locus-tag	class	description
E5N88_RS00005	COG0460	homoserine dehydrogenase
E5N88_RS00005	COG0527	aspartate kinase activity
E5N88_RS00015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E5N88_RS00025	COG1115	amino acid carrier protein
E5N88_RS00035	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5N88_RS00040	COG1584	GPR1 FUN34 yaaH family protein
E5N88_RS00045	COG4735	regulation of single-species biofilm formation
E5N88_RS00110	COG3188	usher protein
E5N88_RS00125	COG3539	Fimbrial protein
E5N88_RS00130	COG3121	Chaperone
E5N88_RS00150	COG0583	DNA-binding transcription factor activity
E5N88_RS00165	COG0737	Belongs to the 5'-nucleotidase family
E5N88_RS00175	COG3119	arylsulfatase activity
E5N88_RS00180	COG0641	radical SAM
E5N88_RS00200	COG0583	DNA-binding transcription factor activity
E5N88_RS00225	COG0196	riboflavin kinase activity
E5N88_RS00240	COG1047	Peptidyl-prolyl cis-trans
E5N88_RS00400	COG2271	Major facilitator Superfamily
E5N88_RS00420	COG3119	arylsulfatase activity
E5N88_RS00485	COG0417	DNA replication proofreading
E5N88_RS00525	COG0586	Pfam SNARE associated Golgi protein
E5N88_RS00615	COG0768	penicillin binding
E5N88_RS00625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E5N88_RS00640	COG0772	Belongs to the SEDS family
E5N88_RS00665	COG0849	cell division
E5N88_RS00670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E5N88_RS00690	COG0494	nUDIX hydrolase
E5N88_RS00725	COG1459	type II secretion system
E5N88_RS00730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E5N88_RS00735	COG4969	Belongs to the N-Me-Phe pilin family
E5N88_RS00755	COG3725	Membrane protein required for beta-lactamase induction
E5N88_RS00760	COG3940	Belongs to the glycosyl hydrolase 43 family
E5N88_RS00765	COG2211	Major facilitator Superfamily
E5N88_RS00780	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E5N88_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
E5N88_RS00790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5N88_RS00805	COG3064	Membrane
E5N88_RS00840	COG1349	DNA-binding transcription factor activity
E5N88_RS00865	COG4993	Dehydrogenase
E5N88_RS00875	COG0288	reversible hydration of carbon dioxide
E5N88_RS00880	COG1131	(ABC) transporter
E5N88_RS00885	COG0842	Transport permease protein
E5N88_RS00890	COG3539	Fimbrial protein
E5N88_RS00910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS00915	COG0726	polysaccharide deacetylase
E5N88_RS00935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5N88_RS00960	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E5N88_RS00965	COG1643	Atp-dependent helicase
E5N88_RS00970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E5N88_RS00975	COG4774	siderophore transport
E5N88_RS00980	COG1120	ATPase activity
E5N88_RS00985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E5N88_RS01005	COG3188	usher protein
E5N88_RS01010	COG3121	Chaperone
E5N88_RS01015	COG3539	Fimbrial protein
E5N88_RS01020	COG3539	Fimbrial protein
E5N88_RS01050	COG2860	membrane
E5N88_RS01075	COG3835	regulator
E5N88_RS01085	COG0477	Major facilitator Superfamily
E5N88_RS01135	COG0575	Belongs to the CDS family
E5N88_RS01200	COG0346	lactoylglutathione lyase activity
E5N88_RS01210	COG4568	rho-dependent transcription termination
E5N88_RS01225	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E5N88_RS01230	COG3015	lipoprotein NlpE involved in copper resistance
E5N88_RS01240	COG1720	tRNA m6t6A37 methyltransferase activity
E5N88_RS01305	COG0583	DNA-binding transcription factor activity
E5N88_RS01310	COG2814	Major facilitator Superfamily
E5N88_RS01320	COG2226	methyltransferase
E5N88_RS01325	COG0741	lytic transglycosylase activity
E5N88_RS01325	COG1388	LysM domain
E5N88_RS01335	COG2226	methyltransferase
E5N88_RS01440	COG2885	chlorophyll binding
E5N88_RS01440	COG3047	cAMP biosynthetic process
E5N88_RS01475	COG3501	Rhs element vgr protein
E5N88_RS01485	COG3209	COG3209 Rhs family protein
E5N88_RS01495	COG3209	COG3209 Rhs family protein
E5N88_RS01515	COG3209	COG3209 Rhs family protein
E5N88_RS01585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5N88_RS01600	COG0121	glutamine amidotransferase
E5N88_RS01605	COG3034	peptidoglycan biosynthetic process
E5N88_RS01620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E5N88_RS01625	COG2195	Cleaves the N-terminal amino acid of tripeptides
E5N88_RS01665	COG0582	viral genome integration into host DNA
E5N88_RS01725	COG4712	double-strand break repair protein
E5N88_RS01790	COG0305	Participates in initiation and elongation during chromosome replication
E5N88_RS01845	COG0484	heat shock protein binding
E5N88_RS01865	COG3772	lysozyme
E5N88_RS01995	COG0463	Glycosyl transferase, family 2
E5N88_RS02000	COG2246	polysaccharide biosynthetic process
E5N88_RS02025	COG2814	Major facilitator Superfamily
E5N88_RS02040	COG0179	Fumarylacetoacetate (FAA) hydrolase
E5N88_RS02075	COG3188	usher protein
E5N88_RS02080	COG3121	Chaperone
E5N88_RS02085	COG3539	Fimbrial protein
E5N88_RS02100	COG2200	EAL domain
E5N88_RS02145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N88_RS02155	COG0789	Transcriptional regulator
E5N88_RS02165	COG2814	Major facilitator Superfamily
E5N88_RS02185	COG1271	oxidase subunit
E5N88_RS02190	COG1294	oxidase, subunit
E5N88_RS02210	COG1280	lysine exporter protein (LysE YggA)
E5N88_RS02245	COG0113	porphobilinogen synthase activity
E5N88_RS02260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E5N88_RS02270	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E5N88_RS02315	COG3706	GGDEF domain
E5N88_RS02320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E5N88_RS02340	COG4126	flavin adenine dinucleotide binding
E5N88_RS02355	COG1940	carbohydrate kinase activity
E5N88_RS02360	COG2814	Major facilitator Superfamily
E5N88_RS02365	COG0419	ATPase involved in DNA repair
E5N88_RS02370	COG0420	3'-5' exonuclease activity
E5N88_RS02380	COG5002	protein histidine kinase activity
E5N88_RS02395	COG0366	Alpha amylase catalytic
E5N88_RS02400	COG0450	alkyl hydroperoxide reductase
E5N88_RS02420	COG1862	Preprotein translocase
E5N88_RS02430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E5N88_RS02470	COG4238	major outer membrane lipoprotein
E5N88_RS02480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5N88_RS02480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5N88_RS02500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E5N88_RS02505	COG0667	Aldo Keto reductase
E5N88_RS02515	COG0142	geranyltranstransferase activity
E5N88_RS02550	COG2188	Transcriptional regulator
E5N88_RS02580	COG2814	Major facilitator Superfamily
E5N88_RS02605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E5N88_RS02610	COG1845	cytochrome c oxidase, subunit III
E5N88_RS02615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E5N88_RS02620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E5N88_RS02625	COG2223	nitrite transmembrane transporter activity
E5N88_RS02630	COG3056	Lipoprotein
E5N88_RS02635	COG0271	Belongs to the BolA IbaG family
E5N88_RS02660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E5N88_RS02670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E5N88_RS02675	COG1555	photosystem II stabilization
E5N88_RS02680	COG0824	Thioesterase
E5N88_RS02690	COG4533	DNA binding
E5N88_RS02710	COG1522	sequence-specific DNA binding
E5N88_RS02715	COG1132	(ABC) transporter
E5N88_RS02720	COG1132	(ABC) transporter
E5N88_RS02730	COG0347	Belongs to the P(II) protein family
E5N88_RS02735	COG0004	ammonium transporteR
E5N88_RS02740	COG1946	Acyl-CoA thioesterase
E5N88_RS02745	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E5N88_RS02750	COG3695	enzyme binding
E5N88_RS02760	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5N88_RS02780	COG0110	maltose O-acetyltransferase activity
E5N88_RS02795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5N88_RS02800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N88_RS02805	COG1309	transcriptional regulator
E5N88_RS02810	COG1196	nuclear chromosome segregation
E5N88_RS02810	COG3264	Mechanosensitive ion channel
E5N88_RS02815	COG5464	transposase or invertase
E5N88_RS02825	COG3923	Primosomal replication protein n
E5N88_RS02830	COG2832	Protein of unknown function (DUF454)
E5N88_RS02875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS02880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E5N88_RS02880	COG4651	solute:proton antiporter activity
E5N88_RS02885	COG2223	nitrite transmembrane transporter activity
E5N88_RS02900	COG3735	TraB family
E5N88_RS02920	COG1585	Membrane protein implicated in regulation of membrane protease activity
E5N88_RS02925	COG0330	HflC and HflK could
E5N88_RS02930	COG4619	ABC transporter
E5N88_RS02935	COG0390	transport system, permease component
E5N88_RS02940	COG3118	belongs to the thioredoxin family
E5N88_RS02945	COG0300	oxidoreductase activity
E5N88_RS02950	COG2755	lipolytic protein G-D-S-L family
E5N88_RS02955	COG4181	ATPase activity
E5N88_RS02960	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E5N88_RS02970	COG1464	Belongs to the NlpA lipoprotein family
E5N88_RS03005	COG3960	tartronate-semialdehyde synthase activity
E5N88_RS03010	COG3622	Belongs to the hyi family
E5N88_RS03015	COG2084	Dehydrogenase
E5N88_RS03025	COG1953	Uracil, thiamine, allantoin
E5N88_RS03035	COG2233	PERMEase
E5N88_RS03040	COG1929	Belongs to the glycerate kinase type-1 family
E5N88_RS03045	COG3257	ureidoglycine aminohydrolase activity
E5N88_RS03050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E5N88_RS03055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E5N88_RS03060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5N88_RS03065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5N88_RS03075	COG0549	Belongs to the carbamate kinase family
E5N88_RS03080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E5N88_RS03085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E5N88_RS03095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E5N88_RS03115	COG1988	membrane-bound metal-dependent
E5N88_RS03120	COG2501	S4 domain
E5N88_RS03190	COG0582	viral genome integration into host DNA
E5N88_RS03205	COG0463	Glycosyl transferase, family 2
E5N88_RS03210	COG2246	polysaccharide biosynthetic process
E5N88_RS03220	COG5002	protein histidine kinase activity
E5N88_RS03225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5N88_RS03230	COG2207	Transcriptional regulator
E5N88_RS03235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5N88_RS03245	COG3059	membrane
E5N88_RS03255	COG1113	amino acid transport
E5N88_RS03260	COG0668	transmembrane transport
E5N88_RS03270	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E5N88_RS03270	COG3933	PFAM sigma-54 factor interaction domain-containing protein
E5N88_RS03275	COG2222	sugar isomerase
E5N88_RS03285	COG3716	PTS system mannose fructose sorbose family IID component
E5N88_RS03310	COG2315	Protein conserved in bacteria
E5N88_RS03340	COG4771	TonB-dependent receptor
E5N88_RS03345	COG2382	esterase
E5N88_RS03350	COG3251	PFAM MbtH domain protein
E5N88_RS03355	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E5N88_RS03355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E5N88_RS03360	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E5N88_RS03365	COG1120	ATPase activity
E5N88_RS03370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5N88_RS03375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5N88_RS03385	COG4592	Periplasmic binding protein
E5N88_RS03390	COG1169	isochorismate synthase
E5N88_RS03395	COG1021	2,3-dihydroxybenzoate-AMP ligase
E5N88_RS03400	COG3433	isochorismatase activity
E5N88_RS03400	COG1535	isochorismatase
E5N88_RS03405	COG1028	Short-chain dehydrogenase reductase Sdr
E5N88_RS03415	COG1966	Carbon starvation protein
E5N88_RS03420	COG2879	small protein
E5N88_RS03425	COG0371	Dehydrogenase
E5N88_RS03430	COG0436	Aminotransferase
E5N88_RS03435	COG1475	DNA binding
E5N88_RS03440	COG3969	phosphoadenosine phosphosulfate
E5N88_RS03445	COG0583	DNA-binding transcription factor activity
E5N88_RS03450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5N88_RS03470	COG0243	molybdopterin cofactor binding
E5N88_RS03490	COG1063	alcohol dehydrogenase
E5N88_RS03495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E5N88_RS03500	COG3719	Belongs to the RNase T2 family
E5N88_RS03505	COG0471	metal ion transport
E5N88_RS03520	COG3051	citrate lyase alpha subunit
E5N88_RS03525	COG2301	Belongs to the HpcH HpaI aldolase family
E5N88_RS03535	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E5N88_RS03540	COG3290	protein histidine kinase activity
E5N88_RS03545	COG4565	transcriptional regulatory protein
E5N88_RS03550	COG3069	C4-dicarboxylate transmembrane transporter activity
E5N88_RS03570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5N88_RS03585	COG0583	DNA-binding transcription factor activity
E5N88_RS03600	COG1686	Belongs to the peptidase S11 family
E5N88_RS03610	COG0772	Belongs to the SEDS family
E5N88_RS03615	COG0768	penicillin binding
E5N88_RS03625	COG0799	negative regulation of ribosome biogenesis
E5N88_RS03645	COG1466	dna polymerase III delta subunit
E5N88_RS03675	COG3290	protein histidine kinase activity
E5N88_RS03675	COG3829	transcription factor binding
E5N88_RS03680	COG2888	peptidyl-tyrosine sulfation
E5N88_RS03695	COG2214	Heat shock protein DnaJ domain protein
E5N88_RS03705	COG2214	Heat shock protein DnaJ domain protein
E5N88_RS03710	COG0443	Heat shock 70 kDa protein
E5N88_RS03725	COG1126	abc transporter atp-binding protein
E5N88_RS03730	COG0765	amino acid transport
E5N88_RS03735	COG0765	amino acid transport
E5N88_RS03760	COG1702	phosphate starvation-inducible protein PhoH
E5N88_RS03770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5N88_RS03815	COG0367	asparagine synthase
E5N88_RS03820	COG0647	UMP catabolic process
E5N88_RS03825	COG1940	carbohydrate kinase activity
E5N88_RS03825	COG1846	Transcriptional regulator
E5N88_RS03830	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5N88_RS03870	COG1053	succinate dehydrogenase
E5N88_RS03875	COG0583	DNA-binding transcription factor activity
E5N88_RS03880	COG0735	belongs to the Fur family
E5N88_RS03895	COG0596	Alpha beta hydrolase
E5N88_RS03905	COG0033	Phosphoglucomutase
E5N88_RS03915	COG0531	amino acid
E5N88_RS03920	COG1982	Orn Lys Arg decarboxylase major
E5N88_RS03930	COG0745	RESPONSE REGULATOR receiver
E5N88_RS03935	COG2205	protein histidine kinase activity
E5N88_RS03980	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E5N88_RS03985	COG1984	allophanate hydrolase subunit 2
E5N88_RS04000	COG0582	viral genome integration into host DNA
E5N88_RS04040	COG1216	Glycosyl transferase, family 2
E5N88_RS04065	COG3180	Ammonia monooxygenase
E5N88_RS04080	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E5N88_RS04095	COG0567	Dehydrogenase, E1 component
E5N88_RS04100	COG0508	dehydrogenase complex catalyzes the overall conversion of
E5N88_RS04110	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5N88_RS04115	COG1271	oxidase subunit
E5N88_RS04120	COG1294	oxidase, subunit
E5N88_RS04125	COG4890	Cyd operon protein YbgT
E5N88_RS04130	COG3790	cyd operon protein YbgE
E5N88_RS04135	COG0824	Thioesterase
E5N88_RS04140	COG0811	peptide transport
E5N88_RS04145	COG0848	biopolymer transport protein
E5N88_RS04150	COG3064	Membrane
E5N88_RS04160	COG2885	chlorophyll binding
E5N88_RS04165	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E5N88_RS04225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E5N88_RS04230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N88_RS04230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N88_RS04235	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N88_RS04240	COG0583	DNA-binding transcription factor activity
E5N88_RS04245	COG0583	DNA-binding transcription factor activity
E5N88_RS04250	COG0490	domain, Protein
E5N88_RS04250	COG0471	metal ion transport
E5N88_RS04275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5N88_RS04280	COG1120	ATPase activity
E5N88_RS04290	COG2017	converts alpha-aldose to the beta-anomer
E5N88_RS04315	COG1119	ATPase activity
E5N88_RS04320	COG3585	molybdate ion transport
E5N88_RS04320	COG2005	Transcriptional regulator
E5N88_RS04330	COG0725	ABC transporter, periplasmic molybdate-binding protein
E5N88_RS04335	COG4149	molybdate abc transporter
E5N88_RS04345	COG0561	phosphatase activity
E5N88_RS04355	COG4677	pectinesterase activity
E5N88_RS04385	COG1881	PFAM PEBP family protein
E5N88_RS04445	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5N88_RS04455	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E5N88_RS04465	COG0670	Belongs to the BI1 family
E5N88_RS04495	COG0392	lysyltransferase activity
E5N88_RS04505	COG3568	Endonuclease Exonuclease Phosphatase
E5N88_RS04515	COG0842	Transport permease protein
E5N88_RS04520	COG0842	Transport permease protein
E5N88_RS04525	COG1131	(ABC) transporter
E5N88_RS04535	COG1309	transcriptional regulator
E5N88_RS04540	COG0513	Belongs to the DEAD box helicase family
E5N88_RS04550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E5N88_RS04560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E5N88_RS04570	COG0668	transmembrane transport
E5N88_RS04575	COG1126	abc transporter atp-binding protein
E5N88_RS04580	COG0765	amino acid transport
E5N88_RS04585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N88_RS04600	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E5N88_RS04605	COG2194	sulfuric ester hydrolase activity
E5N88_RS04620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E5N88_RS04625	COG1376	ErfK ybiS ycfS ynhG family protein
E5N88_RS04630	COG0488	(ABC) transporter
E5N88_RS04650	COG0561	phosphatase activity
E5N88_RS04655	COG1882	Formate acetyltransferase
E5N88_RS04660	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5N88_RS04710	COG2301	Belongs to the HpcH HpaI aldolase family
E5N88_RS04730	COG1960	acyl-CoA dehydrogenase activity
E5N88_RS04745	COG0583	DNA-binding transcription factor activity
E5N88_RS04750	COG2610	gluconate transmembrane transporter activity
E5N88_RS04755	COG2133	pyrroloquinoline quinone binding
E5N88_RS04760	COG0625	glutathione transferase activity
E5N88_RS04765	COG1686	Belongs to the peptidase S11 family
E5N88_RS04770	COG1349	DNA-binding transcription factor activity
E5N88_RS04775	COG0671	phosphoesterase, PA-phosphatase related
E5N88_RS04780	COG2814	Major facilitator Superfamily
E5N88_RS04785	COG0561	phosphatase activity
E5N88_RS04790	COG0738	Major facilitator superfamily
E5N88_RS04795	COG3226	Transcriptional regulator
E5N88_RS04840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E5N88_RS04845	COG3842	ATPase activity
E5N88_RS04850	COG1176	ABC-type spermidine putrescine transport system, permease component I
E5N88_RS04855	COG1177	transmembrane transport
E5N88_RS04885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N88_RS04890	COG4160	amino acid transport
E5N88_RS04895	COG4215	(ABC) transporter
E5N88_RS04900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N88_RS04905	COG1126	abc transporter atp-binding protein
E5N88_RS04920	COG3023	N-Acetylmuramoyl-L-alanine amidase
E5N88_RS04925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5N88_RS04930	COG0702	epimerase
E5N88_RS04935	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E5N88_RS04940	COG0028	Belongs to the TPP enzyme family
E5N88_RS04945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5N88_RS04955	COG2431	L-lysine efflux transmembrane transporter activity
E5N88_RS04960	COG3593	DNA synthesis involved in DNA repair
E5N88_RS04965	COG2990	Protein conserved in bacteria
E5N88_RS04970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N88_RS04980	COG1278	Cold shock
E5N88_RS04990	COG0542	response to heat
E5N88_RS05015	COG1335	isochorismatase
E5N88_RS05025	COG0583	DNA-binding transcription factor activity
E5N88_RS05045	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E5N88_RS05050	COG4988	ABC transporter
E5N88_RS05055	COG0492	ferredoxin-NADP+ reductase activity
E5N88_RS05075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E5N88_RS05085	COG0243	molybdopterin cofactor binding
E5N88_RS05090	COG0437	4 iron, 4 sulfur cluster binding
E5N88_RS05095	COG3302	dmso reductase anchor subunit
E5N88_RS05105	COG0531	amino acid
E5N88_RS05110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5N88_RS05125	COG1882	Formate acetyltransferase
E5N88_RS05130	COG2116	formate transmembrane transporter activity
E5N88_RS05135	COG1944	ATP diphosphatase activity
E5N88_RS05140	COG2323	membrane
E5N88_RS05155	COG0501	Belongs to the peptidase M48B family
E5N88_RS05165	COG0539	negative regulation of cytoplasmic translation
E5N88_RS05175	COG0658	competence protein
E5N88_RS05175	COG2333	competence protein COMEC
E5N88_RS05190	COG3214	Protein conserved in bacteria
E5N88_RS05210	COG3173	Aminoglycoside phosphotransferase
E5N88_RS05215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E5N88_RS05220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E5N88_RS05230	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E5N88_RS05240	COG2989	Protein conserved in bacteria
E5N88_RS05245	COG3108	Peptidase M15
E5N88_RS05250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E5N88_RS05270	COG1522	sequence-specific DNA binding
E5N88_RS05285	COG1115	amino acid carrier protein
E5N88_RS05295	COG0582	viral genome integration into host DNA
E5N88_RS05315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N88_RS05350	COG1484	DNA-dependent DNA replication
E5N88_RS05460	COG4220	transposase activity
E5N88_RS05515	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N88_RS05540	COG2135	peptidase activity
E5N88_RS05560	COG0308	aminopeptidase N
E5N88_RS05575	COG3217	Mosc domain protein beta barrel domain protein
E5N88_RS05575	COG0633	Ferredoxin
E5N88_RS05585	COG0488	(ABC) transporter
E5N88_RS05590	COG2995	paraquat-inducible protein a
E5N88_RS05595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E5N88_RS05595	COG3008	intermembrane lipid transfer
E5N88_RS05600	COG3009	Protein conserved in bacteria
E5N88_RS05605	COG3130	regulation of translation
E5N88_RS05615	COG1067	ATP-dependent peptidase activity
E5N88_RS05635	COG3070	regulator of competence-specific genes
E5N88_RS05640	COG1289	transmembrane transporter activity
E5N88_RS05645	COG3304	Inner membrane component domain
E5N88_RS05650	COG0210	DNA helicase
E5N88_RS05665	COG1832	CoA-binding protein
E5N88_RS05680	COG1881	PFAM PEBP family protein
E5N88_RS05700	COG0670	Belongs to the BI1 family
E5N88_RS05750	COG2205	protein histidine kinase activity
E5N88_RS05755	COG0745	RESPONSE REGULATOR receiver
E5N88_RS05770	COG2368	4-hydroxyphenylacetate
E5N88_RS05775	COG1846	Transcriptional regulator
E5N88_RS05785	COG1012	belongs to the aldehyde dehydrogenase family
E5N88_RS05790	COG3384	dioxygenase
E5N88_RS05800	COG3971	2-oxopent-4-enoate hydratase activity
E5N88_RS05850	COG4232	protein-disulfide reductase activity
E5N88_RS05855	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E5N88_RS05855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5N88_RS05860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E5N88_RS05880	COG3729	General stress protein
E5N88_RS05885	COG1309	transcriptional regulator
E5N88_RS05905	COG1702	phosphate starvation-inducible protein PhoH
E5N88_RS05910	COG1737	Transcriptional regulator
E5N88_RS05915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E5N88_RS05935	COG2814	Major facilitator Superfamily
E5N88_RS05940	COG0673	inositol 2-dehydrogenase activity
E5N88_RS05975	COG3381	protein complex oligomerization
E5N88_RS06030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5N88_RS06055	COG5645	(Lipo)protein
E5N88_RS06070	COG1560	Kdo2-lipid A biosynthetic process
E5N88_RS06085	COG3038	cytochrome b561
E5N88_RS06120	COG2999	glutathione oxidoreductase activity
E5N88_RS06130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5N88_RS06220	COG1530	ribonuclease E activity
E5N88_RS06285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5N88_RS06290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E5N88_RS06295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E5N88_RS06305	COG0470	DNA polymerase III
E5N88_RS06310	COG0084	hydrolase, TatD family'
E5N88_RS06320	COG4773	Receptor
E5N88_RS06325	COG0537	adenosine 5'-monophosphoramidase activity
E5N88_RS06330	COG5633	Lipoprotein
E5N88_RS06355	COG1252	NADH dehydrogenase
E5N88_RS06360	COG3134	Outer membrane lipoprotein
E5N88_RS06365	COG1309	transcriptional regulator
E5N88_RS06375	COG1376	ErfK ybiS ycfS ynhG family protein
E5N88_RS06375	COG1388	LysM domain
E5N88_RS06380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E5N88_RS06385	COG4591	ABC-type transport system involved in lipoprotein release permease component
E5N88_RS06390	COG1136	(ABC) transporter
E5N88_RS06395	COG4591	ABC-type transport system involved in lipoprotein release permease component
E5N88_RS06415	COG1177	transmembrane transport
E5N88_RS06445	COG2850	peptidyl-arginine hydroxylation
E5N88_RS06460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E5N88_RS06490	COG0538	isocitrate dehydrogenase activity
E5N88_RS06560	COG0071	Belongs to the small heat shock protein (HSP20) family
E5N88_RS06570	COG3038	cytochrome b561
E5N88_RS06600	COG1124	(ABC) transporter
E5N88_RS06605	COG0668	transmembrane transport
E5N88_RS06620	COG3443	Belongs to the bacterial solute-binding protein 9 family
E5N88_RS06635	COG0789	Transcriptional regulator
E5N88_RS06650	COG1605	Chorismate mutase
E5N88_RS06660	COG3615	Tellurite resistance protein tehB
E5N88_RS06680	COG2261	transglycosylase associated protein
E5N88_RS06690	COG3042	response to heat
E5N88_RS06700	COG3189	MarR family transcriptional regulator
E5N88_RS06705	COG2807	transmembrane transport
E5N88_RS06710	COG2207	Transcriptional regulator
E5N88_RS06725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E5N88_RS06730	COG2199	diguanylate cyclase activity
E5N88_RS06745	COG2766	serine protein kinase
E5N88_RS06750	COG3713	MltA-interacting MipA family protein
E5N88_RS06755	COG0641	radical SAM
E5N88_RS06760	COG0656	L-ascorbic acid biosynthetic process
E5N88_RS06780	COG3139	Protein of unknown function (DUF1315)
E5N88_RS06785	COG1335	isochorismatase
E5N88_RS06790	COG0252	asparaginase activity
E5N88_RS06795	COG0616	signal peptide processing
E5N88_RS06800	COG0778	Nitroreductase
E5N88_RS06825	COG0494	nUDIX hydrolase
E5N88_RS06860	COG3678	ATP-independent chaperone mediated protein folding
E5N88_RS06875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5N88_RS06885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E5N88_RS06890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E5N88_RS06895	COG1447	Phosphotransferase system cellobiose-specific component IIA
E5N88_RS06900	COG1917	Cupin 2, conserved barrel domain protein
E5N88_RS06900	COG2169	Transcriptional regulator
E5N88_RS06905	COG1486	melibiose metabolic process
E5N88_RS06915	COG0753	catalase activity
E5N88_RS06930	COG1988	membrane-bound metal-dependent
E5N88_RS06935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5N88_RS06945	COG3001	Fructosamine kinase
E5N88_RS06955	COG1105	Belongs to the carbohydrate kinase PfkB family
E5N88_RS06960	COG3137	Salt-induced outer membrane protein
E5N88_RS07040	COG0386	Belongs to the glutathione peroxidase family
E5N88_RS07050	COG0791	NLP P60 protein
E5N88_RS07065	COG4256	Hemin uptake protein
E5N88_RS07080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5N88_RS07080	COG0574	Belongs to the PEP-utilizing enzyme family
E5N88_RS07085	COG0318	PFAM AMP-dependent synthetase and ligase
E5N88_RS07090	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E5N88_RS07095	COG0644	oxidoreductase
E5N88_RS07100	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E5N88_RS07105	COG2086	electron transfer activity
E5N88_RS07110	COG2207	Transcriptional regulator
E5N88_RS07110	COG1917	Cupin 2, conserved barrel domain protein
E5N88_RS07115	COG1960	acyl-CoA dehydrogenase activity
E5N88_RS07120	COG4670	ketone body catabolic process
E5N88_RS07135	COG2271	Major facilitator Superfamily
E5N88_RS07140	COG0738	Major facilitator superfamily
E5N88_RS07155	COG0628	permease
E5N88_RS07160	COG0277	FAD linked oxidase domain protein
E5N88_RS07160	COG0247	lactate metabolic process
E5N88_RS07165	COG2050	protein possibly involved in aromatic compounds catabolism
E5N88_RS07180	COG0316	Belongs to the HesB IscA family
E5N88_RS07185	COG0719	Fe-S assembly protein
E5N88_RS07190	COG0396	ATPase activity
E5N88_RS07195	COG0719	Fe-S assembly protein
E5N88_RS07210	COG1376	ErfK ybiS ycfS ynhG family protein
E5N88_RS07230	COG0531	amino acid
E5N88_RS07235	COG2267	carboxylic ester hydrolase activity
E5N88_RS07245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS07280	COG3272	Protein of unknown function (DUF1722)
E5N88_RS07285	COG0789	Transcriptional regulator
E5N88_RS07465	COG0307	riboflavin synthase, alpha
E5N88_RS07470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E5N88_RS07475	COG2814	Major facilitator Superfamily
E5N88_RS07480	COG0583	DNA-binding transcription factor activity
E5N88_RS07500	COG0791	NLP P60 protein
E5N88_RS07505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E5N88_RS07525	COG1902	pentaerythritol trinitrate reductase activity
E5N88_RS07530	COG1309	transcriptional regulator
E5N88_RS07535	COG3313	Fe-S protein
E5N88_RS07540	COG4989	oxidoreductase activity
E5N88_RS07555	COG1566	PFAM secretion protein HlyD family protein
E5N88_RS07580	COG3895	Periplasmic Protein
E5N88_RS07600	COG0625	glutathione transferase activity
E5N88_RS07610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E5N88_RS07660	COG0673	inositol 2-dehydrogenase activity
E5N88_RS07675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N88_RS07675	COG1263	PTS System
E5N88_RS07680	COG5339	Protein conserved in bacteria
E5N88_RS07705	COG2205	protein histidine kinase activity
E5N88_RS07710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
E5N88_RS07715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E5N88_RS07725	COG0745	RESPONSE REGULATOR receiver
E5N88_RS07730	COG3136	membrane protein required for alginate biosynthesis
E5N88_RS07735	COG0531	amino acid
E5N88_RS07745	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E5N88_RS07750	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E5N88_RS07755	COG0628	permease
E5N88_RS07775	COG3591	Belongs to the peptidase S1B family
E5N88_RS07785	COG2814	Major facilitator Superfamily
E5N88_RS07790	COG0583	DNA-binding transcription factor activity
E5N88_RS07795	COG1940	carbohydrate kinase activity
E5N88_RS07835	COG3302	dmso reductase anchor subunit
E5N88_RS07840	COG0437	4 iron, 4 sulfur cluster binding
E5N88_RS07845	COG0243	molybdopterin cofactor binding
E5N88_RS07850	COG0243	molybdopterin cofactor binding
E5N88_RS07865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5N88_RS07885	COG1063	alcohol dehydrogenase
E5N88_RS07890	COG0477	Major facilitator Superfamily
E5N88_RS07895	COG0477	Major facilitator Superfamily
E5N88_RS07900	COG0246	Mannitol dehydrogenase
E5N88_RS07910	COG1802	Transcriptional regulator
E5N88_RS07915	COG4221	oxidoreductase activity
E5N88_RS07930	COG3729	General stress protein
E5N88_RS07935	COG1546	Belongs to the CinA family
E5N88_RS07940	COG3111	PFAM Bacterial OB fold (BOF) protein
E5N88_RS07950	COG2814	Major facilitator Superfamily
E5N88_RS07990	COG0583	DNA-binding transcription factor activity
E5N88_RS07995	COG1012	belongs to the aldehyde dehydrogenase family
E5N88_RS08010	COG3781	membrane
E5N88_RS08035	COG1773	rubredoxin
E5N88_RS08060	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E5N88_RS08065	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5N88_RS08075	COG2186	Transcriptional regulator
E5N88_RS08080	COG1063	alcohol dehydrogenase
E5N88_RS08085	COG2271	Major facilitator Superfamily
E5N88_RS08110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E5N88_RS08115	COG0251	oxidation-reduction process
E5N88_RS08165	COG1609	Transcriptional regulator
E5N88_RS08170	COG1757	Na H antiporter
E5N88_RS08175	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E5N88_RS08190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E5N88_RS08205	COG1764	response to oxidative stress
E5N88_RS08225	COG1064	alcohol dehydrogenase
E5N88_RS08230	COG2864	formate dehydrogenase
E5N88_RS08235	COG0437	4 iron, 4 sulfur cluster binding
E5N88_RS08275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E5N88_RS08280	COG1140	nitrate reductase beta subunit
E5N88_RS08285	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E5N88_RS08290	COG2181	nitrate reductase activity
E5N88_RS08330	COG4772	TonB-dependent receptor
E5N88_RS08335	COG1802	Transcriptional regulator
E5N88_RS08340	COG2130	NADP-dependent
E5N88_RS08350	COG3238	Protein conserved in bacteria
E5N88_RS08390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5N88_RS08395	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E5N88_RS08420	COG0826	peptidase U32
E5N88_RS08425	COG1396	sequence-specific DNA binding
E5N88_RS08430	COG3135	benzoate transporter
E5N88_RS08440	COG0500	methyltransferase
E5N88_RS08445	COG1275	C4-dicarboxylate transporter malic acid transport protein
E5N88_RS08450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E5N88_RS08455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5N88_RS08465	COG3414	Phosphotransferase system galactitol-specific IIB component
E5N88_RS08470	COG3775	system Galactitol-specific IIC component
E5N88_RS08475	COG0434	BtpA family
E5N88_RS08480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS08485	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E5N88_RS08490	COG1349	DNA-binding transcription factor activity
E5N88_RS08500	COG1304	FMN binding
E5N88_RS08505	COG2353	YceI-like domain
E5N88_RS08515	COG2272	Belongs to the type-B carboxylesterase lipase family
E5N88_RS08520	COG5383	Protein conserved in bacteria
E5N88_RS08525	COG0583	DNA-binding transcription factor activity
E5N88_RS08530	COG0840	transmembrane signaling receptor activity
E5N88_RS08565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N88_RS08570	COG0765	amino acid transport
E5N88_RS08580	COG0765	amino acid transport
E5N88_RS08590	COG0500	methyltransferase
E5N88_RS08595	COG3038	cytochrome b561
E5N88_RS08600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E5N88_RS08605	COG1643	Atp-dependent helicase
E5N88_RS08620	COG3784	Protein of unknown function (DUF1318)
E5N88_RS08630	COG2911	Protein conserved in bacteria
E5N88_RS08635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E5N88_RS08640	COG3187	Heat shock protein
E5N88_RS08645	COG3042	response to heat
E5N88_RS08655	COG0674	pyruvate-flavodoxin oxidoreductase activity
E5N88_RS08655	COG1013	pyruvate-flavodoxin oxidoreductase activity
E5N88_RS08655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5N88_RS08655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E5N88_RS08665	COG2076	Multidrug Resistance protein
E5N88_RS08685	COG0513	Belongs to the DEAD box helicase family
E5N88_RS08700	COG0840	transmembrane signaling receptor activity
E5N88_RS08705	COG2840	Smr protein MutS2
E5N88_RS08725	COG3182	Iron-regulated membrane protein
E5N88_RS08730	COG0668	transmembrane transport
E5N88_RS08750	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E5N88_RS08785	COG1309	transcriptional regulator
E5N88_RS08790	COG1028	Short-chain dehydrogenase reductase Sdr
E5N88_RS08795	COG0656	L-ascorbic acid biosynthetic process
E5N88_RS08800	COG0583	DNA-binding transcription factor activity
E5N88_RS08810	COG4166	transmembrane transport
E5N88_RS08815	COG2866	Carboxypeptidase
E5N88_RS08820	COG4948	Mandelate Racemase Muconate Lactonizing
E5N88_RS08840	COG3106	COG3106 Predicted ATPase
E5N88_RS08845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5N88_RS08855	COG1983	PspC domain protein
E5N88_RS08865	COG1842	Phage shock protein A
E5N88_RS08870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E5N88_RS08925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5N88_RS08925	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5N88_RS08935	COG5001	Diguanylate cyclase
E5N88_RS08945	COG1349	DNA-binding transcription factor activity
E5N88_RS08965	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E5N88_RS08970	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E5N88_RS08975	COG0671	phosphoesterase, PA-phosphatase related
E5N88_RS09015	COG0616	signal peptide processing
E5N88_RS09020	COG1028	Short-chain dehydrogenase reductase Sdr
E5N88_RS09035	COG0009	L-threonylcarbamoyladenylate synthase
E5N88_RS09075	COG3729	General stress protein
E5N88_RS09080	COG3685	Protein conserved in bacteria
E5N88_RS09085	COG3685	Protein conserved in bacteria
E5N88_RS09090	COG3546	catalase activity
E5N88_RS09100	COG0727	PFAM Uncharacterised protein family (UPF0153)
E5N88_RS09125	COG2350	Protein conserved in bacteria
E5N88_RS09145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E5N88_RS09175	COG2095	MarC family integral membrane protein
E5N88_RS09180	COG1454	alcohol dehydrogenase
E5N88_RS09180	COG1012	belongs to the aldehyde dehydrogenase family
E5N88_RS09195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E5N88_RS09200	COG0745	RESPONSE REGULATOR receiver
E5N88_RS09205	COG1752	Esterase of the alpha-beta hydrolase superfamily
E5N88_RS09215	COG0788	formyltetrahydrofolate deformylase activity
E5N88_RS09250	COG2181	nitrate reductase activity
E5N88_RS09255	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E5N88_RS09260	COG1140	nitrate reductase beta subunit
E5N88_RS09265	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E5N88_RS09270	COG2223	nitrite transmembrane transporter activity
E5N88_RS09275	COG3850	Histidine kinase
E5N88_RS09280	COG2197	response regulator
E5N88_RS09285	COG4932	domain protein
E5N88_RS09290	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E5N88_RS09295	COG4572	Cation transport regulator
E5N88_RS09300	COG0387	Pfam Sodium calcium exchanger
E5N88_RS09350	COG0659	secondary active sulfate transmembrane transporter activity
E5N88_RS09365	COG0012	GTP binding
E5N88_RS09375	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5N88_RS09385	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E5N88_RS09390	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5N88_RS09395	COG1999	signal sequence binding
E5N88_RS09400	COG1773	rubredoxin
E5N88_RS09405	COG1271	oxidase subunit
E5N88_RS09410	COG1294	oxidase, subunit
E5N88_RS09420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E5N88_RS09445	COG1619	proteins homologs of microcin C7 resistance protein MccF
E5N88_RS09465	COG2719	SpoVR family
E5N88_RS09505	COG0179	Fumarylacetoacetate (FAA) hydrolase
E5N88_RS09520	COG2894	cell division
E5N88_RS09530	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E5N88_RS09540	COG3065	identical protein binding
E5N88_RS09550	COG1199	ATP-dependent helicase activity
E5N88_RS09555	COG0251	oxidation-reduction process
E5N88_RS09575	COG1760	l-serine dehydratase
E5N88_RS09580	COG2200	EAL domain
E5N88_RS09585	COG1253	flavin adenine dinucleotide binding
E5N88_RS09590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N88_RS09590	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS09595	COG3715	PTS system
E5N88_RS09600	COG3716	PTS system mannose fructose sorbose family IID component
E5N88_RS09615	COG2226	methyltransferase
E5N88_RS09620	COG0768	penicillin binding
E5N88_RS09650	COG1414	Transcriptional regulator
E5N88_RS09655	COG2814	Major facilitator Superfamily
E5N88_RS09675	COG1956	GAF domain-containing protein
E5N88_RS09680	COG2995	paraquat-inducible protein a
E5N88_RS09685	COG3008	intermembrane lipid transfer
E5N88_RS09720	COG5562	phage envelope protein
E5N88_RS09730	COG0454	-acetyltransferase
E5N88_RS09835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N88_RS09850	COG1276	copper resistance
E5N88_RS09855	COG2372	response to copper ion
E5N88_RS09865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5N88_RS09870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N88_RS09875	COG1770	oligopeptidase
E5N88_RS09880	COG2979	Protein of unknown function (DUF533)
E5N88_RS09890	COG3141	response to X-ray
E5N88_RS09900	COG0800	Aldolase
E5N88_RS09905	COG0129	dihydroxy-acid dehydratase activity
E5N88_RS09910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E5N88_RS09915	COG1737	Transcriptional regulator
E5N88_RS09925	COG1560	Kdo2-lipid A biosynthetic process
E5N88_RS09930	COG0739	heme binding
E5N88_RS09935	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E5N88_RS09945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5N88_RS09980	COG0494	nUDIX hydrolase
E5N88_RS09990	COG1335	isochorismatase
E5N88_RS09995	COG1801	Protein of unknown function DUF72
E5N88_RS10000	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E5N88_RS10020	COG3102	Protein conserved in bacteria
E5N88_RS10035	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E5N88_RS10140	COG1528	Iron-storage protein
E5N88_RS10155	COG1528	Iron-storage protein
E5N88_RS10165	COG0814	amino acid
E5N88_RS10170	COG3012	SEC-C Motif Domain Protein
E5N88_RS10170	COG3318	Belongs to the UPF0149 family
E5N88_RS10215	COG2197	response regulator
E5N88_RS10230	COG2197	response regulator
E5N88_RS10310	COG0425	Belongs to the sulfur carrier protein TusA family
E5N88_RS10415	COG5475	Uncharacterized small protein (DUF2158)
E5N88_RS10420	COG2354	Protein conserved in bacteria
E5N88_RS10425	COG0697	spore germination
E5N88_RS10430	COG3727	T/G mismatch-specific endonuclease activity
E5N88_RS10435	COG0270	DNA (cytosine-5-)-methyltransferase activity
E5N88_RS10440	COG1418	mRNA catabolic process
E5N88_RS10450	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E5N88_RS10525	COG3778	Protein conserved in bacteria
E5N88_RS10530	COG3299	homolog of phage Mu protein gp47
E5N88_RS10575	COG4386	tail sheath protein
E5N88_RS10620	COG4695	Portal protein
E5N88_RS10630	COG4626	Terminase
E5N88_RS10630	COG1802	Transcriptional regulator
E5N88_RS10660	COG3179	chitinase
E5N88_RS10685	COG0484	heat shock protein binding
E5N88_RS10690	COG1403	HNH endonuclease
E5N88_RS10700	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E5N88_RS10705	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E5N88_RS10725	COG3646	Phage regulatory protein
E5N88_RS10765	COG5532	Uncharacterized conserved protein (DUF2303)
E5N88_RS10770	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E5N88_RS10820	COG0582	viral genome integration into host DNA
E5N88_RS10875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E5N88_RS10900	COG0534	Mate efflux family protein
E5N88_RS11065	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E5N88_RS11095	COG1012	belongs to the aldehyde dehydrogenase family
E5N88_RS11095	COG1454	alcohol dehydrogenase
E5N88_RS11100	COG4656	Part of a membrane complex involved in electron transport
E5N88_RS11135	COG1289	transmembrane transporter activity
E5N88_RS11175	COG2925	Exonuclease
E5N88_RS11180	COG0531	amino acid
E5N88_RS11190	COG0583	DNA-binding transcription factor activity
E5N88_RS11195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5N88_RS11355	COG2327	Polysaccharide pyruvyl transferase
E5N88_RS11360	COG2244	polysaccharide biosynthetic process
E5N88_RS11365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E5N88_RS11380	COG0297	glycogen (starch) synthase activity
E5N88_RS11390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5N88_RS11395	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E5N88_RS11400	COG0110	maltose O-acetyltransferase activity
E5N88_RS11405	COG1216	Glycosyl transferase, family 2
E5N88_RS11415	COG0438	transferase activity, transferring glycosyl groups
E5N88_RS11420	COG1045	serine acetyltransferase
E5N88_RS11425	COG0463	Glycosyl transferase, family 2
E5N88_RS11445	COG1253	flavin adenine dinucleotide binding
E5N88_RS11450	COG2982	Protein involved in outer membrane biogenesis
E5N88_RS11465	COG3447	MASE1 domain protein
E5N88_RS11465	COG5001	Diguanylate cyclase
E5N88_RS11465	COG5002	protein histidine kinase activity
E5N88_RS11470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E5N88_RS11475	COG0443	Heat shock 70 kDa protein
E5N88_RS11505	COG2205	protein histidine kinase activity
E5N88_RS11510	COG0745	RESPONSE REGULATOR receiver
E5N88_RS11555	COG1830	Aldolase
E5N88_RS11560	COG2211	Major facilitator Superfamily
E5N88_RS11565	COG1397	ADP-ribosylglycohydrolase
E5N88_RS11570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS11575	COG2188	Transcriptional regulator
E5N88_RS11590	COG5455	response to cobalt ion
E5N88_RS11595	COG3539	Fimbrial protein
E5N88_RS11600	COG3188	usher protein
E5N88_RS11605	COG3121	Chaperone
E5N88_RS11630	COG4808	Protein conserved in bacteria
E5N88_RS11640	COG4807	Protein conserved in bacteria
E5N88_RS11650	COG3275	phosphorelay sensor kinase activity
E5N88_RS11665	COG1174	glycine betaine transport
E5N88_RS11670	COG1125	glycine betaine transport
E5N88_RS11675	COG1174	glycine betaine transport
E5N88_RS11680	COG1732	Glycine betaine
E5N88_RS11690	COG0277	FAD linked oxidase domain protein
E5N88_RS11695	COG1686	Belongs to the peptidase S11 family
E5N88_RS11705	COG0586	Pfam SNARE associated Golgi protein
E5N88_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
E5N88_RS11715	COG1538	Outer membrane efflux protein
E5N88_RS11730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5N88_RS11735	COG0625	glutathione transferase activity
E5N88_RS11750	COG2271	Major facilitator Superfamily
E5N88_RS11765	COG1346	cytolysis
E5N88_RS11775	COG2949	membrane
E5N88_RS11815	COG2311	Membrane
E5N88_RS11835	COG1760	l-serine dehydratase
E5N88_RS11840	COG0560	Phosphoserine phosphatase
E5N88_RS11845	COG2271	Major facilitator Superfamily
E5N88_RS11850	COG4771	TonB-dependent receptor
E5N88_RS11855	COG0833	amino acid
E5N88_RS11860	COG0583	DNA-binding transcription factor activity
E5N88_RS11865	COG2855	membrane
E5N88_RS11875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N88_RS11875	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E5N88_RS11875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N88_RS11880	COG1105	Belongs to the carbohydrate kinase PfkB family
E5N88_RS11915	COG0523	cobalamin synthesis protein
E5N88_RS11920	COG0671	phosphoesterase, PA-phosphatase related
E5N88_RS11925	COG0791	NLP P60 protein
E5N88_RS11930	COG2200	EAL domain
E5N88_RS11935	COG4166	transmembrane transport
E5N88_RS11940	COG4174	ABC transporter (Permease)
E5N88_RS11945	COG4239	(ABC) transporter, permease
E5N88_RS11950	COG4172	Belongs to the ABC transporter superfamily
E5N88_RS11960	COG2814	Major facilitator Superfamily
E5N88_RS11970	COG1061	Type III restriction enzyme res subunit
E5N88_RS12065	COG1403	HNH endonuclease
E5N88_RS12085	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N88_RS12100	COG2197	response regulator
E5N88_RS12105	COG3088	subunit of a heme lyase
E5N88_RS12105	COG4235	cytochrome complex assembly
E5N88_RS12125	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N88_RS12130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N88_RS12135	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N88_RS12140	COG4133	protoheme IX ABC transporter activity
E5N88_RS12145	COG3005	denitrification pathway
E5N88_RS12150	COG3043	anaerobic respiration
E5N88_RS12155	COG0348	domain, Protein
E5N88_RS12160	COG0437	4 iron, 4 sulfur cluster binding
E5N88_RS12170	COG3062	negative regulation of establishment of protein localization
E5N88_RS12175	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N88_RS12175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N88_RS12185	COG4615	Cyclic peptide transporter
E5N88_RS12210	COG0642	Histidine kinase
E5N88_RS12210	COG2198	Histidine kinase
E5N88_RS12230	COG4948	Mandelate Racemase Muconate Lactonizing
E5N88_RS12260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5N88_RS12265	COG2814	Major facilitator Superfamily
E5N88_RS12270	COG0583	DNA-binding transcription factor activity
E5N88_RS12275	COG0584	glycerophosphoryl diester phosphodiesterase
E5N88_RS12280	COG2271	Major facilitator Superfamily
E5N88_RS12285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E5N88_RS12295	COG0247	lactate metabolic process
E5N88_RS12315	COG2271	Major facilitator Superfamily
E5N88_RS12325	COG1414	Transcriptional regulator
E5N88_RS12415	COG1169	isochorismate synthase
E5N88_RS12420	COG4575	ribosome binding
E5N88_RS12425	COG2153	protein acetylation
E5N88_RS12435	COG0784	Response regulator, receiver
E5N88_RS12435	COG0835	chemotaxis
E5N88_RS12440	COG2304	oxidoreductase activity
E5N88_RS12455	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5N88_RS12460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E5N88_RS12470	COG0839	Belongs to the complex I subunit 6 family
E5N88_RS12520	COG0583	DNA-binding transcription factor activity
E5N88_RS12525	COG0436	Aminotransferase
E5N88_RS12540	COG0490	domain, Protein
E5N88_RS12540	COG0471	metal ion transport
E5N88_RS12545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5N88_RS12570	COG1288	antiporter activity
E5N88_RS12575	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E5N88_RS12580	COG3959	Transketolase, thiamine diphosphate binding domain
E5N88_RS12585	COG3037	sugar-specific permease SgaT UlaA
E5N88_RS12595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS12600	COG1609	Transcriptional regulator
E5N88_RS12610	COG0622	Phosphoesterase
E5N88_RS12615	COG0625	glutathione transferase activity
E5N88_RS12620	COG0625	glutathione transferase activity
E5N88_RS12625	COG1090	epimerase
E5N88_RS12660	COG0833	amino acid
E5N88_RS12665	COG3457	Alanine racemase
E5N88_RS12670	COG0531	amino acid
E5N88_RS12680	COG3829	transcription factor binding
E5N88_RS12685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E5N88_RS12690	COG1286	toxin biosynthetic process
E5N88_RS12695	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E5N88_RS12700	COG0285	dihydrofolate synthase activity
E5N88_RS12710	COG0586	Pfam SNARE associated Golgi protein
E5N88_RS12720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E5N88_RS12745	COG3423	Transcriptional regulator
E5N88_RS12770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5N88_RS12785	COG3101	peptidyl-lysine hydroxylation
E5N88_RS12790	COG0730	response to heat
E5N88_RS12815	COG2062	phosphohistidine phosphatase, SixA
E5N88_RS12830	COG3691	Protein conserved in bacteria
E5N88_RS12845	COG2116	formate transmembrane transporter activity
E5N88_RS12885	COG1560	Kdo2-lipid A biosynthetic process
E5N88_RS12895	COG0436	Aminotransferase
E5N88_RS12910	COG3961	Belongs to the TPP enzyme family
E5N88_RS12915	COG0667	Aldo Keto reductase
E5N88_RS12930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E5N88_RS12935	COG2200	EAL domain
E5N88_RS12935	COG2199	diguanylate cyclase activity
E5N88_RS12950	COG3415	Transposase
E5N88_RS12955	COG3415	Transposase
E5N88_RS12985	COG0583	DNA-binding transcription factor activity
E5N88_RS12995	COG2211	Major facilitator Superfamily
E5N88_RS13000	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E5N88_RS13010	COG0583	DNA-binding transcription factor activity
E5N88_RS13015	COG0385	Bile acid
E5N88_RS13020	COG3530	Putative quorum-sensing-regulated virulence factor
E5N88_RS13045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS13100	COG4208	sulfate ABC transporter
E5N88_RS13125	COG2837	iron assimilation
E5N88_RS13260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E5N88_RS13270	COG5342	invasion associated locus B
E5N88_RS13285	COG0493	'glutamate synthase
E5N88_RS13285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N88_RS13290	COG3850	Histidine kinase
E5N88_RS13295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5N88_RS13305	COG1393	Belongs to the ArsC family
E5N88_RS13325	COG2321	neutral zinc metallopeptidase
E5N88_RS13335	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E5N88_RS13345	COG2716	regulation of RNA biosynthetic process
E5N88_RS13350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5N88_RS13355	COG1929	Belongs to the glycerate kinase type-1 family
E5N88_RS13360	COG0628	permease
E5N88_RS13370	COG1393	Belongs to the ArsC family
E5N88_RS13380	COG2233	PERMEase
E5N88_RS13395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E5N88_RS13410	COG2200	EAL domain
E5N88_RS13450	COG0517	IMP dehydrogenase activity
E5N88_RS13450	COG0516	GMP reductase activity
E5N88_RS13490	COG1645	bacterial-type flagellum-dependent swarming motility
E5N88_RS13505	COG2976	Protein conserved in bacteria
E5N88_RS13545	COG0437	4 iron, 4 sulfur cluster binding
E5N88_RS13550	COG0243	molybdopterin cofactor binding
E5N88_RS13555	COG4953	penicillin-binding protein 1C
E5N88_RS13560	COG2373	Large extracellular alpha-helical protein
E5N88_RS13565	COG2897	thiosulfate sulfurtransferase activity
E5N88_RS13585	COG2975	iron-sulfur cluster assembly
E5N88_RS13590	COG0633	Ferredoxin
E5N88_RS13610	COG0822	iron-sulfur transferase activity
E5N88_RS13655	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E5N88_RS13665	COG3711	transcriptional antiterminator
E5N88_RS13670	COG2814	Major facilitator Superfamily
E5N88_RS13680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5N88_RS13680	COG1017	nitric oxide dioxygenase activity
E5N88_RS13685	COG3710	Transcriptional regulator
E5N88_RS13690	COG0531	amino acid
E5N88_RS13700	COG3104	oligopeptide transport
E5N88_RS13705	COG0347	Belongs to the P(II) protein family
E5N88_RS13710	COG2204	response regulator
E5N88_RS13715	COG3170	Tfp pilus assembly protein FimV
E5N88_RS13720	COG2205	protein histidine kinase activity
E5N88_RS13745	COG0560	Phosphoserine phosphatase
E5N88_RS13750	COG1263	PTS System
E5N88_RS13750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N88_RS13760	COG1737	Transcriptional regulator
E5N88_RS13765	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E5N88_RS13770	COG2223	nitrite transmembrane transporter activity
E5N88_RS13775	COG0583	DNA-binding transcription factor activity
E5N88_RS13780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N88_RS13850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E5N88_RS13870	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N88_RS13980	COG4220	transposase activity
E5N88_RS14090	COG1484	DNA-dependent DNA replication
E5N88_RS14125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N88_RS14150	COG3086	response to oxidative stress
E5N88_RS14190	COG0513	Belongs to the DEAD box helicase family
E5N88_RS14195	COG0583	DNA-binding transcription factor activity
E5N88_RS14215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5N88_RS14220	COG3118	belongs to the thioredoxin family
E5N88_RS14235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5N88_RS14240	COG5544	Lipoprotein
E5N88_RS14245	COG0477	Major facilitator Superfamily
E5N88_RS14275	COG0542	response to heat
E5N88_RS14290	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5N88_RS14295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E5N88_RS14305	COG1196	nuclear chromosome segregation
E5N88_RS14335	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N88_RS14430	COG4695	Portal protein
E5N88_RS14470	COG4974	Belongs to the 'phage' integrase family
E5N88_RS14480	COG0077	Prephenate dehydratase
E5N88_RS14480	COG1605	Chorismate mutase
E5N88_RS14490	COG1605	Chorismate mutase
E5N88_RS14490	COG0287	Prephenate dehydrogenase
E5N88_RS14505	COG2199	diguanylate cyclase activity
E5N88_RS14530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E5N88_RS14535	COG4137	Cytochrome C assembly protein
E5N88_RS14540	COG4536	flavin adenine dinucleotide binding
E5N88_RS14560	COG0497	DNA recombination
E5N88_RS14575	COG2867	negative regulation of translational initiation
E5N88_RS14600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N88_RS14610	COG0582	viral genome integration into host DNA
E5N88_RS14615	COG0582	viral genome integration into host DNA
E5N88_RS14645	COG4133	protoheme IX ABC transporter activity
E5N88_RS14660	COG3423	Transcriptional regulator
E5N88_RS14680	COG0673	inositol 2-dehydrogenase activity
E5N88_RS14715	COG2819	hydrolase of the alpha beta superfamily
E5N88_RS14735	COG2990	Protein conserved in bacteria
E5N88_RS14750	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E5N88_RS14755	COG0642	Histidine kinase
E5N88_RS14785	COG0579	oxidoreductase
E5N88_RS14790	COG1012	belongs to the aldehyde dehydrogenase family
E5N88_RS14795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E5N88_RS14800	COG1113	amino acid transport
E5N88_RS14805	COG1802	Transcriptional regulator
E5N88_RS14810	COG1652	LysM domain
E5N88_RS14820	COG0401	homolog of Blt101
E5N88_RS14825	COG0640	Transcriptional regulator
E5N88_RS14830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5N88_RS14860	COG4575	ribosome binding
E5N88_RS14870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5N88_RS14915	COG2814	Major facilitator Superfamily
E5N88_RS14920	COG1846	Transcriptional regulator
E5N88_RS14925	COG1566	PFAM secretion protein HlyD family protein
E5N88_RS14930	COG2814	Major facilitator Superfamily
E5N88_RS14950	COG1238	metal cluster binding
E5N88_RS14955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5N88_RS14985	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E5N88_RS15010	COG1546	Belongs to the CinA family
E5N88_RS15020	COG2951	lytic endotransglycosylase activity
E5N88_RS15025	COG3730	PTS system glucitol sorbitol-specific
E5N88_RS15030	COG3732	PTS system glucitol sorbitol-specific
E5N88_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
E5N88_RS15045	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS15050	COG1349	DNA-binding transcription factor activity
E5N88_RS15075	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E5N88_RS15080	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N88_RS15090	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5N88_RS15100	COG3260	NADH ubiquinone oxidoreductase 20
E5N88_RS15105	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5N88_RS15110	COG3261	NADH dehydrogenase
E5N88_RS15110	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E5N88_RS15115	COG0650	Formate hydrogenlyase subunit 4
E5N88_RS15120	COG0651	ATP synthesis coupled electron transport
E5N88_RS15125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N88_RS15140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E5N88_RS15145	COG0298	carbon dioxide binding
E5N88_RS15150	COG0409	Hydrogenase expression formation protein
E5N88_RS15155	COG0309	Hydrogenase expression formation protein (HypE)
E5N88_RS15175	COG1121	(ABC) transporter
E5N88_RS15180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5N88_RS15185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5N88_RS15360	COG2207	Transcriptional regulator
E5N88_RS15425	COG0477	Major facilitator Superfamily
E5N88_RS15435	COG2610	gluconate transmembrane transporter activity
E5N88_RS15440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5N88_RS15445	COG3622	Belongs to the hyi family
E5N88_RS15450	COG0235	Class ii aldolase
E5N88_RS15460	COG2084	Dehydrogenase
E5N88_RS15465	COG1349	DNA-binding transcription factor activity
E5N88_RS15475	COG0163	prenyltransferase activity
E5N88_RS15480	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E5N88_RS15550	COG2234	aminopeptidase activity
E5N88_RS15555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N88_RS15560	COG1518	maintenance of DNA repeat elements
E5N88_RS15575	COG1857	crispr-associated protein
E5N88_RS15615	COG0720	synthase
E5N88_RS15620	COG0321	lipoyl(octanoyl) transferase activity
E5N88_RS15620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E5N88_RS15625	COG0602	queuosine metabolic process
E5N88_RS15640	COG3956	TIGRFAM MazG family protein
E5N88_RS15655	COG3609	addiction module antidote protein, CC2985 family
E5N88_RS15660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5N88_RS15670	COG4999	Histidine kinase
E5N88_RS15670	COG3850	Histidine kinase
E5N88_RS15670	COG3437	response regulator, receiver
E5N88_RS15670	COG2205	protein histidine kinase activity
E5N88_RS15675	COG1929	Belongs to the glycerate kinase type-1 family
E5N88_RS15680	COG4948	Mandelate Racemase Muconate Lactonizing
E5N88_RS15685	COG4948	Mandelate Racemase Muconate Lactonizing
E5N88_RS15690	COG2271	Major facilitator Superfamily
E5N88_RS15700	COG0716	FMN binding
E5N88_RS15710	COG3098	single-species biofilm formation
E5N88_RS15730	COG1611	Belongs to the LOG family
E5N88_RS15735	COG0814	amino acid
E5N88_RS15740	COG1760	l-serine dehydratase
E5N88_RS15750	COG1454	alcohol dehydrogenase
E5N88_RS15755	COG0235	Class ii aldolase
E5N88_RS15760	COG0738	Major facilitator superfamily
E5N88_RS15780	COG1349	DNA-binding transcription factor activity
E5N88_RS15790	COG2363	Small membrane protein
E5N88_RS15795	COG0583	DNA-binding transcription factor activity
E5N88_RS15805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E5N88_RS15810	COG2166	iron-sulfur cluster assembly
E5N88_RS15815	COG2962	Rard protein
E5N88_RS15820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E5N88_RS15825	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E5N88_RS15835	COG0860	N-Acetylmuramoyl-L-alanine amidase
E5N88_RS15845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E5N88_RS15850	COG1074	ATP-dependent DNA helicase activity
E5N88_RS15860	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E5N88_RS15865	COG4967	type IV pilus modification protein PilV
E5N88_RS15875	COG4795	General secretion pathway protein
E5N88_RS15880	COG2165	general secretion pathway protein
E5N88_RS15910	COG0861	Integral membrane protein TerC family
E5N88_RS15920	COG0667	Aldo Keto reductase
E5N88_RS15940	COG1609	Transcriptional regulator
E5N88_RS15950	COG0583	DNA-binding transcription factor activity
E5N88_RS15955	COG1794	racemase activity, acting on amino acids and derivatives
E5N88_RS15960	COG2814	Major facilitator Superfamily
E5N88_RS15965	COG1028	Short-chain dehydrogenase reductase Sdr
E5N88_RS15975	COG0183	Belongs to the thiolase family
E5N88_RS15990	COG0814	amino acid
E5N88_RS16025	COG3188	usher protein
E5N88_RS16075	COG4942	peptidase
E5N88_RS16130	COG1272	protein, Hemolysin III
E5N88_RS16140	COG2723	6-phospho-beta-galactosidase activity
E5N88_RS16170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5N88_RS16175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5N88_RS16180	COG0006	proline dipeptidase activity
E5N88_RS16200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E5N88_RS16205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E5N88_RS16220	COG2968	Membrane
E5N88_RS16230	COG0668	transmembrane transport
E5N88_RS16235	COG0191	fructose-bisphosphate aldolase activity
E5N88_RS16265	COG1122	ATPase activity
E5N88_RS16270	COG1122	ATPase activity
E5N88_RS16275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E5N88_RS16280	COG0501	Belongs to the peptidase M48B family
E5N88_RS16290	COG2267	carboxylic ester hydrolase activity
E5N88_RS16295	COG2731	YhcH YjgK YiaL family protein
E5N88_RS16300	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E5N88_RS16305	COG1063	alcohol dehydrogenase
E5N88_RS16310	COG0246	Mannitol dehydrogenase
E5N88_RS16320	COG2186	Transcriptional regulator
E5N88_RS16330	COG1166	arginine decarboxylase activity
E5N88_RS16350	COG2814	Major facilitator Superfamily
E5N88_RS16360	COG2356	endonuclease I
E5N88_RS16365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E5N88_RS16390	COG2805	Type II/IV secretion system protein
E5N88_RS16395	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E5N88_RS16400	COG0762	integral membrane protein
E5N88_RS16415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E5N88_RS16425	COG0252	asparaginase activity
E5N88_RS16435	COG3171	Protein conserved in bacteria
E5N88_RS16460	COG2211	Major facilitator Superfamily
E5N88_RS16465	COG1982	Orn Lys Arg decarboxylase major
E5N88_RS16470	COG1811	Na channel or pump
E5N88_RS16485	COG0427	acetyl-CoA hydrolase
E5N88_RS16490	COG2030	dehydratase
E5N88_RS16495	COG2301	Belongs to the HpcH HpaI aldolase family
E5N88_RS16525	COG0531	amino acid
E5N88_RS16535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E5N88_RS16540	COG1012	belongs to the aldehyde dehydrogenase family
E5N88_RS16565	COG2271	Major facilitator Superfamily
E5N88_RS16575	COG0246	Mannitol dehydrogenase
E5N88_RS16590	COG0754	glutathionylspermidine amidase activity
E5N88_RS16595	COG0625	glutathione transferase activity
E5N88_RS16610	COG0298	carbon dioxide binding
E5N88_RS16620	COG1773	rubredoxin
E5N88_RS16625	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5N88_RS16630	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E5N88_RS16635	COG5557	Pfam Polysulphide reductase, NrfD
E5N88_RS16640	COG0437	4 iron, 4 sulfur cluster binding
E5N88_RS16645	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5N88_RS16655	COG0840	transmembrane signaling receptor activity
E5N88_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
E5N88_RS16685	COG0848	biopolymer transport protein
E5N88_RS16705	COG2207	Transcriptional regulator
E5N88_RS16710	COG1979	alcohol dehydrogenase
E5N88_RS16720	COG0471	metal ion transport
E5N88_RS16775	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5N88_RS16780	COG3111	PFAM Bacterial OB fold (BOF) protein
E5N88_RS16795	COG2249	NAD(P)H dehydrogenase (quinone) activity
E5N88_RS16800	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E5N88_RS16810	COG3150	esterase
E5N88_RS16815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E5N88_RS16820	COG3151	Protein conserved in bacteria
E5N88_RS16825	COG0494	nUDIX hydrolase
E5N88_RS16840	COG0754	glutathionylspermidine amidase activity
E5N88_RS16845	COG3384	dioxygenase
E5N88_RS16885	COG1585	Membrane protein implicated in regulation of membrane protease activity
E5N88_RS16890	COG2268	Band 7 protein
E5N88_RS16910	COG3025	triphosphatase activity
E5N88_RS16915	COG4991	sh3 domain protein
E5N88_RS16930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E5N88_RS16950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E5N88_RS17005	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N88_RS17100	COG4695	Portal protein
E5N88_RS17165	COG4974	Belongs to the 'phage' integrase family
E5N88_RS17175	COG2375	cellular response to nickel ion
E5N88_RS17180	COG1695	Transcriptional regulator
E5N88_RS17185	COG0840	transmembrane signaling receptor activity
E5N88_RS17190	COG0840	transmembrane signaling receptor activity
E5N88_RS17200	COG1902	pentaerythritol trinitrate reductase activity
E5N88_RS17200	COG0446	pyridine nucleotide-disulphide oxidoreductase
E5N88_RS17210	COG1451	nucleotide metabolic process
E5N88_RS17215	COG2949	membrane
E5N88_RS17220	COG0673	inositol 2-dehydrogenase activity
E5N88_RS17235	COG0586	Pfam SNARE associated Golgi protein
E5N88_RS17245	COG1422	Protein of unknown function (DUF1090)
E5N88_RS17250	COG4575	ribosome binding
E5N88_RS17255	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E5N88_RS17265	COG2259	Doxx family
E5N88_RS17270	COG0435	Glutathione S-transferase
E5N88_RS17275	COG3152	Membrane
E5N88_RS17280	COG0583	DNA-binding transcription factor activity
E5N88_RS17285	COG1741	Belongs to the pirin family
E5N88_RS17300	COG0814	amino acid
E5N88_RS17305	COG1760	l-serine dehydratase
E5N88_RS17310	COG1882	Formate acetyltransferase
E5N88_RS17330	COG0583	DNA-binding transcription factor activity
E5N88_RS17340	COG1929	Belongs to the glycerate kinase type-1 family
E5N88_RS17345	COG2084	Dehydrogenase
E5N88_RS17355	COG2721	sulfolactate sulfo-lyase activity
E5N88_RS17360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS17365	COG1349	DNA-binding transcription factor activity
E5N88_RS17375	COG1105	Belongs to the carbohydrate kinase PfkB family
E5N88_RS17380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS17380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N88_RS17380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N88_RS17395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS17400	COG3414	Phosphotransferase system galactitol-specific IIB component
E5N88_RS17405	COG3775	system Galactitol-specific IIC component
E5N88_RS17410	COG1063	alcohol dehydrogenase
E5N88_RS17420	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E5N88_RS17440	COG2823	Periplasmic or secreted lipoprotein
E5N88_RS17445	COG0702	epimerase
E5N88_RS17450	COG0693	protein deglycase activity
E5N88_RS17465	COG3153	acetyltransferase
E5N88_RS17470	COG3154	lipid carrier protein
E5N88_RS17475	COG0826	peptidase U32
E5N88_RS17480	COG0826	peptidase U32
E5N88_RS17485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E5N88_RS17490	COG3034	peptidoglycan biosynthetic process
E5N88_RS17500	COG0814	amino acid
E5N88_RS17505	COG0513	Belongs to the DEAD box helicase family
E5N88_RS17575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E5N88_RS17585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E5N88_RS17600	COG1534	Rna-binding protein
E5N88_RS17610	COG2027	D-alanyl-D-alanine carboxypeptidase
E5N88_RS17620	COG0697	spore germination
E5N88_RS17635	COG0142	geranyltranstransferase activity
E5N88_RS17640	COG3423	Transcriptional regulator
E5N88_RS17650	COG5007	Belongs to the BolA IbaG family
E5N88_RS17655	COG3113	response to antibiotic
E5N88_RS17660	COG2854	intermembrane phospholipid transfer
E5N88_RS17665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E5N88_RS17670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E5N88_RS17675	COG1127	ABC transporter
E5N88_RS17680	COG0530	calcium, potassium:sodium antiporter activity
E5N88_RS17695	COG3117	lipopolysaccharide transmembrane transporter activity
E5N88_RS17700	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E5N88_RS17705	COG1137	ATPase activity
E5N88_RS17730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS17735	COG0515	serine threonine protein kinase
E5N88_RS17745	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E5N88_RS17750	COG5002	protein histidine kinase activity
E5N88_RS17750	COG2198	Histidine kinase
E5N88_RS17750	COG0784	Response regulator, receiver
E5N88_RS17755	COG1242	4 iron, 4 sulfur cluster binding
E5N88_RS17760	COG0070	glutamate synthase
E5N88_RS17760	COG0067	glutamate synthase
E5N88_RS17760	COG0069	glutamate synthase activity
E5N88_RS17765	COG0493	'glutamate synthase
E5N88_RS17770	COG4804	nuclease activity
E5N88_RS17775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E5N88_RS17780	COG0402	S-adenosylhomocysteine deaminase activity
E5N88_RS17785	COG2731	YhcH YjgK YiaL family protein
E5N88_RS17815	COG2969	positive regulation of protein catabolic process
E5N88_RS17820	COG0625	glutathione transferase activity
E5N88_RS17845	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E5N88_RS17850	COG3105	Protein conserved in bacteria
E5N88_RS17855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E5N88_RS17865	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
E5N88_RS17885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N88_RS17890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N88_RS17895	COG0471	metal ion transport
E5N88_RS17905	COG2188	Transcriptional regulator
E5N88_RS17930	COG2732	(Barnase) inhibitor
E5N88_RS17950	COG0583	DNA-binding transcription factor activity
E5N88_RS17955	COG0312	modulator of DNA gyrase
E5N88_RS17960	COG3164	Protein of unknown function
E5N88_RS17965	COG1530	ribonuclease E activity
E5N88_RS17975	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E5N88_RS17980	COG1792	Involved in formation and maintenance of cell shape
E5N88_RS17985	COG1077	Cell shape determining protein MreB Mrl
E5N88_RS17990	COG2199	diguanylate cyclase activity
E5N88_RS17990	COG2200	EAL domain
E5N88_RS17995	COG0604	alcohol dehydrogenase
E5N88_RS18010	COG0511	ligase activity, forming carbon-carbon bonds
E5N88_RS18015	COG0439	Biotin carboxylase
E5N88_RS18020	COG3924	membrane
E5N88_RS18025	COG4145	pantothenate transmembrane transporter activity
E5N88_RS18045	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E5N88_RS18060	COG1309	transcriptional regulator
E5N88_RS18065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N88_RS18070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5N88_RS18110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E5N88_RS18130	COG0551	DNA topoisomerase type I activity
E5N88_RS18140	COG0758	DNA mediated transformation
E5N88_RS18170	COG3036	rescue of stalled ribosome
E5N88_RS18175	COG0789	Transcriptional regulator
E5N88_RS18215	COG0201	protein transport
E5N88_RS18295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E5N88_RS18320	COG0051	transcription antitermination factor activity, RNA binding
E5N88_RS18375	COG2964	Protein conserved in bacteria
E5N88_RS18385	COG0545	Peptidyl-prolyl cis-trans isomerase
E5N88_RS18395	COG1047	Peptidyl-prolyl cis-trans
E5N88_RS18400	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E5N88_RS18415	COG0488	(ABC) transporter
E5N88_RS18430	COG0429	hydrolase of the alpha beta-hydrolase fold
E5N88_RS18440	COG3954	Phosphoribulokinase
E5N88_RS18445	COG1765	OsmC-like protein
E5N88_RS18455	COG1289	transmembrane transporter activity
E5N88_RS18490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E5N88_RS18535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E5N88_RS18540	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E5N88_RS18545	COG3266	domain, Protein
E5N88_RS18560	COG4796	Type ii and iii secretion system protein
E5N88_RS18575	COG3166	PFAM Fimbrial assembly family protein
E5N88_RS18580	COG4972	Pilus assembly protein
E5N88_RS18585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E5N88_RS18590	COG0494	nUDIX hydrolase
E5N88_RS18600	COG1011	Hydrolase
E5N88_RS18605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E5N88_RS18615	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5N88_RS18630	COG0745	RESPONSE REGULATOR receiver
E5N88_RS18640	COG2183	response to ionizing radiation
E5N88_RS18645	COG1918	ferrous iron import across plasma membrane
E5N88_RS18660	COG5464	transposase or invertase
E5N88_RS18680	COG2610	gluconate transmembrane transporter activity
E5N88_RS18685	COG1640	4-alpha-glucanotransferase
E5N88_RS18690	COG0058	SHG alpha-glucan phosphorylase activity
E5N88_RS18700	COG3041	Addiction module toxin RelE StbE family
E5N88_RS18705	COG3077	Addiction module antitoxin, RelB DinJ family
E5N88_RS18715	COG1690	Belongs to the RtcB family
E5N88_RS18725	COG4650	regulator
E5N88_RS18730	COG1349	DNA-binding transcription factor activity
E5N88_RS18745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E5N88_RS18760	COG0371	Dehydrogenase
E5N88_RS18770	COG0129	dihydroxy-acid dehydratase activity
E5N88_RS18775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E5N88_RS18780	COG1414	Transcriptional regulator
E5N88_RS18785	COG0058	SHG alpha-glucan phosphorylase activity
E5N88_RS18815	COG2095	MarC family integral membrane protein
E5N88_RS18820	COG2610	gluconate transmembrane transporter activity
E5N88_RS18825	COG3265	gluconokinase activity
E5N88_RS18830	COG1609	Transcriptional regulator
E5N88_RS18835	COG1741	Belongs to the pirin family
E5N88_RS18840	COG0673	inositol 2-dehydrogenase activity
E5N88_RS18845	COG1247	-acetyltransferase
E5N88_RS18850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS18865	COG1735	metal-dependent hydrolase with the TIM-barrel fold
E5N88_RS18870	COG0405	Gamma-glutamyltransferase
E5N88_RS18880	COG0584	glycerophosphoryl diester phosphodiesterase
E5N88_RS18960	COG2177	Part of the ABC transporter FtsEX involved in
E5N88_RS18965	COG2884	Cell division ATP-binding protein ftsE
E5N88_RS18970	COG0552	protein localization to endoplasmic reticulum
E5N88_RS18975	COG0742	ribosomal rna small subunit methyltransferase
E5N88_RS18980	COG3776	membrane
E5N88_RS18990	COG3714	YhhN family
E5N88_RS19010	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E5N88_RS19025	COG0628	permease
E5N88_RS19040	COG0842	Transport permease protein
E5N88_RS19045	COG1129	ABC transporter
E5N88_RS19045	COG0842	Transport permease protein
E5N88_RS19050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N88_RS19055	COG2081	HI0933 family
E5N88_RS19060	COG0306	phosphate transporter
E5N88_RS19090	COG0671	phosphoesterase, PA-phosphatase related
E5N88_RS19095	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E5N88_RS19100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5N88_RS19110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5N88_RS19115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS19120	COG2222	sugar isomerase
E5N88_RS19125	COG2188	Transcriptional regulator
E5N88_RS19145	COG2197	response regulator
E5N88_RS19150	COG0583	DNA-binding transcription factor activity
E5N88_RS19155	COG1295	ribonuclease BN
E5N88_RS19160	COG0477	Major facilitator Superfamily
E5N88_RS19165	COG2982	Protein involved in outer membrane biogenesis
E5N88_RS19170	COG2200	EAL domain
E5N88_RS19175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS19190	COG2199	diguanylate cyclase activity
E5N88_RS19190	COG2200	EAL domain
E5N88_RS19250	COG0814	amino acid
E5N88_RS19255	COG4608	Belongs to the ABC transporter superfamily
E5N88_RS19260	COG0444	Belongs to the ABC transporter superfamily
E5N88_RS19265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E5N88_RS19270	COG0601	transmembrane transport
E5N88_RS19275	COG0747	negative chemotaxis
E5N88_RS19335	COG5571	outer membrane autotransporter
E5N88_RS19340	COG2818	Glycosylase
E5N88_RS19345	COG0456	acetyltransferase
E5N88_RS19350	COG0243	molybdopterin cofactor binding
E5N88_RS19355	COG2885	chlorophyll binding
E5N88_RS19370	COG2944	sequence-specific DNA binding
E5N88_RS19375	COG1278	Cold shock
E5N88_RS19400	COG2801	Transposase and inactivated derivatives
E5N88_RS19425	COG3274	enterobacterial common antigen metabolic process
E5N88_RS19430	COG4682	membrane
E5N88_RS19435	COG1070	Carbohydrate kinase
E5N88_RS19445	COG2207	Transcriptional regulator
E5N88_RS19445	COG1609	Transcriptional regulator
E5N88_RS19450	COG2992	FlgJ-related protein
E5N88_RS19455	COG0366	Alpha amylase catalytic
E5N88_RS19460	COG3977	Valine--pyruvate aminotransferase
E5N88_RS19465	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N88_RS19470	COG1414	Transcriptional regulator
E5N88_RS19480	COG2731	YhcH YjgK YiaL family protein
E5N88_RS19490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E5N88_RS19495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E5N88_RS19500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E5N88_RS19505	COG1070	Carbohydrate kinase
E5N88_RS19510	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E5N88_RS19515	COG3623	hexulose-6-phosphate isomerase
E5N88_RS19520	COG0235	Class ii aldolase
E5N88_RS19535	COG1012	belongs to the aldehyde dehydrogenase family
E5N88_RS19540	COG1940	carbohydrate kinase activity
E5N88_RS19545	COG3276	selenocysteine insertion sequence binding
E5N88_RS19555	COG0625	glutathione transferase activity
E5N88_RS19560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS19560	COG2213	PTS system mannitol-specific
E5N88_RS19570	COG3722	fumarate hydratase activity
E5N88_RS19600	COG2186	Transcriptional regulator
E5N88_RS19610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E5N88_RS19615	COG1609	Transcriptional regulator
E5N88_RS19625	COG2271	Major facilitator Superfamily
E5N88_RS19645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E5N88_RS19650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5N88_RS19660	COG4942	peptidase
E5N88_RS19665	COG2861	carbohydrate metabolic process
E5N88_RS19670	COG1216	Glycosyl transferase, family 2
E5N88_RS19750	COG0438	transferase activity, transferring glycosyl groups
E5N88_RS19755	COG0859	PFAM glycosyl transferase family 9
E5N88_RS19760	COG1519	Transferase
E5N88_RS19790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E5N88_RS19815	COG1561	YicC-like family, N-terminal region
E5N88_RS19820	COG0583	DNA-binding transcription factor activity
E5N88_RS19830	COG2860	membrane
E5N88_RS19850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5N88_RS19855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5N88_RS19860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E5N88_RS19870	COG0786	glutamate:sodium symporter activity
E5N88_RS19875	COG2233	PERMEase
E5N88_RS19880	COG2982	Protein involved in outer membrane biogenesis
E5N88_RS19885	COG1501	Belongs to the glycosyl hydrolase 31 family
E5N88_RS19890	COG2211	Major facilitator Superfamily
E5N88_RS19910	COG0419	ATPase involved in DNA repair
E5N88_RS19935	COG2771	luxR family
E5N88_RS19950	COG3710	Transcriptional regulator
E5N88_RS19960	COG1335	isochorismatase
E5N88_RS19990	COG5464	transposase or invertase
E5N88_RS20005	COG3716	PTS system mannose fructose sorbose family IID component
E5N88_RS20010	COG3715	PTS system
E5N88_RS20015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N88_RS20015	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS20035	COG2723	6-phospho-beta-galactosidase activity
E5N88_RS20070	COG3775	system Galactitol-specific IIC component
E5N88_RS20075	COG3414	Phosphotransferase system galactitol-specific IIB component
E5N88_RS20080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS20080	COG3711	transcriptional antiterminator
E5N88_RS20085	COG2188	Transcriptional regulator
E5N88_RS20120	COG0738	Major facilitator superfamily
E5N88_RS20130	COG1349	DNA-binding transcription factor activity
E5N88_RS20135	COG0440	acetolactate synthase activity
E5N88_RS20140	COG0028	Belongs to the TPP enzyme family
E5N88_RS20165	COG2814	Major facilitator Superfamily
E5N88_RS20175	COG0583	DNA-binding transcription factor activity
E5N88_RS20180	COG2610	gluconate transmembrane transporter activity
E5N88_RS20190	COG0641	radical SAM
E5N88_RS20200	COG2149	membrane
E5N88_RS20220	COG5645	(Lipo)protein
E5N88_RS20225	COG0823	Involved in the tonB-independent uptake of proteins
E5N88_RS20230	COG4235	cytochrome complex assembly
E5N88_RS20230	COG3088	subunit of a heme lyase
E5N88_RS20240	COG1138	Cytochrome C-type biogenesis protein
E5N88_RS20250	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N88_RS20255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N88_RS20260	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N88_RS20270	COG1858	cytochrome C peroxidase
E5N88_RS20285	COG3005	denitrification pathway
E5N88_RS20290	COG0745	RESPONSE REGULATOR receiver
E5N88_RS20295	COG1879	ABC-type sugar transport system periplasmic component
E5N88_RS20300	COG0784	Response regulator, receiver
E5N88_RS20300	COG2198	Histidine kinase
E5N88_RS20300	COG2205	protein histidine kinase activity
E5N88_RS20305	COG2271	Major facilitator Superfamily
E5N88_RS20315	COG0800	Aldolase
E5N88_RS20320	COG3734	2-keto-3-deoxy-galactonokinase
E5N88_RS20325	COG2186	Transcriptional regulator
E5N88_RS20330	COG0561	phosphatase activity
E5N88_RS20335	COG2271	Major facilitator Superfamily
E5N88_RS20340	COG4948	Mandelate Racemase Muconate Lactonizing
E5N88_RS20420	COG2091	lysine biosynthetic process via aminoadipic acid
E5N88_RS20425	COG0431	NADPH-dependent FMN reductase
E5N88_RS20430	COG2252	PERMEase
E5N88_RS20435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5N88_RS20440	COG0704	Plays a role in the regulation of phosphate uptake
E5N88_RS20450	COG0581	inorganic phosphate transmembrane transporter activity
E5N88_RS20455	COG0573	inorganic phosphate transmembrane transporter activity
E5N88_RS20460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E5N88_RS20465	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E5N88_RS20465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N88_RS20465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N88_RS20470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E5N88_RS20475	COG4533	DNA binding
E5N88_RS20535	COG3312	ion transport
E5N88_RS20550	COG0716	FMN binding
E5N88_RS20555	COG1522	sequence-specific DNA binding
E5N88_RS20590	COG1172	Belongs to the binding-protein-dependent transport system permease family
E5N88_RS20600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS20605	COG1609	Transcriptional regulator
E5N88_RS20610	COG0477	Major facilitator Superfamily
E5N88_RS20615	COG2186	Transcriptional regulator
E5N88_RS20675	COG3978	acetolactate synthase activity
E5N88_RS20725	COG3201	nicotinamide mononucleotide transporter
E5N88_RS20745	COG3118	belongs to the thioredoxin family
E5N88_RS20780	COG1088	dTDP-glucose 4,6-dehydratase activity
E5N88_RS20785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E5N88_RS20785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E5N88_RS20790	COG0456	acetyltransferase
E5N88_RS20795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E5N88_RS20800	COG2244	polysaccharide biosynthetic process
E5N88_RS20845	COG3071	HemY protein
E5N88_RS20850	COG2959	enzyme of heme biosynthesis
E5N88_RS20920	COG1011	Hydrolase
E5N88_RS20975	COG2267	carboxylic ester hydrolase activity
E5N88_RS20980	COG0561	phosphatase activity
E5N88_RS21000	COG0641	radical SAM
E5N88_RS21045	COG0805	protein transport
E5N88_RS21090	COG1739	Uncharacterized protein family UPF0029
E5N88_RS21130	COG1763	Mo-molybdopterin cofactor biosynthetic process
E5N88_RS21140	COG3084	Protein conserved in bacteria
E5N88_RS21155	COG0204	Acyl-transferase
E5N88_RS21210	COG0561	phosphatase activity
E5N88_RS21255	COG1501	Belongs to the glycosyl hydrolase 31 family
E5N88_RS21260	COG2017	converts alpha-aldose to the beta-anomer
E5N88_RS21280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS21285	COG1349	DNA-binding transcription factor activity
E5N88_RS21290	COG1011	Hydrolase
E5N88_RS21305	COG0456	acetyltransferase
E5N88_RS21310	COG5499	transcription regulator containing HTH domain
E5N88_RS21315	COG4680	protein conserved in bacteria
E5N88_RS21325	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
E5N88_RS21340	COG2864	formate dehydrogenase
E5N88_RS21345	COG0437	4 iron, 4 sulfur cluster binding
E5N88_RS21375	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E5N88_RS21390	COG1454	alcohol dehydrogenase
E5N88_RS21435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E5N88_RS21450	COG2258	MOSC domain
E5N88_RS21460	COG2205	protein histidine kinase activity
E5N88_RS21465	COG0745	RESPONSE REGULATOR receiver
E5N88_RS21470	COG3678	ATP-independent chaperone mediated protein folding
E5N88_RS21495	COG2211	Major facilitator Superfamily
E5N88_RS21510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5N88_RS21520	COG2134	cdp-diacylglycerol pyrophosphatase
E5N88_RS21530	COG1070	Carbohydrate kinase
E5N88_RS21585	COG3152	Membrane
E5N88_RS21595	COG1494	fructose-1,6-bisphosphatase
E5N88_RS21605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E5N88_RS21620	COG1575	Belongs to the MenA family. Type 1 subfamily
E5N88_RS21635	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E5N88_RS21640	COG1609	Transcriptional regulator
E5N88_RS21645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E5N88_RS21670	COG0626	cystathionine gamma-synthase activity
E5N88_RS21675	COG0527	aspartate kinase activity
E5N88_RS21675	COG0460	homoserine dehydrogenase
E5N88_RS21680	COG0668	transmembrane transport
E5N88_RS21695	COG0737	Belongs to the 5'-nucleotidase family
E5N88_RS21710	COG3738	Protein conserved in bacteria
E5N88_RS21715	COG0371	Dehydrogenase
E5N88_RS21725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS21725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS21725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5N88_RS21730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N88_RS21735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N88_RS21740	COG1882	Formate acetyltransferase
E5N88_RS21745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5N88_RS21750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N88_RS21755	COG2207	Transcriptional regulator
E5N88_RS21790	COG0583	DNA-binding transcription factor activity
E5N88_RS21900	COG0250	Participates in transcription elongation, termination and antitermination
E5N88_RS21970	COG2104	thiamine diphosphate biosynthetic process
E5N88_RS21975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E5N88_RS22085	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E5N88_RS22130	COG3122	Protein conserved in bacteria
E5N88_RS22170	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N88_RS22200	COG2246	polysaccharide biosynthetic process
E5N88_RS22280	COG0527	aspartate kinase activity
E5N88_RS22305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5N88_RS22365	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E5N88_RS22375	COG0534	Mate efflux family protein
E5N88_RS22390	COG0735	belongs to the Fur family
E5N88_RS22440	COG2315	Protein conserved in bacteria
E5N88_RS22505	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5N88_RS22525	COG2252	PERMEase
E5N88_RS22530	COG0025	NhaP-type Na H and K H
E5N88_RS22535	COG0583	DNA-binding transcription factor activity
E5N88_RS22540	COG1380	Effector of murein hydrolase LrgA
E5N88_RS22545	COG1346	cytolysis
E5N88_RS22555	COG3162	membrane
E5N88_RS22570	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E5N88_RS22575	COG0437	4 iron, 4 sulfur cluster binding
E5N88_RS22580	COG3301	Polysulphide reductase, NrfD
E5N88_RS22585	COG1138	Cytochrome C-type biogenesis protein
E5N88_RS22590	COG4235	cytochrome complex assembly
E5N88_RS22595	COG1301	dicarboxylic acid transport
E5N88_RS22600	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E5N88_RS22620	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E5N88_RS22625	COG2824	Alkylphosphonate utilization operon protein PhnA
E5N88_RS22655	COG0531	amino acid
E5N88_RS22660	COG2207	Transcriptional regulator
E5N88_RS22665	COG1982	Orn Lys Arg decarboxylase major
E5N88_RS22670	COG2169	Transcriptional regulator
E5N88_RS22685	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N88_RS22685	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N88_RS22690	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5N88_RS22700	COG4565	transcriptional regulatory protein
E5N88_RS22705	COG3290	protein histidine kinase activity
E5N88_RS22710	COG0243	molybdopterin cofactor binding
E5N88_RS22715	COG0437	4 iron, 4 sulfur cluster binding
E5N88_RS22720	COG3302	dmso reductase anchor subunit
E5N88_RS22725	COG3381	protein complex oligomerization
E5N88_RS22750	COG2197	response regulator
E5N88_RS22785	COG0789	Transcriptional regulator
E5N88_RS22810	COG0305	Participates in initiation and elongation during chromosome replication
E5N88_RS22855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E5N88_RS22945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E5N88_RS23135	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N88_RS23165	COG0739	heme binding
E5N88_RS23175	COG2132	Multicopper oxidase
E5N88_RS23180	COG3667	copper resistance
E5N88_RS23185	COG2372	response to copper ion
E5N88_RS23190	COG1276	copper resistance
E5N88_RS23195	COG0745	RESPONSE REGULATOR receiver
E5N88_RS23200	COG2205	protein histidine kinase activity
E5N88_RS23210	COG0210	DNA helicase
E5N88_RS23220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
E5N88_RS23230	COG1309	transcriptional regulator
E5N88_RS23245	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5N88_RS23250	COG1027	Aspartate ammonia-lyase
E5N88_RS23255	COG3030	protein affecting phage T7 exclusion by the F plasmid
E5N88_RS23260	COG0531	amino acid
E5N88_RS23300	COG5510	response to toxic substance
E5N88_RS23330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E5N88_RS23335	COG1053	succinate dehydrogenase
E5N88_RS23355	COG1511	domain protein
E5N88_RS23355	COG3264	Mechanosensitive ion channel
E5N88_RS23375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N88_RS23400	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E5N88_RS23400	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E5N88_RS23405	COG0802	atpase or kinase
E5N88_RS23430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E5N88_RS23435	COG0330	HflC and HflK could
E5N88_RS23440	COG0330	HflC and HflK could
E5N88_RS23445	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E5N88_RS23460	COG0557	exoribonuclease II activity
E5N88_RS23470	COG3789	protein conserved in bacteria
E5N88_RS23490	COG3766	membrane
E5N88_RS23495	COG5463	Belongs to the UPF0441 family
E5N88_RS23500	COG0754	glutathionylspermidine amidase activity
E5N88_RS23505	COG1960	acyl-CoA dehydrogenase activity
E5N88_RS23515	COG3650	response to hydrogen peroxide
E5N88_RS23520	COG1073	alpha beta
E5N88_RS23590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E5N88_RS23605	COG3061	Opacity-associated protein A
E5N88_RS23610	COG0545	Peptidyl-prolyl cis-trans isomerase
E5N88_RS23615	COG1113	amino acid transport
E5N88_RS23625	COG0697	spore germination
E5N88_RS23645	COG1733	regulation of RNA biosynthetic process
E5N88_RS23660	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E5N88_RS23670	COG1253	flavin adenine dinucleotide binding
E5N88_RS23690	COG2105	PFAM AIG2 family protein
E5N88_RS23695	COG2271	Major facilitator Superfamily
E5N88_RS23700	COG3964	amidohydrolase
E5N88_RS23715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E5N88_RS23720	COG0837	glucose binding
E5N88_RS23720	COG1737	Transcriptional regulator
E5N88_RS23725	COG0477	Major facilitator Superfamily
E5N88_RS23725	COG2814	Major facilitator Superfamily
E5N88_RS23735	COG2814	Major facilitator Superfamily
E5N88_RS23735	COG0477	Major facilitator Superfamily
E5N88_RS23740	COG3718	enzyme involved in inositol metabolism
E5N88_RS23780	COG5520	Belongs to the glycosyl hydrolase 30 family
E5N88_RS23785	COG1082	Xylose isomerase domain protein TIM barrel
E5N88_RS23795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N88_RS23800	COG3962	Belongs to the TPP enzyme family
E5N88_RS23805	COG0673	inositol 2-dehydrogenase activity
E5N88_RS23810	COG2814	Major facilitator Superfamily
E5N88_RS23820	COG1082	Xylose isomerase domain protein TIM barrel
E5N88_RS23830	COG0312	modulator of DNA gyrase
E5N88_RS23865	COG3964	amidohydrolase
E5N88_RS23880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N88_RS23880	COG3711	transcriptional antiterminator
E5N88_RS23885	COG3077	Addiction module antitoxin, RelB DinJ family
E5N88_RS23890	COG2026	Addiction module toxin, RelE StbE family
E5N88_RS23905	COG0366	Alpha amylase catalytic
E5N88_RS23960	COG1438	arginine binding
E5N88_RS23965	COG1288	antiporter activity
E5N88_RS23985	COG2731	YhcH YjgK YiaL family protein
E5N88_RS24025	COG2927	DNA polymerase III (CHI subunit)
E5N88_RS24035	COG0795	lipopolysaccharide-transporting ATPase activity
E5N88_RS24040	COG0795	lipopolysaccharide-transporting ATPase activity
E5N88_RS24045	COG1609	Transcriptional regulator
E5N88_RS24050	COG2610	gluconate transmembrane transporter activity
E5N88_RS24055	COG1028	Short-chain dehydrogenase reductase Sdr
E5N88_RS24060	COG1063	alcohol dehydrogenase
E5N88_RS24065	COG3265	gluconokinase activity
E5N88_RS24070	COG1064	alcohol dehydrogenase
E5N88_RS24080	COG0582	viral genome integration into host DNA
E5N88_RS24085	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E5N88_RS24085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5N88_RS24110	COG4133	protoheme IX ABC transporter activity
E5N88_RS24145	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E5N88_RS24175	COG0412	Dienelactone hydrolase
E5N88_RS24180	COG2186	Transcriptional regulator
E5N88_RS24200	COG0583	DNA-binding transcription factor activity
E5N88_RS24205	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5N88_RS24210	COG0700	Nucleoside recognition
E5N88_RS24215	COG3366	ferrous iron transmembrane transporter activity
E5N88_RS24220	COG0477	Major facilitator Superfamily
E5N88_RS24225	COG2733	membrane
E5N88_RS24235	COG5464	transposase or invertase
E5N88_RS24240	COG1012	belongs to the aldehyde dehydrogenase family
E5N88_RS24275	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
E5N88_RS24280	COG1715	Restriction endonuclease
E5N88_RS24295	COG0523	cobalamin synthesis protein
E5N88_RS24300	COG2879	small protein
E5N88_RS24305	COG1966	Carbon starvation protein
E5N88_RS24310	COG0840	transmembrane signaling receptor activity
E5N88_RS24325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N88_RS24330	COG3715	PTS system
E5N88_RS24335	COG3716	PTS system mannose fructose sorbose family IID component
E5N88_RS24340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E5N88_RS24360	COG1484	DNA-dependent DNA replication
E5N88_RS24375	COG2966	Psort location CytoplasmicMembrane, score
E5N88_RS24380	COG2197	response regulator
E5N88_RS24385	COG2197	response regulator
E5N88_RS24390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E5N88_RS24395	COG4114	ferric iron reductase
E5N88_RS24400	COG3706	GGDEF domain
E5N88_RS24430	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E5N88_RS24440	COG1011	Hydrolase
E5N88_RS24450	COG2823	Periplasmic or secreted lipoprotein
E5N88_RS24460	COG4667	esterase of the alpha-beta hydrolase superfamily
E5N88_RS24465	COG0084	hydrolase, TatD family'
E5N88_RS24470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5N88_RS24475	COG1328	CTP reductase activity
E5N88_RS24505	COG3188	usher protein
E5N88_RS24510	COG3121	Chaperone
E5N88_RS24515	COG3539	Fimbrial protein
E5N88_RS24530	COG3726	membrane protein affecting hemolysin expression
E5N88_RS24535	COG0560	Phosphoserine phosphatase
E5N88_RS24550	COG0488	(ABC) transporter
E5N88_RS24575	COG2207	Transcriptional regulator
E5N88_RS24575	COG3708	Transcriptional regulator
E5N88_RS24580	COG3045	CreA protein
E5N88_RS24585	COG0745	RESPONSE REGULATOR receiver
E5N88_RS24590	COG2205	protein histidine kinase activity
E5N88_RS24595	COG4452	Inner membrane protein CreD
E5N88_RS24615	COG3121	Chaperone
E5N88_RS24635	COG0745	RESPONSE REGULATOR receiver
E5N88_RS24645	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E5N88_RS24920	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
E5N88_RS25005	COG3300	MHYT domain
E5N88_RS25005	COG5001	Diguanylate cyclase
E5N88_RS25105	COG4974	Belongs to the 'phage' integrase family
E5N88_RS25275	COG0616	signal peptide processing
E5N88_RS25490	COG1192	Involved in chromosome partitioning
E5N88_RS25570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E5N88_RS25645	COG1196	nuclear chromosome segregation
E5N88_RS25750	COG1660	Displays ATPase and GTPase activities
E5N88_RS25770	COG2194	sulfuric ester hydrolase activity
E5N88_RS25775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E5N88_RS25885	COG1278	Cold shock