locus-tag	class	description
E3397_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
E3397_RS00035	COG2271	Major facilitator Superfamily
E3397_RS00040	COG0561	phosphatase activity
E3397_RS00045	COG2186	Transcriptional regulator
E3397_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
E3397_RS00055	COG0800	Aldolase
E3397_RS00065	COG2271	Major facilitator Superfamily
E3397_RS00070	COG2198	Histidine kinase
E3397_RS00070	COG0784	Response regulator, receiver
E3397_RS00070	COG2205	protein histidine kinase activity
E3397_RS00075	COG1879	ABC-type sugar transport system periplasmic component
E3397_RS00080	COG0745	RESPONSE REGULATOR receiver
E3397_RS00085	COG3005	denitrification pathway
E3397_RS00100	COG1858	cytochrome C peroxidase
E3397_RS00110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3397_RS00115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3397_RS00120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3397_RS00130	COG1138	Cytochrome C-type biogenesis protein
E3397_RS00140	COG3088	subunit of a heme lyase
E3397_RS00140	COG4235	cytochrome complex assembly
E3397_RS00145	COG0823	Involved in the tonB-independent uptake of proteins
E3397_RS00150	COG5645	(Lipo)protein
E3397_RS00175	COG2149	membrane
E3397_RS00185	COG0641	radical SAM
E3397_RS00195	COG2610	gluconate transmembrane transporter activity
E3397_RS00200	COG0583	DNA-binding transcription factor activity
E3397_RS00210	COG2814	Major facilitator Superfamily
E3397_RS00235	COG0028	Belongs to the TPP enzyme family
E3397_RS00240	COG0440	acetolactate synthase activity
E3397_RS00245	COG1349	DNA-binding transcription factor activity
E3397_RS00255	COG0738	Major facilitator superfamily
E3397_RS00290	COG2188	Transcriptional regulator
E3397_RS00295	COG3711	transcriptional antiterminator
E3397_RS00295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS00300	COG3414	Phosphotransferase system galactitol-specific IIB component
E3397_RS00305	COG3775	system Galactitol-specific IIC component
E3397_RS00340	COG2723	6-phospho-beta-galactosidase activity
E3397_RS00360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3397_RS00360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS00365	COG3715	PTS system
E3397_RS00370	COG3716	PTS system mannose fructose sorbose family IID component
E3397_RS00385	COG5464	transposase or invertase
E3397_RS00415	COG1335	isochorismatase
E3397_RS00425	COG3710	Transcriptional regulator
E3397_RS00440	COG2771	luxR family
E3397_RS00460	COG2211	Major facilitator Superfamily
E3397_RS00465	COG1501	Belongs to the glycosyl hydrolase 31 family
E3397_RS00470	COG2982	Protein involved in outer membrane biogenesis
E3397_RS00475	COG2233	PERMEase
E3397_RS00480	COG0786	glutamate:sodium symporter activity
E3397_RS00485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E3397_RS00490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3397_RS00495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3397_RS00515	COG2860	membrane
E3397_RS00525	COG0583	DNA-binding transcription factor activity
E3397_RS00530	COG1561	YicC-like family, N-terminal region
E3397_RS00555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3397_RS00585	COG1519	Transferase
E3397_RS00590	COG0859	PFAM glycosyl transferase family 9
E3397_RS00595	COG0438	transferase activity, transferring glycosyl groups
E3397_RS00680	COG1216	Glycosyl transferase, family 2
E3397_RS00685	COG2861	carbohydrate metabolic process
E3397_RS00690	COG4942	peptidase
E3397_RS00700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3397_RS00705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E3397_RS00725	COG2271	Major facilitator Superfamily
E3397_RS00735	COG1609	Transcriptional regulator
E3397_RS00740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E3397_RS00750	COG2186	Transcriptional regulator
E3397_RS00780	COG3722	fumarate hydratase activity
E3397_RS00790	COG2213	PTS system mannitol-specific
E3397_RS00790	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS00805	COG1566	PFAM secretion protein HlyD family protein
E3397_RS00810	COG0625	glutathione transferase activity
E3397_RS00820	COG3276	selenocysteine insertion sequence binding
E3397_RS00825	COG1940	carbohydrate kinase activity
E3397_RS00830	COG1012	belongs to the aldehyde dehydrogenase family
E3397_RS00845	COG0235	Class ii aldolase
E3397_RS00850	COG3623	hexulose-6-phosphate isomerase
E3397_RS00855	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E3397_RS00860	COG1070	Carbohydrate kinase
E3397_RS00865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E3397_RS00870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E3397_RS00875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E3397_RS00885	COG2731	YhcH YjgK YiaL family protein
E3397_RS00895	COG1414	Transcriptional regulator
E3397_RS00900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3397_RS00905	COG3977	Valine--pyruvate aminotransferase
E3397_RS00910	COG0366	Alpha amylase catalytic
E3397_RS00915	COG2992	FlgJ-related protein
E3397_RS00920	COG1609	Transcriptional regulator
E3397_RS00920	COG2207	Transcriptional regulator
E3397_RS00930	COG1070	Carbohydrate kinase
E3397_RS00935	COG4682	membrane
E3397_RS00940	COG3274	enterobacterial common antigen metabolic process
E3397_RS00965	COG2801	Transposase and inactivated derivatives
E3397_RS00990	COG1278	Cold shock
E3397_RS00995	COG2944	sequence-specific DNA binding
E3397_RS01005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E3397_RS01010	COG2885	chlorophyll binding
E3397_RS01015	COG0243	molybdopterin cofactor binding
E3397_RS01020	COG0456	acetyltransferase
E3397_RS01025	COG2818	Glycosylase
E3397_RS01030	COG5571	outer membrane autotransporter
E3397_RS01075	COG1609	Transcriptional regulator
E3397_RS01090	COG0747	negative chemotaxis
E3397_RS01095	COG0601	transmembrane transport
E3397_RS01100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3397_RS01105	COG0444	Belongs to the ABC transporter superfamily
E3397_RS01110	COG4608	Belongs to the ABC transporter superfamily
E3397_RS01115	COG0814	amino acid
E3397_RS01175	COG2199	diguanylate cyclase activity
E3397_RS01175	COG2200	EAL domain
E3397_RS01190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS01195	COG2200	EAL domain
E3397_RS01200	COG2982	Protein involved in outer membrane biogenesis
E3397_RS01205	COG0477	Major facilitator Superfamily
E3397_RS01210	COG1295	ribonuclease BN
E3397_RS01215	COG0583	DNA-binding transcription factor activity
E3397_RS01220	COG2197	response regulator
E3397_RS01240	COG2188	Transcriptional regulator
E3397_RS01245	COG2222	sugar isomerase
E3397_RS01250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS01255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3397_RS01265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3397_RS01270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E3397_RS01275	COG0671	phosphoesterase, PA-phosphatase related
E3397_RS01305	COG0306	phosphate transporter
E3397_RS01310	COG2081	HI0933 family
E3397_RS01315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3397_RS01320	COG1129	ABC transporter
E3397_RS01320	COG0842	Transport permease protein
E3397_RS01325	COG0842	Transport permease protein
E3397_RS01335	COG2091	lysine biosynthetic process via aminoadipic acid
E3397_RS01340	COG0628	permease
E3397_RS01355	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3397_RS01375	COG3714	YhhN family
E3397_RS01385	COG3776	membrane
E3397_RS01390	COG0742	ribosomal rna small subunit methyltransferase
E3397_RS01395	COG0552	protein localization to endoplasmic reticulum
E3397_RS01400	COG2884	Cell division ATP-binding protein ftsE
E3397_RS01405	COG2177	Part of the ABC transporter FtsEX involved in
E3397_RS01480	COG0584	glycerophosphoryl diester phosphodiesterase
E3397_RS01490	COG0405	Gamma-glutamyltransferase
E3397_RS01495	COG1735	metal-dependent hydrolase with the TIM-barrel fold
E3397_RS01510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS01515	COG1247	-acetyltransferase
E3397_RS01520	COG0673	inositol 2-dehydrogenase activity
E3397_RS01525	COG1741	Belongs to the pirin family
E3397_RS01530	COG1609	Transcriptional regulator
E3397_RS01535	COG3265	gluconokinase activity
E3397_RS01540	COG2610	gluconate transmembrane transporter activity
E3397_RS01575	COG0058	SHG alpha-glucan phosphorylase activity
E3397_RS01580	COG1414	Transcriptional regulator
E3397_RS01585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E3397_RS01590	COG0129	dihydroxy-acid dehydratase activity
E3397_RS01600	COG0371	Dehydrogenase
E3397_RS01615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E3397_RS01630	COG1349	DNA-binding transcription factor activity
E3397_RS01635	COG4650	regulator
E3397_RS01645	COG1690	Belongs to the RtcB family
E3397_RS01655	COG3077	Addiction module antitoxin, RelB DinJ family
E3397_RS01660	COG3041	Addiction module toxin RelE StbE family
E3397_RS01670	COG0058	SHG alpha-glucan phosphorylase activity
E3397_RS01675	COG1640	4-alpha-glucanotransferase
E3397_RS01680	COG2610	gluconate transmembrane transporter activity
E3397_RS01690	COG1040	competence protein
E3397_RS01700	COG5464	transposase or invertase
E3397_RS01715	COG1918	ferrous iron import across plasma membrane
E3397_RS01720	COG2183	response to ionizing radiation
E3397_RS01725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3397_RS01745	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E3397_RS01755	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3397_RS01760	COG1011	Hydrolase
E3397_RS01770	COG0494	nUDIX hydrolase
E3397_RS01775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E3397_RS01780	COG4972	Pilus assembly protein
E3397_RS01785	COG3166	PFAM Fimbrial assembly family protein
E3397_RS01800	COG4796	Type ii and iii secretion system protein
E3397_RS01815	COG3266	domain, Protein
E3397_RS01820	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E3397_RS01825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3397_RS01865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3397_RS01900	COG1289	transmembrane transporter activity
E3397_RS01910	COG1765	OsmC-like protein
E3397_RS01915	COG3954	Phosphoribulokinase
E3397_RS01925	COG0429	hydrolase of the alpha beta-hydrolase fold
E3397_RS01940	COG0488	(ABC) transporter
E3397_RS01955	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E3397_RS01960	COG1047	Peptidyl-prolyl cis-trans
E3397_RS01970	COG0545	Peptidyl-prolyl cis-trans isomerase
E3397_RS01975	COG2964	Protein conserved in bacteria
E3397_RS02030	COG0051	transcription antitermination factor activity, RNA binding
E3397_RS02055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E3397_RS02135	COG0201	protein transport
E3397_RS02175	COG0789	Transcriptional regulator
E3397_RS02180	COG3036	rescue of stalled ribosome
E3397_RS02210	COG0758	DNA mediated transformation
E3397_RS02220	COG0551	DNA topoisomerase type I activity
E3397_RS02240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E3397_RS02280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3397_RS02285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3397_RS02290	COG1309	transcriptional regulator
E3397_RS02305	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E3397_RS02330	COG4145	pantothenate transmembrane transporter activity
E3397_RS02335	COG3924	membrane
E3397_RS02340	COG0439	Biotin carboxylase
E3397_RS02345	COG0511	ligase activity, forming carbon-carbon bonds
E3397_RS02360	COG0604	alcohol dehydrogenase
E3397_RS02365	COG2199	diguanylate cyclase activity
E3397_RS02365	COG2200	EAL domain
E3397_RS02370	COG1077	Cell shape determining protein MreB Mrl
E3397_RS02375	COG1792	Involved in formation and maintenance of cell shape
E3397_RS02380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E3397_RS02395	COG3164	Protein of unknown function
E3397_RS02400	COG0312	modulator of DNA gyrase
E3397_RS02405	COG0583	DNA-binding transcription factor activity
E3397_RS02425	COG2732	(Barnase) inhibitor
E3397_RS02450	COG2188	Transcriptional regulator
E3397_RS02460	COG0471	metal ion transport
E3397_RS02465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3397_RS02470	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3397_RS02475	COG3630	sodium ion export across plasma membrane
E3397_RS02480	COG5016	pyruvate
E3397_RS02480	COG0511	ligase activity, forming carbon-carbon bonds
E3397_RS02500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3397_RS02505	COG3105	Protein conserved in bacteria
E3397_RS02510	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E3397_RS02535	COG0625	glutathione transferase activity
E3397_RS02540	COG2969	positive regulation of protein catabolic process
E3397_RS02570	COG2731	YhcH YjgK YiaL family protein
E3397_RS02575	COG0402	S-adenosylhomocysteine deaminase activity
E3397_RS02580	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E3397_RS02585	COG4804	nuclease activity
E3397_RS02590	COG0493	'glutamate synthase
E3397_RS02595	COG0069	glutamate synthase activity
E3397_RS02595	COG0070	glutamate synthase
E3397_RS02595	COG0067	glutamate synthase
E3397_RS02600	COG1242	4 iron, 4 sulfur cluster binding
E3397_RS02605	COG5002	protein histidine kinase activity
E3397_RS02605	COG0784	Response regulator, receiver
E3397_RS02605	COG2198	Histidine kinase
E3397_RS02610	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E3397_RS02620	COG0515	serine threonine protein kinase
E3397_RS02625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS02650	COG1137	ATPase activity
E3397_RS02655	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E3397_RS02660	COG3117	lipopolysaccharide transmembrane transporter activity
E3397_RS02665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E3397_RS02675	COG0530	calcium, potassium:sodium antiporter activity
E3397_RS02680	COG1127	ABC transporter
E3397_RS02685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3397_RS02690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3397_RS02695	COG2854	intermembrane phospholipid transfer
E3397_RS02700	COG3113	response to antibiotic
E3397_RS02705	COG5007	Belongs to the BolA IbaG family
E3397_RS02715	COG3423	Transcriptional regulator
E3397_RS02720	COG0142	geranyltranstransferase activity
E3397_RS02735	COG0697	spore germination
E3397_RS02745	COG2027	D-alanyl-D-alanine carboxypeptidase
E3397_RS02755	COG1534	Rna-binding protein
E3397_RS02770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E3397_RS02780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3397_RS02850	COG0513	Belongs to the DEAD box helicase family
E3397_RS02855	COG0814	amino acid
E3397_RS02865	COG3034	peptidoglycan biosynthetic process
E3397_RS02870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3397_RS02875	COG0826	peptidase U32
E3397_RS02880	COG0826	peptidase U32
E3397_RS02885	COG3154	lipid carrier protein
E3397_RS02890	COG3153	acetyltransferase
E3397_RS02905	COG0693	protein deglycase activity
E3397_RS02910	COG0702	epimerase
E3397_RS02915	COG2823	Periplasmic or secreted lipoprotein
E3397_RS02935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3397_RS02945	COG1063	alcohol dehydrogenase
E3397_RS02950	COG3775	system Galactitol-specific IIC component
E3397_RS02955	COG3414	Phosphotransferase system galactitol-specific IIB component
E3397_RS02960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS02975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3397_RS02975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3397_RS02975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS02980	COG1105	Belongs to the carbohydrate kinase PfkB family
E3397_RS02990	COG1349	DNA-binding transcription factor activity
E3397_RS02995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS03000	COG2721	sulfolactate sulfo-lyase activity
E3397_RS03010	COG2084	Dehydrogenase
E3397_RS03015	COG1929	Belongs to the glycerate kinase type-1 family
E3397_RS03025	COG0583	DNA-binding transcription factor activity
E3397_RS03045	COG1882	Formate acetyltransferase
E3397_RS03050	COG1760	l-serine dehydratase
E3397_RS03055	COG0814	amino acid
E3397_RS03070	COG1741	Belongs to the pirin family
E3397_RS03075	COG0583	DNA-binding transcription factor activity
E3397_RS03080	COG3152	Membrane
E3397_RS03085	COG0435	Glutathione S-transferase
E3397_RS03090	COG2259	Doxx family
E3397_RS03100	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E3397_RS03105	COG4575	ribosome binding
E3397_RS03110	COG1422	Protein of unknown function (DUF1090)
E3397_RS03120	COG0586	Pfam SNARE associated Golgi protein
E3397_RS03135	COG0673	inositol 2-dehydrogenase activity
E3397_RS03140	COG2949	membrane
E3397_RS03145	COG1451	nucleotide metabolic process
E3397_RS03155	COG0446	pyridine nucleotide-disulphide oxidoreductase
E3397_RS03155	COG1902	pentaerythritol trinitrate reductase activity
E3397_RS03165	COG0840	transmembrane signaling receptor activity
E3397_RS03165	COG0840	transmembrane signaling receptor activity
E3397_RS03170	COG0840	transmembrane signaling receptor activity
E3397_RS03175	COG1695	Transcriptional regulator
E3397_RS03180	COG2375	cellular response to nickel ion
E3397_RS03205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E3397_RS03230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E3397_RS03245	COG4991	sh3 domain protein
E3397_RS03250	COG3025	triphosphatase activity
E3397_RS03270	COG2268	Band 7 protein
E3397_RS03275	COG1585	Membrane protein implicated in regulation of membrane protease activity
E3397_RS03315	COG3384	dioxygenase
E3397_RS03320	COG0754	glutathionylspermidine amidase activity
E3397_RS03335	COG0494	nUDIX hydrolase
E3397_RS03340	COG3151	Protein conserved in bacteria
E3397_RS03345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E3397_RS03350	COG3150	esterase
E3397_RS03360	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E3397_RS03365	COG2249	NAD(P)H dehydrogenase (quinone) activity
E3397_RS03380	COG3111	PFAM Bacterial OB fold (BOF) protein
E3397_RS03385	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E3397_RS03435	COG0471	metal ion transport
E3397_RS03445	COG1979	alcohol dehydrogenase
E3397_RS03450	COG2207	Transcriptional regulator
E3397_RS03470	COG0848	biopolymer transport protein
E3397_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
E3397_RS03500	COG0840	transmembrane signaling receptor activity
E3397_RS03510	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3397_RS03515	COG0437	4 iron, 4 sulfur cluster binding
E3397_RS03520	COG5557	Pfam Polysulphide reductase, NrfD
E3397_RS03525	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E3397_RS03530	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3397_RS03535	COG1773	rubredoxin
E3397_RS03545	COG0298	carbon dioxide binding
E3397_RS03550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3397_RS03560	COG0625	glutathione transferase activity
E3397_RS03565	COG0754	glutathionylspermidine amidase activity
E3397_RS03580	COG0246	Mannitol dehydrogenase
E3397_RS03590	COG2271	Major facilitator Superfamily
E3397_RS03615	COG1012	belongs to the aldehyde dehydrogenase family
E3397_RS03620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E3397_RS03630	COG0531	amino acid
E3397_RS03660	COG2301	Belongs to the HpcH HpaI aldolase family
E3397_RS03665	COG2030	dehydratase
E3397_RS03670	COG0427	acetyl-CoA hydrolase
E3397_RS03685	COG1811	Na channel or pump
E3397_RS03690	COG1982	Orn Lys Arg decarboxylase major
E3397_RS03695	COG2211	Major facilitator Superfamily
E3397_RS03720	COG3171	Protein conserved in bacteria
E3397_RS03730	COG0252	asparaginase activity
E3397_RS03740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3397_RS03755	COG0762	integral membrane protein
E3397_RS03760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3397_RS03765	COG2805	Type II/IV secretion system protein
E3397_RS03790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3397_RS03795	COG2356	endonuclease I
E3397_RS03805	COG2814	Major facilitator Superfamily
E3397_RS03825	COG1166	arginine decarboxylase activity
E3397_RS03835	COG2186	Transcriptional regulator
E3397_RS03845	COG0246	Mannitol dehydrogenase
E3397_RS03850	COG1063	alcohol dehydrogenase
E3397_RS03855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E3397_RS03860	COG2731	YhcH YjgK YiaL family protein
E3397_RS03865	COG2267	carboxylic ester hydrolase activity
E3397_RS03875	COG0501	Belongs to the peptidase M48B family
E3397_RS03880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E3397_RS03885	COG1122	ATPase activity
E3397_RS03890	COG1122	ATPase activity
E3397_RS03920	COG0191	fructose-bisphosphate aldolase activity
E3397_RS03925	COG0668	transmembrane transport
E3397_RS03935	COG2968	Membrane
E3397_RS03950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3397_RS03955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3397_RS03975	COG0006	proline dipeptidase activity
E3397_RS03980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3397_RS03985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3397_RS04015	COG2723	6-phospho-beta-galactosidase activity
E3397_RS04025	COG1272	protein, Hemolysin III
E3397_RS04085	COG4942	peptidase
E3397_RS04095	COG0582	viral genome integration into host DNA
E3397_RS04125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E3397_RS04160	COG0431	NADPH-dependent FMN reductase
E3397_RS04195	COG3121	Chaperone
E3397_RS04200	COG3188	usher protein
E3397_RS04210	COG1285	pathogenesis
E3397_RS04255	COG0406	alpha-ribazole phosphatase activity
E3397_RS04260	COG2015	COG2015, Alkyl sulfatase and related hydrolases
E3397_RS04265	COG3264	Mechanosensitive ion channel
E3397_RS04265	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
E3397_RS04270	COG2067	long-chain fatty acid transport protein
E3397_RS04275	COG3596	GTP binding
E3397_RS04280	COG2378	regulation of single-species biofilm formation
E3397_RS04290	COG2378	regulation of single-species biofilm formation
E3397_RS04315	COG2003	Belongs to the UPF0758 family
E3397_RS04365	COG3188	usher protein
E3397_RS04400	COG0814	amino acid
E3397_RS04415	COG0183	Belongs to the thiolase family
E3397_RS04425	COG1028	Short-chain dehydrogenase reductase Sdr
E3397_RS04430	COG2814	Major facilitator Superfamily
E3397_RS04435	COG1794	racemase activity, acting on amino acids and derivatives
E3397_RS04440	COG0583	DNA-binding transcription factor activity
E3397_RS04450	COG1609	Transcriptional regulator
E3397_RS04470	COG0667	Aldo Keto reductase
E3397_RS04480	COG0861	Integral membrane protein TerC family
E3397_RS04515	COG2165	general secretion pathway protein
E3397_RS04520	COG4795	General secretion pathway protein
E3397_RS04530	COG4967	type IV pilus modification protein PilV
E3397_RS04535	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E3397_RS04545	COG1074	ATP-dependent DNA helicase activity
E3397_RS04550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3397_RS04560	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3397_RS04575	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E3397_RS04580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3397_RS04585	COG2962	Rard protein
E3397_RS04590	COG2166	iron-sulfur cluster assembly
E3397_RS04595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3397_RS04605	COG0583	DNA-binding transcription factor activity
E3397_RS04610	COG2363	Small membrane protein
E3397_RS04620	COG1349	DNA-binding transcription factor activity
E3397_RS04640	COG0738	Major facilitator superfamily
E3397_RS04645	COG0235	Class ii aldolase
E3397_RS04650	COG1454	alcohol dehydrogenase
E3397_RS04660	COG1760	l-serine dehydratase
E3397_RS04665	COG0814	amino acid
E3397_RS04670	COG1611	Belongs to the LOG family
E3397_RS04690	COG3098	single-species biofilm formation
E3397_RS04700	COG0716	FMN binding
E3397_RS04710	COG2271	Major facilitator Superfamily
E3397_RS04715	COG4948	Mandelate Racemase Muconate Lactonizing
E3397_RS04720	COG4948	Mandelate Racemase Muconate Lactonizing
E3397_RS04725	COG1929	Belongs to the glycerate kinase type-1 family
E3397_RS04730	COG4999	Histidine kinase
E3397_RS04730	COG2205	protein histidine kinase activity
E3397_RS04730	COG3437	response regulator, receiver
E3397_RS04730	COG3850	Histidine kinase
E3397_RS04740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3397_RS04745	COG3609	addiction module antidote protein, CC2985 family
E3397_RS04775	COG3539	Fimbrial protein
E3397_RS04780	COG3121	Chaperone
E3397_RS04785	COG3188	usher protein
E3397_RS04790	COG3539	Fimbrial protein
E3397_RS04795	COG3956	TIGRFAM MazG family protein
E3397_RS04810	COG0602	queuosine metabolic process
E3397_RS04815	COG0321	lipoyl(octanoyl) transferase activity
E3397_RS04815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3397_RS04820	COG0720	synthase
E3397_RS04845	COG1203	CRISPR-associated helicase, Cas3
E3397_RS04860	COG1857	crispr-associated protein
E3397_RS04875	COG1518	maintenance of DNA repeat elements
E3397_RS04880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3397_RS04885	COG2234	aminopeptidase activity
E3397_RS04940	COG1388	LysM domain
E3397_RS04940	COG4942	peptidase
E3397_RS04955	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E3397_RS04960	COG0163	prenyltransferase activity
E3397_RS04970	COG1349	DNA-binding transcription factor activity
E3397_RS04975	COG2084	Dehydrogenase
E3397_RS04985	COG0235	Class ii aldolase
E3397_RS04990	COG3622	Belongs to the hyi family
E3397_RS04995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3397_RS05000	COG2610	gluconate transmembrane transporter activity
E3397_RS05010	COG0477	Major facilitator Superfamily
E3397_RS05090	COG2207	Transcriptional regulator
E3397_RS05180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E3397_RS05200	COG0741	lytic transglycosylase activity
E3397_RS05265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3397_RS05270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3397_RS05275	COG1121	(ABC) transporter
E3397_RS05295	COG0309	Hydrogenase expression formation protein (HypE)
E3397_RS05300	COG0409	Hydrogenase expression formation protein
E3397_RS05305	COG0298	carbon dioxide binding
E3397_RS05310	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E3397_RS05325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3397_RS05330	COG0651	ATP synthesis coupled electron transport
E3397_RS05335	COG0650	Formate hydrogenlyase subunit 4
E3397_RS05340	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E3397_RS05340	COG3261	NADH dehydrogenase
E3397_RS05345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3397_RS05350	COG3260	NADH ubiquinone oxidoreductase 20
E3397_RS05360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3397_RS05370	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3397_RS05375	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E3397_RS05400	COG1349	DNA-binding transcription factor activity
E3397_RS05405	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
E3397_RS05420	COG3732	PTS system glucitol sorbitol-specific
E3397_RS05425	COG3730	PTS system glucitol sorbitol-specific
E3397_RS05430	COG2951	lytic endotransglycosylase activity
E3397_RS05440	COG1546	Belongs to the CinA family
E3397_RS05465	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E3397_RS05495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3397_RS05500	COG1238	metal cluster binding
E3397_RS05520	COG2814	Major facilitator Superfamily
E3397_RS05525	COG1566	PFAM secretion protein HlyD family protein
E3397_RS05530	COG1846	Transcriptional regulator
E3397_RS05535	COG2814	Major facilitator Superfamily
E3397_RS05580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3397_RS05590	COG4575	ribosome binding
E3397_RS05620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3397_RS05625	COG0640	Transcriptional regulator
E3397_RS05630	COG0401	homolog of Blt101
E3397_RS05640	COG1652	LysM domain
E3397_RS05645	COG1802	Transcriptional regulator
E3397_RS05650	COG1113	amino acid transport
E3397_RS05655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E3397_RS05660	COG1012	belongs to the aldehyde dehydrogenase family
E3397_RS05665	COG0579	oxidoreductase
E3397_RS05700	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3397_RS05715	COG2990	Protein conserved in bacteria
E3397_RS05735	COG2819	hydrolase of the alpha beta superfamily
E3397_RS05745	COG1132	(ABC) transporter
E3397_RS05810	COG0582	viral genome integration into host DNA
E3397_RS05820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3397_RS05845	COG2867	negative regulation of translational initiation
E3397_RS05860	COG0497	DNA recombination
E3397_RS05880	COG4536	flavin adenine dinucleotide binding
E3397_RS05885	COG4137	Cytochrome C assembly protein
E3397_RS05890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3397_RS05915	COG2199	diguanylate cyclase activity
E3397_RS05930	COG0287	Prephenate dehydrogenase
E3397_RS05930	COG1605	Chorismate mutase
E3397_RS05940	COG1605	Chorismate mutase
E3397_RS05940	COG0077	Prephenate dehydratase
E3397_RS05950	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E3397_RS05960	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3397_RS05975	COG0542	response to heat
E3397_RS06005	COG0477	Major facilitator Superfamily
E3397_RS06010	COG5544	Lipoprotein
E3397_RS06015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3397_RS06025	COG3148	PFAM DTW domain containing protein
E3397_RS06030	COG3118	belongs to the thioredoxin family
E3397_RS06035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3397_RS06055	COG0583	DNA-binding transcription factor activity
E3397_RS06060	COG0513	Belongs to the DEAD box helicase family
E3397_RS06070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E3397_RS06100	COG3086	response to oxidative stress
E3397_RS06140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3397_RS06145	COG0583	DNA-binding transcription factor activity
E3397_RS06150	COG2223	nitrite transmembrane transporter activity
E3397_RS06155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3397_RS06160	COG1737	Transcriptional regulator
E3397_RS06170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3397_RS06170	COG1263	PTS System
E3397_RS06175	COG0560	Phosphoserine phosphatase
E3397_RS06200	COG2205	protein histidine kinase activity
E3397_RS06205	COG3170	Tfp pilus assembly protein FimV
E3397_RS06210	COG2204	response regulator
E3397_RS06215	COG0347	Belongs to the P(II) protein family
E3397_RS06220	COG3104	oligopeptide transport
E3397_RS06230	COG0531	amino acid
E3397_RS06235	COG3710	Transcriptional regulator
E3397_RS06250	COG2814	Major facilitator Superfamily
E3397_RS06255	COG3711	transcriptional antiterminator
E3397_RS06265	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E3397_RS06310	COG0822	iron-sulfur transferase activity
E3397_RS06330	COG0633	Ferredoxin
E3397_RS06335	COG2975	iron-sulfur cluster assembly
E3397_RS06360	COG2897	thiosulfate sulfurtransferase activity
E3397_RS06365	COG2373	Large extracellular alpha-helical protein
E3397_RS06370	COG4953	penicillin-binding protein 1C
E3397_RS06375	COG0243	molybdopterin cofactor binding
E3397_RS06380	COG0437	4 iron, 4 sulfur cluster binding
E3397_RS06420	COG2976	Protein conserved in bacteria
E3397_RS06435	COG1645	bacterial-type flagellum-dependent swarming motility
E3397_RS06475	COG0516	GMP reductase activity
E3397_RS06475	COG0517	IMP dehydrogenase activity
E3397_RS06510	COG2200	EAL domain
E3397_RS06525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E3397_RS06540	COG2233	PERMEase
E3397_RS06550	COG1393	Belongs to the ArsC family
E3397_RS06560	COG0628	permease
E3397_RS06565	COG3835	regulator
E3397_RS06570	COG2610	gluconate transmembrane transporter activity
E3397_RS06575	COG1929	Belongs to the glycerate kinase type-1 family
E3397_RS06580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3397_RS06585	COG2716	regulation of RNA biosynthetic process
E3397_RS06590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E3397_RS06595	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E3397_RS06605	COG2321	neutral zinc metallopeptidase
E3397_RS06625	COG1393	Belongs to the ArsC family
E3397_RS06635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3397_RS06640	COG3850	Histidine kinase
E3397_RS06645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3397_RS06645	COG0493	'glutamate synthase
E3397_RS06660	COG5342	invasion associated locus B
E3397_RS06670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E3397_RS06805	COG2837	iron assimilation
E3397_RS06825	COG4208	sulfate ABC transporter
E3397_RS06880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS06905	COG3530	Putative quorum-sensing-regulated virulence factor
E3397_RS06910	COG0385	Bile acid
E3397_RS06915	COG0583	DNA-binding transcription factor activity
E3397_RS06925	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E3397_RS06930	COG2211	Major facilitator Superfamily
E3397_RS06940	COG0583	DNA-binding transcription factor activity
E3397_RS06965	COG3415	Transposase
E3397_RS06970	COG3415	Transposase
E3397_RS06985	COG2199	diguanylate cyclase activity
E3397_RS06985	COG2200	EAL domain
E3397_RS06990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3397_RS07005	COG0667	Aldo Keto reductase
E3397_RS07010	COG3961	Belongs to the TPP enzyme family
E3397_RS07025	COG0436	Aminotransferase
E3397_RS07035	COG1560	Kdo2-lipid A biosynthetic process
E3397_RS07075	COG2116	formate transmembrane transporter activity
E3397_RS07090	COG3691	Protein conserved in bacteria
E3397_RS07105	COG2062	phosphohistidine phosphatase, SixA
E3397_RS07130	COG0730	response to heat
E3397_RS07135	COG3101	peptidyl-lysine hydroxylation
E3397_RS07150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3397_RS07170	COG3423	Transcriptional regulator
E3397_RS07195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3397_RS07205	COG0586	Pfam SNARE associated Golgi protein
E3397_RS07215	COG0285	dihydrofolate synthase activity
E3397_RS07220	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E3397_RS07225	COG1286	toxin biosynthetic process
E3397_RS07230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E3397_RS07235	COG3829	transcription factor binding
E3397_RS07245	COG0531	amino acid
E3397_RS07250	COG3457	Alanine racemase
E3397_RS07255	COG0833	amino acid
E3397_RS07290	COG1090	epimerase
E3397_RS07295	COG0625	glutathione transferase activity
E3397_RS07300	COG0625	glutathione transferase activity
E3397_RS07305	COG0622	Phosphoesterase
E3397_RS07315	COG1609	Transcriptional regulator
E3397_RS07320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS07330	COG3037	sugar-specific permease SgaT UlaA
E3397_RS07335	COG3959	Transketolase, thiamine diphosphate binding domain
E3397_RS07340	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E3397_RS07345	COG1288	antiporter activity
E3397_RS07370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3397_RS07375	COG0490	domain, Protein
E3397_RS07375	COG0471	metal ion transport
E3397_RS07390	COG0436	Aminotransferase
E3397_RS07395	COG0583	DNA-binding transcription factor activity
E3397_RS07445	COG0839	Belongs to the complex I subunit 6 family
E3397_RS07455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3397_RS07460	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3397_RS07470	COG0784	Response regulator, receiver
E3397_RS07470	COG0835	chemotaxis
E3397_RS07480	COG2153	protein acetylation
E3397_RS07485	COG4575	ribosome binding
E3397_RS07490	COG1169	isochorismate synthase
E3397_RS07580	COG1414	Transcriptional regulator
E3397_RS07590	COG2271	Major facilitator Superfamily
E3397_RS07610	COG0247	lactate metabolic process
E3397_RS07620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E3397_RS07625	COG2271	Major facilitator Superfamily
E3397_RS07630	COG0584	glycerophosphoryl diester phosphodiesterase
E3397_RS07635	COG0583	DNA-binding transcription factor activity
E3397_RS07640	COG2814	Major facilitator Superfamily
E3397_RS07645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3397_RS07675	COG4948	Mandelate Racemase Muconate Lactonizing
E3397_RS07695	COG2198	Histidine kinase
E3397_RS07695	COG0642	Histidine kinase
E3397_RS07720	COG4615	Cyclic peptide transporter
E3397_RS07730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3397_RS07730	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3397_RS07735	COG3062	negative regulation of establishment of protein localization
E3397_RS07745	COG0437	4 iron, 4 sulfur cluster binding
E3397_RS07750	COG0348	domain, Protein
E3397_RS07755	COG3043	anaerobic respiration
E3397_RS07760	COG3005	denitrification pathway
E3397_RS07770	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3397_RS07775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3397_RS07780	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3397_RS07790	COG1138	Cytochrome C-type biogenesis protein
E3397_RS07800	COG4235	cytochrome complex assembly
E3397_RS07800	COG3088	subunit of a heme lyase
E3397_RS07805	COG2197	response regulator
E3397_RS07820	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3397_RS07870	COG1061	Type III restriction enzyme res subunit
E3397_RS07880	COG2814	Major facilitator Superfamily
E3397_RS07890	COG4172	Belongs to the ABC transporter superfamily
E3397_RS07895	COG4239	(ABC) transporter, permease
E3397_RS07900	COG4174	ABC transporter (Permease)
E3397_RS07905	COG4166	transmembrane transport
E3397_RS07910	COG2200	EAL domain
E3397_RS07915	COG0791	NLP P60 protein
E3397_RS07920	COG0671	phosphoesterase, PA-phosphatase related
E3397_RS07925	COG0523	cobalamin synthesis protein
E3397_RS07960	COG1105	Belongs to the carbohydrate kinase PfkB family
E3397_RS07965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3397_RS07965	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E3397_RS07965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3397_RS07975	COG2855	membrane
E3397_RS07980	COG0583	DNA-binding transcription factor activity
E3397_RS07985	COG0833	amino acid
E3397_RS07990	COG4771	TonB-dependent receptor
E3397_RS07995	COG2271	Major facilitator Superfamily
E3397_RS08000	COG0560	Phosphoserine phosphatase
E3397_RS08005	COG1760	l-serine dehydratase
E3397_RS08025	COG2311	Membrane
E3397_RS08055	COG0493	'glutamate synthase
E3397_RS08065	COG2949	membrane
E3397_RS08075	COG1346	cytolysis
E3397_RS08090	COG2271	Major facilitator Superfamily
E3397_RS08105	COG0625	glutathione transferase activity
E3397_RS08110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3397_RS08125	COG1538	Outer membrane efflux protein
E3397_RS08130	COG1028	Short-chain dehydrogenase reductase Sdr
E3397_RS08135	COG0586	Pfam SNARE associated Golgi protein
E3397_RS08145	COG1686	Belongs to the peptidase S11 family
E3397_RS08150	COG0277	FAD linked oxidase domain protein
E3397_RS08160	COG1732	Glycine betaine
E3397_RS08165	COG1174	glycine betaine transport
E3397_RS08170	COG1125	glycine betaine transport
E3397_RS08175	COG1174	glycine betaine transport
E3397_RS08190	COG3275	phosphorelay sensor kinase activity
E3397_RS08200	COG4807	Protein conserved in bacteria
E3397_RS08210	COG4808	Protein conserved in bacteria
E3397_RS08235	COG3121	Chaperone
E3397_RS08240	COG3188	usher protein
E3397_RS08245	COG3539	Fimbrial protein
E3397_RS08250	COG5455	response to cobalt ion
E3397_RS08265	COG2188	Transcriptional regulator
E3397_RS08270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS08275	COG1397	ADP-ribosylglycohydrolase
E3397_RS08280	COG2211	Major facilitator Superfamily
E3397_RS08285	COG1830	Aldolase
E3397_RS08310	COG0826	peptidase U32
E3397_RS08330	COG0745	RESPONSE REGULATOR receiver
E3397_RS08335	COG2205	protein histidine kinase activity
E3397_RS08365	COG0443	Heat shock 70 kDa protein
E3397_RS08370	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E3397_RS08375	COG5001	Diguanylate cyclase
E3397_RS08375	COG3447	MASE1 domain protein
E3397_RS08375	COG5002	protein histidine kinase activity
E3397_RS08390	COG2982	Protein involved in outer membrane biogenesis
E3397_RS08395	COG1253	flavin adenine dinucleotide binding
E3397_RS08415	COG0463	Glycosyl transferase, family 2
E3397_RS08420	COG1045	serine acetyltransferase
E3397_RS08425	COG0438	transferase activity, transferring glycosyl groups
E3397_RS08435	COG1216	Glycosyl transferase, family 2
E3397_RS08440	COG0110	maltose O-acetyltransferase activity
E3397_RS08445	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E3397_RS08450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3397_RS08460	COG0297	glycogen (starch) synthase activity
E3397_RS08475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3397_RS08480	COG2244	polysaccharide biosynthetic process
E3397_RS08485	COG2327	Polysaccharide pyruvyl transferase
E3397_RS08515	COG0438	transferase activity, transferring glycosyl groups
E3397_RS08600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3397_RS08605	COG0583	DNA-binding transcription factor activity
E3397_RS08615	COG0531	amino acid
E3397_RS08620	COG2925	Exonuclease
E3397_RS08660	COG1289	transmembrane transporter activity
E3397_RS08695	COG4656	Part of a membrane complex involved in electron transport
E3397_RS08700	COG1454	alcohol dehydrogenase
E3397_RS08700	COG1012	belongs to the aldehyde dehydrogenase family
E3397_RS08715	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
E3397_RS08730	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E3397_RS08860	COG1122	ATPase activity
E3397_RS08895	COG0534	Mate efflux family protein
E3397_RS08945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E3397_RS08990	COG0582	viral genome integration into host DNA
E3397_RS09040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3397_RS09050	COG1418	mRNA catabolic process
E3397_RS09055	COG0270	DNA (cytosine-5-)-methyltransferase activity
E3397_RS09060	COG3727	T/G mismatch-specific endonuclease activity
E3397_RS09065	COG0697	spore germination
E3397_RS09070	COG2354	Protein conserved in bacteria
E3397_RS09075	COG5475	Uncharacterized small protein (DUF2158)
E3397_RS09180	COG0425	Belongs to the sulfur carrier protein TusA family
E3397_RS09235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3397_RS09245	COG0765	amino acid transport
E3397_RS09250	COG1126	abc transporter atp-binding protein
E3397_RS09255	COG2197	response regulator
E3397_RS09270	COG2197	response regulator
E3397_RS09315	COG3318	Belongs to the UPF0149 family
E3397_RS09315	COG3012	SEC-C Motif Domain Protein
E3397_RS09320	COG0814	amino acid
E3397_RS09330	COG1528	Iron-storage protein
E3397_RS09345	COG1528	Iron-storage protein
E3397_RS09450	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E3397_RS09465	COG3102	Protein conserved in bacteria
E3397_RS09485	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E3397_RS09490	COG1801	Protein of unknown function DUF72
E3397_RS09495	COG1335	isochorismatase
E3397_RS09505	COG0494	nUDIX hydrolase
E3397_RS09545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3397_RS09555	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E3397_RS09560	COG0739	heme binding
E3397_RS09565	COG1560	Kdo2-lipid A biosynthetic process
E3397_RS09575	COG1737	Transcriptional regulator
E3397_RS09580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3397_RS09585	COG0129	dihydroxy-acid dehydratase activity
E3397_RS09590	COG0800	Aldolase
E3397_RS09600	COG3141	response to X-ray
E3397_RS09610	COG2979	Protein of unknown function (DUF533)
E3397_RS09615	COG1770	oligopeptidase
E3397_RS09620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3397_RS09625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3397_RS09635	COG2372	response to copper ion
E3397_RS09640	COG1276	copper resistance
E3397_RS09660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3397_RS09760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E3397_RS09780	COG5562	phage envelope protein
E3397_RS09815	COG3008	intermembrane lipid transfer
E3397_RS09820	COG2995	paraquat-inducible protein a
E3397_RS09825	COG1956	GAF domain-containing protein
E3397_RS09845	COG2814	Major facilitator Superfamily
E3397_RS09850	COG1414	Transcriptional regulator
E3397_RS09880	COG0768	penicillin binding
E3397_RS09885	COG2226	methyltransferase
E3397_RS09900	COG3716	PTS system mannose fructose sorbose family IID component
E3397_RS09905	COG3715	PTS system
E3397_RS09910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS09910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3397_RS09915	COG1253	flavin adenine dinucleotide binding
E3397_RS09920	COG2200	EAL domain
E3397_RS09925	COG1760	l-serine dehydratase
E3397_RS09945	COG0251	oxidation-reduction process
E3397_RS09950	COG1199	ATP-dependent helicase activity
E3397_RS09960	COG3065	identical protein binding
E3397_RS09970	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E3397_RS09980	COG2894	cell division
E3397_RS09995	COG0179	Fumarylacetoacetate (FAA) hydrolase
E3397_RS10035	COG2719	SpoVR family
E3397_RS10055	COG1619	proteins homologs of microcin C7 resistance protein MccF
E3397_RS10080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E3397_RS10090	COG1294	oxidase, subunit
E3397_RS10095	COG1271	oxidase subunit
E3397_RS10100	COG1773	rubredoxin
E3397_RS10105	COG1999	signal sequence binding
E3397_RS10110	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E3397_RS10115	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E3397_RS10125	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3397_RS10140	COG0012	GTP binding
E3397_RS10155	COG0659	secondary active sulfate transmembrane transporter activity
E3397_RS10205	COG0387	Pfam Sodium calcium exchanger
E3397_RS10210	COG4572	Cation transport regulator
E3397_RS10215	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E3397_RS10220	COG4932	domain protein
E3397_RS10225	COG2197	response regulator
E3397_RS10230	COG3850	Histidine kinase
E3397_RS10235	COG2223	nitrite transmembrane transporter activity
E3397_RS10240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3397_RS10245	COG1140	nitrate reductase beta subunit
E3397_RS10250	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E3397_RS10255	COG2181	nitrate reductase activity
E3397_RS10300	COG0788	formyltetrahydrofolate deformylase activity
E3397_RS10310	COG1752	Esterase of the alpha-beta hydrolase superfamily
E3397_RS10315	COG0745	RESPONSE REGULATOR receiver
E3397_RS10320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E3397_RS10335	COG1012	belongs to the aldehyde dehydrogenase family
E3397_RS10335	COG1454	alcohol dehydrogenase
E3397_RS10340	COG2095	MarC family integral membrane protein
E3397_RS10370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3397_RS10390	COG2350	Protein conserved in bacteria
E3397_RS10415	COG0727	PFAM Uncharacterised protein family (UPF0153)
E3397_RS10425	COG3546	catalase activity
E3397_RS10430	COG3685	Protein conserved in bacteria
E3397_RS10435	COG3685	Protein conserved in bacteria
E3397_RS10440	COG3729	General stress protein
E3397_RS10455	COG0134	indole-3-glycerol-phosphate synthase activity
E3397_RS10455	COG0135	phosphoribosylanthranilate isomerase activity
E3397_RS10480	COG0009	L-threonylcarbamoyladenylate synthase
E3397_RS10495	COG1028	Short-chain dehydrogenase reductase Sdr
E3397_RS10500	COG0616	signal peptide processing
E3397_RS10545	COG0671	phosphoesterase, PA-phosphatase related
E3397_RS10550	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E3397_RS10555	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E3397_RS10575	COG1349	DNA-binding transcription factor activity
E3397_RS10585	COG5001	Diguanylate cyclase
E3397_RS10595	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3397_RS10595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3397_RS10650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E3397_RS10655	COG1842	Phage shock protein A
E3397_RS10665	COG1983	PspC domain protein
E3397_RS10675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3397_RS10680	COG3106	COG3106 Predicted ATPase
E3397_RS10700	COG4948	Mandelate Racemase Muconate Lactonizing
E3397_RS10705	COG2866	Carboxypeptidase
E3397_RS10710	COG4166	transmembrane transport
E3397_RS10720	COG0583	DNA-binding transcription factor activity
E3397_RS10725	COG0656	L-ascorbic acid biosynthetic process
E3397_RS10730	COG1028	Short-chain dehydrogenase reductase Sdr
E3397_RS10735	COG1309	transcriptional regulator
E3397_RS10770	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E3397_RS10790	COG0668	transmembrane transport
E3397_RS10795	COG3182	Iron-regulated membrane protein
E3397_RS10815	COG2840	Smr protein MutS2
E3397_RS10820	COG0840	transmembrane signaling receptor activity
E3397_RS10835	COG0513	Belongs to the DEAD box helicase family
E3397_RS10850	COG2076	Multidrug Resistance protein
E3397_RS10860	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3397_RS10860	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3397_RS10860	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3397_RS10860	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3397_RS10870	COG3042	response to heat
E3397_RS10875	COG3187	Heat shock protein
E3397_RS10880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E3397_RS10885	COG2911	Protein conserved in bacteria
E3397_RS10895	COG3784	Protein of unknown function (DUF1318)
E3397_RS10910	COG1643	Atp-dependent helicase
E3397_RS10915	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E3397_RS10920	COG3038	cytochrome b561
E3397_RS10925	COG0500	methyltransferase
E3397_RS10935	COG0765	amino acid transport
E3397_RS10945	COG0765	amino acid transport
E3397_RS10950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3397_RS10985	COG0840	transmembrane signaling receptor activity
E3397_RS10990	COG0583	DNA-binding transcription factor activity
E3397_RS10995	COG5383	Protein conserved in bacteria
E3397_RS11000	COG2272	Belongs to the type-B carboxylesterase lipase family
E3397_RS11005	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
E3397_RS11010	COG2353	YceI-like domain
E3397_RS11015	COG1304	FMN binding
E3397_RS11025	COG1349	DNA-binding transcription factor activity
E3397_RS11030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3397_RS11035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS11040	COG0434	BtpA family
E3397_RS11045	COG3775	system Galactitol-specific IIC component
E3397_RS11050	COG3414	Phosphotransferase system galactitol-specific IIB component
E3397_RS11060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3397_RS11065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E3397_RS11070	COG1275	C4-dicarboxylate transporter malic acid transport protein
E3397_RS11075	COG0500	methyltransferase
E3397_RS11085	COG3135	benzoate transporter
E3397_RS11090	COG1396	sequence-specific DNA binding
E3397_RS11095	COG0826	peptidase U32
E3397_RS11120	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E3397_RS11125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3397_RS11165	COG3238	Protein conserved in bacteria
E3397_RS11175	COG2130	NADP-dependent
E3397_RS11180	COG1802	Transcriptional regulator
E3397_RS11185	COG4772	TonB-dependent receptor
E3397_RS11190	COG3391	amine dehydrogenase activity
E3397_RS11225	COG2181	nitrate reductase activity
E3397_RS11230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E3397_RS11235	COG1140	nitrate reductase beta subunit
E3397_RS11240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3397_RS11280	COG0437	4 iron, 4 sulfur cluster binding
E3397_RS11285	COG2864	formate dehydrogenase
E3397_RS11290	COG1064	alcohol dehydrogenase
E3397_RS11310	COG1764	response to oxidative stress
E3397_RS11325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E3397_RS11340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E3397_RS11345	COG1757	Na H antiporter
E3397_RS11350	COG1609	Transcriptional regulator
E3397_RS11395	COG0251	oxidation-reduction process
E3397_RS11400	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E3397_RS11425	COG2271	Major facilitator Superfamily
E3397_RS11430	COG1063	alcohol dehydrogenase
E3397_RS11435	COG2186	Transcriptional regulator
E3397_RS11445	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E3397_RS11450	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E3397_RS11475	COG1773	rubredoxin
E3397_RS11500	COG3781	membrane
E3397_RS11515	COG1012	belongs to the aldehyde dehydrogenase family
E3397_RS11520	COG0583	DNA-binding transcription factor activity
E3397_RS11555	COG2814	Major facilitator Superfamily
E3397_RS11565	COG3111	PFAM Bacterial OB fold (BOF) protein
E3397_RS11570	COG1546	Belongs to the CinA family
E3397_RS11575	COG3729	General stress protein
E3397_RS11590	COG4221	oxidoreductase activity
E3397_RS11595	COG1802	Transcriptional regulator
E3397_RS11605	COG0246	Mannitol dehydrogenase
E3397_RS11610	COG0477	Major facilitator Superfamily
E3397_RS11615	COG1063	alcohol dehydrogenase
E3397_RS11635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3397_RS11650	COG0243	molybdopterin cofactor binding
E3397_RS11655	COG0243	molybdopterin cofactor binding
E3397_RS11660	COG0437	4 iron, 4 sulfur cluster binding
E3397_RS11665	COG3302	dmso reductase anchor subunit
E3397_RS11705	COG1940	carbohydrate kinase activity
E3397_RS11710	COG0583	DNA-binding transcription factor activity
E3397_RS11715	COG2814	Major facilitator Superfamily
E3397_RS11725	COG3591	Belongs to the peptidase S1B family
E3397_RS11745	COG0628	permease
E3397_RS11750	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E3397_RS11755	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E3397_RS11765	COG0531	amino acid
E3397_RS11770	COG3136	membrane protein required for alginate biosynthesis
E3397_RS11775	COG0745	RESPONSE REGULATOR receiver
E3397_RS11785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3397_RS11790	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
E3397_RS11795	COG2205	protein histidine kinase activity
E3397_RS11820	COG5339	Protein conserved in bacteria
E3397_RS11830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E3397_RS11840	COG0673	inositol 2-dehydrogenase activity
E3397_RS11890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3397_RS11900	COG0625	glutathione transferase activity
E3397_RS11920	COG3895	Periplasmic Protein
E3397_RS11945	COG1566	PFAM secretion protein HlyD family protein
E3397_RS11960	COG4989	oxidoreductase activity
E3397_RS11965	COG3313	Fe-S protein
E3397_RS11970	COG1309	transcriptional regulator
E3397_RS11975	COG1902	pentaerythritol trinitrate reductase activity
E3397_RS11995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E3397_RS12000	COG0791	NLP P60 protein
E3397_RS12020	COG0583	DNA-binding transcription factor activity
E3397_RS12025	COG2814	Major facilitator Superfamily
E3397_RS12030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E3397_RS12035	COG0307	riboflavin synthase, alpha
E3397_RS12215	COG0789	Transcriptional regulator
E3397_RS12220	COG3272	Protein of unknown function (DUF1722)
E3397_RS12255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS12265	COG2267	carboxylic ester hydrolase activity
E3397_RS12270	COG0531	amino acid
E3397_RS12290	COG4238	major outer membrane lipoprotein
E3397_RS12295	COG1376	ErfK ybiS ycfS ynhG family protein
E3397_RS12310	COG0719	Fe-S assembly protein
E3397_RS12315	COG0396	ATPase activity
E3397_RS12320	COG0719	Fe-S assembly protein
E3397_RS12325	COG0316	Belongs to the HesB IscA family
E3397_RS12330	COG1823	symporter activity
E3397_RS12340	COG2050	protein possibly involved in aromatic compounds catabolism
E3397_RS12345	COG0277	FAD linked oxidase domain protein
E3397_RS12345	COG0247	lactate metabolic process
E3397_RS12350	COG0628	permease
E3397_RS12365	COG0738	Major facilitator superfamily
E3397_RS12370	COG2271	Major facilitator Superfamily
E3397_RS12385	COG4670	ketone body catabolic process
E3397_RS12390	COG1960	acyl-CoA dehydrogenase activity
E3397_RS12395	COG2207	Transcriptional regulator
E3397_RS12395	COG1917	Cupin 2, conserved barrel domain protein
E3397_RS12400	COG2086	electron transfer activity
E3397_RS12405	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E3397_RS12410	COG0644	oxidoreductase
E3397_RS12415	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3397_RS12420	COG0318	PFAM AMP-dependent synthetase and ligase
E3397_RS12425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3397_RS12425	COG0574	Belongs to the PEP-utilizing enzyme family
E3397_RS12440	COG4256	Hemin uptake protein
E3397_RS12455	COG0791	NLP P60 protein
E3397_RS12465	COG0386	Belongs to the glutathione peroxidase family
E3397_RS12530	COG3137	Salt-induced outer membrane protein
E3397_RS12535	COG1105	Belongs to the carbohydrate kinase PfkB family
E3397_RS12545	COG3001	Fructosamine kinase
E3397_RS12555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3397_RS12560	COG1988	membrane-bound metal-dependent
E3397_RS12565	COG1823	symporter activity
E3397_RS12575	COG0753	catalase activity
E3397_RS12585	COG1486	melibiose metabolic process
E3397_RS12590	COG1917	Cupin 2, conserved barrel domain protein
E3397_RS12590	COG2169	Transcriptional regulator
E3397_RS12595	COG1447	Phosphotransferase system cellobiose-specific component IIA
E3397_RS12600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E3397_RS12605	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E3397_RS12615	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3397_RS12625	COG0322	excinuclease ABC activity
E3397_RS12630	COG3678	ATP-independent chaperone mediated protein folding
E3397_RS12665	COG0494	nUDIX hydrolase
E3397_RS12680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E3397_RS12690	COG0778	Nitroreductase
E3397_RS12695	COG0616	signal peptide processing
E3397_RS12700	COG0252	asparaginase activity
E3397_RS12705	COG1335	isochorismatase
E3397_RS12710	COG2814	Major facilitator Superfamily
E3397_RS12715	COG1349	DNA-binding transcription factor activity
E3397_RS12720	COG0667	Aldo Keto reductase
E3397_RS12725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS12730	COG0191	fructose-bisphosphate aldolase activity
E3397_RS12735	COG1063	alcohol dehydrogenase
E3397_RS12740	COG2271	Major facilitator Superfamily
E3397_RS12745	COG1063	alcohol dehydrogenase
E3397_RS12750	COG3139	Protein of unknown function (DUF1315)
E3397_RS12770	COG0656	L-ascorbic acid biosynthetic process
E3397_RS12775	COG0641	radical SAM
E3397_RS12780	COG3713	MltA-interacting MipA family protein
E3397_RS12785	COG2766	serine protein kinase
E3397_RS12800	COG2199	diguanylate cyclase activity
E3397_RS12805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3397_RS12820	COG2207	Transcriptional regulator
E3397_RS12825	COG2807	transmembrane transport
E3397_RS12830	COG3189	MarR family transcriptional regulator
E3397_RS12840	COG3042	response to heat
E3397_RS12850	COG2261	transglycosylase associated protein
E3397_RS12870	COG3615	Tellurite resistance protein tehB
E3397_RS12880	COG1605	Chorismate mutase
E3397_RS12895	COG0789	Transcriptional regulator
E3397_RS12910	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3397_RS12925	COG0668	transmembrane transport
E3397_RS12930	COG1124	(ABC) transporter
E3397_RS12960	COG3038	cytochrome b561
E3397_RS12975	COG0071	Belongs to the small heat shock protein (HSP20) family
E3397_RS13045	COG0538	isocitrate dehydrogenase activity
E3397_RS13050	COG1187	pseudouridine synthase activity
E3397_RS13075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E3397_RS13090	COG2850	peptidyl-arginine hydroxylation
E3397_RS13120	COG1177	transmembrane transport
E3397_RS13140	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3397_RS13145	COG1136	(ABC) transporter
E3397_RS13150	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3397_RS13155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E3397_RS13160	COG1376	ErfK ybiS ycfS ynhG family protein
E3397_RS13160	COG1388	LysM domain
E3397_RS13170	COG1309	transcriptional regulator
E3397_RS13175	COG3134	Outer membrane lipoprotein
E3397_RS13180	COG1252	NADH dehydrogenase
E3397_RS13205	COG5633	Lipoprotein
E3397_RS13210	COG0537	adenosine 5'-monophosphoramidase activity
E3397_RS13215	COG4773	Receptor
E3397_RS13225	COG0084	hydrolase, TatD family'
E3397_RS13230	COG0470	DNA polymerase III
E3397_RS13240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E3397_RS13245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E3397_RS13250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3397_RS13315	COG1530	ribonuclease E activity
E3397_RS13405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3397_RS13415	COG2999	glutathione oxidoreductase activity
E3397_RS13450	COG3038	cytochrome b561
E3397_RS13465	COG1560	Kdo2-lipid A biosynthetic process
E3397_RS13480	COG5645	(Lipo)protein
E3397_RS13505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3397_RS13560	COG3381	protein complex oligomerization
E3397_RS13585	COG0673	inositol 2-dehydrogenase activity
E3397_RS13590	COG2814	Major facilitator Superfamily
E3397_RS13610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3397_RS13615	COG1737	Transcriptional regulator
E3397_RS13620	COG1702	phosphate starvation-inducible protein PhoH
E3397_RS13640	COG1309	transcriptional regulator
E3397_RS13645	COG3729	General stress protein
E3397_RS13665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3397_RS13670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3397_RS13670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E3397_RS13675	COG4232	protein-disulfide reductase activity
E3397_RS13725	COG3971	2-oxopent-4-enoate hydratase activity
E3397_RS13735	COG3384	dioxygenase
E3397_RS13740	COG1012	belongs to the aldehyde dehydrogenase family
E3397_RS13750	COG1846	Transcriptional regulator
E3397_RS13755	COG2368	4-hydroxyphenylacetate
E3397_RS13770	COG0745	RESPONSE REGULATOR receiver
E3397_RS13775	COG2205	protein histidine kinase activity
E3397_RS13825	COG0670	Belongs to the BI1 family
E3397_RS13845	COG1881	PFAM PEBP family protein
E3397_RS13860	COG1832	CoA-binding protein
E3397_RS13875	COG0210	DNA helicase
E3397_RS13880	COG3304	Inner membrane component domain
E3397_RS13885	COG1289	transmembrane transporter activity
E3397_RS13890	COG3070	regulator of competence-specific genes
E3397_RS13910	COG1067	ATP-dependent peptidase activity
E3397_RS13920	COG3130	regulation of translation
E3397_RS13925	COG3009	Protein conserved in bacteria
E3397_RS13930	COG3008	intermembrane lipid transfer
E3397_RS13930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3397_RS13935	COG2995	paraquat-inducible protein a
E3397_RS13940	COG0488	(ABC) transporter
E3397_RS13950	COG3217	Mosc domain protein beta barrel domain protein
E3397_RS13950	COG0633	Ferredoxin
E3397_RS13965	COG0308	aminopeptidase N
E3397_RS13995	COG5301	cellulose 1,4-beta-cellobiosidase activity
E3397_RS14105	COG4220	transposase activity
E3397_RS14145	COG0484	heat shock protein binding
E3397_RS14185	COG1484	DNA-dependent DNA replication
E3397_RS14230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3397_RS14250	COG0582	viral genome integration into host DNA
E3397_RS14260	COG1115	amino acid carrier protein
E3397_RS14275	COG1522	sequence-specific DNA binding
E3397_RS14280	COG0017	Asparaginyl-tRNA synthetase
E3397_RS14285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3397_RS14295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3397_RS14300	COG3108	Peptidase M15
E3397_RS14305	COG2989	Protein conserved in bacteria
E3397_RS14320	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E3397_RS14330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3397_RS14335	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E3397_RS14340	COG3173	Aminoglycoside phosphotransferase
E3397_RS14360	COG3214	Protein conserved in bacteria
E3397_RS14375	COG0658	competence protein
E3397_RS14375	COG2333	competence protein COMEC
E3397_RS14385	COG0539	negative regulation of cytoplasmic translation
E3397_RS14395	COG0501	Belongs to the peptidase M48B family
E3397_RS14410	COG2323	membrane
E3397_RS14415	COG1944	ATP diphosphatase activity
E3397_RS14420	COG2116	formate transmembrane transporter activity
E3397_RS14425	COG1882	Formate acetyltransferase
E3397_RS14440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3397_RS14445	COG0531	amino acid
E3397_RS14455	COG3302	dmso reductase anchor subunit
E3397_RS14460	COG0437	4 iron, 4 sulfur cluster binding
E3397_RS14465	COG0243	molybdopterin cofactor binding
E3397_RS14475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3397_RS14495	COG0492	ferredoxin-NADP+ reductase activity
E3397_RS14500	COG4988	ABC transporter
E3397_RS14505	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3397_RS14525	COG0583	DNA-binding transcription factor activity
E3397_RS14535	COG1335	isochorismatase
E3397_RS14550	COG0542	response to heat
E3397_RS14560	COG1278	Cold shock
E3397_RS14570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3397_RS14575	COG2990	Protein conserved in bacteria
E3397_RS14580	COG3593	DNA synthesis involved in DNA repair
E3397_RS14585	COG2431	L-lysine efflux transmembrane transporter activity
E3397_RS14595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E3397_RS14600	COG0028	Belongs to the TPP enzyme family
E3397_RS14605	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E3397_RS14610	COG0702	epimerase
E3397_RS14615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3397_RS14620	COG3023	N-Acetylmuramoyl-L-alanine amidase
E3397_RS14635	COG1126	abc transporter atp-binding protein
E3397_RS14640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3397_RS14645	COG4215	(ABC) transporter
E3397_RS14650	COG4160	amino acid transport
E3397_RS14655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3397_RS14685	COG1177	transmembrane transport
E3397_RS14690	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3397_RS14695	COG3842	ATPase activity
E3397_RS14700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3397_RS14745	COG3226	Transcriptional regulator
E3397_RS14750	COG0738	Major facilitator superfamily
E3397_RS14755	COG0561	phosphatase activity
E3397_RS14760	COG2814	Major facilitator Superfamily
E3397_RS14765	COG0671	phosphoesterase, PA-phosphatase related
E3397_RS14770	COG1349	DNA-binding transcription factor activity
E3397_RS14775	COG1686	Belongs to the peptidase S11 family
E3397_RS14780	COG0625	glutathione transferase activity
E3397_RS14785	COG2133	pyrroloquinoline quinone binding
E3397_RS14795	COG2610	gluconate transmembrane transporter activity
E3397_RS14800	COG0583	DNA-binding transcription factor activity
E3397_RS14815	COG1960	acyl-CoA dehydrogenase activity
E3397_RS14835	COG2301	Belongs to the HpcH HpaI aldolase family
E3397_RS14885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3397_RS14890	COG1882	Formate acetyltransferase
E3397_RS14895	COG0561	phosphatase activity
E3397_RS14905	COG0488	(ABC) transporter
E3397_RS14910	COG1376	ErfK ybiS ycfS ynhG family protein
E3397_RS14915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E3397_RS14930	COG2194	sulfuric ester hydrolase activity
E3397_RS14935	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E3397_RS14950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3397_RS14955	COG0765	amino acid transport
E3397_RS14960	COG1126	abc transporter atp-binding protein
E3397_RS14965	COG0668	transmembrane transport
E3397_RS14975	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3397_RS14985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3397_RS14995	COG0513	Belongs to the DEAD box helicase family
E3397_RS15000	COG1309	transcriptional regulator
E3397_RS15010	COG1131	(ABC) transporter
E3397_RS15015	COG0842	Transport permease protein
E3397_RS15020	COG0842	Transport permease protein
E3397_RS15030	COG3568	Endonuclease Exonuclease Phosphatase
E3397_RS15035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3397_RS15040	COG0392	lysyltransferase activity
E3397_RS15060	COG0670	Belongs to the BI1 family
E3397_RS15070	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E3397_RS15080	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3397_RS15140	COG1881	PFAM PEBP family protein
E3397_RS15170	COG4677	pectinesterase activity
E3397_RS15180	COG0561	phosphatase activity
E3397_RS15190	COG4149	molybdate abc transporter
E3397_RS15195	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3397_RS15205	COG3585	molybdate ion transport
E3397_RS15205	COG2005	Transcriptional regulator
E3397_RS15210	COG1119	ATPase activity
E3397_RS15235	COG2017	converts alpha-aldose to the beta-anomer
E3397_RS15245	COG1120	ATPase activity
E3397_RS15250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3397_RS15265	COG0511	ligase activity, forming carbon-carbon bonds
E3397_RS15265	COG5016	pyruvate
E3397_RS15275	COG0471	metal ion transport
E3397_RS15275	COG0490	domain, Protein
E3397_RS15280	COG0583	DNA-binding transcription factor activity
E3397_RS15285	COG0583	DNA-binding transcription factor activity
E3397_RS15295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3397_RS15295	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3397_RS15300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E3397_RS15310	COG1230	cation diffusion facilitator family transporter
E3397_RS15350	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E3397_RS15355	COG2885	chlorophyll binding
E3397_RS15365	COG3064	Membrane
E3397_RS15370	COG0848	biopolymer transport protein
E3397_RS15375	COG0811	peptide transport
E3397_RS15380	COG0824	Thioesterase
E3397_RS15385	COG3790	cyd operon protein YbgE
E3397_RS15390	COG4890	Cyd operon protein YbgT
E3397_RS15395	COG1294	oxidase, subunit
E3397_RS15400	COG1271	oxidase subunit
E3397_RS15405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3397_RS15415	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3397_RS15420	COG0567	Dehydrogenase, E1 component
E3397_RS15435	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E3397_RS15450	COG3180	Ammonia monooxygenase
E3397_RS15465	COG1984	allophanate hydrolase subunit 2
E3397_RS15470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3397_RS15500	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
E3397_RS15510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
E3397_RS15515	COG2205	protein histidine kinase activity
E3397_RS15520	COG0745	RESPONSE REGULATOR receiver
E3397_RS15530	COG1982	Orn Lys Arg decarboxylase major
E3397_RS15535	COG0531	amino acid
E3397_RS15545	COG0033	Phosphoglucomutase
E3397_RS15555	COG0596	Alpha beta hydrolase
E3397_RS15570	COG0735	belongs to the Fur family
E3397_RS15575	COG0583	DNA-binding transcription factor activity
E3397_RS15580	COG1053	succinate dehydrogenase
E3397_RS15620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3397_RS15625	COG1846	Transcriptional regulator
E3397_RS15625	COG1940	carbohydrate kinase activity
E3397_RS15630	COG0647	UMP catabolic process
E3397_RS15635	COG0367	asparagine synthase
E3397_RS15675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3397_RS15685	COG1702	phosphate starvation-inducible protein PhoH
E3397_RS15710	COG0765	amino acid transport
E3397_RS15715	COG0765	amino acid transport
E3397_RS15720	COG1126	abc transporter atp-binding protein
E3397_RS15735	COG0443	Heat shock 70 kDa protein
E3397_RS15740	COG2214	Heat shock protein DnaJ domain protein
E3397_RS15750	COG2214	Heat shock protein DnaJ domain protein
E3397_RS15765	COG2888	peptidyl-tyrosine sulfation
E3397_RS15770	COG3829	transcription factor binding
E3397_RS15770	COG3290	protein histidine kinase activity
E3397_RS15800	COG1466	dna polymerase III delta subunit
E3397_RS15810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3397_RS15820	COG0799	negative regulation of ribosome biogenesis
E3397_RS15830	COG0768	penicillin binding
E3397_RS15835	COG0772	Belongs to the SEDS family
E3397_RS15845	COG1686	Belongs to the peptidase S11 family
E3397_RS15860	COG0583	DNA-binding transcription factor activity
E3397_RS15875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3397_RS15895	COG3069	C4-dicarboxylate transmembrane transporter activity
E3397_RS15900	COG4565	transcriptional regulatory protein
E3397_RS15905	COG3290	protein histidine kinase activity
E3397_RS15910	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E3397_RS15920	COG2301	Belongs to the HpcH HpaI aldolase family
E3397_RS15925	COG3051	citrate lyase alpha subunit
E3397_RS15940	COG0471	metal ion transport
E3397_RS15945	COG3719	Belongs to the RNase T2 family
E3397_RS15950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3397_RS15955	COG1063	alcohol dehydrogenase
E3397_RS15975	COG0243	molybdopterin cofactor binding
E3397_RS15995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3397_RS16005	COG3969	phosphoadenosine phosphosulfate
E3397_RS16010	COG1475	DNA binding
E3397_RS16015	COG0436	Aminotransferase
E3397_RS16020	COG0371	Dehydrogenase
E3397_RS16025	COG2879	small protein
E3397_RS16030	COG1966	Carbon starvation protein
E3397_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
E3397_RS16045	COG3433	isochorismatase activity
E3397_RS16045	COG1535	isochorismatase
E3397_RS16050	COG1021	2,3-dihydroxybenzoate-AMP ligase
E3397_RS16055	COG1169	isochorismate synthase
E3397_RS16060	COG4592	Periplasmic binding protein
E3397_RS16070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3397_RS16075	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3397_RS16080	COG1120	ATPase activity
E3397_RS16085	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E3397_RS16090	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E3397_RS16090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E3397_RS16095	COG3251	PFAM MbtH domain protein
E3397_RS16100	COG2382	esterase
E3397_RS16105	COG4771	TonB-dependent receptor
E3397_RS16135	COG2315	Protein conserved in bacteria
E3397_RS16160	COG3716	PTS system mannose fructose sorbose family IID component
E3397_RS16170	COG2222	sugar isomerase
E3397_RS16175	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E3397_RS16175	COG3933	PFAM sigma-54 factor interaction domain-containing protein
E3397_RS16185	COG0668	transmembrane transport
E3397_RS16190	COG1113	amino acid transport
E3397_RS16200	COG3059	membrane
E3397_RS16210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3397_RS16215	COG2207	Transcriptional regulator
E3397_RS16220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3397_RS16225	COG5002	protein histidine kinase activity
E3397_RS16235	COG2246	polysaccharide biosynthetic process
E3397_RS16240	COG0463	Glycosyl transferase, family 2
E3397_RS16265	COG0463	Glycosyl transferase, family 2
E3397_RS16270	COG2246	polysaccharide biosynthetic process
E3397_RS16285	COG0582	viral genome integration into host DNA
E3397_RS16360	COG2501	S4 domain
E3397_RS16365	COG1988	membrane-bound metal-dependent
E3397_RS16385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E3397_RS16395	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3397_RS16400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E3397_RS16405	COG0549	Belongs to the carbamate kinase family
E3397_RS16415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3397_RS16420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3397_RS16425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E3397_RS16430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3397_RS16435	COG3257	ureidoglycine aminohydrolase activity
E3397_RS16440	COG1929	Belongs to the glycerate kinase type-1 family
E3397_RS16445	COG2233	PERMEase
E3397_RS16455	COG1953	Uracil, thiamine, allantoin
E3397_RS16465	COG2084	Dehydrogenase
E3397_RS16470	COG3622	Belongs to the hyi family
E3397_RS16475	COG3960	tartronate-semialdehyde synthase activity
E3397_RS16510	COG1464	Belongs to the NlpA lipoprotein family
E3397_RS16520	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E3397_RS16525	COG4181	ATPase activity
E3397_RS16530	COG2755	lipolytic protein G-D-S-L family
E3397_RS16535	COG0300	oxidoreductase activity
E3397_RS16540	COG3118	belongs to the thioredoxin family
E3397_RS16545	COG0390	transport system, permease component
E3397_RS16550	COG4619	ABC transporter
E3397_RS16555	COG0330	HflC and HflK could
E3397_RS16560	COG1585	Membrane protein implicated in regulation of membrane protease activity
E3397_RS16570	COG2217	Heavy metal translocating P-type atpase
E3397_RS16580	COG3735	TraB family
E3397_RS16595	COG2223	nitrite transmembrane transporter activity
E3397_RS16600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E3397_RS16600	COG4651	solute:proton antiporter activity
E3397_RS16605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS16650	COG2832	Protein of unknown function (DUF454)
E3397_RS16655	COG3923	Primosomal replication protein n
E3397_RS16665	COG5464	transposase or invertase
E3397_RS16670	COG1196	nuclear chromosome segregation
E3397_RS16670	COG3264	Mechanosensitive ion channel
E3397_RS16675	COG1309	transcriptional regulator
E3397_RS16680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3397_RS16685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3397_RS16700	COG0110	maltose O-acetyltransferase activity
E3397_RS16720	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E3397_RS16730	COG3695	enzyme binding
E3397_RS16735	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E3397_RS16740	COG1946	Acyl-CoA thioesterase
E3397_RS16745	COG0004	ammonium transporteR
E3397_RS16750	COG0347	Belongs to the P(II) protein family
E3397_RS16755	COG1132	(ABC) transporter
E3397_RS16760	COG1132	(ABC) transporter
E3397_RS16765	COG1522	sequence-specific DNA binding
E3397_RS16780	COG4533	DNA binding
E3397_RS16790	COG0824	Thioesterase
E3397_RS16795	COG1555	photosystem II stabilization
E3397_RS16800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3397_RS16810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E3397_RS16835	COG0271	Belongs to the BolA IbaG family
E3397_RS16840	COG3056	Lipoprotein
E3397_RS16845	COG2223	nitrite transmembrane transporter activity
E3397_RS16850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E3397_RS16855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E3397_RS16860	COG1845	cytochrome c oxidase, subunit III
E3397_RS16865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E3397_RS16885	COG2814	Major facilitator Superfamily
E3397_RS16915	COG2188	Transcriptional regulator
E3397_RS16950	COG0142	geranyltranstransferase activity
E3397_RS16960	COG0667	Aldo Keto reductase
E3397_RS16965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E3397_RS16970	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E3397_RS16985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3397_RS16985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3397_RS16995	COG4238	major outer membrane lipoprotein
E3397_RS17030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3397_RS17040	COG1862	Preprotein translocase
E3397_RS17060	COG0450	alkyl hydroperoxide reductase
E3397_RS17065	COG0366	Alpha amylase catalytic
E3397_RS17080	COG5002	protein histidine kinase activity
E3397_RS17090	COG0420	3'-5' exonuclease activity
E3397_RS17095	COG0419	ATPase involved in DNA repair
E3397_RS17100	COG2814	Major facilitator Superfamily
E3397_RS17105	COG1940	carbohydrate kinase activity
E3397_RS17120	COG4126	flavin adenine dinucleotide binding
E3397_RS17140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E3397_RS17145	COG3706	GGDEF domain
E3397_RS17190	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E3397_RS17200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3397_RS17215	COG0113	porphobilinogen synthase activity
E3397_RS17250	COG1280	lysine exporter protein (LysE YggA)
E3397_RS17270	COG1294	oxidase, subunit
E3397_RS17275	COG1271	oxidase subunit
E3397_RS17295	COG2814	Major facilitator Superfamily
E3397_RS17305	COG0789	Transcriptional regulator
E3397_RS17315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3397_RS17360	COG2200	EAL domain
E3397_RS17375	COG3539	Fimbrial protein
E3397_RS17380	COG3121	Chaperone
E3397_RS17385	COG3188	usher protein
E3397_RS17420	COG0179	Fumarylacetoacetate (FAA) hydrolase
E3397_RS17435	COG2814	Major facilitator Superfamily
E3397_RS17460	COG0582	viral genome integration into host DNA
E3397_RS17500	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3397_RS17505	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E3397_RS17510	COG1690	Belongs to the RtcB family
E3397_RS17520	COG3034	peptidoglycan biosynthetic process
E3397_RS17525	COG0121	glutamine amidotransferase
E3397_RS17540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3397_RS17570	COG1522	sequence-specific DNA binding
E3397_RS17670	COG4983	Phage plasmid primase, P4 family domain protein
E3397_RS17700	COG3596	GTP binding
E3397_RS17710	COG2378	regulation of single-species biofilm formation
E3397_RS17720	COG2378	regulation of single-species biofilm formation
E3397_RS17765	COG2003	Belongs to the UPF0758 family
E3397_RS17830	COG2226	methyltransferase
E3397_RS17840	COG1388	LysM domain
E3397_RS17840	COG0741	lytic transglycosylase activity
E3397_RS17845	COG2226	methyltransferase
E3397_RS17855	COG2814	Major facilitator Superfamily
E3397_RS17860	COG0583	DNA-binding transcription factor activity
E3397_RS17900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3397_RS17925	COG1720	tRNA m6t6A37 methyltransferase activity
E3397_RS17935	COG3015	lipoprotein NlpE involved in copper resistance
E3397_RS17940	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E3397_RS17955	COG4568	rho-dependent transcription termination
E3397_RS17965	COG0346	lactoylglutathione lyase activity
E3397_RS17970	COG1982	Orn Lys Arg decarboxylase major
E3397_RS18030	COG0575	Belongs to the CDS family
E3397_RS18080	COG0477	Major facilitator Superfamily
E3397_RS18090	COG3835	regulator
E3397_RS18115	COG2860	membrane
E3397_RS18145	COG3539	Fimbrial protein
E3397_RS18150	COG3539	Fimbrial protein
E3397_RS18155	COG3121	Chaperone
E3397_RS18160	COG3188	usher protein
E3397_RS18180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3397_RS18185	COG1120	ATPase activity
E3397_RS18190	COG4774	siderophore transport
E3397_RS18195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3397_RS18200	COG1643	Atp-dependent helicase
E3397_RS18205	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E3397_RS18230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3397_RS18255	COG3121	Chaperone
E3397_RS18260	COG3188	usher protein
E3397_RS18265	COG3539	Fimbrial protein
E3397_RS18285	COG0726	polysaccharide deacetylase
E3397_RS18290	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS18310	COG3539	Fimbrial protein
E3397_RS18315	COG0842	Transport permease protein
E3397_RS18320	COG1131	(ABC) transporter
E3397_RS18325	COG0288	reversible hydration of carbon dioxide
E3397_RS18335	COG4993	Dehydrogenase
E3397_RS18340	COG2132	Multicopper oxidase
E3397_RS18360	COG1349	DNA-binding transcription factor activity
E3397_RS18430	COG3064	Membrane
E3397_RS18445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3397_RS18450	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3397_RS18455	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E3397_RS18470	COG2211	Major facilitator Superfamily
E3397_RS18475	COG3940	Belongs to the glycosyl hydrolase 43 family
E3397_RS18480	COG3725	Membrane protein required for beta-lactamase induction
E3397_RS18500	COG4969	Belongs to the N-Me-Phe pilin family
E3397_RS18505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3397_RS18510	COG1459	type II secretion system
E3397_RS18545	COG0494	nUDIX hydrolase
E3397_RS18565	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3397_RS18570	COG0849	cell division
E3397_RS18595	COG0772	Belongs to the SEDS family
E3397_RS18610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3397_RS18620	COG0768	penicillin binding
E3397_RS18710	COG0586	Pfam SNARE associated Golgi protein
E3397_RS18750	COG0417	DNA replication proofreading
E3397_RS18780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E3397_RS18815	COG3119	arylsulfatase activity
E3397_RS18840	COG2271	Major facilitator Superfamily
E3397_RS18845	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E3397_RS18850	COG0644	oxidoreductase
E3397_RS19000	COG1047	Peptidyl-prolyl cis-trans
E3397_RS19015	COG0196	riboflavin kinase activity
E3397_RS19040	COG0583	DNA-binding transcription factor activity
E3397_RS19060	COG0641	radical SAM
E3397_RS19065	COG3119	arylsulfatase activity
E3397_RS19075	COG0737	Belongs to the 5'-nucleotidase family
E3397_RS19090	COG0583	DNA-binding transcription factor activity
E3397_RS19110	COG3121	Chaperone
E3397_RS19115	COG3539	Fimbrial protein
E3397_RS19130	COG3188	usher protein
E3397_RS19195	COG4735	regulation of single-species biofilm formation
E3397_RS19200	COG1584	GPR1 FUN34 yaaH family protein
E3397_RS19205	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3397_RS19215	COG1115	amino acid carrier protein
E3397_RS19225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3397_RS19235	COG0527	aspartate kinase activity
E3397_RS19235	COG0460	homoserine dehydrogenase
E3397_RS19245	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E3397_RS19255	COG0745	RESPONSE REGULATOR receiver
E3397_RS19275	COG3121	Chaperone
E3397_RS19295	COG4452	Inner membrane protein CreD
E3397_RS19300	COG2205	protein histidine kinase activity
E3397_RS19305	COG0745	RESPONSE REGULATOR receiver
E3397_RS19310	COG3045	CreA protein
E3397_RS19315	COG2207	Transcriptional regulator
E3397_RS19315	COG3708	Transcriptional regulator
E3397_RS19340	COG0488	(ABC) transporter
E3397_RS19355	COG0560	Phosphoserine phosphatase
E3397_RS19360	COG3726	membrane protein affecting hemolysin expression
E3397_RS19375	COG3539	Fimbrial protein
E3397_RS19380	COG3121	Chaperone
E3397_RS19385	COG3188	usher protein
E3397_RS19415	COG1328	CTP reductase activity
E3397_RS19420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3397_RS19425	COG0084	hydrolase, TatD family'
E3397_RS19430	COG4667	esterase of the alpha-beta hydrolase superfamily
E3397_RS19440	COG2823	Periplasmic or secreted lipoprotein
E3397_RS19450	COG1011	Hydrolase
E3397_RS19460	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E3397_RS19490	COG3706	GGDEF domain
E3397_RS19495	COG4114	ferric iron reductase
E3397_RS19500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3397_RS19505	COG2197	response regulator
E3397_RS19510	COG2197	response regulator
E3397_RS19515	COG2966	Psort location CytoplasmicMembrane, score
E3397_RS19530	COG1484	DNA-dependent DNA replication
E3397_RS19545	COG0840	transmembrane signaling receptor activity
E3397_RS19550	COG1966	Carbon starvation protein
E3397_RS19555	COG2879	small protein
E3397_RS19560	COG0523	cobalamin synthesis protein
E3397_RS19605	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E3397_RS19610	COG0732	type I restriction modification DNA specificity domain
E3397_RS19615	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
E3397_RS19620	COG3586	endonuclease activity
E3397_RS19635	COG1012	belongs to the aldehyde dehydrogenase family
E3397_RS19640	COG5464	transposase or invertase
E3397_RS19650	COG2733	membrane
E3397_RS19655	COG0477	Major facilitator Superfamily
E3397_RS19660	COG3366	ferrous iron transmembrane transporter activity
E3397_RS19665	COG0700	Nucleoside recognition
E3397_RS19670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3397_RS19675	COG0583	DNA-binding transcription factor activity
E3397_RS19695	COG2186	Transcriptional regulator
E3397_RS19700	COG0412	Dienelactone hydrolase
E3397_RS19730	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3397_RS19825	COG0582	viral genome integration into host DNA
E3397_RS19835	COG1064	alcohol dehydrogenase
E3397_RS19840	COG3265	gluconokinase activity
E3397_RS19845	COG1063	alcohol dehydrogenase
E3397_RS19850	COG1028	Short-chain dehydrogenase reductase Sdr
E3397_RS19855	COG2610	gluconate transmembrane transporter activity
E3397_RS19860	COG1609	Transcriptional regulator
E3397_RS19865	COG0795	lipopolysaccharide-transporting ATPase activity
E3397_RS19870	COG0795	lipopolysaccharide-transporting ATPase activity
E3397_RS19880	COG2927	DNA polymerase III (CHI subunit)
E3397_RS19920	COG2731	YhcH YjgK YiaL family protein
E3397_RS19940	COG1288	antiporter activity
E3397_RS19945	COG1438	arginine binding
E3397_RS19990	COG1263	PTS System
E3397_RS19990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3397_RS19995	COG0366	Alpha amylase catalytic
E3397_RS20010	COG2026	Addiction module toxin, RelE StbE family
E3397_RS20015	COG3077	Addiction module antitoxin, RelB DinJ family
E3397_RS20020	COG3711	transcriptional antiterminator
E3397_RS20020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS20035	COG3964	amidohydrolase
E3397_RS20070	COG0312	modulator of DNA gyrase
E3397_RS20080	COG1082	Xylose isomerase domain protein TIM barrel
E3397_RS20090	COG2814	Major facilitator Superfamily
E3397_RS20095	COG0673	inositol 2-dehydrogenase activity
E3397_RS20100	COG3962	Belongs to the TPP enzyme family
E3397_RS20105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS20115	COG1082	Xylose isomerase domain protein TIM barrel
E3397_RS20120	COG5520	Belongs to the glycosyl hydrolase 30 family
E3397_RS20150	COG3718	enzyme involved in inositol metabolism
E3397_RS20155	COG2814	Major facilitator Superfamily
E3397_RS20155	COG0477	Major facilitator Superfamily
E3397_RS20160	COG2814	Major facilitator Superfamily
E3397_RS20160	COG0477	Major facilitator Superfamily
E3397_RS20165	COG0837	glucose binding
E3397_RS20165	COG1737	Transcriptional regulator
E3397_RS20170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E3397_RS20185	COG3964	amidohydrolase
E3397_RS20190	COG2271	Major facilitator Superfamily
E3397_RS20195	COG2105	PFAM AIG2 family protein
E3397_RS20215	COG1253	flavin adenine dinucleotide binding
E3397_RS20225	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E3397_RS20240	COG1733	regulation of RNA biosynthetic process
E3397_RS20245	COG0702	epimerase
E3397_RS20250	COG0697	spore germination
E3397_RS20260	COG1113	amino acid transport
E3397_RS20265	COG0545	Peptidyl-prolyl cis-trans isomerase
E3397_RS20270	COG3061	Opacity-associated protein A
E3397_RS20285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E3397_RS20355	COG1073	alpha beta
E3397_RS20360	COG3650	response to hydrogen peroxide
E3397_RS20370	COG1960	acyl-CoA dehydrogenase activity
E3397_RS20375	COG0754	glutathionylspermidine amidase activity
E3397_RS20380	COG5463	Belongs to the UPF0441 family
E3397_RS20385	COG3766	membrane
E3397_RS20400	COG1842	Phage shock protein A
E3397_RS20405	COG3789	protein conserved in bacteria
E3397_RS20430	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E3397_RS20435	COG0330	HflC and HflK could
E3397_RS20440	COG0330	HflC and HflK could
E3397_RS20445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E3397_RS20470	COG0802	atpase or kinase
E3397_RS20475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E3397_RS20475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3397_RS20500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3397_RS20520	COG1511	domain protein
E3397_RS20520	COG3264	Mechanosensitive ion channel
E3397_RS20535	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
E3397_RS20540	COG1053	succinate dehydrogenase
E3397_RS20545	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3397_RS20575	COG5510	response to toxic substance
E3397_RS20615	COG0531	amino acid
E3397_RS20620	COG3030	protein affecting phage T7 exclusion by the F plasmid
E3397_RS20625	COG1027	Aspartate ammonia-lyase
E3397_RS20630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3397_RS20645	COG1309	transcriptional regulator
E3397_RS20755	COG2197	response regulator
E3397_RS20780	COG3381	protein complex oligomerization
E3397_RS20785	COG3302	dmso reductase anchor subunit
E3397_RS20790	COG0437	4 iron, 4 sulfur cluster binding
E3397_RS20795	COG0243	molybdopterin cofactor binding
E3397_RS20800	COG3290	protein histidine kinase activity
E3397_RS20805	COG4565	transcriptional regulatory protein
E3397_RS20815	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3397_RS20820	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E3397_RS20820	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E3397_RS20835	COG2169	Transcriptional regulator
E3397_RS20840	COG1982	Orn Lys Arg decarboxylase major
E3397_RS20845	COG2207	Transcriptional regulator
E3397_RS20850	COG0531	amino acid
E3397_RS20880	COG2824	Alkylphosphonate utilization operon protein PhnA
E3397_RS20885	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E3397_RS20905	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E3397_RS20910	COG1301	dicarboxylic acid transport
E3397_RS20915	COG4235	cytochrome complex assembly
E3397_RS20920	COG3088	subunit of a heme lyase
E3397_RS20925	COG1138	Cytochrome C-type biogenesis protein
E3397_RS20930	COG3301	Polysulphide reductase, NrfD
E3397_RS20935	COG0437	4 iron, 4 sulfur cluster binding
E3397_RS20940	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E3397_RS20950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3397_RS20955	COG3162	membrane
E3397_RS20965	COG1346	cytolysis
E3397_RS20970	COG1380	Effector of murein hydrolase LrgA
E3397_RS20975	COG0583	DNA-binding transcription factor activity
E3397_RS20980	COG0025	NhaP-type Na H and K H
E3397_RS20985	COG2252	PERMEase
E3397_RS21005	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E3397_RS21065	COG2315	Protein conserved in bacteria
E3397_RS21075	COG3700	Belongs to the class B bacterial acid phosphatase family
E3397_RS21105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3397_RS21115	COG0735	belongs to the Fur family
E3397_RS21130	COG0534	Mate efflux family protein
E3397_RS21140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E3397_RS21190	COG3833	ABC-type maltose transport systems, permease component
E3397_RS21200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3397_RS21225	COG0527	aspartate kinase activity
E3397_RS21255	COG0561	phosphatase activity
E3397_RS21260	COG1349	DNA-binding transcription factor activity
E3397_RS21275	COG3122	Protein conserved in bacteria
E3397_RS21320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E3397_RS21425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3397_RS21430	COG2104	thiamine diphosphate biosynthetic process
E3397_RS21495	COG0250	Participates in transcription elongation, termination and antitermination
E3397_RS21605	COG0583	DNA-binding transcription factor activity
E3397_RS21645	COG2207	Transcriptional regulator
E3397_RS21650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3397_RS21655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E3397_RS21660	COG1882	Formate acetyltransferase
E3397_RS21665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3397_RS21670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3397_RS21675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS21675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3397_RS21675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3397_RS21685	COG0371	Dehydrogenase
E3397_RS21690	COG3738	Protein conserved in bacteria
E3397_RS21705	COG0737	Belongs to the 5'-nucleotidase family
E3397_RS21720	COG0668	transmembrane transport
E3397_RS21725	COG0460	homoserine dehydrogenase
E3397_RS21725	COG0527	aspartate kinase activity
E3397_RS21730	COG0626	cystathionine gamma-synthase activity
E3397_RS21755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3397_RS21760	COG1609	Transcriptional regulator
E3397_RS21765	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3397_RS21780	COG1575	Belongs to the MenA family. Type 1 subfamily
E3397_RS21795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3397_RS21805	COG1494	fructose-1,6-bisphosphatase
E3397_RS21815	COG3152	Membrane
E3397_RS21870	COG1070	Carbohydrate kinase
E3397_RS21890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3397_RS21900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS21905	COG2211	Major facilitator Superfamily
E3397_RS21910	COG2134	cdp-diacylglycerol pyrophosphatase
E3397_RS21930	COG3678	ATP-independent chaperone mediated protein folding
E3397_RS21935	COG0745	RESPONSE REGULATOR receiver
E3397_RS21940	COG2205	protein histidine kinase activity
E3397_RS21950	COG2258	MOSC domain
E3397_RS21955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E3397_RS21965	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E3397_RS22010	COG1454	alcohol dehydrogenase
E3397_RS22025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E3397_RS22055	COG0437	4 iron, 4 sulfur cluster binding
E3397_RS22060	COG2864	formate dehydrogenase
E3397_RS22075	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
E3397_RS22085	COG0456	acetyltransferase
E3397_RS22100	COG1011	Hydrolase
E3397_RS22105	COG1349	DNA-binding transcription factor activity
E3397_RS22110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS22120	COG3684	Belongs to the aldolase LacD family
E3397_RS22130	COG2017	converts alpha-aldose to the beta-anomer
E3397_RS22135	COG1501	Belongs to the glycosyl hydrolase 31 family
E3397_RS22180	COG0561	phosphatase activity
E3397_RS22235	COG0204	Acyl-transferase
E3397_RS22250	COG3084	Protein conserved in bacteria
E3397_RS22260	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3397_RS22300	COG1739	Uncharacterized protein family UPF0029
E3397_RS22345	COG0805	protein transport
E3397_RS22390	COG0641	radical SAM
E3397_RS22415	COG0561	phosphatase activity
E3397_RS22420	COG2267	carboxylic ester hydrolase activity
E3397_RS22475	COG1011	Hydrolase
E3397_RS22545	COG2959	enzyme of heme biosynthesis
E3397_RS22550	COG3071	HemY protein
E3397_RS22595	COG2244	polysaccharide biosynthetic process
E3397_RS22600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3397_RS22605	COG0456	acetyltransferase
E3397_RS22610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E3397_RS22615	COG1088	dTDP-glucose 4,6-dehydratase activity
E3397_RS22620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3397_RS22635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3397_RS22655	COG3118	belongs to the thioredoxin family
E3397_RS22675	COG3201	nicotinamide mononucleotide transporter
E3397_RS22725	COG3978	acetolactate synthase activity
E3397_RS22785	COG2186	Transcriptional regulator
E3397_RS22790	COG0477	Major facilitator Superfamily
E3397_RS22795	COG1609	Transcriptional regulator
E3397_RS22800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3397_RS22810	COG1172	Belongs to the binding-protein-dependent transport system permease family
E3397_RS22845	COG1522	sequence-specific DNA binding
E3397_RS22850	COG0716	FMN binding
E3397_RS22865	COG3312	ion transport
E3397_RS22925	COG4533	DNA binding
E3397_RS22930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E3397_RS22935	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E3397_RS22935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3397_RS22935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3397_RS22940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E3397_RS22945	COG0573	inorganic phosphate transmembrane transporter activity
E3397_RS22950	COG0581	inorganic phosphate transmembrane transporter activity
E3397_RS22960	COG0704	Plays a role in the regulation of phosphate uptake
E3397_RS22965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3397_RS22970	COG2252	PERMEase
E3397_RS22975	COG0431	NADPH-dependent FMN reductase
E3397_RS22980	COG2091	lysine biosynthetic process via aminoadipic acid
E3397_RS23240	COG2207	Transcriptional regulator
E3397_RS23300	COG3328	transposase activity
E3397_RS23320	COG2771	luxR family
E3397_RS23375	COG2135	peptidase activity