phosphoserine phosphatase
E5O11_RS13410	COG1263	PTS System
E5O11_RS13410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O11_RS13420	COG1737	Transcriptional regulator
E5O11_RS13425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E5O11_RS13430	COG2223	nitrite transmembrane transporter activity
E5O11_RS13435	COG0583	DNA-binding transcription factor activity
E5O11_RS13440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O11_RS13510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E5O11_RS13530	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O11_RS13640	COG4220	transposase activity
E5O11_RS13750	COG1484	DNA-dependent DNA replication
E5O11_RS13785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O11_RS13810	COG3086	response to oxidative stress
E5O11_RS13850	COG0513	Belongs to the DEAD box helicase family
E5O11_RS13855	COG0583	DNA-binding transcription factor activity
E5O11_RS13875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5O11_RS13880	COG3118	belongs to the thioredoxin family
E5O11_RS13885	COG3148	PFAM DTW domain containing protein
E5O11_RS13895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5O11_RS13900	COG5544	Lipoprotein
E5O11_RS13905	COG0477	Major facilitator Superfamily
E5O11_RS13935	COG0542	response to heat
E5O11_RS13950	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5O11_RS13955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E5O11_RS13965	COG1605	Chorismate mutase
E5O11_RS13965	COG0077	Prephenate dehydratase
E5O11_RS13975	COG0287	Prephenate dehydrogenase
E5O11_RS13975	COG1605	Chorismate mutase
E5O11_RS13990	COG2199	diguanylate cyclase activity
E5O11_RS14015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E5O11_RS14020	COG4137	Cytochrome C assembly protein
E5O11_RS14025	COG4536	flavin adenine dinucleotide binding
E5O11_RS14045	COG0497	DNA recombination
E5O11_RS14060	COG2867	negative regulation of translational initiation
E5O11_RS14085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O11_RS14095	COG0582	viral genome integration into host DNA
E5O11_RS14100	COG0582	viral genome integration into host DNA
E5O11_RS14130	COG4133	protoheme IX ABC transporter activity
E5O11_RS14145	COG3423	Transcriptional regulator
E5O11_RS14240	COG0640	Transcriptional regulator
E5O11_RS14255	COG0786	glutamate:sodium symporter activity
E5O11_RS14300	COG2819	hydrolase of the alpha beta superfamily
E5O11_RS14320	COG2990	Protein conserved in bacteria
E5O11_RS14335	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E5O11_RS14370	COG0579	oxidoreductase
E5O11_RS14375	COG1012	belongs to the aldehyde dehydrogenase family
E5O11_RS14380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E5O11_RS14385	COG1113	amino acid transport
E5O11_RS14390	COG1802	Transcriptional regulator
E5O11_RS14395	COG1652	LysM domain
E5O11_RS14405	COG0401	homolog of Blt101
E5O11_RS14410	COG0640	Transcriptional regulator
E5O11_RS14415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5O11_RS14445	COG4575	ribosome binding
E5O11_RS14455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5O11_RS14500	COG2814	Major facilitator Superfamily
E5O11_RS14505	COG1846	Transcriptional regulator
E5O11_RS14510	COG1566	PFAM secretion protein HlyD family protein
E5O11_RS14515	COG2814	Major facilitator Superfamily
E5O11_RS14535	COG1238	metal cluster binding
E5O11_RS14540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5O11_RS14570	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E5O11_RS14595	COG1546	Belongs to the CinA family
E5O11_RS14605	COG2951	lytic endotransglycosylase activity
E5O11_RS14610	COG3730	PTS system glucitol sorbitol-specific
E5O11_RS14615	COG3732	PTS system glucitol sorbitol-specific
E5O11_RS14625	COG1028	Short-chain dehydrogenase reductase Sdr
E5O11_RS14630	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS14635	COG1349	DNA-binding transcription factor activity
E5O11_RS14660	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E5O11_RS14665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O11_RS14675	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5O11_RS14685	COG3260	NADH ubiquinone oxidoreductase 20
E5O11_RS14690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5O11_RS14695	COG3261	NADH dehydrogenase
E5O11_RS14695	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E5O11_RS14700	COG0650	Formate hydrogenlyase subunit 4
E5O11_RS14705	COG0651	ATP synthesis coupled electron transport
E5O11_RS14710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O11_RS14725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E5O11_RS14730	COG0298	carbon dioxide binding
E5O11_RS14735	COG0409	Hydrogenase expression formation protein
E5O11_RS14740	COG0309	Hydrogenase expression formation protein (HypE)
E5O11_RS14760	COG1121	(ABC) transporter
E5O11_RS14765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5O11_RS14770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5O11_RS14945	COG2207	Transcriptional regulator
E5O11_RS15010	COG0477	Major facilitator Superfamily
E5O11_RS15020	COG2610	gluconate transmembrane transporter activity
E5O11_RS15025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5O11_RS15030	COG3622	Belongs to the hyi family
E5O11_RS15035	COG0235	Class ii aldolase
E5O11_RS15045	COG2084	Dehydrogenase
E5O11_RS15050	COG1349	DNA-binding transcription factor activity
E5O11_RS15060	COG0163	prenyltransferase activity
E5O11_RS15065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E5O11_RS15135	COG2234	aminopeptidase activity
E5O11_RS15140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O11_RS15145	COG1518	maintenance of DNA repeat elements
E5O11_RS15160	COG1857	crispr-associated protein
E5O11_RS15200	COG0720	synthase
E5O11_RS15205	COG0321	lipoyl(octanoyl) transferase activity
E5O11_RS15205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E5O11_RS15210	COG0602	queuosine metabolic process
E5O11_RS15225	COG3956	TIGRFAM MazG family protein
E5O11_RS15240	COG3609	addiction module antidote protein, CC2985 family
E5O11_RS15245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5O11_RS15255	COG4999	Histidine kinase
E5O11_RS15255	COG3437	response regulator, receiver
E5O11_RS15255	COG2205	protein histidine kinase activity
E5O11_RS15255	COG3850	Histidine kinase
E5O11_RS15260	COG1929	Belongs to the glycerate kinase type-1 family
E5O11_RS15265	COG4948	Mandelate Racemase Muconate Lactonizing
E5O11_RS15270	COG4948	Mandelate Racemase Muconate Lactonizing
E5O11_RS15275	COG2271	Major facilitator Superfamily
E5O11_RS15285	COG0716	FMN binding
E5O11_RS15295	COG3098	single-species biofilm formation
E5O11_RS15315	COG1611	Belongs to the LOG family
E5O11_RS15320	COG0814	amino acid
E5O11_RS15325	COG1760	l-serine dehydratase
E5O11_RS15335	COG1454	alcohol dehydrogenase
E5O11_RS15340	COG0235	Class ii aldolase
E5O11_RS15345	COG0738	Major facilitator superfamily
E5O11_RS15365	COG1349	DNA-binding transcription factor activity
E5O11_RS15375	COG2363	Small membrane protein
E5O11_RS15380	COG0583	DNA-binding transcription factor activity
E5O11_RS15390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E5O11_RS15395	COG2166	iron-sulfur cluster assembly
E5O11_RS15400	COG2962	Rard protein
E5O11_RS15405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E5O11_RS15410	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E5O11_RS15425	COG0860	N-Acetylmuramoyl-L-alanine amidase
E5O11_RS15435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E5O11_RS15440	COG1074	ATP-dependent DNA helicase activity
E5O11_RS15450	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E5O11_RS15455	COG4967	type IV pilus modification protein PilV
E5O11_RS15465	COG4795	General secretion pathway protein
E5O11_RS15470	COG2165	general secretion pathway protein
E5O11_RS15500	COG0861	Integral membrane protein TerC family
E5O11_RS15510	COG0667	Aldo Keto reductase
E5O11_RS15530	COG1609	Transcriptional regulator
E5O11_RS15540	COG0583	DNA-binding transcription factor activity
E5O11_RS15545	COG1794	racemase activity, acting on amino acids and derivatives
E5O11_RS15550	COG2814	Major facilitator Superfamily
E5O11_RS15555	COG1028	Short-chain dehydrogenase reductase Sdr
E5O11_RS15565	COG0183	Belongs to the thiolase family
E5O11_RS15580	COG0814	amino acid
E5O11_RS15615	COG3188	usher protein
E5O11_RS15665	COG4942	peptidase
E5O11_RS15720	COG1272	protein, Hemolysin III
E5O11_RS15730	COG2723	6-phospho-beta-galactosidase activity
E5O11_RS15760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5O11_RS15765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5O11_RS15770	COG0006	proline dipeptidase activity
E5O11_RS15790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E5O11_RS15795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E5O11_RS15810	COG2968	Membrane
E5O11_RS15820	COG0668	transmembrane transport
E5O11_RS15825	COG0191	fructose-bisphosphate aldolase activity
E5O11_RS15855	COG1122	ATPase activity
E5O11_RS15860	COG1122	ATPase activity
E5O11_RS15865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E5O11_RS15870	COG0501	Belongs to the peptidase M48B family
E5O11_RS15880	COG2267	carboxylic ester hydrolase activity
E5O11_RS15885	COG2731	YhcH YjgK YiaL family protein
E5O11_RS15890	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E5O11_RS15895	COG1063	alcohol dehydrogenase
E5O11_RS15900	COG0246	Mannitol dehydrogenase
E5O11_RS15910	COG2186	Transcriptional regulator
E5O11_RS15920	COG1166	arginine decarboxylase activity
E5O11_RS15940	COG2814	Major facilitator Superfamily
E5O11_RS15950	COG2356	endonuclease I
E5O11_RS15955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E5O11_RS15980	COG2805	Type II/IV secretion system protein
E5O11_RS15985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E5O11_RS15990	COG0762	integral membrane protein
E5O11_RS16005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E5O11_RS16015	COG0252	asparaginase activity
E5O11_RS16025	COG3171	Protein conserved in bacteria
E5O11_RS16050	COG2211	Major facilitator Superfamily
E5O11_RS16055	COG1982	Orn Lys Arg decarboxylase major
E5O11_RS16060	COG1811	Na channel or pump
E5O11_RS16075	COG0427	acetyl-CoA hydrolase
E5O11_RS16080	COG2030	dehydratase
E5O11_RS16085	COG2301	Belongs to the HpcH HpaI aldolase family
E5O11_RS16115	COG0531	amino acid
E5O11_RS16125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E5O11_RS16130	COG1012	belongs to the aldehyde dehydrogenase family
E5O11_RS16155	COG2271	Major facilitator Superfamily
E5O11_RS16165	COG0246	Mannitol dehydrogenase
E5O11_RS16180	COG0754	glutathionylspermidine amidase activity
E5O11_RS16185	COG0625	glutathione transferase activity
E5O11_RS16195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E5O11_RS16200	COG0298	carbon dioxide binding
E5O11_RS16210	COG1773	rubredoxin
E5O11_RS16215	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5O11_RS16220	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E5O11_RS16225	COG5557	Pfam Polysulphide reductase, NrfD
E5O11_RS16230	COG0437	4 iron, 4 sulfur cluster binding
E5O11_RS16235	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5O11_RS16245	COG0840	transmembrane signaling receptor activity
E5O11_RS16270	COG1028	Short-chain dehydrogenase reductase Sdr
E5O11_RS16275	COG0848	biopolymer transport protein
E5O11_RS16295	COG2207	Transcriptional regulator
E5O11_RS16300	COG1979	alcohol dehydrogenase
E5O11_RS16310	COG0471	metal ion transport
E5O11_RS16365	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5O11_RS16370	COG3111	PFAM Bacterial OB fold (BOF) protein
E5O11_RS16385	COG2249	NAD(P)H dehydrogenase (quinone) activity
E5O11_RS16390	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E5O11_RS16400	COG3150	esterase
E5O11_RS16405	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E5O11_RS16410	COG3151	Protein conserved in bacteria
E5O11_RS16415	COG0494	nUDIX hydrolase
E5O11_RS16430	COG0754	glutathionylspermidine amidase activity
E5O11_RS16435	COG3384	dioxygenase
E5O11_RS16475	COG1585	Membrane protein implicated in regulation of membrane protease activity
E5O11_RS16480	COG2268	Band 7 protein
E5O11_RS16500	COG3025	triphosphatase activity
E5O11_RS16505	COG4991	sh3 domain protein
E5O11_RS16520	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E5O11_RS16540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E5O11_RS16595	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O11_RS16690	COG4695	Portal protein
E5O11_RS16755	COG4974	Belongs to the 'phage' integrase family
E5O11_RS16765	COG2375	cellular response to nickel ion
E5O11_RS16770	COG1695	Transcriptional regulator
E5O11_RS16775	COG0840	transmembrane signaling receptor activity
E5O11_RS16780	COG0840	transmembrane signaling receptor activity
E5O11_RS16790	COG1902	pentaerythritol trinitrate reductase activity
E5O11_RS16790	COG0446	pyridine nucleotide-disulphide oxidoreductase
E5O11_RS16800	COG1451	nucleotide metabolic process
E5O11_RS16805	COG2949	membrane
E5O11_RS16810	COG0673	inositol 2-dehydrogenase activity
E5O11_RS16825	COG0586	Pfam SNARE associated Golgi protein
E5O11_RS16835	COG1422	Protein of unknown function (DUF1090)
E5O11_RS16840	COG4575	ribosome binding
E5O11_RS16845	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E5O11_RS16855	COG2259	Doxx family
E5O11_RS16860	COG0435	Glutathione S-transferase
E5O11_RS16865	COG3152	Membrane
E5O11_RS16870	COG0583	DNA-binding transcription factor activity
E5O11_RS16875	COG1741	Belongs to the pirin family
E5O11_RS16890	COG0814	amino acid
E5O11_RS16895	COG1760	l-serine dehydratase
E5O11_RS16900	COG1882	Formate acetyltransferase
E5O11_RS16920	COG0583	DNA-binding transcription factor activity
E5O11_RS16930	COG1929	Belongs to the glycerate kinase type-1 family
E5O11_RS16935	COG2084	Dehydrogenase
E5O11_RS16945	COG2721	sulfolactate sulfo-lyase activity
E5O11_RS16950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS16955	COG1349	DNA-binding transcription factor activity
E5O11_RS16965	COG1105	Belongs to the carbohydrate kinase PfkB family
E5O11_RS16970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O11_RS16970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS16970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O11_RS16985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS16990	COG3414	Phosphotransferase system galactitol-specific IIB component
E5O11_RS16995	COG3775	system Galactitol-specific IIC component
E5O11_RS17000	COG1063	alcohol dehydrogenase
E5O11_RS17010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E5O11_RS17030	COG2823	Periplasmic or secreted lipoprotein
E5O11_RS17035	COG0702	epimerase
E5O11_RS17040	COG0693	protein deglycase activity
E5O11_RS17055	COG3153	acetyltransferase
E5O11_RS17060	COG3154	lipid carrier protein
E5O11_RS17065	COG0826	peptidase U32
E5O11_RS17070	COG0826	peptidase U32
E5O11_RS17075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E5O11_RS17080	COG3034	peptidoglycan biosynthetic process
E5O11_RS17090	COG0814	amino acid
E5O11_RS17095	COG0513	Belongs to the DEAD box helicase family
E5O11_RS17165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E5O11_RS17175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E5O11_RS17190	COG1534	Rna-binding protein
E5O11_RS17200	COG2027	D-alanyl-D-alanine carboxypeptidase
E5O11_RS17210	COG0697	spore germination
E5O11_RS17225	COG0142	geranyltranstransferase activity
E5O11_RS17230	COG3423	Transcriptional regulator
E5O11_RS17240	COG5007	Belongs to the BolA IbaG family
E5O11_RS17245	COG3113	response to antibiotic
E5O11_RS17250	COG2854	intermembrane phospholipid transfer
E5O11_RS17255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E5O11_RS17260	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E5O11_RS17265	COG1127	ABC transporter
E5O11_RS17270	COG0530	calcium, potassium:sodium antiporter activity
E5O11_RS17285	COG3117	lipopolysaccharide transmembrane transporter activity
E5O11_RS17290	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E5O11_RS17295	COG1137	ATPase activity
E5O11_RS17320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS17325	COG0515	serine threonine protein kinase
E5O11_RS17335	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E5O11_RS17340	COG0784	Response regulator, receiver
E5O11_RS17340	COG5002	protein histidine kinase activity
E5O11_RS17340	COG2198	Histidine kinase
E5O11_RS17345	COG1242	4 iron, 4 sulfur cluster binding
E5O11_RS17350	COG0069	glutamate synthase activity
E5O11_RS17350	COG0067	glutamate synthase
E5O11_RS17350	COG0070	glutamate synthase
E5O11_RS17355	COG0493	'glutamate synthase
E5O11_RS17360	COG4804	nuclease activity
E5O11_RS17365	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E5O11_RS17370	COG0402	S-adenosylhomocysteine deaminase activity
E5O11_RS17375	COG2731	YhcH YjgK YiaL family protein
E5O11_RS17405	COG2969	positive regulation of protein catabolic process
E5O11_RS17410	COG0625	glutathione transferase activity
E5O11_RS17435	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E5O11_RS17440	COG3105	Protein conserved in bacteria
E5O11_RS17445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E5O11_RS17455	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
E5O11_RS17475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O11_RS17480	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O11_RS17485	COG0471	metal ion transport
E5O11_RS17495	COG2188	Transcriptional regulator
E5O11_RS17520	COG2732	(Barnase) inhibitor
E5O11_RS17540	COG0583	DNA-binding transcription factor activity
E5O11_RS17545	COG0312	modulator of DNA gyrase
E5O11_RS17550	COG3164	Protein of unknown function
E5O11_RS17565	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E5O11_RS17570	COG1792	Involved in formation and maintenance of cell shape
E5O11_RS17575	COG1077	Cell shape determining protein MreB Mrl
E5O11_RS17580	COG2200	EAL domain
E5O11_RS17580	COG2199	diguanylate cyclase activity
E5O11_RS17585	COG0604	alcohol dehydrogenase
E5O11_RS17600	COG0511	ligase activity, forming carbon-carbon bonds
E5O11_RS17605	COG0439	Biotin carboxylase
E5O11_RS17610	COG3924	membrane
E5O11_RS17615	COG4145	pantothenate transmembrane transporter activity
E5O11_RS17635	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E5O11_RS17650	COG1309	transcriptional regulator
E5O11_RS17655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O11_RS17660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5O11_RS17700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E5O11_RS17720	COG0551	DNA topoisomerase type I activity
E5O11_RS17730	COG0758	DNA mediated transformation
E5O11_RS17760	COG3036	rescue of stalled ribosome
E5O11_RS17765	COG0789	Transcriptional regulator
E5O11_RS17805	COG0201	protein transport
E5O11_RS17885	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E5O11_RS17910	COG0051	transcription antitermination factor activity, RNA binding
E5O11_RS17965	COG2964	Protein conserved in bacteria
E5O11_RS17975	COG0545	Peptidyl-prolyl cis-trans isomerase
E5O11_RS17985	COG1047	Peptidyl-prolyl cis-trans
E5O11_RS17990	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E5O11_RS18005	COG0488	(ABC) transporter
E5O11_RS18020	COG0429	hydrolase of the alpha beta-hydrolase fold
E5O11_RS18030	COG3954	Phosphoribulokinase
E5O11_RS18035	COG1765	OsmC-like protein
E5O11_RS18045	COG1289	transmembrane transporter activity
E5O11_RS18080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E5O11_RS18125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E5O11_RS18130	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E5O11_RS18135	COG3266	domain, Protein
E5O11_RS18150	COG4796	Type ii and iii secretion system protein
E5O11_RS18165	COG3166	PFAM Fimbrial assembly family protein
E5O11_RS18170	COG4972	Pilus assembly protein
E5O11_RS18175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E5O11_RS18180	COG0494	nUDIX hydrolase
E5O11_RS18190	COG1011	Hydrolase
E5O11_RS18195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E5O11_RS18205	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5O11_RS18230	COG2183	response to ionizing radiation
E5O11_RS18235	COG1918	ferrous iron import across plasma membrane
E5O11_RS18250	COG5464	transposase or invertase
E5O11_RS18270	COG2610	gluconate transmembrane transporter activity
E5O11_RS18275	COG1640	4-alpha-glucanotransferase
E5O11_RS18280	COG0058	SHG alpha-glucan phosphorylase activity
E5O11_RS18290	COG3041	Addiction module toxin RelE StbE family
E5O11_RS18295	COG3077	Addiction module antitoxin, RelB DinJ family
E5O11_RS18305	COG1690	Belongs to the RtcB family
E5O11_RS18320	COG4650	regulator
E5O11_RS18325	COG1349	DNA-binding transcription factor activity
E5O11_RS18340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E5O11_RS18355	COG0371	Dehydrogenase
E5O11_RS18365	COG0129	dihydroxy-acid dehydratase activity
E5O11_RS18370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E5O11_RS18375	COG1414	Transcriptional regulator
E5O11_RS18380	COG0058	SHG alpha-glucan phosphorylase activity
E5O11_RS18410	COG2095	MarC family integral membrane protein
E5O11_RS18415	COG2610	gluconate transmembrane transporter activity
E5O11_RS18420	COG3265	gluconokinase activity
E5O11_RS18425	COG1609	Transcriptional regulator
E5O11_RS18430	COG1741	Belongs to the pirin family
E5O11_RS18435	COG0673	inositol 2-dehydrogenase activity
E5O11_RS18440	COG1247	-acetyltransferase
E5O11_RS18445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS18460	COG1735	metal-dependent hydrolase with the TIM-barrel fold
E5O11_RS18465	COG0405	Gamma-glutamyltransferase
E5O11_RS18475	COG0584	glycerophosphoryl diester phosphodiesterase
E5O11_RS18555	COG2177	Part of the ABC transporter FtsEX involved in
E5O11_RS18560	COG2884	Cell division ATP-binding protein ftsE
E5O11_RS18565	COG0552	protein localization to endoplasmic reticulum
E5O11_RS18570	COG0742	ribosomal rna small subunit methyltransferase
E5O11_RS18575	COG3776	membrane
E5O11_RS18585	COG3714	YhhN family
E5O11_RS18605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E5O11_RS18620	COG0628	permease
E5O11_RS18635	COG0842	Transport permease protein
E5O11_RS18640	COG0842	Transport permease protein
E5O11_RS18640	COG1129	ABC transporter
E5O11_RS18645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O11_RS18650	COG2081	HI0933 family
E5O11_RS18655	COG0306	phosphate transporter
E5O11_RS18685	COG0671	phosphoesterase, PA-phosphatase related
E5O11_RS18690	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E5O11_RS18695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5O11_RS18705	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5O11_RS18710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS18715	COG2222	sugar isomerase
E5O11_RS18720	COG2188	Transcriptional regulator
E5O11_RS18740	COG2197	response regulator
E5O11_RS18745	COG0583	DNA-binding transcription factor activity
E5O11_RS18750	COG1295	ribonuclease BN
E5O11_RS18755	COG0477	Major facilitator Superfamily
E5O11_RS18760	COG2982	Protein involved in outer membrane biogenesis
E5O11_RS18765	COG2200	EAL domain
E5O11_RS18770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS18785	COG2200	EAL domain
E5O11_RS18785	COG2199	diguanylate cyclase activity
E5O11_RS18845	COG0814	amino acid
E5O11_RS18850	COG4608	Belongs to the ABC transporter superfamily
E5O11_RS18855	COG0444	Belongs to the ABC transporter superfamily
E5O11_RS18860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E5O11_RS18865	COG0601	transmembrane transport
E5O11_RS18870	COG0747	negative chemotaxis
E5O11_RS18930	COG5571	outer membrane autotransporter
E5O11_RS18935	COG2818	Glycosylase
E5O11_RS18940	COG0456	acetyltransferase
E5O11_RS18945	COG0243	molybdopterin cofactor binding
E5O11_RS18950	COG2885	chlorophyll binding
E5O11_RS18965	COG2944	sequence-specific DNA binding
E5O11_RS18970	COG1278	Cold shock
E5O11_RS18995	COG2801	Transposase and inactivated derivatives
E5O11_RS19020	COG3274	enterobacterial common antigen metabolic process
E5O11_RS19025	COG4682	membrane
E5O11_RS19030	COG1070	Carbohydrate kinase
E5O11_RS19040	COG1609	Transcriptional regulator
E5O11_RS19040	COG2207	Transcriptional regulator
E5O11_RS19045	COG2992	FlgJ-related protein
E5O11_RS19050	COG0366	Alpha amylase catalytic
E5O11_RS19055	COG3977	Valine--pyruvate aminotransferase
E5O11_RS19060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O11_RS19065	COG1414	Transcriptional regulator
E5O11_RS19075	COG2731	YhcH YjgK YiaL family protein
E5O11_RS19085	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E5O11_RS19090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E5O11_RS19095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E5O11_RS19100	COG1070	Carbohydrate kinase
E5O11_RS19105	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E5O11_RS19110	COG3623	hexulose-6-phosphate isomerase
E5O11_RS19115	COG0235	Class ii aldolase
E5O11_RS19130	COG1012	belongs to the aldehyde dehydrogenase family
E5O11_RS19135	COG1940	carbohydrate kinase activity
E5O11_RS19140	COG3276	selenocysteine insertion sequence binding
E5O11_RS19150	COG0625	glutathione transferase activity
E5O11_RS19155	COG2213	PTS system mannitol-specific
E5O11_RS19155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS19165	COG3722	fumarate hydratase activity
E5O11_RS19195	COG2186	Transcriptional regulator
E5O11_RS19205	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E5O11_RS19210	COG1609	Transcriptional regulator
E5O11_RS19220	COG2271	Major facilitator Superfamily
E5O11_RS19240	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E5O11_RS19245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5O11_RS19255	COG4942	peptidase
E5O11_RS19260	COG2861	carbohydrate metabolic process
E5O11_RS19265	COG1216	Glycosyl transferase, family 2
E5O11_RS19345	COG0438	transferase activity, transferring glycosyl groups
E5O11_RS19350	COG0859	PFAM glycosyl transferase family 9
E5O11_RS19355	COG1519	Transferase
E5O11_RS19385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E5O11_RS19410	COG1561	YicC-like family, N-terminal region
E5O11_RS19415	COG0583	DNA-binding transcription factor activity
E5O11_RS19425	COG2860	membrane
E5O11_RS19445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5O11_RS19450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5O11_RS19455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E5O11_RS19465	COG0786	glutamate:sodium symporter activity
E5O11_RS19470	COG2233	PERMEase
E5O11_RS19475	COG2982	Protein involved in outer membrane biogenesis
E5O11_RS19480	COG1501	Belongs to the glycosyl hydrolase 31 family
E5O11_RS19485	COG2211	Major facilitator Superfamily
E5O11_RS19505	COG0419	ATPase involved in DNA repair
E5O11_RS19530	COG2771	luxR family
E5O11_RS19545	COG3710	Transcriptional regulator
E5O11_RS19555	COG1335	isochorismatase
E5O11_RS19585	COG5464	transposase or invertase
E5O11_RS19600	COG3716	PTS system mannose fructose sorbose family IID component
E5O11_RS19605	COG3715	PTS system
E5O11_RS19610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS19610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O11_RS19630	COG2723	6-phospho-beta-galactosidase activity
E5O11_RS19665	COG3775	system Galactitol-specific IIC component
E5O11_RS19670	COG3414	Phosphotransferase system galactitol-specific IIB component
E5O11_RS19675	COG3711	transcriptional antiterminator
E5O11_RS19675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS19680	COG2188	Transcriptional regulator
E5O11_RS19715	COG0738	Major facilitator superfamily
E5O11_RS19725	COG1349	DNA-binding transcription factor activity
E5O11_RS19730	COG0440	acetolactate synthase activity
E5O11_RS19735	COG0028	Belongs to the TPP enzyme family
E5O11_RS19760	COG2814	Major facilitator Superfamily
E5O11_RS19770	COG0583	DNA-binding transcription factor activity
E5O11_RS19775	COG2610	gluconate transmembrane transporter activity
E5O11_RS19785	COG0641	radical SAM
E5O11_RS19795	COG2149	membrane
E5O11_RS19815	COG5645	(Lipo)protein
E5O11_RS19820	COG0823	Involved in the tonB-independent uptake of proteins
E5O11_RS19825	COG4235	cytochrome complex assembly
E5O11_RS19825	COG3088	subunit of a heme lyase
E5O11_RS19835	COG1138	Cytochrome C-type biogenesis protein
E5O11_RS19845	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O11_RS19850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O11_RS19855	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O11_RS19865	COG1858	cytochrome C peroxidase
E5O11_RS19880	COG3005	denitrification pathway
E5O11_RS19885	COG0745	RESPONSE REGULATOR receiver
E5O11_RS19890	COG1879	ABC-type sugar transport system periplasmic component
E5O11_RS19895	COG0784	Response regulator, receiver
E5O11_RS19895	COG2198	Histidine kinase
E5O11_RS19895	COG2205	protein histidine kinase activity
E5O11_RS19900	COG2271	Major facilitator Superfamily
E5O11_RS19910	COG0800	Aldolase
E5O11_RS19915	COG3734	2-keto-3-deoxy-galactonokinase
E5O11_RS19920	COG2186	Transcriptional regulator
E5O11_RS19925	COG0561	phosphatase activity
E5O11_RS19930	COG2271	Major facilitator Superfamily
E5O11_RS19935	COG4948	Mandelate Racemase Muconate Lactonizing
E5O11_RS20015	COG2091	lysine biosynthetic process via aminoadipic acid
E5O11_RS20020	COG0431	NADPH-dependent FMN reductase
E5O11_RS20025	COG2252	PERMEase
E5O11_RS20030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5O11_RS20035	COG0704	Plays a role in the regulation of phosphate uptake
E5O11_RS20045	COG0581	inorganic phosphate transmembrane transporter activity
E5O11_RS20050	COG0573	inorganic phosphate transmembrane transporter activity
E5O11_RS20055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E5O11_RS20060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O11_RS20060	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E5O11_RS20060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O11_RS20065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E5O11_RS20070	COG4533	DNA binding
E5O11_RS20130	COG3312	ion transport
E5O11_RS20145	COG0716	FMN binding
E5O11_RS20150	COG1522	sequence-specific DNA binding
E5O11_RS20185	COG1172	Belongs to the binding-protein-dependent transport system permease family
E5O11_RS20195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS20200	COG1609	Transcriptional regulator
E5O11_RS20205	COG0477	Major facilitator Superfamily
E5O11_RS20210	COG2186	Transcriptional regulator
E5O11_RS20270	COG3978	acetolactate synthase activity
E5O11_RS20320	COG3201	nicotinamide mononucleotide transporter
E5O11_RS20340	COG3118	belongs to the thioredoxin family
E5O11_RS20375	COG1088	dTDP-glucose 4,6-dehydratase activity
E5O11_RS20380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E5O11_RS20380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E5O11_RS20385	COG0456	acetyltransferase
E5O11_RS20390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E5O11_RS20395	COG2244	polysaccharide biosynthetic process
E5O11_RS20440	COG3071	HemY protein
E5O11_RS20445	COG2959	enzyme of heme biosynthesis
E5O11_RS20515	COG1011	Hydrolase
E5O11_RS20570	COG2267	carboxylic ester hydrolase activity
E5O11_RS20575	COG0561	phosphatase activity
E5O11_RS20600	COG0641	radical SAM
E5O11_RS20645	COG0805	protein transport
E5O11_RS20690	COG1739	Uncharacterized protein family UPF0029
E5O11_RS20730	COG1763	Mo-molybdopterin cofactor biosynthetic process
E5O11_RS20740	COG3084	Protein conserved in bacteria
E5O11_RS20755	COG0204	Acyl-transferase
E5O11_RS20810	COG0561	phosphatase activity
E5O11_RS20855	COG1501	Belongs to the glycosyl hydrolase 31 family
E5O11_RS20860	COG2017	converts alpha-aldose to the beta-anomer
E5O11_RS20880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS20885	COG1349	DNA-binding transcription factor activity
E5O11_RS20890	COG1011	Hydrolase
E5O11_RS20905	COG0456	acetyltransferase
E5O11_RS20910	COG5499	transcription regulator containing HTH domain
E5O11_RS20915	COG4680	protein conserved in bacteria
E5O11_RS20925	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
E5O11_RS20940	COG2864	formate dehydrogenase
E5O11_RS20945	COG0437	4 iron, 4 sulfur cluster binding
E5O11_RS20975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E5O11_RS20990	COG1454	alcohol dehydrogenase
E5O11_RS21035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E5O11_RS21050	COG2258	MOSC domain
E5O11_RS21060	COG2205	protein histidine kinase activity
E5O11_RS21065	COG0745	RESPONSE REGULATOR receiver
E5O11_RS21070	COG3678	ATP-independent chaperone mediated protein folding
E5O11_RS21095	COG2211	Major facilitator Superfamily
E5O11_RS21110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5O11_RS21120	COG2134	cdp-diacylglycerol pyrophosphatase
E5O11_RS21130	COG1070	Carbohydrate kinase
E5O11_RS21185	COG3152	Membrane
E5O11_RS21195	COG1494	fructose-1,6-bisphosphatase
E5O11_RS21205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E5O11_RS21220	COG1575	Belongs to the MenA family. Type 1 subfamily
E5O11_RS21235	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E5O11_RS21240	COG1609	Transcriptional regulator
E5O11_RS21245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E5O11_RS21270	COG0626	cystathionine gamma-synthase activity
E5O11_RS21275	COG0460	homoserine dehydrogenase
E5O11_RS21275	COG0527	aspartate kinase activity
E5O11_RS21280	COG0668	transmembrane transport
E5O11_RS21295	COG0737	Belongs to the 5'-nucleotidase family
E5O11_RS21310	COG3738	Protein conserved in bacteria
E5O11_RS21315	COG0371	Dehydrogenase
E5O11_RS21325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS21325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5O11_RS21325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS21330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O11_RS21335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O11_RS21340	COG1882	Formate acetyltransferase
E5O11_RS21345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5O11_RS21350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O11_RS21355	COG2207	Transcriptional regulator
E5O11_RS21390	COG0583	DNA-binding transcription factor activity
E5O11_RS21500	COG0250	Participates in transcription elongation, termination and antitermination
E5O11_RS21570	COG2104	thiamine diphosphate biosynthetic process
E5O11_RS21575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E5O11_RS21685	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E5O11_RS21730	COG3122	Protein conserved in bacteria
E5O11_RS21770	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O11_RS21800	COG2246	polysaccharide biosynthetic process
E5O11_RS21880	COG0527	aspartate kinase activity
E5O11_RS21905	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5O11_RS21965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E5O11_RS21975	COG0534	Mate efflux family protein
E5O11_RS21990	COG0735	belongs to the Fur family
E5O11_RS22040	COG2315	Protein conserved in bacteria
E5O11_RS22105	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5O11_RS22125	COG2252	PERMEase
E5O11_RS22130	COG0025	NhaP-type Na H and K H
E5O11_RS22135	COG0583	DNA-binding transcription factor activity
E5O11_RS22140	COG1380	Effector of murein hydrolase LrgA
E5O11_RS22145	COG1346	cytolysis
E5O11_RS22155	COG3162	membrane
E5O11_RS22170	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E5O11_RS22175	COG0437	4 iron, 4 sulfur cluster binding
E5O11_RS22180	COG3301	Polysulphide reductase, NrfD
E5O11_RS22185	COG1138	Cytochrome C-type biogenesis protein
E5O11_RS22190	COG4235	cytochrome complex assembly
E5O11_RS22195	COG1301	dicarboxylic acid transport
E5O11_RS22200	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E5O11_RS22220	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E5O11_RS22225	COG2824	Alkylphosphonate utilization operon protein PhnA
E5O11_RS22255	COG0531	amino acid
E5O11_RS22260	COG2207	Transcriptional regulator
E5O11_RS22265	COG1982	Orn Lys Arg decarboxylase major
E5O11_RS22270	COG2169	Transcriptional regulator
E5O11_RS22285	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O11_RS22285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O11_RS22290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5O11_RS22300	COG4565	transcriptional regulatory protein
E5O11_RS22305	COG3290	protein histidine kinase activity
E5O11_RS22310	COG0243	molybdopterin cofactor binding
E5O11_RS22315	COG0437	4 iron, 4 sulfur cluster binding
E5O11_RS22320	COG3302	dmso reductase anchor subunit
E5O11_RS22325	COG3381	protein complex oligomerization
E5O11_RS22350	COG2197	response regulator
E5O11_RS22385	COG0789	Transcriptional regulator
E5O11_RS22410	COG0305	Participates in initiation and elongation during chromosome replication
E5O11_RS22455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E5O11_RS22545	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E5O11_RS22735	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O11_RS22765	COG0739	heme binding
E5O11_RS22775	COG2132	Multicopper oxidase
E5O11_RS22780	COG3667	copper resistance
E5O11_RS22785	COG2372	response to copper ion
E5O11_RS22790	COG1276	copper resistance
E5O11_RS22795	COG0745	RESPONSE REGULATOR receiver
E5O11_RS22800	COG2205	protein histidine kinase activity
E5O11_RS22810	COG0210	DNA helicase
E5O11_RS22820	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
E5O11_RS22830	COG1309	transcriptional regulator
E5O11_RS22845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5O11_RS22850	COG1027	Aspartate ammonia-lyase
E5O11_RS22855	COG3030	protein affecting phage T7 exclusion by the F plasmid
E5O11_RS22860	COG0531	amino acid
E5O11_RS22900	COG5510	response to toxic substance
E5O11_RS22930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E5O11_RS22935	COG1053	succinate dehydrogenase
E5O11_RS22955	COG1511	domain protein
E5O11_RS22955	COG3264	Mechanosensitive ion channel
E5O11_RS22975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O11_RS23000	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E5O11_RS23000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E5O11_RS23005	COG0802	atpase or kinase
E5O11_RS23030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E5O11_RS23035	COG0330	HflC and HflK could
E5O11_RS23040	COG0330	HflC and HflK could
E5O11_RS23045	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E5O11_RS23060	COG0557	exoribonuclease II activity
E5O11_RS23070	COG3789	protein conserved in bacteria
E5O11_RS23090	COG3766	membrane
E5O11_RS23095	COG5463	Belongs to the UPF0441 family
E5O11_RS23100	COG0754	glutathionylspermidine amidase activity
E5O11_RS23105	COG1960	acyl-CoA dehydrogenase activity
E5O11_RS23115	COG3650	response to hydrogen peroxide
E5O11_RS23120	COG1073	alpha beta
E5O11_RS23190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E5O11_RS23205	COG3061	Opacity-associated protein A
E5O11_RS23210	COG0545	Peptidyl-prolyl cis-trans isomerase
E5O11_RS23215	COG1113	amino acid transport
E5O11_RS23225	COG0697	spore germination
E5O11_RS23245	COG1733	regulation of RNA biosynthetic process
E5O11_RS23260	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E5O11_RS23270	COG1253	flavin adenine dinucleotide binding
E5O11_RS23290	COG2105	PFAM AIG2 family protein
E5O11_RS23295	COG2271	Major facilitator Superfamily
E5O11_RS23300	COG3964	amidohydrolase
E5O11_RS23315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E5O11_RS23320	COG1737	Transcriptional regulator
E5O11_RS23320	COG0837	glucose binding
E5O11_RS23325	COG2814	Major facilitator Superfamily
E5O11_RS23325	COG0477	Major facilitator Superfamily
E5O11_RS23335	COG0477	Major facilitator Superfamily
E5O11_RS23335	COG2814	Major facilitator Superfamily
E5O11_RS23340	COG3718	enzyme involved in inositol metabolism
E5O11_RS23370	COG5520	Belongs to the glycosyl hydrolase 30 family
E5O11_RS23375	COG1082	Xylose isomerase domain protein TIM barrel
E5O11_RS23385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O11_RS23390	COG3962	Belongs to the TPP enzyme family
E5O11_RS23395	COG0673	inositol 2-dehydrogenase activity
E5O11_RS23400	COG2814	Major facilitator Superfamily
E5O11_RS23410	COG1082	Xylose isomerase domain protein TIM barrel
E5O11_RS23420	COG0312	modulator of DNA gyrase
E5O11_RS23455	COG3964	amidohydrolase
E5O11_RS23470	COG3711	transcriptional antiterminator
E5O11_RS23470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O11_RS23475	COG3077	Addiction module antitoxin, RelB DinJ family
E5O11_RS23480	COG2026	Addiction module toxin, RelE StbE family
E5O11_RS23495	COG0366	Alpha amylase catalytic
E5O11_RS23550	COG1438	arginine binding
E5O11_RS23555	COG1288	antiporter activity
E5O11_RS23575	COG2731	YhcH YjgK YiaL family protein
E5O11_RS23615	COG2927	DNA polymerase III (CHI subunit)
E5O11_RS23625	COG0795	lipopolysaccharide-transporting ATPase activity
E5O11_RS23630	COG0795	lipopolysaccharide-transporting ATPase activity
E5O11_RS23635	COG1609	Transcriptional regulator
E5O11_RS23640	COG2610	gluconate transmembrane transporter activity
E5O11_RS23645	COG1028	Short-chain dehydrogenase reductase Sdr
E5O11_RS23650	COG1063	alcohol dehydrogenase
E5O11_RS23655	COG3265	gluconokinase activity
E5O11_RS23660	COG1064	alcohol dehydrogenase
E5O11_RS23670	COG0582	viral genome integration into host DNA
E5O11_RS23675	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E5O11_RS23675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5O11_RS23700	COG4133	protoheme IX ABC transporter activity
E5O11_RS23735	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E5O11_RS23765	COG0412	Dienelactone hydrolase
E5O11_RS23770	COG2186	Transcriptional regulator
E5O11_RS23790	COG0583	DNA-binding transcription factor activity
E5O11_RS23795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5O11_RS23800	COG0700	Nucleoside recognition
E5O11_RS23805	COG3366	ferrous iron transmembrane transporter activity
E5O11_RS23810	COG0477	Major facilitator Superfamily
E5O11_RS23815	COG2733	membrane
E5O11_RS23825	COG5464	transposase or invertase
E5O11_RS23830	COG1012	belongs to the aldehyde dehydrogenase family
E5O11_RS23865	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
E5O11_RS23870	COG1715	Restriction endonuclease
E5O11_RS23885	COG0523	cobalamin synthesis protein
E5O11_RS23890	COG2879	small protein
E5O11_RS23895	COG1966	Carbon starvation protein
E5O11_RS23900	COG0840	transmembrane signaling receptor activity
E5O11_RS23915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O11_RS23920	COG3715	PTS system
E5O11_RS23925	COG3716	PTS system mannose fructose sorbose family IID component
E5O11_RS23930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E5O11_RS23950	COG1484	DNA-dependent DNA replication
E5O11_RS23965	COG2966	Psort location CytoplasmicMembrane, score
E5O11_RS23970	COG2197	response regulator
E5O11_RS23975	COG2197	response regulator
E5O11_RS23980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E5O11_RS23985	COG4114	ferric iron reductase
E5O11_RS23990	COG3706	GGDEF domain
E5O11_RS24020	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E5O11_RS24030	COG1011	Hydrolase
E5O11_RS24040	COG2823	Periplasmic or secreted lipoprotein
E5O11_RS24050	COG4667	esterase of the alpha-beta hydrolase superfamily
E5O11_RS24055	COG0084	hydrolase, TatD family'
E5O11_RS24060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5O11_RS24065	COG1328	CTP reductase activity
E5O11_RS24095	COG3188	usher protein
E5O11_RS24100	COG3121	Chaperone
E5O11_RS24105	COG3539	Fimbrial protein
E5O11_RS24120	COG3726	membrane protein affecting hemolysin expression
E5O11_RS24125	COG0560	Phosphoserine phosphatase
E5O11_RS24140	COG0488	(ABC) transporter
E5O11_RS24165	COG3708	Transcriptional regulator
E5O11_RS24165	COG2207	Transcriptional regulator
E5O11_RS24170	COG3045	CreA protein
E5O11_RS24175	COG0745	RESPONSE REGULATOR receiver
E5O11_RS24180	COG2205	protein histidine kinase activity
E5O11_RS24185	COG4452	Inner membrane protein CreD
E5O11_RS24205	COG3121	Chaperone
E5O11_RS24225	COG0745	RESPONSE REGULATOR receiver
E5O11_RS24235	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E5O11_RS24310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E5O11_RS24340	COG2948	multi-organism process
E5O11_RS24390	COG0250	Participates in transcription elongation, termination and antitermination
E5O11_RS24435	COG2026	Addiction module toxin, RelE StbE family
E5O11_RS24480	COG1192	Involved in chromosome partitioning