locus-tag	class	description
AW59_RS00015	COG3312	ion transport
AW59_RS00075	COG4533	DNA binding
AW59_RS00080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AW59_RS00085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW59_RS00085	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AW59_RS00085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW59_RS00090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW59_RS00095	COG0573	inorganic phosphate transmembrane transporter activity
AW59_RS00100	COG0581	inorganic phosphate transmembrane transporter activity
AW59_RS00110	COG0704	Plays a role in the regulation of phosphate uptake
AW59_RS00115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW59_RS00120	COG2252	PERMEase
AW59_RS00125	COG0431	NADPH-dependent FMN reductase
AW59_RS00130	COG2091	lysine biosynthetic process via aminoadipic acid
AW59_RS00220	COG4948	Mandelate Racemase Muconate Lactonizing
AW59_RS00225	COG2271	Major facilitator Superfamily
AW59_RS00230	COG0561	phosphatase activity
AW59_RS00235	COG2186	Transcriptional regulator
AW59_RS00240	COG3734	2-keto-3-deoxy-galactonokinase
AW59_RS00245	COG0800	Aldolase
AW59_RS00255	COG2271	Major facilitator Superfamily
AW59_RS00260	COG2205	protein histidine kinase activity
AW59_RS00260	COG2198	Histidine kinase
AW59_RS00260	COG0784	Response regulator, receiver
AW59_RS00265	COG1879	ABC-type sugar transport system periplasmic component
AW59_RS00270	COG0745	RESPONSE REGULATOR receiver
AW59_RS00275	COG3005	denitrification pathway
AW59_RS00290	COG1858	cytochrome C peroxidase
AW59_RS00300	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW59_RS00305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW59_RS00310	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW59_RS00320	COG1138	Cytochrome C-type biogenesis protein
AW59_RS00330	COG4235	cytochrome complex assembly
AW59_RS00330	COG3088	subunit of a heme lyase
AW59_RS00335	COG0823	Involved in the tonB-independent uptake of proteins
AW59_RS00340	COG5645	(Lipo)protein
AW59_RS00350	COG0071	Belongs to the small heat shock protein (HSP20) family
AW59_RS00360	COG2149	membrane
AW59_RS00370	COG0641	radical SAM
AW59_RS00380	COG2610	gluconate transmembrane transporter activity
AW59_RS00385	COG0583	DNA-binding transcription factor activity
AW59_RS00395	COG2814	Major facilitator Superfamily
AW59_RS00415	COG0028	Belongs to the TPP enzyme family
AW59_RS00420	COG0440	acetolactate synthase activity
AW59_RS00425	COG1349	DNA-binding transcription factor activity
AW59_RS00435	COG0738	Major facilitator superfamily
AW59_RS00470	COG2188	Transcriptional regulator
AW59_RS00475	COG3711	transcriptional antiterminator
AW59_RS00475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS00480	COG3414	Phosphotransferase system galactitol-specific IIB component
AW59_RS00485	COG3775	system Galactitol-specific IIC component
AW59_RS00520	COG2723	6-phospho-beta-galactosidase activity
AW59_RS00540	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS00540	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW59_RS00545	COG3715	PTS system
AW59_RS00550	COG3716	PTS system mannose fructose sorbose family IID component
AW59_RS00565	COG5464	transposase or invertase
AW59_RS00590	COG1335	isochorismatase
AW59_RS00595	COG3710	Transcriptional regulator
AW59_RS00610	COG2771	luxR family
AW59_RS00635	COG3121	Chaperone
AW59_RS00640	COG3188	usher protein
AW59_RS00650	COG3539	Fimbrial protein
AW59_RS00660	COG3539	Fimbrial protein
AW59_RS00670	COG2211	Major facilitator Superfamily
AW59_RS00675	COG1501	Belongs to the glycosyl hydrolase 31 family
AW59_RS00680	COG2982	Protein involved in outer membrane biogenesis
AW59_RS00685	COG2233	PERMEase
AW59_RS00690	COG0786	glutamate:sodium symporter activity
AW59_RS00695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AW59_RS00700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW59_RS00705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW59_RS00725	COG2860	membrane
AW59_RS00735	COG0583	DNA-binding transcription factor activity
AW59_RS00740	COG1561	YicC-like family, N-terminal region
AW59_RS00765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW59_RS00795	COG1519	Transferase
AW59_RS00800	COG0859	PFAM glycosyl transferase family 9
AW59_RS00805	COG0438	transferase activity, transferring glycosyl groups
AW59_RS00880	COG1216	Glycosyl transferase, family 2
AW59_RS00885	COG2861	carbohydrate metabolic process
AW59_RS00890	COG4942	peptidase
AW59_RS00900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW59_RS00905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AW59_RS00925	COG2271	Major facilitator Superfamily
AW59_RS00935	COG1609	Transcriptional regulator
AW59_RS00940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AW59_RS00950	COG2186	Transcriptional regulator
AW59_RS00980	COG3722	fumarate hydratase activity
AW59_RS00990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS00990	COG2213	PTS system mannitol-specific
AW59_RS00995	COG0625	glutathione transferase activity
AW59_RS01005	COG3276	selenocysteine insertion sequence binding
AW59_RS01010	COG1940	carbohydrate kinase activity
AW59_RS01015	COG1012	belongs to the aldehyde dehydrogenase family
AW59_RS01030	COG0235	Class ii aldolase
AW59_RS01035	COG3623	hexulose-6-phosphate isomerase
AW59_RS01040	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AW59_RS01045	COG1070	Carbohydrate kinase
AW59_RS01050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AW59_RS01055	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AW59_RS01060	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AW59_RS01070	COG2731	YhcH YjgK YiaL family protein
AW59_RS01080	COG1414	Transcriptional regulator
AW59_RS01085	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW59_RS01090	COG3977	Valine--pyruvate aminotransferase
AW59_RS01095	COG0366	Alpha amylase catalytic
AW59_RS01105	COG2992	FlgJ-related protein
AW59_RS01120	COG1070	Carbohydrate kinase
AW59_RS01125	COG4682	membrane
AW59_RS01130	COG3274	enterobacterial common antigen metabolic process
AW59_RS01150	COG2801	Transposase and inactivated derivatives
AW59_RS01175	COG1278	Cold shock
AW59_RS01180	COG2944	sequence-specific DNA binding
AW59_RS01195	COG2885	chlorophyll binding
AW59_RS01200	COG0243	molybdopterin cofactor binding
AW59_RS01205	COG0456	acetyltransferase
AW59_RS01210	COG2818	Glycosylase
AW59_RS01215	COG5571	outer membrane autotransporter
AW59_RS01240	COG1609	Transcriptional regulator
AW59_RS01255	COG0747	negative chemotaxis
AW59_RS01260	COG0601	transmembrane transport
AW59_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW59_RS01270	COG0444	Belongs to the ABC transporter superfamily
AW59_RS01275	COG4608	Belongs to the ABC transporter superfamily
AW59_RS01280	COG0814	amino acid
AW59_RS01285	COG2873	o-acetylhomoserine
AW59_RS01340	COG2200	EAL domain
AW59_RS01340	COG2199	diguanylate cyclase activity
AW59_RS01355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW59_RS01360	COG2200	EAL domain
AW59_RS01365	COG2982	Protein involved in outer membrane biogenesis
AW59_RS01370	COG0477	Major facilitator Superfamily
AW59_RS01375	COG1295	ribonuclease BN
AW59_RS01380	COG0583	DNA-binding transcription factor activity
AW59_RS01385	COG2197	response regulator
AW59_RS01405	COG2188	Transcriptional regulator
AW59_RS01410	COG2222	sugar isomerase
AW59_RS01415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW59_RS01420	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW59_RS01430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW59_RS01435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AW59_RS01440	COG0671	phosphoesterase, PA-phosphatase related
AW59_RS01470	COG0306	phosphate transporter
AW59_RS01475	COG2081	HI0933 family
AW59_RS01480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW59_RS01485	COG0842	Transport permease protein
AW59_RS01485	COG1129	ABC transporter
AW59_RS01490	COG0842	Transport permease protein
AW59_RS01500	COG2091	lysine biosynthetic process via aminoadipic acid
AW59_RS01505	COG0628	permease
AW59_RS01520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AW59_RS01540	COG3714	YhhN family
AW59_RS01550	COG3776	membrane
AW59_RS01555	COG0742	ribosomal rna small subunit methyltransferase
AW59_RS01560	COG0552	protein localization to endoplasmic reticulum
AW59_RS01565	COG2884	Cell division ATP-binding protein ftsE
AW59_RS01570	COG2177	Part of the ABC transporter FtsEX involved in
AW59_RS01650	COG0584	glycerophosphoryl diester phosphodiesterase
AW59_RS01660	COG0405	Gamma-glutamyltransferase
AW59_RS01665	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AW59_RS01680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW59_RS01685	COG1247	-acetyltransferase
AW59_RS01690	COG0673	inositol 2-dehydrogenase activity
AW59_RS01695	COG1741	Belongs to the pirin family
AW59_RS01700	COG1609	Transcriptional regulator
AW59_RS01705	COG3265	gluconokinase activity
AW59_RS01710	COG2610	gluconate transmembrane transporter activity
AW59_RS01740	COG0058	SHG alpha-glucan phosphorylase activity
AW59_RS01745	COG1414	Transcriptional regulator
AW59_RS01750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW59_RS01755	COG0129	dihydroxy-acid dehydratase activity
AW59_RS01765	COG0371	Dehydrogenase
AW59_RS01780	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW59_RS01795	COG1349	DNA-binding transcription factor activity
AW59_RS01805	COG0058	SHG alpha-glucan phosphorylase activity
AW59_RS01810	COG1640	4-alpha-glucanotransferase
AW59_RS01815	COG2610	gluconate transmembrane transporter activity
AW59_RS01835	COG5464	transposase or invertase
AW59_RS01850	COG1918	ferrous iron import across plasma membrane
AW59_RS01855	COG2183	response to ionizing radiation
AW59_RS01860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AW59_RS01880	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AW59_RS01890	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AW59_RS01895	COG1011	Hydrolase
AW59_RS01905	COG0494	nUDIX hydrolase
AW59_RS01910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AW59_RS01915	COG4972	Pilus assembly protein
AW59_RS01920	COG3166	PFAM Fimbrial assembly family protein
AW59_RS01935	COG4796	Type ii and iii secretion system protein
AW59_RS01950	COG3266	domain, Protein
AW59_RS01955	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AW59_RS01960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW59_RS02000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW59_RS02035	COG1289	transmembrane transporter activity
AW59_RS02045	COG1765	OsmC-like protein
AW59_RS02050	COG3954	Phosphoribulokinase
AW59_RS02060	COG0429	hydrolase of the alpha beta-hydrolase fold
AW59_RS02075	COG0488	(ABC) transporter
AW59_RS02090	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AW59_RS02095	COG1047	Peptidyl-prolyl cis-trans
AW59_RS02105	COG0545	Peptidyl-prolyl cis-trans isomerase
AW59_RS02110	COG2964	Protein conserved in bacteria
AW59_RS02165	COG0051	transcription antitermination factor activity, RNA binding
AW59_RS02190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AW59_RS02270	COG0201	protein transport
AW59_RS02310	COG0789	Transcriptional regulator
AW59_RS02315	COG3036	rescue of stalled ribosome
AW59_RS02345	COG0758	DNA mediated transformation
AW59_RS02355	COG0551	DNA topoisomerase type I activity
AW59_RS02375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW59_RS02420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW59_RS02425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW59_RS02430	COG1309	transcriptional regulator
AW59_RS02445	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AW59_RS02465	COG4145	pantothenate transmembrane transporter activity
AW59_RS02470	COG3924	membrane
AW59_RS02475	COG0439	Biotin carboxylase
AW59_RS02480	COG0511	ligase activity, forming carbon-carbon bonds
AW59_RS02495	COG0604	alcohol dehydrogenase
AW59_RS02500	COG2199	diguanylate cyclase activity
AW59_RS02500	COG2200	EAL domain
AW59_RS02510	COG1077	Cell shape determining protein MreB Mrl
AW59_RS02515	COG1792	Involved in formation and maintenance of cell shape
AW59_RS02520	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AW59_RS02535	COG3164	Protein of unknown function
AW59_RS02540	COG0312	modulator of DNA gyrase
AW59_RS02545	COG0583	DNA-binding transcription factor activity
AW59_RS02565	COG2732	(Barnase) inhibitor
AW59_RS02590	COG2188	Transcriptional regulator
AW59_RS02600	COG0471	metal ion transport
AW59_RS02605	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AW59_RS02610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AW59_RS02625	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AW59_RS02640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW59_RS02645	COG3105	Protein conserved in bacteria
AW59_RS02650	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AW59_RS02665	COG0625	glutathione transferase activity
AW59_RS02670	COG2969	positive regulation of protein catabolic process
AW59_RS02700	COG2731	YhcH YjgK YiaL family protein
AW59_RS02705	COG0402	S-adenosylhomocysteine deaminase activity
AW59_RS02710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AW59_RS02715	COG4804	nuclease activity
AW59_RS02720	COG0493	'glutamate synthase
AW59_RS02725	COG0067	glutamate synthase
AW59_RS02725	COG0069	glutamate synthase activity
AW59_RS02725	COG0070	glutamate synthase
AW59_RS02735	COG1242	4 iron, 4 sulfur cluster binding
AW59_RS02740	COG2198	Histidine kinase
AW59_RS02740	COG0784	Response regulator, receiver
AW59_RS02740	COG5002	protein histidine kinase activity
AW59_RS02745	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AW59_RS02750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW59_RS02755	COG0515	serine threonine protein kinase
AW59_RS02760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS02785	COG1137	ATPase activity
AW59_RS02790	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AW59_RS02795	COG3117	lipopolysaccharide transmembrane transporter activity
AW59_RS02810	COG0530	calcium, potassium:sodium antiporter activity
AW59_RS02815	COG1127	ABC transporter
AW59_RS02820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AW59_RS02825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AW59_RS02830	COG2854	intermembrane phospholipid transfer
AW59_RS02835	COG3113	response to antibiotic
AW59_RS02840	COG5007	Belongs to the BolA IbaG family
AW59_RS02850	COG3423	Transcriptional regulator
AW59_RS02855	COG0142	geranyltranstransferase activity
AW59_RS02870	COG0697	spore germination
AW59_RS02880	COG2027	D-alanyl-D-alanine carboxypeptidase
AW59_RS02895	COG1534	Rna-binding protein
AW59_RS02910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW59_RS02920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW59_RS02985	COG0513	Belongs to the DEAD box helicase family
AW59_RS02990	COG0814	amino acid
AW59_RS02995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW59_RS03000	COG0826	peptidase U32
AW59_RS03005	COG0826	peptidase U32
AW59_RS03010	COG3154	lipid carrier protein
AW59_RS03015	COG3153	acetyltransferase
AW59_RS03030	COG0693	protein deglycase activity
AW59_RS03035	COG0702	epimerase
AW59_RS03040	COG2823	Periplasmic or secreted lipoprotein
AW59_RS03060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AW59_RS03070	COG1063	alcohol dehydrogenase
AW59_RS03075	COG3775	system Galactitol-specific IIC component
AW59_RS03080	COG3414	Phosphotransferase system galactitol-specific IIB component
AW59_RS03085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS03100	COG2721	sulfolactate sulfo-lyase activity
AW59_RS03110	COG2084	Dehydrogenase
AW59_RS03115	COG1929	Belongs to the glycerate kinase type-1 family
AW59_RS03130	COG0583	DNA-binding transcription factor activity
AW59_RS03150	COG1882	Formate acetyltransferase
AW59_RS03155	COG1760	l-serine dehydratase
AW59_RS03160	COG0814	amino acid
AW59_RS03175	COG1741	Belongs to the pirin family
AW59_RS03180	COG0583	DNA-binding transcription factor activity
AW59_RS03185	COG3152	Membrane
AW59_RS03190	COG0435	Glutathione S-transferase
AW59_RS03195	COG2259	Doxx family
AW59_RS03205	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AW59_RS03210	COG4575	ribosome binding
AW59_RS03215	COG1422	Protein of unknown function (DUF1090)
AW59_RS03225	COG0586	Pfam SNARE associated Golgi protein
AW59_RS03240	COG0673	inositol 2-dehydrogenase activity
AW59_RS03245	COG2949	membrane
AW59_RS03250	COG1451	nucleotide metabolic process
AW59_RS03260	COG0446	pyridine nucleotide-disulphide oxidoreductase
AW59_RS03260	COG1902	pentaerythritol trinitrate reductase activity
AW59_RS03270	COG0840	transmembrane signaling receptor activity
AW59_RS03275	COG0840	transmembrane signaling receptor activity
AW59_RS03280	COG1695	Transcriptional regulator
AW59_RS03285	COG2375	cellular response to nickel ion
AW59_RS03310	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AW59_RS03325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AW59_RS03340	COG4991	sh3 domain protein
AW59_RS03345	COG3025	triphosphatase activity
AW59_RS03360	COG2268	Band 7 protein
AW59_RS03365	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW59_RS03410	COG3384	dioxygenase
AW59_RS03415	COG0754	glutathionylspermidine amidase activity
AW59_RS03430	COG0494	nUDIX hydrolase
AW59_RS03435	COG3151	Protein conserved in bacteria
AW59_RS03440	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AW59_RS03445	COG3150	esterase
AW59_RS03455	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW59_RS03460	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW59_RS03475	COG3111	PFAM Bacterial OB fold (BOF) protein
AW59_RS03480	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AW59_RS03530	COG0471	metal ion transport
AW59_RS03540	COG1979	alcohol dehydrogenase
AW59_RS03545	COG2207	Transcriptional regulator
AW59_RS03570	COG0848	biopolymer transport protein
AW59_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
AW59_RS03600	COG0840	transmembrane signaling receptor activity
AW59_RS03610	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AW59_RS03615	COG0437	4 iron, 4 sulfur cluster binding
AW59_RS03620	COG5557	Pfam Polysulphide reductase, NrfD
AW59_RS03625	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AW59_RS03630	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AW59_RS03635	COG1773	rubredoxin
AW59_RS03645	COG0298	carbon dioxide binding
AW59_RS03650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW59_RS03660	COG0625	glutathione transferase activity
AW59_RS03665	COG0754	glutathionylspermidine amidase activity
AW59_RS03680	COG0246	Mannitol dehydrogenase
AW59_RS03690	COG2271	Major facilitator Superfamily
AW59_RS03715	COG1012	belongs to the aldehyde dehydrogenase family
AW59_RS03720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW59_RS03730	COG0531	amino acid
AW59_RS03760	COG2301	Belongs to the HpcH HpaI aldolase family
AW59_RS03765	COG2030	dehydratase
AW59_RS03770	COG0427	acetyl-CoA hydrolase
AW59_RS03785	COG1811	Na channel or pump
AW59_RS03795	COG1982	Orn Lys Arg decarboxylase major
AW59_RS03800	COG2211	Major facilitator Superfamily
AW59_RS03825	COG3171	Protein conserved in bacteria
AW59_RS03835	COG0252	asparaginase activity
AW59_RS03845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW59_RS03860	COG0762	integral membrane protein
AW59_RS03865	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AW59_RS03870	COG2805	Type II/IV secretion system protein
AW59_RS03895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AW59_RS03900	COG2356	endonuclease I
AW59_RS03910	COG2814	Major facilitator Superfamily
AW59_RS03930	COG1166	arginine decarboxylase activity
AW59_RS03940	COG2186	Transcriptional regulator
AW59_RS03945	COG4948	Mandelate Racemase Muconate Lactonizing
AW59_RS03950	COG0246	Mannitol dehydrogenase
AW59_RS03955	COG1063	alcohol dehydrogenase
AW59_RS03960	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AW59_RS03965	COG2731	YhcH YjgK YiaL family protein
AW59_RS03970	COG2267	carboxylic ester hydrolase activity
AW59_RS03980	COG0501	Belongs to the peptidase M48B family
AW59_RS03985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AW59_RS03990	COG1122	ATPase activity
AW59_RS03995	COG1122	ATPase activity
AW59_RS04025	COG0191	fructose-bisphosphate aldolase activity
AW59_RS04030	COG0668	transmembrane transport
AW59_RS04040	COG2968	Membrane
AW59_RS04055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW59_RS04060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AW59_RS04080	COG0006	proline dipeptidase activity
AW59_RS04085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW59_RS04090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW59_RS04115	COG2723	6-phospho-beta-galactosidase activity
AW59_RS04125	COG1272	protein, Hemolysin III
AW59_RS04185	COG4942	peptidase
AW59_RS04225	COG3188	usher protein
AW59_RS04260	COG0814	amino acid
AW59_RS04275	COG0183	Belongs to the thiolase family
AW59_RS04285	COG1028	Short-chain dehydrogenase reductase Sdr
AW59_RS04290	COG2814	Major facilitator Superfamily
AW59_RS04295	COG1794	racemase activity, acting on amino acids and derivatives
AW59_RS04300	COG0583	DNA-binding transcription factor activity
AW59_RS04310	COG1609	Transcriptional regulator
AW59_RS04330	COG0667	Aldo Keto reductase
AW59_RS04340	COG0861	Integral membrane protein TerC family
AW59_RS04380	COG2165	general secretion pathway protein
AW59_RS04385	COG4795	General secretion pathway protein
AW59_RS04395	COG4967	type IV pilus modification protein PilV
AW59_RS04400	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AW59_RS04405	COG1025	Belongs to the peptidase M16 family
AW59_RS04410	COG1074	ATP-dependent DNA helicase activity
AW59_RS04415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AW59_RS04425	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW59_RS04440	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AW59_RS04445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AW59_RS04450	COG2962	Rard protein
AW59_RS04455	COG2166	iron-sulfur cluster assembly
AW59_RS04460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW59_RS04470	COG0583	DNA-binding transcription factor activity
AW59_RS04475	COG2363	Small membrane protein
AW59_RS04485	COG1349	DNA-binding transcription factor activity
AW59_RS04505	COG0738	Major facilitator superfamily
AW59_RS04510	COG0235	Class ii aldolase
AW59_RS04515	COG1454	alcohol dehydrogenase
AW59_RS04525	COG1760	l-serine dehydratase
AW59_RS04530	COG0814	amino acid
AW59_RS04535	COG1611	Belongs to the LOG family
AW59_RS04550	COG3098	single-species biofilm formation
AW59_RS04560	COG0716	FMN binding
AW59_RS04565	COG2271	Major facilitator Superfamily
AW59_RS04570	COG4948	Mandelate Racemase Muconate Lactonizing
AW59_RS04575	COG4948	Mandelate Racemase Muconate Lactonizing
AW59_RS04580	COG1929	Belongs to the glycerate kinase type-1 family
AW59_RS04585	COG3850	Histidine kinase
AW59_RS04585	COG2205	protein histidine kinase activity
AW59_RS04585	COG3437	response regulator, receiver
AW59_RS04585	COG4999	Histidine kinase
AW59_RS04595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW59_RS04600	COG3609	addiction module antidote protein, CC2985 family
AW59_RS04610	COG3956	TIGRFAM MazG family protein
AW59_RS04625	COG0602	queuosine metabolic process
AW59_RS04630	COG0321	lipoyl(octanoyl) transferase activity
AW59_RS04630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AW59_RS04635	COG0720	synthase
AW59_RS04660	COG1203	CRISPR-associated helicase, Cas3
AW59_RS04675	COG1857	crispr-associated protein
AW59_RS04690	COG1518	maintenance of DNA repeat elements
AW59_RS04695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW59_RS04700	COG2234	aminopeptidase activity
AW59_RS04755	COG4942	peptidase
AW59_RS04755	COG1388	LysM domain
AW59_RS04770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AW59_RS04775	COG0163	prenyltransferase activity
AW59_RS04785	COG1349	DNA-binding transcription factor activity
AW59_RS04790	COG2084	Dehydrogenase
AW59_RS04800	COG0235	Class ii aldolase
AW59_RS04805	COG3622	Belongs to the hyi family
AW59_RS04810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW59_RS04815	COG2610	gluconate transmembrane transporter activity
AW59_RS04825	COG0477	Major facilitator Superfamily
AW59_RS04890	COG2207	Transcriptional regulator
AW59_RS04980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW59_RS05065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW59_RS05070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW59_RS05075	COG1121	(ABC) transporter
AW59_RS05095	COG0309	Hydrogenase expression formation protein (HypE)
AW59_RS05100	COG0409	Hydrogenase expression formation protein
AW59_RS05105	COG0298	carbon dioxide binding
AW59_RS05110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AW59_RS05125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW59_RS05130	COG0651	ATP synthesis coupled electron transport
AW59_RS05135	COG0650	Formate hydrogenlyase subunit 4
AW59_RS05140	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AW59_RS05140	COG3261	NADH dehydrogenase
AW59_RS05145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW59_RS05150	COG3260	NADH ubiquinone oxidoreductase 20
AW59_RS05160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AW59_RS05170	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW59_RS05175	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AW59_RS05195	COG0517	IMP dehydrogenase activity
AW59_RS05195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AW59_RS05200	COG1349	DNA-binding transcription factor activity
AW59_RS05210	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS05215	COG1028	Short-chain dehydrogenase reductase Sdr
AW59_RS05220	COG3731	PTS system glucitol sorbitol-specific IIA component
AW59_RS05225	COG3732	PTS system glucitol sorbitol-specific
AW59_RS05230	COG3730	PTS system glucitol sorbitol-specific
AW59_RS05235	COG2951	lytic endotransglycosylase activity
AW59_RS05240	COG1546	Belongs to the CinA family
AW59_RS05260	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AW59_RS05290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW59_RS05295	COG1238	metal cluster binding
AW59_RS05315	COG2814	Major facilitator Superfamily
AW59_RS05320	COG1566	PFAM secretion protein HlyD family protein
AW59_RS05325	COG1846	Transcriptional regulator
AW59_RS05330	COG2814	Major facilitator Superfamily
AW59_RS05375	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW59_RS05385	COG4575	ribosome binding
AW59_RS05410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW59_RS05415	COG0640	Transcriptional regulator
AW59_RS05420	COG0401	homolog of Blt101
AW59_RS05425	COG1652	LysM domain
AW59_RS05430	COG1802	Transcriptional regulator
AW59_RS05435	COG1113	amino acid transport
AW59_RS05440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW59_RS05445	COG1012	belongs to the aldehyde dehydrogenase family
AW59_RS05450	COG0579	oxidoreductase
AW59_RS05490	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AW59_RS05505	COG2990	Protein conserved in bacteria
AW59_RS05525	COG2819	hydrolase of the alpha beta superfamily
AW59_RS05620	COG0582	viral genome integration into host DNA
AW59_RS05630	COG4974	Belongs to the 'phage' integrase family
AW59_RS05665	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW59_RS05705	COG4695	Portal protein
AW59_RS05845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW59_RS05870	COG2867	negative regulation of translational initiation
AW59_RS05885	COG0497	DNA recombination
AW59_RS05905	COG4536	flavin adenine dinucleotide binding
AW59_RS05910	COG4137	Cytochrome C assembly protein
AW59_RS05915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AW59_RS05940	COG2199	diguanylate cyclase activity
AW59_RS05955	COG0287	Prephenate dehydrogenase
AW59_RS05955	COG1605	Chorismate mutase
AW59_RS05965	COG1605	Chorismate mutase
AW59_RS05965	COG0077	Prephenate dehydratase
AW59_RS05970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AW59_RS05975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AW59_RS05990	COG0542	response to heat
AW59_RS06020	COG0477	Major facilitator Superfamily
AW59_RS06025	COG5544	Lipoprotein
AW59_RS06030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW59_RS06040	COG3148	PFAM DTW domain containing protein
AW59_RS06045	COG3118	belongs to the thioredoxin family
AW59_RS06050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW59_RS06070	COG0583	DNA-binding transcription factor activity
AW59_RS06075	COG0513	Belongs to the DEAD box helicase family
AW59_RS06085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AW59_RS06105	COG3086	response to oxidative stress
AW59_RS06145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW59_RS06150	COG0583	DNA-binding transcription factor activity
AW59_RS06155	COG2223	nitrite transmembrane transporter activity
AW59_RS06160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW59_RS06165	COG1737	Transcriptional regulator
AW59_RS06175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW59_RS06175	COG1263	PTS System
AW59_RS06180	COG0560	Phosphoserine phosphatase
AW59_RS06205	COG2205	protein histidine kinase activity
AW59_RS06210	COG3170	Tfp pilus assembly protein FimV
AW59_RS06215	COG2204	response regulator
AW59_RS06220	COG0347	Belongs to the P(II) protein family
AW59_RS06225	COG3104	oligopeptide transport
AW59_RS06235	COG0531	amino acid
AW59_RS06240	COG3710	Transcriptional regulator
AW59_RS06245	COG1017	nitric oxide dioxygenase activity
AW59_RS06245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW59_RS06255	COG2814	Major facilitator Superfamily
AW59_RS06260	COG3711	transcriptional antiterminator
AW59_RS06270	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AW59_RS06315	COG0822	iron-sulfur transferase activity
AW59_RS06335	COG0633	Ferredoxin
AW59_RS06340	COG2975	iron-sulfur cluster assembly
AW59_RS06360	COG2897	thiosulfate sulfurtransferase activity
AW59_RS06365	COG2373	Large extracellular alpha-helical protein
AW59_RS06370	COG4953	penicillin-binding protein 1C
AW59_RS06375	COG0243	molybdopterin cofactor binding
AW59_RS06380	COG0437	4 iron, 4 sulfur cluster binding
AW59_RS06420	COG2976	Protein conserved in bacteria
AW59_RS06435	COG1645	bacterial-type flagellum-dependent swarming motility
AW59_RS06470	COG0517	IMP dehydrogenase activity
AW59_RS06470	COG0516	GMP reductase activity
AW59_RS06480	COG2801	Transposase and inactivated derivatives
AW59_RS06500	COG2200	EAL domain
AW59_RS06515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AW59_RS06530	COG2233	PERMEase
AW59_RS06540	COG1393	Belongs to the ArsC family
AW59_RS06550	COG0628	permease
AW59_RS06555	COG3835	regulator
AW59_RS06560	COG2610	gluconate transmembrane transporter activity
AW59_RS06565	COG1929	Belongs to the glycerate kinase type-1 family
AW59_RS06570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AW59_RS06575	COG2716	regulation of RNA biosynthetic process
AW59_RS06585	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AW59_RS06595	COG2321	neutral zinc metallopeptidase
AW59_RS06615	COG1393	Belongs to the ArsC family
AW59_RS06620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW59_RS06625	COG3850	Histidine kinase
AW59_RS06630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW59_RS06630	COG0493	'glutamate synthase
AW59_RS06635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW59_RS06645	COG5342	invasion associated locus B
AW59_RS06655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AW59_RS06790	COG2837	iron assimilation
AW59_RS06810	COG4208	sulfate ABC transporter
AW59_RS06815	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AW59_RS06865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS06895	COG3530	Putative quorum-sensing-regulated virulence factor
AW59_RS06900	COG0385	Bile acid
AW59_RS06905	COG0583	DNA-binding transcription factor activity
AW59_RS06915	COG2211	Major facilitator Superfamily
AW59_RS06925	COG0583	DNA-binding transcription factor activity
AW59_RS06955	COG3415	Transposase
AW59_RS06960	COG3415	Transposase
AW59_RS06975	COG2200	EAL domain
AW59_RS06975	COG2199	diguanylate cyclase activity
AW59_RS06980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW59_RS06995	COG0667	Aldo Keto reductase
AW59_RS07000	COG3961	Belongs to the TPP enzyme family
AW59_RS07015	COG0436	Aminotransferase
AW59_RS07020	COG1560	Kdo2-lipid A biosynthetic process
AW59_RS07065	COG2116	formate transmembrane transporter activity
AW59_RS07080	COG3691	Protein conserved in bacteria
AW59_RS07095	COG2062	phosphohistidine phosphatase, SixA
AW59_RS07120	COG0730	response to heat
AW59_RS07125	COG3101	peptidyl-lysine hydroxylation
AW59_RS07140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW59_RS07160	COG3423	Transcriptional regulator
AW59_RS07185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW59_RS07195	COG0586	Pfam SNARE associated Golgi protein
AW59_RS07205	COG0285	dihydrofolate synthase activity
AW59_RS07210	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AW59_RS07215	COG1286	toxin biosynthetic process
AW59_RS07220	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AW59_RS07225	COG3829	transcription factor binding
AW59_RS07235	COG0531	amino acid
AW59_RS07240	COG3457	Alanine racemase
AW59_RS07245	COG0833	amino acid
AW59_RS07280	COG1090	epimerase
AW59_RS07285	COG0625	glutathione transferase activity
AW59_RS07290	COG0625	glutathione transferase activity
AW59_RS07295	COG0622	Phosphoesterase
AW59_RS07305	COG1609	Transcriptional regulator
AW59_RS07315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS07325	COG3037	sugar-specific permease SgaT UlaA
AW59_RS07330	COG3959	Transketolase, thiamine diphosphate binding domain
AW59_RS07335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AW59_RS07340	COG1288	antiporter activity
AW59_RS07365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW59_RS07370	COG0471	metal ion transport
AW59_RS07370	COG0490	domain, Protein
AW59_RS07380	COG0436	Aminotransferase
AW59_RS07390	COG0583	DNA-binding transcription factor activity
AW59_RS07440	COG0839	Belongs to the complex I subunit 6 family
AW59_RS07450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW59_RS07455	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW59_RS07465	COG0835	chemotaxis
AW59_RS07465	COG0784	Response regulator, receiver
AW59_RS07475	COG2153	protein acetylation
AW59_RS07480	COG4575	ribosome binding
AW59_RS07485	COG1169	isochorismate synthase
AW59_RS07575	COG1414	Transcriptional regulator
AW59_RS07585	COG2271	Major facilitator Superfamily
AW59_RS07605	COG0247	lactate metabolic process
AW59_RS07615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW59_RS07620	COG2271	Major facilitator Superfamily
AW59_RS07625	COG0584	glycerophosphoryl diester phosphodiesterase
AW59_RS07630	COG0583	DNA-binding transcription factor activity
AW59_RS07635	COG2814	Major facilitator Superfamily
AW59_RS07640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW59_RS07670	COG4948	Mandelate Racemase Muconate Lactonizing
AW59_RS07690	COG0642	Histidine kinase
AW59_RS07690	COG2198	Histidine kinase
AW59_RS07715	COG4615	Cyclic peptide transporter
AW59_RS07725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW59_RS07725	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW59_RS07730	COG3062	negative regulation of establishment of protein localization
AW59_RS07740	COG0437	4 iron, 4 sulfur cluster binding
AW59_RS07745	COG0348	domain, Protein
AW59_RS07750	COG3043	anaerobic respiration
AW59_RS07755	COG3005	denitrification pathway
AW59_RS07760	COG4133	protoheme IX ABC transporter activity
AW59_RS07765	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW59_RS07770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW59_RS07775	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW59_RS07785	COG1138	Cytochrome C-type biogenesis protein
AW59_RS07795	COG4235	cytochrome complex assembly
AW59_RS07795	COG3088	subunit of a heme lyase
AW59_RS07800	COG2197	response regulator
AW59_RS07820	COG5301	cellulose 1,4-beta-cellobiosidase activity
AW59_RS07865	COG1061	Type III restriction enzyme res subunit
AW59_RS07875	COG2814	Major facilitator Superfamily
AW59_RS07890	COG4172	Belongs to the ABC transporter superfamily
AW59_RS07895	COG4239	(ABC) transporter, permease
AW59_RS07900	COG4174	ABC transporter (Permease)
AW59_RS07905	COG4166	transmembrane transport
AW59_RS07910	COG2200	EAL domain
AW59_RS07915	COG0791	NLP P60 protein
AW59_RS07920	COG0671	phosphoesterase, PA-phosphatase related
AW59_RS07925	COG0523	cobalamin synthesis protein
AW59_RS07960	COG1105	Belongs to the carbohydrate kinase PfkB family
AW59_RS07965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW59_RS07965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW59_RS07965	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AW59_RS07975	COG2855	membrane
AW59_RS07980	COG0583	DNA-binding transcription factor activity
AW59_RS07985	COG0833	amino acid
AW59_RS07990	COG4771	TonB-dependent receptor
AW59_RS07995	COG2271	Major facilitator Superfamily
AW59_RS08000	COG0560	Phosphoserine phosphatase
AW59_RS08005	COG1760	l-serine dehydratase
AW59_RS08025	COG2311	Membrane
AW59_RS08055	COG0493	'glutamate synthase
AW59_RS08065	COG2949	membrane
AW59_RS08075	COG1346	cytolysis
AW59_RS08090	COG2271	Major facilitator Superfamily
AW59_RS08105	COG0625	glutathione transferase activity
AW59_RS08110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW59_RS08120	COG1538	Outer membrane efflux protein
AW59_RS08125	COG1028	Short-chain dehydrogenase reductase Sdr
AW59_RS08130	COG0586	Pfam SNARE associated Golgi protein
AW59_RS08140	COG1686	Belongs to the peptidase S11 family
AW59_RS08145	COG0277	FAD linked oxidase domain protein
AW59_RS08155	COG1732	Glycine betaine
AW59_RS08160	COG1174	glycine betaine transport
AW59_RS08165	COG1125	glycine betaine transport
AW59_RS08170	COG1174	glycine betaine transport
AW59_RS08185	COG3275	phosphorelay sensor kinase activity
AW59_RS08195	COG4807	Protein conserved in bacteria
AW59_RS08205	COG4808	Protein conserved in bacteria
AW59_RS08230	COG3121	Chaperone
AW59_RS08235	COG3188	usher protein
AW59_RS08245	COG5455	response to cobalt ion
AW59_RS08250	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AW59_RS08260	COG2188	Transcriptional regulator
AW59_RS08265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW59_RS08270	COG1397	ADP-ribosylglycohydrolase
AW59_RS08275	COG2211	Major facilitator Superfamily
AW59_RS08280	COG1830	Aldolase
AW59_RS08310	COG0826	peptidase U32
AW59_RS08330	COG0745	RESPONSE REGULATOR receiver
AW59_RS08335	COG2205	protein histidine kinase activity
AW59_RS08360	COG0443	Heat shock 70 kDa protein
AW59_RS08365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW59_RS08370	COG3447	MASE1 domain protein
AW59_RS08370	COG5001	Diguanylate cyclase
AW59_RS08370	COG5002	protein histidine kinase activity
AW59_RS08385	COG2982	Protein involved in outer membrane biogenesis
AW59_RS08390	COG1253	flavin adenine dinucleotide binding
AW59_RS08410	COG0463	Glycosyl transferase, family 2
AW59_RS08415	COG1045	serine acetyltransferase
AW59_RS08420	COG0438	transferase activity, transferring glycosyl groups
AW59_RS08430	COG1216	Glycosyl transferase, family 2
AW59_RS08435	COG0110	maltose O-acetyltransferase activity
AW59_RS08440	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AW59_RS08445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW59_RS08455	COG0297	glycogen (starch) synthase activity
AW59_RS08470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AW59_RS08475	COG2244	polysaccharide biosynthetic process
AW59_RS08480	COG2327	Polysaccharide pyruvyl transferase
AW59_RS08615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW59_RS08620	COG0583	DNA-binding transcription factor activity
AW59_RS08625	COG0531	amino acid
AW59_RS08630	COG2925	Exonuclease
AW59_RS08665	COG1289	transmembrane transporter activity
AW59_RS08700	COG4656	Part of a membrane complex involved in electron transport
AW59_RS08720	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AW59_RS08735	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AW59_RS08865	COG1122	ATPase activity
AW59_RS08895	COG0640	Transcriptional regulator
AW59_RS08900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW59_RS08915	COG0798	PFAM Bile acid sodium symporter
AW59_RS08935	COG0534	Mate efflux family protein
AW59_RS08950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AW59_RS09000	COG3423	Transcriptional regulator
AW59_RS09025	COG0582	viral genome integration into host DNA
AW59_RS09040	COG0582	viral genome integration into host DNA
AW59_RS09080	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AW59_RS09090	COG1418	mRNA catabolic process
AW59_RS09095	COG0270	DNA (cytosine-5-)-methyltransferase activity
AW59_RS09100	COG3727	T/G mismatch-specific endonuclease activity
AW59_RS09105	COG0697	spore germination
AW59_RS09110	COG2354	Protein conserved in bacteria
AW59_RS09115	COG5475	Uncharacterized small protein (DUF2158)
AW59_RS09220	COG0425	Belongs to the sulfur carrier protein TusA family
AW59_RS09275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW59_RS09285	COG0765	amino acid transport
AW59_RS09290	COG1126	abc transporter atp-binding protein
AW59_RS09295	COG2197	response regulator
AW59_RS09310	COG2197	response regulator
AW59_RS09355	COG3318	Belongs to the UPF0149 family
AW59_RS09355	COG3012	SEC-C Motif Domain Protein
AW59_RS09360	COG0814	amino acid
AW59_RS09370	COG1528	Iron-storage protein
AW59_RS09385	COG1528	Iron-storage protein
AW59_RS09485	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AW59_RS09500	COG3102	Protein conserved in bacteria
AW59_RS09520	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AW59_RS09525	COG1801	Protein of unknown function DUF72
AW59_RS09530	COG1335	isochorismatase
AW59_RS09540	COG0494	nUDIX hydrolase
AW59_RS09575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW59_RS09585	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AW59_RS09590	COG0739	heme binding
AW59_RS09595	COG1560	Kdo2-lipid A biosynthetic process
AW59_RS09605	COG1737	Transcriptional regulator
AW59_RS09610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW59_RS09615	COG0129	dihydroxy-acid dehydratase activity
AW59_RS09620	COG0800	Aldolase
AW59_RS09630	COG3141	response to X-ray
AW59_RS09640	COG2979	Protein of unknown function (DUF533)
AW59_RS09645	COG1770	oligopeptidase
AW59_RS09650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW59_RS09655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW59_RS09665	COG2372	response to copper ion
AW59_RS09670	COG1276	copper resistance
AW59_RS09685	COG0582	viral genome integration into host DNA
AW59_RS09690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW59_RS09770	COG3328	transposase activity
AW59_RS09785	COG0454	-acetyltransferase
AW59_RS09795	COG5562	phage envelope protein
AW59_RS09830	COG3008	intermembrane lipid transfer
AW59_RS09835	COG2995	paraquat-inducible protein a
AW59_RS09840	COG1956	GAF domain-containing protein
AW59_RS09860	COG2814	Major facilitator Superfamily
AW59_RS09865	COG1414	Transcriptional regulator
AW59_RS09895	COG0768	penicillin binding
AW59_RS09900	COG2226	methyltransferase
AW59_RS09915	COG3716	PTS system mannose fructose sorbose family IID component
AW59_RS09920	COG3715	PTS system
AW59_RS09925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS09925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW59_RS09935	COG1253	flavin adenine dinucleotide binding
AW59_RS09940	COG2200	EAL domain
AW59_RS09945	COG1760	l-serine dehydratase
AW59_RS09965	COG0251	oxidation-reduction process
AW59_RS09970	COG1199	ATP-dependent helicase activity
AW59_RS09980	COG3065	identical protein binding
AW59_RS09990	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AW59_RS10000	COG2894	cell division
AW59_RS10015	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW59_RS10055	COG2719	SpoVR family
AW59_RS10075	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW59_RS10100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW59_RS10110	COG1294	oxidase, subunit
AW59_RS10115	COG1271	oxidase subunit
AW59_RS10120	COG1773	rubredoxin
AW59_RS10125	COG1999	signal sequence binding
AW59_RS10130	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AW59_RS10135	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AW59_RS10145	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AW59_RS10165	COG0012	GTP binding
AW59_RS10180	COG0659	secondary active sulfate transmembrane transporter activity
AW59_RS10230	COG0387	Pfam Sodium calcium exchanger
AW59_RS10235	COG4572	Cation transport regulator
AW59_RS10240	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AW59_RS10245	COG4932	domain protein
AW59_RS10250	COG2197	response regulator
AW59_RS10255	COG3850	Histidine kinase
AW59_RS10260	COG2223	nitrite transmembrane transporter activity
AW59_RS10265	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AW59_RS10270	COG1140	nitrate reductase beta subunit
AW59_RS10275	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AW59_RS10280	COG2181	nitrate reductase activity
AW59_RS10310	COG0788	formyltetrahydrofolate deformylase activity
AW59_RS10320	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW59_RS10325	COG0745	RESPONSE REGULATOR receiver
AW59_RS10330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW59_RS10345	COG1012	belongs to the aldehyde dehydrogenase family
AW59_RS10345	COG1454	alcohol dehydrogenase
AW59_RS10350	COG2095	MarC family integral membrane protein
AW59_RS10380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW59_RS10395	COG2350	Protein conserved in bacteria
AW59_RS10420	COG0727	PFAM Uncharacterised protein family (UPF0153)
AW59_RS10430	COG3546	catalase activity
AW59_RS10435	COG3685	Protein conserved in bacteria
AW59_RS10440	COG3685	Protein conserved in bacteria
AW59_RS10445	COG3729	General stress protein
AW59_RS10480	COG0009	L-threonylcarbamoyladenylate synthase
AW59_RS10495	COG1028	Short-chain dehydrogenase reductase Sdr
AW59_RS10500	COG0616	signal peptide processing
AW59_RS10535	COG0671	phosphoesterase, PA-phosphatase related
AW59_RS10540	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AW59_RS10545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AW59_RS10565	COG1349	DNA-binding transcription factor activity
AW59_RS10575	COG5001	Diguanylate cyclase
AW59_RS10585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW59_RS10585	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW59_RS10640	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW59_RS10645	COG1842	Phage shock protein A
AW59_RS10655	COG1983	PspC domain protein
AW59_RS10665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW59_RS10670	COG3106	COG3106 Predicted ATPase
AW59_RS10690	COG4948	Mandelate Racemase Muconate Lactonizing
AW59_RS10695	COG2866	Carboxypeptidase
AW59_RS10700	COG4166	transmembrane transport
AW59_RS10710	COG0583	DNA-binding transcription factor activity
AW59_RS10715	COG0656	L-ascorbic acid biosynthetic process
AW59_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
AW59_RS10725	COG1309	transcriptional regulator
AW59_RS10760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AW59_RS10780	COG0668	transmembrane transport
AW59_RS10785	COG3182	Iron-regulated membrane protein
AW59_RS10805	COG2840	Smr protein MutS2
AW59_RS10810	COG0840	transmembrane signaling receptor activity
AW59_RS10820	COG0513	Belongs to the DEAD box helicase family
AW59_RS10835	COG2076	Multidrug Resistance protein
AW59_RS10850	COG0674	pyruvate-flavodoxin oxidoreductase activity
AW59_RS10850	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AW59_RS10850	COG1013	pyruvate-flavodoxin oxidoreductase activity
AW59_RS10850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW59_RS10860	COG3042	response to heat
AW59_RS10865	COG3187	Heat shock protein
AW59_RS10870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW59_RS10875	COG2911	Protein conserved in bacteria
AW59_RS10885	COG3784	Protein of unknown function (DUF1318)
AW59_RS10900	COG1643	Atp-dependent helicase
AW59_RS10905	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AW59_RS10910	COG3038	cytochrome b561
AW59_RS10915	COG0500	methyltransferase
AW59_RS10925	COG0765	amino acid transport
AW59_RS10935	COG0765	amino acid transport
AW59_RS10940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW59_RS10970	COG0840	transmembrane signaling receptor activity
AW59_RS10975	COG0583	DNA-binding transcription factor activity
AW59_RS10980	COG5383	Protein conserved in bacteria
AW59_RS10985	COG2272	Belongs to the type-B carboxylesterase lipase family
AW59_RS10990	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AW59_RS10995	COG2353	YceI-like domain
AW59_RS11000	COG1304	FMN binding
AW59_RS11010	COG1349	DNA-binding transcription factor activity
AW59_RS11015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW59_RS11020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS11025	COG0434	BtpA family
AW59_RS11030	COG3775	system Galactitol-specific IIC component
AW59_RS11035	COG3414	Phosphotransferase system galactitol-specific IIB component
AW59_RS11045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW59_RS11050	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW59_RS11055	COG1275	C4-dicarboxylate transporter malic acid transport protein
AW59_RS11060	COG0500	methyltransferase
AW59_RS11075	COG1396	sequence-specific DNA binding
AW59_RS11080	COG0826	peptidase U32
AW59_RS11105	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AW59_RS11110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW59_RS11145	COG3238	Protein conserved in bacteria
AW59_RS11155	COG2130	NADP-dependent
AW59_RS11160	COG1802	Transcriptional regulator
AW59_RS11165	COG4772	TonB-dependent receptor
AW59_RS11170	COG3391	amine dehydrogenase activity
AW59_RS11200	COG2181	nitrate reductase activity
AW59_RS11205	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AW59_RS11210	COG1140	nitrate reductase beta subunit
AW59_RS11215	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AW59_RS11250	COG3383	formate dehydrogenase (NAD+) activity
AW59_RS11250	COG0243	molybdopterin cofactor binding
AW59_RS11255	COG3383	formate dehydrogenase (NAD+) activity
AW59_RS11255	COG0243	molybdopterin cofactor binding
AW59_RS11260	COG0437	4 iron, 4 sulfur cluster binding
AW59_RS11265	COG2864	formate dehydrogenase
AW59_RS11270	COG1064	alcohol dehydrogenase
AW59_RS11290	COG1764	response to oxidative stress
AW59_RS11305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AW59_RS11320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW59_RS11325	COG1757	Na H antiporter
AW59_RS11330	COG1609	Transcriptional regulator
AW59_RS11380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AW59_RS11405	COG2271	Major facilitator Superfamily
AW59_RS11410	COG1063	alcohol dehydrogenase
AW59_RS11415	COG2186	Transcriptional regulator
AW59_RS11425	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AW59_RS11430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AW59_RS11455	COG1773	rubredoxin
AW59_RS11480	COG3781	membrane
AW59_RS11495	COG1012	belongs to the aldehyde dehydrogenase family
AW59_RS11500	COG0583	DNA-binding transcription factor activity
AW59_RS11535	COG2814	Major facilitator Superfamily
AW59_RS11545	COG3111	PFAM Bacterial OB fold (BOF) protein
AW59_RS11550	COG1546	Belongs to the CinA family
AW59_RS11555	COG3729	General stress protein
AW59_RS11565	COG4221	oxidoreductase activity
AW59_RS11570	COG1802	Transcriptional regulator
AW59_RS11580	COG0246	Mannitol dehydrogenase
AW59_RS11585	COG0477	Major facilitator Superfamily
AW59_RS11590	COG1063	alcohol dehydrogenase
AW59_RS11610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW59_RS11625	COG0243	molybdopterin cofactor binding
AW59_RS11630	COG0243	molybdopterin cofactor binding
AW59_RS11635	COG0437	4 iron, 4 sulfur cluster binding
AW59_RS11640	COG3302	dmso reductase anchor subunit
AW59_RS11680	COG1940	carbohydrate kinase activity
AW59_RS11685	COG0583	DNA-binding transcription factor activity
AW59_RS11690	COG2814	Major facilitator Superfamily
AW59_RS11700	COG3591	Belongs to the peptidase S1B family
AW59_RS11715	COG0628	permease
AW59_RS11720	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AW59_RS11725	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AW59_RS11735	COG0531	amino acid
AW59_RS11740	COG3136	membrane protein required for alginate biosynthesis
AW59_RS11745	COG0745	RESPONSE REGULATOR receiver
AW59_RS11750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AW59_RS11755	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW59_RS11760	COG2205	protein histidine kinase activity
AW59_RS11785	COG5339	Protein conserved in bacteria
AW59_RS11790	COG1609	Transcriptional regulator
AW59_RS11795	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW59_RS11805	COG0673	inositol 2-dehydrogenase activity
AW59_RS11855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AW59_RS11865	COG0625	glutathione transferase activity
AW59_RS11885	COG3895	Periplasmic Protein
AW59_RS11910	COG1566	PFAM secretion protein HlyD family protein
AW59_RS11925	COG4989	oxidoreductase activity
AW59_RS11930	COG3313	Fe-S protein
AW59_RS11935	COG1309	transcriptional regulator
AW59_RS11940	COG1902	pentaerythritol trinitrate reductase activity
AW59_RS11955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AW59_RS11960	COG0791	NLP P60 protein
AW59_RS11975	COG0583	DNA-binding transcription factor activity
AW59_RS11980	COG2814	Major facilitator Superfamily
AW59_RS11985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AW59_RS11990	COG0307	riboflavin synthase, alpha
AW59_RS12170	COG0789	Transcriptional regulator
AW59_RS12175	COG3272	Protein of unknown function (DUF1722)
AW59_RS12210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW59_RS12220	COG2267	carboxylic ester hydrolase activity
AW59_RS12225	COG0531	amino acid
AW59_RS12250	COG1376	ErfK ybiS ycfS ynhG family protein
AW59_RS12265	COG0719	Fe-S assembly protein
AW59_RS12270	COG0396	ATPase activity
AW59_RS12275	COG0719	Fe-S assembly protein
AW59_RS12280	COG0316	Belongs to the HesB IscA family
AW59_RS12285	COG1823	symporter activity
AW59_RS12295	COG2050	protein possibly involved in aromatic compounds catabolism
AW59_RS12300	COG0247	lactate metabolic process
AW59_RS12300	COG0277	FAD linked oxidase domain protein
AW59_RS12305	COG0628	permease
AW59_RS12320	COG0738	Major facilitator superfamily
AW59_RS12325	COG2271	Major facilitator Superfamily
AW59_RS12340	COG4670	ketone body catabolic process
AW59_RS12345	COG1960	acyl-CoA dehydrogenase activity
AW59_RS12350	COG2207	Transcriptional regulator
AW59_RS12350	COG1917	Cupin 2, conserved barrel domain protein
AW59_RS12355	COG2086	electron transfer activity
AW59_RS12360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AW59_RS12365	COG0644	oxidoreductase
AW59_RS12370	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AW59_RS12375	COG0318	PFAM AMP-dependent synthetase and ligase
AW59_RS12380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AW59_RS12380	COG0574	Belongs to the PEP-utilizing enzyme family
AW59_RS12395	COG4256	Hemin uptake protein
AW59_RS12410	COG0791	NLP P60 protein
AW59_RS12420	COG0386	Belongs to the glutathione peroxidase family
AW59_RS12480	COG3137	Salt-induced outer membrane protein
AW59_RS12485	COG1105	Belongs to the carbohydrate kinase PfkB family
AW59_RS12495	COG3001	Fructosamine kinase
AW59_RS12505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW59_RS12510	COG1988	membrane-bound metal-dependent
AW59_RS12515	COG1823	symporter activity
AW59_RS12525	COG0753	catalase activity
AW59_RS12535	COG1486	melibiose metabolic process
AW59_RS12540	COG2169	Transcriptional regulator
AW59_RS12540	COG1917	Cupin 2, conserved barrel domain protein
AW59_RS12545	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW59_RS12550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW59_RS12555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW59_RS12560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AW59_RS12575	COG3678	ATP-independent chaperone mediated protein folding
AW59_RS12610	COG0494	nUDIX hydrolase
AW59_RS12625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW59_RS12635	COG0778	Nitroreductase
AW59_RS12640	COG0616	signal peptide processing
AW59_RS12645	COG0252	asparaginase activity
AW59_RS12650	COG1335	isochorismatase
AW59_RS12655	COG3139	Protein of unknown function (DUF1315)
AW59_RS12675	COG0656	L-ascorbic acid biosynthetic process
AW59_RS12680	COG0641	radical SAM
AW59_RS12685	COG3713	MltA-interacting MipA family protein
AW59_RS12690	COG2766	serine protein kinase
AW59_RS12705	COG2199	diguanylate cyclase activity
AW59_RS12710	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW59_RS12725	COG2207	Transcriptional regulator
AW59_RS12730	COG2807	transmembrane transport
AW59_RS12735	COG3189	MarR family transcriptional regulator
AW59_RS12745	COG3042	response to heat
AW59_RS12750	COG2261	transglycosylase associated protein
AW59_RS12770	COG3615	Tellurite resistance protein tehB
AW59_RS12780	COG1605	Chorismate mutase
AW59_RS12795	COG0789	Transcriptional regulator
AW59_RS12810	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW59_RS12825	COG0668	transmembrane transport
AW59_RS12830	COG1124	(ABC) transporter
AW59_RS12850	COG0747	negative chemotaxis
AW59_RS12860	COG3038	cytochrome b561
AW59_RS12875	COG0071	Belongs to the small heat shock protein (HSP20) family
AW59_RS12965	COG2135	peptidase activity
AW59_RS13000	COG5301	cellulose 1,4-beta-cellobiosidase activity
AW59_RS13105	COG4220	transposase activity
AW59_RS13120	COG3179	chitinase
AW59_RS13185	COG1484	DNA-dependent DNA replication
AW59_RS13190	COG3756	Protein conserved in bacteria
AW59_RS13205	COG1396	sequence-specific DNA binding
AW59_RS13235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW59_RS13240	COG3723	Recombinational DNA repair protein, rece pathway
AW59_RS13265	COG0582	viral genome integration into host DNA
AW59_RS13270	COG0538	isocitrate dehydrogenase activity
AW59_RS13300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AW59_RS13315	COG2850	peptidyl-arginine hydroxylation
AW59_RS13345	COG1177	transmembrane transport
AW59_RS13365	COG4591	ABC-type transport system involved in lipoprotein release permease component
AW59_RS13370	COG1136	(ABC) transporter
AW59_RS13375	COG4591	ABC-type transport system involved in lipoprotein release permease component
AW59_RS13380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AW59_RS13385	COG1388	LysM domain
AW59_RS13385	COG1376	ErfK ybiS ycfS ynhG family protein
AW59_RS13395	COG1309	transcriptional regulator
AW59_RS13400	COG3134	Outer membrane lipoprotein
AW59_RS13405	COG1252	NADH dehydrogenase
AW59_RS13430	COG5633	Lipoprotein
AW59_RS13435	COG0537	adenosine 5'-monophosphoramidase activity
AW59_RS13440	COG4773	Receptor
AW59_RS13450	COG0084	hydrolase, TatD family'
AW59_RS13455	COG0470	DNA polymerase III
AW59_RS13465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW59_RS13470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW59_RS13475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW59_RS13540	COG1530	ribonuclease E activity
AW59_RS13630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW59_RS13640	COG2999	glutathione oxidoreductase activity
AW59_RS13675	COG3038	cytochrome b561
AW59_RS13690	COG1560	Kdo2-lipid A biosynthetic process
AW59_RS13705	COG5645	(Lipo)protein
AW59_RS13725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW59_RS13780	COG3381	protein complex oligomerization
AW59_RS13805	COG0673	inositol 2-dehydrogenase activity
AW59_RS13810	COG2814	Major facilitator Superfamily
AW59_RS13830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW59_RS13835	COG1737	Transcriptional regulator
AW59_RS13840	COG1702	phosphate starvation-inducible protein PhoH
AW59_RS13865	COG1309	transcriptional regulator
AW59_RS13870	COG3729	General stress protein
AW59_RS13890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW59_RS13895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW59_RS13895	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AW59_RS13900	COG4232	protein-disulfide reductase activity
AW59_RS13945	COG3971	2-oxopent-4-enoate hydratase activity
AW59_RS13955	COG3384	dioxygenase
AW59_RS13960	COG1012	belongs to the aldehyde dehydrogenase family
AW59_RS13970	COG1846	Transcriptional regulator
AW59_RS13975	COG2368	4-hydroxyphenylacetate
AW59_RS13990	COG0745	RESPONSE REGULATOR receiver
AW59_RS13995	COG2205	protein histidine kinase activity
AW59_RS14045	COG0670	Belongs to the BI1 family
AW59_RS14065	COG1881	PFAM PEBP family protein
AW59_RS14080	COG1832	CoA-binding protein
AW59_RS14095	COG0210	DNA helicase
AW59_RS14100	COG3304	Inner membrane component domain
AW59_RS14105	COG1289	transmembrane transporter activity
AW59_RS14110	COG3070	regulator of competence-specific genes
AW59_RS14130	COG1067	ATP-dependent peptidase activity
AW59_RS14140	COG3130	regulation of translation
AW59_RS14145	COG3009	Protein conserved in bacteria
AW59_RS14150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AW59_RS14150	COG3008	intermembrane lipid transfer
AW59_RS14155	COG2995	paraquat-inducible protein a
AW59_RS14160	COG0488	(ABC) transporter
AW59_RS14170	COG0633	Ferredoxin
AW59_RS14170	COG3217	Mosc domain protein beta barrel domain protein
AW59_RS14185	COG0308	aminopeptidase N
AW59_RS14195	COG1115	amino acid carrier protein
AW59_RS14205	COG1522	sequence-specific DNA binding
AW59_RS14210	COG0017	Asparaginyl-tRNA synthetase
AW59_RS14215	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AW59_RS14225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW59_RS14230	COG3108	Peptidase M15
AW59_RS14235	COG2989	Protein conserved in bacteria
AW59_RS14245	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AW59_RS14255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW59_RS14260	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AW59_RS14265	COG3173	Aminoglycoside phosphotransferase
AW59_RS14280	COG3214	Protein conserved in bacteria
AW59_RS14295	COG0658	competence protein
AW59_RS14295	COG2333	competence protein COMEC
AW59_RS14305	COG0539	negative regulation of cytoplasmic translation
AW59_RS14315	COG0501	Belongs to the peptidase M48B family
AW59_RS14330	COG2323	membrane
AW59_RS14335	COG1944	ATP diphosphatase activity
AW59_RS14340	COG2116	formate transmembrane transporter activity
AW59_RS14345	COG1882	Formate acetyltransferase
AW59_RS14360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AW59_RS14365	COG0531	amino acid
AW59_RS14380	COG3302	dmso reductase anchor subunit
AW59_RS14385	COG0437	4 iron, 4 sulfur cluster binding
AW59_RS14390	COG0243	molybdopterin cofactor binding
AW59_RS14400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AW59_RS14420	COG0492	ferredoxin-NADP+ reductase activity
AW59_RS14425	COG4988	ABC transporter
AW59_RS14430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AW59_RS14450	COG0583	DNA-binding transcription factor activity
AW59_RS14460	COG1335	isochorismatase
AW59_RS14495	COG4916	TIR domain
AW59_RS14585	COG0582	viral genome integration into host DNA
AW59_RS14605	COG0542	response to heat
AW59_RS14615	COG1278	Cold shock
AW59_RS14620	COG0577	efflux transmembrane transporter activity
AW59_RS14620	COG1136	(ABC) transporter
AW59_RS14625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW59_RS14630	COG2990	Protein conserved in bacteria
AW59_RS14635	COG3593	DNA synthesis involved in DNA repair
AW59_RS14640	COG2431	L-lysine efflux transmembrane transporter activity
AW59_RS14650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW59_RS14655	COG0028	Belongs to the TPP enzyme family
AW59_RS14660	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AW59_RS14665	COG0702	epimerase
AW59_RS14670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW59_RS14675	COG3023	N-Acetylmuramoyl-L-alanine amidase
AW59_RS14690	COG1126	abc transporter atp-binding protein
AW59_RS14695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW59_RS14700	COG4215	(ABC) transporter
AW59_RS14705	COG4160	amino acid transport
AW59_RS14710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW59_RS14740	COG1177	transmembrane transport
AW59_RS14745	COG1176	ABC-type spermidine putrescine transport system, permease component I
AW59_RS14750	COG3842	ATPase activity
AW59_RS14755	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AW59_RS14795	COG3226	Transcriptional regulator
AW59_RS14800	COG0738	Major facilitator superfamily
AW59_RS14805	COG0561	phosphatase activity
AW59_RS14810	COG2814	Major facilitator Superfamily
AW59_RS14815	COG0671	phosphoesterase, PA-phosphatase related
AW59_RS14820	COG1349	DNA-binding transcription factor activity
AW59_RS14825	COG1686	Belongs to the peptidase S11 family
AW59_RS14830	COG0625	glutathione transferase activity
AW59_RS14835	COG2133	pyrroloquinoline quinone binding
AW59_RS14840	COG2610	gluconate transmembrane transporter activity
AW59_RS14845	COG0583	DNA-binding transcription factor activity
AW59_RS14855	COG1960	acyl-CoA dehydrogenase activity
AW59_RS14875	COG2301	Belongs to the HpcH HpaI aldolase family
AW59_RS14900	COG0747	negative chemotaxis
AW59_RS14925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AW59_RS14930	COG1882	Formate acetyltransferase
AW59_RS14935	COG0561	phosphatase activity
AW59_RS14955	COG0488	(ABC) transporter
AW59_RS14960	COG1376	ErfK ybiS ycfS ynhG family protein
AW59_RS14965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW59_RS14975	COG2194	sulfuric ester hydrolase activity
AW59_RS14980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AW59_RS14995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW59_RS15000	COG0765	amino acid transport
AW59_RS15005	COG1126	abc transporter atp-binding protein
AW59_RS15010	COG0668	transmembrane transport
AW59_RS15020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW59_RS15035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AW59_RS15045	COG0513	Belongs to the DEAD box helicase family
AW59_RS15050	COG1309	transcriptional regulator
AW59_RS15060	COG1131	(ABC) transporter
AW59_RS15065	COG0842	Transport permease protein
AW59_RS15070	COG0842	Transport permease protein
AW59_RS15080	COG3568	Endonuclease Exonuclease Phosphatase
AW59_RS15085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW59_RS15090	COG0392	lysyltransferase activity
AW59_RS15110	COG0670	Belongs to the BI1 family
AW59_RS15120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AW59_RS15130	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW59_RS15160	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AW59_RS15185	COG1881	PFAM PEBP family protein
AW59_RS15215	COG4677	pectinesterase activity
AW59_RS15225	COG0561	phosphatase activity
AW59_RS15235	COG4149	molybdate abc transporter
AW59_RS15240	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW59_RS15250	COG2005	Transcriptional regulator
AW59_RS15250	COG3585	molybdate ion transport
AW59_RS15255	COG1119	ATPase activity
AW59_RS15280	COG2017	converts alpha-aldose to the beta-anomer
AW59_RS15290	COG1120	ATPase activity
AW59_RS15295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW59_RS15305	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AW59_RS15320	COG0471	metal ion transport
AW59_RS15320	COG0490	domain, Protein
AW59_RS15325	COG0583	DNA-binding transcription factor activity
AW59_RS15330	COG0583	DNA-binding transcription factor activity
AW59_RS15340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AW59_RS15340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AW59_RS15345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AW59_RS15355	COG1230	cation diffusion facilitator family transporter
AW59_RS15400	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AW59_RS15405	COG2885	chlorophyll binding
AW59_RS15415	COG3064	Membrane
AW59_RS15420	COG0848	biopolymer transport protein
AW59_RS15425	COG0811	peptide transport
AW59_RS15430	COG0824	Thioesterase
AW59_RS15435	COG3790	cyd operon protein YbgE
AW59_RS15440	COG4890	Cyd operon protein YbgT
AW59_RS15445	COG1294	oxidase, subunit
AW59_RS15450	COG1271	oxidase subunit
AW59_RS15460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW59_RS15470	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW59_RS15475	COG0567	Dehydrogenase, E1 component
AW59_RS15490	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AW59_RS15510	COG3180	Ammonia monooxygenase
AW59_RS15535	COG1216	Glycosyl transferase, family 2
AW59_RS15575	COG0582	viral genome integration into host DNA
AW59_RS15590	COG1984	allophanate hydrolase subunit 2
AW59_RS15595	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AW59_RS15640	COG2205	protein histidine kinase activity
AW59_RS15645	COG0745	RESPONSE REGULATOR receiver
AW59_RS15655	COG1982	Orn Lys Arg decarboxylase major
AW59_RS15660	COG0531	amino acid
AW59_RS15680	COG0596	Alpha beta hydrolase
AW59_RS15695	COG0735	belongs to the Fur family
AW59_RS15700	COG0583	DNA-binding transcription factor activity
AW59_RS15705	COG1053	succinate dehydrogenase
AW59_RS15745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW59_RS15750	COG1940	carbohydrate kinase activity
AW59_RS15750	COG1846	Transcriptional regulator
AW59_RS15755	COG0647	UMP catabolic process
AW59_RS15760	COG0367	asparagine synthase
AW59_RS15805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW59_RS15815	COG1702	phosphate starvation-inducible protein PhoH
AW59_RS15840	COG0765	amino acid transport
AW59_RS15845	COG0765	amino acid transport
AW59_RS15850	COG1126	abc transporter atp-binding protein
AW59_RS15865	COG0443	Heat shock 70 kDa protein
AW59_RS15870	COG2214	Heat shock protein DnaJ domain protein
AW59_RS15880	COG2214	Heat shock protein DnaJ domain protein
AW59_RS15895	COG2888	peptidyl-tyrosine sulfation
AW59_RS15900	COG3290	protein histidine kinase activity
AW59_RS15900	COG3829	transcription factor binding
AW59_RS15930	COG1466	dna polymerase III delta subunit
AW59_RS15955	COG0799	negative regulation of ribosome biogenesis
AW59_RS15965	COG0768	penicillin binding
AW59_RS15970	COG0772	Belongs to the SEDS family
AW59_RS15980	COG1686	Belongs to the peptidase S11 family
AW59_RS15995	COG0583	DNA-binding transcription factor activity
AW59_RS16010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW59_RS16030	COG3069	C4-dicarboxylate transmembrane transporter activity
AW59_RS16035	COG4565	transcriptional regulatory protein
AW59_RS16040	COG3290	protein histidine kinase activity
AW59_RS16045	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AW59_RS16055	COG2301	Belongs to the HpcH HpaI aldolase family
AW59_RS16060	COG3051	citrate lyase alpha subunit
AW59_RS16075	COG0471	metal ion transport
AW59_RS16080	COG3719	Belongs to the RNase T2 family
AW59_RS16085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AW59_RS16090	COG1063	alcohol dehydrogenase
AW59_RS16110	COG0243	molybdopterin cofactor binding
AW59_RS16130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW59_RS16135	COG0583	DNA-binding transcription factor activity
AW59_RS16140	COG3969	phosphoadenosine phosphosulfate
AW59_RS16145	COG1475	DNA binding
AW59_RS16150	COG0436	Aminotransferase
AW59_RS16155	COG0371	Dehydrogenase
AW59_RS16160	COG2879	small protein
AW59_RS16165	COG1966	Carbon starvation protein
AW59_RS16175	COG1028	Short-chain dehydrogenase reductase Sdr
AW59_RS16180	COG3433	isochorismatase activity
AW59_RS16180	COG1535	isochorismatase
AW59_RS16185	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW59_RS16190	COG1169	isochorismate synthase
AW59_RS16195	COG4592	Periplasmic binding protein
AW59_RS16205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW59_RS16210	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW59_RS16215	COG1120	ATPase activity
AW59_RS16220	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AW59_RS16225	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AW59_RS16225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW59_RS16230	COG3251	PFAM MbtH domain protein
AW59_RS16235	COG2382	esterase
AW59_RS16240	COG4771	TonB-dependent receptor
AW59_RS16245	COG2977	Belongs to the P-Pant transferase superfamily
AW59_RS16270	COG2315	Protein conserved in bacteria
AW59_RS16295	COG3716	PTS system mannose fructose sorbose family IID component
AW59_RS16305	COG2222	sugar isomerase
AW59_RS16310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW59_RS16310	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AW59_RS16320	COG0668	transmembrane transport
AW59_RS16325	COG1113	amino acid transport
AW59_RS16335	COG3059	membrane
AW59_RS16345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW59_RS16350	COG2207	Transcriptional regulator
AW59_RS16355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AW59_RS16355	COG2755	lipolytic protein G-D-S-L family
AW59_RS16460	COG3772	lysozyme
AW59_RS16515	COG0305	Participates in initiation and elongation during chromosome replication
AW59_RS16570	COG4712	double-strand break repair protein
AW59_RS16625	COG0582	viral genome integration into host DNA
AW59_RS16690	COG2501	S4 domain
AW59_RS16695	COG1988	membrane-bound metal-dependent
AW59_RS16715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW59_RS16725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AW59_RS16730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AW59_RS16735	COG0549	Belongs to the carbamate kinase family
AW59_RS16745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW59_RS16750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW59_RS16755	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AW59_RS16760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW59_RS16765	COG3257	ureidoglycine aminohydrolase activity
AW59_RS16770	COG1929	Belongs to the glycerate kinase type-1 family
AW59_RS16775	COG2233	PERMEase
AW59_RS16785	COG1953	Uracil, thiamine, allantoin
AW59_RS16795	COG2084	Dehydrogenase
AW59_RS16800	COG3622	Belongs to the hyi family
AW59_RS16805	COG3960	tartronate-semialdehyde synthase activity
AW59_RS16840	COG1464	Belongs to the NlpA lipoprotein family
AW59_RS16850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AW59_RS16855	COG4181	ATPase activity
AW59_RS16860	COG2755	lipolytic protein G-D-S-L family
AW59_RS16865	COG0300	oxidoreductase activity
AW59_RS16870	COG3118	belongs to the thioredoxin family
AW59_RS16875	COG0390	transport system, permease component
AW59_RS16880	COG4619	ABC transporter
AW59_RS16885	COG0330	HflC and HflK could
AW59_RS16890	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW59_RS16900	COG2217	Heavy metal translocating P-type atpase
AW59_RS16910	COG3735	TraB family
AW59_RS16925	COG2223	nitrite transmembrane transporter activity
AW59_RS16930	COG4651	solute:proton antiporter activity
AW59_RS16930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW59_RS16935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW59_RS16980	COG2832	Protein of unknown function (DUF454)
AW59_RS16985	COG3923	Primosomal replication protein n
AW59_RS16995	COG5464	transposase or invertase
AW59_RS17000	COG1196	nuclear chromosome segregation
AW59_RS17000	COG3264	Mechanosensitive ion channel
AW59_RS17005	COG1309	transcriptional regulator
AW59_RS17010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW59_RS17015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW59_RS17030	COG0110	maltose O-acetyltransferase activity
AW59_RS17050	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AW59_RS17060	COG3695	enzyme binding
AW59_RS17065	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AW59_RS17070	COG1946	Acyl-CoA thioesterase
AW59_RS17075	COG0004	ammonium transporteR
AW59_RS17080	COG0347	Belongs to the P(II) protein family
AW59_RS17085	COG1132	(ABC) transporter
AW59_RS17090	COG1132	(ABC) transporter
AW59_RS17095	COG1522	sequence-specific DNA binding
AW59_RS17110	COG4533	DNA binding
AW59_RS17120	COG0824	Thioesterase
AW59_RS17125	COG1555	photosystem II stabilization
AW59_RS17130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW59_RS17140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AW59_RS17160	COG0271	Belongs to the BolA IbaG family
AW59_RS17165	COG3056	Lipoprotein
AW59_RS17170	COG2223	nitrite transmembrane transporter activity
AW59_RS17175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW59_RS17180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW59_RS17185	COG1845	cytochrome c oxidase, subunit III
AW59_RS17190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AW59_RS17210	COG2814	Major facilitator Superfamily
AW59_RS17240	COG2188	Transcriptional regulator
AW59_RS17275	COG0142	geranyltranstransferase activity
AW59_RS17285	COG0667	Aldo Keto reductase
AW59_RS17290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW59_RS17310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW59_RS17310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW59_RS17320	COG4238	major outer membrane lipoprotein
AW59_RS17350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW59_RS17360	COG1862	Preprotein translocase
AW59_RS17380	COG0450	alkyl hydroperoxide reductase
AW59_RS17385	COG0366	Alpha amylase catalytic
AW59_RS17400	COG5002	protein histidine kinase activity
AW59_RS17415	COG0420	3'-5' exonuclease activity
AW59_RS17420	COG0419	ATPase involved in DNA repair
AW59_RS17425	COG2814	Major facilitator Superfamily
AW59_RS17430	COG1940	carbohydrate kinase activity
AW59_RS17445	COG4126	flavin adenine dinucleotide binding
AW59_RS17465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW59_RS17470	COG3706	GGDEF domain
AW59_RS17515	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AW59_RS17520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW59_RS17535	COG0113	porphobilinogen synthase activity
AW59_RS17570	COG1280	lysine exporter protein (LysE YggA)
AW59_RS17590	COG1294	oxidase, subunit
AW59_RS17595	COG1271	oxidase subunit
AW59_RS17615	COG2814	Major facilitator Superfamily
AW59_RS17630	COG0789	Transcriptional regulator
AW59_RS17685	COG2200	EAL domain
AW59_RS17700	COG3539	Fimbrial protein
AW59_RS17705	COG3121	Chaperone
AW59_RS17710	COG3188	usher protein
AW59_RS17745	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW59_RS17760	COG2814	Major facilitator Superfamily
AW59_RS17780	COG2801	Transposase and inactivated derivatives
AW59_RS17820	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW59_RS17825	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AW59_RS17830	COG1690	Belongs to the RtcB family
AW59_RS17840	COG3034	peptidoglycan biosynthetic process
AW59_RS17845	COG0121	glutamine amidotransferase
AW59_RS17860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW59_RS17960	COG3209	COG3209 Rhs family protein
AW59_RS18110	COG2226	methyltransferase
AW59_RS18120	COG1388	LysM domain
AW59_RS18120	COG0741	lytic transglycosylase activity
AW59_RS18125	COG2226	methyltransferase
AW59_RS18135	COG2814	Major facilitator Superfamily
AW59_RS18140	COG0583	DNA-binding transcription factor activity
AW59_RS18180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AW59_RS18205	COG1720	tRNA m6t6A37 methyltransferase activity
AW59_RS18215	COG3015	lipoprotein NlpE involved in copper resistance
AW59_RS18220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AW59_RS18235	COG4568	rho-dependent transcription termination
AW59_RS18245	COG0346	lactoylglutathione lyase activity
AW59_RS18250	COG1982	Orn Lys Arg decarboxylase major
AW59_RS18310	COG0575	Belongs to the CDS family
AW59_RS18360	COG0477	Major facilitator Superfamily
AW59_RS18370	COG3835	regulator
AW59_RS18395	COG2860	membrane
AW59_RS18405	COG0038	chloride channel
AW59_RS18410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AW59_RS18425	COG3539	Fimbrial protein
AW59_RS18430	COG3539	Fimbrial protein
AW59_RS18435	COG3121	Chaperone
AW59_RS18440	COG3188	usher protein
AW59_RS18455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW59_RS18460	COG1120	ATPase activity
AW59_RS18465	COG4774	siderophore transport
AW59_RS18470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW59_RS18475	COG1643	Atp-dependent helicase
AW59_RS18480	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AW59_RS18505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AW59_RS18525	COG0726	polysaccharide deacetylase
AW59_RS18530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS18550	COG3539	Fimbrial protein
AW59_RS18555	COG0842	Transport permease protein
AW59_RS18560	COG1131	(ABC) transporter
AW59_RS18565	COG0288	reversible hydration of carbon dioxide
AW59_RS18575	COG4993	Dehydrogenase
AW59_RS18600	COG1349	DNA-binding transcription factor activity
AW59_RS18640	COG3064	Membrane
AW59_RS18655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW59_RS18660	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW59_RS18665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AW59_RS18680	COG2211	Major facilitator Superfamily
AW59_RS18685	COG3940	Belongs to the glycosyl hydrolase 43 family
AW59_RS18690	COG3725	Membrane protein required for beta-lactamase induction
AW59_RS18705	COG4969	Belongs to the N-Me-Phe pilin family
AW59_RS18710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW59_RS18715	COG1459	type II secretion system
AW59_RS18745	COG0494	nUDIX hydrolase
AW59_RS18765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AW59_RS18770	COG0849	cell division
AW59_RS18795	COG0772	Belongs to the SEDS family
AW59_RS18810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW59_RS18820	COG0768	penicillin binding
AW59_RS18915	COG0586	Pfam SNARE associated Golgi protein
AW59_RS18950	COG0417	DNA replication proofreading
AW59_RS18980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AW59_RS19020	COG3119	arylsulfatase activity
AW59_RS19045	COG2271	Major facilitator Superfamily
AW59_RS19050	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AW59_RS19055	COG0644	oxidoreductase
AW59_RS19165	COG0511	ligase activity, forming carbon-carbon bonds
AW59_RS19165	COG5016	pyruvate
AW59_RS19170	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AW59_RS19200	COG1047	Peptidyl-prolyl cis-trans
AW59_RS19215	COG0196	riboflavin kinase activity
AW59_RS19240	COG0583	DNA-binding transcription factor activity
AW59_RS19260	COG0641	radical SAM
AW59_RS19265	COG3119	arylsulfatase activity
AW59_RS19275	COG0737	Belongs to the 5'-nucleotidase family
AW59_RS19290	COG0583	DNA-binding transcription factor activity
AW59_RS19310	COG3121	Chaperone
AW59_RS19315	COG3539	Fimbrial protein
AW59_RS19330	COG3188	usher protein
AW59_RS19395	COG4735	regulation of single-species biofilm formation
AW59_RS19400	COG1584	GPR1 FUN34 yaaH family protein
AW59_RS19405	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW59_RS19415	COG1115	amino acid carrier protein
AW59_RS19425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AW59_RS19435	COG0460	homoserine dehydrogenase
AW59_RS19435	COG0527	aspartate kinase activity
AW59_RS19445	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AW59_RS19455	COG0745	RESPONSE REGULATOR receiver
AW59_RS19475	COG3121	Chaperone
AW59_RS19495	COG4452	Inner membrane protein CreD
AW59_RS19500	COG2205	protein histidine kinase activity
AW59_RS19505	COG0745	RESPONSE REGULATOR receiver
AW59_RS19510	COG3045	CreA protein
AW59_RS19515	COG2207	Transcriptional regulator
AW59_RS19515	COG3708	Transcriptional regulator
AW59_RS19540	COG0488	(ABC) transporter
AW59_RS19555	COG0560	Phosphoserine phosphatase
AW59_RS19560	COG3726	membrane protein affecting hemolysin expression
AW59_RS19575	COG3539	Fimbrial protein
AW59_RS19580	COG3121	Chaperone
AW59_RS19585	COG3188	usher protein
AW59_RS19615	COG1328	CTP reductase activity
AW59_RS19620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AW59_RS19625	COG0084	hydrolase, TatD family'
AW59_RS19630	COG4667	esterase of the alpha-beta hydrolase superfamily
AW59_RS19640	COG2823	Periplasmic or secreted lipoprotein
AW59_RS19650	COG1011	Hydrolase
AW59_RS19660	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AW59_RS19690	COG3706	GGDEF domain
AW59_RS19695	COG4114	ferric iron reductase
AW59_RS19700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW59_RS19705	COG2197	response regulator
AW59_RS19710	COG2197	response regulator
AW59_RS19715	COG2966	Psort location CytoplasmicMembrane, score
AW59_RS19730	COG1484	DNA-dependent DNA replication
AW59_RS19750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AW59_RS19755	COG3716	PTS system mannose fructose sorbose family IID component
AW59_RS19760	COG3715	PTS system
AW59_RS19765	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW59_RS19780	COG0840	transmembrane signaling receptor activity
AW59_RS19785	COG1966	Carbon starvation protein
AW59_RS19790	COG2879	small protein
AW59_RS19795	COG0523	cobalamin synthesis protein
AW59_RS19810	COG1715	Restriction endonuclease
AW59_RS19815	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AW59_RS19850	COG1012	belongs to the aldehyde dehydrogenase family
AW59_RS19855	COG5464	transposase or invertase
AW59_RS19865	COG2733	membrane
AW59_RS19870	COG0477	Major facilitator Superfamily
AW59_RS19880	COG3366	ferrous iron transmembrane transporter activity
AW59_RS19885	COG0700	Nucleoside recognition
AW59_RS19890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW59_RS19895	COG0583	DNA-binding transcription factor activity
AW59_RS19920	COG2186	Transcriptional regulator
AW59_RS19925	COG0412	Dienelactone hydrolase
AW59_RS19955	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AW59_RS20030	COG0582	viral genome integration into host DNA
AW59_RS20040	COG1064	alcohol dehydrogenase
AW59_RS20045	COG3265	gluconokinase activity
AW59_RS20050	COG1063	alcohol dehydrogenase
AW59_RS20055	COG1028	Short-chain dehydrogenase reductase Sdr
AW59_RS20060	COG2610	gluconate transmembrane transporter activity
AW59_RS20065	COG1609	Transcriptional regulator
AW59_RS20070	COG0795	lipopolysaccharide-transporting ATPase activity
AW59_RS20075	COG0795	lipopolysaccharide-transporting ATPase activity
AW59_RS20090	COG2927	DNA polymerase III (CHI subunit)
AW59_RS20130	COG2731	YhcH YjgK YiaL family protein
AW59_RS20150	COG1288	antiporter activity
AW59_RS20155	COG1438	arginine binding
AW59_RS20195	COG1263	PTS System
AW59_RS20195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW59_RS20200	COG0366	Alpha amylase catalytic
AW59_RS20220	COG2026	Addiction module toxin, RelE StbE family
AW59_RS20225	COG3077	Addiction module antitoxin, RelB DinJ family
AW59_RS20230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW59_RS20230	COG3711	transcriptional antiterminator
AW59_RS20245	COG3964	amidohydrolase
AW59_RS20280	COG0312	modulator of DNA gyrase
AW59_RS20290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AW59_RS20305	COG3964	amidohydrolase
AW59_RS20310	COG2271	Major facilitator Superfamily
AW59_RS20315	COG2105	PFAM AIG2 family protein
AW59_RS20335	COG1253	flavin adenine dinucleotide binding
AW59_RS20345	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AW59_RS20360	COG1733	regulation of RNA biosynthetic process
AW59_RS20365	COG0702	epimerase
AW59_RS20370	COG0697	spore germination
AW59_RS20380	COG1113	amino acid transport
AW59_RS20385	COG0545	Peptidyl-prolyl cis-trans isomerase
AW59_RS20390	COG3061	Opacity-associated protein A
AW59_RS20405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AW59_RS20455	COG3037	sugar-specific permease SgaT UlaA
AW59_RS20470	COG1073	alpha beta
AW59_RS20475	COG3650	response to hydrogen peroxide
AW59_RS20485	COG1960	acyl-CoA dehydrogenase activity
AW59_RS20490	COG0754	glutathionylspermidine amidase activity
AW59_RS20495	COG5463	Belongs to the UPF0441 family
AW59_RS20500	COG3766	membrane
AW59_RS20515	COG1842	Phage shock protein A
AW59_RS20520	COG3789	protein conserved in bacteria
AW59_RS20530	COG0557	exoribonuclease II activity
AW59_RS20545	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AW59_RS20550	COG0330	HflC and HflK could
AW59_RS20555	COG0330	HflC and HflK could
AW59_RS20560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW59_RS20585	COG0802	atpase or kinase
AW59_RS20590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AW59_RS20590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AW59_RS20615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW59_RS20635	COG3264	Mechanosensitive ion channel
AW59_RS20635	COG1511	domain protein
AW59_RS20655	COG1053	succinate dehydrogenase
AW59_RS20660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AW59_RS20690	COG5510	response to toxic substance
AW59_RS20730	COG0531	amino acid
AW59_RS20735	COG3030	protein affecting phage T7 exclusion by the F plasmid
AW59_RS20745	COG1027	Aspartate ammonia-lyase
AW59_RS20750	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW59_RS20765	COG1309	transcriptional regulator
AW59_RS20775	COG0671	phosphoesterase, PA-phosphatase related
AW59_RS20835	COG2801	Transposase and inactivated derivatives
AW59_RS20860	COG2197	response regulator
AW59_RS20880	COG3381	protein complex oligomerization
AW59_RS20885	COG3302	dmso reductase anchor subunit
AW59_RS20890	COG0437	4 iron, 4 sulfur cluster binding
AW59_RS20895	COG0243	molybdopterin cofactor binding
AW59_RS20900	COG3290	protein histidine kinase activity
AW59_RS20905	COG4565	transcriptional regulatory protein
AW59_RS20915	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW59_RS20920	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AW59_RS20920	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AW59_RS20935	COG2169	Transcriptional regulator
AW59_RS20940	COG1982	Orn Lys Arg decarboxylase major
AW59_RS20945	COG2207	Transcriptional regulator
AW59_RS20950	COG0531	amino acid
AW59_RS20975	COG2824	Alkylphosphonate utilization operon protein PhnA
AW59_RS20980	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AW59_RS20995	COG3383	formate dehydrogenase (NAD+) activity
AW59_RS21000	COG3383	formate dehydrogenase (NAD+) activity
AW59_RS21005	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AW59_RS21010	COG1301	dicarboxylic acid transport
AW59_RS21015	COG4235	cytochrome complex assembly
AW59_RS21020	COG3088	subunit of a heme lyase
AW59_RS21025	COG1138	Cytochrome C-type biogenesis protein
AW59_RS21030	COG3301	Polysulphide reductase, NrfD
AW59_RS21035	COG0437	4 iron, 4 sulfur cluster binding
AW59_RS21040	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AW59_RS21055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW59_RS21060	COG3162	membrane
AW59_RS21070	COG1346	cytolysis
AW59_RS21075	COG1380	Effector of murein hydrolase LrgA
AW59_RS21080	COG0583	DNA-binding transcription factor activity
AW59_RS21085	COG0025	NhaP-type Na H and K H
AW59_RS21090	COG2252	PERMEase
AW59_RS21110	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AW59_RS21175	COG2315	Protein conserved in bacteria
AW59_RS21225	COG0735	belongs to the Fur family
AW59_RS21240	COG0534	Mate efflux family protein
AW59_RS21250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AW59_RS21295	COG3833	ABC-type maltose transport systems, permease component
AW59_RS21305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AW59_RS21330	COG0527	aspartate kinase activity
AW59_RS21405	COG2246	polysaccharide biosynthetic process
AW59_RS21435	COG5301	cellulose 1,4-beta-cellobiosidase activity
AW59_RS21440	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AW59_RS21455	COG0561	phosphatase activity
AW59_RS21460	COG1349	DNA-binding transcription factor activity
AW59_RS21475	COG3122	Protein conserved in bacteria
AW59_RS21520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AW59_RS21560	COG0151	Belongs to the GarS family
AW59_RS21625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW59_RS21630	COG2104	thiamine diphosphate biosynthetic process
AW59_RS21685	COG0250	Participates in transcription elongation, termination and antitermination
AW59_RS21795	COG0583	DNA-binding transcription factor activity
AW59_RS21830	COG2207	Transcriptional regulator
AW59_RS21840	COG0371	Dehydrogenase
AW59_RS21845	COG3738	Protein conserved in bacteria
AW59_RS21860	COG0737	Belongs to the 5'-nucleotidase family
AW59_RS21875	COG0668	transmembrane transport
AW59_RS21880	COG0460	homoserine dehydrogenase
AW59_RS21880	COG0527	aspartate kinase activity
AW59_RS21885	COG0626	cystathionine gamma-synthase activity
AW59_RS21910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW59_RS21915	COG1609	Transcriptional regulator
AW59_RS21920	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AW59_RS21935	COG1575	Belongs to the MenA family. Type 1 subfamily
AW59_RS21950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW59_RS21960	COG1494	fructose-1,6-bisphosphatase
AW59_RS21970	COG3152	Membrane
AW59_RS22025	COG1070	Carbohydrate kinase
AW59_RS22040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW59_RS22050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW59_RS22055	COG2211	Major facilitator Superfamily
AW59_RS22080	COG3678	ATP-independent chaperone mediated protein folding
AW59_RS22085	COG0745	RESPONSE REGULATOR receiver
AW59_RS22090	COG2205	protein histidine kinase activity
AW59_RS22100	COG2258	MOSC domain
AW59_RS22105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW59_RS22115	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AW59_RS22165	COG1454	alcohol dehydrogenase
AW59_RS22180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AW59_RS22205	COG0243	molybdopterin cofactor binding
AW59_RS22205	COG3383	formate dehydrogenase (NAD+) activity
AW59_RS22210	COG0243	molybdopterin cofactor binding
AW59_RS22210	COG3383	formate dehydrogenase (NAD+) activity
AW59_RS22215	COG0437	4 iron, 4 sulfur cluster binding
AW59_RS22220	COG2864	formate dehydrogenase
AW59_RS22235	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AW59_RS22245	COG4680	protein conserved in bacteria
AW59_RS22250	COG5499	transcription regulator containing HTH domain
AW59_RS22255	COG0456	acetyltransferase
AW59_RS22270	COG1011	Hydrolase
AW59_RS22275	COG1349	DNA-binding transcription factor activity
AW59_RS22280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW59_RS22300	COG2017	converts alpha-aldose to the beta-anomer
AW59_RS22305	COG1501	Belongs to the glycosyl hydrolase 31 family
AW59_RS22380	COG0204	Acyl-transferase
AW59_RS22395	COG3084	Protein conserved in bacteria
AW59_RS22400	COG0746	molybdenum cofactor guanylyltransferase activity
AW59_RS22405	COG1763	Mo-molybdopterin cofactor biosynthetic process
AW59_RS22445	COG1739	Uncharacterized protein family UPF0029
AW59_RS22490	COG0805	protein transport
AW59_RS22535	COG0641	radical SAM
AW59_RS22555	COG0561	phosphatase activity
AW59_RS22560	COG2267	carboxylic ester hydrolase activity
AW59_RS22570	COG1280	lysine exporter protein (LysE YggA)
AW59_RS22615	COG1011	Hydrolase
AW59_RS22680	COG2959	enzyme of heme biosynthesis
AW59_RS22685	COG3071	HemY protein
AW59_RS22730	COG2244	polysaccharide biosynthetic process
AW59_RS22735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW59_RS22740	COG0456	acetyltransferase
AW59_RS22745	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AW59_RS22750	COG1088	dTDP-glucose 4,6-dehydratase activity
AW59_RS22755	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AW59_RS22780	COG3118	belongs to the thioredoxin family
AW59_RS22845	COG3978	acetolactate synthase activity
AW59_RS22905	COG2186	Transcriptional regulator
AW59_RS22910	COG0477	Major facilitator Superfamily
AW59_RS22915	COG1609	Transcriptional regulator
AW59_RS22920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW59_RS22930	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW59_RS22965	COG1522	sequence-specific DNA binding
AW59_RS22970	COG0716	FMN binding
AW59_RS23160	COG4948	Mandelate Racemase Muconate Lactonizing
AW59_RS23505	COG1666	GTP binding
AW59_RS23560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW59_RS23660	COG0582	viral genome integration into host DNA
AW59_RS23775	COG0538	isocitrate dehydrogenase activity
AW59_RS23980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW59_RS24105	COG0582	viral genome integration into host DNA
AW59_RS24330	COG2134	cdp-diacylglycerol pyrophosphatase
AW59_RS24370	COG3201	nicotinamide mononucleotide transporter