locus-tag	class	description
IY62_RS00010	COG0527	aspartate kinase activity
IY62_RS00010	COG0460	homoserine dehydrogenase
IY62_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IY62_RS00030	COG1115	amino acid carrier protein
IY62_RS00040	COG0521	Mo-molybdopterin cofactor biosynthetic process
IY62_RS00045	COG1584	GPR1 FUN34 yaaH family protein
IY62_RS00050	COG4735	regulation of single-species biofilm formation
IY62_RS00115	COG3188	usher protein
IY62_RS00130	COG3539	Fimbrial protein
IY62_RS00135	COG3121	Chaperone
IY62_RS00155	COG0583	DNA-binding transcription factor activity
IY62_RS00170	COG0737	Belongs to the 5'-nucleotidase family
IY62_RS00180	COG3119	arylsulfatase activity
IY62_RS00185	COG0641	radical SAM
IY62_RS00205	COG0583	DNA-binding transcription factor activity
IY62_RS00230	COG0196	riboflavin kinase activity
IY62_RS00245	COG1047	Peptidyl-prolyl cis-trans
IY62_RS00395	COG0644	oxidoreductase
IY62_RS00405	COG2271	Major facilitator Superfamily
IY62_RS00430	COG3119	arylsulfatase activity
IY62_RS00470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IY62_RS00500	COG0417	DNA replication proofreading
IY62_RS00535	COG0586	Pfam SNARE associated Golgi protein
IY62_RS00630	COG0768	penicillin binding
IY62_RS00640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IY62_RS00655	COG0772	Belongs to the SEDS family
IY62_RS00680	COG0849	cell division
IY62_RS00685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IY62_RS00705	COG0494	nUDIX hydrolase
IY62_RS00710	COG0667	Aldo Keto reductase
IY62_RS00715	COG0583	DNA-binding transcription factor activity
IY62_RS00740	COG1459	type II secretion system
IY62_RS00745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IY62_RS00750	COG4969	Belongs to the N-Me-Phe pilin family
IY62_RS00765	COG3725	Membrane protein required for beta-lactamase induction
IY62_RS00770	COG3940	Belongs to the glycosyl hydrolase 43 family
IY62_RS00775	COG2211	Major facilitator Superfamily
IY62_RS00790	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IY62_RS00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
IY62_RS00800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IY62_RS00815	COG3064	Membrane
IY62_RS00855	COG1349	DNA-binding transcription factor activity
IY62_RS00875	COG2132	Multicopper oxidase
IY62_RS00880	COG4993	Dehydrogenase
IY62_RS00890	COG0288	reversible hydration of carbon dioxide
IY62_RS00895	COG1131	(ABC) transporter
IY62_RS00900	COG0842	Transport permease protein
IY62_RS00905	COG3539	Fimbrial protein
IY62_RS00925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS00930	COG0726	polysaccharide deacetylase
IY62_RS00950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IY62_RS00975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IY62_RS00980	COG1643	Atp-dependent helicase
IY62_RS00985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IY62_RS00990	COG4774	siderophore transport
IY62_RS00995	COG1120	ATPase activity
IY62_RS01000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IY62_RS01015	COG3188	usher protein
IY62_RS01020	COG3121	Chaperone
IY62_RS01025	COG3539	Fimbrial protein
IY62_RS01030	COG3539	Fimbrial protein
IY62_RS01060	COG2860	membrane
IY62_RS01085	COG3835	regulator
IY62_RS01100	COG0477	Major facilitator Superfamily
IY62_RS01150	COG0575	Belongs to the CDS family
IY62_RS01210	COG1982	Orn Lys Arg decarboxylase major
IY62_RS01215	COG0346	lactoylglutathione lyase activity
IY62_RS01225	COG4568	rho-dependent transcription termination
IY62_RS01240	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IY62_RS01245	COG3015	lipoprotein NlpE involved in copper resistance
IY62_RS01255	COG1720	tRNA m6t6A37 methyltransferase activity
IY62_RS01315	COG0656	L-ascorbic acid biosynthetic process
IY62_RS01320	COG0583	DNA-binding transcription factor activity
IY62_RS01325	COG2814	Major facilitator Superfamily
IY62_RS01335	COG2226	methyltransferase
IY62_RS01340	COG0741	lytic transglycosylase activity
IY62_RS01340	COG1388	LysM domain
IY62_RS01350	COG2226	methyltransferase
IY62_RS01400	COG3209	COG3209 Rhs family protein
IY62_RS01495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IY62_RS01510	COG0121	glutamine amidotransferase
IY62_RS01515	COG3034	peptidoglycan biosynthetic process
IY62_RS01525	COG1690	Belongs to the RtcB family
IY62_RS01530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IY62_RS01535	COG2195	Cleaves the N-terminal amino acid of tripeptides
IY62_RS01575	COG2801	Transposase and inactivated derivatives
IY62_RS01595	COG2814	Major facilitator Superfamily
IY62_RS01610	COG0179	Fumarylacetoacetate (FAA) hydrolase
IY62_RS01645	COG3188	usher protein
IY62_RS01650	COG3121	Chaperone
IY62_RS01655	COG3539	Fimbrial protein
IY62_RS01670	COG2200	EAL domain
IY62_RS01715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IY62_RS01720	COG2217	Heavy metal translocating P-type atpase
IY62_RS01725	COG0789	Transcriptional regulator
IY62_RS01740	COG2814	Major facilitator Superfamily
IY62_RS01760	COG1271	oxidase subunit
IY62_RS01765	COG1294	oxidase, subunit
IY62_RS01785	COG1280	lysine exporter protein (LysE YggA)
IY62_RS01810	COG2079	MmgE PrpD family protein
IY62_RS01820	COG0113	porphobilinogen synthase activity
IY62_RS01835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IY62_RS01840	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IY62_RS01885	COG3706	GGDEF domain
IY62_RS01890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IY62_RS01910	COG4126	flavin adenine dinucleotide binding
IY62_RS01925	COG1940	carbohydrate kinase activity
IY62_RS01930	COG2814	Major facilitator Superfamily
IY62_RS01935	COG0419	ATPase involved in DNA repair
IY62_RS01940	COG0420	3'-5' exonuclease activity
IY62_RS01955	COG5002	protein histidine kinase activity
IY62_RS01970	COG0366	Alpha amylase catalytic
IY62_RS01975	COG0450	alkyl hydroperoxide reductase
IY62_RS01995	COG1862	Preprotein translocase
IY62_RS02005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IY62_RS02035	COG4238	major outer membrane lipoprotein
IY62_RS02045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IY62_RS02045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IY62_RS02060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IY62_RS02065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IY62_RS02070	COG0667	Aldo Keto reductase
IY62_RS02080	COG0142	geranyltranstransferase activity
IY62_RS02145	COG2814	Major facilitator Superfamily
IY62_RS02165	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IY62_RS02170	COG1845	cytochrome c oxidase, subunit III
IY62_RS02175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IY62_RS02180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IY62_RS02185	COG2223	nitrite transmembrane transporter activity
IY62_RS02190	COG3056	Lipoprotein
IY62_RS02195	COG0271	Belongs to the BolA IbaG family
IY62_RS02215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IY62_RS02225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IY62_RS02230	COG1555	photosystem II stabilization
IY62_RS02235	COG0824	Thioesterase
IY62_RS02245	COG4533	DNA binding
IY62_RS02260	COG1522	sequence-specific DNA binding
IY62_RS02265	COG1132	(ABC) transporter
IY62_RS02270	COG1132	(ABC) transporter
IY62_RS02275	COG0347	Belongs to the P(II) protein family
IY62_RS02280	COG0004	ammonium transporteR
IY62_RS02285	COG1946	Acyl-CoA thioesterase
IY62_RS02290	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IY62_RS02295	COG3695	enzyme binding
IY62_RS02300	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IY62_RS02320	COG0110	maltose O-acetyltransferase activity
IY62_RS02335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IY62_RS02340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IY62_RS02345	COG1309	transcriptional regulator
IY62_RS02350	COG3264	Mechanosensitive ion channel
IY62_RS02350	COG1196	nuclear chromosome segregation
IY62_RS02355	COG5464	transposase or invertase
IY62_RS02365	COG3923	Primosomal replication protein n
IY62_RS02370	COG2832	Protein of unknown function (DUF454)
IY62_RS02415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS02420	COG4651	solute:proton antiporter activity
IY62_RS02420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IY62_RS02425	COG2223	nitrite transmembrane transporter activity
IY62_RS02440	COG3735	TraB family
IY62_RS02450	COG2217	Heavy metal translocating P-type atpase
IY62_RS02460	COG1585	Membrane protein implicated in regulation of membrane protease activity
IY62_RS02465	COG0330	HflC and HflK could
IY62_RS02470	COG4619	ABC transporter
IY62_RS02475	COG0390	transport system, permease component
IY62_RS02480	COG3118	belongs to the thioredoxin family
IY62_RS02485	COG0300	oxidoreductase activity
IY62_RS02490	COG2755	lipolytic protein G-D-S-L family
IY62_RS02495	COG4181	ATPase activity
IY62_RS02500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IY62_RS02510	COG1464	Belongs to the NlpA lipoprotein family
IY62_RS02545	COG3960	tartronate-semialdehyde synthase activity
IY62_RS02550	COG3622	Belongs to the hyi family
IY62_RS02555	COG2084	Dehydrogenase
IY62_RS02565	COG1953	Uracil, thiamine, allantoin
IY62_RS02575	COG2233	PERMEase
IY62_RS02580	COG1929	Belongs to the glycerate kinase type-1 family
IY62_RS02585	COG3257	ureidoglycine aminohydrolase activity
IY62_RS02590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IY62_RS02595	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IY62_RS02600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IY62_RS02605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IY62_RS02615	COG0549	Belongs to the carbamate kinase family
IY62_RS02620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IY62_RS02625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IY62_RS02635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IY62_RS02655	COG1988	membrane-bound metal-dependent
IY62_RS02660	COG2501	S4 domain
IY62_RS02735	COG0463	Glycosyl transferase, family 2
IY62_RS02740	COG2246	polysaccharide biosynthetic process
IY62_RS02750	COG5002	protein histidine kinase activity
IY62_RS02755	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IY62_RS02760	COG2207	Transcriptional regulator
IY62_RS02765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IY62_RS02775	COG3059	membrane
IY62_RS02785	COG1113	amino acid transport
IY62_RS02790	COG0668	transmembrane transport
IY62_RS02805	COG2315	Protein conserved in bacteria
IY62_RS02835	COG4771	TonB-dependent receptor
IY62_RS02840	COG2382	esterase
IY62_RS02845	COG3251	PFAM MbtH domain protein
IY62_RS02850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IY62_RS02850	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IY62_RS02855	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IY62_RS02860	COG1120	ATPase activity
IY62_RS02865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IY62_RS02870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IY62_RS02880	COG4592	Periplasmic binding protein
IY62_RS02885	COG1169	isochorismate synthase
IY62_RS02890	COG1021	2,3-dihydroxybenzoate-AMP ligase
IY62_RS02895	COG1535	isochorismatase
IY62_RS02895	COG3433	isochorismatase activity
IY62_RS02900	COG1028	Short-chain dehydrogenase reductase Sdr
IY62_RS02910	COG1966	Carbon starvation protein
IY62_RS02915	COG2879	small protein
IY62_RS02920	COG0371	Dehydrogenase
IY62_RS02925	COG0436	Aminotransferase
IY62_RS02930	COG1475	DNA binding
IY62_RS02940	COG0583	DNA-binding transcription factor activity
IY62_RS02945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IY62_RS02965	COG0243	molybdopterin cofactor binding
IY62_RS02985	COG1063	alcohol dehydrogenase
IY62_RS02990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IY62_RS02995	COG3719	Belongs to the RNase T2 family
IY62_RS03000	COG0471	metal ion transport
IY62_RS03015	COG3051	citrate lyase alpha subunit
IY62_RS03020	COG2301	Belongs to the HpcH HpaI aldolase family
IY62_RS03030	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IY62_RS03035	COG3290	protein histidine kinase activity
IY62_RS03040	COG4565	transcriptional regulatory protein
IY62_RS03045	COG3069	C4-dicarboxylate transmembrane transporter activity
IY62_RS03065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IY62_RS03080	COG0583	DNA-binding transcription factor activity
IY62_RS03095	COG1686	Belongs to the peptidase S11 family
IY62_RS03105	COG0772	Belongs to the SEDS family
IY62_RS03110	COG0768	penicillin binding
IY62_RS03120	COG0799	negative regulation of ribosome biogenesis
IY62_RS03145	COG1466	dna polymerase III delta subunit
IY62_RS03175	COG3290	protein histidine kinase activity
IY62_RS03175	COG3829	transcription factor binding
IY62_RS03180	COG2888	peptidyl-tyrosine sulfation
IY62_RS03195	COG2214	Heat shock protein DnaJ domain protein
IY62_RS03205	COG2214	Heat shock protein DnaJ domain protein
IY62_RS03210	COG0443	Heat shock 70 kDa protein
IY62_RS03225	COG1126	abc transporter atp-binding protein
IY62_RS03230	COG0765	amino acid transport
IY62_RS03235	COG0765	amino acid transport
IY62_RS03260	COG1702	phosphate starvation-inducible protein PhoH
IY62_RS03270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IY62_RS03315	COG0367	asparagine synthase
IY62_RS03320	COG0647	UMP catabolic process
IY62_RS03325	COG1940	carbohydrate kinase activity
IY62_RS03325	COG1846	Transcriptional regulator
IY62_RS03330	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IY62_RS03370	COG1053	succinate dehydrogenase
IY62_RS03375	COG0583	DNA-binding transcription factor activity
IY62_RS03380	COG0735	belongs to the Fur family
IY62_RS03395	COG0596	Alpha beta hydrolase
IY62_RS03405	COG0033	Phosphoglucomutase
IY62_RS03415	COG0531	amino acid
IY62_RS03420	COG1982	Orn Lys Arg decarboxylase major
IY62_RS03430	COG0745	RESPONSE REGULATOR receiver
IY62_RS03435	COG2205	protein histidine kinase activity
IY62_RS03480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IY62_RS03485	COG1984	allophanate hydrolase subunit 2
IY62_RS03500	COG3180	Ammonia monooxygenase
IY62_RS03520	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IY62_RS03535	COG0567	Dehydrogenase, E1 component
IY62_RS03540	COG0508	dehydrogenase complex catalyzes the overall conversion of
IY62_RS03550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IY62_RS03560	COG1271	oxidase subunit
IY62_RS03565	COG1294	oxidase, subunit
IY62_RS03570	COG4890	Cyd operon protein YbgT
IY62_RS03575	COG3790	cyd operon protein YbgE
IY62_RS03580	COG0824	Thioesterase
IY62_RS03585	COG0811	peptide transport
IY62_RS03590	COG0848	biopolymer transport protein
IY62_RS03595	COG3064	Membrane
IY62_RS03605	COG2885	chlorophyll binding
IY62_RS03610	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IY62_RS03650	COG1230	cation diffusion facilitator family transporter
IY62_RS03660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IY62_RS03665	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IY62_RS03665	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IY62_RS03670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IY62_RS03675	COG0583	DNA-binding transcription factor activity
IY62_RS03680	COG0583	DNA-binding transcription factor activity
IY62_RS03685	COG0490	domain, Protein
IY62_RS03685	COG0471	metal ion transport
IY62_RS03710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IY62_RS03715	COG1120	ATPase activity
IY62_RS03725	COG2017	converts alpha-aldose to the beta-anomer
IY62_RS03750	COG1119	ATPase activity
IY62_RS03755	COG2005	Transcriptional regulator
IY62_RS03755	COG3585	molybdate ion transport
IY62_RS03765	COG0725	ABC transporter, periplasmic molybdate-binding protein
IY62_RS03770	COG4149	molybdate abc transporter
IY62_RS03780	COG0561	phosphatase activity
IY62_RS03790	COG4677	pectinesterase activity
IY62_RS03820	COG1881	PFAM PEBP family protein
IY62_RS03845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IY62_RS03875	COG0521	Mo-molybdopterin cofactor biosynthetic process
IY62_RS03885	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IY62_RS03895	COG0670	Belongs to the BI1 family
IY62_RS03915	COG0392	lysyltransferase activity
IY62_RS03920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IY62_RS03925	COG3568	Endonuclease Exonuclease Phosphatase
IY62_RS03935	COG0842	Transport permease protein
IY62_RS03940	COG0842	Transport permease protein
IY62_RS03945	COG1131	(ABC) transporter
IY62_RS03955	COG1309	transcriptional regulator
IY62_RS03960	COG0513	Belongs to the DEAD box helicase family
IY62_RS03970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IY62_RS03985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IY62_RS03995	COG0668	transmembrane transport
IY62_RS04000	COG1126	abc transporter atp-binding protein
IY62_RS04005	COG0765	amino acid transport
IY62_RS04010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IY62_RS04025	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IY62_RS04030	COG2194	sulfuric ester hydrolase activity
IY62_RS04040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IY62_RS04045	COG1376	ErfK ybiS ycfS ynhG family protein
IY62_RS04050	COG0488	(ABC) transporter
IY62_RS04070	COG0561	phosphatase activity
IY62_RS04075	COG1882	Formate acetyltransferase
IY62_RS04080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IY62_RS04105	COG0747	negative chemotaxis
IY62_RS04130	COG2301	Belongs to the HpcH HpaI aldolase family
IY62_RS04145	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IY62_RS04150	COG1960	acyl-CoA dehydrogenase activity
IY62_RS04160	COG0583	DNA-binding transcription factor activity
IY62_RS04165	COG2610	gluconate transmembrane transporter activity
IY62_RS04180	COG0625	glutathione transferase activity
IY62_RS04185	COG1686	Belongs to the peptidase S11 family
IY62_RS04190	COG1349	DNA-binding transcription factor activity
IY62_RS04195	COG0671	phosphoesterase, PA-phosphatase related
IY62_RS04200	COG2814	Major facilitator Superfamily
IY62_RS04205	COG0561	phosphatase activity
IY62_RS04210	COG0738	Major facilitator superfamily
IY62_RS04215	COG3226	Transcriptional regulator
IY62_RS04255	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IY62_RS04260	COG3842	ATPase activity
IY62_RS04265	COG1176	ABC-type spermidine putrescine transport system, permease component I
IY62_RS04270	COG1177	transmembrane transport
IY62_RS04300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IY62_RS04305	COG4160	amino acid transport
IY62_RS04310	COG4215	(ABC) transporter
IY62_RS04315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IY62_RS04320	COG1126	abc transporter atp-binding protein
IY62_RS04335	COG3023	N-Acetylmuramoyl-L-alanine amidase
IY62_RS04340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IY62_RS04345	COG0702	epimerase
IY62_RS04350	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IY62_RS04355	COG0028	Belongs to the TPP enzyme family
IY62_RS04360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IY62_RS04370	COG2431	L-lysine efflux transmembrane transporter activity
IY62_RS04375	COG3593	DNA synthesis involved in DNA repair
IY62_RS04380	COG2990	Protein conserved in bacteria
IY62_RS04385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IY62_RS04390	COG0577	efflux transmembrane transporter activity
IY62_RS04390	COG1136	(ABC) transporter
IY62_RS04395	COG1278	Cold shock
IY62_RS04405	COG0542	response to heat
IY62_RS04430	COG1335	isochorismatase
IY62_RS04440	COG0583	DNA-binding transcription factor activity
IY62_RS04460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IY62_RS04465	COG4988	ABC transporter
IY62_RS04470	COG0492	ferredoxin-NADP+ reductase activity
IY62_RS04490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IY62_RS04500	COG0243	molybdopterin cofactor binding
IY62_RS04505	COG0437	4 iron, 4 sulfur cluster binding
IY62_RS04510	COG3302	dmso reductase anchor subunit
IY62_RS04525	COG0531	amino acid
IY62_RS04530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IY62_RS04545	COG1882	Formate acetyltransferase
IY62_RS04550	COG2116	formate transmembrane transporter activity
IY62_RS04555	COG1944	ATP diphosphatase activity
IY62_RS04560	COG2323	membrane
IY62_RS04575	COG0501	Belongs to the peptidase M48B family
IY62_RS04585	COG0539	negative regulation of cytoplasmic translation
IY62_RS04595	COG0658	competence protein
IY62_RS04595	COG2333	competence protein COMEC
IY62_RS04610	COG3214	Protein conserved in bacteria
IY62_RS04625	COG3173	Aminoglycoside phosphotransferase
IY62_RS04630	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IY62_RS04635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IY62_RS04645	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IY62_RS04655	COG2989	Protein conserved in bacteria
IY62_RS04660	COG3108	Peptidase M15
IY62_RS04665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IY62_RS04675	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IY62_RS04680	COG0017	Asparaginyl-tRNA synthetase
IY62_RS04685	COG1522	sequence-specific DNA binding
IY62_RS04695	COG1115	amino acid carrier protein
IY62_RS04705	COG0582	viral genome integration into host DNA
IY62_RS04720	COG5301	cellulose 1,4-beta-cellobiosidase activity
IY62_RS04740	COG4372	Transposase
IY62_RS04745	COG2135	peptidase activity
IY62_RS04765	COG0308	aminopeptidase N
IY62_RS04780	COG0633	Ferredoxin
IY62_RS04780	COG3217	Mosc domain protein beta barrel domain protein
IY62_RS04790	COG0488	(ABC) transporter
IY62_RS04795	COG2995	paraquat-inducible protein a
IY62_RS04800	COG3008	intermembrane lipid transfer
IY62_RS04800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IY62_RS04805	COG3009	Protein conserved in bacteria
IY62_RS04810	COG3130	regulation of translation
IY62_RS04820	COG1067	ATP-dependent peptidase activity
IY62_RS04840	COG3070	regulator of competence-specific genes
IY62_RS04845	COG1289	transmembrane transporter activity
IY62_RS04850	COG3304	Inner membrane component domain
IY62_RS04855	COG0210	DNA helicase
IY62_RS04870	COG1832	CoA-binding protein
IY62_RS04885	COG1881	PFAM PEBP family protein
IY62_RS04905	COG0670	Belongs to the BI1 family
IY62_RS04960	COG2205	protein histidine kinase activity
IY62_RS04965	COG0745	RESPONSE REGULATOR receiver
IY62_RS04980	COG2368	4-hydroxyphenylacetate
IY62_RS04985	COG1846	Transcriptional regulator
IY62_RS04995	COG1012	belongs to the aldehyde dehydrogenase family
IY62_RS05000	COG3384	dioxygenase
IY62_RS05010	COG3971	2-oxopent-4-enoate hydratase activity
IY62_RS05055	COG4232	protein-disulfide reductase activity
IY62_RS05060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IY62_RS05060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IY62_RS05065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IY62_RS05085	COG3729	General stress protein
IY62_RS05090	COG1309	transcriptional regulator
IY62_RS05115	COG1702	phosphate starvation-inducible protein PhoH
IY62_RS05120	COG1737	Transcriptional regulator
IY62_RS05125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IY62_RS05145	COG2814	Major facilitator Superfamily
IY62_RS05150	COG0673	inositol 2-dehydrogenase activity
IY62_RS05190	COG3157	Type VI secretion system effector, Hcp
IY62_RS05260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IY62_RS05270	COG1418	mRNA catabolic process
IY62_RS05275	COG0270	DNA (cytosine-5-)-methyltransferase activity
IY62_RS05280	COG3727	T/G mismatch-specific endonuclease activity
IY62_RS05285	COG0697	spore germination
IY62_RS05290	COG2354	Protein conserved in bacteria
IY62_RS05295	COG5475	Uncharacterized small protein (DUF2158)
IY62_RS05400	COG0425	Belongs to the sulfur carrier protein TusA family
IY62_RS05460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IY62_RS05470	COG0765	amino acid transport
IY62_RS05475	COG1126	abc transporter atp-binding protein
IY62_RS05480	COG2197	response regulator
IY62_RS05495	COG2197	response regulator
IY62_RS05540	COG3318	Belongs to the UPF0149 family
IY62_RS05540	COG3012	SEC-C Motif Domain Protein
IY62_RS05545	COG0814	amino acid
IY62_RS05555	COG1528	Iron-storage protein
IY62_RS05570	COG1528	Iron-storage protein
IY62_RS05580	COG1172	Belongs to the binding-protein-dependent transport system permease family
IY62_RS05675	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IY62_RS05690	COG3102	Protein conserved in bacteria
IY62_RS05710	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IY62_RS05715	COG1801	Protein of unknown function DUF72
IY62_RS05720	COG1335	isochorismatase
IY62_RS05730	COG0494	nUDIX hydrolase
IY62_RS05765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IY62_RS05775	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IY62_RS05780	COG0739	heme binding
IY62_RS05785	COG1560	Kdo2-lipid A biosynthetic process
IY62_RS05795	COG1737	Transcriptional regulator
IY62_RS05800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IY62_RS05805	COG0129	dihydroxy-acid dehydratase activity
IY62_RS05810	COG0800	Aldolase
IY62_RS05820	COG3141	response to X-ray
IY62_RS05830	COG2979	Protein of unknown function (DUF533)
IY62_RS05835	COG1770	oligopeptidase
IY62_RS05840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IY62_RS05845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IY62_RS05855	COG2372	response to copper ion
IY62_RS05860	COG1276	copper resistance
IY62_RS05885	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IY62_RS06010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IY62_RS06115	COG0454	-acetyltransferase
IY62_RS06125	COG5562	phage envelope protein
IY62_RS06160	COG3008	intermembrane lipid transfer
IY62_RS06165	COG2995	paraquat-inducible protein a
IY62_RS06170	COG1956	GAF domain-containing protein
IY62_RS06190	COG2814	Major facilitator Superfamily
IY62_RS06195	COG1414	Transcriptional regulator
IY62_RS06225	COG0768	penicillin binding
IY62_RS06230	COG2226	methyltransferase
IY62_RS06245	COG3716	PTS system mannose fructose sorbose family IID component
IY62_RS06250	COG3715	PTS system
IY62_RS06255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IY62_RS06255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS06265	COG1253	flavin adenine dinucleotide binding
IY62_RS06270	COG2200	EAL domain
IY62_RS06275	COG1760	l-serine dehydratase
IY62_RS06295	COG0251	oxidation-reduction process
IY62_RS06300	COG1199	ATP-dependent helicase activity
IY62_RS06310	COG3065	identical protein binding
IY62_RS06320	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IY62_RS06330	COG2894	cell division
IY62_RS06345	COG0179	Fumarylacetoacetate (FAA) hydrolase
IY62_RS06385	COG2719	SpoVR family
IY62_RS06405	COG1619	proteins homologs of microcin C7 resistance protein MccF
IY62_RS06430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IY62_RS06440	COG1294	oxidase, subunit
IY62_RS06445	COG1271	oxidase subunit
IY62_RS06450	COG1773	rubredoxin
IY62_RS06455	COG1999	signal sequence binding
IY62_RS06460	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IY62_RS06465	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
IY62_RS06475	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IY62_RS06490	COG0012	GTP binding
IY62_RS06505	COG0659	secondary active sulfate transmembrane transporter activity
IY62_RS06555	COG0387	Pfam Sodium calcium exchanger
IY62_RS06560	COG4572	Cation transport regulator
IY62_RS06565	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IY62_RS06570	COG4932	domain protein
IY62_RS06575	COG2197	response regulator
IY62_RS06580	COG3850	Histidine kinase
IY62_RS06585	COG2223	nitrite transmembrane transporter activity
IY62_RS06590	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IY62_RS06595	COG1140	nitrate reductase beta subunit
IY62_RS06600	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IY62_RS06605	COG2181	nitrate reductase activity
IY62_RS06630	COG0788	formyltetrahydrofolate deformylase activity
IY62_RS06640	COG1752	Esterase of the alpha-beta hydrolase superfamily
IY62_RS06645	COG0745	RESPONSE REGULATOR receiver
IY62_RS06650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IY62_RS06665	COG1012	belongs to the aldehyde dehydrogenase family
IY62_RS06665	COG1454	alcohol dehydrogenase
IY62_RS06670	COG2095	MarC family integral membrane protein
IY62_RS06700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IY62_RS06715	COG2350	Protein conserved in bacteria
IY62_RS06740	COG0727	PFAM Uncharacterised protein family (UPF0153)
IY62_RS06750	COG3546	catalase activity
IY62_RS06755	COG3685	Protein conserved in bacteria
IY62_RS06760	COG3685	Protein conserved in bacteria
IY62_RS06765	COG3729	General stress protein
IY62_RS06780	COG0135	phosphoribosylanthranilate isomerase activity
IY62_RS06780	COG0134	indole-3-glycerol-phosphate synthase activity
IY62_RS06800	COG0009	L-threonylcarbamoyladenylate synthase
IY62_RS06815	COG1028	Short-chain dehydrogenase reductase Sdr
IY62_RS06820	COG0616	signal peptide processing
IY62_RS06855	COG0671	phosphoesterase, PA-phosphatase related
IY62_RS06860	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IY62_RS06865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IY62_RS06885	COG1349	DNA-binding transcription factor activity
IY62_RS06895	COG5001	Diguanylate cyclase
IY62_RS06905	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IY62_RS06905	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IY62_RS06960	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IY62_RS06965	COG1842	Phage shock protein A
IY62_RS06975	COG1983	PspC domain protein
IY62_RS06985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IY62_RS06990	COG3106	COG3106 Predicted ATPase
IY62_RS07010	COG4948	Mandelate Racemase Muconate Lactonizing
IY62_RS07015	COG2866	Carboxypeptidase
IY62_RS07020	COG4166	transmembrane transport
IY62_RS07030	COG0583	DNA-binding transcription factor activity
IY62_RS07035	COG0656	L-ascorbic acid biosynthetic process
IY62_RS07040	COG1028	Short-chain dehydrogenase reductase Sdr
IY62_RS07045	COG1309	transcriptional regulator
IY62_RS07085	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IY62_RS07105	COG0668	transmembrane transport
IY62_RS07110	COG3182	Iron-regulated membrane protein
IY62_RS07130	COG2840	Smr protein MutS2
IY62_RS07135	COG0840	transmembrane signaling receptor activity
IY62_RS07145	COG0513	Belongs to the DEAD box helicase family
IY62_RS07155	COG0582	viral genome integration into host DNA
IY62_RS07250	COG0582	viral genome integration into host DNA
IY62_RS07260	COG2076	Multidrug Resistance protein
IY62_RS07275	COG0674	pyruvate-flavodoxin oxidoreductase activity
IY62_RS07275	COG1013	pyruvate-flavodoxin oxidoreductase activity
IY62_RS07275	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IY62_RS07275	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IY62_RS07285	COG3042	response to heat
IY62_RS07290	COG3187	Heat shock protein
IY62_RS07295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IY62_RS07300	COG2911	Protein conserved in bacteria
IY62_RS07310	COG3784	Protein of unknown function (DUF1318)
IY62_RS07325	COG1643	Atp-dependent helicase
IY62_RS07330	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IY62_RS07335	COG3038	cytochrome b561
IY62_RS07340	COG0500	methyltransferase
IY62_RS07355	COG0765	amino acid transport
IY62_RS07365	COG0765	amino acid transport
IY62_RS07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IY62_RS07400	COG0840	transmembrane signaling receptor activity
IY62_RS07405	COG0583	DNA-binding transcription factor activity
IY62_RS07410	COG5383	Protein conserved in bacteria
IY62_RS07415	COG2272	Belongs to the type-B carboxylesterase lipase family
IY62_RS07425	COG2353	YceI-like domain
IY62_RS07435	COG1063	alcohol dehydrogenase
IY62_RS07440	COG2271	Major facilitator Superfamily
IY62_RS07445	COG1028	Short-chain dehydrogenase reductase Sdr
IY62_RS07460	COG1349	DNA-binding transcription factor activity
IY62_RS07465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IY62_RS07470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS07475	COG0434	BtpA family
IY62_RS07480	COG3775	system Galactitol-specific IIC component
IY62_RS07485	COG3414	Phosphotransferase system galactitol-specific IIB component
IY62_RS07495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IY62_RS07500	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IY62_RS07505	COG1275	C4-dicarboxylate transporter malic acid transport protein
IY62_RS07510	COG0500	methyltransferase
IY62_RS07520	COG3135	benzoate transporter
IY62_RS07525	COG1396	sequence-specific DNA binding
IY62_RS07530	COG0826	peptidase U32
IY62_RS07555	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IY62_RS07560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IY62_RS07595	COG3238	Protein conserved in bacteria
IY62_RS07605	COG2130	NADP-dependent
IY62_RS07610	COG1802	Transcriptional regulator
IY62_RS07615	COG4772	TonB-dependent receptor
IY62_RS07650	COG2181	nitrate reductase activity
IY62_RS07660	COG1140	nitrate reductase beta subunit
IY62_RS07665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IY62_RS07700	COG0243	molybdopterin cofactor binding
IY62_RS07700	COG3383	formate dehydrogenase (NAD+) activity
IY62_RS07705	COG3383	formate dehydrogenase (NAD+) activity
IY62_RS07705	COG0243	molybdopterin cofactor binding
IY62_RS07710	COG0437	4 iron, 4 sulfur cluster binding
IY62_RS07715	COG2864	formate dehydrogenase
IY62_RS07720	COG1064	alcohol dehydrogenase
IY62_RS07740	COG1764	response to oxidative stress
IY62_RS07755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IY62_RS07770	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IY62_RS07775	COG1757	Na H antiporter
IY62_RS07780	COG1609	Transcriptional regulator
IY62_RS07800	COG0251	oxidation-reduction process
IY62_RS07805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IY62_RS07830	COG2271	Major facilitator Superfamily
IY62_RS07835	COG1063	alcohol dehydrogenase
IY62_RS07840	COG2186	Transcriptional regulator
IY62_RS07850	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IY62_RS07855	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IY62_RS07880	COG1773	rubredoxin
IY62_RS07905	COG3781	membrane
IY62_RS07920	COG1012	belongs to the aldehyde dehydrogenase family
IY62_RS07925	COG0583	DNA-binding transcription factor activity
IY62_RS07960	COG2814	Major facilitator Superfamily
IY62_RS07970	COG3111	PFAM Bacterial OB fold (BOF) protein
IY62_RS07975	COG1546	Belongs to the CinA family
IY62_RS07980	COG3729	General stress protein
IY62_RS07990	COG4221	oxidoreductase activity
IY62_RS07995	COG1802	Transcriptional regulator
IY62_RS08005	COG0246	Mannitol dehydrogenase
IY62_RS08010	COG0477	Major facilitator Superfamily
IY62_RS08015	COG1063	alcohol dehydrogenase
IY62_RS08035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IY62_RS08050	COG0243	molybdopterin cofactor binding
IY62_RS08055	COG0243	molybdopterin cofactor binding
IY62_RS08060	COG0437	4 iron, 4 sulfur cluster binding
IY62_RS08065	COG3302	dmso reductase anchor subunit
IY62_RS08105	COG1940	carbohydrate kinase activity
IY62_RS08110	COG0583	DNA-binding transcription factor activity
IY62_RS08115	COG2814	Major facilitator Superfamily
IY62_RS08125	COG3591	Belongs to the peptidase S1B family
IY62_RS08140	COG0628	permease
IY62_RS08145	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IY62_RS08150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IY62_RS08160	COG0531	amino acid
IY62_RS08165	COG3136	membrane protein required for alginate biosynthesis
IY62_RS08170	COG0745	RESPONSE REGULATOR receiver
IY62_RS08180	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IY62_RS08190	COG2205	protein histidine kinase activity
IY62_RS08215	COG5339	Protein conserved in bacteria
IY62_RS08220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IY62_RS08220	COG1263	PTS System
IY62_RS08230	COG0673	inositol 2-dehydrogenase activity
IY62_RS08280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IY62_RS08290	COG0625	glutathione transferase activity
IY62_RS08310	COG3895	Periplasmic Protein
IY62_RS08335	COG1566	PFAM secretion protein HlyD family protein
IY62_RS08350	COG4989	oxidoreductase activity
IY62_RS08355	COG3313	Fe-S protein
IY62_RS08360	COG1309	transcriptional regulator
IY62_RS08365	COG1902	pentaerythritol trinitrate reductase activity
IY62_RS08380	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IY62_RS08385	COG0791	NLP P60 protein
IY62_RS08400	COG0583	DNA-binding transcription factor activity
IY62_RS08405	COG2814	Major facilitator Superfamily
IY62_RS08410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IY62_RS08415	COG0307	riboflavin synthase, alpha
IY62_RS08595	COG0789	Transcriptional regulator
IY62_RS08600	COG3272	Protein of unknown function (DUF1722)
IY62_RS08635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS08645	COG2267	carboxylic ester hydrolase activity
IY62_RS08650	COG0531	amino acid
IY62_RS08670	COG1376	ErfK ybiS ycfS ynhG family protein
IY62_RS08685	COG0719	Fe-S assembly protein
IY62_RS08690	COG0396	ATPase activity
IY62_RS08695	COG0719	Fe-S assembly protein
IY62_RS08700	COG0316	Belongs to the HesB IscA family
IY62_RS08705	COG1823	symporter activity
IY62_RS08715	COG2050	protein possibly involved in aromatic compounds catabolism
IY62_RS08720	COG0277	FAD linked oxidase domain protein
IY62_RS08720	COG0247	lactate metabolic process
IY62_RS08725	COG0628	permease
IY62_RS08735	COG0738	Major facilitator superfamily
IY62_RS08740	COG2271	Major facilitator Superfamily
IY62_RS08755	COG4670	ketone body catabolic process
IY62_RS08760	COG1960	acyl-CoA dehydrogenase activity
IY62_RS08765	COG1917	Cupin 2, conserved barrel domain protein
IY62_RS08765	COG2207	Transcriptional regulator
IY62_RS08770	COG2086	electron transfer activity
IY62_RS08780	COG0644	oxidoreductase
IY62_RS08785	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IY62_RS08790	COG0318	PFAM AMP-dependent synthetase and ligase
IY62_RS08795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IY62_RS08795	COG0574	Belongs to the PEP-utilizing enzyme family
IY62_RS08810	COG4256	Hemin uptake protein
IY62_RS08825	COG0791	NLP P60 protein
IY62_RS08835	COG0386	Belongs to the glutathione peroxidase family
IY62_RS08910	COG3137	Salt-induced outer membrane protein
IY62_RS08915	COG1105	Belongs to the carbohydrate kinase PfkB family
IY62_RS08925	COG3001	Fructosamine kinase
IY62_RS08935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IY62_RS08940	COG1988	membrane-bound metal-dependent
IY62_RS08945	COG1823	symporter activity
IY62_RS08955	COG0753	catalase activity
IY62_RS08965	COG1486	melibiose metabolic process
IY62_RS08970	COG2169	Transcriptional regulator
IY62_RS08970	COG1917	Cupin 2, conserved barrel domain protein
IY62_RS08975	COG1447	Phosphotransferase system cellobiose-specific component IIA
IY62_RS08980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IY62_RS08985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IY62_RS08990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IY62_RS09000	COG0322	excinuclease ABC activity
IY62_RS09005	COG3678	ATP-independent chaperone mediated protein folding
IY62_RS09040	COG0494	nUDIX hydrolase
IY62_RS09055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IY62_RS09065	COG0778	Nitroreductase
IY62_RS09070	COG0616	signal peptide processing
IY62_RS09075	COG0252	asparaginase activity
IY62_RS09080	COG1335	isochorismatase
IY62_RS09085	COG2814	Major facilitator Superfamily
IY62_RS09090	COG1349	DNA-binding transcription factor activity
IY62_RS09095	COG0667	Aldo Keto reductase
IY62_RS09100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS09105	COG0191	fructose-bisphosphate aldolase activity
IY62_RS09110	COG1063	alcohol dehydrogenase
IY62_RS09115	COG2271	Major facilitator Superfamily
IY62_RS09120	COG1063	alcohol dehydrogenase
IY62_RS09125	COG3139	Protein of unknown function (DUF1315)
IY62_RS09145	COG0656	L-ascorbic acid biosynthetic process
IY62_RS09150	COG0641	radical SAM
IY62_RS09155	COG3713	MltA-interacting MipA family protein
IY62_RS09160	COG2766	serine protein kinase
IY62_RS09170	COG2199	diguanylate cyclase activity
IY62_RS09175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IY62_RS09190	COG2207	Transcriptional regulator
IY62_RS09195	COG2807	transmembrane transport
IY62_RS09200	COG3189	MarR family transcriptional regulator
IY62_RS09210	COG3042	response to heat
IY62_RS09215	COG2261	transglycosylase associated protein
IY62_RS09235	COG3615	Tellurite resistance protein tehB
IY62_RS09245	COG1605	Chorismate mutase
IY62_RS09255	COG0789	Transcriptional regulator
IY62_RS09270	COG3443	Belongs to the bacterial solute-binding protein 9 family
IY62_RS09285	COG0668	transmembrane transport
IY62_RS09290	COG1124	(ABC) transporter
IY62_RS09320	COG3038	cytochrome b561
IY62_RS09335	COG0071	Belongs to the small heat shock protein (HSP20) family
IY62_RS09425	COG0538	isocitrate dehydrogenase activity
IY62_RS09455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IY62_RS09470	COG2850	peptidyl-arginine hydroxylation
IY62_RS09500	COG1177	transmembrane transport
IY62_RS09520	COG4591	ABC-type transport system involved in lipoprotein release permease component
IY62_RS09525	COG1136	(ABC) transporter
IY62_RS09530	COG4591	ABC-type transport system involved in lipoprotein release permease component
IY62_RS09535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IY62_RS09540	COG1376	ErfK ybiS ycfS ynhG family protein
IY62_RS09540	COG1388	LysM domain
IY62_RS09550	COG1309	transcriptional regulator
IY62_RS09555	COG3134	Outer membrane lipoprotein
IY62_RS09560	COG1252	NADH dehydrogenase
IY62_RS09585	COG5633	Lipoprotein
IY62_RS09590	COG0537	adenosine 5'-monophosphoramidase activity
IY62_RS09595	COG4773	Receptor
IY62_RS09605	COG0084	hydrolase, TatD family'
IY62_RS09610	COG0470	DNA polymerase III
IY62_RS09620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IY62_RS09625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IY62_RS09630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IY62_RS09695	COG1530	ribonuclease E activity
IY62_RS09785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IY62_RS09795	COG2999	glutathione oxidoreductase activity
IY62_RS09830	COG3038	cytochrome b561
IY62_RS09845	COG1560	Kdo2-lipid A biosynthetic process
IY62_RS09860	COG5645	(Lipo)protein
IY62_RS09880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IY62_RS09935	COG3381	protein complex oligomerization
IY62_RS09965	COG3547	Transposase (IS116 IS110 IS902 family)
IY62_RS09990	COG0582	viral genome integration into host DNA
IY62_RS10005	COG0582	viral genome integration into host DNA
IY62_RS10170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IY62_RS10200	COG0534	Mate efflux family protein
IY62_RS10240	COG1122	ATPase activity
IY62_RS10370	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IY62_RS10385	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IY62_RS10400	COG1454	alcohol dehydrogenase
IY62_RS10400	COG1012	belongs to the aldehyde dehydrogenase family
IY62_RS10405	COG4656	Part of a membrane complex involved in electron transport
IY62_RS10440	COG1289	transmembrane transporter activity
IY62_RS10475	COG2925	Exonuclease
IY62_RS10480	COG0531	amino acid
IY62_RS10485	COG0583	DNA-binding transcription factor activity
IY62_RS10490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IY62_RS10580	COG2244	polysaccharide biosynthetic process
IY62_RS10585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IY62_RS10590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IY62_RS10605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IY62_RS10650	COG2327	Polysaccharide pyruvyl transferase
IY62_RS10655	COG2244	polysaccharide biosynthetic process
IY62_RS10660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IY62_RS10675	COG0297	glycogen (starch) synthase activity
IY62_RS10685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IY62_RS10690	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IY62_RS10695	COG0110	maltose O-acetyltransferase activity
IY62_RS10700	COG1216	Glycosyl transferase, family 2
IY62_RS10710	COG0438	transferase activity, transferring glycosyl groups
IY62_RS10715	COG1045	serine acetyltransferase
IY62_RS10720	COG0463	Glycosyl transferase, family 2
IY62_RS10740	COG1253	flavin adenine dinucleotide binding
IY62_RS10745	COG2982	Protein involved in outer membrane biogenesis
IY62_RS10760	COG3447	MASE1 domain protein
IY62_RS10760	COG5001	Diguanylate cyclase
IY62_RS10760	COG5002	protein histidine kinase activity
IY62_RS10765	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IY62_RS10770	COG0443	Heat shock 70 kDa protein
IY62_RS10795	COG2205	protein histidine kinase activity
IY62_RS10800	COG0745	RESPONSE REGULATOR receiver
IY62_RS10820	COG0826	peptidase U32
IY62_RS10845	COG1830	Aldolase
IY62_RS10850	COG2211	Major facilitator Superfamily
IY62_RS10855	COG1397	ADP-ribosylglycohydrolase
IY62_RS10860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS10865	COG2188	Transcriptional regulator
IY62_RS10880	COG5455	response to cobalt ion
IY62_RS10885	COG3539	Fimbrial protein
IY62_RS10890	COG3188	usher protein
IY62_RS10895	COG3121	Chaperone
IY62_RS10920	COG4808	Protein conserved in bacteria
IY62_RS10930	COG4807	Protein conserved in bacteria
IY62_RS10940	COG3275	phosphorelay sensor kinase activity
IY62_RS10955	COG1174	glycine betaine transport
IY62_RS10960	COG1125	glycine betaine transport
IY62_RS10965	COG1174	glycine betaine transport
IY62_RS10970	COG1732	Glycine betaine
IY62_RS10980	COG0277	FAD linked oxidase domain protein
IY62_RS10985	COG1686	Belongs to the peptidase S11 family
IY62_RS10995	COG0586	Pfam SNARE associated Golgi protein
IY62_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
IY62_RS11005	COG1538	Outer membrane efflux protein
IY62_RS11015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IY62_RS11020	COG0625	glutathione transferase activity
IY62_RS11035	COG2271	Major facilitator Superfamily
IY62_RS11050	COG1346	cytolysis
IY62_RS11060	COG2949	membrane
IY62_RS11070	COG0493	'glutamate synthase
IY62_RS11100	COG2311	Membrane
IY62_RS11120	COG1760	l-serine dehydratase
IY62_RS11125	COG0560	Phosphoserine phosphatase
IY62_RS11130	COG2271	Major facilitator Superfamily
IY62_RS11135	COG4771	TonB-dependent receptor
IY62_RS11140	COG0833	amino acid
IY62_RS11145	COG0583	DNA-binding transcription factor activity
IY62_RS11150	COG2855	membrane
IY62_RS11160	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IY62_RS11160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IY62_RS11160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IY62_RS11165	COG1105	Belongs to the carbohydrate kinase PfkB family
IY62_RS11200	COG0523	cobalamin synthesis protein
IY62_RS11205	COG0671	phosphoesterase, PA-phosphatase related
IY62_RS11210	COG0791	NLP P60 protein
IY62_RS11215	COG2200	EAL domain
IY62_RS11220	COG4166	transmembrane transport
IY62_RS11225	COG4174	ABC transporter (Permease)
IY62_RS11230	COG4239	(ABC) transporter, permease
IY62_RS11235	COG4172	Belongs to the ABC transporter superfamily
IY62_RS11250	COG2814	Major facilitator Superfamily
IY62_RS11260	COG1061	Type III restriction enzyme res subunit
IY62_RS11325	COG2197	response regulator
IY62_RS11330	COG3088	subunit of a heme lyase
IY62_RS11330	COG4235	cytochrome complex assembly
IY62_RS11340	COG1138	Cytochrome C-type biogenesis protein
IY62_RS11350	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IY62_RS11355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IY62_RS11360	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IY62_RS11370	COG3005	denitrification pathway
IY62_RS11375	COG3043	anaerobic respiration
IY62_RS11380	COG0348	domain, Protein
IY62_RS11385	COG0437	4 iron, 4 sulfur cluster binding
IY62_RS11395	COG3062	negative regulation of establishment of protein localization
IY62_RS11400	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IY62_RS11400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IY62_RS11410	COG4615	Cyclic peptide transporter
IY62_RS11435	COG0642	Histidine kinase
IY62_RS11435	COG2198	Histidine kinase
IY62_RS11455	COG4948	Mandelate Racemase Muconate Lactonizing
IY62_RS11485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IY62_RS11490	COG2814	Major facilitator Superfamily
IY62_RS11495	COG0583	DNA-binding transcription factor activity
IY62_RS11500	COG0584	glycerophosphoryl diester phosphodiesterase
IY62_RS11505	COG2271	Major facilitator Superfamily
IY62_RS11510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IY62_RS11520	COG0247	lactate metabolic process
IY62_RS11540	COG2271	Major facilitator Superfamily
IY62_RS11550	COG1414	Transcriptional regulator
IY62_RS11640	COG1169	isochorismate synthase
IY62_RS11645	COG4575	ribosome binding
IY62_RS11650	COG2153	protein acetylation
IY62_RS11660	COG0835	chemotaxis
IY62_RS11660	COG0784	Response regulator, receiver
IY62_RS11665	COG2304	oxidoreductase activity
IY62_RS11675	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IY62_RS11680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IY62_RS11690	COG0839	Belongs to the complex I subunit 6 family
IY62_RS11740	COG0583	DNA-binding transcription factor activity
IY62_RS11750	COG0436	Aminotransferase
IY62_RS11760	COG0490	domain, Protein
IY62_RS11760	COG0471	metal ion transport
IY62_RS11765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IY62_RS11790	COG1288	antiporter activity
IY62_RS11795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IY62_RS11800	COG3959	Transketolase, thiamine diphosphate binding domain
IY62_RS11805	COG3037	sugar-specific permease SgaT UlaA
IY62_RS11815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS11825	COG1609	Transcriptional regulator
IY62_RS11835	COG0622	Phosphoesterase
IY62_RS11840	COG0625	glutathione transferase activity
IY62_RS11845	COG0625	glutathione transferase activity
IY62_RS11850	COG1090	epimerase
IY62_RS11885	COG0833	amino acid
IY62_RS11890	COG3457	Alanine racemase
IY62_RS11895	COG0531	amino acid
IY62_RS11905	COG3829	transcription factor binding
IY62_RS11910	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IY62_RS11915	COG1286	toxin biosynthetic process
IY62_RS11920	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IY62_RS11925	COG0285	dihydrofolate synthase activity
IY62_RS11935	COG0586	Pfam SNARE associated Golgi protein
IY62_RS11945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IY62_RS11970	COG3423	Transcriptional regulator
IY62_RS11990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IY62_RS12005	COG3101	peptidyl-lysine hydroxylation
IY62_RS12010	COG0730	response to heat
IY62_RS12035	COG2062	phosphohistidine phosphatase, SixA
IY62_RS12050	COG3691	Protein conserved in bacteria
IY62_RS12065	COG2116	formate transmembrane transporter activity
IY62_RS12075	COG2246	polysaccharide biosynthetic process
IY62_RS12080	COG0463	Glycosyl transferase, family 2
IY62_RS12085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IY62_RS12085	COG2755	lipolytic protein G-D-S-L family
IY62_RS12130	COG1560	Kdo2-lipid A biosynthetic process
IY62_RS12135	COG0436	Aminotransferase
IY62_RS12150	COG3961	Belongs to the TPP enzyme family
IY62_RS12155	COG0667	Aldo Keto reductase
IY62_RS12170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IY62_RS12175	COG2200	EAL domain
IY62_RS12175	COG2199	diguanylate cyclase activity
IY62_RS12190	COG3415	Transposase
IY62_RS12195	COG3415	Transposase
IY62_RS12225	COG0583	DNA-binding transcription factor activity
IY62_RS12235	COG2211	Major facilitator Superfamily
IY62_RS12240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IY62_RS12250	COG0583	DNA-binding transcription factor activity
IY62_RS12255	COG0385	Bile acid
IY62_RS12260	COG3530	Putative quorum-sensing-regulated virulence factor
IY62_RS12290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS12345	COG4208	sulfate ABC transporter
IY62_RS12365	COG2837	iron assimilation
IY62_RS12495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IY62_RS12505	COG5342	invasion associated locus B
IY62_RS12520	COG0493	'glutamate synthase
IY62_RS12520	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IY62_RS12525	COG3850	Histidine kinase
IY62_RS12530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IY62_RS12535	COG1393	Belongs to the ArsC family
IY62_RS12555	COG2321	neutral zinc metallopeptidase
IY62_RS12565	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IY62_RS12570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IY62_RS12575	COG2716	regulation of RNA biosynthetic process
IY62_RS12580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IY62_RS12585	COG1929	Belongs to the glycerate kinase type-1 family
IY62_RS12590	COG2610	gluconate transmembrane transporter activity
IY62_RS12595	COG3835	regulator
IY62_RS12600	COG0628	permease
IY62_RS12610	COG1393	Belongs to the ArsC family
IY62_RS12620	COG2233	PERMEase
IY62_RS12635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IY62_RS12650	COG2200	EAL domain
IY62_RS12675	COG2801	Transposase and inactivated derivatives
IY62_RS12685	COG0517	IMP dehydrogenase activity
IY62_RS12685	COG0516	GMP reductase activity
IY62_RS12720	COG1645	bacterial-type flagellum-dependent swarming motility
IY62_RS12735	COG2976	Protein conserved in bacteria
IY62_RS12775	COG0437	4 iron, 4 sulfur cluster binding
IY62_RS12780	COG0243	molybdopterin cofactor binding
IY62_RS12785	COG4953	penicillin-binding protein 1C
IY62_RS12790	COG2373	Large extracellular alpha-helical protein
IY62_RS12795	COG2897	thiosulfate sulfurtransferase activity
IY62_RS12815	COG2975	iron-sulfur cluster assembly
IY62_RS12820	COG0633	Ferredoxin
IY62_RS12840	COG0822	iron-sulfur transferase activity
IY62_RS12885	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IY62_RS12895	COG3711	transcriptional antiterminator
IY62_RS12900	COG2814	Major facilitator Superfamily
IY62_RS12910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IY62_RS12910	COG1017	nitric oxide dioxygenase activity
IY62_RS12915	COG3710	Transcriptional regulator
IY62_RS12920	COG0531	amino acid
IY62_RS12930	COG3104	oligopeptide transport
IY62_RS12935	COG0347	Belongs to the P(II) protein family
IY62_RS12940	COG2204	response regulator
IY62_RS12945	COG3170	Tfp pilus assembly protein FimV
IY62_RS12950	COG2205	protein histidine kinase activity
IY62_RS12975	COG0560	Phosphoserine phosphatase
IY62_RS12980	COG1263	PTS System
IY62_RS12980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IY62_RS12990	COG1737	Transcriptional regulator
IY62_RS12995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IY62_RS13000	COG2223	nitrite transmembrane transporter activity
IY62_RS13005	COG0583	DNA-binding transcription factor activity
IY62_RS13010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IY62_RS13050	COG3086	response to oxidative stress
IY62_RS13070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IY62_RS13080	COG0513	Belongs to the DEAD box helicase family
IY62_RS13085	COG0583	DNA-binding transcription factor activity
IY62_RS13105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IY62_RS13110	COG3118	belongs to the thioredoxin family
IY62_RS13115	COG3148	PFAM DTW domain containing protein
IY62_RS13125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IY62_RS13130	COG5544	Lipoprotein
IY62_RS13135	COG0477	Major facilitator Superfamily
IY62_RS13165	COG0542	response to heat
IY62_RS13180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IY62_RS13185	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IY62_RS13190	COG0077	Prephenate dehydratase
IY62_RS13190	COG1605	Chorismate mutase
IY62_RS13200	COG1605	Chorismate mutase
IY62_RS13200	COG0287	Prephenate dehydrogenase
IY62_RS13215	COG2199	diguanylate cyclase activity
IY62_RS13240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IY62_RS13245	COG4137	Cytochrome C assembly protein
IY62_RS13250	COG4536	flavin adenine dinucleotide binding
IY62_RS13270	COG0497	DNA recombination
IY62_RS13285	COG2867	negative regulation of translational initiation
IY62_RS13310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IY62_RS13355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IY62_RS13370	COG5301	cellulose 1,4-beta-cellobiosidase activity
IY62_RS13455	COG4695	Portal protein
IY62_RS13495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IY62_RS13530	COG4974	Belongs to the 'phage' integrase family
IY62_RS13555	COG2801	Transposase and inactivated derivatives
IY62_RS13560	COG2963	transposase activity
IY62_RS13585	COG2819	hydrolase of the alpha beta superfamily
IY62_RS13605	COG2990	Protein conserved in bacteria
IY62_RS13620	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
IY62_RS13660	COG0579	oxidoreductase
IY62_RS13665	COG1012	belongs to the aldehyde dehydrogenase family
IY62_RS13670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IY62_RS13675	COG1113	amino acid transport
IY62_RS13680	COG1802	Transcriptional regulator
IY62_RS13685	COG1652	LysM domain
IY62_RS13690	COG0401	homolog of Blt101
IY62_RS13695	COG0640	Transcriptional regulator
IY62_RS13700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IY62_RS13725	COG4575	ribosome binding
IY62_RS13735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IY62_RS13780	COG2814	Major facilitator Superfamily
IY62_RS13785	COG1846	Transcriptional regulator
IY62_RS13790	COG1566	PFAM secretion protein HlyD family protein
IY62_RS13795	COG2814	Major facilitator Superfamily
IY62_RS13815	COG1238	metal cluster binding
IY62_RS13820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IY62_RS13845	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IY62_RS13865	COG1546	Belongs to the CinA family
IY62_RS13870	COG2951	lytic endotransglycosylase activity
IY62_RS13875	COG3730	PTS system glucitol sorbitol-specific
IY62_RS13880	COG3732	PTS system glucitol sorbitol-specific
IY62_RS13890	COG1028	Short-chain dehydrogenase reductase Sdr
IY62_RS13895	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS13905	COG1349	DNA-binding transcription factor activity
IY62_RS13910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IY62_RS13910	COG0517	IMP dehydrogenase activity
IY62_RS13930	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IY62_RS13935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IY62_RS13945	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IY62_RS13955	COG3260	NADH ubiquinone oxidoreductase 20
IY62_RS13960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IY62_RS13965	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IY62_RS13965	COG3261	NADH dehydrogenase
IY62_RS13970	COG0650	Formate hydrogenlyase subunit 4
IY62_RS13975	COG0651	ATP synthesis coupled electron transport
IY62_RS13980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IY62_RS13995	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IY62_RS14000	COG0298	carbon dioxide binding
IY62_RS14005	COG0409	Hydrogenase expression formation protein
IY62_RS14010	COG0309	Hydrogenase expression formation protein (HypE)
IY62_RS14030	COG1121	(ABC) transporter
IY62_RS14035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IY62_RS14040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IY62_RS14125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IY62_RS14215	COG2207	Transcriptional regulator
IY62_RS14270	COG0477	Major facilitator Superfamily
IY62_RS14280	COG2610	gluconate transmembrane transporter activity
IY62_RS14285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IY62_RS14290	COG3622	Belongs to the hyi family
IY62_RS14295	COG0235	Class ii aldolase
IY62_RS14305	COG2084	Dehydrogenase
IY62_RS14310	COG1349	DNA-binding transcription factor activity
IY62_RS14320	COG0163	prenyltransferase activity
IY62_RS14325	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IY62_RS14395	COG2234	aminopeptidase activity
IY62_RS14400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IY62_RS14405	COG1518	maintenance of DNA repeat elements
IY62_RS14420	COG1857	crispr-associated protein
IY62_RS14435	COG1203	CRISPR-associated helicase, Cas3
IY62_RS14460	COG0720	synthase
IY62_RS14465	COG0321	lipoyl(octanoyl) transferase activity
IY62_RS14465	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IY62_RS14470	COG0602	queuosine metabolic process
IY62_RS14485	COG3956	TIGRFAM MazG family protein
IY62_RS14490	COG3539	Fimbrial protein
IY62_RS14495	COG3188	usher protein
IY62_RS14500	COG3121	Chaperone
IY62_RS14505	COG3539	Fimbrial protein
IY62_RS14525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IY62_RS14535	COG4999	Histidine kinase
IY62_RS14535	COG3850	Histidine kinase
IY62_RS14535	COG2205	protein histidine kinase activity
IY62_RS14535	COG3437	response regulator, receiver
IY62_RS14540	COG1929	Belongs to the glycerate kinase type-1 family
IY62_RS14545	COG4948	Mandelate Racemase Muconate Lactonizing
IY62_RS14550	COG4948	Mandelate Racemase Muconate Lactonizing
IY62_RS14555	COG2271	Major facilitator Superfamily
IY62_RS14560	COG0716	FMN binding
IY62_RS14570	COG3098	single-species biofilm formation
IY62_RS14585	COG1611	Belongs to the LOG family
IY62_RS14590	COG0814	amino acid
IY62_RS14595	COG1760	l-serine dehydratase
IY62_RS14605	COG1454	alcohol dehydrogenase
IY62_RS14610	COG0235	Class ii aldolase
IY62_RS14615	COG0738	Major facilitator superfamily
IY62_RS14635	COG1349	DNA-binding transcription factor activity
IY62_RS14645	COG2363	Small membrane protein
IY62_RS14650	COG0583	DNA-binding transcription factor activity
IY62_RS14660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IY62_RS14665	COG2166	iron-sulfur cluster assembly
IY62_RS14670	COG2962	Rard protein
IY62_RS14675	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IY62_RS14680	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IY62_RS14695	COG0860	N-Acetylmuramoyl-L-alanine amidase
IY62_RS14705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IY62_RS14710	COG1074	ATP-dependent DNA helicase activity
IY62_RS14715	COG1025	Belongs to the peptidase M16 family
IY62_RS14720	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IY62_RS14725	COG4967	type IV pilus modification protein PilV
IY62_RS14735	COG4795	General secretion pathway protein
IY62_RS14740	COG2165	general secretion pathway protein
IY62_RS14780	COG0861	Integral membrane protein TerC family
IY62_RS14790	COG0667	Aldo Keto reductase
IY62_RS14810	COG1609	Transcriptional regulator
IY62_RS14820	COG0583	DNA-binding transcription factor activity
IY62_RS14825	COG1794	racemase activity, acting on amino acids and derivatives
IY62_RS14830	COG2814	Major facilitator Superfamily
IY62_RS14835	COG1028	Short-chain dehydrogenase reductase Sdr
IY62_RS14845	COG0183	Belongs to the thiolase family
IY62_RS14860	COG0814	amino acid
IY62_RS14895	COG3188	usher protein
IY62_RS14940	COG4942	peptidase
IY62_RS15000	COG1272	protein, Hemolysin III
IY62_RS15010	COG2723	6-phospho-beta-galactosidase activity
IY62_RS15035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IY62_RS15040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IY62_RS15045	COG0006	proline dipeptidase activity
IY62_RS15060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IY62_RS15065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IY62_RS15080	COG2968	Membrane
IY62_RS15090	COG0668	transmembrane transport
IY62_RS15095	COG0191	fructose-bisphosphate aldolase activity
IY62_RS15125	COG1122	ATPase activity
IY62_RS15130	COG1122	ATPase activity
IY62_RS15135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IY62_RS15140	COG0501	Belongs to the peptidase M48B family
IY62_RS15150	COG2267	carboxylic ester hydrolase activity
IY62_RS15155	COG2731	YhcH YjgK YiaL family protein
IY62_RS15160	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IY62_RS15165	COG1063	alcohol dehydrogenase
IY62_RS15170	COG0246	Mannitol dehydrogenase
IY62_RS15175	COG4948	Mandelate Racemase Muconate Lactonizing
IY62_RS15180	COG2186	Transcriptional regulator
IY62_RS15190	COG1166	arginine decarboxylase activity
IY62_RS15210	COG2814	Major facilitator Superfamily
IY62_RS15220	COG2356	endonuclease I
IY62_RS15225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IY62_RS15250	COG2805	Type II/IV secretion system protein
IY62_RS15255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IY62_RS15260	COG0762	integral membrane protein
IY62_RS15275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IY62_RS15285	COG0252	asparaginase activity
IY62_RS15295	COG3171	Protein conserved in bacteria
IY62_RS15325	COG1982	Orn Lys Arg decarboxylase major
IY62_RS15335	COG1811	Na channel or pump
IY62_RS15350	COG0427	acetyl-CoA hydrolase
IY62_RS15355	COG2030	dehydratase
IY62_RS15360	COG2301	Belongs to the HpcH HpaI aldolase family
IY62_RS15390	COG0531	amino acid
IY62_RS15400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IY62_RS15405	COG1012	belongs to the aldehyde dehydrogenase family
IY62_RS15430	COG2271	Major facilitator Superfamily
IY62_RS15440	COG0246	Mannitol dehydrogenase
IY62_RS15455	COG0754	glutathionylspermidine amidase activity
IY62_RS15460	COG0625	glutathione transferase activity
IY62_RS15470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IY62_RS15475	COG0298	carbon dioxide binding
IY62_RS15485	COG1773	rubredoxin
IY62_RS15490	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IY62_RS15495	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IY62_RS15500	COG5557	Pfam Polysulphide reductase, NrfD
IY62_RS15505	COG0437	4 iron, 4 sulfur cluster binding
IY62_RS15510	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IY62_RS15520	COG0840	transmembrane signaling receptor activity
IY62_RS15545	COG1028	Short-chain dehydrogenase reductase Sdr
IY62_RS15550	COG0848	biopolymer transport protein
IY62_RS15575	COG2207	Transcriptional regulator
IY62_RS15580	COG1979	alcohol dehydrogenase
IY62_RS15590	COG0471	metal ion transport
IY62_RS15640	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IY62_RS15645	COG3111	PFAM Bacterial OB fold (BOF) protein
IY62_RS15660	COG2249	NAD(P)H dehydrogenase (quinone) activity
IY62_RS15665	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IY62_RS15675	COG3150	esterase
IY62_RS15680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IY62_RS15685	COG3151	Protein conserved in bacteria
IY62_RS15690	COG0494	nUDIX hydrolase
IY62_RS15705	COG0754	glutathionylspermidine amidase activity
IY62_RS15710	COG3384	dioxygenase
IY62_RS15755	COG1585	Membrane protein implicated in regulation of membrane protease activity
IY62_RS15760	COG2268	Band 7 protein
IY62_RS15775	COG3025	triphosphatase activity
IY62_RS15780	COG4991	sh3 domain protein
IY62_RS15795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IY62_RS15815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IY62_RS15840	COG2375	cellular response to nickel ion
IY62_RS15845	COG1695	Transcriptional regulator
IY62_RS15850	COG0840	transmembrane signaling receptor activity
IY62_RS15855	COG0840	transmembrane signaling receptor activity
IY62_RS15865	COG0446	pyridine nucleotide-disulphide oxidoreductase
IY62_RS15865	COG1902	pentaerythritol trinitrate reductase activity
IY62_RS15875	COG1451	nucleotide metabolic process
IY62_RS15880	COG2949	membrane
IY62_RS15885	COG0673	inositol 2-dehydrogenase activity
IY62_RS15900	COG0586	Pfam SNARE associated Golgi protein
IY62_RS15910	COG1422	Protein of unknown function (DUF1090)
IY62_RS15915	COG4575	ribosome binding
IY62_RS15920	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IY62_RS15930	COG2259	Doxx family
IY62_RS15935	COG0435	Glutathione S-transferase
IY62_RS15940	COG3152	Membrane
IY62_RS15945	COG0583	DNA-binding transcription factor activity
IY62_RS15950	COG1741	Belongs to the pirin family
IY62_RS15965	COG0814	amino acid
IY62_RS15970	COG1760	l-serine dehydratase
IY62_RS15975	COG1882	Formate acetyltransferase
IY62_RS15995	COG0583	DNA-binding transcription factor activity
IY62_RS16000	COG1929	Belongs to the glycerate kinase type-1 family
IY62_RS16005	COG2084	Dehydrogenase
IY62_RS16015	COG2721	sulfolactate sulfo-lyase activity
IY62_RS16030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS16035	COG3414	Phosphotransferase system galactitol-specific IIB component
IY62_RS16040	COG3775	system Galactitol-specific IIC component
IY62_RS16045	COG1063	alcohol dehydrogenase
IY62_RS16055	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IY62_RS16060	COG3107	peptidoglycan biosynthetic process
IY62_RS16075	COG2823	Periplasmic or secreted lipoprotein
IY62_RS16080	COG0702	epimerase
IY62_RS16085	COG0693	protein deglycase activity
IY62_RS16100	COG3153	acetyltransferase
IY62_RS16105	COG3154	lipid carrier protein
IY62_RS16110	COG0826	peptidase U32
IY62_RS16115	COG0826	peptidase U32
IY62_RS16120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IY62_RS16125	COG3034	peptidoglycan biosynthetic process
IY62_RS16135	COG0814	amino acid
IY62_RS16140	COG0513	Belongs to the DEAD box helicase family
IY62_RS16205	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IY62_RS16215	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IY62_RS16230	COG1534	Rna-binding protein
IY62_RS16245	COG2027	D-alanyl-D-alanine carboxypeptidase
IY62_RS16255	COG0697	spore germination
IY62_RS16270	COG0142	geranyltranstransferase activity
IY62_RS16275	COG3423	Transcriptional regulator
IY62_RS16285	COG5007	Belongs to the BolA IbaG family
IY62_RS16290	COG3113	response to antibiotic
IY62_RS16295	COG2854	intermembrane phospholipid transfer
IY62_RS16300	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IY62_RS16305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IY62_RS16310	COG1127	ABC transporter
IY62_RS16315	COG0530	calcium, potassium:sodium antiporter activity
IY62_RS16325	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IY62_RS16330	COG3117	lipopolysaccharide transmembrane transporter activity
IY62_RS16335	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IY62_RS16340	COG1137	ATPase activity
IY62_RS16365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS16370	COG0515	serine threonine protein kinase
IY62_RS16380	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IY62_RS16385	COG2198	Histidine kinase
IY62_RS16385	COG0784	Response regulator, receiver
IY62_RS16385	COG5002	protein histidine kinase activity
IY62_RS16390	COG1242	4 iron, 4 sulfur cluster binding
IY62_RS16400	COG0069	glutamate synthase activity
IY62_RS16400	COG0070	glutamate synthase
IY62_RS16400	COG0067	glutamate synthase
IY62_RS16405	COG0493	'glutamate synthase
IY62_RS16410	COG4804	nuclease activity
IY62_RS16415	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IY62_RS16420	COG0402	S-adenosylhomocysteine deaminase activity
IY62_RS16425	COG2731	YhcH YjgK YiaL family protein
IY62_RS16455	COG2969	positive regulation of protein catabolic process
IY62_RS16460	COG0625	glutathione transferase activity
IY62_RS16480	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IY62_RS16485	COG3105	Protein conserved in bacteria
IY62_RS16490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IY62_RS16500	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IY62_RS16505	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IY62_RS16510	COG0511	ligase activity, forming carbon-carbon bonds
IY62_RS16510	COG5016	pyruvate
IY62_RS16520	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IY62_RS16525	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IY62_RS16530	COG0471	metal ion transport
IY62_RS16540	COG2188	Transcriptional regulator
IY62_RS16565	COG2732	(Barnase) inhibitor
IY62_RS16585	COG0583	DNA-binding transcription factor activity
IY62_RS16590	COG0312	modulator of DNA gyrase
IY62_RS16595	COG3164	Protein of unknown function
IY62_RS16610	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IY62_RS16615	COG1792	Involved in formation and maintenance of cell shape
IY62_RS16620	COG1077	Cell shape determining protein MreB Mrl
IY62_RS16630	COG2200	EAL domain
IY62_RS16630	COG2199	diguanylate cyclase activity
IY62_RS16635	COG0604	alcohol dehydrogenase
IY62_RS16650	COG0511	ligase activity, forming carbon-carbon bonds
IY62_RS16655	COG0439	Biotin carboxylase
IY62_RS16660	COG3924	membrane
IY62_RS16665	COG4145	pantothenate transmembrane transporter activity
IY62_RS16685	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IY62_RS16700	COG1309	transcriptional regulator
IY62_RS16705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IY62_RS16710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IY62_RS16750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IY62_RS16770	COG0551	DNA topoisomerase type I activity
IY62_RS16780	COG0758	DNA mediated transformation
IY62_RS16810	COG3036	rescue of stalled ribosome
IY62_RS16815	COG0789	Transcriptional regulator
IY62_RS16855	COG0201	protein transport
IY62_RS16935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IY62_RS16960	COG0051	transcription antitermination factor activity, RNA binding
IY62_RS17015	COG2964	Protein conserved in bacteria
IY62_RS17020	COG0545	Peptidyl-prolyl cis-trans isomerase
IY62_RS17030	COG1047	Peptidyl-prolyl cis-trans
IY62_RS17035	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IY62_RS17050	COG0488	(ABC) transporter
IY62_RS17065	COG0429	hydrolase of the alpha beta-hydrolase fold
IY62_RS17075	COG3954	Phosphoribulokinase
IY62_RS17080	COG1765	OsmC-like protein
IY62_RS17090	COG1289	transmembrane transporter activity
IY62_RS17125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IY62_RS17165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IY62_RS17170	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IY62_RS17175	COG3266	domain, Protein
IY62_RS17190	COG4796	Type ii and iii secretion system protein
IY62_RS17205	COG3166	PFAM Fimbrial assembly family protein
IY62_RS17210	COG4972	Pilus assembly protein
IY62_RS17215	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IY62_RS17220	COG0494	nUDIX hydrolase
IY62_RS17230	COG1011	Hydrolase
IY62_RS17235	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IY62_RS17245	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IY62_RS17265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IY62_RS17270	COG2183	response to ionizing radiation
IY62_RS17275	COG1918	ferrous iron import across plasma membrane
IY62_RS17290	COG5464	transposase or invertase
IY62_RS17310	COG2610	gluconate transmembrane transporter activity
IY62_RS17315	COG1640	4-alpha-glucanotransferase
IY62_RS17320	COG0058	SHG alpha-glucan phosphorylase activity
IY62_RS17330	COG3041	Addiction module toxin RelE StbE family
IY62_RS17335	COG3077	Addiction module antitoxin, RelB DinJ family
IY62_RS17345	COG1690	Belongs to the RtcB family
IY62_RS17355	COG4650	regulator
IY62_RS17360	COG1349	DNA-binding transcription factor activity
IY62_RS17375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IY62_RS17390	COG0371	Dehydrogenase
IY62_RS17400	COG0129	dihydroxy-acid dehydratase activity
IY62_RS17405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IY62_RS17410	COG1414	Transcriptional regulator
IY62_RS17415	COG0058	SHG alpha-glucan phosphorylase activity
IY62_RS17435	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IY62_RS17445	COG2610	gluconate transmembrane transporter activity
IY62_RS17450	COG3265	gluconokinase activity
IY62_RS17455	COG1609	Transcriptional regulator
IY62_RS17460	COG1741	Belongs to the pirin family
IY62_RS17465	COG0673	inositol 2-dehydrogenase activity
IY62_RS17470	COG1247	-acetyltransferase
IY62_RS17475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS17490	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IY62_RS17495	COG0405	Gamma-glutamyltransferase
IY62_RS17505	COG0584	glycerophosphoryl diester phosphodiesterase
IY62_RS17585	COG2177	Part of the ABC transporter FtsEX involved in
IY62_RS17590	COG2884	Cell division ATP-binding protein ftsE
IY62_RS17595	COG0552	protein localization to endoplasmic reticulum
IY62_RS17600	COG0742	ribosomal rna small subunit methyltransferase
IY62_RS17605	COG3776	membrane
IY62_RS17615	COG3714	YhhN family
IY62_RS17635	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IY62_RS17650	COG0628	permease
IY62_RS17655	COG2091	lysine biosynthetic process via aminoadipic acid
IY62_RS17665	COG0842	Transport permease protein
IY62_RS17670	COG1129	ABC transporter
IY62_RS17670	COG0842	Transport permease protein
IY62_RS17675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IY62_RS17680	COG2081	HI0933 family
IY62_RS17685	COG0306	phosphate transporter
IY62_RS17715	COG0671	phosphoesterase, PA-phosphatase related
IY62_RS17720	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IY62_RS17725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IY62_RS17735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IY62_RS17740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS17745	COG2222	sugar isomerase
IY62_RS17750	COG2188	Transcriptional regulator
IY62_RS17770	COG2197	response regulator
IY62_RS17775	COG0583	DNA-binding transcription factor activity
IY62_RS17780	COG1295	ribonuclease BN
IY62_RS17785	COG0477	Major facilitator Superfamily
IY62_RS17790	COG2982	Protein involved in outer membrane biogenesis
IY62_RS17795	COG2200	EAL domain
IY62_RS17800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS17815	COG2199	diguanylate cyclase activity
IY62_RS17815	COG2200	EAL domain
IY62_RS17825	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IY62_RS17870	COG2873	o-acetylhomoserine
IY62_RS17875	COG0814	amino acid
IY62_RS17880	COG4608	Belongs to the ABC transporter superfamily
IY62_RS17885	COG0444	Belongs to the ABC transporter superfamily
IY62_RS17890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IY62_RS17895	COG0601	transmembrane transport
IY62_RS17900	COG0747	negative chemotaxis
IY62_RS17915	COG1609	Transcriptional regulator
IY62_RS17965	COG5571	outer membrane autotransporter
IY62_RS17970	COG2818	Glycosylase
IY62_RS17975	COG0456	acetyltransferase
IY62_RS17980	COG0243	molybdopterin cofactor binding
IY62_RS17985	COG2885	chlorophyll binding
IY62_RS18000	COG2944	sequence-specific DNA binding
IY62_RS18005	COG1278	Cold shock
IY62_RS18050	COG3274	enterobacterial common antigen metabolic process
IY62_RS18055	COG4682	membrane
IY62_RS18060	COG1070	Carbohydrate kinase
IY62_RS18070	COG1609	Transcriptional regulator
IY62_RS18070	COG2207	Transcriptional regulator
IY62_RS18075	COG2992	FlgJ-related protein
IY62_RS18085	COG0366	Alpha amylase catalytic
IY62_RS18090	COG3977	Valine--pyruvate aminotransferase
IY62_RS18095	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IY62_RS18100	COG1414	Transcriptional regulator
IY62_RS18110	COG2731	YhcH YjgK YiaL family protein
IY62_RS18120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IY62_RS18125	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IY62_RS18130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IY62_RS18135	COG1070	Carbohydrate kinase
IY62_RS18140	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IY62_RS18145	COG3623	hexulose-6-phosphate isomerase
IY62_RS18150	COG0235	Class ii aldolase
IY62_RS18165	COG1012	belongs to the aldehyde dehydrogenase family
IY62_RS18170	COG1940	carbohydrate kinase activity
IY62_RS18175	COG3276	selenocysteine insertion sequence binding
IY62_RS18185	COG0625	glutathione transferase activity
IY62_RS18190	COG2213	PTS system mannitol-specific
IY62_RS18190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS18200	COG3722	fumarate hydratase activity
IY62_RS18230	COG2186	Transcriptional regulator
IY62_RS18240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IY62_RS18245	COG1609	Transcriptional regulator
IY62_RS18255	COG2271	Major facilitator Superfamily
IY62_RS18275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IY62_RS18280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IY62_RS18290	COG4942	peptidase
IY62_RS18295	COG2861	carbohydrate metabolic process
IY62_RS18300	COG1216	Glycosyl transferase, family 2
IY62_RS18375	COG0438	transferase activity, transferring glycosyl groups
IY62_RS18380	COG0859	PFAM glycosyl transferase family 9
IY62_RS18385	COG1519	Transferase
IY62_RS18415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IY62_RS18440	COG1561	YicC-like family, N-terminal region
IY62_RS18445	COG0583	DNA-binding transcription factor activity
IY62_RS18455	COG2860	membrane
IY62_RS18475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IY62_RS18480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IY62_RS18485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IY62_RS18490	COG0786	glutamate:sodium symporter activity
IY62_RS18495	COG2233	PERMEase
IY62_RS18500	COG2982	Protein involved in outer membrane biogenesis
IY62_RS18505	COG1501	Belongs to the glycosyl hydrolase 31 family
IY62_RS18510	COG2211	Major facilitator Superfamily
IY62_RS18540	COG2771	luxR family
IY62_RS18555	COG3710	Transcriptional regulator
IY62_RS18560	COG1335	isochorismatase
IY62_RS18585	COG5464	transposase or invertase
IY62_RS18600	COG3716	PTS system mannose fructose sorbose family IID component
IY62_RS18605	COG3715	PTS system
IY62_RS18610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS18610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IY62_RS18630	COG2723	6-phospho-beta-galactosidase activity
IY62_RS18680	COG0738	Major facilitator superfamily
IY62_RS18690	COG1349	DNA-binding transcription factor activity
IY62_RS18695	COG0440	acetolactate synthase activity
IY62_RS18700	COG0028	Belongs to the TPP enzyme family
IY62_RS18720	COG2814	Major facilitator Superfamily
IY62_RS18730	COG0583	DNA-binding transcription factor activity
IY62_RS18735	COG2610	gluconate transmembrane transporter activity
IY62_RS18745	COG0641	radical SAM
IY62_RS18755	COG2149	membrane
IY62_RS18775	COG5645	(Lipo)protein
IY62_RS18780	COG0823	Involved in the tonB-independent uptake of proteins
IY62_RS18785	COG3088	subunit of a heme lyase
IY62_RS18785	COG4235	cytochrome complex assembly
IY62_RS18795	COG1138	Cytochrome C-type biogenesis protein
IY62_RS18805	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IY62_RS18810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IY62_RS18815	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IY62_RS18820	COG4133	protoheme IX ABC transporter activity
IY62_RS18825	COG1858	cytochrome C peroxidase
IY62_RS18840	COG3005	denitrification pathway
IY62_RS18845	COG0745	RESPONSE REGULATOR receiver
IY62_RS18850	COG1879	ABC-type sugar transport system periplasmic component
IY62_RS18855	COG0784	Response regulator, receiver
IY62_RS18855	COG2205	protein histidine kinase activity
IY62_RS18855	COG2198	Histidine kinase
IY62_RS18860	COG2271	Major facilitator Superfamily
IY62_RS18870	COG0800	Aldolase
IY62_RS18875	COG3734	2-keto-3-deoxy-galactonokinase
IY62_RS18880	COG2186	Transcriptional regulator
IY62_RS18885	COG0561	phosphatase activity
IY62_RS18890	COG2271	Major facilitator Superfamily
IY62_RS18895	COG4948	Mandelate Racemase Muconate Lactonizing
IY62_RS18960	COG2091	lysine biosynthetic process via aminoadipic acid
IY62_RS18965	COG0431	NADPH-dependent FMN reductase
IY62_RS18970	COG2252	PERMEase
IY62_RS18975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IY62_RS18980	COG0704	Plays a role in the regulation of phosphate uptake
IY62_RS18990	COG0581	inorganic phosphate transmembrane transporter activity
IY62_RS18995	COG0573	inorganic phosphate transmembrane transporter activity
IY62_RS19000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IY62_RS19005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IY62_RS19005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IY62_RS19005	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IY62_RS19010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IY62_RS19015	COG4533	DNA binding
IY62_RS19075	COG3312	ion transport
IY62_RS19090	COG0716	FMN binding
IY62_RS19095	COG1522	sequence-specific DNA binding
IY62_RS19130	COG1172	Belongs to the binding-protein-dependent transport system permease family
IY62_RS19140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS19145	COG1609	Transcriptional regulator
IY62_RS19150	COG0477	Major facilitator Superfamily
IY62_RS19155	COG2186	Transcriptional regulator
IY62_RS19215	COG3978	acetolactate synthase activity
IY62_RS19280	COG3118	belongs to the thioredoxin family
IY62_RS19305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IY62_RS19310	COG1088	dTDP-glucose 4,6-dehydratase activity
IY62_RS19315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IY62_RS19315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IY62_RS19320	COG0456	acetyltransferase
IY62_RS19325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IY62_RS19330	COG2244	polysaccharide biosynthetic process
IY62_RS19375	COG3071	HemY protein
IY62_RS19380	COG2959	enzyme of heme biosynthesis
IY62_RS19435	COG1011	Hydrolase
IY62_RS19490	COG2267	carboxylic ester hydrolase activity
IY62_RS19495	COG0561	phosphatase activity
IY62_RS19515	COG0641	radical SAM
IY62_RS19560	COG0805	protein transport
IY62_RS19575	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IY62_RS19605	COG1739	Uncharacterized protein family UPF0029
IY62_RS19645	COG1763	Mo-molybdopterin cofactor biosynthetic process
IY62_RS19655	COG3084	Protein conserved in bacteria
IY62_RS19670	COG0204	Acyl-transferase
IY62_RS19725	COG0561	phosphatase activity
IY62_RS19770	COG1501	Belongs to the glycosyl hydrolase 31 family
IY62_RS19775	COG2017	converts alpha-aldose to the beta-anomer
IY62_RS19785	COG3684	Belongs to the aldolase LacD family
IY62_RS19795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS19800	COG1349	DNA-binding transcription factor activity
IY62_RS19805	COG1011	Hydrolase
IY62_RS19820	COG0456	acetyltransferase
IY62_RS19825	COG5499	transcription regulator containing HTH domain
IY62_RS19830	COG4680	protein conserved in bacteria
IY62_RS19840	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
IY62_RS19855	COG2864	formate dehydrogenase
IY62_RS19860	COG0437	4 iron, 4 sulfur cluster binding
IY62_RS19865	COG0243	molybdopterin cofactor binding
IY62_RS19865	COG3383	formate dehydrogenase (NAD+) activity
IY62_RS19870	COG0243	molybdopterin cofactor binding
IY62_RS19870	COG3383	formate dehydrogenase (NAD+) activity
IY62_RS19900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IY62_RS19915	COG1454	alcohol dehydrogenase
IY62_RS19970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IY62_RS19975	COG2258	MOSC domain
IY62_RS19990	COG2205	protein histidine kinase activity
IY62_RS19995	COG0745	RESPONSE REGULATOR receiver
IY62_RS20000	COG3678	ATP-independent chaperone mediated protein folding
IY62_RS20025	COG2211	Major facilitator Superfamily
IY62_RS20030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IY62_RS20040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IY62_RS20055	COG1070	Carbohydrate kinase
IY62_RS20080	COG1879	ABC-type sugar transport system periplasmic component
IY62_RS20110	COG3152	Membrane
IY62_RS20120	COG1494	fructose-1,6-bisphosphatase
IY62_RS20130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IY62_RS20145	COG1575	Belongs to the MenA family. Type 1 subfamily
IY62_RS20160	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IY62_RS20165	COG1609	Transcriptional regulator
IY62_RS20170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IY62_RS20195	COG0626	cystathionine gamma-synthase activity
IY62_RS20200	COG0460	homoserine dehydrogenase
IY62_RS20200	COG0527	aspartate kinase activity
IY62_RS20205	COG0668	transmembrane transport
IY62_RS20220	COG0737	Belongs to the 5'-nucleotidase family
IY62_RS20225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IY62_RS20230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IY62_RS20255	COG3738	Protein conserved in bacteria
IY62_RS20260	COG0371	Dehydrogenase
IY62_RS20270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS20270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS20270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IY62_RS20275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IY62_RS20280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IY62_RS20285	COG1882	Formate acetyltransferase
IY62_RS20290	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IY62_RS20295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IY62_RS20300	COG2207	Transcriptional regulator
IY62_RS20335	COG0583	DNA-binding transcription factor activity
IY62_RS20445	COG0250	Participates in transcription elongation, termination and antitermination
IY62_RS20510	COG2104	thiamine diphosphate biosynthetic process
IY62_RS20515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IY62_RS20620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IY62_RS20665	COG3122	Protein conserved in bacteria
IY62_RS20680	COG1349	DNA-binding transcription factor activity
IY62_RS20685	COG0561	phosphatase activity
IY62_RS20720	COG0527	aspartate kinase activity
IY62_RS20745	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IY62_RS20800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IY62_RS20810	COG0534	Mate efflux family protein
IY62_RS20825	COG0735	belongs to the Fur family
IY62_RS20875	COG2315	Protein conserved in bacteria
IY62_RS20940	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IY62_RS20960	COG2252	PERMEase
IY62_RS20965	COG0025	NhaP-type Na H and K H
IY62_RS20970	COG0583	DNA-binding transcription factor activity
IY62_RS20975	COG1380	Effector of murein hydrolase LrgA
IY62_RS20980	COG1346	cytolysis
IY62_RS20990	COG3162	membrane
IY62_RS20995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IY62_RS21010	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IY62_RS21015	COG0437	4 iron, 4 sulfur cluster binding
IY62_RS21020	COG3301	Polysulphide reductase, NrfD
IY62_RS21025	COG1138	Cytochrome C-type biogenesis protein
IY62_RS21030	COG3088	subunit of a heme lyase
IY62_RS21035	COG4235	cytochrome complex assembly
IY62_RS21040	COG1301	dicarboxylic acid transport
IY62_RS21045	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IY62_RS21070	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IY62_RS21075	COG2824	Alkylphosphonate utilization operon protein PhnA
IY62_RS21105	COG0531	amino acid
IY62_RS21110	COG2207	Transcriptional regulator
IY62_RS21120	COG1982	Orn Lys Arg decarboxylase major
IY62_RS21125	COG2169	Transcriptional regulator
IY62_RS21140	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IY62_RS21140	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IY62_RS21145	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IY62_RS21155	COG4565	transcriptional regulatory protein
IY62_RS21160	COG3290	protein histidine kinase activity
IY62_RS21165	COG0243	molybdopterin cofactor binding
IY62_RS21170	COG0437	4 iron, 4 sulfur cluster binding
IY62_RS21175	COG3302	dmso reductase anchor subunit
IY62_RS21180	COG3381	protein complex oligomerization
IY62_RS21200	COG2197	response regulator
IY62_RS21240	COG1309	transcriptional regulator
IY62_RS21255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IY62_RS21260	COG1027	Aspartate ammonia-lyase
IY62_RS21270	COG3030	protein affecting phage T7 exclusion by the F plasmid
IY62_RS21275	COG0531	amino acid
IY62_RS21315	COG5510	response to toxic substance
IY62_RS21345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IY62_RS21350	COG1053	succinate dehydrogenase
IY62_RS21370	COG3264	Mechanosensitive ion channel
IY62_RS21370	COG1511	domain protein
IY62_RS21390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IY62_RS21410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IY62_RS21410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IY62_RS21415	COG0802	atpase or kinase
IY62_RS21440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IY62_RS21445	COG0330	HflC and HflK could
IY62_RS21450	COG0330	HflC and HflK could
IY62_RS21455	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IY62_RS21470	COG0557	exoribonuclease II activity
IY62_RS21480	COG3789	protein conserved in bacteria
IY62_RS21485	COG1842	Phage shock protein A
IY62_RS21500	COG3766	membrane
IY62_RS21505	COG5463	Belongs to the UPF0441 family
IY62_RS21510	COG0754	glutathionylspermidine amidase activity
IY62_RS21515	COG1960	acyl-CoA dehydrogenase activity
IY62_RS21525	COG3650	response to hydrogen peroxide
IY62_RS21530	COG1073	alpha beta
IY62_RS21550	COG3414	Phosphotransferase system galactitol-specific IIB component
IY62_RS21595	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IY62_RS21610	COG3061	Opacity-associated protein A
IY62_RS21615	COG0545	Peptidyl-prolyl cis-trans isomerase
IY62_RS21620	COG1113	amino acid transport
IY62_RS21640	COG0697	spore germination
IY62_RS21645	COG0702	epimerase
IY62_RS21650	COG1733	regulation of RNA biosynthetic process
IY62_RS21665	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IY62_RS21675	COG1253	flavin adenine dinucleotide binding
IY62_RS21695	COG2105	PFAM AIG2 family protein
IY62_RS21700	COG2271	Major facilitator Superfamily
IY62_RS21705	COG3964	amidohydrolase
IY62_RS21720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IY62_RS21730	COG0312	modulator of DNA gyrase
IY62_RS21765	COG3964	amidohydrolase
IY62_RS21780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IY62_RS21780	COG3711	transcriptional antiterminator
IY62_RS21785	COG3077	Addiction module antitoxin, RelB DinJ family
IY62_RS21790	COG2026	Addiction module toxin, RelE StbE family
IY62_RS21810	COG0366	Alpha amylase catalytic
IY62_RS21815	COG1263	PTS System
IY62_RS21815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IY62_RS21855	COG1438	arginine binding
IY62_RS21860	COG1288	antiporter activity
IY62_RS21880	COG2731	YhcH YjgK YiaL family protein
IY62_RS21925	COG2927	DNA polymerase III (CHI subunit)
IY62_RS21940	COG0795	lipopolysaccharide-transporting ATPase activity
IY62_RS21945	COG0795	lipopolysaccharide-transporting ATPase activity
IY62_RS21950	COG1609	Transcriptional regulator
IY62_RS21955	COG2610	gluconate transmembrane transporter activity
IY62_RS21960	COG1028	Short-chain dehydrogenase reductase Sdr
IY62_RS21965	COG1063	alcohol dehydrogenase
IY62_RS21970	COG3265	gluconokinase activity
IY62_RS21975	COG1064	alcohol dehydrogenase
IY62_RS22050	COG3204	pilus organization
IY62_RS22055	COG2963	transposase activity
IY62_RS22080	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IY62_RS22110	COG0412	Dienelactone hydrolase
IY62_RS22115	COG2186	Transcriptional regulator
IY62_RS22140	COG0583	DNA-binding transcription factor activity
IY62_RS22145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IY62_RS22150	COG0700	Nucleoside recognition
IY62_RS22155	COG3366	ferrous iron transmembrane transporter activity
IY62_RS22165	COG0477	Major facilitator Superfamily
IY62_RS22170	COG2733	membrane
IY62_RS22180	COG5464	transposase or invertase
IY62_RS22185	COG1012	belongs to the aldehyde dehydrogenase family
IY62_RS22200	COG3586	endonuclease activity
IY62_RS22205	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IY62_RS22210	COG0732	type I restriction modification DNA specificity domain
IY62_RS22215	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IY62_RS22265	COG0523	cobalamin synthesis protein
IY62_RS22270	COG2879	small protein
IY62_RS22275	COG1966	Carbon starvation protein
IY62_RS22280	COG0840	transmembrane signaling receptor activity
IY62_RS22295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IY62_RS22300	COG3715	PTS system
IY62_RS22305	COG3716	PTS system mannose fructose sorbose family IID component
IY62_RS22310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IY62_RS22330	COG1484	DNA-dependent DNA replication
IY62_RS22345	COG2966	Psort location CytoplasmicMembrane, score
IY62_RS22350	COG2197	response regulator
IY62_RS22355	COG2197	response regulator
IY62_RS22360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IY62_RS22365	COG4114	ferric iron reductase
IY62_RS22370	COG3706	GGDEF domain
IY62_RS22400	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IY62_RS22410	COG1011	Hydrolase
IY62_RS22420	COG2823	Periplasmic or secreted lipoprotein
IY62_RS22430	COG4667	esterase of the alpha-beta hydrolase superfamily
IY62_RS22435	COG0084	hydrolase, TatD family'
IY62_RS22440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IY62_RS22445	COG1328	CTP reductase activity
IY62_RS22470	COG3550	peptidyl-serine autophosphorylation
IY62_RS22480	COG3726	membrane protein affecting hemolysin expression
IY62_RS22485	COG0560	Phosphoserine phosphatase
IY62_RS22500	COG0488	(ABC) transporter
IY62_RS22525	COG2207	Transcriptional regulator
IY62_RS22525	COG3708	Transcriptional regulator
IY62_RS22530	COG3045	CreA protein
IY62_RS22535	COG0745	RESPONSE REGULATOR receiver
IY62_RS22540	COG2205	protein histidine kinase activity
IY62_RS22545	COG4452	Inner membrane protein CreD
IY62_RS22565	COG3121	Chaperone
IY62_RS22585	COG0745	RESPONSE REGULATOR receiver
IY62_RS22595	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IY62_RS22640	COG0582	viral genome integration into host DNA
IY62_RS22790	COG0582	viral genome integration into host DNA
IY62_RS22910	COG1119	ATPase activity
IY62_RS23010	COG3209	COG3209 Rhs family protein
IY62_RS23350	COG1666	GTP binding
IY62_RS23465	COG3328	transposase activity
IY62_RS23715	COG4948	Mandelate Racemase Muconate Lactonizing
IY62_RS23755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IY62_RS23865	COG2963	transposase activity
IY62_RS23885	COG0477	Major facilitator Superfamily
IY62_RS23895	COG3201	nicotinamide mononucleotide transporter
IY62_RS23930	COG2134	cdp-diacylglycerol pyrophosphatase
IY62_RS23970	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
IY62_RS23980	COG1113	amino acid transport