locus-tag class description G9X25_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) G9X25_RS00015 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) G9X25_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) G9X25_RS00030 ENOG4105CXK mandelate racemase muconate lactonizing G9X25_RS00035 ENOG4105DJB Major Facilitator Superfamily G9X25_RS00040 ENOG410667J hydrolase G9X25_RS00060 ENOG4105BZU Histidine kinase G9X25_RS00065 ENOG4108SV3 Tmao reductase system periplasmic protein tort G9X25_RS00070 ENOG4106WF9 DNA-binding transcriptional regulator TorR G9X25_RS00075 ENOG4105CUW cytochrome C-TYPE protein G9X25_RS00080 ENOG4108EM1 reductase G9X25_RS00090 ENOG4105CA0 peroxidase G9X25_RS00100 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) G9X25_RS00105 ENOG41060IM Heme exporter protein G9X25_RS00110 ENOG4105X3C heme exporter protein G9X25_RS00130 ENOG4105KWW Biogenesis protein G9X25_RS00135 ENOG4105D99 atp gtp-binding protein G9X25_RS00140 ENOG4105R2A (LipO)protein G9X25_RS00165 ENOG4105VG5 Membrane G9X25_RS00170 ENOG4105JP4 Inner membrane protein yidG G9X25_RS00175 ENOG4105J13 transcriptional regulator G9X25_RS00190 ENOG4105W8I Transcriptional regulator G9X25_RS00200 ENOG4105E5M Multidrug resistance protein D G9X25_RS00225 ENOG4105C7K acetolactate synthase G9X25_RS00230 ENOG4105M71 acetolactate synthase 1 regulatory subunit G9X25_RS00235 ENOG4107FB0 transcriptional regulator DeoR family G9X25_RS00245 ENOG4105EDR glucose galactose transporter G9X25_RS00255 ENOG4108KX4 response regulator G9X25_RS00260 ENOG4105BZU Histidine kinase G9X25_RS00265 ENOG4105CXY transporter G9X25_RS00270 ENOG4105CXY transporter G9X25_RS00275 ENOG4108SAJ Protein of unknown function (DUF1198) G9X25_RS00290 ENOG41090UW PTS System G9X25_RS00295 ENOG4105DT3 PTS system, galactitol-specific IIc component G9X25_RS00305 ENOG4105D2N Aldolase G9X25_RS00340 ENOG4105CS2 ec 3.2.1.21 G9X25_RS00360 ENOG4105DAS pts system G9X25_RS00365 ENOG4105ETZ PTS System G9X25_RS00370 ENOG4105F3R pts system mannose fructose sorbose family iid G9X25_RS00385 ENOG4105DNE Transposase G9X25_RS00390 ENOG4108UZ3 Transporter G9X25_RS00400 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic G9X25_RS00415 ENOG4105CHJ isochorismatase hydrolase G9X25_RS00425 ENOG4108TC1 Transcriptional regulator G9X25_RS00430 ENOG4105FV3 G9X25_RS00440 ENOG4105ISV protein with bipartite regulator domain G9X25_RS00475 ENOG4105CT4 transporter G9X25_RS00480 ENOG4105CJQ hydrolase, family 31 G9X25_RS00485 ENOG4105JV1 AsmA family G9X25_RS00490 ENOG4105C2W permease G9X25_RS00495 ENOG4105D6U Sodium Glutamate Symporter G9X25_RS00500 ENOG4105CB5 ATP-dependent DNA helicase recG G9X25_RS00505 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase G9X25_RS00510 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) G9X25_RS00530 ENOG4105EN6 Membrane G9X25_RS00545 ENOG4105DSJ YicC domain protein G9X25_RS00550 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) G9X25_RS00570 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase G9X25_RS00600 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase G9X25_RS00605 ENOG4105DKP glycosyl transferase, family 9 G9X25_RS00610 ENOG4107RJ7 Glycosyl transferase (Group 1 G9X25_RS00615 ENOG4107543 (lipo)polysaccharide G9X25_RS00625 ENOG4107XU6 Glycosyl transferase (Group 1 G9X25_RS00630 ENOG4106AH0 Glycosyl Transferase G9X25_RS00635 ENOG4105X1N Glycosyl transferase family 8 G9X25_RS00640 ENOG4108PDR lipopolysaccharide core biosynthesis protein G9X25_RS00645 ENOG4108QD8 lipopolysaccharide core biosynthesis protein G9X25_RS00650 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase G9X25_RS00655 ENOG4108FRV O-antigen ligase G9X25_RS00660 ENOG4105D16 lipopolysaccharide heptosyltransferase i G9X25_RS00665 ENOG4105XA0 heptosyltransferase ii G9X25_RS00675 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) G9X25_RS00685 ENOG4105K64 Glycosyl transferase, family 2 G9X25_RS00690 ENOG4105PXI polysaccharide deacetylase G9X25_RS00695 ENOG41063SB peptidase G9X25_RS00705 ENOG4107YZP Rhodanese domain protein G9X25_RS00710 ENOG4105VW4 glutaredoxin 3 G9X25_RS00715 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) G9X25_RS00720 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase G9X25_RS00725 ENOG4105D7W serine acetyltransferase G9X25_RS00730 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) G9X25_RS00740 ENOG41073TP transcriptional regulator G9X25_RS00745 ENOG4105DAA L-lactate G9X25_RS00750 ENOG4105EUR Domain-Containing protein G9X25_RS00755 ENOG4108WY4 inner membrane lipoprotein G9X25_RS00760 ENOG4108YYI Protein of unknown function (DUF2810) G9X25_RS00770 ENOG4105E61 Mannitol repressor protein G9X25_RS00780 ENOG4105CTS PTS system mannitol-specific G9X25_RS00785 ENOG4105FP6 Protein of unknown function (DUF3302) G9X25_RS00790 ENOG4105EFX secretion protein, HlyD family G9X25_RS00795 ENOG4108U78 Glutathione S-transferase G9X25_RS00805 ENOG4105EM7 Selenocysteine-specific translation elongation factor G9X25_RS00810 ENOG4105C0A alcohol dehydrogenase G9X25_RS00815 ENOG41066F8 ROK family G9X25_RS00820 ENOG4105C26 Dehydrogenase G9X25_RS00835 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase G9X25_RS00840 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase G9X25_RS00845 ENOG4105H6Q decarboxylase G9X25_RS00850 ENOG4105CMG Carbohydrate kinase G9X25_RS00855 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit G9X25_RS00860 ENOG4105CG6 trap dicarboxylate transporter dctm subunit G9X25_RS00865 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter G9X25_RS00870 ENOG4108M5W G9X25_RS00875 ENOG4108R66 Conserved Protein G9X25_RS00885 ENOG4105J4Q Transcriptional regulator G9X25_RS00890 ENOG4108XIB electron transport protein ysaA G9X25_RS00895 ENOG4105JKW Valine--pyruvate aminotransferase G9X25_RS00900 ENOG4107T9C Alpha amylase catalytic region G9X25_RS00905 ENOG4108UR8 BAX protein G9X25_RS00910 ENOG4105T16 Transcriptional regulator (AraC family) G9X25_RS00920 ENOG4105CMG Carbohydrate kinase G9X25_RS00925 ENOG410688U Inner membrane protein yiaB G9X25_RS00930 ENOG4105MEV Acyl-transferase G9X25_RS00935 ENOG4105RGS lipoprotein ysaB G9X25_RS00960 ENOG4105MVF Transcriptional regulator G9X25_RS00965 ENOG4106JH6 (LipO)protein G9X25_RS00975 ENOG4108ZG0 Ompa motb domain protein G9X25_RS00980 ENOG4107QY8 reductase G9X25_RS00985 ENOG4105HNP -acetyltransferase G9X25_RS00990 ENOG4108R3E Dna-3-methyladenine glycosylase i G9X25_RS00995 ENOG4105EAX Putative lipase G9X25_RS01000 ENOG4105DIJ Phosphoethanolamine transferase G9X25_RS01035 ENOG4105DEF Extracellular solute-binding protein, family 5 G9X25_RS01040 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component G9X25_RS01045 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component G9X25_RS01050 ENOG4105C3U ABC transporter G9X25_RS01055 ENOG4108JQ7 (ABC) transporter G9X25_RS01060 ENOG4105C44 Serine transporter G9X25_RS01080 ENOG4105D1V cellulose synthase operon protein YhjU G9X25_RS01085 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT G9X25_RS01095 ENOG410661M cytoplasmic protein G9X25_RS01100 ENOG4105UTS cellulose synthase operon protein YhjQ G9X25_RS01105 ENOG4107QZ7 Cellulose synthase catalytic subunit G9X25_RS01110 ENOG4107EEX Cellulose synthase regulator protein G9X25_RS01115 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) G9X25_RS01120 ENOG4105EJG cellulose synthase G9X25_RS01125 ENOG4105BZU Histidine kinase G9X25_RS01135 ENOG4105CS0 peptidase G9X25_RS01140 ENOG4107SS6 2-dehydro-3-deoxygluconokinase G9X25_RS01145 ENOG4105CMB EAL domain-containing protein G9X25_RS01150 ENOG41066T0 asmA family G9X25_RS01155 ENOG4105CSH Transporter G9X25_RS01160 ENOG4107H3J ribonuclease G9X25_RS01165 ENOG4105CBN LysR family transcriptional regulator G9X25_RS01170 ENOG4106S2D Transcriptional regulator G9X25_RS01190 ENOG4105FDP GntR family transcriptional regulator G9X25_RS01205 ENOG4105DC8 reductase G9X25_RS01210 ENOG4105D6S protein involved in catabolism of external DNA G9X25_RS01215 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase G9X25_RS01220 ENOG4105DGW oligopeptidase A G9X25_RS01230 ENOG4105DUX Transporter G9X25_RS01235 ENOG4108M6U Universal stress protein A G9X25_RS01245 ENOG4105CJ3 phosphate transporter G9X25_RS01250 ENOG4105CBX hi0933 family G9X25_RS01255 ENOG4105D0S secretion protein (HlyD G9X25_RS01260 ENOG4105CJ1 ABC, transporter G9X25_RS01265 ENOG4105CMI transporter G9X25_RS01275 ENOG4107YAK holo-(acyl carrier protein) synthase 2 G9X25_RS01280 ENOG4105DSF transport protein G9X25_RS01290 ENOG4108W1V Lipoprotein G9X25_RS01295 ENOG4105EX9 Membrane G9X25_RS01305 ENOG4105C8Q Methyl-accepting chemotaxis G9X25_RS01315 ENOG4107FS9 Membrane G9X25_RS01325 ENOG4105MG3 Membrane G9X25_RS01330 ENOG4106H78 methyltransferase G9X25_RS01335 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) G9X25_RS01340 ENOG4105CAK Cell division ATP-binding protein ftsE G9X25_RS01345 ENOG4105CRP Part of the ABC transporter FtsEX involved in G9X25_RS01355 ENOG4105CP9 extracellular ligand-binding receptor G9X25_RS01365 ENOG4105U59 -acetyltransferase G9X25_RS01370 ENOG4105CP9 extracellular ligand-binding receptor G9X25_RS01375 ENOG4105C32 Amino acid ABC transporter (Permease) G9X25_RS01380 ENOG4105CF8 branched-chain amino acid ABC transporter, permease G9X25_RS01385 ENOG4105C0Z ABC transporter G9X25_RS01390 ENOG4108IV0 ABC, transporter G9X25_RS01395 ENOG41060M8 Pfam:PhdYeFM G9X25_RS01405 ENOG4105BZ7 extracellular solute-binding protein family 1 G9X25_RS01410 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component G9X25_RS01425 ENOG4107T6V glycerophosphoryl diester phosphodiesterase G9X25_RS01430 ENOG4105WC8 Conserved Protein G9X25_RS01435 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) G9X25_RS01440 ENOG41080QX K07048 phosphotriesterase-related protein G9X25_RS01455 ENOG4108RVA ribokinase G9X25_RS01460 ENOG4105WCN acetyltransferase G9X25_RS01465 ENOG4105D9R oxidoreductase G9X25_RS01470 ENOG4105C2I pirin domain protein G9X25_RS01475 ENOG4105DIQ Transcriptional regulator G9X25_RS01480 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family G9X25_RS01485 ENOG4105C6Z Gluconate G9X25_RS01495 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) G9X25_RS01520 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) G9X25_RS01535 ENOG4105C6V Glycerol-3-phosphate dehydrogenase G9X25_RS01550 ENOG4105E98 transcriptional regulator DeoR family G9X25_RS01560 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) G9X25_RS01565 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) G9X25_RS01570 ENOG4105C6Z Gluconate G9X25_RS01580 ENOG4105MJ2 Competence protein G9X25_RS01590 ENOG4105DNE Transposase G9X25_RS01605 ENOG4105XFK Ferrous iron transport protein A G9X25_RS01610 ENOG4105BZM domain protein G9X25_RS01615 ENOG4108RRZ Transcription elongation factor GreB G9X25_RS01625 ENOG4105E0F Histidine kinase G9X25_RS01635 ENOG4108MAJ Membrane G9X25_RS01645 ENOG4105VEJ Heat shock protein G9X25_RS01650 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 G9X25_RS01660 ENOG4107RK2 ADP-ribose diphosphatase NudE G9X25_RS01665 ENOG4108JQC penicillin-binding protein 1A G9X25_RS01670 ENOG4108U1Q Pilus assembly protein G9X25_RS01675 ENOG41065NF Fimbrial assembly family protein G9X25_RS01695 ENOG4105EGB membrane protein DamX G9X25_RS01700 ENOG4105DFE Dna adenine methylase G9X25_RS01705 ENOG4105DJV ribulose-phosphate 3-epimerase G9X25_RS01715 ENOG4105C31 Tryptophanyl-tRNA synthetase G9X25_RS01720 ENOG4105VYH G9X25_RS01725 ENOG4107EF2 surface-exposed virulence protein G9X25_RS01735 ENOG4107V9H nitrite transporter G9X25_RS01740 ENOG4105WZK nitrite reductase NADPH small subunit G9X25_RS01745 ENOG4107QZF nitrite reductase NADPH large subunit G9X25_RS01755 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) G9X25_RS01760 ENOG4106195 uncharacterized protein yhfG G9X25_RS01765 ENOG4105MZU cell filamentation protein G9X25_RS01770 ENOG4105DDQ anthranilate synthase G9X25_RS01775 ENOG4105C8Y Acetylornithine aminotransferase G9X25_RS01780 ENOG410613R integral membrane protein, YccS YhfK family G9X25_RS01785 ENOG4107RYR Transcriptional regulator, Crp Fnr family G9X25_RS01790 ENOG4108UKZ OsmC family G9X25_RS01795 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) G9X25_RS01805 ENOG4105DNZ Alpha Beta Hydrolase G9X25_RS01810 ENOG4105N0V mono-oxygenase ydhR G9X25_RS01815 ENOG4108K70 Transcriptional regulator G9X25_RS01820 ENOG4105C5H ABC transporter G9X25_RS01835 ENOG4105VKU nucleicacid-binding protein G9X25_RS01840 ENOG4108YZY peptidylprolyl cis-trans isomerase G9X25_RS01845 ENOG4105VRX Protein slyX homolog G9X25_RS01850 ENOG4108V1T peptidylprolyl cis-trans isomerase G9X25_RS01855 ENOG4105WWK YheO domain protein G9X25_RS01890 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) G9X25_RS01895 ENOG4105W53 bacterioferritin-associated ferredoxin G9X25_RS01900 ENOG4108UQY Iron-storage protein G9X25_RS01905 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) G9X25_RS01935 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) G9X25_RS01955 ENOG41083MP 50s ribosomal protein l29 G9X25_RS01960 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal G9X25_RS01970 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) G9X25_RS01995 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) G9X25_RS02005 ENOG4105VPB 50S ribosomal protein L30 G9X25_RS02015 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) G9X25_RS02020 ENOG41067V7 50S ribosomal protein L36 G9X25_RS02035 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) G9X25_RS02050 ENOG4105VTS DnaJ-like, subfamily C G9X25_RS02055 ENOG4105W1Y Transcriptional regulator G9X25_RS02060 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system G9X25_RS02065 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) G9X25_RS02070 ENOG4105C1A potassium transporter peripheral membrane G9X25_RS02090 ENOG4105C79 DNA protecting protein DprA G9X25_RS02100 ENOG4108WI1 Dna topoisomerase G9X25_RS02115 ENOG4105SG3 Protein of unknown function (DUF1488) G9X25_RS02120 ENOG4108Z0R Transferase G9X25_RS02155 ENOG4105XCM membrane LIPOPROTEIN G9X25_RS02160 ENOG4105BZS acriflavin resistance protein G9X25_RS02165 ENOG4105C1P efflux transporter, rnd family, mfp subunit G9X25_RS02170 ENOG4108XG4 DNA-binding transcriptional regulator G9X25_RS02175 ENOG4105BZU Histidine kinase G9X25_RS02180 ENOG41061ME transport protein G9X25_RS02185 ENOG4105CEC DNA methylase N-4 N-6 G9X25_RS02195 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) G9X25_RS02205 ENOG4108IA2 Sodium pantothenate symporter G9X25_RS02210 ENOG4105RG0 Membrane G9X25_RS02215 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase G9X25_RS02220 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein G9X25_RS02235 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family G9X25_RS02240 ENOG41062P1 Diguanylate cyclase phosphodiesterase G9X25_RS02250 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) G9X25_RS02255 ENOG4105VQ7 Rod shape-determining protein MreD G9X25_RS02260 ENOG4108Z03 MAF-like protein G9X25_RS02265 ENOG4105C03 ribonuclease G9X25_RS02270 ENOG4105QD6 exported protein G9X25_RS02275 ENOG4105D1U peptidase U62 modulator of DNA gyrase G9X25_RS02280 ENOG4105CR8 Transcriptional regulator G9X25_RS02285 ENOG4105ZQC membrane protein AaeX G9X25_RS02300 ENOG4105UNR (Barnase) inhibitor G9X25_RS02305 ENOG4105RID UPF0379 protein yhcN G9X25_RS02310 ENOG4105RID UPF0379 protein yhcN G9X25_RS02335 ENOG4105C8P )-transporter G9X25_RS02340 ENOG4106DSS Tartrate dehydratase subunit alpha G9X25_RS02345 ENOG4107GFK fumarate G9X25_RS02355 ENOG4107QSA Oxaloacetate decarboxylase G9X25_RS02360 ENOG4105D9Q decarboxylase (Beta subunit) G9X25_RS02375 ENOG4105C0H protease G9X25_RS02380 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III G9X25_RS02385 ENOG4105D6Z AFG1 family ATPase G9X25_RS02405 ENOG4107MKT Stringent starvation protein a G9X25_RS02410 ENOG4105KB2 stringent starvation protein b G9X25_RS02440 ENOG4108R66 Conserved Protein G9X25_RS02445 ENOG4105DZC cytosine deaminase G9X25_RS02450 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin G9X25_RS02455 ENOG4105DFS Conserved Protein G9X25_RS02460 ENOG4105BZ8 glutamate synthase G9X25_RS02465 ENOG4105CBC glutamate synthase G9X25_RS02470 ENOG4105N5T Radical SAM Protein G9X25_RS02475 ENOG4105BZU Histidine kinase G9X25_RS02480 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain G9X25_RS02490 ENOG4108NIH transferase activity, transferring phosphorus-containing groups G9X25_RS02495 ENOG41080Z8 PHOSPHOCARRIER protein G9X25_RS02505 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN G9X25_RS02510 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA G9X25_RS02515 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) G9X25_RS02520 ENOG4108IUZ ABC transporter G9X25_RS02525 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA G9X25_RS02530 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) G9X25_RS02535 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase G9X25_RS02540 ENOG4105C2X Arabinose 5-phosphate isomerase G9X25_RS02545 ENOG4105FEU K -dependent Na -Ca exchanger G9X25_RS02550 ENOG4105DHJ ABC, transporter G9X25_RS02555 ENOG4105CY3 ABC transporter, permease G9X25_RS02560 ENOG4107PE3 Mammalian cell entry related domain protein G9X25_RS02565 ENOG4105E3I toluene tolerance G9X25_RS02570 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane G9X25_RS02575 ENOG4105VFK BolA family G9X25_RS02585 ENOG4105HVQ Regulatory factor of maltose metabolism G9X25_RS02590 ENOG4105EAH synthase G9X25_RS02600 ENOG4105K46 50S ribosomal protein l27 G9X25_RS02605 ENOG4105QYV Membrane G9X25_RS02615 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase G9X25_RS02620 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) G9X25_RS02625 ENOG4105HBR Rna-binding protein G9X25_RS02635 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) G9X25_RS02640 ENOG4105EEI dihydropteroate synthase G9X25_RS02650 ENOG4105NTZ Preprotein translocase subunit SecG G9X25_RS02670 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) G9X25_RS02675 ENOG4105CHV Transcription elongation factor NusA G9X25_RS02715 ENOG4105C1J atp-dependent rna helicase G9X25_RS02720 ENOG4105CIC tryptophan-specific transport protein G9X25_RS02725 ENOG4105DEN Luciferase family G9X25_RS02745 ENOG4108YYD acetyltransferase G9X25_RS02760 ENOG4107R7Y intracellular protease Pfpi family G9X25_RS02765 ENOG4105K4T epimerase G9X25_RS02770 ENOG4105W4M Transport-associated protein G9X25_RS02785 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) G9X25_RS02790 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) G9X25_RS02800 ENOG4107WTH Galactitol-1-phosphate dehydrogenase G9X25_RS02810 ENOG41090UW PTS System G9X25_RS02815 ENOG41082GB PTS system galactitol-specific transporter subunit IIA G9X25_RS02830 ENOG4105CTX dehydratase G9X25_RS02840 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase G9X25_RS02845 ENOG4105BZW Glycerate kinase G9X25_RS02875 ENOG410811B TRANSCRIPTIONal G9X25_RS02880 ENOG4105C7B Threonine dehydratase G9X25_RS02895 ENOG4105C6N Formate acetyltransferase G9X25_RS02900 ENOG4105EJQ L-serine dehydratase G9X25_RS02905 ENOG4105C44 Serine transporter G9X25_RS02915 ENOG4106D80 Uncharacterized protein YhaL G9X25_RS02920 ENOG4108CNN domain protein G9X25_RS02925 ENOG4105CWB LysR family transcriptional Regulator G9X25_RS02930 ENOG4105KAF membrAne G9X25_RS02935 ENOG4105CHF Glutathione S-transferase G9X25_RS02940 ENOG4108VBZ doxx family G9X25_RS02945 ENOG4105YJD G9X25_RS02950 ENOG41090KG Inner membrane protein YqjE G9X25_RS02955 ENOG4105NE1 Conserved Protein G9X25_RS02960 ENOG4105WAY exported protein G9X25_RS02970 ENOG4106W5V Membrane G9X25_RS02980 ENOG4105DU1 integral membrane protein, terc G9X25_RS02985 ENOG4105EE0 oxidoreductase G9X25_RS02990 ENOG4108UB4 uncharacterized protein ygjQ G9X25_RS02995 ENOG4108VKG metal-dependent hydrolase G9X25_RS03005 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase G9X25_RS03015 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor G9X25_RS03020 ENOG4105C8Q Methyl-accepting chemotaxis G9X25_RS03025 ENOG4105NTW Transcriptional regulator G9X25_RS03030 ENOG4105Q26 Siderophore-interacting protein G9X25_RS03040 ENOG4108VCA G U mismatch-specific DNA glycosylase G9X25_RS03045 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) G9X25_RS03050 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) G9X25_RS03075 ENOG4107ZVW dihydroneopterin aldolase G9X25_RS03090 ENOG4106MWK domain protein G9X25_RS03095 ENOG4105I7R Adenylate cyclase G9X25_RS03115 ENOG4107S78 Band 7 protein G9X25_RS03120 ENOG4105PV3 Inner membrane protein yqiJ G9X25_RS03130 ENOG4105W0Z cytoplasmic protein G9X25_RS03140 ENOG4108PSN Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity) G9X25_RS03150 ENOG4108MR7 Arylsulfotransferase G9X25_RS03160 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b G9X25_RS03165 ENOG4106032 Glutathionylspermidine synthase G9X25_RS03170 ENOG4105F1G UPF0441 protein G9X25_RS03180 ENOG41087AY ADP-Ribose pyrophosphatase G9X25_RS03185 ENOG4108SX3 cytoplasmic protein G9X25_RS03190 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) G9X25_RS03195 ENOG4105IPS esterase G9X25_RS03200 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) G9X25_RS03205 ENOG4105VRH Antibiotic biosynthesis monooxygenase G9X25_RS03210 ENOG4105NF4 modulator of drug activity G9X25_RS03215 ENOG4105DHQ Histidine kinase G9X25_RS03220 ENOG4105XJC Two component transcriptional regulator (Winged helix family G9X25_RS03225 ENOG4105H4F exported protein G9X25_RS03230 ENOG4105F4I Transcriptional regulator G9X25_RS03235 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) G9X25_RS03240 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase G9X25_RS03245 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) G9X25_RS03250 ENOG4105CG6 trap dicarboxylate transporter dctm subunit G9X25_RS03260 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit G9X25_RS03265 ENOG4105CCT upf0313 protein G9X25_RS03280 ENOG4107QPK )-transporter G9X25_RS03285 ENOG4105CV8 reductase G9X25_RS03290 ENOG4108I6A alcohol dehydrogenase G9X25_RS03295 ENOG4105CF7 AraC family transcriptional regulator G9X25_RS03300 ENOG4108K81 inner membrane protein YghB G9X25_RS03305 ENOG4105C28 cystathionine G9X25_RS03310 ENOG4105CWK Biopolymer transport protein, ExbB G9X25_RS03315 ENOG4108ZZF transport protein (ExbD) G9X25_RS03320 ENOG4105CYX Short-chain dehydrogenase reductase Sdr G9X25_RS03345 ENOG4105C8Q Methyl-accepting chemotaxis G9X25_RS03350 ENOG410900S Protein of unknown function (DUF2623) G9X25_RS03355 ENOG4105E3S small subunit G9X25_RS03360 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G9X25_RS03365 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit G9X25_RS03370 ENOG4105DPX Hydrogenase, large subunit G9X25_RS03375 ENOG4108USZ hydrogenase G9X25_RS03380 ENOG4108WGS hydrogenase 2-specific chaperone G9X25_RS03385 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) G9X25_RS03390 ENOG41082MF Hydrogenase assembly chaperone hypC hupF G9X25_RS03395 ENOG4105S10 periplasmic binding protein G9X25_RS03400 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein G9X25_RS03405 ENOG4105CYM Glutathione S-transferase G9X25_RS03410 ENOG4106032 Glutathionylspermidine synthase G9X25_RS03425 ENOG4105DEI Mannitol dehydrogenase G9X25_RS03435 ENOG4105DPW Major facilitator superfamily MFS_1 G9X25_RS03460 ENOG4105C26 Dehydrogenase G9X25_RS03465 ENOG4105CJP fad dependent oxidoreductase G9X25_RS03475 ENOG4105CUB amino acid G9X25_RS03485 ENOG4108UAJ Transcriptional regulator G9X25_RS03490 ENOG4105E3J oxidoreductase G9X25_RS03495 ENOG41066GK UPF0379 protein ykgI G9X25_RS03500 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) G9X25_RS03515 ENOG4108UQV Membrane G9X25_RS03520 ENOG4105CXN decarboxylase G9X25_RS03525 ENOG4105EAA nucleoside G9X25_RS03535 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) G9X25_RS03540 ENOG4105CEN a g-specific adenine glycosylase G9X25_RS03550 ENOG41090ED Protein with unknown function (DUF469) G9X25_RS03555 ENOG4105K33 Periplasmic Protein G9X25_RS03560 ENOG4105HDK L-asparaginase G9X25_RS03565 ENOG4106MH3 alpha helix chain G9X25_RS03570 ENOG4105CSA Coproporphyrinogen iii oxidase G9X25_RS03585 ENOG4108VIA integral membrane protein G9X25_RS03590 ENOG4105DFA alanine racemase domain protein G9X25_RS03595 ENOG4105CZX twitching motility protein G9X25_RS03615 ENOG4105D7Z glutathione synthase G9X25_RS03620 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) G9X25_RS03625 ENOG4105RWS endonuclease I G9X25_RS03635 ENOG4107QNK )-transporter G9X25_RS03660 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) G9X25_RS03670 ENOG4107YCY Transcriptional regulator G9X25_RS03680 ENOG4105DEI Mannitol dehydrogenase G9X25_RS03685 ENOG4105CPQ Dehydrogenase G9X25_RS03690 ENOG4105DG4 malate L-lactate dehydrogenase G9X25_RS03695 ENOG4108R66 Conserved Protein G9X25_RS03700 ENOG4108J2P Alpha beta hydrolase fold G9X25_RS03710 ENOG4108K0D peptidase, M48 G9X25_RS03715 ENOG4105CV1 Transketolase (EC 2.2.1.1) G9X25_RS03720 ENOG4108JJB ABC transporter G9X25_RS03725 ENOG4108JJB ABC transporter G9X25_RS03750 ENOG4105BZA Phosphoglycerate kinase G9X25_RS03755 ENOG4105D2N Aldolase G9X25_RS03760 ENOG4105D64 Mechanosensitive ion channel G9X25_RS03770 ENOG4105MPN Membrane G9X25_RS03785 ENOG4108JQ1 Dehydrogenase G9X25_RS03790 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase G9X25_RS03810 ENOG4107RAQ aminopeptidase G9X25_RS03815 ENOG4105D0A hydroxylase G9X25_RS03820 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family G9X25_RS03845 ENOG4105CS2 ec 3.2.1.21 G9X25_RS03855 ENOG4108UT2 hemolysin iii G9X25_RS03870 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB G9X25_RS03875 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) G9X25_RS03880 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) G9X25_RS03885 ENOG4105T95 Thiol disulfide interChange protein G9X25_RS03890 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) G9X25_RS03910 ENOG4108K5P (LipO)protein G9X25_RS03930 ENOG4108T1M outer membrane protein x G9X25_RS03950 ENOG4106P2F Pfam:Pili_assembly_C G9X25_RS03980 ENOG4108MHD transport protein G9X25_RS03990 ENOG4105C5Q Transcriptional regulator G9X25_RS03995 ENOG4105CHU acetyl-coa acetyltransferase G9X25_RS04005 ENOG4105CHR reductase G9X25_RS04010 ENOG4107QNK )-transporter G9X25_RS04020 ENOG4105RQF LysR family Transcriptional regulator G9X25_RS04030 ENOG4105DDV Transcriptional regulator (LacI family G9X25_RS04050 ENOG4105CPC Aldo Keto reductase G9X25_RS04055 ENOG4105SUV lipoprotein YgdR G9X25_RS04060 ENOG4105EE5 Membrane protein terC G9X25_RS04075 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase G9X25_RS04090 ENOG4105IPU prepilin peptidase dependent protein A G9X25_RS04095 ENOG4105JCS prepilin peptidase dependent protein G9X25_RS04100 ENOG4105SEN Protein of unknown function (DUF2509) G9X25_RS04105 ENOG4105RVB Prepilin peptidase dependent protein c G9X25_RS04110 ENOG4105DSY exodeoxyribonuclease V, gamma G9X25_RS04115 ENOG4107QXK peptidase G9X25_RS04120 ENOG4107QKA exodeoxyribonuclease V beta G9X25_RS04125 ENOG4107QYX exodeoxyribonuclease v alpha G9X25_RS04130 ENOG4108EKC n-acetylglutamate synthase G9X25_RS04135 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase G9X25_RS04150 ENOG4105CA3 membrane-bound lytic murein transglycosylase G9X25_RS04155 ENOG4105CUZ uba thif-type nad fad binding protein G9X25_RS04160 ENOG4105FR1 rard protein G9X25_RS04165 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) G9X25_RS04170 ENOG4105C9B Cysteine desulfurase G9X25_RS04175 ENOG4105M5B (LipO)protein G9X25_RS04180 ENOG4105ETT transcriptional Regulator, LysR family G9X25_RS04185 ENOG4105M08 Membrane G9X25_RS04195 ENOG4107EDW L-fucose operon activator G9X25_RS04205 ENOG4105CMG Carbohydrate kinase G9X25_RS04215 ENOG4105EDR glucose galactose transporter G9X25_RS04220 ENOG4107W7X Aldolase G9X25_RS04225 ENOG4105C0A alcohol dehydrogenase G9X25_RS04235 ENOG4105EJQ L-serine dehydratase G9X25_RS04240 ENOG4105C44 Serine transporter G9X25_RS04245 ENOG4105EWT decarboxylase family G9X25_RS04260 ENOG4105WP7 tRNA pseudouridine synthase C G9X25_RS04265 ENOG4105DR9 pseudouridine synthase G9X25_RS04270 ENOG4105QDK Flavodoxin G9X25_RS04275 ENOG4105DJB Major Facilitator Superfamily G9X25_RS04280 ENOG4105EQX glucarate dehydratase G9X25_RS04285 ENOG4105EQX glucarate dehydratase G9X25_RS04290 ENOG4105BZW Glycerate kinase G9X25_RS04295 ENOG4105BZU Histidine kinase G9X25_RS04300 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) G9X25_RS04305 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) G9X25_RS04320 ENOG4105DXN mazG family G9X25_RS04330 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) G9X25_RS04335 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) G9X25_RS04340 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) G9X25_RS04345 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase G9X25_RS04350 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) G9X25_RS04370 ENOG4105DTT CRISPR-associated helicase, cas3 G9X25_RS04375 ENOG4105CYR Crispr-associated protein, cse1 family G9X25_RS04385 ENOG41060M0 Crispr-associated protein, cse4 family G9X25_RS04390 ENOG4108VWQ crispr-associated protein G9X25_RS04400 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) G9X25_RS04405 ENOG4105PWE CRISPR-associated protein cas2 G9X25_RS04410 ENOG4108MXK alkaline phosphatase isozyme conversion G9X25_RS04430 ENOG4105N0Z inner membrane protein ygbE G9X25_RS04465 ENOG4108K5P (LipO)protein G9X25_RS04475 ENOG4105KZM cytoplasmic protein G9X25_RS04480 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) G9X25_RS04485 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase G9X25_RS04495 ENOG4105MVE transcriptional regulator G9X25_RS04505 ENOG4105G63 Type III effector Hrp-dependent G9X25_RS04515 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) G9X25_RS04520 ENOG4105EXW epimerase dehydratase G9X25_RS04525 ENOG4105C6Z Gluconate G9X25_RS04530 ENOG4105JQN Transcriptional regulator G9X25_RS04535 ENOG4105C0R drug resistance transporter emrb qaca subfamily G9X25_RS04555 ENOG4105MEW serine threonine protein phosphatase G9X25_RS04585 ENOG41090HZ type iii secretion G9X25_RS04595 ENOG4108N8R Invasion protein G9X25_RS04600 ENOG4108HR8 type iii secretion G9X25_RS04605 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone G9X25_RS04610 ENOG4108JIR Flagellum-specific ATP synthase G9X25_RS04615 ENOG41077MC Secretory protein (Associated with virulence) G9X25_RS04620 ENOG41078G4 surface presentation of G9X25_RS04625 ENOG4105T85 surface presentation of antigens protein G9X25_RS04630 ENOG41075IY surface presentation of antigens protein SpaP G9X25_RS04635 ENOG4105U07 type iii secretion G9X25_RS04640 ENOG4108TN6 type iii secretion G9X25_RS04645 ENOG4108M6W surface presentation of antigens protein SpaS G9X25_RS04655 ENOG4106H1J Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE G9X25_RS04665 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC G9X25_RS04675 ENOG41079WB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) G9X25_RS04690 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear G9X25_RS04700 ENOG4108YAB Invasion protein G9X25_RS04710 ENOG4108RC9 Type III secretion system protein G9X25_RS04715 ENOG4105Y7Q type iii secretion G9X25_RS04720 ENOG4106BTR G9X25_RS04725 ENOG4108RBT type iii secretion G9X25_RS04760 ENOG4105CC5 ABC transporter G9X25_RS04765 ENOG4105CC5 ABC transporter G9X25_RS04770 ENOG4105DIK (ABC) transporter G9X25_RS04780 ENOG4105VXR cytoplasmic protein G9X25_RS04790 ENOG4105C45 hydrogenase expression formation protein (HypE) G9X25_RS04795 ENOG4105CQS hydrogenase expression formation protein HypD G9X25_RS04800 ENOG41083WG hydrogenase assembly chaperone G9X25_RS04805 ENOG4107RSS Hydrogenase accessory protein HypB G9X25_RS04810 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) G9X25_RS04815 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA G9X25_RS04820 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) G9X25_RS04825 ENOG4107R30 NADH dehydrogenase G9X25_RS04830 ENOG4107TDF Formate hydrogenlyase subunit 4 G9X25_RS04835 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) G9X25_RS04840 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit G9X25_RS04845 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit G9X25_RS04850 ENOG4105I6X formate hydrogenlyase maturation G9X25_RS04855 ENOG4108MG9 hydrogenase 3 maturation protease G9X25_RS04865 ENOG4108RC0 Electron transport protein G9X25_RS04870 ENOG4105C8H hydrogenase maturation protein Hypf G9X25_RS04890 ENOG4105C2X Arabinose 5-phosphate isomerase G9X25_RS04895 ENOG410804X Transcriptional regulator G9X25_RS04900 ENOG4105J92 DNA-binding transcriptional activator GutM G9X25_RS04905 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase G9X25_RS04910 ENOG4105VI0 Pts system, glucitol sorbitol-specific G9X25_RS04915 ENOG4105DZY Pts system, glucitol sorbitol-specific G9X25_RS04920 ENOG410787A Pts system, glucitol sorbitol-specific G9X25_RS04925 ENOG4105CVE Lytic murein transglycosylase G9X25_RS04930 ENOG4107TH8 cina domain protein G9X25_RS04945 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) G9X25_RS04950 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) G9X25_RS04980 ENOG4107VXZ Hydrolase G9X25_RS04985 ENOG4105W39 Membrane G9X25_RS05005 ENOG4105C0R drug resistance transporter emrb qaca subfamily G9X25_RS05010 ENOG4105CW7 secretion protein, HlyD family G9X25_RS05015 ENOG4105NTK Transcriptional repressor Mpra G9X25_RS05025 ENOG4105GIJ Glycine betaine G9X25_RS05030 ENOG4108HQS Glycine betaine G9X25_RS05035 ENOG4108IJ7 Glycine betaine G9X25_RS05040 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) G9X25_RS05045 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) G9X25_RS05055 ENOG4105WAZ (Glutaredoxin-like protein) NrdH G9X25_RS05060 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) G9X25_RS05070 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) G9X25_RS05075 ENOG4108WMJ Protein of unknown function (DUF2002) G9X25_RS05080 ENOG4108RNS Exports L-alanine (By similarity) G9X25_RS05085 ENOG4108X73 DNA- binding protein G9X25_RS05095 ENOG4108V62 Rhodanese domain protein G9X25_RS05100 ENOG41080HT Transcriptional regulator, arsr family G9X25_RS05105 ENOG4105VPI YqaE family transport protein G9X25_RS05110 ENOG4109066 lysm domain bon superfamily protein G9X25_RS05115 ENOG4108PVQ transcriptional regulator G9X25_RS05120 ENOG4105C85 amino acid G9X25_RS05125 ENOG4108JPW Aminotransferase G9X25_RS05130 ENOG4105C26 Dehydrogenase G9X25_RS05135 ENOG4105D5U fad dependent oxidoreductase G9X25_RS05180 ENOG4108MJ5 VirK protein G9X25_RS05190 ENOG4107RNH Outer membrane receptor FepA G9X25_RS05195 ENOG4105NIV Esterase G9X25_RS05215 ENOG4108C33 Resolvase G9X25_RS05220 ENOG4105I03 Flagellin G9X25_RS05255 ENOG4105BZ1 (ABC) transporter G9X25_RS05275 ENOG4108Z1B Cyclase dehydrase G9X25_RS05285 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) G9X25_RS05290 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) G9X25_RS05310 ENOG4108JU6 CBS domain protein G9X25_RS05315 ENOG4106KVJ cytochrome C assembly protein G9X25_RS05320 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY G9X25_RS05345 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) G9X25_RS05350 ENOG4108KHX Diguanylate cyclase G9X25_RS05355 ENOG4108WS1 G9X25_RS05360 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) G9X25_RS05365 ENOG4105EHE chorismate mutase- prephenate dehydrogenase G9X25_RS05375 ENOG4105CQC Prephenate dehydratase G9X25_RS05385 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA G9X25_RS05390 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane G9X25_RS05395 ENOG4105C34 Pseudouridine synthase G9X25_RS05400 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase G9X25_RS05405 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit G9X25_RS05440 ENOG4105CSH Transporter G9X25_RS05445 ENOG4105T42 (LipO)protein G9X25_RS05450 ENOG4105JIM Phosphatidylserine synthase G9X25_RS05455 ENOG4105CD5 CoA-binding domain protein G9X25_RS05460 ENOG4106IUH DTW domain containing protein G9X25_RS05465 ENOG4105K63 Thioredoxin G9X25_RS05470 ENOG4105EIB trna rrna methyltransferase G9X25_RS05480 ENOG4108VKA Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity) G9X25_RS05490 ENOG41090KR LysR family transcriptional Regulator G9X25_RS05495 ENOG4105C1J atp-dependent rna helicase G9X25_RS05505 ENOG4108IYU L-aspartate oxidase G9X25_RS05530 ENOG4105WMJ Positive regulator of sigma E, RseC MucC G9X25_RS05555 ENOG41076J9 exonuclease VIII G9X25_RS05590 ENOG4105JBR DNA replication protein G9X25_RS05615 ENOG4105MEA DNA damage-inducible protein i G9X25_RS05640 ENOG4105HGD Antitermination protein G9X25_RS05650 ENOG4105NVB glycoside hydrolase, family 19 G9X25_RS05655 ENOG4108YV9 Protein of unknown function (DUF2514) G9X25_RS05670 ENOG4108N0N Phage Terminase Large Subunit G9X25_RS05815 ENOG4105C3F Signal peptidase i G9X25_RS05825 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) G9X25_RS05845 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding G9X25_RS05850 ENOG4105DND Transcriptional regulator G9X25_RS05860 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) G9X25_RS05865 ENOG4106G6Q Transcriptional regulator G9X25_RS05880 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB G9X25_RS05885 ENOG4108Z6B deaminase G9X25_RS05890 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) G9X25_RS05905 ENOG4107WP9 Histidine kinase G9X25_RS05910 ENOG4108SKK alpha helix protein G9X25_RS05915 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family G9X25_RS05925 ENOG4105DUX Transporter G9X25_RS05930 ENOG4105CXN decarboxylase G9X25_RS05935 ENOG4105D5Q Arginine ornithine antiporter G9X25_RS05940 ENOG4108M3R transcriptional activator CadC G9X25_RS05945 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) G9X25_RS05955 ENOG4105D8G Major Facilitator superfamily G9X25_RS05960 ENOG4108MN2 Stationary phase inducible protein CsiE G9X25_RS05970 ENOG4105D7X high-affinity nickel-transporter G9X25_RS05975 ENOG410810Y Sulfite reductase G9X25_RS05980 ENOG4107SHJ sulfite reductase subunit b G9X25_RS05985 ENOG4105D5B Sulfite reductase, subunit A G9X25_RS05990 ENOG4107XM9 (LipO)protein G9X25_RS05995 ENOG4105ECY inositol monophosphatase G9X25_RS06000 ENOG4105CVS RNA methyltransferase TrmH family, group 1 G9X25_RS06015 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins G9X25_RS06020 ENOG4108Z4V iron-sulfur cluster assembly G9X25_RS06035 ENOG4108ZIT Ferredoxin, 2FE-2S G9X25_RS06040 ENOG4105WVQ Fe-S assembly protein IscX G9X25_RS06050 ENOG4105YYA enhanced serine sensitivity protein SseB G9X25_RS06060 ENOG4105KHC sulfurtransferase G9X25_RS06065 ENOG4105DN3 alpha-2-macroglobulin domain protein G9X25_RS06070 ENOG4108JQB penicillin-binding protein 1C G9X25_RS06075 ENOG4107QY8 reductase G9X25_RS06080 ENOG4105QAX Iron-sulfur G9X25_RS06120 ENOG4105N21 Membrane G9X25_RS06125 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) G9X25_RS06135 ENOG4105VPD cellular component movement G9X25_RS06170 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) G9X25_RS06195 ENOG41062G3 Protein of unknown function (DUF2633) G9X25_RS06205 ENOG4105BZU Histidine kinase G9X25_RS06210 ENOG4105C9X ppx gppa phosphatase G9X25_RS06215 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) G9X25_RS06220 ENOG4108V3E phosphoribosylglycinamide formyltransferase G9X25_RS06230 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) G9X25_RS06235 ENOG4105C2W permease G9X25_RS06245 ENOG4105K89 arsenate reductase G9X25_RS06250 ENOG4105ERG peptidase m48, ste24p G9X25_RS06255 ENOG4105C02 permease G9X25_RS06260 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR G9X25_RS06265 ENOG4107QQ0 gntp family G9X25_RS06270 ENOG4105BZW Glycerate kinase G9X25_RS06275 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen G9X25_RS06280 ENOG4105RH4 Glycine cleavage system transcriptional repressor G9X25_RS06290 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) G9X25_RS06300 ENOG4105CGZ zinc metallopeptidase G9X25_RS06305 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) G9X25_RS06315 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) G9X25_RS06320 ENOG4105KUZ arsenate reductase G9X25_RS06330 ENOG4105BZS acriflavin resistance protein G9X25_RS06335 ENOG4105BZU Histidine kinase G9X25_RS06340 ENOG4105BZ8 glutamate synthase G9X25_RS06350 ENOG4107VIJ nudix hydrolase G9X25_RS06355 ENOG4108PVD exported protein G9X25_RS06365 ENOG4105CV1 Transketolase (EC 2.2.1.1) G9X25_RS06370 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) G9X25_RS06375 ENOG4105C6K Malic enzyme G9X25_RS06380 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place G9X25_RS06385 ENOG4106S4J ethanolamine utilization protein EutP G9X25_RS06390 ENOG4105NDK ethanolamine utilization protein G9X25_RS06395 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase G9X25_RS06400 ENOG4108IJ2 phosphate acetyltransferase G9X25_RS06405 ENOG4105KNY Microcompartments protein G9X25_RS06410 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml G9X25_RS06415 ENOG4108EKI Dehydrogenase G9X25_RS06420 ENOG4107YMV ethanolamine utilization protein G9X25_RS06425 ENOG4105C0A alcohol dehydrogenase G9X25_RS06430 ENOG4105ENY Ethanolamine utilization protein eutH G9X25_RS06435 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase G9X25_RS06440 ENOG4105CPD ethanolamine ammonia-lyase G9X25_RS06450 ENOG4106D67 ethanolamine utilization protein G9X25_RS06455 ENOG4108X49 Ethanolamine utilization protein EutK G9X25_RS06460 ENOG4108K3Z AraC family transcriptional regulator G9X25_RS06470 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase G9X25_RS06475 ENOG4108R6G acetyltransferase G9X25_RS06480 ENOG4105QZU Inner membrane protein YfeZ G9X25_RS06485 ENOG4105E7K (LipO)protein G9X25_RS06490 ENOG4105EZR dyp-type peroxidase family protein G9X25_RS06495 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr G9X25_RS06500 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein G9X25_RS06505 ENOG4108I5D sulfate abc transporter G9X25_RS06510 ENOG4105ECW sulfate abc transporter G9X25_RS06515 ENOG4108IJ6 ABC transporter G9X25_RS06520 ENOG4105C6T cysteine synthase G9X25_RS06525 ENOG4105M0Y G9X25_RS06530 ENOG41089BK Glutamine amido-transferase G9X25_RS06535 ENOG4105CSW GntR family transcriptional regulator G9X25_RS06540 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) G9X25_RS06550 ENOG4105C5Y PTS System G9X25_RS06555 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) G9X25_RS06565 ENOG4105C6T cysteine synthase G9X25_RS06585 ENOG4105VRT cytoplasmic protein G9X25_RS06590 ENOG4105DHU Bile acid G9X25_RS06595 ENOG4108M0I Transcriptional regulator G9X25_RS06600 ENOG4108NFH Sugar hydrolase G9X25_RS06605 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) G9X25_RS06610 ENOG4105EAA nucleoside G9X25_RS06620 ENOG4105CN8 Transcriptional regulator G9X25_RS06650 ENOG4105GXM Putative transcription regulator (DUF1323) G9X25_RS06655 ENOG4105HZG regulatoR G9X25_RS06670 ENOG4108KMM Diguanylate cyclase G9X25_RS06675 ENOG4105D9N nucleoside G9X25_RS06685 ENOG4109076 Conserved Protein G9X25_RS06690 ENOG4105CPC Aldo Keto reductase G9X25_RS06695 ENOG4107RA9 decarboxylase G9X25_RS06710 ENOG4105CHM Aminotransferase G9X25_RS06720 ENOG4105D1S lipid A biosynthesis G9X25_RS06725 ENOG4105W9M Membrane G9X25_RS06730 ENOG4105CXY transporter G9X25_RS06735 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC G9X25_RS06745 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta G9X25_RS06750 ENOG4108NC2 Outer membrane protease G9X25_RS06760 ENOG4105S64 Formate nitrite transporter G9X25_RS06765 ENOG410903C (LipO)protein G9X25_RS06770 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation G9X25_RS06775 ENOG4105KZW UPF0381 protein G9X25_RS06790 ENOG4108BY2 phosphohistidine phosphatase G9X25_RS06800 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) G9X25_RS06815 ENOG4105EJ9 Membrane G9X25_RS06820 ENOG4108BPE -transporting atpase G9X25_RS06825 ENOG4105MH2 YfcL protein G9X25_RS06830 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) G9X25_RS06835 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) G9X25_RS06855 ENOG4105R8V Transcriptional regulator G9X25_RS06870 ENOG4106WZ1 flagella biosynthesis regulator G9X25_RS06880 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) G9X25_RS06890 ENOG4105DQR SNARE associated Golgi G9X25_RS06900 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase G9X25_RS06905 ENOG4108S3P Sporulation domain protein G9X25_RS06910 ENOG4105E96 Colicin v production protein G9X25_RS06915 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase G9X25_RS06920 ENOG4108JUB Transcriptional regulator G9X25_RS06930 ENOG4105E5D amino acid G9X25_RS06935 ENOG4106M28 alanine racemase domain protein G9X25_RS06940 ENOG4108IQI permease G9X25_RS06945 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase G9X25_RS06950 ENOG4105E89 ABC transporter G9X25_RS06955 ENOG4105E89 ABC transporter G9X25_RS06960 ENOG4105DSP amino acid AbC transporter G9X25_RS06965 ENOG4106YG3 ABC transporter G9X25_RS06970 ENOG4108JEH abc transporter atp-binding protein G9X25_RS06975 ENOG4105ECP epimerase G9X25_RS06980 ENOG4105CYM Glutathione S-transferase G9X25_RS06985 ENOG4108SHQ Glutathione S-transferase G9X25_RS06990 ENOG4108RE9 Phosphodiesterase G9X25_RS06995 ENOG4105PTV Nudix Hydrolase G9X25_RS07000 ENOG4105K2J Transcriptional regulator G9X25_RS07005 ENOG4106ETB IIa component G9X25_RS07015 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC G9X25_RS07020 ENOG4108HHA Transketolase G9X25_RS07025 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) G9X25_RS07030 ENOG4105CSX c4-dicarboxylate anaerobic carrier G9X25_RS07035 ENOG4105C6K Malic enzyme G9X25_RS07040 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) G9X25_RS07055 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 G9X25_RS07060 ENOG4107QWE )-transporter G9X25_RS07070 ENOG4105CHM Aminotransferase G9X25_RS07075 ENOG4107NQ8 LysR family Transcriptional regulator G9X25_RS07085 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain G9X25_RS07090 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) G9X25_RS07100 ENOG4105GKE subunit e G9X25_RS07105 ENOG4107QIZ NADH dehydrogenase G9X25_RS07110 ENOG4108IEH NADH dehydrogenase subunit g G9X25_RS07125 ENOG4107UFS subunit j G9X25_RS07135 ENOG4105D65 subunit l G9X25_RS07140 ENOG4105C8S subunit m G9X25_RS07160 ENOG4107YB6 acetyltransferase, (GNAT) family G9X25_RS07165 ENOG4105TNS Conserved Protein G9X25_RS07170 ENOG4105E4F Isochorismate synthase G9X25_RS07185 ENOG4108IPT Naphthoate synthase G9X25_RS07195 ENOG4105CEY Amp-dependent synthetase and ligase G9X25_RS07200 ENOG4106GZG polymyxin resistance protein B G9X25_RS07250 ENOG4108UII YfaZ family G9X25_RS07255 ENOG4108EWA cinA-like protein G9X25_RS07265 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) G9X25_RS07275 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A G9X25_RS07280 ENOG4105CXY transporter G9X25_RS07285 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase G9X25_RS07290 ENOG4105GZI Transcriptional regulator G9X25_RS07295 ENOG4105CZM Major Facilitator G9X25_RS07300 ENOG4105XPH Ferredoxin G9X25_RS07305 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) G9X25_RS07310 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) G9X25_RS07330 ENOG4105CXK mandelate racemase muconate lactonizing G9X25_RS07335 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) G9X25_RS07340 ENOG4105BZU Histidine kinase G9X25_RS07345 ENOG41068CG regulatoR G9X25_RS07350 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC G9X25_RS07355 ENOG4105FCK Membrane G9X25_RS07360 ENOG4105CJ2 (LipO)protein G9X25_RS07365 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) G9X25_RS07370 ENOG4105CF1 Alkylated DNA repair protein G9X25_RS07375 ENOG4105IBP Cyclic peptide transporter G9X25_RS07385 ENOG4108ZNS ferredoxin-type protein NapF G9X25_RS07390 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase G9X25_RS07400 ENOG4108BGM Quinol dehydrogenase periplasmic component G9X25_RS07405 ENOG4105GXZ Ferredoxin-type protein NapH G9X25_RS07410 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) G9X25_RS07415 ENOG4105CUW cytochrome C-TYPE protein G9X25_RS07450 ENOG4107QX9 Thiol disulfide interChange protein G9X25_RS07455 ENOG4105KWW Biogenesis protein G9X25_RS07460 ENOG4105WH1 Two component transcriptional regulator luxr family G9X25_RS07480 ENOG4105E68 Sulfatase G9X25_RS07505 ENOG4105CFI type iii restriction protein res subunit G9X25_RS07510 ENOG4105I08 Pseudouridine synthase G9X25_RS07515 ENOG4105C2C drug resistance transporter, Bcr CflA G9X25_RS07520 ENOG4105HG6 G9X25_RS07525 ENOG4108JQ5 ABC transporter G9X25_RS07530 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component G9X25_RS07535 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component G9X25_RS07540 ENOG4105E43 Extracellular solute-binding protein, family 5 G9X25_RS07545 ENOG4105CXC rtn protein G9X25_RS07550 ENOG4107TT5 NLP P60 protein G9X25_RS07555 ENOG41076MN Phosphoesterase, PA-phosphatase related G9X25_RS07560 ENOG4105CKI cobalamin synthesis protein G9X25_RS07565 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) G9X25_RS07570 ENOG4105KRS Proteinase inhibitor G9X25_RS07585 ENOG4105S8Q sugar efflux transporter G9X25_RS07590 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein G9X25_RS07595 ENOG4105DE4 1-phosphofructokinase G9X25_RS07600 ENOG4105DM4 PTS System G9X25_RS07610 ENOG4105HMI Membrane G9X25_RS07615 ENOG4105DUM transcriptional regulator, lysR family G9X25_RS07620 ENOG4108IQI permease G9X25_RS07625 ENOG4105D05 Receptor G9X25_RS07630 ENOG4105CXY transporter G9X25_RS07635 ENOG4105EAC phosphoserine phosphatase G9X25_RS07640 ENOG4105EJQ L-serine dehydratase G9X25_RS07655 ENOG4105EUJ GTP cyclohydrolase i G9X25_RS07660 ENOG4105DHF Membrane G9X25_RS07665 ENOG41060NJ transcriptional regulator G9X25_RS07670 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator G9X25_RS07675 ENOG4105C2J ABC transporter G9X25_RS07680 ENOG4107SDZ Galactoside transport system permease protein mglC G9X25_RS07685 ENOG4107SJI Dehydrogenase G9X25_RS07690 ENOG4105BZ8 glutamate synthase G9X25_RS07695 ENOG4105Y9N Membrane G9X25_RS07700 ENOG4107GZ4 SanA protein G9X25_RS07710 ENOG41067MG lrgb family G9X25_RS07740 ENOG4108RXX maleylacetoacetate isomerase G9X25_RS07745 ENOG4105MSY salicylate hydroxylase G9X25_RS07750 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) G9X25_RS07760 ENOG4105ETP RND efflux system, outer membrane lipoprotein G9X25_RS07765 ENOG4105H9W Short-chain dehydrogenase reductase Sdr G9X25_RS07770 ENOG4105KHU inner membrane protein YohD G9X25_RS07775 ENOG41069YE inner membrane protein yohC G9X25_RS07780 ENOG41061WM D-Alanyl-D-Alanine G9X25_RS07785 ENOG4105CXG d-lactate dehydrogenase G9X25_RS07790 ENOG4107QK4 glycoside hydrolase, family 3 domain protein G9X25_RS07795 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system G9X25_RS07800 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component G9X25_RS07805 ENOG4108IJ8 ABC transporter G9X25_RS07810 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component G9X25_RS07825 ENOG4108HRK Histidine kinase G9X25_RS07830 ENOG4108NEV two component transcriptional regulator, LytTR family G9X25_RS07835 ENOG4108W15 Protein of unknown function (DUF1456) G9X25_RS07840 ENOG4108YCW (LipO)protein G9X25_RS07845 ENOG4108YCW (LipO)protein G9X25_RS07855 ENOG4105D1F ATP-binding protein G9X25_RS07870 ENOG4108MQF Chaperone G9X25_RS07875 ENOG4105CW0 outer membrane usher protein G9X25_RS07880 ENOG410662B Type-1 fimbrial protein G9X25_RS07885 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly G9X25_RS07895 ENOG4105DWF phosphomethylpyrimidine kinase G9X25_RS07900 ENOG4105FDP GntR family transcriptional regulator G9X25_RS07905 ENOG4108TFM Kinase, PfkB family G9X25_RS07910 ENOG4108KD5 ADP-ribosylation crystallin J1 G9X25_RS07915 ENOG4105EAA nucleoside G9X25_RS07920 ENOG4105EIE fructose-bisphosphate aldolase G9X25_RS07935 ENOG41090V3 Tir chaperone protein (CesT) family G9X25_RS07945 ENOG4105CFP Peptidase U32 G9X25_RS07965 ENOG4105E3W Two component transcriptional regulator (Winged helix family G9X25_RS07970 ENOG4105EB3 Histidine kinase G9X25_RS08000 ENOG4105R8A Heat shock protein G9X25_RS08005 ENOG4105D03 DNA-3-methyladenine glycosylase II G9X25_RS08010 ENOG4105BZU Histidine kinase G9X25_RS08025 ENOG4108GAE asmA family G9X25_RS08030 ENOG4105EE5 Membrane protein terC G9X25_RS08035 ENOG4105DAY polysaccharide export protein G9X25_RS08040 ENOG4105KJF protein tyrosine phosphatase G9X25_RS08045 ENOG4105D75 Capsular exopolysaccharide family G9X25_RS08050 ENOG41090RK glycosyl transferase G9X25_RS08055 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB G9X25_RS08060 ENOG4107RXY Glycosyl transferase G9X25_RS08065 ENOG4108NYJ Colanic acid G9X25_RS08070 ENOG4105ECJ Glycosyl Transferase G9X25_RS08075 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF G9X25_RS08080 ENOG4105C0K Gdp-mannose 4,6-dehydratase G9X25_RS08085 ENOG4105C30 Nad-dependent epimerase dehydratase G9X25_RS08095 ENOG4106CD9 glycosyl transferase group 1 G9X25_RS08100 ENOG4105CJT Mannose-1-phosphate guanylyltransferase G9X25_RS08105 ENOG4107QKV phosphomannomutase G9X25_RS08110 ENOG4105D3Q Sugar transferase G9X25_RS08115 ENOG4105PSV Polysaccharide Biosynthesis Protein G9X25_RS08120 ENOG4105C74 pyruvyl transferase G9X25_RS08125 ENOG4107T8Q Glycosyl transferase (Group 1 G9X25_RS08130 ENOG4105G1A colanic acid biosynthesis protein G9X25_RS08135 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase G9X25_RS08140 ENOG4105CMR udp-glucose 4-epimerase G9X25_RS08145 ENOG4105CGN Glycosyl transferase (Group 1 G9X25_RS08150 ENOG4105C0K Gdp-mannose 4,6-dehydratase G9X25_RS08155 ENOG4105C30 Nad-dependent epimerase dehydratase G9X25_RS08165 ENOG4105CJT Mannose-1-phosphate guanylyltransferase G9X25_RS08195 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) G9X25_RS08200 ENOG4105C6Y Udp-glucose 6-dehydrogenase G9X25_RS08205 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) G9X25_RS08210 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase G9X25_RS08225 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) G9X25_RS08230 ENOG4105ECC imidazole-glycerol-phosphate dehydratase G9X25_RS08255 ENOG4107SRH Nad-dependent epimerase dehydratase G9X25_RS08260 ENOG4105EQ1 Transcriptional regulator G9X25_RS08270 ENOG4105CUB amino acid G9X25_RS08275 ENOG4105CJB Exodeoxyribonuclease I G9X25_RS08290 ENOG4108J2R molybdopterin oxidoreductase G9X25_RS08295 ENOG4105QAX Iron-sulfur G9X25_RS08300 ENOG4108NWD Cytochrome G9X25_RS08305 ENOG4105DZ1 carboxypeptidase G9X25_RS08310 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) G9X25_RS08315 ENOG4105DR8 Membrane G9X25_RS08320 ENOG41090HJ UPF0265 protein G9X25_RS08325 ENOG4105JZC GHMP kinase G9X25_RS08330 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) G9X25_RS08335 ENOG4105KTW ethanolamine utilization protein G9X25_RS08340 ENOG4105M3W utilization protein G9X25_RS08350 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) G9X25_RS08355 ENOG4105C0A alcohol dehydrogenase G9X25_RS08360 ENOG4108EKI Dehydrogenase G9X25_RS08370 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml G9X25_RS08380 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) G9X25_RS08390 ENOG4105KNY Microcompartments protein G9X25_RS08400 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit G9X25_RS08405 ENOG4108ZFT Dehydratase small subunit G9X25_RS08410 ENOG4105YCI dehydratase medium subunit G9X25_RS08415 ENOG4105DMB glycerol dehydratase G9X25_RS08420 ENOG4105EHR propanediol utilization protein pduB G9X25_RS08425 ENOG4105KNY Microcompartments protein G9X25_RS08430 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) G9X25_RS08435 ENOG4107XVH Transcriptional regulator G9X25_RS08440 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) G9X25_RS08450 ENOG41081F0 Precorrin-8x methylmutase G9X25_RS08460 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase G9X25_RS08465 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase G9X25_RS08470 ENOG4105CIA precorrin-4 C(11)-methyltransferase G9X25_RS08475 ENOG4108P62 biosynthesis protein (CbiG) G9X25_RS08480 ENOG4105E4R Precorrin-3B C17-methyltransferase G9X25_RS08485 ENOG4105QUC reductase G9X25_RS08490 ENOG4107PPM cobalt chelatase G9X25_RS08495 ENOG4105DVK Precorrin-2 c20-methyltransferase G9X25_RS08500 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) G9X25_RS08505 ENOG4105W4R Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) G9X25_RS08510 ENOG4108V4M Cobalt abc transporter G9X25_RS08515 ENOG4108JJB ABC transporter G9X25_RS08520 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) G9X25_RS08525 ENOG4108YZT Adenosylcobinamide kinase G9X25_RS08540 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein G9X25_RS08550 ENOG4105UQX Mate efflux family protein G9X25_RS08575 ENOG4105FYV Amp nucleosidase G9X25_RS08580 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein G9X25_RS08585 ENOG4105KVH Transcriptional regulator G9X25_RS08630 ENOG4105KT5 UmuD protein G9X25_RS08635 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) G9X25_RS08650 ENOG4105FCK Membrane G9X25_RS08655 ENOG4105Y0K Inner membrane protein YedR G9X25_RS08660 ENOG4105EST Metal Dependent Phosphohydrolase G9X25_RS08665 ENOG4105DVF Cytosine-specific methyltransferase G9X25_RS08670 ENOG41090BB DNA mismatch endonuclease (vsr) G9X25_RS08675 ENOG4105FDR Membrane G9X25_RS08680 ENOG4105CKW Inner membrane protein yedI G9X25_RS08685 ENOG4105VNZ cytoplasmic protein G9X25_RS08695 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase G9X25_RS08700 ENOG4105YX3 cellular response to acidity G9X25_RS08710 ENOG4107TKS colanic acid capsular biosynthesis activation protein A G9X25_RS08715 ENOG4105D19 Role in flagellar biosynthesis (By similarity) G9X25_RS08720 ENOG4105VS8 Flagellar biosynthetic protein fliq G9X25_RS08725 ENOG4105CN7 Flagellar biosynthetic protein FliP G9X25_RS08730 ENOG4105K0P flagellar biosynthesis protein G9X25_RS08735 ENOG4105DD5 Flagellar motor switch protein G9X25_RS08740 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) G9X25_RS08745 ENOG4107ZI8 flagellar basal body-associated protein flil G9X25_RS08750 ENOG4105WF4 Flagellar hook-length control protein G9X25_RS08755 ENOG4105GSA Flagellar export protein flij G9X25_RS08760 ENOG4108JIR Flagellum-specific ATP synthase G9X25_RS08765 ENOG41090PJ Flagellar assembly protein G9X25_RS08770 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) G9X25_RS08775 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) G9X25_RS08795 ENOG41066VF YeeE YedE family protein G9X25_RS08800 ENOG4105JCU Inherit from NOG: (Lipo)protein G9X25_RS08805 ENOG4105E5K Alpha-amylase G9X25_RS08815 ENOG4105MQ3 flagellar protein FliS G9X25_RS08820 ENOG4105DTS flagellar hook-associated G9X25_RS08830 ENOG4108C80 FliB family G9X25_RS08835 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) G9X25_RS08840 ENOG4108M9K flagella biosynthesis protein FliZ G9X25_RS08845 ENOG4105EAB amino acid AbC transporter G9X25_RS08855 ENOG4105E5Q amino acid AbC transporter G9X25_RS08860 ENOG4105CDA abc transporter atp-binding protein G9X25_RS08865 ENOG4105VJY transcriptional regulator G9X25_RS08870 ENOG4105XVG cytoplasmic protein G9X25_RS08880 ENOG4105WH1 Two component transcriptional regulator luxr family G9X25_RS08925 ENOG4106RHG Yeca family G9X25_RS08930 ENOG4105E0U tyrosine-specific transport protein G9X25_RS08935 ENOG4105VVZ metal-binding protein G9X25_RS08940 ENOG41090A1 ferritin G9X25_RS08945 ENOG4105P23 (LipO)protein G9X25_RS08955 ENOG4108UEC Ferritin-like protein G9X25_RS08970 ENOG4108K4C ec 3.1.3.12 G9X25_RS08980 ENOG4108VA4 Universal stress protein G9X25_RS08995 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region G9X25_RS09000 ENOG4107RD7 Flagellar Motor Protein, MotA G9X25_RS09005 ENOG4105ER2 Ompa motb domain protein G9X25_RS09010 ENOG4105CBS Chea signal transduction histidine kinase G9X25_RS09015 ENOG4108V3W Chemotaxis protein, CheW G9X25_RS09020 ENOG4105C8Q Methyl-accepting chemotaxis G9X25_RS09025 ENOG4105BZU Histidine kinase G9X25_RS09030 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) G9X25_RS09035 ENOG4108VYJ response regulator receiver protein G9X25_RS09040 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) G9X25_RS09045 ENOG4105D00 flagellar biosynthetic protein flhB G9X25_RS09050 ENOG4105D7B Flagellar biosynthesis protein flha G9X25_RS09055 ENOG4105IRD Flagellar protein FlhE G9X25_RS09060 ENOG4105F5H Glycosyl Hydrolase Family 88 G9X25_RS09075 ENOG4106ZCM YecM protein G9X25_RS09095 ENOG4105WJG Glutathione G9X25_RS09100 ENOG41081XQ Conserved Protein G9X25_RS09105 ENOG4105D3W isochorismatase G9X25_RS09115 ENOG4108TIT dATP pyrophosphohydrolase G9X25_RS09120 ENOG4105CDY transcriptional regulatory protein G9X25_RS09130 ENOG4107S01 Repressor protein MetJ G9X25_RS09150 ENOG4105FAV ABC, transporter G9X25_RS09160 ENOG4105NXV High-affinity zinc uptake system protein G9X25_RS09165 ENOG4105DR5 peptidase G9X25_RS09170 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase G9X25_RS09175 ENOG4105CA9 Pyruvate kinase G9X25_RS09180 ENOG4106KNT transcriptional regulator G9X25_RS09185 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase G9X25_RS09190 ENOG4105C01 Dihydroxy-acid dehydratase G9X25_RS09195 ENOG4108UHU Aldolase G9X25_RS09205 ENOG4105X2V dna damage-inducible protein G9X25_RS09215 ENOG4108Q2J Inner membrane protein YebE G9X25_RS09220 ENOG4105CUG Oligopeptidase b G9X25_RS09225 ENOG4105UMD exodeoxyribonuclease X G9X25_RS09230 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase G9X25_RS09235 ENOG4105MPK DNA polymerase III subunit theta G9X25_RS09240 ENOG4105FXM Copper resistance protein G9X25_RS09245 ENOG4108PNC copper resistance G9X25_RS09250 ENOG4105NKT exported protein G9X25_RS09280 ENOG41070YT Rac prophage G9X25_RS09285 ENOG4108PNI recT protein G9X25_RS09290 ENOG41076J9 exonuclease VIII G9X25_RS09340 ENOG4105ZTP Protein of unknown function (DUF1376) G9X25_RS09415 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 G9X25_RS09505 ENOG4105E9H Lytic Murein transglycosylase G9X25_RS09545 ENOG410685N tail fiber protein G9X25_RS09550 ENOG4105UZW Tail fiber assembly protein G9X25_RS09555 ENOG4105H38 Membrane G9X25_RS09565 ENOG4108I1J Integrase G9X25_RS09630 ENOG4105EUZ Beta-lactamase domain protein G9X25_RS09645 ENOG4105DWP Membrane G9X25_RS09680 ENOG41064WM Uncharacterized protein YcgX G9X25_RS09685 ENOG4106EWC guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling G9X25_RS09695 ENOG4108R1E Serine threonine protein phosphatase 1 G9X25_RS09700 ENOG4105UVW uncharacterized protein yebW G9X25_RS09705 ENOG4105WT8 Protein of unknown function (DUF1480) G9X25_RS09715 ENOG4105DY2 Paraquat-inducible protein b G9X25_RS09720 ENOG4105H2K paraquat-inducible protein a G9X25_RS09725 ENOG4108ZGC gaf domain protein G9X25_RS09735 ENOG4105CN1 protease G9X25_RS09740 ENOG4105D0M Protease HtpX homolog G9X25_RS09745 ENOG4105C0R drug resistance transporter emrb qaca subfamily G9X25_RS09750 ENOG4105J4Q Transcriptional regulator G9X25_RS09760 ENOG4106CCY Protein MgrB homolog G9X25_RS09765 ENOG4105Q3Y exported protein G9X25_RS09780 ENOG4105CJN penicillin-binding protein G9X25_RS09785 ENOG4105DHI Methyltransferase G9X25_RS09800 ENOG4105F3R pts system mannose fructose sorbose family iid G9X25_RS09805 ENOG4105ETZ PTS System G9X25_RS09810 ENOG4105DAS pts system G9X25_RS09815 ENOG4105EE5 Membrane protein terC G9X25_RS09820 ENOG4107XTP (EAL) domain protein G9X25_RS09825 ENOG4105EJQ L-serine dehydratase G9X25_RS09835 ENOG4105CRQ synthase (Component I) G9X25_RS09840 ENOG4105X5C UPF0181 protein G9X25_RS09845 ENOG4105M4H endoribonuclease L-psp G9X25_RS09850 ENOG4105DVT helicase G9X25_RS09855 ENOG41072GX Peptidase M22 Glycoprotease G9X25_RS09860 ENOG4105Y4Z Outer Membrane Lipoprotein G9X25_RS09865 ENOG4105CEY Amp-dependent synthetase and ligase G9X25_RS09870 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) G9X25_RS09880 ENOG4107QMS site-determining protein G9X25_RS09895 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase G9X25_RS09910 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation G9X25_RS09920 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) G9X25_RS09935 ENOG4105ED1 spovr family G9X25_RS09945 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) G9X25_RS09955 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A G9X25_RS09965 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) G9X25_RS09980 ENOG4105D82 Glutamate dehydrogenase G9X25_RS09990 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii G9X25_RS09995 ENOG4105C4M (Ubiquinol oxidase) subunit I G9X25_RS10000 ENOG4105MVP hydrogenase-1 operon protein HyaF G9X25_RS10005 ENOG4108VXY Hydrogenase-1 operon protein HyaE G9X25_RS10010 ENOG4108USZ hydrogenase G9X25_RS10015 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit G9X25_RS10025 ENOG4105E3S small subunit G9X25_RS10035 ENOG4105C3G gtp-binding protein G9X25_RS10045 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria G9X25_RS10050 ENOG4105CHH sulfate transporter G9X25_RS10055 ENOG4105C5T Phosphoribosyl pyrophosphate synthase G9X25_RS10060 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) G9X25_RS10070 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) G9X25_RS10080 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) G9X25_RS10085 ENOG4108YY7 Invasion gene expression up-regulator SirB G9X25_RS10090 ENOG41063JG Transcriptional regulator G9X25_RS10100 ENOG4105EWV Sodium calcium exchanger membrane region G9X25_RS10105 ENOG4105WS7 Cation transport regulator G9X25_RS10110 ENOG41090EX DsrE family G9X25_RS10115 ENOG4105ID0 Putative invasin G9X25_RS10120 ENOG4105WH1 Two component transcriptional regulator luxr family G9X25_RS10125 ENOG4105BZU Histidine kinase G9X25_RS10130 ENOG4105DQQ Major facilitator superfamily MFS_1 G9X25_RS10135 ENOG4105CRU nitrate reductase, alpha subunit G9X25_RS10140 ENOG4108IUE nitrate reductase beta subunit G9X25_RS10145 ENOG4105R3A Nitrate reductase G9X25_RS10150 ENOG41076YT nitrate reductase, gamma subunit G9X25_RS10180 ENOG4105CIY formyltetrahydrofolate deformylase G9X25_RS10185 ENOG4105K5B UPF0225 protein G9X25_RS10190 ENOG4105D78 K07001 NTE family protein G9X25_RS10195 ENOG4105I93 response regulator G9X25_RS10200 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase G9X25_RS10215 ENOG4105C0A alcohol dehydrogenase G9X25_RS10220 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein G9X25_RS10225 ENOG4107QSI ABC, transporter G9X25_RS10230 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component G9X25_RS10235 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component G9X25_RS10240 ENOG4105C3U ABC transporter G9X25_RS10245 ENOG4108JQ7 (ABC) transporter G9X25_RS10250 ENOG4105EYW Ion transport protein G9X25_RS10270 ENOG4105K9H YciI-like protein G9X25_RS10275 ENOG410822N TonB family G9X25_RS10280 ENOG4105NAU thioesterase Superfamily protein G9X25_RS10295 ENOG4105PI0 Ferredoxin G9X25_RS10300 ENOG4105EIF outer membrane protein W G9X25_RS10305 ENOG4105WEF catalase G9X25_RS10310 ENOG4108N8X transition metal ion binding G9X25_RS10315 ENOG4108Z9Z response to DNA damage stimulus G9X25_RS10335 ENOG4105DK0 Indole-3-glycerol phosphate synthase G9X25_RS10340 ENOG4108EFP Anthranilate synthase component II G9X25_RS10345 ENOG4105CRQ synthase (Component I) G9X25_RS10355 ENOG4105DB7 PHP domain protein G9X25_RS10360 ENOG4107RTD sua5 ycio yrdc ywlc family protein G9X25_RS10365 ENOG4105FE9 pseudouridine synthase G9X25_RS10370 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase G9X25_RS10375 ENOG4105UBK short-chain dehydrogenase reductase G9X25_RS10380 ENOG4105ERU peptidase G9X25_RS10385 ENOG4105RKX Protein of unknown function (DUF2498) G9X25_RS10390 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) G9X25_RS10395 ENOG4107R11 Transcriptional regulator G9X25_RS10405 ENOG4107QM5 aconitate hydratase G9X25_RS10410 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) G9X25_RS10415 ENOG4105EYK Phosphatidylglycerophosphatase B G9X25_RS10420 ENOG4105Q4A inner membrane protein yciS G9X25_RS10425 ENOG4105CFV Tetratricopeptide repeat protein G9X25_RS10435 ENOG4108ZJT translation initiation factor, Sui1 G9X25_RS10440 ENOG41061RM osmotically inducible lipoprotein G9X25_RS10445 ENOG4105N2W Transcriptional regulator G9X25_RS10455 ENOG4105BZU Histidine kinase G9X25_RS10465 ENOG4105Q4T oxidoreductase G9X25_RS10470 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH G9X25_RS10495 ENOG4108JQ2 peptide transport system atp-binding protein G9X25_RS10500 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein G9X25_RS10505 ENOG4108EU3 peptide transport system, permease G9X25_RS10545 ENOG4108C33 Resolvase G9X25_RS10550 ENOG4108EKA peptide transport system, permease G9X25_RS10555 ENOG4108J59 Extracellular solute-binding protein, family 5 G9X25_RS10560 ENOG4105E51 psp operon transcriptional activator G9X25_RS10565 ENOG41087YS Phage shock protein A G9X25_RS10570 ENOG4105YYT phage shock protein B G9X25_RS10575 ENOG4105FM1 phage shock protein C G9X25_RS10580 ENOG4105NNG Peripheral inner membrane phage-shock protein G9X25_RS10585 ENOG4105K8Z Phage shock protein G9X25_RS10590 ENOG4105CM6 amino acid regulated cytosolic protein G9X25_RS10600 ENOG4108JU8 Transcriptional regulator G9X25_RS10605 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) G9X25_RS10610 ENOG4107S8C mandelate racemase muconate lactonizing G9X25_RS10615 ENOG4105KXI murein peptide amidase A G9X25_RS10620 ENOG4107QSI ABC, transporter G9X25_RS10630 ENOG4105HEI LysR family (Transcriptional regulator G9X25_RS10635 ENOG4105CV8 reductase G9X25_RS10640 ENOG4105F6U Short-chain dehydrogenase reductase Sdr G9X25_RS10645 ENOG4108XFH Transcriptional regulator G9X25_RS10660 ENOG4106PHM regulatory protein G9X25_RS10680 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) G9X25_RS10700 ENOG4105D64 Mechanosensitive ion channel G9X25_RS10705 ENOG4105S5I Membrane G9X25_RS10710 ENOG4105Q9Y Universal stress protein G9X25_RS10715 ENOG4105DS0 Transcriptional regulator, Crp Fnr family G9X25_RS10720 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) G9X25_RS10725 ENOG4108DG9 Smr protein MutS2 G9X25_RS10730 ENOG4105C8Q Methyl-accepting chemotaxis G9X25_RS10740 ENOG4105C1J atp-dependent rna helicase G9X25_RS10760 ENOG410814C multidrug resistance protein G9X25_RS10765 ENOG4108RW8 Universal stress protein F G9X25_RS10770 ENOG4108RS6 transposase G9X25_RS10775 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) G9X25_RS10785 ENOG4105IKK cytoplasmic protein G9X25_RS10790 ENOG41090X5 Heat shock protein hslJ G9X25_RS10795 ENOG4105C5I Dehydrogenase G9X25_RS10800 ENOG4107H52 Dicarboxylate transport G9X25_RS10805 ENOG410689M (LipO)protein G9X25_RS10810 ENOG4105WXT Conserved Protein G9X25_RS10825 ENOG4105CQ7 ATP-dependent helicase G9X25_RS10830 ENOG4107DB1 DUF218 domain G9X25_RS10835 ENOG4105CPW cytochrome b561 G9X25_RS10840 ENOG4108WF3 methyltransferase G9X25_RS10850 ENOG4105E5Q amino acid AbC transporter G9X25_RS10860 ENOG4105E5Q amino acid AbC transporter G9X25_RS10865 ENOG4107R0W ABC transporter G9X25_RS10875 ENOG4107ZUJ lipid metabolic process G9X25_RS10900 ENOG4105C8Q Methyl-accepting chemotaxis G9X25_RS10905 ENOG4105DDW LysR family Transcriptional regulator G9X25_RS10910 ENOG4105E32 cytoplasmic protein G9X25_RS10915 ENOG4105EBR Carboxylesterase G9X25_RS10925 ENOG4108YYC ycei family G9X25_RS10940 ENOG4108PQ7 sgc region transcriptional regulator G9X25_RS10945 ENOG4108RK0 3-epimerase G9X25_RS10950 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) G9X25_RS10955 ENOG4106P19 photosystem i assembly btpa G9X25_RS10960 ENOG4105DT3 PTS system, galactitol-specific IIc component G9X25_RS10965 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) G9X25_RS10970 ENOG4105CN9 Peptidase m42 family protein G9X25_RS10975 ENOG4108Z9I -acetyltransferase G9X25_RS10980 ENOG4107WE3 acetyltransferase YdcK G9X25_RS10985 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein G9X25_RS10990 ENOG41088CC tellurite resistance protein tehB G9X25_RS10995 ENOG4108KKZ (LipO)protein G9X25_RS11000 ENOG4105DKK Benzoate G9X25_RS11005 ENOG4108JCI Transcriptional regulator G9X25_RS11010 ENOG4105CFP Peptidase U32 G9X25_RS11015 ENOG4105RR0 Protein of unknown function (DUF2554) G9X25_RS11035 ENOG4108UQS dipeptidase G9X25_RS11040 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family G9X25_RS11055 ENOG410654E Membrane G9X25_RS11075 ENOG4105R71 cytoplasmic protein G9X25_RS11085 ENOG4108Z7F N-acetyltransferase G9X25_RS11090 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein G9X25_RS11095 ENOG4108WYP Transcriptional regulator G9X25_RS11100 ENOG4105CHB tonB-dependent Receptor G9X25_RS11105 ENOG4108NS2 receptor G9X25_RS11110 ENOG4105SUV lipoprotein YgdR G9X25_RS11115 ENOG4105C85 amino acid G9X25_RS11125 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase G9X25_RS11130 ENOG4105JAB phenazine biosynthesis protein, phzf family G9X25_RS11135 ENOG4105D0D Nitrate reductase 2, gamma subunit G9X25_RS11140 ENOG4108NZN Respiratory nitrate reductase 2 delta chain G9X25_RS11145 ENOG4108IUE nitrate reductase beta subunit G9X25_RS11150 ENOG4105CRU nitrate reductase, alpha subunit G9X25_RS11155 ENOG4107QND Nitrite extrusion protein G9X25_RS11190 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G9X25_RS11195 ENOG4108MG3 formate dehydrogenase G9X25_RS11200 ENOG4105DQ4 alcohol dehydrogenase G9X25_RS11215 ENOG4105TPS biofilm-dependent modulation protein G9X25_RS11220 ENOG4108Z9K Osmotically inducible protein G9X25_RS11235 ENOG4105XXV Acid-resistance protein G9X25_RS11245 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) G9X25_RS11260 ENOG4105C87 Aminotransferase class I and II G9X25_RS11265 ENOG4105DFD Na H antiporter G9X25_RS11270 ENOG41060NJ transcriptional regulator G9X25_RS11310 ENOG4105MVE transcriptional regulator G9X25_RS11320 ENOG4106UW1 Major Facilitator superfamily G9X25_RS11325 ENOG4105CHW UPF0052 protein G9X25_RS11330 ENOG4108UGV hypoxanthine phosphoribosyltransferase G9X25_RS11355 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) G9X25_RS11380 ENOG4108I5G Major Facilitator superfamily G9X25_RS11385 ENOG4105CPQ Dehydrogenase G9X25_RS11390 ENOG4105C6F GntR Family Transcriptional Regulator G9X25_RS11405 ENOG4105DPX Hydrogenase, large subunit G9X25_RS11410 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit G9X25_RS11430 ENOG4105MVP hydrogenase-1 operon protein HyaF G9X25_RS11450 ENOG4105FFC UPF0187 protein G9X25_RS11455 ENOG4105M0C cytoplasmic protein G9X25_RS11465 ENOG4105C26 Dehydrogenase G9X25_RS11470 ENOG4105EGI Transcriptional regulator G9X25_RS11485 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes G9X25_RS11490 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF G9X25_RS11495 ENOG4106DNR multiple antibiotic resistance protein G9X25_RS11505 ENOG4105E5W Transporter G9X25_RS11515 ENOG4108YDI single-species biofilm formation on inanimate substrate G9X25_RS11520 ENOG4108WTK competence damage-inducible protein G9X25_RS11530 ENOG4105DGW oligopeptidase A G9X25_RS11535 ENOG4105EMU Dehydrogenase G9X25_RS11540 ENOG4107XBN GntR Family Transcriptional Regulator G9X25_RS11545 ENOG41061EV selenium-binding protein YdfZ G9X25_RS11550 ENOG4105DEI Mannitol dehydrogenase G9X25_RS11560 ENOG4105CPQ Dehydrogenase G9X25_RS11580 ENOG4108MK9 spermidine N(1)-acetyltransferase G9X25_RS11590 ENOG4105KBG Protein of unknown function (DUF1161) G9X25_RS11595 ENOG4107QY8 reductase G9X25_RS11600 ENOG4105C3J Cysteine desulfurase G9X25_RS11605 ENOG4105QAX Iron-sulfur G9X25_RS11610 ENOG4107KGK dmso reductase anchor subunit G9X25_RS11615 ENOG4108NEM leader-binding protein dmsD G9X25_RS11620 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component G9X25_RS11625 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system G9X25_RS11630 ENOG4105E90 ABC transporter G9X25_RS11635 ENOG4108IJ8 ABC transporter G9X25_RS11645 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) G9X25_RS11650 ENOG4105DAG ROK family G9X25_RS11655 ENOG4106NZI LysR family Transcriptional regulator G9X25_RS11660 ENOG4105D94 Major Facilitator Superfamily G9X25_RS11670 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap G9X25_RS11685 ENOG4105DSF transport protein G9X25_RS11690 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) G9X25_RS11695 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) G9X25_RS11700 ENOG4105C5D exported protein G9X25_RS11705 ENOG4105D5Q Arginine ornithine antiporter G9X25_RS11710 ENOG4105RA2 Membrane G9X25_RS11715 ENOG4107EXC regulatoR G9X25_RS11720 ENOG4105FCK Membrane G9X25_RS11725 ENOG4105CPN adenine deaminase G9X25_RS11730 ENOG4105JJR Histidine kinase G9X25_RS11740 ENOG4105C9Q fumarate hydratase class II G9X25_RS11745 ENOG4107GFK fumarate G9X25_RS11750 ENOG4105EIP mannose-6-phosphate isomerase G9X25_RS11755 ENOG4106J39 exported protein G9X25_RS11760 ENOG4107P2S Transcriptional regulator G9X25_RS11765 ENOG4105CI1 PTS System G9X25_RS11770 ENOG4105C87 Aminotransferase class I and II G9X25_RS11775 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) G9X25_RS11780 ENOG4105D9R oxidoreductase G9X25_RS11785 ENOG4106C6R beta-lactam resistance protein G9X25_RS11795 ENOG4105M9B inner membrane protein ydgK G9X25_RS11820 ENOG4108UQQ Electron transport complex G9X25_RS11830 ENOG4105CSM endonuclease III G9X25_RS11835 ENOG4105DUX Transporter G9X25_RS11840 ENOG4108K3A Glutathione S-transferase G9X25_RS11860 ENOG410642K Lysozyme inhibitor G9X25_RS11870 ENOG4108XTF Outer Membrane Lipoprotein G9X25_RS11885 ENOG4105Y49 secretion protein, HlyD family G9X25_RS11890 ENOG4105DSW Fusaric acid resistance protein G9X25_RS11895 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) G9X25_RS11900 ENOG4107RGM aldo keto reductase G9X25_RS11905 ENOG4105XZD Fe-S protein G9X25_RS11910 ENOG4108WUH Transcriptional regulator, TetR family G9X25_RS11915 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase G9X25_RS11920 ENOG4108UYE Lactoylglutathione lyase G9X25_RS11930 ENOG4105M2J Glutaredoxin G9X25_RS11935 ENOG4105K4H Nlp p60 protein G9X25_RS11940 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) G9X25_RS11955 ENOG4105F52 Transcriptional regulator G9X25_RS11960 ENOG4105CZQ inner membrane transport protein YdhC G9X25_RS11965 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase G9X25_RS11970 ENOG4108R6K riboflavin synthase, subunit alpha G9X25_RS11990 ENOG4108IUF type iii secretion G9X25_RS11995 ENOG4108TN6 type iii secretion G9X25_RS12000 ENOG41083GP type iii secretion G9X25_RS12005 ENOG4108HHI Type III secretion system protein G9X25_RS12010 ENOG41063Q7 Type III secretion system protein G9X25_RS12025 ENOG4108JIR Flagellum-specific ATP synthase G9X25_RS12035 ENOG4106H1D secretion system apparatus protein G9X25_RS12040 ENOG4105UQF type iii secretion G9X25_RS12045 ENOG4106563 type III secretion system apparatus protein G9X25_RS12095 ENOG4106FZW pathogenicity island effector protein G9X25_RS12100 ENOG4108SZ7 secretion system effector G9X25_RS12110 ENOG4105ZQI secreted protein G9X25_RS12140 ENOG4105BZU Histidine kinase G9X25_RS12150 ENOG4108XDN Transcriptional regulator G9X25_RS12155 ENOG4107SEY Conserved Protein G9X25_RS12160 ENOG4105RFR Protein of unknown function (DUF2767) G9X25_RS12165 ENOG4108ZXC Two component transcriptional regulator, luxr family G9X25_RS12170 ENOG4106AFQ Histidine kinase G9X25_RS12175 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G9X25_RS12180 ENOG4106WHD Tetrathionate reductase G9X25_RS12185 ENOG4105DB1 molybdopterin oxidoreductase G9X25_RS12190 ENOG4108RVA ribokinase G9X25_RS12200 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) G9X25_RS12205 ENOG4105CUB amino acid G9X25_RS12210 ENOG4105CA9 Pyruvate kinase G9X25_RS12225 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein G9X25_RS12240 ENOG4105JRK feS assembly protein SufD G9X25_RS12245 ENOG4105C3K feS assembly ATPase SufC G9X25_RS12250 ENOG4105DIW FeS assembly protein SUFB G9X25_RS12255 ENOG4108Z4V iron-sulfur cluster assembly G9X25_RS12260 ENOG4108ETY sodium dicarboxylate symporter G9X25_RS12265 ENOG410671Z uncharacterized protein ydiH G9X25_RS12270 ENOG4105KA0 thioesterase Superfamily protein G9X25_RS12275 ENOG4105CQB FAD linked oxidase domain protein G9X25_RS12280 ENOG4105IPI Membrane G9X25_RS12290 ENOG4105SUA Ydil protein G9X25_RS12295 ENOG4105EMV Major Facilitator G9X25_RS12300 ENOG4105EMV Major Facilitator G9X25_RS12315 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) G9X25_RS12320 ENOG4105C1G acyl-Coa dehydrogenase G9X25_RS12325 ENOG4105W4W Transcriptional regulator G9X25_RS12330 ENOG4105CV7 Electron transfer flavoprotein G9X25_RS12335 ENOG4105C10 Electron transfer flavoprotein G9X25_RS12340 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase G9X25_RS12345 ENOG41090P5 ferredoxin-like protein G9X25_RS12350 ENOG4105CEY Amp-dependent synthetase and ligase G9X25_RS12355 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) G9X25_RS12365 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) G9X25_RS12385 ENOG4108QBX (LipO)protein G9X25_RS12395 ENOG4108V06 Glutathione peroxidase G9X25_RS12410 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) G9X25_RS12460 ENOG4105DFE Dna adenine methylase G9X25_RS12465 ENOG4105VZ1 Replication Protein G9X25_RS12485 ENOG4105ED4 portal protein G9X25_RS12530 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 G9X25_RS12570 ENOG4105UZW Tail fiber assembly protein G9X25_RS12575 ENOG4105H38 Membrane G9X25_RS12580 ENOG4105UZW Tail fiber assembly protein G9X25_RS12625 ENOG41060TC Hok gef cell toxic protein G9X25_RS12640 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) G9X25_RS12645 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) G9X25_RS12665 ENOG41082NX 50s ribosomal protein l35 G9X25_RS12670 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) G9X25_RS12695 ENOG4108NE3 Salt-induced outer membrane protein G9X25_RS12700 ENOG4105DE4 1-phosphofructokinase G9X25_RS12705 ENOG4105P10 Uncharacterized protein ydiZ G9X25_RS12715 ENOG4107PN8 YfeABCD locus regulator G9X25_RS12720 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 G9X25_RS12725 ENOG4107K5X Membrane-bound metal-dependent hydrolase G9X25_RS12730 ENOG4108ETY sodium dicarboxylate symporter G9X25_RS12740 ENOG4105CH6 catalase G9X25_RS12750 ENOG4105F8D glycoside hydrolase family 4 G9X25_RS12755 ENOG4105EZV Transcriptional regulator G9X25_RS12760 ENOG4105VCP PTS System G9X25_RS12765 ENOG4105CK1 PTS System G9X25_RS12770 ENOG4105VZJ PTS System G9X25_RS12775 ENOG4105KKI DNA-binding transcriptional activator OsmE G9X25_RS12785 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) G9X25_RS12790 ENOG4108SPG Periplasmic Protein G9X25_RS12795 ENOG4107UI5 Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity) G9X25_RS12820 ENOG4105CGK Exodeoxyribonuclease III G9X25_RS12825 ENOG4105M6F mutator MutT protein G9X25_RS12830 ENOG4105MTM Protein of unknown function (DUF1496) G9X25_RS12835 ENOG4105D82 Glutamate dehydrogenase G9X25_RS12840 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) G9X25_RS12845 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) G9X25_RS12850 ENOG41069NU Nitroreductase G9X25_RS12855 ENOG4105D07 Signal peptide peptidase, SppA G9X25_RS12860 ENOG4105HDK L-asparaginase G9X25_RS12865 ENOG4108RWI nicotinamidase G9X25_RS12870 ENOG4108KUU Inner membrane metabolite transport protein ydjE G9X25_RS12875 ENOG4105E98 transcriptional regulator DeoR family G9X25_RS12880 ENOG4105CPC Aldo Keto reductase G9X25_RS12885 ENOG4107UH8 sugar kinase G9X25_RS12890 ENOG4105D2N Aldolase G9X25_RS12895 ENOG4105CPQ Dehydrogenase G9X25_RS12900 ENOG4107TE1 transport protein G9X25_RS12905 ENOG4105CPQ Dehydrogenase G9X25_RS12915 ENOG4105VUT cytoplasmic protein G9X25_RS12925 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase G9X25_RS12930 ENOG4105DSB aldose 1-epimerase G9X25_RS12935 ENOG4105CV8 reductase G9X25_RS12940 ENOG4105C4X radical SAM domain protein G9X25_RS12945 ENOG4105GNX MltA-interacting MipA family protein G9X25_RS12950 ENOG4105CYN Serine protein kinase G9X25_RS12965 ENOG4108KHP Diguanylate cyclase G9X25_RS12970 ENOG4108KXH Ybak prolyl-tRNA synthetase associated G9X25_RS12985 ENOG4105R1U AraC Family Transcriptional Regulator G9X25_RS12990 ENOG4105DJ2 Major Facilitator Superfamily G9X25_RS12995 ENOG4105K78 MarR family Transcriptional regulator G9X25_RS13005 ENOG4105UCG Domain of unknown function (DUF333) G9X25_RS13010 ENOG4106G4W G9X25_RS13015 ENOG4105Y3U Transglycosylase-associated protein G9X25_RS13025 ENOG4105YP6 Domain of unknown function (DUF1869) G9X25_RS13030 ENOG4108YS1 cytoplasmic protein G9X25_RS13040 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) G9X25_RS13050 ENOG4108Z6Z Transcriptional regulator G9X25_RS13065 ENOG4108MEK Metal-binding protein YodA G9X25_RS13080 ENOG4105D64 Mechanosensitive ion channel G9X25_RS13085 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) G9X25_RS13090 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) G9X25_RS13115 ENOG4108VKM cytochrome b561 G9X25_RS13125 ENOG4108ZNX Heat shock protein G9X25_RS13145 ENOG4105H38 Membrane G9X25_RS13155 ENOG41060EU Cold shock-like protein G9X25_RS13160 ENOG4106F2Y RICIN G9X25_RS13165 ENOG4105Y50 Virulence Protein G9X25_RS13175 ENOG4108TMH cytolethal distending toxin G9X25_RS13205 ENOG4108HMX isocitrate dehydrogenase (NADP) G9X25_RS13210 ENOG4108R99 pseudouridine synthase G9X25_RS13235 ENOG4107QTF adenylosuccinate lyase G9X25_RS13250 ENOG4105EZE Cupin 4 family protein G9X25_RS13280 ENOG4105D38 putrescine abc transporter G9X25_RS13285 ENOG4108HM4 ABC transporter G9X25_RS13290 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) G9X25_RS13300 ENOG4105D60 lipoprotein releasing system transmembrane protein G9X25_RS13305 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) G9X25_RS13310 ENOG4105D60 lipoprotein releasing system transmembrane protein G9X25_RS13315 ENOG4108JA2 transcriptioN-repair coupling factor G9X25_RS13320 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein G9X25_RS13325 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction G9X25_RS13330 ENOG4108IND Tetr family transcriptional regulator G9X25_RS13340 ENOG4107MBR 17 kDa surface antigen G9X25_RS13345 ENOG4105CEP NADH dehydrogenase G9X25_RS13365 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) G9X25_RS13370 ENOG41090DQ Lipoprotein G9X25_RS13375 ENOG4105K59 histidine triad (HIT) protein G9X25_RS13380 ENOG4105CNM Receptor G9X25_RS13385 ENOG4105CI1 PTS System G9X25_RS13390 ENOG4105F8V Hydrolase, tatD family G9X25_RS13395 ENOG4107QRG dna polymerase iii G9X25_RS13405 ENOG4105HHA aminodeoxychorismate lyase G9X25_RS13410 ENOG4105YAZ 4-amino-4-deoxychorismate lyase G9X25_RS13420 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) G9X25_RS13425 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) G9X25_RS13430 ENOG4105CHR reductase G9X25_RS13435 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase G9X25_RS13455 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein G9X25_RS13465 ENOG4105EI2 Pseudouridine synthase G9X25_RS13470 ENOG4107QQB Ribonuclease E G9X25_RS13475 ENOG4105DTJ flagellar hook-associated protein G9X25_RS13480 ENOG4105E1Q flagellar hook-associated protein G9X25_RS13485 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj G9X25_RS13500 ENOG4105CGA flagellar basal-body rod protein FlgG G9X25_RS13505 ENOG4108KPB Flagellar basal-body rod protein FlgF G9X25_RS13510 ENOG4105BZE flagellar hook protein, FlgE G9X25_RS13515 ENOG4105W00 Flagellar hook capping protein G9X25_RS13520 ENOG4108ZC9 flagellar basal-body rod protein flgc G9X25_RS13525 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) G9X25_RS13530 ENOG4105CKS Flagella basal body P-ring formation protein flgA G9X25_RS13535 ENOG4105M9M anti-sigma28 factor FlgM G9X25_RS13540 ENOG4105QVD Flagella synthesis protein FlgN G9X25_RS13545 ENOG4105CJR Integral membrane protein (MviN G9X25_RS13550 ENOG4105EP9 oxidoreductase G9X25_RS13560 ENOG4105D9U N-acetyltransferase G9X25_RS13570 ENOG4105E9S glutaredoxin 2 G9X25_RS13575 ENOG4105F3T (LipO)protein G9X25_RS13585 ENOG4105MEA DNA damage-inducible protein i G9X25_RS13590 ENOG4105PVA Biofilm formation regulatory protein BssS G9X25_RS13605 ENOG4105DS1 cytochrome b561 G9X25_RS13610 ENOG4108YYC ycei family G9X25_RS13620 ENOG4105D1S lipid A biosynthesis G9X25_RS13630 ENOG4108W47 Acidic protein msyB G9X25_RS13635 ENOG4105NAC (LipO)protein G9X25_RS13640 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) G9X25_RS13655 ENOG4107RZC phospholipase d G9X25_RS13665 ENOG41068SS G9X25_RS13670 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) G9X25_RS13675 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin G9X25_RS13680 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers G9X25_RS13685 ENOG41086KC Transcriptional regulator G9X25_RS13690 ENOG4108XDW curli assembly protein CsgE G9X25_RS13695 ENOG4108WYR Curli production assembly transport component, CsgF G9X25_RS13700 ENOG4105P8Q Curli production assembly transport component CsgG G9X25_RS13705 ENOG4108UQ5 membrane protein YcdZ G9X25_RS13710 ENOG4107XHZ cytoplasmic chaperone TorD family protein G9X25_RS13735 ENOG4107RJ5 oxidoreductase G9X25_RS13740 ENOG4105JHE Major Facilitator Superfamily G9X25_RS13745 ENOG4108QGT oligogalacturonate-specific porin G9X25_RS13755 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) G9X25_RS13760 ENOG4107RJ1 sodium solute G9X25_RS13765 ENOG4105QEK Transcriptional regulator G9X25_RS13770 ENOG4105D5M phosphate starvation-inducible protein G9X25_RS13775 ENOG4105CK7 Sodium proline symporter G9X25_RS13790 ENOG4108R86 Transcriptional regulator G9X25_RS13795 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 G9X25_RS13800 ENOG4105CS1 NAD(P)H quinone oxidoreductase G9X25_RS13805 ENOG4105XH3 G9X25_RS13810 ENOG4105D6F Phosphatase G9X25_RS13815 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen G9X25_RS13820 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) G9X25_RS13825 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) G9X25_RS13880 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase G9X25_RS13885 ENOG4105C26 Dehydrogenase G9X25_RS13895 ENOG4108V8F Transcriptional regulator, MarR family G9X25_RS13900 ENOG4105EFA 4-hydroxyphenylacetate G9X25_RS13905 ENOG4107UWN reductase G9X25_RS13910 ENOG4105VT2 5-hydroxyisourate hydrolase G9X25_RS13915 ENOG4105CK6 Two component transcriptional regulator (Winged helix family G9X25_RS13920 ENOG4107ZY3 Histidine kinase G9X25_RS13935 ENOG4106YSC G9X25_RS13940 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell G9X25_RS13945 ENOG4106HNN Invasion protein G9X25_RS13950 ENOG41084BJ Pentapeptide repeat protein G9X25_RS13985 ENOG4105UZW Tail fiber assembly protein G9X25_RS13990 ENOG410685N tail fiber protein G9X25_RS14080 ENOG4105M6F mutator MutT protein G9X25_RS14115 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 G9X25_RS14120 ENOG4105KUS lysozyme G9X25_RS14140 ENOG4105RWQ Protein of unknown function (DUF1364) G9X25_RS14175 ENOG4105CDU Replicative dna helicase G9X25_RS14200 ENOG41087BU transcriptional repressor DicA G9X25_RS14215 ENOG41076J9 exonuclease VIII G9X25_RS14245 ENOG4108MN8 Membrane G9X25_RS14255 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 G9X25_RS14265 ENOG4108V1U phospholipid-binding protein G9X25_RS14280 ENOG4105K4P CoA-binding domain protein G9X25_RS14290 ENOG4108Z5K methylglyoxal synthase G9X25_RS14295 ENOG41088T4 Helicase IV G9X25_RS14300 ENOG410901E Membrane G9X25_RS14305 ENOG4105EM2 membrane G9X25_RS14310 ENOG4108RZ1 DNA transformation protein G9X25_RS14320 ENOG4105UYK outer membrane protein a G9X25_RS14330 ENOG4105DAN ATP-dependent protease G9X25_RS14340 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) G9X25_RS14345 ENOG4108Q2G (LipO)protein G9X25_RS14350 ENOG4105DY2 Paraquat-inducible protein b G9X25_RS14355 ENOG4105F1S paraquat-inducible protein a G9X25_RS14360 ENOG4105C5H ABC transporter G9X25_RS14370 ENOG4105QVC MOSC domain-containing protein G9X25_RS14375 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) G9X25_RS14385 ENOG4105CD8 aminopeptidase N G9X25_RS14410 ENOG4105C5S asparaginyl-tRNA synthetase G9X25_RS14415 ENOG4105FCK Membrane G9X25_RS14420 ENOG4105CGF Aromatic amino acid aminotransferase G9X25_RS14425 ENOG4105C5X domain protein G9X25_RS14430 ENOG4105EAQ (twin-arginine translocation) pathway signal G9X25_RS14435 ENOG4105DIT ErfK YbiS YcfS YnhG family protein G9X25_RS14445 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) G9X25_RS14455 ENOG4106371 Methyltransferase G9X25_RS14460 ENOG4107S90 membrAne G9X25_RS14465 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups G9X25_RS14480 ENOG4105T0Z Conserved Protein G9X25_RS14490 ENOG4105BZ1 (ABC) transporter G9X25_RS14495 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 G9X25_RS14500 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) G9X25_RS14505 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) G9X25_RS14515 ENOG4108K0D peptidase, M48 G9X25_RS14520 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase G9X25_RS14530 ENOG4107VMU Membrane G9X25_RS14535 ENOG4105DDY UPF0142 protein ycaO G9X25_RS14540 ENOG4105TMB Formate nitrite transporter G9X25_RS14545 ENOG4105C6N Formate acetyltransferase G9X25_RS14550 ENOG4105GUS G9X25_RS14555 ENOG4105F1A Pyruvate formate-lyase G9X25_RS14560 ENOG4105E5D amino acid G9X25_RS14570 ENOG4107KGK dmso reductase anchor subunit G9X25_RS14575 ENOG4105QAX Iron-sulfur G9X25_RS14580 ENOG4107QY8 reductase G9X25_RS14590 ENOG4105D1H recombination factor protein RarA G9X25_RS14600 ENOG4105CNU cell division protein FtsK G9X25_RS14605 ENOG4105EW9 transcriptional regulator AsnC family G9X25_RS14610 ENOG4105C3M thioredoxin reductase G9X25_RS14615 ENOG4108JJ9 ABC, transporter G9X25_RS14620 ENOG4108JJ8 (ABC) transporter G9X25_RS14635 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) G9X25_RS14640 ENOG4105HEI LysR family (Transcriptional regulator G9X25_RS14645 ENOG4105EUB pirin domain protein G9X25_RS14650 ENOG4105CHJ isochorismatase hydrolase G9X25_RS14660 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit G9X25_RS14670 ENOG4105VEQ Cold shock protein G9X25_RS14675 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) G9X25_RS14680 ENOG4105DJY efflux transporter, rnd family, mfp subunit G9X25_RS14685 ENOG4108MJ5 VirK protein G9X25_RS14690 ENOG4105CPB ATP-dependent endonuclease of the OLD family G9X25_RS14695 ENOG4105DWU Membrane G9X25_RS14705 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) G9X25_RS14710 ENOG4105C7K acetolactate synthase G9X25_RS14715 ENOG4105C5W Aldolase G9X25_RS14720 ENOG4105CGD Nad-dependent epimerase dehydratase G9X25_RS14725 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase G9X25_RS14730 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase G9X25_RS14740 ENOG41064MM (LipO)protein G9X25_RS14745 ENOG4105E5Z arginine transporter ATP-binding subunit G9X25_RS14750 ENOG4106PMH Extracellular solute-binding protein family 3 G9X25_RS14755 ENOG4105GBT ABC transporter G9X25_RS14760 ENOG4105DMR ABC, transporter G9X25_RS14765 ENOG4106TNF Periplasmic binding protein G9X25_RS14790 ENOG4105RBQ inner membrane protein ybjO G9X25_RS14795 ENOG4105D38 putrescine abc transporter G9X25_RS14800 ENOG4105F38 ABC transporter, permease G9X25_RS14805 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) G9X25_RS14810 ENOG4107RUE extracellular solute-binding protein family 1 G9X25_RS14815 ENOG4108RMJ sensory transduction regulator G9X25_RS14825 ENOG4108DBC nitroreductase G9X25_RS14830 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress G9X25_RS14835 ENOG41090BQ Glutaredoxin G9X25_RS14840 ENOG4105GWF inner membrane protein YbjM G9X25_RS14850 ENOG4108RFG Tetr family transcriptional regulator G9X25_RS14855 ENOG4106UW1 Major Facilitator superfamily G9X25_RS14860 ENOG4108HCJ Hydrolase G9X25_RS14865 ENOG4107QF7 multi-drug G9X25_RS14870 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase G9X25_RS14875 ENOG4107FB0 transcriptional regulator DeoR family G9X25_RS14880 ENOG4105DZ1 carboxypeptidase G9X25_RS14885 ENOG4108TGY Glutathione S-transferase G9X25_RS14890 ENOG4105D8V Glucose sorbosone dehydrogenase G9X25_RS14895 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway G9X25_RS14915 ENOG4105DEF Extracellular solute-binding protein, family 5 G9X25_RS14920 ENOG4108JQ6 ABC transporter G9X25_RS14925 ENOG4105D44 asparaginase G9X25_RS14930 ENOG4105CVM Molybdenum cofactor synthesis domain protein G9X25_RS14935 ENOG4105D06 uba thif-type nad fad binding protein G9X25_RS14940 ENOG4105F1A Pyruvate formate-lyase G9X25_RS14950 ENOG4108HCJ Hydrolase G9X25_RS14955 ENOG41072TH Protein of unknown function (DUF1479) G9X25_RS14960 ENOG4105C5H ABC transporter G9X25_RS14965 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein G9X25_RS14970 ENOG4105F4P )-transporter G9X25_RS14975 ENOG4105KST dependent repressor G9X25_RS14985 ENOG4108I6E Sulfatase G9X25_RS14990 ENOG4108T1M outer membrane protein x G9X25_RS15005 ENOG4107R0W ABC transporter G9X25_RS15010 ENOG4105E5Q amino acid AbC transporter G9X25_RS15015 ENOG4105CDA abc transporter atp-binding protein G9X25_RS15020 ENOG4105D8X mechanosensitive ion channel G9X25_RS15030 ENOG4105KSC Transcriptional regulator, TraR DksA family G9X25_RS15035 ENOG4105VR4 UPF0379 protein ybiJ G9X25_RS15040 ENOG4108MTB glycosyl transferase family G9X25_RS15045 ENOG4105DVT helicase G9X25_RS15050 ENOG4105C1J atp-dependent rna helicase G9X25_RS15055 ENOG4107MVR Transcriptional regulator G9X25_RS15065 ENOG4105CJ1 ABC, transporter G9X25_RS15070 ENOG4107QWP ABC-2 type transporter G9X25_RS15075 ENOG4107QWP ABC-2 type transporter G9X25_RS15080 ENOG4105I9U inner membrane protein ybhQ G9X25_RS15085 ENOG4105X23 Endonuclease Exonuclease phosphatase G9X25_RS15090 ENOG4105DZQ phospholipase D Transphosphatidylase G9X25_RS15095 ENOG4107UXM Membrane G9X25_RS15115 ENOG4105HFZ Membrane G9X25_RS15120 ENOG4108ZAF Molybdopterin G9X25_RS15125 ENOG4105M00 molybdopterin converting factor, subunit 1 G9X25_RS15135 ENOG4108RIR Molybdenum cofactor biosynthesis protein G9X25_RS15145 ENOG4105CHW UPF0052 protein G9X25_RS15165 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) G9X25_RS15170 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) G9X25_RS15185 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) G9X25_RS15190 ENOG4108V1U phospholipid-binding protein G9X25_RS15215 ENOG4105CI2 imidazolone-5-propionate hydrolase G9X25_RS15220 ENOG4105NBR Pectinesterase G9X25_RS15230 ENOG4108K4B hydrolase G9X25_RS15240 ENOG4105E0C molybdate abc transporter G9X25_RS15245 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein G9X25_RS15250 ENOG4108RS6 transposase G9X25_RS15260 ENOG4105F4R Transcriptional regulator mode G9X25_RS15265 ENOG4105DKW ABC transporter G9X25_RS15275 ENOG4105CMR udp-glucose 4-epimerase G9X25_RS15280 ENOG4105F0Z galactose-1-phosphate uridylyltransferase G9X25_RS15290 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) G9X25_RS15300 ENOG4105E0A ABC, transporter G9X25_RS15305 ENOG4105EHG Permease protein G9X25_RS15310 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) G9X25_RS15315 ENOG4105JND homeobox protein G9X25_RS15320 ENOG4105PGM cation diffusion facilitator family transporter G9X25_RS15325 ENOG4106Z1T Nicotinamide Mononucleotide Transporter G9X25_RS15360 ENOG4105UFD tol-pal system protein YbgF G9X25_RS15365 ENOG4105KCK Peptidoglycan-associated lipoprotein G9X25_RS15385 ENOG4105E02 MotA TolQ exbB proton channel G9X25_RS15390 ENOG4107YD3 Thioesterase G9X25_RS15395 ENOG4105KJB cyd operon protein YbgE G9X25_RS15405 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii G9X25_RS15410 ENOG4105C4M (Ubiquinol oxidase) subunit I G9X25_RS15415 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha G9X25_RS15425 ENOG4105C7S Dehydrogenase G9X25_RS15430 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 G9X25_RS15435 ENOG4105E33 succinate dehydrogenase G9X25_RS15440 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) G9X25_RS15445 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein G9X25_RS15450 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit G9X25_RS15460 ENOG4105BZN citrate synthase G9X25_RS15465 ENOG4108KK1 membrane protein AbrB duplication G9X25_RS15530 ENOG4108W9T type 1 fimbriae regulatory protein G9X25_RS15545 ENOG4107R7A Allophanate hydrolase subunit 2 G9X25_RS15550 ENOG4105P4J Allophanate hydrolase, subunit 1 G9X25_RS15555 ENOG4107QNR UPF0135 protein G9X25_RS15565 ENOG4105CVP deoxyribo-dipyrimidine photolyase G9X25_RS15570 ENOG4105XIQ Protein of unknown function (DUF2517) G9X25_RS15595 ENOG4105C08 Histidine kinase G9X25_RS15600 ENOG4105EEX Two component transcriptional regulator (Winged helix family G9X25_RS15610 ENOG4105CXN decarboxylase G9X25_RS15615 ENOG4105D5Q Arginine ornithine antiporter G9X25_RS15625 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 G9X25_RS15630 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) G9X25_RS15635 ENOG4105EV9 Alpha Beta Hydrolase G9X25_RS15640 ENOG4105NNH LexA regulated protein G9X25_RS15645 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) G9X25_RS15650 ENOG41090R7 Ferric uptake G9X25_RS15655 ENOG4106P55 Transcriptional regulator G9X25_RS15660 ENOG4107EFR Flavocytochrome c G9X25_RS15665 ENOG41079YP Citrate utilization protein b G9X25_RS15670 ENOG4105CSH Transporter G9X25_RS15675 ENOG4105GX6 (LipO)protein G9X25_RS15680 ENOG4105J5J Outer membrane porin G9X25_RS15690 ENOG4105CI1 PTS System G9X25_RS15700 ENOG4105CE4 GlcNAc 6-P deacetylase G9X25_RS15705 ENOG4105E2R ROK family G9X25_RS15710 ENOG4105D4U had-superfamily hydrolase, subfamily iia G9X25_RS15715 ENOG4105CAQ asparagine synthetase G9X25_RS15755 ENOG4108RS6 transposase G9X25_RS15765 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family G9X25_RS15775 ENOG4105C9A Phoh family G9X25_RS15785 ENOG4108JU5 Magnesium and cobalt efflux protein G9X25_RS15790 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) G9X25_RS15795 ENOG4107RP9 extracellular solute-binding protein, family 3 G9X25_RS15800 ENOG4105EAD ABC transporter G9X25_RS15805 ENOG4105DRP amino acid AbC transporter G9X25_RS15810 ENOG4105CDA abc transporter atp-binding protein G9X25_RS15820 ENOG4107PAI alpha helical protein G9X25_RS15825 ENOG4108JUB Transcriptional regulator G9X25_RS15830 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) G9X25_RS15855 ENOG4105DJF DNA polymerase III, delta' subunit G9X25_RS15860 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) G9X25_RS15865 ENOG4107QZB decarboxylase G9X25_RS15870 ENOG4108TGR phosphatase G9X25_RS15875 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) G9X25_RS15880 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) G9X25_RS15885 ENOG4105CJN penicillin-binding protein G9X25_RS15890 ENOG4105CNI cell division protein FtsW G9X25_RS15895 ENOG4105K6T rare lipoprotein A G9X25_RS15900 ENOG4105DZ1 carboxypeptidase G9X25_RS15905 ENOG4108Z43 UPF0250 protein G9X25_RS15915 ENOG41064T2 transcriptional regulator, lysR family G9X25_RS15935 ENOG4107Z6W Protein CrcB homolog G9X25_RS15950 ENOG4105CEE C4-dicarboxylate transporter G9X25_RS15955 ENOG4106YYS transcriptional regulatory protein G9X25_RS15960 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism G9X25_RS15965 ENOG4105DUA (citrate (pro-3S)-lyase ligase G9X25_RS15970 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) G9X25_RS15975 ENOG4105CI0 Citrate lyase G9X25_RS15980 ENOG4105CHY citrate lyase, alpha G9X25_RS15985 ENOG4105YGP holo-ACP synthase CitX G9X25_RS15990 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase G9X25_RS15995 ENOG4107QPK )-transporter G9X25_RS16000 ENOG4105KTS ribonuclease G9X25_RS16005 ENOG4105NXH GreA GreB family elongation factor G9X25_RS16010 ENOG4105E2A Dehydrogenase G9X25_RS16015 ENOG4108U51 Universal stress protein G9X25_RS16025 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G9X25_RS16030 ENOG4107QY8 reductase G9X25_RS16040 ENOG4108JU3 Alkyl hydroperoxide reductase G9X25_RS16045 ENOG4105D3R alkyl hydroperoxide reductase G9X25_RS16050 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase G9X25_RS16055 ENOG4105DQS Transcriptional regulator G9X25_RS16060 ENOG4105BZV Phosphoadenosine phosphosulfate reductase G9X25_RS16065 ENOG4105GTN ParB Domain Protein Nuclease G9X25_RS16070 ENOG4105CHM Aminotransferase G9X25_RS16075 ENOG4107SCQ Iron-containing alcohol dehydrogenase G9X25_RS16080 ENOG4105VCD cytoplasmic protein G9X25_RS16085 ENOG4105D22 carbon starvation protein G9X25_RS16095 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase G9X25_RS16100 ENOG4105WQI isochorismatase G9X25_RS16105 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase G9X25_RS16110 ENOG4105E4F Isochorismate synthase G9X25_RS16115 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein G9X25_RS16120 ENOG4105E8G Major facilitator Superfamily G9X25_RS16125 ENOG4105DQ5 transport system permease protein G9X25_RS16130 ENOG4105TVJ transport system, permease G9X25_RS16135 ENOG4105E0A ABC, transporter G9X25_RS16140 ENOG4108QY5 Ferric enterobactin transport protein G9X25_RS16145 ENOG4105C0W non-ribosomal peptide synthetase G9X25_RS16150 ENOG41085A6 mbth domain-containing protein G9X25_RS16155 ENOG4105E93 esterase G9X25_RS16160 ENOG4107RNH Outer membrane receptor FepA G9X25_RS16165 ENOG4108TSE Transferase G9X25_RS16175 ENOG4105WQ6 Membrane G9X25_RS16180 ENOG4105HFT AraC family transcriptional regulator G9X25_RS16185 ENOG41067SE Tetr family transcriptional regulator G9X25_RS16190 ENOG4105MSB protein, conserved in bacteria G9X25_RS16195 ENOG4108RCM Nitroreductase G9X25_RS16205 ENOG4105CUY Mechanosensitive ion channel G9X25_RS16210 ENOG4105C85 amino acid G9X25_RS16220 ENOG4108KBJ Inner membrane protein YkgB G9X25_RS16225 ENOG41066GK UPF0379 protein ykgI G9X25_RS16230 ENOG4107QN2 dihydrolipoyl dehydrogenase G9X25_RS16235 ENOG4108K01 transcriptional regulator G9X25_RS16255 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) G9X25_RS16260 ENOG4105CKK Glycosyl transferase, family 2 G9X25_RS16280 ENOG4106KCD HTH_LUXR G9X25_RS16290 ENOG4106721 fimbriae Y protein G9X25_RS16295 ENOG4108Q9V regulatoR G9X25_RS16300 ENOG4108ZI2 Fimbrial protein G9X25_RS16305 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) G9X25_RS16310 ENOG4105CW0 outer membrane usher protein G9X25_RS16315 ENOG4108AF8 Chaperone G9X25_RS16325 ENOG4108WDE Fimbrial protein G9X25_RS16335 ENOG4105WQ3 Rna-binding protein G9X25_RS16340 ENOG4105S2T inner membrane protein YbcI G9X25_RS16360 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) G9X25_RS16370 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) G9X25_RS16375 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit G9X25_RS16380 ENOG4105C5B carbamate kinase G9X25_RS16385 ENOG4105G5A Protein of unknown function (DUF2877) G9X25_RS16390 ENOG4107REC cytoplasmic protein G9X25_RS16395 ENOG4107R1Q Membrane protein FdrA G9X25_RS16400 ENOG4105DG4 malate L-lactate dehydrogenase G9X25_RS16405 ENOG4105CE7 Amidase, hydantoinase carbamoylase family G9X25_RS16410 ENOG4105S0E allantoin catabolism protein G9X25_RS16415 ENOG4105BZW Glycerate kinase G9X25_RS16430 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease G9X25_RS16440 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase G9X25_RS16445 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) G9X25_RS16450 ENOG41060W2 glyoxylate carboligase G9X25_RS16475 ENOG4108UMI ABC transporter, permease G9X25_RS16480 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) G9X25_RS16485 ENOG4105D01 (LipO)protein G9X25_RS16495 ENOG4105CV6 ABC transporter, permease G9X25_RS16500 ENOG4108I0Y (ABC) transporter G9X25_RS16505 ENOG4108UJV acyl-CoA thioesterase i G9X25_RS16510 ENOG4105E1F short-chain dehydrogenase reductase G9X25_RS16515 ENOG4107QR8 Thioredoxin G9X25_RS16520 ENOG4105C4B ABC transporter, permease G9X25_RS16525 ENOG41083J0 (ABC) transporter G9X25_RS16530 ENOG4107QX8 SPFH domain, Band 7 family protein G9X25_RS16535 ENOG4105G5H Membrane G9X25_RS16540 ENOG4108Z6Z Transcriptional regulator G9X25_RS16545 ENOG4105C59 p-type ATPase G9X25_RS16555 ENOG4105MBR gumn family G9X25_RS16560 ENOG4108Z66 YbaK ebsC protein G9X25_RS16565 ENOG4105CGH 5'-nucleotidase G9X25_RS16570 ENOG4105EU0 Major facilitator Superfamily G9X25_RS16575 ENOG4105CKD glutathione-regulated potassium-efflux system protein G9X25_RS16580 ENOG4107RE1 Inosine-guanosine kinase G9X25_RS16585 ENOG4105F2M alpha beta hydrolase fold-3 domain protein G9X25_RS16615 ENOG4107QMP dna polymerase iii subunits gamma and tau G9X25_RS16625 ENOG4105WD1 Membrane G9X25_RS16630 ENOG4108URS primosomal replication protein n'' G9X25_RS16635 ENOG4106428 Protein of unknown function (DUF2496) G9X25_RS16640 ENOG4105DNE Transposase G9X25_RS16645 ENOG4105EGS Mechanosensitive ion channel G9X25_RS16650 ENOG4107XI7 Tetr family transcriptional regulator G9X25_RS16655 ENOG4105C1P efflux transporter, rnd family, mfp subunit G9X25_RS16660 ENOG4105BZS acriflavin resistance protein G9X25_RS16665 ENOG4108UKR Biofilm formation regulator YbaJ G9X25_RS16675 ENOG4108UW5 maltose o-acetyltransferase G9X25_RS16680 ENOG4105GSJ Inner membrane protein ylaC G9X25_RS16695 ENOG41066DG (EAL) domain protein G9X25_RS16705 ENOG41080UX Methyltransferase G9X25_RS16710 ENOG4108MNP Glycoprotein polysaccharide metabolism G9X25_RS16715 ENOG4105C29 acyl-CoA thioesterase G9X25_RS16720 ENOG4105BZU Histidine kinase G9X25_RS16725 ENOG4108YZA Nitrogen regulatory protein pii G9X25_RS16730 ENOG4105BZ1 (ABC) transporter G9X25_RS16735 ENOG4105BZ1 (ABC) transporter G9X25_RS16740 ENOG4108XM1 transcriptional regulator AsnC family G9X25_RS16750 ENOG4108AZI Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity) G9X25_RS16755 ENOG4108NFA extracellular solute-binding protein G9X25_RS16765 ENOG4108TGP Thioesterase superfamily protein G9X25_RS16770 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein G9X25_RS16775 ENOG4105EIN peptidylprolyl cis-trans isomerase G9X25_RS16780 ENOG4105K70 DNA-binding protein G9X25_RS16785 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) G9X25_RS16805 ENOG4105M85 Bola protein G9X25_RS16810 ENOG4105IEY (LipO)protein G9X25_RS16815 ENOG4105EYM Major Facilitator superfamily G9X25_RS16820 ENOG4105E2S oxidase) subunit II G9X25_RS16825 ENOG4105BZ9 Cytochrome C oxidase, subunit I G9X25_RS16830 ENOG4105CCU oxidase (Subunit III) G9X25_RS16835 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) G9X25_RS16845 ENOG4107RDB Major Facilitator G9X25_RS16855 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) G9X25_RS16860 ENOG4107S0N DJ-1 family G9X25_RS16870 ENOG4105QAX Iron-sulfur G9X25_RS16875 ENOG4108J2R molybdopterin oxidoreductase G9X25_RS16890 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) G9X25_RS16895 ENOG4105CTB Polyprenyl synthetase G9X25_RS16905 ENOG4105CPC Aldo Keto reductase G9X25_RS16910 ENOG4108ZAI phosphatidylglycerophosphatase a G9X25_RS16915 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) G9X25_RS16920 ENOG4107YIM Involved in the transcription termination process (By similarity) G9X25_RS16930 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) G9X25_RS16940 ENOG4108KIC (LipO)protein G9X25_RS16945 ENOG4105DRB nucleoside-specific channel-forming protein G9X25_RS16965 ENOG4105N1F Hnh endonuclease G9X25_RS16980 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) G9X25_RS16990 ENOG4105VIE preprotein translocase, subunit YajC G9X25_RS17010 ENOG4105D3R alkyl hydroperoxide reductase G9X25_RS17015 ENOG4107R28 alpha amylase, catalytic region G9X25_RS17020 ENOG4105C85 amino acid G9X25_RS17025 ENOG4105CWM branched-chain amino acid transport system II carrier protein G9X25_RS17030 ENOG4105BZU Histidine kinase G9X25_RS17035 ENOG4105CK6 Two component transcriptional regulator (Winged helix family G9X25_RS17040 ENOG4107RH8 nuclease SbcCD subunit D G9X25_RS17045 ENOG4105EYH Exonuclease G9X25_RS17050 ENOG4105F27 Major Facilitator G9X25_RS17055 ENOG4105DKQ ROK family G9X25_RS17070 ENOG4105HBA AroM protein G9X25_RS17075 ENOG4105SS3 G9X25_RS17090 ENOG4105II7 pyrroline-5-carboxylate reductase G9X25_RS17095 ENOG4105BZU Histidine kinase G9X25_RS17100 ENOG4105VIF phosphate starvation-inducible protein G9X25_RS17120 ENOG4105CPF Cell wall formation (By similarity) G9X25_RS17125 ENOG4105UNH Membrane G9X25_RS17130 ENOG4105FR5 inner membrane protein YaiY G9X25_RS17135 ENOG4107QS8 (LipO)protein G9X25_RS17140 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 G9X25_RS17145 ENOG4107R6D beta-lactam binding protein AmpH G9X25_RS17150 ENOG4108PNB DNA-binding transcriptional regulator G9X25_RS17155 ENOG4108NSE outer membrane autotransporter barrel G9X25_RS17160 ENOG4105D52 delta-aminolevulinic acid dehydratase G9X25_RS17165 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) G9X25_RS17170 ENOG4105DXD 2-methylcitrate dehydratase G9X25_RS17175 ENOG4105BZN citrate synthase G9X25_RS17180 ENOG4105CR4 methylisocitrate lyase G9X25_RS17185 ENOG4108JU7 Transcriptional regulator G9X25_RS17190 ENOG4105TDT uncharacterized protein yahO G9X25_RS17195 ENOG4105E82 cytochrome subunit of dehydrogenase G9X25_RS17215 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii G9X25_RS17220 ENOG4105C4M (Ubiquinol oxidase) subunit I G9X25_RS17230 ENOG4105D8D Type III G9X25_RS17235 ENOG4107QMH DNA methylase G9X25_RS17240 ENOG4105JHE Major Facilitator Superfamily G9X25_RS17260 ENOG41084HI prevent-host-death family G9X25_RS17290 ENOG4105FCK Membrane G9X25_RS17305 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) G9X25_RS17310 ENOG4105CIN aminoacyl-histidine dipeptidase G9X25_RS17315 ENOG4108S2Y peptide Chain Release factor G9X25_RS17330 ENOG4105F7V ErfK ybiS ycfS ynhG family protein G9X25_RS17335 ENOG4105E7A Glutamine amidotransferase G9X25_RS17345 ENOG4107QPN acyl-Coa dehydrogenase G9X25_RS17350 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase G9X25_RS17360 ENOG4105T40 surface antigen msp4 family protein G9X25_RS17370 ENOG4105W7K Transcriptional regulator G9X25_RS17435 ENOG4107TV1 YD repeat protein G9X25_RS17445 ENOG4105CNA YD repeat protein G9X25_RS17455 ENOG4105CS6 Rhs element vgr protein G9X25_RS17475 ENOG4105CNA YD repeat protein G9X25_RS17485 ENOG4105CS6 Rhs element vgr protein G9X25_RS17570 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit G9X25_RS17610 ENOG4107RZZ dna polymerase iii epsilon subunit G9X25_RS17615 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) G9X25_RS17620 ENOG4105D1A Methyltransferase G9X25_RS17630 ENOG4105E9H Lytic Murein transglycosylase G9X25_RS17635 ENOG4105F2W methyltransferase G9X25_RS17645 ENOG4105F27 Major Facilitator G9X25_RS17650 ENOG4105HEI LysR family (Transcriptional regulator G9X25_RS17655 ENOG4105CV8 reductase G9X25_RS17690 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase G9X25_RS17695 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) G9X25_RS17700 ENOG4108UMI ABC transporter, permease G9X25_RS17705 ENOG4105D01 (LipO)protein G9X25_RS17710 ENOG4108R8X outer membrane lipoprotein G9X25_RS17715 ENOG4108R96 Methyltransferase, YaeB family G9X25_RS17725 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion G9X25_RS17730 ENOG4108YZN class I peptide chain release factor G9X25_RS17735 ENOG4108VWS Yaeq family G9X25_RS17745 ENOG4105M1T rho-binding antiterminator G9X25_RS17750 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) G9X25_RS17755 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase G9X25_RS17760 ENOG4105CXN decarboxylase G9X25_RS17775 ENOG4105C0B DNA polymerase III (alpha subunit) G9X25_RS17795 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) G9X25_RS17800 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) G9X25_RS17805 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) G9X25_RS17820 ENOG4105KNE Phosphatidate cytidylyltransferase G9X25_RS17835 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) G9X25_RS17840 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) G9X25_RS17850 ENOG4105CE9 30S ribosomal protein S2 G9X25_RS17855 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) G9X25_RS17865 ENOG4105DMJ Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity) G9X25_RS17870 ENOG4105CSH Transporter G9X25_RS17885 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR G9X25_RS17890 ENOG4105C0H protease G9X25_RS17905 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) G9X25_RS17910 ENOG4105EN6 Membrane G9X25_RS17915 ENOG4108YX9 iron--sulfur cluster insertion protein erpA G9X25_RS17930 ENOG4105S6R Iron-hydroxamate transporter permease subunit G9X25_RS17935 ENOG4105J76 Periplasmic binding protein G9X25_RS17940 ENOG4105E0A ABC, transporter G9X25_RS17945 ENOG4105E0K tonB-dependent siderophore receptor G9X25_RS17950 ENOG4105BZ4 penicillin-binding protein G9X25_RS17955 ENOG4105CQ7 ATP-dependent helicase G9X25_RS17960 ENOG4107XID 2'-5' rna ligase G9X25_RS17970 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters G9X25_RS17980 ENOG4105DJ0 Poly(A) Polymerase G9X25_RS18000 ENOG4108VEV chaperone G9X25_RS18005 ENOG4105CW0 outer membrane usher protein G9X25_RS18015 ENOG4105SYG Fimbrial protein G9X25_RS18020 ENOG4105SN2 fimbrial-like adhesin protein G9X25_RS18030 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) G9X25_RS18050 ENOG4108VEV chaperone G9X25_RS18055 ENOG4105CW0 outer membrane usher protein G9X25_RS18060 ENOG4108XEY fimbrial-like adhesin protein G9X25_RS18080 ENOG4107BJW polysaccharide deacetylase G9X25_RS18085 ENOG4108YTN IIa component G9X25_RS18090 ENOG4105E3A (ABC) transporter G9X25_RS18095 ENOG4105DA5 (ABC) transporter G9X25_RS18100 ENOG41077A9 carbonic anhydrase G9X25_RS18105 ENOG4108UGV hypoxanthine phosphoribosyltransferase G9X25_RS18110 ENOG4105DZG Dehydrogenase G9X25_RS18115 ENOG4105E3B Multicopper oxidase G9X25_RS18120 ENOG4108ZRK uncharacterized protein yacC G9X25_RS18135 ENOG4105MVE transcriptional regulator G9X25_RS18140 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) G9X25_RS18145 ENOG4107S2N Type III effector Hrp-dependent G9X25_RS18150 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) G9X25_RS18160 ENOG4107QIJ Aconitate hydratase 2 G9X25_RS18165 ENOG4108NST exported protein G9X25_RS18180 ENOG4107QN2 dihydrolipoyl dehydrogenase G9X25_RS18185 ENOG4107QSN dihydrolipoamide acetyltransferase G9X25_RS18190 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) G9X25_RS18205 ENOG4105CT4 transporter G9X25_RS18210 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) G9X25_RS18215 ENOG4106A72 regulatory protein AmpE G9X25_RS18225 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase G9X25_RS18230 ENOG4108ZUW Major pilin subunit G9X25_RS18235 ENOG4107QHF type ii secretion system protein e G9X25_RS18240 ENOG4105D7Q type ii secretion system G9X25_RS18250 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) G9X25_RS18265 ENOG4105M6F mutator MutT protein G9X25_RS18270 ENOG4108RS6 transposase G9X25_RS18290 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) G9X25_RS18295 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) G9X25_RS18300 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) G9X25_RS18305 ENOG4105CPF Cell wall formation (By similarity) G9X25_RS18320 ENOG4105CNI cell division protein FtsW G9X25_RS18330 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) G9X25_RS18335 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) G9X25_RS18340 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) G9X25_RS18345 ENOG4105CJN penicillin-binding protein G9X25_RS18350 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) G9X25_RS18365 ENOG4107B7Y DNA-binding transcriptional regulator FruR G9X25_RS18370 ENOG4108ZP8 Acetolactate synthase small subunit G9X25_RS18375 ENOG4105C7K acetolactate synthase G9X25_RS18380 ENOG41064T2 transcriptional regulator, lysR family G9X25_RS18405 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) G9X25_RS18430 ENOG4107T0D ABC, transporter G9X25_RS18435 ENOG4108KF1 Membrane G9X25_RS18440 ENOG41063TF transcriptional regulator (AraC G9X25_RS18455 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase G9X25_RS18475 ENOG4105CQ2 DNA polymerase G9X25_RS18485 ENOG4105D3G Pseudouridine synthase G9X25_RS18495 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) G9X25_RS18505 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) G9X25_RS18515 ENOG4105NWN ApaG protein G9X25_RS18555 ENOG4105M5B (LipO)protein G9X25_RS18560 ENOG4105C54 Major Facilitator superfamily G9X25_RS18565 ENOG4105WQV ferredoxin-like protein G9X25_RS18570 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase G9X25_RS18595 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F G9X25_RS18615 ENOG4108XNW Transcriptional activatory protein CaiF G9X25_RS18620 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain G9X25_RS18625 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain G9X25_RS18650 ENOG4105CHY citrate lyase, alpha G9X25_RS18655 ENOG4105CI0 Citrate lyase G9X25_RS18665 ENOG4105DUA (citrate (pro-3S)-lyase ligase G9X25_RS18670 ENOG4105D2K citrate carrier protein G9X25_RS18690 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism G9X25_RS18695 ENOG4106YYS transcriptional regulatory protein G9X25_RS18715 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase G9X25_RS18730 ENOG4105DTN riboflavin biosynthesis protein ribF G9X25_RS18735 ENOG410647N response to DNA damage stimulus G9X25_RS18755 ENOG41063Z6 transcriptional regulator, lysR family G9X25_RS18775 ENOG4105C4X radical SAM domain protein G9X25_RS18780 ENOG41061MV Arylsulfatase G9X25_RS18790 ENOG4105CGH 5'-nucleotidase G9X25_RS18805 ENOG4105DQS Transcriptional regulator G9X25_RS18825 ENOG4106PH7 chaperone G9X25_RS18840 ENOG4105MHR Fimbrial protein G9X25_RS18845 ENOG4105CW0 outer membrane usher protein G9X25_RS18850 ENOG4108AF8 Chaperone G9X25_RS18910 ENOG4108QUJ UPF0174 protein YaaW G9X25_RS18915 ENOG4106HK8 GPR1 FUN34 yaaH family protein G9X25_RS18920 ENOG4108RIR Molybdenum cofactor biosynthesis protein G9X25_RS18925 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) G9X25_RS18930 ENOG4105BZG amino acid carrier protein G9X25_RS18940 ENOG4105D98 threonine synthase G9X25_RS18950 ENOG4105CFH Aspartokinase G9X25_RS18960 ENOG4106FVC RNA methyltransferase G9X25_RS18965 ENOG410759A G9X25_RS18970 ENOG41065U4 response regulator G9X25_RS18980 ENOG4108PNB DNA-binding transcriptional regulator G9X25_RS18990 ENOG4108VCD Chaperone G9X25_RS18995 ENOG4105CW0 outer membrane usher protein G9X25_RS19010 ENOG4105CT7 inner membrane cred family protein G9X25_RS19015 ENOG4105EB3 Histidine kinase G9X25_RS19020 ENOG4105E3W Two component transcriptional regulator (Winged helix family G9X25_RS19025 ENOG4108RH0 Crea protein G9X25_RS19030 ENOG4105UEI Transcriptional Regulator AraC Family G9X25_RS19040 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) G9X25_RS19050 ENOG4107SC1 transglycosylase G9X25_RS19055 ENOG4105C5H ABC transporter G9X25_RS19060 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase G9X25_RS19065 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) G9X25_RS19070 ENOG4105EAC phosphoserine phosphatase G9X25_RS19075 ENOG41062Z9 Membrane G9X25_RS19085 ENOG4105EUP HipA domain protein G9X25_RS19110 ENOG4105G0K glycine radical enzyme YjjI family G9X25_RS19115 ENOG41076CZ activating enzyme G9X25_RS19120 ENOG4105EYA deoxyribonuclease G9X25_RS19125 ENOG4108NRW Phospholipase, patatin family G9X25_RS19135 ENOG4105K3G Periplasmic Protein G9X25_RS19145 ENOG4105PAD Hydrolase G9X25_RS19150 ENOG4105KEG ribosomal-protein-alanine acetyltransferase G9X25_RS19155 ENOG4108WPU DNA polymerase III subunit psi G9X25_RS19175 ENOG4105YBH Protein of unknown function (DUF1435) G9X25_RS19180 ENOG4105BZU Histidine kinase G9X25_RS19185 ENOG4108819 ferric iron reductase G9X25_RS19190 ENOG4108UIN ybak prolyl-trna synthetase associated region G9X25_RS19195 ENOG4108T94 DNA-binding transcriptional activator BglJ G9X25_RS19200 ENOG4108N8T regulatoR G9X25_RS19205 ENOG4105DWK Membrane G9X25_RS19220 ENOG4106CVF DNA replication protein G9X25_RS19225 ENOG4105RI1 glycoprotein receptor G9X25_RS19235 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) G9X25_RS19240 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) G9X25_RS19245 ENOG4105F3R pts system mannose fructose sorbose family iid G9X25_RS19250 ENOG4105ETZ PTS System G9X25_RS19255 ENOG4108IQ3 PTS system G9X25_RS19270 ENOG4105C8Q Methyl-accepting chemotaxis G9X25_RS19275 ENOG4105D22 carbon starvation protein G9X25_RS19280 ENOG4105VCD cytoplasmic protein G9X25_RS19285 ENOG4105CKI cobalamin synthesis protein G9X25_RS19290 ENOG41063TF transcriptional regulator (AraC G9X25_RS19295 ENOG4105E82 cytochrome subunit of dehydrogenase G9X25_RS19300 ENOG4108HFV G9X25_RS19315 ENOG4105C26 Dehydrogenase G9X25_RS19320 ENOG4105DNE Transposase G9X25_RS19325 ENOG41083G8 Multidrug resistance protein MdtM G9X25_RS19330 ENOG4106BRA Membrane G9X25_RS19335 ENOG4105CBP Major Facilitator G9X25_RS19340 ENOG41074DU domain protein G9X25_RS19345 ENOG4108P2H Inner membrane protein YjiG G9X25_RS19350 ENOG4105DYB Isoaspartyl dipeptidase G9X25_RS19355 ENOG4107YNJ LysR family Transcriptional regulator G9X25_RS19375 ENOG4105C6F GntR Family Transcriptional Regulator G9X25_RS19395 ENOG4105KZM cytoplasmic protein G9X25_RS19405 ENOG4105DTA methyltransferase G9X25_RS19410 ENOG4105CDY transcriptional regulatory protein G9X25_RS19475 ENOG4105DQ4 alcohol dehydrogenase G9X25_RS19480 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family G9X25_RS19485 ENOG4105CPQ Dehydrogenase G9X25_RS19490 ENOG4105CHR reductase G9X25_RS19495 ENOG4105C6Z Gluconate G9X25_RS19500 ENOG4105K2J Transcriptional regulator G9X25_RS19505 ENOG4108K5H permease YjgP YjgQ family protein G9X25_RS19510 ENOG4108M8S permease YjgP YjgQ family protein G9X25_RS19520 ENOG4105MYG DNA polymerase iii, chi subunit G9X25_RS19525 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) G9X25_RS19530 ENOG4108M3P Membrane G9X25_RS19535 ENOG4108MJ3 acetyltransferase G9X25_RS19545 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase G9X25_RS19550 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) G9X25_RS19555 ENOG4105DBV ornithine carbamoyltransferase G9X25_RS19560 ENOG4105XEP YhcH YjgK YiaL family protein G9X25_RS19570 ENOG4105C5B carbamate kinase G9X25_RS19575 ENOG4105DBV ornithine carbamoyltransferase G9X25_RS19580 ENOG4105CSX c4-dicarboxylate anaerobic carrier G9X25_RS19585 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) G9X25_RS19595 ENOG41077AM PyrBI operon attenuator G9X25_RS19610 ENOG4105KME endoribonuclease L-psp G9X25_RS19630 ENOG4105D4X repressor G9X25_RS19635 ENOG4105C5Y PTS System G9X25_RS19640 ENOG4105CG3 alpha amylase, catalytic region G9X25_RS19645 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase G9X25_RS19650 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) G9X25_RS19655 ENOG4105K4U addiction module toxin, RelE StbE family G9X25_RS19665 ENOG4105EMD TRANSCRIPTIONal G9X25_RS19680 ENOG41069H0 dihydroorotase EC 3.5.2.3 G9X25_RS19710 ENOG4108XVM Cytochrome b(562) G9X25_RS19715 ENOG4105CMS peptidase U62, modulator of DNA gyrase G9X25_RS19725 ENOG4105DFU Cell wall formation (By similarity) G9X25_RS19735 ENOG4105F0N pyrophosphate phospho-hydrolase G9X25_RS19740 ENOG41069H0 dihydroorotase EC 3.5.2.3 G9X25_RS19745 ENOG4105DJB Major Facilitator Superfamily G9X25_RS19750 ENOG4108ZHD aig2 family G9X25_RS19770 ENOG4105C37 (CBS) domain G9X25_RS19775 ENOG41061GZ Protein of unknown function (DUF1107) G9X25_RS19780 ENOG4108UUE Transcriptional regulator G9X25_RS19785 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase G9X25_RS19790 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic G9X25_RS19795 ENOG4105KVH Transcriptional regulator G9X25_RS19800 ENOG4105ECR NmrA family G9X25_RS19805 ENOG4105DXC membrane G9X25_RS19820 ENOG4108V1T peptidylprolyl cis-trans isomerase G9X25_RS19825 ENOG4105FHY Opacity-associated protein A G9X25_RS19835 ENOG4105K9Q Binds to the 23S rRNA (By similarity) G9X25_RS19840 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) G9X25_RS19845 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) G9X25_RS19850 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) G9X25_RS19855 ENOG4105KIT UPF0379 protein yjfY G9X25_RS19860 ENOG4105R3P Inner membrane protein yagU G9X25_RS19890 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC G9X25_RS19905 ENOG4108MXZ Esterase G9X25_RS19910 ENOG4105WSB biofilm stress and motility protein A G9X25_RS19915 ENOG4105S17 UPF0379 protein yjfN G9X25_RS19920 ENOG4105CSU acyl-Coa dehydrogenase G9X25_RS19925 ENOG4106032 Glutathionylspermidine synthase G9X25_RS19930 ENOG4108KXT Conserved Protein G9X25_RS19935 ENOG4105Z6B inner membrane protein yjfl G9X25_RS19940 ENOG4107VNS Protein of unknown function (DUF2491) G9X25_RS19945 ENOG4108P9J Phage shock protein A G9X25_RS19950 ENOG4105FUX Conserved Protein G9X25_RS19955 ENOG4105C2N RNA methyltransferase TrmH family group 3 G9X25_RS19960 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) G9X25_RS19980 ENOG4105EPW hflc protein G9X25_RS19985 ENOG4107QJR hflk protein G9X25_RS19990 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) G9X25_RS19995 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) G9X25_RS20010 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase G9X25_RS20015 ENOG4105K8N protein family UPF0079, ATPase G9X25_RS20020 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) G9X25_RS20025 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) G9X25_RS20045 ENOG4106TNF Periplasmic binding protein G9X25_RS20050 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) G9X25_RS20065 ENOG4105EGS Mechanosensitive ion channel G9X25_RS20070 ENOG4107SC7 Inner membrane transporter yjeM G9X25_RS20075 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) G9X25_RS20080 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) G9X25_RS20085 ENOG4105E33 succinate dehydrogenase G9X25_RS20095 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) G9X25_RS20105 ENOG4105KPY Small multidrug resistance protein G9X25_RS20115 ENOG4106BSU Entericidin B G9X25_RS20125 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) G9X25_RS20130 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein G9X25_RS20135 ENOG4105MTB Uncharacterized protein YjeJ G9X25_RS20140 ENOG4108ZVF (LipO)protein G9X25_RS20155 ENOG4105DVH amino acid G9X25_RS20160 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 G9X25_RS20165 ENOG4108IJ0 Aspartate ammonia-lyase G9X25_RS20170 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter G9X25_RS20185 ENOG4108SIC Transcriptional regulator G9X25_RS20200 ENOG4105SBG acid phosphatase G9X25_RS20220 ENOG41068CG regulatoR G9X25_RS20235 ENOG4108ZK4 sdia-regulated domain-containing protein G9X25_RS20245 ENOG4108NEM leader-binding protein dmsD G9X25_RS20250 ENOG4107KGK dmso reductase anchor subunit G9X25_RS20255 ENOG4105QAX Iron-sulfur G9X25_RS20260 ENOG4107QY8 reductase G9X25_RS20265 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism G9X25_RS20270 ENOG4108MRH transcriptional regulatory protein G9X25_RS20280 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter G9X25_RS20285 ENOG4107GFK fumarate G9X25_RS20290 ENOG4105CT4 transporter G9X25_RS20295 ENOG4105F8D glycoside hydrolase family 4 G9X25_RS20300 ENOG4108K2B transcriptional regulator G9X25_RS20305 ENOG4105CXN decarboxylase G9X25_RS20310 ENOG4106ZGR Transcriptional regulator G9X25_RS20315 ENOG4105D5Q Arginine ornithine antiporter G9X25_RS20320 ENOG4105DIJ Phosphoethanolamine transferase G9X25_RS20325 ENOG4105XJC Two component transcriptional regulator (Winged helix family G9X25_RS20330 ENOG4105ECM Sensor protein basS pmrB G9X25_RS20340 ENOG4105CSH Transporter G9X25_RS20345 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA G9X25_RS20350 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase G9X25_RS20355 ENOG410870W N-acetyltransferase G9X25_RS20370 ENOG41082ND Uncharacterized protein yjcO G9X25_RS20375 ENOG4105CK2 sodium dicarboxylate symporter G9X25_RS20380 ENOG4108W0S formate-dependent nitrite reductase complex G9X25_RS20385 ENOG4108QKW cytochrome c-type biogenesis protein G9X25_RS20390 ENOG4105DVI reductase, NrfD G9X25_RS20395 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G9X25_RS20400 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit G9X25_RS20410 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) G9X25_RS20415 ENOG41062QD Membrane G9X25_RS20425 ENOG41067MG lrgb family G9X25_RS20435 ENOG4105CMU LysR family (Transcriptional regulator G9X25_RS20440 ENOG4105EEQ Na H antiporter G9X25_RS20445 ENOG4105C7N Xanthine uracil vitamin C permease G9X25_RS20455 ENOG4108Z4X TRANSCRIPTIONal G9X25_RS20460 ENOG4108W3Q Transcriptional regulator G9X25_RS20465 ENOG4108M8H domain protein G9X25_RS20470 ENOG4105PMV Membrane G9X25_RS20505 ENOG4108UUM single-stranded DNA-binding protein G9X25_RS20510 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) G9X25_RS20525 ENOG4105MSB protein, conserved in bacteria G9X25_RS20530 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme G9X25_RS20535 ENOG4105F0S class B acid phosphatase G9X25_RS20540 ENOG4105CGF Aromatic amino acid aminotransferase G9X25_RS20545 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) G9X25_RS20550 ENOG4105CDU Replicative dna helicase G9X25_RS20555 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein G9X25_RS20560 ENOG4105P4Z Phage shock protein G G9X25_RS20565 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) G9X25_RS20575 ENOG4105MYN Zinc uptake regulation protein G9X25_RS20580 ENOG4105VDW Csbd family G9X25_RS20590 ENOG4107R73 Mate efflux family protein G9X25_RS20595 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) G9X25_RS20600 ENOG41080IJ Diacylglycerol kinase G9X25_RS20620 ENOG4107W52 maltose operon periplasmic protein G9X25_RS20630 ENOG4108IJ9 (ABC) transporter G9X25_RS20635 ENOG4107FKK extracellular solute-binding protein family 1 G9X25_RS20640 ENOG4105D56 permease protein G9X25_RS20645 ENOG4105EG2 ABC transporter, permease G9X25_RS20655 ENOG4105E3R (LipO)protein G9X25_RS20660 ENOG4108Q9C Periplasmic Protein G9X25_RS20665 ENOG4108MDC (LipO)protein G9X25_RS20675 ENOG4107QP8 phosphohexose isomerase G9X25_RS20680 ENOG4105CFH Aspartokinase G9X25_RS20805 ENOG4108KP7 hydrolase G9X25_RS20810 ENOG4105E98 transcriptional regulator DeoR family G9X25_RS20815 ENOG4108ZR5 Conserved Protein G9X25_RS20820 ENOG4105FE9 pseudouridine synthase G9X25_RS20825 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme G9X25_RS20840 ENOG4105EAM Na Pi-cotransporter G9X25_RS20845 ENOG4105C3R Methionine synthase G9X25_RS20850 ENOG41069M3 Transcriptional regulator G9X25_RS20865 ENOG4108I9X Isocitrate lyase G9X25_RS20870 ENOG4107QP3 malate synthase g G9X25_RS20880 ENOG4105K5X acetyltransferase G9X25_RS20910 ENOG4105C12 Phosphoribosylglycinamide synthetase G9X25_RS20915 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family G9X25_RS20920 ENOG4105BZU Histidine kinase G9X25_RS20930 ENOG4108T8B Protein of unknown function (DUF1481) G9X25_RS20935 ENOG4105K70 DNA-binding protein G9X25_RS20940 ENOG4105R2J Conserved Protein G9X25_RS20975 ENOG4105D06 uba thif-type nad fad binding protein G9X25_RS20980 ENOG4105WHD thiamine biosynthesis protein ThiS G9X25_RS20990 ENOG4105D41 biosynthesis protein thiH G9X25_RS21010 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) G9X25_RS21015 ENOG4107QIH DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) G9X25_RS21020 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) G9X25_RS21025 ENOG4108VZM 50s ribosomal protein L10 G9X25_RS21040 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) G9X25_RS21045 ENOG4105PM1 preprotein translocase subunit SecE G9X25_RS21050 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) G9X25_RS21085 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase G9X25_RS21095 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) G9X25_RS21100 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) G9X25_RS21105 ENOG4105CTX dehydratase G9X25_RS21115 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) G9X25_RS21120 ENOG4105DIV Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity) G9X25_RS21125 ENOG4107HP6 Transcriptional regulator G9X25_RS21175 ENOG4108Y73 Membrane G9X25_RS21190 ENOG4105C5Q Transcriptional regulator G9X25_RS21220 ENOG4105DIJ Phosphoethanolamine transferase G9X25_RS21225 ENOG4106R3P AraC family transcriptional regulator G9X25_RS21235 ENOG4105DCT glycerol dehydrogenase G9X25_RS21245 ENOG4105SYT Methylenetetrahydrofolate reductase G9X25_RS21250 ENOG4105CGH 5'-nucleotidase G9X25_RS21265 ENOG4105D64 Mechanosensitive ion channel G9X25_RS21270 ENOG4105CFH Aspartokinase G9X25_RS21275 ENOG4105C28 cystathionine G9X25_RS21285 ENOG4108MR7 Arylsulfotransferase G9X25_RS21305 ENOG4105C25 Primosomal protein n' G9X25_RS21310 ENOG4105ETE Transcriptional regulator (LacI family G9X25_RS21315 ENOG41063M6 Cell Division Protein G9X25_RS21330 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase G9X25_RS21345 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) G9X25_RS21355 ENOG4105CBT Fructose-1,6-bisphosphatase G9X25_RS21360 ENOG4105DP0 ferredoxin-NADP reductase G9X25_RS21365 ENOG4108VTS Membrane G9X25_RS21370 ENOG4105EBK exported protein G9X25_RS21395 ENOG4105D4B ABC, transporter G9X25_RS21410 ENOG4105C2J ABC transporter G9X25_RS21420 ENOG4107RYS Autoinducer-2 (AI-2) kinase G9X25_RS21450 ENOG4105D7K pfkb domain protein G9X25_RS21455 ENOG4105CT4 transporter G9X25_RS21465 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein G9X25_RS21470 ENOG4105CTQ phosphohexokinase G9X25_RS21480 ENOG4105FMW periplasmic G9X25_RS21485 ENOG4105E3W Two component transcriptional regulator (Winged helix family G9X25_RS21490 ENOG4105E0F Histidine kinase G9X25_RS21500 ENOG4108RPX mosc domain containing protein G9X25_RS21505 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) G9X25_RS21510 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit G9X25_RS21515 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter G9X25_RS21520 ENOG4105CG6 trap dicarboxylate transporter dctm subunit G9X25_RS21525 ENOG4108QGT oligogalacturonate-specific porin G9X25_RS21550 ENOG4105DKG l-rhamnose isomerase G9X25_RS21560 ENOG4105C0A alcohol dehydrogenase G9X25_RS21575 ENOG4108UMN azlc family G9X25_RS21585 ENOG4108V87 frv operon regulatory protein G9X25_RS21600 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G9X25_RS21605 ENOG4108MG3 formate dehydrogenase G9X25_RS21630 ENOG4105SUU thioesterase domain G9X25_RS21645 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 G9X25_RS21650 ENOG4105E98 transcriptional regulator DeoR family G9X25_RS21655 ENOG4108MGF sugar kinase G9X25_RS21660 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase G9X25_RS21665 ENOG4105D2M Aldolase G9X25_RS21670 ENOG4107QKS N-acylglucosamine 2-epimerase G9X25_RS21675 ENOG4107WI4 Aldose-1-epimerase G9X25_RS21680 ENOG4105CJQ hydrolase, family 31 G9X25_RS21685 ENOG4105CT4 transporter G9X25_RS21690 ENOG4105CT4 transporter G9X25_RS21695 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is G9X25_RS21725 ENOG4108K4B hydrolase G9X25_RS21730 ENOG4105CI3 gtp-binding protein typa G9X25_RS21735 ENOG4105C5F glutamine synthetase G9X25_RS21740 ENOG4105CUX Signal transduction histidine kinase G9X25_RS21745 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family G9X25_RS21750 ENOG4106FIY G9X25_RS21755 ENOG4105D4P Coproporphyrinogen iii oxidase G9X25_RS21775 ENOG4105C2M dna polymerase I G9X25_RS21780 ENOG4106HNH Acyl-transferase G9X25_RS21785 ENOG4108Z33 Thiol disulfide Interchange Protein G9X25_RS21795 ENOG4105PC1 Conserved Protein G9X25_RS21800 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) G9X25_RS21805 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b G9X25_RS21835 ENOG4108RR8 protoporphyrinogen oxidase G9X25_RS21840 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) G9X25_RS21845 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein G9X25_RS21860 ENOG4105CHU acetyl-coa acetyltransferase G9X25_RS21865 ENOG4108MR7 Arylsulfotransferase G9X25_RS21870 ENOG4107QK7 reductase G9X25_RS21875 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) G9X25_RS21880 ENOG4105MDZ Transcriptional activator rfaH G9X25_RS21885 ENOG4105F8V Hydrolase, tatD family G9X25_RS21890 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) G9X25_RS21895 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) G9X25_RS21900 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) G9X25_RS21910 ENOG4105JC1 sterol-binding domain protein G9X25_RS21920 ENOG4105CGY Dna recombination protein G9X25_RS21925 ENOG4107SXA Phosphorylase G9X25_RS21930 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) G9X25_RS21935 ENOG4105C4X radical SAM domain protein G9X25_RS21940 ENOG4105JP4 Inner membrane protein yidG G9X25_RS21945 ENOG4105VG5 Membrane G9X25_RS21970 ENOG4105DZ2 Transcriptional regulator G9X25_RS21975 ENOG4105EMK carboxylate amino acid amine transporter G9X25_RS21980 ENOG4105DQF Hydrolase G9X25_RS21985 ENOG4108EUD Lysophospholipase G9X25_RS21990 ENOG410829K Lysine exporter protein (Lyse ygga) G9X25_RS21995 ENOG4105CCF Lysine exporter protein (Lyse ygga) G9X25_RS22000 ENOG4105C9U ATP-dependent DNA helicase RecQ G9X25_RS22005 ENOG4105HDD phospholipase G9X25_RS22010 ENOG4108VUY thioesterase Superfamily protein G9X25_RS22015 ENOG4105FR1 rard protein G9X25_RS22030 ENOG4107QUT magnesium and cobalt transport protein CorA G9X25_RS22035 ENOG4105C4R Atp-dependent dna helicase G9X25_RS22040 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant G9X25_RS22045 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) G9X25_RS22050 ENOG4105CT0 Protein of unknown function, DUF484 G9X25_RS22060 ENOG4105S7Z (LipO)protein G9X25_RS22070 ENOG4107T0K Adenylate cyclase G9X25_RS22080 ENOG41076E6 Uroporphyrinogen-III Synthase G9X25_RS22085 ENOG4105ECF c-methyltransferase G9X25_RS22090 ENOG410601J HemY protein G9X25_RS22115 ENOG4105C85 amino acid G9X25_RS22135 ENOG4105EGZ biosynthesis protein G9X25_RS22140 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase G9X25_RS22145 ENOG4108WJ1 acetyltransferase G9X25_RS22150 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) G9X25_RS22155 ENOG4105C1B dTDP-glucose 4-6-dehydratase G9X25_RS22160 ENOG4108IJ1 Dehydrogenase G9X25_RS22165 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase G9X25_RS22170 ENOG4105SFE lipopolysaccharide biosynthesis protein G9X25_RS22175 ENOG4105ESV Glycosyl transferase, family 4 G9X25_RS22180 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) G9X25_RS22205 ENOG4105C4R Atp-dependent dna helicase G9X25_RS22210 ENOG4105KQ5 peptidylprolyl cis-trans isomerase G9X25_RS22220 ENOG4105EMY transcriptional regulator G9X25_RS22235 ENOG4105C7B Threonine dehydratase G9X25_RS22245 ENOG4105CM2 brancheD-chain amino acid aminotransferase G9X25_RS22250 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit G9X25_RS22265 ENOG4105C0P Mg chelatase subunit ChlI G9X25_RS22310 ENOG4107EJG GntR family transcriptional regulator G9X25_RS22315 ENOG4105C0R drug resistance transporter emrb qaca subfamily G9X25_RS22320 ENOG4105ETE Transcriptional regulator (LacI family G9X25_RS22325 ENOG4108RVA ribokinase G9X25_RS22330 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator G9X25_RS22335 ENOG4105CNN ABC, transporter G9X25_RS22340 ENOG4105C2J ABC transporter G9X25_RS22370 ENOG4108VVK transcriptional Regulator, AsnC G9X25_RS22375 ENOG4105QTB Flavodoxin G9X25_RS22390 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation G9X25_RS22405 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) G9X25_RS22425 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) G9X25_RS22430 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) G9X25_RS22450 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) G9X25_RS22455 ENOG4105F9E Shikimate 5-dehydrogenase G9X25_RS22460 ENOG4105DM4 PTS System G9X25_RS22465 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) G9X25_RS22470 ENOG4105C8U phosphate abc transporter G9X25_RS22475 ENOG4105E2Z phosphate ABC transporter (Permease G9X25_RS22480 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) G9X25_RS22490 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 G9X25_RS22495 ENOG4105C7N Xanthine uracil vitamin C permease G9X25_RS22500 ENOG4108YYH Nadph-dependent fmn reductase G9X25_RS22505 ENOG4105E8Q phosphopantetheinyl transferase G9X25_RS22540 ENOG4105VG0 50S ribosomal protein l34