locus-tag	class	description
F4V19_RS00010	COG3047	cAMP biosynthetic process
F4V19_RS00010	COG2885	chlorophyll binding
F4V19_RS00165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F4V19_RS00180	COG0121	glutamine amidotransferase
F4V19_RS00185	COG3034	peptidoglycan biosynthetic process
F4V19_RS00195	COG1690	Belongs to the RtcB family
F4V19_RS00200	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F4V19_RS00205	COG2195	Cleaves the N-terminal amino acid of tripeptides
F4V19_RS00245	COG0582	viral genome integration into host DNA
F4V19_RS00270	COG2814	Major facilitator Superfamily
F4V19_RS00285	COG0179	Fumarylacetoacetate (FAA) hydrolase
F4V19_RS00320	COG3188	usher protein
F4V19_RS00325	COG3121	Chaperone
F4V19_RS00330	COG3539	Fimbrial protein
F4V19_RS00345	COG2200	EAL domain
F4V19_RS00400	COG0789	Transcriptional regulator
F4V19_RS00410	COG2814	Major facilitator Superfamily
F4V19_RS00430	COG1271	oxidase subunit
F4V19_RS00435	COG1294	oxidase, subunit
F4V19_RS00455	COG1280	lysine exporter protein (LysE YggA)
F4V19_RS00490	COG0113	porphobilinogen synthase activity
F4V19_RS00505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F4V19_RS00510	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F4V19_RS00555	COG3706	GGDEF domain
F4V19_RS00560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F4V19_RS00580	COG4126	flavin adenine dinucleotide binding
F4V19_RS00595	COG1940	carbohydrate kinase activity
F4V19_RS00600	COG2814	Major facilitator Superfamily
F4V19_RS00605	COG0419	ATPase involved in DNA repair
F4V19_RS00620	COG5002	protein histidine kinase activity
F4V19_RS00635	COG0366	Alpha amylase catalytic
F4V19_RS00640	COG0450	alkyl hydroperoxide reductase
F4V19_RS00660	COG1862	Preprotein translocase
F4V19_RS00670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F4V19_RS00705	COG4238	major outer membrane lipoprotein
F4V19_RS00715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F4V19_RS00715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F4V19_RS00730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F4V19_RS00735	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F4V19_RS00740	COG0667	Aldo Keto reductase
F4V19_RS00750	COG0142	geranyltranstransferase activity
F4V19_RS00785	COG2188	Transcriptional regulator
F4V19_RS00815	COG2814	Major facilitator Superfamily
F4V19_RS00835	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F4V19_RS00840	COG1845	cytochrome c oxidase, subunit III
F4V19_RS00845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F4V19_RS00850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F4V19_RS00855	COG2223	nitrite transmembrane transporter activity
F4V19_RS00860	COG3056	Lipoprotein
F4V19_RS00865	COG0271	Belongs to the BolA IbaG family
F4V19_RS00890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F4V19_RS00900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F4V19_RS00905	COG1555	photosystem II stabilization
F4V19_RS00910	COG0824	Thioesterase
F4V19_RS00920	COG4533	DNA binding
F4V19_RS00935	COG1522	sequence-specific DNA binding
F4V19_RS00940	COG1132	(ABC) transporter
F4V19_RS00945	COG1132	(ABC) transporter
F4V19_RS00950	COG0347	Belongs to the P(II) protein family
F4V19_RS00955	COG0004	ammonium transporteR
F4V19_RS00960	COG1946	Acyl-CoA thioesterase
F4V19_RS00965	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F4V19_RS00970	COG3695	enzyme binding
F4V19_RS00980	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F4V19_RS01000	COG0110	maltose O-acetyltransferase activity
F4V19_RS01015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F4V19_RS01020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F4V19_RS01025	COG1309	transcriptional regulator
F4V19_RS01030	COG3264	Mechanosensitive ion channel
F4V19_RS01030	COG1196	nuclear chromosome segregation
F4V19_RS01035	COG5464	transposase or invertase
F4V19_RS01045	COG3923	Primosomal replication protein n
F4V19_RS01050	COG2832	Protein of unknown function (DUF454)
F4V19_RS01095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F4V19_RS01100	COG4651	solute:proton antiporter activity
F4V19_RS01100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F4V19_RS01105	COG2223	nitrite transmembrane transporter activity
F4V19_RS01120	COG3735	TraB family
F4V19_RS01130	COG2217	Heavy metal translocating P-type atpase
F4V19_RS01140	COG1585	Membrane protein implicated in regulation of membrane protease activity
F4V19_RS01145	COG0330	HflC and HflK could
F4V19_RS01150	COG4619	ABC transporter
F4V19_RS01155	COG0390	transport system, permease component
F4V19_RS01160	COG3118	belongs to the thioredoxin family
F4V19_RS01165	COG0300	oxidoreductase activity
F4V19_RS01170	COG2755	lipolytic protein G-D-S-L family
F4V19_RS01175	COG4181	ATPase activity
F4V19_RS01180	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F4V19_RS01190	COG1464	Belongs to the NlpA lipoprotein family
F4V19_RS01225	COG3960	tartronate-semialdehyde synthase activity
F4V19_RS01230	COG3622	Belongs to the hyi family
F4V19_RS01235	COG2084	Dehydrogenase
F4V19_RS01255	COG2233	PERMEase
F4V19_RS01260	COG1929	Belongs to the glycerate kinase type-1 family
F4V19_RS01265	COG3257	ureidoglycine aminohydrolase activity
F4V19_RS01270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F4V19_RS01275	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F4V19_RS01280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F4V19_RS01285	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F4V19_RS01295	COG0549	Belongs to the carbamate kinase family
F4V19_RS01300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F4V19_RS01305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F4V19_RS01315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F4V19_RS01335	COG1988	membrane-bound metal-dependent
F4V19_RS01340	COG2501	S4 domain
F4V19_RS01430	COG2246	polysaccharide biosynthetic process
F4V19_RS01435	COG0463	Glycosyl transferase, family 2
F4V19_RS01460	COG0463	Glycosyl transferase, family 2
F4V19_RS01465	COG2246	polysaccharide biosynthetic process
F4V19_RS01475	COG5002	protein histidine kinase activity
F4V19_RS01485	COG2207	Transcriptional regulator
F4V19_RS01490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F4V19_RS01500	COG3059	membrane
F4V19_RS01510	COG1113	amino acid transport
F4V19_RS01515	COG0668	transmembrane transport
F4V19_RS01530	COG2315	Protein conserved in bacteria
F4V19_RS01555	COG2977	Belongs to the P-Pant transferase superfamily
F4V19_RS01560	COG4771	TonB-dependent receptor
F4V19_RS01565	COG2382	esterase
F4V19_RS01570	COG3251	PFAM MbtH domain protein
F4V19_RS01575	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F4V19_RS01575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F4V19_RS01580	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
F4V19_RS01585	COG1120	ATPase activity
F4V19_RS01590	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F4V19_RS01595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F4V19_RS01605	COG4592	Periplasmic binding protein
F4V19_RS01610	COG1169	isochorismate synthase
F4V19_RS01615	COG1021	2,3-dihydroxybenzoate-AMP ligase
F4V19_RS01620	COG1535	isochorismatase
F4V19_RS01620	COG3433	isochorismatase activity
F4V19_RS01625	COG1028	Short-chain dehydrogenase reductase Sdr
F4V19_RS01635	COG1966	Carbon starvation protein
F4V19_RS01640	COG2879	small protein
F4V19_RS01645	COG0371	Dehydrogenase
F4V19_RS01650	COG0436	Aminotransferase
F4V19_RS01655	COG1475	DNA binding
F4V19_RS01660	COG3969	phosphoadenosine phosphosulfate
F4V19_RS01665	COG0583	DNA-binding transcription factor activity
F4V19_RS01690	COG0243	molybdopterin cofactor binding
F4V19_RS01710	COG1063	alcohol dehydrogenase
F4V19_RS01715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F4V19_RS01720	COG3719	Belongs to the RNase T2 family
F4V19_RS01725	COG0471	metal ion transport
F4V19_RS01740	COG3051	citrate lyase alpha subunit
F4V19_RS01745	COG2301	Belongs to the HpcH HpaI aldolase family
F4V19_RS01755	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
F4V19_RS01760	COG3290	protein histidine kinase activity
F4V19_RS01765	COG4565	transcriptional regulatory protein
F4V19_RS01770	COG3069	C4-dicarboxylate transmembrane transporter activity
F4V19_RS01790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F4V19_RS01805	COG0583	DNA-binding transcription factor activity
F4V19_RS01820	COG1686	Belongs to the peptidase S11 family
F4V19_RS01830	COG0772	Belongs to the SEDS family
F4V19_RS01835	COG0768	penicillin binding
F4V19_RS01845	COG0799	negative regulation of ribosome biogenesis
F4V19_RS01865	COG1466	dna polymerase III delta subunit
F4V19_RS01895	COG3829	transcription factor binding
F4V19_RS01895	COG3290	protein histidine kinase activity
F4V19_RS01900	COG2888	peptidyl-tyrosine sulfation
F4V19_RS01915	COG2214	Heat shock protein DnaJ domain protein
F4V19_RS01925	COG2214	Heat shock protein DnaJ domain protein
F4V19_RS01930	COG0443	Heat shock 70 kDa protein
F4V19_RS01945	COG1126	abc transporter atp-binding protein
F4V19_RS01950	COG0765	amino acid transport
F4V19_RS01955	COG0765	amino acid transport
F4V19_RS01980	COG1702	phosphate starvation-inducible protein PhoH
F4V19_RS01990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F4V19_RS02035	COG0367	asparagine synthase
F4V19_RS02040	COG0647	UMP catabolic process
F4V19_RS02045	COG1940	carbohydrate kinase activity
F4V19_RS02045	COG1846	Transcriptional regulator
F4V19_RS02050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F4V19_RS02090	COG1053	succinate dehydrogenase
F4V19_RS02095	COG0583	DNA-binding transcription factor activity
F4V19_RS02100	COG0735	belongs to the Fur family
F4V19_RS02115	COG0596	Alpha beta hydrolase
F4V19_RS02125	COG0033	Phosphoglucomutase
F4V19_RS02135	COG0531	amino acid
F4V19_RS02140	COG1982	Orn Lys Arg decarboxylase major
F4V19_RS02150	COG0745	RESPONSE REGULATOR receiver
F4V19_RS02155	COG2205	protein histidine kinase activity
F4V19_RS02170	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F4V19_RS02200	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F4V19_RS02205	COG1984	allophanate hydrolase subunit 2
F4V19_RS02220	COG3180	Ammonia monooxygenase
F4V19_RS02235	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F4V19_RS02250	COG0567	Dehydrogenase, E1 component
F4V19_RS02255	COG0508	dehydrogenase complex catalyzes the overall conversion of
F4V19_RS02265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F4V19_RS02270	COG1271	oxidase subunit
F4V19_RS02275	COG1294	oxidase, subunit
F4V19_RS02280	COG4890	Cyd operon protein YbgT
F4V19_RS02285	COG3790	cyd operon protein YbgE
F4V19_RS02290	COG0824	Thioesterase
F4V19_RS02295	COG0811	peptide transport
F4V19_RS02300	COG0848	biopolymer transport protein
F4V19_RS02305	COG3064	Membrane
F4V19_RS02315	COG2885	chlorophyll binding
F4V19_RS02320	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F4V19_RS02355	COG1230	cation diffusion facilitator family transporter
F4V19_RS02365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F4V19_RS02370	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F4V19_RS02370	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F4V19_RS02380	COG0583	DNA-binding transcription factor activity
F4V19_RS02385	COG0583	DNA-binding transcription factor activity
F4V19_RS02390	COG0490	domain, Protein
F4V19_RS02390	COG0471	metal ion transport
F4V19_RS02400	COG5016	pyruvate
F4V19_RS02400	COG0511	ligase activity, forming carbon-carbon bonds
F4V19_RS02415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F4V19_RS02420	COG1120	ATPase activity
F4V19_RS02430	COG2017	converts alpha-aldose to the beta-anomer
F4V19_RS02455	COG1119	ATPase activity
F4V19_RS02460	COG3585	molybdate ion transport
F4V19_RS02460	COG2005	Transcriptional regulator
F4V19_RS02470	COG0725	ABC transporter, periplasmic molybdate-binding protein
F4V19_RS02475	COG4149	molybdate abc transporter
F4V19_RS02485	COG0561	phosphatase activity
F4V19_RS02495	COG4677	pectinesterase activity
F4V19_RS02525	COG1881	PFAM PEBP family protein
F4V19_RS02585	COG0521	Mo-molybdopterin cofactor biosynthetic process
F4V19_RS02605	COG0670	Belongs to the BI1 family
F4V19_RS02625	COG0392	lysyltransferase activity
F4V19_RS02630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F4V19_RS02635	COG3568	Endonuclease Exonuclease Phosphatase
F4V19_RS02645	COG0842	Transport permease protein
F4V19_RS02650	COG0842	Transport permease protein
F4V19_RS02655	COG1131	(ABC) transporter
F4V19_RS02665	COG1309	transcriptional regulator
F4V19_RS02680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F4V19_RS02690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F4V19_RS02700	COG0668	transmembrane transport
F4V19_RS02705	COG1126	abc transporter atp-binding protein
F4V19_RS02710	COG0765	amino acid transport
F4V19_RS02715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F4V19_RS02730	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F4V19_RS02735	COG2194	sulfuric ester hydrolase activity
F4V19_RS02750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F4V19_RS02755	COG1376	ErfK ybiS ycfS ynhG family protein
F4V19_RS02760	COG0488	(ABC) transporter
F4V19_RS02770	COG0561	phosphatase activity
F4V19_RS02775	COG1882	Formate acetyltransferase
F4V19_RS02780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F4V19_RS02805	COG0747	negative chemotaxis
F4V19_RS02830	COG2301	Belongs to the HpcH HpaI aldolase family
F4V19_RS02850	COG1960	acyl-CoA dehydrogenase activity
F4V19_RS02860	COG0583	DNA-binding transcription factor activity
F4V19_RS02865	COG2610	gluconate transmembrane transporter activity
F4V19_RS02875	COG2133	pyrroloquinoline quinone binding
F4V19_RS02880	COG0625	glutathione transferase activity
F4V19_RS02885	COG1686	Belongs to the peptidase S11 family
F4V19_RS02890	COG1349	DNA-binding transcription factor activity
F4V19_RS02895	COG0671	phosphoesterase, PA-phosphatase related
F4V19_RS02900	COG2814	Major facilitator Superfamily
F4V19_RS02905	COG0561	phosphatase activity
F4V19_RS02910	COG0738	Major facilitator superfamily
F4V19_RS02915	COG3226	Transcriptional regulator
F4V19_RS02960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F4V19_RS02965	COG3842	ATPase activity
F4V19_RS02970	COG1176	ABC-type spermidine putrescine transport system, permease component I
F4V19_RS02975	COG1177	transmembrane transport
F4V19_RS03005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F4V19_RS03010	COG4160	amino acid transport
F4V19_RS03015	COG4215	(ABC) transporter
F4V19_RS03020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F4V19_RS03025	COG1126	abc transporter atp-binding protein
F4V19_RS03040	COG3023	N-Acetylmuramoyl-L-alanine amidase
F4V19_RS03045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F4V19_RS03050	COG0702	epimerase
F4V19_RS03055	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F4V19_RS03060	COG0028	Belongs to the TPP enzyme family
F4V19_RS03065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F4V19_RS03075	COG2431	L-lysine efflux transmembrane transporter activity
F4V19_RS03080	COG3593	DNA synthesis involved in DNA repair
F4V19_RS03085	COG2990	Protein conserved in bacteria
F4V19_RS03090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F4V19_RS03095	COG1136	(ABC) transporter
F4V19_RS03095	COG0577	efflux transmembrane transporter activity
F4V19_RS03100	COG1278	Cold shock
F4V19_RS03110	COG0542	response to heat
F4V19_RS03145	COG1335	isochorismatase
F4V19_RS03155	COG0583	DNA-binding transcription factor activity
F4V19_RS03175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F4V19_RS03180	COG4988	ABC transporter
F4V19_RS03185	COG0492	ferredoxin-NADP+ reductase activity
F4V19_RS03205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F4V19_RS03215	COG0243	molybdopterin cofactor binding
F4V19_RS03220	COG0437	4 iron, 4 sulfur cluster binding
F4V19_RS03225	COG3302	dmso reductase anchor subunit
F4V19_RS03235	COG0531	amino acid
F4V19_RS03240	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F4V19_RS03255	COG1882	Formate acetyltransferase
F4V19_RS03260	COG2116	formate transmembrane transporter activity
F4V19_RS03265	COG1944	ATP diphosphatase activity
F4V19_RS03270	COG2323	membrane
F4V19_RS03285	COG0501	Belongs to the peptidase M48B family
F4V19_RS03295	COG0539	negative regulation of cytoplasmic translation
F4V19_RS03310	COG2333	competence protein COMEC
F4V19_RS03310	COG0658	competence protein
F4V19_RS03325	COG3214	Protein conserved in bacteria
F4V19_RS03340	COG3173	Aminoglycoside phosphotransferase
F4V19_RS03345	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F4V19_RS03350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F4V19_RS03360	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F4V19_RS03370	COG2989	Protein conserved in bacteria
F4V19_RS03375	COG3108	Peptidase M15
F4V19_RS03380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F4V19_RS03390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F4V19_RS03400	COG1522	sequence-specific DNA binding
F4V19_RS03415	COG1115	amino acid carrier protein
F4V19_RS03425	COG0308	aminopeptidase N
F4V19_RS03440	COG3217	Mosc domain protein beta barrel domain protein
F4V19_RS03440	COG0633	Ferredoxin
F4V19_RS03450	COG0488	(ABC) transporter
F4V19_RS03455	COG2995	paraquat-inducible protein a
F4V19_RS03460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F4V19_RS03460	COG3008	intermembrane lipid transfer
F4V19_RS03465	COG3009	Protein conserved in bacteria
F4V19_RS03470	COG3130	regulation of translation
F4V19_RS03480	COG1067	ATP-dependent peptidase activity
F4V19_RS03500	COG3070	regulator of competence-specific genes
F4V19_RS03505	COG1289	transmembrane transporter activity
F4V19_RS03510	COG3304	Inner membrane component domain
F4V19_RS03515	COG0210	DNA helicase
F4V19_RS03530	COG1832	CoA-binding protein
F4V19_RS03545	COG1881	PFAM PEBP family protein
F4V19_RS03565	COG0670	Belongs to the BI1 family
F4V19_RS03610	COG2205	protein histidine kinase activity
F4V19_RS03615	COG0745	RESPONSE REGULATOR receiver
F4V19_RS03630	COG2368	4-hydroxyphenylacetate
F4V19_RS03635	COG1846	Transcriptional regulator
F4V19_RS03645	COG1012	belongs to the aldehyde dehydrogenase family
F4V19_RS03650	COG3384	dioxygenase
F4V19_RS03660	COG3971	2-oxopent-4-enoate hydratase activity
F4V19_RS03705	COG4232	protein-disulfide reductase activity
F4V19_RS03710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F4V19_RS03710	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F4V19_RS03715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F4V19_RS03735	COG3729	General stress protein
F4V19_RS03740	COG1309	transcriptional regulator
F4V19_RS03760	COG1702	phosphate starvation-inducible protein PhoH
F4V19_RS03765	COG1737	Transcriptional regulator
F4V19_RS03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F4V19_RS03790	COG2814	Major facilitator Superfamily
F4V19_RS03795	COG0673	inositol 2-dehydrogenase activity
F4V19_RS03825	COG3381	protein complex oligomerization
F4V19_RS03880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F4V19_RS03885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F4V19_RS03900	COG5645	(Lipo)protein
F4V19_RS03915	COG1560	Kdo2-lipid A biosynthetic process
F4V19_RS03930	COG3038	cytochrome b561
F4V19_RS03965	COG2999	glutathione oxidoreductase activity
F4V19_RS03975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F4V19_RS04065	COG1530	ribonuclease E activity
F4V19_RS04125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F4V19_RS04130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F4V19_RS04135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F4V19_RS04145	COG0470	DNA polymerase III
F4V19_RS04150	COG0084	hydrolase, TatD family'
F4V19_RS04160	COG4773	Receptor
F4V19_RS04165	COG0537	adenosine 5'-monophosphoramidase activity
F4V19_RS04170	COG5633	Lipoprotein
F4V19_RS04195	COG1252	NADH dehydrogenase
F4V19_RS04200	COG3134	Outer membrane lipoprotein
F4V19_RS04205	COG1309	transcriptional regulator
F4V19_RS04220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F4V19_RS04225	COG4591	ABC-type transport system involved in lipoprotein release permease component
F4V19_RS04230	COG1136	(ABC) transporter
F4V19_RS04235	COG4591	ABC-type transport system involved in lipoprotein release permease component
F4V19_RS04255	COG1177	transmembrane transport
F4V19_RS04285	COG2850	peptidyl-arginine hydroxylation
F4V19_RS04300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F4V19_RS04330	COG0538	isocitrate dehydrogenase activity
F4V19_RS04405	COG0071	Belongs to the small heat shock protein (HSP20) family
F4V19_RS04415	COG3038	cytochrome b561
F4V19_RS04445	COG1124	(ABC) transporter
F4V19_RS04450	COG0668	transmembrane transport
F4V19_RS04465	COG3443	Belongs to the bacterial solute-binding protein 9 family
F4V19_RS04480	COG0789	Transcriptional regulator
F4V19_RS04495	COG1605	Chorismate mutase
F4V19_RS04505	COG3615	Tellurite resistance protein tehB
F4V19_RS04525	COG2261	transglycosylase associated protein
F4V19_RS04535	COG3042	response to heat
F4V19_RS04545	COG3189	MarR family transcriptional regulator
F4V19_RS04550	COG2807	transmembrane transport
F4V19_RS04555	COG2207	Transcriptional regulator
F4V19_RS04570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F4V19_RS04575	COG2199	diguanylate cyclase activity
F4V19_RS04585	COG2766	serine protein kinase
F4V19_RS04590	COG3713	MltA-interacting MipA family protein
F4V19_RS04595	COG0641	radical SAM
F4V19_RS04600	COG0656	L-ascorbic acid biosynthetic process
F4V19_RS04620	COG3139	Protein of unknown function (DUF1315)
F4V19_RS04625	COG1335	isochorismatase
F4V19_RS04630	COG0252	asparaginase activity
F4V19_RS04635	COG0616	signal peptide processing
F4V19_RS04640	COG0778	Nitroreductase
F4V19_RS04665	COG0494	nUDIX hydrolase
F4V19_RS04700	COG3678	ATP-independent chaperone mediated protein folding
F4V19_RS04715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F4V19_RS04720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F4V19_RS04725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F4V19_RS04730	COG1447	Phosphotransferase system cellobiose-specific component IIA
F4V19_RS04735	COG1917	Cupin 2, conserved barrel domain protein
F4V19_RS04735	COG2169	Transcriptional regulator
F4V19_RS04740	COG1486	melibiose metabolic process
F4V19_RS04750	COG0753	catalase activity
F4V19_RS04760	COG1823	symporter activity
F4V19_RS04765	COG1988	membrane-bound metal-dependent
F4V19_RS04770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F4V19_RS04780	COG3001	Fructosamine kinase
F4V19_RS04790	COG1105	Belongs to the carbohydrate kinase PfkB family
F4V19_RS04795	COG3137	Salt-induced outer membrane protein
F4V19_RS04940	COG0305	Participates in initiation and elongation during chromosome replication
F4V19_RS05000	COG0484	heat shock protein binding
F4V19_RS05030	COG4626	Terminase
F4V19_RS05030	COG1802	Transcriptional regulator
F4V19_RS05035	COG4695	Portal protein
F4V19_RS05245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F4V19_RS05265	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS05265	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS05350	COG4695	Portal protein
F4V19_RS05420	COG4974	Belongs to the 'phage' integrase family
F4V19_RS05440	COG0386	Belongs to the glutathione peroxidase family
F4V19_RS05450	COG0791	NLP P60 protein
F4V19_RS05465	COG4256	Hemin uptake protein
F4V19_RS05480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F4V19_RS05480	COG0574	Belongs to the PEP-utilizing enzyme family
F4V19_RS05485	COG0318	PFAM AMP-dependent synthetase and ligase
F4V19_RS05490	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F4V19_RS05495	COG0644	oxidoreductase
F4V19_RS05500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F4V19_RS05505	COG2086	electron transfer activity
F4V19_RS05510	COG2207	Transcriptional regulator
F4V19_RS05510	COG1917	Cupin 2, conserved barrel domain protein
F4V19_RS05515	COG1960	acyl-CoA dehydrogenase activity
F4V19_RS05520	COG4670	ketone body catabolic process
F4V19_RS05535	COG2271	Major facilitator Superfamily
F4V19_RS05540	COG0738	Major facilitator superfamily
F4V19_RS05555	COG0628	permease
F4V19_RS05560	COG0247	lactate metabolic process
F4V19_RS05560	COG0277	FAD linked oxidase domain protein
F4V19_RS05565	COG2050	protein possibly involved in aromatic compounds catabolism
F4V19_RS05575	COG1823	symporter activity
F4V19_RS05580	COG0316	Belongs to the HesB IscA family
F4V19_RS05585	COG0719	Fe-S assembly protein
F4V19_RS05590	COG0396	ATPase activity
F4V19_RS05595	COG0719	Fe-S assembly protein
F4V19_RS05610	COG1376	ErfK ybiS ycfS ynhG family protein
F4V19_RS05615	COG4238	major outer membrane lipoprotein
F4V19_RS05635	COG0531	amino acid
F4V19_RS05640	COG2267	carboxylic ester hydrolase activity
F4V19_RS05650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F4V19_RS05685	COG3272	Protein of unknown function (DUF1722)
F4V19_RS05690	COG0789	Transcriptional regulator
F4V19_RS05870	COG0307	riboflavin synthase, alpha
F4V19_RS05875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F4V19_RS05880	COG2814	Major facilitator Superfamily
F4V19_RS05885	COG0583	DNA-binding transcription factor activity
F4V19_RS05905	COG0791	NLP P60 protein
F4V19_RS05910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F4V19_RS05930	COG1902	pentaerythritol trinitrate reductase activity
F4V19_RS05935	COG1309	transcriptional regulator
F4V19_RS05940	COG3313	Fe-S protein
F4V19_RS05945	COG4989	oxidoreductase activity
F4V19_RS05960	COG1566	PFAM secretion protein HlyD family protein
F4V19_RS05985	COG3895	Periplasmic Protein
F4V19_RS06005	COG0625	glutathione transferase activity
F4V19_RS06015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F4V19_RS06065	COG0673	inositol 2-dehydrogenase activity
F4V19_RS06085	COG5339	Protein conserved in bacteria
F4V19_RS06110	COG2205	protein histidine kinase activity
F4V19_RS06115	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F4V19_RS06120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F4V19_RS06130	COG0745	RESPONSE REGULATOR receiver
F4V19_RS06135	COG3136	membrane protein required for alginate biosynthesis
F4V19_RS06140	COG0531	amino acid
F4V19_RS06150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F4V19_RS06155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F4V19_RS06160	COG0628	permease
F4V19_RS06180	COG3591	Belongs to the peptidase S1B family
F4V19_RS06190	COG2814	Major facilitator Superfamily
F4V19_RS06195	COG0583	DNA-binding transcription factor activity
F4V19_RS06200	COG1940	carbohydrate kinase activity
F4V19_RS06240	COG3302	dmso reductase anchor subunit
F4V19_RS06245	COG0437	4 iron, 4 sulfur cluster binding
F4V19_RS06250	COG0243	molybdopterin cofactor binding
F4V19_RS06255	COG0243	molybdopterin cofactor binding
F4V19_RS06270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F4V19_RS06290	COG1063	alcohol dehydrogenase
F4V19_RS06295	COG0477	Major facilitator Superfamily
F4V19_RS06300	COG0246	Mannitol dehydrogenase
F4V19_RS06310	COG1802	Transcriptional regulator
F4V19_RS06315	COG4221	oxidoreductase activity
F4V19_RS06330	COG3729	General stress protein
F4V19_RS06335	COG1546	Belongs to the CinA family
F4V19_RS06340	COG3111	PFAM Bacterial OB fold (BOF) protein
F4V19_RS06350	COG2814	Major facilitator Superfamily
F4V19_RS06385	COG0583	DNA-binding transcription factor activity
F4V19_RS06390	COG1012	belongs to the aldehyde dehydrogenase family
F4V19_RS06405	COG3781	membrane
F4V19_RS06430	COG1773	rubredoxin
F4V19_RS06455	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
F4V19_RS06460	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
F4V19_RS06470	COG2186	Transcriptional regulator
F4V19_RS06475	COG1063	alcohol dehydrogenase
F4V19_RS06480	COG2271	Major facilitator Superfamily
F4V19_RS06505	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F4V19_RS06510	COG0251	oxidation-reduction process
F4V19_RS06685	COG2801	Transposase and inactivated derivatives
F4V19_RS06705	COG1609	Transcriptional regulator
F4V19_RS06710	COG1757	Na H antiporter
F4V19_RS06715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F4V19_RS06730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F4V19_RS06745	COG1764	response to oxidative stress
F4V19_RS06765	COG1064	alcohol dehydrogenase
F4V19_RS06770	COG2864	formate dehydrogenase
F4V19_RS06775	COG0437	4 iron, 4 sulfur cluster binding
F4V19_RS06815	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F4V19_RS06820	COG1140	nitrate reductase beta subunit
F4V19_RS06825	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F4V19_RS06830	COG2181	nitrate reductase activity
F4V19_RS06870	COG4772	TonB-dependent receptor
F4V19_RS06875	COG1802	Transcriptional regulator
F4V19_RS06880	COG2130	NADP-dependent
F4V19_RS06890	COG3238	Protein conserved in bacteria
F4V19_RS06930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F4V19_RS06935	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
F4V19_RS06960	COG0826	peptidase U32
F4V19_RS06965	COG1396	sequence-specific DNA binding
F4V19_RS06970	COG3135	benzoate transporter
F4V19_RS06980	COG0500	methyltransferase
F4V19_RS06985	COG1275	C4-dicarboxylate transporter malic acid transport protein
F4V19_RS06990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F4V19_RS06995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F4V19_RS07005	COG3414	Phosphotransferase system galactitol-specific IIB component
F4V19_RS07010	COG3775	system Galactitol-specific IIC component
F4V19_RS07015	COG0434	BtpA family
F4V19_RS07020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS07025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F4V19_RS07030	COG1349	DNA-binding transcription factor activity
F4V19_RS07040	COG1304	FMN binding
F4V19_RS07045	COG2353	YceI-like domain
F4V19_RS07055	COG2272	Belongs to the type-B carboxylesterase lipase family
F4V19_RS07060	COG5383	Protein conserved in bacteria
F4V19_RS07065	COG0583	DNA-binding transcription factor activity
F4V19_RS07070	COG0840	transmembrane signaling receptor activity
F4V19_RS07110	COG0765	amino acid transport
F4V19_RS07120	COG0765	amino acid transport
F4V19_RS07130	COG0500	methyltransferase
F4V19_RS07135	COG3038	cytochrome b561
F4V19_RS07140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F4V19_RS07145	COG1643	Atp-dependent helicase
F4V19_RS07160	COG3784	Protein of unknown function (DUF1318)
F4V19_RS07170	COG2911	Protein conserved in bacteria
F4V19_RS07175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F4V19_RS07180	COG3187	Heat shock protein
F4V19_RS07185	COG3042	response to heat
F4V19_RS07195	COG1013	pyruvate-flavodoxin oxidoreductase activity
F4V19_RS07195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F4V19_RS07195	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
F4V19_RS07195	COG0674	pyruvate-flavodoxin oxidoreductase activity
F4V19_RS07205	COG2076	Multidrug Resistance protein
F4V19_RS07225	COG0513	Belongs to the DEAD box helicase family
F4V19_RS07240	COG0840	transmembrane signaling receptor activity
F4V19_RS07245	COG2840	Smr protein MutS2
F4V19_RS07265	COG3182	Iron-regulated membrane protein
F4V19_RS07270	COG0668	transmembrane transport
F4V19_RS07290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F4V19_RS07325	COG1309	transcriptional regulator
F4V19_RS07330	COG1028	Short-chain dehydrogenase reductase Sdr
F4V19_RS07335	COG0656	L-ascorbic acid biosynthetic process
F4V19_RS07340	COG0583	DNA-binding transcription factor activity
F4V19_RS07350	COG4166	transmembrane transport
F4V19_RS07355	COG2866	Carboxypeptidase
F4V19_RS07360	COG4948	Mandelate Racemase Muconate Lactonizing
F4V19_RS07380	COG3106	COG3106 Predicted ATPase
F4V19_RS07385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F4V19_RS07395	COG1983	PspC domain protein
F4V19_RS07405	COG1842	Phage shock protein A
F4V19_RS07410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F4V19_RS07465	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F4V19_RS07465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F4V19_RS07475	COG5001	Diguanylate cyclase
F4V19_RS07485	COG1349	DNA-binding transcription factor activity
F4V19_RS07505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F4V19_RS07510	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F4V19_RS07515	COG0671	phosphoesterase, PA-phosphatase related
F4V19_RS07555	COG0616	signal peptide processing
F4V19_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
F4V19_RS07575	COG0009	L-threonylcarbamoyladenylate synthase
F4V19_RS07615	COG3729	General stress protein
F4V19_RS07620	COG3685	Protein conserved in bacteria
F4V19_RS07625	COG3685	Protein conserved in bacteria
F4V19_RS07630	COG3546	catalase activity
F4V19_RS07635	COG3047	cAMP biosynthetic process
F4V19_RS07640	COG0727	PFAM Uncharacterised protein family (UPF0153)
F4V19_RS07665	COG2350	Protein conserved in bacteria
F4V19_RS07685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F4V19_RS07720	COG1012	belongs to the aldehyde dehydrogenase family
F4V19_RS07720	COG1454	alcohol dehydrogenase
F4V19_RS07735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F4V19_RS07740	COG0745	RESPONSE REGULATOR receiver
F4V19_RS07745	COG1752	Esterase of the alpha-beta hydrolase superfamily
F4V19_RS07755	COG0788	formyltetrahydrofolate deformylase activity
F4V19_RS07790	COG2181	nitrate reductase activity
F4V19_RS07795	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F4V19_RS07800	COG1140	nitrate reductase beta subunit
F4V19_RS07805	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F4V19_RS07810	COG2223	nitrite transmembrane transporter activity
F4V19_RS07815	COG3850	Histidine kinase
F4V19_RS07820	COG2197	response regulator
F4V19_RS07825	COG4932	domain protein
F4V19_RS07830	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F4V19_RS07835	COG4572	Cation transport regulator
F4V19_RS07840	COG0387	Pfam Sodium calcium exchanger
F4V19_RS07890	COG0659	secondary active sulfate transmembrane transporter activity
F4V19_RS07905	COG0012	GTP binding
F4V19_RS07915	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
F4V19_RS07925	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
F4V19_RS07930	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F4V19_RS07935	COG1999	signal sequence binding
F4V19_RS07940	COG1773	rubredoxin
F4V19_RS07945	COG1271	oxidase subunit
F4V19_RS07950	COG1294	oxidase, subunit
F4V19_RS07960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F4V19_RS07985	COG1619	proteins homologs of microcin C7 resistance protein MccF
F4V19_RS08005	COG2719	SpoVR family
F4V19_RS08045	COG0179	Fumarylacetoacetate (FAA) hydrolase
F4V19_RS08060	COG2894	cell division
F4V19_RS08070	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F4V19_RS08080	COG3065	identical protein binding
F4V19_RS08090	COG1199	ATP-dependent helicase activity
F4V19_RS08095	COG0251	oxidation-reduction process
F4V19_RS08115	COG1760	l-serine dehydratase
F4V19_RS08120	COG2200	EAL domain
F4V19_RS08125	COG1253	flavin adenine dinucleotide binding
F4V19_RS08130	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS08130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F4V19_RS08135	COG3715	PTS system
F4V19_RS08140	COG3716	PTS system mannose fructose sorbose family IID component
F4V19_RS08155	COG2226	methyltransferase
F4V19_RS08160	COG0768	penicillin binding
F4V19_RS08190	COG1414	Transcriptional regulator
F4V19_RS08195	COG2814	Major facilitator Superfamily
F4V19_RS08215	COG1956	GAF domain-containing protein
F4V19_RS08220	COG2995	paraquat-inducible protein a
F4V19_RS08225	COG3008	intermembrane lipid transfer
F4V19_RS08260	COG5562	phage envelope protein
F4V19_RS08270	COG0454	-acetyltransferase
F4V19_RS08280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F4V19_RS08290	COG3328	transposase activity
F4V19_RS08380	COG0582	viral genome integration into host DNA
F4V19_RS08410	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS08450	COG0741	lytic transglycosylase activity
F4V19_RS08450	COG1388	LysM domain
F4V19_RS08525	COG1783	phage Terminase large subunit
F4V19_RS08615	COG3756	Protein conserved in bacteria
F4V19_RS08655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F4V19_RS08660	COG3723	Recombinational DNA repair protein, rece pathway
F4V19_RS08690	COG1276	copper resistance
F4V19_RS08695	COG2372	response to copper ion
F4V19_RS08705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F4V19_RS08710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F4V19_RS08715	COG1770	oligopeptidase
F4V19_RS08720	COG2979	Protein of unknown function (DUF533)
F4V19_RS08730	COG3141	response to X-ray
F4V19_RS08740	COG0800	Aldolase
F4V19_RS08745	COG0129	dihydroxy-acid dehydratase activity
F4V19_RS08750	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F4V19_RS08755	COG1737	Transcriptional regulator
F4V19_RS08765	COG1560	Kdo2-lipid A biosynthetic process
F4V19_RS08770	COG0739	heme binding
F4V19_RS08775	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F4V19_RS08785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F4V19_RS08820	COG0494	nUDIX hydrolase
F4V19_RS08830	COG1335	isochorismatase
F4V19_RS08835	COG1801	Protein of unknown function DUF72
F4V19_RS08840	COG3788	relative of glutathione S-transferase, MAPEG superfamily
F4V19_RS08860	COG3102	Protein conserved in bacteria
F4V19_RS08875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F4V19_RS08980	COG1528	Iron-storage protein
F4V19_RS08995	COG1528	Iron-storage protein
F4V19_RS09005	COG0814	amino acid
F4V19_RS09010	COG3318	Belongs to the UPF0149 family
F4V19_RS09010	COG3012	SEC-C Motif Domain Protein
F4V19_RS09055	COG2197	response regulator
F4V19_RS09070	COG2197	response regulator
F4V19_RS09075	COG1126	abc transporter atp-binding protein
F4V19_RS09080	COG0765	amino acid transport
F4V19_RS09090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F4V19_RS09145	COG0425	Belongs to the sulfur carrier protein TusA family
F4V19_RS09250	COG5475	Uncharacterized small protein (DUF2158)
F4V19_RS09255	COG2354	Protein conserved in bacteria
F4V19_RS09260	COG0697	spore germination
F4V19_RS09265	COG3727	T/G mismatch-specific endonuclease activity
F4V19_RS09270	COG0270	DNA (cytosine-5-)-methyltransferase activity
F4V19_RS09275	COG1418	mRNA catabolic process
F4V19_RS09285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F4V19_RS09330	COG0582	viral genome integration into host DNA
F4V19_RS09375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F4V19_RS09425	COG0534	Mate efflux family protein
F4V19_RS09590	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
F4V19_RS09605	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
F4V19_RS09620	COG1012	belongs to the aldehyde dehydrogenase family
F4V19_RS09620	COG1454	alcohol dehydrogenase
F4V19_RS09625	COG4656	Part of a membrane complex involved in electron transport
F4V19_RS09660	COG1289	transmembrane transporter activity
F4V19_RS09700	COG2925	Exonuclease
F4V19_RS09705	COG0531	amino acid
F4V19_RS09715	COG0583	DNA-binding transcription factor activity
F4V19_RS09720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F4V19_RS09805	COG0438	transferase activity, transferring glycosyl groups
F4V19_RS09835	COG2327	Polysaccharide pyruvyl transferase
F4V19_RS09840	COG2244	polysaccharide biosynthetic process
F4V19_RS09845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F4V19_RS09860	COG0297	glycogen (starch) synthase activity
F4V19_RS09870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F4V19_RS09875	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
F4V19_RS09880	COG0110	maltose O-acetyltransferase activity
F4V19_RS09885	COG1216	Glycosyl transferase, family 2
F4V19_RS09895	COG0438	transferase activity, transferring glycosyl groups
F4V19_RS09900	COG1045	serine acetyltransferase
F4V19_RS09905	COG0463	Glycosyl transferase, family 2
F4V19_RS09925	COG1253	flavin adenine dinucleotide binding
F4V19_RS09930	COG2982	Protein involved in outer membrane biogenesis
F4V19_RS09945	COG3447	MASE1 domain protein
F4V19_RS09945	COG5001	Diguanylate cyclase
F4V19_RS09945	COG5002	protein histidine kinase activity
F4V19_RS09950	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F4V19_RS09955	COG0443	Heat shock 70 kDa protein
F4V19_RS09985	COG2205	protein histidine kinase activity
F4V19_RS09990	COG0745	RESPONSE REGULATOR receiver
F4V19_RS10040	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F4V19_RS10065	COG3209	COG3209 Rhs family protein
F4V19_RS10095	COG0826	peptidase U32
F4V19_RS10130	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS10225	COG4695	Portal protein
F4V19_RS10265	COG4974	Belongs to the 'phage' integrase family
F4V19_RS10295	COG1830	Aldolase
F4V19_RS10300	COG2211	Major facilitator Superfamily
F4V19_RS10305	COG1397	ADP-ribosylglycohydrolase
F4V19_RS10310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F4V19_RS10315	COG2188	Transcriptional regulator
F4V19_RS10335	COG5455	response to cobalt ion
F4V19_RS10340	COG3539	Fimbrial protein
F4V19_RS10345	COG3188	usher protein
F4V19_RS10350	COG3121	Chaperone
F4V19_RS10375	COG4808	Protein conserved in bacteria
F4V19_RS10385	COG4807	Protein conserved in bacteria
F4V19_RS10395	COG3275	phosphorelay sensor kinase activity
F4V19_RS10410	COG1174	glycine betaine transport
F4V19_RS10415	COG1125	glycine betaine transport
F4V19_RS10420	COG1174	glycine betaine transport
F4V19_RS10425	COG1732	Glycine betaine
F4V19_RS10435	COG0277	FAD linked oxidase domain protein
F4V19_RS10440	COG1686	Belongs to the peptidase S11 family
F4V19_RS10450	COG0586	Pfam SNARE associated Golgi protein
F4V19_RS10455	COG1028	Short-chain dehydrogenase reductase Sdr
F4V19_RS10460	COG1538	Outer membrane efflux protein
F4V19_RS10475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F4V19_RS10480	COG0625	glutathione transferase activity
F4V19_RS10495	COG2271	Major facilitator Superfamily
F4V19_RS10510	COG1346	cytolysis
F4V19_RS10520	COG2949	membrane
F4V19_RS10620	COG2890	protein-(glutamine-N5) methyltransferase activity
F4V19_RS10680	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F4V19_RS10765	COG1192	Involved in chromosome partitioning
F4V19_RS10860	COG0210	DNA helicase
F4V19_RS11000	COG4245	von Willebrand factor, type A
F4V19_RS11005	COG4245	von Willebrand factor, type A
F4V19_RS11035	COG1358	cellular component organization or biogenesis
F4V19_RS11165	COG3550	peptidyl-serine autophosphorylation
F4V19_RS11225	COG5001	Diguanylate cyclase
F4V19_RS11225	COG3300	MHYT domain
F4V19_RS11385	COG2801	Transposase and inactivated derivatives
F4V19_RS11390	COG3547	Transposase (IS116 IS110 IS902 family)
F4V19_RS11400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F4V19_RS11410	COG3077	Addiction module antitoxin, RelB DinJ family
F4V19_RS11415	COG2026	Addiction module toxin, RelE StbE family
F4V19_RS11570	COG3157	Type VI secretion system effector, Hcp
F4V19_RS11585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F4V19_RS11605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F4V19_RS11605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F4V19_RS11625	COG3039	Transposase
F4V19_RS11660	COG2801	Transposase and inactivated derivatives
F4V19_RS11675	COG2801	Transposase and inactivated derivatives
F4V19_RS11690	COG2801	Transposase and inactivated derivatives
F4V19_RS11695	COG0431	NADPH-dependent FMN reductase
F4V19_RS11700	COG0640	Transcriptional regulator
F4V19_RS11705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F4V19_RS11710	COG1393	Belongs to the ArsC family
F4V19_RS11715	COG0589	response to stress
F4V19_RS11720	COG0659	secondary active sulfate transmembrane transporter activity
F4V19_RS11810	COG2205	protein histidine kinase activity
F4V19_RS11820	COG2194	sulfuric ester hydrolase activity
F4V19_RS11870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F4V19_RS11900	COG1357	PFAM Pentapeptide repeats (8 copies)
F4V19_RS12085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F4V19_RS12225	COG2084	Dehydrogenase
F4V19_RS12235	COG1349	DNA-binding transcription factor activity
F4V19_RS12265	COG2311	Membrane
F4V19_RS12285	COG1760	l-serine dehydratase
F4V19_RS12290	COG0560	Phosphoserine phosphatase
F4V19_RS12295	COG2271	Major facilitator Superfamily
F4V19_RS12300	COG4771	TonB-dependent receptor
F4V19_RS12305	COG0833	amino acid
F4V19_RS12310	COG0583	DNA-binding transcription factor activity
F4V19_RS12315	COG2855	membrane
F4V19_RS12325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F4V19_RS12325	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F4V19_RS12325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F4V19_RS12330	COG1105	Belongs to the carbohydrate kinase PfkB family
F4V19_RS12365	COG0523	cobalamin synthesis protein
F4V19_RS12370	COG0671	phosphoesterase, PA-phosphatase related
F4V19_RS12375	COG0791	NLP P60 protein
F4V19_RS12380	COG2200	EAL domain
F4V19_RS12385	COG4166	transmembrane transport
F4V19_RS12390	COG4174	ABC transporter (Permease)
F4V19_RS12395	COG4239	(ABC) transporter, permease
F4V19_RS12400	COG4172	Belongs to the ABC transporter superfamily
F4V19_RS12410	COG2814	Major facilitator Superfamily
F4V19_RS12420	COG1061	Type III restriction enzyme res subunit
F4V19_RS12475	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS12490	COG2197	response regulator
F4V19_RS12495	COG4235	cytochrome complex assembly
F4V19_RS12495	COG3088	subunit of a heme lyase
F4V19_RS12505	COG1138	Cytochrome C-type biogenesis protein
F4V19_RS12515	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F4V19_RS12520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F4V19_RS12525	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F4V19_RS12535	COG3005	denitrification pathway
F4V19_RS12540	COG3043	anaerobic respiration
F4V19_RS12545	COG0348	domain, Protein
F4V19_RS12550	COG0437	4 iron, 4 sulfur cluster binding
F4V19_RS12560	COG3062	negative regulation of establishment of protein localization
F4V19_RS12565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F4V19_RS12565	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
F4V19_RS12575	COG4615	Cyclic peptide transporter
F4V19_RS12600	COG0642	Histidine kinase
F4V19_RS12600	COG2198	Histidine kinase
F4V19_RS12620	COG4948	Mandelate Racemase Muconate Lactonizing
F4V19_RS12650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F4V19_RS12655	COG2814	Major facilitator Superfamily
F4V19_RS12660	COG0583	DNA-binding transcription factor activity
F4V19_RS12665	COG0584	glycerophosphoryl diester phosphodiesterase
F4V19_RS12670	COG2271	Major facilitator Superfamily
F4V19_RS12675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F4V19_RS12685	COG0247	lactate metabolic process
F4V19_RS12705	COG2271	Major facilitator Superfamily
F4V19_RS12715	COG1414	Transcriptional regulator
F4V19_RS12805	COG1169	isochorismate synthase
F4V19_RS12810	COG4575	ribosome binding
F4V19_RS12815	COG2153	protein acetylation
F4V19_RS12825	COG0835	chemotaxis
F4V19_RS12825	COG0784	Response regulator, receiver
F4V19_RS12835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F4V19_RS12850	COG0839	Belongs to the complex I subunit 6 family
F4V19_RS12900	COG0583	DNA-binding transcription factor activity
F4V19_RS12905	COG0436	Aminotransferase
F4V19_RS12915	COG0490	domain, Protein
F4V19_RS12915	COG0471	metal ion transport
F4V19_RS12920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F4V19_RS12945	COG1288	antiporter activity
F4V19_RS12950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F4V19_RS12955	COG3959	Transketolase, thiamine diphosphate binding domain
F4V19_RS12960	COG3037	sugar-specific permease SgaT UlaA
F4V19_RS12970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS12975	COG1609	Transcriptional regulator
F4V19_RS12985	COG0622	Phosphoesterase
F4V19_RS12990	COG0625	glutathione transferase activity
F4V19_RS12995	COG0625	glutathione transferase activity
F4V19_RS13000	COG1090	epimerase
F4V19_RS13035	COG0833	amino acid
F4V19_RS13040	COG3457	Alanine racemase
F4V19_RS13045	COG0531	amino acid
F4V19_RS13060	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F4V19_RS13065	COG1286	toxin biosynthetic process
F4V19_RS13070	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F4V19_RS13075	COG0285	dihydrofolate synthase activity
F4V19_RS13085	COG0586	Pfam SNARE associated Golgi protein
F4V19_RS13095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F4V19_RS13120	COG3423	Transcriptional regulator
F4V19_RS13140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F4V19_RS13155	COG3101	peptidyl-lysine hydroxylation
F4V19_RS13160	COG0730	response to heat
F4V19_RS13185	COG2062	phosphohistidine phosphatase, SixA
F4V19_RS13200	COG3691	Protein conserved in bacteria
F4V19_RS13215	COG2116	formate transmembrane transporter activity
F4V19_RS13255	COG1560	Kdo2-lipid A biosynthetic process
F4V19_RS13265	COG0436	Aminotransferase
F4V19_RS13280	COG3961	Belongs to the TPP enzyme family
F4V19_RS13285	COG0667	Aldo Keto reductase
F4V19_RS13300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F4V19_RS13305	COG2199	diguanylate cyclase activity
F4V19_RS13305	COG2200	EAL domain
F4V19_RS13320	COG3415	Transposase
F4V19_RS13325	COG3415	Transposase
F4V19_RS13355	COG0583	DNA-binding transcription factor activity
F4V19_RS13365	COG2211	Major facilitator Superfamily
F4V19_RS13370	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F4V19_RS13380	COG0583	DNA-binding transcription factor activity
F4V19_RS13385	COG0385	Bile acid
F4V19_RS13390	COG3530	Putative quorum-sensing-regulated virulence factor
F4V19_RS13415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS13470	COG4208	sulfate ABC transporter
F4V19_RS13490	COG2837	iron assimilation
F4V19_RS13625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F4V19_RS13635	COG5342	invasion associated locus B
F4V19_RS13650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F4V19_RS13650	COG0493	'glutamate synthase
F4V19_RS13655	COG3850	Histidine kinase
F4V19_RS13660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F4V19_RS13670	COG1393	Belongs to the ArsC family
F4V19_RS13690	COG2321	neutral zinc metallopeptidase
F4V19_RS13700	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F4V19_RS13710	COG2716	regulation of RNA biosynthetic process
F4V19_RS13715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F4V19_RS13720	COG1929	Belongs to the glycerate kinase type-1 family
F4V19_RS13725	COG0628	permease
F4V19_RS13735	COG1393	Belongs to the ArsC family
F4V19_RS13745	COG2233	PERMEase
F4V19_RS13765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F4V19_RS13815	COG0517	IMP dehydrogenase activity
F4V19_RS13815	COG0516	GMP reductase activity
F4V19_RS13855	COG1645	bacterial-type flagellum-dependent swarming motility
F4V19_RS13870	COG2976	Protein conserved in bacteria
F4V19_RS13910	COG0437	4 iron, 4 sulfur cluster binding
F4V19_RS13915	COG0243	molybdopterin cofactor binding
F4V19_RS13920	COG4953	penicillin-binding protein 1C
F4V19_RS13930	COG2897	thiosulfate sulfurtransferase activity
F4V19_RS13950	COG2975	iron-sulfur cluster assembly
F4V19_RS13955	COG0633	Ferredoxin
F4V19_RS13975	COG0822	iron-sulfur transferase activity
F4V19_RS14020	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F4V19_RS14030	COG3711	transcriptional antiterminator
F4V19_RS14035	COG2814	Major facilitator Superfamily
F4V19_RS14045	COG1017	nitric oxide dioxygenase activity
F4V19_RS14045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F4V19_RS14050	COG3710	Transcriptional regulator
F4V19_RS14055	COG0531	amino acid
F4V19_RS14065	COG3104	oligopeptide transport
F4V19_RS14070	COG0347	Belongs to the P(II) protein family
F4V19_RS14075	COG2204	response regulator
F4V19_RS14080	COG3170	Tfp pilus assembly protein FimV
F4V19_RS14085	COG2205	protein histidine kinase activity
F4V19_RS14110	COG0560	Phosphoserine phosphatase
F4V19_RS14115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F4V19_RS14115	COG1263	PTS System
F4V19_RS14125	COG1737	Transcriptional regulator
F4V19_RS14130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F4V19_RS14135	COG2223	nitrite transmembrane transporter activity
F4V19_RS14140	COG0583	DNA-binding transcription factor activity
F4V19_RS14145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F4V19_RS14185	COG3086	response to oxidative stress
F4V19_RS14215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F4V19_RS14225	COG0513	Belongs to the DEAD box helicase family
F4V19_RS14230	COG0583	DNA-binding transcription factor activity
F4V19_RS14250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F4V19_RS14255	COG3118	belongs to the thioredoxin family
F4V19_RS14260	COG3148	PFAM DTW domain containing protein
F4V19_RS14270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F4V19_RS14275	COG5544	Lipoprotein
F4V19_RS14280	COG0477	Major facilitator Superfamily
F4V19_RS14310	COG0542	response to heat
F4V19_RS14325	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F4V19_RS14330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F4V19_RS14340	COG1605	Chorismate mutase
F4V19_RS14340	COG0077	Prephenate dehydratase
F4V19_RS14350	COG0287	Prephenate dehydrogenase
F4V19_RS14350	COG1605	Chorismate mutase
F4V19_RS14365	COG2199	diguanylate cyclase activity
F4V19_RS14390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F4V19_RS14395	COG4137	Cytochrome C assembly protein
F4V19_RS14400	COG4536	flavin adenine dinucleotide binding
F4V19_RS14420	COG0497	DNA recombination
F4V19_RS14435	COG2867	negative regulation of translational initiation
F4V19_RS14460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F4V19_RS14515	COG2819	hydrolase of the alpha beta superfamily
F4V19_RS14535	COG2990	Protein conserved in bacteria
F4V19_RS14550	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
F4V19_RS14585	COG0579	oxidoreductase
F4V19_RS14590	COG1012	belongs to the aldehyde dehydrogenase family
F4V19_RS14595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F4V19_RS14600	COG1113	amino acid transport
F4V19_RS14605	COG1802	Transcriptional regulator
F4V19_RS14610	COG1652	LysM domain
F4V19_RS14620	COG0401	homolog of Blt101
F4V19_RS14625	COG0640	Transcriptional regulator
F4V19_RS14630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F4V19_RS14655	COG4575	ribosome binding
F4V19_RS14665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F4V19_RS14710	COG2814	Major facilitator Superfamily
F4V19_RS14715	COG1846	Transcriptional regulator
F4V19_RS14720	COG1566	PFAM secretion protein HlyD family protein
F4V19_RS14745	COG1238	metal cluster binding
F4V19_RS14750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F4V19_RS14780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F4V19_RS14805	COG1546	Belongs to the CinA family
F4V19_RS14815	COG2951	lytic endotransglycosylase activity
F4V19_RS14820	COG3730	PTS system glucitol sorbitol-specific
F4V19_RS14825	COG3732	PTS system glucitol sorbitol-specific
F4V19_RS14835	COG1028	Short-chain dehydrogenase reductase Sdr
F4V19_RS14840	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS14845	COG1349	DNA-binding transcription factor activity
F4V19_RS14850	COG0517	IMP dehydrogenase activity
F4V19_RS14850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F4V19_RS14870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
F4V19_RS14875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F4V19_RS14885	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F4V19_RS14895	COG3260	NADH ubiquinone oxidoreductase 20
F4V19_RS14900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F4V19_RS14905	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
F4V19_RS14905	COG3261	NADH dehydrogenase
F4V19_RS14910	COG0650	Formate hydrogenlyase subunit 4
F4V19_RS14915	COG0651	ATP synthesis coupled electron transport
F4V19_RS14920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F4V19_RS14935	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F4V19_RS14940	COG0298	carbon dioxide binding
F4V19_RS14945	COG0409	Hydrogenase expression formation protein
F4V19_RS14950	COG0309	Hydrogenase expression formation protein (HypE)
F4V19_RS14970	COG1121	(ABC) transporter
F4V19_RS14975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F4V19_RS14980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F4V19_RS15065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F4V19_RS15155	COG2207	Transcriptional regulator
F4V19_RS15220	COG0477	Major facilitator Superfamily
F4V19_RS15230	COG2610	gluconate transmembrane transporter activity
F4V19_RS15235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F4V19_RS15240	COG3622	Belongs to the hyi family
F4V19_RS15245	COG0235	Class ii aldolase
F4V19_RS15255	COG2084	Dehydrogenase
F4V19_RS15260	COG1349	DNA-binding transcription factor activity
F4V19_RS15270	COG0163	prenyltransferase activity
F4V19_RS15275	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F4V19_RS15345	COG2234	aminopeptidase activity
F4V19_RS15350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F4V19_RS15355	COG1518	maintenance of DNA repeat elements
F4V19_RS15370	COG1857	crispr-associated protein
F4V19_RS15385	COG1203	CRISPR-associated helicase, Cas3
F4V19_RS15410	COG0720	synthase
F4V19_RS15415	COG0321	lipoyl(octanoyl) transferase activity
F4V19_RS15415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F4V19_RS15420	COG0602	queuosine metabolic process
F4V19_RS15435	COG3956	TIGRFAM MazG family protein
F4V19_RS15440	COG3539	Fimbrial protein
F4V19_RS15445	COG3188	usher protein
F4V19_RS15450	COG3121	Chaperone
F4V19_RS15455	COG3539	Fimbrial protein
F4V19_RS15490	COG3609	addiction module antidote protein, CC2985 family
F4V19_RS15495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F4V19_RS15505	COG4999	Histidine kinase
F4V19_RS15505	COG3437	response regulator, receiver
F4V19_RS15505	COG3850	Histidine kinase
F4V19_RS15505	COG2205	protein histidine kinase activity
F4V19_RS15510	COG1929	Belongs to the glycerate kinase type-1 family
F4V19_RS15515	COG4948	Mandelate Racemase Muconate Lactonizing
F4V19_RS15520	COG4948	Mandelate Racemase Muconate Lactonizing
F4V19_RS15525	COG2271	Major facilitator Superfamily
F4V19_RS15535	COG0716	FMN binding
F4V19_RS15545	COG3098	single-species biofilm formation
F4V19_RS15565	COG1611	Belongs to the LOG family
F4V19_RS15570	COG0814	amino acid
F4V19_RS15575	COG1760	l-serine dehydratase
F4V19_RS15585	COG1454	alcohol dehydrogenase
F4V19_RS15590	COG0235	Class ii aldolase
F4V19_RS15595	COG0738	Major facilitator superfamily
F4V19_RS15615	COG1349	DNA-binding transcription factor activity
F4V19_RS15625	COG2363	Small membrane protein
F4V19_RS15630	COG0583	DNA-binding transcription factor activity
F4V19_RS15640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F4V19_RS15645	COG2166	iron-sulfur cluster assembly
F4V19_RS15650	COG2962	Rard protein
F4V19_RS15655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F4V19_RS15660	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F4V19_RS15675	COG0860	N-Acetylmuramoyl-L-alanine amidase
F4V19_RS15685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F4V19_RS15690	COG1074	ATP-dependent DNA helicase activity
F4V19_RS15700	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F4V19_RS15705	COG4967	type IV pilus modification protein PilV
F4V19_RS15715	COG4795	General secretion pathway protein
F4V19_RS15720	COG2165	general secretion pathway protein
F4V19_RS15750	COG0861	Integral membrane protein TerC family
F4V19_RS15760	COG0667	Aldo Keto reductase
F4V19_RS15780	COG1609	Transcriptional regulator
F4V19_RS15790	COG0583	DNA-binding transcription factor activity
F4V19_RS15795	COG1794	racemase activity, acting on amino acids and derivatives
F4V19_RS15800	COG2814	Major facilitator Superfamily
F4V19_RS15805	COG1028	Short-chain dehydrogenase reductase Sdr
F4V19_RS15815	COG0183	Belongs to the thiolase family
F4V19_RS15830	COG0814	amino acid
F4V19_RS15865	COG3188	usher protein
F4V19_RS15905	COG4942	peptidase
F4V19_RS15960	COG1272	protein, Hemolysin III
F4V19_RS15970	COG2723	6-phospho-beta-galactosidase activity
F4V19_RS16000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F4V19_RS16005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F4V19_RS16010	COG0006	proline dipeptidase activity
F4V19_RS16030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F4V19_RS16035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F4V19_RS16050	COG2968	Membrane
F4V19_RS16060	COG0668	transmembrane transport
F4V19_RS16065	COG0191	fructose-bisphosphate aldolase activity
F4V19_RS16095	COG1122	ATPase activity
F4V19_RS16100	COG1122	ATPase activity
F4V19_RS16105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F4V19_RS16110	COG0501	Belongs to the peptidase M48B family
F4V19_RS16120	COG2267	carboxylic ester hydrolase activity
F4V19_RS16125	COG2731	YhcH YjgK YiaL family protein
F4V19_RS16130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F4V19_RS16135	COG1063	alcohol dehydrogenase
F4V19_RS16140	COG0246	Mannitol dehydrogenase
F4V19_RS16150	COG2186	Transcriptional regulator
F4V19_RS16160	COG1166	arginine decarboxylase activity
F4V19_RS16175	COG2814	Major facilitator Superfamily
F4V19_RS16185	COG2356	endonuclease I
F4V19_RS16190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F4V19_RS16215	COG2805	Type II/IV secretion system protein
F4V19_RS16220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F4V19_RS16225	COG0762	integral membrane protein
F4V19_RS16240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F4V19_RS16250	COG0252	asparaginase activity
F4V19_RS16260	COG3171	Protein conserved in bacteria
F4V19_RS16285	COG2211	Major facilitator Superfamily
F4V19_RS16290	COG1982	Orn Lys Arg decarboxylase major
F4V19_RS16295	COG1811	Na channel or pump
F4V19_RS16310	COG0427	acetyl-CoA hydrolase
F4V19_RS16315	COG2030	dehydratase
F4V19_RS16320	COG2301	Belongs to the HpcH HpaI aldolase family
F4V19_RS16350	COG0531	amino acid
F4V19_RS16360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F4V19_RS16365	COG1012	belongs to the aldehyde dehydrogenase family
F4V19_RS16390	COG2271	Major facilitator Superfamily
F4V19_RS16400	COG0246	Mannitol dehydrogenase
F4V19_RS16415	COG0754	glutathionylspermidine amidase activity
F4V19_RS16420	COG0625	glutathione transferase activity
F4V19_RS16430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F4V19_RS16435	COG0298	carbon dioxide binding
F4V19_RS16445	COG1773	rubredoxin
F4V19_RS16450	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F4V19_RS16455	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
F4V19_RS16460	COG5557	Pfam Polysulphide reductase, NrfD
F4V19_RS16465	COG0437	4 iron, 4 sulfur cluster binding
F4V19_RS16470	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
F4V19_RS16480	COG0840	transmembrane signaling receptor activity
F4V19_RS16505	COG1028	Short-chain dehydrogenase reductase Sdr
F4V19_RS16510	COG0848	biopolymer transport protein
F4V19_RS16530	COG2207	Transcriptional regulator
F4V19_RS16535	COG1979	alcohol dehydrogenase
F4V19_RS16545	COG0471	metal ion transport
F4V19_RS16585	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F4V19_RS16595	COG0515	serine threonine protein kinase
F4V19_RS16600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS16625	COG1137	ATPase activity
F4V19_RS16630	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F4V19_RS16635	COG3117	lipopolysaccharide transmembrane transporter activity
F4V19_RS16650	COG0530	calcium, potassium:sodium antiporter activity
F4V19_RS16655	COG1127	ABC transporter
F4V19_RS16660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F4V19_RS16665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F4V19_RS16670	COG2854	intermembrane phospholipid transfer
F4V19_RS16675	COG3113	response to antibiotic
F4V19_RS16680	COG5007	Belongs to the BolA IbaG family
F4V19_RS16690	COG3423	Transcriptional regulator
F4V19_RS16695	COG0142	geranyltranstransferase activity
F4V19_RS16710	COG0697	spore germination
F4V19_RS16720	COG2027	D-alanyl-D-alanine carboxypeptidase
F4V19_RS16730	COG1534	Rna-binding protein
F4V19_RS16745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F4V19_RS16755	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F4V19_RS16825	COG0513	Belongs to the DEAD box helicase family
F4V19_RS16830	COG0814	amino acid
F4V19_RS16840	COG3034	peptidoglycan biosynthetic process
F4V19_RS16845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F4V19_RS16855	COG0826	peptidase U32
F4V19_RS16860	COG0826	peptidase U32
F4V19_RS16865	COG3154	lipid carrier protein
F4V19_RS16870	COG3153	acetyltransferase
F4V19_RS16885	COG0693	protein deglycase activity
F4V19_RS16890	COG0702	epimerase
F4V19_RS16895	COG2823	Periplasmic or secreted lipoprotein
F4V19_RS16910	COG3107	peptidoglycan biosynthetic process
F4V19_RS16915	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F4V19_RS16925	COG1063	alcohol dehydrogenase
F4V19_RS16930	COG3775	system Galactitol-specific IIC component
F4V19_RS16935	COG3414	Phosphotransferase system galactitol-specific IIB component
F4V19_RS16940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS16955	COG2721	sulfolactate sulfo-lyase activity
F4V19_RS16965	COG2084	Dehydrogenase
F4V19_RS16970	COG1929	Belongs to the glycerate kinase type-1 family
F4V19_RS16980	COG0583	DNA-binding transcription factor activity
F4V19_RS17000	COG1882	Formate acetyltransferase
F4V19_RS17005	COG1760	l-serine dehydratase
F4V19_RS17010	COG0814	amino acid
F4V19_RS17025	COG1741	Belongs to the pirin family
F4V19_RS17030	COG0583	DNA-binding transcription factor activity
F4V19_RS17035	COG3152	Membrane
F4V19_RS17040	COG0435	Glutathione S-transferase
F4V19_RS17045	COG2259	Doxx family
F4V19_RS17055	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
F4V19_RS17060	COG4575	ribosome binding
F4V19_RS17065	COG1422	Protein of unknown function (DUF1090)
F4V19_RS17075	COG0586	Pfam SNARE associated Golgi protein
F4V19_RS17090	COG0673	inositol 2-dehydrogenase activity
F4V19_RS17095	COG2949	membrane
F4V19_RS17100	COG1451	nucleotide metabolic process
F4V19_RS17110	COG0446	pyridine nucleotide-disulphide oxidoreductase
F4V19_RS17110	COG1902	pentaerythritol trinitrate reductase activity
F4V19_RS17120	COG0840	transmembrane signaling receptor activity
F4V19_RS17125	COG0840	transmembrane signaling receptor activity
F4V19_RS17130	COG1695	Transcriptional regulator
F4V19_RS17140	COG4974	Belongs to the 'phage' integrase family
F4V19_RS17185	COG5002	protein histidine kinase activity
F4V19_RS17185	COG2176	DNA-directed DNA polymerase activity
F4V19_RS17215	COG4695	Portal protein
F4V19_RS17310	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS17360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F4V19_RS17385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F4V19_RS17400	COG4991	sh3 domain protein
F4V19_RS17405	COG3025	triphosphatase activity
F4V19_RS17425	COG2268	Band 7 protein
F4V19_RS17430	COG1585	Membrane protein implicated in regulation of membrane protease activity
F4V19_RS17470	COG3384	dioxygenase
F4V19_RS17475	COG0754	glutathionylspermidine amidase activity
F4V19_RS17490	COG0494	nUDIX hydrolase
F4V19_RS17495	COG3151	Protein conserved in bacteria
F4V19_RS17500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F4V19_RS17505	COG3150	esterase
F4V19_RS17515	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F4V19_RS17520	COG2249	NAD(P)H dehydrogenase (quinone) activity
F4V19_RS17525	COG0642	Histidine kinase
F4V19_RS17535	COG3111	PFAM Bacterial OB fold (BOF) protein
F4V19_RS17540	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F4V19_RS17610	COG5001	Diguanylate cyclase
F4V19_RS17610	COG3300	MHYT domain
F4V19_RS17675	COG0784	Response regulator, receiver
F4V19_RS17675	COG2198	Histidine kinase
F4V19_RS17675	COG5002	protein histidine kinase activity
F4V19_RS17680	COG1242	4 iron, 4 sulfur cluster binding
F4V19_RS17685	COG0070	glutamate synthase
F4V19_RS17685	COG0067	glutamate synthase
F4V19_RS17685	COG0069	glutamate synthase activity
F4V19_RS17690	COG0493	'glutamate synthase
F4V19_RS17695	COG4804	nuclease activity
F4V19_RS17700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F4V19_RS17705	COG0402	S-adenosylhomocysteine deaminase activity
F4V19_RS17710	COG2731	YhcH YjgK YiaL family protein
F4V19_RS17740	COG2969	positive regulation of protein catabolic process
F4V19_RS17745	COG0625	glutathione transferase activity
F4V19_RS17770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F4V19_RS17775	COG3105	Protein conserved in bacteria
F4V19_RS17780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F4V19_RS17800	COG5016	pyruvate
F4V19_RS17800	COG0511	ligase activity, forming carbon-carbon bonds
F4V19_RS17805	COG3630	sodium ion export across plasma membrane
F4V19_RS17810	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F4V19_RS17815	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F4V19_RS17820	COG0471	metal ion transport
F4V19_RS17830	COG2188	Transcriptional regulator
F4V19_RS17855	COG2732	(Barnase) inhibitor
F4V19_RS17875	COG0583	DNA-binding transcription factor activity
F4V19_RS17880	COG0312	modulator of DNA gyrase
F4V19_RS17885	COG3164	Protein of unknown function
F4V19_RS17900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F4V19_RS17905	COG1792	Involved in formation and maintenance of cell shape
F4V19_RS17910	COG1077	Cell shape determining protein MreB Mrl
F4V19_RS17915	COG2200	EAL domain
F4V19_RS17915	COG2199	diguanylate cyclase activity
F4V19_RS17920	COG0604	alcohol dehydrogenase
F4V19_RS17940	COG0511	ligase activity, forming carbon-carbon bonds
F4V19_RS17945	COG0439	Biotin carboxylase
F4V19_RS17950	COG3924	membrane
F4V19_RS17955	COG4145	pantothenate transmembrane transporter activity
F4V19_RS17980	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F4V19_RS17995	COG1309	transcriptional regulator
F4V19_RS18000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F4V19_RS18005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F4V19_RS18050	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F4V19_RS18070	COG0551	DNA topoisomerase type I activity
F4V19_RS18080	COG0758	DNA mediated transformation
F4V19_RS18110	COG3036	rescue of stalled ribosome
F4V19_RS18115	COG0789	Transcriptional regulator
F4V19_RS18155	COG0201	protein transport
F4V19_RS18235	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F4V19_RS18260	COG0051	transcription antitermination factor activity, RNA binding
F4V19_RS18315	COG2964	Protein conserved in bacteria
F4V19_RS18320	COG0545	Peptidyl-prolyl cis-trans isomerase
F4V19_RS18330	COG1047	Peptidyl-prolyl cis-trans
F4V19_RS18335	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F4V19_RS18350	COG0488	(ABC) transporter
F4V19_RS18365	COG0429	hydrolase of the alpha beta-hydrolase fold
F4V19_RS18375	COG3954	Phosphoribulokinase
F4V19_RS18380	COG1765	OsmC-like protein
F4V19_RS18390	COG1289	transmembrane transporter activity
F4V19_RS18425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F4V19_RS18465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F4V19_RS18470	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F4V19_RS18475	COG3266	domain, Protein
F4V19_RS18490	COG4796	Type ii and iii secretion system protein
F4V19_RS18505	COG3166	PFAM Fimbrial assembly family protein
F4V19_RS18510	COG4972	Pilus assembly protein
F4V19_RS18515	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F4V19_RS18520	COG0494	nUDIX hydrolase
F4V19_RS18530	COG1011	Hydrolase
F4V19_RS18535	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F4V19_RS18545	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F4V19_RS18565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F4V19_RS18570	COG2183	response to ionizing radiation
F4V19_RS18575	COG1918	ferrous iron import across plasma membrane
F4V19_RS18590	COG5464	transposase or invertase
F4V19_RS18610	COG2610	gluconate transmembrane transporter activity
F4V19_RS18615	COG1640	4-alpha-glucanotransferase
F4V19_RS18620	COG0058	SHG alpha-glucan phosphorylase activity
F4V19_RS18630	COG1349	DNA-binding transcription factor activity
F4V19_RS18635	COG0705	Rhomboid family
F4V19_RS18645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F4V19_RS18660	COG0371	Dehydrogenase
F4V19_RS18670	COG0129	dihydroxy-acid dehydratase activity
F4V19_RS18675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F4V19_RS18680	COG1414	Transcriptional regulator
F4V19_RS18685	COG0058	SHG alpha-glucan phosphorylase activity
F4V19_RS18705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F4V19_RS18720	COG2610	gluconate transmembrane transporter activity
F4V19_RS18725	COG3265	gluconokinase activity
F4V19_RS18730	COG1609	Transcriptional regulator
F4V19_RS18735	COG1741	Belongs to the pirin family
F4V19_RS18740	COG0673	inositol 2-dehydrogenase activity
F4V19_RS18745	COG1247	-acetyltransferase
F4V19_RS18750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F4V19_RS18765	COG1735	metal-dependent hydrolase with the TIM-barrel fold
F4V19_RS18770	COG0405	Gamma-glutamyltransferase
F4V19_RS18780	COG0584	glycerophosphoryl diester phosphodiesterase
F4V19_RS18860	COG2177	Part of the ABC transporter FtsEX involved in
F4V19_RS18865	COG2884	Cell division ATP-binding protein ftsE
F4V19_RS18870	COG0552	protein localization to endoplasmic reticulum
F4V19_RS18875	COG0742	ribosomal rna small subunit methyltransferase
F4V19_RS18880	COG3776	membrane
F4V19_RS18890	COG3714	YhhN family
F4V19_RS18910	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F4V19_RS18925	COG0628	permease
F4V19_RS18930	COG2091	lysine biosynthetic process via aminoadipic acid
F4V19_RS18940	COG0842	Transport permease protein
F4V19_RS18945	COG0842	Transport permease protein
F4V19_RS18945	COG1129	ABC transporter
F4V19_RS18950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F4V19_RS18955	COG2081	HI0933 family
F4V19_RS18960	COG0306	phosphate transporter
F4V19_RS18990	COG0671	phosphoesterase, PA-phosphatase related
F4V19_RS18995	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F4V19_RS19000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F4V19_RS19010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F4V19_RS19015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F4V19_RS19020	COG2222	sugar isomerase
F4V19_RS19025	COG2188	Transcriptional regulator
F4V19_RS19045	COG2197	response regulator
F4V19_RS19050	COG0583	DNA-binding transcription factor activity
F4V19_RS19055	COG1295	ribonuclease BN
F4V19_RS19060	COG0477	Major facilitator Superfamily
F4V19_RS19065	COG2982	Protein involved in outer membrane biogenesis
F4V19_RS19070	COG2200	EAL domain
F4V19_RS19075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F4V19_RS19090	COG2200	EAL domain
F4V19_RS19090	COG2199	diguanylate cyclase activity
F4V19_RS19150	COG0814	amino acid
F4V19_RS19155	COG4608	Belongs to the ABC transporter superfamily
F4V19_RS19160	COG0444	Belongs to the ABC transporter superfamily
F4V19_RS19165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F4V19_RS19170	COG0601	transmembrane transport
F4V19_RS19175	COG0747	negative chemotaxis
F4V19_RS19190	COG1609	Transcriptional regulator
F4V19_RS19245	COG5571	outer membrane autotransporter
F4V19_RS19250	COG2818	Glycosylase
F4V19_RS19255	COG0456	acetyltransferase
F4V19_RS19260	COG0243	molybdopterin cofactor binding
F4V19_RS19265	COG2885	chlorophyll binding
F4V19_RS19270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F4V19_RS19280	COG2944	sequence-specific DNA binding
F4V19_RS19285	COG1278	Cold shock
F4V19_RS19310	COG2801	Transposase and inactivated derivatives
F4V19_RS19335	COG3274	enterobacterial common antigen metabolic process
F4V19_RS19340	COG4682	membrane
F4V19_RS19345	COG1070	Carbohydrate kinase
F4V19_RS19355	COG2207	Transcriptional regulator
F4V19_RS19355	COG1609	Transcriptional regulator
F4V19_RS19360	COG2992	FlgJ-related protein
F4V19_RS19365	COG0366	Alpha amylase catalytic
F4V19_RS19370	COG3977	Valine--pyruvate aminotransferase
F4V19_RS19375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F4V19_RS19380	COG1414	Transcriptional regulator
F4V19_RS19390	COG2731	YhcH YjgK YiaL family protein
F4V19_RS19400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F4V19_RS19405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F4V19_RS19410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F4V19_RS19415	COG1070	Carbohydrate kinase
F4V19_RS19420	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
F4V19_RS19425	COG3623	hexulose-6-phosphate isomerase
F4V19_RS19430	COG0235	Class ii aldolase
F4V19_RS19445	COG1012	belongs to the aldehyde dehydrogenase family
F4V19_RS19450	COG1940	carbohydrate kinase activity
F4V19_RS19455	COG3276	selenocysteine insertion sequence binding
F4V19_RS19465	COG0625	glutathione transferase activity
F4V19_RS19470	COG1566	PFAM secretion protein HlyD family protein
F4V19_RS19485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS19485	COG2213	PTS system mannitol-specific
F4V19_RS19495	COG3722	fumarate hydratase activity
F4V19_RS19525	COG2186	Transcriptional regulator
F4V19_RS19535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F4V19_RS19540	COG1609	Transcriptional regulator
F4V19_RS19550	COG2271	Major facilitator Superfamily
F4V19_RS19570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F4V19_RS19575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F4V19_RS19585	COG4942	peptidase
F4V19_RS19590	COG2861	carbohydrate metabolic process
F4V19_RS19595	COG1216	Glycosyl transferase, family 2
F4V19_RS19675	COG0438	transferase activity, transferring glycosyl groups
F4V19_RS19680	COG0859	PFAM glycosyl transferase family 9
F4V19_RS19685	COG1519	Transferase
F4V19_RS19715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F4V19_RS19740	COG1561	YicC-like family, N-terminal region
F4V19_RS19745	COG0583	DNA-binding transcription factor activity
F4V19_RS19755	COG2860	membrane
F4V19_RS19775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F4V19_RS19780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F4V19_RS19785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F4V19_RS19800	COG2233	PERMEase
F4V19_RS19805	COG2982	Protein involved in outer membrane biogenesis
F4V19_RS19810	COG1501	Belongs to the glycosyl hydrolase 31 family
F4V19_RS19815	COG2211	Major facilitator Superfamily
F4V19_RS19855	COG2771	luxR family
F4V19_RS19870	COG3710	Transcriptional regulator
F4V19_RS19880	COG1335	isochorismatase
F4V19_RS19910	COG5464	transposase or invertase
F4V19_RS19925	COG3716	PTS system mannose fructose sorbose family IID component
F4V19_RS19930	COG3715	PTS system
F4V19_RS19935	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F4V19_RS19935	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS19955	COG2723	6-phospho-beta-galactosidase activity
F4V19_RS19995	COG3775	system Galactitol-specific IIC component
F4V19_RS20000	COG3414	Phosphotransferase system galactitol-specific IIB component
F4V19_RS20005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS20005	COG3711	transcriptional antiterminator
F4V19_RS20010	COG2188	Transcriptional regulator
F4V19_RS20045	COG0738	Major facilitator superfamily
F4V19_RS20055	COG1349	DNA-binding transcription factor activity
F4V19_RS20060	COG0440	acetolactate synthase activity
F4V19_RS20065	COG0028	Belongs to the TPP enzyme family
F4V19_RS20090	COG2814	Major facilitator Superfamily
F4V19_RS20100	COG0583	DNA-binding transcription factor activity
F4V19_RS20105	COG2610	gluconate transmembrane transporter activity
F4V19_RS20115	COG0641	radical SAM
F4V19_RS20125	COG2149	membrane
F4V19_RS20145	COG5645	(Lipo)protein
F4V19_RS20150	COG0823	Involved in the tonB-independent uptake of proteins
F4V19_RS20155	COG4235	cytochrome complex assembly
F4V19_RS20155	COG3088	subunit of a heme lyase
F4V19_RS20165	COG1138	Cytochrome C-type biogenesis protein
F4V19_RS20175	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F4V19_RS20180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F4V19_RS20185	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F4V19_RS20195	COG1858	cytochrome C peroxidase
F4V19_RS20210	COG3005	denitrification pathway
F4V19_RS20215	COG0745	RESPONSE REGULATOR receiver
F4V19_RS20220	COG1879	ABC-type sugar transport system periplasmic component
F4V19_RS20225	COG0784	Response regulator, receiver
F4V19_RS20225	COG2198	Histidine kinase
F4V19_RS20225	COG2205	protein histidine kinase activity
F4V19_RS20230	COG2271	Major facilitator Superfamily
F4V19_RS20240	COG0800	Aldolase
F4V19_RS20245	COG3734	2-keto-3-deoxy-galactonokinase
F4V19_RS20250	COG2186	Transcriptional regulator
F4V19_RS20255	COG0561	phosphatase activity
F4V19_RS20330	COG2091	lysine biosynthetic process via aminoadipic acid
F4V19_RS20335	COG0431	NADPH-dependent FMN reductase
F4V19_RS20340	COG2252	PERMEase
F4V19_RS20345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F4V19_RS20350	COG0704	Plays a role in the regulation of phosphate uptake
F4V19_RS20360	COG0581	inorganic phosphate transmembrane transporter activity
F4V19_RS20365	COG0573	inorganic phosphate transmembrane transporter activity
F4V19_RS20370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F4V19_RS20375	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F4V19_RS20375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F4V19_RS20375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F4V19_RS20380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F4V19_RS20385	COG4533	DNA binding
F4V19_RS20445	COG3312	ion transport
F4V19_RS20460	COG0716	FMN binding
F4V19_RS20465	COG1522	sequence-specific DNA binding
F4V19_RS20500	COG1172	Belongs to the binding-protein-dependent transport system permease family
F4V19_RS20510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F4V19_RS20515	COG1609	Transcriptional regulator
F4V19_RS20520	COG0477	Major facilitator Superfamily
F4V19_RS20525	COG2186	Transcriptional regulator
F4V19_RS20585	COG3978	acetolactate synthase activity
F4V19_RS20635	COG3201	nicotinamide mononucleotide transporter
F4V19_RS20655	COG3118	belongs to the thioredoxin family
F4V19_RS20675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F4V19_RS20690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F4V19_RS20695	COG1088	dTDP-glucose 4,6-dehydratase activity
F4V19_RS20700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F4V19_RS20705	COG0456	acetyltransferase
F4V19_RS20710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F4V19_RS20715	COG2244	polysaccharide biosynthetic process
F4V19_RS20760	COG3071	HemY protein
F4V19_RS20765	COG2959	enzyme of heme biosynthesis
F4V19_RS20815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F4V19_RS20820	COG1011	Hydrolase
F4V19_RS20865	COG1280	lysine exporter protein (LysE YggA)
F4V19_RS20875	COG2267	carboxylic ester hydrolase activity
F4V19_RS20880	COG0561	phosphatase activity
F4V19_RS20900	COG0641	radical SAM
F4V19_RS20945	COG0805	protein transport
F4V19_RS20990	COG1739	Uncharacterized protein family UPF0029
F4V19_RS21030	COG1763	Mo-molybdopterin cofactor biosynthetic process
F4V19_RS21035	COG0746	molybdenum cofactor guanylyltransferase activity
F4V19_RS21040	COG3084	Protein conserved in bacteria
F4V19_RS21055	COG0204	Acyl-transferase
F4V19_RS21110	COG0561	phosphatase activity
F4V19_RS21155	COG1501	Belongs to the glycosyl hydrolase 31 family
F4V19_RS21160	COG2017	converts alpha-aldose to the beta-anomer
F4V19_RS21170	COG3684	Belongs to the aldolase LacD family
F4V19_RS21180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F4V19_RS21185	COG1349	DNA-binding transcription factor activity
F4V19_RS21190	COG1011	Hydrolase
F4V19_RS21205	COG0456	acetyltransferase
F4V19_RS21210	COG5499	transcription regulator containing HTH domain
F4V19_RS21215	COG4680	protein conserved in bacteria
F4V19_RS21225	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F4V19_RS21240	COG2864	formate dehydrogenase
F4V19_RS21245	COG0437	4 iron, 4 sulfur cluster binding
F4V19_RS21290	COG1454	alcohol dehydrogenase
F4V19_RS21300	COG4806	L-rhamnose isomerase
F4V19_RS21335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F4V19_RS21345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F4V19_RS21350	COG2258	MOSC domain
F4V19_RS21365	COG2205	protein histidine kinase activity
F4V19_RS21370	COG0745	RESPONSE REGULATOR receiver
F4V19_RS21375	COG3678	ATP-independent chaperone mediated protein folding
F4V19_RS21400	COG2211	Major facilitator Superfamily
F4V19_RS21405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F4V19_RS21415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F4V19_RS21435	COG1070	Carbohydrate kinase
F4V19_RS21490	COG3152	Membrane
F4V19_RS21500	COG1494	fructose-1,6-bisphosphatase
F4V19_RS21510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F4V19_RS21525	COG1575	Belongs to the MenA family. Type 1 subfamily
F4V19_RS21540	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F4V19_RS21545	COG1609	Transcriptional regulator
F4V19_RS21550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F4V19_RS21575	COG0626	cystathionine gamma-synthase activity
F4V19_RS21580	COG0527	aspartate kinase activity
F4V19_RS21580	COG0460	homoserine dehydrogenase
F4V19_RS21585	COG0668	transmembrane transport
F4V19_RS21600	COG0737	Belongs to the 5'-nucleotidase family
F4V19_RS21620	COG0371	Dehydrogenase
F4V19_RS21630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS21630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS21630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F4V19_RS21635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F4V19_RS21640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F4V19_RS21645	COG1882	Formate acetyltransferase
F4V19_RS21650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F4V19_RS21655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F4V19_RS21660	COG2207	Transcriptional regulator
F4V19_RS21695	COG0583	DNA-binding transcription factor activity
F4V19_RS21755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F4V19_RS21805	COG0250	Participates in transcription elongation, termination and antitermination
F4V19_RS21870	COG2104	thiamine diphosphate biosynthetic process
F4V19_RS21875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F4V19_RS21940	COG0151	Belongs to the GarS family
F4V19_RS21980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F4V19_RS22025	COG3122	Protein conserved in bacteria
F4V19_RS22065	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS22095	COG2246	polysaccharide biosynthetic process
F4V19_RS22180	COG0527	aspartate kinase activity
F4V19_RS22205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F4V19_RS22260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F4V19_RS22270	COG0534	Mate efflux family protein
F4V19_RS22285	COG0735	belongs to the Fur family
F4V19_RS22295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F4V19_RS22325	COG3700	Belongs to the class B bacterial acid phosphatase family
F4V19_RS22335	COG2315	Protein conserved in bacteria
F4V19_RS22395	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F4V19_RS22415	COG2252	PERMEase
F4V19_RS22420	COG0025	NhaP-type Na H and K H
F4V19_RS22425	COG0583	DNA-binding transcription factor activity
F4V19_RS22430	COG1380	Effector of murein hydrolase LrgA
F4V19_RS22435	COG1346	cytolysis
F4V19_RS22445	COG3162	membrane
F4V19_RS22460	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
F4V19_RS22465	COG0437	4 iron, 4 sulfur cluster binding
F4V19_RS22470	COG3301	Polysulphide reductase, NrfD
F4V19_RS22475	COG1138	Cytochrome C-type biogenesis protein
F4V19_RS22480	COG3088	subunit of a heme lyase
F4V19_RS22485	COG4235	cytochrome complex assembly
F4V19_RS22490	COG1301	dicarboxylic acid transport
F4V19_RS22495	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F4V19_RS22515	COG2764	glyoxalase bleomycin resistance protein dioxygenase
F4V19_RS22520	COG2824	Alkylphosphonate utilization operon protein PhnA
F4V19_RS22550	COG0531	amino acid
F4V19_RS22555	COG2207	Transcriptional regulator
F4V19_RS22560	COG1982	Orn Lys Arg decarboxylase major
F4V19_RS22565	COG2169	Transcriptional regulator
F4V19_RS22580	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F4V19_RS22580	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F4V19_RS22585	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F4V19_RS22595	COG4565	transcriptional regulatory protein
F4V19_RS22600	COG3290	protein histidine kinase activity
F4V19_RS22605	COG0243	molybdopterin cofactor binding
F4V19_RS22610	COG0437	4 iron, 4 sulfur cluster binding
F4V19_RS22615	COG3302	dmso reductase anchor subunit
F4V19_RS22620	COG3381	protein complex oligomerization
F4V19_RS22645	COG2197	response regulator
F4V19_RS22695	COG1309	transcriptional regulator
F4V19_RS22710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F4V19_RS22715	COG1027	Aspartate ammonia-lyase
F4V19_RS22720	COG3030	protein affecting phage T7 exclusion by the F plasmid
F4V19_RS22725	COG0531	amino acid
F4V19_RS22765	COG5510	response to toxic substance
F4V19_RS22795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F4V19_RS22800	COG1053	succinate dehydrogenase
F4V19_RS22820	COG1511	domain protein
F4V19_RS22820	COG3264	Mechanosensitive ion channel
F4V19_RS22840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F4V19_RS22865	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F4V19_RS22865	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F4V19_RS22870	COG0802	atpase or kinase
F4V19_RS22895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F4V19_RS22900	COG0330	HflC and HflK could
F4V19_RS22905	COG0330	HflC and HflK could
F4V19_RS22910	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F4V19_RS22925	COG0557	exoribonuclease II activity
F4V19_RS22935	COG3789	protein conserved in bacteria
F4V19_RS22940	COG1842	Phage shock protein A
F4V19_RS22955	COG3766	membrane
F4V19_RS22960	COG5463	Belongs to the UPF0441 family
F4V19_RS22965	COG0754	glutathionylspermidine amidase activity
F4V19_RS22970	COG1960	acyl-CoA dehydrogenase activity
F4V19_RS22980	COG3650	response to hydrogen peroxide
F4V19_RS22985	COG1073	alpha beta
F4V19_RS23055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F4V19_RS23070	COG3061	Opacity-associated protein A
F4V19_RS23075	COG0545	Peptidyl-prolyl cis-trans isomerase
F4V19_RS23080	COG1113	amino acid transport
F4V19_RS23100	COG0697	spore germination
F4V19_RS23105	COG0702	epimerase
F4V19_RS23110	COG1733	regulation of RNA biosynthetic process
F4V19_RS23125	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F4V19_RS23135	COG1253	flavin adenine dinucleotide binding
F4V19_RS23155	COG2105	PFAM AIG2 family protein
F4V19_RS23160	COG2271	Major facilitator Superfamily
F4V19_RS23165	COG3964	amidohydrolase
F4V19_RS23180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F4V19_RS23190	COG0312	modulator of DNA gyrase
F4V19_RS23225	COG3964	amidohydrolase
F4V19_RS23240	COG3711	transcriptional antiterminator
F4V19_RS23240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS23245	COG3077	Addiction module antitoxin, RelB DinJ family
F4V19_RS23250	COG2026	Addiction module toxin, RelE StbE family
F4V19_RS23265	COG0366	Alpha amylase catalytic
F4V19_RS23270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F4V19_RS23270	COG1263	PTS System
F4V19_RS23320	COG1438	arginine binding
F4V19_RS23325	COG1288	antiporter activity
F4V19_RS23345	COG2731	YhcH YjgK YiaL family protein
F4V19_RS23385	COG2927	DNA polymerase III (CHI subunit)
F4V19_RS23395	COG0795	lipopolysaccharide-transporting ATPase activity
F4V19_RS23400	COG0795	lipopolysaccharide-transporting ATPase activity
F4V19_RS23405	COG1609	Transcriptional regulator
F4V19_RS23410	COG2610	gluconate transmembrane transporter activity
F4V19_RS23415	COG1028	Short-chain dehydrogenase reductase Sdr
F4V19_RS23420	COG1063	alcohol dehydrogenase
F4V19_RS23425	COG3265	gluconokinase activity
F4V19_RS23430	COG1064	alcohol dehydrogenase
F4V19_RS23440	COG0582	viral genome integration into host DNA
F4V19_RS23445	COG3423	Transcriptional regulator
F4V19_RS23480	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
F4V19_RS23520	COG2378	regulation of single-species biofilm formation
F4V19_RS23545	COG2003	Belongs to the UPF0758 family
F4V19_RS23605	COG3423	Transcriptional regulator
F4V19_RS23700	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F4V19_RS23725	COG0412	Dienelactone hydrolase
F4V19_RS23730	COG2186	Transcriptional regulator
F4V19_RS23750	COG0583	DNA-binding transcription factor activity
F4V19_RS23755	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F4V19_RS23760	COG0700	Nucleoside recognition
F4V19_RS23765	COG3366	ferrous iron transmembrane transporter activity
F4V19_RS23775	COG0477	Major facilitator Superfamily
F4V19_RS23780	COG2733	membrane
F4V19_RS23790	COG5464	transposase or invertase
F4V19_RS23795	COG1012	belongs to the aldehyde dehydrogenase family
F4V19_RS23810	COG3586	endonuclease activity
F4V19_RS23825	COG0732	type I restriction modification DNA specificity domain
F4V19_RS23845	COG0523	cobalamin synthesis protein
F4V19_RS23850	COG2879	small protein
F4V19_RS23855	COG1966	Carbon starvation protein
F4V19_RS23860	COG0840	transmembrane signaling receptor activity
F4V19_RS23875	COG1484	DNA-dependent DNA replication
F4V19_RS23890	COG2966	Psort location CytoplasmicMembrane, score
F4V19_RS23895	COG2197	response regulator
F4V19_RS23900	COG2197	response regulator
F4V19_RS23905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F4V19_RS23910	COG4114	ferric iron reductase
F4V19_RS23915	COG3706	GGDEF domain
F4V19_RS23945	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
F4V19_RS23955	COG1011	Hydrolase
F4V19_RS23965	COG2823	Periplasmic or secreted lipoprotein
F4V19_RS23975	COG4667	esterase of the alpha-beta hydrolase superfamily
F4V19_RS23980	COG0084	hydrolase, TatD family'
F4V19_RS23985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F4V19_RS23990	COG1328	CTP reductase activity
F4V19_RS24020	COG3188	usher protein
F4V19_RS24025	COG3121	Chaperone
F4V19_RS24030	COG3539	Fimbrial protein
F4V19_RS24045	COG3726	membrane protein affecting hemolysin expression
F4V19_RS24050	COG0560	Phosphoserine phosphatase
F4V19_RS24065	COG0488	(ABC) transporter
F4V19_RS24090	COG2207	Transcriptional regulator
F4V19_RS24090	COG3708	Transcriptional regulator
F4V19_RS24095	COG3045	CreA protein
F4V19_RS24100	COG0745	RESPONSE REGULATOR receiver
F4V19_RS24105	COG2205	protein histidine kinase activity
F4V19_RS24110	COG4452	Inner membrane protein CreD
F4V19_RS24130	COG3121	Chaperone
F4V19_RS24150	COG0745	RESPONSE REGULATOR receiver
F4V19_RS24160	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F4V19_RS24170	COG0527	aspartate kinase activity
F4V19_RS24170	COG0460	homoserine dehydrogenase
F4V19_RS24180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F4V19_RS24190	COG1115	amino acid carrier protein
F4V19_RS24200	COG0521	Mo-molybdopterin cofactor biosynthetic process
F4V19_RS24205	COG1584	GPR1 FUN34 yaaH family protein
F4V19_RS24210	COG4735	regulation of single-species biofilm formation
F4V19_RS24275	COG3188	usher protein
F4V19_RS24290	COG3539	Fimbrial protein
F4V19_RS24295	COG3121	Chaperone
F4V19_RS24315	COG0583	DNA-binding transcription factor activity
F4V19_RS24330	COG0737	Belongs to the 5'-nucleotidase family
F4V19_RS24340	COG3119	arylsulfatase activity
F4V19_RS24345	COG0641	radical SAM
F4V19_RS24365	COG0583	DNA-binding transcription factor activity
F4V19_RS24390	COG0196	riboflavin kinase activity
F4V19_RS24405	COG1047	Peptidyl-prolyl cis-trans
F4V19_RS24435	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
F4V19_RS24440	COG0511	ligase activity, forming carbon-carbon bonds
F4V19_RS24440	COG5016	pyruvate
F4V19_RS24550	COG0644	oxidoreductase
F4V19_RS24560	COG2271	Major facilitator Superfamily
F4V19_RS24580	COG3119	arylsulfatase activity
F4V19_RS24615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F4V19_RS24645	COG0417	DNA replication proofreading
F4V19_RS24685	COG0586	Pfam SNARE associated Golgi protein
F4V19_RS24775	COG0768	penicillin binding
F4V19_RS24785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F4V19_RS24800	COG0772	Belongs to the SEDS family
F4V19_RS24825	COG0849	cell division
F4V19_RS24830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F4V19_RS24850	COG0494	nUDIX hydrolase
F4V19_RS24855	COG0667	Aldo Keto reductase
F4V19_RS24860	COG0583	DNA-binding transcription factor activity
F4V19_RS24885	COG1459	type II secretion system
F4V19_RS24890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F4V19_RS24895	COG4969	Belongs to the N-Me-Phe pilin family
F4V19_RS24910	COG3725	Membrane protein required for beta-lactamase induction
F4V19_RS24915	COG3940	Belongs to the glycosyl hydrolase 43 family
F4V19_RS24920	COG2211	Major facilitator Superfamily
F4V19_RS24935	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F4V19_RS24940	COG0508	dehydrogenase complex catalyzes the overall conversion of
F4V19_RS24945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F4V19_RS24960	COG3064	Membrane
F4V19_RS25000	COG1349	DNA-binding transcription factor activity
F4V19_RS25020	COG2132	Multicopper oxidase
F4V19_RS25025	COG4993	Dehydrogenase
F4V19_RS25035	COG0288	reversible hydration of carbon dioxide
F4V19_RS25040	COG1131	(ABC) transporter
F4V19_RS25045	COG0842	Transport permease protein
F4V19_RS25050	COG3539	Fimbrial protein
F4V19_RS25070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F4V19_RS25075	COG0726	polysaccharide deacetylase
F4V19_RS25095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F4V19_RS25120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F4V19_RS25125	COG1643	Atp-dependent helicase
F4V19_RS25130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F4V19_RS25135	COG4774	siderophore transport
F4V19_RS25140	COG1120	ATPase activity
F4V19_RS25145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F4V19_RS25160	COG3188	usher protein
F4V19_RS25165	COG3121	Chaperone
F4V19_RS25170	COG3539	Fimbrial protein
F4V19_RS25175	COG3539	Fimbrial protein
F4V19_RS25205	COG2860	membrane
F4V19_RS25230	COG3835	regulator
F4V19_RS25240	COG0477	Major facilitator Superfamily
F4V19_RS25290	COG0575	Belongs to the CDS family
F4V19_RS25340	COG0587	DNA-directed DNA polymerase activity
F4V19_RS25355	COG1982	Orn Lys Arg decarboxylase major
F4V19_RS25360	COG0346	lactoylglutathione lyase activity
F4V19_RS25370	COG4568	rho-dependent transcription termination
F4V19_RS25385	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F4V19_RS25390	COG3015	lipoprotein NlpE involved in copper resistance
F4V19_RS25400	COG1720	tRNA m6t6A37 methyltransferase activity
F4V19_RS25425	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F4V19_RS25465	COG0583	DNA-binding transcription factor activity
F4V19_RS25470	COG2814	Major facilitator Superfamily
F4V19_RS25480	COG2226	methyltransferase
F4V19_RS25485	COG1388	LysM domain
F4V19_RS25485	COG0741	lytic transglycosylase activity
F4V19_RS25495	COG2226	methyltransferase
F4V19_RS25680	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F4V19_RS25695	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
F4V19_RS25855	COG3772	lysozyme
F4V19_RS25885	COG1475	DNA binding
F4V19_RS25900	COG1475	DNA binding
F4V19_RS26040	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS26055	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS26060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F4V19_RS26125	COG5492	domain, Protein
F4V19_RS26125	COG4932	domain protein
F4V19_RS26170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F4V19_RS26175	COG1475	DNA binding
F4V19_RS26180	COG1475	DNA binding
F4V19_RS26185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F4V19_RS26295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F4V19_RS26350	COG0328	RNA-DNA hybrid ribonuclease activity
F4V19_RS26370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F4V19_RS26380	COG0237	dephospho-CoA kinase activity
F4V19_RS26385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F4V19_RS26395	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F4V19_RS26405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F4V19_RS26410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F4V19_RS26490	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F4V19_RS26500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F4V19_RS26560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F4V19_RS26575	COG1702	phosphate starvation-inducible protein PhoH
F4V19_RS26725	COG5301	cellulose 1,4-beta-cellobiosidase activity
F4V19_RS26755	COG3941	tape measure