locus-tag	class	description
E5O17_RS00005	COG0460	homoserine dehydrogenase
E5O17_RS00005	COG0527	aspartate kinase activity
E5O17_RS00015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E5O17_RS00025	COG1115	amino acid carrier protein
E5O17_RS00035	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5O17_RS00040	COG1584	GPR1 FUN34 yaaH family protein
E5O17_RS00045	COG4735	regulation of single-species biofilm formation
E5O17_RS00110	COG3188	usher protein
E5O17_RS00125	COG3539	Fimbrial protein
E5O17_RS00130	COG3121	Chaperone
E5O17_RS00150	COG0583	DNA-binding transcription factor activity
E5O17_RS00165	COG0737	Belongs to the 5'-nucleotidase family
E5O17_RS00175	COG3119	arylsulfatase activity
E5O17_RS00180	COG0641	radical SAM
E5O17_RS00200	COG0583	DNA-binding transcription factor activity
E5O17_RS00225	COG0196	riboflavin kinase activity
E5O17_RS00240	COG1047	Peptidyl-prolyl cis-trans
E5O17_RS00395	COG2271	Major facilitator Superfamily
E5O17_RS00415	COG3119	arylsulfatase activity
E5O17_RS00480	COG0417	DNA replication proofreading
E5O17_RS00520	COG0586	Pfam SNARE associated Golgi protein
E5O17_RS00610	COG0768	penicillin binding
E5O17_RS00620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E5O17_RS00635	COG0772	Belongs to the SEDS family
E5O17_RS00660	COG0849	cell division
E5O17_RS00665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E5O17_RS00685	COG0494	nUDIX hydrolase
E5O17_RS00720	COG1459	type II secretion system
E5O17_RS00725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E5O17_RS00730	COG4969	Belongs to the N-Me-Phe pilin family
E5O17_RS00745	COG3725	Membrane protein required for beta-lactamase induction
E5O17_RS00750	COG3940	Belongs to the glycosyl hydrolase 43 family
E5O17_RS00755	COG2211	Major facilitator Superfamily
E5O17_RS00770	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E5O17_RS00775	COG0508	dehydrogenase complex catalyzes the overall conversion of
E5O17_RS00780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5O17_RS00795	COG3064	Membrane
E5O17_RS00830	COG1349	DNA-binding transcription factor activity
E5O17_RS00855	COG4993	Dehydrogenase
E5O17_RS00865	COG0288	reversible hydration of carbon dioxide
E5O17_RS00870	COG1131	(ABC) transporter
E5O17_RS00875	COG0842	Transport permease protein
E5O17_RS00880	COG3539	Fimbrial protein
E5O17_RS00900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS00905	COG0726	polysaccharide deacetylase
E5O17_RS00925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5O17_RS00950	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E5O17_RS00955	COG1643	Atp-dependent helicase
E5O17_RS00960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E5O17_RS00965	COG4774	siderophore transport
E5O17_RS00970	COG1120	ATPase activity
E5O17_RS00975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E5O17_RS00990	COG3188	usher protein
E5O17_RS00995	COG3121	Chaperone
E5O17_RS01000	COG3539	Fimbrial protein
E5O17_RS01005	COG3539	Fimbrial protein
E5O17_RS01035	COG2860	membrane
E5O17_RS01060	COG3835	regulator
E5O17_RS01070	COG0477	Major facilitator Superfamily
E5O17_RS01120	COG0575	Belongs to the CDS family
E5O17_RS01185	COG0346	lactoylglutathione lyase activity
E5O17_RS01195	COG4568	rho-dependent transcription termination
E5O17_RS01210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E5O17_RS01215	COG3015	lipoprotein NlpE involved in copper resistance
E5O17_RS01225	COG1720	tRNA m6t6A37 methyltransferase activity
E5O17_RS01290	COG0583	DNA-binding transcription factor activity
E5O17_RS01295	COG2814	Major facilitator Superfamily
E5O17_RS01305	COG2226	methyltransferase
E5O17_RS01310	COG0741	lytic transglycosylase activity
E5O17_RS01310	COG1388	LysM domain
E5O17_RS01320	COG2226	methyltransferase
E5O17_RS01425	COG2885	chlorophyll binding
E5O17_RS01425	COG3047	cAMP biosynthetic process
E5O17_RS01460	COG3501	Rhs element vgr protein
E5O17_RS01470	COG3209	COG3209 Rhs family protein
E5O17_RS01490	COG3209	COG3209 Rhs family protein
E5O17_RS01560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5O17_RS01575	COG0121	glutamine amidotransferase
E5O17_RS01580	COG3034	peptidoglycan biosynthetic process
E5O17_RS01595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E5O17_RS01600	COG2195	Cleaves the N-terminal amino acid of tripeptides
E5O17_RS01645	COG0582	viral genome integration into host DNA
E5O17_RS01785	COG2814	Major facilitator Superfamily
E5O17_RS01800	COG0179	Fumarylacetoacetate (FAA) hydrolase
E5O17_RS01835	COG3188	usher protein
E5O17_RS01840	COG3121	Chaperone
E5O17_RS01845	COG3539	Fimbrial protein
E5O17_RS01860	COG2200	EAL domain
E5O17_RS01905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O17_RS01915	COG0789	Transcriptional regulator
E5O17_RS01925	COG2814	Major facilitator Superfamily
E5O17_RS01945	COG1271	oxidase subunit
E5O17_RS01950	COG1294	oxidase, subunit
E5O17_RS01970	COG1280	lysine exporter protein (LysE YggA)
E5O17_RS02005	COG0113	porphobilinogen synthase activity
E5O17_RS02020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E5O17_RS02025	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E5O17_RS02070	COG3706	GGDEF domain
E5O17_RS02075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E5O17_RS02095	COG4126	flavin adenine dinucleotide binding
E5O17_RS02110	COG1940	carbohydrate kinase activity
E5O17_RS02115	COG2814	Major facilitator Superfamily
E5O17_RS02120	COG0419	ATPase involved in DNA repair
E5O17_RS02125	COG0420	3'-5' exonuclease activity
E5O17_RS02135	COG5002	protein histidine kinase activity
E5O17_RS02150	COG0366	Alpha amylase catalytic
E5O17_RS02155	COG0450	alkyl hydroperoxide reductase
E5O17_RS02175	COG1862	Preprotein translocase
E5O17_RS02185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E5O17_RS02225	COG4238	major outer membrane lipoprotein
E5O17_RS02235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5O17_RS02235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5O17_RS02255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E5O17_RS02260	COG0667	Aldo Keto reductase
E5O17_RS02270	COG0142	geranyltranstransferase activity
E5O17_RS02305	COG2188	Transcriptional regulator
E5O17_RS02335	COG2814	Major facilitator Superfamily
E5O17_RS02360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E5O17_RS02365	COG1845	cytochrome c oxidase, subunit III
E5O17_RS02370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E5O17_RS02375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E5O17_RS02380	COG2223	nitrite transmembrane transporter activity
E5O17_RS02385	COG3056	Lipoprotein
E5O17_RS02390	COG0271	Belongs to the BolA IbaG family
E5O17_RS02415	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E5O17_RS02425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E5O17_RS02430	COG1555	photosystem II stabilization
E5O17_RS02435	COG0824	Thioesterase
E5O17_RS02445	COG4533	DNA binding
E5O17_RS02465	COG1522	sequence-specific DNA binding
E5O17_RS02470	COG1132	(ABC) transporter
E5O17_RS02475	COG1132	(ABC) transporter
E5O17_RS02485	COG0347	Belongs to the P(II) protein family
E5O17_RS02490	COG0004	ammonium transporteR
E5O17_RS02495	COG1946	Acyl-CoA thioesterase
E5O17_RS02500	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E5O17_RS02505	COG3695	enzyme binding
E5O17_RS02515	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5O17_RS02535	COG0110	maltose O-acetyltransferase activity
E5O17_RS02550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5O17_RS02555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O17_RS02560	COG1309	transcriptional regulator
E5O17_RS02565	COG1196	nuclear chromosome segregation
E5O17_RS02565	COG3264	Mechanosensitive ion channel
E5O17_RS02570	COG5464	transposase or invertase
E5O17_RS02580	COG3923	Primosomal replication protein n
E5O17_RS02585	COG2832	Protein of unknown function (DUF454)
E5O17_RS02630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS02635	COG4651	solute:proton antiporter activity
E5O17_RS02635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E5O17_RS02640	COG2223	nitrite transmembrane transporter activity
E5O17_RS02655	COG3735	TraB family
E5O17_RS02675	COG1585	Membrane protein implicated in regulation of membrane protease activity
E5O17_RS02680	COG0330	HflC and HflK could
E5O17_RS02685	COG4619	ABC transporter
E5O17_RS02690	COG0390	transport system, permease component
E5O17_RS02695	COG3118	belongs to the thioredoxin family
E5O17_RS02700	COG0300	oxidoreductase activity
E5O17_RS02705	COG2755	lipolytic protein G-D-S-L family
E5O17_RS02710	COG4181	ATPase activity
E5O17_RS02715	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E5O17_RS02725	COG1464	Belongs to the NlpA lipoprotein family
E5O17_RS02760	COG3960	tartronate-semialdehyde synthase activity
E5O17_RS02765	COG3622	Belongs to the hyi family
E5O17_RS02770	COG2084	Dehydrogenase
E5O17_RS02780	COG1953	Uracil, thiamine, allantoin
E5O17_RS02790	COG2233	PERMEase
E5O17_RS02795	COG1929	Belongs to the glycerate kinase type-1 family
E5O17_RS02800	COG3257	ureidoglycine aminohydrolase activity
E5O17_RS02805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E5O17_RS02810	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E5O17_RS02815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5O17_RS02820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5O17_RS02830	COG0549	Belongs to the carbamate kinase family
E5O17_RS02835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E5O17_RS02840	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E5O17_RS02850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E5O17_RS02870	COG1988	membrane-bound metal-dependent
E5O17_RS02875	COG2501	S4 domain
E5O17_RS02960	COG0463	Glycosyl transferase, family 2
E5O17_RS02965	COG2246	polysaccharide biosynthetic process
E5O17_RS02975	COG5002	protein histidine kinase activity
E5O17_RS02985	COG2207	Transcriptional regulator
E5O17_RS02990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5O17_RS03000	COG3059	membrane
E5O17_RS03010	COG1113	amino acid transport
E5O17_RS03015	COG0668	transmembrane transport
E5O17_RS03025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E5O17_RS03025	COG3933	PFAM sigma-54 factor interaction domain-containing protein
E5O17_RS03030	COG2222	sugar isomerase
E5O17_RS03040	COG3716	PTS system mannose fructose sorbose family IID component
E5O17_RS03065	COG2315	Protein conserved in bacteria
E5O17_RS03095	COG4771	TonB-dependent receptor
E5O17_RS03100	COG2382	esterase
E5O17_RS03105	COG3251	PFAM MbtH domain protein
E5O17_RS03110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E5O17_RS03110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E5O17_RS03115	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E5O17_RS03120	COG1120	ATPase activity
E5O17_RS03125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5O17_RS03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5O17_RS03140	COG4592	Periplasmic binding protein
E5O17_RS03145	COG1169	isochorismate synthase
E5O17_RS03150	COG1021	2,3-dihydroxybenzoate-AMP ligase
E5O17_RS03155	COG3433	isochorismatase activity
E5O17_RS03155	COG1535	isochorismatase
E5O17_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
E5O17_RS03170	COG1966	Carbon starvation protein
E5O17_RS03175	COG2879	small protein
E5O17_RS03180	COG0371	Dehydrogenase
E5O17_RS03185	COG0436	Aminotransferase
E5O17_RS03190	COG1475	DNA binding
E5O17_RS03195	COG3969	phosphoadenosine phosphosulfate
E5O17_RS03200	COG0583	DNA-binding transcription factor activity
E5O17_RS03205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5O17_RS03225	COG0243	molybdopterin cofactor binding
E5O17_RS03245	COG1063	alcohol dehydrogenase
E5O17_RS03250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E5O17_RS03255	COG3719	Belongs to the RNase T2 family
E5O17_RS03260	COG0471	metal ion transport
E5O17_RS03275	COG3051	citrate lyase alpha subunit
E5O17_RS03280	COG2301	Belongs to the HpcH HpaI aldolase family
E5O17_RS03290	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E5O17_RS03295	COG3290	protein histidine kinase activity
E5O17_RS03300	COG4565	transcriptional regulatory protein
E5O17_RS03305	COG3069	C4-dicarboxylate transmembrane transporter activity
E5O17_RS03325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5O17_RS03340	COG0583	DNA-binding transcription factor activity
E5O17_RS03355	COG1686	Belongs to the peptidase S11 family
E5O17_RS03365	COG0772	Belongs to the SEDS family
E5O17_RS03370	COG0768	penicillin binding
E5O17_RS03380	COG0799	negative regulation of ribosome biogenesis
E5O17_RS03400	COG1466	dna polymerase III delta subunit
E5O17_RS03430	COG3290	protein histidine kinase activity
E5O17_RS03430	COG3829	transcription factor binding
E5O17_RS03435	COG2888	peptidyl-tyrosine sulfation
E5O17_RS03450	COG2214	Heat shock protein DnaJ domain protein
E5O17_RS03460	COG2214	Heat shock protein DnaJ domain protein
E5O17_RS03465	COG0443	Heat shock 70 kDa protein
E5O17_RS03480	COG1126	abc transporter atp-binding protein
E5O17_RS03485	COG0765	amino acid transport
E5O17_RS03490	COG0765	amino acid transport
E5O17_RS03515	COG1702	phosphate starvation-inducible protein PhoH
E5O17_RS03525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5O17_RS03570	COG0367	asparagine synthase
E5O17_RS03575	COG0647	UMP catabolic process
E5O17_RS03580	COG1940	carbohydrate kinase activity
E5O17_RS03580	COG1846	Transcriptional regulator
E5O17_RS03585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5O17_RS03625	COG1053	succinate dehydrogenase
E5O17_RS03630	COG0583	DNA-binding transcription factor activity
E5O17_RS03635	COG0735	belongs to the Fur family
E5O17_RS03650	COG0596	Alpha beta hydrolase
E5O17_RS03660	COG0033	Phosphoglucomutase
E5O17_RS03670	COG0531	amino acid
E5O17_RS03675	COG1982	Orn Lys Arg decarboxylase major
E5O17_RS03685	COG0745	RESPONSE REGULATOR receiver
E5O17_RS03690	COG2205	protein histidine kinase activity
E5O17_RS03735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E5O17_RS03740	COG1984	allophanate hydrolase subunit 2
E5O17_RS03755	COG0582	viral genome integration into host DNA
E5O17_RS03795	COG1216	Glycosyl transferase, family 2
E5O17_RS03820	COG3180	Ammonia monooxygenase
E5O17_RS03835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E5O17_RS03850	COG0567	Dehydrogenase, E1 component
E5O17_RS03855	COG0508	dehydrogenase complex catalyzes the overall conversion of
E5O17_RS03865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5O17_RS03870	COG1271	oxidase subunit
E5O17_RS03875	COG1294	oxidase, subunit
E5O17_RS03880	COG4890	Cyd operon protein YbgT
E5O17_RS03885	COG3790	cyd operon protein YbgE
E5O17_RS03890	COG0824	Thioesterase
E5O17_RS03895	COG0811	peptide transport
E5O17_RS03900	COG0848	biopolymer transport protein
E5O17_RS03905	COG3064	Membrane
E5O17_RS03915	COG2885	chlorophyll binding
E5O17_RS03920	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E5O17_RS03980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E5O17_RS03985	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O17_RS03985	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O17_RS03990	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O17_RS03995	COG0583	DNA-binding transcription factor activity
E5O17_RS04000	COG0583	DNA-binding transcription factor activity
E5O17_RS04005	COG0471	metal ion transport
E5O17_RS04005	COG0490	domain, Protein
E5O17_RS04030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5O17_RS04035	COG1120	ATPase activity
E5O17_RS04045	COG2017	converts alpha-aldose to the beta-anomer
E5O17_RS04070	COG1119	ATPase activity
E5O17_RS04075	COG3585	molybdate ion transport
E5O17_RS04075	COG2005	Transcriptional regulator
E5O17_RS04085	COG0725	ABC transporter, periplasmic molybdate-binding protein
E5O17_RS04090	COG4149	molybdate abc transporter
E5O17_RS04100	COG0561	phosphatase activity
E5O17_RS04110	COG4677	pectinesterase activity
E5O17_RS04140	COG1881	PFAM PEBP family protein
E5O17_RS04200	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5O17_RS04210	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E5O17_RS04220	COG0670	Belongs to the BI1 family
E5O17_RS04250	COG0392	lysyltransferase activity
E5O17_RS04260	COG3568	Endonuclease Exonuclease Phosphatase
E5O17_RS04270	COG0842	Transport permease protein
E5O17_RS04275	COG0842	Transport permease protein
E5O17_RS04280	COG1131	(ABC) transporter
E5O17_RS04290	COG1309	transcriptional regulator
E5O17_RS04295	COG0513	Belongs to the DEAD box helicase family
E5O17_RS04305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E5O17_RS04315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E5O17_RS04325	COG0668	transmembrane transport
E5O17_RS04330	COG1126	abc transporter atp-binding protein
E5O17_RS04335	COG0765	amino acid transport
E5O17_RS04340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O17_RS04355	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E5O17_RS04360	COG2194	sulfuric ester hydrolase activity
E5O17_RS04375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E5O17_RS04380	COG1376	ErfK ybiS ycfS ynhG family protein
E5O17_RS04385	COG0488	(ABC) transporter
E5O17_RS04405	COG0561	phosphatase activity
E5O17_RS04410	COG1882	Formate acetyltransferase
E5O17_RS04415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5O17_RS04465	COG2301	Belongs to the HpcH HpaI aldolase family
E5O17_RS04485	COG1960	acyl-CoA dehydrogenase activity
E5O17_RS04495	COG0583	DNA-binding transcription factor activity
E5O17_RS04500	COG2610	gluconate transmembrane transporter activity
E5O17_RS04505	COG2133	pyrroloquinoline quinone binding
E5O17_RS04510	COG0625	glutathione transferase activity
E5O17_RS04515	COG1686	Belongs to the peptidase S11 family
E5O17_RS04520	COG1349	DNA-binding transcription factor activity
E5O17_RS04525	COG0671	phosphoesterase, PA-phosphatase related
E5O17_RS04530	COG2814	Major facilitator Superfamily
E5O17_RS04535	COG0561	phosphatase activity
E5O17_RS04540	COG0738	Major facilitator superfamily
E5O17_RS04545	COG3226	Transcriptional regulator
E5O17_RS04590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E5O17_RS04595	COG3842	ATPase activity
E5O17_RS04600	COG1176	ABC-type spermidine putrescine transport system, permease component I
E5O17_RS04605	COG1177	transmembrane transport
E5O17_RS04635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O17_RS04640	COG4160	amino acid transport
E5O17_RS04645	COG4215	(ABC) transporter
E5O17_RS04650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O17_RS04655	COG1126	abc transporter atp-binding protein
E5O17_RS04670	COG3023	N-Acetylmuramoyl-L-alanine amidase
E5O17_RS04675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5O17_RS04680	COG0702	epimerase
E5O17_RS04685	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E5O17_RS04690	COG0028	Belongs to the TPP enzyme family
E5O17_RS04695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5O17_RS04705	COG2431	L-lysine efflux transmembrane transporter activity
E5O17_RS04710	COG3593	DNA synthesis involved in DNA repair
E5O17_RS04715	COG2990	Protein conserved in bacteria
E5O17_RS04720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O17_RS04730	COG1278	Cold shock
E5O17_RS04740	COG0542	response to heat
E5O17_RS04765	COG1335	isochorismatase
E5O17_RS04775	COG0583	DNA-binding transcription factor activity
E5O17_RS04795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E5O17_RS04800	COG4988	ABC transporter
E5O17_RS04805	COG0492	ferredoxin-NADP+ reductase activity
E5O17_RS04825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E5O17_RS04835	COG0243	molybdopterin cofactor binding
E5O17_RS04840	COG0437	4 iron, 4 sulfur cluster binding
E5O17_RS04845	COG3302	dmso reductase anchor subunit
E5O17_RS04855	COG0531	amino acid
E5O17_RS04860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5O17_RS04875	COG1882	Formate acetyltransferase
E5O17_RS04880	COG2116	formate transmembrane transporter activity
E5O17_RS04885	COG1944	ATP diphosphatase activity
E5O17_RS04890	COG2323	membrane
E5O17_RS04905	COG0501	Belongs to the peptidase M48B family
E5O17_RS04915	COG0539	negative regulation of cytoplasmic translation
E5O17_RS04925	COG0658	competence protein
E5O17_RS04925	COG2333	competence protein COMEC
E5O17_RS04940	COG3214	Protein conserved in bacteria
E5O17_RS04955	COG3173	Aminoglycoside phosphotransferase
E5O17_RS04960	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E5O17_RS04965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E5O17_RS04975	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E5O17_RS04985	COG2989	Protein conserved in bacteria
E5O17_RS04990	COG3108	Peptidase M15
E5O17_RS04995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E5O17_RS05015	COG1522	sequence-specific DNA binding
E5O17_RS05030	COG1115	amino acid carrier protein
E5O17_RS05040	COG0582	viral genome integration into host DNA
E5O17_RS05060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O17_RS05095	COG1484	DNA-dependent DNA replication
E5O17_RS05200	COG4220	transposase activity
E5O17_RS05255	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O17_RS05280	COG2135	peptidase activity
E5O17_RS05300	COG0308	aminopeptidase N
E5O17_RS05315	COG3217	Mosc domain protein beta barrel domain protein
E5O17_RS05315	COG0633	Ferredoxin
E5O17_RS05325	COG0488	(ABC) transporter
E5O17_RS05330	COG2995	paraquat-inducible protein a
E5O17_RS05335	COG3008	intermembrane lipid transfer
E5O17_RS05335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E5O17_RS05340	COG3009	Protein conserved in bacteria
E5O17_RS05345	COG3130	regulation of translation
E5O17_RS05355	COG1067	ATP-dependent peptidase activity
E5O17_RS05375	COG3070	regulator of competence-specific genes
E5O17_RS05380	COG1289	transmembrane transporter activity
E5O17_RS05385	COG3304	Inner membrane component domain
E5O17_RS05390	COG0210	DNA helicase
E5O17_RS05405	COG1832	CoA-binding protein
E5O17_RS05420	COG1881	PFAM PEBP family protein
E5O17_RS05440	COG0670	Belongs to the BI1 family
E5O17_RS05490	COG2205	protein histidine kinase activity
E5O17_RS05495	COG0745	RESPONSE REGULATOR receiver
E5O17_RS05510	COG2368	4-hydroxyphenylacetate
E5O17_RS05515	COG1846	Transcriptional regulator
E5O17_RS05525	COG1012	belongs to the aldehyde dehydrogenase family
E5O17_RS05530	COG3384	dioxygenase
E5O17_RS05540	COG3971	2-oxopent-4-enoate hydratase activity
E5O17_RS05585	COG4232	protein-disulfide reductase activity
E5O17_RS05590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5O17_RS05590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E5O17_RS05595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E5O17_RS05615	COG3729	General stress protein
E5O17_RS05620	COG1309	transcriptional regulator
E5O17_RS05640	COG1702	phosphate starvation-inducible protein PhoH
E5O17_RS05645	COG1737	Transcriptional regulator
E5O17_RS05650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E5O17_RS05670	COG2814	Major facilitator Superfamily
E5O17_RS05675	COG0673	inositol 2-dehydrogenase activity
E5O17_RS05710	COG3381	protein complex oligomerization
E5O17_RS05765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5O17_RS05785	COG5645	(Lipo)protein
E5O17_RS05800	COG1560	Kdo2-lipid A biosynthetic process
E5O17_RS05815	COG3038	cytochrome b561
E5O17_RS05850	COG2999	glutathione oxidoreductase activity
E5O17_RS05860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5O17_RS05950	COG1530	ribonuclease E activity
E5O17_RS06010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5O17_RS06015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E5O17_RS06020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E5O17_RS06030	COG0470	DNA polymerase III
E5O17_RS06035	COG0084	hydrolase, TatD family'
E5O17_RS06045	COG4773	Receptor
E5O17_RS06050	COG0537	adenosine 5'-monophosphoramidase activity
E5O17_RS06055	COG5633	Lipoprotein
E5O17_RS06080	COG1252	NADH dehydrogenase
E5O17_RS06085	COG3134	Outer membrane lipoprotein
E5O17_RS06090	COG1309	transcriptional regulator
E5O17_RS06100	COG1388	LysM domain
E5O17_RS06100	COG1376	ErfK ybiS ycfS ynhG family protein
E5O17_RS06105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E5O17_RS06110	COG4591	ABC-type transport system involved in lipoprotein release permease component
E5O17_RS06115	COG1136	(ABC) transporter
E5O17_RS06120	COG4591	ABC-type transport system involved in lipoprotein release permease component
E5O17_RS06140	COG1177	transmembrane transport
E5O17_RS06170	COG2850	peptidyl-arginine hydroxylation
E5O17_RS06185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E5O17_RS06215	COG0538	isocitrate dehydrogenase activity
E5O17_RS06285	COG0071	Belongs to the small heat shock protein (HSP20) family
E5O17_RS06295	COG3038	cytochrome b561
E5O17_RS06325	COG1124	(ABC) transporter
E5O17_RS06330	COG0668	transmembrane transport
E5O17_RS06345	COG3443	Belongs to the bacterial solute-binding protein 9 family
E5O17_RS06360	COG0789	Transcriptional regulator
E5O17_RS06375	COG1605	Chorismate mutase
E5O17_RS06385	COG3615	Tellurite resistance protein tehB
E5O17_RS06405	COG2261	transglycosylase associated protein
E5O17_RS06415	COG3042	response to heat
E5O17_RS06425	COG3189	MarR family transcriptional regulator
E5O17_RS06430	COG2807	transmembrane transport
E5O17_RS06435	COG2207	Transcriptional regulator
E5O17_RS06450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E5O17_RS06455	COG2199	diguanylate cyclase activity
E5O17_RS06465	COG2766	serine protein kinase
E5O17_RS06470	COG3713	MltA-interacting MipA family protein
E5O17_RS06475	COG0641	radical SAM
E5O17_RS06480	COG0656	L-ascorbic acid biosynthetic process
E5O17_RS06500	COG3139	Protein of unknown function (DUF1315)
E5O17_RS06505	COG1335	isochorismatase
E5O17_RS06510	COG0252	asparaginase activity
E5O17_RS06515	COG0616	signal peptide processing
E5O17_RS06520	COG0778	Nitroreductase
E5O17_RS06545	COG0494	nUDIX hydrolase
E5O17_RS06580	COG3678	ATP-independent chaperone mediated protein folding
E5O17_RS06595	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5O17_RS06605	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E5O17_RS06610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E5O17_RS06615	COG1447	Phosphotransferase system cellobiose-specific component IIA
E5O17_RS06620	COG1917	Cupin 2, conserved barrel domain protein
E5O17_RS06620	COG2169	Transcriptional regulator
E5O17_RS06625	COG1486	melibiose metabolic process
E5O17_RS06635	COG0753	catalase activity
E5O17_RS06650	COG1988	membrane-bound metal-dependent
E5O17_RS06655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5O17_RS06665	COG3001	Fructosamine kinase
E5O17_RS06675	COG1105	Belongs to the carbohydrate kinase PfkB family
E5O17_RS06680	COG3137	Salt-induced outer membrane protein
E5O17_RS06760	COG0386	Belongs to the glutathione peroxidase family
E5O17_RS06770	COG0791	NLP P60 protein
E5O17_RS06785	COG4256	Hemin uptake protein
E5O17_RS06800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5O17_RS06800	COG0574	Belongs to the PEP-utilizing enzyme family
E5O17_RS06805	COG0318	PFAM AMP-dependent synthetase and ligase
E5O17_RS06810	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E5O17_RS06815	COG0644	oxidoreductase
E5O17_RS06820	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E5O17_RS06825	COG2086	electron transfer activity
E5O17_RS06830	COG2207	Transcriptional regulator
E5O17_RS06830	COG1917	Cupin 2, conserved barrel domain protein
E5O17_RS06835	COG1960	acyl-CoA dehydrogenase activity
E5O17_RS06840	COG4670	ketone body catabolic process
E5O17_RS06855	COG2271	Major facilitator Superfamily
E5O17_RS06860	COG0738	Major facilitator superfamily
E5O17_RS06875	COG0628	permease
E5O17_RS06880	COG0247	lactate metabolic process
E5O17_RS06880	COG0277	FAD linked oxidase domain protein
E5O17_RS06885	COG2050	protein possibly involved in aromatic compounds catabolism
E5O17_RS06900	COG0316	Belongs to the HesB IscA family
E5O17_RS06905	COG0719	Fe-S assembly protein
E5O17_RS06910	COG0396	ATPase activity
E5O17_RS06915	COG0719	Fe-S assembly protein
E5O17_RS06930	COG1376	ErfK ybiS ycfS ynhG family protein
E5O17_RS06950	COG0531	amino acid
E5O17_RS06955	COG2267	carboxylic ester hydrolase activity
E5O17_RS06965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS07000	COG3272	Protein of unknown function (DUF1722)
E5O17_RS07005	COG0789	Transcriptional regulator
E5O17_RS07185	COG0307	riboflavin synthase, alpha
E5O17_RS07190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E5O17_RS07195	COG2814	Major facilitator Superfamily
E5O17_RS07200	COG0583	DNA-binding transcription factor activity
E5O17_RS07220	COG0791	NLP P60 protein
E5O17_RS07225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E5O17_RS07245	COG1902	pentaerythritol trinitrate reductase activity
E5O17_RS07250	COG1309	transcriptional regulator
E5O17_RS07255	COG3313	Fe-S protein
E5O17_RS07260	COG4989	oxidoreductase activity
E5O17_RS07275	COG1566	PFAM secretion protein HlyD family protein
E5O17_RS07300	COG3895	Periplasmic Protein
E5O17_RS07320	COG0625	glutathione transferase activity
E5O17_RS07330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E5O17_RS07380	COG0673	inositol 2-dehydrogenase activity
E5O17_RS07395	COG1263	PTS System
E5O17_RS07395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O17_RS07400	COG5339	Protein conserved in bacteria
E5O17_RS07425	COG2205	protein histidine kinase activity
E5O17_RS07430	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
E5O17_RS07435	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E5O17_RS07445	COG0745	RESPONSE REGULATOR receiver
E5O17_RS07450	COG3136	membrane protein required for alginate biosynthesis
E5O17_RS07455	COG0531	amino acid
E5O17_RS07465	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E5O17_RS07470	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E5O17_RS07475	COG0628	permease
E5O17_RS07495	COG3591	Belongs to the peptidase S1B family
E5O17_RS07505	COG2814	Major facilitator Superfamily
E5O17_RS07510	COG0583	DNA-binding transcription factor activity
E5O17_RS07515	COG1940	carbohydrate kinase activity
E5O17_RS07520	COG1940	carbohydrate kinase activity
E5O17_RS07560	COG3302	dmso reductase anchor subunit
E5O17_RS07565	COG0437	4 iron, 4 sulfur cluster binding
E5O17_RS07570	COG0243	molybdopterin cofactor binding
E5O17_RS07575	COG0243	molybdopterin cofactor binding
E5O17_RS07590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5O17_RS07610	COG1063	alcohol dehydrogenase
E5O17_RS07615	COG0477	Major facilitator Superfamily
E5O17_RS07620	COG0477	Major facilitator Superfamily
E5O17_RS07625	COG0246	Mannitol dehydrogenase
E5O17_RS07635	COG1802	Transcriptional regulator
E5O17_RS07640	COG4221	oxidoreductase activity
E5O17_RS07655	COG3729	General stress protein
E5O17_RS07660	COG1546	Belongs to the CinA family
E5O17_RS07665	COG3111	PFAM Bacterial OB fold (BOF) protein
E5O17_RS07675	COG2814	Major facilitator Superfamily
E5O17_RS07715	COG0583	DNA-binding transcription factor activity
E5O17_RS07720	COG1012	belongs to the aldehyde dehydrogenase family
E5O17_RS07735	COG3781	membrane
E5O17_RS07760	COG1773	rubredoxin
E5O17_RS07785	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E5O17_RS07790	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5O17_RS07800	COG2186	Transcriptional regulator
E5O17_RS07805	COG1063	alcohol dehydrogenase
E5O17_RS07810	COG2271	Major facilitator Superfamily
E5O17_RS07835	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E5O17_RS07840	COG0251	oxidation-reduction process
E5O17_RS07890	COG1609	Transcriptional regulator
E5O17_RS07895	COG1757	Na H antiporter
E5O17_RS07900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E5O17_RS07915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E5O17_RS07930	COG1764	response to oxidative stress
E5O17_RS07950	COG1064	alcohol dehydrogenase
E5O17_RS07955	COG2864	formate dehydrogenase
E5O17_RS07960	COG0437	4 iron, 4 sulfur cluster binding
E5O17_RS08000	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E5O17_RS08005	COG1140	nitrate reductase beta subunit
E5O17_RS08010	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E5O17_RS08015	COG2181	nitrate reductase activity
E5O17_RS08055	COG4772	TonB-dependent receptor
E5O17_RS08060	COG1802	Transcriptional regulator
E5O17_RS08065	COG2130	NADP-dependent
E5O17_RS08075	COG3238	Protein conserved in bacteria
E5O17_RS08115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5O17_RS08120	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E5O17_RS08145	COG0826	peptidase U32
E5O17_RS08150	COG1396	sequence-specific DNA binding
E5O17_RS08155	COG3135	benzoate transporter
E5O17_RS08165	COG0500	methyltransferase
E5O17_RS08170	COG1275	C4-dicarboxylate transporter malic acid transport protein
E5O17_RS08175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E5O17_RS08180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5O17_RS08190	COG3414	Phosphotransferase system galactitol-specific IIB component
E5O17_RS08195	COG3775	system Galactitol-specific IIC component
E5O17_RS08200	COG0434	BtpA family
E5O17_RS08205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS08210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E5O17_RS08215	COG1349	DNA-binding transcription factor activity
E5O17_RS08225	COG1304	FMN binding
E5O17_RS08230	COG2353	YceI-like domain
E5O17_RS08240	COG2272	Belongs to the type-B carboxylesterase lipase family
E5O17_RS08245	COG5383	Protein conserved in bacteria
E5O17_RS08250	COG0583	DNA-binding transcription factor activity
E5O17_RS08255	COG0840	transmembrane signaling receptor activity
E5O17_RS08290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O17_RS08295	COG0765	amino acid transport
E5O17_RS08305	COG0765	amino acid transport
E5O17_RS08315	COG0500	methyltransferase
E5O17_RS08320	COG3038	cytochrome b561
E5O17_RS08325	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E5O17_RS08330	COG1643	Atp-dependent helicase
E5O17_RS08345	COG3784	Protein of unknown function (DUF1318)
E5O17_RS08355	COG2911	Protein conserved in bacteria
E5O17_RS08360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E5O17_RS08365	COG3187	Heat shock protein
E5O17_RS08370	COG3042	response to heat
E5O17_RS08380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5O17_RS08380	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E5O17_RS08380	COG1013	pyruvate-flavodoxin oxidoreductase activity
E5O17_RS08380	COG0674	pyruvate-flavodoxin oxidoreductase activity
E5O17_RS08390	COG2076	Multidrug Resistance protein
E5O17_RS08410	COG0513	Belongs to the DEAD box helicase family
E5O17_RS08425	COG0840	transmembrane signaling receptor activity
E5O17_RS08430	COG2840	Smr protein MutS2
E5O17_RS08450	COG3182	Iron-regulated membrane protein
E5O17_RS08455	COG0668	transmembrane transport
E5O17_RS08475	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E5O17_RS08510	COG1309	transcriptional regulator
E5O17_RS08515	COG1028	Short-chain dehydrogenase reductase Sdr
E5O17_RS08520	COG0656	L-ascorbic acid biosynthetic process
E5O17_RS08525	COG0583	DNA-binding transcription factor activity
E5O17_RS08535	COG4166	transmembrane transport
E5O17_RS08540	COG2866	Carboxypeptidase
E5O17_RS08545	COG4948	Mandelate Racemase Muconate Lactonizing
E5O17_RS08565	COG3106	COG3106 Predicted ATPase
E5O17_RS08570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5O17_RS08580	COG1983	PspC domain protein
E5O17_RS08590	COG1842	Phage shock protein A
E5O17_RS08595	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E5O17_RS08650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5O17_RS08650	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5O17_RS08660	COG5001	Diguanylate cyclase
E5O17_RS08670	COG1349	DNA-binding transcription factor activity
E5O17_RS08690	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E5O17_RS08695	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E5O17_RS08700	COG0671	phosphoesterase, PA-phosphatase related
E5O17_RS08740	COG0616	signal peptide processing
E5O17_RS08745	COG1028	Short-chain dehydrogenase reductase Sdr
E5O17_RS08760	COG0009	L-threonylcarbamoyladenylate synthase
E5O17_RS08800	COG3729	General stress protein
E5O17_RS08805	COG3685	Protein conserved in bacteria
E5O17_RS08810	COG3685	Protein conserved in bacteria
E5O17_RS08815	COG3546	catalase activity
E5O17_RS08825	COG0727	PFAM Uncharacterised protein family (UPF0153)
E5O17_RS08850	COG2350	Protein conserved in bacteria
E5O17_RS08870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E5O17_RS08900	COG2095	MarC family integral membrane protein
E5O17_RS08905	COG1454	alcohol dehydrogenase
E5O17_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
E5O17_RS08920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E5O17_RS08925	COG0745	RESPONSE REGULATOR receiver
E5O17_RS08930	COG1752	Esterase of the alpha-beta hydrolase superfamily
E5O17_RS08940	COG0788	formyltetrahydrofolate deformylase activity
E5O17_RS08985	COG2181	nitrate reductase activity
E5O17_RS08990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E5O17_RS08995	COG1140	nitrate reductase beta subunit
E5O17_RS09000	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E5O17_RS09005	COG2223	nitrite transmembrane transporter activity
E5O17_RS09010	COG3850	Histidine kinase
E5O17_RS09015	COG2197	response regulator
E5O17_RS09020	COG4932	domain protein
E5O17_RS09025	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E5O17_RS09030	COG4572	Cation transport regulator
E5O17_RS09035	COG0387	Pfam Sodium calcium exchanger
E5O17_RS09085	COG0659	secondary active sulfate transmembrane transporter activity
E5O17_RS09100	COG0012	GTP binding
E5O17_RS09110	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5O17_RS09120	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E5O17_RS09125	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5O17_RS09130	COG1999	signal sequence binding
E5O17_RS09135	COG1773	rubredoxin
E5O17_RS09140	COG1271	oxidase subunit
E5O17_RS09145	COG1294	oxidase, subunit
E5O17_RS09155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E5O17_RS09180	COG1619	proteins homologs of microcin C7 resistance protein MccF
E5O17_RS09200	COG2719	SpoVR family
E5O17_RS09240	COG0179	Fumarylacetoacetate (FAA) hydrolase
E5O17_RS09255	COG2894	cell division
E5O17_RS09265	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E5O17_RS09275	COG3065	identical protein binding
E5O17_RS09285	COG1199	ATP-dependent helicase activity
E5O17_RS09290	COG0251	oxidation-reduction process
E5O17_RS09310	COG1760	l-serine dehydratase
E5O17_RS09315	COG2200	EAL domain
E5O17_RS09320	COG1253	flavin adenine dinucleotide binding
E5O17_RS09325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O17_RS09325	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS09330	COG3715	PTS system
E5O17_RS09335	COG3716	PTS system mannose fructose sorbose family IID component
E5O17_RS09350	COG2226	methyltransferase
E5O17_RS09355	COG0768	penicillin binding
E5O17_RS09385	COG1414	Transcriptional regulator
E5O17_RS09390	COG2814	Major facilitator Superfamily
E5O17_RS09410	COG1956	GAF domain-containing protein
E5O17_RS09415	COG2995	paraquat-inducible protein a
E5O17_RS09420	COG3008	intermembrane lipid transfer
E5O17_RS09455	COG5562	phage envelope protein
E5O17_RS09465	COG0454	-acetyltransferase
E5O17_RS09570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O17_RS09585	COG1276	copper resistance
E5O17_RS09590	COG2372	response to copper ion
E5O17_RS09600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5O17_RS09605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O17_RS09610	COG1770	oligopeptidase
E5O17_RS09615	COG2979	Protein of unknown function (DUF533)
E5O17_RS09625	COG3141	response to X-ray
E5O17_RS09635	COG0800	Aldolase
E5O17_RS09640	COG0129	dihydroxy-acid dehydratase activity
E5O17_RS09645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E5O17_RS09650	COG1737	Transcriptional regulator
E5O17_RS09660	COG1560	Kdo2-lipid A biosynthetic process
E5O17_RS09665	COG0739	heme binding
E5O17_RS09670	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E5O17_RS09680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5O17_RS09715	COG0494	nUDIX hydrolase
E5O17_RS09725	COG1335	isochorismatase
E5O17_RS09730	COG1801	Protein of unknown function DUF72
E5O17_RS09735	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E5O17_RS09755	COG3102	Protein conserved in bacteria
E5O17_RS09770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E5O17_RS09875	COG1528	Iron-storage protein
E5O17_RS09890	COG1528	Iron-storage protein
E5O17_RS09900	COG0814	amino acid
E5O17_RS09905	COG3318	Belongs to the UPF0149 family
E5O17_RS09905	COG3012	SEC-C Motif Domain Protein
E5O17_RS09950	COG2197	response regulator
E5O17_RS09965	COG2197	response regulator
E5O17_RS10045	COG0425	Belongs to the sulfur carrier protein TusA family
E5O17_RS10150	COG5475	Uncharacterized small protein (DUF2158)
E5O17_RS10155	COG2354	Protein conserved in bacteria
E5O17_RS10160	COG0697	spore germination
E5O17_RS10165	COG3727	T/G mismatch-specific endonuclease activity
E5O17_RS10170	COG0270	DNA (cytosine-5-)-methyltransferase activity
E5O17_RS10175	COG1418	mRNA catabolic process
E5O17_RS10185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E5O17_RS10260	COG3778	Protein conserved in bacteria
E5O17_RS10265	COG3299	homolog of phage Mu protein gp47
E5O17_RS10310	COG4386	tail sheath protein
E5O17_RS10355	COG4695	Portal protein
E5O17_RS10365	COG1802	Transcriptional regulator
E5O17_RS10365	COG4626	Terminase
E5O17_RS10395	COG3179	chitinase
E5O17_RS10420	COG0484	heat shock protein binding
E5O17_RS10425	COG1403	HNH endonuclease
E5O17_RS10435	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E5O17_RS10440	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E5O17_RS10460	COG3646	Phage regulatory protein
E5O17_RS10500	COG5532	Uncharacterized conserved protein (DUF2303)
E5O17_RS10505	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E5O17_RS10555	COG0582	viral genome integration into host DNA
E5O17_RS10610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E5O17_RS10635	COG0534	Mate efflux family protein
E5O17_RS10800	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E5O17_RS10830	COG1012	belongs to the aldehyde dehydrogenase family
E5O17_RS10830	COG1454	alcohol dehydrogenase
E5O17_RS10835	COG4656	Part of a membrane complex involved in electron transport
E5O17_RS10870	COG1289	transmembrane transporter activity
E5O17_RS10910	COG2925	Exonuclease
E5O17_RS10915	COG0531	amino acid
E5O17_RS10925	COG0583	DNA-binding transcription factor activity
E5O17_RS10930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5O17_RS11090	COG2327	Polysaccharide pyruvyl transferase
E5O17_RS11095	COG2244	polysaccharide biosynthetic process
E5O17_RS11100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E5O17_RS11115	COG0297	glycogen (starch) synthase activity
E5O17_RS11125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5O17_RS11130	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E5O17_RS11135	COG0110	maltose O-acetyltransferase activity
E5O17_RS11140	COG1216	Glycosyl transferase, family 2
E5O17_RS11150	COG0438	transferase activity, transferring glycosyl groups
E5O17_RS11155	COG1045	serine acetyltransferase
E5O17_RS11160	COG0463	Glycosyl transferase, family 2
E5O17_RS11180	COG1253	flavin adenine dinucleotide binding
E5O17_RS11185	COG2982	Protein involved in outer membrane biogenesis
E5O17_RS11200	COG3447	MASE1 domain protein
E5O17_RS11200	COG5001	Diguanylate cyclase
E5O17_RS11200	COG5002	protein histidine kinase activity
E5O17_RS11205	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E5O17_RS11210	COG0443	Heat shock 70 kDa protein
E5O17_RS11240	COG2205	protein histidine kinase activity
E5O17_RS11245	COG0745	RESPONSE REGULATOR receiver
E5O17_RS11290	COG1830	Aldolase
E5O17_RS11295	COG2211	Major facilitator Superfamily
E5O17_RS11300	COG1397	ADP-ribosylglycohydrolase
E5O17_RS11305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS11310	COG2188	Transcriptional regulator
E5O17_RS11325	COG5455	response to cobalt ion
E5O17_RS11330	COG3539	Fimbrial protein
E5O17_RS11335	COG3188	usher protein
E5O17_RS11340	COG3121	Chaperone
E5O17_RS11365	COG4808	Protein conserved in bacteria
E5O17_RS11375	COG4807	Protein conserved in bacteria
E5O17_RS11385	COG3275	phosphorelay sensor kinase activity
E5O17_RS11400	COG1174	glycine betaine transport
E5O17_RS11405	COG1125	glycine betaine transport
E5O17_RS11410	COG1174	glycine betaine transport
E5O17_RS11415	COG1732	Glycine betaine
E5O17_RS11425	COG0277	FAD linked oxidase domain protein
E5O17_RS11430	COG1686	Belongs to the peptidase S11 family
E5O17_RS11440	COG0586	Pfam SNARE associated Golgi protein
E5O17_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
E5O17_RS11450	COG1538	Outer membrane efflux protein
E5O17_RS11465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5O17_RS11470	COG0625	glutathione transferase activity
E5O17_RS11485	COG2271	Major facilitator Superfamily
E5O17_RS11500	COG1346	cytolysis
E5O17_RS11510	COG2949	membrane
E5O17_RS11550	COG2311	Membrane
E5O17_RS11570	COG1760	l-serine dehydratase
E5O17_RS11575	COG0560	Phosphoserine phosphatase
E5O17_RS11580	COG2271	Major facilitator Superfamily
E5O17_RS11585	COG4771	TonB-dependent receptor
E5O17_RS11590	COG0833	amino acid
E5O17_RS11595	COG0583	DNA-binding transcription factor activity
E5O17_RS11600	COG2855	membrane
E5O17_RS11610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O17_RS11610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O17_RS11610	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E5O17_RS11615	COG1105	Belongs to the carbohydrate kinase PfkB family
E5O17_RS11650	COG0523	cobalamin synthesis protein
E5O17_RS11655	COG0671	phosphoesterase, PA-phosphatase related
E5O17_RS11660	COG0791	NLP P60 protein
E5O17_RS11665	COG2200	EAL domain
E5O17_RS11670	COG4166	transmembrane transport
E5O17_RS11675	COG4174	ABC transporter (Permease)
E5O17_RS11680	COG4239	(ABC) transporter, permease
E5O17_RS11685	COG4172	Belongs to the ABC transporter superfamily
E5O17_RS11695	COG2814	Major facilitator Superfamily
E5O17_RS11705	COG1061	Type III restriction enzyme res subunit
E5O17_RS11800	COG1403	HNH endonuclease
E5O17_RS11820	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O17_RS11835	COG2197	response regulator
E5O17_RS11840	COG3088	subunit of a heme lyase
E5O17_RS11840	COG4235	cytochrome complex assembly
E5O17_RS11850	COG1138	Cytochrome C-type biogenesis protein
E5O17_RS11860	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O17_RS11865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O17_RS11870	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O17_RS11875	COG4133	protoheme IX ABC transporter activity
E5O17_RS11880	COG3005	denitrification pathway
E5O17_RS11885	COG3043	anaerobic respiration
E5O17_RS11890	COG0348	domain, Protein
E5O17_RS11895	COG0437	4 iron, 4 sulfur cluster binding
E5O17_RS11905	COG3062	negative regulation of establishment of protein localization
E5O17_RS11910	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O17_RS11910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O17_RS11920	COG4615	Cyclic peptide transporter
E5O17_RS11945	COG0642	Histidine kinase
E5O17_RS11945	COG2198	Histidine kinase
E5O17_RS11965	COG4948	Mandelate Racemase Muconate Lactonizing
E5O17_RS11995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5O17_RS12000	COG2814	Major facilitator Superfamily
E5O17_RS12005	COG0583	DNA-binding transcription factor activity
E5O17_RS12010	COG0584	glycerophosphoryl diester phosphodiesterase
E5O17_RS12015	COG2271	Major facilitator Superfamily
E5O17_RS12020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E5O17_RS12030	COG0247	lactate metabolic process
E5O17_RS12050	COG2271	Major facilitator Superfamily
E5O17_RS12060	COG1414	Transcriptional regulator
E5O17_RS12150	COG1169	isochorismate synthase
E5O17_RS12155	COG4575	ribosome binding
E5O17_RS12160	COG2153	protein acetylation
E5O17_RS12170	COG0835	chemotaxis
E5O17_RS12170	COG0784	Response regulator, receiver
E5O17_RS12175	COG2304	oxidoreductase activity
E5O17_RS12190	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5O17_RS12195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E5O17_RS12205	COG0839	Belongs to the complex I subunit 6 family
E5O17_RS12255	COG0583	DNA-binding transcription factor activity
E5O17_RS12260	COG0436	Aminotransferase
E5O17_RS12275	COG0471	metal ion transport
E5O17_RS12275	COG0490	domain, Protein
E5O17_RS12280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5O17_RS12305	COG1288	antiporter activity
E5O17_RS12310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E5O17_RS12315	COG3959	Transketolase, thiamine diphosphate binding domain
E5O17_RS12320	COG3037	sugar-specific permease SgaT UlaA
E5O17_RS12330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS12335	COG1609	Transcriptional regulator
E5O17_RS12345	COG0622	Phosphoesterase
E5O17_RS12350	COG0625	glutathione transferase activity
E5O17_RS12355	COG0625	glutathione transferase activity
E5O17_RS12360	COG1090	epimerase
E5O17_RS12395	COG0833	amino acid
E5O17_RS12400	COG3457	Alanine racemase
E5O17_RS12405	COG0531	amino acid
E5O17_RS12415	COG3829	transcription factor binding
E5O17_RS12420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E5O17_RS12425	COG1286	toxin biosynthetic process
E5O17_RS12430	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E5O17_RS12435	COG0285	dihydrofolate synthase activity
E5O17_RS12445	COG0586	Pfam SNARE associated Golgi protein
E5O17_RS12455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E5O17_RS12480	COG3423	Transcriptional regulator
E5O17_RS12505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5O17_RS12520	COG3101	peptidyl-lysine hydroxylation
E5O17_RS12525	COG0730	response to heat
E5O17_RS12550	COG2062	phosphohistidine phosphatase, SixA
E5O17_RS12565	COG3691	Protein conserved in bacteria
E5O17_RS12580	COG2116	formate transmembrane transporter activity
E5O17_RS12620	COG1560	Kdo2-lipid A biosynthetic process
E5O17_RS12630	COG0436	Aminotransferase
E5O17_RS12645	COG3961	Belongs to the TPP enzyme family
E5O17_RS12650	COG0667	Aldo Keto reductase
E5O17_RS12665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E5O17_RS12670	COG2199	diguanylate cyclase activity
E5O17_RS12670	COG2200	EAL domain
E5O17_RS12685	COG3415	Transposase
E5O17_RS12690	COG3415	Transposase
E5O17_RS12720	COG0583	DNA-binding transcription factor activity
E5O17_RS12730	COG2211	Major facilitator Superfamily
E5O17_RS12735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E5O17_RS12745	COG0583	DNA-binding transcription factor activity
E5O17_RS12750	COG0385	Bile acid
E5O17_RS12755	COG3530	Putative quorum-sensing-regulated virulence factor
E5O17_RS12780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS12835	COG4208	sulfate ABC transporter
E5O17_RS12860	COG2837	iron assimilation
E5O17_RS12995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E5O17_RS13005	COG5342	invasion associated locus B
E5O17_RS13020	COG0493	'glutamate synthase
E5O17_RS13020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O17_RS13025	COG3850	Histidine kinase
E5O17_RS13030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5O17_RS13040	COG1393	Belongs to the ArsC family
E5O17_RS13060	COG2321	neutral zinc metallopeptidase
E5O17_RS13070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E5O17_RS13080	COG2716	regulation of RNA biosynthetic process
E5O17_RS13085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5O17_RS13090	COG1929	Belongs to the glycerate kinase type-1 family
E5O17_RS13095	COG0628	permease
E5O17_RS13105	COG1393	Belongs to the ArsC family
E5O17_RS13115	COG2233	PERMEase
E5O17_RS13135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E5O17_RS13150	COG2200	EAL domain
E5O17_RS13190	COG0517	IMP dehydrogenase activity
E5O17_RS13190	COG0516	GMP reductase activity
E5O17_RS13230	COG1645	bacterial-type flagellum-dependent swarming motility
E5O17_RS13245	COG2976	Protein conserved in bacteria
E5O17_RS13285	COG0437	4 iron, 4 sulfur cluster binding
E5O17_RS13290	COG0243	molybdopterin cofactor binding
E5O17_RS13295	COG4953	penicillin-binding protein 1C
E5O17_RS13300	COG2373	Large extracellular alpha-helical protein
E5O17_RS13305	COG2897	thiosulfate sulfurtransferase activity
E5O17_RS13325	COG2975	iron-sulfur cluster assembly
E5O17_RS13330	COG0633	Ferredoxin
E5O17_RS13350	COG0822	iron-sulfur transferase activity
E5O17_RS13395	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E5O17_RS13405	COG3711	transcriptional antiterminator
E5O17_RS13410	COG2814	Major facilitator Superfamily
E5O17_RS13420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5O17_RS13420	COG1017	nitric oxide dioxygenase activity
E5O17_RS13425	COG3710	Transcriptional regulator
E5O17_RS13430	COG0531	amino acid
E5O17_RS13440	COG3104	oligopeptide transport
E5O17_RS13445	COG0347	Belongs to the P(II) protein family
E5O17_RS13450	COG2204	response regulator
E5O17_RS13455	COG3170	Tfp pilus assembly protein FimV
E5O17_RS13460	COG2205	protein histidine kinase activity
E5O17_RS13485	COG0560	Phosphoserine phosphatase
E5O17_RS13490	COG1263	PTS System
E5O17_RS13490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O17_RS13500	COG1737	Transcriptional regulator
E5O17_RS13505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E5O17_RS13510	COG2223	nitrite transmembrane transporter activity
E5O17_RS13515	COG0583	DNA-binding transcription factor activity
E5O17_RS13520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O17_RS13590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E5O17_RS13610	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O17_RS13720	COG4220	transposase activity
E5O17_RS13830	COG1484	DNA-dependent DNA replication
E5O17_RS13865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O17_RS13890	COG3086	response to oxidative stress
E5O17_RS13930	COG0513	Belongs to the DEAD box helicase family
E5O17_RS13935	COG0583	DNA-binding transcription factor activity
E5O17_RS13955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5O17_RS13960	COG3118	belongs to the thioredoxin family
E5O17_RS13975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5O17_RS13980	COG5544	Lipoprotein
E5O17_RS13985	COG0477	Major facilitator Superfamily
E5O17_RS14015	COG0542	response to heat
E5O17_RS14030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5O17_RS14035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E5O17_RS14045	COG1605	Chorismate mutase
E5O17_RS14045	COG0077	Prephenate dehydratase
E5O17_RS14055	COG0287	Prephenate dehydrogenase
E5O17_RS14055	COG1605	Chorismate mutase
E5O17_RS14070	COG2199	diguanylate cyclase activity
E5O17_RS14095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E5O17_RS14100	COG4137	Cytochrome C assembly protein
E5O17_RS14105	COG4536	flavin adenine dinucleotide binding
E5O17_RS14125	COG0497	DNA recombination
E5O17_RS14140	COG2867	negative regulation of translational initiation
E5O17_RS14165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O17_RS14175	COG0582	viral genome integration into host DNA
E5O17_RS14180	COG0582	viral genome integration into host DNA
E5O17_RS14210	COG4133	protoheme IX ABC transporter activity
E5O17_RS14225	COG3423	Transcriptional regulator
E5O17_RS14245	COG0673	inositol 2-dehydrogenase activity
E5O17_RS14255	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E5O17_RS14260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E5O17_RS14270	COG1263	PTS System
E5O17_RS14270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O17_RS14270	COG2190	(PTS) system
E5O17_RS14370	COG0786	glutamate:sodium symporter activity
E5O17_RS14385	COG0640	Transcriptional regulator
E5O17_RS14445	COG3300	MHYT domain
E5O17_RS14445	COG5001	Diguanylate cyclase
E5O17_RS14525	COG2819	hydrolase of the alpha beta superfamily
E5O17_RS14545	COG2990	Protein conserved in bacteria
E5O17_RS14560	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E5O17_RS14565	COG0642	Histidine kinase
E5O17_RS14595	COG0579	oxidoreductase
E5O17_RS14600	COG1012	belongs to the aldehyde dehydrogenase family
E5O17_RS14605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E5O17_RS14610	COG1113	amino acid transport
E5O17_RS14615	COG1802	Transcriptional regulator
E5O17_RS14620	COG1652	LysM domain
E5O17_RS14630	COG0401	homolog of Blt101
E5O17_RS14635	COG0640	Transcriptional regulator
E5O17_RS14640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5O17_RS14670	COG4575	ribosome binding
E5O17_RS14680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5O17_RS14725	COG2814	Major facilitator Superfamily
E5O17_RS14730	COG1846	Transcriptional regulator
E5O17_RS14735	COG1566	PFAM secretion protein HlyD family protein
E5O17_RS14740	COG2814	Major facilitator Superfamily
E5O17_RS14760	COG1238	metal cluster binding
E5O17_RS14765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5O17_RS14795	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E5O17_RS14820	COG1546	Belongs to the CinA family
E5O17_RS14830	COG2951	lytic endotransglycosylase activity
E5O17_RS14835	COG3730	PTS system glucitol sorbitol-specific
E5O17_RS14840	COG3732	PTS system glucitol sorbitol-specific
E5O17_RS14850	COG1028	Short-chain dehydrogenase reductase Sdr
E5O17_RS14855	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS14860	COG1349	DNA-binding transcription factor activity
E5O17_RS14885	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E5O17_RS14890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O17_RS14900	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5O17_RS14910	COG3260	NADH ubiquinone oxidoreductase 20
E5O17_RS14915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5O17_RS14920	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E5O17_RS14920	COG3261	NADH dehydrogenase
E5O17_RS14925	COG0650	Formate hydrogenlyase subunit 4
E5O17_RS14930	COG0651	ATP synthesis coupled electron transport
E5O17_RS14935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O17_RS14950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E5O17_RS14955	COG0298	carbon dioxide binding
E5O17_RS14960	COG0409	Hydrogenase expression formation protein
E5O17_RS14965	COG0309	Hydrogenase expression formation protein (HypE)
E5O17_RS14985	COG1121	(ABC) transporter
E5O17_RS14990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5O17_RS14995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5O17_RS15170	COG2207	Transcriptional regulator
E5O17_RS15235	COG0477	Major facilitator Superfamily
E5O17_RS15245	COG2610	gluconate transmembrane transporter activity
E5O17_RS15250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5O17_RS15255	COG3622	Belongs to the hyi family
E5O17_RS15260	COG0235	Class ii aldolase
E5O17_RS15270	COG2084	Dehydrogenase
E5O17_RS15275	COG1349	DNA-binding transcription factor activity
E5O17_RS15285	COG0163	prenyltransferase activity
E5O17_RS15290	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E5O17_RS15360	COG2234	aminopeptidase activity
E5O17_RS15365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5O17_RS15370	COG1518	maintenance of DNA repeat elements
E5O17_RS15385	COG1857	crispr-associated protein
E5O17_RS15425	COG0720	synthase
E5O17_RS15430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E5O17_RS15430	COG0321	lipoyl(octanoyl) transferase activity
E5O17_RS15435	COG0602	queuosine metabolic process
E5O17_RS15450	COG3956	TIGRFAM MazG family protein
E5O17_RS15465	COG3609	addiction module antidote protein, CC2985 family
E5O17_RS15470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5O17_RS15480	COG3437	response regulator, receiver
E5O17_RS15480	COG4999	Histidine kinase
E5O17_RS15480	COG3850	Histidine kinase
E5O17_RS15480	COG2205	protein histidine kinase activity
E5O17_RS15485	COG1929	Belongs to the glycerate kinase type-1 family
E5O17_RS15490	COG4948	Mandelate Racemase Muconate Lactonizing
E5O17_RS15495	COG4948	Mandelate Racemase Muconate Lactonizing
E5O17_RS15500	COG2271	Major facilitator Superfamily
E5O17_RS15510	COG0716	FMN binding
E5O17_RS15520	COG3098	single-species biofilm formation
E5O17_RS15540	COG1611	Belongs to the LOG family
E5O17_RS15545	COG0814	amino acid
E5O17_RS15550	COG1760	l-serine dehydratase
E5O17_RS15560	COG1454	alcohol dehydrogenase
E5O17_RS15565	COG0235	Class ii aldolase
E5O17_RS15570	COG0738	Major facilitator superfamily
E5O17_RS15590	COG1349	DNA-binding transcription factor activity
E5O17_RS15600	COG2363	Small membrane protein
E5O17_RS15605	COG0583	DNA-binding transcription factor activity
E5O17_RS15615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E5O17_RS15620	COG2166	iron-sulfur cluster assembly
E5O17_RS15625	COG2962	Rard protein
E5O17_RS15630	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E5O17_RS15635	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E5O17_RS15650	COG0860	N-Acetylmuramoyl-L-alanine amidase
E5O17_RS15660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E5O17_RS15665	COG1074	ATP-dependent DNA helicase activity
E5O17_RS15675	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E5O17_RS15680	COG4967	type IV pilus modification protein PilV
E5O17_RS15690	COG4795	General secretion pathway protein
E5O17_RS15695	COG2165	general secretion pathway protein
E5O17_RS15725	COG0861	Integral membrane protein TerC family
E5O17_RS15735	COG0667	Aldo Keto reductase
E5O17_RS15755	COG1609	Transcriptional regulator
E5O17_RS15765	COG0583	DNA-binding transcription factor activity
E5O17_RS15770	COG1794	racemase activity, acting on amino acids and derivatives
E5O17_RS15775	COG2814	Major facilitator Superfamily
E5O17_RS15780	COG1028	Short-chain dehydrogenase reductase Sdr
E5O17_RS15790	COG0183	Belongs to the thiolase family
E5O17_RS15805	COG0814	amino acid
E5O17_RS15840	COG3188	usher protein
E5O17_RS15890	COG4942	peptidase
E5O17_RS15945	COG1272	protein, Hemolysin III
E5O17_RS15955	COG2723	6-phospho-beta-galactosidase activity
E5O17_RS15985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5O17_RS15990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5O17_RS15995	COG0006	proline dipeptidase activity
E5O17_RS16015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E5O17_RS16020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E5O17_RS16035	COG2968	Membrane
E5O17_RS16045	COG0668	transmembrane transport
E5O17_RS16050	COG0191	fructose-bisphosphate aldolase activity
E5O17_RS16080	COG1122	ATPase activity
E5O17_RS16085	COG1122	ATPase activity
E5O17_RS16090	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E5O17_RS16095	COG0501	Belongs to the peptidase M48B family
E5O17_RS16105	COG2267	carboxylic ester hydrolase activity
E5O17_RS16110	COG2731	YhcH YjgK YiaL family protein
E5O17_RS16115	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E5O17_RS16120	COG1063	alcohol dehydrogenase
E5O17_RS16125	COG0246	Mannitol dehydrogenase
E5O17_RS16135	COG2186	Transcriptional regulator
E5O17_RS16145	COG1166	arginine decarboxylase activity
E5O17_RS16165	COG2814	Major facilitator Superfamily
E5O17_RS16175	COG2356	endonuclease I
E5O17_RS16180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E5O17_RS16205	COG2805	Type II/IV secretion system protein
E5O17_RS16210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E5O17_RS16215	COG0762	integral membrane protein
E5O17_RS16230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E5O17_RS16240	COG0252	asparaginase activity
E5O17_RS16250	COG3171	Protein conserved in bacteria
E5O17_RS16275	COG2211	Major facilitator Superfamily
E5O17_RS16280	COG1982	Orn Lys Arg decarboxylase major
E5O17_RS16285	COG1811	Na channel or pump
E5O17_RS16300	COG0427	acetyl-CoA hydrolase
E5O17_RS16305	COG2030	dehydratase
E5O17_RS16310	COG2301	Belongs to the HpcH HpaI aldolase family
E5O17_RS16340	COG0531	amino acid
E5O17_RS16350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E5O17_RS16355	COG1012	belongs to the aldehyde dehydrogenase family
E5O17_RS16380	COG2271	Major facilitator Superfamily
E5O17_RS16390	COG0246	Mannitol dehydrogenase
E5O17_RS16405	COG0754	glutathionylspermidine amidase activity
E5O17_RS16410	COG0625	glutathione transferase activity
E5O17_RS16425	COG0298	carbon dioxide binding
E5O17_RS16435	COG1773	rubredoxin
E5O17_RS16440	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5O17_RS16445	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E5O17_RS16450	COG5557	Pfam Polysulphide reductase, NrfD
E5O17_RS16455	COG0437	4 iron, 4 sulfur cluster binding
E5O17_RS16460	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5O17_RS16470	COG0840	transmembrane signaling receptor activity
E5O17_RS16495	COG1028	Short-chain dehydrogenase reductase Sdr
E5O17_RS16500	COG0848	biopolymer transport protein
E5O17_RS16520	COG2207	Transcriptional regulator
E5O17_RS16525	COG1979	alcohol dehydrogenase
E5O17_RS16535	COG0471	metal ion transport
E5O17_RS16590	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5O17_RS16595	COG3111	PFAM Bacterial OB fold (BOF) protein
E5O17_RS16610	COG2249	NAD(P)H dehydrogenase (quinone) activity
E5O17_RS16615	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E5O17_RS16625	COG3150	esterase
E5O17_RS16630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E5O17_RS16635	COG3151	Protein conserved in bacteria
E5O17_RS16640	COG0494	nUDIX hydrolase
E5O17_RS16655	COG0754	glutathionylspermidine amidase activity
E5O17_RS16660	COG3384	dioxygenase
E5O17_RS16700	COG1585	Membrane protein implicated in regulation of membrane protease activity
E5O17_RS16705	COG2268	Band 7 protein
E5O17_RS16725	COG3025	triphosphatase activity
E5O17_RS16730	COG4991	sh3 domain protein
E5O17_RS16745	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E5O17_RS16765	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E5O17_RS16820	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O17_RS16915	COG4695	Portal protein
E5O17_RS16980	COG4974	Belongs to the 'phage' integrase family
E5O17_RS16990	COG2375	cellular response to nickel ion
E5O17_RS16995	COG1695	Transcriptional regulator
E5O17_RS17000	COG0840	transmembrane signaling receptor activity
E5O17_RS17005	COG0840	transmembrane signaling receptor activity
E5O17_RS17015	COG0446	pyridine nucleotide-disulphide oxidoreductase
E5O17_RS17015	COG1902	pentaerythritol trinitrate reductase activity
E5O17_RS17025	COG1451	nucleotide metabolic process
E5O17_RS17030	COG2949	membrane
E5O17_RS17035	COG0673	inositol 2-dehydrogenase activity
E5O17_RS17050	COG0586	Pfam SNARE associated Golgi protein
E5O17_RS17060	COG1422	Protein of unknown function (DUF1090)
E5O17_RS17065	COG4575	ribosome binding
E5O17_RS17070	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E5O17_RS17080	COG2259	Doxx family
E5O17_RS17085	COG0435	Glutathione S-transferase
E5O17_RS17090	COG3152	Membrane
E5O17_RS17095	COG0583	DNA-binding transcription factor activity
E5O17_RS17100	COG1741	Belongs to the pirin family
E5O17_RS17115	COG0814	amino acid
E5O17_RS17120	COG1760	l-serine dehydratase
E5O17_RS17125	COG1882	Formate acetyltransferase
E5O17_RS17145	COG0583	DNA-binding transcription factor activity
E5O17_RS17155	COG1929	Belongs to the glycerate kinase type-1 family
E5O17_RS17160	COG2084	Dehydrogenase
E5O17_RS17170	COG2721	sulfolactate sulfo-lyase activity
E5O17_RS17175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS17180	COG1349	DNA-binding transcription factor activity
E5O17_RS17190	COG1105	Belongs to the carbohydrate kinase PfkB family
E5O17_RS17195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS17195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O17_RS17195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O17_RS17210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS17215	COG3414	Phosphotransferase system galactitol-specific IIB component
E5O17_RS17220	COG3775	system Galactitol-specific IIC component
E5O17_RS17225	COG1063	alcohol dehydrogenase
E5O17_RS17235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E5O17_RS17255	COG2823	Periplasmic or secreted lipoprotein
E5O17_RS17260	COG0702	epimerase
E5O17_RS17265	COG0693	protein deglycase activity
E5O17_RS17280	COG3153	acetyltransferase
E5O17_RS17285	COG3154	lipid carrier protein
E5O17_RS17290	COG0826	peptidase U32
E5O17_RS17295	COG0826	peptidase U32
E5O17_RS17300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E5O17_RS17305	COG3034	peptidoglycan biosynthetic process
E5O17_RS17315	COG0814	amino acid
E5O17_RS17320	COG0513	Belongs to the DEAD box helicase family
E5O17_RS17390	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E5O17_RS17400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E5O17_RS17415	COG1534	Rna-binding protein
E5O17_RS17425	COG2027	D-alanyl-D-alanine carboxypeptidase
E5O17_RS17435	COG0697	spore germination
E5O17_RS17450	COG0142	geranyltranstransferase activity
E5O17_RS17455	COG3423	Transcriptional regulator
E5O17_RS17465	COG5007	Belongs to the BolA IbaG family
E5O17_RS17470	COG3113	response to antibiotic
E5O17_RS17475	COG2854	intermembrane phospholipid transfer
E5O17_RS17480	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E5O17_RS17485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E5O17_RS17490	COG1127	ABC transporter
E5O17_RS17495	COG0530	calcium, potassium:sodium antiporter activity
E5O17_RS17510	COG3117	lipopolysaccharide transmembrane transporter activity
E5O17_RS17515	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E5O17_RS17520	COG1137	ATPase activity
E5O17_RS17545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS17550	COG0515	serine threonine protein kinase
E5O17_RS17560	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E5O17_RS17565	COG2198	Histidine kinase
E5O17_RS17565	COG5002	protein histidine kinase activity
E5O17_RS17565	COG0784	Response regulator, receiver
E5O17_RS17570	COG1242	4 iron, 4 sulfur cluster binding
E5O17_RS17575	COG0070	glutamate synthase
E5O17_RS17575	COG0069	glutamate synthase activity
E5O17_RS17575	COG0067	glutamate synthase
E5O17_RS17580	COG0493	'glutamate synthase
E5O17_RS17585	COG4804	nuclease activity
E5O17_RS17590	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E5O17_RS17595	COG0402	S-adenosylhomocysteine deaminase activity
E5O17_RS17600	COG2731	YhcH YjgK YiaL family protein
E5O17_RS17630	COG2969	positive regulation of protein catabolic process
E5O17_RS17635	COG0625	glutathione transferase activity
E5O17_RS17660	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E5O17_RS17665	COG3105	Protein conserved in bacteria
E5O17_RS17670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E5O17_RS17680	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
E5O17_RS17700	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O17_RS17705	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O17_RS17710	COG0471	metal ion transport
E5O17_RS17720	COG2188	Transcriptional regulator
E5O17_RS17745	COG2732	(Barnase) inhibitor
E5O17_RS17765	COG0583	DNA-binding transcription factor activity
E5O17_RS17770	COG0312	modulator of DNA gyrase
E5O17_RS17775	COG3164	Protein of unknown function
E5O17_RS17780	COG1530	ribonuclease E activity
E5O17_RS17790	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E5O17_RS17795	COG1792	Involved in formation and maintenance of cell shape
E5O17_RS17800	COG1077	Cell shape determining protein MreB Mrl
E5O17_RS17805	COG2200	EAL domain
E5O17_RS17805	COG2199	diguanylate cyclase activity
E5O17_RS17810	COG0604	alcohol dehydrogenase
E5O17_RS17830	COG0511	ligase activity, forming carbon-carbon bonds
E5O17_RS17835	COG0439	Biotin carboxylase
E5O17_RS17840	COG3924	membrane
E5O17_RS17845	COG4145	pantothenate transmembrane transporter activity
E5O17_RS17865	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E5O17_RS17880	COG1309	transcriptional regulator
E5O17_RS17885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O17_RS17890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5O17_RS17930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E5O17_RS17950	COG0551	DNA topoisomerase type I activity
E5O17_RS17960	COG0758	DNA mediated transformation
E5O17_RS17990	COG3036	rescue of stalled ribosome
E5O17_RS17995	COG0789	Transcriptional regulator
E5O17_RS18035	COG0201	protein transport
E5O17_RS18115	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E5O17_RS18140	COG0051	transcription antitermination factor activity, RNA binding
E5O17_RS18195	COG2964	Protein conserved in bacteria
E5O17_RS18205	COG0545	Peptidyl-prolyl cis-trans isomerase
E5O17_RS18215	COG1047	Peptidyl-prolyl cis-trans
E5O17_RS18220	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E5O17_RS18235	COG0488	(ABC) transporter
E5O17_RS18250	COG0429	hydrolase of the alpha beta-hydrolase fold
E5O17_RS18260	COG3954	Phosphoribulokinase
E5O17_RS18265	COG1765	OsmC-like protein
E5O17_RS18275	COG1289	transmembrane transporter activity
E5O17_RS18310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E5O17_RS18355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E5O17_RS18360	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E5O17_RS18365	COG3266	domain, Protein
E5O17_RS18380	COG4796	Type ii and iii secretion system protein
E5O17_RS18395	COG3166	PFAM Fimbrial assembly family protein
E5O17_RS18400	COG4972	Pilus assembly protein
E5O17_RS18405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E5O17_RS18410	COG0494	nUDIX hydrolase
E5O17_RS18420	COG1011	Hydrolase
E5O17_RS18425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E5O17_RS18435	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5O17_RS18450	COG0745	RESPONSE REGULATOR receiver
E5O17_RS18460	COG2183	response to ionizing radiation
E5O17_RS18465	COG1918	ferrous iron import across plasma membrane
E5O17_RS18480	COG5464	transposase or invertase
E5O17_RS18500	COG2610	gluconate transmembrane transporter activity
E5O17_RS18505	COG1640	4-alpha-glucanotransferase
E5O17_RS18510	COG0058	SHG alpha-glucan phosphorylase activity
E5O17_RS18520	COG3041	Addiction module toxin RelE StbE family
E5O17_RS18525	COG3077	Addiction module antitoxin, RelB DinJ family
E5O17_RS18535	COG1690	Belongs to the RtcB family
E5O17_RS18550	COG4650	regulator
E5O17_RS18555	COG1349	DNA-binding transcription factor activity
E5O17_RS18570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E5O17_RS18585	COG0371	Dehydrogenase
E5O17_RS18595	COG0129	dihydroxy-acid dehydratase activity
E5O17_RS18600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E5O17_RS18605	COG1414	Transcriptional regulator
E5O17_RS18610	COG0058	SHG alpha-glucan phosphorylase activity
E5O17_RS18640	COG2095	MarC family integral membrane protein
E5O17_RS18645	COG2610	gluconate transmembrane transporter activity
E5O17_RS18650	COG3265	gluconokinase activity
E5O17_RS18655	COG1609	Transcriptional regulator
E5O17_RS18660	COG1741	Belongs to the pirin family
E5O17_RS18665	COG0673	inositol 2-dehydrogenase activity
E5O17_RS18670	COG1247	-acetyltransferase
E5O17_RS18675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS18690	COG1735	metal-dependent hydrolase with the TIM-barrel fold
E5O17_RS18695	COG0405	Gamma-glutamyltransferase
E5O17_RS18705	COG0584	glycerophosphoryl diester phosphodiesterase
E5O17_RS18785	COG2177	Part of the ABC transporter FtsEX involved in
E5O17_RS18790	COG2884	Cell division ATP-binding protein ftsE
E5O17_RS18795	COG0552	protein localization to endoplasmic reticulum
E5O17_RS18800	COG0742	ribosomal rna small subunit methyltransferase
E5O17_RS18805	COG3776	membrane
E5O17_RS18815	COG3714	YhhN family
E5O17_RS18835	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E5O17_RS18850	COG0628	permease
E5O17_RS18865	COG0842	Transport permease protein
E5O17_RS18870	COG1129	ABC transporter
E5O17_RS18870	COG0842	Transport permease protein
E5O17_RS18875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O17_RS18880	COG2081	HI0933 family
E5O17_RS18885	COG0306	phosphate transporter
E5O17_RS18915	COG0671	phosphoesterase, PA-phosphatase related
E5O17_RS18920	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E5O17_RS18925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5O17_RS18935	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5O17_RS18940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS18945	COG2222	sugar isomerase
E5O17_RS18950	COG2188	Transcriptional regulator
E5O17_RS18970	COG2197	response regulator
E5O17_RS18975	COG0583	DNA-binding transcription factor activity
E5O17_RS18980	COG1295	ribonuclease BN
E5O17_RS18985	COG0477	Major facilitator Superfamily
E5O17_RS18990	COG2982	Protein involved in outer membrane biogenesis
E5O17_RS18995	COG2200	EAL domain
E5O17_RS19000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS19015	COG2200	EAL domain
E5O17_RS19015	COG2199	diguanylate cyclase activity
E5O17_RS19075	COG0814	amino acid
E5O17_RS19080	COG4608	Belongs to the ABC transporter superfamily
E5O17_RS19085	COG0444	Belongs to the ABC transporter superfamily
E5O17_RS19090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E5O17_RS19095	COG0601	transmembrane transport
E5O17_RS19100	COG0747	negative chemotaxis
E5O17_RS19160	COG5571	outer membrane autotransporter
E5O17_RS19165	COG2818	Glycosylase
E5O17_RS19170	COG0456	acetyltransferase
E5O17_RS19175	COG0243	molybdopterin cofactor binding
E5O17_RS19180	COG2885	chlorophyll binding
E5O17_RS19195	COG2944	sequence-specific DNA binding
E5O17_RS19200	COG1278	Cold shock
E5O17_RS19225	COG2801	Transposase and inactivated derivatives
E5O17_RS19250	COG3274	enterobacterial common antigen metabolic process
E5O17_RS19255	COG4682	membrane
E5O17_RS19260	COG1070	Carbohydrate kinase
E5O17_RS19270	COG1609	Transcriptional regulator
E5O17_RS19270	COG2207	Transcriptional regulator
E5O17_RS19275	COG2992	FlgJ-related protein
E5O17_RS19280	COG0366	Alpha amylase catalytic
E5O17_RS19285	COG3977	Valine--pyruvate aminotransferase
E5O17_RS19290	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5O17_RS19295	COG1414	Transcriptional regulator
E5O17_RS19305	COG2731	YhcH YjgK YiaL family protein
E5O17_RS19315	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E5O17_RS19320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E5O17_RS19325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E5O17_RS19330	COG1070	Carbohydrate kinase
E5O17_RS19335	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E5O17_RS19340	COG3623	hexulose-6-phosphate isomerase
E5O17_RS19345	COG0235	Class ii aldolase
E5O17_RS19360	COG1012	belongs to the aldehyde dehydrogenase family
E5O17_RS19365	COG1940	carbohydrate kinase activity
E5O17_RS19370	COG3276	selenocysteine insertion sequence binding
E5O17_RS19380	COG0625	glutathione transferase activity
E5O17_RS19385	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS19385	COG2213	PTS system mannitol-specific
E5O17_RS19395	COG3722	fumarate hydratase activity
E5O17_RS19425	COG2186	Transcriptional regulator
E5O17_RS19435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E5O17_RS19440	COG1609	Transcriptional regulator
E5O17_RS19450	COG2271	Major facilitator Superfamily
E5O17_RS19470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E5O17_RS19475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5O17_RS19485	COG4942	peptidase
E5O17_RS19490	COG2861	carbohydrate metabolic process
E5O17_RS19495	COG1216	Glycosyl transferase, family 2
E5O17_RS19575	COG0438	transferase activity, transferring glycosyl groups
E5O17_RS19580	COG0859	PFAM glycosyl transferase family 9
E5O17_RS19585	COG1519	Transferase
E5O17_RS19615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E5O17_RS19640	COG1561	YicC-like family, N-terminal region
E5O17_RS19645	COG0583	DNA-binding transcription factor activity
E5O17_RS19655	COG2860	membrane
E5O17_RS19675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5O17_RS19680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5O17_RS19685	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E5O17_RS19695	COG0786	glutamate:sodium symporter activity
E5O17_RS19700	COG2233	PERMEase
E5O17_RS19705	COG2982	Protein involved in outer membrane biogenesis
E5O17_RS19710	COG1501	Belongs to the glycosyl hydrolase 31 family
E5O17_RS19715	COG2211	Major facilitator Superfamily
E5O17_RS19735	COG0419	ATPase involved in DNA repair
E5O17_RS19760	COG2771	luxR family
E5O17_RS19775	COG3710	Transcriptional regulator
E5O17_RS19785	COG1335	isochorismatase
E5O17_RS19815	COG5464	transposase or invertase
E5O17_RS19830	COG3716	PTS system mannose fructose sorbose family IID component
E5O17_RS19835	COG3715	PTS system
E5O17_RS19840	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O17_RS19840	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS19860	COG2723	6-phospho-beta-galactosidase activity
E5O17_RS19895	COG3775	system Galactitol-specific IIC component
E5O17_RS19900	COG3414	Phosphotransferase system galactitol-specific IIB component
E5O17_RS19905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS19905	COG3711	transcriptional antiterminator
E5O17_RS19910	COG2188	Transcriptional regulator
E5O17_RS19945	COG0738	Major facilitator superfamily
E5O17_RS19955	COG1349	DNA-binding transcription factor activity
E5O17_RS19960	COG0440	acetolactate synthase activity
E5O17_RS19965	COG0028	Belongs to the TPP enzyme family
E5O17_RS19990	COG2814	Major facilitator Superfamily
E5O17_RS20000	COG0583	DNA-binding transcription factor activity
E5O17_RS20005	COG2610	gluconate transmembrane transporter activity
E5O17_RS20015	COG0641	radical SAM
E5O17_RS20025	COG2149	membrane
E5O17_RS20045	COG5645	(Lipo)protein
E5O17_RS20050	COG0823	Involved in the tonB-independent uptake of proteins
E5O17_RS20075	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5O17_RS20095	COG1858	cytochrome C peroxidase
E5O17_RS20110	COG3005	denitrification pathway
E5O17_RS20115	COG0745	RESPONSE REGULATOR receiver
E5O17_RS20120	COG1879	ABC-type sugar transport system periplasmic component
E5O17_RS20125	COG0784	Response regulator, receiver
E5O17_RS20125	COG2198	Histidine kinase
E5O17_RS20125	COG2205	protein histidine kinase activity
E5O17_RS20130	COG2271	Major facilitator Superfamily
E5O17_RS20140	COG0800	Aldolase
E5O17_RS20145	COG3734	2-keto-3-deoxy-galactonokinase
E5O17_RS20150	COG2186	Transcriptional regulator
E5O17_RS20155	COG0561	phosphatase activity
E5O17_RS20160	COG2271	Major facilitator Superfamily
E5O17_RS20165	COG4948	Mandelate Racemase Muconate Lactonizing
E5O17_RS20245	COG2091	lysine biosynthetic process via aminoadipic acid
E5O17_RS20250	COG0431	NADPH-dependent FMN reductase
E5O17_RS20255	COG2252	PERMEase
E5O17_RS20260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5O17_RS20265	COG0704	Plays a role in the regulation of phosphate uptake
E5O17_RS20275	COG0581	inorganic phosphate transmembrane transporter activity
E5O17_RS20280	COG0573	inorganic phosphate transmembrane transporter activity
E5O17_RS20285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E5O17_RS20290	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E5O17_RS20290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O17_RS20290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O17_RS20295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E5O17_RS20300	COG4533	DNA binding
E5O17_RS20360	COG3312	ion transport
E5O17_RS20375	COG0716	FMN binding
E5O17_RS20380	COG1522	sequence-specific DNA binding
E5O17_RS20415	COG1172	Belongs to the binding-protein-dependent transport system permease family
E5O17_RS20425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS20430	COG1609	Transcriptional regulator
E5O17_RS20435	COG0477	Major facilitator Superfamily
E5O17_RS20440	COG2186	Transcriptional regulator
E5O17_RS20500	COG3978	acetolactate synthase activity
E5O17_RS20550	COG3201	nicotinamide mononucleotide transporter
E5O17_RS20570	COG3118	belongs to the thioredoxin family
E5O17_RS20605	COG1088	dTDP-glucose 4,6-dehydratase activity
E5O17_RS20610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E5O17_RS20610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E5O17_RS20615	COG0456	acetyltransferase
E5O17_RS20620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E5O17_RS20625	COG2244	polysaccharide biosynthetic process
E5O17_RS20670	COG3071	HemY protein
E5O17_RS20675	COG2959	enzyme of heme biosynthesis
E5O17_RS20745	COG1011	Hydrolase
E5O17_RS20800	COG2267	carboxylic ester hydrolase activity
E5O17_RS20805	COG0561	phosphatase activity
E5O17_RS20830	COG0641	radical SAM
E5O17_RS20875	COG0805	protein transport
E5O17_RS20920	COG1739	Uncharacterized protein family UPF0029
E5O17_RS20960	COG1763	Mo-molybdopterin cofactor biosynthetic process
E5O17_RS20970	COG3084	Protein conserved in bacteria
E5O17_RS20985	COG0204	Acyl-transferase
E5O17_RS21040	COG0561	phosphatase activity
E5O17_RS21085	COG1501	Belongs to the glycosyl hydrolase 31 family
E5O17_RS21090	COG2017	converts alpha-aldose to the beta-anomer
E5O17_RS21110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS21115	COG1349	DNA-binding transcription factor activity
E5O17_RS21120	COG1011	Hydrolase
E5O17_RS21135	COG0456	acetyltransferase
E5O17_RS21140	COG5499	transcription regulator containing HTH domain
E5O17_RS21145	COG4680	protein conserved in bacteria
E5O17_RS21155	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
E5O17_RS21170	COG2864	formate dehydrogenase
E5O17_RS21175	COG0437	4 iron, 4 sulfur cluster binding
E5O17_RS21205	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E5O17_RS21220	COG1454	alcohol dehydrogenase
E5O17_RS21265	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E5O17_RS21280	COG2258	MOSC domain
E5O17_RS21290	COG2205	protein histidine kinase activity
E5O17_RS21295	COG0745	RESPONSE REGULATOR receiver
E5O17_RS21300	COG3678	ATP-independent chaperone mediated protein folding
E5O17_RS21325	COG2211	Major facilitator Superfamily
E5O17_RS21340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5O17_RS21350	COG2134	cdp-diacylglycerol pyrophosphatase
E5O17_RS21360	COG1070	Carbohydrate kinase
E5O17_RS21415	COG3152	Membrane
E5O17_RS21425	COG1494	fructose-1,6-bisphosphatase
E5O17_RS21435	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E5O17_RS21450	COG1575	Belongs to the MenA family. Type 1 subfamily
E5O17_RS21465	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E5O17_RS21470	COG1609	Transcriptional regulator
E5O17_RS21475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E5O17_RS21500	COG0626	cystathionine gamma-synthase activity
E5O17_RS21505	COG0527	aspartate kinase activity
E5O17_RS21505	COG0460	homoserine dehydrogenase
E5O17_RS21510	COG0668	transmembrane transport
E5O17_RS21525	COG0737	Belongs to the 5'-nucleotidase family
E5O17_RS21540	COG3738	Protein conserved in bacteria
E5O17_RS21545	COG0371	Dehydrogenase
E5O17_RS21555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS21555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS21555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5O17_RS21560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O17_RS21565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O17_RS21570	COG1882	Formate acetyltransferase
E5O17_RS21575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5O17_RS21580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5O17_RS21585	COG2207	Transcriptional regulator
E5O17_RS21620	COG0583	DNA-binding transcription factor activity
E5O17_RS21730	COG0250	Participates in transcription elongation, termination and antitermination
E5O17_RS21800	COG2104	thiamine diphosphate biosynthetic process
E5O17_RS21805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E5O17_RS21915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E5O17_RS21960	COG3122	Protein conserved in bacteria
E5O17_RS22000	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5O17_RS22030	COG2246	polysaccharide biosynthetic process
E5O17_RS22110	COG0527	aspartate kinase activity
E5O17_RS22135	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5O17_RS22195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E5O17_RS22205	COG0534	Mate efflux family protein
E5O17_RS22220	COG0735	belongs to the Fur family
E5O17_RS22260	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E5O17_RS22265	COG5532	Uncharacterized conserved protein (DUF2303)
E5O17_RS22295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E5O17_RS22300	COG4197	protein conserved in bacteria, prophage-related
E5O17_RS22315	COG1846	Transcriptional regulator
E5O17_RS22325	COG4725	Belongs to the MT-A70-like family
E5O17_RS22335	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E5O17_RS22345	COG1403	HNH endonuclease
E5O17_RS22350	COG0484	heat shock protein binding
E5O17_RS22375	COG3179	chitinase
E5O17_RS22405	COG4626	Terminase
E5O17_RS22405	COG1802	Transcriptional regulator
E5O17_RS22415	COG4695	Portal protein
E5O17_RS22460	COG4386	tail sheath protein
E5O17_RS22490	COG4228	DNA circulation
E5O17_RS22510	COG3299	homolog of phage Mu protein gp47
E5O17_RS22515	COG3778	Protein conserved in bacteria
E5O17_RS22545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E5O17_RS22565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E5O17_RS22605	COG2315	Protein conserved in bacteria
E5O17_RS22670	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5O17_RS22690	COG2252	PERMEase
E5O17_RS22695	COG0025	NhaP-type Na H and K H
E5O17_RS22700	COG0583	DNA-binding transcription factor activity
E5O17_RS22705	COG1380	Effector of murein hydrolase LrgA
E5O17_RS22710	COG1346	cytolysis
E5O17_RS22720	COG3162	membrane
E5O17_RS22735	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E5O17_RS22740	COG0437	4 iron, 4 sulfur cluster binding
E5O17_RS22745	COG3301	Polysulphide reductase, NrfD
E5O17_RS22750	COG1138	Cytochrome C-type biogenesis protein
E5O17_RS22755	COG4235	cytochrome complex assembly
E5O17_RS22760	COG1301	dicarboxylic acid transport
E5O17_RS22765	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E5O17_RS22785	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E5O17_RS22790	COG2824	Alkylphosphonate utilization operon protein PhnA
E5O17_RS22820	COG0531	amino acid
E5O17_RS22825	COG2207	Transcriptional regulator
E5O17_RS22830	COG1982	Orn Lys Arg decarboxylase major
E5O17_RS22835	COG2169	Transcriptional regulator
E5O17_RS22850	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O17_RS22850	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5O17_RS22855	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5O17_RS22865	COG4565	transcriptional regulatory protein
E5O17_RS22870	COG3290	protein histidine kinase activity
E5O17_RS22875	COG0243	molybdopterin cofactor binding
E5O17_RS22880	COG0437	4 iron, 4 sulfur cluster binding
E5O17_RS22885	COG3302	dmso reductase anchor subunit
E5O17_RS22890	COG3381	protein complex oligomerization
E5O17_RS22915	COG2197	response regulator
E5O17_RS22950	COG0789	Transcriptional regulator
E5O17_RS22975	COG0305	Participates in initiation and elongation during chromosome replication
E5O17_RS23020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E5O17_RS23110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E5O17_RS23300	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5O17_RS23330	COG0739	heme binding
E5O17_RS23340	COG2132	Multicopper oxidase
E5O17_RS23345	COG3667	copper resistance
E5O17_RS23350	COG2372	response to copper ion
E5O17_RS23355	COG1276	copper resistance
E5O17_RS23360	COG0745	RESPONSE REGULATOR receiver
E5O17_RS23365	COG2205	protein histidine kinase activity
E5O17_RS23375	COG0210	DNA helicase
E5O17_RS23385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
E5O17_RS23395	COG1309	transcriptional regulator
E5O17_RS23410	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5O17_RS23415	COG1027	Aspartate ammonia-lyase
E5O17_RS23420	COG3030	protein affecting phage T7 exclusion by the F plasmid
E5O17_RS23425	COG0531	amino acid
E5O17_RS23465	COG5510	response to toxic substance
E5O17_RS23495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E5O17_RS23500	COG1053	succinate dehydrogenase
E5O17_RS23520	COG3264	Mechanosensitive ion channel
E5O17_RS23520	COG1511	domain protein
E5O17_RS23540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5O17_RS23565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E5O17_RS23565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E5O17_RS23570	COG0802	atpase or kinase
E5O17_RS23595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E5O17_RS23600	COG0330	HflC and HflK could
E5O17_RS23605	COG0330	HflC and HflK could
E5O17_RS23610	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E5O17_RS23625	COG0557	exoribonuclease II activity
E5O17_RS23635	COG3789	protein conserved in bacteria
E5O17_RS23655	COG3766	membrane
E5O17_RS23660	COG5463	Belongs to the UPF0441 family
E5O17_RS23665	COG0754	glutathionylspermidine amidase activity
E5O17_RS23670	COG1960	acyl-CoA dehydrogenase activity
E5O17_RS23680	COG3650	response to hydrogen peroxide
E5O17_RS23685	COG1073	alpha beta
E5O17_RS23755	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E5O17_RS23770	COG3061	Opacity-associated protein A
E5O17_RS23775	COG0545	Peptidyl-prolyl cis-trans isomerase
E5O17_RS23780	COG1113	amino acid transport
E5O17_RS23790	COG0697	spore germination
E5O17_RS23810	COG1733	regulation of RNA biosynthetic process
E5O17_RS23825	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E5O17_RS23835	COG1253	flavin adenine dinucleotide binding
E5O17_RS23855	COG2105	PFAM AIG2 family protein
E5O17_RS23860	COG2271	Major facilitator Superfamily
E5O17_RS23865	COG3964	amidohydrolase
E5O17_RS23880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E5O17_RS23885	COG0837	glucose binding
E5O17_RS23885	COG1737	Transcriptional regulator
E5O17_RS23890	COG0477	Major facilitator Superfamily
E5O17_RS23890	COG2814	Major facilitator Superfamily
E5O17_RS23900	COG0477	Major facilitator Superfamily
E5O17_RS23900	COG2814	Major facilitator Superfamily
E5O17_RS23905	COG3718	enzyme involved in inositol metabolism
E5O17_RS23935	COG5520	Belongs to the glycosyl hydrolase 30 family
E5O17_RS23940	COG1082	Xylose isomerase domain protein TIM barrel
E5O17_RS23950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5O17_RS23955	COG3962	Belongs to the TPP enzyme family
E5O17_RS23960	COG0673	inositol 2-dehydrogenase activity
E5O17_RS23965	COG2814	Major facilitator Superfamily
E5O17_RS23975	COG1082	Xylose isomerase domain protein TIM barrel
E5O17_RS23985	COG0312	modulator of DNA gyrase
E5O17_RS24020	COG3964	amidohydrolase
E5O17_RS24035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5O17_RS24035	COG3711	transcriptional antiterminator
E5O17_RS24040	COG3077	Addiction module antitoxin, RelB DinJ family
E5O17_RS24045	COG2026	Addiction module toxin, RelE StbE family
E5O17_RS24060	COG0366	Alpha amylase catalytic
E5O17_RS24115	COG1438	arginine binding
E5O17_RS24120	COG1288	antiporter activity
E5O17_RS24140	COG2731	YhcH YjgK YiaL family protein
E5O17_RS24180	COG2927	DNA polymerase III (CHI subunit)
E5O17_RS24190	COG0795	lipopolysaccharide-transporting ATPase activity
E5O17_RS24195	COG0795	lipopolysaccharide-transporting ATPase activity
E5O17_RS24200	COG1609	Transcriptional regulator
E5O17_RS24205	COG2610	gluconate transmembrane transporter activity
E5O17_RS24210	COG1028	Short-chain dehydrogenase reductase Sdr
E5O17_RS24215	COG1063	alcohol dehydrogenase
E5O17_RS24220	COG3265	gluconokinase activity
E5O17_RS24225	COG1064	alcohol dehydrogenase
E5O17_RS24235	COG0582	viral genome integration into host DNA
E5O17_RS24240	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E5O17_RS24240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5O17_RS24265	COG4133	protoheme IX ABC transporter activity
E5O17_RS24300	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E5O17_RS24330	COG0412	Dienelactone hydrolase
E5O17_RS24335	COG2186	Transcriptional regulator
E5O17_RS24355	COG0583	DNA-binding transcription factor activity
E5O17_RS24360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5O17_RS24365	COG0700	Nucleoside recognition
E5O17_RS24370	COG3366	ferrous iron transmembrane transporter activity
E5O17_RS24375	COG0477	Major facilitator Superfamily
E5O17_RS24380	COG2733	membrane
E5O17_RS24390	COG5464	transposase or invertase
E5O17_RS24395	COG1012	belongs to the aldehyde dehydrogenase family
E5O17_RS24430	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
E5O17_RS24435	COG1715	Restriction endonuclease
E5O17_RS24450	COG0523	cobalamin synthesis protein
E5O17_RS24455	COG2879	small protein
E5O17_RS24460	COG1966	Carbon starvation protein
E5O17_RS24465	COG0840	transmembrane signaling receptor activity
E5O17_RS24480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5O17_RS24485	COG3715	PTS system
E5O17_RS24490	COG3716	PTS system mannose fructose sorbose family IID component
E5O17_RS24495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E5O17_RS24515	COG1484	DNA-dependent DNA replication
E5O17_RS24530	COG2966	Psort location CytoplasmicMembrane, score
E5O17_RS24535	COG2197	response regulator
E5O17_RS24540	COG2197	response regulator
E5O17_RS24545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E5O17_RS24550	COG4114	ferric iron reductase
E5O17_RS24555	COG3706	GGDEF domain
E5O17_RS24585	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E5O17_RS24595	COG1011	Hydrolase
E5O17_RS24605	COG2823	Periplasmic or secreted lipoprotein
E5O17_RS24615	COG4667	esterase of the alpha-beta hydrolase superfamily
E5O17_RS24620	COG0084	hydrolase, TatD family'
E5O17_RS24625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5O17_RS24630	COG1328	CTP reductase activity
E5O17_RS24660	COG3188	usher protein
E5O17_RS24665	COG3121	Chaperone
E5O17_RS24670	COG3539	Fimbrial protein
E5O17_RS24685	COG3726	membrane protein affecting hemolysin expression
E5O17_RS24690	COG0560	Phosphoserine phosphatase
E5O17_RS24705	COG0488	(ABC) transporter
E5O17_RS24730	COG2207	Transcriptional regulator
E5O17_RS24730	COG3708	Transcriptional regulator
E5O17_RS24735	COG3045	CreA protein
E5O17_RS24740	COG0745	RESPONSE REGULATOR receiver
E5O17_RS24745	COG2205	protein histidine kinase activity
E5O17_RS24750	COG4452	Inner membrane protein CreD
E5O17_RS24770	COG3121	Chaperone
E5O17_RS24790	COG0745	RESPONSE REGULATOR receiver
E5O17_RS24800	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E5O17_RS24905	COG4245	von Willebrand factor, type A
E5O17_RS24910	COG4245	von Willebrand factor, type A
E5O17_RS24940	COG1358	cellular component organization or biogenesis
E5O17_RS25030	COG3550	peptidyl-serine autophosphorylation
E5O17_RS25345	COG4221	oxidoreductase activity
E5O17_RS25395	COG1660	Displays ATPase and GTPase activities
E5O17_RS25475	COG3173	Aminoglycoside phosphotransferase
E5O17_RS25535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5O17_RS25535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E5O17_RS25555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5O17_RS25900	COG2890	protein-(glutamine-N5) methyltransferase activity
E5O17_RS25960	COG2433	Pfam Transposase IS66
E5O17_RS25965	COG3436	PFAM IS66 Orf2 family protein
E5O17_RS26070	COG1192	Involved in chromosome partitioning
E5O17_RS26105	COG3039	Transposase
E5O17_RS26155	COG0210	DNA helicase
E5O17_RS26230	COG3613	nucleoside 2-deoxyribosyltransferase
E5O17_RS26320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E5O17_RS26485	COG0305	Participates in initiation and elongation during chromosome replication
E5O17_RS26525	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E5O17_RS26605	COG3385	transposase activity
E5O17_RS26645	COG3133	Outer membrane lipoprotein
E5O17_RS26705	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E5O17_RS26715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
