locus-tag class description GE198_RS00005 ENOG4105CYN Serine protein kinase GE198_RS00020 ENOG4108KHP Diguanylate cyclase GE198_RS00025 ENOG4108KXH Ybak prolyl-tRNA synthetase associated GE198_RS00040 ENOG4105R1U AraC Family Transcriptional Regulator GE198_RS00045 ENOG4105DJ2 Major Facilitator Superfamily GE198_RS00050 ENOG4105K78 MarR family Transcriptional regulator GE198_RS00060 ENOG4105UCG Domain of unknown function (DUF333) GE198_RS00065 ENOG4106G4W GE198_RS00070 ENOG4105Y3U Transglycosylase-associated protein GE198_RS00080 ENOG4105YP6 Domain of unknown function (DUF1869) GE198_RS00085 ENOG4108YS1 cytoplasmic protein GE198_RS00095 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) GE198_RS00110 ENOG4108Z6Z Transcriptional regulator GE198_RS00125 ENOG4108MEK Metal-binding protein YodA GE198_RS00140 ENOG4105D64 Mechanosensitive ion channel GE198_RS00145 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) GE198_RS00150 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) GE198_RS00165 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein GE198_RS00175 ENOG4108VKM cytochrome b561 GE198_RS00185 ENOG4108ZNX Heat shock protein GE198_RS00210 ENOG4105H38 Membrane GE198_RS00220 ENOG41060EU Cold shock-like protein GE198_RS00225 ENOG4106F2Y RICIN GE198_RS00230 ENOG4105Y50 Virulence Protein GE198_RS00245 ENOG4108HMX isocitrate dehydrogenase (NADP) GE198_RS00250 ENOG4108R99 pseudouridine synthase GE198_RS00275 ENOG4107QTF adenylosuccinate lyase GE198_RS00290 ENOG4105EZE Cupin 4 family protein GE198_RS00305 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GE198_RS00320 ENOG4105D38 putrescine abc transporter GE198_RS00325 ENOG4108HM4 ABC transporter GE198_RS00330 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) GE198_RS00340 ENOG4105D60 lipoprotein releasing system transmembrane protein GE198_RS00345 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) GE198_RS00350 ENOG4105D60 lipoprotein releasing system transmembrane protein GE198_RS00355 ENOG4108JA2 transcriptioN-repair coupling factor GE198_RS00360 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GE198_RS00365 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction GE198_RS00370 ENOG4108IND Tetr family transcriptional regulator GE198_RS00375 ENOG4107MBR 17 kDa surface antigen GE198_RS00380 ENOG4105CEP NADH dehydrogenase GE198_RS00400 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) GE198_RS00405 ENOG41090DQ Lipoprotein GE198_RS00410 ENOG4105K59 histidine triad (HIT) protein GE198_RS00415 ENOG4105CNM Receptor GE198_RS00420 ENOG4105CI1 PTS System GE198_RS00425 ENOG4105F8V Hydrolase, tatD family GE198_RS00430 ENOG4107QRG dna polymerase iii GE198_RS00440 ENOG4105HHA aminodeoxychorismate lyase GE198_RS00445 ENOG4105YAZ 4-amino-4-deoxychorismate lyase GE198_RS00450 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GE198_RS00455 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GE198_RS00460 ENOG4105CHR reductase GE198_RS00465 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase GE198_RS00485 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein GE198_RS00490 ENOG4108UHJ MAF-like protein GE198_RS00505 ENOG4105EI2 Pseudouridine synthase GE198_RS00510 ENOG4107QQB Ribonuclease E GE198_RS00515 ENOG4105DTJ flagellar hook-associated protein GE198_RS00520 ENOG4105E1Q flagellar hook-associated protein GE198_RS00525 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj GE198_RS00540 ENOG4105CGA flagellar basal-body rod protein FlgG GE198_RS00545 ENOG4108KPB Flagellar basal-body rod protein FlgF GE198_RS00550 ENOG4105BZE flagellar hook protein, FlgE GE198_RS00555 ENOG4105W00 Flagellar hook capping protein GE198_RS00560 ENOG4108ZC9 flagellar basal-body rod protein flgc GE198_RS00565 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) GE198_RS00570 ENOG4105CKS Flagella basal body P-ring formation protein flgA GE198_RS00575 ENOG4105M9M anti-sigma28 factor FlgM GE198_RS00580 ENOG4105QVD Flagella synthesis protein FlgN GE198_RS00585 ENOG4105CJR Integral membrane protein (MviN GE198_RS00590 ENOG4105EP9 oxidoreductase GE198_RS00600 ENOG4105D9U N-acetyltransferase GE198_RS00610 ENOG4105E9S glutaredoxin 2 GE198_RS00615 ENOG4105F3T (LipO)protein GE198_RS00625 ENOG4105MEA DNA damage-inducible protein i GE198_RS00630 ENOG4105PVA Biofilm formation regulatory protein BssS GE198_RS00640 ENOG4106974 biofilm formation GE198_RS00645 ENOG4105DS1 cytochrome b561 GE198_RS00650 ENOG4108YYC ycei family GE198_RS00660 ENOG4105D1S lipid A biosynthesis GE198_RS00670 ENOG4108W47 Acidic protein msyB GE198_RS00675 ENOG4105NAC (LipO)protein GE198_RS00680 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) GE198_RS00695 ENOG4107RZC phospholipase d GE198_RS00705 ENOG41068SS GE198_RS00710 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) GE198_RS00715 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin GE198_RS00720 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers GE198_RS00725 ENOG41086KC Transcriptional regulator GE198_RS00730 ENOG4108XDW curli assembly protein CsgE GE198_RS00735 ENOG4108WYR Curli production assembly transport component, CsgF GE198_RS00740 ENOG4105P8Q Curli production assembly transport component CsgG GE198_RS00745 ENOG4108UQ5 membrane protein YcdZ GE198_RS00750 ENOG4107XHZ cytoplasmic chaperone TorD family protein GE198_RS00770 ENOG4107RJ5 oxidoreductase GE198_RS00775 ENOG4105JHE Major Facilitator Superfamily GE198_RS00780 ENOG4108QGT oligogalacturonate-specific porin GE198_RS00790 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) GE198_RS00795 ENOG4107RJ1 sodium solute GE198_RS00800 ENOG4105QEK Transcriptional regulator GE198_RS00805 ENOG4105D5M phosphate starvation-inducible protein GE198_RS00810 ENOG4105CK7 Sodium proline symporter GE198_RS00825 ENOG4108R86 Transcriptional regulator GE198_RS00830 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 GE198_RS00835 ENOG4105CS1 NAD(P)H quinone oxidoreductase GE198_RS00840 ENOG4105XH3 GE198_RS00845 ENOG4105D6F Phosphatase GE198_RS00850 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GE198_RS00855 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) GE198_RS00860 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) GE198_RS00915 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase GE198_RS00920 ENOG4105C26 Dehydrogenase GE198_RS00930 ENOG4108V8F Transcriptional regulator, MarR family GE198_RS00935 ENOG4105EFA 4-hydroxyphenylacetate GE198_RS00940 ENOG4107UWN reductase GE198_RS00950 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GE198_RS00955 ENOG4107ZY3 Histidine kinase GE198_RS00970 ENOG4106YSC GE198_RS00975 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell GE198_RS00990 ENOG41084BJ Pentapeptide repeat protein GE198_RS01005 ENOG4108MN8 Membrane GE198_RS01015 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 GE198_RS01025 ENOG4108V1U phospholipid-binding protein GE198_RS01040 ENOG4105K4P CoA-binding domain protein GE198_RS01050 ENOG4108Z5K methylglyoxal synthase GE198_RS01055 ENOG41088T4 Helicase IV GE198_RS01060 ENOG410901E Membrane GE198_RS01065 ENOG4105EM2 membrane GE198_RS01070 ENOG4108RZ1 DNA transformation protein GE198_RS01080 ENOG4105UYK outer membrane protein a GE198_RS01090 ENOG4105DAN ATP-dependent protease GE198_RS01100 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) GE198_RS01105 ENOG4108Q2G (LipO)protein GE198_RS01110 ENOG4105DY2 Paraquat-inducible protein b GE198_RS01115 ENOG4105F1S paraquat-inducible protein a GE198_RS01120 ENOG4105C5H ABC transporter GE198_RS01130 ENOG4105QVC MOSC domain-containing protein GE198_RS01135 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) GE198_RS01145 ENOG4105CD8 aminopeptidase N GE198_RS01160 ENOG4107RCH Diaminopropionate ammonia-lyase GE198_RS01170 ENOG4105C5S asparaginyl-tRNA synthetase GE198_RS01180 ENOG4105FCK Membrane GE198_RS01185 ENOG4105CGF Aromatic amino acid aminotransferase GE198_RS01190 ENOG4105C5X domain protein GE198_RS01195 ENOG4105EAQ (twin-arginine translocation) pathway signal GE198_RS01200 ENOG4105DIT ErfK YbiS YcfS YnhG family protein GE198_RS01210 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) GE198_RS01220 ENOG4106371 Methyltransferase GE198_RS01225 ENOG4107S90 membrAne GE198_RS01230 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups GE198_RS01245 ENOG4105T0Z Conserved Protein GE198_RS01255 ENOG4105BZ1 (ABC) transporter GE198_RS01260 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 GE198_RS01265 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) GE198_RS01270 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) GE198_RS01280 ENOG4108K0D peptidase, M48 GE198_RS01295 ENOG4107VMU Membrane GE198_RS01300 ENOG4105DDY UPF0142 protein ycaO GE198_RS01305 ENOG4105TMB Formate nitrite transporter GE198_RS01310 ENOG4105C6N Formate acetyltransferase GE198_RS01315 ENOG4105GUS GE198_RS01325 ENOG4105F1A Pyruvate formate-lyase GE198_RS01330 ENOG4105E5D amino acid GE198_RS01340 ENOG4107KGK dmso reductase anchor subunit GE198_RS01345 ENOG4105QAX Iron-sulfur GE198_RS01350 ENOG4107QY8 reductase GE198_RS01360 ENOG4105D1H recombination factor protein RarA GE198_RS01370 ENOG4105CNU cell division protein FtsK GE198_RS01375 ENOG4105EW9 transcriptional regulator AsnC family GE198_RS01380 ENOG4105C3M thioredoxin reductase GE198_RS01385 ENOG4108JJ9 ABC, transporter GE198_RS01390 ENOG4108JJ8 (ABC) transporter GE198_RS01405 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) GE198_RS01410 ENOG4105HEI LysR family (Transcriptional regulator GE198_RS01415 ENOG4105EUB pirin domain protein GE198_RS01420 ENOG4105CHJ isochorismatase hydrolase GE198_RS01505 ENOG4108YX2 DNA-binding protein GE198_RS01540 ENOG4105DFP Integrase GE198_RS01555 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GE198_RS01565 ENOG4105VEQ Cold shock protein GE198_RS01570 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) GE198_RS01575 ENOG4105DJY efflux transporter, rnd family, mfp subunit GE198_RS01580 ENOG4108MJ5 VirK protein GE198_RS01585 ENOG4105CPB ATP-dependent endonuclease of the OLD family GE198_RS01590 ENOG4105DWU Membrane GE198_RS01600 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GE198_RS01605 ENOG4105C7K acetolactate synthase GE198_RS01610 ENOG4105C5W Aldolase GE198_RS01615 ENOG4105CGD Nad-dependent epimerase dehydratase GE198_RS01620 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase GE198_RS01625 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase GE198_RS01635 ENOG41064MM (LipO)protein GE198_RS01640 ENOG4105E5Z arginine transporter ATP-binding subunit GE198_RS01645 ENOG4106PMH Extracellular solute-binding protein family 3 GE198_RS01650 ENOG4105GBT ABC transporter GE198_RS01655 ENOG4105DMR ABC, transporter GE198_RS01660 ENOG4106TNF Periplasmic binding protein GE198_RS01685 ENOG4105RBQ inner membrane protein ybjO GE198_RS01690 ENOG4105D38 putrescine abc transporter GE198_RS01695 ENOG4105F38 ABC transporter, permease GE198_RS01700 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GE198_RS01705 ENOG4107RUE extracellular solute-binding protein family 1 GE198_RS01710 ENOG4108RMJ sensory transduction regulator GE198_RS01720 ENOG4108DBC nitroreductase GE198_RS01725 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress GE198_RS01730 ENOG41090BQ Glutaredoxin GE198_RS01735 ENOG4105GWF inner membrane protein YbjM GE198_RS01745 ENOG4108RFG Tetr family transcriptional regulator GE198_RS01750 ENOG4106UW1 Major Facilitator superfamily GE198_RS01755 ENOG4108HCJ Hydrolase GE198_RS01760 ENOG4107QF7 multi-drug GE198_RS01765 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase GE198_RS01770 ENOG4107FB0 transcriptional regulator DeoR family GE198_RS01775 ENOG4105DZ1 carboxypeptidase GE198_RS01780 ENOG4108TGY Glutathione S-transferase GE198_RS01785 ENOG4105D8V Glucose sorbosone dehydrogenase GE198_RS01790 ENOG4105CY2 Citrate transporter GE198_RS01795 ENOG4108KB2 LysR family Transcriptional regulator GE198_RS01800 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GE198_RS01805 ENOG4105C1G acyl-Coa dehydrogenase GE198_RS01815 ENOG4105C10 Electron transfer flavoprotein GE198_RS01820 ENOG4105BZJ Electron transfer flavoprotein GE198_RS01825 ENOG4105CI0 Citrate lyase GE198_RS01830 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway GE198_RS01850 ENOG4105DEF Extracellular solute-binding protein, family 5 GE198_RS01855 ENOG4108JQ6 ABC transporter GE198_RS01860 ENOG4105D44 asparaginase GE198_RS01865 ENOG4105CVM Molybdenum cofactor synthesis domain protein GE198_RS01870 ENOG4105D06 uba thif-type nad fad binding protein GE198_RS01875 ENOG4105F1A Pyruvate formate-lyase GE198_RS01885 ENOG4108HCJ Hydrolase GE198_RS01890 ENOG41072TH Protein of unknown function (DUF1479) GE198_RS01905 ENOG4105C5H ABC transporter GE198_RS01910 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GE198_RS01915 ENOG4105F4P )-transporter GE198_RS01920 ENOG4105KST dependent repressor GE198_RS01930 ENOG4108I6E Sulfatase GE198_RS01935 ENOG4108T1M outer membrane protein x GE198_RS01950 ENOG4107R0W ABC transporter GE198_RS01955 ENOG4105E5Q amino acid AbC transporter GE198_RS01960 ENOG4105CDA abc transporter atp-binding protein GE198_RS01965 ENOG4105D8X mechanosensitive ion channel GE198_RS01975 ENOG4105KSC Transcriptional regulator, TraR DksA family GE198_RS01980 ENOG4105VR4 UPF0379 protein ybiJ GE198_RS01985 ENOG4108MTB glycosyl transferase family GE198_RS01990 ENOG4105DVT helicase GE198_RS01995 ENOG4105C1J atp-dependent rna helicase GE198_RS02000 ENOG4107MVR Transcriptional regulator GE198_RS02010 ENOG4105CJ1 ABC, transporter GE198_RS02015 ENOG4107QWP ABC-2 type transporter GE198_RS02020 ENOG4107QWP ABC-2 type transporter GE198_RS02025 ENOG4105I9U inner membrane protein ybhQ GE198_RS02030 ENOG4105X23 Endonuclease Exonuclease phosphatase GE198_RS02035 ENOG4105DZQ phospholipase D Transphosphatidylase GE198_RS02040 ENOG4107UXM Membrane GE198_RS02060 ENOG4105HFZ Membrane GE198_RS02065 ENOG4108ZAF Molybdopterin GE198_RS02070 ENOG4105M00 molybdopterin converting factor, subunit 1 GE198_RS02080 ENOG4108RIR Molybdenum cofactor biosynthesis protein GE198_RS02090 ENOG4105CHW UPF0052 protein GE198_RS02105 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) GE198_RS02110 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GE198_RS02125 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) GE198_RS02130 ENOG4108V1U phospholipid-binding protein GE198_RS02160 ENOG4105NBR Pectinesterase GE198_RS02170 ENOG4108K4B hydrolase GE198_RS02180 ENOG4105E0C molybdate abc transporter GE198_RS02185 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein GE198_RS02195 ENOG4105F4R Transcriptional regulator mode GE198_RS02200 ENOG4105DKW ABC transporter GE198_RS02210 ENOG4105CMR udp-glucose 4-epimerase GE198_RS02215 ENOG4105F0Z galactose-1-phosphate uridylyltransferase GE198_RS02225 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) GE198_RS02235 ENOG4105E0A ABC, transporter GE198_RS02240 ENOG4105EHG Permease protein GE198_RS02245 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase GE198_RS02250 ENOG4105D9Q decarboxylase (Beta subunit) GE198_RS02255 ENOG4107QSA Oxaloacetate decarboxylase GE198_RS02265 ENOG4107QWE )-transporter GE198_RS02275 ENOG4105C5Q Transcriptional regulator GE198_RS02285 ENOG4107GFK fumarate GE198_RS02290 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GE198_RS02295 ENOG4105JND homeobox protein GE198_RS02300 ENOG4105PGM cation diffusion facilitator family transporter GE198_RS02305 ENOG4106Z1T Nicotinamide Mononucleotide Transporter GE198_RS02340 ENOG4105UFD tol-pal system protein YbgF GE198_RS02345 ENOG4105KCK Peptidoglycan-associated lipoprotein GE198_RS02355 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA GE198_RS02365 ENOG4105E02 MotA TolQ exbB proton channel GE198_RS02370 ENOG4107YD3 Thioesterase GE198_RS02375 ENOG4105KJB cyd operon protein YbgE GE198_RS02385 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GE198_RS02390 ENOG4105C4M (Ubiquinol oxidase) subunit I GE198_RS02395 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha GE198_RS02405 ENOG4105C7S Dehydrogenase GE198_RS02410 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 GE198_RS02415 ENOG4105E33 succinate dehydrogenase GE198_RS02420 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) GE198_RS02425 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein GE198_RS02430 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit GE198_RS02440 ENOG4105BZN citrate synthase GE198_RS02445 ENOG4108KK1 membrane protein AbrB duplication GE198_RS02470 ENOG410602S Transferase GE198_RS02510 ENOG4108W9T type 1 fimbriae regulatory protein GE198_RS02525 ENOG4107R7A Allophanate hydrolase subunit 2 GE198_RS02530 ENOG4105P4J Allophanate hydrolase, subunit 1 GE198_RS02535 ENOG4107QNR UPF0135 protein GE198_RS02545 ENOG4105CVP deoxyribo-dipyrimidine photolyase GE198_RS02550 ENOG4105XIQ Protein of unknown function (DUF2517) GE198_RS02575 ENOG4105C08 Histidine kinase GE198_RS02580 ENOG4105EEX Two component transcriptional regulator (Winged helix family GE198_RS02590 ENOG4105CXN decarboxylase GE198_RS02595 ENOG4105D5Q Arginine ornithine antiporter GE198_RS02605 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 GE198_RS02610 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) GE198_RS02615 ENOG4105EV9 Alpha Beta Hydrolase GE198_RS02620 ENOG4105NNH LexA regulated protein GE198_RS02625 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) GE198_RS02630 ENOG41090R7 Ferric uptake GE198_RS02635 ENOG4106P55 Transcriptional regulator GE198_RS02640 ENOG4107EFR Flavocytochrome c GE198_RS02645 ENOG41079YP Citrate utilization protein b GE198_RS02650 ENOG4105CSH Transporter GE198_RS02655 ENOG4105GX6 (LipO)protein GE198_RS02660 ENOG4105J5J Outer membrane porin GE198_RS02670 ENOG4105CI1 PTS System GE198_RS02680 ENOG4105CE4 GlcNAc 6-P deacetylase GE198_RS02685 ENOG4105E2R ROK family GE198_RS02690 ENOG4105D4U had-superfamily hydrolase, subfamily iia GE198_RS02695 ENOG4105CAQ asparagine synthetase GE198_RS02735 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family GE198_RS02745 ENOG4105C9A Phoh family GE198_RS02755 ENOG4108JU5 Magnesium and cobalt efflux protein GE198_RS02760 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) GE198_RS02765 ENOG4107RP9 extracellular solute-binding protein, family 3 GE198_RS02770 ENOG4105EAD ABC transporter GE198_RS02775 ENOG4105DRP amino acid AbC transporter GE198_RS02780 ENOG4105CDA abc transporter atp-binding protein GE198_RS02795 ENOG4105F7F Chaperone GE198_RS02800 ENOG4105QFC Hsc56 co-chaperone of HscC GE198_RS02805 ENOG41069CF Protein of unknown function (DUF1266) GE198_RS02810 ENOG4105QFC Hsc56 co-chaperone of HscC GE198_RS02815 ENOG41069CF Protein of unknown function (DUF1266) GE198_RS02825 ENOG4107PAI alpha helical protein GE198_RS02830 ENOG4108JUB Transcriptional regulator GE198_RS02835 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) GE198_RS02860 ENOG4105DJF DNA polymerase III, delta' subunit GE198_RS02865 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) GE198_RS02870 ENOG4107QZB decarboxylase GE198_RS02875 ENOG4108TGR phosphatase GE198_RS02880 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) GE198_RS02885 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) GE198_RS02890 ENOG4105CJN penicillin-binding protein GE198_RS02895 ENOG4105CNI cell division protein FtsW GE198_RS02900 ENOG4105K6T rare lipoprotein A GE198_RS02905 ENOG4105DZ1 carboxypeptidase GE198_RS02910 ENOG4108Z43 UPF0250 protein GE198_RS02920 ENOG41064T2 transcriptional regulator, lysR family GE198_RS02940 ENOG4107Z6W Protein CrcB homolog GE198_RS02955 ENOG4105CEE C4-dicarboxylate transporter GE198_RS02960 ENOG4106YYS transcriptional regulatory protein GE198_RS02965 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism GE198_RS02970 ENOG4105DUA (citrate (pro-3S)-lyase ligase GE198_RS02975 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) GE198_RS02980 ENOG4105CI0 Citrate lyase GE198_RS02985 ENOG4105CHY citrate lyase, alpha GE198_RS02990 ENOG4105YGP holo-ACP synthase CitX GE198_RS03000 ENOG4107QPK )-transporter GE198_RS03005 ENOG4105KTS ribonuclease GE198_RS03010 ENOG4105NXH GreA GreB family elongation factor GE198_RS03015 ENOG4105E2A Dehydrogenase GE198_RS03020 ENOG4108U51 Universal stress protein GE198_RS03030 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GE198_RS03035 ENOG4107QY8 reductase GE198_RS03045 ENOG4108JU3 Alkyl hydroperoxide reductase GE198_RS03050 ENOG4105D3R alkyl hydroperoxide reductase GE198_RS03055 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase GE198_RS03060 ENOG4105DQS Transcriptional regulator GE198_RS03065 ENOG4105BZV Phosphoadenosine phosphosulfate reductase GE198_RS03070 ENOG4105GTN ParB Domain Protein Nuclease GE198_RS03075 ENOG4105CHM Aminotransferase GE198_RS03080 ENOG4107SCQ Iron-containing alcohol dehydrogenase GE198_RS03085 ENOG4105VCD cytoplasmic protein GE198_RS03090 ENOG4105D22 carbon starvation protein GE198_RS03100 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase GE198_RS03105 ENOG4105WQI isochorismatase GE198_RS03110 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase GE198_RS03115 ENOG4105E4F Isochorismate synthase GE198_RS03120 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein GE198_RS03130 ENOG4105DQ5 transport system permease protein GE198_RS03135 ENOG4105TVJ transport system, permease GE198_RS03140 ENOG4105E0A ABC, transporter GE198_RS03145 ENOG4108QY5 Ferric enterobactin transport protein GE198_RS03150 ENOG4105C0W non-ribosomal peptide synthetase GE198_RS03155 ENOG41085A6 mbth domain-containing protein GE198_RS03160 ENOG4105E93 esterase GE198_RS03165 ENOG4107RNH Outer membrane receptor FepA GE198_RS03170 ENOG4108TSE Transferase GE198_RS03180 ENOG4105WQ6 Membrane GE198_RS03185 ENOG4105HFT AraC family transcriptional regulator GE198_RS03190 ENOG41067SE Tetr family transcriptional regulator GE198_RS03195 ENOG4105MSB protein, conserved in bacteria GE198_RS03200 ENOG4108RCM Nitroreductase GE198_RS03220 ENOG4105F3R pts system mannose fructose sorbose family iid GE198_RS03230 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine GE198_RS03235 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GE198_RS03245 ENOG4105CUY Mechanosensitive ion channel GE198_RS03250 ENOG4105C85 amino acid GE198_RS03260 ENOG4108KBJ Inner membrane protein YkgB GE198_RS03265 ENOG41066GK UPF0379 protein ykgI GE198_RS03270 ENOG4107QN2 dihydrolipoyl dehydrogenase GE198_RS03275 ENOG4108K01 transcriptional regulator GE198_RS03280 ENOG4105EXC Acyl-transferase GE198_RS03405 ENOG4105RWQ Protein of unknown function (DUF1364) GE198_RS03440 ENOG4105NY2 NinB protein GE198_RS03460 ENOG4105CDU Replicative dna helicase GE198_RS03530 ENOG4105VIZ double-strand break repair protein GE198_RS03535 ENOG4108UUM single-stranded DNA-binding protein GE198_RS03585 ENOG4108KU3 Integrase GE198_RS03595 ENOG4106KCD HTH_LUXR GE198_RS03605 ENOG4106721 fimbriae Y protein GE198_RS03610 ENOG4108Q9V regulatoR GE198_RS03615 ENOG4108ZI2 Fimbrial protein GE198_RS03620 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) GE198_RS03625 ENOG4105CW0 outer membrane usher protein GE198_RS03630 ENOG4108AF8 Chaperone GE198_RS03640 ENOG4108WDE Fimbrial protein GE198_RS03650 ENOG4105WQ3 Rna-binding protein GE198_RS03655 ENOG4105S2T inner membrane protein YbcI GE198_RS03675 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) GE198_RS03685 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) GE198_RS03690 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit GE198_RS03695 ENOG4105C5B carbamate kinase GE198_RS03700 ENOG4105G5A Protein of unknown function (DUF2877) GE198_RS03705 ENOG4107REC cytoplasmic protein GE198_RS03710 ENOG4107R1Q Membrane protein FdrA GE198_RS03715 ENOG4105DG4 malate L-lactate dehydrogenase GE198_RS03720 ENOG4105CE7 Amidase, hydantoinase carbamoylase family GE198_RS03725 ENOG4105S0E allantoin catabolism protein GE198_RS03730 ENOG4105BZW Glycerate kinase GE198_RS03735 ENOG4105DTE Xanthine uracil vitamin C permease GE198_RS03745 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease GE198_RS03755 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GE198_RS03760 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) GE198_RS03765 ENOG41060W2 glyoxylate carboligase GE198_RS03790 ENOG4108UMI ABC transporter, permease GE198_RS03795 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) GE198_RS03800 ENOG4105D01 (LipO)protein GE198_RS03810 ENOG4105CV6 ABC transporter, permease GE198_RS03815 ENOG4108I0Y (ABC) transporter GE198_RS03820 ENOG4108UJV acyl-CoA thioesterase i GE198_RS03825 ENOG4105E1F short-chain dehydrogenase reductase GE198_RS03830 ENOG4107QR8 Thioredoxin GE198_RS03835 ENOG4105C4B ABC transporter, permease GE198_RS03840 ENOG41083J0 (ABC) transporter GE198_RS03845 ENOG4107QX8 SPFH domain, Band 7 family protein GE198_RS03850 ENOG4105G5H Membrane GE198_RS03855 ENOG4108Z6Z Transcriptional regulator GE198_RS03860 ENOG4105C59 p-type ATPase GE198_RS03870 ENOG4105MBR gumn family GE198_RS03875 ENOG4108Z66 YbaK ebsC protein GE198_RS03880 ENOG4105CGH 5'-nucleotidase GE198_RS03885 ENOG4105EU0 Major facilitator Superfamily GE198_RS03890 ENOG4105CKD glutathione-regulated potassium-efflux system protein GE198_RS03895 ENOG4107RE1 Inosine-guanosine kinase GE198_RS03930 ENOG4107QMP dna polymerase iii subunits gamma and tau GE198_RS03940 ENOG4105WD1 Membrane GE198_RS03945 ENOG4108URS primosomal replication protein n'' GE198_RS03950 ENOG4106428 Protein of unknown function (DUF2496) GE198_RS03955 ENOG4105DNE Transposase GE198_RS03960 ENOG4105EGS Mechanosensitive ion channel GE198_RS03965 ENOG4107XI7 Tetr family transcriptional regulator GE198_RS03970 ENOG4105C1P efflux transporter, rnd family, mfp subunit GE198_RS03975 ENOG4105BZS acriflavin resistance protein GE198_RS03980 ENOG4108UKR Biofilm formation regulator YbaJ GE198_RS03990 ENOG4108UW5 maltose o-acetyltransferase GE198_RS03995 ENOG4105GSJ Inner membrane protein ylaC GE198_RS04010 ENOG41066DG (EAL) domain protein GE198_RS04020 ENOG41080UX Methyltransferase GE198_RS04025 ENOG4108MNP Glycoprotein polysaccharide metabolism GE198_RS04030 ENOG4105C29 acyl-CoA thioesterase GE198_RS04035 ENOG4105BZU Histidine kinase GE198_RS04040 ENOG4108YZA Nitrogen regulatory protein pii GE198_RS04045 ENOG4105BZ1 (ABC) transporter GE198_RS04050 ENOG4105BZ1 (ABC) transporter GE198_RS04055 ENOG4108XM1 transcriptional regulator AsnC family GE198_RS04070 ENOG4108NFA extracellular solute-binding protein GE198_RS04080 ENOG4108TGP Thioesterase superfamily protein GE198_RS04085 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein GE198_RS04090 ENOG4105EIN peptidylprolyl cis-trans isomerase GE198_RS04095 ENOG4105K70 DNA-binding protein GE198_RS04100 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) GE198_RS04120 ENOG4105M85 Bola protein GE198_RS04125 ENOG4105IEY (LipO)protein GE198_RS04130 ENOG4105EYM Major Facilitator superfamily GE198_RS04135 ENOG4105E2S oxidase) subunit II GE198_RS04140 ENOG4105BZ9 Cytochrome C oxidase, subunit I GE198_RS04145 ENOG4105CCU oxidase (Subunit III) GE198_RS04150 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) GE198_RS04170 ENOG4107RDB Major Facilitator GE198_RS04180 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) GE198_RS04185 ENOG4107S0N DJ-1 family GE198_RS04190 ENOG4108KAZ Involved in phosphonate degradation (By similarity) GE198_RS04200 ENOG4106S9K Transcriptional regulator GE198_RS04210 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GE198_RS04220 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component GE198_RS04230 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) GE198_RS04235 ENOG4105CTB Polyprenyl synthetase GE198_RS04245 ENOG4105CPC Aldo Keto reductase GE198_RS04250 ENOG4108ZAI phosphatidylglycerophosphatase a GE198_RS04255 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) GE198_RS04260 ENOG4107YIM Involved in the transcription termination process (By similarity) GE198_RS04270 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) GE198_RS04280 ENOG4108KIC (LipO)protein GE198_RS04285 ENOG4105DRB nucleoside-specific channel-forming protein GE198_RS04295 ENOG4105N1F Hnh endonuclease GE198_RS04310 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) GE198_RS04320 ENOG4105VIE preprotein translocase, subunit YajC GE198_RS04340 ENOG4105D3R alkyl hydroperoxide reductase GE198_RS04345 ENOG4107R28 alpha amylase, catalytic region GE198_RS04350 ENOG4105C85 amino acid GE198_RS04355 ENOG4105CWM branched-chain amino acid transport system II carrier protein GE198_RS04360 ENOG4105BZU Histidine kinase GE198_RS04365 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GE198_RS04370 ENOG4107RH8 nuclease SbcCD subunit D GE198_RS04375 ENOG4105EYH Exonuclease GE198_RS04380 ENOG4105F27 Major Facilitator GE198_RS04385 ENOG4105DKQ ROK family GE198_RS04400 ENOG4105HBA AroM protein GE198_RS04405 ENOG4105SS3 GE198_RS04420 ENOG4105II7 pyrroline-5-carboxylate reductase GE198_RS04425 ENOG4105BZU Histidine kinase GE198_RS04430 ENOG4105VIF phosphate starvation-inducible protein GE198_RS04450 ENOG4105CPF Cell wall formation (By similarity) GE198_RS04455 ENOG4105UNH Membrane GE198_RS04460 ENOG4105FR5 inner membrane protein YaiY GE198_RS04465 ENOG4107QS8 (LipO)protein GE198_RS04470 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 GE198_RS04475 ENOG4107R6D beta-lactam binding protein AmpH GE198_RS04480 ENOG4108PNB DNA-binding transcriptional regulator GE198_RS04485 ENOG4108NSE outer membrane autotransporter barrel GE198_RS04490 ENOG4105D52 delta-aminolevulinic acid dehydratase GE198_RS04495 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GE198_RS04500 ENOG4105DXD 2-methylcitrate dehydratase GE198_RS04505 ENOG4105BZN citrate synthase GE198_RS04510 ENOG4105CR4 methylisocitrate lyase GE198_RS04515 ENOG4108JU7 Transcriptional regulator GE198_RS04520 ENOG4105TDT uncharacterized protein yahO GE198_RS04525 ENOG4105E82 cytochrome subunit of dehydrogenase GE198_RS04545 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GE198_RS04550 ENOG4105C4M (Ubiquinol oxidase) subunit I GE198_RS04560 ENOG4105D8D Type III GE198_RS04565 ENOG4107QMH DNA methylase GE198_RS04570 ENOG4105JHE Major Facilitator Superfamily GE198_RS04600 ENOG4105ENJ RND efflux system, outer membrane lipoprotein GE198_RS04620 ENOG4108T1M outer membrane protein x GE198_RS04635 ENOG4107XTP (EAL) domain protein GE198_RS04650 ENOG4105X0I Fimbrial GE198_RS04655 ENOG4108VEV chaperone GE198_RS04660 ENOG4105CW0 outer membrane usher protein GE198_RS04685 ENOG4105EJC lysr family transcriptional regulator GE198_RS04695 ENOG4105ERH Fumarylacetoacetate hydrolase GE198_RS04700 ENOG4108TFY Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) GE198_RS04705 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) GE198_RS04710 ENOG4105D94 Major Facilitator Superfamily GE198_RS04715 ENOG4105V2F Uncharacterized protein yoac GE198_RS04720 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit GE198_RS04725 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit GE198_RS04745 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) GE198_RS04755 ENOG4105FCK Membrane GE198_RS04770 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) GE198_RS04775 ENOG4105CIN aminoacyl-histidine dipeptidase GE198_RS04780 ENOG4108S2Y peptide Chain Release factor GE198_RS04795 ENOG4105F7V ErfK ybiS ycfS ynhG family protein GE198_RS04800 ENOG4105E7A Glutamine amidotransferase GE198_RS04810 ENOG4107QPN acyl-Coa dehydrogenase GE198_RS04815 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GE198_RS04825 ENOG4105T40 surface antigen msp4 family protein GE198_RS04835 ENOG4105W7K Transcriptional regulator GE198_RS04920 ENOG4105CNA YD repeat protein GE198_RS05020 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GE198_RS05060 ENOG4107RZZ dna polymerase iii epsilon subunit GE198_RS05065 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) GE198_RS05070 ENOG4105D1A Methyltransferase GE198_RS05080 ENOG4105E9H Lytic Murein transglycosylase GE198_RS05085 ENOG4105F2W methyltransferase GE198_RS05095 ENOG4105F27 Major Facilitator GE198_RS05100 ENOG4105HEI LysR family (Transcriptional regulator GE198_RS05105 ENOG4105CV8 reductase GE198_RS05140 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase GE198_RS05145 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) GE198_RS05150 ENOG4108UMI ABC transporter, permease GE198_RS05155 ENOG4105D01 (LipO)protein GE198_RS05160 ENOG4108R8X outer membrane lipoprotein GE198_RS05165 ENOG4108R96 Methyltransferase, YaeB family GE198_RS05175 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion GE198_RS05180 ENOG4108YZN class I peptide chain release factor GE198_RS05185 ENOG4108VWS Yaeq family GE198_RS05195 ENOG4105M1T rho-binding antiterminator GE198_RS05205 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase GE198_RS05210 ENOG4105CXN decarboxylase GE198_RS05215 ENOG4108M1A Chitin-binding protein GE198_RS05225 ENOG4105C0B DNA polymerase III (alpha subunit) GE198_RS05245 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) GE198_RS05250 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) GE198_RS05255 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) GE198_RS05270 ENOG4105KNE Phosphatidate cytidylyltransferase GE198_RS05285 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) GE198_RS05290 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) GE198_RS05300 ENOG4105CE9 30S ribosomal protein S2 GE198_RS05305 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) GE198_RS05315 ENOG4105DMJ Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity) GE198_RS05320 ENOG4105CSH Transporter GE198_RS05330 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR GE198_RS05335 ENOG4105C0H protease GE198_RS05350 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) GE198_RS05355 ENOG4105EN6 Membrane GE198_RS05360 ENOG4108YX9 iron--sulfur cluster insertion protein erpA GE198_RS05365 ENOG4105CMQ Chloride channel GE198_RS05370 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase GE198_RS05375 ENOG4106RDH Protein of unknown function (DUF2544) GE198_RS05385 ENOG4105UGQ Fimbrial GE198_RS05390 ENOG4105NEV Fimbrial GE198_RS05395 ENOG4108FZ9 Chaperone GE198_RS05400 ENOG4106PG1 outer membrane usher protein GE198_RS05410 ENOG4105S6R Iron-hydroxamate transporter permease subunit GE198_RS05415 ENOG4105J76 Periplasmic binding protein GE198_RS05420 ENOG4105E0A ABC, transporter GE198_RS05425 ENOG4105E0K tonB-dependent siderophore receptor GE198_RS05430 ENOG4105BZ4 penicillin-binding protein GE198_RS05435 ENOG4105CQ7 ATP-dependent helicase GE198_RS05440 ENOG4107XID 2'-5' rna ligase GE198_RS05450 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters GE198_RS05455 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) GE198_RS05460 ENOG4105DJ0 Poly(A) Polymerase GE198_RS05465 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase GE198_RS05475 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) GE198_RS05485 ENOG4107BJW polysaccharide deacetylase GE198_RS05490 ENOG4108YTN IIa component GE198_RS05500 ENOG4108UIF Chaperone GE198_RS05505 ENOG4105CW0 outer membrane usher protein GE198_RS05510 ENOG4108MDY Fimbrial GE198_RS05515 ENOG4105E3A (ABC) transporter GE198_RS05520 ENOG4105DA5 (ABC) transporter GE198_RS05525 ENOG41077A9 carbonic anhydrase GE198_RS05530 ENOG4108UGV hypoxanthine phosphoribosyltransferase GE198_RS05535 ENOG4105DZG Dehydrogenase GE198_RS05540 ENOG4105E3B Multicopper oxidase GE198_RS05545 ENOG4108ZRK uncharacterized protein yacC GE198_RS05560 ENOG4105MVE transcriptional regulator GE198_RS05565 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) GE198_RS05570 ENOG4107S2N Type III effector Hrp-dependent GE198_RS05575 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) GE198_RS05590 ENOG4106HGK Inner membrane protein yieI GE198_RS05595 ENOG4107QIJ Aconitate hydratase 2 GE198_RS05600 ENOG4108NST exported protein GE198_RS05615 ENOG4107QN2 dihydrolipoyl dehydrogenase GE198_RS05620 ENOG4107QSN dihydrolipoamide acetyltransferase GE198_RS05625 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) GE198_RS05640 ENOG4105CT4 transporter GE198_RS05645 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) GE198_RS05650 ENOG4106A72 regulatory protein AmpE GE198_RS05660 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase GE198_RS05665 ENOG4108ZUW Major pilin subunit GE198_RS05670 ENOG4107QHF type ii secretion system protein e GE198_RS05675 ENOG4105D7Q type ii secretion system GE198_RS05685 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) GE198_RS05705 ENOG4105M6F mutator MutT protein GE198_RS05725 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) GE198_RS05730 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) GE198_RS05735 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) GE198_RS05755 ENOG4105CNI cell division protein FtsW GE198_RS05765 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) GE198_RS05770 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) GE198_RS05780 ENOG4105CJN penicillin-binding protein GE198_RS05785 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) GE198_RS05800 ENOG4107B7Y DNA-binding transcriptional regulator FruR GE198_RS05805 ENOG4108ZP8 Acetolactate synthase small subunit GE198_RS05810 ENOG4105C7K acetolactate synthase GE198_RS05815 ENOG41064T2 transcriptional regulator, lysR family GE198_RS05875 ENOG4108KF1 Membrane GE198_RS05880 ENOG41063TF transcriptional regulator (AraC GE198_RS05895 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase GE198_RS05915 ENOG4105CQ2 DNA polymerase GE198_RS05925 ENOG4105D3G Pseudouridine synthase GE198_RS05935 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) GE198_RS05945 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) GE198_RS05955 ENOG4105NWN ApaG protein GE198_RS05975 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF GE198_RS05995 ENOG4105M5B (LipO)protein GE198_RS06000 ENOG4105C54 Major Facilitator superfamily GE198_RS06005 ENOG4105WQV ferredoxin-like protein GE198_RS06010 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GE198_RS06055 ENOG4108XNW Transcriptional activatory protein CaiF GE198_RS06060 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain GE198_RS06065 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain GE198_RS06090 ENOG4105CHY citrate lyase, alpha GE198_RS06095 ENOG4105CI0 Citrate lyase GE198_RS06105 ENOG4105DUA (citrate (pro-3S)-lyase ligase GE198_RS06120 ENOG4107QSA Oxaloacetate decarboxylase GE198_RS06125 ENOG4105D9Q decarboxylase (Beta subunit) GE198_RS06130 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism GE198_RS06135 ENOG4106YYS transcriptional regulatory protein GE198_RS06155 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase GE198_RS06170 ENOG4105DTN riboflavin biosynthesis protein ribF GE198_RS06175 ENOG410647N response to DNA damage stimulus GE198_RS06195 ENOG41063Z6 transcriptional regulator, lysR family GE198_RS06215 ENOG4105C4X radical SAM domain protein GE198_RS06220 ENOG41061MV Arylsulfatase GE198_RS06230 ENOG4105CGH 5'-nucleotidase GE198_RS06245 ENOG4105DQS Transcriptional regulator GE198_RS06265 ENOG4106PH7 chaperone GE198_RS06280 ENOG4105MHR Fimbrial protein GE198_RS06290 ENOG4108AF8 Chaperone GE198_RS06345 ENOG4108WTA UPF0412 protein YaaI GE198_RS06350 ENOG4108QUJ UPF0174 protein YaaW GE198_RS06355 ENOG4106HK8 GPR1 FUN34 yaaH family protein GE198_RS06360 ENOG4108RIR Molybdenum cofactor biosynthesis protein GE198_RS06365 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GE198_RS06370 ENOG4105BZG amino acid carrier protein GE198_RS06380 ENOG4105D98 threonine synthase GE198_RS06390 ENOG4105CFH Aspartokinase GE198_RS06400 ENOG4106FVC RNA methyltransferase GE198_RS06405 ENOG410759A GE198_RS06410 ENOG41065U4 response regulator GE198_RS06420 ENOG4108PNB DNA-binding transcriptional regulator GE198_RS06430 ENOG4108VCD Chaperone GE198_RS06435 ENOG4105CW0 outer membrane usher protein GE198_RS06450 ENOG4105CT7 inner membrane cred family protein GE198_RS06455 ENOG4105EB3 Histidine kinase GE198_RS06460 ENOG4105E3W Two component transcriptional regulator (Winged helix family GE198_RS06465 ENOG4108RH0 Crea protein GE198_RS06470 ENOG4105UEI Transcriptional Regulator AraC Family GE198_RS06490 ENOG4107SC1 transglycosylase GE198_RS06495 ENOG4105C5H ABC transporter GE198_RS06500 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase GE198_RS06505 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) GE198_RS06510 ENOG4105EAC phosphoserine phosphatase GE198_RS06515 ENOG41062Z9 Membrane GE198_RS06530 ENOG4105UMR response to DNA damage stimulus GE198_RS06535 ENOG4108S1B Periplasmic chaperone protein GE198_RS06540 ENOG4105E6S usher protein( GE198_RS06570 ENOG4105G0K glycine radical enzyme YjjI family GE198_RS06575 ENOG41076CZ activating enzyme GE198_RS06580 ENOG4105EYA deoxyribonuclease GE198_RS06585 ENOG4108NRW Phospholipase, patatin family GE198_RS06595 ENOG4105K3G Periplasmic Protein GE198_RS06605 ENOG4105PAD Hydrolase GE198_RS06610 ENOG4105KEG ribosomal-protein-alanine acetyltransferase GE198_RS06615 ENOG4108WPU DNA polymerase III subunit psi GE198_RS06640 ENOG4105YBH Protein of unknown function (DUF1435) GE198_RS06645 ENOG4105BZU Histidine kinase GE198_RS06650 ENOG4108819 ferric iron reductase GE198_RS06655 ENOG4108UIN ybak prolyl-trna synthetase associated region GE198_RS06660 ENOG4108T94 DNA-binding transcriptional activator BglJ GE198_RS06665 ENOG4108N8T regulatoR GE198_RS06670 ENOG4105DWK Membrane GE198_RS06685 ENOG4106CVF DNA replication protein GE198_RS06690 ENOG4105RI1 glycoprotein receptor GE198_RS06700 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) GE198_RS06705 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) GE198_RS06710 ENOG4105F3R pts system mannose fructose sorbose family iid GE198_RS06715 ENOG4105ETZ PTS System GE198_RS06720 ENOG4108IQ3 PTS system GE198_RS06735 ENOG4105C8Q Methyl-accepting chemotaxis GE198_RS06740 ENOG4105D22 carbon starvation protein GE198_RS06745 ENOG4105VCD cytoplasmic protein GE198_RS06750 ENOG4105CKI cobalamin synthesis protein GE198_RS06765 ENOG4106H3A restriction GE198_RS06770 ENOG4107SCJ type I restriction enzyme EcoKI subunit R GE198_RS06775 ENOG4105CVR type I restriction-modification system GE198_RS06785 ENOG4105FU6 Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease La (By similarity) GE198_RS06805 ENOG4105C26 Dehydrogenase GE198_RS06810 ENOG4105DNE Transposase GE198_RS06815 ENOG41083G8 Multidrug resistance protein MdtM GE198_RS06820 ENOG4106BRA Membrane GE198_RS06825 ENOG4105CBP Major Facilitator GE198_RS06830 ENOG41074DU domain protein GE198_RS06835 ENOG4108P2H Inner membrane protein YjiG GE198_RS06840 ENOG4105DYB Isoaspartyl dipeptidase GE198_RS06845 ENOG4107YNJ LysR family Transcriptional regulator GE198_RS06865 ENOG4105C6F GntR Family Transcriptional Regulator GE198_RS06890 ENOG4105KZM cytoplasmic protein GE198_RS06900 ENOG4105DTA methyltransferase GE198_RS06905 ENOG4105CDY transcriptional regulatory protein GE198_RS07020 ENOG4105DQ4 alcohol dehydrogenase GE198_RS07025 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family GE198_RS07030 ENOG4105CPQ Dehydrogenase GE198_RS07035 ENOG4105CHR reductase GE198_RS07040 ENOG4105C6Z Gluconate GE198_RS07045 ENOG4105K2J Transcriptional regulator GE198_RS07050 ENOG4108K5H permease YjgP YjgQ family protein GE198_RS07055 ENOG4108M8S permease YjgP YjgQ family protein GE198_RS07065 ENOG4105MYG DNA polymerase iii, chi subunit GE198_RS07070 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) GE198_RS07075 ENOG4108M3P Membrane GE198_RS07080 ENOG4108MJ3 acetyltransferase GE198_RS07090 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase GE198_RS07095 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) GE198_RS07100 ENOG4105DBV ornithine carbamoyltransferase GE198_RS07105 ENOG4105XEP YhcH YjgK YiaL family protein GE198_RS07110 ENOG4105CEU Arginine dihydrolase GE198_RS07115 ENOG4105C5B carbamate kinase GE198_RS07120 ENOG4105DBV ornithine carbamoyltransferase GE198_RS07125 ENOG4105CSX c4-dicarboxylate anaerobic carrier GE198_RS07130 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) GE198_RS07140 ENOG41077AM PyrBI operon attenuator GE198_RS07155 ENOG4105KME endoribonuclease L-psp GE198_RS07175 ENOG4105D4X repressor GE198_RS07180 ENOG4105C5Y PTS System GE198_RS07185 ENOG4105CG3 alpha amylase, catalytic region GE198_RS07190 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase GE198_RS07195 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) GE198_RS07200 ENOG4105K4U addiction module toxin, RelE StbE family GE198_RS07210 ENOG4105EMD TRANSCRIPTIONal GE198_RS07225 ENOG41069H0 dihydroorotase EC 3.5.2.3 GE198_RS07255 ENOG4108XVM Cytochrome b(562) GE198_RS07260 ENOG4105CMS peptidase U62, modulator of DNA gyrase GE198_RS07270 ENOG4105DFU Cell wall formation (By similarity) GE198_RS07280 ENOG4105F0N pyrophosphate phospho-hydrolase GE198_RS07285 ENOG41069H0 dihydroorotase EC 3.5.2.3 GE198_RS07290 ENOG4105DJB Major Facilitator Superfamily GE198_RS07295 ENOG4108ZHD aig2 family GE198_RS07315 ENOG4105C37 (CBS) domain GE198_RS07320 ENOG41061GZ Protein of unknown function (DUF1107) GE198_RS07325 ENOG4108UUE Transcriptional regulator GE198_RS07330 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase GE198_RS07335 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic GE198_RS07340 ENOG4105KVH Transcriptional regulator GE198_RS07345 ENOG4105ECR NmrA family GE198_RS07350 ENOG4105DXC membrane GE198_RS07365 ENOG4108V1T peptidylprolyl cis-trans isomerase GE198_RS07370 ENOG4105FHY Opacity-associated protein A GE198_RS07385 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) GE198_RS07390 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) GE198_RS07395 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) GE198_RS07405 ENOG4105KIT UPF0379 protein yjfY GE198_RS07435 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC GE198_RS07450 ENOG4108MXZ Esterase GE198_RS07455 ENOG4105WSB biofilm stress and motility protein A GE198_RS07460 ENOG4105S17 UPF0379 protein yjfN GE198_RS07465 ENOG4105CSU acyl-Coa dehydrogenase GE198_RS07470 ENOG4106032 Glutathionylspermidine synthase GE198_RS07475 ENOG4108KXT Conserved Protein GE198_RS07480 ENOG4105Z6B inner membrane protein yjfl GE198_RS07485 ENOG4107VNS Protein of unknown function (DUF2491) GE198_RS07495 ENOG4108P9J Phage shock protein A GE198_RS07500 ENOG4105FUX Conserved Protein GE198_RS07505 ENOG4105C2N RNA methyltransferase TrmH family group 3 GE198_RS07510 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) GE198_RS07530 ENOG4105EPW hflc protein GE198_RS07535 ENOG4107QJR hflk protein GE198_RS07540 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) GE198_RS07545 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) GE198_RS07560 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GE198_RS07565 ENOG4105K8N protein family UPF0079, ATPase GE198_RS07570 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) GE198_RS07575 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) GE198_RS07595 ENOG4106TNF Periplasmic binding protein GE198_RS07600 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) GE198_RS07615 ENOG4105EGS Mechanosensitive ion channel GE198_RS07620 ENOG4106CG8 Inner membrane protein YjeO GE198_RS07625 ENOG4107SC7 Inner membrane transporter yjeM GE198_RS07635 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) GE198_RS07640 ENOG4105E33 succinate dehydrogenase GE198_RS07650 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) GE198_RS07660 ENOG4105KPY Small multidrug resistance protein GE198_RS07670 ENOG4106BSU Entericidin B GE198_RS07680 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) GE198_RS07685 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein GE198_RS07690 ENOG4105MTB Uncharacterized protein YjeJ GE198_RS07695 ENOG4108ZVF (LipO)protein GE198_RS07710 ENOG4105DVH amino acid GE198_RS07715 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 GE198_RS07720 ENOG4108IJ0 Aspartate ammonia-lyase GE198_RS07725 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GE198_RS07735 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) GE198_RS07740 ENOG4108SIC Transcriptional regulator GE198_RS07755 ENOG4105SBG acid phosphatase GE198_RS07850 ENOG41068CG regulatoR GE198_RS07865 ENOG4108ZK4 sdia-regulated domain-containing protein GE198_RS07875 ENOG4108NEM leader-binding protein dmsD GE198_RS07880 ENOG4107KGK dmso reductase anchor subunit GE198_RS07885 ENOG4105QAX Iron-sulfur GE198_RS07890 ENOG4107QY8 reductase GE198_RS07895 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism GE198_RS07900 ENOG4108MRH transcriptional regulatory protein GE198_RS07910 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GE198_RS07915 ENOG4107GFK fumarate GE198_RS07920 ENOG4105CT4 transporter GE198_RS07925 ENOG4105F8D glycoside hydrolase family 4 GE198_RS07930 ENOG4108K2B transcriptional regulator GE198_RS07935 ENOG4105CXN decarboxylase GE198_RS07940 ENOG4106ZGR Transcriptional regulator GE198_RS07945 ENOG4105D5Q Arginine ornithine antiporter GE198_RS07950 ENOG4105DIJ Phosphoethanolamine transferase GE198_RS07955 ENOG4105XJC Two component transcriptional regulator (Winged helix family GE198_RS07960 ENOG4105ECM Sensor protein basS pmrB GE198_RS07970 ENOG4105CSH Transporter GE198_RS07975 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA GE198_RS07980 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase GE198_RS07985 ENOG410870W N-acetyltransferase GE198_RS08000 ENOG41082ND Uncharacterized protein yjcO GE198_RS08005 ENOG4105CK2 sodium dicarboxylate symporter GE198_RS08010 ENOG4108W0S formate-dependent nitrite reductase complex GE198_RS08020 ENOG4108QKW cytochrome c-type biogenesis protein GE198_RS08025 ENOG4105DVI reductase, NrfD GE198_RS08030 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GE198_RS08035 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit GE198_RS08045 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GE198_RS08050 ENOG41062QD Membrane GE198_RS08055 ENOG4107QN1 sodium solute GE198_RS08060 ENOG41067MG lrgb family GE198_RS08070 ENOG4105CMU LysR family (Transcriptional regulator GE198_RS08075 ENOG4105EEQ Na H antiporter GE198_RS08080 ENOG4105C7N Xanthine uracil vitamin C permease GE198_RS08090 ENOG4108Z4X TRANSCRIPTIONal GE198_RS08095 ENOG4108W3Q Transcriptional regulator GE198_RS08100 ENOG4108M8H domain protein GE198_RS08105 ENOG4105PMV Membrane GE198_RS08140 ENOG4108UUM single-stranded DNA-binding protein GE198_RS08145 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) GE198_RS08160 ENOG4105MSB protein, conserved in bacteria GE198_RS08165 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme GE198_RS08170 ENOG4105F0S class B acid phosphatase GE198_RS08175 ENOG4105CGF Aromatic amino acid aminotransferase GE198_RS08180 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GE198_RS08185 ENOG4105CDU Replicative dna helicase GE198_RS08190 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein GE198_RS08195 ENOG4105P4Z Phage shock protein G GE198_RS08200 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GE198_RS08210 ENOG4105MYN Zinc uptake regulation protein GE198_RS08215 ENOG4105VDW Csbd family GE198_RS08225 ENOG4107R73 Mate efflux family protein GE198_RS08230 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) GE198_RS08235 ENOG41080IJ Diacylglycerol kinase GE198_RS08255 ENOG4107W52 maltose operon periplasmic protein GE198_RS08265 ENOG4108IJ9 (ABC) transporter GE198_RS08270 ENOG4107FKK extracellular solute-binding protein family 1 GE198_RS08275 ENOG4105D56 permease protein GE198_RS08280 ENOG4105EG2 ABC transporter, permease GE198_RS08290 ENOG4105E3R (LipO)protein GE198_RS08295 ENOG4108Q9C Periplasmic Protein GE198_RS08300 ENOG4108MDC (LipO)protein GE198_RS08315 ENOG4105CFH Aspartokinase GE198_RS08395 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) GE198_RS08400 ENOG4105CKK Glycosyl transferase, family 2 GE198_RS08425 ENOG4108X9F tail fiber protein GE198_RS08430 ENOG4105UZW Tail fiber assembly protein GE198_RS08445 ENOG4108KP7 hydrolase GE198_RS08450 ENOG4105E98 transcriptional regulator DeoR family GE198_RS08455 ENOG4108ZR5 Conserved Protein GE198_RS08460 ENOG4105FE9 pseudouridine synthase GE198_RS08465 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme GE198_RS08480 ENOG4105EAM Na Pi-cotransporter GE198_RS08485 ENOG4105C3R Methionine synthase GE198_RS08490 ENOG41069M3 Transcriptional regulator GE198_RS08505 ENOG4108I9X Isocitrate lyase GE198_RS08510 ENOG4107QP3 malate synthase g GE198_RS08520 ENOG4105K5X acetyltransferase GE198_RS08550 ENOG4105C12 Phosphoribosylglycinamide synthetase GE198_RS08555 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GE198_RS08560 ENOG4105BZU Histidine kinase GE198_RS08570 ENOG4108T8B Protein of unknown function (DUF1481) GE198_RS08575 ENOG4105K70 DNA-binding protein GE198_RS08580 ENOG4105R2J Conserved Protein GE198_RS08615 ENOG4105D06 uba thif-type nad fad binding protein GE198_RS08620 ENOG4105WHD thiamine biosynthesis protein ThiS GE198_RS08630 ENOG4105D41 biosynthesis protein thiH GE198_RS08650 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) GE198_RS08655 ENOG4107QIH DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) GE198_RS08660 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) GE198_RS08665 ENOG4108VZM 50s ribosomal protein L10 GE198_RS08680 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) GE198_RS08685 ENOG4105PM1 preprotein translocase subunit SecE GE198_RS08690 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) GE198_RS08725 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase GE198_RS08775 ENOG4108Y73 Membrane GE198_RS08790 ENOG4105C5Q Transcriptional regulator GE198_RS08820 ENOG4105DIJ Phosphoethanolamine transferase GE198_RS08825 ENOG4106R3P AraC family transcriptional regulator GE198_RS08835 ENOG4105DCT glycerol dehydrogenase GE198_RS08840 ENOG4108XC3 NADH ubiquinone oxidoreductase GE198_RS08850 ENOG4105SYT Methylenetetrahydrofolate reductase GE198_RS08855 ENOG4105CGH 5'-nucleotidase GE198_RS08870 ENOG4105D64 Mechanosensitive ion channel GE198_RS08875 ENOG4105CFH Aspartokinase GE198_RS08880 ENOG4105C28 cystathionine GE198_RS08890 ENOG4108MR7 Arylsulfotransferase GE198_RS08905 ENOG4105C25 Primosomal protein n' GE198_RS08910 ENOG4105ETE Transcriptional regulator (LacI family GE198_RS08915 ENOG41063M6 Cell Division Protein GE198_RS08930 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase GE198_RS08945 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) GE198_RS08955 ENOG4105CBT Fructose-1,6-bisphosphatase GE198_RS08960 ENOG4105DP0 ferredoxin-NADP reductase GE198_RS08965 ENOG4108VTS Membrane GE198_RS08970 ENOG4105EBK exported protein GE198_RS08995 ENOG4105D4B ABC, transporter GE198_RS09010 ENOG4105C2J ABC transporter GE198_RS09020 ENOG4107RYS Autoinducer-2 (AI-2) kinase GE198_RS09030 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) GE198_RS09050 ENOG4105D7K pfkb domain protein GE198_RS09055 ENOG4105CT4 transporter GE198_RS09065 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein GE198_RS09070 ENOG4105CTQ phosphohexokinase GE198_RS09080 ENOG4105FMW periplasmic GE198_RS09085 ENOG4105E3W Two component transcriptional regulator (Winged helix family GE198_RS09090 ENOG4105E0F Histidine kinase GE198_RS09100 ENOG4108RPX mosc domain containing protein GE198_RS09105 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GE198_RS09110 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit GE198_RS09115 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter GE198_RS09120 ENOG4105CG6 trap dicarboxylate transporter dctm subunit GE198_RS09125 ENOG4108QGT oligogalacturonate-specific porin GE198_RS09160 ENOG4105C0A alcohol dehydrogenase GE198_RS09175 ENOG4108UMN azlc family GE198_RS09185 ENOG4108V87 frv operon regulatory protein GE198_RS09190 ENOG4108V87 frv operon regulatory protein GE198_RS09205 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GE198_RS09210 ENOG4108MG3 formate dehydrogenase GE198_RS09225 ENOG41068KX affects formate dehydrogenase-N GE198_RS09235 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) GE198_RS09240 ENOG4108Z3N Transcriptional regulator GE198_RS09245 ENOG4105SUU thioesterase domain GE198_RS09260 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 GE198_RS09265 ENOG4105E98 transcriptional regulator DeoR family GE198_RS09270 ENOG4108MGF sugar kinase GE198_RS09275 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GE198_RS09280 ENOG4105D2M Aldolase GE198_RS09285 ENOG4107QKS N-acylglucosamine 2-epimerase GE198_RS09290 ENOG4107WI4 Aldose-1-epimerase GE198_RS09295 ENOG4105CJQ hydrolase, family 31 GE198_RS09300 ENOG4105CT4 transporter GE198_RS09305 ENOG4105CT4 transporter GE198_RS09310 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is GE198_RS09320 ENOG4105CI3 gtp-binding protein typa GE198_RS09325 ENOG4105C5F glutamine synthetase GE198_RS09330 ENOG4105CUX Signal transduction histidine kinase GE198_RS09335 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GE198_RS09340 ENOG4106FIY GE198_RS09345 ENOG4105D4P Coproporphyrinogen iii oxidase GE198_RS09365 ENOG4105C2M dna polymerase I GE198_RS09370 ENOG4106HNH Acyl-transferase GE198_RS09375 ENOG4108Z33 Thiol disulfide Interchange Protein GE198_RS09385 ENOG4105PC1 Conserved Protein GE198_RS09390 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) GE198_RS09395 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b GE198_RS09425 ENOG4108RR8 protoporphyrinogen oxidase GE198_RS09430 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) GE198_RS09435 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein GE198_RS09450 ENOG4105CHU acetyl-coa acetyltransferase GE198_RS09455 ENOG4108MR7 Arylsulfotransferase GE198_RS09460 ENOG4107QK7 reductase GE198_RS09465 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) GE198_RS09470 ENOG4105MDZ Transcriptional activator rfaH GE198_RS09475 ENOG4105F8V Hydrolase, tatD family GE198_RS09480 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) GE198_RS09485 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) GE198_RS09490 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) GE198_RS09500 ENOG4105JC1 sterol-binding domain protein GE198_RS09510 ENOG4105CGY Dna recombination protein GE198_RS09515 ENOG4107SXA Phosphorylase GE198_RS09520 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) GE198_RS09525 ENOG4105C4X radical SAM domain protein GE198_RS09535 ENOG4105DZ2 Transcriptional regulator GE198_RS09540 ENOG4105EMK carboxylate amino acid amine transporter GE198_RS09545 ENOG4105DQF Hydrolase GE198_RS09550 ENOG4108EUD Lysophospholipase GE198_RS09555 ENOG410829K Lysine exporter protein (Lyse ygga) GE198_RS09560 ENOG4105CCF Lysine exporter protein (Lyse ygga) GE198_RS09565 ENOG4105C9U ATP-dependent DNA helicase RecQ GE198_RS09570 ENOG4105HDD phospholipase GE198_RS09575 ENOG4108VUY thioesterase Superfamily protein GE198_RS09580 ENOG4105FR1 rard protein GE198_RS09585 ENOG4106WR8 Inner membrane protein YigG GE198_RS09590 ENOG4105NRM Membrane GE198_RS09595 ENOG4107QUT magnesium and cobalt transport protein CorA GE198_RS09600 ENOG4105C4R Atp-dependent dna helicase GE198_RS09605 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant GE198_RS09610 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GE198_RS09615 ENOG4105CT0 Protein of unknown function, DUF484 GE198_RS09625 ENOG4105S7Z (LipO)protein GE198_RS09640 ENOG4105XQ6 frataxin-like protein GE198_RS09660 ENOG4107T0K Adenylate cyclase GE198_RS09670 ENOG41076E6 Uroporphyrinogen-III Synthase GE198_RS09675 ENOG4105ECF c-methyltransferase GE198_RS09680 ENOG410601J HemY protein GE198_RS09705 ENOG4105C85 amino acid GE198_RS09715 ENOG4105DAD Could be involved in ECA polysaccharide chain elongation (By similarity) GE198_RS09725 ENOG4105EGZ biosynthesis protein GE198_RS09730 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase GE198_RS09735 ENOG4108WJ1 acetyltransferase GE198_RS09740 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) GE198_RS09745 ENOG4105C1B dTDP-glucose 4-6-dehydratase GE198_RS09750 ENOG4108IJ1 Dehydrogenase GE198_RS09755 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase GE198_RS09760 ENOG4105SFE lipopolysaccharide biosynthesis protein GE198_RS09765 ENOG4105ESV Glycosyl transferase, family 4 GE198_RS09770 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) GE198_RS09795 ENOG4105C4R Atp-dependent dna helicase GE198_RS09800 ENOG4106Z1T Nicotinamide Mononucleotide Transporter GE198_RS09805 ENOG4105KQ5 peptidylprolyl cis-trans isomerase GE198_RS09815 ENOG4105EMY transcriptional regulator GE198_RS09830 ENOG4105C7B Threonine dehydratase GE198_RS09840 ENOG4105CM2 brancheD-chain amino acid aminotransferase GE198_RS09845 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit GE198_RS09860 ENOG4105C0P Mg chelatase subunit ChlI GE198_RS09905 ENOG4107EJG GntR family transcriptional regulator GE198_RS09910 ENOG4105C0R drug resistance transporter emrb qaca subfamily GE198_RS09915 ENOG4105ETE Transcriptional regulator (LacI family GE198_RS09920 ENOG4108RVA ribokinase GE198_RS09925 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator GE198_RS09930 ENOG4105CNN ABC, transporter GE198_RS09935 ENOG4105C2J ABC transporter GE198_RS09965 ENOG4108VVK transcriptional Regulator, AsnC GE198_RS09970 ENOG4105QTB Flavodoxin GE198_RS09985 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation GE198_RS10000 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) GE198_RS10020 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) GE198_RS10025 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) GE198_RS10040 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) GE198_RS10045 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) GE198_RS10050 ENOG4105F9E Shikimate 5-dehydrogenase GE198_RS10055 ENOG4105DM4 PTS System GE198_RS10060 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) GE198_RS10065 ENOG4105C8U phosphate abc transporter GE198_RS10070 ENOG4105E2Z phosphate ABC transporter (Permease GE198_RS10075 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GE198_RS10085 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 GE198_RS10090 ENOG4105C7N Xanthine uracil vitamin C permease GE198_RS10095 ENOG4108YYH Nadph-dependent fmn reductase GE198_RS10100 ENOG4105E8Q phosphopantetheinyl transferase GE198_RS10145 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins GE198_RS10160 ENOG4105VG0 50S ribosomal protein l34 GE198_RS10170 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) GE198_RS10180 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GE198_RS10190 ENOG4105CXK mandelate racemase muconate lactonizing GE198_RS10200 ENOG410667J hydrolase GE198_RS10205 ENOG4105EMF GntR family transcriptional regulator GE198_RS10210 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 GE198_RS10215 ENOG4108RTU Aldolase GE198_RS10225 ENOG4105DJB Major Facilitator Superfamily GE198_RS10230 ENOG4105BZU Histidine kinase GE198_RS10235 ENOG4108SV3 Tmao reductase system periplasmic protein tort GE198_RS10240 ENOG4106WF9 DNA-binding transcriptional regulator TorR GE198_RS10245 ENOG4105CUW cytochrome C-TYPE protein GE198_RS10250 ENOG4108EM1 reductase GE198_RS10260 ENOG4105CA0 peroxidase GE198_RS10270 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) GE198_RS10275 ENOG41060IM Heme exporter protein GE198_RS10280 ENOG4105X3C heme exporter protein GE198_RS10290 ENOG4105DA4 cytochrome c-type biogenesis protein GE198_RS10295 ENOG4107QX9 Thiol disulfide interChange protein GE198_RS10300 ENOG4105KWW Biogenesis protein GE198_RS10305 ENOG4105D99 atp gtp-binding protein GE198_RS10310 ENOG4105R2A (LipO)protein GE198_RS10320 ENOG4108SHS Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent (By similarity) GE198_RS10330 ENOG4105VG5 Membrane GE198_RS10335 ENOG4105JP4 Inner membrane protein yidG GE198_RS10340 ENOG4105J13 transcriptional regulator GE198_RS10355 ENOG4105W8I Transcriptional regulator GE198_RS10365 ENOG4105E5M Multidrug resistance protein D GE198_RS10390 ENOG4105C7K acetolactate synthase GE198_RS10395 ENOG4105M71 acetolactate synthase 1 regulatory subunit GE198_RS10400 ENOG4107FB0 transcriptional regulator DeoR family GE198_RS10410 ENOG4105EDR glucose galactose transporter GE198_RS10420 ENOG4108KX4 response regulator GE198_RS10425 ENOG4105BZU Histidine kinase GE198_RS10430 ENOG4105CXY transporter GE198_RS10435 ENOG4105CXY transporter GE198_RS10440 ENOG4108SAJ Protein of unknown function (DUF1198) GE198_RS10455 ENOG41090UW PTS System GE198_RS10460 ENOG4105DT3 PTS system, galactitol-specific IIc component GE198_RS10470 ENOG4105D2N Aldolase GE198_RS10495 ENOG4105CS2 ec 3.2.1.21 GE198_RS10515 ENOG4105DAS pts system GE198_RS10520 ENOG4105ETZ PTS System GE198_RS10525 ENOG4105F3R pts system mannose fructose sorbose family iid GE198_RS10540 ENOG4105DNE Transposase GE198_RS10545 ENOG4108UZ3 Transporter GE198_RS10555 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic GE198_RS10570 ENOG4105CHJ isochorismatase hydrolase GE198_RS10580 ENOG4108TC1 Transcriptional regulator GE198_RS10585 ENOG4105FV3 GE198_RS10595 ENOG4105ISV protein with bipartite regulator domain GE198_RS10610 ENOG4108VEV chaperone GE198_RS10615 ENOG4105CW0 outer membrane usher protein GE198_RS10625 ENOG4105SYG Fimbrial protein GE198_RS10635 ENOG4105P0Q fimbrial-like protein YadC GE198_RS10650 ENOG4105CT4 transporter GE198_RS10655 ENOG4105CJQ hydrolase, family 31 GE198_RS10660 ENOG4105JV1 AsmA family GE198_RS10665 ENOG4105C2W permease GE198_RS10670 ENOG4105D6U Sodium Glutamate Symporter GE198_RS10675 ENOG4105CB5 ATP-dependent DNA helicase recG GE198_RS10680 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase GE198_RS10685 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) GE198_RS10700 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) GE198_RS10705 ENOG4105EN6 Membrane GE198_RS10720 ENOG4105DSJ YicC domain protein GE198_RS10725 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) GE198_RS10745 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase GE198_RS10775 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase GE198_RS10780 ENOG4105DKP glycosyl transferase, family 9 GE198_RS10785 ENOG4107RJ7 Glycosyl transferase (Group 1 GE198_RS10790 ENOG4107543 (lipo)polysaccharide GE198_RS10800 ENOG4107XU6 Glycosyl transferase (Group 1 GE198_RS10805 ENOG4106AH0 Glycosyl Transferase GE198_RS10810 ENOG4105X1N Glycosyl transferase family 8 GE198_RS10815 ENOG4108PDR lipopolysaccharide core biosynthesis protein GE198_RS10820 ENOG4108QD8 lipopolysaccharide core biosynthesis protein GE198_RS10825 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase GE198_RS10830 ENOG4108FRV O-antigen ligase GE198_RS10835 ENOG4105D16 lipopolysaccharide heptosyltransferase i GE198_RS10840 ENOG4105XA0 heptosyltransferase ii GE198_RS10850 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) GE198_RS10860 ENOG4105K64 Glycosyl transferase, family 2 GE198_RS10865 ENOG4105PXI polysaccharide deacetylase GE198_RS10870 ENOG41063SB peptidase GE198_RS10880 ENOG4107YZP Rhodanese domain protein GE198_RS10885 ENOG4105VW4 glutaredoxin 3 GE198_RS10890 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) GE198_RS10895 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase GE198_RS10900 ENOG4105D7W serine acetyltransferase GE198_RS10905 ENOG4105DJB Major Facilitator Superfamily GE198_RS10910 ENOG4105DIA mandelate racemase muconate lactonizing GE198_RS10915 ENOG4105ETE Transcriptional regulator (LacI family GE198_RS10920 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) GE198_RS10930 ENOG41073TP transcriptional regulator GE198_RS10935 ENOG4105DAA L-lactate GE198_RS10940 ENOG4105EUR Domain-Containing protein GE198_RS10945 ENOG4108WY4 inner membrane lipoprotein GE198_RS10950 ENOG4108YYI Protein of unknown function (DUF2810) GE198_RS10960 ENOG4105E61 Mannitol repressor protein GE198_RS10970 ENOG4105CTS PTS system mannitol-specific GE198_RS10975 ENOG4108U78 Glutathione S-transferase GE198_RS10985 ENOG4105EM7 Selenocysteine-specific translation elongation factor GE198_RS10990 ENOG41066F8 ROK family GE198_RS10995 ENOG4105C26 Dehydrogenase GE198_RS11010 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase GE198_RS11015 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase GE198_RS11020 ENOG4105H6Q decarboxylase GE198_RS11025 ENOG4105CMG Carbohydrate kinase GE198_RS11030 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit GE198_RS11035 ENOG4105CG6 trap dicarboxylate transporter dctm subunit GE198_RS11040 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter GE198_RS11045 ENOG4108M5W GE198_RS11050 ENOG4108R66 Conserved Protein GE198_RS11060 ENOG4105J4Q Transcriptional regulator GE198_RS11065 ENOG4108XIB electron transport protein ysaA GE198_RS11070 ENOG4105JKW Valine--pyruvate aminotransferase GE198_RS11075 ENOG4107T9C Alpha amylase catalytic region GE198_RS11080 ENOG4108UR8 BAX protein GE198_RS11085 ENOG4105T16 Transcriptional regulator (AraC family) GE198_RS11095 ENOG4105CMG Carbohydrate kinase GE198_RS11100 ENOG410688U Inner membrane protein yiaB GE198_RS11105 ENOG4105MEV Acyl-transferase GE198_RS11125 ENOG4105DQ6 Transposase GE198_RS11155 ENOG4105MVF Transcriptional regulator GE198_RS11160 ENOG4106JH6 (LipO)protein GE198_RS11170 ENOG4108ZG0 Ompa motb domain protein GE198_RS11175 ENOG4107QY8 reductase GE198_RS11180 ENOG4105HNP -acetyltransferase GE198_RS11185 ENOG4108R3E Dna-3-methyladenine glycosylase i GE198_RS11190 ENOG4105EAX Putative lipase GE198_RS11195 ENOG4105DIJ Phosphoethanolamine transferase GE198_RS11215 ENOG4105CQ4 Transcriptional regulator GE198_RS11230 ENOG4105DEF Extracellular solute-binding protein, family 5 GE198_RS11235 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GE198_RS11240 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GE198_RS11245 ENOG4105C3U ABC transporter GE198_RS11250 ENOG4108JQ7 (ABC) transporter GE198_RS11255 ENOG4105C44 Serine transporter GE198_RS11270 ENOG4105D1V cellulose synthase operon protein YhjU GE198_RS11275 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT GE198_RS11285 ENOG410661M cytoplasmic protein GE198_RS11290 ENOG4105UTS cellulose synthase operon protein YhjQ GE198_RS11295 ENOG4107QZ7 Cellulose synthase catalytic subunit GE198_RS11300 ENOG4107EEX Cellulose synthase regulator protein GE198_RS11305 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) GE198_RS11310 ENOG4105EJG cellulose synthase GE198_RS11315 ENOG4105BZU Histidine kinase GE198_RS11325 ENOG4105CS0 peptidase GE198_RS11330 ENOG4107SS6 2-dehydro-3-deoxygluconokinase GE198_RS11335 ENOG4105CMB EAL domain-containing protein GE198_RS11340 ENOG41066T0 asmA family GE198_RS11345 ENOG4105CSH Transporter GE198_RS11350 ENOG4107H3J ribonuclease GE198_RS11355 ENOG4105CBN LysR family transcriptional regulator GE198_RS11360 ENOG4106S2D Transcriptional regulator GE198_RS11380 ENOG4105FDP GntR family transcriptional regulator GE198_RS11385 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine GE198_RS11390 ENOG4108KPW sugar kinase GE198_RS11395 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GE198_RS11405 ENOG4105DC8 reductase GE198_RS11410 ENOG4105D6S protein involved in catabolism of external DNA GE198_RS11415 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase GE198_RS11420 ENOG4105DGW oligopeptidase A GE198_RS11430 ENOG4105DUX Transporter GE198_RS11435 ENOG4108M6U Universal stress protein A GE198_RS11445 ENOG4105CJ3 phosphate transporter GE198_RS11450 ENOG4105CBX hi0933 family GE198_RS11455 ENOG4105D0S secretion protein (HlyD GE198_RS11460 ENOG4105CJ1 ABC, transporter GE198_RS11465 ENOG4105CMI transporter GE198_RS11475 ENOG4107YAK holo-(acyl carrier protein) synthase 2 GE198_RS11480 ENOG4105DSF transport protein GE198_RS11490 ENOG4108W1V Lipoprotein GE198_RS11495 ENOG4105EX9 Membrane GE198_RS11505 ENOG4105C8Q Methyl-accepting chemotaxis GE198_RS11515 ENOG4107FS9 Membrane GE198_RS11525 ENOG4105MG3 Membrane GE198_RS11530 ENOG4106H78 methyltransferase GE198_RS11535 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) GE198_RS11540 ENOG4105CAK Cell division ATP-binding protein ftsE GE198_RS11545 ENOG4105CRP Part of the ABC transporter FtsEX involved in GE198_RS11555 ENOG4105CP9 extracellular ligand-binding receptor GE198_RS11565 ENOG4105U59 -acetyltransferase GE198_RS11570 ENOG4105CP9 extracellular ligand-binding receptor GE198_RS11575 ENOG4105C32 Amino acid ABC transporter (Permease) GE198_RS11580 ENOG4105CF8 branched-chain amino acid ABC transporter, permease GE198_RS11585 ENOG4105C0Z ABC transporter GE198_RS11590 ENOG4108IV0 ABC, transporter GE198_RS11595 ENOG41060M8 Pfam:PhdYeFM GE198_RS11605 ENOG4105BZ7 extracellular solute-binding protein family 1 GE198_RS11610 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component GE198_RS11625 ENOG4107T6V glycerophosphoryl diester phosphodiesterase GE198_RS11630 ENOG4105WC8 Conserved Protein GE198_RS11635 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) GE198_RS11640 ENOG41080QX K07048 phosphotriesterase-related protein GE198_RS11655 ENOG4108RVA ribokinase GE198_RS11660 ENOG4105WCN acetyltransferase GE198_RS11665 ENOG4105D9R oxidoreductase GE198_RS11670 ENOG4105C2I pirin domain protein GE198_RS11675 ENOG4105DIQ Transcriptional regulator GE198_RS11680 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family GE198_RS11685 ENOG4105C6Z Gluconate GE198_RS11695 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GE198_RS11720 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) GE198_RS11725 ENOG4107HP6 Transcriptional regulator GE198_RS11730 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) GE198_RS11735 ENOG4105C01 Dihydroxy-acid dehydratase GE198_RS11745 ENOG4105DCT glycerol dehydrogenase GE198_RS11760 ENOG4105C6V Glycerol-3-phosphate dehydrogenase GE198_RS11775 ENOG4105E98 transcriptional regulator DeoR family GE198_RS11785 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) GE198_RS11790 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) GE198_RS11795 ENOG4105C6Z Gluconate GE198_RS11805 ENOG4105MJ2 Competence protein GE198_RS11815 ENOG4105DNE Transposase GE198_RS11825 ENOG4105CE1 Ferrous iron transport protein b GE198_RS11830 ENOG4105XFK Ferrous iron transport protein A GE198_RS11835 ENOG4105BZM domain protein GE198_RS11840 ENOG4108RRZ Transcription elongation factor GreB GE198_RS11850 ENOG4105E0F Histidine kinase GE198_RS11860 ENOG4108MAJ Membrane GE198_RS11865 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) GE198_RS11870 ENOG4105VEJ Heat shock protein GE198_RS11875 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 GE198_RS11885 ENOG4107RK2 ADP-ribose diphosphatase NudE GE198_RS11890 ENOG4108JQC penicillin-binding protein 1A GE198_RS11895 ENOG4108U1Q Pilus assembly protein GE198_RS11900 ENOG41065NF Fimbrial assembly family protein GE198_RS11905 ENOG4105XPX DNA utilization protein HofO GE198_RS11910 ENOG4105ITY Required for the use of extracellular DNA as a nutrient GE198_RS11915 ENOG4105E4G Type IV pilus GE198_RS11930 ENOG4105EGB membrane protein DamX GE198_RS11935 ENOG4105DFE Dna adenine methylase GE198_RS11940 ENOG4105DJV ribulose-phosphate 3-epimerase GE198_RS11950 ENOG4105C31 Tryptophanyl-tRNA synthetase GE198_RS11955 ENOG4105VYH GE198_RS11960 ENOG4107EF2 surface-exposed virulence protein GE198_RS11970 ENOG4107V9H nitrite transporter GE198_RS11975 ENOG4105WZK nitrite reductase NADPH small subunit GE198_RS11980 ENOG4107QZF nitrite reductase NADPH large subunit GE198_RS11990 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) GE198_RS11995 ENOG4106195 uncharacterized protein yhfG GE198_RS12000 ENOG4105MZU cell filamentation protein GE198_RS12005 ENOG4105DDQ anthranilate synthase GE198_RS12010 ENOG4105C8Y Acetylornithine aminotransferase GE198_RS12015 ENOG410613R integral membrane protein, YccS YhfK family GE198_RS12020 ENOG4107RYR Transcriptional regulator, Crp Fnr family GE198_RS12025 ENOG4108UKZ OsmC family GE198_RS12030 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) GE198_RS12040 ENOG4105DNZ Alpha Beta Hydrolase GE198_RS12045 ENOG4105N0V mono-oxygenase ydhR GE198_RS12050 ENOG4108K70 Transcriptional regulator GE198_RS12055 ENOG4105C5H ABC transporter GE198_RS12070 ENOG4105VKU nucleicacid-binding protein GE198_RS12075 ENOG4108YZY peptidylprolyl cis-trans isomerase GE198_RS12080 ENOG4105VRX Protein slyX homolog GE198_RS12085 ENOG4108V1T peptidylprolyl cis-trans isomerase GE198_RS12090 ENOG4105WWK YheO domain protein GE198_RS12125 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) GE198_RS12130 ENOG4105W53 bacterioferritin-associated ferredoxin GE198_RS12135 ENOG4108UQY Iron-storage protein GE198_RS12140 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) GE198_RS12170 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) GE198_RS12190 ENOG41083MP 50s ribosomal protein l29 GE198_RS12195 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal GE198_RS12205 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) GE198_RS12230 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) GE198_RS12240 ENOG4105VPB 50S ribosomal protein L30 GE198_RS12250 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) GE198_RS12255 ENOG41067V7 50S ribosomal protein L36 GE198_RS12270 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) GE198_RS12285 ENOG4105VTS DnaJ-like, subfamily C GE198_RS12290 ENOG4105W1Y Transcriptional regulator GE198_RS12295 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system GE198_RS12300 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) GE198_RS12305 ENOG4105C1A potassium transporter peripheral membrane GE198_RS12325 ENOG4105C79 DNA protecting protein DprA GE198_RS12335 ENOG4108WI1 Dna topoisomerase GE198_RS12350 ENOG4105SG3 Protein of unknown function (DUF1488) GE198_RS12355 ENOG4108Z0R Transferase GE198_RS12395 ENOG4105XCM membrane LIPOPROTEIN GE198_RS12400 ENOG4105BZS acriflavin resistance protein GE198_RS12405 ENOG4105C1P efflux transporter, rnd family, mfp subunit GE198_RS12410 ENOG4108XG4 DNA-binding transcriptional regulator GE198_RS12415 ENOG4105BZU Histidine kinase GE198_RS12420 ENOG41061ME transport protein GE198_RS12425 ENOG4105CEC DNA methylase N-4 N-6 GE198_RS12435 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GE198_RS12445 ENOG4108IA2 Sodium pantothenate symporter GE198_RS12450 ENOG4105RG0 Membrane GE198_RS12455 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase GE198_RS12460 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein GE198_RS12475 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family GE198_RS12480 ENOG41062P1 Diguanylate cyclase phosphodiesterase GE198_RS12490 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) GE198_RS12495 ENOG4105VQ7 Rod shape-determining protein MreD GE198_RS12500 ENOG4108Z03 MAF-like protein GE198_RS12505 ENOG4105C03 ribonuclease GE198_RS12510 ENOG4105QD6 exported protein GE198_RS12515 ENOG4105D1U peptidase U62 modulator of DNA gyrase GE198_RS12520 ENOG4105CR8 Transcriptional regulator GE198_RS12525 ENOG4105ZQC membrane protein AaeX GE198_RS12540 ENOG4105UNR (Barnase) inhibitor GE198_RS12545 ENOG4105RID UPF0379 protein yhcN GE198_RS12550 ENOG4105RID UPF0379 protein yhcN GE198_RS12575 ENOG4105C8P )-transporter GE198_RS12580 ENOG4106DSS Tartrate dehydratase subunit alpha GE198_RS12585 ENOG4107GFK fumarate GE198_RS12595 ENOG4107QSA Oxaloacetate decarboxylase GE198_RS12600 ENOG4105D9Q decarboxylase (Beta subunit) GE198_RS12615 ENOG4105C0H protease GE198_RS12620 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III GE198_RS12625 ENOG4105D6Z AFG1 family ATPase GE198_RS12645 ENOG4107MKT Stringent starvation protein a GE198_RS12650 ENOG4105KB2 stringent starvation protein b GE198_RS12680 ENOG4108R66 Conserved Protein GE198_RS12685 ENOG4105DZC cytosine deaminase GE198_RS12690 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin GE198_RS12695 ENOG4105DFS Conserved Protein GE198_RS12700 ENOG4105BZ8 glutamate synthase GE198_RS12705 ENOG4105CBC glutamate synthase GE198_RS12710 ENOG4105N5T Radical SAM Protein GE198_RS12715 ENOG4105BZU Histidine kinase GE198_RS12720 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain GE198_RS12725 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase GE198_RS12730 ENOG4108NIH transferase activity, transferring phosphorus-containing groups GE198_RS12735 ENOG41080Z8 PHOSPHOCARRIER protein GE198_RS12745 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN GE198_RS12750 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA GE198_RS12755 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GE198_RS12760 ENOG4108IUZ ABC transporter GE198_RS12765 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA GE198_RS12770 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) GE198_RS12775 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase GE198_RS12780 ENOG4105C2X Arabinose 5-phosphate isomerase GE198_RS12785 ENOG4105FEU K -dependent Na -Ca exchanger GE198_RS12790 ENOG4105DHJ ABC, transporter GE198_RS12795 ENOG4105CY3 ABC transporter, permease GE198_RS12800 ENOG4107PE3 Mammalian cell entry related domain protein GE198_RS12805 ENOG4105E3I toluene tolerance GE198_RS12810 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane GE198_RS12815 ENOG4105VFK BolA family GE198_RS12825 ENOG4105HVQ Regulatory factor of maltose metabolism GE198_RS12830 ENOG4105EAH synthase GE198_RS12840 ENOG4105K46 50S ribosomal protein l27 GE198_RS12845 ENOG4105QYV Membrane GE198_RS12855 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase GE198_RS12860 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) GE198_RS12865 ENOG4105HBR Rna-binding protein GE198_RS12875 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GE198_RS12880 ENOG4105EEI dihydropteroate synthase GE198_RS12890 ENOG4105NTZ Preprotein translocase subunit SecG GE198_RS12915 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) GE198_RS12920 ENOG4105CHV Transcription elongation factor NusA GE198_RS12960 ENOG4105C1J atp-dependent rna helicase GE198_RS12965 ENOG4105CIC tryptophan-specific transport protein GE198_RS12970 ENOG4105DEN Luciferase family GE198_RS12990 ENOG4108YYD acetyltransferase GE198_RS13005 ENOG4107R7Y intracellular protease Pfpi family GE198_RS13010 ENOG4105K4T epimerase GE198_RS13015 ENOG4105W4M Transport-associated protein GE198_RS13035 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) GE198_RS13045 ENOG4107WTH Galactitol-1-phosphate dehydrogenase GE198_RS13050 ENOG4105DT3 PTS system, galactitol-specific IIc component GE198_RS13055 ENOG41090UW PTS System GE198_RS13060 ENOG41082GB PTS system galactitol-specific transporter subunit IIA GE198_RS13075 ENOG4105CTX dehydratase GE198_RS13085 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GE198_RS13090 ENOG4105BZW Glycerate kinase GE198_RS13100 ENOG410811B TRANSCRIPTIONal GE198_RS13105 ENOG4105C7B Threonine dehydratase GE198_RS13120 ENOG4105C6N Formate acetyltransferase GE198_RS13125 ENOG4105EJQ L-serine dehydratase GE198_RS13130 ENOG4105C44 Serine transporter GE198_RS13140 ENOG4106D80 Uncharacterized protein YhaL GE198_RS13145 ENOG4108CNN domain protein GE198_RS13150 ENOG4105CWB LysR family transcriptional Regulator GE198_RS13155 ENOG4105KAF membrAne GE198_RS13160 ENOG4105CHF Glutathione S-transferase GE198_RS13165 ENOG4108VBZ doxx family GE198_RS13170 ENOG4105YJD GE198_RS13175 ENOG41090KG Inner membrane protein YqjE GE198_RS13180 ENOG4105NE1 Conserved Protein GE198_RS13185 ENOG4105WAY exported protein GE198_RS13195 ENOG4106W5V Membrane GE198_RS13205 ENOG4105DU1 integral membrane protein, terc GE198_RS13210 ENOG4105EE0 oxidoreductase GE198_RS13215 ENOG4108UB4 uncharacterized protein ygjQ GE198_RS13220 ENOG4108VKG metal-dependent hydrolase GE198_RS13230 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GE198_RS13240 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor GE198_RS13245 ENOG4105C8Q Methyl-accepting chemotaxis GE198_RS13250 ENOG4105NTW Transcriptional regulator GE198_RS13255 ENOG4105Q26 Siderophore-interacting protein GE198_RS13265 ENOG4108VCA G U mismatch-specific DNA glycosylase GE198_RS13270 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GE198_RS13275 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) GE198_RS13305 ENOG4107ZVW dihydroneopterin aldolase GE198_RS13320 ENOG4106MWK domain protein GE198_RS13325 ENOG4105I7R Adenylate cyclase GE198_RS13345 ENOG4107S78 Band 7 protein GE198_RS13350 ENOG4105PV3 Inner membrane protein yqiJ GE198_RS13360 ENOG4105W0Z cytoplasmic protein GE198_RS13370 ENOG4108PSN Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity) GE198_RS13380 ENOG4108MR7 Arylsulfotransferase GE198_RS13390 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b GE198_RS13395 ENOG4106032 Glutathionylspermidine synthase GE198_RS13400 ENOG4105F1G UPF0441 protein GE198_RS13410 ENOG41087AY ADP-Ribose pyrophosphatase GE198_RS13415 ENOG4108SX3 cytoplasmic protein GE198_RS13420 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) GE198_RS13425 ENOG4105IPS esterase GE198_RS13430 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GE198_RS13435 ENOG4105VRH Antibiotic biosynthesis monooxygenase GE198_RS13440 ENOG4105NF4 modulator of drug activity GE198_RS13445 ENOG4105DHQ Histidine kinase GE198_RS13450 ENOG4105XJC Two component transcriptional regulator (Winged helix family GE198_RS13455 ENOG4105H4F exported protein GE198_RS13460 ENOG4105F4I Transcriptional regulator GE198_RS13465 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GE198_RS13470 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase GE198_RS13475 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) GE198_RS13480 ENOG4105CG6 trap dicarboxylate transporter dctm subunit GE198_RS13490 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit GE198_RS13495 ENOG4105CCT upf0313 protein GE198_RS13510 ENOG4107QPK )-transporter GE198_RS13515 ENOG4105CV8 reductase GE198_RS13520 ENOG4108I6A alcohol dehydrogenase GE198_RS13525 ENOG4105CF7 AraC family transcriptional regulator GE198_RS13530 ENOG4108K81 inner membrane protein YghB GE198_RS13535 ENOG4105C28 cystathionine GE198_RS13540 ENOG4105CWK Biopolymer transport protein, ExbB GE198_RS13545 ENOG4108ZZF transport protein (ExbD) GE198_RS13550 ENOG4105CYX Short-chain dehydrogenase reductase Sdr GE198_RS13575 ENOG4105C8Q Methyl-accepting chemotaxis GE198_RS13580 ENOG410900S Protein of unknown function (DUF2623) GE198_RS13585 ENOG4105E3S small subunit GE198_RS13590 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GE198_RS13595 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit GE198_RS13600 ENOG4105DPX Hydrogenase, large subunit GE198_RS13605 ENOG4108USZ hydrogenase GE198_RS13610 ENOG4108WGS hydrogenase 2-specific chaperone GE198_RS13615 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) GE198_RS13620 ENOG41082MF Hydrogenase assembly chaperone hypC hupF GE198_RS13625 ENOG4105S10 periplasmic binding protein GE198_RS13630 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein GE198_RS13635 ENOG4105CYM Glutathione S-transferase GE198_RS13640 ENOG4106032 Glutathionylspermidine synthase GE198_RS13655 ENOG4105DEI Mannitol dehydrogenase GE198_RS13665 ENOG4105DPW Major facilitator superfamily MFS_1 GE198_RS13690 ENOG4105C26 Dehydrogenase GE198_RS13695 ENOG4105CJP fad dependent oxidoreductase GE198_RS13705 ENOG4105CUB amino acid GE198_RS13715 ENOG4108UAJ Transcriptional regulator GE198_RS13725 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) GE198_RS13735 ENOG4105CI0 Citrate lyase GE198_RS13740 ENOG4105DJG MaoC domain protein dehydratase GE198_RS13745 ENOG4105CYC Transferase GE198_RS13750 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase GE198_RS13760 ENOG4108UQV Membrane GE198_RS13765 ENOG4105CXN decarboxylase GE198_RS13770 ENOG4105EAA nucleoside GE198_RS13780 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) GE198_RS13785 ENOG4105CEN a g-specific adenine glycosylase GE198_RS13795 ENOG41090ED Protein with unknown function (DUF469) GE198_RS13800 ENOG4105K33 Periplasmic Protein GE198_RS13805 ENOG4105HDK L-asparaginase GE198_RS13810 ENOG4106MH3 alpha helix chain GE198_RS13815 ENOG4105CSA Coproporphyrinogen iii oxidase GE198_RS13830 ENOG4108VIA integral membrane protein GE198_RS13835 ENOG4105DFA alanine racemase domain protein GE198_RS13840 ENOG4105CZX twitching motility protein GE198_RS13860 ENOG4105D7Z glutathione synthase GE198_RS13865 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) GE198_RS13870 ENOG4105RWS endonuclease I GE198_RS13880 ENOG4107QNK )-transporter GE198_RS13905 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) GE198_RS13915 ENOG4107YCY Transcriptional regulator GE198_RS13925 ENOG4105DEI Mannitol dehydrogenase GE198_RS13930 ENOG4105CPQ Dehydrogenase GE198_RS13935 ENOG4105DG4 malate L-lactate dehydrogenase GE198_RS13940 ENOG4108R66 Conserved Protein GE198_RS13945 ENOG4108MXF Alpha Beta Hydrolase GE198_RS13955 ENOG4108K0D peptidase, M48 GE198_RS13960 ENOG4105CV1 Transketolase (EC 2.2.1.1) GE198_RS13965 ENOG4108JJB ABC transporter GE198_RS13970 ENOG4108JJB ABC transporter GE198_RS13995 ENOG4105BZA Phosphoglycerate kinase GE198_RS14000 ENOG4105D2N Aldolase GE198_RS14005 ENOG4105D64 Mechanosensitive ion channel GE198_RS14015 ENOG4105MPN Membrane GE198_RS14030 ENOG4108JQ1 Dehydrogenase GE198_RS14035 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase GE198_RS14055 ENOG4107RAQ aminopeptidase GE198_RS14060 ENOG4105D0A hydroxylase GE198_RS14065 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family GE198_RS14090 ENOG4105CS2 ec 3.2.1.21 GE198_RS14100 ENOG4108UT2 hemolysin iii GE198_RS14115 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB GE198_RS14120 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) GE198_RS14125 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GE198_RS14130 ENOG4105T95 Thiol disulfide interChange protein GE198_RS14135 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) GE198_RS14155 ENOG4108K5P (LipO)protein GE198_RS14170 ENOG4105VGJ Virulence-associated protein GE198_RS14175 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A GE198_RS14180 ENOG4108T1M outer membrane protein x GE198_RS14200 ENOG4106P2F Pfam:Pili_assembly_C GE198_RS14230 ENOG4108MHD transport protein GE198_RS14240 ENOG4105C5Q Transcriptional regulator GE198_RS14245 ENOG4105CHU acetyl-coa acetyltransferase GE198_RS14255 ENOG4105CHR reductase GE198_RS14260 ENOG4107QNK )-transporter GE198_RS14270 ENOG4105RQF LysR family Transcriptional regulator GE198_RS14280 ENOG4105DDV Transcriptional regulator (LacI family GE198_RS14300 ENOG4105CPC Aldo Keto reductase GE198_RS14305 ENOG4105SUV lipoprotein YgdR GE198_RS14310 ENOG4105EE5 Membrane protein terC GE198_RS14325 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase GE198_RS14340 ENOG4105IPU prepilin peptidase dependent protein A GE198_RS14345 ENOG4105JCS prepilin peptidase dependent protein GE198_RS14350 ENOG4105SEN Protein of unknown function (DUF2509) GE198_RS14355 ENOG4105RVB Prepilin peptidase dependent protein c GE198_RS14360 ENOG4105DSY exodeoxyribonuclease V, gamma GE198_RS14365 ENOG4107QXK peptidase GE198_RS14370 ENOG4107QKA exodeoxyribonuclease V beta GE198_RS14375 ENOG4107QYX exodeoxyribonuclease v alpha GE198_RS14380 ENOG4108EKC n-acetylglutamate synthase GE198_RS14385 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GE198_RS14400 ENOG4105CA3 membrane-bound lytic murein transglycosylase GE198_RS14405 ENOG4105CUZ uba thif-type nad fad binding protein GE198_RS14410 ENOG4105FR1 rard protein GE198_RS14415 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) GE198_RS14420 ENOG4105C9B Cysteine desulfurase GE198_RS14425 ENOG4105M5B (LipO)protein GE198_RS14430 ENOG4105ETT transcriptional Regulator, LysR family GE198_RS14435 ENOG4105M08 Membrane GE198_RS14445 ENOG4107EDW L-fucose operon activator GE198_RS14455 ENOG4105CMG Carbohydrate kinase GE198_RS14465 ENOG4105EDR glucose galactose transporter GE198_RS14470 ENOG4107W7X Aldolase GE198_RS14475 ENOG4105C0A alcohol dehydrogenase GE198_RS14485 ENOG4105EJQ L-serine dehydratase GE198_RS14490 ENOG4105C44 Serine transporter GE198_RS14495 ENOG4105EWT decarboxylase family GE198_RS14515 ENOG4105WP7 tRNA pseudouridine synthase C GE198_RS14520 ENOG4105DR9 pseudouridine synthase GE198_RS14525 ENOG4105QDK Flavodoxin GE198_RS14530 ENOG4105DJB Major Facilitator Superfamily GE198_RS14535 ENOG4105EQX glucarate dehydratase GE198_RS14540 ENOG4105EQX glucarate dehydratase GE198_RS14545 ENOG4105BZW Glycerate kinase GE198_RS14550 ENOG4105BZU Histidine kinase GE198_RS14555 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) GE198_RS14560 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) GE198_RS14565 ENOG4105X54 addiction module antidote protein GE198_RS14575 ENOG4105DXN mazG family GE198_RS14585 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) GE198_RS14590 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) GE198_RS14595 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) GE198_RS14600 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase GE198_RS14610 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) GE198_RS14615 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) GE198_RS14625 ENOG4105DTT CRISPR-associated helicase, cas3 GE198_RS14630 ENOG4105CYR Crispr-associated protein, cse1 family GE198_RS14640 ENOG41060M0 Crispr-associated protein, cse4 family GE198_RS14645 ENOG4108VWQ crispr-associated protein GE198_RS14655 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) GE198_RS14660 ENOG4105PWE CRISPR-associated protein cas2 GE198_RS14665 ENOG4108MXK alkaline phosphatase isozyme conversion GE198_RS14685 ENOG4105N0Z inner membrane protein ygbE GE198_RS14695 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) GE198_RS14700 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) GE198_RS14720 ENOG4108K5P (LipO)protein GE198_RS14730 ENOG4105KZM cytoplasmic protein GE198_RS14735 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) GE198_RS14740 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase GE198_RS14750 ENOG4105MVE transcriptional regulator GE198_RS14760 ENOG4105G63 Type III effector Hrp-dependent GE198_RS14770 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) GE198_RS14775 ENOG4105EXW epimerase dehydratase GE198_RS14780 ENOG4105C6Z Gluconate GE198_RS14785 ENOG4105JQN Transcriptional regulator GE198_RS14790 ENOG4105C0R drug resistance transporter emrb qaca subfamily GE198_RS14825 ENOG4105MEW serine threonine protein phosphatase GE198_RS14855 ENOG41090HZ type iii secretion GE198_RS14865 ENOG4108N8R Invasion protein GE198_RS14870 ENOG4108HR8 type iii secretion GE198_RS14875 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone GE198_RS14880 ENOG4108JIR Flagellum-specific ATP synthase GE198_RS14885 ENOG41077MC Secretory protein (Associated with virulence) GE198_RS14890 ENOG41078G4 surface presentation of GE198_RS14895 ENOG4105T85 surface presentation of antigens protein GE198_RS14900 ENOG41075IY surface presentation of antigens protein SpaP GE198_RS14905 ENOG4105U07 type iii secretion GE198_RS14910 ENOG4108TN6 type iii secretion GE198_RS14915 ENOG4108M6W surface presentation of antigens protein SpaS GE198_RS14925 ENOG4106H1J Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE GE198_RS14935 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC GE198_RS14945 ENOG41079WB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GE198_RS14960 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear GE198_RS14970 ENOG4108YAB Invasion protein GE198_RS14980 ENOG4108RC9 Type III secretion system protein GE198_RS14985 ENOG4105Y7Q type iii secretion GE198_RS14990 ENOG4106BTR GE198_RS14995 ENOG4108RBT type iii secretion GE198_RS15030 ENOG4105CC5 ABC transporter GE198_RS15035 ENOG4105CC5 ABC transporter GE198_RS15040 ENOG4105DIK (ABC) transporter GE198_RS15050 ENOG4105VXR cytoplasmic protein GE198_RS15060 ENOG4105C45 hydrogenase expression formation protein (HypE) GE198_RS15065 ENOG4105CQS hydrogenase expression formation protein HypD GE198_RS15070 ENOG41083WG hydrogenase assembly chaperone GE198_RS15075 ENOG4107RSS Hydrogenase accessory protein HypB GE198_RS15080 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) GE198_RS15085 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA GE198_RS15090 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) GE198_RS15095 ENOG4107R30 NADH dehydrogenase GE198_RS15100 ENOG4107TDF Formate hydrogenlyase subunit 4 GE198_RS15105 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GE198_RS15110 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit GE198_RS15115 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit GE198_RS15120 ENOG4105I6X formate hydrogenlyase maturation GE198_RS15125 ENOG4108MG9 hydrogenase 3 maturation protease GE198_RS15135 ENOG4108RC0 Electron transport protein GE198_RS15140 ENOG4105C8H hydrogenase maturation protein Hypf GE198_RS15160 ENOG4105C2X Arabinose 5-phosphate isomerase GE198_RS15165 ENOG410804X Transcriptional regulator GE198_RS15170 ENOG4105J92 DNA-binding transcriptional activator GutM GE198_RS15175 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase GE198_RS15180 ENOG4105VI0 Pts system, glucitol sorbitol-specific GE198_RS15185 ENOG4105DZY Pts system, glucitol sorbitol-specific GE198_RS15190 ENOG410787A Pts system, glucitol sorbitol-specific GE198_RS15195 ENOG4105CVE Lytic murein transglycosylase GE198_RS15200 ENOG4107TH8 cina domain protein GE198_RS15215 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) GE198_RS15220 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) GE198_RS15250 ENOG4107VXZ Hydrolase GE198_RS15255 ENOG4105W39 Membrane GE198_RS15275 ENOG4105C0R drug resistance transporter emrb qaca subfamily GE198_RS15280 ENOG4105CW7 secretion protein, HlyD family GE198_RS15285 ENOG4105NTK Transcriptional repressor Mpra GE198_RS15295 ENOG4105GIJ Glycine betaine GE198_RS15300 ENOG4108HQS Glycine betaine GE198_RS15305 ENOG4108IJ7 Glycine betaine GE198_RS15310 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GE198_RS15315 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GE198_RS15325 ENOG4105WAZ (Glutaredoxin-like protein) NrdH GE198_RS15330 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) GE198_RS15340 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) GE198_RS15345 ENOG4108WMJ Protein of unknown function (DUF2002) GE198_RS15350 ENOG4108RNS Exports L-alanine (By similarity) GE198_RS15355 ENOG4108X73 DNA- binding protein GE198_RS15365 ENOG4108V62 Rhodanese domain protein GE198_RS15370 ENOG41080HT Transcriptional regulator, arsr family GE198_RS15375 ENOG4105VPI YqaE family transport protein GE198_RS15380 ENOG4109066 lysm domain bon superfamily protein GE198_RS15385 ENOG4108PVQ transcriptional regulator GE198_RS15390 ENOG4105C85 amino acid GE198_RS15395 ENOG4108JPW Aminotransferase GE198_RS15400 ENOG4105C26 Dehydrogenase GE198_RS15405 ENOG4105D5U fad dependent oxidoreductase GE198_RS15410 ENOG4105EK3 May be involved in the control of utilization of gamma- aminobutyric acid (By similarity) GE198_RS15435 ENOG4105DHQ Histidine kinase GE198_RS15450 ENOG4108MJ5 VirK protein GE198_RS15455 ENOG4105VRE Pentapeptide repeat protein GE198_RS15465 ENOG4107RNH Outer membrane receptor FepA GE198_RS15470 ENOG4105NIV Esterase GE198_RS15490 ENOG4108C33 Resolvase GE198_RS15495 ENOG4105I03 Flagellin GE198_RS15540 ENOG4105ZTC transcriptional activator, Ogr delta GE198_RS15570 ENOG4105BZ1 (ABC) transporter GE198_RS15590 ENOG4108Z1B Cyclase dehydrase GE198_RS15600 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) GE198_RS15605 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) GE198_RS15625 ENOG4108JU6 CBS domain protein GE198_RS15630 ENOG4106KVJ cytochrome C assembly protein GE198_RS15635 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY GE198_RS15655 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) GE198_RS15660 ENOG4108KHX Diguanylate cyclase GE198_RS15665 ENOG4108WS1 GE198_RS15670 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GE198_RS15675 ENOG4105EHE chorismate mutase- prephenate dehydrogenase GE198_RS15685 ENOG4105CQC Prephenate dehydratase GE198_RS15695 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA GE198_RS15700 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane GE198_RS15705 ENOG4105C34 Pseudouridine synthase GE198_RS15710 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase GE198_RS15715 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GE198_RS15745 ENOG4105CSH Transporter GE198_RS15750 ENOG4105T42 (LipO)protein GE198_RS15755 ENOG4105JIM Phosphatidylserine synthase GE198_RS15760 ENOG4105CD5 CoA-binding domain protein GE198_RS15765 ENOG4106IUH DTW domain containing protein GE198_RS15770 ENOG4105K63 Thioredoxin GE198_RS15775 ENOG4105EIB trna rrna methyltransferase GE198_RS15785 ENOG4108VKA Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity) GE198_RS15795 ENOG41090KR LysR family transcriptional Regulator GE198_RS15800 ENOG4105C1J atp-dependent rna helicase GE198_RS15810 ENOG4108IYU L-aspartate oxidase GE198_RS15835 ENOG4105WMJ Positive regulator of sigma E, RseC MucC GE198_RS15845 ENOG4105C3F Signal peptidase i GE198_RS15875 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding GE198_RS15880 ENOG4105DND Transcriptional regulator GE198_RS15890 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) GE198_RS15895 ENOG4106G6Q Transcriptional regulator GE198_RS15910 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB GE198_RS15915 ENOG4108Z6B deaminase GE198_RS15920 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) GE198_RS15930 ENOG4108ETH Formylglycinamide ribotide synthetase GE198_RS15935 ENOG4107WP9 Histidine kinase GE198_RS15940 ENOG4108SKK alpha helix protein GE198_RS15945 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GE198_RS15955 ENOG4105DUX Transporter GE198_RS15960 ENOG4105CXN decarboxylase GE198_RS15965 ENOG4105D5Q Arginine ornithine antiporter GE198_RS15970 ENOG4108M3R transcriptional activator CadC GE198_RS15975 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GE198_RS15985 ENOG4105D8G Major Facilitator superfamily GE198_RS15990 ENOG4108MN2 Stationary phase inducible protein CsiE GE198_RS16000 ENOG4105D7X high-affinity nickel-transporter GE198_RS16005 ENOG410810Y Sulfite reductase GE198_RS16010 ENOG4107SHJ sulfite reductase subunit b GE198_RS16015 ENOG4105D5B Sulfite reductase, subunit A GE198_RS16020 ENOG4107XM9 (LipO)protein GE198_RS16025 ENOG4105ECY inositol monophosphatase GE198_RS16030 ENOG4105CVS RNA methyltransferase TrmH family, group 1 GE198_RS16045 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins GE198_RS16050 ENOG4108Z4V iron-sulfur cluster assembly GE198_RS16065 ENOG4108ZIT Ferredoxin, 2FE-2S GE198_RS16070 ENOG4105WVQ Fe-S assembly protein IscX GE198_RS16080 ENOG4105YYA enhanced serine sensitivity protein SseB GE198_RS16095 ENOG4105KHC sulfurtransferase GE198_RS16100 ENOG4105DN3 alpha-2-macroglobulin domain protein GE198_RS16105 ENOG4108JQB penicillin-binding protein 1C GE198_RS16110 ENOG4107QY8 reductase GE198_RS16115 ENOG4105QAX Iron-sulfur GE198_RS16135 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs GE198_RS16155 ENOG4105N21 Membrane GE198_RS16160 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) GE198_RS16170 ENOG4105VPD cellular component movement GE198_RS16205 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) GE198_RS16230 ENOG41062G3 Protein of unknown function (DUF2633) GE198_RS16240 ENOG4105BZU Histidine kinase GE198_RS16245 ENOG4105C9X ppx gppa phosphatase GE198_RS16250 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) GE198_RS16255 ENOG4108V3E phosphoribosylglycinamide formyltransferase GE198_RS16265 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) GE198_RS16270 ENOG4105C2W permease GE198_RS16280 ENOG4105K89 arsenate reductase GE198_RS16285 ENOG4105ERG peptidase m48, ste24p GE198_RS16290 ENOG4105C02 permease GE198_RS16295 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR GE198_RS16300 ENOG4107QQ0 gntp family GE198_RS16305 ENOG4105BZW Glycerate kinase GE198_RS16310 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GE198_RS16315 ENOG4105RH4 Glycine cleavage system transcriptional repressor GE198_RS16325 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) GE198_RS16335 ENOG4105CGZ zinc metallopeptidase GE198_RS16340 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) GE198_RS16355 ENOG4105KUZ arsenate reductase GE198_RS16365 ENOG4105BZS acriflavin resistance protein GE198_RS16370 ENOG4105BZU Histidine kinase GE198_RS16375 ENOG4105BZ8 glutamate synthase GE198_RS16380 ENOG4107S1E Beta-lactamase GE198_RS16385 ENOG4107VIJ nudix hydrolase GE198_RS16390 ENOG4108PVD exported protein GE198_RS16400 ENOG4105CV1 Transketolase (EC 2.2.1.1) GE198_RS16410 ENOG4105C6K Malic enzyme GE198_RS16415 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place GE198_RS16420 ENOG4106S4J ethanolamine utilization protein EutP GE198_RS16425 ENOG4105NDK ethanolamine utilization protein GE198_RS16430 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase GE198_RS16435 ENOG4108IJ2 phosphate acetyltransferase GE198_RS16440 ENOG4105KNY Microcompartments protein GE198_RS16445 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml GE198_RS16450 ENOG4108EKI Dehydrogenase GE198_RS16455 ENOG4107YMV ethanolamine utilization protein GE198_RS16460 ENOG4105C0A alcohol dehydrogenase GE198_RS16465 ENOG4105ENY Ethanolamine utilization protein eutH GE198_RS16470 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase GE198_RS16475 ENOG4105CPD ethanolamine ammonia-lyase GE198_RS16485 ENOG4106D67 ethanolamine utilization protein GE198_RS16490 ENOG4108X49 Ethanolamine utilization protein EutK GE198_RS16495 ENOG4108K3Z AraC family transcriptional regulator GE198_RS16500 ENOG4107H8F GE198_RS16515 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase GE198_RS16520 ENOG4108R6G acetyltransferase GE198_RS16525 ENOG4105QZU Inner membrane protein YfeZ GE198_RS16530 ENOG4105E7K (LipO)protein GE198_RS16535 ENOG4105EZR dyp-type peroxidase family protein GE198_RS16540 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr GE198_RS16545 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein GE198_RS16550 ENOG4108I5D sulfate abc transporter GE198_RS16555 ENOG4105ECW sulfate abc transporter GE198_RS16560 ENOG4108IJ6 ABC transporter GE198_RS16565 ENOG4105C6T cysteine synthase GE198_RS16575 ENOG4105M0Y GE198_RS16580 ENOG41089BK Glutamine amido-transferase GE198_RS16585 ENOG4105CSW GntR family transcriptional regulator GE198_RS16590 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) GE198_RS16600 ENOG4105C5Y PTS System GE198_RS16605 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GE198_RS16615 ENOG4105C6T cysteine synthase GE198_RS16620 ENOG4105EXN Sulfate transport protein CysZ GE198_RS16635 ENOG4105VRT cytoplasmic protein GE198_RS16640 ENOG4105DHU Bile acid GE198_RS16645 ENOG4108M0I Transcriptional regulator GE198_RS16650 ENOG4108NFH Sugar hydrolase GE198_RS16655 ENOG4105EAA nucleoside GE198_RS16665 ENOG4105CN8 Transcriptional regulator GE198_RS16695 ENOG4105GXM Putative transcription regulator (DUF1323) GE198_RS16700 ENOG4105HZG regulatoR GE198_RS16715 ENOG4108KMM Diguanylate cyclase GE198_RS16720 ENOG4105D9N nucleoside GE198_RS16730 ENOG4109076 Conserved Protein GE198_RS16735 ENOG4105CPC Aldo Keto reductase GE198_RS16740 ENOG4107RA9 decarboxylase GE198_RS16755 ENOG4105CHM Aminotransferase GE198_RS16765 ENOG4105D1S lipid A biosynthesis GE198_RS16770 ENOG4105W9M Membrane GE198_RS16775 ENOG4105CXY transporter GE198_RS16780 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC GE198_RS16790 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta GE198_RS16795 ENOG4108NC2 Outer membrane protease GE198_RS16805 ENOG4105S64 Formate nitrite transporter GE198_RS16810 ENOG410903C (LipO)protein GE198_RS16815 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation GE198_RS16820 ENOG4105KZW UPF0381 protein GE198_RS16835 ENOG4108BY2 phosphohistidine phosphatase GE198_RS16845 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) GE198_RS16860 ENOG4105EJ9 Membrane GE198_RS16865 ENOG4108BPE -transporting atpase GE198_RS16870 ENOG4105MH2 YfcL protein GE198_RS16875 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) GE198_RS16880 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GE198_RS16900 ENOG4105R8V Transcriptional regulator GE198_RS16915 ENOG4106WZ1 flagella biosynthesis regulator GE198_RS16925 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GE198_RS16935 ENOG4105DQR SNARE associated Golgi GE198_RS16945 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase GE198_RS16950 ENOG4108S3P Sporulation domain protein GE198_RS16955 ENOG4105E96 Colicin v production protein GE198_RS16960 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase GE198_RS16965 ENOG4108JUB Transcriptional regulator GE198_RS16975 ENOG4105E5D amino acid GE198_RS16980 ENOG4106M28 alanine racemase domain protein GE198_RS16990 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase GE198_RS16995 ENOG4105E89 ABC transporter GE198_RS17000 ENOG4105E89 ABC transporter GE198_RS17005 ENOG4105DSP amino acid AbC transporter GE198_RS17010 ENOG4106YG3 ABC transporter GE198_RS17015 ENOG4108JEH abc transporter atp-binding protein GE198_RS17020 ENOG4105ECP epimerase GE198_RS17025 ENOG4105CYM Glutathione S-transferase GE198_RS17030 ENOG4108SHQ Glutathione S-transferase GE198_RS17035 ENOG4108RE9 Phosphodiesterase GE198_RS17040 ENOG4105PTV Nudix Hydrolase GE198_RS17045 ENOG4105K2J Transcriptional regulator GE198_RS17050 ENOG4106ETB IIa component GE198_RS17060 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC GE198_RS17065 ENOG4108HHA Transketolase GE198_RS17070 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) GE198_RS17075 ENOG4105CSX c4-dicarboxylate anaerobic carrier GE198_RS17080 ENOG4105C6K Malic enzyme GE198_RS17085 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) GE198_RS17100 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 GE198_RS17105 ENOG4107QWE )-transporter GE198_RS17115 ENOG4105CHM Aminotransferase GE198_RS17120 ENOG4107NQ8 LysR family Transcriptional regulator GE198_RS17130 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain GE198_RS17135 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GE198_RS17145 ENOG4105GKE subunit e GE198_RS17150 ENOG4107QIZ NADH dehydrogenase GE198_RS17155 ENOG4108IEH NADH dehydrogenase subunit g GE198_RS17170 ENOG4107UFS subunit j GE198_RS17180 ENOG4105D65 subunit l GE198_RS17185 ENOG4105C8S subunit m GE198_RS17205 ENOG4107YB6 acetyltransferase, (GNAT) family GE198_RS17210 ENOG4105TNS Conserved Protein GE198_RS17215 ENOG4105E4F Isochorismate synthase GE198_RS17230 ENOG4108IPT Naphthoate synthase GE198_RS17235 ENOG4105DNI Converts SHCHC to OSB (By similarity) GE198_RS17240 ENOG4105CEY Amp-dependent synthetase and ligase GE198_RS17245 ENOG4106GZG polymyxin resistance protein B GE198_RS17295 ENOG4108UII YfaZ family GE198_RS17300 ENOG4108EWA cinA-like protein GE198_RS17305 ENOG4107258 Transcriptional regulator GE198_RS17315 ENOG4105CSP Major Facilitator Superfamily GE198_RS17335 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GE198_RS17345 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A GE198_RS17350 ENOG4105CXY transporter GE198_RS17355 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase GE198_RS17360 ENOG4105GZI Transcriptional regulator GE198_RS17365 ENOG4105CZM Major Facilitator GE198_RS17370 ENOG4105XPH Ferredoxin GE198_RS17375 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GE198_RS17380 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GE198_RS17400 ENOG4105CXK mandelate racemase muconate lactonizing GE198_RS17405 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GE198_RS17410 ENOG4105BZU Histidine kinase GE198_RS17415 ENOG41068CG regulatoR GE198_RS17420 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC GE198_RS17425 ENOG4105FCK Membrane GE198_RS17430 ENOG4105CJ2 (LipO)protein GE198_RS17435 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GE198_RS17440 ENOG4105CF1 Alkylated DNA repair protein GE198_RS17445 ENOG4105IBP Cyclic peptide transporter GE198_RS17455 ENOG4108ZNS ferredoxin-type protein NapF GE198_RS17460 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase GE198_RS17470 ENOG4108BGM Quinol dehydrogenase periplasmic component GE198_RS17475 ENOG4105GXZ Ferredoxin-type protein NapH GE198_RS17480 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) GE198_RS17485 ENOG4105CUW cytochrome C-TYPE protein GE198_RS17495 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) GE198_RS17500 ENOG41060IM Heme exporter protein GE198_RS17505 ENOG4105X3C heme exporter protein GE198_RS17515 ENOG4105DA4 cytochrome c-type biogenesis protein GE198_RS17520 ENOG4107QX9 Thiol disulfide interChange protein GE198_RS17525 ENOG4105KWW Biogenesis protein GE198_RS17530 ENOG4105WH1 Two component transcriptional regulator luxr family GE198_RS17550 ENOG4108X9F tail fiber protein GE198_RS17575 ENOG4105E68 Sulfatase GE198_RS17600 ENOG4105CFI type iii restriction protein res subunit GE198_RS17605 ENOG4105I08 Pseudouridine synthase GE198_RS17610 ENOG4105C2C drug resistance transporter, Bcr CflA GE198_RS17615 ENOG4105HG6 GE198_RS17620 ENOG4108JQ5 ABC transporter GE198_RS17625 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component GE198_RS17630 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component GE198_RS17635 ENOG4105E43 Extracellular solute-binding protein, family 5 GE198_RS17640 ENOG4105CXC rtn protein GE198_RS17645 ENOG4107TT5 NLP P60 protein GE198_RS17650 ENOG41076MN Phosphoesterase, PA-phosphatase related GE198_RS17655 ENOG4105CKI cobalamin synthesis protein GE198_RS17660 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) GE198_RS17665 ENOG4105KRS Proteinase inhibitor GE198_RS17680 ENOG4105S8Q sugar efflux transporter GE198_RS17685 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein GE198_RS17690 ENOG4105DE4 1-phosphofructokinase GE198_RS17695 ENOG4105DM4 PTS System GE198_RS17705 ENOG4105HMI Membrane GE198_RS17710 ENOG4105DUM transcriptional regulator, lysR family GE198_RS17715 ENOG4108IQI permease GE198_RS17720 ENOG4105D05 Receptor GE198_RS17725 ENOG4105CXY transporter GE198_RS17730 ENOG4105EAC phosphoserine phosphatase GE198_RS17735 ENOG4105EJQ L-serine dehydratase GE198_RS17750 ENOG4105EUJ GTP cyclohydrolase i GE198_RS17755 ENOG4105DHF Membrane GE198_RS17760 ENOG41060NJ transcriptional regulator GE198_RS17765 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator GE198_RS17770 ENOG4105C2J ABC transporter GE198_RS17775 ENOG4107SDZ Galactoside transport system permease protein mglC GE198_RS17780 ENOG4107SJI Dehydrogenase GE198_RS17785 ENOG4105BZ8 glutamate synthase GE198_RS17790 ENOG4105Y9N Membrane GE198_RS17795 ENOG4107GZ4 SanA protein GE198_RS17805 ENOG41067MG lrgb family GE198_RS17835 ENOG4108RXX maleylacetoacetate isomerase GE198_RS17840 ENOG4105MSY salicylate hydroxylase GE198_RS17845 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) GE198_RS17855 ENOG4105ETP RND efflux system, outer membrane lipoprotein GE198_RS17860 ENOG4105H9W Short-chain dehydrogenase reductase Sdr GE198_RS17865 ENOG4105KHU inner membrane protein YohD GE198_RS17870 ENOG41069YE inner membrane protein yohC GE198_RS17875 ENOG41061WM D-Alanyl-D-Alanine GE198_RS17880 ENOG4105CXG d-lactate dehydrogenase GE198_RS17885 ENOG4107QK4 glycoside hydrolase, family 3 domain protein GE198_RS17890 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system GE198_RS17895 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component GE198_RS17900 ENOG4108IJ8 ABC transporter GE198_RS17905 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component GE198_RS17920 ENOG4108HRK Histidine kinase GE198_RS17925 ENOG4108NEV two component transcriptional regulator, LytTR family GE198_RS17930 ENOG4108W15 Protein of unknown function (DUF1456) GE198_RS17940 ENOG4108YCW (LipO)protein GE198_RS17950 ENOG4105D1F ATP-binding protein GE198_RS17965 ENOG4108MQF Chaperone GE198_RS17970 ENOG4105CW0 outer membrane usher protein GE198_RS17975 ENOG410662B Type-1 fimbrial protein GE198_RS17980 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly GE198_RS17985 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase GE198_RS17990 ENOG4105DWF phosphomethylpyrimidine kinase GE198_RS17995 ENOG4105FDP GntR family transcriptional regulator GE198_RS18000 ENOG4108TFM Kinase, PfkB family GE198_RS18005 ENOG4108KD5 ADP-ribosylation crystallin J1 GE198_RS18010 ENOG4105EAA nucleoside GE198_RS18015 ENOG4105EIE fructose-bisphosphate aldolase GE198_RS18030 ENOG41090V3 Tir chaperone protein (CesT) family GE198_RS18040 ENOG4105CFP Peptidase U32 GE198_RS18060 ENOG4105E3W Two component transcriptional regulator (Winged helix family GE198_RS18065 ENOG4105EB3 Histidine kinase GE198_RS18075 ENOG4105BZS acriflavin resistance protein GE198_RS18085 ENOG4105ENT Efflux transporter rnd family, mfp subunit GE198_RS18095 ENOG4105R8A Heat shock protein GE198_RS18100 ENOG4105D03 DNA-3-methyladenine glycosylase II GE198_RS18105 ENOG4105BZU Histidine kinase GE198_RS18120 ENOG4108GAE asmA family GE198_RS18125 ENOG4105EE5 Membrane protein terC GE198_RS18130 ENOG4105DAY polysaccharide export protein GE198_RS18135 ENOG4105KJF protein tyrosine phosphatase GE198_RS18140 ENOG4105D75 Capsular exopolysaccharide family GE198_RS18145 ENOG41090RK glycosyl transferase GE198_RS18150 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB GE198_RS18155 ENOG4107RXY Glycosyl transferase GE198_RS18160 ENOG4108NYJ Colanic acid GE198_RS18165 ENOG4105ECJ Glycosyl Transferase GE198_RS18170 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF GE198_RS18175 ENOG4105C0K Gdp-mannose 4,6-dehydratase GE198_RS18180 ENOG4105C30 Nad-dependent epimerase dehydratase GE198_RS18185 ENOG4105FGF GDP-mannose mannosyl hydrolase GE198_RS18190 ENOG4106CD9 glycosyl transferase group 1 GE198_RS18195 ENOG4105CJT Mannose-1-phosphate guanylyltransferase GE198_RS18200 ENOG4107QKV phosphomannomutase GE198_RS18205 ENOG4105D3Q Sugar transferase GE198_RS18210 ENOG4105PSV Polysaccharide Biosynthesis Protein GE198_RS18215 ENOG4105C74 pyruvyl transferase GE198_RS18220 ENOG4107T8Q Glycosyl transferase (Group 1 GE198_RS18225 ENOG4105G1A colanic acid biosynthesis protein GE198_RS18230 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GE198_RS18235 ENOG4105C1B dTDP-glucose 4-6-dehydratase GE198_RS18240 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase GE198_RS18250 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase GE198_RS18270 ENOG4108KBE Glycosyl transferase, family 2 GE198_RS18275 ENOG4105CJT Mannose-1-phosphate guanylyltransferase GE198_RS18280 ENOG4106ECQ phosphomannomutase GE198_RS18285 ENOG4105D3Q Sugar transferase GE198_RS18295 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) GE198_RS18300 ENOG4105C6Y Udp-glucose 6-dehydrogenase GE198_RS18305 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) GE198_RS18310 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase GE198_RS18325 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) GE198_RS18330 ENOG4105ECC imidazole-glycerol-phosphate dehydratase GE198_RS18355 ENOG4107SRH Nad-dependent epimerase dehydratase GE198_RS18360 ENOG4105EQ1 Transcriptional regulator GE198_RS18370 ENOG4105CUB amino acid GE198_RS18375 ENOG4105CJB Exodeoxyribonuclease I GE198_RS18390 ENOG4108J2R molybdopterin oxidoreductase GE198_RS18395 ENOG4105QAX Iron-sulfur GE198_RS18400 ENOG4108NWD Cytochrome GE198_RS18405 ENOG4105DZ1 carboxypeptidase GE198_RS18410 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) GE198_RS18415 ENOG4105DR8 Membrane GE198_RS18420 ENOG41090HJ UPF0265 protein GE198_RS18425 ENOG4105JZC GHMP kinase GE198_RS18430 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) GE198_RS18435 ENOG4105KTW ethanolamine utilization protein GE198_RS18440 ENOG4105M3W utilization protein GE198_RS18450 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) GE198_RS18460 ENOG4108EKI Dehydrogenase GE198_RS18470 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml GE198_RS18480 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) GE198_RS18490 ENOG4105KNY Microcompartments protein GE198_RS18500 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit GE198_RS18505 ENOG4108ZFT Dehydratase small subunit GE198_RS18510 ENOG4105YCI dehydratase medium subunit GE198_RS18515 ENOG4105DMB glycerol dehydratase GE198_RS18520 ENOG4105EHR propanediol utilization protein pduB GE198_RS18525 ENOG4105KNY Microcompartments protein GE198_RS18530 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) GE198_RS18535 ENOG4107XVH Transcriptional regulator GE198_RS18540 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) GE198_RS18545 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) GE198_RS18550 ENOG41081F0 Precorrin-8x methylmutase GE198_RS18560 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase GE198_RS18565 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase GE198_RS18570 ENOG4105CIA precorrin-4 C(11)-methyltransferase GE198_RS18575 ENOG4108P62 biosynthesis protein (CbiG) GE198_RS18580 ENOG4105E4R Precorrin-3B C17-methyltransferase GE198_RS18585 ENOG4105QUC reductase GE198_RS18590 ENOG4107PPM cobalt chelatase GE198_RS18595 ENOG4105DVK Precorrin-2 c20-methyltransferase GE198_RS18600 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) GE198_RS18605 ENOG4105W4R Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) GE198_RS18610 ENOG4108V4M Cobalt abc transporter GE198_RS18615 ENOG4108JJB ABC transporter GE198_RS18625 ENOG4108YZT Adenosylcobinamide kinase GE198_RS18640 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GE198_RS18650 ENOG41085FC arsR family transcriptional regulator GE198_RS18655 ENOG4108UXE Protein tyrosine phosphatase GE198_RS18670 ENOG4105D6J arsenicaL-resistance protein GE198_RS18685 ENOG4105UQX Mate efflux family protein GE198_RS18695 ENOG4105FYV Amp nucleosidase GE198_RS18755 ENOG4105HVQ Regulatory factor of maltose metabolism GE198_RS18815 ENOG4105KT5 UmuD protein GE198_RS18820 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) GE198_RS18835 ENOG4105FCK Membrane GE198_RS18840 ENOG4105Y0K Inner membrane protein YedR GE198_RS18845 ENOG4105EST Metal Dependent Phosphohydrolase GE198_RS18850 ENOG4105DVF Cytosine-specific methyltransferase GE198_RS18855 ENOG41090BB DNA mismatch endonuclease (vsr) GE198_RS18860 ENOG4105FDR Membrane GE198_RS18865 ENOG4105CKW Inner membrane protein yedI GE198_RS18870 ENOG4105VNZ cytoplasmic protein GE198_RS18880 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase GE198_RS18885 ENOG4105YX3 cellular response to acidity GE198_RS18895 ENOG4107TKS colanic acid capsular biosynthesis activation protein A GE198_RS18900 ENOG4105D19 Role in flagellar biosynthesis (By similarity) GE198_RS18905 ENOG4105VS8 Flagellar biosynthetic protein fliq GE198_RS18910 ENOG4105CN7 Flagellar biosynthetic protein FliP GE198_RS18915 ENOG4105K0P flagellar biosynthesis protein GE198_RS18920 ENOG4105DD5 Flagellar motor switch protein GE198_RS18925 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) GE198_RS18930 ENOG4107ZI8 flagellar basal body-associated protein flil GE198_RS18935 ENOG4105WF4 Flagellar hook-length control protein GE198_RS18940 ENOG4105GSA Flagellar export protein flij GE198_RS18945 ENOG4108JIR Flagellum-specific ATP synthase GE198_RS18950 ENOG41090PJ Flagellar assembly protein GE198_RS18955 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) GE198_RS18960 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) GE198_RS18980 ENOG41066VF YeeE YedE family protein GE198_RS18985 ENOG4105JCU Inherit from NOG: (Lipo)protein GE198_RS18990 ENOG4105E5K Alpha-amylase GE198_RS19000 ENOG4105MQ3 flagellar protein FliS GE198_RS19005 ENOG4105DTS flagellar hook-associated GE198_RS19020 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GE198_RS19025 ENOG4108M9K flagella biosynthesis protein FliZ GE198_RS19030 ENOG4105EAB amino acid AbC transporter GE198_RS19040 ENOG4105E5Q amino acid AbC transporter GE198_RS19045 ENOG4105CDA abc transporter atp-binding protein GE198_RS19050 ENOG4105VJY transcriptional regulator GE198_RS19055 ENOG4105XVG cytoplasmic protein GE198_RS19065 ENOG4105WH1 Two component transcriptional regulator luxr family GE198_RS19110 ENOG4106RHG Yeca family GE198_RS19115 ENOG4105E0U tyrosine-specific transport protein GE198_RS19120 ENOG4105VVZ metal-binding protein GE198_RS19125 ENOG41090A1 ferritin GE198_RS19130 ENOG4105P23 (LipO)protein GE198_RS19140 ENOG4108UEC Ferritin-like protein GE198_RS19155 ENOG4108K4C ec 3.1.3.12 GE198_RS19165 ENOG4108VA4 Universal stress protein GE198_RS19175 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) GE198_RS19180 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region GE198_RS19185 ENOG4107RD7 Flagellar Motor Protein, MotA GE198_RS19190 ENOG4105ER2 Ompa motb domain protein GE198_RS19195 ENOG4105CBS Chea signal transduction histidine kinase GE198_RS19200 ENOG4108V3W Chemotaxis protein, CheW GE198_RS19205 ENOG4105C8Q Methyl-accepting chemotaxis GE198_RS19210 ENOG4105BZU Histidine kinase GE198_RS19220 ENOG4108VYJ response regulator receiver protein GE198_RS19225 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) GE198_RS19230 ENOG4105D00 flagellar biosynthetic protein flhB GE198_RS19235 ENOG4105D7B Flagellar biosynthesis protein flha GE198_RS19240 ENOG4105IRD Flagellar protein FlhE GE198_RS19245 ENOG4105F5H Glycosyl Hydrolase Family 88 GE198_RS19260 ENOG4106ZCM YecM protein GE198_RS19280 ENOG4105WJG Glutathione GE198_RS19285 ENOG41081XQ Conserved Protein GE198_RS19290 ENOG4105D3W isochorismatase GE198_RS19300 ENOG4108TIT dATP pyrophosphohydrolase GE198_RS19305 ENOG4105CDY transcriptional regulatory protein GE198_RS19315 ENOG4107S01 Repressor protein MetJ GE198_RS19335 ENOG4105FAV ABC, transporter GE198_RS19345 ENOG4105NXV High-affinity zinc uptake system protein GE198_RS19350 ENOG4105DR5 peptidase GE198_RS19355 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase GE198_RS19360 ENOG4105CA9 Pyruvate kinase GE198_RS19365 ENOG4106KNT transcriptional regulator GE198_RS19370 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase GE198_RS19375 ENOG4105C01 Dihydroxy-acid dehydratase GE198_RS19380 ENOG4108UHU Aldolase GE198_RS19390 ENOG4105X2V dna damage-inducible protein GE198_RS19400 ENOG4108Q2J Inner membrane protein YebE GE198_RS19405 ENOG4105CUG Oligopeptidase b GE198_RS19410 ENOG4105UMD exodeoxyribonuclease X GE198_RS19415 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GE198_RS19420 ENOG4105MPK DNA polymerase III subunit theta GE198_RS19425 ENOG4105FXM Copper resistance protein GE198_RS19430 ENOG4108PNC copper resistance GE198_RS19435 ENOG4105NKT exported protein GE198_RS19440 ENOG4108I1J Integrase GE198_RS19445 ENOG41076J9 exonuclease VIII GE198_RS19455 ENOG4108YV9 Protein of unknown function (DUF2514) GE198_RS19480 ENOG410685N tail fiber protein GE198_RS19520 ENOG4105DWP Membrane GE198_RS19540 ENOG4105C22 threonyL-tRNA synthetase GE198_RS19545 ENOG4105VEV -acetyltransferase GE198_RS19555 ENOG41064WM Uncharacterized protein YcgX GE198_RS19560 ENOG4106EWC guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling GE198_RS19570 ENOG4108R1E Serine threonine protein phosphatase 1 GE198_RS19575 ENOG4105UVW uncharacterized protein yebW GE198_RS19580 ENOG4105WT8 Protein of unknown function (DUF1480) GE198_RS19590 ENOG4105DY2 Paraquat-inducible protein b GE198_RS19595 ENOG4105H2K paraquat-inducible protein a GE198_RS19600 ENOG4108ZGC gaf domain protein GE198_RS19610 ENOG4105CN1 protease GE198_RS19615 ENOG4105D0M Protease HtpX homolog GE198_RS19620 ENOG4105C0R drug resistance transporter emrb qaca subfamily GE198_RS19625 ENOG4105J4Q Transcriptional regulator GE198_RS19635 ENOG4106CCY Protein MgrB homolog GE198_RS19640 ENOG4105Q3Y exported protein GE198_RS19655 ENOG4105CJN penicillin-binding protein GE198_RS19660 ENOG4105DHI Methyltransferase GE198_RS19675 ENOG4105F3R pts system mannose fructose sorbose family iid GE198_RS19680 ENOG4105ETZ PTS System GE198_RS19685 ENOG4105DAS pts system GE198_RS19690 ENOG4105EE5 Membrane protein terC GE198_RS19695 ENOG4107XTP (EAL) domain protein GE198_RS19700 ENOG4105EJQ L-serine dehydratase GE198_RS19710 ENOG4105CRQ synthase (Component I) GE198_RS19715 ENOG4105X5C UPF0181 protein GE198_RS19720 ENOG4105M4H endoribonuclease L-psp GE198_RS19725 ENOG4105DVT helicase GE198_RS19730 ENOG41072GX Peptidase M22 Glycoprotease GE198_RS19735 ENOG4105Y4Z Outer Membrane Lipoprotein GE198_RS19740 ENOG4105CEY Amp-dependent synthetase and ligase GE198_RS19745 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) GE198_RS19755 ENOG4107QMS site-determining protein GE198_RS19770 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase GE198_RS19785 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation GE198_RS19795 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) GE198_RS19810 ENOG4105ED1 spovr family GE198_RS19820 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GE198_RS19830 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A GE198_RS19840 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) GE198_RS19855 ENOG4105D82 Glutamate dehydrogenase GE198_RS19865 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GE198_RS19870 ENOG4105C4M (Ubiquinol oxidase) subunit I GE198_RS19875 ENOG4105MVP hydrogenase-1 operon protein HyaF GE198_RS19880 ENOG4108VXY Hydrogenase-1 operon protein HyaE GE198_RS19885 ENOG4108USZ hydrogenase GE198_RS19890 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit GE198_RS19900 ENOG4105E3S small subunit GE198_RS19920 ENOG4105C3G gtp-binding protein GE198_RS19930 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria GE198_RS19935 ENOG4105CHH sulfate transporter GE198_RS19940 ENOG4105C5T Phosphoribosyl pyrophosphate synthase GE198_RS19945 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) GE198_RS19955 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) GE198_RS19965 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) GE198_RS19970 ENOG4108YY7 Invasion gene expression up-regulator SirB GE198_RS19975 ENOG41063JG Transcriptional regulator GE198_RS19985 ENOG4105EWV Sodium calcium exchanger membrane region GE198_RS19990 ENOG4105WS7 Cation transport regulator GE198_RS19995 ENOG41090EX DsrE family GE198_RS20000 ENOG4105ID0 Putative invasin GE198_RS20005 ENOG4105WH1 Two component transcriptional regulator luxr family GE198_RS20010 ENOG4105BZU Histidine kinase GE198_RS20015 ENOG4105DQQ Major facilitator superfamily MFS_1 GE198_RS20020 ENOG4105CRU nitrate reductase, alpha subunit GE198_RS20025 ENOG4108IUE nitrate reductase beta subunit GE198_RS20030 ENOG4105R3A Nitrate reductase GE198_RS20035 ENOG41076YT nitrate reductase, gamma subunit GE198_RS20065 ENOG4105CIY formyltetrahydrofolate deformylase GE198_RS20075 ENOG4105D78 K07001 NTE family protein GE198_RS20080 ENOG4105I93 response regulator GE198_RS20085 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GE198_RS20100 ENOG4105C0A alcohol dehydrogenase GE198_RS20105 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein GE198_RS20115 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GE198_RS20120 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GE198_RS20125 ENOG4105C3U ABC transporter GE198_RS20130 ENOG4108JQ7 (ABC) transporter GE198_RS20135 ENOG4105EYW Ion transport protein GE198_RS20155 ENOG4105K9H YciI-like protein GE198_RS20160 ENOG410822N TonB family GE198_RS20165 ENOG4105NAU thioesterase Superfamily protein GE198_RS20180 ENOG4105PI0 Ferredoxin GE198_RS20185 ENOG4105EIF outer membrane protein W GE198_RS20190 ENOG4105WEF catalase GE198_RS20195 ENOG4108N8X transition metal ion binding GE198_RS20200 ENOG4108Z9Z response to DNA damage stimulus GE198_RS20220 ENOG4105DK0 Indole-3-glycerol phosphate synthase GE198_RS20225 ENOG4108EFP Anthranilate synthase component II GE198_RS20230 ENOG4105CRQ synthase (Component I) GE198_RS20240 ENOG4105DB7 PHP domain protein GE198_RS20245 ENOG4107RTD sua5 ycio yrdc ywlc family protein GE198_RS20250 ENOG4105FE9 pseudouridine synthase GE198_RS20255 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase GE198_RS20260 ENOG4105UBK short-chain dehydrogenase reductase GE198_RS20265 ENOG4105ERU peptidase GE198_RS20270 ENOG4105RKX Protein of unknown function (DUF2498) GE198_RS20275 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GE198_RS20280 ENOG4107R11 Transcriptional regulator GE198_RS20295 ENOG4107QM5 aconitate hydratase GE198_RS20300 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) GE198_RS20305 ENOG4105EYK Phosphatidylglycerophosphatase B GE198_RS20310 ENOG4105Q4A inner membrane protein yciS GE198_RS20315 ENOG4105CFV Tetratricopeptide repeat protein GE198_RS20325 ENOG4108ZJT translation initiation factor, Sui1 GE198_RS20330 ENOG41061RM osmotically inducible lipoprotein GE198_RS20335 ENOG4105N2W Transcriptional regulator GE198_RS20345 ENOG4105BZU Histidine kinase GE198_RS20355 ENOG4105Q4T oxidoreductase GE198_RS20360 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH GE198_RS20385 ENOG4108JQ2 peptide transport system atp-binding protein GE198_RS20390 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein GE198_RS20395 ENOG4108EU3 peptide transport system, permease GE198_RS20400 ENOG4108EKA peptide transport system, permease GE198_RS20405 ENOG4108J59 Extracellular solute-binding protein, family 5 GE198_RS20410 ENOG4105E51 psp operon transcriptional activator GE198_RS20415 ENOG41087YS Phage shock protein A GE198_RS20420 ENOG4105YYT phage shock protein B GE198_RS20425 ENOG4105FM1 phage shock protein C GE198_RS20430 ENOG4105NNG Peripheral inner membrane phage-shock protein GE198_RS20435 ENOG4105K8Z Phage shock protein GE198_RS20440 ENOG4105CM6 amino acid regulated cytosolic protein GE198_RS20450 ENOG4108JU8 Transcriptional regulator GE198_RS20455 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) GE198_RS20460 ENOG4107S8C mandelate racemase muconate lactonizing GE198_RS20465 ENOG4105KXI murein peptide amidase A GE198_RS20470 ENOG4107QSI ABC, transporter GE198_RS20480 ENOG4105HEI LysR family (Transcriptional regulator GE198_RS20485 ENOG4105CV8 reductase GE198_RS20490 ENOG4105F6U Short-chain dehydrogenase reductase Sdr GE198_RS20495 ENOG4108XFH Transcriptional regulator GE198_RS20510 ENOG4106PHM regulatory protein GE198_RS20530 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) GE198_RS20550 ENOG4105D64 Mechanosensitive ion channel GE198_RS20555 ENOG4105S5I Membrane GE198_RS20560 ENOG4105Q9Y Universal stress protein GE198_RS20565 ENOG4105DS0 Transcriptional regulator, Crp Fnr family GE198_RS20570 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GE198_RS20575 ENOG4108DG9 Smr protein MutS2 GE198_RS20580 ENOG4105C8Q Methyl-accepting chemotaxis GE198_RS20590 ENOG4105C1J atp-dependent rna helicase GE198_RS20605 ENOG410814C multidrug resistance protein GE198_RS20610 ENOG4108RW8 Universal stress protein F GE198_RS20615 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) GE198_RS20625 ENOG4105IKK cytoplasmic protein GE198_RS20630 ENOG41090X5 Heat shock protein hslJ GE198_RS20635 ENOG4105C5I Dehydrogenase GE198_RS20640 ENOG4107H52 Dicarboxylate transport GE198_RS20645 ENOG410689M (LipO)protein GE198_RS20650 ENOG4105WXT Conserved Protein GE198_RS20665 ENOG4105CQ7 ATP-dependent helicase GE198_RS20670 ENOG4107DB1 DUF218 domain GE198_RS20675 ENOG4105CPW cytochrome b561 GE198_RS20680 ENOG4108WF3 methyltransferase GE198_RS20690 ENOG4105E5Q amino acid AbC transporter GE198_RS20700 ENOG4105E5Q amino acid AbC transporter GE198_RS20705 ENOG4107R0W ABC transporter GE198_RS20715 ENOG4107ZUJ lipid metabolic process GE198_RS20740 ENOG4105C8Q Methyl-accepting chemotaxis GE198_RS20745 ENOG4105DDW LysR family Transcriptional regulator GE198_RS20750 ENOG4105E32 cytoplasmic protein GE198_RS20755 ENOG4105EBR Carboxylesterase GE198_RS20760 ENOG4105DJ9 glucan biosynthesis protein GE198_RS20765 ENOG4108YYC ycei family GE198_RS20780 ENOG4108PQ7 sgc region transcriptional regulator GE198_RS20785 ENOG4108RK0 3-epimerase GE198_RS20790 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) GE198_RS20795 ENOG4106P19 photosystem i assembly btpa GE198_RS20800 ENOG4105DT3 PTS system, galactitol-specific IIc component GE198_RS20805 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) GE198_RS20810 ENOG4105CN9 Peptidase m42 family protein GE198_RS20815 ENOG4108Z9I -acetyltransferase GE198_RS20820 ENOG4107WE3 acetyltransferase YdcK GE198_RS20825 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein GE198_RS20830 ENOG41088CC tellurite resistance protein tehB GE198_RS20835 ENOG4108KKZ (LipO)protein GE198_RS20840 ENOG4105DKK Benzoate GE198_RS20845 ENOG4108JCI Transcriptional regulator GE198_RS20850 ENOG4105CFP Peptidase U32 GE198_RS20855 ENOG4105RR0 Protein of unknown function (DUF2554) GE198_RS20875 ENOG4108UQS dipeptidase GE198_RS20880 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GE198_RS20895 ENOG410654E Membrane GE198_RS20915 ENOG4105R71 cytoplasmic protein GE198_RS20920 ENOG4108T9Y Inner membrane protein ydcZ GE198_RS20925 ENOG4108Z7F N-acetyltransferase GE198_RS20930 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein GE198_RS20935 ENOG4108WYP Transcriptional regulator GE198_RS20940 ENOG4105CHB tonB-dependent Receptor GE198_RS20945 ENOG4108NS2 receptor GE198_RS20950 ENOG4105SUV lipoprotein YgdR GE198_RS20955 ENOG4105C85 amino acid GE198_RS20965 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase GE198_RS20970 ENOG4105JAB phenazine biosynthesis protein, phzf family GE198_RS20975 ENOG4105D0D Nitrate reductase 2, gamma subunit GE198_RS20980 ENOG4108NZN Respiratory nitrate reductase 2 delta chain GE198_RS20985 ENOG4108IUE nitrate reductase beta subunit GE198_RS20990 ENOG4105CRU nitrate reductase, alpha subunit GE198_RS20995 ENOG4107QND Nitrite extrusion protein GE198_RS21030 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GE198_RS21035 ENOG4108MG3 formate dehydrogenase GE198_RS21040 ENOG4105DQ4 alcohol dehydrogenase GE198_RS21055 ENOG4105TPS biofilm-dependent modulation protein GE198_RS21060 ENOG4108Z9K Osmotically inducible protein GE198_RS21065 ENOG4105XXV Acid-resistance protein GE198_RS21075 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) GE198_RS21090 ENOG4105C87 Aminotransferase class I and II GE198_RS21095 ENOG4105DFD Na H antiporter GE198_RS21100 ENOG41060NJ transcriptional regulator GE198_RS21150 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) GE198_RS21175 ENOG4108I5G Major Facilitator superfamily GE198_RS21180 ENOG4105CPQ Dehydrogenase GE198_RS21185 ENOG4105C6F GntR Family Transcriptional Regulator GE198_RS21200 ENOG4105DPX Hydrogenase, large subunit GE198_RS21205 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit GE198_RS21225 ENOG4105MVP hydrogenase-1 operon protein HyaF GE198_RS21250 ENOG4105FFC UPF0187 protein GE198_RS21255 ENOG4105M0C cytoplasmic protein GE198_RS21265 ENOG4105C26 Dehydrogenase GE198_RS21270 ENOG4105EGI Transcriptional regulator GE198_RS21285 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes GE198_RS21290 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF GE198_RS21295 ENOG4106DNR multiple antibiotic resistance protein GE198_RS21300 ENOG4108594 Permease of the drug metabolite transporter GE198_RS21305 ENOG4105E5W Transporter GE198_RS21315 ENOG4108YDI single-species biofilm formation on inanimate substrate GE198_RS21320 ENOG4108WTK competence damage-inducible protein GE198_RS21330 ENOG4105DGW oligopeptidase A GE198_RS21335 ENOG4105EMU Dehydrogenase GE198_RS21340 ENOG4107XBN GntR Family Transcriptional Regulator GE198_RS21345 ENOG41061EV selenium-binding protein YdfZ GE198_RS21350 ENOG4105DEI Mannitol dehydrogenase GE198_RS21360 ENOG4105CPQ Dehydrogenase GE198_RS21380 ENOG4108MK9 spermidine N(1)-acetyltransferase GE198_RS21390 ENOG4105KBG Protein of unknown function (DUF1161) GE198_RS21395 ENOG4107QY8 reductase GE198_RS21400 ENOG4105C3J Cysteine desulfurase GE198_RS21405 ENOG4105QAX Iron-sulfur GE198_RS21410 ENOG4107KGK dmso reductase anchor subunit GE198_RS21415 ENOG4108NEM leader-binding protein dmsD GE198_RS21420 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component GE198_RS21425 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system GE198_RS21430 ENOG4105E90 ABC transporter GE198_RS21435 ENOG4108IJ8 ABC transporter GE198_RS21445 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) GE198_RS21450 ENOG4105DAG ROK family GE198_RS21455 ENOG4106NZI LysR family Transcriptional regulator GE198_RS21460 ENOG4105D94 Major Facilitator Superfamily GE198_RS21470 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap GE198_RS21485 ENOG4105DSF transport protein GE198_RS21490 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GE198_RS21495 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GE198_RS21500 ENOG4105C5D exported protein GE198_RS21505 ENOG4105D5Q Arginine ornithine antiporter GE198_RS21510 ENOG4105RA2 Membrane GE198_RS21515 ENOG4107EXC regulatoR GE198_RS21525 ENOG4105FCK Membrane GE198_RS21530 ENOG4105CPN adenine deaminase GE198_RS21535 ENOG4105JJR Histidine kinase GE198_RS21545 ENOG4105C9Q fumarate hydratase class II GE198_RS21550 ENOG4107GFK fumarate GE198_RS21555 ENOG4105EIP mannose-6-phosphate isomerase GE198_RS21560 ENOG4106J39 exported protein GE198_RS21570 ENOG4105C87 Aminotransferase class I and II GE198_RS21580 ENOG4105D9R oxidoreductase GE198_RS21585 ENOG4106C6R beta-lactam resistance protein GE198_RS21595 ENOG4105M9B inner membrane protein ydgK GE198_RS21620 ENOG4108UQQ Electron transport complex GE198_RS21630 ENOG4105CSM endonuclease III GE198_RS21635 ENOG4105DUX Transporter GE198_RS21640 ENOG4108K3A Glutathione S-transferase GE198_RS21660 ENOG410642K Lysozyme inhibitor GE198_RS21670 ENOG4108XTF Outer Membrane Lipoprotein GE198_RS21685 ENOG4105Y49 secretion protein, HlyD family GE198_RS21690 ENOG4105DSW Fusaric acid resistance protein GE198_RS21695 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GE198_RS21700 ENOG4107RGM aldo keto reductase GE198_RS21705 ENOG4105XZD Fe-S protein GE198_RS21710 ENOG4108WUH Transcriptional regulator, TetR family GE198_RS21715 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GE198_RS21720 ENOG4108UYE Lactoylglutathione lyase GE198_RS21730 ENOG4105M2J Glutaredoxin GE198_RS21735 ENOG4105K4H Nlp p60 protein GE198_RS21740 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GE198_RS21755 ENOG4105F52 Transcriptional regulator GE198_RS21760 ENOG4105CZQ inner membrane transport protein YdhC GE198_RS21765 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase GE198_RS21770 ENOG4108R6K riboflavin synthase, subunit alpha GE198_RS21790 ENOG4108IUF type iii secretion GE198_RS21795 ENOG4108TN6 type iii secretion GE198_RS21800 ENOG41083GP type iii secretion GE198_RS21805 ENOG4108HHI Type III secretion system protein GE198_RS21810 ENOG41063Q7 Type III secretion system protein GE198_RS21825 ENOG4108JIR Flagellum-specific ATP synthase GE198_RS21835 ENOG4106H1D secretion system apparatus protein GE198_RS21840 ENOG4105UQF type iii secretion GE198_RS21845 ENOG4106563 type III secretion system apparatus protein GE198_RS21895 ENOG4106FZW pathogenicity island effector protein GE198_RS21900 ENOG4108SZ7 secretion system effector GE198_RS21910 ENOG4105ZQI secreted protein GE198_RS21940 ENOG4105BZU Histidine kinase GE198_RS21950 ENOG4108XDN Transcriptional regulator GE198_RS21955 ENOG4107SEY Conserved Protein GE198_RS21960 ENOG4105RFR Protein of unknown function (DUF2767) GE198_RS21965 ENOG4108ZXC Two component transcriptional regulator, luxr family GE198_RS21970 ENOG4106AFQ Histidine kinase GE198_RS21975 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GE198_RS21980 ENOG4106WHD Tetrathionate reductase GE198_RS21985 ENOG4105DB1 molybdopterin oxidoreductase GE198_RS21990 ENOG4108RVA ribokinase GE198_RS22000 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) GE198_RS22005 ENOG4105CUB amino acid GE198_RS22010 ENOG4105CA9 Pyruvate kinase GE198_RS22030 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GE198_RS22045 ENOG4105JRK feS assembly protein SufD GE198_RS22050 ENOG4105C3K feS assembly ATPase SufC GE198_RS22055 ENOG4105DIW FeS assembly protein SUFB GE198_RS22060 ENOG4108Z4V iron-sulfur cluster assembly GE198_RS22065 ENOG4108ETY sodium dicarboxylate symporter GE198_RS22070 ENOG410671Z uncharacterized protein ydiH GE198_RS22075 ENOG4105KA0 thioesterase Superfamily protein GE198_RS22080 ENOG4105CQB FAD linked oxidase domain protein GE198_RS22085 ENOG4105IPI Membrane GE198_RS22095 ENOG4105SUA Ydil protein GE198_RS22100 ENOG4105EMV Major Facilitator GE198_RS22105 ENOG4105EMV Major Facilitator GE198_RS22120 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) GE198_RS22125 ENOG4105C1G acyl-Coa dehydrogenase GE198_RS22130 ENOG4105W4W Transcriptional regulator GE198_RS22135 ENOG4105CV7 Electron transfer flavoprotein GE198_RS22140 ENOG4105C10 Electron transfer flavoprotein GE198_RS22145 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GE198_RS22150 ENOG41090P5 ferredoxin-like protein GE198_RS22155 ENOG4105CEY Amp-dependent synthetase and ligase GE198_RS22160 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) GE198_RS22170 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GE198_RS22190 ENOG4108QBX (LipO)protein GE198_RS22200 ENOG4108V06 Glutathione peroxidase GE198_RS22210 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) GE198_RS22215 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) GE198_RS22235 ENOG41082NX 50s ribosomal protein l35 GE198_RS22240 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) GE198_RS22265 ENOG4108NE3 Salt-induced outer membrane protein GE198_RS22270 ENOG4105DE4 1-phosphofructokinase GE198_RS22275 ENOG4105P10 Uncharacterized protein ydiZ GE198_RS22285 ENOG4107PN8 YfeABCD locus regulator GE198_RS22290 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 GE198_RS22295 ENOG4107K5X Membrane-bound metal-dependent hydrolase GE198_RS22300 ENOG4108ETY sodium dicarboxylate symporter GE198_RS22310 ENOG4105CH6 catalase GE198_RS22320 ENOG4105F8D glycoside hydrolase family 4 GE198_RS22325 ENOG4105EZV Transcriptional regulator GE198_RS22330 ENOG4105VCP PTS System GE198_RS22335 ENOG4105CK1 PTS System GE198_RS22340 ENOG4105VZJ PTS System GE198_RS22345 ENOG4105KKI DNA-binding transcriptional activator OsmE GE198_RS22355 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) GE198_RS22360 ENOG4108SPG Periplasmic Protein GE198_RS22375 ENOG4105C26 Dehydrogenase GE198_RS22385 ENOG4105C8Y Acetylornithine aminotransferase GE198_RS22390 ENOG4105CGK Exodeoxyribonuclease III GE198_RS22395 ENOG4105M6F mutator MutT protein GE198_RS22400 ENOG4105MTM Protein of unknown function (DUF1496) GE198_RS22405 ENOG4105D82 Glutamate dehydrogenase GE198_RS22410 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GE198_RS22415 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) GE198_RS22420 ENOG41069NU Nitroreductase GE198_RS22425 ENOG4105D07 Signal peptide peptidase, SppA GE198_RS22430 ENOG4105HDK L-asparaginase GE198_RS22435 ENOG4108RWI nicotinamidase GE198_RS22440 ENOG4105VUT cytoplasmic protein GE198_RS22450 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GE198_RS22455 ENOG4105DSB aldose 1-epimerase GE198_RS22460 ENOG4105CV8 reductase GE198_RS22465 ENOG4105C4X radical SAM domain protein GE198_RS22470 ENOG4105GNX MltA-interacting MipA family protein