locus-tag	class	description
GW13_RS00015	COG0539	negative regulation of cytoplasmic translation
GW13_RS00040	COG1663	tetraacyldisaccharide 4'-kinase activity
GW13_RS00045	COG3214	Protein conserved in bacteria
GW13_RS00060	COG3173	Aminoglycoside phosphotransferase
GW13_RS00065	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GW13_RS00070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GW13_RS00080	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GW13_RS00090	COG2989	Protein conserved in bacteria
GW13_RS00100	COG3108	Peptidase M15
GW13_RS00105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GW13_RS00115	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GW13_RS00120	COG0017	Asparaginyl-tRNA synthetase
GW13_RS00130	COG0308	aminopeptidase N
GW13_RS00145	COG3217	Mosc domain protein beta barrel domain protein
GW13_RS00145	COG0633	Ferredoxin
GW13_RS00155	COG0488	(ABC) transporter
GW13_RS00160	COG2995	paraquat-inducible protein a
GW13_RS00165	COG3008	intermembrane lipid transfer
GW13_RS00165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GW13_RS00170	COG3009	Protein conserved in bacteria
GW13_RS00175	COG3130	regulation of translation
GW13_RS00185	COG1067	ATP-dependent peptidase activity
GW13_RS00205	COG3070	regulator of competence-specific genes
GW13_RS00210	COG1289	transmembrane transporter activity
GW13_RS00215	COG3304	Inner membrane component domain
GW13_RS00220	COG0210	DNA helicase
GW13_RS00235	COG1832	CoA-binding protein
GW13_RS00250	COG1881	PFAM PEBP family protein
GW13_RS00270	COG0670	Belongs to the BI1 family
GW13_RS00325	COG2205	protein histidine kinase activity
GW13_RS00330	COG0745	RESPONSE REGULATOR receiver
GW13_RS00350	COG2368	4-hydroxyphenylacetate
GW13_RS00355	COG1846	Transcriptional regulator
GW13_RS00365	COG1012	belongs to the aldehyde dehydrogenase family
GW13_RS00370	COG3384	dioxygenase
GW13_RS00385	COG3971	2-oxopent-4-enoate hydratase activity
GW13_RS00440	COG4232	protein-disulfide reductase activity
GW13_RS00445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GW13_RS00445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GW13_RS00450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GW13_RS00470	COG3729	General stress protein
GW13_RS00475	COG1309	transcriptional regulator
GW13_RS00505	COG1702	phosphate starvation-inducible protein PhoH
GW13_RS00575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GW13_RS00585	COG1418	mRNA catabolic process
GW13_RS00590	COG0270	DNA (cytosine-5-)-methyltransferase activity
GW13_RS00595	COG3727	T/G mismatch-specific endonuclease activity
GW13_RS00600	COG0697	spore germination
GW13_RS00605	COG2354	Protein conserved in bacteria
GW13_RS00610	COG5475	Uncharacterized small protein (DUF2158)
GW13_RS00715	COG0582	viral genome integration into host DNA
GW13_RS00765	COG4712	double-strand break repair protein
GW13_RS00830	COG0305	Participates in initiation and elongation during chromosome replication
GW13_RS00880	COG0484	heat shock protein binding
GW13_RS00915	COG3728	DNA packaging
GW13_RS00920	COG1783	phage Terminase large subunit
GW13_RS01100	COG0425	Belongs to the sulfur carrier protein TusA family
GW13_RS01165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GW13_RS01175	COG0765	amino acid transport
GW13_RS01180	COG1126	abc transporter atp-binding protein
GW13_RS01185	COG2197	response regulator
GW13_RS01195	COG2197	response regulator
GW13_RS01240	COG3012	SEC-C Motif Domain Protein
GW13_RS01240	COG3318	Belongs to the UPF0149 family
GW13_RS01245	COG0814	amino acid
GW13_RS01255	COG1528	Iron-storage protein
GW13_RS01265	COG1528	Iron-storage protein
GW13_RS01275	COG1172	Belongs to the binding-protein-dependent transport system permease family
GW13_RS01365	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GW13_RS01380	COG3102	Protein conserved in bacteria
GW13_RS01410	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GW13_RS01415	COG5301	cellulose 1,4-beta-cellobiosidase activity
GW13_RS01470	COG2135	peptidase activity
GW13_RS01475	COG1335	isochorismatase
GW13_RS01485	COG0494	nUDIX hydrolase
GW13_RS01520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GW13_RS01530	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GW13_RS01535	COG0739	heme binding
GW13_RS01545	COG1560	Kdo2-lipid A biosynthetic process
GW13_RS01555	COG1737	Transcriptional regulator
GW13_RS01565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GW13_RS01570	COG0129	dihydroxy-acid dehydratase activity
GW13_RS01575	COG0800	Aldolase
GW13_RS01585	COG3141	response to X-ray
GW13_RS01595	COG2979	Protein of unknown function (DUF533)
GW13_RS01600	COG1770	oligopeptidase
GW13_RS01605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GW13_RS01610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GW13_RS01620	COG2372	response to copper ion
GW13_RS01625	COG1276	copper resistance
GW13_RS01650	COG3328	transposase activity
GW13_RS01670	COG5562	phage envelope protein
GW13_RS01700	COG3008	intermembrane lipid transfer
GW13_RS01705	COG2995	paraquat-inducible protein a
GW13_RS01710	COG1956	GAF domain-containing protein
GW13_RS01740	COG2814	Major facilitator Superfamily
GW13_RS01745	COG1414	Transcriptional regulator
GW13_RS01775	COG0768	penicillin binding
GW13_RS01780	COG2226	methyltransferase
GW13_RS01800	COG3716	PTS system mannose fructose sorbose family IID component
GW13_RS01805	COG3715	PTS system
GW13_RS01810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS01810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GW13_RS01820	COG1253	flavin adenine dinucleotide binding
GW13_RS01825	COG2200	EAL domain
GW13_RS01830	COG1760	l-serine dehydratase
GW13_RS01850	COG0251	oxidation-reduction process
GW13_RS01855	COG1199	ATP-dependent helicase activity
GW13_RS01865	COG3065	identical protein binding
GW13_RS01880	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GW13_RS01890	COG2894	cell division
GW13_RS01905	COG0179	Fumarylacetoacetate (FAA) hydrolase
GW13_RS01940	COG2719	SpoVR family
GW13_RS01960	COG1619	proteins homologs of microcin C7 resistance protein MccF
GW13_RS01985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GW13_RS01995	COG1294	oxidase, subunit
GW13_RS02000	COG1271	oxidase subunit
GW13_RS02005	COG1773	rubredoxin
GW13_RS02010	COG1999	signal sequence binding
GW13_RS02015	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GW13_RS02020	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
GW13_RS02030	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GW13_RS02040	COG0012	GTP binding
GW13_RS02055	COG0659	secondary active sulfate transmembrane transporter activity
GW13_RS02105	COG0387	Pfam Sodium calcium exchanger
GW13_RS02110	COG4572	Cation transport regulator
GW13_RS02125	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GW13_RS02130	COG4932	domain protein
GW13_RS02135	COG2197	response regulator
GW13_RS02140	COG3850	Histidine kinase
GW13_RS02150	COG2223	nitrite transmembrane transporter activity
GW13_RS02155	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GW13_RS02160	COG1140	nitrate reductase beta subunit
GW13_RS02165	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GW13_RS02170	COG2181	nitrate reductase activity
GW13_RS02205	COG0788	formyltetrahydrofolate deformylase activity
GW13_RS02215	COG1752	Esterase of the alpha-beta hydrolase superfamily
GW13_RS02220	COG0745	RESPONSE REGULATOR receiver
GW13_RS02225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GW13_RS02240	COG1454	alcohol dehydrogenase
GW13_RS02240	COG1012	belongs to the aldehyde dehydrogenase family
GW13_RS02245	COG2095	MarC family integral membrane protein
GW13_RS02280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GW13_RS02295	COG2350	Protein conserved in bacteria
GW13_RS02320	COG0727	PFAM Uncharacterised protein family (UPF0153)
GW13_RS02330	COG3546	catalase activity
GW13_RS02335	COG3685	Protein conserved in bacteria
GW13_RS02340	COG3685	Protein conserved in bacteria
GW13_RS02345	COG3729	General stress protein
GW13_RS02385	COG0009	L-threonylcarbamoyladenylate synthase
GW13_RS02400	COG1028	Short-chain dehydrogenase reductase Sdr
GW13_RS02405	COG0616	signal peptide processing
GW13_RS02445	COG0671	phosphoesterase, PA-phosphatase related
GW13_RS02455	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GW13_RS02460	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GW13_RS02480	COG1349	DNA-binding transcription factor activity
GW13_RS02490	COG5001	Diguanylate cyclase
GW13_RS02505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GW13_RS02505	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GW13_RS02560	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GW13_RS02565	COG1842	Phage shock protein A
GW13_RS02575	COG1983	PspC domain protein
GW13_RS02585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GW13_RS02590	COG3106	COG3106 Predicted ATPase
GW13_RS02610	COG4948	Mandelate Racemase Muconate Lactonizing
GW13_RS02615	COG2866	Carboxypeptidase
GW13_RS02620	COG4166	transmembrane transport
GW13_RS02630	COG0583	DNA-binding transcription factor activity
GW13_RS02635	COG0656	L-ascorbic acid biosynthetic process
GW13_RS02640	COG1028	Short-chain dehydrogenase reductase Sdr
GW13_RS02645	COG1309	transcriptional regulator
GW13_RS02680	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GW13_RS02700	COG0668	transmembrane transport
GW13_RS02705	COG3182	Iron-regulated membrane protein
GW13_RS02725	COG2840	Smr protein MutS2
GW13_RS02735	COG0840	transmembrane signaling receptor activity
GW13_RS02750	COG0513	Belongs to the DEAD box helicase family
GW13_RS02760	COG0582	viral genome integration into host DNA
GW13_RS02770	COG2076	Multidrug Resistance protein
GW13_RS02785	COG1013	pyruvate-flavodoxin oxidoreductase activity
GW13_RS02785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GW13_RS02785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GW13_RS02785	COG0674	pyruvate-flavodoxin oxidoreductase activity
GW13_RS02790	COG3042	response to heat
GW13_RS02795	COG3187	Heat shock protein
GW13_RS02800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GW13_RS02805	COG2911	Protein conserved in bacteria
GW13_RS02815	COG3784	Protein of unknown function (DUF1318)
GW13_RS02830	COG1643	Atp-dependent helicase
GW13_RS02835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GW13_RS02840	COG3038	cytochrome b561
GW13_RS02845	COG0500	methyltransferase
GW13_RS02855	COG0765	amino acid transport
GW13_RS02865	COG0765	amino acid transport
GW13_RS02870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GW13_RS02905	COG0840	transmembrane signaling receptor activity
GW13_RS02910	COG0583	DNA-binding transcription factor activity
GW13_RS02915	COG5383	Protein conserved in bacteria
GW13_RS02920	COG2272	Belongs to the type-B carboxylesterase lipase family
GW13_RS02925	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GW13_RS02930	COG2353	YceI-like domain
GW13_RS02935	COG1304	FMN binding
GW13_RS02945	COG1349	DNA-binding transcription factor activity
GW13_RS02950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GW13_RS02955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS02960	COG0434	BtpA family
GW13_RS02965	COG3775	system Galactitol-specific IIC component
GW13_RS02970	COG3414	Phosphotransferase system galactitol-specific IIB component
GW13_RS02980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GW13_RS02985	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GW13_RS02990	COG1275	C4-dicarboxylate transporter malic acid transport protein
GW13_RS02995	COG0500	methyltransferase
GW13_RS03005	COG3135	benzoate transporter
GW13_RS03010	COG1396	sequence-specific DNA binding
GW13_RS03015	COG0826	peptidase U32
GW13_RS03040	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GW13_RS03045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GW13_RS03085	COG3238	Protein conserved in bacteria
GW13_RS03095	COG2130	NADP-dependent
GW13_RS03100	COG1802	Transcriptional regulator
GW13_RS03105	COG4772	TonB-dependent receptor
GW13_RS03110	COG3391	amine dehydrogenase activity
GW13_RS03145	COG2181	nitrate reductase activity
GW13_RS03150	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GW13_RS03155	COG1140	nitrate reductase beta subunit
GW13_RS03160	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GW13_RS03200	COG0243	molybdopterin cofactor binding
GW13_RS03200	COG3383	formate dehydrogenase (NAD+) activity
GW13_RS03205	COG3383	formate dehydrogenase (NAD+) activity
GW13_RS03205	COG0243	molybdopterin cofactor binding
GW13_RS03210	COG0437	4 iron, 4 sulfur cluster binding
GW13_RS03215	COG2864	formate dehydrogenase
GW13_RS03220	COG1064	alcohol dehydrogenase
GW13_RS03240	COG1764	response to oxidative stress
GW13_RS03260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GW13_RS03275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GW13_RS03280	COG1757	Na H antiporter
GW13_RS03285	COG1609	Transcriptional regulator
GW13_RS03320	COG0251	oxidation-reduction process
GW13_RS03325	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GW13_RS03350	COG2271	Major facilitator Superfamily
GW13_RS03355	COG1063	alcohol dehydrogenase
GW13_RS03360	COG2186	Transcriptional regulator
GW13_RS03370	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GW13_RS03375	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GW13_RS03400	COG1773	rubredoxin
GW13_RS03425	COG3781	membrane
GW13_RS03440	COG1012	belongs to the aldehyde dehydrogenase family
GW13_RS03445	COG0583	DNA-binding transcription factor activity
GW13_RS03480	COG2814	Major facilitator Superfamily
GW13_RS03485	COG3111	PFAM Bacterial OB fold (BOF) protein
GW13_RS03490	COG1546	Belongs to the CinA family
GW13_RS03495	COG3729	General stress protein
GW13_RS03510	COG4221	oxidoreductase activity
GW13_RS03515	COG1802	Transcriptional regulator
GW13_RS03525	COG0246	Mannitol dehydrogenase
GW13_RS03530	COG0477	Major facilitator Superfamily
GW13_RS03535	COG1063	alcohol dehydrogenase
GW13_RS03555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GW13_RS03570	COG0243	molybdopterin cofactor binding
GW13_RS03575	COG0243	molybdopterin cofactor binding
GW13_RS03580	COG0437	4 iron, 4 sulfur cluster binding
GW13_RS03585	COG3302	dmso reductase anchor subunit
GW13_RS03625	COG1940	carbohydrate kinase activity
GW13_RS03635	COG0583	DNA-binding transcription factor activity
GW13_RS03640	COG2814	Major facilitator Superfamily
GW13_RS03650	COG3591	Belongs to the peptidase S1B family
GW13_RS03670	COG0628	permease
GW13_RS03675	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GW13_RS03680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GW13_RS03695	COG0531	amino acid
GW13_RS03700	COG3136	membrane protein required for alginate biosynthesis
GW13_RS03705	COG0745	RESPONSE REGULATOR receiver
GW13_RS03715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GW13_RS03720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GW13_RS03725	COG2205	protein histidine kinase activity
GW13_RS03750	COG5339	Protein conserved in bacteria
GW13_RS03755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GW13_RS03755	COG1263	PTS System
GW13_RS03765	COG0673	inositol 2-dehydrogenase activity
GW13_RS03815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GW13_RS03825	COG0625	glutathione transferase activity
GW13_RS03845	COG3895	Periplasmic Protein
GW13_RS03870	COG1566	PFAM secretion protein HlyD family protein
GW13_RS03885	COG4989	oxidoreductase activity
GW13_RS03890	COG3313	Fe-S protein
GW13_RS03895	COG1309	transcriptional regulator
GW13_RS03900	COG1902	pentaerythritol trinitrate reductase activity
GW13_RS03920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GW13_RS03925	COG0791	NLP P60 protein
GW13_RS03945	COG0583	DNA-binding transcription factor activity
GW13_RS03950	COG2814	Major facilitator Superfamily
GW13_RS03955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GW13_RS03960	COG0307	riboflavin synthase, alpha
GW13_RS04140	COG0789	Transcriptional regulator
GW13_RS04145	COG3272	Protein of unknown function (DUF1722)
GW13_RS04180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GW13_RS04190	COG2267	carboxylic ester hydrolase activity
GW13_RS04195	COG0531	amino acid
GW13_RS04225	COG1376	ErfK ybiS ycfS ynhG family protein
GW13_RS04240	COG0719	Fe-S assembly protein
GW13_RS04245	COG0396	ATPase activity
GW13_RS04250	COG0719	Fe-S assembly protein
GW13_RS04255	COG0316	Belongs to the HesB IscA family
GW13_RS04260	COG1823	symporter activity
GW13_RS04270	COG2050	protein possibly involved in aromatic compounds catabolism
GW13_RS04275	COG0277	FAD linked oxidase domain protein
GW13_RS04275	COG0247	lactate metabolic process
GW13_RS04280	COG0628	permease
GW13_RS04295	COG0738	Major facilitator superfamily
GW13_RS04300	COG2271	Major facilitator Superfamily
GW13_RS04315	COG4670	ketone body catabolic process
GW13_RS04320	COG1960	acyl-CoA dehydrogenase activity
GW13_RS04325	COG2207	Transcriptional regulator
GW13_RS04325	COG1917	Cupin 2, conserved barrel domain protein
GW13_RS04330	COG2086	electron transfer activity
GW13_RS04335	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GW13_RS04340	COG0644	oxidoreductase
GW13_RS04345	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GW13_RS04350	COG0318	PFAM AMP-dependent synthetase and ligase
GW13_RS04355	COG0574	Belongs to the PEP-utilizing enzyme family
GW13_RS04355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GW13_RS04370	COG4256	Hemin uptake protein
GW13_RS04385	COG0791	NLP P60 protein
GW13_RS04395	COG0386	Belongs to the glutathione peroxidase family
GW13_RS04460	COG3137	Salt-induced outer membrane protein
GW13_RS04465	COG1105	Belongs to the carbohydrate kinase PfkB family
GW13_RS04475	COG3001	Fructosamine kinase
GW13_RS04485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GW13_RS04490	COG1988	membrane-bound metal-dependent
GW13_RS04495	COG1823	symporter activity
GW13_RS04510	COG0753	catalase activity
GW13_RS04520	COG1486	melibiose metabolic process
GW13_RS04525	COG2169	Transcriptional regulator
GW13_RS04525	COG1917	Cupin 2, conserved barrel domain protein
GW13_RS04530	COG1447	Phosphotransferase system cellobiose-specific component IIA
GW13_RS04535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GW13_RS04540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GW13_RS04550	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GW13_RS04560	COG0322	excinuclease ABC activity
GW13_RS04565	COG3678	ATP-independent chaperone mediated protein folding
GW13_RS04595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GW13_RS04610	COG0494	nUDIX hydrolase
GW13_RS04625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GW13_RS04635	COG0778	Nitroreductase
GW13_RS04640	COG0616	signal peptide processing
GW13_RS04645	COG0252	asparaginase activity
GW13_RS04650	COG1335	isochorismatase
GW13_RS04655	COG3139	Protein of unknown function (DUF1315)
GW13_RS04680	COG0656	L-ascorbic acid biosynthetic process
GW13_RS04685	COG0641	radical SAM
GW13_RS04690	COG3713	MltA-interacting MipA family protein
GW13_RS04695	COG2766	serine protein kinase
GW13_RS04705	COG2199	diguanylate cyclase activity
GW13_RS04710	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GW13_RS04720	COG2207	Transcriptional regulator
GW13_RS04725	COG2807	transmembrane transport
GW13_RS04730	COG3189	MarR family transcriptional regulator
GW13_RS04740	COG3042	response to heat
GW13_RS04745	COG2261	transglycosylase associated protein
GW13_RS04765	COG3615	Tellurite resistance protein tehB
GW13_RS04780	COG1605	Chorismate mutase
GW13_RS04795	COG0789	Transcriptional regulator
GW13_RS04810	COG3443	Belongs to the bacterial solute-binding protein 9 family
GW13_RS04825	COG0668	transmembrane transport
GW13_RS04830	COG1124	(ABC) transporter
GW13_RS04860	COG3038	cytochrome b561
GW13_RS04870	COG0071	Belongs to the small heat shock protein (HSP20) family
GW13_RS04965	COG0538	isocitrate dehydrogenase activity
GW13_RS04970	COG2135	peptidase activity
GW13_RS04985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GW13_RS05030	COG0538	isocitrate dehydrogenase activity
GW13_RS05060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GW13_RS05075	COG2850	peptidyl-arginine hydroxylation
GW13_RS05110	COG1177	transmembrane transport
GW13_RS05130	COG4591	ABC-type transport system involved in lipoprotein release permease component
GW13_RS05135	COG1136	(ABC) transporter
GW13_RS05140	COG4591	ABC-type transport system involved in lipoprotein release permease component
GW13_RS05145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GW13_RS05150	COG1388	LysM domain
GW13_RS05150	COG1376	ErfK ybiS ycfS ynhG family protein
GW13_RS05160	COG1309	transcriptional regulator
GW13_RS05165	COG3134	Outer membrane lipoprotein
GW13_RS05170	COG1252	NADH dehydrogenase
GW13_RS05195	COG5633	Lipoprotein
GW13_RS05200	COG0537	adenosine 5'-monophosphoramidase activity
GW13_RS05205	COG4773	Receptor
GW13_RS05215	COG0084	hydrolase, TatD family'
GW13_RS05220	COG0470	DNA polymerase III
GW13_RS05230	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GW13_RS05235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GW13_RS05240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GW13_RS05285	COG0564	pseudouridine synthase activity
GW13_RS05295	COG1530	ribonuclease E activity
GW13_RS05390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GW13_RS05400	COG2999	glutathione oxidoreductase activity
GW13_RS05440	COG3038	cytochrome b561
GW13_RS05455	COG1560	Kdo2-lipid A biosynthetic process
GW13_RS05475	COG5645	(Lipo)protein
GW13_RS05480	COG2943	transferase activity, transferring hexosyl groups
GW13_RS05500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GW13_RS05560	COG3381	protein complex oligomerization
GW13_RS05640	COG0582	viral genome integration into host DNA
GW13_RS05650	COG0582	viral genome integration into host DNA
GW13_RS05770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GW13_RS05785	COG0534	Mate efflux family protein
GW13_RS05825	COG1122	ATPase activity
GW13_RS05955	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GW13_RS05970	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
GW13_RS05985	COG1454	alcohol dehydrogenase
GW13_RS05985	COG1012	belongs to the aldehyde dehydrogenase family
GW13_RS05990	COG4656	Part of a membrane complex involved in electron transport
GW13_RS06025	COG1289	transmembrane transporter activity
GW13_RS06075	COG2925	Exonuclease
GW13_RS06080	COG0531	amino acid
GW13_RS06085	COG0583	DNA-binding transcription factor activity
GW13_RS06090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GW13_RS06205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GW13_RS06220	COG2327	Polysaccharide pyruvyl transferase
GW13_RS06225	COG2244	polysaccharide biosynthetic process
GW13_RS06230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GW13_RS06245	COG0297	glycogen (starch) synthase activity
GW13_RS06255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GW13_RS06260	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GW13_RS06265	COG0110	maltose O-acetyltransferase activity
GW13_RS06270	COG1216	Glycosyl transferase, family 2
GW13_RS06280	COG0438	transferase activity, transferring glycosyl groups
GW13_RS06285	COG1045	serine acetyltransferase
GW13_RS06290	COG0463	Glycosyl transferase, family 2
GW13_RS06315	COG1253	flavin adenine dinucleotide binding
GW13_RS06320	COG2982	Protein involved in outer membrane biogenesis
GW13_RS06335	COG5001	Diguanylate cyclase
GW13_RS06335	COG5002	protein histidine kinase activity
GW13_RS06335	COG3447	MASE1 domain protein
GW13_RS06340	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GW13_RS06350	COG0443	Heat shock 70 kDa protein
GW13_RS06375	COG2205	protein histidine kinase activity
GW13_RS06380	COG0745	RESPONSE REGULATOR receiver
GW13_RS06405	COG0826	peptidase U32
GW13_RS06430	COG1830	Aldolase
GW13_RS06435	COG2211	Major facilitator Superfamily
GW13_RS06440	COG1397	ADP-ribosylglycohydrolase
GW13_RS06445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GW13_RS06450	COG2188	Transcriptional regulator
GW13_RS06465	COG5455	response to cobalt ion
GW13_RS06475	COG3188	usher protein
GW13_RS06480	COG3121	Chaperone
GW13_RS06505	COG4808	Protein conserved in bacteria
GW13_RS06515	COG4807	Protein conserved in bacteria
GW13_RS06525	COG3275	phosphorelay sensor kinase activity
GW13_RS06540	COG1174	glycine betaine transport
GW13_RS06545	COG1125	glycine betaine transport
GW13_RS06550	COG1174	glycine betaine transport
GW13_RS06555	COG1732	Glycine betaine
GW13_RS06565	COG0277	FAD linked oxidase domain protein
GW13_RS06570	COG1686	Belongs to the peptidase S11 family
GW13_RS06585	COG0586	Pfam SNARE associated Golgi protein
GW13_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
GW13_RS06595	COG1538	Outer membrane efflux protein
GW13_RS06610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GW13_RS06615	COG0625	glutathione transferase activity
GW13_RS06630	COG2271	Major facilitator Superfamily
GW13_RS06645	COG1346	cytolysis
GW13_RS06655	COG2949	membrane
GW13_RS06695	COG2311	Membrane
GW13_RS06720	COG1760	l-serine dehydratase
GW13_RS06725	COG0560	Phosphoserine phosphatase
GW13_RS06730	COG2271	Major facilitator Superfamily
GW13_RS06735	COG4771	TonB-dependent receptor
GW13_RS06745	COG0833	amino acid
GW13_RS06750	COG0583	DNA-binding transcription factor activity
GW13_RS06755	COG2855	membrane
GW13_RS06765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GW13_RS06765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GW13_RS06765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GW13_RS06770	COG1105	Belongs to the carbohydrate kinase PfkB family
GW13_RS06800	COG0523	cobalamin synthesis protein
GW13_RS06805	COG0671	phosphoesterase, PA-phosphatase related
GW13_RS06815	COG0791	NLP P60 protein
GW13_RS06825	COG2200	EAL domain
GW13_RS06830	COG4166	transmembrane transport
GW13_RS06835	COG4174	ABC transporter (Permease)
GW13_RS06840	COG4239	(ABC) transporter, permease
GW13_RS06845	COG4172	Belongs to the ABC transporter superfamily
GW13_RS06860	COG2814	Major facilitator Superfamily
GW13_RS06870	COG1061	Type III restriction enzyme res subunit
GW13_RS06920	COG2197	response regulator
GW13_RS06925	COG4235	cytochrome complex assembly
GW13_RS06925	COG3088	subunit of a heme lyase
GW13_RS06935	COG1138	Cytochrome C-type biogenesis protein
GW13_RS06945	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GW13_RS06950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GW13_RS06955	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GW13_RS06965	COG3005	denitrification pathway
GW13_RS06970	COG3043	anaerobic respiration
GW13_RS06975	COG0348	domain, Protein
GW13_RS06980	COG0437	4 iron, 4 sulfur cluster binding
GW13_RS06990	COG3062	negative regulation of establishment of protein localization
GW13_RS06995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GW13_RS06995	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GW13_RS07005	COG4615	Cyclic peptide transporter
GW13_RS07035	COG2198	Histidine kinase
GW13_RS07035	COG0642	Histidine kinase
GW13_RS07060	COG4948	Mandelate Racemase Muconate Lactonizing
GW13_RS07090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GW13_RS07095	COG2814	Major facilitator Superfamily
GW13_RS07100	COG0583	DNA-binding transcription factor activity
GW13_RS07105	COG0584	glycerophosphoryl diester phosphodiesterase
GW13_RS07110	COG2271	Major facilitator Superfamily
GW13_RS07115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GW13_RS07125	COG0247	lactate metabolic process
GW13_RS07135	COG5160	protein modification by small protein removal
GW13_RS07225	COG1169	isochorismate synthase
GW13_RS07230	COG4575	ribosome binding
GW13_RS07235	COG2153	protein acetylation
GW13_RS07245	COG0835	chemotaxis
GW13_RS07245	COG0784	Response regulator, receiver
GW13_RS07255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GW13_RS07260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GW13_RS07270	COG0839	Belongs to the complex I subunit 6 family
GW13_RS07315	COG0583	DNA-binding transcription factor activity
GW13_RS07325	COG0436	Aminotransferase
GW13_RS07335	COG0471	metal ion transport
GW13_RS07335	COG0490	domain, Protein
GW13_RS07340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GW13_RS07365	COG1288	antiporter activity
GW13_RS07370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GW13_RS07375	COG3959	Transketolase, thiamine diphosphate binding domain
GW13_RS07380	COG3037	sugar-specific permease SgaT UlaA
GW13_RS07390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS07400	COG1609	Transcriptional regulator
GW13_RS07410	COG0622	Phosphoesterase
GW13_RS07415	COG0625	glutathione transferase activity
GW13_RS07420	COG0625	glutathione transferase activity
GW13_RS07425	COG1090	epimerase
GW13_RS07465	COG0833	amino acid
GW13_RS07470	COG3457	Alanine racemase
GW13_RS07475	COG0531	amino acid
GW13_RS07485	COG3829	transcription factor binding
GW13_RS07490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GW13_RS07495	COG1286	toxin biosynthetic process
GW13_RS07500	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GW13_RS07505	COG0285	dihydrofolate synthase activity
GW13_RS07515	COG0586	Pfam SNARE associated Golgi protein
GW13_RS07525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GW13_RS07570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GW13_RS07585	COG3101	peptidyl-lysine hydroxylation
GW13_RS07590	COG0730	response to heat
GW13_RS07615	COG2062	phosphohistidine phosphatase, SixA
GW13_RS07630	COG3691	Protein conserved in bacteria
GW13_RS07645	COG2116	formate transmembrane transporter activity
GW13_RS07690	COG1560	Kdo2-lipid A biosynthetic process
GW13_RS07695	COG0436	Aminotransferase
GW13_RS07710	COG3961	Belongs to the TPP enzyme family
GW13_RS07715	COG0667	Aldo Keto reductase
GW13_RS07730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GW13_RS07735	COG2199	diguanylate cyclase activity
GW13_RS07735	COG2200	EAL domain
GW13_RS07750	COG3415	Transposase
GW13_RS07755	COG3415	Transposase
GW13_RS07785	COG0583	DNA-binding transcription factor activity
GW13_RS07795	COG2211	Major facilitator Superfamily
GW13_RS07800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GW13_RS07810	COG0583	DNA-binding transcription factor activity
GW13_RS07815	COG0385	Bile acid
GW13_RS07820	COG3530	Putative quorum-sensing-regulated virulence factor
GW13_RS07850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS07895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GW13_RS07900	COG4208	sulfate ABC transporter
GW13_RS07920	COG2837	iron assimilation
GW13_RS08050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GW13_RS08060	COG5342	invasion associated locus B
GW13_RS08075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GW13_RS08075	COG0493	'glutamate synthase
GW13_RS08080	COG3850	Histidine kinase
GW13_RS08085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GW13_RS08090	COG1393	Belongs to the ArsC family
GW13_RS08110	COG2321	neutral zinc metallopeptidase
GW13_RS08125	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GW13_RS08135	COG2716	regulation of RNA biosynthetic process
GW13_RS08140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GW13_RS08145	COG1929	Belongs to the glycerate kinase type-1 family
GW13_RS08150	COG2610	gluconate transmembrane transporter activity
GW13_RS08155	COG3835	regulator
GW13_RS08160	COG0628	permease
GW13_RS08170	COG1393	Belongs to the ArsC family
GW13_RS08180	COG2233	PERMEase
GW13_RS08200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GW13_RS08215	COG2200	EAL domain
GW13_RS08225	COG3133	Outer membrane lipoprotein
GW13_RS08250	COG0516	GMP reductase activity
GW13_RS08250	COG0517	IMP dehydrogenase activity
GW13_RS08290	COG1645	bacterial-type flagellum-dependent swarming motility
GW13_RS08305	COG2976	Protein conserved in bacteria
GW13_RS08350	COG0437	4 iron, 4 sulfur cluster binding
GW13_RS08355	COG0243	molybdopterin cofactor binding
GW13_RS08360	COG4953	penicillin-binding protein 1C
GW13_RS08365	COG2373	Large extracellular alpha-helical protein
GW13_RS08370	COG2897	thiosulfate sulfurtransferase activity
GW13_RS08400	COG2975	iron-sulfur cluster assembly
GW13_RS08405	COG0633	Ferredoxin
GW13_RS08425	COG0822	iron-sulfur transferase activity
GW13_RS08470	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GW13_RS08480	COG3711	transcriptional antiterminator
GW13_RS08485	COG2814	Major facilitator Superfamily
GW13_RS08500	COG3710	Transcriptional regulator
GW13_RS08505	COG0531	amino acid
GW13_RS08515	COG3104	oligopeptide transport
GW13_RS08520	COG0347	Belongs to the P(II) protein family
GW13_RS08525	COG2204	response regulator
GW13_RS08530	COG3170	Tfp pilus assembly protein FimV
GW13_RS08535	COG2205	protein histidine kinase activity
GW13_RS08560	COG0560	Phosphoserine phosphatase
GW13_RS08565	COG1263	PTS System
GW13_RS08565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GW13_RS08575	COG1737	Transcriptional regulator
GW13_RS08580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GW13_RS08585	COG2223	nitrite transmembrane transporter activity
GW13_RS08590	COG0583	DNA-binding transcription factor activity
GW13_RS08595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GW13_RS08645	COG3086	response to oxidative stress
GW13_RS08680	COG0513	Belongs to the DEAD box helicase family
GW13_RS08685	COG0583	DNA-binding transcription factor activity
GW13_RS08705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GW13_RS08710	COG3118	belongs to the thioredoxin family
GW13_RS08715	COG3148	PFAM DTW domain containing protein
GW13_RS08725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GW13_RS08730	COG5544	Lipoprotein
GW13_RS08735	COG0477	Major facilitator Superfamily
GW13_RS08770	COG0542	response to heat
GW13_RS08785	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GW13_RS08790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GW13_RS08795	COG1605	Chorismate mutase
GW13_RS08795	COG0077	Prephenate dehydratase
GW13_RS08805	COG1605	Chorismate mutase
GW13_RS08805	COG0287	Prephenate dehydrogenase
GW13_RS08820	COG2199	diguanylate cyclase activity
GW13_RS08845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GW13_RS08850	COG4137	Cytochrome C assembly protein
GW13_RS08855	COG4536	flavin adenine dinucleotide binding
GW13_RS08880	COG0497	DNA recombination
GW13_RS08895	COG2867	negative regulation of translational initiation
GW13_RS08920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GW13_RS08960	COG2826	transposase and inactivated derivatives, IS30 family
GW13_RS08970	COG3813	Protein conserved in bacteria
GW13_RS08990	COG1132	(ABC) transporter
GW13_RS09000	COG2819	hydrolase of the alpha beta superfamily
GW13_RS09020	COG2990	Protein conserved in bacteria
GW13_RS09035	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GW13_RS09070	COG0579	oxidoreductase
GW13_RS09075	COG1012	belongs to the aldehyde dehydrogenase family
GW13_RS09080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GW13_RS09085	COG1113	amino acid transport
GW13_RS09090	COG1802	Transcriptional regulator
GW13_RS09095	COG1652	LysM domain
GW13_RS09100	COG0401	homolog of Blt101
GW13_RS09105	COG0640	Transcriptional regulator
GW13_RS09110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GW13_RS09135	COG4575	ribosome binding
GW13_RS09145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GW13_RS09195	COG2814	Major facilitator Superfamily
GW13_RS09200	COG1846	Transcriptional regulator
GW13_RS09205	COG1566	PFAM secretion protein HlyD family protein
GW13_RS09210	COG2814	Major facilitator Superfamily
GW13_RS09230	COG1238	metal cluster binding
GW13_RS09235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GW13_RS09270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GW13_RS09295	COG1546	Belongs to the CinA family
GW13_RS09305	COG2951	lytic endotransglycosylase activity
GW13_RS09310	COG3730	PTS system glucitol sorbitol-specific
GW13_RS09315	COG3732	PTS system glucitol sorbitol-specific
GW13_RS09325	COG1028	Short-chain dehydrogenase reductase Sdr
GW13_RS09330	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS09335	COG1349	DNA-binding transcription factor activity
GW13_RS09340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GW13_RS09340	COG0517	IMP dehydrogenase activity
GW13_RS09360	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GW13_RS09365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GW13_RS09375	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GW13_RS09385	COG3260	NADH ubiquinone oxidoreductase 20
GW13_RS09390	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GW13_RS09395	COG3261	NADH dehydrogenase
GW13_RS09395	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GW13_RS09400	COG0650	Formate hydrogenlyase subunit 4
GW13_RS09405	COG0651	ATP synthesis coupled electron transport
GW13_RS09410	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GW13_RS09430	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GW13_RS09435	COG0298	carbon dioxide binding
GW13_RS09440	COG0409	Hydrogenase expression formation protein
GW13_RS09445	COG0309	Hydrogenase expression formation protein (HypE)
GW13_RS09465	COG1121	(ABC) transporter
GW13_RS09470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GW13_RS09475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GW13_RS09565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GW13_RS09655	COG2207	Transcriptional regulator
GW13_RS09725	COG0477	Major facilitator Superfamily
GW13_RS09735	COG2610	gluconate transmembrane transporter activity
GW13_RS09740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GW13_RS09745	COG3622	Belongs to the hyi family
GW13_RS09750	COG0235	Class ii aldolase
GW13_RS09760	COG2084	Dehydrogenase
GW13_RS09765	COG1349	DNA-binding transcription factor activity
GW13_RS09775	COG0163	prenyltransferase activity
GW13_RS09780	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GW13_RS09860	COG2234	aminopeptidase activity
GW13_RS09865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GW13_RS09870	COG1518	maintenance of DNA repeat elements
GW13_RS09885	COG1857	crispr-associated protein
GW13_RS09900	COG1203	CRISPR-associated helicase, Cas3
GW13_RS09930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GW13_RS09940	COG0720	synthase
GW13_RS09945	COG0321	lipoyl(octanoyl) transferase activity
GW13_RS09945	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GW13_RS09950	COG0602	queuosine metabolic process
GW13_RS09965	COG3956	TIGRFAM MazG family protein
GW13_RS09970	COG3539	Fimbrial protein
GW13_RS09975	COG3188	usher protein
GW13_RS09980	COG3121	Chaperone
GW13_RS09985	COG3539	Fimbrial protein
GW13_RS10015	COG3609	addiction module antidote protein, CC2985 family
GW13_RS10020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GW13_RS10030	COG3437	response regulator, receiver
GW13_RS10030	COG4999	Histidine kinase
GW13_RS10030	COG2205	protein histidine kinase activity
GW13_RS10030	COG3850	Histidine kinase
GW13_RS10035	COG1929	Belongs to the glycerate kinase type-1 family
GW13_RS10040	COG4948	Mandelate Racemase Muconate Lactonizing
GW13_RS10045	COG4948	Mandelate Racemase Muconate Lactonizing
GW13_RS10050	COG2271	Major facilitator Superfamily
GW13_RS10060	COG0716	FMN binding
GW13_RS10070	COG3098	single-species biofilm formation
GW13_RS10090	COG1611	Belongs to the LOG family
GW13_RS10095	COG0814	amino acid
GW13_RS10100	COG1760	l-serine dehydratase
GW13_RS10115	COG1454	alcohol dehydrogenase
GW13_RS10120	COG0235	Class ii aldolase
GW13_RS10125	COG0738	Major facilitator superfamily
GW13_RS10145	COG1349	DNA-binding transcription factor activity
GW13_RS10155	COG2363	Small membrane protein
GW13_RS10160	COG0583	DNA-binding transcription factor activity
GW13_RS10170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GW13_RS10175	COG2166	iron-sulfur cluster assembly
GW13_RS10180	COG2962	Rard protein
GW13_RS10185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GW13_RS10190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GW13_RS10205	COG0860	N-Acetylmuramoyl-L-alanine amidase
GW13_RS10215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GW13_RS10220	COG1074	ATP-dependent DNA helicase activity
GW13_RS10230	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GW13_RS10235	COG4967	type IV pilus modification protein PilV
GW13_RS10245	COG4795	General secretion pathway protein
GW13_RS10250	COG2165	general secretion pathway protein
GW13_RS10285	COG0861	Integral membrane protein TerC family
GW13_RS10295	COG0667	Aldo Keto reductase
GW13_RS10315	COG1609	Transcriptional regulator
GW13_RS10325	COG0583	DNA-binding transcription factor activity
GW13_RS10330	COG1794	racemase activity, acting on amino acids and derivatives
GW13_RS10335	COG2814	Major facilitator Superfamily
GW13_RS10340	COG1028	Short-chain dehydrogenase reductase Sdr
GW13_RS10355	COG0183	Belongs to the thiolase family
GW13_RS10370	COG0814	amino acid
GW13_RS10405	COG3188	usher protein
GW13_RS10450	COG4942	peptidase
GW13_RS10520	COG1272	protein, Hemolysin III
GW13_RS10530	COG2723	6-phospho-beta-galactosidase activity
GW13_RS10565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GW13_RS10570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GW13_RS10575	COG0006	proline dipeptidase activity
GW13_RS10600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GW13_RS10605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GW13_RS10625	COG2968	Membrane
GW13_RS10635	COG0668	transmembrane transport
GW13_RS10640	COG0191	fructose-bisphosphate aldolase activity
GW13_RS10675	COG1122	ATPase activity
GW13_RS10680	COG1122	ATPase activity
GW13_RS10685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GW13_RS10690	COG0501	Belongs to the peptidase M48B family
GW13_RS10700	COG1166	arginine decarboxylase activity
GW13_RS10720	COG2814	Major facilitator Superfamily
GW13_RS10730	COG2356	endonuclease I
GW13_RS10735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GW13_RS10760	COG2805	Type II/IV secretion system protein
GW13_RS10765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GW13_RS10770	COG0762	integral membrane protein
GW13_RS10785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GW13_RS10795	COG0252	asparaginase activity
GW13_RS10805	COG3171	Protein conserved in bacteria
GW13_RS10835	COG2211	Major facilitator Superfamily
GW13_RS10840	COG1982	Orn Lys Arg decarboxylase major
GW13_RS10850	COG1811	Na channel or pump
GW13_RS10870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GW13_RS10880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GW13_RS10910	COG0531	amino acid
GW13_RS10920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GW13_RS10925	COG1012	belongs to the aldehyde dehydrogenase family
GW13_RS10950	COG2271	Major facilitator Superfamily
GW13_RS10960	COG0246	Mannitol dehydrogenase
GW13_RS10975	COG0754	glutathionylspermidine amidase activity
GW13_RS10980	COG0625	glutathione transferase activity
GW13_RS10990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GW13_RS10995	COG0298	carbon dioxide binding
GW13_RS11005	COG1773	rubredoxin
GW13_RS11010	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GW13_RS11015	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GW13_RS11020	COG5557	Pfam Polysulphide reductase, NrfD
GW13_RS11025	COG0437	4 iron, 4 sulfur cluster binding
GW13_RS11030	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GW13_RS11045	COG0840	transmembrane signaling receptor activity
GW13_RS11070	COG1028	Short-chain dehydrogenase reductase Sdr
GW13_RS11075	COG0848	biopolymer transport protein
GW13_RS11095	COG2207	Transcriptional regulator
GW13_RS11100	COG1979	alcohol dehydrogenase
GW13_RS11110	COG0471	metal ion transport
GW13_RS11140	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GW13_RS11145	COG3111	PFAM Bacterial OB fold (BOF) protein
GW13_RS11155	COG0642	Histidine kinase
GW13_RS11160	COG2249	NAD(P)H dehydrogenase (quinone) activity
GW13_RS11165	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GW13_RS11175	COG3150	esterase
GW13_RS11180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GW13_RS11185	COG3151	Protein conserved in bacteria
GW13_RS11190	COG0494	nUDIX hydrolase
GW13_RS11210	COG0754	glutathionylspermidine amidase activity
GW13_RS11215	COG3384	dioxygenase
GW13_RS11260	COG1585	Membrane protein implicated in regulation of membrane protease activity
GW13_RS11265	COG2268	Band 7 protein
GW13_RS11285	COG3025	triphosphatase activity
GW13_RS11290	COG4991	sh3 domain protein
GW13_RS11305	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GW13_RS11315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GW13_RS11325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GW13_RS11350	COG2375	cellular response to nickel ion
GW13_RS11355	COG1695	Transcriptional regulator
GW13_RS11360	COG0840	transmembrane signaling receptor activity
GW13_RS11365	COG0840	transmembrane signaling receptor activity
GW13_RS11380	COG0446	pyridine nucleotide-disulphide oxidoreductase
GW13_RS11380	COG1902	pentaerythritol trinitrate reductase activity
GW13_RS11390	COG1451	nucleotide metabolic process
GW13_RS11395	COG2949	membrane
GW13_RS11400	COG0673	inositol 2-dehydrogenase activity
GW13_RS11415	COG0586	Pfam SNARE associated Golgi protein
GW13_RS11425	COG1422	Protein of unknown function (DUF1090)
GW13_RS11430	COG4575	ribosome binding
GW13_RS11435	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GW13_RS11445	COG2259	Doxx family
GW13_RS11450	COG0435	Glutathione S-transferase
GW13_RS11455	COG3152	Membrane
GW13_RS11460	COG0583	DNA-binding transcription factor activity
GW13_RS11465	COG1741	Belongs to the pirin family
GW13_RS11480	COG0814	amino acid
GW13_RS11485	COG1760	l-serine dehydratase
GW13_RS11490	COG1882	Formate acetyltransferase
GW13_RS11495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GW13_RS11510	COG0583	DNA-binding transcription factor activity
GW13_RS11535	COG1929	Belongs to the glycerate kinase type-1 family
GW13_RS11540	COG2084	Dehydrogenase
GW13_RS11550	COG2721	sulfolactate sulfo-lyase activity
GW13_RS11555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GW13_RS11560	COG1349	DNA-binding transcription factor activity
GW13_RS11575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GW13_RS11575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GW13_RS11575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS11590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS11595	COG3414	Phosphotransferase system galactitol-specific IIB component
GW13_RS11600	COG3775	system Galactitol-specific IIC component
GW13_RS11605	COG1063	alcohol dehydrogenase
GW13_RS11615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GW13_RS11620	COG3107	peptidoglycan biosynthetic process
GW13_RS11635	COG2823	Periplasmic or secreted lipoprotein
GW13_RS11640	COG0702	epimerase
GW13_RS11645	COG0693	protein deglycase activity
GW13_RS11660	COG3153	acetyltransferase
GW13_RS11665	COG3154	lipid carrier protein
GW13_RS11670	COG0826	peptidase U32
GW13_RS11675	COG0826	peptidase U32
GW13_RS11680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GW13_RS11685	COG0814	amino acid
GW13_RS11690	COG0513	Belongs to the DEAD box helicase family
GW13_RS11765	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GW13_RS11775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GW13_RS11795	COG1534	Rna-binding protein
GW13_RS11805	COG2027	D-alanyl-D-alanine carboxypeptidase
GW13_RS11830	COG0697	spore germination
GW13_RS11845	COG0142	geranyltranstransferase activity
GW13_RS11850	COG3423	Transcriptional regulator
GW13_RS11860	COG5007	Belongs to the BolA IbaG family
GW13_RS11865	COG3113	response to antibiotic
GW13_RS11870	COG2854	intermembrane phospholipid transfer
GW13_RS11875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GW13_RS11880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GW13_RS11885	COG1127	ABC transporter
GW13_RS11890	COG0530	calcium, potassium:sodium antiporter activity
GW13_RS11900	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GW13_RS11905	COG3117	lipopolysaccharide transmembrane transporter activity
GW13_RS11910	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GW13_RS11915	COG1137	ATPase activity
GW13_RS11940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS11950	COG0515	serine threonine protein kinase
GW13_RS11955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GW13_RS11960	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GW13_RS11965	COG2198	Histidine kinase
GW13_RS11965	COG0784	Response regulator, receiver
GW13_RS11965	COG5002	protein histidine kinase activity
GW13_RS11970	COG1242	4 iron, 4 sulfur cluster binding
GW13_RS11985	COG0067	glutamate synthase
GW13_RS11985	COG0069	glutamate synthase activity
GW13_RS11985	COG0070	glutamate synthase
GW13_RS11990	COG0493	'glutamate synthase
GW13_RS11995	COG4804	nuclease activity
GW13_RS12000	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GW13_RS12005	COG0402	S-adenosylhomocysteine deaminase activity
GW13_RS12010	COG2731	YhcH YjgK YiaL family protein
GW13_RS12015	COG1940	carbohydrate kinase activity
GW13_RS12040	COG2969	positive regulation of protein catabolic process
GW13_RS12045	COG0625	glutathione transferase activity
GW13_RS12065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GW13_RS12070	COG3105	Protein conserved in bacteria
GW13_RS12075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GW13_RS12090	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GW13_RS12095	COG5016	pyruvate
GW13_RS12095	COG0511	ligase activity, forming carbon-carbon bonds
GW13_RS12105	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GW13_RS12110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GW13_RS12115	COG0471	metal ion transport
GW13_RS12125	COG2188	Transcriptional regulator
GW13_RS12150	COG2732	(Barnase) inhibitor
GW13_RS12170	COG0583	DNA-binding transcription factor activity
GW13_RS12175	COG0312	modulator of DNA gyrase
GW13_RS12180	COG3164	Protein of unknown function
GW13_RS12195	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GW13_RS12200	COG1792	Involved in formation and maintenance of cell shape
GW13_RS12205	COG1077	Cell shape determining protein MreB Mrl
GW13_RS12220	COG2199	diguanylate cyclase activity
GW13_RS12220	COG2200	EAL domain
GW13_RS12225	COG0604	alcohol dehydrogenase
GW13_RS12240	COG0511	ligase activity, forming carbon-carbon bonds
GW13_RS12245	COG0439	Biotin carboxylase
GW13_RS12250	COG3924	membrane
GW13_RS12255	COG4145	pantothenate transmembrane transporter activity
GW13_RS12275	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GW13_RS12290	COG1309	transcriptional regulator
GW13_RS12295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GW13_RS12300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GW13_RS12350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GW13_RS12370	COG0551	DNA topoisomerase type I activity
GW13_RS12380	COG0758	DNA mediated transformation
GW13_RS12410	COG3036	rescue of stalled ribosome
GW13_RS12415	COG0789	Transcriptional regulator
GW13_RS12455	COG0201	protein transport
GW13_RS12535	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GW13_RS12560	COG0051	transcription antitermination factor activity, RNA binding
GW13_RS12630	COG2964	Protein conserved in bacteria
GW13_RS12635	COG0545	Peptidyl-prolyl cis-trans isomerase
GW13_RS12645	COG1047	Peptidyl-prolyl cis-trans
GW13_RS12650	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GW13_RS12665	COG0488	(ABC) transporter
GW13_RS12680	COG0429	hydrolase of the alpha beta-hydrolase fold
GW13_RS12690	COG3954	Phosphoribulokinase
GW13_RS12695	COG1765	OsmC-like protein
GW13_RS12705	COG1289	transmembrane transporter activity
GW13_RS12740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GW13_RS12780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GW13_RS12785	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GW13_RS12790	COG3266	domain, Protein
GW13_RS12810	COG4796	Type ii and iii secretion system protein
GW13_RS12825	COG3166	PFAM Fimbrial assembly family protein
GW13_RS12830	COG4972	Pilus assembly protein
GW13_RS12835	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GW13_RS12840	COG0494	nUDIX hydrolase
GW13_RS12850	COG1011	Hydrolase
GW13_RS12855	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GW13_RS12865	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GW13_RS12885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GW13_RS12890	COG2183	response to ionizing radiation
GW13_RS12900	COG1918	ferrous iron import across plasma membrane
GW13_RS12915	COG5464	transposase or invertase
GW13_RS12935	COG2610	gluconate transmembrane transporter activity
GW13_RS12940	COG1640	4-alpha-glucanotransferase
GW13_RS12945	COG0058	SHG alpha-glucan phosphorylase activity
GW13_RS12955	COG1349	DNA-binding transcription factor activity
GW13_RS12960	COG0705	Rhomboid family
GW13_RS12970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GW13_RS12975	COG0058	SHG alpha-glucan phosphorylase activity
GW13_RS12995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GW13_RS13005	COG2610	gluconate transmembrane transporter activity
GW13_RS13010	COG3265	gluconokinase activity
GW13_RS13015	COG1609	Transcriptional regulator
GW13_RS13020	COG1741	Belongs to the pirin family
GW13_RS13025	COG0673	inositol 2-dehydrogenase activity
GW13_RS13035	COG1247	-acetyltransferase
GW13_RS13040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GW13_RS13055	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GW13_RS13060	COG0405	Gamma-glutamyltransferase
GW13_RS13070	COG0584	glycerophosphoryl diester phosphodiesterase
GW13_RS13140	COG2177	Part of the ABC transporter FtsEX involved in
GW13_RS13145	COG2884	Cell division ATP-binding protein ftsE
GW13_RS13150	COG0552	protein localization to endoplasmic reticulum
GW13_RS13155	COG0742	ribosomal rna small subunit methyltransferase
GW13_RS13160	COG3776	membrane
GW13_RS13170	COG3714	YhhN family
GW13_RS13190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GW13_RS13205	COG0628	permease
GW13_RS13210	COG2091	lysine biosynthetic process via aminoadipic acid
GW13_RS13220	COG0842	Transport permease protein
GW13_RS13225	COG0842	Transport permease protein
GW13_RS13225	COG1129	ABC transporter
GW13_RS13230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GW13_RS13235	COG2081	HI0933 family
GW13_RS13240	COG0306	phosphate transporter
GW13_RS13270	COG0671	phosphoesterase, PA-phosphatase related
GW13_RS13275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GW13_RS13280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GW13_RS13300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GW13_RS13305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GW13_RS13310	COG2222	sugar isomerase
GW13_RS13315	COG2188	Transcriptional regulator
GW13_RS13335	COG2197	response regulator
GW13_RS13340	COG0583	DNA-binding transcription factor activity
GW13_RS13345	COG1295	ribonuclease BN
GW13_RS13350	COG0477	Major facilitator Superfamily
GW13_RS13355	COG2982	Protein involved in outer membrane biogenesis
GW13_RS13360	COG2200	EAL domain
GW13_RS13365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GW13_RS13380	COG2199	diguanylate cyclase activity
GW13_RS13380	COG2200	EAL domain
GW13_RS13400	COG1215	transferase activity, transferring glycosyl groups
GW13_RS13445	COG2873	o-acetylhomoserine
GW13_RS13450	COG0814	amino acid
GW13_RS13455	COG4608	Belongs to the ABC transporter superfamily
GW13_RS13460	COG0444	Belongs to the ABC transporter superfamily
GW13_RS13465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GW13_RS13470	COG0601	transmembrane transport
GW13_RS13480	COG0747	negative chemotaxis
GW13_RS13525	COG5571	outer membrane autotransporter
GW13_RS13530	COG2818	Glycosylase
GW13_RS13535	COG0456	acetyltransferase
GW13_RS13540	COG0243	molybdopterin cofactor binding
GW13_RS13545	COG2885	chlorophyll binding
GW13_RS13550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GW13_RS13560	COG2944	sequence-specific DNA binding
GW13_RS13565	COG1278	Cold shock
GW13_RS13595	COG3274	enterobacterial common antigen metabolic process
GW13_RS13600	COG4682	membrane
GW13_RS13605	COG1070	Carbohydrate kinase
GW13_RS13620	COG1609	Transcriptional regulator
GW13_RS13620	COG2207	Transcriptional regulator
GW13_RS13625	COG2992	FlgJ-related protein
GW13_RS13630	COG0366	Alpha amylase catalytic
GW13_RS13635	COG3977	Valine--pyruvate aminotransferase
GW13_RS13640	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GW13_RS13645	COG0235	Class ii aldolase
GW13_RS13665	COG1012	belongs to the aldehyde dehydrogenase family
GW13_RS13670	COG1940	carbohydrate kinase activity
GW13_RS13675	COG3276	selenocysteine insertion sequence binding
GW13_RS13685	COG0625	glutathione transferase activity
GW13_RS13690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS13690	COG2213	PTS system mannitol-specific
GW13_RS13700	COG3722	fumarate hydratase activity
GW13_RS13735	COG2186	Transcriptional regulator
GW13_RS13745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GW13_RS13750	COG1609	Transcriptional regulator
GW13_RS13765	COG2271	Major facilitator Superfamily
GW13_RS13785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GW13_RS13790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GW13_RS13800	COG4942	peptidase
GW13_RS13805	COG2861	carbohydrate metabolic process
GW13_RS13810	COG1216	Glycosyl transferase, family 2
GW13_RS13885	COG0438	transferase activity, transferring glycosyl groups
GW13_RS13890	COG0859	PFAM glycosyl transferase family 9
GW13_RS13895	COG1519	Transferase
GW13_RS13925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GW13_RS13955	COG1561	YicC-like family, N-terminal region
GW13_RS13960	COG0583	DNA-binding transcription factor activity
GW13_RS13970	COG2860	membrane
GW13_RS13990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GW13_RS13995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GW13_RS14000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GW13_RS14005	COG0786	glutamate:sodium symporter activity
GW13_RS14010	COG2233	PERMEase
GW13_RS14015	COG2982	Protein involved in outer membrane biogenesis
GW13_RS14020	COG1501	Belongs to the glycosyl hydrolase 31 family
GW13_RS14025	COG2211	Major facilitator Superfamily
GW13_RS14060	COG2963	transposase activity
GW13_RS14065	COG2771	luxR family
GW13_RS14080	COG3710	Transcriptional regulator
GW13_RS14085	COG1335	isochorismatase
GW13_RS14100	COG1285	pathogenesis
GW13_RS14110	COG5464	transposase or invertase
GW13_RS14125	COG3716	PTS system mannose fructose sorbose family IID component
GW13_RS14130	COG3715	PTS system
GW13_RS14140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GW13_RS14140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS14165	COG2723	6-phospho-beta-galactosidase activity
GW13_RS14200	COG3775	system Galactitol-specific IIC component
GW13_RS14205	COG3414	Phosphotransferase system galactitol-specific IIB component
GW13_RS14210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS14210	COG3711	transcriptional antiterminator
GW13_RS14215	COG2188	Transcriptional regulator
GW13_RS14265	COG0738	Major facilitator superfamily
GW13_RS14275	COG1349	DNA-binding transcription factor activity
GW13_RS14280	COG0440	acetolactate synthase activity
GW13_RS14285	COG0028	Belongs to the TPP enzyme family
GW13_RS14305	COG2814	Major facilitator Superfamily
GW13_RS14315	COG0583	DNA-binding transcription factor activity
GW13_RS14320	COG2610	gluconate transmembrane transporter activity
GW13_RS14330	COG0641	radical SAM
GW13_RS14340	COG2149	membrane
GW13_RS14350	COG0071	Belongs to the small heat shock protein (HSP20) family
GW13_RS14360	COG5645	(Lipo)protein
GW13_RS14365	COG0823	Involved in the tonB-independent uptake of proteins
GW13_RS14390	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GW13_RS14395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GW13_RS14400	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GW13_RS14410	COG1858	cytochrome C peroxidase
GW13_RS14425	COG3005	denitrification pathway
GW13_RS14430	COG0745	RESPONSE REGULATOR receiver
GW13_RS14435	COG1879	ABC-type sugar transport system periplasmic component
GW13_RS14440	COG0784	Response regulator, receiver
GW13_RS14440	COG2205	protein histidine kinase activity
GW13_RS14440	COG2198	Histidine kinase
GW13_RS14445	COG2271	Major facilitator Superfamily
GW13_RS14455	COG0800	Aldolase
GW13_RS14460	COG3734	2-keto-3-deoxy-galactonokinase
GW13_RS14465	COG2186	Transcriptional regulator
GW13_RS14470	COG0561	phosphatase activity
GW13_RS14475	COG2271	Major facilitator Superfamily
GW13_RS14480	COG4948	Mandelate Racemase Muconate Lactonizing
GW13_RS14545	COG2091	lysine biosynthetic process via aminoadipic acid
GW13_RS14550	COG0431	NADPH-dependent FMN reductase
GW13_RS14555	COG2252	PERMEase
GW13_RS14560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GW13_RS14565	COG0704	Plays a role in the regulation of phosphate uptake
GW13_RS14575	COG0581	inorganic phosphate transmembrane transporter activity
GW13_RS14580	COG0573	inorganic phosphate transmembrane transporter activity
GW13_RS14585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GW13_RS14590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GW13_RS14590	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GW13_RS14590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GW13_RS14595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GW13_RS14600	COG4533	DNA binding
GW13_RS14665	COG3312	ion transport
GW13_RS14680	COG0716	FMN binding
GW13_RS14685	COG1522	sequence-specific DNA binding
GW13_RS14720	COG1172	Belongs to the binding-protein-dependent transport system permease family
GW13_RS14730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GW13_RS14735	COG1609	Transcriptional regulator
GW13_RS14740	COG0477	Major facilitator Superfamily
GW13_RS14745	COG2186	Transcriptional regulator
GW13_RS14805	COG3978	acetolactate synthase activity
GW13_RS14885	COG3118	belongs to the thioredoxin family
GW13_RS14900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GW13_RS14915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GW13_RS14920	COG1088	dTDP-glucose 4,6-dehydratase activity
GW13_RS14925	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GW13_RS14930	COG0456	acetyltransferase
GW13_RS14935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GW13_RS14940	COG2244	polysaccharide biosynthetic process
GW13_RS14985	COG3071	HemY protein
GW13_RS14990	COG2959	enzyme of heme biosynthesis
GW13_RS15055	COG1011	Hydrolase
GW13_RS15105	COG1280	lysine exporter protein (LysE YggA)
GW13_RS15110	COG1280	lysine exporter protein (LysE YggA)
GW13_RS15115	COG2267	carboxylic ester hydrolase activity
GW13_RS15120	COG0561	phosphatase activity
GW13_RS15140	COG0641	radical SAM
GW13_RS15185	COG0805	protein transport
GW13_RS15230	COG1739	Uncharacterized protein family UPF0029
GW13_RS15280	COG1763	Mo-molybdopterin cofactor biosynthetic process
GW13_RS15290	COG3084	Protein conserved in bacteria
GW13_RS15305	COG0204	Acyl-transferase
GW13_RS15375	COG0561	phosphatase activity
GW13_RS15420	COG1501	Belongs to the glycosyl hydrolase 31 family
GW13_RS15425	COG2017	converts alpha-aldose to the beta-anomer
GW13_RS15435	COG3684	Belongs to the aldolase LacD family
GW13_RS15445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GW13_RS15450	COG1349	DNA-binding transcription factor activity
GW13_RS15455	COG1011	Hydrolase
GW13_RS15470	COG0456	acetyltransferase
GW13_RS15475	COG5499	transcription regulator containing HTH domain
GW13_RS15480	COG4680	protein conserved in bacteria
GW13_RS15490	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GW13_RS15505	COG2864	formate dehydrogenase
GW13_RS15510	COG0437	4 iron, 4 sulfur cluster binding
GW13_RS15515	COG3383	formate dehydrogenase (NAD+) activity
GW13_RS15515	COG0243	molybdopterin cofactor binding
GW13_RS15520	COG3383	formate dehydrogenase (NAD+) activity
GW13_RS15520	COG0243	molybdopterin cofactor binding
GW13_RS15545	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GW13_RS15560	COG1454	alcohol dehydrogenase
GW13_RS15605	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GW13_RS15615	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GW13_RS15620	COG2258	MOSC domain
GW13_RS15630	COG2205	protein histidine kinase activity
GW13_RS15635	COG0745	RESPONSE REGULATOR receiver
GW13_RS15640	COG3678	ATP-independent chaperone mediated protein folding
GW13_RS15665	COG2211	Major facilitator Superfamily
GW13_RS15680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GW13_RS15700	COG3152	Membrane
GW13_RS15710	COG1494	fructose-1,6-bisphosphatase
GW13_RS15720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GW13_RS15735	COG1575	Belongs to the MenA family. Type 1 subfamily
GW13_RS15750	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GW13_RS15755	COG1609	Transcriptional regulator
GW13_RS15760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GW13_RS15785	COG0626	cystathionine gamma-synthase activity
GW13_RS15790	COG0527	aspartate kinase activity
GW13_RS15790	COG0460	homoserine dehydrogenase
GW13_RS15795	COG0668	transmembrane transport
GW13_RS15810	COG0737	Belongs to the 5'-nucleotidase family
GW13_RS15825	COG0371	Dehydrogenase
GW13_RS15835	COG2207	Transcriptional regulator
GW13_RS15875	COG0583	DNA-binding transcription factor activity
GW13_RS15985	COG0250	Participates in transcription elongation, termination and antitermination
GW13_RS16050	COG2104	thiamine diphosphate biosynthetic process
GW13_RS16055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GW13_RS16120	COG0151	Belongs to the GarS family
GW13_RS16160	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GW13_RS16200	COG3122	Protein conserved in bacteria
GW13_RS16205	COG1187	pseudouridine synthase activity
GW13_RS16215	COG1349	DNA-binding transcription factor activity
GW13_RS16220	COG0561	phosphatase activity
GW13_RS16245	COG0527	aspartate kinase activity
GW13_RS16270	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GW13_RS16285	COG1175	transmembrane transport
GW13_RS16325	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GW13_RS16335	COG0534	Mate efflux family protein
GW13_RS16345	COG0735	belongs to the Fur family
GW13_RS16355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GW13_RS16385	COG3700	Belongs to the class B bacterial acid phosphatase family
GW13_RS16395	COG2315	Protein conserved in bacteria
GW13_RS16460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GW13_RS16485	COG2252	PERMEase
GW13_RS16495	COG0025	NhaP-type Na H and K H
GW13_RS16500	COG0583	DNA-binding transcription factor activity
GW13_RS16505	COG1380	Effector of murein hydrolase LrgA
GW13_RS16510	COG1346	cytolysis
GW13_RS16520	COG3162	membrane
GW13_RS16525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GW13_RS16540	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GW13_RS16545	COG0437	4 iron, 4 sulfur cluster binding
GW13_RS16550	COG3301	Polysulphide reductase, NrfD
GW13_RS16555	COG1138	Cytochrome C-type biogenesis protein
GW13_RS16560	COG3088	subunit of a heme lyase
GW13_RS16565	COG4235	cytochrome complex assembly
GW13_RS16570	COG1301	dicarboxylic acid transport
GW13_RS16575	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GW13_RS16580	COG3383	formate dehydrogenase (NAD+) activity
GW13_RS16585	COG3383	formate dehydrogenase (NAD+) activity
GW13_RS16605	COG2824	Alkylphosphonate utilization operon protein PhnA
GW13_RS16630	COG0531	amino acid
GW13_RS16635	COG2207	Transcriptional regulator
GW13_RS16640	COG1982	Orn Lys Arg decarboxylase major
GW13_RS16645	COG2169	Transcriptional regulator
GW13_RS16660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GW13_RS16660	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GW13_RS16665	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GW13_RS16675	COG4565	transcriptional regulatory protein
GW13_RS16680	COG3290	protein histidine kinase activity
GW13_RS16685	COG0243	molybdopterin cofactor binding
GW13_RS16690	COG0437	4 iron, 4 sulfur cluster binding
GW13_RS16695	COG3302	dmso reductase anchor subunit
GW13_RS16700	COG3381	protein complex oligomerization
GW13_RS16720	COG2197	response regulator
GW13_RS16745	COG0671	phosphoesterase, PA-phosphatase related
GW13_RS16750	COG3423	Transcriptional regulator
GW13_RS16775	COG3501	Rhs element vgr protein
GW13_RS16780	COG3501	Rhs element vgr protein
GW13_RS16790	COG3423	Transcriptional regulator
GW13_RS16815	COG0582	viral genome integration into host DNA
GW13_RS16825	COG0582	viral genome integration into host DNA
GW13_RS16835	COG1309	transcriptional regulator
GW13_RS16850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GW13_RS16855	COG1027	Aspartate ammonia-lyase
GW13_RS16860	COG3030	protein affecting phage T7 exclusion by the F plasmid
GW13_RS16865	COG0531	amino acid
GW13_RS16905	COG5510	response to toxic substance
GW13_RS16935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GW13_RS16940	COG1053	succinate dehydrogenase
GW13_RS16960	COG3264	Mechanosensitive ion channel
GW13_RS16960	COG1511	domain protein
GW13_RS16980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GW13_RS17005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GW13_RS17005	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GW13_RS17010	COG0802	atpase or kinase
GW13_RS17035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GW13_RS17040	COG0330	HflC and HflK could
GW13_RS17045	COG0330	HflC and HflK could
GW13_RS17050	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GW13_RS17065	COG0557	exoribonuclease II activity
GW13_RS17080	COG3789	protein conserved in bacteria
GW13_RS17085	COG1842	Phage shock protein A
GW13_RS17095	COG0754	glutathionylspermidine amidase activity
GW13_RS17100	COG1960	acyl-CoA dehydrogenase activity
GW13_RS17110	COG3650	response to hydrogen peroxide
GW13_RS17115	COG1073	alpha beta
GW13_RS17185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GW13_RS17200	COG3061	Opacity-associated protein A
GW13_RS17205	COG0545	Peptidyl-prolyl cis-trans isomerase
GW13_RS17210	COG1113	amino acid transport
GW13_RS17220	COG0697	spore germination
GW13_RS17225	COG0702	epimerase
GW13_RS17230	COG1733	regulation of RNA biosynthetic process
GW13_RS17250	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GW13_RS17260	COG1253	flavin adenine dinucleotide binding
GW13_RS17280	COG2105	PFAM AIG2 family protein
GW13_RS17285	COG2271	Major facilitator Superfamily
GW13_RS17290	COG3964	amidohydrolase
GW13_RS17305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GW13_RS17315	COG0312	modulator of DNA gyrase
GW13_RS17350	COG3964	amidohydrolase
GW13_RS17365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS17365	COG3711	transcriptional antiterminator
GW13_RS17370	COG3077	Addiction module antitoxin, RelB DinJ family
GW13_RS17375	COG2026	Addiction module toxin, RelE StbE family
GW13_RS17380	COG0602	queuosine metabolic process
GW13_RS17390	COG0366	Alpha amylase catalytic
GW13_RS17395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GW13_RS17395	COG1263	PTS System
GW13_RS17440	COG1438	arginine binding
GW13_RS17445	COG1288	antiporter activity
GW13_RS17475	COG2731	YhcH YjgK YiaL family protein
GW13_RS17515	COG2927	DNA polymerase III (CHI subunit)
GW13_RS17530	COG0795	lipopolysaccharide-transporting ATPase activity
GW13_RS17535	COG0795	lipopolysaccharide-transporting ATPase activity
GW13_RS17540	COG1609	Transcriptional regulator
GW13_RS17545	COG2610	gluconate transmembrane transporter activity
GW13_RS17550	COG1028	Short-chain dehydrogenase reductase Sdr
GW13_RS17555	COG1063	alcohol dehydrogenase
GW13_RS17560	COG3265	gluconokinase activity
GW13_RS17565	COG1064	alcohol dehydrogenase
GW13_RS17660	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GW13_RS17690	COG0412	Dienelactone hydrolase
GW13_RS17700	COG2186	Transcriptional regulator
GW13_RS17725	COG0583	DNA-binding transcription factor activity
GW13_RS17730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GW13_RS17735	COG0700	Nucleoside recognition
GW13_RS17740	COG3366	ferrous iron transmembrane transporter activity
GW13_RS17750	COG0477	Major facilitator Superfamily
GW13_RS17755	COG2733	membrane
GW13_RS17765	COG5464	transposase or invertase
GW13_RS17765	COG5464	transposase or invertase
GW13_RS17770	COG1012	belongs to the aldehyde dehydrogenase family
GW13_RS17780	COG3586	endonuclease activity
GW13_RS17785	COG1280	lysine exporter protein (LysE YggA)
GW13_RS17795	COG0523	cobalamin synthesis protein
GW13_RS17800	COG2879	small protein
GW13_RS17805	COG1966	Carbon starvation protein
GW13_RS17810	COG0840	transmembrane signaling receptor activity
GW13_RS17825	COG1484	DNA-dependent DNA replication
GW13_RS17840	COG2966	Psort location CytoplasmicMembrane, score
GW13_RS17845	COG2197	response regulator
GW13_RS17850	COG2197	response regulator
GW13_RS17855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GW13_RS17860	COG4114	ferric iron reductase
GW13_RS17865	COG3706	GGDEF domain
GW13_RS17895	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GW13_RS17905	COG1011	Hydrolase
GW13_RS17915	COG2823	Periplasmic or secreted lipoprotein
GW13_RS17925	COG4667	esterase of the alpha-beta hydrolase superfamily
GW13_RS17930	COG0084	hydrolase, TatD family'
GW13_RS17935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GW13_RS17940	COG1328	CTP reductase activity
GW13_RS17965	COG1943	Transposase
GW13_RS17975	COG3726	membrane protein affecting hemolysin expression
GW13_RS17985	COG0560	Phosphoserine phosphatase
GW13_RS18000	COG0488	(ABC) transporter
GW13_RS18030	COG3708	Transcriptional regulator
GW13_RS18030	COG2207	Transcriptional regulator
GW13_RS18035	COG3045	CreA protein
GW13_RS18040	COG0745	RESPONSE REGULATOR receiver
GW13_RS18045	COG2205	protein histidine kinase activity
GW13_RS18050	COG4452	Inner membrane protein CreD
GW13_RS18070	COG3121	Chaperone
GW13_RS18090	COG0745	RESPONSE REGULATOR receiver
GW13_RS18100	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GW13_RS18110	COG0460	homoserine dehydrogenase
GW13_RS18110	COG0527	aspartate kinase activity
GW13_RS18120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GW13_RS18130	COG1115	amino acid carrier protein
GW13_RS18140	COG0521	Mo-molybdopterin cofactor biosynthetic process
GW13_RS18145	COG1584	GPR1 FUN34 yaaH family protein
GW13_RS18150	COG4735	regulation of single-species biofilm formation
GW13_RS18215	COG3188	usher protein
GW13_RS18230	COG3539	Fimbrial protein
GW13_RS18235	COG3121	Chaperone
GW13_RS18270	COG3119	arylsulfatase activity
GW13_RS18275	COG0641	radical SAM
GW13_RS18300	COG0583	DNA-binding transcription factor activity
GW13_RS18325	COG0196	riboflavin kinase activity
GW13_RS18340	COG1047	Peptidyl-prolyl cis-trans
GW13_RS18485	COG0644	oxidoreductase
GW13_RS18490	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GW13_RS18495	COG2271	Major facilitator Superfamily
GW13_RS18520	COG3119	arylsulfatase activity
GW13_RS18570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GW13_RS18580	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GW13_RS18600	COG0417	DNA replication proofreading
GW13_RS18645	COG0586	Pfam SNARE associated Golgi protein
GW13_RS18735	COG0768	penicillin binding
GW13_RS18745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GW13_RS18760	COG0772	Belongs to the SEDS family
GW13_RS18785	COG0849	cell division
GW13_RS18790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GW13_RS18810	COG0494	nUDIX hydrolase
GW13_RS18845	COG1459	type II secretion system
GW13_RS18850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GW13_RS18855	COG4969	Belongs to the N-Me-Phe pilin family
GW13_RS18875	COG3725	Membrane protein required for beta-lactamase induction
GW13_RS18880	COG3940	Belongs to the glycosyl hydrolase 43 family
GW13_RS18885	COG2211	Major facilitator Superfamily
GW13_RS18900	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GW13_RS18905	COG0508	dehydrogenase complex catalyzes the overall conversion of
GW13_RS18910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GW13_RS18925	COG3064	Membrane
GW13_RS18955	COG1349	DNA-binding transcription factor activity
GW13_RS18975	COG2132	Multicopper oxidase
GW13_RS18980	COG4993	Dehydrogenase
GW13_RS18990	COG0288	reversible hydration of carbon dioxide
GW13_RS18995	COG1131	(ABC) transporter
GW13_RS19000	COG0842	Transport permease protein
GW13_RS19005	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GW13_RS19010	COG0726	polysaccharide deacetylase
GW13_RS19030	COG3539	Fimbrial protein
GW13_RS19035	COG3188	usher protein
GW13_RS19040	COG3121	Chaperone
GW13_RS19070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GW13_RS19095	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GW13_RS19100	COG1643	Atp-dependent helicase
GW13_RS19105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GW13_RS19110	COG4774	siderophore transport
GW13_RS19115	COG1120	ATPase activity
GW13_RS19120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GW13_RS19140	COG3188	usher protein
GW13_RS19145	COG3121	Chaperone
GW13_RS19150	COG3539	Fimbrial protein
GW13_RS19155	COG3539	Fimbrial protein
GW13_RS19185	COG2860	membrane
GW13_RS19210	COG3835	regulator
GW13_RS19220	COG0477	Major facilitator Superfamily
GW13_RS19280	COG0575	Belongs to the CDS family
GW13_RS19340	COG1982	Orn Lys Arg decarboxylase major
GW13_RS19345	COG0346	lactoylglutathione lyase activity
GW13_RS19350	COG0037	tRNA processing
GW13_RS19355	COG4568	rho-dependent transcription termination
GW13_RS19370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GW13_RS19375	COG3015	lipoprotein NlpE involved in copper resistance
GW13_RS19385	COG1720	tRNA m6t6A37 methyltransferase activity
GW13_RS19410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GW13_RS19450	COG0583	DNA-binding transcription factor activity
GW13_RS19455	COG2814	Major facilitator Superfamily
GW13_RS19465	COG2226	methyltransferase
GW13_RS19470	COG0741	lytic transglycosylase activity
GW13_RS19470	COG1388	LysM domain
GW13_RS19480	COG2226	methyltransferase
GW13_RS19585	COG2885	chlorophyll binding
GW13_RS19585	COG3047	cAMP biosynthetic process
GW13_RS19650	COG3209	COG3209 Rhs family protein
GW13_RS19785	COG1522	sequence-specific DNA binding
GW13_RS19820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GW13_RS19835	COG0121	glutamine amidotransferase
GW13_RS19840	COG3034	peptidoglycan biosynthetic process
GW13_RS19850	COG1690	Belongs to the RtcB family
GW13_RS19855	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GW13_RS19860	COG2195	Cleaves the N-terminal amino acid of tripeptides
GW13_RS19900	COG0582	viral genome integration into host DNA
GW13_RS19925	COG2814	Major facilitator Superfamily
GW13_RS19940	COG0179	Fumarylacetoacetate (FAA) hydrolase
GW13_RS19970	COG3188	usher protein
GW13_RS19975	COG3121	Chaperone
GW13_RS19980	COG3539	Fimbrial protein
GW13_RS19995	COG2200	EAL domain
GW13_RS20040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GW13_RS20045	COG2217	Heavy metal translocating P-type atpase
GW13_RS20050	COG0789	Transcriptional regulator
GW13_RS20060	COG2814	Major facilitator Superfamily
GW13_RS20075	COG1271	oxidase subunit
GW13_RS20080	COG1294	oxidase, subunit
GW13_RS20100	COG1280	lysine exporter protein (LysE YggA)
GW13_RS20135	COG0113	porphobilinogen synthase activity
GW13_RS20150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GW13_RS20160	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GW13_RS20205	COG3706	GGDEF domain
GW13_RS20210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GW13_RS20230	COG4126	flavin adenine dinucleotide binding
GW13_RS20245	COG1940	carbohydrate kinase activity
GW13_RS20250	COG2814	Major facilitator Superfamily
GW13_RS20255	COG0419	ATPase involved in DNA repair
GW13_RS20260	COG0420	3'-5' exonuclease activity
GW13_RS20270	COG5002	protein histidine kinase activity
GW13_RS20285	COG0366	Alpha amylase catalytic
GW13_RS20290	COG0450	alkyl hydroperoxide reductase
GW13_RS20315	COG1862	Preprotein translocase
GW13_RS20325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GW13_RS20360	COG4238	major outer membrane lipoprotein
GW13_RS20370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GW13_RS20370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GW13_RS20390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GW13_RS20395	COG0667	Aldo Keto reductase
GW13_RS20405	COG0142	geranyltranstransferase activity
GW13_RS20430	COG3842	ATPase activity
GW13_RS20440	COG2188	Transcriptional regulator
GW13_RS20470	COG2814	Major facilitator Superfamily
GW13_RS20495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GW13_RS20500	COG1845	cytochrome c oxidase, subunit III
GW13_RS20505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GW13_RS20510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GW13_RS20515	COG2223	nitrite transmembrane transporter activity
GW13_RS20520	COG3056	Lipoprotein
GW13_RS20525	COG0271	Belongs to the BolA IbaG family
GW13_RS20550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GW13_RS20560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GW13_RS20565	COG1555	photosystem II stabilization
GW13_RS20570	COG0824	Thioesterase
GW13_RS20580	COG4533	DNA binding
GW13_RS20595	COG1522	sequence-specific DNA binding
GW13_RS20600	COG1132	(ABC) transporter
GW13_RS20605	COG1132	(ABC) transporter
GW13_RS20610	COG0347	Belongs to the P(II) protein family
GW13_RS20615	COG0004	ammonium transporteR
GW13_RS20620	COG1946	Acyl-CoA thioesterase
GW13_RS20625	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GW13_RS20630	COG3695	enzyme binding
GW13_RS20640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GW13_RS20660	COG0110	maltose O-acetyltransferase activity
GW13_RS20675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GW13_RS20680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GW13_RS20685	COG1309	transcriptional regulator
GW13_RS20690	COG3264	Mechanosensitive ion channel
GW13_RS20690	COG1196	nuclear chromosome segregation
GW13_RS20695	COG5464	transposase or invertase
GW13_RS20705	COG3923	Primosomal replication protein n
GW13_RS20710	COG2832	Protein of unknown function (DUF454)
GW13_RS20765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GW13_RS20775	COG4651	solute:proton antiporter activity
GW13_RS20775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GW13_RS20780	COG2223	nitrite transmembrane transporter activity
GW13_RS20795	COG3735	TraB family
GW13_RS20805	COG2217	Heavy metal translocating P-type atpase
GW13_RS20810	COG0789	Transcriptional regulator
GW13_RS20815	COG1585	Membrane protein implicated in regulation of membrane protease activity
GW13_RS20820	COG0330	HflC and HflK could
GW13_RS20825	COG4619	ABC transporter
GW13_RS20830	COG0390	transport system, permease component
GW13_RS20835	COG3118	belongs to the thioredoxin family
GW13_RS20840	COG0300	oxidoreductase activity
GW13_RS20845	COG2755	lipolytic protein G-D-S-L family
GW13_RS20850	COG4181	ATPase activity
GW13_RS20855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GW13_RS20865	COG1464	Belongs to the NlpA lipoprotein family
GW13_RS20885	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GW13_RS20890	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GW13_RS20905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GW13_RS20915	COG1988	membrane-bound metal-dependent
GW13_RS20920	COG2501	S4 domain
GW13_RS20995	COG0582	viral genome integration into host DNA
GW13_RS21050	COG4712	double-strand break repair protein
GW13_RS21115	COG0305	Participates in initiation and elongation during chromosome replication
GW13_RS21160	COG0484	heat shock protein binding
GW13_RS21210	COG1783	phage Terminase large subunit
GW13_RS21300	COG0463	Glycosyl transferase, family 2
GW13_RS21305	COG2246	polysaccharide biosynthetic process
GW13_RS21310	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GW13_RS21315	COG2207	Transcriptional regulator
GW13_RS21320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GW13_RS21330	COG3059	membrane
GW13_RS21340	COG1113	amino acid transport
GW13_RS21345	COG0668	transmembrane transport
GW13_RS21360	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GW13_RS21360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GW13_RS21365	COG2222	sugar isomerase
GW13_RS21375	COG3716	PTS system mannose fructose sorbose family IID component
GW13_RS21400	COG2315	Protein conserved in bacteria
GW13_RS21430	COG4771	TonB-dependent receptor
GW13_RS21435	COG2382	esterase
GW13_RS21440	COG3251	PFAM MbtH domain protein
GW13_RS21445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GW13_RS21445	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GW13_RS21450	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GW13_RS21455	COG1120	ATPase activity
GW13_RS21460	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GW13_RS21465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GW13_RS21475	COG4592	Periplasmic binding protein
GW13_RS21480	COG1169	isochorismate synthase
GW13_RS21485	COG1021	2,3-dihydroxybenzoate-AMP ligase
GW13_RS21490	COG3433	isochorismatase activity
GW13_RS21490	COG1535	isochorismatase
GW13_RS21495	COG1028	Short-chain dehydrogenase reductase Sdr
GW13_RS21505	COG1966	Carbon starvation protein
GW13_RS21510	COG2879	small protein
GW13_RS21515	COG0371	Dehydrogenase
GW13_RS21520	COG0436	Aminotransferase
GW13_RS21525	COG1475	DNA binding
GW13_RS21530	COG3969	phosphoadenosine phosphosulfate
GW13_RS21535	COG0583	DNA-binding transcription factor activity
GW13_RS21545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GW13_RS21565	COG0243	molybdopterin cofactor binding
GW13_RS21590	COG1063	alcohol dehydrogenase
GW13_RS21595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GW13_RS21605	COG3719	Belongs to the RNase T2 family
GW13_RS21610	COG0471	metal ion transport
GW13_RS21625	COG3051	citrate lyase alpha subunit
GW13_RS21630	COG2301	Belongs to the HpcH HpaI aldolase family
GW13_RS21640	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GW13_RS21645	COG3290	protein histidine kinase activity
GW13_RS21650	COG4565	transcriptional regulatory protein
GW13_RS21655	COG3069	C4-dicarboxylate transmembrane transporter activity
GW13_RS21675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GW13_RS21690	COG0583	DNA-binding transcription factor activity
GW13_RS21705	COG1686	Belongs to the peptidase S11 family
GW13_RS21715	COG0772	Belongs to the SEDS family
GW13_RS21720	COG0768	penicillin binding
GW13_RS21730	COG0799	negative regulation of ribosome biogenesis
GW13_RS21740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GW13_RS21750	COG1466	dna polymerase III delta subunit
GW13_RS21780	COG3829	transcription factor binding
GW13_RS21780	COG3290	protein histidine kinase activity
GW13_RS21785	COG2888	peptidyl-tyrosine sulfation
GW13_RS21800	COG2214	Heat shock protein DnaJ domain protein
GW13_RS21810	COG2214	Heat shock protein DnaJ domain protein
GW13_RS21815	COG0443	Heat shock 70 kDa protein
GW13_RS21830	COG1126	abc transporter atp-binding protein
GW13_RS21835	COG0765	amino acid transport
GW13_RS21840	COG0765	amino acid transport
GW13_RS21865	COG1702	phosphate starvation-inducible protein PhoH
GW13_RS21875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GW13_RS21915	COG0367	asparagine synthase
GW13_RS21925	COG0647	UMP catabolic process
GW13_RS21930	COG1940	carbohydrate kinase activity
GW13_RS21930	COG1846	Transcriptional regulator
GW13_RS21935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GW13_RS21975	COG1053	succinate dehydrogenase
GW13_RS21980	COG0583	DNA-binding transcription factor activity
GW13_RS21985	COG0735	belongs to the Fur family
GW13_RS22000	COG0596	Alpha beta hydrolase
GW13_RS22010	COG0033	Phosphoglucomutase
GW13_RS22020	COG0531	amino acid
GW13_RS22025	COG1982	Orn Lys Arg decarboxylase major
GW13_RS22030	COG0745	RESPONSE REGULATOR receiver
GW13_RS22035	COG2205	protein histidine kinase activity
GW13_RS22065	COG3157	Type VI secretion system effector, Hcp
GW13_RS22090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GW13_RS22095	COG1984	allophanate hydrolase subunit 2
GW13_RS22110	COG3180	Ammonia monooxygenase
GW13_RS22135	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GW13_RS22150	COG0567	Dehydrogenase, E1 component
GW13_RS22155	COG0508	dehydrogenase complex catalyzes the overall conversion of
GW13_RS22165	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GW13_RS22170	COG1271	oxidase subunit
GW13_RS22175	COG1294	oxidase, subunit
GW13_RS22180	COG4890	Cyd operon protein YbgT
GW13_RS22185	COG3790	cyd operon protein YbgE
GW13_RS22190	COG0824	Thioesterase
GW13_RS22195	COG0811	peptide transport
GW13_RS22200	COG0848	biopolymer transport protein
GW13_RS22205	COG3064	Membrane
GW13_RS22215	COG2885	chlorophyll binding
GW13_RS22220	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GW13_RS22270	COG1230	cation diffusion facilitator family transporter
GW13_RS22280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GW13_RS22285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GW13_RS22285	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GW13_RS22295	COG0583	DNA-binding transcription factor activity
GW13_RS22300	COG0583	DNA-binding transcription factor activity
GW13_RS22305	COG0471	metal ion transport
GW13_RS22305	COG0490	domain, Protein
GW13_RS22315	COG5016	pyruvate
GW13_RS22315	COG0511	ligase activity, forming carbon-carbon bonds
GW13_RS22320	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GW13_RS22330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GW13_RS22335	COG1120	ATPase activity
GW13_RS22350	COG2017	converts alpha-aldose to the beta-anomer
GW13_RS22375	COG1119	ATPase activity
GW13_RS22380	COG2005	Transcriptional regulator
GW13_RS22380	COG3585	molybdate ion transport
GW13_RS22390	COG0725	ABC transporter, periplasmic molybdate-binding protein
GW13_RS22395	COG4149	molybdate abc transporter
GW13_RS22405	COG0561	phosphatase activity
GW13_RS22415	COG4677	pectinesterase activity
GW13_RS22445	COG1881	PFAM PEBP family protein
GW13_RS22470	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GW13_RS22500	COG0521	Mo-molybdopterin cofactor biosynthetic process
GW13_RS22510	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GW13_RS22520	COG0670	Belongs to the BI1 family
GW13_RS22545	COG0392	lysyltransferase activity
GW13_RS22550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GW13_RS22555	COG3568	Endonuclease Exonuclease Phosphatase
GW13_RS22565	COG0842	Transport permease protein
GW13_RS22570	COG0842	Transport permease protein
GW13_RS22575	COG1131	(ABC) transporter
GW13_RS22580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GW13_RS22585	COG1309	transcriptional regulator
GW13_RS22590	COG0513	Belongs to the DEAD box helicase family
GW13_RS22600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GW13_RS22610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GW13_RS22620	COG0668	transmembrane transport
GW13_RS22625	COG1126	abc transporter atp-binding protein
GW13_RS22630	COG0765	amino acid transport
GW13_RS22635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GW13_RS22650	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GW13_RS22655	COG2194	sulfuric ester hydrolase activity
GW13_RS22670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GW13_RS22675	COG1376	ErfK ybiS ycfS ynhG family protein
GW13_RS22680	COG0488	(ABC) transporter
GW13_RS22690	COG0561	phosphatase activity
GW13_RS22695	COG1882	Formate acetyltransferase
GW13_RS22700	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GW13_RS22725	COG0747	negative chemotaxis
GW13_RS22750	COG2133	pyrroloquinoline quinone binding
GW13_RS22755	COG0625	glutathione transferase activity
GW13_RS22760	COG1686	Belongs to the peptidase S11 family
GW13_RS22765	COG1349	DNA-binding transcription factor activity
GW13_RS22770	COG0671	phosphoesterase, PA-phosphatase related
GW13_RS22775	COG2814	Major facilitator Superfamily
GW13_RS22780	COG0561	phosphatase activity
GW13_RS22785	COG0738	Major facilitator superfamily
GW13_RS22790	COG3226	Transcriptional regulator
GW13_RS22830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GW13_RS22835	COG3842	ATPase activity
GW13_RS22840	COG1176	ABC-type spermidine putrescine transport system, permease component I
GW13_RS22845	COG1177	transmembrane transport
GW13_RS22880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GW13_RS22885	COG4160	amino acid transport
GW13_RS22890	COG4215	(ABC) transporter
GW13_RS22895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GW13_RS22900	COG1126	abc transporter atp-binding protein
GW13_RS22915	COG3023	N-Acetylmuramoyl-L-alanine amidase
GW13_RS22920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GW13_RS22925	COG0702	epimerase
GW13_RS22930	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GW13_RS22935	COG0028	Belongs to the TPP enzyme family
GW13_RS22940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GW13_RS22950	COG2431	L-lysine efflux transmembrane transporter activity
GW13_RS22960	COG3593	DNA synthesis involved in DNA repair
GW13_RS22965	COG2990	Protein conserved in bacteria
GW13_RS22970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GW13_RS22975	COG0577	efflux transmembrane transporter activity
GW13_RS22975	COG1136	(ABC) transporter
GW13_RS22985	COG1278	Cold shock
GW13_RS22995	COG0542	response to heat
GW13_RS23030	COG1335	isochorismatase
GW13_RS23040	COG0583	DNA-binding transcription factor activity
GW13_RS23060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GW13_RS23065	COG4988	ABC transporter
GW13_RS23070	COG0492	ferredoxin-NADP+ reductase activity
GW13_RS23095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GW13_RS23110	COG0243	molybdopterin cofactor binding
GW13_RS23115	COG0437	4 iron, 4 sulfur cluster binding
GW13_RS23120	COG3302	dmso reductase anchor subunit
GW13_RS23130	COG0531	amino acid
GW13_RS23135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GW13_RS23145	COG1882	Formate acetyltransferase
GW13_RS23150	COG2116	formate transmembrane transporter activity
GW13_RS23155	COG1944	ATP diphosphatase activity
GW13_RS23160	COG2323	membrane
GW13_RS23175	COG0501	Belongs to the peptidase M48B family
GW13_RS23185	COG0539	negative regulation of cytoplasmic translation
GW13_RS23195	COG2333	competence protein COMEC
GW13_RS23195	COG0658	competence protein