locus-tag	class	description
RK54_RS00025	COG4942	peptidase
RK54_RS00035	COG0582	viral genome integration into host DNA
RK54_RS00055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS00055	COG2213	PTS system mannitol-specific
RK54_RS00060	COG3414	Phosphotransferase system galactitol-specific IIB component
RK54_RS00065	COG3775	system Galactitol-specific IIC component
RK54_RS00070	COG0698	ribose 5-phosphate isomerase
RK54_RS00075	COG1349	DNA-binding transcription factor activity
RK54_RS00080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS00085	COG3414	Phosphotransferase system galactitol-specific IIB component
RK54_RS00090	COG3775	system Galactitol-specific IIC component
RK54_RS00095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RK54_RS00100	COG1028	Short-chain dehydrogenase reductase Sdr
RK54_RS00105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RK54_RS00130	COG3188	usher protein
RK54_RS00165	COG0814	amino acid
RK54_RS00180	COG0183	Belongs to the thiolase family
RK54_RS00200	COG1028	Short-chain dehydrogenase reductase Sdr
RK54_RS00205	COG2814	Major facilitator Superfamily
RK54_RS00210	COG1794	racemase activity, acting on amino acids and derivatives
RK54_RS00215	COG0583	DNA-binding transcription factor activity
RK54_RS00225	COG1609	Transcriptional regulator
RK54_RS00255	COG0667	Aldo Keto reductase
RK54_RS00265	COG0861	Integral membrane protein TerC family
RK54_RS00300	COG2165	general secretion pathway protein
RK54_RS00305	COG4795	General secretion pathway protein
RK54_RS00315	COG4967	type IV pilus modification protein PilV
RK54_RS00320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
RK54_RS00330	COG1074	ATP-dependent DNA helicase activity
RK54_RS00335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RK54_RS00345	COG0860	N-Acetylmuramoyl-L-alanine amidase
RK54_RS00360	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RK54_RS00365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RK54_RS00370	COG2962	Rard protein
RK54_RS00375	COG2166	iron-sulfur cluster assembly
RK54_RS00380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RK54_RS00390	COG0583	DNA-binding transcription factor activity
RK54_RS00395	COG2363	Small membrane protein
RK54_RS00405	COG1349	DNA-binding transcription factor activity
RK54_RS00425	COG0738	Major facilitator superfamily
RK54_RS00430	COG0235	Class ii aldolase
RK54_RS00435	COG1454	alcohol dehydrogenase
RK54_RS00450	COG1760	l-serine dehydratase
RK54_RS00455	COG0814	amino acid
RK54_RS00460	COG1611	Belongs to the LOG family
RK54_RS00480	COG3098	single-species biofilm formation
RK54_RS00490	COG0716	FMN binding
RK54_RS00500	COG2271	Major facilitator Superfamily
RK54_RS00505	COG4948	Mandelate Racemase Muconate Lactonizing
RK54_RS00510	COG4948	Mandelate Racemase Muconate Lactonizing
RK54_RS00515	COG1929	Belongs to the glycerate kinase type-1 family
RK54_RS00520	COG3850	Histidine kinase
RK54_RS00520	COG4999	Histidine kinase
RK54_RS00520	COG3437	response regulator, receiver
RK54_RS00520	COG2205	protein histidine kinase activity
RK54_RS00530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RK54_RS00535	COG3609	addiction module antidote protein, CC2985 family
RK54_RS00570	COG3539	Fimbrial protein
RK54_RS00575	COG3121	Chaperone
RK54_RS00580	COG3188	usher protein
RK54_RS00585	COG3539	Fimbrial protein
RK54_RS00590	COG3956	TIGRFAM MazG family protein
RK54_RS00605	COG0602	queuosine metabolic process
RK54_RS00610	COG0321	lipoyl(octanoyl) transferase activity
RK54_RS00610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RK54_RS00615	COG0720	synthase
RK54_RS00625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RK54_RS00660	COG1203	CRISPR-associated helicase, Cas3
RK54_RS00675	COG1857	crispr-associated protein
RK54_RS00690	COG1518	maintenance of DNA repeat elements
RK54_RS00695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RK54_RS00700	COG2234	aminopeptidase activity
RK54_RS00770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RK54_RS00775	COG0163	prenyltransferase activity
RK54_RS00785	COG1349	DNA-binding transcription factor activity
RK54_RS00790	COG2084	Dehydrogenase
RK54_RS00800	COG0235	Class ii aldolase
RK54_RS00805	COG3622	Belongs to the hyi family
RK54_RS00810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK54_RS00815	COG2610	gluconate transmembrane transporter activity
RK54_RS00825	COG0477	Major facilitator Superfamily
RK54_RS00890	COG2207	Transcriptional regulator
RK54_RS00980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RK54_RS01070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK54_RS01075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK54_RS01080	COG1121	(ABC) transporter
RK54_RS01100	COG0309	Hydrogenase expression formation protein (HypE)
RK54_RS01105	COG0409	Hydrogenase expression formation protein
RK54_RS01110	COG0298	carbon dioxide binding
RK54_RS01115	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RK54_RS01135	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RK54_RS01140	COG0651	ATP synthesis coupled electron transport
RK54_RS01145	COG0650	Formate hydrogenlyase subunit 4
RK54_RS01150	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
RK54_RS01150	COG3261	NADH dehydrogenase
RK54_RS01155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RK54_RS01160	COG3260	NADH ubiquinone oxidoreductase 20
RK54_RS01170	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RK54_RS01180	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RK54_RS01185	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RK54_RS01205	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RK54_RS01205	COG0517	IMP dehydrogenase activity
RK54_RS01210	COG1349	DNA-binding transcription factor activity
RK54_RS01215	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
RK54_RS01230	COG3732	PTS system glucitol sorbitol-specific
RK54_RS01235	COG3730	PTS system glucitol sorbitol-specific
RK54_RS01240	COG2951	lytic endotransglycosylase activity
RK54_RS01250	COG1546	Belongs to the CinA family
RK54_RS01275	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
RK54_RS01310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK54_RS01315	COG1238	metal cluster binding
RK54_RS01335	COG2814	Major facilitator Superfamily
RK54_RS01340	COG1566	PFAM secretion protein HlyD family protein
RK54_RS01345	COG1846	Transcriptional regulator
RK54_RS01350	COG2814	Major facilitator Superfamily
RK54_RS01400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RK54_RS01410	COG4575	ribosome binding
RK54_RS01435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RK54_RS01440	COG0640	Transcriptional regulator
RK54_RS01445	COG0401	homolog of Blt101
RK54_RS01455	COG1652	LysM domain
RK54_RS01460	COG1802	Transcriptional regulator
RK54_RS01465	COG1113	amino acid transport
RK54_RS01470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RK54_RS01475	COG1012	belongs to the aldehyde dehydrogenase family
RK54_RS01480	COG0579	oxidoreductase
RK54_RS01515	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RK54_RS01530	COG2990	Protein conserved in bacteria
RK54_RS01555	COG2819	hydrolase of the alpha beta superfamily
RK54_RS01565	COG1132	(ABC) transporter
RK54_RS01620	COG0582	viral genome integration into host DNA
RK54_RS01650	COG2190	(PTS) system
RK54_RS01650	COG1263	PTS System
RK54_RS01650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK54_RS01660	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RK54_RS01665	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RK54_RS01675	COG0673	inositol 2-dehydrogenase activity
RK54_RS01695	COG3423	Transcriptional regulator
RK54_RS01710	COG4133	protoheme IX ABC transporter activity
RK54_RS01750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RK54_RS01775	COG2867	negative regulation of translational initiation
RK54_RS01790	COG0497	DNA recombination
RK54_RS01815	COG4536	flavin adenine dinucleotide binding
RK54_RS01820	COG4137	Cytochrome C assembly protein
RK54_RS01830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RK54_RS01855	COG2199	diguanylate cyclase activity
RK54_RS01870	COG1605	Chorismate mutase
RK54_RS01870	COG0287	Prephenate dehydrogenase
RK54_RS01880	COG1605	Chorismate mutase
RK54_RS01880	COG0077	Prephenate dehydratase
RK54_RS01890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RK54_RS01895	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RK54_RS01910	COG0542	response to heat
RK54_RS01945	COG0477	Major facilitator Superfamily
RK54_RS01950	COG5544	Lipoprotein
RK54_RS01955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RK54_RS01965	COG3148	PFAM DTW domain containing protein
RK54_RS01970	COG3118	belongs to the thioredoxin family
RK54_RS01975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RK54_RS01995	COG0583	DNA-binding transcription factor activity
RK54_RS02000	COG0513	Belongs to the DEAD box helicase family
RK54_RS02035	COG3086	response to oxidative stress
RK54_RS02085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RK54_RS02090	COG0583	DNA-binding transcription factor activity
RK54_RS02095	COG2223	nitrite transmembrane transporter activity
RK54_RS02100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK54_RS02105	COG1737	Transcriptional regulator
RK54_RS02115	COG1263	PTS System
RK54_RS02115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK54_RS02120	COG0560	Phosphoserine phosphatase
RK54_RS02145	COG2205	protein histidine kinase activity
RK54_RS02150	COG3170	Tfp pilus assembly protein FimV
RK54_RS02155	COG2204	response regulator
RK54_RS02160	COG0347	Belongs to the P(II) protein family
RK54_RS02165	COG3104	oligopeptide transport
RK54_RS02175	COG0531	amino acid
RK54_RS02180	COG3710	Transcriptional regulator
RK54_RS02195	COG2814	Major facilitator Superfamily
RK54_RS02200	COG3711	transcriptional antiterminator
RK54_RS02210	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
RK54_RS02255	COG0822	iron-sulfur transferase activity
RK54_RS02275	COG0633	Ferredoxin
RK54_RS02280	COG2975	iron-sulfur cluster assembly
RK54_RS02315	COG2897	thiosulfate sulfurtransferase activity
RK54_RS02320	COG2373	Large extracellular alpha-helical protein
RK54_RS02325	COG4953	penicillin-binding protein 1C
RK54_RS02330	COG0243	molybdopterin cofactor binding
RK54_RS02335	COG0437	4 iron, 4 sulfur cluster binding
RK54_RS02380	COG2976	Protein conserved in bacteria
RK54_RS02395	COG1645	bacterial-type flagellum-dependent swarming motility
RK54_RS02440	COG0516	GMP reductase activity
RK54_RS02440	COG0517	IMP dehydrogenase activity
RK54_RS02475	COG2200	EAL domain
RK54_RS02490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RK54_RS02510	COG2233	PERMEase
RK54_RS02520	COG1393	Belongs to the ArsC family
RK54_RS02530	COG0628	permease
RK54_RS02535	COG1929	Belongs to the glycerate kinase type-1 family
RK54_RS02540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RK54_RS02545	COG2716	regulation of RNA biosynthetic process
RK54_RS02555	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
RK54_RS02565	COG2321	neutral zinc metallopeptidase
RK54_RS02585	COG1393	Belongs to the ArsC family
RK54_RS02595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK54_RS02600	COG3850	Histidine kinase
RK54_RS02610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RK54_RS02610	COG0493	'glutamate synthase
RK54_RS02630	COG5342	invasion associated locus B
RK54_RS02640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RK54_RS02775	COG2837	iron assimilation
RK54_RS02795	COG4208	sulfate ABC transporter
RK54_RS02850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS02880	COG3530	Putative quorum-sensing-regulated virulence factor
RK54_RS02885	COG0385	Bile acid
RK54_RS02890	COG0583	DNA-binding transcription factor activity
RK54_RS02900	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RK54_RS02905	COG2211	Major facilitator Superfamily
RK54_RS02915	COG0583	DNA-binding transcription factor activity
RK54_RS02945	COG3415	Transposase
RK54_RS02950	COG3415	Transposase
RK54_RS02970	COG2200	EAL domain
RK54_RS02970	COG2199	diguanylate cyclase activity
RK54_RS02975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK54_RS02990	COG0667	Aldo Keto reductase
RK54_RS02995	COG3961	Belongs to the TPP enzyme family
RK54_RS03015	COG0436	Aminotransferase
RK54_RS03035	COG1560	Kdo2-lipid A biosynthetic process
RK54_RS03130	COG0582	viral genome integration into host DNA
RK54_RS03140	COG2116	formate transmembrane transporter activity
RK54_RS03155	COG3691	Protein conserved in bacteria
RK54_RS03170	COG2062	phosphohistidine phosphatase, SixA
RK54_RS03195	COG0730	response to heat
RK54_RS03200	COG3101	peptidyl-lysine hydroxylation
RK54_RS03215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RK54_RS03235	COG3423	Transcriptional regulator
RK54_RS03260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RK54_RS03270	COG0586	Pfam SNARE associated Golgi protein
RK54_RS03280	COG0285	dihydrofolate synthase activity
RK54_RS03285	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
RK54_RS03290	COG1286	toxin biosynthetic process
RK54_RS03295	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RK54_RS03300	COG3829	transcription factor binding
RK54_RS03310	COG0531	amino acid
RK54_RS03315	COG3457	Alanine racemase
RK54_RS03320	COG0833	amino acid
RK54_RS03360	COG1090	epimerase
RK54_RS03365	COG0625	glutathione transferase activity
RK54_RS03370	COG0625	glutathione transferase activity
RK54_RS03375	COG0622	Phosphoesterase
RK54_RS03385	COG1609	Transcriptional regulator
RK54_RS03395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS03405	COG3037	sugar-specific permease SgaT UlaA
RK54_RS03410	COG3959	Transketolase, thiamine diphosphate binding domain
RK54_RS03415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RK54_RS03420	COG1288	antiporter activity
RK54_RS03445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK54_RS03450	COG0490	domain, Protein
RK54_RS03450	COG0471	metal ion transport
RK54_RS03460	COG0436	Aminotransferase
RK54_RS03470	COG0583	DNA-binding transcription factor activity
RK54_RS03520	COG0839	Belongs to the complex I subunit 6 family
RK54_RS03530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RK54_RS03535	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RK54_RS03545	COG0835	chemotaxis
RK54_RS03545	COG0784	Response regulator, receiver
RK54_RS03555	COG2153	protein acetylation
RK54_RS03560	COG4575	ribosome binding
RK54_RS03565	COG1169	isochorismate synthase
RK54_RS03655	COG1414	Transcriptional regulator
RK54_RS03665	COG2271	Major facilitator Superfamily
RK54_RS03690	COG0247	lactate metabolic process
RK54_RS03700	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RK54_RS03705	COG2271	Major facilitator Superfamily
RK54_RS03710	COG0584	glycerophosphoryl diester phosphodiesterase
RK54_RS03715	COG0583	DNA-binding transcription factor activity
RK54_RS03720	COG2814	Major facilitator Superfamily
RK54_RS03725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RK54_RS03755	COG4948	Mandelate Racemase Muconate Lactonizing
RK54_RS03780	COG0642	Histidine kinase
RK54_RS03780	COG2198	Histidine kinase
RK54_RS03810	COG4615	Cyclic peptide transporter
RK54_RS03820	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
RK54_RS03820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RK54_RS03825	COG3062	negative regulation of establishment of protein localization
RK54_RS03835	COG0437	4 iron, 4 sulfur cluster binding
RK54_RS03840	COG0348	domain, Protein
RK54_RS03850	COG3043	anaerobic respiration
RK54_RS03855	COG3005	denitrification pathway
RK54_RS03865	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK54_RS03870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK54_RS03875	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK54_RS03885	COG1138	Cytochrome C-type biogenesis protein
RK54_RS03895	COG4235	cytochrome complex assembly
RK54_RS03895	COG3088	subunit of a heme lyase
RK54_RS03900	COG2197	response regulator
RK54_RS03920	COG5301	cellulose 1,4-beta-cellobiosidase activity
RK54_RS03940	COG1403	HNH endonuclease
RK54_RS04035	COG1061	Type III restriction enzyme res subunit
RK54_RS04045	COG2814	Major facilitator Superfamily
RK54_RS04055	COG4172	Belongs to the ABC transporter superfamily
RK54_RS04060	COG4239	(ABC) transporter, permease
RK54_RS04065	COG4174	ABC transporter (Permease)
RK54_RS04070	COG4166	transmembrane transport
RK54_RS04075	COG2200	EAL domain
RK54_RS04085	COG0791	NLP P60 protein
RK54_RS04095	COG0671	phosphoesterase, PA-phosphatase related
RK54_RS04100	COG0523	cobalamin synthesis protein
RK54_RS04135	COG1105	Belongs to the carbohydrate kinase PfkB family
RK54_RS04140	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
RK54_RS04140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK54_RS04140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK54_RS04150	COG2855	membrane
RK54_RS04155	COG0583	DNA-binding transcription factor activity
RK54_RS04160	COG0833	amino acid
RK54_RS04170	COG4771	TonB-dependent receptor
RK54_RS04175	COG2271	Major facilitator Superfamily
RK54_RS04180	COG0560	Phosphoserine phosphatase
RK54_RS04185	COG1760	l-serine dehydratase
RK54_RS04210	COG2311	Membrane
RK54_RS04240	COG0493	'glutamate synthase
RK54_RS04250	COG2949	membrane
RK54_RS04260	COG1346	cytolysis
RK54_RS04275	COG2271	Major facilitator Superfamily
RK54_RS04290	COG0625	glutathione transferase activity
RK54_RS04295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RK54_RS04300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RK54_RS04310	COG1538	Outer membrane efflux protein
RK54_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
RK54_RS04320	COG0586	Pfam SNARE associated Golgi protein
RK54_RS04335	COG1686	Belongs to the peptidase S11 family
RK54_RS04340	COG0277	FAD linked oxidase domain protein
RK54_RS04350	COG1732	Glycine betaine
RK54_RS04355	COG1174	glycine betaine transport
RK54_RS04360	COG1125	glycine betaine transport
RK54_RS04365	COG1174	glycine betaine transport
RK54_RS04380	COG3275	phosphorelay sensor kinase activity
RK54_RS04390	COG4807	Protein conserved in bacteria
RK54_RS04400	COG4808	Protein conserved in bacteria
RK54_RS04425	COG3121	Chaperone
RK54_RS04430	COG3188	usher protein
RK54_RS04435	COG3539	Fimbrial protein
RK54_RS04440	COG5455	response to cobalt ion
RK54_RS04455	COG2188	Transcriptional regulator
RK54_RS04460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK54_RS04465	COG1397	ADP-ribosylglycohydrolase
RK54_RS04470	COG2211	Major facilitator Superfamily
RK54_RS04475	COG1830	Aldolase
RK54_RS04500	COG0826	peptidase U32
RK54_RS04525	COG0745	RESPONSE REGULATOR receiver
RK54_RS04530	COG2205	protein histidine kinase activity
RK54_RS04560	COG0443	Heat shock 70 kDa protein
RK54_RS04570	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RK54_RS04575	COG3447	MASE1 domain protein
RK54_RS04575	COG5001	Diguanylate cyclase
RK54_RS04575	COG5002	protein histidine kinase activity
RK54_RS04590	COG2982	Protein involved in outer membrane biogenesis
RK54_RS04595	COG1253	flavin adenine dinucleotide binding
RK54_RS04620	COG0463	Glycosyl transferase, family 2
RK54_RS04625	COG1045	serine acetyltransferase
RK54_RS04630	COG0438	transferase activity, transferring glycosyl groups
RK54_RS04640	COG1216	Glycosyl transferase, family 2
RK54_RS04645	COG0110	maltose O-acetyltransferase activity
RK54_RS04650	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
RK54_RS04655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK54_RS04665	COG0297	glycogen (starch) synthase activity
RK54_RS04680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK54_RS04685	COG2244	polysaccharide biosynthetic process
RK54_RS04690	COG2327	Polysaccharide pyruvyl transferase
RK54_RS04855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK54_RS04860	COG0583	DNA-binding transcription factor activity
RK54_RS04870	COG0531	amino acid
RK54_RS04875	COG2925	Exonuclease
RK54_RS04920	COG1289	transmembrane transporter activity
RK54_RS04955	COG4656	Part of a membrane complex involved in electron transport
RK54_RS04960	COG1454	alcohol dehydrogenase
RK54_RS04960	COG1012	belongs to the aldehyde dehydrogenase family
RK54_RS04975	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RK54_RS04990	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RK54_RS05120	COG1122	ATPase activity
RK54_RS05155	COG0534	Mate efflux family protein
RK54_RS05185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RK54_RS05240	COG0582	viral genome integration into host DNA
RK54_RS05290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RK54_RS05300	COG1418	mRNA catabolic process
RK54_RS05305	COG0270	DNA (cytosine-5-)-methyltransferase activity
RK54_RS05310	COG3727	T/G mismatch-specific endonuclease activity
RK54_RS05315	COG0697	spore germination
RK54_RS05320	COG2354	Protein conserved in bacteria
RK54_RS05325	COG5475	Uncharacterized small protein (DUF2158)
RK54_RS05430	COG0425	Belongs to the sulfur carrier protein TusA family
RK54_RS05485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK54_RS05495	COG0765	amino acid transport
RK54_RS05500	COG1126	abc transporter atp-binding protein
RK54_RS05505	COG2197	response regulator
RK54_RS05520	COG2197	response regulator
RK54_RS05565	COG3318	Belongs to the UPF0149 family
RK54_RS05565	COG3012	SEC-C Motif Domain Protein
RK54_RS05570	COG0814	amino acid
RK54_RS05580	COG1528	Iron-storage protein
RK54_RS05595	COG1528	Iron-storage protein
RK54_RS05700	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RK54_RS05715	COG3102	Protein conserved in bacteria
RK54_RS05740	COG3788	relative of glutathione S-transferase, MAPEG superfamily
RK54_RS05745	COG1801	Protein of unknown function DUF72
RK54_RS05750	COG1335	isochorismatase
RK54_RS05760	COG0494	nUDIX hydrolase
RK54_RS05795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK54_RS05805	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
RK54_RS05810	COG0739	heme binding
RK54_RS05820	COG1560	Kdo2-lipid A biosynthetic process
RK54_RS05830	COG1737	Transcriptional regulator
RK54_RS05840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RK54_RS05845	COG0129	dihydroxy-acid dehydratase activity
RK54_RS05850	COG0800	Aldolase
RK54_RS05860	COG3141	response to X-ray
RK54_RS05870	COG2979	Protein of unknown function (DUF533)
RK54_RS05875	COG1770	oligopeptidase
RK54_RS05880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RK54_RS05885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RK54_RS05895	COG2372	response to copper ion
RK54_RS05900	COG1276	copper resistance
RK54_RS05920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RK54_RS05975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RK54_RS06030	COG0454	-acetyltransferase
RK54_RS06040	COG5562	phage envelope protein
RK54_RS06075	COG3008	intermembrane lipid transfer
RK54_RS06080	COG2995	paraquat-inducible protein a
RK54_RS06085	COG1956	GAF domain-containing protein
RK54_RS06105	COG2814	Major facilitator Superfamily
RK54_RS06110	COG1414	Transcriptional regulator
RK54_RS06140	COG0768	penicillin binding
RK54_RS06145	COG2226	methyltransferase
RK54_RS06165	COG3716	PTS system mannose fructose sorbose family IID component
RK54_RS06170	COG3715	PTS system
RK54_RS06175	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS06175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK54_RS06185	COG1253	flavin adenine dinucleotide binding
RK54_RS06190	COG2200	EAL domain
RK54_RS06195	COG1760	l-serine dehydratase
RK54_RS06215	COG0251	oxidation-reduction process
RK54_RS06220	COG1199	ATP-dependent helicase activity
RK54_RS06230	COG3065	identical protein binding
RK54_RS06245	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
RK54_RS06255	COG2894	cell division
RK54_RS06270	COG0179	Fumarylacetoacetate (FAA) hydrolase
RK54_RS06310	COG2719	SpoVR family
RK54_RS06330	COG1619	proteins homologs of microcin C7 resistance protein MccF
RK54_RS06355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RK54_RS06365	COG1294	oxidase, subunit
RK54_RS06370	COG1271	oxidase subunit
RK54_RS06375	COG1773	rubredoxin
RK54_RS06380	COG1999	signal sequence binding
RK54_RS06385	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RK54_RS06390	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
RK54_RS06400	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RK54_RS06410	COG0012	GTP binding
RK54_RS06425	COG0659	secondary active sulfate transmembrane transporter activity
RK54_RS06475	COG0387	Pfam Sodium calcium exchanger
RK54_RS06480	COG4572	Cation transport regulator
RK54_RS06485	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
RK54_RS06490	COG4932	domain protein
RK54_RS06495	COG2197	response regulator
RK54_RS06500	COG3850	Histidine kinase
RK54_RS06510	COG2223	nitrite transmembrane transporter activity
RK54_RS06515	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RK54_RS06520	COG1140	nitrate reductase beta subunit
RK54_RS06525	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RK54_RS06530	COG2181	nitrate reductase activity
RK54_RS06580	COG0788	formyltetrahydrofolate deformylase activity
RK54_RS06590	COG1752	Esterase of the alpha-beta hydrolase superfamily
RK54_RS06595	COG0745	RESPONSE REGULATOR receiver
RK54_RS06600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RK54_RS06615	COG1012	belongs to the aldehyde dehydrogenase family
RK54_RS06615	COG1454	alcohol dehydrogenase
RK54_RS06620	COG2095	MarC family integral membrane protein
RK54_RS06655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RK54_RS06670	COG2350	Protein conserved in bacteria
RK54_RS06695	COG0727	PFAM Uncharacterised protein family (UPF0153)
RK54_RS06705	COG3546	catalase activity
RK54_RS06710	COG3685	Protein conserved in bacteria
RK54_RS06715	COG3685	Protein conserved in bacteria
RK54_RS06720	COG3729	General stress protein
RK54_RS06735	COG0135	phosphoribosylanthranilate isomerase activity
RK54_RS06735	COG0134	indole-3-glycerol-phosphate synthase activity
RK54_RS06760	COG0009	L-threonylcarbamoyladenylate synthase
RK54_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
RK54_RS06780	COG0616	signal peptide processing
RK54_RS06825	COG0671	phosphoesterase, PA-phosphatase related
RK54_RS06835	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
RK54_RS06840	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
RK54_RS06860	COG1349	DNA-binding transcription factor activity
RK54_RS06870	COG5001	Diguanylate cyclase
RK54_RS06885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RK54_RS06885	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RK54_RS06940	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RK54_RS06945	COG1842	Phage shock protein A
RK54_RS06955	COG1983	PspC domain protein
RK54_RS06965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RK54_RS06970	COG3106	COG3106 Predicted ATPase
RK54_RS06990	COG4948	Mandelate Racemase Muconate Lactonizing
RK54_RS06995	COG2866	Carboxypeptidase
RK54_RS07000	COG4166	transmembrane transport
RK54_RS07010	COG0583	DNA-binding transcription factor activity
RK54_RS07015	COG0656	L-ascorbic acid biosynthetic process
RK54_RS07020	COG1028	Short-chain dehydrogenase reductase Sdr
RK54_RS07025	COG1309	transcriptional regulator
RK54_RS07060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
RK54_RS07080	COG0668	transmembrane transport
RK54_RS07085	COG3182	Iron-regulated membrane protein
RK54_RS07105	COG2840	Smr protein MutS2
RK54_RS07115	COG0840	transmembrane signaling receptor activity
RK54_RS07130	COG0513	Belongs to the DEAD box helicase family
RK54_RS07145	COG2076	Multidrug Resistance protein
RK54_RS07160	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RK54_RS07160	COG0674	pyruvate-flavodoxin oxidoreductase activity
RK54_RS07160	COG1013	pyruvate-flavodoxin oxidoreductase activity
RK54_RS07160	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RK54_RS07170	COG3042	response to heat
RK54_RS07175	COG3187	Heat shock protein
RK54_RS07180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RK54_RS07185	COG2911	Protein conserved in bacteria
RK54_RS07195	COG3784	Protein of unknown function (DUF1318)
RK54_RS07210	COG1643	Atp-dependent helicase
RK54_RS07215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RK54_RS07220	COG3038	cytochrome b561
RK54_RS07225	COG0500	methyltransferase
RK54_RS07235	COG0765	amino acid transport
RK54_RS07245	COG0765	amino acid transport
RK54_RS07250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK54_RS07290	COG0840	transmembrane signaling receptor activity
RK54_RS07295	COG0583	DNA-binding transcription factor activity
RK54_RS07300	COG5383	Protein conserved in bacteria
RK54_RS07305	COG2272	Belongs to the type-B carboxylesterase lipase family
RK54_RS07315	COG2353	YceI-like domain
RK54_RS07320	COG1304	FMN binding
RK54_RS07330	COG1349	DNA-binding transcription factor activity
RK54_RS07335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RK54_RS07340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS07345	COG0434	BtpA family
RK54_RS07350	COG3775	system Galactitol-specific IIC component
RK54_RS07355	COG3414	Phosphotransferase system galactitol-specific IIB component
RK54_RS07365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK54_RS07370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RK54_RS07375	COG1275	C4-dicarboxylate transporter malic acid transport protein
RK54_RS07380	COG0500	methyltransferase
RK54_RS07390	COG3135	benzoate transporter
RK54_RS07395	COG1396	sequence-specific DNA binding
RK54_RS07400	COG0826	peptidase U32
RK54_RS07425	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RK54_RS07430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK54_RS07470	COG3238	Protein conserved in bacteria
RK54_RS07480	COG2130	NADP-dependent
RK54_RS07485	COG1802	Transcriptional regulator
RK54_RS07490	COG4772	TonB-dependent receptor
RK54_RS07530	COG2181	nitrate reductase activity
RK54_RS07535	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RK54_RS07540	COG1140	nitrate reductase beta subunit
RK54_RS07545	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RK54_RS07585	COG3383	formate dehydrogenase (NAD+) activity
RK54_RS07585	COG0243	molybdopterin cofactor binding
RK54_RS07590	COG0243	molybdopterin cofactor binding
RK54_RS07590	COG3383	formate dehydrogenase (NAD+) activity
RK54_RS07595	COG0437	4 iron, 4 sulfur cluster binding
RK54_RS07600	COG2864	formate dehydrogenase
RK54_RS07605	COG1064	alcohol dehydrogenase
RK54_RS07625	COG1764	response to oxidative stress
RK54_RS07640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RK54_RS07655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RK54_RS07660	COG1757	Na H antiporter
RK54_RS07665	COG1609	Transcriptional regulator
RK54_RS07725	COG0251	oxidation-reduction process
RK54_RS07730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RK54_RS07755	COG2271	Major facilitator Superfamily
RK54_RS07760	COG1063	alcohol dehydrogenase
RK54_RS07765	COG2186	Transcriptional regulator
RK54_RS07775	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RK54_RS07780	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
RK54_RS07805	COG1773	rubredoxin
RK54_RS07830	COG3781	membrane
RK54_RS07845	COG1012	belongs to the aldehyde dehydrogenase family
RK54_RS07850	COG0583	DNA-binding transcription factor activity
RK54_RS07885	COG2814	Major facilitator Superfamily
RK54_RS07895	COG3111	PFAM Bacterial OB fold (BOF) protein
RK54_RS07900	COG1546	Belongs to the CinA family
RK54_RS07905	COG3729	General stress protein
RK54_RS07920	COG4221	oxidoreductase activity
RK54_RS07925	COG1802	Transcriptional regulator
RK54_RS07935	COG0246	Mannitol dehydrogenase
RK54_RS07940	COG0477	Major facilitator Superfamily
RK54_RS07945	COG1063	alcohol dehydrogenase
RK54_RS07965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK54_RS07980	COG0243	molybdopterin cofactor binding
RK54_RS07985	COG0243	molybdopterin cofactor binding
RK54_RS07990	COG0437	4 iron, 4 sulfur cluster binding
RK54_RS07995	COG3302	dmso reductase anchor subunit
RK54_RS08035	COG1940	carbohydrate kinase activity
RK54_RS08045	COG0583	DNA-binding transcription factor activity
RK54_RS08050	COG2814	Major facilitator Superfamily
RK54_RS08060	COG3591	Belongs to the peptidase S1B family
RK54_RS08080	COG0628	permease
RK54_RS08085	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RK54_RS08090	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RK54_RS08100	COG0531	amino acid
RK54_RS08105	COG3136	membrane protein required for alginate biosynthesis
RK54_RS08110	COG0745	RESPONSE REGULATOR receiver
RK54_RS08120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RK54_RS08125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RK54_RS08130	COG2205	protein histidine kinase activity
RK54_RS08155	COG5339	Protein conserved in bacteria
RK54_RS08175	COG0673	inositol 2-dehydrogenase activity
RK54_RS08225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RK54_RS08235	COG0625	glutathione transferase activity
RK54_RS08255	COG3895	Periplasmic Protein
RK54_RS08280	COG1566	PFAM secretion protein HlyD family protein
RK54_RS08295	COG4989	oxidoreductase activity
RK54_RS08300	COG3313	Fe-S protein
RK54_RS08305	COG1309	transcriptional regulator
RK54_RS08310	COG1902	pentaerythritol trinitrate reductase activity
RK54_RS08330	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RK54_RS08335	COG0791	NLP P60 protein
RK54_RS08360	COG0583	DNA-binding transcription factor activity
RK54_RS08365	COG2814	Major facilitator Superfamily
RK54_RS08370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RK54_RS08375	COG0307	riboflavin synthase, alpha
RK54_RS08555	COG0789	Transcriptional regulator
RK54_RS08560	COG3272	Protein of unknown function (DUF1722)
RK54_RS08595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK54_RS08605	COG2267	carboxylic ester hydrolase activity
RK54_RS08610	COG0531	amino acid
RK54_RS08630	COG4238	major outer membrane lipoprotein
RK54_RS08635	COG1376	ErfK ybiS ycfS ynhG family protein
RK54_RS08650	COG0719	Fe-S assembly protein
RK54_RS08655	COG0396	ATPase activity
RK54_RS08660	COG0719	Fe-S assembly protein
RK54_RS08665	COG0316	Belongs to the HesB IscA family
RK54_RS08670	COG1823	symporter activity
RK54_RS08680	COG2050	protein possibly involved in aromatic compounds catabolism
RK54_RS08685	COG0277	FAD linked oxidase domain protein
RK54_RS08685	COG0247	lactate metabolic process
RK54_RS08690	COG0628	permease
RK54_RS08705	COG0738	Major facilitator superfamily
RK54_RS08710	COG2271	Major facilitator Superfamily
RK54_RS08725	COG4670	ketone body catabolic process
RK54_RS08730	COG1960	acyl-CoA dehydrogenase activity
RK54_RS08735	COG1917	Cupin 2, conserved barrel domain protein
RK54_RS08735	COG2207	Transcriptional regulator
RK54_RS08740	COG2086	electron transfer activity
RK54_RS08745	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RK54_RS08750	COG0644	oxidoreductase
RK54_RS08755	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
RK54_RS08760	COG0318	PFAM AMP-dependent synthetase and ligase
RK54_RS08765	COG0574	Belongs to the PEP-utilizing enzyme family
RK54_RS08765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RK54_RS08780	COG4256	Hemin uptake protein
RK54_RS08795	COG0791	NLP P60 protein
RK54_RS08805	COG0386	Belongs to the glutathione peroxidase family
RK54_RS08885	COG3137	Salt-induced outer membrane protein
RK54_RS08890	COG1105	Belongs to the carbohydrate kinase PfkB family
RK54_RS08900	COG3001	Fructosamine kinase
RK54_RS08910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK54_RS08915	COG1988	membrane-bound metal-dependent
RK54_RS08920	COG1823	symporter activity
RK54_RS08930	COG0753	catalase activity
RK54_RS08940	COG1486	melibiose metabolic process
RK54_RS08945	COG2169	Transcriptional regulator
RK54_RS08945	COG1917	Cupin 2, conserved barrel domain protein
RK54_RS08950	COG1447	Phosphotransferase system cellobiose-specific component IIA
RK54_RS08955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RK54_RS08960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RK54_RS08970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RK54_RS08980	COG0322	excinuclease ABC activity
RK54_RS08985	COG3678	ATP-independent chaperone mediated protein folding
RK54_RS09030	COG0494	nUDIX hydrolase
RK54_RS09055	COG0778	Nitroreductase
RK54_RS09060	COG0616	signal peptide processing
RK54_RS09065	COG0252	asparaginase activity
RK54_RS09070	COG1335	isochorismatase
RK54_RS09075	COG3139	Protein of unknown function (DUF1315)
RK54_RS09100	COG0656	L-ascorbic acid biosynthetic process
RK54_RS09105	COG0641	radical SAM
RK54_RS09110	COG3713	MltA-interacting MipA family protein
RK54_RS09115	COG2766	serine protein kinase
RK54_RS09130	COG2199	diguanylate cyclase activity
RK54_RS09135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RK54_RS09150	COG2207	Transcriptional regulator
RK54_RS09155	COG2807	transmembrane transport
RK54_RS09160	COG3189	MarR family transcriptional regulator
RK54_RS09170	COG3042	response to heat
RK54_RS09180	COG2261	transglycosylase associated protein
RK54_RS09200	COG3615	Tellurite resistance protein tehB
RK54_RS09215	COG1605	Chorismate mutase
RK54_RS09230	COG0789	Transcriptional regulator
RK54_RS09245	COG3443	Belongs to the bacterial solute-binding protein 9 family
RK54_RS09260	COG0668	transmembrane transport
RK54_RS09265	COG1124	(ABC) transporter
RK54_RS09295	COG3038	cytochrome b561
RK54_RS09305	COG0071	Belongs to the small heat shock protein (HSP20) family
RK54_RS09390	COG0538	isocitrate dehydrogenase activity
RK54_RS09420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RK54_RS09435	COG2850	peptidyl-arginine hydroxylation
RK54_RS09465	COG1177	transmembrane transport
RK54_RS09485	COG4591	ABC-type transport system involved in lipoprotein release permease component
RK54_RS09490	COG1136	(ABC) transporter
RK54_RS09495	COG4591	ABC-type transport system involved in lipoprotein release permease component
RK54_RS09500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RK54_RS09505	COG1388	LysM domain
RK54_RS09505	COG1376	ErfK ybiS ycfS ynhG family protein
RK54_RS09515	COG1309	transcriptional regulator
RK54_RS09520	COG3134	Outer membrane lipoprotein
RK54_RS09525	COG1252	NADH dehydrogenase
RK54_RS09550	COG5633	Lipoprotein
RK54_RS09555	COG0537	adenosine 5'-monophosphoramidase activity
RK54_RS09560	COG4773	Receptor
RK54_RS09570	COG0084	hydrolase, TatD family'
RK54_RS09575	COG0470	DNA polymerase III
RK54_RS09585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RK54_RS09590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RK54_RS09595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RK54_RS09660	COG1530	ribonuclease E activity
RK54_RS09755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK54_RS09765	COG2999	glutathione oxidoreductase activity
RK54_RS09805	COG3038	cytochrome b561
RK54_RS09820	COG1560	Kdo2-lipid A biosynthetic process
RK54_RS09840	COG5645	(Lipo)protein
RK54_RS09860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RK54_RS09920	COG3381	protein complex oligomerization
RK54_RS09950	COG0673	inositol 2-dehydrogenase activity
RK54_RS09955	COG2814	Major facilitator Superfamily
RK54_RS09980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RK54_RS09985	COG1737	Transcriptional regulator
RK54_RS09990	COG1702	phosphate starvation-inducible protein PhoH
RK54_RS10015	COG1309	transcriptional regulator
RK54_RS10020	COG3729	General stress protein
RK54_RS10040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK54_RS10045	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RK54_RS10045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RK54_RS10050	COG4232	protein-disulfide reductase activity
RK54_RS10105	COG3971	2-oxopent-4-enoate hydratase activity
RK54_RS10120	COG3384	dioxygenase
RK54_RS10125	COG1012	belongs to the aldehyde dehydrogenase family
RK54_RS10135	COG1846	Transcriptional regulator
RK54_RS10140	COG2368	4-hydroxyphenylacetate
RK54_RS10170	COG2205	protein histidine kinase activity
RK54_RS10225	COG0670	Belongs to the BI1 family
RK54_RS10245	COG1881	PFAM PEBP family protein
RK54_RS10260	COG1832	CoA-binding protein
RK54_RS10275	COG0210	DNA helicase
RK54_RS10280	COG3304	Inner membrane component domain
RK54_RS10285	COG1289	transmembrane transporter activity
RK54_RS10290	COG3070	regulator of competence-specific genes
RK54_RS10310	COG1067	ATP-dependent peptidase activity
RK54_RS10320	COG3130	regulation of translation
RK54_RS10325	COG3009	Protein conserved in bacteria
RK54_RS10330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RK54_RS10330	COG3008	intermembrane lipid transfer
RK54_RS10335	COG2995	paraquat-inducible protein a
RK54_RS10340	COG0488	(ABC) transporter
RK54_RS10350	COG3217	Mosc domain protein beta barrel domain protein
RK54_RS10350	COG0633	Ferredoxin
RK54_RS10365	COG0308	aminopeptidase N
RK54_RS10380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RK54_RS10405	COG5301	cellulose 1,4-beta-cellobiosidase activity
RK54_RS10530	COG3772	lysozyme
RK54_RS10560	COG0484	heat shock protein binding
RK54_RS10695	COG0582	viral genome integration into host DNA
RK54_RS10705	COG1115	amino acid carrier protein
RK54_RS10720	COG1522	sequence-specific DNA binding
RK54_RS10740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK54_RS10745	COG3108	Peptidase M15
RK54_RS10755	COG2989	Protein conserved in bacteria
RK54_RS10765	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
RK54_RS10775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RK54_RS10780	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RK54_RS10785	COG3173	Aminoglycoside phosphotransferase
RK54_RS10800	COG3214	Protein conserved in bacteria
RK54_RS10815	COG2333	competence protein COMEC
RK54_RS10815	COG0658	competence protein
RK54_RS10825	COG0539	negative regulation of cytoplasmic translation
RK54_RS10840	COG0501	Belongs to the peptidase M48B family
RK54_RS10855	COG2323	membrane
RK54_RS10860	COG1944	ATP diphosphatase activity
RK54_RS10865	COG2116	formate transmembrane transporter activity
RK54_RS10870	COG1882	Formate acetyltransferase
RK54_RS10885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RK54_RS10890	COG0531	amino acid
RK54_RS10900	COG3302	dmso reductase anchor subunit
RK54_RS10905	COG0437	4 iron, 4 sulfur cluster binding
RK54_RS10910	COG0243	molybdopterin cofactor binding
RK54_RS10920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RK54_RS10945	COG0492	ferredoxin-NADP+ reductase activity
RK54_RS10950	COG4988	ABC transporter
RK54_RS10955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RK54_RS10975	COG0583	DNA-binding transcription factor activity
RK54_RS10985	COG1335	isochorismatase
RK54_RS11020	COG0542	response to heat
RK54_RS11030	COG1278	Cold shock
RK54_RS11040	COG0577	efflux transmembrane transporter activity
RK54_RS11040	COG1136	(ABC) transporter
RK54_RS11045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RK54_RS11050	COG2990	Protein conserved in bacteria
RK54_RS11055	COG3593	DNA synthesis involved in DNA repair
RK54_RS11065	COG2431	L-lysine efflux transmembrane transporter activity
RK54_RS11075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RK54_RS11080	COG0028	Belongs to the TPP enzyme family
RK54_RS11085	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
RK54_RS11090	COG0702	epimerase
RK54_RS11095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK54_RS11100	COG3023	N-Acetylmuramoyl-L-alanine amidase
RK54_RS11115	COG1126	abc transporter atp-binding protein
RK54_RS11120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK54_RS11125	COG4215	(ABC) transporter
RK54_RS11130	COG4160	amino acid transport
RK54_RS11135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK54_RS11170	COG1177	transmembrane transport
RK54_RS11175	COG1176	ABC-type spermidine putrescine transport system, permease component I
RK54_RS11180	COG3842	ATPase activity
RK54_RS11185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RK54_RS11235	COG3226	Transcriptional regulator
RK54_RS11240	COG0738	Major facilitator superfamily
RK54_RS11245	COG0561	phosphatase activity
RK54_RS11250	COG2814	Major facilitator Superfamily
RK54_RS11255	COG0671	phosphoesterase, PA-phosphatase related
RK54_RS11260	COG1349	DNA-binding transcription factor activity
RK54_RS11265	COG1686	Belongs to the peptidase S11 family
RK54_RS11270	COG0625	glutathione transferase activity
RK54_RS11275	COG2133	pyrroloquinoline quinone binding
RK54_RS11285	COG2610	gluconate transmembrane transporter activity
RK54_RS11290	COG0583	DNA-binding transcription factor activity
RK54_RS11305	COG1960	acyl-CoA dehydrogenase activity
RK54_RS11325	COG2301	Belongs to the HpcH HpaI aldolase family
RK54_RS11375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RK54_RS11380	COG1882	Formate acetyltransferase
RK54_RS11385	COG0561	phosphatase activity
RK54_RS11400	COG0488	(ABC) transporter
RK54_RS11405	COG1376	ErfK ybiS ycfS ynhG family protein
RK54_RS11410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RK54_RS11425	COG2194	sulfuric ester hydrolase activity
RK54_RS11430	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RK54_RS11450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK54_RS11455	COG0765	amino acid transport
RK54_RS11460	COG1126	abc transporter atp-binding protein
RK54_RS11465	COG0668	transmembrane transport
RK54_RS11475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RK54_RS11485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RK54_RS11495	COG0513	Belongs to the DEAD box helicase family
RK54_RS11500	COG1309	transcriptional regulator
RK54_RS11510	COG1131	(ABC) transporter
RK54_RS11515	COG0842	Transport permease protein
RK54_RS11520	COG0842	Transport permease protein
RK54_RS11530	COG3568	Endonuclease Exonuclease Phosphatase
RK54_RS11535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RK54_RS11540	COG0392	lysyltransferase activity
RK54_RS11565	COG0670	Belongs to the BI1 family
RK54_RS11575	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RK54_RS11585	COG0521	Mo-molybdopterin cofactor biosynthetic process
RK54_RS11645	COG1881	PFAM PEBP family protein
RK54_RS11675	COG4677	pectinesterase activity
RK54_RS11685	COG0561	phosphatase activity
RK54_RS11695	COG4149	molybdate abc transporter
RK54_RS11700	COG0725	ABC transporter, periplasmic molybdate-binding protein
RK54_RS11710	COG2005	Transcriptional regulator
RK54_RS11710	COG3585	molybdate ion transport
RK54_RS11715	COG1119	ATPase activity
RK54_RS11740	COG2017	converts alpha-aldose to the beta-anomer
RK54_RS11755	COG1120	ATPase activity
RK54_RS11760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK54_RS11770	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
RK54_RS11785	COG0471	metal ion transport
RK54_RS11785	COG0490	domain, Protein
RK54_RS11790	COG0583	DNA-binding transcription factor activity
RK54_RS11795	COG0583	DNA-binding transcription factor activity
RK54_RS11805	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RK54_RS11805	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RK54_RS11810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RK54_RS11820	COG1230	cation diffusion facilitator family transporter
RK54_RS11865	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
RK54_RS11870	COG2885	chlorophyll binding
RK54_RS11880	COG3064	Membrane
RK54_RS11885	COG0848	biopolymer transport protein
RK54_RS11890	COG0811	peptide transport
RK54_RS11895	COG0824	Thioesterase
RK54_RS11900	COG3790	cyd operon protein YbgE
RK54_RS11905	COG4890	Cyd operon protein YbgT
RK54_RS11910	COG1294	oxidase, subunit
RK54_RS11915	COG1271	oxidase subunit
RK54_RS11925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RK54_RS11935	COG0508	dehydrogenase complex catalyzes the overall conversion of
RK54_RS11940	COG0567	Dehydrogenase, E1 component
RK54_RS11955	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
RK54_RS11980	COG3180	Ammonia monooxygenase
RK54_RS12005	COG1216	Glycosyl transferase, family 2
RK54_RS12050	COG0582	viral genome integration into host DNA
RK54_RS12065	COG1984	allophanate hydrolase subunit 2
RK54_RS12070	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RK54_RS12120	COG2205	protein histidine kinase activity
RK54_RS12125	COG0745	RESPONSE REGULATOR receiver
RK54_RS12130	COG1982	Orn Lys Arg decarboxylase major
RK54_RS12135	COG0531	amino acid
RK54_RS12145	COG0033	Phosphoglucomutase
RK54_RS12155	COG0596	Alpha beta hydrolase
RK54_RS12170	COG0735	belongs to the Fur family
RK54_RS12175	COG0583	DNA-binding transcription factor activity
RK54_RS12180	COG1053	succinate dehydrogenase
RK54_RS12225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RK54_RS12230	COG1846	Transcriptional regulator
RK54_RS12230	COG1940	carbohydrate kinase activity
RK54_RS12235	COG0647	UMP catabolic process
RK54_RS12240	COG0367	asparagine synthase
RK54_RS12285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RK54_RS12295	COG1702	phosphate starvation-inducible protein PhoH
RK54_RS12320	COG0765	amino acid transport
RK54_RS12325	COG0765	amino acid transport
RK54_RS12330	COG1126	abc transporter atp-binding protein
RK54_RS12345	COG0443	Heat shock 70 kDa protein
RK54_RS12350	COG2214	Heat shock protein DnaJ domain protein
RK54_RS12360	COG2214	Heat shock protein DnaJ domain protein
RK54_RS12375	COG2888	peptidyl-tyrosine sulfation
RK54_RS12380	COG3829	transcription factor binding
RK54_RS12380	COG3290	protein histidine kinase activity
RK54_RS12410	COG1466	dna polymerase III delta subunit
RK54_RS12430	COG0799	negative regulation of ribosome biogenesis
RK54_RS12440	COG0768	penicillin binding
RK54_RS12445	COG0772	Belongs to the SEDS family
RK54_RS12455	COG1686	Belongs to the peptidase S11 family
RK54_RS12470	COG0583	DNA-binding transcription factor activity
RK54_RS12485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RK54_RS12510	COG3069	C4-dicarboxylate transmembrane transporter activity
RK54_RS12515	COG4565	transcriptional regulatory protein
RK54_RS12520	COG3290	protein histidine kinase activity
RK54_RS12525	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
RK54_RS12535	COG2301	Belongs to the HpcH HpaI aldolase family
RK54_RS12540	COG3051	citrate lyase alpha subunit
RK54_RS12555	COG0471	metal ion transport
RK54_RS12560	COG3719	Belongs to the RNase T2 family
RK54_RS12570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RK54_RS12575	COG1063	alcohol dehydrogenase
RK54_RS12595	COG0243	molybdopterin cofactor binding
RK54_RS12615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RK54_RS12625	COG0583	DNA-binding transcription factor activity
RK54_RS12630	COG3969	phosphoadenosine phosphosulfate
RK54_RS12635	COG1475	DNA binding
RK54_RS12640	COG0436	Aminotransferase
RK54_RS12645	COG0371	Dehydrogenase
RK54_RS12650	COG2879	small protein
RK54_RS12655	COG1966	Carbon starvation protein
RK54_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
RK54_RS12670	COG1535	isochorismatase
RK54_RS12670	COG3433	isochorismatase activity
RK54_RS12675	COG1021	2,3-dihydroxybenzoate-AMP ligase
RK54_RS12680	COG1169	isochorismate synthase
RK54_RS12685	COG4592	Periplasmic binding protein
RK54_RS12695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK54_RS12700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK54_RS12705	COG1120	ATPase activity
RK54_RS12710	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
RK54_RS12715	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RK54_RS12715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RK54_RS12720	COG3251	PFAM MbtH domain protein
RK54_RS12725	COG2382	esterase
RK54_RS12730	COG4771	TonB-dependent receptor
RK54_RS12735	COG2977	Belongs to the P-Pant transferase superfamily
RK54_RS12760	COG2315	Protein conserved in bacteria
RK54_RS12785	COG3716	PTS system mannose fructose sorbose family IID component
RK54_RS12795	COG2222	sugar isomerase
RK54_RS12800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RK54_RS12800	COG3933	PFAM sigma-54 factor interaction domain-containing protein
RK54_RS12815	COG0668	transmembrane transport
RK54_RS12820	COG1113	amino acid transport
RK54_RS12830	COG3059	membrane
RK54_RS12845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK54_RS12850	COG2207	Transcriptional regulator
RK54_RS12855	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK54_RS12860	COG5002	protein histidine kinase activity
RK54_RS12870	COG2246	polysaccharide biosynthetic process
RK54_RS12875	COG0463	Glycosyl transferase, family 2
RK54_RS12890	COG0582	viral genome integration into host DNA
RK54_RS12965	COG2501	S4 domain
RK54_RS12970	COG1988	membrane-bound metal-dependent
RK54_RS12990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RK54_RS13005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RK54_RS13010	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RK54_RS13015	COG0549	Belongs to the carbamate kinase family
RK54_RS13025	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RK54_RS13030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RK54_RS13035	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RK54_RS13040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RK54_RS13045	COG3257	ureidoglycine aminohydrolase activity
RK54_RS13050	COG1929	Belongs to the glycerate kinase type-1 family
RK54_RS13055	COG2233	PERMEase
RK54_RS13065	COG1953	Uracil, thiamine, allantoin
RK54_RS13075	COG2084	Dehydrogenase
RK54_RS13080	COG3622	Belongs to the hyi family
RK54_RS13085	COG3960	tartronate-semialdehyde synthase activity
RK54_RS13120	COG1464	Belongs to the NlpA lipoprotein family
RK54_RS13130	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RK54_RS13135	COG4181	ATPase activity
RK54_RS13140	COG2755	lipolytic protein G-D-S-L family
RK54_RS13145	COG0300	oxidoreductase activity
RK54_RS13150	COG3118	belongs to the thioredoxin family
RK54_RS13155	COG0390	transport system, permease component
RK54_RS13160	COG4619	ABC transporter
RK54_RS13165	COG0330	HflC and HflK could
RK54_RS13170	COG1585	Membrane protein implicated in regulation of membrane protease activity
RK54_RS13190	COG3735	TraB family
RK54_RS13205	COG2223	nitrite transmembrane transporter activity
RK54_RS13210	COG4651	solute:proton antiporter activity
RK54_RS13210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RK54_RS13215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK54_RS13275	COG2832	Protein of unknown function (DUF454)
RK54_RS13280	COG3923	Primosomal replication protein n
RK54_RS13300	COG3264	Mechanosensitive ion channel
RK54_RS13300	COG1196	nuclear chromosome segregation
RK54_RS13305	COG1309	transcriptional regulator
RK54_RS13310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RK54_RS13315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK54_RS13330	COG0110	maltose O-acetyltransferase activity
RK54_RS13350	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RK54_RS13360	COG3695	enzyme binding
RK54_RS13365	COG3126	Type III secretion system lipoprotein chaperone (YscW)
RK54_RS13370	COG1946	Acyl-CoA thioesterase
RK54_RS13375	COG0004	ammonium transporteR
RK54_RS13380	COG0347	Belongs to the P(II) protein family
RK54_RS13390	COG1132	(ABC) transporter
RK54_RS13395	COG1132	(ABC) transporter
RK54_RS13400	COG1522	sequence-specific DNA binding
RK54_RS13415	COG4533	DNA binding
RK54_RS13425	COG0824	Thioesterase
RK54_RS13430	COG1555	photosystem II stabilization
RK54_RS13435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RK54_RS13445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RK54_RS13470	COG0271	Belongs to the BolA IbaG family
RK54_RS13480	COG3056	Lipoprotein
RK54_RS13485	COG2223	nitrite transmembrane transporter activity
RK54_RS13490	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RK54_RS13495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RK54_RS13500	COG1845	cytochrome c oxidase, subunit III
RK54_RS13505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RK54_RS13525	COG2814	Major facilitator Superfamily
RK54_RS13555	COG2188	Transcriptional regulator
RK54_RS13590	COG0142	geranyltranstransferase activity
RK54_RS13600	COG0667	Aldo Keto reductase
RK54_RS13605	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RK54_RS13610	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RK54_RS13625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK54_RS13625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK54_RS13635	COG4238	major outer membrane lipoprotein
RK54_RS13670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK54_RS13680	COG1862	Preprotein translocase
RK54_RS13705	COG0450	alkyl hydroperoxide reductase
RK54_RS13710	COG0366	Alpha amylase catalytic
RK54_RS13725	COG5002	protein histidine kinase activity
RK54_RS13735	COG0420	3'-5' exonuclease activity
RK54_RS13740	COG0419	ATPase involved in DNA repair
RK54_RS13745	COG2814	Major facilitator Superfamily
RK54_RS13750	COG1940	carbohydrate kinase activity
RK54_RS13765	COG4126	flavin adenine dinucleotide binding
RK54_RS13785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RK54_RS13790	COG3706	GGDEF domain
RK54_RS13835	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
RK54_RS13845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RK54_RS13860	COG0113	porphobilinogen synthase activity
RK54_RS13870	COG2079	MmgE PrpD family protein
RK54_RS13895	COG1280	lysine exporter protein (LysE YggA)
RK54_RS13915	COG1294	oxidase, subunit
RK54_RS13920	COG1271	oxidase subunit
RK54_RS13940	COG2814	Major facilitator Superfamily
RK54_RS13950	COG0789	Transcriptional regulator
RK54_RS14005	COG2200	EAL domain
RK54_RS14030	COG3539	Fimbrial protein
RK54_RS14035	COG3121	Chaperone
RK54_RS14040	COG3188	usher protein
RK54_RS14075	COG0179	Fumarylacetoacetate (FAA) hydrolase
RK54_RS14090	COG2814	Major facilitator Superfamily
RK54_RS14115	COG0582	viral genome integration into host DNA
RK54_RS14125	COG2246	polysaccharide biosynthetic process
RK54_RS14130	COG0463	Glycosyl transferase, family 2
RK54_RS14250	COG3772	lysozyme
RK54_RS14265	COG0484	heat shock protein binding
RK54_RS14315	COG0305	Participates in initiation and elongation during chromosome replication
RK54_RS14440	COG0582	viral genome integration into host DNA
RK54_RS14480	COG2195	Cleaves the N-terminal amino acid of tripeptides
RK54_RS14485	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RK54_RS14490	COG1690	Belongs to the RtcB family
RK54_RS14500	COG3034	peptidoglycan biosynthetic process
RK54_RS14505	COG0121	glutamine amidotransferase
RK54_RS14520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RK54_RS14550	COG1522	sequence-specific DNA binding
RK54_RS14610	COG3209	COG3209 Rhs family protein
RK54_RS14670	COG2885	chlorophyll binding
RK54_RS14670	COG3047	cAMP biosynthetic process
RK54_RS14775	COG2226	methyltransferase
RK54_RS14785	COG0741	lytic transglycosylase activity
RK54_RS14785	COG1388	LysM domain
RK54_RS14790	COG2226	methyltransferase
RK54_RS14800	COG2814	Major facilitator Superfamily
RK54_RS14805	COG0583	DNA-binding transcription factor activity
RK54_RS14845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RK54_RS14870	COG1720	tRNA m6t6A37 methyltransferase activity
RK54_RS14880	COG3015	lipoprotein NlpE involved in copper resistance
RK54_RS14885	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RK54_RS14900	COG4568	rho-dependent transcription termination
RK54_RS14910	COG0346	lactoylglutathione lyase activity
RK54_RS14915	COG1982	Orn Lys Arg decarboxylase major
RK54_RS14975	COG0575	Belongs to the CDS family
RK54_RS15040	COG0477	Major facilitator Superfamily
RK54_RS15050	COG3835	regulator
RK54_RS15075	COG2860	membrane
RK54_RS15105	COG3539	Fimbrial protein
RK54_RS15110	COG3539	Fimbrial protein
RK54_RS15115	COG3121	Chaperone
RK54_RS15120	COG3188	usher protein
RK54_RS15140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK54_RS15145	COG1120	ATPase activity
RK54_RS15150	COG4774	siderophore transport
RK54_RS15155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RK54_RS15160	COG1643	Atp-dependent helicase
RK54_RS15165	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RK54_RS15190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RK54_RS15215	COG3121	Chaperone
RK54_RS15220	COG3188	usher protein
RK54_RS15225	COG3539	Fimbrial protein
RK54_RS15245	COG0726	polysaccharide deacetylase
RK54_RS15250	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS15270	COG3539	Fimbrial protein
RK54_RS15275	COG0842	Transport permease protein
RK54_RS15280	COG1131	(ABC) transporter
RK54_RS15285	COG0288	reversible hydration of carbon dioxide
RK54_RS15295	COG4993	Dehydrogenase
RK54_RS15300	COG2132	Multicopper oxidase
RK54_RS15320	COG1349	DNA-binding transcription factor activity
RK54_RS15395	COG3064	Membrane
RK54_RS15410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK54_RS15415	COG0508	dehydrogenase complex catalyzes the overall conversion of
RK54_RS15420	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RK54_RS15435	COG2211	Major facilitator Superfamily
RK54_RS15440	COG3940	Belongs to the glycosyl hydrolase 43 family
RK54_RS15445	COG3725	Membrane protein required for beta-lactamase induction
RK54_RS15465	COG4969	Belongs to the N-Me-Phe pilin family
RK54_RS15470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RK54_RS15475	COG1459	type II secretion system
RK54_RS15510	COG0494	nUDIX hydrolase
RK54_RS15530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RK54_RS15535	COG0849	cell division
RK54_RS15560	COG0772	Belongs to the SEDS family
RK54_RS15575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RK54_RS15580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RK54_RS15585	COG0768	penicillin binding
RK54_RS15675	COG0586	Pfam SNARE associated Golgi protein
RK54_RS15715	COG0417	DNA replication proofreading
RK54_RS15800	COG3119	arylsulfatase activity
RK54_RS15825	COG2271	Major facilitator Superfamily
RK54_RS15835	COG0644	oxidoreductase
RK54_RS15890	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RK54_RS15985	COG1047	Peptidyl-prolyl cis-trans
RK54_RS16000	COG0196	riboflavin kinase activity
RK54_RS16025	COG0583	DNA-binding transcription factor activity
RK54_RS16050	COG0641	radical SAM
RK54_RS16055	COG3119	arylsulfatase activity
RK54_RS16090	COG3121	Chaperone
RK54_RS16095	COG3539	Fimbrial protein
RK54_RS16110	COG3188	usher protein
RK54_RS16115	COG3121	Chaperone
RK54_RS16175	COG4735	regulation of single-species biofilm formation
RK54_RS16180	COG1584	GPR1 FUN34 yaaH family protein
RK54_RS16185	COG0521	Mo-molybdopterin cofactor biosynthetic process
RK54_RS16195	COG1115	amino acid carrier protein
RK54_RS16205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RK54_RS16215	COG0460	homoserine dehydrogenase
RK54_RS16215	COG0527	aspartate kinase activity
RK54_RS16225	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
RK54_RS16235	COG0745	RESPONSE REGULATOR receiver
RK54_RS16255	COG3121	Chaperone
RK54_RS16275	COG4452	Inner membrane protein CreD
RK54_RS16280	COG2205	protein histidine kinase activity
RK54_RS16285	COG0745	RESPONSE REGULATOR receiver
RK54_RS16290	COG3045	CreA protein
RK54_RS16295	COG2207	Transcriptional regulator
RK54_RS16295	COG3708	Transcriptional regulator
RK54_RS16330	COG0488	(ABC) transporter
RK54_RS16345	COG0560	Phosphoserine phosphatase
RK54_RS16355	COG3726	membrane protein affecting hemolysin expression
RK54_RS16370	COG3539	Fimbrial protein
RK54_RS16375	COG3121	Chaperone
RK54_RS16380	COG3188	usher protein
RK54_RS16410	COG1328	CTP reductase activity
RK54_RS16415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RK54_RS16420	COG0084	hydrolase, TatD family'
RK54_RS16425	COG4667	esterase of the alpha-beta hydrolase superfamily
RK54_RS16435	COG2823	Periplasmic or secreted lipoprotein
RK54_RS16445	COG1011	Hydrolase
RK54_RS16455	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
RK54_RS16485	COG3706	GGDEF domain
RK54_RS16490	COG4114	ferric iron reductase
RK54_RS16495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RK54_RS16500	COG2197	response regulator
RK54_RS16505	COG2197	response regulator
RK54_RS16510	COG2966	Psort location CytoplasmicMembrane, score
RK54_RS16525	COG1484	DNA-dependent DNA replication
RK54_RS16545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RK54_RS16550	COG3716	PTS system mannose fructose sorbose family IID component
RK54_RS16555	COG3715	PTS system
RK54_RS16560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK54_RS16575	COG0840	transmembrane signaling receptor activity
RK54_RS16580	COG1966	Carbon starvation protein
RK54_RS16585	COG2879	small protein
RK54_RS16590	COG0523	cobalamin synthesis protein
RK54_RS16605	COG1715	Restriction endonuclease
RK54_RS16610	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
RK54_RS16645	COG1012	belongs to the aldehyde dehydrogenase family
RK54_RS16650	COG5464	transposase or invertase
RK54_RS16650	COG5464	transposase or invertase
RK54_RS16660	COG2733	membrane
RK54_RS16665	COG0477	Major facilitator Superfamily
RK54_RS16670	COG3366	ferrous iron transmembrane transporter activity
RK54_RS16675	COG0700	Nucleoside recognition
RK54_RS16680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RK54_RS16685	COG0583	DNA-binding transcription factor activity
RK54_RS16710	COG2186	Transcriptional regulator
RK54_RS16720	COG0412	Dienelactone hydrolase
RK54_RS16760	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RK54_RS16795	COG0210	DNA helicase
RK54_RS16800	COG1111	helicase
RK54_RS16800	COG1205	dead DEAH box helicase
RK54_RS16810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RK54_RS16825	COG0582	viral genome integration into host DNA
RK54_RS16835	COG1064	alcohol dehydrogenase
RK54_RS16840	COG3265	gluconokinase activity
RK54_RS16845	COG1063	alcohol dehydrogenase
RK54_RS16850	COG1028	Short-chain dehydrogenase reductase Sdr
RK54_RS16855	COG2610	gluconate transmembrane transporter activity
RK54_RS16860	COG1609	Transcriptional regulator
RK54_RS16865	COG0795	lipopolysaccharide-transporting ATPase activity
RK54_RS16870	COG0795	lipopolysaccharide-transporting ATPase activity
RK54_RS16890	COG2927	DNA polymerase III (CHI subunit)
RK54_RS16940	COG2731	YhcH YjgK YiaL family protein
RK54_RS16965	COG1288	antiporter activity
RK54_RS16970	COG1438	arginine binding
RK54_RS17015	COG1263	PTS System
RK54_RS17015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK54_RS17020	COG0366	Alpha amylase catalytic
RK54_RS17035	COG2026	Addiction module toxin, RelE StbE family
RK54_RS17040	COG3077	Addiction module antitoxin, RelB DinJ family
RK54_RS17045	COG3711	transcriptional antiterminator
RK54_RS17045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS17060	COG3964	amidohydrolase
RK54_RS17095	COG0312	modulator of DNA gyrase
RK54_RS17105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RK54_RS17120	COG3964	amidohydrolase
RK54_RS17125	COG2271	Major facilitator Superfamily
RK54_RS17130	COG2105	PFAM AIG2 family protein
RK54_RS17150	COG1253	flavin adenine dinucleotide binding
RK54_RS17165	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
RK54_RS17185	COG1733	regulation of RNA biosynthetic process
RK54_RS17190	COG0702	epimerase
RK54_RS17195	COG0697	spore germination
RK54_RS17205	COG1113	amino acid transport
RK54_RS17210	COG0545	Peptidyl-prolyl cis-trans isomerase
RK54_RS17220	COG3061	Opacity-associated protein A
RK54_RS17235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RK54_RS17290	COG3037	sugar-specific permease SgaT UlaA
RK54_RS17305	COG1073	alpha beta
RK54_RS17310	COG3650	response to hydrogen peroxide
RK54_RS17320	COG1960	acyl-CoA dehydrogenase activity
RK54_RS17325	COG0754	glutathionylspermidine amidase activity
RK54_RS17330	COG5463	Belongs to the UPF0441 family
RK54_RS17335	COG3766	membrane
RK54_RS17350	COG1842	Phage shock protein A
RK54_RS17355	COG3789	protein conserved in bacteria
RK54_RS17370	COG0557	exoribonuclease II activity
RK54_RS17385	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
RK54_RS17390	COG0330	HflC and HflK could
RK54_RS17395	COG0330	HflC and HflK could
RK54_RS17400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RK54_RS17425	COG0802	atpase or kinase
RK54_RS17430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RK54_RS17430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RK54_RS17455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK54_RS17475	COG3264	Mechanosensitive ion channel
RK54_RS17475	COG1511	domain protein
RK54_RS17495	COG1053	succinate dehydrogenase
RK54_RS17500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RK54_RS17530	COG5510	response to toxic substance
RK54_RS17575	COG0531	amino acid
RK54_RS17580	COG3030	protein affecting phage T7 exclusion by the F plasmid
RK54_RS17585	COG1027	Aspartate ammonia-lyase
RK54_RS17590	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RK54_RS17605	COG1309	transcriptional regulator
RK54_RS17655	COG2197	response regulator
RK54_RS17660	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
RK54_RS17675	COG3381	protein complex oligomerization
RK54_RS17680	COG3302	dmso reductase anchor subunit
RK54_RS17685	COG0437	4 iron, 4 sulfur cluster binding
RK54_RS17690	COG0243	molybdopterin cofactor binding
RK54_RS17695	COG3290	protein histidine kinase activity
RK54_RS17700	COG4565	transcriptional regulatory protein
RK54_RS17710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RK54_RS17715	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RK54_RS17715	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RK54_RS17730	COG2169	Transcriptional regulator
RK54_RS17735	COG1982	Orn Lys Arg decarboxylase major
RK54_RS17740	COG2207	Transcriptional regulator
RK54_RS17745	COG0531	amino acid
RK54_RS17775	COG2824	Alkylphosphonate utilization operon protein PhnA
RK54_RS17780	COG2764	glyoxalase bleomycin resistance protein dioxygenase
RK54_RS17800	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
RK54_RS17805	COG1301	dicarboxylic acid transport
RK54_RS17810	COG4235	cytochrome complex assembly
RK54_RS17815	COG3088	subunit of a heme lyase
RK54_RS17820	COG1138	Cytochrome C-type biogenesis protein
RK54_RS17825	COG3301	Polysulphide reductase, NrfD
RK54_RS17830	COG0437	4 iron, 4 sulfur cluster binding
RK54_RS17835	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
RK54_RS17850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK54_RS17860	COG3162	membrane
RK54_RS17870	COG1346	cytolysis
RK54_RS17875	COG1380	Effector of murein hydrolase LrgA
RK54_RS17880	COG0583	DNA-binding transcription factor activity
RK54_RS17885	COG0025	NhaP-type Na H and K H
RK54_RS17895	COG2252	PERMEase
RK54_RS17920	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RK54_RS17990	COG2315	Protein conserved in bacteria
RK54_RS18045	COG0735	belongs to the Fur family
RK54_RS18060	COG0534	Mate efflux family protein
RK54_RS18070	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RK54_RS18125	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RK54_RS18150	COG0527	aspartate kinase activity
RK54_RS18230	COG2246	polysaccharide biosynthetic process
RK54_RS18260	COG5301	cellulose 1,4-beta-cellobiosidase activity
RK54_RS18300	COG3122	Protein conserved in bacteria
RK54_RS18345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RK54_RS18390	COG0151	Belongs to the GarS family
RK54_RS18455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RK54_RS18460	COG2104	thiamine diphosphate biosynthetic process
RK54_RS18530	COG0250	Participates in transcription elongation, termination and antitermination
RK54_RS18645	COG0583	DNA-binding transcription factor activity
RK54_RS18690	COG2207	Transcriptional regulator
RK54_RS18700	COG0371	Dehydrogenase
RK54_RS18705	COG3738	Protein conserved in bacteria
RK54_RS18720	COG0737	Belongs to the 5'-nucleotidase family
RK54_RS18735	COG0668	transmembrane transport
RK54_RS18740	COG0460	homoserine dehydrogenase
RK54_RS18740	COG0527	aspartate kinase activity
RK54_RS18745	COG0626	cystathionine gamma-synthase activity
RK54_RS18770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RK54_RS18775	COG1609	Transcriptional regulator
RK54_RS18780	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RK54_RS18795	COG1575	Belongs to the MenA family. Type 1 subfamily
RK54_RS18810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RK54_RS18820	COG1494	fructose-1,6-bisphosphatase
RK54_RS18830	COG3152	Membrane
RK54_RS18885	COG1070	Carbohydrate kinase
RK54_RS18895	COG2134	cdp-diacylglycerol pyrophosphatase
RK54_RS18905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK54_RS18920	COG2211	Major facilitator Superfamily
RK54_RS18945	COG3678	ATP-independent chaperone mediated protein folding
RK54_RS18950	COG0745	RESPONSE REGULATOR receiver
RK54_RS18955	COG2205	protein histidine kinase activity
RK54_RS18970	COG2258	MOSC domain
RK54_RS18975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RK54_RS18985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RK54_RS19030	COG1454	alcohol dehydrogenase
RK54_RS19045	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RK54_RS19070	COG3383	formate dehydrogenase (NAD+) activity
RK54_RS19070	COG0243	molybdopterin cofactor binding
RK54_RS19075	COG3383	formate dehydrogenase (NAD+) activity
RK54_RS19075	COG0243	molybdopterin cofactor binding
RK54_RS19080	COG0437	4 iron, 4 sulfur cluster binding
RK54_RS19085	COG2864	formate dehydrogenase
RK54_RS19100	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
RK54_RS19110	COG4680	protein conserved in bacteria
RK54_RS19115	COG5499	transcription regulator containing HTH domain
RK54_RS19120	COG0456	acetyltransferase
RK54_RS19135	COG1011	Hydrolase
RK54_RS19140	COG1349	DNA-binding transcription factor activity
RK54_RS19145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK54_RS19155	COG3684	Belongs to the aldolase LacD family
RK54_RS19165	COG2017	converts alpha-aldose to the beta-anomer
RK54_RS19175	COG1501	Belongs to the glycosyl hydrolase 31 family
RK54_RS19185	COG2211	Major facilitator Superfamily
RK54_RS19265	COG0204	Acyl-transferase
RK54_RS19280	COG3084	Protein conserved in bacteria
RK54_RS19290	COG1763	Mo-molybdopterin cofactor biosynthetic process
RK54_RS19335	COG1739	Uncharacterized protein family UPF0029
RK54_RS19380	COG0805	protein transport
RK54_RS19425	COG0641	radical SAM
RK54_RS19445	COG0561	phosphatase activity
RK54_RS19450	COG2267	carboxylic ester hydrolase activity
RK54_RS19460	COG1280	lysine exporter protein (LysE YggA)
RK54_RS19510	COG1011	Hydrolase
RK54_RS19515	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RK54_RS19570	COG2959	enzyme of heme biosynthesis
RK54_RS19575	COG3071	HemY protein
RK54_RS19620	COG2244	polysaccharide biosynthetic process
RK54_RS19625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RK54_RS19630	COG0456	acetyltransferase
RK54_RS19635	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RK54_RS19635	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RK54_RS19640	COG1088	dTDP-glucose 4,6-dehydratase activity
RK54_RS19675	COG3118	belongs to the thioredoxin family
RK54_RS19700	COG3201	nicotinamide mononucleotide transporter
RK54_RS19750	COG3978	acetolactate synthase activity
RK54_RS19810	COG2186	Transcriptional regulator
RK54_RS19815	COG0477	Major facilitator Superfamily
RK54_RS19820	COG1609	Transcriptional regulator
RK54_RS19825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK54_RS19835	COG1172	Belongs to the binding-protein-dependent transport system permease family
RK54_RS19870	COG1522	sequence-specific DNA binding
RK54_RS19875	COG0716	FMN binding
RK54_RS19895	COG3312	ion transport
RK54_RS19960	COG4533	DNA binding
RK54_RS19965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RK54_RS19970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK54_RS19970	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
RK54_RS19970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK54_RS19975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RK54_RS19980	COG0573	inorganic phosphate transmembrane transporter activity
RK54_RS19985	COG0581	inorganic phosphate transmembrane transporter activity
RK54_RS19995	COG0704	Plays a role in the regulation of phosphate uptake
RK54_RS20000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK54_RS20005	COG2252	PERMEase
RK54_RS20010	COG0431	NADPH-dependent FMN reductase
RK54_RS20015	COG2091	lysine biosynthetic process via aminoadipic acid
RK54_RS20080	COG4948	Mandelate Racemase Muconate Lactonizing
RK54_RS20085	COG2271	Major facilitator Superfamily
RK54_RS20090	COG0561	phosphatase activity
RK54_RS20095	COG2186	Transcriptional regulator
RK54_RS20100	COG3734	2-keto-3-deoxy-galactonokinase
RK54_RS20105	COG0800	Aldolase
RK54_RS20115	COG2271	Major facilitator Superfamily
RK54_RS20120	COG2205	protein histidine kinase activity
RK54_RS20120	COG2198	Histidine kinase
RK54_RS20120	COG0784	Response regulator, receiver
RK54_RS20125	COG1879	ABC-type sugar transport system periplasmic component
RK54_RS20130	COG0745	RESPONSE REGULATOR receiver
RK54_RS20135	COG3005	denitrification pathway
RK54_RS20150	COG1858	cytochrome C peroxidase
RK54_RS20155	COG4133	protoheme IX ABC transporter activity
RK54_RS20160	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK54_RS20165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK54_RS20170	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK54_RS20180	COG1138	Cytochrome C-type biogenesis protein
RK54_RS20190	COG4235	cytochrome complex assembly
RK54_RS20190	COG3088	subunit of a heme lyase
RK54_RS20195	COG0823	Involved in the tonB-independent uptake of proteins
RK54_RS20200	COG5645	(Lipo)protein
RK54_RS20220	COG2149	membrane
RK54_RS20230	COG0641	radical SAM
RK54_RS20240	COG2610	gluconate transmembrane transporter activity
RK54_RS20245	COG0583	DNA-binding transcription factor activity
RK54_RS20255	COG2814	Major facilitator Superfamily
RK54_RS20285	COG0028	Belongs to the TPP enzyme family
RK54_RS20290	COG0440	acetolactate synthase activity
RK54_RS20295	COG1349	DNA-binding transcription factor activity
RK54_RS20305	COG0738	Major facilitator superfamily
RK54_RS20340	COG2188	Transcriptional regulator
RK54_RS20345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS20345	COG3711	transcriptional antiterminator
RK54_RS20350	COG3414	Phosphotransferase system galactitol-specific IIB component
RK54_RS20355	COG3775	system Galactitol-specific IIC component
RK54_RS20390	COG2723	6-phospho-beta-galactosidase activity
RK54_RS20410	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS20410	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK54_RS20415	COG3715	PTS system
RK54_RS20420	COG3716	PTS system mannose fructose sorbose family IID component
RK54_RS20435	COG5464	transposase or invertase
RK54_RS20470	COG1335	isochorismatase
RK54_RS20480	COG3710	Transcriptional regulator
RK54_RS20495	COG2771	luxR family
RK54_RS20515	COG0419	ATPase involved in DNA repair
RK54_RS20530	COG2211	Major facilitator Superfamily
RK54_RS20535	COG1501	Belongs to the glycosyl hydrolase 31 family
RK54_RS20540	COG2982	Protein involved in outer membrane biogenesis
RK54_RS20545	COG2233	PERMEase
RK54_RS20550	COG0786	glutamate:sodium symporter activity
RK54_RS20560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RK54_RS20565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RK54_RS20570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RK54_RS20590	COG2860	membrane
RK54_RS20605	COG0583	DNA-binding transcription factor activity
RK54_RS20610	COG1561	YicC-like family, N-terminal region
RK54_RS20640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RK54_RS20670	COG1519	Transferase
RK54_RS20675	COG0859	PFAM glycosyl transferase family 9
RK54_RS20680	COG0438	transferase activity, transferring glycosyl groups
RK54_RS20760	COG1216	Glycosyl transferase, family 2
RK54_RS20765	COG2861	carbohydrate metabolic process
RK54_RS20770	COG4942	peptidase
RK54_RS20780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RK54_RS20785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RK54_RS20805	COG2271	Major facilitator Superfamily
RK54_RS20820	COG1609	Transcriptional regulator
RK54_RS20825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RK54_RS20835	COG2186	Transcriptional regulator
RK54_RS20870	COG3722	fumarate hydratase activity
RK54_RS20880	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS20880	COG2213	PTS system mannitol-specific
RK54_RS20885	COG0625	glutathione transferase activity
RK54_RS20895	COG3276	selenocysteine insertion sequence binding
RK54_RS20900	COG1940	carbohydrate kinase activity
RK54_RS20905	COG1012	belongs to the aldehyde dehydrogenase family
RK54_RS20920	COG0235	Class ii aldolase
RK54_RS20925	COG3623	hexulose-6-phosphate isomerase
RK54_RS20930	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RK54_RS20935	COG1070	Carbohydrate kinase
RK54_RS20940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RK54_RS20945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RK54_RS20950	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RK54_RS20960	COG2731	YhcH YjgK YiaL family protein
RK54_RS20970	COG1414	Transcriptional regulator
RK54_RS20975	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RK54_RS20980	COG3977	Valine--pyruvate aminotransferase
RK54_RS20985	COG0366	Alpha amylase catalytic
RK54_RS20995	COG2992	FlgJ-related protein
RK54_RS21000	COG2207	Transcriptional regulator
RK54_RS21000	COG1609	Transcriptional regulator
RK54_RS21015	COG1070	Carbohydrate kinase
RK54_RS21020	COG4682	membrane
RK54_RS21025	COG3274	enterobacterial common antigen metabolic process
RK54_RS21050	COG2801	Transposase and inactivated derivatives
RK54_RS21075	COG1278	Cold shock
RK54_RS21080	COG2944	sequence-specific DNA binding
RK54_RS21095	COG2885	chlorophyll binding
RK54_RS21100	COG0243	molybdopterin cofactor binding
RK54_RS21105	COG0456	acetyltransferase
RK54_RS21110	COG2818	Glycosylase
RK54_RS21115	COG5571	outer membrane autotransporter
RK54_RS21160	COG1609	Transcriptional regulator
RK54_RS21175	COG0747	negative chemotaxis
RK54_RS21180	COG0601	transmembrane transport
RK54_RS21185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK54_RS21190	COG0444	Belongs to the ABC transporter superfamily
RK54_RS21195	COG4608	Belongs to the ABC transporter superfamily
RK54_RS21200	COG0814	amino acid
RK54_RS21270	COG2199	diguanylate cyclase activity
RK54_RS21270	COG2200	EAL domain
RK54_RS21285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK54_RS21290	COG2200	EAL domain
RK54_RS21295	COG2982	Protein involved in outer membrane biogenesis
RK54_RS21300	COG0477	Major facilitator Superfamily
RK54_RS21305	COG1295	ribonuclease BN
RK54_RS21310	COG0583	DNA-binding transcription factor activity
RK54_RS21315	COG2197	response regulator
RK54_RS21335	COG2188	Transcriptional regulator
RK54_RS21340	COG2222	sugar isomerase
RK54_RS21345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK54_RS21350	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RK54_RS21360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK54_RS21365	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RK54_RS21370	COG0671	phosphoesterase, PA-phosphatase related
RK54_RS21400	COG0306	phosphate transporter
RK54_RS21405	COG2081	HI0933 family
RK54_RS21410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RK54_RS21415	COG1129	ABC transporter
RK54_RS21415	COG0842	Transport permease protein
RK54_RS21420	COG0842	Transport permease protein
RK54_RS21430	COG2091	lysine biosynthetic process via aminoadipic acid
RK54_RS21435	COG0628	permease
RK54_RS21450	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RK54_RS21470	COG3714	YhhN family
RK54_RS21480	COG3776	membrane
RK54_RS21485	COG0742	ribosomal rna small subunit methyltransferase
RK54_RS21490	COG0552	protein localization to endoplasmic reticulum
RK54_RS21495	COG2884	Cell division ATP-binding protein ftsE
RK54_RS21500	COG2177	Part of the ABC transporter FtsEX involved in
RK54_RS21575	COG0584	glycerophosphoryl diester phosphodiesterase
RK54_RS21585	COG0405	Gamma-glutamyltransferase
RK54_RS21590	COG1735	metal-dependent hydrolase with the TIM-barrel fold
RK54_RS21605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK54_RS21610	COG1247	-acetyltransferase
RK54_RS21615	COG0673	inositol 2-dehydrogenase activity
RK54_RS21620	COG1741	Belongs to the pirin family
RK54_RS21625	COG1609	Transcriptional regulator
RK54_RS21630	COG3265	gluconokinase activity
RK54_RS21635	COG2610	gluconate transmembrane transporter activity
RK54_RS21640	COG2095	MarC family integral membrane protein
RK54_RS21670	COG0058	SHG alpha-glucan phosphorylase activity
RK54_RS21675	COG1414	Transcriptional regulator
RK54_RS21680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RK54_RS21685	COG0129	dihydroxy-acid dehydratase activity
RK54_RS21695	COG0371	Dehydrogenase
RK54_RS21710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RK54_RS21725	COG1349	DNA-binding transcription factor activity
RK54_RS21730	COG4650	regulator
RK54_RS21740	COG1690	Belongs to the RtcB family
RK54_RS21750	COG3077	Addiction module antitoxin, RelB DinJ family
RK54_RS21755	COG3041	Addiction module toxin RelE StbE family
RK54_RS21765	COG0058	SHG alpha-glucan phosphorylase activity
RK54_RS21770	COG1640	4-alpha-glucanotransferase
RK54_RS21775	COG2610	gluconate transmembrane transporter activity
RK54_RS21795	COG5464	transposase or invertase
RK54_RS21810	COG1918	ferrous iron import across plasma membrane
RK54_RS21820	COG2183	response to ionizing radiation
RK54_RS21845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RK54_RS21855	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RK54_RS21860	COG1011	Hydrolase
RK54_RS21870	COG0494	nUDIX hydrolase
RK54_RS21875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RK54_RS21880	COG4972	Pilus assembly protein
RK54_RS21885	COG3166	PFAM Fimbrial assembly family protein
RK54_RS21900	COG4796	Type ii and iii secretion system protein
RK54_RS21920	COG3266	domain, Protein
RK54_RS21925	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RK54_RS21930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RK54_RS21970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RK54_RS22005	COG1289	transmembrane transporter activity
RK54_RS22015	COG1765	OsmC-like protein
RK54_RS22020	COG3954	Phosphoribulokinase
RK54_RS22030	COG0429	hydrolase of the alpha beta-hydrolase fold
RK54_RS22045	COG0488	(ABC) transporter
RK54_RS22060	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
RK54_RS22065	COG1047	Peptidyl-prolyl cis-trans
RK54_RS22080	COG0545	Peptidyl-prolyl cis-trans isomerase
RK54_RS22085	COG2964	Protein conserved in bacteria
RK54_RS22155	COG0051	transcription antitermination factor activity, RNA binding
RK54_RS22180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RK54_RS22260	COG0201	protein transport
RK54_RS22300	COG0789	Transcriptional regulator
RK54_RS22305	COG3036	rescue of stalled ribosome
RK54_RS22335	COG0758	DNA mediated transformation
RK54_RS22345	COG0551	DNA topoisomerase type I activity
RK54_RS22365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RK54_RS22405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK54_RS22410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RK54_RS22415	COG1309	transcriptional regulator
RK54_RS22430	COG2189	Belongs to the N(4) N(6)-methyltransferase family
RK54_RS22450	COG4145	pantothenate transmembrane transporter activity
RK54_RS22455	COG3924	membrane
RK54_RS22460	COG0439	Biotin carboxylase
RK54_RS22465	COG0511	ligase activity, forming carbon-carbon bonds
RK54_RS22480	COG0604	alcohol dehydrogenase
RK54_RS22485	COG2200	EAL domain
RK54_RS22485	COG2199	diguanylate cyclase activity
RK54_RS22500	COG1077	Cell shape determining protein MreB Mrl
RK54_RS22505	COG1792	Involved in formation and maintenance of cell shape
RK54_RS22510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RK54_RS22525	COG3164	Protein of unknown function
RK54_RS22530	COG0312	modulator of DNA gyrase
RK54_RS22535	COG0583	DNA-binding transcription factor activity
RK54_RS22555	COG2732	(Barnase) inhibitor
RK54_RS22580	COG2188	Transcriptional regulator
RK54_RS22590	COG0471	metal ion transport
RK54_RS22595	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RK54_RS22600	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RK54_RS22610	COG0511	ligase activity, forming carbon-carbon bonds
RK54_RS22610	COG5016	pyruvate
RK54_RS22630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK54_RS22635	COG3105	Protein conserved in bacteria
RK54_RS22640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RK54_RS22655	COG0625	glutathione transferase activity
RK54_RS22660	COG2969	positive regulation of protein catabolic process
RK54_RS22690	COG2731	YhcH YjgK YiaL family protein
RK54_RS22695	COG0402	S-adenosylhomocysteine deaminase activity
RK54_RS22700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RK54_RS22705	COG4804	nuclease activity
RK54_RS22710	COG0493	'glutamate synthase
RK54_RS22715	COG0070	glutamate synthase
RK54_RS22715	COG0067	glutamate synthase
RK54_RS22715	COG0069	glutamate synthase activity
RK54_RS22725	COG1242	4 iron, 4 sulfur cluster binding
RK54_RS22730	COG2198	Histidine kinase
RK54_RS22730	COG0784	Response regulator, receiver
RK54_RS22730	COG5002	protein histidine kinase activity
RK54_RS22735	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
RK54_RS22745	COG0515	serine threonine protein kinase
RK54_RS22755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS22780	COG1137	ATPase activity
RK54_RS22785	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RK54_RS22790	COG3117	lipopolysaccharide transmembrane transporter activity
RK54_RS22795	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RK54_RS22805	COG0530	calcium, potassium:sodium antiporter activity
RK54_RS22810	COG1127	ABC transporter
RK54_RS22815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RK54_RS22820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RK54_RS22825	COG2854	intermembrane phospholipid transfer
RK54_RS22830	COG3113	response to antibiotic
RK54_RS22835	COG5007	Belongs to the BolA IbaG family
RK54_RS22845	COG3423	Transcriptional regulator
RK54_RS22850	COG0142	geranyltranstransferase activity
RK54_RS22865	COG0697	spore germination
RK54_RS22875	COG2027	D-alanyl-D-alanine carboxypeptidase
RK54_RS22885	COG1534	Rna-binding protein
RK54_RS22905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RK54_RS22915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RK54_RS22980	COG0513	Belongs to the DEAD box helicase family
RK54_RS22985	COG0814	amino acid
RK54_RS22990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK54_RS22995	COG0826	peptidase U32
RK54_RS23000	COG0826	peptidase U32
RK54_RS23005	COG3154	lipid carrier protein
RK54_RS23010	COG3153	acetyltransferase
RK54_RS23025	COG0693	protein deglycase activity
RK54_RS23030	COG0702	epimerase
RK54_RS23035	COG2823	Periplasmic or secreted lipoprotein
RK54_RS23050	COG3107	peptidoglycan biosynthetic process
RK54_RS23055	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RK54_RS23065	COG1063	alcohol dehydrogenase
RK54_RS23070	COG3775	system Galactitol-specific IIC component
RK54_RS23075	COG3414	Phosphotransferase system galactitol-specific IIB component
RK54_RS23080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK54_RS23095	COG2721	sulfolactate sulfo-lyase activity
RK54_RS23105	COG2084	Dehydrogenase
RK54_RS23110	COG1929	Belongs to the glycerate kinase type-1 family
RK54_RS23130	COG0583	DNA-binding transcription factor activity
RK54_RS23150	COG1882	Formate acetyltransferase
RK54_RS23155	COG1760	l-serine dehydratase
RK54_RS23160	COG0814	amino acid
RK54_RS23175	COG1741	Belongs to the pirin family
RK54_RS23180	COG0583	DNA-binding transcription factor activity
RK54_RS23185	COG3152	Membrane
RK54_RS23190	COG0435	Glutathione S-transferase
RK54_RS23195	COG2259	Doxx family
RK54_RS23205	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
RK54_RS23210	COG4575	ribosome binding
RK54_RS23215	COG1422	Protein of unknown function (DUF1090)
RK54_RS23225	COG0586	Pfam SNARE associated Golgi protein
RK54_RS23245	COG0673	inositol 2-dehydrogenase activity
RK54_RS23250	COG2949	membrane
RK54_RS23255	COG1451	nucleotide metabolic process
RK54_RS23265	COG1902	pentaerythritol trinitrate reductase activity
RK54_RS23265	COG0446	pyridine nucleotide-disulphide oxidoreductase
RK54_RS23280	COG0840	transmembrane signaling receptor activity
RK54_RS23285	COG0840	transmembrane signaling receptor activity
RK54_RS23290	COG1695	Transcriptional regulator
RK54_RS23295	COG2375	cellular response to nickel ion
RK54_RS23320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RK54_RS23335	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RK54_RS23345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RK54_RS23360	COG4991	sh3 domain protein
RK54_RS23370	COG3025	triphosphatase activity
RK54_RS23390	COG2268	Band 7 protein
RK54_RS23395	COG1585	Membrane protein implicated in regulation of membrane protease activity
RK54_RS23440	COG3384	dioxygenase
RK54_RS23445	COG0754	glutathionylspermidine amidase activity
RK54_RS23465	COG0494	nUDIX hydrolase
RK54_RS23470	COG3151	Protein conserved in bacteria
RK54_RS23475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RK54_RS23480	COG3150	esterase
RK54_RS23490	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RK54_RS23495	COG2249	NAD(P)H dehydrogenase (quinone) activity
RK54_RS23510	COG3111	PFAM Bacterial OB fold (BOF) protein
RK54_RS23515	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RK54_RS23565	COG0471	metal ion transport
RK54_RS23575	COG1979	alcohol dehydrogenase
RK54_RS23580	COG2207	Transcriptional regulator
RK54_RS23605	COG0848	biopolymer transport protein
RK54_RS23610	COG1028	Short-chain dehydrogenase reductase Sdr
RK54_RS23635	COG0840	transmembrane signaling receptor activity
RK54_RS23650	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RK54_RS23655	COG0437	4 iron, 4 sulfur cluster binding
RK54_RS23660	COG5557	Pfam Polysulphide reductase, NrfD
RK54_RS23665	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
RK54_RS23670	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RK54_RS23675	COG1773	rubredoxin
RK54_RS23685	COG0298	carbon dioxide binding
RK54_RS23690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK54_RS23700	COG0625	glutathione transferase activity
RK54_RS23705	COG0754	glutathionylspermidine amidase activity
RK54_RS23725	COG0246	Mannitol dehydrogenase
RK54_RS23735	COG2271	Major facilitator Superfamily
RK54_RS23760	COG1012	belongs to the aldehyde dehydrogenase family
RK54_RS23765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RK54_RS23775	COG0531	amino acid
RK54_RS23805	COG2301	Belongs to the HpcH HpaI aldolase family
RK54_RS23810	COG2030	dehydratase
RK54_RS23815	COG0427	acetyl-CoA hydrolase
RK54_RS23830	COG1811	Na channel or pump
RK54_RS23840	COG1982	Orn Lys Arg decarboxylase major
RK54_RS23845	COG2211	Major facilitator Superfamily
RK54_RS23875	COG3171	Protein conserved in bacteria
RK54_RS23885	COG0252	asparaginase activity
RK54_RS23895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RK54_RS23910	COG0762	integral membrane protein
RK54_RS23915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RK54_RS23920	COG2805	Type II/IV secretion system protein
RK54_RS23945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RK54_RS23950	COG2356	endonuclease I
RK54_RS23960	COG2814	Major facilitator Superfamily
RK54_RS23985	COG1166	arginine decarboxylase activity
RK54_RS23995	COG2186	Transcriptional regulator
RK54_RS24005	COG0246	Mannitol dehydrogenase
RK54_RS24010	COG1063	alcohol dehydrogenase
RK54_RS24015	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RK54_RS24020	COG2731	YhcH YjgK YiaL family protein
RK54_RS24025	COG2267	carboxylic ester hydrolase activity
RK54_RS24035	COG0501	Belongs to the peptidase M48B family
RK54_RS24040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RK54_RS24045	COG1122	ATPase activity
RK54_RS24050	COG1122	ATPase activity
RK54_RS24085	COG0191	fructose-bisphosphate aldolase activity
RK54_RS24090	COG0668	transmembrane transport
RK54_RS24100	COG2968	Membrane
RK54_RS24120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK54_RS24125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RK54_RS24150	COG0006	proline dipeptidase activity
RK54_RS24155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RK54_RS24160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RK54_RS24190	COG2723	6-phospho-beta-galactosidase activity
RK54_RS24200	COG1272	protein, Hemolysin III