locus-tag	class	description
E3399_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
E3399_RS00035	COG2271	Major facilitator Superfamily
E3399_RS00040	COG0561	phosphatase activity
E3399_RS00045	COG2186	Transcriptional regulator
E3399_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
E3399_RS00055	COG0800	Aldolase
E3399_RS00065	COG2271	Major facilitator Superfamily
E3399_RS00070	COG2198	Histidine kinase
E3399_RS00070	COG2205	protein histidine kinase activity
E3399_RS00070	COG0784	Response regulator, receiver
E3399_RS00075	COG1879	ABC-type sugar transport system periplasmic component
E3399_RS00080	COG0745	RESPONSE REGULATOR receiver
E3399_RS00085	COG3005	denitrification pathway
E3399_RS00100	COG1858	cytochrome C peroxidase
E3399_RS00110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3399_RS00115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3399_RS00120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3399_RS00130	COG1138	Cytochrome C-type biogenesis protein
E3399_RS00140	COG3088	subunit of a heme lyase
E3399_RS00140	COG4235	cytochrome complex assembly
E3399_RS00145	COG0823	Involved in the tonB-independent uptake of proteins
E3399_RS00150	COG5645	(Lipo)protein
E3399_RS00175	COG2149	membrane
E3399_RS00185	COG0641	radical SAM
E3399_RS00195	COG2610	gluconate transmembrane transporter activity
E3399_RS00200	COG0583	DNA-binding transcription factor activity
E3399_RS00210	COG2814	Major facilitator Superfamily
E3399_RS00235	COG0028	Belongs to the TPP enzyme family
E3399_RS00240	COG0440	acetolactate synthase activity
E3399_RS00245	COG1349	DNA-binding transcription factor activity
E3399_RS00255	COG0738	Major facilitator superfamily
E3399_RS00290	COG2188	Transcriptional regulator
E3399_RS00295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS00295	COG3711	transcriptional antiterminator
E3399_RS00300	COG3414	Phosphotransferase system galactitol-specific IIB component
E3399_RS00305	COG3775	system Galactitol-specific IIC component
E3399_RS00340	COG2723	6-phospho-beta-galactosidase activity
E3399_RS00360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS00360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3399_RS00365	COG3715	PTS system
E3399_RS00370	COG3716	PTS system mannose fructose sorbose family IID component
E3399_RS00385	COG5464	transposase or invertase
E3399_RS00415	COG1335	isochorismatase
E3399_RS00425	COG3710	Transcriptional regulator
E3399_RS00440	COG2771	luxR family
E3399_RS00460	COG2211	Major facilitator Superfamily
E3399_RS00465	COG1501	Belongs to the glycosyl hydrolase 31 family
E3399_RS00470	COG2982	Protein involved in outer membrane biogenesis
E3399_RS00475	COG2233	PERMEase
E3399_RS00480	COG0786	glutamate:sodium symporter activity
E3399_RS00485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E3399_RS00490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3399_RS00495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3399_RS00515	COG2860	membrane
E3399_RS00525	COG0583	DNA-binding transcription factor activity
E3399_RS00530	COG1561	YicC-like family, N-terminal region
E3399_RS00555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3399_RS00585	COG1519	Transferase
E3399_RS00590	COG0859	PFAM glycosyl transferase family 9
E3399_RS00595	COG0438	transferase activity, transferring glycosyl groups
E3399_RS00680	COG1216	Glycosyl transferase, family 2
E3399_RS00685	COG2861	carbohydrate metabolic process
E3399_RS00690	COG4942	peptidase
E3399_RS00700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3399_RS00705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3399_RS00725	COG2271	Major facilitator Superfamily
E3399_RS00735	COG1609	Transcriptional regulator
E3399_RS00740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E3399_RS00750	COG2186	Transcriptional regulator
E3399_RS00780	COG3722	fumarate hydratase activity
E3399_RS00790	COG2213	PTS system mannitol-specific
E3399_RS00790	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS00805	COG1566	PFAM secretion protein HlyD family protein
E3399_RS00810	COG0625	glutathione transferase activity
E3399_RS00820	COG3276	selenocysteine insertion sequence binding
E3399_RS00825	COG1940	carbohydrate kinase activity
E3399_RS00830	COG1012	belongs to the aldehyde dehydrogenase family
E3399_RS00845	COG0235	Class ii aldolase
E3399_RS00850	COG3623	hexulose-6-phosphate isomerase
E3399_RS00855	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E3399_RS00860	COG1070	Carbohydrate kinase
E3399_RS00865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E3399_RS00870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E3399_RS00875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E3399_RS00885	COG2731	YhcH YjgK YiaL family protein
E3399_RS00895	COG1414	Transcriptional regulator
E3399_RS00900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3399_RS00905	COG3977	Valine--pyruvate aminotransferase
E3399_RS00910	COG0366	Alpha amylase catalytic
E3399_RS00915	COG2992	FlgJ-related protein
E3399_RS00920	COG1609	Transcriptional regulator
E3399_RS00920	COG2207	Transcriptional regulator
E3399_RS00930	COG1070	Carbohydrate kinase
E3399_RS00935	COG4682	membrane
E3399_RS00940	COG3274	enterobacterial common antigen metabolic process
E3399_RS00965	COG2801	Transposase and inactivated derivatives
E3399_RS00990	COG1278	Cold shock
E3399_RS00995	COG2944	sequence-specific DNA binding
E3399_RS01005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E3399_RS01010	COG2885	chlorophyll binding
E3399_RS01015	COG0243	molybdopterin cofactor binding
E3399_RS01020	COG0456	acetyltransferase
E3399_RS01025	COG2818	Glycosylase
E3399_RS01030	COG5571	outer membrane autotransporter
E3399_RS01075	COG1609	Transcriptional regulator
E3399_RS01090	COG0747	negative chemotaxis
E3399_RS01095	COG0601	transmembrane transport
E3399_RS01100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3399_RS01105	COG0444	Belongs to the ABC transporter superfamily
E3399_RS01110	COG4608	Belongs to the ABC transporter superfamily
E3399_RS01115	COG0814	amino acid
E3399_RS01175	COG2200	EAL domain
E3399_RS01175	COG2199	diguanylate cyclase activity
E3399_RS01190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS01195	COG2200	EAL domain
E3399_RS01200	COG2982	Protein involved in outer membrane biogenesis
E3399_RS01205	COG0477	Major facilitator Superfamily
E3399_RS01210	COG1295	ribonuclease BN
E3399_RS01215	COG0583	DNA-binding transcription factor activity
E3399_RS01220	COG2197	response regulator
E3399_RS01240	COG2188	Transcriptional regulator
E3399_RS01245	COG2222	sugar isomerase
E3399_RS01250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS01255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3399_RS01265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3399_RS01270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E3399_RS01275	COG0671	phosphoesterase, PA-phosphatase related
E3399_RS01305	COG0306	phosphate transporter
E3399_RS01310	COG2081	HI0933 family
E3399_RS01315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3399_RS01320	COG0842	Transport permease protein
E3399_RS01320	COG1129	ABC transporter
E3399_RS01325	COG0842	Transport permease protein
E3399_RS01335	COG2091	lysine biosynthetic process via aminoadipic acid
E3399_RS01340	COG0628	permease
E3399_RS01355	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3399_RS01375	COG3714	YhhN family
E3399_RS01385	COG3776	membrane
E3399_RS01390	COG0742	ribosomal rna small subunit methyltransferase
E3399_RS01395	COG0552	protein localization to endoplasmic reticulum
E3399_RS01400	COG2884	Cell division ATP-binding protein ftsE
E3399_RS01405	COG2177	Part of the ABC transporter FtsEX involved in
E3399_RS01480	COG0584	glycerophosphoryl diester phosphodiesterase
E3399_RS01490	COG0405	Gamma-glutamyltransferase
E3399_RS01495	COG1735	metal-dependent hydrolase with the TIM-barrel fold
E3399_RS01510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS01515	COG1247	-acetyltransferase
E3399_RS01520	COG0673	inositol 2-dehydrogenase activity
E3399_RS01525	COG1741	Belongs to the pirin family
E3399_RS01530	COG1609	Transcriptional regulator
E3399_RS01535	COG3265	gluconokinase activity
E3399_RS01540	COG2610	gluconate transmembrane transporter activity
E3399_RS01575	COG0058	SHG alpha-glucan phosphorylase activity
E3399_RS01580	COG1414	Transcriptional regulator
E3399_RS01585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E3399_RS01590	COG0129	dihydroxy-acid dehydratase activity
E3399_RS01600	COG0371	Dehydrogenase
E3399_RS01615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E3399_RS01630	COG1349	DNA-binding transcription factor activity
E3399_RS01635	COG4650	regulator
E3399_RS01645	COG1690	Belongs to the RtcB family
E3399_RS01655	COG3077	Addiction module antitoxin, RelB DinJ family
E3399_RS01660	COG3041	Addiction module toxin RelE StbE family
E3399_RS01670	COG0058	SHG alpha-glucan phosphorylase activity
E3399_RS01675	COG1640	4-alpha-glucanotransferase
E3399_RS01680	COG2610	gluconate transmembrane transporter activity
E3399_RS01690	COG1040	competence protein
E3399_RS01700	COG5464	transposase or invertase
E3399_RS01715	COG1918	ferrous iron import across plasma membrane
E3399_RS01720	COG2183	response to ionizing radiation
E3399_RS01725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3399_RS01745	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E3399_RS01755	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3399_RS01760	COG1011	Hydrolase
E3399_RS01770	COG0494	nUDIX hydrolase
E3399_RS01775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E3399_RS01780	COG4972	Pilus assembly protein
E3399_RS01785	COG3166	PFAM Fimbrial assembly family protein
E3399_RS01800	COG4796	Type ii and iii secretion system protein
E3399_RS01815	COG3266	domain, Protein
E3399_RS01820	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E3399_RS01825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3399_RS01865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3399_RS01900	COG1289	transmembrane transporter activity
E3399_RS01910	COG1765	OsmC-like protein
E3399_RS01915	COG3954	Phosphoribulokinase
E3399_RS01925	COG0429	hydrolase of the alpha beta-hydrolase fold
E3399_RS01940	COG0488	(ABC) transporter
E3399_RS01955	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E3399_RS01960	COG1047	Peptidyl-prolyl cis-trans
E3399_RS01970	COG0545	Peptidyl-prolyl cis-trans isomerase
E3399_RS01975	COG2964	Protein conserved in bacteria
E3399_RS02030	COG0051	transcription antitermination factor activity, RNA binding
E3399_RS02055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E3399_RS02135	COG0201	protein transport
E3399_RS02175	COG0789	Transcriptional regulator
E3399_RS02180	COG3036	rescue of stalled ribosome
E3399_RS02210	COG0758	DNA mediated transformation
E3399_RS02220	COG0551	DNA topoisomerase type I activity
E3399_RS02240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E3399_RS02280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3399_RS02285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3399_RS02290	COG1309	transcriptional regulator
E3399_RS02305	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E3399_RS02330	COG4145	pantothenate transmembrane transporter activity
E3399_RS02335	COG3924	membrane
E3399_RS02340	COG0439	Biotin carboxylase
E3399_RS02345	COG0511	ligase activity, forming carbon-carbon bonds
E3399_RS02360	COG0604	alcohol dehydrogenase
E3399_RS02365	COG2199	diguanylate cyclase activity
E3399_RS02365	COG2200	EAL domain
E3399_RS02370	COG1077	Cell shape determining protein MreB Mrl
E3399_RS02375	COG1792	Involved in formation and maintenance of cell shape
E3399_RS02380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E3399_RS02395	COG3164	Protein of unknown function
E3399_RS02400	COG0312	modulator of DNA gyrase
E3399_RS02405	COG0583	DNA-binding transcription factor activity
E3399_RS02425	COG2732	(Barnase) inhibitor
E3399_RS02450	COG2188	Transcriptional regulator
E3399_RS02460	COG0471	metal ion transport
E3399_RS02465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3399_RS02470	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3399_RS02475	COG3630	sodium ion export across plasma membrane
E3399_RS02480	COG5016	pyruvate
E3399_RS02480	COG0511	ligase activity, forming carbon-carbon bonds
E3399_RS02500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3399_RS02505	COG3105	Protein conserved in bacteria
E3399_RS02510	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E3399_RS02535	COG0625	glutathione transferase activity
E3399_RS02540	COG2969	positive regulation of protein catabolic process
E3399_RS02570	COG2731	YhcH YjgK YiaL family protein
E3399_RS02575	COG0402	S-adenosylhomocysteine deaminase activity
E3399_RS02580	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E3399_RS02585	COG4804	nuclease activity
E3399_RS02590	COG0493	'glutamate synthase
E3399_RS02595	COG0067	glutamate synthase
E3399_RS02595	COG0069	glutamate synthase activity
E3399_RS02595	COG0070	glutamate synthase
E3399_RS02600	COG1242	4 iron, 4 sulfur cluster binding
E3399_RS02605	COG0784	Response regulator, receiver
E3399_RS02605	COG2198	Histidine kinase
E3399_RS02605	COG5002	protein histidine kinase activity
E3399_RS02610	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E3399_RS02620	COG0515	serine threonine protein kinase
E3399_RS02625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS02650	COG1137	ATPase activity
E3399_RS02655	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E3399_RS02660	COG3117	lipopolysaccharide transmembrane transporter activity
E3399_RS02665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E3399_RS02675	COG0530	calcium, potassium:sodium antiporter activity
E3399_RS02680	COG1127	ABC transporter
E3399_RS02685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3399_RS02690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3399_RS02695	COG2854	intermembrane phospholipid transfer
E3399_RS02700	COG3113	response to antibiotic
E3399_RS02705	COG5007	Belongs to the BolA IbaG family
E3399_RS02715	COG3423	Transcriptional regulator
E3399_RS02720	COG0142	geranyltranstransferase activity
E3399_RS02735	COG0697	spore germination
E3399_RS02745	COG2027	D-alanyl-D-alanine carboxypeptidase
E3399_RS02755	COG1534	Rna-binding protein
E3399_RS02770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E3399_RS02780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3399_RS02850	COG0513	Belongs to the DEAD box helicase family
E3399_RS02855	COG0814	amino acid
E3399_RS02865	COG3034	peptidoglycan biosynthetic process
E3399_RS02870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3399_RS02875	COG0826	peptidase U32
E3399_RS02880	COG0826	peptidase U32
E3399_RS02885	COG3154	lipid carrier protein
E3399_RS02890	COG3153	acetyltransferase
E3399_RS02905	COG0693	protein deglycase activity
E3399_RS02910	COG0702	epimerase
E3399_RS02915	COG2823	Periplasmic or secreted lipoprotein
E3399_RS02935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3399_RS02945	COG1063	alcohol dehydrogenase
E3399_RS02950	COG3775	system Galactitol-specific IIC component
E3399_RS02955	COG3414	Phosphotransferase system galactitol-specific IIB component
E3399_RS02960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS02975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3399_RS02975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3399_RS02975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS02980	COG1105	Belongs to the carbohydrate kinase PfkB family
E3399_RS02990	COG1349	DNA-binding transcription factor activity
E3399_RS02995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS03000	COG2721	sulfolactate sulfo-lyase activity
E3399_RS03010	COG2084	Dehydrogenase
E3399_RS03015	COG1929	Belongs to the glycerate kinase type-1 family
E3399_RS03025	COG0583	DNA-binding transcription factor activity
E3399_RS03045	COG1882	Formate acetyltransferase
E3399_RS03050	COG1760	l-serine dehydratase
E3399_RS03055	COG0814	amino acid
E3399_RS03070	COG1741	Belongs to the pirin family
E3399_RS03075	COG0583	DNA-binding transcription factor activity
E3399_RS03080	COG3152	Membrane
E3399_RS03085	COG0435	Glutathione S-transferase
E3399_RS03090	COG2259	Doxx family
E3399_RS03100	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E3399_RS03105	COG4575	ribosome binding
E3399_RS03110	COG1422	Protein of unknown function (DUF1090)
E3399_RS03120	COG0586	Pfam SNARE associated Golgi protein
E3399_RS03135	COG0673	inositol 2-dehydrogenase activity
E3399_RS03140	COG2949	membrane
E3399_RS03145	COG1451	nucleotide metabolic process
E3399_RS03155	COG1902	pentaerythritol trinitrate reductase activity
E3399_RS03155	COG0446	pyridine nucleotide-disulphide oxidoreductase
E3399_RS03165	COG0840	transmembrane signaling receptor activity
E3399_RS03165	COG0840	transmembrane signaling receptor activity
E3399_RS03170	COG0840	transmembrane signaling receptor activity
E3399_RS03175	COG1695	Transcriptional regulator
E3399_RS03180	COG2375	cellular response to nickel ion
E3399_RS03205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E3399_RS03230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E3399_RS03245	COG4991	sh3 domain protein
E3399_RS03250	COG3025	triphosphatase activity
E3399_RS03270	COG2268	Band 7 protein
E3399_RS03275	COG1585	Membrane protein implicated in regulation of membrane protease activity
E3399_RS03315	COG3384	dioxygenase
E3399_RS03320	COG0754	glutathionylspermidine amidase activity
E3399_RS03335	COG0494	nUDIX hydrolase
E3399_RS03340	COG3151	Protein conserved in bacteria
E3399_RS03345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E3399_RS03350	COG3150	esterase
E3399_RS03360	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E3399_RS03365	COG2249	NAD(P)H dehydrogenase (quinone) activity
E3399_RS03380	COG3111	PFAM Bacterial OB fold (BOF) protein
E3399_RS03385	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E3399_RS03435	COG0471	metal ion transport
E3399_RS03445	COG1979	alcohol dehydrogenase
E3399_RS03450	COG2207	Transcriptional regulator
E3399_RS03470	COG0848	biopolymer transport protein
E3399_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
E3399_RS03500	COG0840	transmembrane signaling receptor activity
E3399_RS03510	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3399_RS03515	COG0437	4 iron, 4 sulfur cluster binding
E3399_RS03520	COG5557	Pfam Polysulphide reductase, NrfD
E3399_RS03525	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E3399_RS03530	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3399_RS03535	COG1773	rubredoxin
E3399_RS03545	COG0298	carbon dioxide binding
E3399_RS03550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3399_RS03560	COG0625	glutathione transferase activity
E3399_RS03565	COG0754	glutathionylspermidine amidase activity
E3399_RS03580	COG0246	Mannitol dehydrogenase
E3399_RS03590	COG2271	Major facilitator Superfamily
E3399_RS03615	COG1012	belongs to the aldehyde dehydrogenase family
E3399_RS03620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E3399_RS03630	COG0531	amino acid
E3399_RS03660	COG2301	Belongs to the HpcH HpaI aldolase family
E3399_RS03665	COG2030	dehydratase
E3399_RS03670	COG0427	acetyl-CoA hydrolase
E3399_RS03685	COG1811	Na channel or pump
E3399_RS03690	COG1982	Orn Lys Arg decarboxylase major
E3399_RS03695	COG2211	Major facilitator Superfamily
E3399_RS03720	COG3171	Protein conserved in bacteria
E3399_RS03730	COG0252	asparaginase activity
E3399_RS03740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3399_RS03755	COG0762	integral membrane protein
E3399_RS03760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3399_RS03765	COG2805	Type II/IV secretion system protein
E3399_RS03790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3399_RS03795	COG2356	endonuclease I
E3399_RS03805	COG2814	Major facilitator Superfamily
E3399_RS03820	COG1166	arginine decarboxylase activity
E3399_RS03830	COG2186	Transcriptional regulator
E3399_RS03840	COG0246	Mannitol dehydrogenase
E3399_RS03845	COG1063	alcohol dehydrogenase
E3399_RS03850	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E3399_RS03855	COG2731	YhcH YjgK YiaL family protein
E3399_RS03860	COG2267	carboxylic ester hydrolase activity
E3399_RS03870	COG0501	Belongs to the peptidase M48B family
E3399_RS03875	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E3399_RS03880	COG1122	ATPase activity
E3399_RS03885	COG1122	ATPase activity
E3399_RS03915	COG0191	fructose-bisphosphate aldolase activity
E3399_RS03920	COG0668	transmembrane transport
E3399_RS03930	COG2968	Membrane
E3399_RS03945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3399_RS03950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3399_RS03970	COG0006	proline dipeptidase activity
E3399_RS03975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3399_RS03980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3399_RS04010	COG2723	6-phospho-beta-galactosidase activity
E3399_RS04020	COG1272	protein, Hemolysin III
E3399_RS04080	COG4942	peptidase
E3399_RS04090	COG0582	viral genome integration into host DNA
E3399_RS04120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E3399_RS04155	COG0431	NADPH-dependent FMN reductase
E3399_RS04190	COG3121	Chaperone
E3399_RS04195	COG3188	usher protein
E3399_RS04205	COG1285	pathogenesis
E3399_RS04250	COG0406	alpha-ribazole phosphatase activity
E3399_RS04255	COG2015	COG2015, Alkyl sulfatase and related hydrolases
E3399_RS04260	COG3264	Mechanosensitive ion channel
E3399_RS04260	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
E3399_RS04265	COG2067	long-chain fatty acid transport protein
E3399_RS04270	COG3596	GTP binding
E3399_RS04275	COG2378	regulation of single-species biofilm formation
E3399_RS04285	COG2378	regulation of single-species biofilm formation
E3399_RS04310	COG2003	Belongs to the UPF0758 family
E3399_RS04360	COG3188	usher protein
E3399_RS04395	COG0814	amino acid
E3399_RS04410	COG0183	Belongs to the thiolase family
E3399_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
E3399_RS04425	COG2814	Major facilitator Superfamily
E3399_RS04430	COG1794	racemase activity, acting on amino acids and derivatives
E3399_RS04435	COG0583	DNA-binding transcription factor activity
E3399_RS04445	COG1609	Transcriptional regulator
E3399_RS04465	COG0667	Aldo Keto reductase
E3399_RS04475	COG0861	Integral membrane protein TerC family
E3399_RS04510	COG2165	general secretion pathway protein
E3399_RS04515	COG4795	General secretion pathway protein
E3399_RS04525	COG4967	type IV pilus modification protein PilV
E3399_RS04530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E3399_RS04540	COG1074	ATP-dependent DNA helicase activity
E3399_RS04545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3399_RS04555	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3399_RS04570	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E3399_RS04575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3399_RS04580	COG2962	Rard protein
E3399_RS04585	COG2166	iron-sulfur cluster assembly
E3399_RS04590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3399_RS04600	COG0583	DNA-binding transcription factor activity
E3399_RS04605	COG2363	Small membrane protein
E3399_RS04615	COG1349	DNA-binding transcription factor activity
E3399_RS04635	COG0738	Major facilitator superfamily
E3399_RS04640	COG0235	Class ii aldolase
E3399_RS04645	COG1454	alcohol dehydrogenase
E3399_RS04655	COG1760	l-serine dehydratase
E3399_RS04660	COG0814	amino acid
E3399_RS04665	COG1611	Belongs to the LOG family
E3399_RS04685	COG3098	single-species biofilm formation
E3399_RS04695	COG0716	FMN binding
E3399_RS04705	COG2271	Major facilitator Superfamily
E3399_RS04710	COG4948	Mandelate Racemase Muconate Lactonizing
E3399_RS04715	COG4948	Mandelate Racemase Muconate Lactonizing
E3399_RS04720	COG1929	Belongs to the glycerate kinase type-1 family
E3399_RS04725	COG2205	protein histidine kinase activity
E3399_RS04725	COG3437	response regulator, receiver
E3399_RS04725	COG4999	Histidine kinase
E3399_RS04725	COG3850	Histidine kinase
E3399_RS04735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3399_RS04740	COG3609	addiction module antidote protein, CC2985 family
E3399_RS04770	COG3539	Fimbrial protein
E3399_RS04775	COG3121	Chaperone
E3399_RS04780	COG3188	usher protein
E3399_RS04785	COG3539	Fimbrial protein
E3399_RS04790	COG3956	TIGRFAM MazG family protein
E3399_RS04805	COG0602	queuosine metabolic process
E3399_RS04810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3399_RS04810	COG0321	lipoyl(octanoyl) transferase activity
E3399_RS04815	COG0720	synthase
E3399_RS04840	COG1203	CRISPR-associated helicase, Cas3
E3399_RS04855	COG1857	crispr-associated protein
E3399_RS04870	COG1518	maintenance of DNA repeat elements
E3399_RS04875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3399_RS04880	COG2234	aminopeptidase activity
E3399_RS04935	COG1388	LysM domain
E3399_RS04935	COG4942	peptidase
E3399_RS04950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E3399_RS04955	COG0163	prenyltransferase activity
E3399_RS04965	COG1349	DNA-binding transcription factor activity
E3399_RS04970	COG2084	Dehydrogenase
E3399_RS04980	COG0235	Class ii aldolase
E3399_RS04985	COG3622	Belongs to the hyi family
E3399_RS04990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3399_RS04995	COG2610	gluconate transmembrane transporter activity
E3399_RS05005	COG0477	Major facilitator Superfamily
E3399_RS05085	COG2207	Transcriptional regulator
E3399_RS05175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E3399_RS05195	COG0741	lytic transglycosylase activity
E3399_RS05260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3399_RS05265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3399_RS05270	COG1121	(ABC) transporter
E3399_RS05290	COG0309	Hydrogenase expression formation protein (HypE)
E3399_RS05295	COG0409	Hydrogenase expression formation protein
E3399_RS05300	COG0298	carbon dioxide binding
E3399_RS05305	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E3399_RS05320	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3399_RS05325	COG0651	ATP synthesis coupled electron transport
E3399_RS05330	COG0650	Formate hydrogenlyase subunit 4
E3399_RS05335	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E3399_RS05335	COG3261	NADH dehydrogenase
E3399_RS05340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3399_RS05345	COG3260	NADH ubiquinone oxidoreductase 20
E3399_RS05355	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3399_RS05365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3399_RS05370	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E3399_RS05395	COG1349	DNA-binding transcription factor activity
E3399_RS05400	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
E3399_RS05415	COG3732	PTS system glucitol sorbitol-specific
E3399_RS05420	COG3730	PTS system glucitol sorbitol-specific
E3399_RS05425	COG2951	lytic endotransglycosylase activity
E3399_RS05435	COG1546	Belongs to the CinA family
E3399_RS05460	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E3399_RS05490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3399_RS05495	COG1238	metal cluster binding
E3399_RS05515	COG2814	Major facilitator Superfamily
E3399_RS05520	COG1566	PFAM secretion protein HlyD family protein
E3399_RS05525	COG1846	Transcriptional regulator
E3399_RS05530	COG2814	Major facilitator Superfamily
E3399_RS05575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3399_RS05585	COG4575	ribosome binding
E3399_RS05615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3399_RS05620	COG0640	Transcriptional regulator
E3399_RS05625	COG0401	homolog of Blt101
E3399_RS05635	COG1652	LysM domain
E3399_RS05640	COG1802	Transcriptional regulator
E3399_RS05645	COG1113	amino acid transport
E3399_RS05650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3399_RS05655	COG1012	belongs to the aldehyde dehydrogenase family
E3399_RS05660	COG0579	oxidoreductase
E3399_RS05695	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3399_RS05710	COG2990	Protein conserved in bacteria
E3399_RS05730	COG2819	hydrolase of the alpha beta superfamily
E3399_RS05740	COG1132	(ABC) transporter
E3399_RS05805	COG0582	viral genome integration into host DNA
E3399_RS05815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3399_RS05840	COG2867	negative regulation of translational initiation
E3399_RS05855	COG0497	DNA recombination
E3399_RS05875	COG4536	flavin adenine dinucleotide binding
E3399_RS05880	COG4137	Cytochrome C assembly protein
E3399_RS05885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3399_RS05910	COG2199	diguanylate cyclase activity
E3399_RS05925	COG1605	Chorismate mutase
E3399_RS05925	COG0287	Prephenate dehydrogenase
E3399_RS05935	COG1605	Chorismate mutase
E3399_RS05935	COG0077	Prephenate dehydratase
E3399_RS05945	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E3399_RS05955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3399_RS05970	COG0542	response to heat
E3399_RS06000	COG0477	Major facilitator Superfamily
E3399_RS06005	COG5544	Lipoprotein
E3399_RS06010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3399_RS06020	COG3148	PFAM DTW domain containing protein
E3399_RS06025	COG3118	belongs to the thioredoxin family
E3399_RS06030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3399_RS06050	COG0583	DNA-binding transcription factor activity
E3399_RS06055	COG0513	Belongs to the DEAD box helicase family
E3399_RS06065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E3399_RS06095	COG3086	response to oxidative stress
E3399_RS06135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3399_RS06140	COG0583	DNA-binding transcription factor activity
E3399_RS06145	COG2223	nitrite transmembrane transporter activity
E3399_RS06150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3399_RS06155	COG1737	Transcriptional regulator
E3399_RS06165	COG1263	PTS System
E3399_RS06165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3399_RS06170	COG0560	Phosphoserine phosphatase
E3399_RS06195	COG2205	protein histidine kinase activity
E3399_RS06200	COG3170	Tfp pilus assembly protein FimV
E3399_RS06205	COG2204	response regulator
E3399_RS06210	COG0347	Belongs to the P(II) protein family
E3399_RS06215	COG3104	oligopeptide transport
E3399_RS06225	COG0531	amino acid
E3399_RS06230	COG3710	Transcriptional regulator
E3399_RS06245	COG2814	Major facilitator Superfamily
E3399_RS06250	COG3711	transcriptional antiterminator
E3399_RS06260	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E3399_RS06305	COG0822	iron-sulfur transferase activity
E3399_RS06325	COG0633	Ferredoxin
E3399_RS06330	COG2975	iron-sulfur cluster assembly
E3399_RS06355	COG2897	thiosulfate sulfurtransferase activity
E3399_RS06360	COG2373	Large extracellular alpha-helical protein
E3399_RS06365	COG4953	penicillin-binding protein 1C
E3399_RS06370	COG0243	molybdopterin cofactor binding
E3399_RS06375	COG0437	4 iron, 4 sulfur cluster binding
E3399_RS06415	COG2976	Protein conserved in bacteria
E3399_RS06430	COG1645	bacterial-type flagellum-dependent swarming motility
E3399_RS06470	COG0517	IMP dehydrogenase activity
E3399_RS06470	COG0516	GMP reductase activity
E3399_RS06505	COG2200	EAL domain
E3399_RS06520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E3399_RS06535	COG2233	PERMEase
E3399_RS06545	COG1393	Belongs to the ArsC family
E3399_RS06555	COG0628	permease
E3399_RS06560	COG3835	regulator
E3399_RS06565	COG2610	gluconate transmembrane transporter activity
E3399_RS06570	COG1929	Belongs to the glycerate kinase type-1 family
E3399_RS06575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3399_RS06580	COG2716	regulation of RNA biosynthetic process
E3399_RS06585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E3399_RS06590	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E3399_RS06600	COG2321	neutral zinc metallopeptidase
E3399_RS06620	COG1393	Belongs to the ArsC family
E3399_RS06630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3399_RS06635	COG3850	Histidine kinase
E3399_RS06640	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3399_RS06640	COG0493	'glutamate synthase
E3399_RS06655	COG5342	invasion associated locus B
E3399_RS06665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E3399_RS06800	COG2837	iron assimilation
E3399_RS06820	COG4208	sulfate ABC transporter
E3399_RS06875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS06900	COG3530	Putative quorum-sensing-regulated virulence factor
E3399_RS06905	COG0385	Bile acid
E3399_RS06910	COG0583	DNA-binding transcription factor activity
E3399_RS06920	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E3399_RS06925	COG2211	Major facilitator Superfamily
E3399_RS06935	COG0583	DNA-binding transcription factor activity
E3399_RS06960	COG3415	Transposase
E3399_RS06965	COG3415	Transposase
E3399_RS06980	COG2199	diguanylate cyclase activity
E3399_RS06980	COG2200	EAL domain
E3399_RS06985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3399_RS07000	COG0667	Aldo Keto reductase
E3399_RS07005	COG3961	Belongs to the TPP enzyme family
E3399_RS07020	COG0436	Aminotransferase
E3399_RS07030	COG1560	Kdo2-lipid A biosynthetic process
E3399_RS07070	COG2116	formate transmembrane transporter activity
E3399_RS07085	COG3691	Protein conserved in bacteria
E3399_RS07100	COG2062	phosphohistidine phosphatase, SixA
E3399_RS07125	COG0730	response to heat
E3399_RS07130	COG3101	peptidyl-lysine hydroxylation
E3399_RS07145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3399_RS07165	COG3423	Transcriptional regulator
E3399_RS07190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3399_RS07200	COG0586	Pfam SNARE associated Golgi protein
E3399_RS07210	COG0285	dihydrofolate synthase activity
E3399_RS07215	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E3399_RS07220	COG1286	toxin biosynthetic process
E3399_RS07225	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E3399_RS07230	COG3829	transcription factor binding
E3399_RS07240	COG0531	amino acid
E3399_RS07245	COG3457	Alanine racemase
E3399_RS07250	COG0833	amino acid
E3399_RS07285	COG1090	epimerase
E3399_RS07290	COG0625	glutathione transferase activity
E3399_RS07295	COG0625	glutathione transferase activity
E3399_RS07300	COG0622	Phosphoesterase
E3399_RS07310	COG1609	Transcriptional regulator
E3399_RS07315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS07325	COG3037	sugar-specific permease SgaT UlaA
E3399_RS07330	COG3959	Transketolase, thiamine diphosphate binding domain
E3399_RS07335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E3399_RS07340	COG1288	antiporter activity
E3399_RS07365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3399_RS07370	COG0471	metal ion transport
E3399_RS07370	COG0490	domain, Protein
E3399_RS07385	COG0436	Aminotransferase
E3399_RS07390	COG0583	DNA-binding transcription factor activity
E3399_RS07440	COG0839	Belongs to the complex I subunit 6 family
E3399_RS07450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3399_RS07455	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3399_RS07465	COG0784	Response regulator, receiver
E3399_RS07465	COG0835	chemotaxis
E3399_RS07475	COG2153	protein acetylation
E3399_RS07480	COG4575	ribosome binding
E3399_RS07485	COG1169	isochorismate synthase
E3399_RS07575	COG1414	Transcriptional regulator
E3399_RS07585	COG2271	Major facilitator Superfamily
E3399_RS07605	COG0247	lactate metabolic process
E3399_RS07615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E3399_RS07620	COG2271	Major facilitator Superfamily
E3399_RS07625	COG0584	glycerophosphoryl diester phosphodiesterase
E3399_RS07630	COG0583	DNA-binding transcription factor activity
E3399_RS07635	COG2814	Major facilitator Superfamily
E3399_RS07640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3399_RS07670	COG4948	Mandelate Racemase Muconate Lactonizing
E3399_RS07690	COG2198	Histidine kinase
E3399_RS07690	COG0642	Histidine kinase
E3399_RS07715	COG4615	Cyclic peptide transporter
E3399_RS07725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3399_RS07725	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3399_RS07730	COG3062	negative regulation of establishment of protein localization
E3399_RS07740	COG0437	4 iron, 4 sulfur cluster binding
E3399_RS07745	COG0348	domain, Protein
E3399_RS07750	COG3043	anaerobic respiration
E3399_RS07755	COG3005	denitrification pathway
E3399_RS07765	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3399_RS07770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3399_RS07775	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3399_RS07785	COG1138	Cytochrome C-type biogenesis protein
E3399_RS07795	COG3088	subunit of a heme lyase
E3399_RS07795	COG4235	cytochrome complex assembly
E3399_RS07800	COG2197	response regulator
E3399_RS07815	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3399_RS07865	COG1061	Type III restriction enzyme res subunit
E3399_RS07875	COG2814	Major facilitator Superfamily
E3399_RS07885	COG4172	Belongs to the ABC transporter superfamily
E3399_RS07890	COG4239	(ABC) transporter, permease
E3399_RS07895	COG4174	ABC transporter (Permease)
E3399_RS07900	COG4166	transmembrane transport
E3399_RS07905	COG2200	EAL domain
E3399_RS07910	COG0791	NLP P60 protein
E3399_RS07915	COG0671	phosphoesterase, PA-phosphatase related
E3399_RS07920	COG0523	cobalamin synthesis protein
E3399_RS07955	COG1105	Belongs to the carbohydrate kinase PfkB family
E3399_RS07960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3399_RS07960	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E3399_RS07960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3399_RS07970	COG2855	membrane
E3399_RS07975	COG0583	DNA-binding transcription factor activity
E3399_RS07980	COG0833	amino acid
E3399_RS07985	COG4771	TonB-dependent receptor
E3399_RS07990	COG2271	Major facilitator Superfamily
E3399_RS07995	COG0560	Phosphoserine phosphatase
E3399_RS08000	COG1760	l-serine dehydratase
E3399_RS08020	COG2311	Membrane
E3399_RS08050	COG0493	'glutamate synthase
E3399_RS08060	COG2949	membrane
E3399_RS08070	COG1346	cytolysis
E3399_RS08085	COG2271	Major facilitator Superfamily
E3399_RS08100	COG0625	glutathione transferase activity
E3399_RS08105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3399_RS08120	COG1538	Outer membrane efflux protein
E3399_RS08125	COG1028	Short-chain dehydrogenase reductase Sdr
E3399_RS08130	COG0586	Pfam SNARE associated Golgi protein
E3399_RS08140	COG1686	Belongs to the peptidase S11 family
E3399_RS08145	COG0277	FAD linked oxidase domain protein
E3399_RS08155	COG1732	Glycine betaine
E3399_RS08160	COG1174	glycine betaine transport
E3399_RS08165	COG1125	glycine betaine transport
E3399_RS08170	COG1174	glycine betaine transport
E3399_RS08185	COG3275	phosphorelay sensor kinase activity
E3399_RS08195	COG4807	Protein conserved in bacteria
E3399_RS08205	COG4808	Protein conserved in bacteria
E3399_RS08230	COG3121	Chaperone
E3399_RS08235	COG3188	usher protein
E3399_RS08240	COG3539	Fimbrial protein
E3399_RS08245	COG5455	response to cobalt ion
E3399_RS08260	COG2188	Transcriptional regulator
E3399_RS08265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS08270	COG1397	ADP-ribosylglycohydrolase
E3399_RS08275	COG2211	Major facilitator Superfamily
E3399_RS08280	COG1830	Aldolase
E3399_RS08305	COG0826	peptidase U32
E3399_RS08325	COG0745	RESPONSE REGULATOR receiver
E3399_RS08330	COG2205	protein histidine kinase activity
E3399_RS08360	COG0443	Heat shock 70 kDa protein
E3399_RS08365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E3399_RS08370	COG5001	Diguanylate cyclase
E3399_RS08370	COG5002	protein histidine kinase activity
E3399_RS08370	COG3447	MASE1 domain protein
E3399_RS08385	COG2982	Protein involved in outer membrane biogenesis
E3399_RS08390	COG1253	flavin adenine dinucleotide binding
E3399_RS08410	COG0463	Glycosyl transferase, family 2
E3399_RS08415	COG1045	serine acetyltransferase
E3399_RS08420	COG0438	transferase activity, transferring glycosyl groups
E3399_RS08430	COG1216	Glycosyl transferase, family 2
E3399_RS08435	COG0110	maltose O-acetyltransferase activity
E3399_RS08440	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E3399_RS08445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3399_RS08455	COG0297	glycogen (starch) synthase activity
E3399_RS08470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3399_RS08475	COG2244	polysaccharide biosynthetic process
E3399_RS08480	COG2327	Polysaccharide pyruvyl transferase
E3399_RS08510	COG0438	transferase activity, transferring glycosyl groups
E3399_RS08595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3399_RS08600	COG0583	DNA-binding transcription factor activity
E3399_RS08610	COG0531	amino acid
E3399_RS08615	COG2925	Exonuclease
E3399_RS08655	COG1289	transmembrane transporter activity
E3399_RS08690	COG4656	Part of a membrane complex involved in electron transport
E3399_RS08695	COG1012	belongs to the aldehyde dehydrogenase family
E3399_RS08695	COG1454	alcohol dehydrogenase
E3399_RS08710	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
E3399_RS08725	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E3399_RS08855	COG1122	ATPase activity
E3399_RS08890	COG0534	Mate efflux family protein
E3399_RS08940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E3399_RS08985	COG0582	viral genome integration into host DNA
E3399_RS09035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3399_RS09045	COG1418	mRNA catabolic process
E3399_RS09050	COG0270	DNA (cytosine-5-)-methyltransferase activity
E3399_RS09055	COG3727	T/G mismatch-specific endonuclease activity
E3399_RS09060	COG0697	spore germination
E3399_RS09065	COG2354	Protein conserved in bacteria
E3399_RS09070	COG5475	Uncharacterized small protein (DUF2158)
E3399_RS09175	COG0425	Belongs to the sulfur carrier protein TusA family
E3399_RS09230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3399_RS09240	COG0765	amino acid transport
E3399_RS09245	COG1126	abc transporter atp-binding protein
E3399_RS09250	COG2197	response regulator
E3399_RS09265	COG2197	response regulator
E3399_RS09310	COG3012	SEC-C Motif Domain Protein
E3399_RS09310	COG3318	Belongs to the UPF0149 family
E3399_RS09315	COG0814	amino acid
E3399_RS09325	COG1528	Iron-storage protein
E3399_RS09340	COG1528	Iron-storage protein
E3399_RS09445	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E3399_RS09460	COG3102	Protein conserved in bacteria
E3399_RS09480	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E3399_RS09485	COG1801	Protein of unknown function DUF72
E3399_RS09490	COG1335	isochorismatase
E3399_RS09500	COG0494	nUDIX hydrolase
E3399_RS09540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3399_RS09550	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E3399_RS09555	COG0739	heme binding
E3399_RS09560	COG1560	Kdo2-lipid A biosynthetic process
E3399_RS09570	COG1737	Transcriptional regulator
E3399_RS09575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3399_RS09580	COG0129	dihydroxy-acid dehydratase activity
E3399_RS09585	COG0800	Aldolase
E3399_RS09595	COG3141	response to X-ray
E3399_RS09605	COG2979	Protein of unknown function (DUF533)
E3399_RS09610	COG1770	oligopeptidase
E3399_RS09615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3399_RS09620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3399_RS09630	COG2372	response to copper ion
E3399_RS09635	COG1276	copper resistance
E3399_RS09655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3399_RS09755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E3399_RS09775	COG5562	phage envelope protein
E3399_RS09810	COG3008	intermembrane lipid transfer
E3399_RS09815	COG2995	paraquat-inducible protein a
E3399_RS09820	COG1956	GAF domain-containing protein
E3399_RS09840	COG2814	Major facilitator Superfamily
E3399_RS09845	COG1414	Transcriptional regulator
E3399_RS09875	COG0768	penicillin binding
E3399_RS09880	COG2226	methyltransferase
E3399_RS09895	COG3716	PTS system mannose fructose sorbose family IID component
E3399_RS09900	COG3715	PTS system
E3399_RS09905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3399_RS09905	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS09910	COG1253	flavin adenine dinucleotide binding
E3399_RS09915	COG2200	EAL domain
E3399_RS09920	COG1760	l-serine dehydratase
E3399_RS09940	COG0251	oxidation-reduction process
E3399_RS09945	COG1199	ATP-dependent helicase activity
E3399_RS09955	COG3065	identical protein binding
E3399_RS09965	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E3399_RS09975	COG2894	cell division
E3399_RS09990	COG0179	Fumarylacetoacetate (FAA) hydrolase
E3399_RS10030	COG2719	SpoVR family
E3399_RS10050	COG1619	proteins homologs of microcin C7 resistance protein MccF
E3399_RS10075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E3399_RS10085	COG1294	oxidase, subunit
E3399_RS10090	COG1271	oxidase subunit
E3399_RS10095	COG1773	rubredoxin
E3399_RS10100	COG1999	signal sequence binding
E3399_RS10105	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3399_RS10110	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E3399_RS10120	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3399_RS10135	COG0012	GTP binding
E3399_RS10150	COG0659	secondary active sulfate transmembrane transporter activity
E3399_RS10200	COG0387	Pfam Sodium calcium exchanger
E3399_RS10205	COG4572	Cation transport regulator
E3399_RS10210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E3399_RS10215	COG4932	domain protein
E3399_RS10220	COG2197	response regulator
E3399_RS10225	COG3850	Histidine kinase
E3399_RS10230	COG2223	nitrite transmembrane transporter activity
E3399_RS10235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3399_RS10240	COG1140	nitrate reductase beta subunit
E3399_RS10245	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E3399_RS10250	COG2181	nitrate reductase activity
E3399_RS10295	COG0788	formyltetrahydrofolate deformylase activity
E3399_RS10305	COG1752	Esterase of the alpha-beta hydrolase superfamily
E3399_RS10310	COG0745	RESPONSE REGULATOR receiver
E3399_RS10315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E3399_RS10330	COG1012	belongs to the aldehyde dehydrogenase family
E3399_RS10330	COG1454	alcohol dehydrogenase
E3399_RS10335	COG2095	MarC family integral membrane protein
E3399_RS10365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3399_RS10385	COG2350	Protein conserved in bacteria
E3399_RS10410	COG0727	PFAM Uncharacterised protein family (UPF0153)
E3399_RS10420	COG3546	catalase activity
E3399_RS10425	COG3685	Protein conserved in bacteria
E3399_RS10430	COG3685	Protein conserved in bacteria
E3399_RS10435	COG3729	General stress protein
E3399_RS10450	COG0135	phosphoribosylanthranilate isomerase activity
E3399_RS10450	COG0134	indole-3-glycerol-phosphate synthase activity
E3399_RS10475	COG0009	L-threonylcarbamoyladenylate synthase
E3399_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
E3399_RS10495	COG0616	signal peptide processing
E3399_RS10540	COG0671	phosphoesterase, PA-phosphatase related
E3399_RS10545	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E3399_RS10550	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E3399_RS10570	COG1349	DNA-binding transcription factor activity
E3399_RS10580	COG5001	Diguanylate cyclase
E3399_RS10590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3399_RS10590	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3399_RS10645	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E3399_RS10650	COG1842	Phage shock protein A
E3399_RS10660	COG1983	PspC domain protein
E3399_RS10670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3399_RS10675	COG3106	COG3106 Predicted ATPase
E3399_RS10695	COG4948	Mandelate Racemase Muconate Lactonizing
E3399_RS10700	COG2866	Carboxypeptidase
E3399_RS10705	COG4166	transmembrane transport
E3399_RS10715	COG0583	DNA-binding transcription factor activity
E3399_RS10720	COG0656	L-ascorbic acid biosynthetic process
E3399_RS10725	COG1028	Short-chain dehydrogenase reductase Sdr
E3399_RS10730	COG1309	transcriptional regulator
E3399_RS10765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E3399_RS10785	COG0668	transmembrane transport
E3399_RS10790	COG3182	Iron-regulated membrane protein
E3399_RS10810	COG2840	Smr protein MutS2
E3399_RS10815	COG0840	transmembrane signaling receptor activity
E3399_RS10830	COG0513	Belongs to the DEAD box helicase family
E3399_RS10845	COG2076	Multidrug Resistance protein
E3399_RS10855	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3399_RS10855	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3399_RS10855	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3399_RS10855	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3399_RS10865	COG3042	response to heat
E3399_RS10870	COG3187	Heat shock protein
E3399_RS10875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E3399_RS10880	COG2911	Protein conserved in bacteria
E3399_RS10890	COG3784	Protein of unknown function (DUF1318)
E3399_RS10905	COG1643	Atp-dependent helicase
E3399_RS10910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E3399_RS10915	COG3038	cytochrome b561
E3399_RS10920	COG0500	methyltransferase
E3399_RS10930	COG0765	amino acid transport
E3399_RS10940	COG0765	amino acid transport
E3399_RS10945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3399_RS10980	COG0840	transmembrane signaling receptor activity
E3399_RS10985	COG0583	DNA-binding transcription factor activity
E3399_RS10990	COG5383	Protein conserved in bacteria
E3399_RS10995	COG2272	Belongs to the type-B carboxylesterase lipase family
E3399_RS11000	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
E3399_RS11005	COG2353	YceI-like domain
E3399_RS11010	COG1304	FMN binding
E3399_RS11020	COG1349	DNA-binding transcription factor activity
E3399_RS11025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3399_RS11030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS11035	COG0434	BtpA family
E3399_RS11040	COG3775	system Galactitol-specific IIC component
E3399_RS11045	COG3414	Phosphotransferase system galactitol-specific IIB component
E3399_RS11055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3399_RS11060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E3399_RS11065	COG1275	C4-dicarboxylate transporter malic acid transport protein
E3399_RS11070	COG0500	methyltransferase
E3399_RS11080	COG3135	benzoate transporter
E3399_RS11085	COG1396	sequence-specific DNA binding
E3399_RS11090	COG0826	peptidase U32
E3399_RS11115	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E3399_RS11120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3399_RS11160	COG3238	Protein conserved in bacteria
E3399_RS11170	COG2130	NADP-dependent
E3399_RS11175	COG1802	Transcriptional regulator
E3399_RS11180	COG4772	TonB-dependent receptor
E3399_RS11185	COG3391	amine dehydrogenase activity
E3399_RS11220	COG2181	nitrate reductase activity
E3399_RS11225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E3399_RS11230	COG1140	nitrate reductase beta subunit
E3399_RS11235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3399_RS11275	COG0437	4 iron, 4 sulfur cluster binding
E3399_RS11280	COG2864	formate dehydrogenase
E3399_RS11285	COG1064	alcohol dehydrogenase
E3399_RS11305	COG1764	response to oxidative stress
E3399_RS11320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E3399_RS11335	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E3399_RS11340	COG1757	Na H antiporter
E3399_RS11345	COG1609	Transcriptional regulator
E3399_RS11390	COG0251	oxidation-reduction process
E3399_RS11395	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E3399_RS11420	COG2271	Major facilitator Superfamily
E3399_RS11425	COG1063	alcohol dehydrogenase
E3399_RS11430	COG2186	Transcriptional regulator
E3399_RS11440	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3399_RS11445	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E3399_RS11470	COG1773	rubredoxin
E3399_RS11495	COG3781	membrane
E3399_RS11510	COG1012	belongs to the aldehyde dehydrogenase family
E3399_RS11515	COG0583	DNA-binding transcription factor activity
E3399_RS11550	COG2814	Major facilitator Superfamily
E3399_RS11560	COG3111	PFAM Bacterial OB fold (BOF) protein
E3399_RS11565	COG1546	Belongs to the CinA family
E3399_RS11570	COG3729	General stress protein
E3399_RS11585	COG4221	oxidoreductase activity
E3399_RS11590	COG1802	Transcriptional regulator
E3399_RS11600	COG0246	Mannitol dehydrogenase
E3399_RS11605	COG0477	Major facilitator Superfamily
E3399_RS11610	COG1063	alcohol dehydrogenase
E3399_RS11630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3399_RS11645	COG0243	molybdopterin cofactor binding
E3399_RS11650	COG0243	molybdopterin cofactor binding
E3399_RS11655	COG0437	4 iron, 4 sulfur cluster binding
E3399_RS11660	COG3302	dmso reductase anchor subunit
E3399_RS11700	COG1940	carbohydrate kinase activity
E3399_RS11705	COG0583	DNA-binding transcription factor activity
E3399_RS11710	COG2814	Major facilitator Superfamily
E3399_RS11720	COG3591	Belongs to the peptidase S1B family
E3399_RS11740	COG0628	permease
E3399_RS11745	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E3399_RS11750	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E3399_RS11760	COG0531	amino acid
E3399_RS11765	COG3136	membrane protein required for alginate biosynthesis
E3399_RS11770	COG0745	RESPONSE REGULATOR receiver
E3399_RS11780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3399_RS11785	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
E3399_RS11790	COG2205	protein histidine kinase activity
E3399_RS11815	COG5339	Protein conserved in bacteria
E3399_RS11825	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E3399_RS11835	COG0673	inositol 2-dehydrogenase activity
E3399_RS11885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3399_RS11895	COG0625	glutathione transferase activity
E3399_RS11915	COG3895	Periplasmic Protein
E3399_RS11940	COG1566	PFAM secretion protein HlyD family protein
E3399_RS11955	COG4989	oxidoreductase activity
E3399_RS11960	COG3313	Fe-S protein
E3399_RS11965	COG1309	transcriptional regulator
E3399_RS11970	COG1902	pentaerythritol trinitrate reductase activity
E3399_RS11990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E3399_RS11995	COG0791	NLP P60 protein
E3399_RS12015	COG0583	DNA-binding transcription factor activity
E3399_RS12020	COG2814	Major facilitator Superfamily
E3399_RS12025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E3399_RS12030	COG0307	riboflavin synthase, alpha
E3399_RS12210	COG0789	Transcriptional regulator
E3399_RS12215	COG3272	Protein of unknown function (DUF1722)
E3399_RS12250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS12260	COG2267	carboxylic ester hydrolase activity
E3399_RS12265	COG0531	amino acid
E3399_RS12285	COG4238	major outer membrane lipoprotein
E3399_RS12290	COG1376	ErfK ybiS ycfS ynhG family protein
E3399_RS12305	COG0719	Fe-S assembly protein
E3399_RS12310	COG0396	ATPase activity
E3399_RS12315	COG0719	Fe-S assembly protein
E3399_RS12320	COG0316	Belongs to the HesB IscA family
E3399_RS12325	COG1823	symporter activity
E3399_RS12335	COG2050	protein possibly involved in aromatic compounds catabolism
E3399_RS12340	COG0277	FAD linked oxidase domain protein
E3399_RS12340	COG0247	lactate metabolic process
E3399_RS12345	COG0628	permease
E3399_RS12360	COG0738	Major facilitator superfamily
E3399_RS12365	COG2271	Major facilitator Superfamily
E3399_RS12380	COG4670	ketone body catabolic process
E3399_RS12385	COG1960	acyl-CoA dehydrogenase activity
E3399_RS12390	COG1917	Cupin 2, conserved barrel domain protein
E3399_RS12390	COG2207	Transcriptional regulator
E3399_RS12395	COG2086	electron transfer activity
E3399_RS12400	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E3399_RS12405	COG0644	oxidoreductase
E3399_RS12410	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3399_RS12415	COG0318	PFAM AMP-dependent synthetase and ligase
E3399_RS12420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3399_RS12420	COG0574	Belongs to the PEP-utilizing enzyme family
E3399_RS12435	COG4256	Hemin uptake protein
E3399_RS12450	COG0791	NLP P60 protein
E3399_RS12460	COG0386	Belongs to the glutathione peroxidase family
E3399_RS12525	COG3137	Salt-induced outer membrane protein
E3399_RS12530	COG1105	Belongs to the carbohydrate kinase PfkB family
E3399_RS12540	COG3001	Fructosamine kinase
E3399_RS12550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3399_RS12555	COG1988	membrane-bound metal-dependent
E3399_RS12560	COG1823	symporter activity
E3399_RS12570	COG0753	catalase activity
E3399_RS12580	COG1486	melibiose metabolic process
E3399_RS12585	COG1917	Cupin 2, conserved barrel domain protein
E3399_RS12585	COG2169	Transcriptional regulator
E3399_RS12590	COG1447	Phosphotransferase system cellobiose-specific component IIA
E3399_RS12595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E3399_RS12600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E3399_RS12610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3399_RS12620	COG0322	excinuclease ABC activity
E3399_RS12625	COG3678	ATP-independent chaperone mediated protein folding
E3399_RS12660	COG0494	nUDIX hydrolase
E3399_RS12675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E3399_RS12685	COG0778	Nitroreductase
E3399_RS12690	COG0616	signal peptide processing
E3399_RS12695	COG0252	asparaginase activity
E3399_RS12700	COG1335	isochorismatase
E3399_RS12705	COG2814	Major facilitator Superfamily
E3399_RS12710	COG1349	DNA-binding transcription factor activity
E3399_RS12715	COG0667	Aldo Keto reductase
E3399_RS12720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS12725	COG0191	fructose-bisphosphate aldolase activity
E3399_RS12730	COG1063	alcohol dehydrogenase
E3399_RS12735	COG2271	Major facilitator Superfamily
E3399_RS12740	COG1063	alcohol dehydrogenase
E3399_RS12745	COG3139	Protein of unknown function (DUF1315)
E3399_RS12765	COG0656	L-ascorbic acid biosynthetic process
E3399_RS12770	COG0641	radical SAM
E3399_RS12775	COG3713	MltA-interacting MipA family protein
E3399_RS12780	COG2766	serine protein kinase
E3399_RS12795	COG2199	diguanylate cyclase activity
E3399_RS12800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3399_RS12815	COG2207	Transcriptional regulator
E3399_RS12820	COG2807	transmembrane transport
E3399_RS12825	COG3189	MarR family transcriptional regulator
E3399_RS12835	COG3042	response to heat
E3399_RS12845	COG2261	transglycosylase associated protein
E3399_RS12865	COG3615	Tellurite resistance protein tehB
E3399_RS12875	COG1605	Chorismate mutase
E3399_RS12890	COG0789	Transcriptional regulator
E3399_RS12905	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3399_RS12920	COG0668	transmembrane transport
E3399_RS12925	COG1124	(ABC) transporter
E3399_RS12955	COG3038	cytochrome b561
E3399_RS12970	COG0071	Belongs to the small heat shock protein (HSP20) family
E3399_RS13040	COG0538	isocitrate dehydrogenase activity
E3399_RS13045	COG1187	pseudouridine synthase activity
E3399_RS13070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E3399_RS13085	COG2850	peptidyl-arginine hydroxylation
E3399_RS13115	COG1177	transmembrane transport
E3399_RS13135	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3399_RS13140	COG1136	(ABC) transporter
E3399_RS13145	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3399_RS13150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E3399_RS13155	COG1388	LysM domain
E3399_RS13155	COG1376	ErfK ybiS ycfS ynhG family protein
E3399_RS13165	COG1309	transcriptional regulator
E3399_RS13170	COG3134	Outer membrane lipoprotein
E3399_RS13175	COG1252	NADH dehydrogenase
E3399_RS13200	COG5633	Lipoprotein
E3399_RS13205	COG0537	adenosine 5'-monophosphoramidase activity
E3399_RS13210	COG4773	Receptor
E3399_RS13220	COG0084	hydrolase, TatD family'
E3399_RS13225	COG0470	DNA polymerase III
E3399_RS13235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E3399_RS13240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E3399_RS13245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3399_RS13310	COG1530	ribonuclease E activity
E3399_RS13400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3399_RS13410	COG2999	glutathione oxidoreductase activity
E3399_RS13445	COG3038	cytochrome b561
E3399_RS13460	COG1560	Kdo2-lipid A biosynthetic process
E3399_RS13475	COG5645	(Lipo)protein
E3399_RS13500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3399_RS13555	COG3381	protein complex oligomerization
E3399_RS13580	COG0673	inositol 2-dehydrogenase activity
E3399_RS13585	COG2814	Major facilitator Superfamily
E3399_RS13605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3399_RS13610	COG1737	Transcriptional regulator
E3399_RS13615	COG1702	phosphate starvation-inducible protein PhoH
E3399_RS13635	COG1309	transcriptional regulator
E3399_RS13640	COG3729	General stress protein
E3399_RS13660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3399_RS13665	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E3399_RS13665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3399_RS13670	COG4232	protein-disulfide reductase activity
E3399_RS13720	COG3971	2-oxopent-4-enoate hydratase activity
E3399_RS13730	COG3384	dioxygenase
E3399_RS13735	COG1012	belongs to the aldehyde dehydrogenase family
E3399_RS13745	COG1846	Transcriptional regulator
E3399_RS13750	COG2368	4-hydroxyphenylacetate
E3399_RS13765	COG0745	RESPONSE REGULATOR receiver
E3399_RS13770	COG2205	protein histidine kinase activity
E3399_RS13820	COG0670	Belongs to the BI1 family
E3399_RS13840	COG1881	PFAM PEBP family protein
E3399_RS13855	COG1832	CoA-binding protein
E3399_RS13870	COG0210	DNA helicase
E3399_RS13875	COG3304	Inner membrane component domain
E3399_RS13880	COG1289	transmembrane transporter activity
E3399_RS13885	COG3070	regulator of competence-specific genes
E3399_RS13905	COG1067	ATP-dependent peptidase activity
E3399_RS13915	COG3130	regulation of translation
E3399_RS13920	COG3009	Protein conserved in bacteria
E3399_RS13925	COG3008	intermembrane lipid transfer
E3399_RS13925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3399_RS13930	COG2995	paraquat-inducible protein a
E3399_RS13935	COG0488	(ABC) transporter
E3399_RS13945	COG3217	Mosc domain protein beta barrel domain protein
E3399_RS13945	COG0633	Ferredoxin
E3399_RS13960	COG0308	aminopeptidase N
E3399_RS13990	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3399_RS14100	COG4220	transposase activity
E3399_RS14140	COG0484	heat shock protein binding
E3399_RS14180	COG1484	DNA-dependent DNA replication
E3399_RS14225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3399_RS14245	COG0582	viral genome integration into host DNA
E3399_RS14255	COG1115	amino acid carrier protein
E3399_RS14270	COG1522	sequence-specific DNA binding
E3399_RS14275	COG0017	Asparaginyl-tRNA synthetase
E3399_RS14280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3399_RS14290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3399_RS14295	COG3108	Peptidase M15
E3399_RS14300	COG2989	Protein conserved in bacteria
E3399_RS14315	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E3399_RS14325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3399_RS14330	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E3399_RS14335	COG3173	Aminoglycoside phosphotransferase
E3399_RS14355	COG3214	Protein conserved in bacteria
E3399_RS14370	COG0658	competence protein
E3399_RS14370	COG2333	competence protein COMEC
E3399_RS14380	COG0539	negative regulation of cytoplasmic translation
E3399_RS14390	COG0501	Belongs to the peptidase M48B family
E3399_RS14405	COG2323	membrane
E3399_RS14410	COG1944	ATP diphosphatase activity
E3399_RS14415	COG2116	formate transmembrane transporter activity
E3399_RS14435	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3399_RS14440	COG0531	amino acid
E3399_RS14450	COG3302	dmso reductase anchor subunit
E3399_RS14455	COG0437	4 iron, 4 sulfur cluster binding
E3399_RS14460	COG0243	molybdopterin cofactor binding
E3399_RS14470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3399_RS14490	COG0492	ferredoxin-NADP+ reductase activity
E3399_RS14495	COG4988	ABC transporter
E3399_RS14500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3399_RS14520	COG0583	DNA-binding transcription factor activity
E3399_RS14530	COG1335	isochorismatase
E3399_RS14545	COG0542	response to heat
E3399_RS14555	COG1278	Cold shock
E3399_RS14565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3399_RS14570	COG2990	Protein conserved in bacteria
E3399_RS14575	COG3593	DNA synthesis involved in DNA repair
E3399_RS14580	COG2431	L-lysine efflux transmembrane transporter activity
E3399_RS14590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3399_RS14595	COG0028	Belongs to the TPP enzyme family
E3399_RS14600	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E3399_RS14605	COG0702	epimerase
E3399_RS14610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3399_RS14615	COG3023	N-Acetylmuramoyl-L-alanine amidase
E3399_RS14630	COG1126	abc transporter atp-binding protein
E3399_RS14635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3399_RS14640	COG4215	(ABC) transporter
E3399_RS14645	COG4160	amino acid transport
E3399_RS14650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3399_RS14680	COG1177	transmembrane transport
E3399_RS14685	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3399_RS14690	COG3842	ATPase activity
E3399_RS14695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3399_RS14740	COG3226	Transcriptional regulator
E3399_RS14745	COG0738	Major facilitator superfamily
E3399_RS14750	COG0561	phosphatase activity
E3399_RS14755	COG2814	Major facilitator Superfamily
E3399_RS14760	COG0671	phosphoesterase, PA-phosphatase related
E3399_RS14765	COG1349	DNA-binding transcription factor activity
E3399_RS14775	COG0625	glutathione transferase activity
E3399_RS14780	COG2133	pyrroloquinoline quinone binding
E3399_RS14790	COG2610	gluconate transmembrane transporter activity
E3399_RS14795	COG0583	DNA-binding transcription factor activity
E3399_RS14810	COG1960	acyl-CoA dehydrogenase activity
E3399_RS14830	COG2301	Belongs to the HpcH HpaI aldolase family
E3399_RS14880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3399_RS14885	COG1882	Formate acetyltransferase
E3399_RS14890	COG0561	phosphatase activity
E3399_RS14900	COG0488	(ABC) transporter
E3399_RS14905	COG1376	ErfK ybiS ycfS ynhG family protein
E3399_RS14910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E3399_RS14925	COG2194	sulfuric ester hydrolase activity
E3399_RS14930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E3399_RS14945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3399_RS14950	COG0765	amino acid transport
E3399_RS14955	COG1126	abc transporter atp-binding protein
E3399_RS14960	COG0668	transmembrane transport
E3399_RS14970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3399_RS14980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3399_RS14990	COG0513	Belongs to the DEAD box helicase family
E3399_RS14995	COG1309	transcriptional regulator
E3399_RS15005	COG1131	(ABC) transporter
E3399_RS15010	COG0842	Transport permease protein
E3399_RS15015	COG0842	Transport permease protein
E3399_RS15025	COG3568	Endonuclease Exonuclease Phosphatase
E3399_RS15030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3399_RS15035	COG0392	lysyltransferase activity
E3399_RS15055	COG0670	Belongs to the BI1 family
E3399_RS15065	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E3399_RS15075	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3399_RS15135	COG1881	PFAM PEBP family protein
E3399_RS15165	COG4677	pectinesterase activity
E3399_RS15175	COG0561	phosphatase activity
E3399_RS15185	COG4149	molybdate abc transporter
E3399_RS15190	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3399_RS15200	COG2005	Transcriptional regulator
E3399_RS15200	COG3585	molybdate ion transport
E3399_RS15205	COG1119	ATPase activity
E3399_RS15230	COG2017	converts alpha-aldose to the beta-anomer
E3399_RS15240	COG1120	ATPase activity
E3399_RS15245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3399_RS15260	COG5016	pyruvate
E3399_RS15260	COG0511	ligase activity, forming carbon-carbon bonds
E3399_RS15270	COG0471	metal ion transport
E3399_RS15270	COG0490	domain, Protein
E3399_RS15275	COG0583	DNA-binding transcription factor activity
E3399_RS15280	COG0583	DNA-binding transcription factor activity
E3399_RS15290	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3399_RS15290	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3399_RS15295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E3399_RS15305	COG1230	cation diffusion facilitator family transporter
E3399_RS15345	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E3399_RS15350	COG2885	chlorophyll binding
E3399_RS15360	COG3064	Membrane
E3399_RS15365	COG0848	biopolymer transport protein
E3399_RS15370	COG0811	peptide transport
E3399_RS15375	COG0824	Thioesterase
E3399_RS15380	COG3790	cyd operon protein YbgE
E3399_RS15385	COG4890	Cyd operon protein YbgT
E3399_RS15390	COG1294	oxidase, subunit
E3399_RS15395	COG1271	oxidase subunit
E3399_RS15400	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3399_RS15410	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3399_RS15415	COG0567	Dehydrogenase, E1 component
E3399_RS15430	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E3399_RS15445	COG3180	Ammonia monooxygenase
E3399_RS15460	COG1984	allophanate hydrolase subunit 2
E3399_RS15465	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3399_RS15495	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
E3399_RS15505	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
E3399_RS15510	COG2205	protein histidine kinase activity
E3399_RS15515	COG0745	RESPONSE REGULATOR receiver
E3399_RS15525	COG1982	Orn Lys Arg decarboxylase major
E3399_RS15530	COG0531	amino acid
E3399_RS15540	COG0033	Phosphoglucomutase
E3399_RS15550	COG0596	Alpha beta hydrolase
E3399_RS15565	COG0735	belongs to the Fur family
E3399_RS15570	COG0583	DNA-binding transcription factor activity
E3399_RS15575	COG1053	succinate dehydrogenase
E3399_RS15615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3399_RS15620	COG1940	carbohydrate kinase activity
E3399_RS15620	COG1846	Transcriptional regulator
E3399_RS15625	COG0647	UMP catabolic process
E3399_RS15630	COG0367	asparagine synthase
E3399_RS15670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3399_RS15680	COG1702	phosphate starvation-inducible protein PhoH
E3399_RS15705	COG0765	amino acid transport
E3399_RS15710	COG0765	amino acid transport
E3399_RS15715	COG1126	abc transporter atp-binding protein
E3399_RS15730	COG0443	Heat shock 70 kDa protein
E3399_RS15735	COG2214	Heat shock protein DnaJ domain protein
E3399_RS15745	COG2214	Heat shock protein DnaJ domain protein
E3399_RS15760	COG2888	peptidyl-tyrosine sulfation
E3399_RS15765	COG3829	transcription factor binding
E3399_RS15765	COG3290	protein histidine kinase activity
E3399_RS15795	COG1466	dna polymerase III delta subunit
E3399_RS15805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3399_RS15815	COG0799	negative regulation of ribosome biogenesis
E3399_RS15825	COG0768	penicillin binding
E3399_RS15830	COG0772	Belongs to the SEDS family
E3399_RS15840	COG1686	Belongs to the peptidase S11 family
E3399_RS15855	COG0583	DNA-binding transcription factor activity
E3399_RS15870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3399_RS15890	COG3069	C4-dicarboxylate transmembrane transporter activity
E3399_RS15895	COG4565	transcriptional regulatory protein
E3399_RS15900	COG3290	protein histidine kinase activity
E3399_RS15905	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E3399_RS15915	COG2301	Belongs to the HpcH HpaI aldolase family
E3399_RS15920	COG3051	citrate lyase alpha subunit
E3399_RS15935	COG0471	metal ion transport
E3399_RS15940	COG3719	Belongs to the RNase T2 family
E3399_RS15945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3399_RS15950	COG1063	alcohol dehydrogenase
E3399_RS15970	COG0243	molybdopterin cofactor binding
E3399_RS15990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3399_RS16000	COG3969	phosphoadenosine phosphosulfate
E3399_RS16005	COG1475	DNA binding
E3399_RS16010	COG0436	Aminotransferase
E3399_RS16015	COG0371	Dehydrogenase
E3399_RS16020	COG2879	small protein
E3399_RS16025	COG1966	Carbon starvation protein
E3399_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
E3399_RS16040	COG1535	isochorismatase
E3399_RS16040	COG3433	isochorismatase activity
E3399_RS16045	COG1021	2,3-dihydroxybenzoate-AMP ligase
E3399_RS16050	COG1169	isochorismate synthase
E3399_RS16055	COG4592	Periplasmic binding protein
E3399_RS16065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3399_RS16070	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3399_RS16075	COG1120	ATPase activity
E3399_RS16080	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E3399_RS16085	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E3399_RS16085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E3399_RS16090	COG3251	PFAM MbtH domain protein
E3399_RS16095	COG2382	esterase
E3399_RS16100	COG4771	TonB-dependent receptor
E3399_RS16130	COG2315	Protein conserved in bacteria
E3399_RS16155	COG3716	PTS system mannose fructose sorbose family IID component
E3399_RS16165	COG2222	sugar isomerase
E3399_RS16170	COG3933	PFAM sigma-54 factor interaction domain-containing protein
E3399_RS16170	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E3399_RS16180	COG0668	transmembrane transport
E3399_RS16185	COG1113	amino acid transport
E3399_RS16195	COG3059	membrane
E3399_RS16205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3399_RS16210	COG2207	Transcriptional regulator
E3399_RS16215	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3399_RS16220	COG5002	protein histidine kinase activity
E3399_RS16230	COG2246	polysaccharide biosynthetic process
E3399_RS16235	COG0463	Glycosyl transferase, family 2
E3399_RS16260	COG0463	Glycosyl transferase, family 2
E3399_RS16265	COG2246	polysaccharide biosynthetic process
E3399_RS16280	COG0582	viral genome integration into host DNA
E3399_RS16355	COG2501	S4 domain
E3399_RS16360	COG1988	membrane-bound metal-dependent
E3399_RS16380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E3399_RS16390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3399_RS16395	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E3399_RS16400	COG0549	Belongs to the carbamate kinase family
E3399_RS16410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3399_RS16415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3399_RS16420	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E3399_RS16425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3399_RS16430	COG3257	ureidoglycine aminohydrolase activity
E3399_RS16435	COG1929	Belongs to the glycerate kinase type-1 family
E3399_RS16440	COG2233	PERMEase
E3399_RS16450	COG1953	Uracil, thiamine, allantoin
E3399_RS16460	COG2084	Dehydrogenase
E3399_RS16465	COG3622	Belongs to the hyi family
E3399_RS16470	COG3960	tartronate-semialdehyde synthase activity
E3399_RS16505	COG1464	Belongs to the NlpA lipoprotein family
E3399_RS16515	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E3399_RS16520	COG4181	ATPase activity
E3399_RS16525	COG2755	lipolytic protein G-D-S-L family
E3399_RS16530	COG0300	oxidoreductase activity
E3399_RS16535	COG3118	belongs to the thioredoxin family
E3399_RS16540	COG0390	transport system, permease component
E3399_RS16545	COG4619	ABC transporter
E3399_RS16550	COG0330	HflC and HflK could
E3399_RS16555	COG1585	Membrane protein implicated in regulation of membrane protease activity
E3399_RS16565	COG2217	Heavy metal translocating P-type atpase
E3399_RS16575	COG3735	TraB family
E3399_RS16590	COG2223	nitrite transmembrane transporter activity
E3399_RS16595	COG4651	solute:proton antiporter activity
E3399_RS16595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E3399_RS16600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS16645	COG2832	Protein of unknown function (DUF454)
E3399_RS16650	COG3923	Primosomal replication protein n
E3399_RS16660	COG5464	transposase or invertase
E3399_RS16665	COG1196	nuclear chromosome segregation
E3399_RS16665	COG3264	Mechanosensitive ion channel
E3399_RS16670	COG1309	transcriptional regulator
E3399_RS16675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3399_RS16680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3399_RS16695	COG0110	maltose O-acetyltransferase activity
E3399_RS16715	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E3399_RS16725	COG3695	enzyme binding
E3399_RS16730	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E3399_RS16735	COG1946	Acyl-CoA thioesterase
E3399_RS16740	COG0004	ammonium transporteR
E3399_RS16745	COG0347	Belongs to the P(II) protein family
E3399_RS16750	COG1132	(ABC) transporter
E3399_RS16755	COG1132	(ABC) transporter
E3399_RS16760	COG1522	sequence-specific DNA binding
E3399_RS16775	COG4533	DNA binding
E3399_RS16785	COG0824	Thioesterase
E3399_RS16790	COG1555	photosystem II stabilization
E3399_RS16795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3399_RS16805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E3399_RS16830	COG0271	Belongs to the BolA IbaG family
E3399_RS16835	COG3056	Lipoprotein
E3399_RS16840	COG2223	nitrite transmembrane transporter activity
E3399_RS16845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E3399_RS16850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E3399_RS16855	COG1845	cytochrome c oxidase, subunit III
E3399_RS16860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E3399_RS16880	COG2814	Major facilitator Superfamily
E3399_RS16910	COG2188	Transcriptional regulator
E3399_RS16945	COG0142	geranyltranstransferase activity
E3399_RS16955	COG0667	Aldo Keto reductase
E3399_RS16960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E3399_RS16965	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E3399_RS16980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3399_RS16980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3399_RS16990	COG4238	major outer membrane lipoprotein
E3399_RS17025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3399_RS17035	COG1862	Preprotein translocase
E3399_RS17055	COG0450	alkyl hydroperoxide reductase
E3399_RS17060	COG0366	Alpha amylase catalytic
E3399_RS17075	COG5002	protein histidine kinase activity
E3399_RS17085	COG0420	3'-5' exonuclease activity
E3399_RS17090	COG0419	ATPase involved in DNA repair
E3399_RS17095	COG2814	Major facilitator Superfamily
E3399_RS17100	COG1940	carbohydrate kinase activity
E3399_RS17115	COG4126	flavin adenine dinucleotide binding
E3399_RS17135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E3399_RS17140	COG3706	GGDEF domain
E3399_RS17185	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E3399_RS17195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3399_RS17210	COG0113	porphobilinogen synthase activity
E3399_RS17245	COG1280	lysine exporter protein (LysE YggA)
E3399_RS17265	COG1294	oxidase, subunit
E3399_RS17270	COG1271	oxidase subunit
E3399_RS17290	COG2814	Major facilitator Superfamily
E3399_RS17300	COG0789	Transcriptional regulator
E3399_RS17310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3399_RS17355	COG2200	EAL domain
E3399_RS17370	COG3539	Fimbrial protein
E3399_RS17375	COG3121	Chaperone
E3399_RS17380	COG3188	usher protein
E3399_RS17415	COG0179	Fumarylacetoacetate (FAA) hydrolase
E3399_RS17430	COG2814	Major facilitator Superfamily
E3399_RS17455	COG0582	viral genome integration into host DNA
E3399_RS17495	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3399_RS17500	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E3399_RS17505	COG1690	Belongs to the RtcB family
E3399_RS17515	COG3034	peptidoglycan biosynthetic process
E3399_RS17520	COG0121	glutamine amidotransferase
E3399_RS17535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3399_RS17565	COG1522	sequence-specific DNA binding
E3399_RS17665	COG4983	Phage plasmid primase, P4 family domain protein
E3399_RS17695	COG3596	GTP binding
E3399_RS17705	COG2378	regulation of single-species biofilm formation
E3399_RS17715	COG2378	regulation of single-species biofilm formation
E3399_RS17760	COG2003	Belongs to the UPF0758 family
E3399_RS17825	COG2226	methyltransferase
E3399_RS17835	COG1388	LysM domain
E3399_RS17835	COG0741	lytic transglycosylase activity
E3399_RS17840	COG2226	methyltransferase
E3399_RS17850	COG2814	Major facilitator Superfamily
E3399_RS17855	COG0583	DNA-binding transcription factor activity
E3399_RS17895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3399_RS17920	COG1720	tRNA m6t6A37 methyltransferase activity
E3399_RS17930	COG3015	lipoprotein NlpE involved in copper resistance
E3399_RS17935	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E3399_RS17950	COG4568	rho-dependent transcription termination
E3399_RS17960	COG0346	lactoylglutathione lyase activity
E3399_RS17965	COG1982	Orn Lys Arg decarboxylase major
E3399_RS18025	COG0575	Belongs to the CDS family
E3399_RS18075	COG0477	Major facilitator Superfamily
E3399_RS18085	COG3835	regulator
E3399_RS18110	COG2860	membrane
E3399_RS18140	COG3539	Fimbrial protein
E3399_RS18145	COG3539	Fimbrial protein
E3399_RS18150	COG3121	Chaperone
E3399_RS18155	COG3188	usher protein
E3399_RS18175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3399_RS18180	COG1120	ATPase activity
E3399_RS18185	COG4774	siderophore transport
E3399_RS18190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3399_RS18195	COG1643	Atp-dependent helicase
E3399_RS18200	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E3399_RS18225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3399_RS18250	COG3121	Chaperone
E3399_RS18255	COG3188	usher protein
E3399_RS18260	COG3539	Fimbrial protein
E3399_RS18280	COG0726	polysaccharide deacetylase
E3399_RS18285	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS18305	COG3539	Fimbrial protein
E3399_RS18310	COG0842	Transport permease protein
E3399_RS18315	COG1131	(ABC) transporter
E3399_RS18320	COG0288	reversible hydration of carbon dioxide
E3399_RS18330	COG4993	Dehydrogenase
E3399_RS18335	COG2132	Multicopper oxidase
E3399_RS18355	COG1349	DNA-binding transcription factor activity
E3399_RS18425	COG3064	Membrane
E3399_RS18440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3399_RS18445	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3399_RS18450	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E3399_RS18465	COG2211	Major facilitator Superfamily
E3399_RS18470	COG3940	Belongs to the glycosyl hydrolase 43 family
E3399_RS18475	COG3725	Membrane protein required for beta-lactamase induction
E3399_RS18495	COG4969	Belongs to the N-Me-Phe pilin family
E3399_RS18500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3399_RS18505	COG1459	type II secretion system
E3399_RS18540	COG0494	nUDIX hydrolase
E3399_RS18560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3399_RS18565	COG0849	cell division
E3399_RS18590	COG0772	Belongs to the SEDS family
E3399_RS18605	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3399_RS18615	COG0768	penicillin binding
E3399_RS18705	COG0586	Pfam SNARE associated Golgi protein
E3399_RS18745	COG0417	DNA replication proofreading
E3399_RS18775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E3399_RS18810	COG3119	arylsulfatase activity
E3399_RS18835	COG2271	Major facilitator Superfamily
E3399_RS18840	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3399_RS18845	COG0644	oxidoreductase
E3399_RS18995	COG1047	Peptidyl-prolyl cis-trans
E3399_RS19010	COG0196	riboflavin kinase activity
E3399_RS19035	COG0583	DNA-binding transcription factor activity
E3399_RS19055	COG0641	radical SAM
E3399_RS19060	COG3119	arylsulfatase activity
E3399_RS19070	COG0737	Belongs to the 5'-nucleotidase family
E3399_RS19085	COG0583	DNA-binding transcription factor activity
E3399_RS19105	COG3121	Chaperone
E3399_RS19110	COG3539	Fimbrial protein
E3399_RS19125	COG3188	usher protein
E3399_RS19190	COG4735	regulation of single-species biofilm formation
E3399_RS19195	COG1584	GPR1 FUN34 yaaH family protein
E3399_RS19200	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3399_RS19210	COG1115	amino acid carrier protein
E3399_RS19220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3399_RS19230	COG0527	aspartate kinase activity
E3399_RS19230	COG0460	homoserine dehydrogenase
E3399_RS19240	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E3399_RS19250	COG0745	RESPONSE REGULATOR receiver
E3399_RS19270	COG3121	Chaperone
E3399_RS19290	COG4452	Inner membrane protein CreD
E3399_RS19295	COG2205	protein histidine kinase activity
E3399_RS19300	COG0745	RESPONSE REGULATOR receiver
E3399_RS19305	COG3045	CreA protein
E3399_RS19310	COG3708	Transcriptional regulator
E3399_RS19310	COG2207	Transcriptional regulator
E3399_RS19335	COG0488	(ABC) transporter
E3399_RS19350	COG0560	Phosphoserine phosphatase
E3399_RS19355	COG3726	membrane protein affecting hemolysin expression
E3399_RS19370	COG3539	Fimbrial protein
E3399_RS19375	COG3121	Chaperone
E3399_RS19380	COG3188	usher protein
E3399_RS19410	COG1328	CTP reductase activity
E3399_RS19415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3399_RS19420	COG0084	hydrolase, TatD family'
E3399_RS19425	COG4667	esterase of the alpha-beta hydrolase superfamily
E3399_RS19435	COG2823	Periplasmic or secreted lipoprotein
E3399_RS19445	COG1011	Hydrolase
E3399_RS19455	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E3399_RS19485	COG3706	GGDEF domain
E3399_RS19490	COG4114	ferric iron reductase
E3399_RS19495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3399_RS19500	COG2197	response regulator
E3399_RS19505	COG2197	response regulator
E3399_RS19510	COG2966	Psort location CytoplasmicMembrane, score
E3399_RS19525	COG1484	DNA-dependent DNA replication
E3399_RS19540	COG0840	transmembrane signaling receptor activity
E3399_RS19545	COG1966	Carbon starvation protein
E3399_RS19550	COG2879	small protein
E3399_RS19555	COG0523	cobalamin synthesis protein
E3399_RS19600	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E3399_RS19605	COG0732	type I restriction modification DNA specificity domain
E3399_RS19610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
E3399_RS19615	COG3586	endonuclease activity
E3399_RS19630	COG1012	belongs to the aldehyde dehydrogenase family
E3399_RS19635	COG5464	transposase or invertase
E3399_RS19645	COG2733	membrane
E3399_RS19650	COG0477	Major facilitator Superfamily
E3399_RS19655	COG3366	ferrous iron transmembrane transporter activity
E3399_RS19660	COG0700	Nucleoside recognition
E3399_RS19665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3399_RS19670	COG0583	DNA-binding transcription factor activity
E3399_RS19690	COG2186	Transcriptional regulator
E3399_RS19695	COG0412	Dienelactone hydrolase
E3399_RS19725	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3399_RS19820	COG0582	viral genome integration into host DNA
E3399_RS19830	COG1064	alcohol dehydrogenase
E3399_RS19835	COG3265	gluconokinase activity
E3399_RS19840	COG1063	alcohol dehydrogenase
E3399_RS19845	COG1028	Short-chain dehydrogenase reductase Sdr
E3399_RS19850	COG2610	gluconate transmembrane transporter activity
E3399_RS19855	COG1609	Transcriptional regulator
E3399_RS19860	COG0795	lipopolysaccharide-transporting ATPase activity
E3399_RS19865	COG0795	lipopolysaccharide-transporting ATPase activity
E3399_RS19875	COG2927	DNA polymerase III (CHI subunit)
E3399_RS19915	COG2731	YhcH YjgK YiaL family protein
E3399_RS19935	COG1288	antiporter activity
E3399_RS19940	COG1438	arginine binding
E3399_RS19985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3399_RS19985	COG1263	PTS System
E3399_RS19990	COG0366	Alpha amylase catalytic
E3399_RS20005	COG2026	Addiction module toxin, RelE StbE family
E3399_RS20010	COG3077	Addiction module antitoxin, RelB DinJ family
E3399_RS20015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS20015	COG3711	transcriptional antiterminator
E3399_RS20030	COG3964	amidohydrolase
E3399_RS20065	COG0312	modulator of DNA gyrase
E3399_RS20075	COG1082	Xylose isomerase domain protein TIM barrel
E3399_RS20085	COG2814	Major facilitator Superfamily
E3399_RS20090	COG0673	inositol 2-dehydrogenase activity
E3399_RS20095	COG3962	Belongs to the TPP enzyme family
E3399_RS20100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS20110	COG1082	Xylose isomerase domain protein TIM barrel
E3399_RS20115	COG5520	Belongs to the glycosyl hydrolase 30 family
E3399_RS20145	COG3718	enzyme involved in inositol metabolism
E3399_RS20150	COG0477	Major facilitator Superfamily
E3399_RS20150	COG2814	Major facilitator Superfamily
E3399_RS20155	COG0477	Major facilitator Superfamily
E3399_RS20155	COG2814	Major facilitator Superfamily
E3399_RS20160	COG0837	glucose binding
E3399_RS20160	COG1737	Transcriptional regulator
E3399_RS20165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E3399_RS20180	COG3964	amidohydrolase
E3399_RS20185	COG2271	Major facilitator Superfamily
E3399_RS20190	COG2105	PFAM AIG2 family protein
E3399_RS20210	COG1253	flavin adenine dinucleotide binding
E3399_RS20220	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E3399_RS20235	COG1733	regulation of RNA biosynthetic process
E3399_RS20240	COG0702	epimerase
E3399_RS20245	COG0697	spore germination
E3399_RS20255	COG1113	amino acid transport
E3399_RS20260	COG0545	Peptidyl-prolyl cis-trans isomerase
E3399_RS20265	COG3061	Opacity-associated protein A
E3399_RS20280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E3399_RS20350	COG1073	alpha beta
E3399_RS20355	COG3650	response to hydrogen peroxide
E3399_RS20365	COG1960	acyl-CoA dehydrogenase activity
E3399_RS20370	COG0754	glutathionylspermidine amidase activity
E3399_RS20375	COG5463	Belongs to the UPF0441 family
E3399_RS20380	COG3766	membrane
E3399_RS20395	COG1842	Phage shock protein A
E3399_RS20400	COG3789	protein conserved in bacteria
E3399_RS20425	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E3399_RS20430	COG0330	HflC and HflK could
E3399_RS20435	COG0330	HflC and HflK could
E3399_RS20440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E3399_RS20465	COG0802	atpase or kinase
E3399_RS20470	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E3399_RS20470	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3399_RS20495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3399_RS20515	COG3264	Mechanosensitive ion channel
E3399_RS20515	COG1511	domain protein
E3399_RS20530	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
E3399_RS20535	COG1053	succinate dehydrogenase
E3399_RS20540	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3399_RS20570	COG5510	response to toxic substance
E3399_RS20610	COG0531	amino acid
E3399_RS20615	COG3030	protein affecting phage T7 exclusion by the F plasmid
E3399_RS20620	COG1027	Aspartate ammonia-lyase
E3399_RS20625	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3399_RS20640	COG1309	transcriptional regulator
E3399_RS20750	COG2197	response regulator
E3399_RS20775	COG3381	protein complex oligomerization
E3399_RS20780	COG3302	dmso reductase anchor subunit
E3399_RS20785	COG0437	4 iron, 4 sulfur cluster binding
E3399_RS20790	COG0243	molybdopterin cofactor binding
E3399_RS20795	COG3290	protein histidine kinase activity
E3399_RS20800	COG4565	transcriptional regulatory protein
E3399_RS20810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3399_RS20815	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3399_RS20815	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3399_RS20830	COG2169	Transcriptional regulator
E3399_RS20835	COG1982	Orn Lys Arg decarboxylase major
E3399_RS20840	COG2207	Transcriptional regulator
E3399_RS20845	COG0531	amino acid
E3399_RS20875	COG2824	Alkylphosphonate utilization operon protein PhnA
E3399_RS20880	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E3399_RS20900	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E3399_RS20905	COG1301	dicarboxylic acid transport
E3399_RS20910	COG4235	cytochrome complex assembly
E3399_RS20915	COG3088	subunit of a heme lyase
E3399_RS20920	COG1138	Cytochrome C-type biogenesis protein
E3399_RS20925	COG3301	Polysulphide reductase, NrfD
E3399_RS20930	COG0437	4 iron, 4 sulfur cluster binding
E3399_RS20935	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E3399_RS20945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3399_RS20950	COG3162	membrane
E3399_RS20960	COG1346	cytolysis
E3399_RS20965	COG1380	Effector of murein hydrolase LrgA
E3399_RS20970	COG0583	DNA-binding transcription factor activity
E3399_RS20975	COG0025	NhaP-type Na H and K H
E3399_RS20980	COG2252	PERMEase
E3399_RS21000	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E3399_RS21060	COG2315	Protein conserved in bacteria
E3399_RS21070	COG3700	Belongs to the class B bacterial acid phosphatase family
E3399_RS21100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3399_RS21110	COG0735	belongs to the Fur family
E3399_RS21125	COG0534	Mate efflux family protein
E3399_RS21135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E3399_RS21185	COG3833	ABC-type maltose transport systems, permease component
E3399_RS21195	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3399_RS21220	COG0527	aspartate kinase activity
E3399_RS21250	COG0561	phosphatase activity
E3399_RS21255	COG1349	DNA-binding transcription factor activity
E3399_RS21270	COG3122	Protein conserved in bacteria
E3399_RS21315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E3399_RS21420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3399_RS21425	COG2104	thiamine diphosphate biosynthetic process
E3399_RS21490	COG0250	Participates in transcription elongation, termination and antitermination
E3399_RS21600	COG0583	DNA-binding transcription factor activity
E3399_RS21640	COG2207	Transcriptional regulator
E3399_RS21645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3399_RS21650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3399_RS21655	COG1882	Formate acetyltransferase
E3399_RS21660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3399_RS21665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3399_RS21670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3399_RS21670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS21670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3399_RS21680	COG0371	Dehydrogenase
E3399_RS21685	COG3738	Protein conserved in bacteria
E3399_RS21700	COG0737	Belongs to the 5'-nucleotidase family
E3399_RS21715	COG0668	transmembrane transport
E3399_RS21720	COG0527	aspartate kinase activity
E3399_RS21720	COG0460	homoserine dehydrogenase
E3399_RS21725	COG0626	cystathionine gamma-synthase activity
E3399_RS21750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3399_RS21755	COG1609	Transcriptional regulator
E3399_RS21760	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3399_RS21775	COG1575	Belongs to the MenA family. Type 1 subfamily
E3399_RS21790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3399_RS21800	COG1494	fructose-1,6-bisphosphatase
E3399_RS21810	COG3152	Membrane
E3399_RS21865	COG1070	Carbohydrate kinase
E3399_RS21885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3399_RS21895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS21900	COG2211	Major facilitator Superfamily
E3399_RS21905	COG2134	cdp-diacylglycerol pyrophosphatase
E3399_RS21925	COG3678	ATP-independent chaperone mediated protein folding
E3399_RS21930	COG0745	RESPONSE REGULATOR receiver
E3399_RS21935	COG2205	protein histidine kinase activity
E3399_RS21945	COG2258	MOSC domain
E3399_RS21950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E3399_RS21960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E3399_RS22005	COG1454	alcohol dehydrogenase
E3399_RS22020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E3399_RS22050	COG0437	4 iron, 4 sulfur cluster binding
E3399_RS22055	COG2864	formate dehydrogenase
E3399_RS22070	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
E3399_RS22080	COG0456	acetyltransferase
E3399_RS22095	COG1011	Hydrolase
E3399_RS22100	COG1349	DNA-binding transcription factor activity
E3399_RS22105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS22115	COG3684	Belongs to the aldolase LacD family
E3399_RS22125	COG2017	converts alpha-aldose to the beta-anomer
E3399_RS22130	COG1501	Belongs to the glycosyl hydrolase 31 family
E3399_RS22175	COG0561	phosphatase activity
E3399_RS22230	COG0204	Acyl-transferase
E3399_RS22245	COG3084	Protein conserved in bacteria
E3399_RS22255	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3399_RS22295	COG1739	Uncharacterized protein family UPF0029
E3399_RS22340	COG0805	protein transport
E3399_RS22385	COG0641	radical SAM
E3399_RS22410	COG0561	phosphatase activity
E3399_RS22415	COG2267	carboxylic ester hydrolase activity
E3399_RS22470	COG1011	Hydrolase
E3399_RS22540	COG2959	enzyme of heme biosynthesis
E3399_RS22545	COG3071	HemY protein
E3399_RS22590	COG2244	polysaccharide biosynthetic process
E3399_RS22595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3399_RS22600	COG0456	acetyltransferase
E3399_RS22605	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E3399_RS22610	COG1088	dTDP-glucose 4,6-dehydratase activity
E3399_RS22615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3399_RS22630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3399_RS22650	COG3118	belongs to the thioredoxin family
E3399_RS22670	COG3201	nicotinamide mononucleotide transporter
E3399_RS22720	COG3978	acetolactate synthase activity
E3399_RS22780	COG2186	Transcriptional regulator
E3399_RS22785	COG0477	Major facilitator Superfamily
E3399_RS22790	COG1609	Transcriptional regulator
E3399_RS22795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3399_RS22805	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3399_RS22840	COG1522	sequence-specific DNA binding
E3399_RS22845	COG0716	FMN binding
E3399_RS22860	COG3312	ion transport
E3399_RS22920	COG4533	DNA binding
E3399_RS22925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E3399_RS22930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3399_RS22930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3399_RS22930	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E3399_RS22935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E3399_RS22940	COG0573	inorganic phosphate transmembrane transporter activity
E3399_RS22945	COG0581	inorganic phosphate transmembrane transporter activity
E3399_RS22955	COG0704	Plays a role in the regulation of phosphate uptake
E3399_RS22960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3399_RS22965	COG2252	PERMEase
E3399_RS22970	COG0431	NADPH-dependent FMN reductase
E3399_RS22975	COG2091	lysine biosynthetic process via aminoadipic acid
E3399_RS23095	COG2135	peptidase activity
E3399_RS23150	COG2771	luxR family
E3399_RS23170	COG3328	transposase activity
E3399_RS23235	COG2207	Transcriptional regulator