locus-tag	class	description
GER12_RS00005	COG2766	serine protein kinase
GER12_RS00020	COG2199	diguanylate cyclase activity
GER12_RS00025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GER12_RS00040	COG2207	Transcriptional regulator
GER12_RS00045	COG2807	transmembrane transport
GER12_RS00050	COG3189	MarR family transcriptional regulator
GER12_RS00060	COG3042	response to heat
GER12_RS00070	COG2261	transglycosylase associated protein
GER12_RS00085	COG3615	Tellurite resistance protein tehB
GER12_RS00095	COG1605	Chorismate mutase
GER12_RS00110	COG0789	Transcriptional regulator
GER12_RS00125	COG3443	Belongs to the bacterial solute-binding protein 9 family
GER12_RS00140	COG0668	transmembrane transport
GER12_RS00145	COG1124	(ABC) transporter
GER12_RS00165	COG0747	negative chemotaxis
GER12_RS00175	COG3038	cytochrome b561
GER12_RS00185	COG0071	Belongs to the small heat shock protein (HSP20) family
GER12_RS00245	COG0538	isocitrate dehydrogenase activity
GER12_RS00275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GER12_RS00290	COG2850	peptidyl-arginine hydroxylation
GER12_RS00320	COG1177	transmembrane transport
GER12_RS00340	COG4591	ABC-type transport system involved in lipoprotein release permease component
GER12_RS00345	COG1136	(ABC) transporter
GER12_RS00350	COG4591	ABC-type transport system involved in lipoprotein release permease component
GER12_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GER12_RS00360	COG1388	LysM domain
GER12_RS00360	COG1376	ErfK ybiS ycfS ynhG family protein
GER12_RS00370	COG1309	transcriptional regulator
GER12_RS00375	COG3134	Outer membrane lipoprotein
GER12_RS00380	COG1252	NADH dehydrogenase
GER12_RS00405	COG5633	Lipoprotein
GER12_RS00410	COG0537	adenosine 5'-monophosphoramidase activity
GER12_RS00415	COG4773	Receptor
GER12_RS00425	COG0084	hydrolase, TatD family'
GER12_RS00430	COG0470	DNA polymerase III
GER12_RS00440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GER12_RS00445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GER12_RS00450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GER12_RS00510	COG1530	ribonuclease E activity
GER12_RS00600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GER12_RS00610	COG2999	glutathione oxidoreductase activity
GER12_RS00645	COG3038	cytochrome b561
GER12_RS00660	COG1560	Kdo2-lipid A biosynthetic process
GER12_RS00675	COG5645	(Lipo)protein
GER12_RS00695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GER12_RS00750	COG3381	protein complex oligomerization
GER12_RS00770	COG0673	inositol 2-dehydrogenase activity
GER12_RS00775	COG2814	Major facilitator Superfamily
GER12_RS00795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GER12_RS00800	COG1737	Transcriptional regulator
GER12_RS00805	COG1702	phosphate starvation-inducible protein PhoH
GER12_RS00825	COG1309	transcriptional regulator
GER12_RS00830	COG3729	General stress protein
GER12_RS00850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GER12_RS00855	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GER12_RS00855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GER12_RS00860	COG4232	protein-disulfide reductase activity
GER12_RS00905	COG3971	2-oxopent-4-enoate hydratase activity
GER12_RS00915	COG3384	dioxygenase
GER12_RS00920	COG1012	belongs to the aldehyde dehydrogenase family
GER12_RS00930	COG1846	Transcriptional regulator
GER12_RS00935	COG2368	4-hydroxyphenylacetate
GER12_RS00950	COG0745	RESPONSE REGULATOR receiver
GER12_RS00955	COG2205	protein histidine kinase activity
GER12_RS01005	COG0670	Belongs to the BI1 family
GER12_RS01025	COG1881	PFAM PEBP family protein
GER12_RS01040	COG1832	CoA-binding protein
GER12_RS01055	COG0210	DNA helicase
GER12_RS01060	COG3304	Inner membrane component domain
GER12_RS01065	COG1289	transmembrane transporter activity
GER12_RS01070	COG3070	regulator of competence-specific genes
GER12_RS01090	COG1067	ATP-dependent peptidase activity
GER12_RS01100	COG3130	regulation of translation
GER12_RS01105	COG3009	Protein conserved in bacteria
GER12_RS01110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GER12_RS01110	COG3008	intermembrane lipid transfer
GER12_RS01115	COG2995	paraquat-inducible protein a
GER12_RS01120	COG0488	(ABC) transporter
GER12_RS01130	COG3217	Mosc domain protein beta barrel domain protein
GER12_RS01130	COG0633	Ferredoxin
GER12_RS01145	COG0308	aminopeptidase N
GER12_RS01155	COG1115	amino acid carrier protein
GER12_RS01165	COG1522	sequence-specific DNA binding
GER12_RS01170	COG0017	Asparaginyl-tRNA synthetase
GER12_RS01180	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GER12_RS01190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GER12_RS01195	COG3108	Peptidase M15
GER12_RS01200	COG2989	Protein conserved in bacteria
GER12_RS01210	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GER12_RS01220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GER12_RS01225	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GER12_RS01230	COG3173	Aminoglycoside phosphotransferase
GER12_RS01245	COG3214	Protein conserved in bacteria
GER12_RS01260	COG2333	competence protein COMEC
GER12_RS01260	COG0658	competence protein
GER12_RS01270	COG0539	negative regulation of cytoplasmic translation
GER12_RS01280	COG0501	Belongs to the peptidase M48B family
GER12_RS01295	COG2323	membrane
GER12_RS01300	COG1944	ATP diphosphatase activity
GER12_RS01305	COG2116	formate transmembrane transporter activity
GER12_RS01310	COG1882	Formate acetyltransferase
GER12_RS01325	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GER12_RS01330	COG0531	amino acid
GER12_RS01340	COG3302	dmso reductase anchor subunit
GER12_RS01345	COG0437	4 iron, 4 sulfur cluster binding
GER12_RS01350	COG0243	molybdopterin cofactor binding
GER12_RS01360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GER12_RS01380	COG0492	ferredoxin-NADP+ reductase activity
GER12_RS01385	COG4988	ABC transporter
GER12_RS01390	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GER12_RS01410	COG0583	DNA-binding transcription factor activity
GER12_RS01420	COG1335	isochorismatase
GER12_RS01535	COG0582	viral genome integration into host DNA
GER12_RS01550	COG0542	response to heat
GER12_RS01560	COG1278	Cold shock
GER12_RS01565	COG0577	efflux transmembrane transporter activity
GER12_RS01565	COG1136	(ABC) transporter
GER12_RS01570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GER12_RS01575	COG2990	Protein conserved in bacteria
GER12_RS01580	COG3593	DNA synthesis involved in DNA repair
GER12_RS01585	COG2431	L-lysine efflux transmembrane transporter activity
GER12_RS01595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GER12_RS01600	COG0028	Belongs to the TPP enzyme family
GER12_RS01605	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GER12_RS01610	COG0702	epimerase
GER12_RS01615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GER12_RS01620	COG3023	N-Acetylmuramoyl-L-alanine amidase
GER12_RS01635	COG1126	abc transporter atp-binding protein
GER12_RS01640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GER12_RS01645	COG4215	(ABC) transporter
GER12_RS01650	COG4160	amino acid transport
GER12_RS01655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GER12_RS01685	COG1177	transmembrane transport
GER12_RS01690	COG1176	ABC-type spermidine putrescine transport system, permease component I
GER12_RS01695	COG3842	ATPase activity
GER12_RS01700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GER12_RS01740	COG3226	Transcriptional regulator
GER12_RS01745	COG0738	Major facilitator superfamily
GER12_RS01750	COG0561	phosphatase activity
GER12_RS01755	COG2814	Major facilitator Superfamily
GER12_RS01760	COG0671	phosphoesterase, PA-phosphatase related
GER12_RS01765	COG1349	DNA-binding transcription factor activity
GER12_RS01770	COG1686	Belongs to the peptidase S11 family
GER12_RS01775	COG0625	glutathione transferase activity
GER12_RS01780	COG2133	pyrroloquinoline quinone binding
GER12_RS01785	COG2610	gluconate transmembrane transporter activity
GER12_RS01790	COG0583	DNA-binding transcription factor activity
GER12_RS01800	COG1960	acyl-CoA dehydrogenase activity
GER12_RS01820	COG2301	Belongs to the HpcH HpaI aldolase family
GER12_RS01845	COG0747	negative chemotaxis
GER12_RS01870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GER12_RS01875	COG1882	Formate acetyltransferase
GER12_RS01880	COG0561	phosphatase activity
GER12_RS01900	COG0488	(ABC) transporter
GER12_RS01905	COG1376	ErfK ybiS ycfS ynhG family protein
GER12_RS01910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GER12_RS01925	COG2194	sulfuric ester hydrolase activity
GER12_RS01930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GER12_RS01945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GER12_RS01950	COG0765	amino acid transport
GER12_RS01955	COG1126	abc transporter atp-binding protein
GER12_RS01960	COG0668	transmembrane transport
GER12_RS01970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GER12_RS01980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GER12_RS01990	COG0513	Belongs to the DEAD box helicase family
GER12_RS01995	COG1309	transcriptional regulator
GER12_RS02005	COG1131	(ABC) transporter
GER12_RS02010	COG0842	Transport permease protein
GER12_RS02015	COG0842	Transport permease protein
GER12_RS02025	COG3568	Endonuclease Exonuclease Phosphatase
GER12_RS02030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GER12_RS02035	COG0392	lysyltransferase activity
GER12_RS02055	COG0670	Belongs to the BI1 family
GER12_RS02065	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GER12_RS02075	COG0521	Mo-molybdopterin cofactor biosynthetic process
GER12_RS02100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GER12_RS02125	COG1881	PFAM PEBP family protein
GER12_RS02155	COG4677	pectinesterase activity
GER12_RS02165	COG0561	phosphatase activity
GER12_RS02175	COG4149	molybdate abc transporter
GER12_RS02180	COG0725	ABC transporter, periplasmic molybdate-binding protein
GER12_RS02190	COG2005	Transcriptional regulator
GER12_RS02190	COG3585	molybdate ion transport
GER12_RS02195	COG1119	ATPase activity
GER12_RS02220	COG2017	converts alpha-aldose to the beta-anomer
GER12_RS02230	COG1120	ATPase activity
GER12_RS02235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GER12_RS02245	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GER12_RS02260	COG0490	domain, Protein
GER12_RS02260	COG0471	metal ion transport
GER12_RS02265	COG0583	DNA-binding transcription factor activity
GER12_RS02270	COG0583	DNA-binding transcription factor activity
GER12_RS02280	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GER12_RS02280	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GER12_RS02285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GER12_RS02295	COG1230	cation diffusion facilitator family transporter
GER12_RS02335	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GER12_RS02340	COG2885	chlorophyll binding
GER12_RS02350	COG3064	Membrane
GER12_RS02355	COG0848	biopolymer transport protein
GER12_RS02360	COG0811	peptide transport
GER12_RS02365	COG0824	Thioesterase
GER12_RS02370	COG3790	cyd operon protein YbgE
GER12_RS02375	COG4890	Cyd operon protein YbgT
GER12_RS02380	COG1294	oxidase, subunit
GER12_RS02385	COG1271	oxidase subunit
GER12_RS02390	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GER12_RS02400	COG0508	dehydrogenase complex catalyzes the overall conversion of
GER12_RS02405	COG0567	Dehydrogenase, E1 component
GER12_RS02420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GER12_RS02440	COG3180	Ammonia monooxygenase
GER12_RS02465	COG1216	Glycosyl transferase, family 2
GER12_RS02505	COG0582	viral genome integration into host DNA
GER12_RS02520	COG1984	allophanate hydrolase subunit 2
GER12_RS02525	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GER12_RS02570	COG2205	protein histidine kinase activity
GER12_RS02575	COG0745	RESPONSE REGULATOR receiver
GER12_RS02585	COG1982	Orn Lys Arg decarboxylase major
GER12_RS02590	COG0531	amino acid
GER12_RS02600	COG0033	Phosphoglucomutase
GER12_RS02610	COG0596	Alpha beta hydrolase
GER12_RS02625	COG0735	belongs to the Fur family
GER12_RS02630	COG0583	DNA-binding transcription factor activity
GER12_RS02635	COG1053	succinate dehydrogenase
GER12_RS02675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GER12_RS02680	COG1940	carbohydrate kinase activity
GER12_RS02680	COG1846	Transcriptional regulator
GER12_RS02685	COG0647	UMP catabolic process
GER12_RS02690	COG0367	asparagine synthase
GER12_RS02730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GER12_RS02740	COG1702	phosphate starvation-inducible protein PhoH
GER12_RS02765	COG0765	amino acid transport
GER12_RS02770	COG0765	amino acid transport
GER12_RS02775	COG1126	abc transporter atp-binding protein
GER12_RS02790	COG0443	Heat shock 70 kDa protein
GER12_RS02795	COG2214	Heat shock protein DnaJ domain protein
GER12_RS02805	COG2214	Heat shock protein DnaJ domain protein
GER12_RS02820	COG2888	peptidyl-tyrosine sulfation
GER12_RS02825	COG3829	transcription factor binding
GER12_RS02825	COG3290	protein histidine kinase activity
GER12_RS02855	COG1466	dna polymerase III delta subunit
GER12_RS02875	COG0799	negative regulation of ribosome biogenesis
GER12_RS02885	COG0768	penicillin binding
GER12_RS02890	COG0772	Belongs to the SEDS family
GER12_RS02900	COG1686	Belongs to the peptidase S11 family
GER12_RS02915	COG0583	DNA-binding transcription factor activity
GER12_RS02930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GER12_RS02950	COG3069	C4-dicarboxylate transmembrane transporter activity
GER12_RS02955	COG4565	transcriptional regulatory protein
GER12_RS02960	COG3290	protein histidine kinase activity
GER12_RS02965	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GER12_RS02975	COG2301	Belongs to the HpcH HpaI aldolase family
GER12_RS02980	COG3051	citrate lyase alpha subunit
GER12_RS02995	COG0471	metal ion transport
GER12_RS03000	COG3719	Belongs to the RNase T2 family
GER12_RS03005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GER12_RS03010	COG1063	alcohol dehydrogenase
GER12_RS03030	COG0243	molybdopterin cofactor binding
GER12_RS03050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GER12_RS03055	COG0583	DNA-binding transcription factor activity
GER12_RS03060	COG3969	phosphoadenosine phosphosulfate
GER12_RS03065	COG1475	DNA binding
GER12_RS03070	COG0436	Aminotransferase
GER12_RS03075	COG0371	Dehydrogenase
GER12_RS03080	COG2879	small protein
GER12_RS03085	COG1966	Carbon starvation protein
GER12_RS03095	COG1028	Short-chain dehydrogenase reductase Sdr
GER12_RS03100	COG1535	isochorismatase
GER12_RS03100	COG3433	isochorismatase activity
GER12_RS03105	COG1021	2,3-dihydroxybenzoate-AMP ligase
GER12_RS03110	COG1169	isochorismate synthase
GER12_RS03115	COG4592	Periplasmic binding protein
GER12_RS03125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GER12_RS03130	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GER12_RS03135	COG1120	ATPase activity
GER12_RS03140	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GER12_RS03145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GER12_RS03145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GER12_RS03150	COG3251	PFAM MbtH domain protein
GER12_RS03155	COG2382	esterase
GER12_RS03160	COG4771	TonB-dependent receptor
GER12_RS03165	COG2977	Belongs to the P-Pant transferase superfamily
GER12_RS03190	COG2315	Protein conserved in bacteria
GER12_RS03215	COG3716	PTS system mannose fructose sorbose family IID component
GER12_RS03225	COG2222	sugar isomerase
GER12_RS03230	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GER12_RS03230	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GER12_RS03240	COG0668	transmembrane transport
GER12_RS03245	COG1113	amino acid transport
GER12_RS03255	COG3059	membrane
GER12_RS03265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GER12_RS03270	COG2207	Transcriptional regulator
GER12_RS03335	COG2501	S4 domain
GER12_RS03340	COG1988	membrane-bound metal-dependent
GER12_RS03360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GER12_RS03370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GER12_RS03375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GER12_RS03380	COG0549	Belongs to the carbamate kinase family
GER12_RS03390	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GER12_RS03395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GER12_RS03400	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GER12_RS03405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GER12_RS03410	COG3257	ureidoglycine aminohydrolase activity
GER12_RS03415	COG1929	Belongs to the glycerate kinase type-1 family
GER12_RS03420	COG2233	PERMEase
GER12_RS03430	COG1953	Uracil, thiamine, allantoin
GER12_RS03440	COG2084	Dehydrogenase
GER12_RS03445	COG3622	Belongs to the hyi family
GER12_RS03450	COG3960	tartronate-semialdehyde synthase activity
GER12_RS03485	COG1464	Belongs to the NlpA lipoprotein family
GER12_RS03495	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GER12_RS03500	COG4181	ATPase activity
GER12_RS03505	COG2755	lipolytic protein G-D-S-L family
GER12_RS03510	COG0300	oxidoreductase activity
GER12_RS03515	COG3118	belongs to the thioredoxin family
GER12_RS03520	COG0390	transport system, permease component
GER12_RS03525	COG4619	ABC transporter
GER12_RS03530	COG0330	HflC and HflK could
GER12_RS03535	COG1585	Membrane protein implicated in regulation of membrane protease activity
GER12_RS03545	COG2217	Heavy metal translocating P-type atpase
GER12_RS03555	COG3735	TraB family
GER12_RS03570	COG2223	nitrite transmembrane transporter activity
GER12_RS03575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GER12_RS03575	COG4651	solute:proton antiporter activity
GER12_RS03580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GER12_RS03625	COG2832	Protein of unknown function (DUF454)
GER12_RS03630	COG3923	Primosomal replication protein n
GER12_RS03640	COG5464	transposase or invertase
GER12_RS03645	COG3264	Mechanosensitive ion channel
GER12_RS03645	COG1196	nuclear chromosome segregation
GER12_RS03650	COG1309	transcriptional regulator
GER12_RS03655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GER12_RS03660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GER12_RS03675	COG0110	maltose O-acetyltransferase activity
GER12_RS03695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GER12_RS03705	COG3695	enzyme binding
GER12_RS03710	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GER12_RS03715	COG1946	Acyl-CoA thioesterase
GER12_RS03720	COG0004	ammonium transporteR
GER12_RS03725	COG0347	Belongs to the P(II) protein family
GER12_RS03730	COG1132	(ABC) transporter
GER12_RS03735	COG1132	(ABC) transporter
GER12_RS03740	COG1522	sequence-specific DNA binding
GER12_RS03755	COG4533	DNA binding
GER12_RS03765	COG0824	Thioesterase
GER12_RS03770	COG1555	photosystem II stabilization
GER12_RS03775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GER12_RS03785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GER12_RS03805	COG0271	Belongs to the BolA IbaG family
GER12_RS03810	COG3056	Lipoprotein
GER12_RS03815	COG2223	nitrite transmembrane transporter activity
GER12_RS03820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GER12_RS03825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GER12_RS03830	COG1845	cytochrome c oxidase, subunit III
GER12_RS03835	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GER12_RS03855	COG2814	Major facilitator Superfamily
GER12_RS03885	COG2188	Transcriptional regulator
GER12_RS03920	COG0142	geranyltranstransferase activity
GER12_RS03930	COG0667	Aldo Keto reductase
GER12_RS03935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GER12_RS03955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GER12_RS03955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GER12_RS03965	COG4238	major outer membrane lipoprotein
GER12_RS03995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GER12_RS04005	COG1862	Preprotein translocase
GER12_RS04025	COG0450	alkyl hydroperoxide reductase
GER12_RS04030	COG0366	Alpha amylase catalytic
GER12_RS04045	COG5002	protein histidine kinase activity
GER12_RS04055	COG0420	3'-5' exonuclease activity
GER12_RS04060	COG0419	ATPase involved in DNA repair
GER12_RS04065	COG2814	Major facilitator Superfamily
GER12_RS04070	COG1940	carbohydrate kinase activity
GER12_RS04085	COG4126	flavin adenine dinucleotide binding
GER12_RS04105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GER12_RS04110	COG3706	GGDEF domain
GER12_RS04155	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GER12_RS04160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GER12_RS04175	COG0113	porphobilinogen synthase activity
GER12_RS04210	COG1280	lysine exporter protein (LysE YggA)
GER12_RS04230	COG1294	oxidase, subunit
GER12_RS04235	COG1271	oxidase subunit
GER12_RS04255	COG2814	Major facilitator Superfamily
GER12_RS04265	COG0789	Transcriptional regulator
GER12_RS04320	COG2200	EAL domain
GER12_RS04335	COG3539	Fimbrial protein
GER12_RS04340	COG3121	Chaperone
GER12_RS04345	COG3188	usher protein
GER12_RS04380	COG0179	Fumarylacetoacetate (FAA) hydrolase
GER12_RS04395	COG2814	Major facilitator Superfamily
GER12_RS04420	COG0582	viral genome integration into host DNA
GER12_RS04460	COG2195	Cleaves the N-terminal amino acid of tripeptides
GER12_RS04465	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GER12_RS04470	COG1690	Belongs to the RtcB family
GER12_RS04480	COG3034	peptidoglycan biosynthetic process
GER12_RS04485	COG0121	glutamine amidotransferase
GER12_RS04500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GER12_RS04605	COG3209	COG3209 Rhs family protein
GER12_RS04615	COG3501	Rhs element vgr protein
GER12_RS04755	COG2226	methyltransferase
GER12_RS04765	COG1388	LysM domain
GER12_RS04765	COG0741	lytic transglycosylase activity
GER12_RS04770	COG2226	methyltransferase
GER12_RS04780	COG2814	Major facilitator Superfamily
GER12_RS04785	COG0583	DNA-binding transcription factor activity
GER12_RS04825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GER12_RS04850	COG1720	tRNA m6t6A37 methyltransferase activity
GER12_RS04860	COG3015	lipoprotein NlpE involved in copper resistance
GER12_RS04865	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GER12_RS04880	COG4568	rho-dependent transcription termination
GER12_RS04890	COG0346	lactoylglutathione lyase activity
GER12_RS04955	COG0575	Belongs to the CDS family
GER12_RS05005	COG0477	Major facilitator Superfamily
GER12_RS05015	COG3835	regulator
GER12_RS05040	COG2860	membrane
GER12_RS05050	COG0038	chloride channel
GER12_RS05055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GER12_RS05070	COG3539	Fimbrial protein
GER12_RS05075	COG3539	Fimbrial protein
GER12_RS05080	COG3121	Chaperone
GER12_RS05085	COG3188	usher protein
GER12_RS05100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GER12_RS05105	COG1120	ATPase activity
GER12_RS05110	COG4774	siderophore transport
GER12_RS05115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GER12_RS05120	COG1643	Atp-dependent helicase
GER12_RS05125	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GER12_RS05150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GER12_RS05170	COG0726	polysaccharide deacetylase
GER12_RS05175	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS05195	COG3539	Fimbrial protein
GER12_RS05200	COG0842	Transport permease protein
GER12_RS05205	COG1131	(ABC) transporter
GER12_RS05210	COG0288	reversible hydration of carbon dioxide
GER12_RS05220	COG4993	Dehydrogenase
GER12_RS05245	COG1349	DNA-binding transcription factor activity
GER12_RS05285	COG3064	Membrane
GER12_RS05300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GER12_RS05305	COG0508	dehydrogenase complex catalyzes the overall conversion of
GER12_RS05310	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GER12_RS05325	COG2211	Major facilitator Superfamily
GER12_RS05330	COG3940	Belongs to the glycosyl hydrolase 43 family
GER12_RS05335	COG3725	Membrane protein required for beta-lactamase induction
GER12_RS05350	COG4969	Belongs to the N-Me-Phe pilin family
GER12_RS05355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GER12_RS05360	COG1459	type II secretion system
GER12_RS05390	COG0494	nUDIX hydrolase
GER12_RS05410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GER12_RS05415	COG0849	cell division
GER12_RS05440	COG0772	Belongs to the SEDS family
GER12_RS05455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GER12_RS05465	COG0768	penicillin binding
GER12_RS05560	COG0586	Pfam SNARE associated Golgi protein
GER12_RS05600	COG0417	DNA replication proofreading
GER12_RS05630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GER12_RS05665	COG3119	arylsulfatase activity
GER12_RS05685	COG2271	Major facilitator Superfamily
GER12_RS05690	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GER12_RS05695	COG0644	oxidoreductase
GER12_RS05805	COG0511	ligase activity, forming carbon-carbon bonds
GER12_RS05805	COG5016	pyruvate
GER12_RS05810	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GER12_RS05840	COG1047	Peptidyl-prolyl cis-trans
GER12_RS05855	COG0196	riboflavin kinase activity
GER12_RS05880	COG0583	DNA-binding transcription factor activity
GER12_RS05900	COG0641	radical SAM
GER12_RS05905	COG3119	arylsulfatase activity
GER12_RS05915	COG0737	Belongs to the 5'-nucleotidase family
GER12_RS05930	COG0583	DNA-binding transcription factor activity
GER12_RS05950	COG3121	Chaperone
GER12_RS05955	COG3539	Fimbrial protein
GER12_RS06035	COG4735	regulation of single-species biofilm formation
GER12_RS06040	COG1584	GPR1 FUN34 yaaH family protein
GER12_RS06045	COG0521	Mo-molybdopterin cofactor biosynthetic process
GER12_RS06055	COG1115	amino acid carrier protein
GER12_RS06065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GER12_RS06075	COG0527	aspartate kinase activity
GER12_RS06075	COG0460	homoserine dehydrogenase
GER12_RS06085	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GER12_RS06095	COG0745	RESPONSE REGULATOR receiver
GER12_RS06115	COG3121	Chaperone
GER12_RS06135	COG4452	Inner membrane protein CreD
GER12_RS06140	COG2205	protein histidine kinase activity
GER12_RS06145	COG0745	RESPONSE REGULATOR receiver
GER12_RS06150	COG3045	CreA protein
GER12_RS06155	COG3708	Transcriptional regulator
GER12_RS06155	COG2207	Transcriptional regulator
GER12_RS06180	COG0488	(ABC) transporter
GER12_RS06195	COG0560	Phosphoserine phosphatase
GER12_RS06200	COG3726	membrane protein affecting hemolysin expression
GER12_RS06215	COG3539	Fimbrial protein
GER12_RS06220	COG3121	Chaperone
GER12_RS06225	COG3188	usher protein
GER12_RS06255	COG1328	CTP reductase activity
GER12_RS06260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GER12_RS06265	COG0084	hydrolase, TatD family'
GER12_RS06270	COG4667	esterase of the alpha-beta hydrolase superfamily
GER12_RS06280	COG2823	Periplasmic or secreted lipoprotein
GER12_RS06290	COG1011	Hydrolase
GER12_RS06300	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GER12_RS06330	COG3706	GGDEF domain
GER12_RS06335	COG4114	ferric iron reductase
GER12_RS06340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GER12_RS06345	COG2197	response regulator
GER12_RS06350	COG2197	response regulator
GER12_RS06355	COG2966	Psort location CytoplasmicMembrane, score
GER12_RS06370	COG1484	DNA-dependent DNA replication
GER12_RS06390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GER12_RS06395	COG3716	PTS system mannose fructose sorbose family IID component
GER12_RS06400	COG3715	PTS system
GER12_RS06405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GER12_RS06420	COG0840	transmembrane signaling receptor activity
GER12_RS06425	COG1966	Carbon starvation protein
GER12_RS06430	COG2879	small protein
GER12_RS06435	COG0523	cobalamin synthesis protein
GER12_RS06450	COG1715	Restriction endonuclease
GER12_RS06455	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GER12_RS06490	COG1012	belongs to the aldehyde dehydrogenase family
GER12_RS06495	COG5464	transposase or invertase
GER12_RS06505	COG2733	membrane
GER12_RS06510	COG0477	Major facilitator Superfamily
GER12_RS06515	COG3366	ferrous iron transmembrane transporter activity
GER12_RS06520	COG0700	Nucleoside recognition
GER12_RS06525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GER12_RS06530	COG0583	DNA-binding transcription factor activity
GER12_RS06550	COG2186	Transcriptional regulator
GER12_RS06555	COG0412	Dienelactone hydrolase
GER12_RS06585	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GER12_RS06600	COG0210	DNA helicase
GER12_RS06620	COG3409	Peptidoglycan-binding domain 1 protein
GER12_RS06620	COG3429	Glucose-6-phosphate dehydrogenase subunit
GER12_RS06720	COG0582	viral genome integration into host DNA
GER12_RS06730	COG1064	alcohol dehydrogenase
GER12_RS06735	COG3265	gluconokinase activity
GER12_RS06740	COG1063	alcohol dehydrogenase
GER12_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
GER12_RS06750	COG2610	gluconate transmembrane transporter activity
GER12_RS06755	COG1609	Transcriptional regulator
GER12_RS06760	COG0795	lipopolysaccharide-transporting ATPase activity
GER12_RS06765	COG0795	lipopolysaccharide-transporting ATPase activity
GER12_RS06775	COG2927	DNA polymerase III (CHI subunit)
GER12_RS06815	COG2731	YhcH YjgK YiaL family protein
GER12_RS06835	COG1288	antiporter activity
GER12_RS06840	COG1438	arginine binding
GER12_RS06890	COG1263	PTS System
GER12_RS06890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GER12_RS06895	COG0366	Alpha amylase catalytic
GER12_RS06910	COG2026	Addiction module toxin, RelE StbE family
GER12_RS06915	COG3077	Addiction module antitoxin, RelB DinJ family
GER12_RS06920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS06920	COG3711	transcriptional antiterminator
GER12_RS06935	COG3964	amidohydrolase
GER12_RS06970	COG0312	modulator of DNA gyrase
GER12_RS06980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GER12_RS06995	COG3964	amidohydrolase
GER12_RS07000	COG2271	Major facilitator Superfamily
GER12_RS07005	COG2105	PFAM AIG2 family protein
GER12_RS07025	COG1253	flavin adenine dinucleotide binding
GER12_RS07035	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GER12_RS07050	COG1733	regulation of RNA biosynthetic process
GER12_RS07055	COG0702	epimerase
GER12_RS07060	COG0697	spore germination
GER12_RS07070	COG1113	amino acid transport
GER12_RS07075	COG0545	Peptidyl-prolyl cis-trans isomerase
GER12_RS07080	COG3061	Opacity-associated protein A
GER12_RS07095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GER12_RS07145	COG3037	sugar-specific permease SgaT UlaA
GER12_RS07160	COG1073	alpha beta
GER12_RS07165	COG3650	response to hydrogen peroxide
GER12_RS07175	COG1960	acyl-CoA dehydrogenase activity
GER12_RS07180	COG0754	glutathionylspermidine amidase activity
GER12_RS07185	COG5463	Belongs to the UPF0441 family
GER12_RS07190	COG3766	membrane
GER12_RS07205	COG1842	Phage shock protein A
GER12_RS07210	COG3789	protein conserved in bacteria
GER12_RS07220	COG0557	exoribonuclease II activity
GER12_RS07235	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GER12_RS07240	COG0330	HflC and HflK could
GER12_RS07245	COG0330	HflC and HflK could
GER12_RS07250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GER12_RS07275	COG0802	atpase or kinase
GER12_RS07280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GER12_RS07280	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GER12_RS07305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GER12_RS07325	COG1511	domain protein
GER12_RS07325	COG3264	Mechanosensitive ion channel
GER12_RS07345	COG1053	succinate dehydrogenase
GER12_RS07350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GER12_RS07380	COG5510	response to toxic substance
GER12_RS07420	COG0531	amino acid
GER12_RS07425	COG3030	protein affecting phage T7 exclusion by the F plasmid
GER12_RS07430	COG1027	Aspartate ammonia-lyase
GER12_RS07435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GER12_RS07450	COG1309	transcriptional regulator
GER12_RS07465	COG0671	phosphoesterase, PA-phosphatase related
GER12_RS07560	COG2197	response regulator
GER12_RS07585	COG3381	protein complex oligomerization
GER12_RS07590	COG3302	dmso reductase anchor subunit
GER12_RS07595	COG0437	4 iron, 4 sulfur cluster binding
GER12_RS07600	COG0243	molybdopterin cofactor binding
GER12_RS07605	COG3290	protein histidine kinase activity
GER12_RS07610	COG4565	transcriptional regulatory protein
GER12_RS07620	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GER12_RS07625	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GER12_RS07625	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GER12_RS07640	COG2169	Transcriptional regulator
GER12_RS07645	COG1982	Orn Lys Arg decarboxylase major
GER12_RS07650	COG2207	Transcriptional regulator
GER12_RS07655	COG0531	amino acid
GER12_RS07685	COG2824	Alkylphosphonate utilization operon protein PhnA
GER12_RS07690	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GER12_RS07710	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GER12_RS07715	COG1301	dicarboxylic acid transport
GER12_RS07720	COG4235	cytochrome complex assembly
GER12_RS07725	COG3088	subunit of a heme lyase
GER12_RS07730	COG1138	Cytochrome C-type biogenesis protein
GER12_RS07735	COG3301	Polysulphide reductase, NrfD
GER12_RS07740	COG0437	4 iron, 4 sulfur cluster binding
GER12_RS07745	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GER12_RS07755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GER12_RS07760	COG3162	membrane
GER12_RS07770	COG1346	cytolysis
GER12_RS07775	COG1380	Effector of murein hydrolase LrgA
GER12_RS07780	COG0583	DNA-binding transcription factor activity
GER12_RS07785	COG0025	NhaP-type Na H and K H
GER12_RS07790	COG2252	PERMEase
GER12_RS07810	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GER12_RS07870	COG2315	Protein conserved in bacteria
GER12_RS07920	COG0735	belongs to the Fur family
GER12_RS07935	COG0534	Mate efflux family protein
GER12_RS07945	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GER12_RS07990	COG3833	ABC-type maltose transport systems, permease component
GER12_RS08000	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GER12_RS08025	COG0527	aspartate kinase activity
GER12_RS08105	COG2246	polysaccharide biosynthetic process
GER12_RS08135	COG5301	cellulose 1,4-beta-cellobiosidase activity
GER12_RS08140	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GER12_RS08155	COG0561	phosphatase activity
GER12_RS08160	COG1349	DNA-binding transcription factor activity
GER12_RS08175	COG3122	Protein conserved in bacteria
GER12_RS08220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GER12_RS08260	COG0151	Belongs to the GarS family
GER12_RS08325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GER12_RS08330	COG2104	thiamine diphosphate biosynthetic process
GER12_RS08390	COG0250	Participates in transcription elongation, termination and antitermination
GER12_RS08500	COG0583	DNA-binding transcription factor activity
GER12_RS08535	COG2207	Transcriptional regulator
GER12_RS08545	COG0371	Dehydrogenase
GER12_RS08550	COG3738	Protein conserved in bacteria
GER12_RS08565	COG0737	Belongs to the 5'-nucleotidase family
GER12_RS08580	COG0668	transmembrane transport
GER12_RS08585	COG0460	homoserine dehydrogenase
GER12_RS08585	COG0527	aspartate kinase activity
GER12_RS08590	COG0626	cystathionine gamma-synthase activity
GER12_RS08615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GER12_RS08620	COG1609	Transcriptional regulator
GER12_RS08625	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GER12_RS08640	COG1575	Belongs to the MenA family. Type 1 subfamily
GER12_RS08655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GER12_RS08665	COG1494	fructose-1,6-bisphosphatase
GER12_RS08675	COG3152	Membrane
GER12_RS08730	COG1070	Carbohydrate kinase
GER12_RS08740	COG2134	cdp-diacylglycerol pyrophosphatase
GER12_RS08750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GER12_RS08760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GER12_RS08765	COG2211	Major facilitator Superfamily
GER12_RS08790	COG3678	ATP-independent chaperone mediated protein folding
GER12_RS08795	COG0745	RESPONSE REGULATOR receiver
GER12_RS08800	COG2205	protein histidine kinase activity
GER12_RS08810	COG2258	MOSC domain
GER12_RS08815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GER12_RS08825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GER12_RS08870	COG1454	alcohol dehydrogenase
GER12_RS08885	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GER12_RS08915	COG0437	4 iron, 4 sulfur cluster binding
GER12_RS08920	COG2864	formate dehydrogenase
GER12_RS08935	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GER12_RS08945	COG4680	protein conserved in bacteria
GER12_RS08950	COG5499	transcription regulator containing HTH domain
GER12_RS08955	COG0456	acetyltransferase
GER12_RS08970	COG1011	Hydrolase
GER12_RS08975	COG1349	DNA-binding transcription factor activity
GER12_RS08980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GER12_RS09000	COG2017	converts alpha-aldose to the beta-anomer
GER12_RS09005	COG1501	Belongs to the glycosyl hydrolase 31 family
GER12_RS09080	COG0204	Acyl-transferase
GER12_RS09095	COG3084	Protein conserved in bacteria
GER12_RS09100	COG0746	molybdenum cofactor guanylyltransferase activity
GER12_RS09105	COG1763	Mo-molybdopterin cofactor biosynthetic process
GER12_RS09145	COG1739	Uncharacterized protein family UPF0029
GER12_RS09190	COG0805	protein transport
GER12_RS09235	COG0641	radical SAM
GER12_RS09255	COG0561	phosphatase activity
GER12_RS09260	COG2267	carboxylic ester hydrolase activity
GER12_RS09270	COG1280	lysine exporter protein (LysE YggA)
GER12_RS09315	COG1011	Hydrolase
GER12_RS09385	COG2959	enzyme of heme biosynthesis
GER12_RS09390	COG3071	HemY protein
GER12_RS09435	COG2244	polysaccharide biosynthetic process
GER12_RS09440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GER12_RS09445	COG0456	acetyltransferase
GER12_RS09450	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GER12_RS09455	COG1088	dTDP-glucose 4,6-dehydratase activity
GER12_RS09460	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GER12_RS09490	COG3118	belongs to the thioredoxin family
GER12_RS09510	COG3201	nicotinamide mononucleotide transporter
GER12_RS09555	COG3978	acetolactate synthase activity
GER12_RS09615	COG2186	Transcriptional regulator
GER12_RS09620	COG0477	Major facilitator Superfamily
GER12_RS09625	COG1609	Transcriptional regulator
GER12_RS09630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GER12_RS09640	COG1172	Belongs to the binding-protein-dependent transport system permease family
GER12_RS09675	COG1522	sequence-specific DNA binding
GER12_RS09680	COG0716	FMN binding
GER12_RS09695	COG3312	ion transport
GER12_RS09755	COG4533	DNA binding
GER12_RS09760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GER12_RS09765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GER12_RS09765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GER12_RS09765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GER12_RS09770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GER12_RS09775	COG0573	inorganic phosphate transmembrane transporter activity
GER12_RS09780	COG0581	inorganic phosphate transmembrane transporter activity
GER12_RS09790	COG0704	Plays a role in the regulation of phosphate uptake
GER12_RS09795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GER12_RS09800	COG2252	PERMEase
GER12_RS09805	COG0431	NADPH-dependent FMN reductase
GER12_RS09810	COG2091	lysine biosynthetic process via aminoadipic acid
GER12_RS09900	COG4948	Mandelate Racemase Muconate Lactonizing
GER12_RS09910	COG0561	phosphatase activity
GER12_RS09915	COG2186	Transcriptional regulator
GER12_RS09920	COG3734	2-keto-3-deoxy-galactonokinase
GER12_RS09925	COG0800	Aldolase
GER12_RS09935	COG2271	Major facilitator Superfamily
GER12_RS09940	COG0784	Response regulator, receiver
GER12_RS09940	COG2198	Histidine kinase
GER12_RS09940	COG2205	protein histidine kinase activity
GER12_RS09945	COG1879	ABC-type sugar transport system periplasmic component
GER12_RS09950	COG0745	RESPONSE REGULATOR receiver
GER12_RS09955	COG3005	denitrification pathway
GER12_RS09970	COG1858	cytochrome C peroxidase
GER12_RS09980	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GER12_RS09985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GER12_RS09990	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GER12_RS10000	COG1138	Cytochrome C-type biogenesis protein
GER12_RS10010	COG4235	cytochrome complex assembly
GER12_RS10010	COG3088	subunit of a heme lyase
GER12_RS10015	COG0823	Involved in the tonB-independent uptake of proteins
GER12_RS10020	COG5645	(Lipo)protein
GER12_RS10030	COG0071	Belongs to the small heat shock protein (HSP20) family
GER12_RS10040	COG2149	membrane
GER12_RS10050	COG0641	radical SAM
GER12_RS10060	COG2610	gluconate transmembrane transporter activity
GER12_RS10065	COG0583	DNA-binding transcription factor activity
GER12_RS10075	COG2814	Major facilitator Superfamily
GER12_RS10100	COG0028	Belongs to the TPP enzyme family
GER12_RS10105	COG0440	acetolactate synthase activity
GER12_RS10110	COG1349	DNA-binding transcription factor activity
GER12_RS10120	COG0738	Major facilitator superfamily
GER12_RS10155	COG2188	Transcriptional regulator
GER12_RS10160	COG3711	transcriptional antiterminator
GER12_RS10160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS10165	COG3414	Phosphotransferase system galactitol-specific IIB component
GER12_RS10170	COG3775	system Galactitol-specific IIC component
GER12_RS10205	COG2723	6-phospho-beta-galactosidase activity
GER12_RS10225	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS10225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GER12_RS10230	COG3715	PTS system
GER12_RS10235	COG3716	PTS system mannose fructose sorbose family IID component
GER12_RS10250	COG5464	transposase or invertase
GER12_RS10280	COG1335	isochorismatase
GER12_RS10290	COG3710	Transcriptional regulator
GER12_RS10305	COG2771	luxR family
GER12_RS10320	COG3121	Chaperone
GER12_RS10325	COG3188	usher protein
GER12_RS10335	COG3539	Fimbrial protein
GER12_RS10345	COG3539	Fimbrial protein
GER12_RS10360	COG2211	Major facilitator Superfamily
GER12_RS10365	COG1501	Belongs to the glycosyl hydrolase 31 family
GER12_RS10370	COG2982	Protein involved in outer membrane biogenesis
GER12_RS10375	COG2233	PERMEase
GER12_RS10380	COG0786	glutamate:sodium symporter activity
GER12_RS10385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GER12_RS10390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GER12_RS10395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GER12_RS10415	COG2860	membrane
GER12_RS10425	COG0583	DNA-binding transcription factor activity
GER12_RS10430	COG1561	YicC-like family, N-terminal region
GER12_RS10455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GER12_RS10485	COG1519	Transferase
GER12_RS10490	COG0859	PFAM glycosyl transferase family 9
GER12_RS10495	COG0438	transferase activity, transferring glycosyl groups
GER12_RS10570	COG1216	Glycosyl transferase, family 2
GER12_RS10575	COG2861	carbohydrate metabolic process
GER12_RS10580	COG4942	peptidase
GER12_RS10590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GER12_RS10595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GER12_RS10615	COG2271	Major facilitator Superfamily
GER12_RS10625	COG1609	Transcriptional regulator
GER12_RS10630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GER12_RS10640	COG2186	Transcriptional regulator
GER12_RS10670	COG3722	fumarate hydratase activity
GER12_RS10680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS10680	COG2213	PTS system mannitol-specific
GER12_RS10685	COG0625	glutathione transferase activity
GER12_RS10695	COG3276	selenocysteine insertion sequence binding
GER12_RS10700	COG1940	carbohydrate kinase activity
GER12_RS10705	COG1012	belongs to the aldehyde dehydrogenase family
GER12_RS10720	COG0235	Class ii aldolase
GER12_RS10725	COG3623	hexulose-6-phosphate isomerase
GER12_RS10730	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GER12_RS10735	COG1070	Carbohydrate kinase
GER12_RS10740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GER12_RS10745	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GER12_RS10750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GER12_RS10760	COG2731	YhcH YjgK YiaL family protein
GER12_RS10770	COG1414	Transcriptional regulator
GER12_RS10775	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GER12_RS10780	COG3977	Valine--pyruvate aminotransferase
GER12_RS10785	COG0366	Alpha amylase catalytic
GER12_RS10790	COG2992	FlgJ-related protein
GER12_RS10795	COG1609	Transcriptional regulator
GER12_RS10795	COG2207	Transcriptional regulator
GER12_RS10805	COG1070	Carbohydrate kinase
GER12_RS10810	COG4682	membrane
GER12_RS10815	COG3274	enterobacterial common antigen metabolic process
GER12_RS10835	COG2801	Transposase and inactivated derivatives
GER12_RS10860	COG1278	Cold shock
GER12_RS10865	COG2944	sequence-specific DNA binding
GER12_RS10880	COG2885	chlorophyll binding
GER12_RS10885	COG0243	molybdopterin cofactor binding
GER12_RS10890	COG0456	acetyltransferase
GER12_RS10895	COG2818	Glycosylase
GER12_RS10900	COG5571	outer membrane autotransporter
GER12_RS10925	COG1609	Transcriptional regulator
GER12_RS10940	COG0747	negative chemotaxis
GER12_RS10945	COG0601	transmembrane transport
GER12_RS10950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GER12_RS10955	COG0444	Belongs to the ABC transporter superfamily
GER12_RS10960	COG4608	Belongs to the ABC transporter superfamily
GER12_RS10965	COG0814	amino acid
GER12_RS11025	COG2199	diguanylate cyclase activity
GER12_RS11025	COG2200	EAL domain
GER12_RS11040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GER12_RS11045	COG2200	EAL domain
GER12_RS11050	COG2982	Protein involved in outer membrane biogenesis
GER12_RS11055	COG0477	Major facilitator Superfamily
GER12_RS11060	COG1295	ribonuclease BN
GER12_RS11065	COG0583	DNA-binding transcription factor activity
GER12_RS11070	COG2197	response regulator
GER12_RS11090	COG2188	Transcriptional regulator
GER12_RS11095	COG2222	sugar isomerase
GER12_RS11100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GER12_RS11105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GER12_RS11115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GER12_RS11120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GER12_RS11125	COG0671	phosphoesterase, PA-phosphatase related
GER12_RS11155	COG0306	phosphate transporter
GER12_RS11160	COG2081	HI0933 family
GER12_RS11165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GER12_RS11170	COG0842	Transport permease protein
GER12_RS11170	COG1129	ABC transporter
GER12_RS11175	COG0842	Transport permease protein
GER12_RS11185	COG2091	lysine biosynthetic process via aminoadipic acid
GER12_RS11190	COG0628	permease
GER12_RS11205	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GER12_RS11225	COG3714	YhhN family
GER12_RS11235	COG3776	membrane
GER12_RS11240	COG0742	ribosomal rna small subunit methyltransferase
GER12_RS11245	COG0552	protein localization to endoplasmic reticulum
GER12_RS11250	COG2884	Cell division ATP-binding protein ftsE
GER12_RS11255	COG2177	Part of the ABC transporter FtsEX involved in
GER12_RS11335	COG0584	glycerophosphoryl diester phosphodiesterase
GER12_RS11345	COG0405	Gamma-glutamyltransferase
GER12_RS11350	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GER12_RS11365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GER12_RS11370	COG1247	-acetyltransferase
GER12_RS11375	COG0673	inositol 2-dehydrogenase activity
GER12_RS11380	COG1741	Belongs to the pirin family
GER12_RS11385	COG1609	Transcriptional regulator
GER12_RS11390	COG3265	gluconokinase activity
GER12_RS11395	COG2610	gluconate transmembrane transporter activity
GER12_RS11430	COG0058	SHG alpha-glucan phosphorylase activity
GER12_RS11435	COG1414	Transcriptional regulator
GER12_RS11440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GER12_RS11445	COG0129	dihydroxy-acid dehydratase activity
GER12_RS11455	COG0371	Dehydrogenase
GER12_RS11470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GER12_RS11485	COG1349	DNA-binding transcription factor activity
GER12_RS11495	COG0058	SHG alpha-glucan phosphorylase activity
GER12_RS11500	COG1640	4-alpha-glucanotransferase
GER12_RS11505	COG2610	gluconate transmembrane transporter activity
GER12_RS11525	COG5464	transposase or invertase
GER12_RS11540	COG1918	ferrous iron import across plasma membrane
GER12_RS11545	COG2183	response to ionizing radiation
GER12_RS11550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GER12_RS11555	COG0745	RESPONSE REGULATOR receiver
GER12_RS11570	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GER12_RS11580	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GER12_RS11585	COG1011	Hydrolase
GER12_RS11595	COG0494	nUDIX hydrolase
GER12_RS11600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GER12_RS11605	COG4972	Pilus assembly protein
GER12_RS11610	COG3166	PFAM Fimbrial assembly family protein
GER12_RS11625	COG4796	Type ii and iii secretion system protein
GER12_RS11640	COG3266	domain, Protein
GER12_RS11645	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GER12_RS11650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GER12_RS11690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GER12_RS11725	COG1289	transmembrane transporter activity
GER12_RS11735	COG1765	OsmC-like protein
GER12_RS11740	COG3954	Phosphoribulokinase
GER12_RS11750	COG0429	hydrolase of the alpha beta-hydrolase fold
GER12_RS11765	COG0488	(ABC) transporter
GER12_RS11780	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GER12_RS11785	COG1047	Peptidyl-prolyl cis-trans
GER12_RS11795	COG0545	Peptidyl-prolyl cis-trans isomerase
GER12_RS11800	COG2964	Protein conserved in bacteria
GER12_RS11855	COG0051	transcription antitermination factor activity, RNA binding
GER12_RS11880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GER12_RS11960	COG0201	protein transport
GER12_RS12000	COG0789	Transcriptional regulator
GER12_RS12005	COG3036	rescue of stalled ribosome
GER12_RS12035	COG0758	DNA mediated transformation
GER12_RS12045	COG0551	DNA topoisomerase type I activity
GER12_RS12065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GER12_RS12110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GER12_RS12115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GER12_RS12120	COG1309	transcriptional regulator
GER12_RS12135	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GER12_RS12155	COG4145	pantothenate transmembrane transporter activity
GER12_RS12160	COG3924	membrane
GER12_RS12165	COG0439	Biotin carboxylase
GER12_RS12170	COG0511	ligase activity, forming carbon-carbon bonds
GER12_RS12185	COG0604	alcohol dehydrogenase
GER12_RS12190	COG2199	diguanylate cyclase activity
GER12_RS12190	COG2200	EAL domain
GER12_RS12195	COG1077	Cell shape determining protein MreB Mrl
GER12_RS12200	COG1792	Involved in formation and maintenance of cell shape
GER12_RS12205	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GER12_RS12215	COG1530	ribonuclease E activity
GER12_RS12220	COG3164	Protein of unknown function
GER12_RS12225	COG0312	modulator of DNA gyrase
GER12_RS12230	COG0583	DNA-binding transcription factor activity
GER12_RS12250	COG2732	(Barnase) inhibitor
GER12_RS12275	COG2188	Transcriptional regulator
GER12_RS12285	COG0471	metal ion transport
GER12_RS12290	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GER12_RS12295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GER12_RS12310	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GER12_RS12325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GER12_RS12330	COG3105	Protein conserved in bacteria
GER12_RS12335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GER12_RS12355	COG0625	glutathione transferase activity
GER12_RS12360	COG2969	positive regulation of protein catabolic process
GER12_RS12390	COG2731	YhcH YjgK YiaL family protein
GER12_RS12395	COG0402	S-adenosylhomocysteine deaminase activity
GER12_RS12400	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GER12_RS12405	COG4804	nuclease activity
GER12_RS12410	COG0493	'glutamate synthase
GER12_RS12415	COG0070	glutamate synthase
GER12_RS12415	COG0069	glutamate synthase activity
GER12_RS12415	COG0067	glutamate synthase
GER12_RS12420	COG1242	4 iron, 4 sulfur cluster binding
GER12_RS12425	COG2198	Histidine kinase
GER12_RS12425	COG0784	Response regulator, receiver
GER12_RS12425	COG5002	protein histidine kinase activity
GER12_RS12430	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GER12_RS12435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GER12_RS12440	COG0515	serine threonine protein kinase
GER12_RS12445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS12470	COG1137	ATPase activity
GER12_RS12475	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GER12_RS12480	COG3117	lipopolysaccharide transmembrane transporter activity
GER12_RS12495	COG0530	calcium, potassium:sodium antiporter activity
GER12_RS12500	COG1127	ABC transporter
GER12_RS12505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GER12_RS12510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GER12_RS12515	COG2854	intermembrane phospholipid transfer
GER12_RS12520	COG3113	response to antibiotic
GER12_RS12525	COG5007	Belongs to the BolA IbaG family
GER12_RS12535	COG3423	Transcriptional regulator
GER12_RS12540	COG0142	geranyltranstransferase activity
GER12_RS12555	COG0697	spore germination
GER12_RS12565	COG2027	D-alanyl-D-alanine carboxypeptidase
GER12_RS12575	COG1534	Rna-binding protein
GER12_RS12590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GER12_RS12600	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GER12_RS12670	COG0513	Belongs to the DEAD box helicase family
GER12_RS12675	COG0814	amino acid
GER12_RS12680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GER12_RS12685	COG0826	peptidase U32
GER12_RS12690	COG0826	peptidase U32
GER12_RS12695	COG3154	lipid carrier protein
GER12_RS12700	COG3153	acetyltransferase
GER12_RS12715	COG0693	protein deglycase activity
GER12_RS12720	COG0702	epimerase
GER12_RS12725	COG2823	Periplasmic or secreted lipoprotein
GER12_RS12745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GER12_RS12755	COG1063	alcohol dehydrogenase
GER12_RS12760	COG3775	system Galactitol-specific IIC component
GER12_RS12765	COG3414	Phosphotransferase system galactitol-specific IIB component
GER12_RS12770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS12785	COG2721	sulfolactate sulfo-lyase activity
GER12_RS12795	COG2084	Dehydrogenase
GER12_RS12800	COG1929	Belongs to the glycerate kinase type-1 family
GER12_RS12810	COG0583	DNA-binding transcription factor activity
GER12_RS12830	COG1882	Formate acetyltransferase
GER12_RS12835	COG1760	l-serine dehydratase
GER12_RS12840	COG0814	amino acid
GER12_RS12855	COG1741	Belongs to the pirin family
GER12_RS12860	COG0583	DNA-binding transcription factor activity
GER12_RS12865	COG3152	Membrane
GER12_RS12870	COG0435	Glutathione S-transferase
GER12_RS12875	COG2259	Doxx family
GER12_RS12885	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GER12_RS12890	COG4575	ribosome binding
GER12_RS12895	COG1422	Protein of unknown function (DUF1090)
GER12_RS12905	COG0586	Pfam SNARE associated Golgi protein
GER12_RS12920	COG0673	inositol 2-dehydrogenase activity
GER12_RS12925	COG2949	membrane
GER12_RS12930	COG1451	nucleotide metabolic process
GER12_RS12940	COG1902	pentaerythritol trinitrate reductase activity
GER12_RS12940	COG0446	pyridine nucleotide-disulphide oxidoreductase
GER12_RS12950	COG0840	transmembrane signaling receptor activity
GER12_RS12955	COG0840	transmembrane signaling receptor activity
GER12_RS12960	COG1695	Transcriptional regulator
GER12_RS12965	COG2375	cellular response to nickel ion
GER12_RS12990	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GER12_RS13015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GER12_RS13030	COG4991	sh3 domain protein
GER12_RS13035	COG3025	triphosphatase activity
GER12_RS13055	COG2268	Band 7 protein
GER12_RS13060	COG1585	Membrane protein implicated in regulation of membrane protease activity
GER12_RS13100	COG3384	dioxygenase
GER12_RS13105	COG0754	glutathionylspermidine amidase activity
GER12_RS13120	COG0494	nUDIX hydrolase
GER12_RS13125	COG3151	Protein conserved in bacteria
GER12_RS13130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GER12_RS13135	COG3150	esterase
GER12_RS13145	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GER12_RS13150	COG2249	NAD(P)H dehydrogenase (quinone) activity
GER12_RS13165	COG3111	PFAM Bacterial OB fold (BOF) protein
GER12_RS13170	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GER12_RS13220	COG0471	metal ion transport
GER12_RS13230	COG1979	alcohol dehydrogenase
GER12_RS13235	COG2207	Transcriptional regulator
GER12_RS13255	COG0848	biopolymer transport protein
GER12_RS13260	COG1028	Short-chain dehydrogenase reductase Sdr
GER12_RS13285	COG0840	transmembrane signaling receptor activity
GER12_RS13295	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GER12_RS13300	COG0437	4 iron, 4 sulfur cluster binding
GER12_RS13305	COG5557	Pfam Polysulphide reductase, NrfD
GER12_RS13310	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GER12_RS13315	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GER12_RS13320	COG1773	rubredoxin
GER12_RS13330	COG0298	carbon dioxide binding
GER12_RS13345	COG0625	glutathione transferase activity
GER12_RS13350	COG0754	glutathionylspermidine amidase activity
GER12_RS13365	COG0246	Mannitol dehydrogenase
GER12_RS13375	COG2271	Major facilitator Superfamily
GER12_RS13400	COG1012	belongs to the aldehyde dehydrogenase family
GER12_RS13405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GER12_RS13415	COG0531	amino acid
GER12_RS13445	COG2301	Belongs to the HpcH HpaI aldolase family
GER12_RS13450	COG2030	dehydratase
GER12_RS13455	COG0427	acetyl-CoA hydrolase
GER12_RS13470	COG1811	Na channel or pump
GER12_RS13475	COG1982	Orn Lys Arg decarboxylase major
GER12_RS13480	COG2211	Major facilitator Superfamily
GER12_RS13505	COG3171	Protein conserved in bacteria
GER12_RS13515	COG0252	asparaginase activity
GER12_RS13525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GER12_RS13540	COG0762	integral membrane protein
GER12_RS13545	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GER12_RS13550	COG2805	Type II/IV secretion system protein
GER12_RS13575	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GER12_RS13580	COG2356	endonuclease I
GER12_RS13590	COG2814	Major facilitator Superfamily
GER12_RS13615	COG1166	arginine decarboxylase activity
GER12_RS13625	COG2186	Transcriptional regulator
GER12_RS13635	COG0246	Mannitol dehydrogenase
GER12_RS13640	COG1063	alcohol dehydrogenase
GER12_RS13645	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GER12_RS13650	COG2731	YhcH YjgK YiaL family protein
GER12_RS13655	COG2267	carboxylic ester hydrolase activity
GER12_RS13665	COG0501	Belongs to the peptidase M48B family
GER12_RS13670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GER12_RS13675	COG1122	ATPase activity
GER12_RS13680	COG1122	ATPase activity
GER12_RS13710	COG0191	fructose-bisphosphate aldolase activity
GER12_RS13715	COG0668	transmembrane transport
GER12_RS13725	COG2968	Membrane
GER12_RS13740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GER12_RS13745	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GER12_RS13765	COG0006	proline dipeptidase activity
GER12_RS13770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GER12_RS13775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GER12_RS13800	COG2723	6-phospho-beta-galactosidase activity
GER12_RS13810	COG1272	protein, Hemolysin III
GER12_RS13865	COG4942	peptidase
GER12_RS13905	COG3188	usher protein
GER12_RS13940	COG0814	amino acid
GER12_RS13955	COG0183	Belongs to the thiolase family
GER12_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
GER12_RS13970	COG2814	Major facilitator Superfamily
GER12_RS13975	COG1794	racemase activity, acting on amino acids and derivatives
GER12_RS13980	COG0583	DNA-binding transcription factor activity
GER12_RS13990	COG1609	Transcriptional regulator
GER12_RS14010	COG0667	Aldo Keto reductase
GER12_RS14020	COG0861	Integral membrane protein TerC family
GER12_RS14050	COG2165	general secretion pathway protein
GER12_RS14055	COG4795	General secretion pathway protein
GER12_RS14065	COG4967	type IV pilus modification protein PilV
GER12_RS14070	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GER12_RS14075	COG1025	Belongs to the peptidase M16 family
GER12_RS14080	COG1074	ATP-dependent DNA helicase activity
GER12_RS14085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GER12_RS14095	COG0860	N-Acetylmuramoyl-L-alanine amidase
GER12_RS14110	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GER12_RS14115	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GER12_RS14120	COG2962	Rard protein
GER12_RS14125	COG2166	iron-sulfur cluster assembly
GER12_RS14130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GER12_RS14140	COG0583	DNA-binding transcription factor activity
GER12_RS14145	COG2363	Small membrane protein
GER12_RS14155	COG1349	DNA-binding transcription factor activity
GER12_RS14175	COG0738	Major facilitator superfamily
GER12_RS14180	COG0235	Class ii aldolase
GER12_RS14185	COG1454	alcohol dehydrogenase
GER12_RS14195	COG1760	l-serine dehydratase
GER12_RS14200	COG0814	amino acid
GER12_RS14205	COG1611	Belongs to the LOG family
GER12_RS14225	COG3098	single-species biofilm formation
GER12_RS14235	COG0716	FMN binding
GER12_RS14240	COG2271	Major facilitator Superfamily
GER12_RS14245	COG4948	Mandelate Racemase Muconate Lactonizing
GER12_RS14250	COG4948	Mandelate Racemase Muconate Lactonizing
GER12_RS14255	COG1929	Belongs to the glycerate kinase type-1 family
GER12_RS14260	COG4999	Histidine kinase
GER12_RS14260	COG2205	protein histidine kinase activity
GER12_RS14260	COG3437	response regulator, receiver
GER12_RS14260	COG3850	Histidine kinase
GER12_RS14270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GER12_RS14275	COG3609	addiction module antidote protein, CC2985 family
GER12_RS14285	COG3956	TIGRFAM MazG family protein
GER12_RS14300	COG0602	queuosine metabolic process
GER12_RS14305	COG0321	lipoyl(octanoyl) transferase activity
GER12_RS14305	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GER12_RS14310	COG0720	synthase
GER12_RS14335	COG1203	CRISPR-associated helicase, Cas3
GER12_RS14350	COG1857	crispr-associated protein
GER12_RS14365	COG1518	maintenance of DNA repeat elements
GER12_RS14370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GER12_RS14375	COG2234	aminopeptidase activity
GER12_RS14430	COG1388	LysM domain
GER12_RS14430	COG4942	peptidase
GER12_RS14445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GER12_RS14450	COG0163	prenyltransferase activity
GER12_RS14460	COG1349	DNA-binding transcription factor activity
GER12_RS14465	COG2084	Dehydrogenase
GER12_RS14475	COG0235	Class ii aldolase
GER12_RS14480	COG3622	Belongs to the hyi family
GER12_RS14485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GER12_RS14490	COG2610	gluconate transmembrane transporter activity
GER12_RS14500	COG0477	Major facilitator Superfamily
GER12_RS14565	COG2207	Transcriptional regulator
GER12_RS14655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GER12_RS14740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GER12_RS14745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GER12_RS14750	COG1121	(ABC) transporter
GER12_RS14770	COG0309	Hydrogenase expression formation protein (HypE)
GER12_RS14775	COG0409	Hydrogenase expression formation protein
GER12_RS14780	COG0298	carbon dioxide binding
GER12_RS14785	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GER12_RS14800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GER12_RS14805	COG0651	ATP synthesis coupled electron transport
GER12_RS14810	COG0650	Formate hydrogenlyase subunit 4
GER12_RS14815	COG3261	NADH dehydrogenase
GER12_RS14815	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GER12_RS14820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GER12_RS14825	COG3260	NADH ubiquinone oxidoreductase 20
GER12_RS14835	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GER12_RS14845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GER12_RS14850	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GER12_RS14870	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GER12_RS14870	COG0517	IMP dehydrogenase activity
GER12_RS14875	COG1349	DNA-binding transcription factor activity
GER12_RS14880	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS14885	COG1028	Short-chain dehydrogenase reductase Sdr
GER12_RS14890	COG3731	PTS system glucitol sorbitol-specific IIA component
GER12_RS14895	COG3732	PTS system glucitol sorbitol-specific
GER12_RS14900	COG3730	PTS system glucitol sorbitol-specific
GER12_RS14905	COG2951	lytic endotransglycosylase activity
GER12_RS14910	COG1546	Belongs to the CinA family
GER12_RS14930	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GER12_RS14960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GER12_RS14965	COG1238	metal cluster binding
GER12_RS14985	COG2814	Major facilitator Superfamily
GER12_RS14990	COG1566	PFAM secretion protein HlyD family protein
GER12_RS14995	COG1846	Transcriptional regulator
GER12_RS15000	COG2814	Major facilitator Superfamily
GER12_RS15040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GER12_RS15050	COG4575	ribosome binding
GER12_RS15075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GER12_RS15080	COG0640	Transcriptional regulator
GER12_RS15085	COG0401	homolog of Blt101
GER12_RS15090	COG1652	LysM domain
GER12_RS15095	COG1802	Transcriptional regulator
GER12_RS15100	COG1113	amino acid transport
GER12_RS15105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GER12_RS15110	COG1012	belongs to the aldehyde dehydrogenase family
GER12_RS15115	COG0579	oxidoreductase
GER12_RS15145	COG0642	Histidine kinase
GER12_RS15150	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GER12_RS15160	COG2990	Protein conserved in bacteria
GER12_RS15180	COG2819	hydrolase of the alpha beta superfamily
GER12_RS15275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GER12_RS15300	COG2867	negative regulation of translational initiation
GER12_RS15315	COG0497	DNA recombination
GER12_RS15335	COG4536	flavin adenine dinucleotide binding
GER12_RS15340	COG4137	Cytochrome C assembly protein
GER12_RS15345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GER12_RS15370	COG2199	diguanylate cyclase activity
GER12_RS15385	COG1605	Chorismate mutase
GER12_RS15385	COG0287	Prephenate dehydrogenase
GER12_RS15395	COG0077	Prephenate dehydratase
GER12_RS15395	COG1605	Chorismate mutase
GER12_RS15405	COG4974	Belongs to the 'phage' integrase family
GER12_RS15445	COG4695	Portal protein
GER12_RS15535	COG5301	cellulose 1,4-beta-cellobiosidase activity
GER12_RS15560	COG1196	nuclear chromosome segregation
GER12_RS15570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GER12_RS15575	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GER12_RS15590	COG0542	response to heat
GER12_RS15620	COG0477	Major facilitator Superfamily
GER12_RS15625	COG5544	Lipoprotein
GER12_RS15630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GER12_RS15645	COG3118	belongs to the thioredoxin family
GER12_RS15650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GER12_RS15670	COG0583	DNA-binding transcription factor activity
GER12_RS15675	COG0513	Belongs to the DEAD box helicase family
GER12_RS15685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GER12_RS15710	COG3086	response to oxidative stress
GER12_RS15750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GER12_RS15755	COG0583	DNA-binding transcription factor activity
GER12_RS15760	COG2223	nitrite transmembrane transporter activity
GER12_RS15765	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GER12_RS15770	COG1737	Transcriptional regulator
GER12_RS15780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GER12_RS15780	COG1263	PTS System
GER12_RS15785	COG0560	Phosphoserine phosphatase
GER12_RS15810	COG2205	protein histidine kinase activity
GER12_RS15815	COG3170	Tfp pilus assembly protein FimV
GER12_RS15820	COG2204	response regulator
GER12_RS15825	COG0347	Belongs to the P(II) protein family
GER12_RS15830	COG3104	oligopeptide transport
GER12_RS15840	COG0531	amino acid
GER12_RS15845	COG3710	Transcriptional regulator
GER12_RS15850	COG1017	nitric oxide dioxygenase activity
GER12_RS15850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GER12_RS15860	COG2814	Major facilitator Superfamily
GER12_RS15865	COG3711	transcriptional antiterminator
GER12_RS15875	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GER12_RS15920	COG0822	iron-sulfur transferase activity
GER12_RS15940	COG0633	Ferredoxin
GER12_RS15945	COG2975	iron-sulfur cluster assembly
GER12_RS15970	COG2897	thiosulfate sulfurtransferase activity
GER12_RS15975	COG2373	Large extracellular alpha-helical protein
GER12_RS15980	COG4953	penicillin-binding protein 1C
GER12_RS15985	COG0243	molybdopterin cofactor binding
GER12_RS15990	COG0437	4 iron, 4 sulfur cluster binding
GER12_RS16030	COG2976	Protein conserved in bacteria
GER12_RS16045	COG1645	bacterial-type flagellum-dependent swarming motility
GER12_RS16080	COG0516	GMP reductase activity
GER12_RS16080	COG0517	IMP dehydrogenase activity
GER12_RS16115	COG2200	EAL domain
GER12_RS16130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GER12_RS16145	COG2233	PERMEase
GER12_RS16155	COG1393	Belongs to the ArsC family
GER12_RS16165	COG0628	permease
GER12_RS16170	COG3835	regulator
GER12_RS16175	COG2610	gluconate transmembrane transporter activity
GER12_RS16180	COG1929	Belongs to the glycerate kinase type-1 family
GER12_RS16185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GER12_RS16190	COG2716	regulation of RNA biosynthetic process
GER12_RS16200	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GER12_RS16210	COG2321	neutral zinc metallopeptidase
GER12_RS16230	COG1393	Belongs to the ArsC family
GER12_RS16240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GER12_RS16245	COG3850	Histidine kinase
GER12_RS16250	COG0493	'glutamate synthase
GER12_RS16250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GER12_RS16255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GER12_RS16265	COG5342	invasion associated locus B
GER12_RS16275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GER12_RS16410	COG2837	iron assimilation
GER12_RS16430	COG4208	sulfate ABC transporter
GER12_RS16435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GER12_RS16485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS16510	COG3530	Putative quorum-sensing-regulated virulence factor
GER12_RS16515	COG0385	Bile acid
GER12_RS16520	COG0583	DNA-binding transcription factor activity
GER12_RS16530	COG2211	Major facilitator Superfamily
GER12_RS16540	COG0583	DNA-binding transcription factor activity
GER12_RS16570	COG3415	Transposase
GER12_RS16575	COG3415	Transposase
GER12_RS16590	COG2200	EAL domain
GER12_RS16590	COG2199	diguanylate cyclase activity
GER12_RS16595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GER12_RS16610	COG0667	Aldo Keto reductase
GER12_RS16615	COG3961	Belongs to the TPP enzyme family
GER12_RS16630	COG0436	Aminotransferase
GER12_RS16640	COG1560	Kdo2-lipid A biosynthetic process
GER12_RS16680	COG2116	formate transmembrane transporter activity
GER12_RS16695	COG3691	Protein conserved in bacteria
GER12_RS16710	COG2062	phosphohistidine phosphatase, SixA
GER12_RS16735	COG0730	response to heat
GER12_RS16740	COG3101	peptidyl-lysine hydroxylation
GER12_RS16755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GER12_RS16775	COG3423	Transcriptional regulator
GER12_RS16800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GER12_RS16810	COG0586	Pfam SNARE associated Golgi protein
GER12_RS16820	COG0285	dihydrofolate synthase activity
GER12_RS16825	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GER12_RS16830	COG1286	toxin biosynthetic process
GER12_RS16835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GER12_RS16840	COG3829	transcription factor binding
GER12_RS16850	COG0531	amino acid
GER12_RS16855	COG3457	Alanine racemase
GER12_RS16860	COG0833	amino acid
GER12_RS16895	COG1090	epimerase
GER12_RS16900	COG0625	glutathione transferase activity
GER12_RS16905	COG0625	glutathione transferase activity
GER12_RS16910	COG0622	Phosphoesterase
GER12_RS16920	COG1609	Transcriptional regulator
GER12_RS16925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS16935	COG3037	sugar-specific permease SgaT UlaA
GER12_RS16940	COG3959	Transketolase, thiamine diphosphate binding domain
GER12_RS16945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GER12_RS16950	COG1288	antiporter activity
GER12_RS16975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GER12_RS16980	COG0471	metal ion transport
GER12_RS16980	COG0490	domain, Protein
GER12_RS16990	COG0436	Aminotransferase
GER12_RS16995	COG0583	DNA-binding transcription factor activity
GER12_RS17045	COG0839	Belongs to the complex I subunit 6 family
GER12_RS17055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GER12_RS17060	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GER12_RS17070	COG0835	chemotaxis
GER12_RS17070	COG0784	Response regulator, receiver
GER12_RS17080	COG2153	protein acetylation
GER12_RS17085	COG4575	ribosome binding
GER12_RS17090	COG1169	isochorismate synthase
GER12_RS17180	COG1414	Transcriptional regulator
GER12_RS17190	COG2271	Major facilitator Superfamily
GER12_RS17210	COG0247	lactate metabolic process
GER12_RS17220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GER12_RS17225	COG2271	Major facilitator Superfamily
GER12_RS17230	COG0584	glycerophosphoryl diester phosphodiesterase
GER12_RS17235	COG0583	DNA-binding transcription factor activity
GER12_RS17240	COG2814	Major facilitator Superfamily
GER12_RS17245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GER12_RS17275	COG4948	Mandelate Racemase Muconate Lactonizing
GER12_RS17295	COG0642	Histidine kinase
GER12_RS17295	COG2198	Histidine kinase
GER12_RS17320	COG4615	Cyclic peptide transporter
GER12_RS17330	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GER12_RS17330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GER12_RS17335	COG3062	negative regulation of establishment of protein localization
GER12_RS17345	COG0437	4 iron, 4 sulfur cluster binding
GER12_RS17350	COG0348	domain, Protein
GER12_RS17355	COG3043	anaerobic respiration
GER12_RS17360	COG3005	denitrification pathway
GER12_RS17365	COG4133	protoheme IX ABC transporter activity
GER12_RS17370	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GER12_RS17375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GER12_RS17380	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GER12_RS17390	COG1138	Cytochrome C-type biogenesis protein
GER12_RS17400	COG3088	subunit of a heme lyase
GER12_RS17400	COG4235	cytochrome complex assembly
GER12_RS17405	COG2197	response regulator
GER12_RS17425	COG5301	cellulose 1,4-beta-cellobiosidase activity
GER12_RS17475	COG1061	Type III restriction enzyme res subunit
GER12_RS17485	COG2814	Major facilitator Superfamily
GER12_RS17495	COG4172	Belongs to the ABC transporter superfamily
GER12_RS17500	COG4239	(ABC) transporter, permease
GER12_RS17505	COG4174	ABC transporter (Permease)
GER12_RS17510	COG4166	transmembrane transport
GER12_RS17515	COG2200	EAL domain
GER12_RS17520	COG0791	NLP P60 protein
GER12_RS17525	COG0671	phosphoesterase, PA-phosphatase related
GER12_RS17530	COG0523	cobalamin synthesis protein
GER12_RS17565	COG1105	Belongs to the carbohydrate kinase PfkB family
GER12_RS17570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GER12_RS17570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GER12_RS17570	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GER12_RS17580	COG2855	membrane
GER12_RS17585	COG0583	DNA-binding transcription factor activity
GER12_RS17590	COG0833	amino acid
GER12_RS17595	COG4771	TonB-dependent receptor
GER12_RS17600	COG2271	Major facilitator Superfamily
GER12_RS17605	COG0560	Phosphoserine phosphatase
GER12_RS17610	COG1760	l-serine dehydratase
GER12_RS17630	COG2311	Membrane
GER12_RS17660	COG0493	'glutamate synthase
GER12_RS17670	COG2949	membrane
GER12_RS17680	COG1346	cytolysis
GER12_RS17695	COG2271	Major facilitator Superfamily
GER12_RS17710	COG0625	glutathione transferase activity
GER12_RS17715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GER12_RS17730	COG1538	Outer membrane efflux protein
GER12_RS17735	COG1028	Short-chain dehydrogenase reductase Sdr
GER12_RS17740	COG0586	Pfam SNARE associated Golgi protein
GER12_RS17750	COG1686	Belongs to the peptidase S11 family
GER12_RS17755	COG0277	FAD linked oxidase domain protein
GER12_RS17765	COG1732	Glycine betaine
GER12_RS17770	COG1174	glycine betaine transport
GER12_RS17775	COG1125	glycine betaine transport
GER12_RS17780	COG1174	glycine betaine transport
GER12_RS17795	COG3275	phosphorelay sensor kinase activity
GER12_RS17805	COG4807	Protein conserved in bacteria
GER12_RS17815	COG4808	Protein conserved in bacteria
GER12_RS17840	COG3121	Chaperone
GER12_RS17845	COG3188	usher protein
GER12_RS17850	COG3539	Fimbrial protein
GER12_RS17855	COG5455	response to cobalt ion
GER12_RS17860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GER12_RS17870	COG2188	Transcriptional regulator
GER12_RS17875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GER12_RS17880	COG1397	ADP-ribosylglycohydrolase
GER12_RS17885	COG2211	Major facilitator Superfamily
GER12_RS17890	COG1830	Aldolase
GER12_RS17935	COG0745	RESPONSE REGULATOR receiver
GER12_RS17940	COG2205	protein histidine kinase activity
GER12_RS17970	COG0443	Heat shock 70 kDa protein
GER12_RS17975	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GER12_RS17980	COG5001	Diguanylate cyclase
GER12_RS17980	COG5002	protein histidine kinase activity
GER12_RS17980	COG3447	MASE1 domain protein
GER12_RS17995	COG2982	Protein involved in outer membrane biogenesis
GER12_RS18000	COG1253	flavin adenine dinucleotide binding
GER12_RS18020	COG0463	Glycosyl transferase, family 2
GER12_RS18025	COG1045	serine acetyltransferase
GER12_RS18030	COG0438	transferase activity, transferring glycosyl groups
GER12_RS18040	COG1216	Glycosyl transferase, family 2
GER12_RS18045	COG0110	maltose O-acetyltransferase activity
GER12_RS18050	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GER12_RS18055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GER12_RS18065	COG0297	glycogen (starch) synthase activity
GER12_RS18080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GER12_RS18085	COG2244	polysaccharide biosynthetic process
GER12_RS18090	COG2327	Polysaccharide pyruvyl transferase
GER12_RS18230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GER12_RS18235	COG0583	DNA-binding transcription factor activity
GER12_RS18245	COG0531	amino acid
GER12_RS18250	COG2925	Exonuclease
GER12_RS18290	COG1289	transmembrane transporter activity
GER12_RS18325	COG4656	Part of a membrane complex involved in electron transport
GER12_RS18360	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GER12_RS18490	COG1122	ATPase activity
GER12_RS18525	COG0640	Transcriptional regulator
GER12_RS18530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GER12_RS18545	COG0798	PFAM Bile acid sodium symporter
GER12_RS18560	COG0534	Mate efflux family protein
GER12_RS18570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GER12_RS18630	COG3423	Transcriptional regulator
GER12_RS18655	COG0582	viral genome integration into host DNA
GER12_RS18710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GER12_RS18720	COG1418	mRNA catabolic process
GER12_RS18725	COG0270	DNA (cytosine-5-)-methyltransferase activity
GER12_RS18730	COG3727	T/G mismatch-specific endonuclease activity
GER12_RS18735	COG0697	spore germination
GER12_RS18740	COG2354	Protein conserved in bacteria
GER12_RS18745	COG5475	Uncharacterized small protein (DUF2158)
GER12_RS18850	COG0425	Belongs to the sulfur carrier protein TusA family
GER12_RS18925	COG2197	response regulator
GER12_RS18940	COG2197	response regulator
GER12_RS18985	COG3012	SEC-C Motif Domain Protein
GER12_RS18985	COG3318	Belongs to the UPF0149 family
GER12_RS18990	COG0814	amino acid
GER12_RS19000	COG1528	Iron-storage protein
GER12_RS19015	COG1528	Iron-storage protein
GER12_RS19120	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GER12_RS19135	COG3102	Protein conserved in bacteria
GER12_RS19155	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GER12_RS19160	COG1801	Protein of unknown function DUF72
GER12_RS19165	COG1335	isochorismatase
GER12_RS19175	COG0494	nUDIX hydrolase
GER12_RS19210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GER12_RS19220	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GER12_RS19225	COG0739	heme binding
GER12_RS19230	COG1560	Kdo2-lipid A biosynthetic process
GER12_RS19240	COG1737	Transcriptional regulator
GER12_RS19245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GER12_RS19250	COG0129	dihydroxy-acid dehydratase activity
GER12_RS19255	COG0800	Aldolase
GER12_RS19265	COG3141	response to X-ray
GER12_RS19275	COG2979	Protein of unknown function (DUF533)
GER12_RS19280	COG1770	oligopeptidase
GER12_RS19285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GER12_RS19290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GER12_RS19300	COG2372	response to copper ion
GER12_RS19305	COG1276	copper resistance
GER12_RS19315	COG0582	viral genome integration into host DNA
GER12_RS19320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GER12_RS19355	COG5301	cellulose 1,4-beta-cellobiosidase activity
GER12_RS19400	COG3328	transposase activity
GER12_RS19410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GER12_RS19415	COG0454	-acetyltransferase
GER12_RS19425	COG5562	phage envelope protein
GER12_RS19460	COG3008	intermembrane lipid transfer
GER12_RS19465	COG2995	paraquat-inducible protein a
GER12_RS19470	COG1956	GAF domain-containing protein
GER12_RS19490	COG2814	Major facilitator Superfamily
GER12_RS19495	COG1414	Transcriptional regulator
GER12_RS19525	COG0768	penicillin binding
GER12_RS19530	COG2226	methyltransferase
GER12_RS19545	COG3716	PTS system mannose fructose sorbose family IID component
GER12_RS19550	COG3715	PTS system
GER12_RS19555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GER12_RS19555	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS19560	COG1253	flavin adenine dinucleotide binding
GER12_RS19565	COG2200	EAL domain
GER12_RS19570	COG1760	l-serine dehydratase
GER12_RS19590	COG0251	oxidation-reduction process
GER12_RS19595	COG1199	ATP-dependent helicase activity
GER12_RS19605	COG3065	identical protein binding
GER12_RS19615	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GER12_RS19625	COG2894	cell division
GER12_RS19640	COG0179	Fumarylacetoacetate (FAA) hydrolase
GER12_RS19680	COG2719	SpoVR family
GER12_RS19700	COG1619	proteins homologs of microcin C7 resistance protein MccF
GER12_RS19725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GER12_RS19735	COG1294	oxidase, subunit
GER12_RS19740	COG1271	oxidase subunit
GER12_RS19745	COG1773	rubredoxin
GER12_RS19750	COG1999	signal sequence binding
GER12_RS19755	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GER12_RS19760	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
GER12_RS19770	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GER12_RS19790	COG0012	GTP binding
GER12_RS19805	COG0659	secondary active sulfate transmembrane transporter activity
GER12_RS19855	COG0387	Pfam Sodium calcium exchanger
GER12_RS19860	COG4572	Cation transport regulator
GER12_RS19865	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GER12_RS19870	COG4932	domain protein
GER12_RS19875	COG2197	response regulator
GER12_RS19880	COG3850	Histidine kinase
GER12_RS19885	COG2223	nitrite transmembrane transporter activity
GER12_RS19890	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GER12_RS19895	COG1140	nitrate reductase beta subunit
GER12_RS19900	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GER12_RS19905	COG2181	nitrate reductase activity
GER12_RS19935	COG0788	formyltetrahydrofolate deformylase activity
GER12_RS19945	COG1752	Esterase of the alpha-beta hydrolase superfamily
GER12_RS19950	COG0745	RESPONSE REGULATOR receiver
GER12_RS19955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GER12_RS19970	COG1012	belongs to the aldehyde dehydrogenase family
GER12_RS19970	COG1454	alcohol dehydrogenase
GER12_RS19975	COG2095	MarC family integral membrane protein
GER12_RS20005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GER12_RS20025	COG2350	Protein conserved in bacteria
GER12_RS20050	COG0727	PFAM Uncharacterised protein family (UPF0153)
GER12_RS20060	COG3546	catalase activity
GER12_RS20065	COG3685	Protein conserved in bacteria
GER12_RS20070	COG3685	Protein conserved in bacteria
GER12_RS20075	COG3729	General stress protein
GER12_RS20115	COG0009	L-threonylcarbamoyladenylate synthase
GER12_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
GER12_RS20135	COG0616	signal peptide processing
GER12_RS20175	COG0671	phosphoesterase, PA-phosphatase related
GER12_RS20180	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GER12_RS20185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GER12_RS20205	COG1349	DNA-binding transcription factor activity
GER12_RS20215	COG5001	Diguanylate cyclase
GER12_RS20225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GER12_RS20225	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GER12_RS20280	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GER12_RS20285	COG1842	Phage shock protein A
GER12_RS20295	COG1983	PspC domain protein
GER12_RS20305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GER12_RS20310	COG3106	COG3106 Predicted ATPase
GER12_RS20330	COG4948	Mandelate Racemase Muconate Lactonizing
GER12_RS20335	COG2866	Carboxypeptidase
GER12_RS20340	COG4166	transmembrane transport
GER12_RS20350	COG0583	DNA-binding transcription factor activity
GER12_RS20355	COG0656	L-ascorbic acid biosynthetic process
GER12_RS20360	COG1028	Short-chain dehydrogenase reductase Sdr
GER12_RS20365	COG1309	transcriptional regulator
GER12_RS20400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GER12_RS20420	COG0668	transmembrane transport
GER12_RS20425	COG3182	Iron-regulated membrane protein
GER12_RS20445	COG2840	Smr protein MutS2
GER12_RS20450	COG0840	transmembrane signaling receptor activity
GER12_RS20460	COG0513	Belongs to the DEAD box helicase family
GER12_RS20475	COG2076	Multidrug Resistance protein
GER12_RS20485	COG0674	pyruvate-flavodoxin oxidoreductase activity
GER12_RS20485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GER12_RS20485	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GER12_RS20485	COG1013	pyruvate-flavodoxin oxidoreductase activity
GER12_RS20495	COG3042	response to heat
GER12_RS20500	COG3187	Heat shock protein
GER12_RS20505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GER12_RS20510	COG2911	Protein conserved in bacteria
GER12_RS20520	COG3784	Protein of unknown function (DUF1318)
GER12_RS20535	COG1643	Atp-dependent helicase
GER12_RS20540	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GER12_RS20545	COG3038	cytochrome b561
GER12_RS20550	COG0500	methyltransferase
GER12_RS20560	COG0765	amino acid transport
GER12_RS20570	COG0765	amino acid transport
GER12_RS20575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GER12_RS20610	COG0840	transmembrane signaling receptor activity
GER12_RS20615	COG0583	DNA-binding transcription factor activity
GER12_RS20620	COG5383	Protein conserved in bacteria
GER12_RS20625	COG2272	Belongs to the type-B carboxylesterase lipase family
GER12_RS20630	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GER12_RS20635	COG2353	YceI-like domain
GER12_RS20640	COG1304	FMN binding
GER12_RS20650	COG1349	DNA-binding transcription factor activity
GER12_RS20655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GER12_RS20660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GER12_RS20665	COG0434	BtpA family
GER12_RS20670	COG3775	system Galactitol-specific IIC component
GER12_RS20675	COG3414	Phosphotransferase system galactitol-specific IIB component
GER12_RS20685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GER12_RS20690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GER12_RS20695	COG1275	C4-dicarboxylate transporter malic acid transport protein
GER12_RS20700	COG0500	methyltransferase
GER12_RS20710	COG3135	benzoate transporter
GER12_RS20715	COG1396	sequence-specific DNA binding
GER12_RS20720	COG0826	peptidase U32
GER12_RS20745	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GER12_RS20750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GER12_RS20790	COG3238	Protein conserved in bacteria
GER12_RS20800	COG2130	NADP-dependent
GER12_RS20805	COG1802	Transcriptional regulator
GER12_RS20810	COG4772	TonB-dependent receptor
GER12_RS20815	COG3391	amine dehydrogenase activity
GER12_RS20845	COG2181	nitrate reductase activity
GER12_RS20850	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GER12_RS20855	COG1140	nitrate reductase beta subunit
GER12_RS20860	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GER12_RS20900	COG0437	4 iron, 4 sulfur cluster binding
GER12_RS20905	COG2864	formate dehydrogenase
GER12_RS20910	COG1064	alcohol dehydrogenase
GER12_RS20930	COG1764	response to oxidative stress
GER12_RS20945	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GER12_RS20960	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GER12_RS20965	COG1757	Na H antiporter
GER12_RS20970	COG1609	Transcriptional regulator
GER12_RS21020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GER12_RS21045	COG2271	Major facilitator Superfamily
GER12_RS21050	COG1063	alcohol dehydrogenase
GER12_RS21055	COG2186	Transcriptional regulator
GER12_RS21065	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GER12_RS21070	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GER12_RS21095	COG1773	rubredoxin
GER12_RS21120	COG3781	membrane
GER12_RS21135	COG1012	belongs to the aldehyde dehydrogenase family
GER12_RS21140	COG0583	DNA-binding transcription factor activity
GER12_RS21175	COG2814	Major facilitator Superfamily
GER12_RS21185	COG3111	PFAM Bacterial OB fold (BOF) protein
GER12_RS21190	COG1546	Belongs to the CinA family
GER12_RS21195	COG3729	General stress protein
GER12_RS21205	COG4221	oxidoreductase activity
GER12_RS21210	COG1802	Transcriptional regulator
GER12_RS21220	COG0246	Mannitol dehydrogenase
GER12_RS21225	COG0477	Major facilitator Superfamily
GER12_RS21230	COG1063	alcohol dehydrogenase
GER12_RS21250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GER12_RS21265	COG0243	molybdopterin cofactor binding
GER12_RS21270	COG0243	molybdopterin cofactor binding
GER12_RS21275	COG0437	4 iron, 4 sulfur cluster binding
GER12_RS21280	COG3302	dmso reductase anchor subunit
GER12_RS21320	COG1940	carbohydrate kinase activity
GER12_RS21325	COG0583	DNA-binding transcription factor activity
GER12_RS21330	COG2814	Major facilitator Superfamily
GER12_RS21340	COG3591	Belongs to the peptidase S1B family
GER12_RS21355	COG0628	permease
GER12_RS21360	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GER12_RS21365	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GER12_RS21375	COG0531	amino acid
GER12_RS21380	COG3136	membrane protein required for alginate biosynthesis
GER12_RS21385	COG0745	RESPONSE REGULATOR receiver
GER12_RS21395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GER12_RS21400	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GER12_RS21405	COG2205	protein histidine kinase activity
GER12_RS21430	COG5339	Protein conserved in bacteria
GER12_RS21440	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GER12_RS21450	COG0673	inositol 2-dehydrogenase activity
GER12_RS21500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GER12_RS21510	COG0625	glutathione transferase activity
GER12_RS21530	COG3895	Periplasmic Protein
GER12_RS21555	COG1566	PFAM secretion protein HlyD family protein
GER12_RS21570	COG4989	oxidoreductase activity
GER12_RS21575	COG3313	Fe-S protein
GER12_RS21580	COG1309	transcriptional regulator
GER12_RS21585	COG1902	pentaerythritol trinitrate reductase activity
GER12_RS21600	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GER12_RS21605	COG0791	NLP P60 protein
GER12_RS21625	COG0583	DNA-binding transcription factor activity
GER12_RS21630	COG2814	Major facilitator Superfamily
GER12_RS21635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GER12_RS21640	COG0307	riboflavin synthase, alpha
GER12_RS21820	COG0789	Transcriptional regulator
GER12_RS21825	COG3272	Protein of unknown function (DUF1722)
GER12_RS21860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GER12_RS21870	COG2267	carboxylic ester hydrolase activity
GER12_RS21875	COG0531	amino acid
GER12_RS21900	COG1376	ErfK ybiS ycfS ynhG family protein
GER12_RS21915	COG0719	Fe-S assembly protein
GER12_RS21920	COG0396	ATPase activity
GER12_RS21925	COG0719	Fe-S assembly protein
GER12_RS21930	COG0316	Belongs to the HesB IscA family
GER12_RS21945	COG2050	protein possibly involved in aromatic compounds catabolism
GER12_RS21950	COG0247	lactate metabolic process
GER12_RS21950	COG0277	FAD linked oxidase domain protein
GER12_RS21955	COG0628	permease
GER12_RS21970	COG0738	Major facilitator superfamily
GER12_RS21975	COG2271	Major facilitator Superfamily
GER12_RS21990	COG4670	ketone body catabolic process
GER12_RS21995	COG1960	acyl-CoA dehydrogenase activity
GER12_RS22000	COG2207	Transcriptional regulator
GER12_RS22000	COG1917	Cupin 2, conserved barrel domain protein
GER12_RS22005	COG2086	electron transfer activity
GER12_RS22010	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GER12_RS22015	COG0644	oxidoreductase
GER12_RS22020	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GER12_RS22025	COG0318	PFAM AMP-dependent synthetase and ligase
GER12_RS22030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GER12_RS22030	COG0574	Belongs to the PEP-utilizing enzyme family
GER12_RS22045	COG4256	Hemin uptake protein
GER12_RS22060	COG0791	NLP P60 protein
GER12_RS22070	COG0386	Belongs to the glutathione peroxidase family
GER12_RS22135	COG3137	Salt-induced outer membrane protein
GER12_RS22140	COG1105	Belongs to the carbohydrate kinase PfkB family
GER12_RS22150	COG3001	Fructosamine kinase
GER12_RS22160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GER12_RS22165	COG1988	membrane-bound metal-dependent
GER12_RS22180	COG0753	catalase activity
GER12_RS22190	COG1486	melibiose metabolic process
GER12_RS22195	COG2169	Transcriptional regulator
GER12_RS22195	COG1917	Cupin 2, conserved barrel domain protein
GER12_RS22200	COG1447	Phosphotransferase system cellobiose-specific component IIA
GER12_RS22205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GER12_RS22210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GER12_RS22215	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GER12_RS22230	COG3678	ATP-independent chaperone mediated protein folding
GER12_RS22265	COG0494	nUDIX hydrolase
GER12_RS22280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GER12_RS22290	COG0778	Nitroreductase
GER12_RS22295	COG0616	signal peptide processing
GER12_RS22300	COG0252	asparaginase activity
GER12_RS22305	COG1335	isochorismatase
GER12_RS22310	COG3139	Protein of unknown function (DUF1315)
GER12_RS22330	COG0656	L-ascorbic acid biosynthetic process
GER12_RS22335	COG0641	radical SAM
GER12_RS22340	COG3713	MltA-interacting MipA family protein
GER12_RS22420	COG4974	Belongs to the 'phage' integrase family
GER12_RS22530	COG1192	Involved in chromosome partitioning
GER12_RS22725	COG4372	Transposase
GER12_RS22730	COG3436	PFAM IS66 Orf2 family protein
GER12_RS23055	COG2805	Type II/IV secretion system protein
GER12_RS23105	COG0741	lytic transglycosylase activity
GER12_RS23120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GER12_RS23210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GER12_RS23270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GER12_RS23335	COG1983	PspC domain protein
GER12_RS23345	COG1842	Phage shock protein A
GER12_RS23350	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GER12_RS23405	COG0789	Transcriptional regulator
GER12_RS23525	COG0616	signal peptide processing