locus-tag class description HEC95_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HEC95_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HEC95_RS00030 ENOG4105CXK mandelate racemase muconate lactonizing HEC95_RS00035 ENOG4105DJB Major Facilitator Superfamily HEC95_RS00040 ENOG410667J hydrolase HEC95_RS00045 ENOG4105EMF GntR family transcriptional regulator HEC95_RS00050 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HEC95_RS00055 ENOG4108RTU Aldolase HEC95_RS00065 ENOG4105DJB Major Facilitator Superfamily HEC95_RS00070 ENOG4105BZU Histidine kinase HEC95_RS00075 ENOG4108SV3 Tmao reductase system periplasmic protein tort HEC95_RS00080 ENOG4106WF9 DNA-binding transcriptional regulator TorR HEC95_RS00085 ENOG4105CUW cytochrome C-TYPE protein HEC95_RS00090 ENOG4108EM1 reductase HEC95_RS00100 ENOG4105CA0 peroxidase HEC95_RS00105 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HEC95_RS00110 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HEC95_RS00115 ENOG41060IM Heme exporter protein HEC95_RS00120 ENOG4105X3C heme exporter protein HEC95_RS00130 ENOG4105DA4 cytochrome c-type biogenesis protein HEC95_RS00135 ENOG4107QX9 Thiol disulfide interChange protein HEC95_RS00140 ENOG4105KWW Biogenesis protein HEC95_RS00145 ENOG4105D99 atp gtp-binding protein HEC95_RS00150 ENOG4105R2A (LipO)protein HEC95_RS00170 ENOG4105VG5 Membrane HEC95_RS00175 ENOG4105JP4 Inner membrane protein yidG HEC95_RS00180 ENOG4105J13 transcriptional regulator HEC95_RS00195 ENOG4105W8I Transcriptional regulator HEC95_RS00205 ENOG4105E5M Multidrug resistance protein D HEC95_RS00230 ENOG4105C7K acetolactate synthase HEC95_RS00235 ENOG4105M71 acetolactate synthase 1 regulatory subunit HEC95_RS00240 ENOG4107FB0 transcriptional regulator DeoR family HEC95_RS00250 ENOG4105EDR glucose galactose transporter HEC95_RS00260 ENOG4108KX4 response regulator HEC95_RS00265 ENOG4105BZU Histidine kinase HEC95_RS00270 ENOG4105CXY transporter HEC95_RS00275 ENOG4105CXY transporter HEC95_RS00280 ENOG4108SAJ Protein of unknown function (DUF1198) HEC95_RS00300 ENOG4105CS2 ec 3.2.1.21 HEC95_RS00320 ENOG4105DAS pts system HEC95_RS00325 ENOG4105ETZ PTS System HEC95_RS00330 ENOG4105F3R pts system mannose fructose sorbose family iid HEC95_RS00345 ENOG4105DNE Transposase HEC95_RS00350 ENOG4108UZ3 Transporter HEC95_RS00360 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HEC95_RS00375 ENOG4105CHJ isochorismatase hydrolase HEC95_RS00385 ENOG4108TC1 Transcriptional regulator HEC95_RS00390 ENOG4105FV3 HEC95_RS00400 ENOG4105ISV protein with bipartite regulator domain HEC95_RS00445 ENOG4105CT4 transporter HEC95_RS00450 ENOG4105CJQ hydrolase, family 31 HEC95_RS00455 ENOG4105JV1 AsmA family HEC95_RS00460 ENOG4105C2W permease HEC95_RS00465 ENOG4105D6U Sodium Glutamate Symporter HEC95_RS00470 ENOG4105CB5 ATP-dependent DNA helicase recG HEC95_RS00475 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HEC95_RS00480 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HEC95_RS00500 ENOG4105EN6 Membrane HEC95_RS00515 ENOG4105DSJ YicC domain protein HEC95_RS00520 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) HEC95_RS00540 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HEC95_RS00570 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HEC95_RS00575 ENOG4105DKP glycosyl transferase, family 9 HEC95_RS00580 ENOG4107RJ7 Glycosyl transferase (Group 1 HEC95_RS00585 ENOG4107543 (lipo)polysaccharide HEC95_RS00595 ENOG4107XU6 Glycosyl transferase (Group 1 HEC95_RS00600 ENOG4106AH0 Glycosyl Transferase HEC95_RS00605 ENOG4105X1N Glycosyl transferase family 8 HEC95_RS00610 ENOG4108PDR lipopolysaccharide core biosynthesis protein HEC95_RS00615 ENOG4108QD8 lipopolysaccharide core biosynthesis protein HEC95_RS00620 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase HEC95_RS00625 ENOG4108FRV O-antigen ligase HEC95_RS00630 ENOG4105D16 lipopolysaccharide heptosyltransferase i HEC95_RS00635 ENOG4105XA0 heptosyltransferase ii HEC95_RS00645 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HEC95_RS00655 ENOG4105K64 Glycosyl transferase, family 2 HEC95_RS00660 ENOG4105PXI polysaccharide deacetylase HEC95_RS00665 ENOG41063SB peptidase HEC95_RS00675 ENOG4107YZP Rhodanese domain protein HEC95_RS00680 ENOG4105VW4 glutaredoxin 3 HEC95_RS00685 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) HEC95_RS00690 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase HEC95_RS00695 ENOG4105D7W serine acetyltransferase HEC95_RS00700 ENOG4105DJB Major Facilitator Superfamily HEC95_RS00705 ENOG4105DIA mandelate racemase muconate lactonizing HEC95_RS00710 ENOG4105ETE Transcriptional regulator (LacI family HEC95_RS00715 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HEC95_RS00725 ENOG41073TP transcriptional regulator HEC95_RS00730 ENOG4105DAA L-lactate HEC95_RS00735 ENOG4105EUR Domain-Containing protein HEC95_RS00740 ENOG4108WY4 inner membrane lipoprotein HEC95_RS00745 ENOG4108YYI Protein of unknown function (DUF2810) HEC95_RS00755 ENOG4105E61 Mannitol repressor protein HEC95_RS00765 ENOG4105CTS PTS system mannitol-specific HEC95_RS00770 ENOG4108U78 Glutathione S-transferase HEC95_RS00780 ENOG4105EM7 Selenocysteine-specific translation elongation factor HEC95_RS00785 ENOG41066F8 ROK family HEC95_RS00790 ENOG4105C26 Dehydrogenase HEC95_RS00805 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HEC95_RS00810 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HEC95_RS00815 ENOG4105H6Q decarboxylase HEC95_RS00820 ENOG4105CMG Carbohydrate kinase HEC95_RS00825 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HEC95_RS00830 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HEC95_RS00835 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HEC95_RS00840 ENOG4108M5W HEC95_RS00845 ENOG4108R66 Conserved Protein HEC95_RS00855 ENOG4105J4Q Transcriptional regulator HEC95_RS00860 ENOG4108XIB electron transport protein ysaA HEC95_RS00865 ENOG4105JKW Valine--pyruvate aminotransferase HEC95_RS00870 ENOG4107T9C Alpha amylase catalytic region HEC95_RS00875 ENOG4108UR8 BAX protein HEC95_RS00880 ENOG4105T16 Transcriptional regulator (AraC family) HEC95_RS00890 ENOG4105CMG Carbohydrate kinase HEC95_RS00895 ENOG410688U Inner membrane protein yiaB HEC95_RS00900 ENOG4105MEV Acyl-transferase HEC95_RS00905 ENOG4105RGS lipoprotein ysaB HEC95_RS00920 ENOG4105DQ6 Transposase HEC95_RS00950 ENOG4105MVF Transcriptional regulator HEC95_RS00955 ENOG4106JH6 (LipO)protein HEC95_RS00965 ENOG4108ZG0 Ompa motb domain protein HEC95_RS00970 ENOG4107QY8 reductase HEC95_RS00975 ENOG4105HNP -acetyltransferase HEC95_RS00980 ENOG4108R3E Dna-3-methyladenine glycosylase i HEC95_RS00985 ENOG4105EAX Putative lipase HEC95_RS00990 ENOG4106EAR Fimbrial protein HEC95_RS00995 ENOG4108VCD Chaperone HEC95_RS01000 ENOG4105CW0 outer membrane usher protein HEC95_RS01005 ENOG4105MHR Fimbrial protein HEC95_RS01010 ENOG4106UCC Fimbrial protein HEC95_RS01015 ENOG4105DIJ Phosphoethanolamine transferase HEC95_RS01035 ENOG4105CQ4 Transcriptional regulator HEC95_RS01050 ENOG4105DEF Extracellular solute-binding protein, family 5 HEC95_RS01055 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HEC95_RS01060 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HEC95_RS01065 ENOG4105C3U ABC transporter HEC95_RS01070 ENOG4108JQ7 (ABC) transporter HEC95_RS01075 ENOG4105C44 Serine transporter HEC95_RS01090 ENOG4105D1V cellulose synthase operon protein YhjU HEC95_RS01095 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT HEC95_RS01105 ENOG410661M cytoplasmic protein HEC95_RS01110 ENOG4105UTS cellulose synthase operon protein YhjQ HEC95_RS01115 ENOG4107QZ7 Cellulose synthase catalytic subunit HEC95_RS01120 ENOG4107EEX Cellulose synthase regulator protein HEC95_RS01125 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HEC95_RS01130 ENOG4105EJG cellulose synthase HEC95_RS01135 ENOG4105BZU Histidine kinase HEC95_RS01145 ENOG4105CS0 peptidase HEC95_RS01150 ENOG4107SS6 2-dehydro-3-deoxygluconokinase HEC95_RS01155 ENOG4105CMB EAL domain-containing protein HEC95_RS01160 ENOG41066T0 asmA family HEC95_RS01165 ENOG4105CSH Transporter HEC95_RS01170 ENOG4107H3J ribonuclease HEC95_RS01175 ENOG4105CBN LysR family transcriptional regulator HEC95_RS01180 ENOG4106S2D Transcriptional regulator HEC95_RS01200 ENOG4105FDP GntR family transcriptional regulator HEC95_RS01205 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine HEC95_RS01210 ENOG4108KPW sugar kinase HEC95_RS01215 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HEC95_RS01225 ENOG4105DC8 reductase HEC95_RS01230 ENOG4105D6S protein involved in catabolism of external DNA HEC95_RS01235 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HEC95_RS01240 ENOG4105DGW oligopeptidase A HEC95_RS01250 ENOG4105DUX Transporter HEC95_RS01255 ENOG4108M6U Universal stress protein A HEC95_RS01265 ENOG4105CJ3 phosphate transporter HEC95_RS01270 ENOG4105CBX hi0933 family HEC95_RS01275 ENOG4105D0S secretion protein (HlyD HEC95_RS01280 ENOG4105CJ1 ABC, transporter HEC95_RS01285 ENOG4105CMI transporter HEC95_RS01295 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HEC95_RS01300 ENOG4105DSF transport protein HEC95_RS01310 ENOG4108W1V Lipoprotein HEC95_RS01315 ENOG4105EX9 Membrane HEC95_RS01325 ENOG4105C8Q Methyl-accepting chemotaxis HEC95_RS01335 ENOG4107FS9 Membrane HEC95_RS01345 ENOG4105MG3 Membrane HEC95_RS01350 ENOG4106H78 methyltransferase HEC95_RS01355 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HEC95_RS01360 ENOG4105CAK Cell division ATP-binding protein ftsE HEC95_RS01365 ENOG4105CRP Part of the ABC transporter FtsEX involved in HEC95_RS01375 ENOG4105CP9 extracellular ligand-binding receptor HEC95_RS01385 ENOG4105U59 -acetyltransferase HEC95_RS01390 ENOG4105CP9 extracellular ligand-binding receptor HEC95_RS01395 ENOG4105C32 Amino acid ABC transporter (Permease) HEC95_RS01400 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HEC95_RS01405 ENOG4105C0Z ABC transporter HEC95_RS01410 ENOG4108IV0 ABC, transporter HEC95_RS01415 ENOG41060M8 Pfam:PhdYeFM HEC95_RS01425 ENOG4105BZ7 extracellular solute-binding protein family 1 HEC95_RS01430 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component HEC95_RS01445 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HEC95_RS01450 ENOG4105WC8 Conserved Protein HEC95_RS01455 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HEC95_RS01460 ENOG41080QX K07048 phosphotriesterase-related protein HEC95_RS01475 ENOG4108RVA ribokinase HEC95_RS01480 ENOG4105WCN acetyltransferase HEC95_RS01485 ENOG4105D9R oxidoreductase HEC95_RS01490 ENOG4105C2I pirin domain protein HEC95_RS01495 ENOG4105DIQ Transcriptional regulator HEC95_RS01500 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HEC95_RS01505 ENOG4105C6Z Gluconate HEC95_RS01515 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HEC95_RS01520 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) HEC95_RS01540 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HEC95_RS01545 ENOG4107HP6 Transcriptional regulator HEC95_RS01550 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HEC95_RS01555 ENOG4105C01 Dihydroxy-acid dehydratase HEC95_RS01565 ENOG4105DCT glycerol dehydrogenase HEC95_RS01580 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HEC95_RS01595 ENOG4105E98 transcriptional regulator DeoR family HEC95_RS01600 ENOG4105CYB regulatoR HEC95_RS01610 ENOG4105E0Y RtcB Protein HEC95_RS01625 ENOG4105VXN addiction module toxin, RelE StbE family HEC95_RS01635 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HEC95_RS01640 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HEC95_RS01645 ENOG4105C6Z Gluconate HEC95_RS01655 ENOG4105MJ2 Competence protein HEC95_RS01665 ENOG4105DNE Transposase HEC95_RS01680 ENOG4105XFK Ferrous iron transport protein A HEC95_RS01685 ENOG4105BZM domain protein HEC95_RS01690 ENOG4108RRZ Transcription elongation factor GreB HEC95_RS01700 ENOG4105E0F Histidine kinase HEC95_RS01710 ENOG4108MAJ Membrane HEC95_RS01720 ENOG4105VEJ Heat shock protein HEC95_RS01725 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HEC95_RS01735 ENOG4107RK2 ADP-ribose diphosphatase NudE HEC95_RS01740 ENOG4108JQC penicillin-binding protein 1A HEC95_RS01745 ENOG4108U1Q Pilus assembly protein HEC95_RS01750 ENOG41065NF Fimbrial assembly family protein HEC95_RS01755 ENOG4105XPX DNA utilization protein HofO HEC95_RS01760 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HEC95_RS01765 ENOG4105E4G Type IV pilus HEC95_RS01780 ENOG4105EGB membrane protein DamX HEC95_RS01785 ENOG4105DFE Dna adenine methylase HEC95_RS01790 ENOG4105DJV ribulose-phosphate 3-epimerase HEC95_RS01800 ENOG4105C31 Tryptophanyl-tRNA synthetase HEC95_RS01805 ENOG4105VYH HEC95_RS01810 ENOG4107EF2 surface-exposed virulence protein HEC95_RS01820 ENOG4107V9H nitrite transporter HEC95_RS01825 ENOG4105WZK nitrite reductase NADPH small subunit HEC95_RS01830 ENOG4107QZF nitrite reductase NADPH large subunit HEC95_RS01840 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HEC95_RS01845 ENOG4106195 uncharacterized protein yhfG HEC95_RS01850 ENOG4105MZU cell filamentation protein HEC95_RS01855 ENOG4105DDQ anthranilate synthase HEC95_RS01860 ENOG4105C8Y Acetylornithine aminotransferase HEC95_RS01865 ENOG410613R integral membrane protein, YccS YhfK family HEC95_RS01870 ENOG4107RYR Transcriptional regulator, Crp Fnr family HEC95_RS01875 ENOG4108UKZ OsmC family HEC95_RS01880 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HEC95_RS01890 ENOG4105DNZ Alpha Beta Hydrolase HEC95_RS01895 ENOG4105N0V mono-oxygenase ydhR HEC95_RS01900 ENOG4108K70 Transcriptional regulator HEC95_RS01905 ENOG4105C5H ABC transporter HEC95_RS01920 ENOG4105VKU nucleicacid-binding protein HEC95_RS01925 ENOG4108YZY peptidylprolyl cis-trans isomerase HEC95_RS01930 ENOG4105VRX Protein slyX homolog HEC95_RS01935 ENOG4108V1T peptidylprolyl cis-trans isomerase HEC95_RS01940 ENOG4105WWK YheO domain protein HEC95_RS01975 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) HEC95_RS01980 ENOG4105W53 bacterioferritin-associated ferredoxin HEC95_RS01985 ENOG4108UQY Iron-storage protein HEC95_RS01990 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) HEC95_RS02020 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) HEC95_RS02040 ENOG41083MP 50s ribosomal protein l29 HEC95_RS02045 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal HEC95_RS02055 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) HEC95_RS02080 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) HEC95_RS02090 ENOG4105VPB 50S ribosomal protein L30 HEC95_RS02100 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HEC95_RS02105 ENOG41067V7 50S ribosomal protein L36 HEC95_RS02120 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) HEC95_RS02135 ENOG4105VTS DnaJ-like, subfamily C HEC95_RS02140 ENOG4105W1Y Transcriptional regulator HEC95_RS02145 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HEC95_RS02150 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) HEC95_RS02155 ENOG4105C1A potassium transporter peripheral membrane HEC95_RS02175 ENOG4105C79 DNA protecting protein DprA HEC95_RS02185 ENOG4108WI1 Dna topoisomerase HEC95_RS02200 ENOG4105SG3 Protein of unknown function (DUF1488) HEC95_RS02205 ENOG4108Z0R Transferase HEC95_RS02235 ENOG4105K5X acetyltransferase HEC95_RS02245 ENOG4107QP3 malate synthase g HEC95_RS02250 ENOG4108I9X Isocitrate lyase HEC95_RS02265 ENOG41069M3 Transcriptional regulator HEC95_RS02270 ENOG4105C3R Methionine synthase HEC95_RS02275 ENOG4105EAM Na Pi-cotransporter HEC95_RS02290 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HEC95_RS02295 ENOG4105FE9 pseudouridine synthase HEC95_RS02300 ENOG4108ZR5 Conserved Protein HEC95_RS02305 ENOG4105E98 transcriptional regulator DeoR family HEC95_RS02310 ENOG4108KP7 hydrolase HEC95_RS02340 ENOG4105CFH Aspartokinase HEC95_RS02355 ENOG4108MDC (LipO)protein HEC95_RS02360 ENOG4108Q9C Periplasmic Protein HEC95_RS02365 ENOG4105E3R (LipO)protein HEC95_RS02375 ENOG4105EG2 ABC transporter, permease HEC95_RS02380 ENOG4105D56 permease protein HEC95_RS02385 ENOG4107FKK extracellular solute-binding protein family 1 HEC95_RS02390 ENOG4108IJ9 (ABC) transporter HEC95_RS02400 ENOG4107W52 maltose operon periplasmic protein HEC95_RS02420 ENOG41080IJ Diacylglycerol kinase HEC95_RS02425 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) HEC95_RS02430 ENOG4107R73 Mate efflux family protein HEC95_RS02440 ENOG4105VDW Csbd family HEC95_RS02445 ENOG4105MYN Zinc uptake regulation protein HEC95_RS02455 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HEC95_RS02460 ENOG4105P4Z Phage shock protein G HEC95_RS02465 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HEC95_RS02470 ENOG4105CDU Replicative dna helicase HEC95_RS02475 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HEC95_RS02480 ENOG4105CGF Aromatic amino acid aminotransferase HEC95_RS02485 ENOG4105F0S class B acid phosphatase HEC95_RS02490 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HEC95_RS02495 ENOG4105MSB protein, conserved in bacteria HEC95_RS02510 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HEC95_RS02515 ENOG4108UUM single-stranded DNA-binding protein HEC95_RS02550 ENOG4105PMV Membrane HEC95_RS02555 ENOG4108M8H domain protein HEC95_RS02560 ENOG4108W3Q Transcriptional regulator HEC95_RS02565 ENOG4108Z4X TRANSCRIPTIONal HEC95_RS02575 ENOG4105C7N Xanthine uracil vitamin C permease HEC95_RS02580 ENOG4105EEQ Na H antiporter HEC95_RS02585 ENOG4105CMU LysR family (Transcriptional regulator HEC95_RS02595 ENOG41067MG lrgb family HEC95_RS02600 ENOG4107QN1 sodium solute HEC95_RS02605 ENOG41062QD Membrane HEC95_RS02610 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HEC95_RS02620 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HEC95_RS02625 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HEC95_RS02630 ENOG4105DVI reductase, NrfD HEC95_RS02635 ENOG4108QKW cytochrome c-type biogenesis protein HEC95_RS02645 ENOG4108W0S formate-dependent nitrite reductase complex HEC95_RS02650 ENOG4105CK2 sodium dicarboxylate symporter HEC95_RS02655 ENOG41082ND Uncharacterized protein yjcO HEC95_RS02670 ENOG410870W N-acetyltransferase HEC95_RS02675 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HEC95_RS02680 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HEC95_RS02685 ENOG4105CSH Transporter HEC95_RS02695 ENOG4105ECM Sensor protein basS pmrB HEC95_RS02700 ENOG4105XJC Two component transcriptional regulator (Winged helix family HEC95_RS02705 ENOG4105DIJ Phosphoethanolamine transferase HEC95_RS02710 ENOG4105D5Q Arginine ornithine antiporter HEC95_RS02715 ENOG4106ZGR Transcriptional regulator HEC95_RS02720 ENOG4105CXN decarboxylase HEC95_RS02725 ENOG4108K2B transcriptional regulator HEC95_RS02730 ENOG4105F8D glycoside hydrolase family 4 HEC95_RS02735 ENOG4105CT4 transporter HEC95_RS02740 ENOG4107GFK fumarate HEC95_RS02745 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HEC95_RS02755 ENOG4108MRH transcriptional regulatory protein HEC95_RS02760 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HEC95_RS02770 ENOG4105QAX Iron-sulfur HEC95_RS02775 ENOG4107KGK dmso reductase anchor subunit HEC95_RS02780 ENOG4108NEM leader-binding protein dmsD HEC95_RS02790 ENOG4108ZK4 sdia-regulated domain-containing protein HEC95_RS02800 ENOG4105D5T phosphonate abc transporter HEC95_RS02805 ENOG41068CG regulatoR HEC95_RS02830 ENOG4105SBG acid phosphatase HEC95_RS02845 ENOG4108SIC Transcriptional regulator HEC95_RS02850 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) HEC95_RS02860 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HEC95_RS02865 ENOG4108IJ0 Aspartate ammonia-lyase HEC95_RS02870 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HEC95_RS02875 ENOG4105DVH amino acid HEC95_RS02890 ENOG4108ZVF (LipO)protein HEC95_RS02895 ENOG4105MTB Uncharacterized protein YjeJ HEC95_RS02900 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HEC95_RS02905 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) HEC95_RS02915 ENOG4106BSU Entericidin B HEC95_RS02925 ENOG4105KPY Small multidrug resistance protein HEC95_RS02935 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) HEC95_RS02945 ENOG4105E33 succinate dehydrogenase HEC95_RS02950 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HEC95_RS02960 ENOG4107SC7 Inner membrane transporter yjeM HEC95_RS02965 ENOG4106CG8 Inner membrane protein YjeO HEC95_RS02970 ENOG4105EGS Mechanosensitive ion channel HEC95_RS02985 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) HEC95_RS02990 ENOG4106TNF Periplasmic binding protein HEC95_RS03010 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HEC95_RS03015 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HEC95_RS03020 ENOG4105K8N protein family UPF0079, ATPase HEC95_RS03025 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HEC95_RS03040 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) HEC95_RS03045 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HEC95_RS03050 ENOG4107QJR hflk protein HEC95_RS03055 ENOG4105EPW hflc protein HEC95_RS03075 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HEC95_RS03080 ENOG4105C2N RNA methyltransferase TrmH family group 3 HEC95_RS03085 ENOG4105FUX Conserved Protein HEC95_RS03090 ENOG4108P9J Phage shock protein A HEC95_RS03100 ENOG4107VNS Protein of unknown function (DUF2491) HEC95_RS03105 ENOG4105Z6B inner membrane protein yjfl HEC95_RS03110 ENOG4108KXT Conserved Protein HEC95_RS03115 ENOG4106032 Glutathionylspermidine synthase HEC95_RS03120 ENOG4105CSU acyl-Coa dehydrogenase HEC95_RS03125 ENOG4105S17 UPF0379 protein yjfN HEC95_RS03130 ENOG4105WSB biofilm stress and motility protein A HEC95_RS03135 ENOG4108MXZ Esterase HEC95_RS03150 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HEC95_RS03155 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport HEC95_RS03180 ENOG4105KIT UPF0379 protein yjfY HEC95_RS03185 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) HEC95_RS03190 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) HEC95_RS03195 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HEC95_RS03210 ENOG4105FHY Opacity-associated protein A HEC95_RS03215 ENOG4108V1T peptidylprolyl cis-trans isomerase HEC95_RS03240 ENOG4105DXC membrane HEC95_RS03245 ENOG4105ECR NmrA family HEC95_RS03250 ENOG4105KVH Transcriptional regulator HEC95_RS03255 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HEC95_RS03260 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HEC95_RS03265 ENOG4108UUE Transcriptional regulator HEC95_RS03270 ENOG41061GZ Protein of unknown function (DUF1107) HEC95_RS03275 ENOG4105C37 (CBS) domain HEC95_RS03295 ENOG4108ZHD aig2 family HEC95_RS03300 ENOG4105DJB Major Facilitator Superfamily HEC95_RS03305 ENOG41069H0 dihydroorotase EC 3.5.2.3 HEC95_RS03310 ENOG4105F0N pyrophosphate phospho-hydrolase HEC95_RS03320 ENOG4105DFU Cell wall formation (By similarity) HEC95_RS03330 ENOG4105CMS peptidase U62, modulator of DNA gyrase HEC95_RS03335 ENOG4108XVM Cytochrome b(562) HEC95_RS03365 ENOG41069H0 dihydroorotase EC 3.5.2.3 HEC95_RS03380 ENOG4105EMD TRANSCRIPTIONal HEC95_RS03390 ENOG4105K4U addiction module toxin, RelE StbE family HEC95_RS03395 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HEC95_RS03400 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HEC95_RS03405 ENOG4105CG3 alpha amylase, catalytic region HEC95_RS03410 ENOG4105C5Y PTS System HEC95_RS03415 ENOG4105D4X repressor HEC95_RS03435 ENOG4105KME endoribonuclease L-psp HEC95_RS03450 ENOG41077AM PyrBI operon attenuator HEC95_RS03460 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) HEC95_RS03465 ENOG4105CSX c4-dicarboxylate anaerobic carrier HEC95_RS03470 ENOG4105DBV ornithine carbamoyltransferase HEC95_RS03475 ENOG4105C5B carbamate kinase HEC95_RS03485 ENOG4105XEP YhcH YjgK YiaL family protein HEC95_RS03490 ENOG4105DBV ornithine carbamoyltransferase HEC95_RS03495 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HEC95_RS03500 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase HEC95_RS03510 ENOG4108MJ3 acetyltransferase HEC95_RS03515 ENOG4108M3P Membrane HEC95_RS03525 ENOG4105MYG DNA polymerase iii, chi subunit HEC95_RS03535 ENOG4108M8S permease YjgP YjgQ family protein HEC95_RS03540 ENOG4108K5H permease YjgP YjgQ family protein HEC95_RS03545 ENOG4105K2J Transcriptional regulator HEC95_RS03550 ENOG4105C6Z Gluconate HEC95_RS03555 ENOG4105CHR reductase HEC95_RS03560 ENOG4105CPQ Dehydrogenase HEC95_RS03565 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HEC95_RS03570 ENOG4105DQ4 alcohol dehydrogenase HEC95_RS03630 ENOG4108NKV transcriptional regulator HEC95_RS03655 ENOG4108ZK4 sdia-regulated domain-containing protein HEC95_RS03675 ENOG4105DTA methyltransferase HEC95_RS03685 ENOG4105KZM cytoplasmic protein HEC95_RS03705 ENOG4105C6F GntR Family Transcriptional Regulator HEC95_RS03725 ENOG4107YNJ LysR family Transcriptional regulator HEC95_RS03730 ENOG4105DYB Isoaspartyl dipeptidase HEC95_RS03735 ENOG4108P2H Inner membrane protein YjiG HEC95_RS03740 ENOG41074DU domain protein HEC95_RS03745 ENOG4105CBP Major Facilitator HEC95_RS03750 ENOG4106BRA Membrane HEC95_RS03755 ENOG41083G8 Multidrug resistance protein MdtM HEC95_RS03760 ENOG4105DNE Transposase HEC95_RS03765 ENOG4105C26 Dehydrogenase HEC95_RS03780 ENOG4108HFV HEC95_RS03785 ENOG4105DZR Type I site-specific deoxyribonuclease HEC95_RS03790 ENOG4105EKX Restriction modification system DNA (Specificity HEC95_RS03795 ENOG4105CVR type I restriction-modification system HEC95_RS03815 ENOG4105CKI cobalamin synthesis protein HEC95_RS03820 ENOG4105VCD cytoplasmic protein HEC95_RS03825 ENOG4105D22 carbon starvation protein HEC95_RS03830 ENOG4105C8Q Methyl-accepting chemotaxis HEC95_RS03845 ENOG4108IQ3 PTS system HEC95_RS03850 ENOG4105ETZ PTS System HEC95_RS03855 ENOG4105F3R pts system mannose fructose sorbose family iid HEC95_RS03860 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HEC95_RS03865 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HEC95_RS03875 ENOG4105RI1 glycoprotein receptor HEC95_RS03880 ENOG4106CVF DNA replication protein HEC95_RS03895 ENOG4105DWK Membrane HEC95_RS03900 ENOG4108N8T regulatoR HEC95_RS03905 ENOG4108T94 DNA-binding transcriptional activator BglJ HEC95_RS03910 ENOG4108UIN ybak prolyl-trna synthetase associated region HEC95_RS03915 ENOG4108819 ferric iron reductase HEC95_RS03920 ENOG4105BZU Histidine kinase HEC95_RS03925 ENOG4105YBH Protein of unknown function (DUF1435) HEC95_RS03950 ENOG4108WPU DNA polymerase III subunit psi HEC95_RS03955 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HEC95_RS03960 ENOG4105PAD Hydrolase HEC95_RS03970 ENOG4105K3G Periplasmic Protein HEC95_RS03980 ENOG4108NRW Phospholipase, patatin family HEC95_RS03985 ENOG4105EYA deoxyribonuclease HEC95_RS03990 ENOG41076CZ activating enzyme HEC95_RS03995 ENOG4105G0K glycine radical enzyme YjjI family HEC95_RS04020 ENOG4105EUP HipA domain protein HEC95_RS04030 ENOG41062Z9 Membrane HEC95_RS04035 ENOG4105EAC phosphoserine phosphatase HEC95_RS04040 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HEC95_RS04045 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HEC95_RS04050 ENOG4105C5H ABC transporter HEC95_RS04055 ENOG4107SC1 transglycosylase HEC95_RS04075 ENOG4105UEI Transcriptional Regulator AraC Family HEC95_RS04080 ENOG4108RH0 Crea protein HEC95_RS04085 ENOG4105E3W Two component transcriptional regulator (Winged helix family HEC95_RS04090 ENOG4105EB3 Histidine kinase HEC95_RS04095 ENOG4105CT7 inner membrane cred family protein HEC95_RS04110 ENOG4105CW0 outer membrane usher protein HEC95_RS04115 ENOG4108VCD Chaperone HEC95_RS04125 ENOG4108PNB DNA-binding transcriptional regulator HEC95_RS04135 ENOG41065U4 response regulator HEC95_RS04140 ENOG410759A HEC95_RS04145 ENOG4106FVC RNA methyltransferase HEC95_RS04155 ENOG4105CFH Aspartokinase HEC95_RS04165 ENOG4105D98 threonine synthase HEC95_RS04175 ENOG4105BZG amino acid carrier protein HEC95_RS04180 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HEC95_RS04185 ENOG4108RIR Molybdenum cofactor biosynthesis protein HEC95_RS04190 ENOG4106HK8 GPR1 FUN34 yaaH family protein HEC95_RS04195 ENOG4108QUJ UPF0174 protein YaaW HEC95_RS04255 ENOG4108AF8 Chaperone HEC95_RS04260 ENOG4105CW0 outer membrane usher protein HEC95_RS04265 ENOG4105MHR Fimbrial protein HEC95_RS04280 ENOG4106PH7 chaperone HEC95_RS04300 ENOG4105DQS Transcriptional regulator HEC95_RS04315 ENOG4105CGH 5'-nucleotidase HEC95_RS04325 ENOG41061MV Arylsulfatase HEC95_RS04330 ENOG4105C4X radical SAM domain protein HEC95_RS04350 ENOG41063Z6 transcriptional regulator, lysR family HEC95_RS04370 ENOG410647N response to DNA damage stimulus HEC95_RS04375 ENOG4105DTN riboflavin biosynthesis protein ribF HEC95_RS04390 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HEC95_RS04415 ENOG4106YYS transcriptional regulatory protein HEC95_RS04420 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HEC95_RS04425 ENOG4105D9Q decarboxylase (Beta subunit) HEC95_RS04430 ENOG4107QSA Oxaloacetate decarboxylase HEC95_RS04435 ENOG4106AFN Lyase and sodium transporter (By similarity) HEC95_RS04440 ENOG4105D2K citrate carrier protein HEC95_RS04445 ENOG4105DUA (citrate (pro-3S)-lyase ligase HEC95_RS04455 ENOG4105CI0 Citrate lyase HEC95_RS04460 ENOG4105CHY citrate lyase, alpha HEC95_RS04485 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HEC95_RS04490 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HEC95_RS04495 ENOG4108XNW Transcriptional activatory protein CaiF HEC95_RS04540 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HEC95_RS04545 ENOG4105WQV ferredoxin-like protein HEC95_RS04550 ENOG4105C54 Major Facilitator superfamily HEC95_RS04555 ENOG4105M5B (LipO)protein HEC95_RS04595 ENOG4105NWN ApaG protein HEC95_RS04605 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HEC95_RS04615 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HEC95_RS04625 ENOG4105D3G Pseudouridine synthase HEC95_RS04635 ENOG4105CQ2 DNA polymerase HEC95_RS04655 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HEC95_RS04670 ENOG41063TF transcriptional regulator (AraC HEC95_RS04675 ENOG4108KF1 Membrane HEC95_RS04680 ENOG4107T0D ABC, transporter HEC95_RS04720 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HEC95_RS04735 ENOG41064T2 transcriptional regulator, lysR family HEC95_RS04740 ENOG4105C7K acetolactate synthase HEC95_RS04745 ENOG4108ZP8 Acetolactate synthase small subunit HEC95_RS04750 ENOG4107B7Y DNA-binding transcriptional regulator FruR HEC95_RS04765 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HEC95_RS04770 ENOG4105CJN penicillin-binding protein HEC95_RS04775 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HEC95_RS04780 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HEC95_RS04790 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) HEC95_RS04795 ENOG4105CNI cell division protein FtsW HEC95_RS04815 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HEC95_RS04820 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HEC95_RS04825 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HEC95_RS04835 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) HEC95_RS04845 ENOG4105M6F mutator MutT protein HEC95_RS04855 ENOG410642W LysR family Transcriptional regulator HEC95_RS04870 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HEC95_RS04880 ENOG4105D7Q type ii secretion system HEC95_RS04885 ENOG4107QHF type ii secretion system protein e HEC95_RS04890 ENOG4108ZUW Major pilin subunit HEC95_RS04895 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HEC95_RS04905 ENOG4106A72 regulatory protein AmpE HEC95_RS04910 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) HEC95_RS04915 ENOG4105CT4 transporter HEC95_RS04930 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HEC95_RS04935 ENOG4107QSN dihydrolipoamide acetyltransferase HEC95_RS04940 ENOG4107QN2 dihydrolipoyl dehydrogenase HEC95_RS04955 ENOG4108NST exported protein HEC95_RS04960 ENOG4107QIJ Aconitate hydratase 2 HEC95_RS04965 ENOG4106HGK Inner membrane protein yieI HEC95_RS04980 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) HEC95_RS04985 ENOG4107S2N Type III effector Hrp-dependent HEC95_RS04990 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HEC95_RS04995 ENOG4105MVE transcriptional regulator HEC95_RS05010 ENOG4108ZRK uncharacterized protein yacC HEC95_RS05015 ENOG4105E3B Multicopper oxidase HEC95_RS05020 ENOG4105DZG Dehydrogenase HEC95_RS05025 ENOG4108UGV hypoxanthine phosphoribosyltransferase HEC95_RS05030 ENOG41077A9 carbonic anhydrase HEC95_RS05035 ENOG4105DA5 (ABC) transporter HEC95_RS05040 ENOG4105E3A (ABC) transporter HEC95_RS05045 ENOG4108MDY Fimbrial HEC95_RS05050 ENOG4105CW0 outer membrane usher protein HEC95_RS05055 ENOG4108UIF Chaperone HEC95_RS05065 ENOG4108YTN IIa component HEC95_RS05070 ENOG4107BJW polysaccharide deacetylase HEC95_RS05090 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HEC95_RS05095 ENOG4105DJ0 Poly(A) Polymerase HEC95_RS05100 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) HEC95_RS05105 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters HEC95_RS05115 ENOG4107XID 2'-5' rna ligase HEC95_RS05120 ENOG4105CQ7 ATP-dependent helicase HEC95_RS05125 ENOG4105BZ4 penicillin-binding protein HEC95_RS05130 ENOG4105E0K tonB-dependent siderophore receptor HEC95_RS05135 ENOG4105E0A ABC, transporter HEC95_RS05140 ENOG4105J76 Periplasmic binding protein HEC95_RS05145 ENOG4105S6R Iron-hydroxamate transporter permease subunit HEC95_RS05155 ENOG4106PG1 outer membrane usher protein HEC95_RS05160 ENOG4108FZ9 Chaperone HEC95_RS05165 ENOG4105NEV Fimbrial HEC95_RS05170 ENOG4105UGQ Fimbrial HEC95_RS05180 ENOG4106RDH Protein of unknown function (DUF2544) HEC95_RS05195 ENOG4108YX9 iron--sulfur cluster insertion protein erpA HEC95_RS05200 ENOG4105EN6 Membrane HEC95_RS05205 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HEC95_RS05220 ENOG4105C0H protease HEC95_RS05225 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HEC95_RS05240 ENOG4105CSH Transporter HEC95_RS05255 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HEC95_RS05260 ENOG4105CE9 30S ribosomal protein S2 HEC95_RS05270 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) HEC95_RS05275 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) HEC95_RS05290 ENOG4105KNE Phosphatidate cytidylyltransferase HEC95_RS05305 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HEC95_RS05310 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HEC95_RS05315 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) HEC95_RS05335 ENOG4105C0B DNA polymerase III (alpha subunit) HEC95_RS05345 ENOG4108M1A Chitin-binding protein HEC95_RS05350 ENOG4105CXN decarboxylase HEC95_RS05355 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HEC95_RS05365 ENOG4105M1T rho-binding antiterminator HEC95_RS05375 ENOG4108VWS Yaeq family HEC95_RS05380 ENOG4108YZN class I peptide chain release factor HEC95_RS05385 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HEC95_RS05395 ENOG4108R96 Methyltransferase, YaeB family HEC95_RS05400 ENOG4108R8X outer membrane lipoprotein HEC95_RS05405 ENOG4105D01 (LipO)protein HEC95_RS05410 ENOG4108UMI ABC transporter, permease HEC95_RS05415 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HEC95_RS05420 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HEC95_RS05455 ENOG4105CV8 reductase HEC95_RS05460 ENOG4105HEI LysR family (Transcriptional regulator HEC95_RS05465 ENOG4105F27 Major Facilitator HEC95_RS05475 ENOG4105F2W methyltransferase HEC95_RS05480 ENOG4105E9H Lytic Murein transglycosylase HEC95_RS05490 ENOG4105D1A Methyltransferase HEC95_RS05495 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) HEC95_RS05500 ENOG4107RZZ dna polymerase iii epsilon subunit HEC95_RS05535 ENOG4105CNA YD repeat protein HEC95_RS05615 ENOG4105W7K Transcriptional regulator HEC95_RS05625 ENOG4105T40 surface antigen msp4 family protein HEC95_RS05635 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HEC95_RS05640 ENOG4107QPN acyl-Coa dehydrogenase HEC95_RS05650 ENOG4105E7A Glutamine amidotransferase HEC95_RS05655 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HEC95_RS05670 ENOG4108S2Y peptide Chain Release factor HEC95_RS05675 ENOG4105CIN aminoacyl-histidine dipeptidase HEC95_RS05680 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) HEC95_RS05695 ENOG4105FCK Membrane HEC95_RS05725 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit HEC95_RS05730 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit HEC95_RS05735 ENOG4105V2F Uncharacterized protein yoac HEC95_RS05740 ENOG4105D94 Major Facilitator Superfamily HEC95_RS05745 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) HEC95_RS05750 ENOG4108TFY Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) HEC95_RS05755 ENOG4105ERH Fumarylacetoacetate hydrolase HEC95_RS05765 ENOG4105EJC lysr family transcriptional regulator HEC95_RS05790 ENOG4105CW0 outer membrane usher protein HEC95_RS05795 ENOG4108VEV chaperone HEC95_RS05800 ENOG4105X0I Fimbrial HEC95_RS05815 ENOG4107XTP (EAL) domain protein HEC95_RS05830 ENOG4108T1M outer membrane protein x HEC95_RS05850 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HEC95_RS05860 ENOG4105C1P efflux transporter, rnd family, mfp subunit HEC95_RS05880 ENOG4105JHE Major Facilitator Superfamily HEC95_RS05885 ENOG4107QMH DNA methylase HEC95_RS05890 ENOG4105D8D Type III HEC95_RS05900 ENOG4105C4M (Ubiquinol oxidase) subunit I HEC95_RS05905 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HEC95_RS05925 ENOG4105E82 cytochrome subunit of dehydrogenase HEC95_RS05930 ENOG4105TDT uncharacterized protein yahO HEC95_RS05935 ENOG4108JU7 Transcriptional regulator HEC95_RS05940 ENOG4105CR4 methylisocitrate lyase HEC95_RS05945 ENOG4105BZN citrate synthase HEC95_RS05950 ENOG4105DXD 2-methylcitrate dehydratase HEC95_RS05955 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HEC95_RS05960 ENOG4105D52 delta-aminolevulinic acid dehydratase HEC95_RS05965 ENOG4108NSE outer membrane autotransporter barrel HEC95_RS05970 ENOG4108PNB DNA-binding transcriptional regulator HEC95_RS05975 ENOG4107R6D beta-lactam binding protein AmpH HEC95_RS05980 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HEC95_RS05985 ENOG4107QS8 (LipO)protein HEC95_RS05990 ENOG4105FR5 inner membrane protein YaiY HEC95_RS05995 ENOG4105UNH Membrane HEC95_RS06000 ENOG4105CPF Cell wall formation (By similarity) HEC95_RS06020 ENOG4105VIF phosphate starvation-inducible protein HEC95_RS06025 ENOG4105BZU Histidine kinase HEC95_RS06030 ENOG4105II7 pyrroline-5-carboxylate reductase HEC95_RS06045 ENOG4105SS3 HEC95_RS06050 ENOG4105HBA AroM protein HEC95_RS06065 ENOG4105DKQ ROK family HEC95_RS06070 ENOG4105F27 Major Facilitator HEC95_RS06075 ENOG4105EYH Exonuclease HEC95_RS06080 ENOG4107RH8 nuclease SbcCD subunit D HEC95_RS06085 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HEC95_RS06090 ENOG4105BZU Histidine kinase HEC95_RS06095 ENOG4105CWM branched-chain amino acid transport system II carrier protein HEC95_RS06100 ENOG4105C85 amino acid HEC95_RS06105 ENOG4107R28 alpha amylase, catalytic region HEC95_RS06110 ENOG4105D3R alkyl hydroperoxide reductase HEC95_RS06130 ENOG4105VIE preprotein translocase, subunit YajC HEC95_RS06140 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HEC95_RS06155 ENOG4105N1F Hnh endonuclease HEC95_RS06165 ENOG4105DRB nucleoside-specific channel-forming protein HEC95_RS06170 ENOG4108KIC (LipO)protein HEC95_RS06180 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HEC95_RS06190 ENOG4107YIM Involved in the transcription termination process (By similarity) HEC95_RS06195 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HEC95_RS06200 ENOG4108ZAI phosphatidylglycerophosphatase a HEC95_RS06205 ENOG4105CPC Aldo Keto reductase HEC95_RS06215 ENOG4105CTB Polyprenyl synthetase HEC95_RS06220 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) HEC95_RS06230 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component HEC95_RS06240 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HEC95_RS06250 ENOG4106S9K Transcriptional regulator HEC95_RS06265 ENOG4107S0N DJ-1 family HEC95_RS06270 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HEC95_RS06280 ENOG4107RDB Major Facilitator HEC95_RS06300 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HEC95_RS06305 ENOG4105CCU oxidase (Subunit III) HEC95_RS06310 ENOG4105BZ9 Cytochrome C oxidase, subunit I HEC95_RS06315 ENOG4105E2S oxidase) subunit II HEC95_RS06320 ENOG4105EYM Major Facilitator superfamily HEC95_RS06325 ENOG4105IEY (LipO)protein HEC95_RS06330 ENOG4105M85 Bola protein HEC95_RS06350 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HEC95_RS06355 ENOG4105K70 DNA-binding protein HEC95_RS06360 ENOG4105EIN peptidylprolyl cis-trans isomerase HEC95_RS06365 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HEC95_RS06370 ENOG4108TGP Thioesterase superfamily protein HEC95_RS06380 ENOG4108NFA extracellular solute-binding protein HEC95_RS06395 ENOG4108XM1 transcriptional regulator AsnC family HEC95_RS06400 ENOG4105BZ1 (ABC) transporter HEC95_RS06405 ENOG4105BZ1 (ABC) transporter HEC95_RS06410 ENOG4108YZA Nitrogen regulatory protein pii HEC95_RS06415 ENOG4105BZU Histidine kinase HEC95_RS06420 ENOG4105C29 acyl-CoA thioesterase HEC95_RS06425 ENOG4108MNP Glycoprotein polysaccharide metabolism HEC95_RS06430 ENOG41080UX Methyltransferase HEC95_RS06440 ENOG41066DG (EAL) domain protein HEC95_RS06455 ENOG4105GSJ Inner membrane protein ylaC HEC95_RS06460 ENOG4108UW5 maltose o-acetyltransferase HEC95_RS06470 ENOG4108UKR Biofilm formation regulator YbaJ HEC95_RS06475 ENOG4105BZS acriflavin resistance protein HEC95_RS06480 ENOG4105C1P efflux transporter, rnd family, mfp subunit HEC95_RS06485 ENOG4107XI7 Tetr family transcriptional regulator HEC95_RS06490 ENOG4105EGS Mechanosensitive ion channel HEC95_RS06495 ENOG4105DNE Transposase HEC95_RS06500 ENOG4106428 Protein of unknown function (DUF2496) HEC95_RS06505 ENOG4108URS primosomal replication protein n'' HEC95_RS06510 ENOG4105WD1 Membrane HEC95_RS06520 ENOG4107QMP dna polymerase iii subunits gamma and tau HEC95_RS06555 ENOG4107RE1 Inosine-guanosine kinase HEC95_RS06560 ENOG4105CKD glutathione-regulated potassium-efflux system protein HEC95_RS06565 ENOG4105EU0 Major facilitator Superfamily HEC95_RS06575 ENOG4108Z66 YbaK ebsC protein HEC95_RS06580 ENOG4105MBR gumn family HEC95_RS06590 ENOG4105C59 p-type ATPase HEC95_RS06595 ENOG4108Z6Z Transcriptional regulator HEC95_RS06600 ENOG4105G5H Membrane HEC95_RS06605 ENOG4107QX8 SPFH domain, Band 7 family protein HEC95_RS06610 ENOG41083J0 (ABC) transporter HEC95_RS06615 ENOG4105C4B ABC transporter, permease HEC95_RS06620 ENOG4107QR8 Thioredoxin HEC95_RS06625 ENOG4105E1F short-chain dehydrogenase reductase HEC95_RS06630 ENOG4108UJV acyl-CoA thioesterase i HEC95_RS06635 ENOG4108I0Y (ABC) transporter HEC95_RS06640 ENOG4105CV6 ABC transporter, permease HEC95_RS06650 ENOG4105D01 (LipO)protein HEC95_RS06655 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HEC95_RS06660 ENOG4108UMI ABC transporter, permease HEC95_RS06685 ENOG41060W2 glyoxylate carboligase HEC95_RS06690 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HEC95_RS06695 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HEC95_RS06705 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HEC95_RS06715 ENOG4105DTE Xanthine uracil vitamin C permease HEC95_RS06720 ENOG4105BZW Glycerate kinase HEC95_RS06725 ENOG4105S0E allantoin catabolism protein HEC95_RS06730 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HEC95_RS06735 ENOG4105DG4 malate L-lactate dehydrogenase HEC95_RS06740 ENOG4107R1Q Membrane protein FdrA HEC95_RS06745 ENOG4107REC cytoplasmic protein HEC95_RS06750 ENOG4105G5A Protein of unknown function (DUF2877) HEC95_RS06755 ENOG4105C5B carbamate kinase HEC95_RS06760 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HEC95_RS06765 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HEC95_RS06775 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HEC95_RS06795 ENOG4105S2T inner membrane protein YbcI HEC95_RS06800 ENOG4105WQ3 Rna-binding protein HEC95_RS06810 ENOG4108WDE Fimbrial protein HEC95_RS06820 ENOG4108AF8 Chaperone HEC95_RS06825 ENOG4105CW0 outer membrane usher protein HEC95_RS06830 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) HEC95_RS06835 ENOG4108ZI2 Fimbrial protein HEC95_RS06840 ENOG4108Q9V regulatoR HEC95_RS06845 ENOG4106721 fimbriae Y protein HEC95_RS06855 ENOG4106KCD HTH_LUXR HEC95_RS06875 ENOG4105CKK Glycosyl transferase, family 2 HEC95_RS06880 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) HEC95_RS06900 ENOG4108K01 transcriptional regulator HEC95_RS06905 ENOG4107QN2 dihydrolipoyl dehydrogenase HEC95_RS06910 ENOG41066GK UPF0379 protein ykgI HEC95_RS06915 ENOG4108KBJ Inner membrane protein YkgB HEC95_RS06925 ENOG4105C85 amino acid HEC95_RS06930 ENOG4105CUY Mechanosensitive ion channel HEC95_RS06940 ENOG4108RCM Nitroreductase HEC95_RS06945 ENOG4105MSB protein, conserved in bacteria HEC95_RS06950 ENOG41067SE Tetr family transcriptional regulator HEC95_RS06955 ENOG4105HFT AraC family transcriptional regulator HEC95_RS06960 ENOG4105WQ6 Membrane HEC95_RS06970 ENOG4108TSE Transferase HEC95_RS06975 ENOG4107RNH Outer membrane receptor FepA HEC95_RS06980 ENOG4105E93 esterase HEC95_RS06985 ENOG41085A6 mbth domain-containing protein HEC95_RS06990 ENOG4105C0W non-ribosomal peptide synthetase HEC95_RS06995 ENOG4108QY5 Ferric enterobactin transport protein HEC95_RS07000 ENOG4105E0A ABC, transporter HEC95_RS07005 ENOG4105TVJ transport system, permease HEC95_RS07010 ENOG4105DQ5 transport system permease protein HEC95_RS07015 ENOG4105E8G Major facilitator Superfamily HEC95_RS07020 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HEC95_RS07025 ENOG4105E4F Isochorismate synthase HEC95_RS07030 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HEC95_RS07035 ENOG4105WQI isochorismatase HEC95_RS07040 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HEC95_RS07050 ENOG4105D22 carbon starvation protein HEC95_RS07055 ENOG4105VCD cytoplasmic protein HEC95_RS07060 ENOG4107SCQ Iron-containing alcohol dehydrogenase HEC95_RS07065 ENOG4105CHM Aminotransferase HEC95_RS07070 ENOG4105GTN ParB Domain Protein Nuclease HEC95_RS07075 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HEC95_RS07080 ENOG4105DQS Transcriptional regulator HEC95_RS07085 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HEC95_RS07090 ENOG4105D3R alkyl hydroperoxide reductase HEC95_RS07095 ENOG4108JU3 Alkyl hydroperoxide reductase HEC95_RS07105 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) HEC95_RS07110 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HEC95_RS07120 ENOG4108U51 Universal stress protein HEC95_RS07125 ENOG4105E2A Dehydrogenase HEC95_RS07130 ENOG4105NXH GreA GreB family elongation factor HEC95_RS07135 ENOG4105KTS ribonuclease HEC95_RS07140 ENOG4107QPK )-transporter HEC95_RS07150 ENOG4105YGP holo-ACP synthase CitX HEC95_RS07155 ENOG4105CHY citrate lyase, alpha HEC95_RS07160 ENOG4105CI0 Citrate lyase HEC95_RS07165 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) HEC95_RS07170 ENOG4105DUA (citrate (pro-3S)-lyase ligase HEC95_RS07175 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HEC95_RS07180 ENOG4106YYS transcriptional regulatory protein HEC95_RS07185 ENOG4105CEE C4-dicarboxylate transporter HEC95_RS07200 ENOG4107Z6W Protein CrcB homolog HEC95_RS07220 ENOG41064T2 transcriptional regulator, lysR family HEC95_RS07230 ENOG4108Z43 UPF0250 protein HEC95_RS07235 ENOG4105DZ1 carboxypeptidase HEC95_RS07240 ENOG4105K6T rare lipoprotein A HEC95_RS07245 ENOG4105CNI cell division protein FtsW HEC95_RS07250 ENOG4105CJN penicillin-binding protein HEC95_RS07255 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) HEC95_RS07260 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HEC95_RS07265 ENOG4108TGR phosphatase HEC95_RS07270 ENOG4107QZB decarboxylase HEC95_RS07280 ENOG4105DJF DNA polymerase III, delta' subunit HEC95_RS07305 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) HEC95_RS07310 ENOG4108JUB Transcriptional regulator HEC95_RS07315 ENOG4107PAI alpha helical protein HEC95_RS07325 ENOG41069CF Protein of unknown function (DUF1266) HEC95_RS07330 ENOG4105QFC Hsc56 co-chaperone of HscC HEC95_RS07335 ENOG41069CF Protein of unknown function (DUF1266) HEC95_RS07340 ENOG4105QFC Hsc56 co-chaperone of HscC HEC95_RS07345 ENOG4105F7F Chaperone HEC95_RS07365 ENOG4105CDA abc transporter atp-binding protein HEC95_RS07370 ENOG4105DRP amino acid AbC transporter HEC95_RS07375 ENOG4105EAD ABC transporter HEC95_RS07380 ENOG4107RP9 extracellular solute-binding protein, family 3 HEC95_RS07385 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HEC95_RS07390 ENOG4108JU5 Magnesium and cobalt efflux protein HEC95_RS07400 ENOG4105C9A Phoh family HEC95_RS07410 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HEC95_RS07455 ENOG4105CAQ asparagine synthetase HEC95_RS07460 ENOG4105D4U had-superfamily hydrolase, subfamily iia HEC95_RS07465 ENOG4105E2R ROK family HEC95_RS07470 ENOG4105CE4 GlcNAc 6-P deacetylase HEC95_RS07480 ENOG4105CI1 PTS System HEC95_RS07490 ENOG4105J5J Outer membrane porin HEC95_RS07495 ENOG4105GX6 (LipO)protein HEC95_RS07500 ENOG4105CSH Transporter HEC95_RS07505 ENOG41079YP Citrate utilization protein b HEC95_RS07510 ENOG4107EFR Flavocytochrome c HEC95_RS07515 ENOG4106P55 Transcriptional regulator HEC95_RS07520 ENOG41090R7 Ferric uptake HEC95_RS07525 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HEC95_RS07530 ENOG4105NNH LexA regulated protein HEC95_RS07535 ENOG4105EV9 Alpha Beta Hydrolase HEC95_RS07540 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HEC95_RS07545 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HEC95_RS07555 ENOG4105D5Q Arginine ornithine antiporter HEC95_RS07560 ENOG4105CXN decarboxylase HEC95_RS07570 ENOG4105EEX Two component transcriptional regulator (Winged helix family HEC95_RS07575 ENOG4105C08 Histidine kinase HEC95_RS07600 ENOG4105XIQ Protein of unknown function (DUF2517) HEC95_RS07605 ENOG4105CVP deoxyribo-dipyrimidine photolyase HEC95_RS07615 ENOG4107QNR UPF0135 protein HEC95_RS07620 ENOG4105P4J Allophanate hydrolase, subunit 1 HEC95_RS07625 ENOG4107R7A Allophanate hydrolase subunit 2 HEC95_RS07640 ENOG4108KK1 membrane protein AbrB duplication HEC95_RS07645 ENOG4105BZN citrate synthase HEC95_RS07655 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HEC95_RS07660 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HEC95_RS07665 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HEC95_RS07670 ENOG4105E33 succinate dehydrogenase HEC95_RS07675 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HEC95_RS07680 ENOG4105C7S Dehydrogenase HEC95_RS07690 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HEC95_RS07695 ENOG4105C4M (Ubiquinol oxidase) subunit I HEC95_RS07700 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HEC95_RS07710 ENOG4105KJB cyd operon protein YbgE HEC95_RS07715 ENOG4107YD3 Thioesterase HEC95_RS07720 ENOG4105E02 MotA TolQ exbB proton channel HEC95_RS07730 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HEC95_RS07740 ENOG4105KCK Peptidoglycan-associated lipoprotein HEC95_RS07745 ENOG4105UFD tol-pal system protein YbgF HEC95_RS07790 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HEC95_RS07795 ENOG4105PGM cation diffusion facilitator family transporter HEC95_RS07800 ENOG4105JND homeobox protein HEC95_RS07805 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HEC95_RS07810 ENOG4107GFK fumarate HEC95_RS07815 ENOG4106DSS Tartrate dehydratase subunit alpha HEC95_RS07820 ENOG4105C5Q Transcriptional regulator HEC95_RS07840 ENOG4107QSA Oxaloacetate decarboxylase HEC95_RS07845 ENOG4105D9Q decarboxylase (Beta subunit) HEC95_RS07850 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase HEC95_RS07855 ENOG4105EHG Permease protein HEC95_RS07860 ENOG4105E0A ABC, transporter HEC95_RS07870 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HEC95_RS07880 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HEC95_RS07885 ENOG4105CMR udp-glucose 4-epimerase HEC95_RS07895 ENOG4105DKW ABC transporter HEC95_RS07900 ENOG4105F4R Transcriptional regulator mode HEC95_RS07910 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HEC95_RS07915 ENOG4105E0C molybdate abc transporter HEC95_RS07925 ENOG4108K4B hydrolase HEC95_RS07935 ENOG4105NBR Pectinesterase HEC95_RS07965 ENOG4108V1U phospholipid-binding protein HEC95_RS07970 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HEC95_RS07985 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HEC95_RS07990 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HEC95_RS08010 ENOG4105CHW UPF0052 protein HEC95_RS08020 ENOG4108RIR Molybdenum cofactor biosynthesis protein HEC95_RS08030 ENOG4105M00 molybdopterin converting factor, subunit 1 HEC95_RS08035 ENOG4108ZAF Molybdopterin HEC95_RS08040 ENOG4105HFZ Membrane HEC95_RS08060 ENOG4107UXM Membrane HEC95_RS08065 ENOG4105DZQ phospholipase D Transphosphatidylase HEC95_RS08070 ENOG4105X23 Endonuclease Exonuclease phosphatase HEC95_RS08075 ENOG4105I9U inner membrane protein ybhQ HEC95_RS08080 ENOG4107QWP ABC-2 type transporter HEC95_RS08085 ENOG4107QWP ABC-2 type transporter HEC95_RS08090 ENOG4105CJ1 ABC, transporter HEC95_RS08100 ENOG4107MVR Transcriptional regulator HEC95_RS08105 ENOG4105C1J atp-dependent rna helicase HEC95_RS08110 ENOG4105DVT helicase HEC95_RS08115 ENOG4108MTB glycosyl transferase family HEC95_RS08120 ENOG4105VR4 UPF0379 protein ybiJ HEC95_RS08125 ENOG4105KSC Transcriptional regulator, TraR DksA family HEC95_RS08135 ENOG4105D8X mechanosensitive ion channel HEC95_RS08140 ENOG4105CDA abc transporter atp-binding protein HEC95_RS08145 ENOG4105E5Q amino acid AbC transporter HEC95_RS08150 ENOG4107R0W ABC transporter HEC95_RS08165 ENOG4108T1M outer membrane protein x HEC95_RS08170 ENOG4108I6E Sulfatase HEC95_RS08180 ENOG4105KST dependent repressor HEC95_RS08185 ENOG4105F4P )-transporter HEC95_RS08190 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HEC95_RS08195 ENOG4105C5H ABC transporter HEC95_RS08210 ENOG41072TH Protein of unknown function (DUF1479) HEC95_RS08215 ENOG4108HCJ Hydrolase HEC95_RS08225 ENOG4105F1A Pyruvate formate-lyase HEC95_RS08230 ENOG4105D06 uba thif-type nad fad binding protein HEC95_RS08235 ENOG4105CVM Molybdenum cofactor synthesis domain protein HEC95_RS08240 ENOG4105D44 asparaginase HEC95_RS08245 ENOG4108JQ6 ABC transporter HEC95_RS08250 ENOG4105DEF Extracellular solute-binding protein, family 5 HEC95_RS08270 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HEC95_RS08275 ENOG4105CI0 Citrate lyase HEC95_RS08280 ENOG4105BZJ Electron transfer flavoprotein HEC95_RS08285 ENOG4105C10 Electron transfer flavoprotein HEC95_RS08290 ENOG4108M9J MaoC like domain protein HEC95_RS08295 ENOG4105C1G acyl-Coa dehydrogenase HEC95_RS08300 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HEC95_RS08305 ENOG4108KB2 LysR family Transcriptional regulator HEC95_RS08310 ENOG4105CY2 Citrate transporter HEC95_RS08315 ENOG4105D8V Glucose sorbosone dehydrogenase HEC95_RS08320 ENOG4105D8V Glucose sorbosone dehydrogenase HEC95_RS08325 ENOG4108TGY Glutathione S-transferase HEC95_RS08330 ENOG4105DZ1 carboxypeptidase HEC95_RS08335 ENOG4107FB0 transcriptional regulator DeoR family HEC95_RS08340 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HEC95_RS08345 ENOG4107QF7 multi-drug HEC95_RS08350 ENOG4108HCJ Hydrolase HEC95_RS08355 ENOG4106UW1 Major Facilitator superfamily HEC95_RS08360 ENOG4108RFG Tetr family transcriptional regulator HEC95_RS08370 ENOG4105GWF inner membrane protein YbjM HEC95_RS08375 ENOG41090BQ Glutaredoxin HEC95_RS08380 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HEC95_RS08395 ENOG4108RMJ sensory transduction regulator HEC95_RS08400 ENOG4107RUE extracellular solute-binding protein family 1 HEC95_RS08405 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HEC95_RS08410 ENOG4105F38 ABC transporter, permease HEC95_RS08415 ENOG4105D38 putrescine abc transporter HEC95_RS08420 ENOG4105RBQ inner membrane protein ybjO HEC95_RS08445 ENOG4106TNF Periplasmic binding protein HEC95_RS08450 ENOG4105DMR ABC, transporter HEC95_RS08455 ENOG4105GBT ABC transporter HEC95_RS08460 ENOG4106PMH Extracellular solute-binding protein family 3 HEC95_RS08465 ENOG4105E5Z arginine transporter ATP-binding subunit HEC95_RS08470 ENOG41064MM (LipO)protein HEC95_RS08480 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HEC95_RS08485 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HEC95_RS08490 ENOG4105CGD Nad-dependent epimerase dehydratase HEC95_RS08495 ENOG4105C5W Aldolase HEC95_RS08500 ENOG4105C7K acetolactate synthase HEC95_RS08505 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HEC95_RS08515 ENOG4105DWU Membrane HEC95_RS08520 ENOG4105CPB ATP-dependent endonuclease of the OLD family HEC95_RS08525 ENOG4108MJ5 VirK protein HEC95_RS08530 ENOG4105DJY efflux transporter, rnd family, mfp subunit HEC95_RS08535 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HEC95_RS08540 ENOG4105VEQ Cold shock protein HEC95_RS08550 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HEC95_RS08570 ENOG4105CHJ isochorismatase hydrolase HEC95_RS08575 ENOG4105EUB pirin domain protein HEC95_RS08580 ENOG4105HEI LysR family (Transcriptional regulator HEC95_RS08585 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HEC95_RS08600 ENOG4108JJ8 (ABC) transporter HEC95_RS08605 ENOG4108JJ9 ABC, transporter HEC95_RS08610 ENOG4105C3M thioredoxin reductase HEC95_RS08615 ENOG4105EW9 transcriptional regulator AsnC family HEC95_RS08620 ENOG4105CNU cell division protein FtsK HEC95_RS08630 ENOG4105D1H recombination factor protein RarA HEC95_RS08640 ENOG4107QY8 reductase HEC95_RS08645 ENOG4105QAX Iron-sulfur HEC95_RS08650 ENOG4107KGK dmso reductase anchor subunit HEC95_RS08660 ENOG4105E5D amino acid HEC95_RS08665 ENOG4105F1A Pyruvate formate-lyase HEC95_RS08675 ENOG4105GUS HEC95_RS08680 ENOG4105C6N Formate acetyltransferase HEC95_RS08685 ENOG4105TMB Formate nitrite transporter HEC95_RS08690 ENOG4105DDY UPF0142 protein ycaO HEC95_RS08695 ENOG4107VMU Membrane HEC95_RS08710 ENOG4108K0D peptidase, M48 HEC95_RS08720 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HEC95_RS08725 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) HEC95_RS08730 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HEC95_RS08735 ENOG4105BZ1 (ABC) transporter HEC95_RS08745 ENOG4105T0Z Conserved Protein HEC95_RS08760 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HEC95_RS08765 ENOG4107S90 membrAne HEC95_RS08770 ENOG4106371 Methyltransferase HEC95_RS08780 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HEC95_RS08790 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HEC95_RS08795 ENOG4105EAQ (twin-arginine translocation) pathway signal HEC95_RS08800 ENOG4105C5X domain protein HEC95_RS08805 ENOG4105CGF Aromatic amino acid aminotransferase HEC95_RS08810 ENOG4105FCK Membrane HEC95_RS08815 ENOG4105C5S asparaginyl-tRNA synthetase HEC95_RS08825 ENOG4107RCH Diaminopropionate ammonia-lyase HEC95_RS08840 ENOG4107R08 Integrase HEC95_RS08855 ENOG410685N tail fiber protein HEC95_RS08860 ENOG4105UZW Tail fiber assembly protein HEC95_RS08875 ENOG4106EE1 HEC95_RS08885 ENOG4108RAV Conserved protein HEC95_RS08900 ENOG4105Y50 Virulence Protein HEC95_RS08905 ENOG4105CD8 aminopeptidase N HEC95_RS08915 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HEC95_RS08920 ENOG4105QVC MOSC domain-containing protein HEC95_RS08930 ENOG4105C5H ABC transporter HEC95_RS08935 ENOG4105F1S paraquat-inducible protein a HEC95_RS08940 ENOG4105DY2 Paraquat-inducible protein b HEC95_RS08945 ENOG4108Q2G (LipO)protein HEC95_RS08950 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HEC95_RS08960 ENOG4105DAN ATP-dependent protease HEC95_RS08970 ENOG4105UYK outer membrane protein a HEC95_RS08980 ENOG4108RZ1 DNA transformation protein HEC95_RS08985 ENOG4105EM2 membrane HEC95_RS08990 ENOG410901E Membrane HEC95_RS08995 ENOG41088T4 Helicase IV HEC95_RS09000 ENOG4108Z5K methylglyoxal synthase HEC95_RS09010 ENOG4105K4P CoA-binding domain protein HEC95_RS09025 ENOG4108V1U phospholipid-binding protein HEC95_RS09035 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HEC95_RS09045 ENOG4108MN8 Membrane HEC95_RS09060 ENOG41084BJ Pentapeptide repeat protein HEC95_RS09070 ENOG4106HNN Invasion protein HEC95_RS09075 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell HEC95_RS09080 ENOG4106YSC HEC95_RS09095 ENOG4107ZY3 Histidine kinase HEC95_RS09100 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HEC95_RS09110 ENOG4107UWN reductase HEC95_RS09115 ENOG4105EFA 4-hydroxyphenylacetate HEC95_RS09120 ENOG4108V8F Transcriptional regulator, MarR family HEC95_RS09130 ENOG4105C26 Dehydrogenase HEC95_RS09135 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase HEC95_RS09190 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) HEC95_RS09195 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) HEC95_RS09200 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HEC95_RS09210 ENOG4105XH3 HEC95_RS09215 ENOG4105CS1 NAD(P)H quinone oxidoreductase HEC95_RS09220 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HEC95_RS09225 ENOG4108R86 Transcriptional regulator HEC95_RS09240 ENOG4105CK7 Sodium proline symporter HEC95_RS09245 ENOG4105D5M phosphate starvation-inducible protein HEC95_RS09250 ENOG4105QEK Transcriptional regulator HEC95_RS09255 ENOG4107RJ1 sodium solute HEC95_RS09260 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) HEC95_RS09270 ENOG4108QGT oligogalacturonate-specific porin HEC95_RS09275 ENOG4105JHE Major Facilitator Superfamily HEC95_RS09280 ENOG4107RJ5 oxidoreductase HEC95_RS09315 ENOG4105GMB type VI secretion system effector, hcp1 family HEC95_RS09340 ENOG4105CNA YD repeat protein HEC95_RS09365 ENOG410600K aminopeptidase HEC95_RS09390 ENOG4105FCK Membrane HEC95_RS09395 ENOG4105Y0K Inner membrane protein YedR HEC95_RS09400 ENOG4105EST Metal Dependent Phosphohydrolase HEC95_RS09405 ENOG4105DVF Cytosine-specific methyltransferase HEC95_RS09410 ENOG41090BB DNA mismatch endonuclease (vsr) HEC95_RS09415 ENOG4105FDR Membrane HEC95_RS09420 ENOG4105CKW Inner membrane protein yedI HEC95_RS09425 ENOG4105VNZ cytoplasmic protein HEC95_RS09435 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase HEC95_RS09440 ENOG4105YX3 cellular response to acidity HEC95_RS09450 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HEC95_RS09455 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HEC95_RS09460 ENOG4105VS8 Flagellar biosynthetic protein fliq HEC95_RS09465 ENOG4105CN7 Flagellar biosynthetic protein FliP HEC95_RS09470 ENOG4105K0P flagellar biosynthesis protein HEC95_RS09475 ENOG4105DD5 Flagellar motor switch protein HEC95_RS09480 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HEC95_RS09485 ENOG4107ZI8 flagellar basal body-associated protein flil HEC95_RS09490 ENOG4105WF4 Flagellar hook-length control protein HEC95_RS09495 ENOG4105GSA Flagellar export protein flij HEC95_RS09500 ENOG4108JIR Flagellum-specific ATP synthase HEC95_RS09505 ENOG41090PJ Flagellar assembly protein HEC95_RS09510 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HEC95_RS09515 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HEC95_RS09535 ENOG41066VF YeeE YedE family protein HEC95_RS09540 ENOG4105JCU Inherit from NOG: (Lipo)protein HEC95_RS09545 ENOG4105E5K Alpha-amylase HEC95_RS09555 ENOG4105MQ3 flagellar protein FliS HEC95_RS09560 ENOG4105DTS flagellar hook-associated HEC95_RS09575 ENOG4108C80 FliB family HEC95_RS09580 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HEC95_RS09585 ENOG4108M9K flagella biosynthesis protein FliZ HEC95_RS09590 ENOG4105EAB amino acid AbC transporter HEC95_RS09600 ENOG4105E5Q amino acid AbC transporter HEC95_RS09605 ENOG4105CDA abc transporter atp-binding protein HEC95_RS09610 ENOG4105VJY transcriptional regulator HEC95_RS09615 ENOG4105XVG cytoplasmic protein HEC95_RS09625 ENOG4105WH1 Two component transcriptional regulator luxr family HEC95_RS09670 ENOG4106RHG Yeca family HEC95_RS09675 ENOG4105E0U tyrosine-specific transport protein HEC95_RS09680 ENOG4105VVZ metal-binding protein HEC95_RS09685 ENOG41090A1 ferritin HEC95_RS09690 ENOG4105P23 (LipO)protein HEC95_RS09700 ENOG4108UEC Ferritin-like protein HEC95_RS09715 ENOG4108K4C ec 3.1.3.12 HEC95_RS09725 ENOG4108VA4 Universal stress protein HEC95_RS09735 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) HEC95_RS09740 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HEC95_RS09745 ENOG4107RD7 Flagellar Motor Protein, MotA HEC95_RS09750 ENOG4105ER2 Ompa motb domain protein HEC95_RS09755 ENOG4105CBS Chea signal transduction histidine kinase HEC95_RS09760 ENOG4108V3W Chemotaxis protein, CheW HEC95_RS09765 ENOG4105C8Q Methyl-accepting chemotaxis HEC95_RS09770 ENOG4105BZU Histidine kinase HEC95_RS09780 ENOG4108VYJ response regulator receiver protein HEC95_RS09785 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HEC95_RS09790 ENOG4105D00 flagellar biosynthetic protein flhB HEC95_RS09795 ENOG4105D7B Flagellar biosynthesis protein flha HEC95_RS09800 ENOG4105IRD Flagellar protein FlhE HEC95_RS09805 ENOG4105F5H Glycosyl Hydrolase Family 88 HEC95_RS09820 ENOG4106ZCM YecM protein HEC95_RS09840 ENOG4105WJG Glutathione HEC95_RS09845 ENOG41081XQ Conserved Protein HEC95_RS09850 ENOG4105D3W isochorismatase HEC95_RS09860 ENOG4108TIT dATP pyrophosphohydrolase HEC95_RS09865 ENOG4105CDY transcriptional regulatory protein HEC95_RS09875 ENOG4107S01 Repressor protein MetJ HEC95_RS09895 ENOG4105FAV ABC, transporter HEC95_RS09905 ENOG4105NXV High-affinity zinc uptake system protein HEC95_RS09910 ENOG4105DR5 peptidase HEC95_RS09915 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HEC95_RS09920 ENOG4105CA9 Pyruvate kinase HEC95_RS09925 ENOG4106KNT transcriptional regulator HEC95_RS09930 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HEC95_RS09935 ENOG4105C01 Dihydroxy-acid dehydratase HEC95_RS09940 ENOG4108UHU Aldolase HEC95_RS09950 ENOG4105X2V dna damage-inducible protein HEC95_RS09960 ENOG4108Q2J Inner membrane protein YebE HEC95_RS09965 ENOG4105CUG Oligopeptidase b HEC95_RS09970 ENOG4105UMD exodeoxyribonuclease X HEC95_RS09975 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HEC95_RS09980 ENOG4105MPK DNA polymerase III subunit theta HEC95_RS09985 ENOG4105FXM Copper resistance protein HEC95_RS09990 ENOG4108PNC copper resistance HEC95_RS09995 ENOG4105NKT exported protein HEC95_RS10010 ENOG4105EUZ Beta-lactamase domain protein HEC95_RS10065 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HEC95_RS10130 ENOG41076J9 exonuclease VIII HEC95_RS10140 ENOG4108YV9 Protein of unknown function (DUF2514) HEC95_RS10170 ENOG4105UZW Tail fiber assembly protein HEC95_RS10205 ENOG4105DWP Membrane HEC95_RS10230 ENOG4105VEV -acetyltransferase HEC95_RS10240 ENOG41064WM Uncharacterized protein YcgX HEC95_RS10245 ENOG4106EWC guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling HEC95_RS10255 ENOG4108R1E Serine threonine protein phosphatase 1 HEC95_RS10260 ENOG4105UVW uncharacterized protein yebW HEC95_RS10265 ENOG4105WT8 Protein of unknown function (DUF1480) HEC95_RS10275 ENOG4105DY2 Paraquat-inducible protein b HEC95_RS10280 ENOG4105H2K paraquat-inducible protein a HEC95_RS10285 ENOG4108ZGC gaf domain protein HEC95_RS10295 ENOG4105CN1 protease HEC95_RS10300 ENOG4105D0M Protease HtpX homolog HEC95_RS10305 ENOG4105C0R drug resistance transporter emrb qaca subfamily HEC95_RS10310 ENOG4105J4Q Transcriptional regulator HEC95_RS10320 ENOG4106CCY Protein MgrB homolog HEC95_RS10325 ENOG4105Q3Y exported protein HEC95_RS10340 ENOG4105CJN penicillin-binding protein HEC95_RS10345 ENOG4105DHI Methyltransferase HEC95_RS10360 ENOG4105F3R pts system mannose fructose sorbose family iid HEC95_RS10365 ENOG4105ETZ PTS System HEC95_RS10370 ENOG4105DAS pts system HEC95_RS10375 ENOG4105EE5 Membrane protein terC HEC95_RS10380 ENOG4107XTP (EAL) domain protein HEC95_RS10385 ENOG4105EJQ L-serine dehydratase HEC95_RS10395 ENOG4105CRQ synthase (Component I) HEC95_RS10400 ENOG4105X5C UPF0181 protein HEC95_RS10405 ENOG4105M4H endoribonuclease L-psp HEC95_RS10410 ENOG4105DVT helicase HEC95_RS10415 ENOG41072GX Peptidase M22 Glycoprotease HEC95_RS10420 ENOG4105Y4Z Outer Membrane Lipoprotein HEC95_RS10425 ENOG4105CEY Amp-dependent synthetase and ligase HEC95_RS10430 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HEC95_RS10440 ENOG4107QMS site-determining protein HEC95_RS10455 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HEC95_RS10470 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HEC95_RS10480 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) HEC95_RS10495 ENOG4105ED1 spovr family HEC95_RS10505 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HEC95_RS10515 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HEC95_RS10525 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HEC95_RS10540 ENOG4105D82 Glutamate dehydrogenase HEC95_RS10550 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HEC95_RS10555 ENOG4105C4M (Ubiquinol oxidase) subunit I HEC95_RS10560 ENOG4105MVP hydrogenase-1 operon protein HyaF HEC95_RS10565 ENOG4108VXY Hydrogenase-1 operon protein HyaE HEC95_RS10570 ENOG4108USZ hydrogenase HEC95_RS10575 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HEC95_RS10585 ENOG4105E3S small subunit HEC95_RS10600 ENOG4105C3G gtp-binding protein HEC95_RS10610 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HEC95_RS10615 ENOG4105CHH sulfate transporter HEC95_RS10620 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HEC95_RS10635 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) HEC95_RS10645 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HEC95_RS10650 ENOG4108YY7 Invasion gene expression up-regulator SirB HEC95_RS10655 ENOG41063JG Transcriptional regulator HEC95_RS10665 ENOG4105EWV Sodium calcium exchanger membrane region HEC95_RS10670 ENOG4105WS7 Cation transport regulator HEC95_RS10675 ENOG41090EX DsrE family HEC95_RS10680 ENOG4105ID0 Putative invasin HEC95_RS10685 ENOG4105WH1 Two component transcriptional regulator luxr family HEC95_RS10690 ENOG4105BZU Histidine kinase HEC95_RS10695 ENOG4105DQQ Major facilitator superfamily MFS_1 HEC95_RS10700 ENOG4105CRU nitrate reductase, alpha subunit HEC95_RS10705 ENOG4108IUE nitrate reductase beta subunit HEC95_RS10710 ENOG4105R3A Nitrate reductase HEC95_RS10715 ENOG41076YT nitrate reductase, gamma subunit HEC95_RS10760 ENOG4105CIY formyltetrahydrofolate deformylase HEC95_RS10770 ENOG4105D78 K07001 NTE family protein HEC95_RS10775 ENOG4105I93 response regulator HEC95_RS10780 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HEC95_RS10795 ENOG4105C0A alcohol dehydrogenase HEC95_RS10800 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HEC95_RS10805 ENOG4107QSI ABC, transporter HEC95_RS10810 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HEC95_RS10815 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HEC95_RS10820 ENOG4105C3U ABC transporter HEC95_RS10825 ENOG4108JQ7 (ABC) transporter HEC95_RS10830 ENOG4105EYW Ion transport protein HEC95_RS10850 ENOG4105K9H YciI-like protein HEC95_RS10855 ENOG410822N TonB family HEC95_RS10860 ENOG4105NAU thioesterase Superfamily protein HEC95_RS10875 ENOG4105PI0 Ferredoxin HEC95_RS10880 ENOG4105EIF outer membrane protein W HEC95_RS10885 ENOG4105WEF catalase HEC95_RS10890 ENOG4108N8X transition metal ion binding HEC95_RS10895 ENOG4108Z9Z response to DNA damage stimulus HEC95_RS10915 ENOG4105DK0 Indole-3-glycerol phosphate synthase HEC95_RS10920 ENOG4108EFP Anthranilate synthase component II HEC95_RS10925 ENOG4105CRQ synthase (Component I) HEC95_RS10935 ENOG4105DB7 PHP domain protein HEC95_RS10940 ENOG4107RTD sua5 ycio yrdc ywlc family protein HEC95_RS10945 ENOG4105FE9 pseudouridine synthase HEC95_RS10950 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HEC95_RS10955 ENOG4105UBK short-chain dehydrogenase reductase HEC95_RS10960 ENOG4105ERU peptidase HEC95_RS10965 ENOG4105RKX Protein of unknown function (DUF2498) HEC95_RS10970 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HEC95_RS10975 ENOG4107R11 Transcriptional regulator HEC95_RS10990 ENOG4107QM5 aconitate hydratase HEC95_RS10995 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) HEC95_RS11000 ENOG4105EYK Phosphatidylglycerophosphatase B HEC95_RS11005 ENOG4105Q4A inner membrane protein yciS HEC95_RS11010 ENOG4105CFV Tetratricopeptide repeat protein HEC95_RS11020 ENOG4108ZJT translation initiation factor, Sui1 HEC95_RS11025 ENOG41061RM osmotically inducible lipoprotein HEC95_RS11030 ENOG4105N2W Transcriptional regulator HEC95_RS11040 ENOG4105BZU Histidine kinase HEC95_RS11050 ENOG4105Q4T oxidoreductase HEC95_RS11055 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HEC95_RS11075 ENOG4108JQ2 peptide transport system atp-binding protein HEC95_RS11080 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HEC95_RS11085 ENOG4108EU3 peptide transport system, permease HEC95_RS11120 ENOG4107SKI cobyrinic Acid a,c-diamide synthase HEC95_RS11175 ENOG41073YN Protein of unknown function (DUF1380) HEC95_RS11420 ENOG4108EKA peptide transport system, permease HEC95_RS11425 ENOG4108J59 Extracellular solute-binding protein, family 5 HEC95_RS11430 ENOG4105E51 psp operon transcriptional activator HEC95_RS11435 ENOG41087YS Phage shock protein A HEC95_RS11440 ENOG4105YYT phage shock protein B HEC95_RS11445 ENOG4105FM1 phage shock protein C HEC95_RS11450 ENOG4105NNG Peripheral inner membrane phage-shock protein HEC95_RS11455 ENOG4105K8Z Phage shock protein HEC95_RS11460 ENOG4105CM6 amino acid regulated cytosolic protein HEC95_RS11470 ENOG4108JU8 Transcriptional regulator HEC95_RS11475 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HEC95_RS11480 ENOG4107S8C mandelate racemase muconate lactonizing HEC95_RS11485 ENOG4105KXI murein peptide amidase A HEC95_RS11490 ENOG4107QSI ABC, transporter HEC95_RS11500 ENOG4105HEI LysR family (Transcriptional regulator HEC95_RS11505 ENOG4105CV8 reductase HEC95_RS11510 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HEC95_RS11515 ENOG4108XFH Transcriptional regulator HEC95_RS11530 ENOG4106PHM regulatory protein HEC95_RS11550 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HEC95_RS11570 ENOG4105D64 Mechanosensitive ion channel HEC95_RS11575 ENOG4105S5I Membrane HEC95_RS11580 ENOG4105Q9Y Universal stress protein HEC95_RS11585 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HEC95_RS11590 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HEC95_RS11595 ENOG4108DG9 Smr protein MutS2 HEC95_RS11600 ENOG4105C8Q Methyl-accepting chemotaxis HEC95_RS11610 ENOG4105C1J atp-dependent rna helicase HEC95_RS11675 ENOG4105WI6 cell killing protein encoded within cryptic prophage HEC95_RS11690 ENOG4105RWQ Protein of unknown function (DUF1364) HEC95_RS11730 ENOG410814C multidrug resistance protein HEC95_RS11735 ENOG4108RW8 Universal stress protein F HEC95_RS11740 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HEC95_RS11750 ENOG4105IKK cytoplasmic protein HEC95_RS11755 ENOG41090X5 Heat shock protein hslJ HEC95_RS11760 ENOG4105C5I Dehydrogenase HEC95_RS11765 ENOG4107H52 Dicarboxylate transport HEC95_RS11770 ENOG410689M (LipO)protein HEC95_RS11775 ENOG4105WXT Conserved Protein HEC95_RS11790 ENOG4105CQ7 ATP-dependent helicase HEC95_RS11795 ENOG4107DB1 DUF218 domain HEC95_RS11800 ENOG4105CPW cytochrome b561 HEC95_RS11805 ENOG4108WF3 methyltransferase HEC95_RS11815 ENOG4105E5Q amino acid AbC transporter HEC95_RS11825 ENOG4105E5Q amino acid AbC transporter HEC95_RS11830 ENOG4107R0W ABC transporter HEC95_RS11840 ENOG4107ZUJ lipid metabolic process HEC95_RS11865 ENOG4105C8Q Methyl-accepting chemotaxis HEC95_RS11870 ENOG4105DDW LysR family Transcriptional regulator HEC95_RS11875 ENOG4105E32 cytoplasmic protein HEC95_RS11880 ENOG4105EBR Carboxylesterase HEC95_RS11890 ENOG4108YYC ycei family HEC95_RS11900 ENOG4105CPQ Dehydrogenase HEC95_RS11905 ENOG4105DJB Major Facilitator Superfamily HEC95_RS11910 ENOG4105CHR reductase HEC95_RS11925 ENOG4108PQ7 sgc region transcriptional regulator HEC95_RS11930 ENOG4108RK0 3-epimerase HEC95_RS11935 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HEC95_RS11940 ENOG4106P19 photosystem i assembly btpa HEC95_RS11945 ENOG4105DT3 PTS system, galactitol-specific IIc component HEC95_RS11950 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HEC95_RS11955 ENOG4105CN9 Peptidase m42 family protein HEC95_RS11960 ENOG4108Z9I -acetyltransferase HEC95_RS11965 ENOG4107WE3 acetyltransferase YdcK HEC95_RS11970 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HEC95_RS11975 ENOG41088CC tellurite resistance protein tehB HEC95_RS11980 ENOG4108KKZ (LipO)protein HEC95_RS11985 ENOG4105DKK Benzoate HEC95_RS11990 ENOG4108JCI Transcriptional regulator HEC95_RS11995 ENOG4105CFP Peptidase U32 HEC95_RS12000 ENOG4105RR0 Protein of unknown function (DUF2554) HEC95_RS12020 ENOG4108UQS dipeptidase HEC95_RS12025 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HEC95_RS12040 ENOG410654E Membrane HEC95_RS12060 ENOG4105R71 cytoplasmic protein HEC95_RS12065 ENOG4108T9Y Inner membrane protein ydcZ HEC95_RS12070 ENOG4108Z7F N-acetyltransferase HEC95_RS12075 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein HEC95_RS12080 ENOG4108WYP Transcriptional regulator HEC95_RS12085 ENOG4105CHB tonB-dependent Receptor HEC95_RS12090 ENOG4108NS2 receptor HEC95_RS12095 ENOG4105SUV lipoprotein YgdR HEC95_RS12100 ENOG4105C85 amino acid HEC95_RS12110 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HEC95_RS12115 ENOG4105JAB phenazine biosynthesis protein, phzf family HEC95_RS12120 ENOG4105D0D Nitrate reductase 2, gamma subunit HEC95_RS12125 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HEC95_RS12130 ENOG4108IUE nitrate reductase beta subunit HEC95_RS12135 ENOG4105CRU nitrate reductase, alpha subunit HEC95_RS12140 ENOG4107QND Nitrite extrusion protein HEC95_RS12175 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HEC95_RS12180 ENOG4108MG3 formate dehydrogenase HEC95_RS12185 ENOG4105DQ4 alcohol dehydrogenase HEC95_RS12200 ENOG4105TPS biofilm-dependent modulation protein HEC95_RS12205 ENOG4108Z9K Osmotically inducible protein HEC95_RS12210 ENOG4105XXV Acid-resistance protein HEC95_RS12220 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) HEC95_RS12235 ENOG4105C87 Aminotransferase class I and II HEC95_RS12240 ENOG4105DFD Na H antiporter HEC95_RS12245 ENOG41060NJ transcriptional regulator HEC95_RS12260 ENOG4108UQ8 endoribonuclease L-psp HEC95_RS12265 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) HEC95_RS12290 ENOG4108I5G Major Facilitator superfamily HEC95_RS12295 ENOG4105CPQ Dehydrogenase HEC95_RS12300 ENOG4105C6F GntR Family Transcriptional Regulator HEC95_RS12315 ENOG4105DPX Hydrogenase, large subunit HEC95_RS12320 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HEC95_RS12340 ENOG4105MVP hydrogenase-1 operon protein HyaF HEC95_RS12365 ENOG4105FFC UPF0187 protein HEC95_RS12370 ENOG4105M0C cytoplasmic protein HEC95_RS12380 ENOG4105C26 Dehydrogenase HEC95_RS12385 ENOG4105EGI Transcriptional regulator HEC95_RS12400 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HEC95_RS12405 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HEC95_RS12410 ENOG4106DNR multiple antibiotic resistance protein HEC95_RS12415 ENOG4108594 Permease of the drug metabolite transporter HEC95_RS12420 ENOG4105E5W Transporter HEC95_RS12430 ENOG4108YDI single-species biofilm formation on inanimate substrate HEC95_RS12435 ENOG4108WTK competence damage-inducible protein HEC95_RS12445 ENOG4105DGW oligopeptidase A HEC95_RS12450 ENOG4105EMU Dehydrogenase HEC95_RS12455 ENOG4107XBN GntR Family Transcriptional Regulator HEC95_RS12460 ENOG41061EV selenium-binding protein YdfZ HEC95_RS12465 ENOG4105DEI Mannitol dehydrogenase HEC95_RS12475 ENOG4105CPQ Dehydrogenase HEC95_RS12495 ENOG4108MK9 spermidine N(1)-acetyltransferase HEC95_RS12505 ENOG4105KBG Protein of unknown function (DUF1161) HEC95_RS12510 ENOG4107QY8 reductase HEC95_RS12515 ENOG4105C3J Cysteine desulfurase HEC95_RS12520 ENOG4105QAX Iron-sulfur HEC95_RS12525 ENOG4107KGK dmso reductase anchor subunit HEC95_RS12530 ENOG4108NEM leader-binding protein dmsD HEC95_RS12535 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component HEC95_RS12540 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HEC95_RS12545 ENOG4105E90 ABC transporter HEC95_RS12550 ENOG4108IJ8 ABC transporter HEC95_RS12560 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HEC95_RS12565 ENOG4105DAG ROK family HEC95_RS12570 ENOG4106NZI LysR family Transcriptional regulator HEC95_RS12575 ENOG4105D94 Major Facilitator Superfamily HEC95_RS12585 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HEC95_RS12600 ENOG4105DSF transport protein HEC95_RS12605 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HEC95_RS12610 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HEC95_RS12615 ENOG4105C5D exported protein HEC95_RS12620 ENOG4105D5Q Arginine ornithine antiporter HEC95_RS12625 ENOG4105RA2 Membrane HEC95_RS12630 ENOG4107EXC regulatoR HEC95_RS12635 ENOG4105FCK Membrane HEC95_RS12640 ENOG4105CPN adenine deaminase HEC95_RS12645 ENOG4105JJR Histidine kinase HEC95_RS12655 ENOG4105C9Q fumarate hydratase class II HEC95_RS12660 ENOG4107GFK fumarate HEC95_RS12665 ENOG4105EIP mannose-6-phosphate isomerase HEC95_RS12670 ENOG4106J39 exported protein HEC95_RS12690 ENOG4105D9R oxidoreductase HEC95_RS12695 ENOG4106C6R beta-lactam resistance protein HEC95_RS12705 ENOG4105M9B inner membrane protein ydgK HEC95_RS12730 ENOG4108UQQ Electron transport complex HEC95_RS12740 ENOG4105CSM endonuclease III HEC95_RS12745 ENOG4105DUX Transporter HEC95_RS12750 ENOG4108K3A Glutathione S-transferase HEC95_RS12770 ENOG410642K Lysozyme inhibitor HEC95_RS12780 ENOG4108XTF Outer Membrane Lipoprotein HEC95_RS12795 ENOG4105Y49 secretion protein, HlyD family HEC95_RS12800 ENOG4105DSW Fusaric acid resistance protein HEC95_RS12805 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HEC95_RS12810 ENOG4107RGM aldo keto reductase HEC95_RS12815 ENOG4105XZD Fe-S protein HEC95_RS12820 ENOG4108WUH Transcriptional regulator, TetR family HEC95_RS12825 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HEC95_RS12830 ENOG4108UYE Lactoylglutathione lyase HEC95_RS12835 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) HEC95_RS12840 ENOG4105M2J Glutaredoxin HEC95_RS12845 ENOG4105K4H Nlp p60 protein HEC95_RS12850 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HEC95_RS12865 ENOG4105F52 Transcriptional regulator HEC95_RS12870 ENOG4105CZQ inner membrane transport protein YdhC HEC95_RS12875 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HEC95_RS12880 ENOG4108R6K riboflavin synthase, subunit alpha HEC95_RS12900 ENOG4108IUF type iii secretion HEC95_RS12905 ENOG4108TN6 type iii secretion HEC95_RS12910 ENOG41083GP type iii secretion HEC95_RS12915 ENOG4108HHI Type III secretion system protein HEC95_RS12920 ENOG41063Q7 Type III secretion system protein HEC95_RS12935 ENOG4108JIR Flagellum-specific ATP synthase HEC95_RS12945 ENOG4106H1D secretion system apparatus protein HEC95_RS12950 ENOG4105UQF type iii secretion HEC95_RS12955 ENOG4106563 type III secretion system apparatus protein HEC95_RS13005 ENOG4106FZW pathogenicity island effector protein HEC95_RS13010 ENOG4108SZ7 secretion system effector HEC95_RS13020 ENOG4105ZQI secreted protein HEC95_RS13050 ENOG4105BZU Histidine kinase HEC95_RS13060 ENOG4108XDN Transcriptional regulator HEC95_RS13065 ENOG4107SEY Conserved Protein HEC95_RS13070 ENOG4105RFR Protein of unknown function (DUF2767) HEC95_RS13075 ENOG4108ZXC Two component transcriptional regulator, luxr family HEC95_RS13080 ENOG4106AFQ Histidine kinase HEC95_RS13085 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HEC95_RS13090 ENOG4106WHD Tetrathionate reductase HEC95_RS13095 ENOG4105DB1 molybdopterin oxidoreductase HEC95_RS13100 ENOG4108RVA ribokinase HEC95_RS13110 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) HEC95_RS13115 ENOG4105CUB amino acid HEC95_RS13120 ENOG4105CA9 Pyruvate kinase HEC95_RS13135 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HEC95_RS13150 ENOG4105JRK feS assembly protein SufD HEC95_RS13155 ENOG4105C3K feS assembly ATPase SufC HEC95_RS13160 ENOG4105DIW FeS assembly protein SUFB HEC95_RS13165 ENOG4108Z4V iron-sulfur cluster assembly HEC95_RS13170 ENOG4108ETY sodium dicarboxylate symporter HEC95_RS13175 ENOG410671Z uncharacterized protein ydiH HEC95_RS13180 ENOG4105KA0 thioesterase Superfamily protein HEC95_RS13185 ENOG4105CQB FAD linked oxidase domain protein HEC95_RS13190 ENOG4105IPI Membrane HEC95_RS13200 ENOG4105SUA Ydil protein HEC95_RS13205 ENOG4105EMV Major Facilitator HEC95_RS13210 ENOG4105EMV Major Facilitator HEC95_RS13225 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HEC95_RS13230 ENOG4105C1G acyl-Coa dehydrogenase HEC95_RS13235 ENOG4105W4W Transcriptional regulator HEC95_RS13240 ENOG4105CV7 Electron transfer flavoprotein HEC95_RS13245 ENOG4105C10 Electron transfer flavoprotein HEC95_RS13250 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HEC95_RS13255 ENOG41090P5 ferredoxin-like protein HEC95_RS13260 ENOG4105CEY Amp-dependent synthetase and ligase HEC95_RS13265 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HEC95_RS13275 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HEC95_RS13295 ENOG4108QBX (LipO)protein HEC95_RS13305 ENOG4108V06 Glutathione peroxidase HEC95_RS13315 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) HEC95_RS13320 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) HEC95_RS13340 ENOG41082NX 50s ribosomal protein l35 HEC95_RS13345 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HEC95_RS13355 ENOG4105K25 O-Antigen polymerase HEC95_RS13380 ENOG4108NE3 Salt-induced outer membrane protein HEC95_RS13385 ENOG4105DE4 1-phosphofructokinase HEC95_RS13390 ENOG4105P10 Uncharacterized protein ydiZ HEC95_RS13400 ENOG4107PN8 YfeABCD locus regulator HEC95_RS13405 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HEC95_RS13410 ENOG4107K5X Membrane-bound metal-dependent hydrolase HEC95_RS13415 ENOG4108ETY sodium dicarboxylate symporter HEC95_RS13425 ENOG4105CH6 catalase HEC95_RS13435 ENOG4105F8D glycoside hydrolase family 4 HEC95_RS13440 ENOG4105EZV Transcriptional regulator HEC95_RS13445 ENOG4105VCP PTS System HEC95_RS13450 ENOG4105CK1 PTS System HEC95_RS13455 ENOG4105VZJ PTS System HEC95_RS13460 ENOG4105KKI DNA-binding transcriptional activator OsmE HEC95_RS13470 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HEC95_RS13475 ENOG4108SPG Periplasmic Protein HEC95_RS13505 ENOG4105CGK Exodeoxyribonuclease III HEC95_RS13510 ENOG4105M6F mutator MutT protein HEC95_RS13515 ENOG4105MTM Protein of unknown function (DUF1496) HEC95_RS13520 ENOG4105D82 Glutamate dehydrogenase HEC95_RS13525 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HEC95_RS13530 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) HEC95_RS13535 ENOG41069NU Nitroreductase HEC95_RS13540 ENOG4105D07 Signal peptide peptidase, SppA HEC95_RS13545 ENOG4105HDK L-asparaginase HEC95_RS13550 ENOG4108RWI nicotinamidase HEC95_RS13555 ENOG4108KUU Inner membrane metabolite transport protein ydjE HEC95_RS13560 ENOG4105E98 transcriptional regulator DeoR family HEC95_RS13565 ENOG4105CPC Aldo Keto reductase HEC95_RS13570 ENOG4107UH8 sugar kinase HEC95_RS13575 ENOG4105D2N Aldolase HEC95_RS13580 ENOG4105CPQ Dehydrogenase HEC95_RS13585 ENOG4107TE1 transport protein HEC95_RS13595 ENOG4105VUT cytoplasmic protein HEC95_RS13605 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HEC95_RS13610 ENOG4105DSB aldose 1-epimerase HEC95_RS13615 ENOG4105CV8 reductase HEC95_RS13620 ENOG4105C4X radical SAM domain protein HEC95_RS13625 ENOG4105GNX MltA-interacting MipA family protein HEC95_RS13630 ENOG4105CYN Serine protein kinase HEC95_RS13645 ENOG4108KHP Diguanylate cyclase HEC95_RS13650 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HEC95_RS13665 ENOG4105R1U AraC Family Transcriptional Regulator HEC95_RS13670 ENOG4105DJ2 Major Facilitator Superfamily HEC95_RS13675 ENOG4105K78 MarR family Transcriptional regulator HEC95_RS13685 ENOG4105UCG Domain of unknown function (DUF333) HEC95_RS13690 ENOG4106G4W HEC95_RS13695 ENOG4105Y3U Transglycosylase-associated protein HEC95_RS13705 ENOG4105YP6 Domain of unknown function (DUF1869) HEC95_RS13710 ENOG4108YS1 cytoplasmic protein HEC95_RS13720 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) HEC95_RS13730 ENOG4108Z6Z Transcriptional regulator HEC95_RS13745 ENOG4108MEK Metal-binding protein YodA HEC95_RS13760 ENOG4105D64 Mechanosensitive ion channel HEC95_RS13765 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HEC95_RS13770 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HEC95_RS13780 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HEC95_RS13795 ENOG4108VKM cytochrome b561 HEC95_RS13805 ENOG4108ZNX Heat shock protein HEC95_RS13825 ENOG4105H38 Membrane HEC95_RS13835 ENOG41060EU Cold shock-like protein HEC95_RS13840 ENOG4106F2Y RICIN HEC95_RS13845 ENOG4105Y50 Virulence Protein HEC95_RS13860 ENOG4108HMX isocitrate dehydrogenase (NADP) HEC95_RS13865 ENOG4108R99 pseudouridine synthase HEC95_RS13890 ENOG4107QTF adenylosuccinate lyase HEC95_RS13905 ENOG4105EZE Cupin 4 family protein HEC95_RS13920 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HEC95_RS13935 ENOG4105D38 putrescine abc transporter HEC95_RS13940 ENOG4108HM4 ABC transporter HEC95_RS13945 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HEC95_RS13955 ENOG4105D60 lipoprotein releasing system transmembrane protein HEC95_RS13960 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HEC95_RS13965 ENOG4105D60 lipoprotein releasing system transmembrane protein HEC95_RS13970 ENOG4108JA2 transcriptioN-repair coupling factor HEC95_RS13975 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HEC95_RS13980 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HEC95_RS13985 ENOG4108IND Tetr family transcriptional regulator HEC95_RS13990 ENOG4107MBR 17 kDa surface antigen HEC95_RS13995 ENOG4105CEP NADH dehydrogenase HEC95_RS14015 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HEC95_RS14020 ENOG41090DQ Lipoprotein HEC95_RS14025 ENOG4105K59 histidine triad (HIT) protein HEC95_RS14030 ENOG4105CNM Receptor HEC95_RS14035 ENOG4105CI1 PTS System HEC95_RS14040 ENOG4105F8V Hydrolase, tatD family HEC95_RS14045 ENOG4107QRG dna polymerase iii HEC95_RS14055 ENOG4105HHA aminodeoxychorismate lyase HEC95_RS14060 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HEC95_RS14065 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HEC95_RS14070 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HEC95_RS14075 ENOG4105CHR reductase HEC95_RS14080 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HEC95_RS14100 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HEC95_RS14105 ENOG4108UHJ MAF-like protein HEC95_RS14120 ENOG4105EI2 Pseudouridine synthase HEC95_RS14125 ENOG4107QQB Ribonuclease E HEC95_RS14130 ENOG4105DTJ flagellar hook-associated protein HEC95_RS14135 ENOG4105E1Q flagellar hook-associated protein HEC95_RS14140 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HEC95_RS14155 ENOG4105CGA flagellar basal-body rod protein FlgG HEC95_RS14160 ENOG4108KPB Flagellar basal-body rod protein FlgF HEC95_RS14165 ENOG4105BZE flagellar hook protein, FlgE HEC95_RS14170 ENOG4105W00 Flagellar hook capping protein HEC95_RS14175 ENOG4108ZC9 flagellar basal-body rod protein flgc HEC95_RS14180 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HEC95_RS14185 ENOG4105CKS Flagella basal body P-ring formation protein flgA HEC95_RS14190 ENOG4105M9M anti-sigma28 factor FlgM HEC95_RS14195 ENOG4105QVD Flagella synthesis protein FlgN HEC95_RS14200 ENOG4105CJR Integral membrane protein (MviN HEC95_RS14205 ENOG4105EP9 oxidoreductase HEC95_RS14215 ENOG4105D9U N-acetyltransferase HEC95_RS14225 ENOG4105E9S glutaredoxin 2 HEC95_RS14230 ENOG4105F3T (LipO)protein HEC95_RS14240 ENOG4105MEA DNA damage-inducible protein i HEC95_RS14245 ENOG4105PVA Biofilm formation regulatory protein BssS HEC95_RS14255 ENOG4106974 biofilm formation HEC95_RS14260 ENOG4105DS1 cytochrome b561 HEC95_RS14265 ENOG4108YYC ycei family HEC95_RS14275 ENOG4105D1S lipid A biosynthesis HEC95_RS14285 ENOG4108W47 Acidic protein msyB HEC95_RS14290 ENOG4105NAC (LipO)protein HEC95_RS14295 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HEC95_RS14310 ENOG4107RZC phospholipase d HEC95_RS14315 ENOG4108UVJ appr-1-p processing domain protein HEC95_RS14320 ENOG41068SS HEC95_RS14325 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) HEC95_RS14330 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HEC95_RS14335 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HEC95_RS14340 ENOG41086KC Transcriptional regulator HEC95_RS14345 ENOG4108XDW curli assembly protein CsgE HEC95_RS14350 ENOG4108WYR Curli production assembly transport component, CsgF HEC95_RS14355 ENOG4105P8Q Curli production assembly transport component CsgG HEC95_RS14360 ENOG4108UQ5 membrane protein YcdZ HEC95_RS14365 ENOG4107XHZ cytoplasmic chaperone TorD family protein HEC95_RS14400 ENOG4105EQR Transposase IS116 IS110 IS902 HEC95_RS14420 ENOG4108C33 Resolvase HEC95_RS14430 ENOG4105UZW Tail fiber assembly protein HEC95_RS14435 ENOG4105Y9F tail fiber protein HEC95_RS14440 ENOG4105Y0G tail protein HEC95_RS14445 ENOG4108T86 baseplate J family protein HEC95_RS14485 ENOG4105TKZ Tail Sheath HEC95_RS14535 ENOG4105CAR Terminase, large subunit HEC95_RS14550 ENOG4108YV9 Protein of unknown function (DUF2514) HEC95_RS14555 ENOG4105NVB glycoside hydrolase, family 19 HEC95_RS14580 ENOG4105HGD Antitermination protein HEC95_RS14585 ENOG4108MXB Protein of unknown function (DUF968) HEC95_RS14595 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HEC95_RS14600 ENOG4105DFE Dna adenine methylase HEC95_RS14620 ENOG4106050 phage regulatory protein, rha family HEC95_RS14625 ENOG4108S1U HEC95_RS14640 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) HEC95_RS14655 ENOG4108R7K Metal Dependent Phosphohydrolase HEC95_RS14830 ENOG4108YX2 DNA-binding protein HEC95_RS14900 ENOG4105FYV Amp nucleosidase HEC95_RS14925 ENOG4105UQX Mate efflux family protein HEC95_RS14935 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HEC95_RS14950 ENOG4108YZT Adenosylcobinamide kinase HEC95_RS14960 ENOG4108JJB ABC transporter HEC95_RS14965 ENOG4108V4M Cobalt abc transporter HEC95_RS14970 ENOG4105W4R Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) HEC95_RS14975 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) HEC95_RS14980 ENOG4105DVK Precorrin-2 c20-methyltransferase HEC95_RS14985 ENOG4107PPM cobalt chelatase HEC95_RS14990 ENOG4105QUC reductase HEC95_RS14995 ENOG4105E4R Precorrin-3B C17-methyltransferase HEC95_RS15000 ENOG4108P62 biosynthesis protein (CbiG) HEC95_RS15005 ENOG4105CIA precorrin-4 C(11)-methyltransferase HEC95_RS15010 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase HEC95_RS15015 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase HEC95_RS15025 ENOG41081F0 Precorrin-8x methylmutase HEC95_RS15035 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) HEC95_RS15040 ENOG4107XVH Transcriptional regulator HEC95_RS15045 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HEC95_RS15050 ENOG4105KNY Microcompartments protein HEC95_RS15055 ENOG4105EHR propanediol utilization protein pduB HEC95_RS15060 ENOG4105DMB glycerol dehydratase HEC95_RS15065 ENOG4105YCI dehydratase medium subunit HEC95_RS15070 ENOG4108ZFT Dehydratase small subunit HEC95_RS15075 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit HEC95_RS15085 ENOG4105KNY Microcompartments protein HEC95_RS15095 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) HEC95_RS15105 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HEC95_RS15115 ENOG4108EKI Dehydrogenase HEC95_RS15120 ENOG4105C0A alcohol dehydrogenase HEC95_RS15125 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) HEC95_RS15135 ENOG4105M3W utilization protein HEC95_RS15140 ENOG4105KTW ethanolamine utilization protein HEC95_RS15145 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HEC95_RS15150 ENOG4105JZC GHMP kinase HEC95_RS15155 ENOG41090HJ UPF0265 protein HEC95_RS15160 ENOG4105DR8 Membrane HEC95_RS15165 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) HEC95_RS15170 ENOG4105DZ1 carboxypeptidase HEC95_RS15175 ENOG4108NWD Cytochrome HEC95_RS15180 ENOG4105QAX Iron-sulfur HEC95_RS15185 ENOG4108J2R molybdopterin oxidoreductase HEC95_RS15200 ENOG4105CJB Exodeoxyribonuclease I HEC95_RS15205 ENOG4105CUB amino acid HEC95_RS15215 ENOG4105EQ1 Transcriptional regulator HEC95_RS15220 ENOG4107SRH Nad-dependent epimerase dehydratase HEC95_RS15245 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HEC95_RS15250 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HEC95_RS15265 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase HEC95_RS15270 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HEC95_RS15275 ENOG4105C6Y Udp-glucose 6-dehydrogenase HEC95_RS15280 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HEC95_RS15285 ENOG4105D3Q Sugar transferase HEC95_RS15290 ENOG4106ECQ phosphomannomutase HEC95_RS15295 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HEC95_RS15300 ENOG4108KBE Glycosyl transferase, family 2 HEC95_RS15305 ENOG4108TJN glycosyl transferase group 1 HEC95_RS15310 ENOG4107YYJ Glycosyl transferase, family 2 HEC95_RS15315 ENOG41081E6 Inherit from COG: Polysaccharide biosynthesis protein HEC95_RS15320 ENOG4108IAJ Nad-dependent epimerase dehydratase HEC95_RS15325 ENOG4108SMP Nad-dependent epimerase dehydratase HEC95_RS15330 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HEC95_RS15335 ENOG4105FAW cDP-glucose 4,6-dehydratase HEC95_RS15340 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase HEC95_RS15345 ENOG4107QK7 reductase HEC95_RS15350 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase HEC95_RS15355 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HEC95_RS15360 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase HEC95_RS15365 ENOG4105C1B dTDP-glucose 4-6-dehydratase HEC95_RS15370 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HEC95_RS15375 ENOG4105G1A colanic acid biosynthesis protein HEC95_RS15380 ENOG4107T8Q Glycosyl transferase (Group 1 HEC95_RS15385 ENOG4105C74 pyruvyl transferase HEC95_RS15390 ENOG4105PSV Polysaccharide Biosynthesis Protein HEC95_RS15395 ENOG4105D3Q Sugar transferase HEC95_RS15400 ENOG4107QKV phosphomannomutase HEC95_RS15405 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HEC95_RS15410 ENOG4106CD9 glycosyl transferase group 1 HEC95_RS15415 ENOG4105FGF GDP-mannose mannosyl hydrolase HEC95_RS15420 ENOG4105C30 Nad-dependent epimerase dehydratase HEC95_RS15425 ENOG4105C0K Gdp-mannose 4,6-dehydratase HEC95_RS15430 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HEC95_RS15435 ENOG4105ECJ Glycosyl Transferase HEC95_RS15440 ENOG4108NYJ Colanic acid HEC95_RS15445 ENOG4107RXY Glycosyl transferase HEC95_RS15450 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HEC95_RS15455 ENOG41090RK glycosyl transferase HEC95_RS15460 ENOG4105D75 Capsular exopolysaccharide family HEC95_RS15465 ENOG4105KJF protein tyrosine phosphatase HEC95_RS15470 ENOG4105DAY polysaccharide export protein HEC95_RS15475 ENOG4105EE5 Membrane protein terC HEC95_RS15480 ENOG4108GAE asmA family HEC95_RS15495 ENOG4105BZU Histidine kinase HEC95_RS15500 ENOG4105D03 DNA-3-methyladenine glycosylase II HEC95_RS15505 ENOG4105R8A Heat shock protein HEC95_RS15535 ENOG4105EB3 Histidine kinase HEC95_RS15540 ENOG4105E3W Two component transcriptional regulator (Winged helix family HEC95_RS15560 ENOG4105CFP Peptidase U32 HEC95_RS15570 ENOG41090V3 Tir chaperone protein (CesT) family HEC95_RS15585 ENOG4105EIE fructose-bisphosphate aldolase HEC95_RS15590 ENOG4105EAA nucleoside HEC95_RS15595 ENOG4108KD5 ADP-ribosylation crystallin J1 HEC95_RS15600 ENOG4108TFM Kinase, PfkB family HEC95_RS15605 ENOG4105FDP GntR family transcriptional regulator HEC95_RS15610 ENOG4105DWF phosphomethylpyrimidine kinase HEC95_RS15620 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HEC95_RS15625 ENOG410662B Type-1 fimbrial protein HEC95_RS15630 ENOG4105CW0 outer membrane usher protein HEC95_RS15635 ENOG4108MQF Chaperone HEC95_RS15650 ENOG4105D1F ATP-binding protein HEC95_RS15660 ENOG4108YCW (LipO)protein HEC95_RS15670 ENOG4108W15 Protein of unknown function (DUF1456) HEC95_RS15675 ENOG4108NEV two component transcriptional regulator, LytTR family HEC95_RS15680 ENOG4108HRK Histidine kinase HEC95_RS15695 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HEC95_RS15700 ENOG4108IJ8 ABC transporter HEC95_RS15705 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HEC95_RS15710 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HEC95_RS15715 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HEC95_RS15720 ENOG4105CXG d-lactate dehydrogenase HEC95_RS15725 ENOG41061WM D-Alanyl-D-Alanine HEC95_RS15730 ENOG41069YE inner membrane protein yohC HEC95_RS15735 ENOG4105KHU inner membrane protein YohD HEC95_RS15740 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HEC95_RS15745 ENOG4105ETP RND efflux system, outer membrane lipoprotein HEC95_RS15755 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HEC95_RS15760 ENOG4105MSY salicylate hydroxylase HEC95_RS15765 ENOG4108RXX maleylacetoacetate isomerase HEC95_RS15795 ENOG41067MG lrgb family HEC95_RS15805 ENOG4107GZ4 SanA protein HEC95_RS15810 ENOG4105Y9N Membrane HEC95_RS15815 ENOG4105BZ8 glutamate synthase HEC95_RS15820 ENOG4107SJI Dehydrogenase HEC95_RS15825 ENOG4107SDZ Galactoside transport system permease protein mglC HEC95_RS15830 ENOG4105C2J ABC transporter HEC95_RS15835 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HEC95_RS15840 ENOG41060NJ transcriptional regulator HEC95_RS15845 ENOG4105DHF Membrane HEC95_RS15850 ENOG4105EUJ GTP cyclohydrolase i HEC95_RS15865 ENOG4105EJQ L-serine dehydratase HEC95_RS15870 ENOG4105EAC phosphoserine phosphatase HEC95_RS15875 ENOG4105CXY transporter HEC95_RS15880 ENOG4105D05 Receptor HEC95_RS15885 ENOG4108IQI permease HEC95_RS15890 ENOG4105DUM transcriptional regulator, lysR family HEC95_RS15895 ENOG4105HMI Membrane HEC95_RS15905 ENOG4105DM4 PTS System HEC95_RS15910 ENOG4105DE4 1-phosphofructokinase HEC95_RS15915 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HEC95_RS15920 ENOG4105S8Q sugar efflux transporter HEC95_RS15935 ENOG4105KRS Proteinase inhibitor HEC95_RS15940 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) HEC95_RS15945 ENOG4105CKI cobalamin synthesis protein HEC95_RS15950 ENOG41076MN Phosphoesterase, PA-phosphatase related HEC95_RS15955 ENOG4107TT5 NLP P60 protein HEC95_RS15960 ENOG4105CXC rtn protein HEC95_RS15965 ENOG4105E43 Extracellular solute-binding protein, family 5 HEC95_RS15970 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HEC95_RS15975 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HEC95_RS15980 ENOG4108JQ5 ABC transporter HEC95_RS15985 ENOG4105HG6 HEC95_RS15990 ENOG4105C2C drug resistance transporter, Bcr CflA HEC95_RS15995 ENOG4105I08 Pseudouridine synthase HEC95_RS16000 ENOG4105CFI type iii restriction protein res subunit HEC95_RS16025 ENOG4105E68 Sulfatase HEC95_RS16070 ENOG4105WH1 Two component transcriptional regulator luxr family HEC95_RS16075 ENOG4105KWW Biogenesis protein HEC95_RS16080 ENOG4107QX9 Thiol disulfide interChange protein HEC95_RS16085 ENOG4105DA4 cytochrome c-type biogenesis protein HEC95_RS16095 ENOG4105X3C heme exporter protein HEC95_RS16100 ENOG41060IM Heme exporter protein HEC95_RS16105 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HEC95_RS16110 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HEC95_RS16115 ENOG4105CUW cytochrome C-TYPE protein HEC95_RS16120 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HEC95_RS16125 ENOG4105GXZ Ferredoxin-type protein NapH HEC95_RS16130 ENOG4108BGM Quinol dehydrogenase periplasmic component HEC95_RS16140 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HEC95_RS16145 ENOG4108ZNS ferredoxin-type protein NapF HEC95_RS16155 ENOG4105IBP Cyclic peptide transporter HEC95_RS16160 ENOG4105CF1 Alkylated DNA repair protein HEC95_RS16165 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HEC95_RS16170 ENOG4105CJ2 (LipO)protein HEC95_RS16175 ENOG4105FCK Membrane HEC95_RS16180 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HEC95_RS16185 ENOG41068CG regulatoR HEC95_RS16190 ENOG4105BZU Histidine kinase HEC95_RS16195 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HEC95_RS16200 ENOG4105CXK mandelate racemase muconate lactonizing HEC95_RS16220 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HEC95_RS16225 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HEC95_RS16230 ENOG4105XPH Ferredoxin HEC95_RS16235 ENOG4105CZM Major Facilitator HEC95_RS16240 ENOG4105GZI Transcriptional regulator HEC95_RS16245 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HEC95_RS16250 ENOG4105CXY transporter HEC95_RS16255 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HEC95_RS16265 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HEC95_RS16295 ENOG4107258 Transcriptional regulator HEC95_RS16300 ENOG4108EWA cinA-like protein HEC95_RS16305 ENOG4108UII YfaZ family HEC95_RS16355 ENOG4106GZG polymyxin resistance protein B HEC95_RS16360 ENOG4105CEY Amp-dependent synthetase and ligase HEC95_RS16370 ENOG4108IPT Naphthoate synthase HEC95_RS16385 ENOG4105E4F Isochorismate synthase HEC95_RS16390 ENOG4105TNS Conserved Protein HEC95_RS16395 ENOG4107YB6 acetyltransferase, (GNAT) family HEC95_RS16410 ENOG4105CP2 von willebrand factor, type a HEC95_RS16425 ENOG4105C8S subunit m HEC95_RS16430 ENOG4105D65 subunit l HEC95_RS16440 ENOG4107UFS subunit j HEC95_RS16455 ENOG4108IEH NADH dehydrogenase subunit g HEC95_RS16460 ENOG4107QIZ NADH dehydrogenase HEC95_RS16465 ENOG4105GKE subunit e HEC95_RS16475 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HEC95_RS16480 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain HEC95_RS16490 ENOG4107NQ8 LysR family Transcriptional regulator HEC95_RS16495 ENOG4105CHM Aminotransferase HEC95_RS16505 ENOG4107QWE )-transporter HEC95_RS16510 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HEC95_RS16525 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HEC95_RS16530 ENOG4105C6K Malic enzyme HEC95_RS16535 ENOG4105CSX c4-dicarboxylate anaerobic carrier HEC95_RS16540 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) HEC95_RS16545 ENOG4108HHA Transketolase HEC95_RS16550 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HEC95_RS16560 ENOG4106ETB IIa component HEC95_RS16565 ENOG4105K2J Transcriptional regulator HEC95_RS16570 ENOG4105PTV Nudix Hydrolase HEC95_RS16575 ENOG4108RE9 Phosphodiesterase HEC95_RS16580 ENOG4108SHQ Glutathione S-transferase HEC95_RS16585 ENOG4105CYM Glutathione S-transferase HEC95_RS16590 ENOG4105ECP epimerase HEC95_RS16595 ENOG4108JEH abc transporter atp-binding protein HEC95_RS16600 ENOG4106YG3 ABC transporter HEC95_RS16605 ENOG4105DSP amino acid AbC transporter HEC95_RS16610 ENOG4105E89 ABC transporter HEC95_RS16615 ENOG4105E89 ABC transporter HEC95_RS16620 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HEC95_RS16625 ENOG4108IQI permease HEC95_RS16630 ENOG4106M28 alanine racemase domain protein HEC95_RS16635 ENOG4105E5D amino acid HEC95_RS16645 ENOG4108JUB Transcriptional regulator HEC95_RS16650 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HEC95_RS16655 ENOG4105E96 Colicin v production protein HEC95_RS16660 ENOG4108S3P Sporulation domain protein HEC95_RS16665 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HEC95_RS16675 ENOG4105DQR SNARE associated Golgi HEC95_RS16685 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HEC95_RS16695 ENOG4106WZ1 flagella biosynthesis regulator HEC95_RS16710 ENOG4105R8V Transcriptional regulator HEC95_RS16730 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HEC95_RS16740 ENOG4105MH2 YfcL protein HEC95_RS16745 ENOG4108BPE -transporting atpase HEC95_RS16750 ENOG4105EJ9 Membrane HEC95_RS16765 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) HEC95_RS16775 ENOG4108BY2 phosphohistidine phosphatase HEC95_RS16790 ENOG4105KZW UPF0381 protein HEC95_RS16795 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HEC95_RS16800 ENOG410903C (LipO)protein HEC95_RS16805 ENOG4105S64 Formate nitrite transporter HEC95_RS16820 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) HEC95_RS16825 ENOG4105CKK Glycosyl transferase, family 2 HEC95_RS16850 ENOG4108NC2 Outer membrane protease HEC95_RS16855 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta HEC95_RS16865 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC HEC95_RS16870 ENOG4105CXY transporter HEC95_RS16875 ENOG4105W9M Membrane HEC95_RS16880 ENOG4105D1S lipid A biosynthesis HEC95_RS16890 ENOG4105CHM Aminotransferase HEC95_RS16905 ENOG4107RA9 decarboxylase HEC95_RS16910 ENOG4105CPC Aldo Keto reductase HEC95_RS16915 ENOG4109076 Conserved Protein HEC95_RS16925 ENOG4105D9N nucleoside HEC95_RS16930 ENOG4108KMM Diguanylate cyclase HEC95_RS16945 ENOG4105HZG regulatoR HEC95_RS16950 ENOG4105GXM Putative transcription regulator (DUF1323) HEC95_RS16980 ENOG4105CN8 Transcriptional regulator HEC95_RS16990 ENOG4105EAA nucleoside HEC95_RS16995 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HEC95_RS17000 ENOG4108NFH Sugar hydrolase HEC95_RS17005 ENOG4108M0I Transcriptional regulator HEC95_RS17010 ENOG4105DHU Bile acid HEC95_RS17015 ENOG4105VRT cytoplasmic protein HEC95_RS17035 ENOG4105C6T cysteine synthase HEC95_RS17045 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HEC95_RS17050 ENOG4105C5Y PTS System HEC95_RS17060 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HEC95_RS17065 ENOG4105CSW GntR family transcriptional regulator HEC95_RS17070 ENOG41089BK Glutamine amido-transferase HEC95_RS17075 ENOG4105M0Y HEC95_RS17085 ENOG4105C6T cysteine synthase HEC95_RS17090 ENOG4108IJ6 ABC transporter HEC95_RS17095 ENOG4105ECW sulfate abc transporter HEC95_RS17100 ENOG4108I5D sulfate abc transporter HEC95_RS17105 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HEC95_RS17110 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HEC95_RS17115 ENOG4105EZR dyp-type peroxidase family protein HEC95_RS17120 ENOG4105E7K (LipO)protein HEC95_RS17125 ENOG4105QZU Inner membrane protein YfeZ HEC95_RS17130 ENOG4108R6G acetyltransferase HEC95_RS17135 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HEC95_RS17155 ENOG4108K3Z AraC family transcriptional regulator HEC95_RS17160 ENOG4108X49 Ethanolamine utilization protein EutK HEC95_RS17165 ENOG4106D67 ethanolamine utilization protein HEC95_RS17175 ENOG4105CPD ethanolamine ammonia-lyase HEC95_RS17180 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HEC95_RS17185 ENOG4105ENY Ethanolamine utilization protein eutH HEC95_RS17190 ENOG4105C0A alcohol dehydrogenase HEC95_RS17195 ENOG4107YMV ethanolamine utilization protein HEC95_RS17200 ENOG4108EKI Dehydrogenase HEC95_RS17205 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HEC95_RS17210 ENOG4105KNY Microcompartments protein HEC95_RS17215 ENOG4108IJ2 phosphate acetyltransferase HEC95_RS17220 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HEC95_RS17225 ENOG4105NDK ethanolamine utilization protein HEC95_RS17230 ENOG4106S4J ethanolamine utilization protein EutP HEC95_RS17235 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HEC95_RS17240 ENOG4105C6K Malic enzyme HEC95_RS17245 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HEC95_RS17250 ENOG4105CV1 Transketolase (EC 2.2.1.1) HEC95_RS17260 ENOG4108PVD exported protein HEC95_RS17265 ENOG4107VIJ nudix hydrolase HEC95_RS17275 ENOG4105BZ8 glutamate synthase HEC95_RS17280 ENOG4105BZU Histidine kinase HEC95_RS17285 ENOG4105BZS acriflavin resistance protein HEC95_RS17295 ENOG4105KUZ arsenate reductase HEC95_RS17300 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) HEC95_RS17310 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) HEC95_RS17315 ENOG4105CGZ zinc metallopeptidase HEC95_RS17325 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HEC95_RS17330 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HEC95_RS17335 ENOG4105RH4 Glycine cleavage system transcriptional repressor HEC95_RS17340 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HEC95_RS17345 ENOG4105BZW Glycerate kinase HEC95_RS17350 ENOG4107QQ0 gntp family HEC95_RS17355 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HEC95_RS17360 ENOG4105C02 permease HEC95_RS17365 ENOG4105ERG peptidase m48, ste24p HEC95_RS17370 ENOG4105K89 arsenate reductase HEC95_RS17380 ENOG4105C2W permease HEC95_RS17385 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) HEC95_RS17395 ENOG4108V3E phosphoribosylglycinamide formyltransferase HEC95_RS17400 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HEC95_RS17405 ENOG4105C9X ppx gppa phosphatase HEC95_RS17410 ENOG4105BZU Histidine kinase HEC95_RS17420 ENOG41062G3 Protein of unknown function (DUF2633) HEC95_RS17445 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HEC95_RS17485 ENOG4105VPD cellular component movement HEC95_RS17495 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HEC95_RS17500 ENOG4105N21 Membrane HEC95_RS17540 ENOG4105QAX Iron-sulfur HEC95_RS17545 ENOG4107QY8 reductase HEC95_RS17550 ENOG4108JQB penicillin-binding protein 1C HEC95_RS17555 ENOG4105DN3 alpha-2-macroglobulin domain protein HEC95_RS17560 ENOG4105KHC sulfurtransferase HEC95_RS17575 ENOG4105YYA enhanced serine sensitivity protein SseB HEC95_RS17585 ENOG4105WVQ Fe-S assembly protein IscX HEC95_RS17590 ENOG4108ZIT Ferredoxin, 2FE-2S HEC95_RS17605 ENOG4108Z4V iron-sulfur cluster assembly HEC95_RS17610 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HEC95_RS17625 ENOG4105CVS RNA methyltransferase TrmH family, group 1 HEC95_RS17630 ENOG4105ECY inositol monophosphatase HEC95_RS17635 ENOG4107XM9 (LipO)protein HEC95_RS17640 ENOG4105D5B Sulfite reductase, subunit A HEC95_RS17645 ENOG4107SHJ sulfite reductase subunit b HEC95_RS17650 ENOG410810Y Sulfite reductase HEC95_RS17655 ENOG4105D7X high-affinity nickel-transporter HEC95_RS17665 ENOG4108MN2 Stationary phase inducible protein CsiE HEC95_RS17670 ENOG4105D8G Major Facilitator superfamily HEC95_RS17680 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HEC95_RS17685 ENOG4108M3R transcriptional activator CadC HEC95_RS17690 ENOG4105D5Q Arginine ornithine antiporter HEC95_RS17695 ENOG4105CXN decarboxylase HEC95_RS17700 ENOG4105DUX Transporter HEC95_RS17710 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HEC95_RS17715 ENOG4108SKK alpha helix protein HEC95_RS17720 ENOG4107WP9 Histidine kinase HEC95_RS17725 ENOG4108ETH Formylglycinamide ribotide synthetase HEC95_RS17735 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) HEC95_RS17740 ENOG4108Z6B deaminase HEC95_RS17745 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HEC95_RS17760 ENOG4106G6Q Transcriptional regulator HEC95_RS17765 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HEC95_RS17775 ENOG4105DND Transcriptional regulator HEC95_RS17780 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HEC95_RS17790 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HEC95_RS17810 ENOG4105C3F Signal peptidase i HEC95_RS17820 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HEC95_RS17845 ENOG4108IYU L-aspartate oxidase HEC95_RS17855 ENOG4105C1J atp-dependent rna helicase HEC95_RS17860 ENOG41090KR LysR family transcriptional Regulator HEC95_RS17870 ENOG4108VKA Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity) HEC95_RS17880 ENOG4105EIB trna rrna methyltransferase HEC95_RS17885 ENOG4105K63 Thioredoxin HEC95_RS17890 ENOG4106IUH DTW domain containing protein HEC95_RS17895 ENOG4105CD5 CoA-binding domain protein HEC95_RS17900 ENOG4105JIM Phosphatidylserine synthase HEC95_RS17905 ENOG4105T42 (LipO)protein HEC95_RS17910 ENOG4105CSH Transporter HEC95_RS17940 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HEC95_RS17945 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HEC95_RS17950 ENOG4105C34 Pseudouridine synthase HEC95_RS17955 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HEC95_RS17960 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HEC95_RS17970 ENOG4105CQC Prephenate dehydratase HEC95_RS17980 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HEC95_RS17985 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HEC95_RS17990 ENOG4108WS1 HEC95_RS17995 ENOG4108KHX Diguanylate cyclase HEC95_RS18000 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) HEC95_RS18020 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HEC95_RS18025 ENOG4106KVJ cytochrome C assembly protein HEC95_RS18030 ENOG4108JU6 CBS domain protein HEC95_RS18050 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HEC95_RS18055 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HEC95_RS18065 ENOG4108Z1B Cyclase dehydrase HEC95_RS18085 ENOG4105BZ1 (ABC) transporter HEC95_RS18140 ENOG4105NIV Esterase HEC95_RS18145 ENOG4107RNH Outer membrane receptor FepA HEC95_RS18155 ENOG4105VRE Pentapeptide repeat protein HEC95_RS18160 ENOG4108MJ5 VirK protein HEC95_RS18175 ENOG4105DHQ Histidine kinase HEC95_RS18205 ENOG4105D5U fad dependent oxidoreductase HEC95_RS18210 ENOG4105C26 Dehydrogenase HEC95_RS18215 ENOG4108JPW Aminotransferase HEC95_RS18220 ENOG4105C85 amino acid HEC95_RS18225 ENOG4108PVQ transcriptional regulator HEC95_RS18230 ENOG4109066 lysm domain bon superfamily protein HEC95_RS18235 ENOG4105VPI YqaE family transport protein HEC95_RS18245 ENOG4105KJF protein tyrosine phosphatase HEC95_RS18255 ENOG41080HT Transcriptional regulator, arsr family HEC95_RS18260 ENOG4108V62 Rhodanese domain protein HEC95_RS18270 ENOG4108X73 DNA- binding protein HEC95_RS18275 ENOG4108RNS Exports L-alanine (By similarity) HEC95_RS18280 ENOG4108WMJ Protein of unknown function (DUF2002) HEC95_RS18285 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HEC95_RS18295 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HEC95_RS18300 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HEC95_RS18310 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HEC95_RS18315 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HEC95_RS18320 ENOG4108IJ7 Glycine betaine HEC95_RS18325 ENOG4108HQS Glycine betaine HEC95_RS18330 ENOG4105GIJ Glycine betaine HEC95_RS18340 ENOG4105NTK Transcriptional repressor Mpra HEC95_RS18345 ENOG4105CW7 secretion protein, HlyD family HEC95_RS18350 ENOG4105C0R drug resistance transporter emrb qaca subfamily HEC95_RS18370 ENOG4105W39 Membrane HEC95_RS18375 ENOG4107VXZ Hydrolase HEC95_RS18400 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HEC95_RS18405 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) HEC95_RS18420 ENOG4107TH8 cina domain protein HEC95_RS18425 ENOG4105CVE Lytic murein transglycosylase HEC95_RS18430 ENOG410787A Pts system, glucitol sorbitol-specific HEC95_RS18435 ENOG4105DZY Pts system, glucitol sorbitol-specific HEC95_RS18440 ENOG4105VI0 Pts system, glucitol sorbitol-specific HEC95_RS18445 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HEC95_RS18450 ENOG4105J92 DNA-binding transcriptional activator GutM HEC95_RS18455 ENOG410804X Transcriptional regulator HEC95_RS18460 ENOG4105C2X Arabinose 5-phosphate isomerase HEC95_RS18480 ENOG4105C8H hydrogenase maturation protein Hypf HEC95_RS18485 ENOG4108RC0 Electron transport protein HEC95_RS18495 ENOG4108MG9 hydrogenase 3 maturation protease HEC95_RS18500 ENOG4105I6X formate hydrogenlyase maturation HEC95_RS18505 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HEC95_RS18510 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HEC95_RS18515 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HEC95_RS18520 ENOG4107TDF Formate hydrogenlyase subunit 4 HEC95_RS18525 ENOG4107R30 NADH dehydrogenase HEC95_RS18530 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HEC95_RS18535 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HEC95_RS18540 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HEC95_RS18545 ENOG4107RSS Hydrogenase accessory protein HypB HEC95_RS18550 ENOG41083WG hydrogenase assembly chaperone HEC95_RS18555 ENOG4105CQS hydrogenase expression formation protein HypD HEC95_RS18560 ENOG4105C45 hydrogenase expression formation protein (HypE) HEC95_RS18570 ENOG4105VXR cytoplasmic protein HEC95_RS18580 ENOG4105DIK (ABC) transporter HEC95_RS18585 ENOG4105CC5 ABC transporter HEC95_RS18590 ENOG4105CC5 ABC transporter HEC95_RS18625 ENOG4108RBT type iii secretion HEC95_RS18630 ENOG4106BTR HEC95_RS18635 ENOG4105Y7Q type iii secretion HEC95_RS18640 ENOG4108RC9 Type III secretion system protein HEC95_RS18650 ENOG4108YAB Invasion protein HEC95_RS18660 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear HEC95_RS18675 ENOG41079WB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HEC95_RS18685 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC HEC95_RS18695 ENOG4106H1J Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE HEC95_RS18705 ENOG4108M6W surface presentation of antigens protein SpaS HEC95_RS18710 ENOG4108TN6 type iii secretion HEC95_RS18715 ENOG4105U07 type iii secretion HEC95_RS18720 ENOG41075IY surface presentation of antigens protein SpaP HEC95_RS18730 ENOG41078G4 surface presentation of HEC95_RS18735 ENOG41077MC Secretory protein (Associated with virulence) HEC95_RS18740 ENOG4108JIR Flagellum-specific ATP synthase HEC95_RS18745 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone HEC95_RS18750 ENOG4108HR8 type iii secretion HEC95_RS18755 ENOG4108N8R Invasion protein HEC95_RS18765 ENOG41090HZ type iii secretion HEC95_RS18795 ENOG4105MEW serine threonine protein phosphatase HEC95_RS18830 ENOG4105C0R drug resistance transporter emrb qaca subfamily HEC95_RS18835 ENOG4105JQN Transcriptional regulator HEC95_RS18840 ENOG4105C6Z Gluconate HEC95_RS18845 ENOG4105EXW epimerase dehydratase HEC95_RS18850 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HEC95_RS18860 ENOG4105G63 Type III effector Hrp-dependent HEC95_RS18870 ENOG4105MVE transcriptional regulator HEC95_RS18880 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HEC95_RS18885 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HEC95_RS18890 ENOG4105KZM cytoplasmic protein HEC95_RS18900 ENOG4108K5P (LipO)protein HEC95_RS18935 ENOG4105N0Z inner membrane protein ygbE HEC95_RS18955 ENOG4108MXK alkaline phosphatase isozyme conversion HEC95_RS18960 ENOG4105PWE CRISPR-associated protein cas2 HEC95_RS18965 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HEC95_RS18975 ENOG4108VWQ crispr-associated protein HEC95_RS18980 ENOG41060M0 Crispr-associated protein, cse4 family HEC95_RS18990 ENOG4105CYR Crispr-associated protein, cse1 family HEC95_RS18995 ENOG4105DTT CRISPR-associated helicase, cas3 HEC95_RS19020 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HEC95_RS19025 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) HEC95_RS19030 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HEC95_RS19035 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) HEC95_RS19045 ENOG4105DXN mazG family HEC95_RS19055 ENOG4106PG1 outer membrane usher protein HEC95_RS19060 ENOG4108FZ9 Chaperone HEC95_RS19065 ENOG4105NEV Fimbrial HEC95_RS19085 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HEC95_RS19090 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) HEC95_RS19095 ENOG4105BZU Histidine kinase HEC95_RS19100 ENOG4105BZW Glycerate kinase HEC95_RS19105 ENOG4105EQX glucarate dehydratase HEC95_RS19110 ENOG4105EQX glucarate dehydratase HEC95_RS19115 ENOG4105DJB Major Facilitator Superfamily HEC95_RS19125 ENOG4105QDK Flavodoxin HEC95_RS19130 ENOG4105DR9 pseudouridine synthase HEC95_RS19135 ENOG4105WP7 tRNA pseudouridine synthase C HEC95_RS19155 ENOG4105EWT decarboxylase family HEC95_RS19160 ENOG4105C44 Serine transporter HEC95_RS19165 ENOG4105EJQ L-serine dehydratase HEC95_RS19175 ENOG4105C0A alcohol dehydrogenase HEC95_RS19180 ENOG4107W7X Aldolase HEC95_RS19185 ENOG4105EDR glucose galactose transporter HEC95_RS19195 ENOG4105CMG Carbohydrate kinase HEC95_RS19205 ENOG4107EDW L-fucose operon activator HEC95_RS19215 ENOG4105M08 Membrane HEC95_RS19220 ENOG4105ETT transcriptional Regulator, LysR family HEC95_RS19225 ENOG4105M5B (LipO)protein HEC95_RS19230 ENOG4105C9B Cysteine desulfurase HEC95_RS19235 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HEC95_RS19240 ENOG4105FR1 rard protein HEC95_RS19245 ENOG4105CUZ uba thif-type nad fad binding protein HEC95_RS19250 ENOG4105CA3 membrane-bound lytic murein transglycosylase HEC95_RS19265 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HEC95_RS19270 ENOG4108EKC n-acetylglutamate synthase HEC95_RS19275 ENOG4107QYX exodeoxyribonuclease v alpha HEC95_RS19280 ENOG4107QKA exodeoxyribonuclease V beta HEC95_RS19285 ENOG4107QXK peptidase HEC95_RS19290 ENOG4105DSY exodeoxyribonuclease V, gamma HEC95_RS19295 ENOG4105RVB Prepilin peptidase dependent protein c HEC95_RS19300 ENOG4105SEN Protein of unknown function (DUF2509) HEC95_RS19305 ENOG4105JCS prepilin peptidase dependent protein HEC95_RS19310 ENOG4105IPU prepilin peptidase dependent protein A HEC95_RS19325 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HEC95_RS19340 ENOG4105EE5 Membrane protein terC HEC95_RS19345 ENOG4105SUV lipoprotein YgdR HEC95_RS19350 ENOG4105CPC Aldo Keto reductase HEC95_RS19370 ENOG4105DDV Transcriptional regulator (LacI family HEC95_RS19380 ENOG4105RQF LysR family Transcriptional regulator HEC95_RS19390 ENOG4107QNK )-transporter HEC95_RS19395 ENOG4105CHR reductase HEC95_RS19405 ENOG4105CHU acetyl-coa acetyltransferase HEC95_RS19410 ENOG4105C5Q Transcriptional regulator HEC95_RS19420 ENOG4108MHD transport protein HEC95_RS19450 ENOG4106P2F Pfam:Pili_assembly_C HEC95_RS19470 ENOG4108T1M outer membrane protein x HEC95_RS19475 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A HEC95_RS19480 ENOG4105VGJ Virulence-associated protein HEC95_RS19500 ENOG4108K5P (LipO)protein HEC95_RS19520 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HEC95_RS19525 ENOG4105T95 Thiol disulfide interChange protein HEC95_RS19530 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HEC95_RS19535 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HEC95_RS19540 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HEC95_RS19555 ENOG4108UT2 hemolysin iii HEC95_RS19565 ENOG4105CS2 ec 3.2.1.21 HEC95_RS19590 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HEC95_RS19595 ENOG4105D0A hydroxylase HEC95_RS19600 ENOG4107RAQ aminopeptidase HEC95_RS19620 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HEC95_RS19625 ENOG4108JQ1 Dehydrogenase HEC95_RS19640 ENOG4105MPN Membrane HEC95_RS19650 ENOG4105D64 Mechanosensitive ion channel HEC95_RS19655 ENOG4105D2N Aldolase HEC95_RS19660 ENOG4105BZA Phosphoglycerate kinase HEC95_RS19685 ENOG4108JJB ABC transporter HEC95_RS19690 ENOG4108JJB ABC transporter HEC95_RS19695 ENOG4105CV1 Transketolase (EC 2.2.1.1) HEC95_RS19700 ENOG4108K0D peptidase, M48 HEC95_RS19715 ENOG4108R66 Conserved Protein HEC95_RS19720 ENOG4105DG4 malate L-lactate dehydrogenase HEC95_RS19725 ENOG4105CPQ Dehydrogenase HEC95_RS19730 ENOG4105DEI Mannitol dehydrogenase HEC95_RS19740 ENOG4107YCY Transcriptional regulator HEC95_RS19750 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HEC95_RS19775 ENOG4107QNK )-transporter HEC95_RS19785 ENOG4105RWS endonuclease I HEC95_RS19790 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HEC95_RS19795 ENOG4105D7Z glutathione synthase HEC95_RS19815 ENOG4105CZX twitching motility protein HEC95_RS19820 ENOG4105DFA alanine racemase domain protein HEC95_RS19825 ENOG4108VIA integral membrane protein HEC95_RS19840 ENOG4105CSA Coproporphyrinogen iii oxidase HEC95_RS19845 ENOG4106MH3 alpha helix chain HEC95_RS19850 ENOG4105HDK L-asparaginase HEC95_RS19855 ENOG4105K33 Periplasmic Protein HEC95_RS19860 ENOG41090ED Protein with unknown function (DUF469) HEC95_RS19870 ENOG4105CEN a g-specific adenine glycosylase HEC95_RS19875 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) HEC95_RS19890 ENOG4105CXN decarboxylase HEC95_RS19895 ENOG4108UQV Membrane HEC95_RS19905 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase HEC95_RS19910 ENOG4105CYC Transferase HEC95_RS19915 ENOG4105DJG MaoC domain protein dehydratase HEC95_RS19920 ENOG4105CI0 Citrate lyase HEC95_RS19930 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) HEC95_RS19940 ENOG4108UAJ Transcriptional regulator HEC95_RS19950 ENOG4105CUB amino acid HEC95_RS19960 ENOG4105CJP fad dependent oxidoreductase HEC95_RS19965 ENOG4105C26 Dehydrogenase HEC95_RS19990 ENOG4105DPW Major facilitator superfamily MFS_1 HEC95_RS20000 ENOG4105DEI Mannitol dehydrogenase HEC95_RS20015 ENOG4106032 Glutathionylspermidine synthase HEC95_RS20020 ENOG4105CYM Glutathione S-transferase HEC95_RS20025 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein HEC95_RS20030 ENOG4105S10 periplasmic binding protein HEC95_RS20035 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HEC95_RS20040 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HEC95_RS20045 ENOG4108WGS hydrogenase 2-specific chaperone HEC95_RS20050 ENOG4108USZ hydrogenase HEC95_RS20055 ENOG4105DPX Hydrogenase, large subunit HEC95_RS20060 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HEC95_RS20065 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HEC95_RS20070 ENOG4105E3S small subunit HEC95_RS20075 ENOG410900S Protein of unknown function (DUF2623) HEC95_RS20080 ENOG4105C8Q Methyl-accepting chemotaxis HEC95_RS20105 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HEC95_RS20110 ENOG4108ZZF transport protein (ExbD) HEC95_RS20115 ENOG4105CWK Biopolymer transport protein, ExbB HEC95_RS20120 ENOG4105C28 cystathionine HEC95_RS20125 ENOG4108K81 inner membrane protein YghB HEC95_RS20130 ENOG4105CF7 AraC family transcriptional regulator HEC95_RS20135 ENOG4108I6A alcohol dehydrogenase HEC95_RS20140 ENOG4105CV8 reductase HEC95_RS20145 ENOG4107QPK )-transporter HEC95_RS20160 ENOG4105CCT upf0313 protein HEC95_RS20165 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HEC95_RS20175 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HEC95_RS20180 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HEC95_RS20185 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HEC95_RS20190 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HEC95_RS20195 ENOG4105F4I Transcriptional regulator HEC95_RS20200 ENOG4105H4F exported protein HEC95_RS20205 ENOG4105XJC Two component transcriptional regulator (Winged helix family HEC95_RS20210 ENOG4105DHQ Histidine kinase HEC95_RS20215 ENOG4105NF4 modulator of drug activity HEC95_RS20220 ENOG4105VRH Antibiotic biosynthesis monooxygenase HEC95_RS20225 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HEC95_RS20230 ENOG4105IPS esterase HEC95_RS20235 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HEC95_RS20240 ENOG4108SX3 cytoplasmic protein HEC95_RS20245 ENOG41087AY ADP-Ribose pyrophosphatase HEC95_RS20260 ENOG4106032 Glutathionylspermidine synthase HEC95_RS20265 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HEC95_RS20280 ENOG4108MR7 Arylsulfotransferase HEC95_RS20290 ENOG4108PSN Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity) HEC95_RS20300 ENOG4105W0Z cytoplasmic protein HEC95_RS20310 ENOG4105PV3 Inner membrane protein yqiJ HEC95_RS20315 ENOG4107S78 Band 7 protein HEC95_RS20335 ENOG4105I7R Adenylate cyclase HEC95_RS20340 ENOG4106MWK domain protein HEC95_RS20355 ENOG4107ZVW dihydroneopterin aldolase HEC95_RS20385 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HEC95_RS20390 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HEC95_RS20395 ENOG4108VCA G U mismatch-specific DNA glycosylase HEC95_RS20405 ENOG4105Q26 Siderophore-interacting protein HEC95_RS20410 ENOG4105NTW Transcriptional regulator HEC95_RS20415 ENOG4105C8Q Methyl-accepting chemotaxis HEC95_RS20420 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HEC95_RS20430 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HEC95_RS20440 ENOG4108VKG metal-dependent hydrolase HEC95_RS20445 ENOG4108UB4 uncharacterized protein ygjQ HEC95_RS20450 ENOG4105EE0 oxidoreductase HEC95_RS20455 ENOG4105DU1 integral membrane protein, terc HEC95_RS20465 ENOG4106W5V Membrane HEC95_RS20475 ENOG4105WAY exported protein HEC95_RS20480 ENOG4105NE1 Conserved Protein HEC95_RS20485 ENOG41090KG Inner membrane protein YqjE HEC95_RS20490 ENOG4105YJD HEC95_RS20495 ENOG4108VBZ doxx family HEC95_RS20500 ENOG4105CHF Glutathione S-transferase HEC95_RS20505 ENOG4105KAF membrAne HEC95_RS20510 ENOG4105CWB LysR family transcriptional Regulator HEC95_RS20515 ENOG4108CNN domain protein HEC95_RS20520 ENOG4106D80 Uncharacterized protein YhaL HEC95_RS20530 ENOG4105C44 Serine transporter HEC95_RS20535 ENOG4105EJQ L-serine dehydratase HEC95_RS20540 ENOG4105C6N Formate acetyltransferase HEC95_RS20555 ENOG4105C7B Threonine dehydratase HEC95_RS20560 ENOG410811B TRANSCRIPTIONal HEC95_RS20570 ENOG4105BZW Glycerate kinase HEC95_RS20575 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HEC95_RS20585 ENOG4105CTX dehydratase HEC95_RS20600 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HEC95_RS20605 ENOG41090UW PTS System HEC95_RS20610 ENOG4105DT3 PTS system, galactitol-specific IIc component HEC95_RS20615 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HEC95_RS20625 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HEC95_RS20630 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) HEC95_RS20645 ENOG4105W4M Transport-associated protein HEC95_RS20650 ENOG4105K4T epimerase HEC95_RS20655 ENOG4107R7Y intracellular protease Pfpi family HEC95_RS20670 ENOG4108YYD acetyltransferase HEC95_RS20690 ENOG4105DEN Luciferase family HEC95_RS20695 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HEC95_RS20705 ENOG4105CIC tryptophan-specific transport protein HEC95_RS20710 ENOG4105C1J atp-dependent rna helicase HEC95_RS20750 ENOG4105CHV Transcription elongation factor NusA HEC95_RS20755 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) HEC95_RS20780 ENOG4105NTZ Preprotein translocase subunit SecG HEC95_RS20790 ENOG4105EEI dihydropteroate synthase HEC95_RS20795 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HEC95_RS20805 ENOG4105HBR Rna-binding protein HEC95_RS20810 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HEC95_RS20815 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HEC95_RS20825 ENOG4105QYV Membrane HEC95_RS20830 ENOG4105K46 50S ribosomal protein l27 HEC95_RS20840 ENOG4105EAH synthase HEC95_RS20845 ENOG4105HVQ Regulatory factor of maltose metabolism HEC95_RS20855 ENOG4105VFK BolA family HEC95_RS20860 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HEC95_RS20865 ENOG4105E3I toluene tolerance HEC95_RS20870 ENOG4107PE3 Mammalian cell entry related domain protein HEC95_RS20875 ENOG4105CY3 ABC transporter, permease HEC95_RS20880 ENOG4105DHJ ABC, transporter HEC95_RS20885 ENOG4105FEU K -dependent Na -Ca exchanger HEC95_RS20890 ENOG4105C2X Arabinose 5-phosphate isomerase HEC95_RS20895 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase HEC95_RS20900 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HEC95_RS20905 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HEC95_RS20910 ENOG4108IUZ ABC transporter HEC95_RS20915 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HEC95_RS20920 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HEC95_RS20925 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HEC95_RS20935 ENOG41080Z8 PHOSPHOCARRIER protein HEC95_RS20940 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HEC95_RS20950 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HEC95_RS20955 ENOG4105BZU Histidine kinase HEC95_RS20960 ENOG4105N5T Radical SAM Protein HEC95_RS20965 ENOG4105CBC glutamate synthase HEC95_RS20970 ENOG4105BZ8 glutamate synthase HEC95_RS20975 ENOG4105DFS Conserved Protein HEC95_RS20980 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HEC95_RS20985 ENOG4105DZC cytosine deaminase HEC95_RS20990 ENOG4108R66 Conserved Protein HEC95_RS21020 ENOG4105KB2 stringent starvation protein b HEC95_RS21025 ENOG4107MKT Stringent starvation protein a HEC95_RS21045 ENOG4105D6Z AFG1 family ATPase HEC95_RS21050 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HEC95_RS21055 ENOG4105C0H protease HEC95_RS21065 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase HEC95_RS21070 ENOG4105D9Q decarboxylase (Beta subunit) HEC95_RS21075 ENOG4107QSA Oxaloacetate decarboxylase HEC95_RS21085 ENOG4107GFK fumarate HEC95_RS21090 ENOG4106DSS Tartrate dehydratase subunit alpha HEC95_RS21095 ENOG4105C8P )-transporter HEC95_RS21120 ENOG4105RID UPF0379 protein yhcN HEC95_RS21125 ENOG4105RID UPF0379 protein yhcN HEC95_RS21130 ENOG4105UNR (Barnase) inhibitor HEC95_RS21145 ENOG4105ZQC membrane protein AaeX HEC95_RS21150 ENOG4105CR8 Transcriptional regulator HEC95_RS21155 ENOG4105D1U peptidase U62 modulator of DNA gyrase HEC95_RS21160 ENOG4105QD6 exported protein HEC95_RS21165 ENOG4105C03 ribonuclease HEC95_RS21170 ENOG4108Z03 MAF-like protein HEC95_RS21175 ENOG4105VQ7 Rod shape-determining protein MreD HEC95_RS21180 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HEC95_RS21190 ENOG41062P1 Diguanylate cyclase phosphodiesterase HEC95_RS21195 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HEC95_RS21210 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HEC95_RS21215 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HEC95_RS21220 ENOG4105RG0 Membrane HEC95_RS21225 ENOG4108IA2 Sodium pantothenate symporter HEC95_RS21235 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HEC95_RS21245 ENOG4105CEC DNA methylase N-4 N-6 HEC95_RS21250 ENOG41061ME transport protein HEC95_RS21255 ENOG4105BZU Histidine kinase HEC95_RS21260 ENOG4108XG4 DNA-binding transcriptional regulator HEC95_RS21265 ENOG4105C1P efflux transporter, rnd family, mfp subunit HEC95_RS21270 ENOG4105BZS acriflavin resistance protein HEC95_RS21275 ENOG4105XCM membrane LIPOPROTEIN HEC95_RS21315 ENOG4105C12 Phosphoribosylglycinamide synthetase HEC95_RS21320 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HEC95_RS21325 ENOG4105BZU Histidine kinase HEC95_RS21335 ENOG4108T8B Protein of unknown function (DUF1481) HEC95_RS21340 ENOG4105K70 DNA-binding protein HEC95_RS21345 ENOG4105R2J Conserved Protein HEC95_RS21380 ENOG4105D06 uba thif-type nad fad binding protein HEC95_RS21385 ENOG4105WHD thiamine biosynthesis protein ThiS HEC95_RS21395 ENOG4105D41 biosynthesis protein thiH HEC95_RS21420 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) HEC95_RS21425 ENOG4107QIH DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) HEC95_RS21430 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) HEC95_RS21435 ENOG4108VZM 50s ribosomal protein L10 HEC95_RS21450 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HEC95_RS21455 ENOG4105PM1 preprotein translocase subunit SecE HEC95_RS21460 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) HEC95_RS21495 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HEC95_RS21545 ENOG4108Y73 Membrane HEC95_RS21560 ENOG4105C5Q Transcriptional regulator HEC95_RS21590 ENOG4105DIJ Phosphoethanolamine transferase HEC95_RS21595 ENOG4106R3P AraC family transcriptional regulator HEC95_RS21600 ENOG4108XCZ PTS System HEC95_RS21605 ENOG4108AHH pyruvate formate lyase II activase HEC95_RS21615 ENOG4108YRF PTS System HEC95_RS21620 ENOG4105DM4 PTS System HEC95_RS21625 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HEC95_RS21635 ENOG4105DCT glycerol dehydrogenase HEC95_RS21640 ENOG4108XC3 NADH ubiquinone oxidoreductase HEC95_RS21650 ENOG4105SYT Methylenetetrahydrofolate reductase HEC95_RS21660 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HEC95_RS21665 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) HEC95_RS21670 ENOG4105CGH 5'-nucleotidase HEC95_RS21685 ENOG4105D64 Mechanosensitive ion channel HEC95_RS21690 ENOG4105CFH Aspartokinase HEC95_RS21695 ENOG4105C28 cystathionine HEC95_RS21705 ENOG4108MR7 Arylsulfotransferase HEC95_RS21720 ENOG4105C25 Primosomal protein n' HEC95_RS21725 ENOG4105ETE Transcriptional regulator (LacI family HEC95_RS21730 ENOG41063M6 Cell Division Protein HEC95_RS21745 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HEC95_RS21760 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HEC95_RS21770 ENOG4105CBT Fructose-1,6-bisphosphatase HEC95_RS21775 ENOG4105DP0 ferredoxin-NADP reductase HEC95_RS21780 ENOG4108VTS Membrane HEC95_RS21785 ENOG4105EBK exported protein HEC95_RS21810 ENOG4105D4B ABC, transporter HEC95_RS21835 ENOG4107RYS Autoinducer-2 (AI-2) kinase HEC95_RS21845 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) HEC95_RS21865 ENOG4105D7K pfkb domain protein HEC95_RS21870 ENOG4105CT4 transporter HEC95_RS21880 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HEC95_RS21885 ENOG4105CTQ phosphohexokinase HEC95_RS21895 ENOG4105FMW periplasmic HEC95_RS21900 ENOG4105E3W Two component transcriptional regulator (Winged helix family HEC95_RS21905 ENOG4105E0F Histidine kinase HEC95_RS21920 ENOG4108RPX mosc domain containing protein HEC95_RS21925 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HEC95_RS21930 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HEC95_RS21935 ENOG4108QGT oligogalacturonate-specific porin HEC95_RS21970 ENOG4105C0A alcohol dehydrogenase HEC95_RS21985 ENOG4108UMN azlc family HEC95_RS21995 ENOG4108V87 frv operon regulatory protein HEC95_RS22015 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HEC95_RS22020 ENOG4108MG3 formate dehydrogenase HEC95_RS22035 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system HEC95_RS22045 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) HEC95_RS22050 ENOG4108Z3N Transcriptional regulator HEC95_RS22055 ENOG4105SUU thioesterase domain HEC95_RS22070 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HEC95_RS22075 ENOG4105E98 transcriptional regulator DeoR family HEC95_RS22080 ENOG4108MGF sugar kinase HEC95_RS22085 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HEC95_RS22090 ENOG4105D2M Aldolase HEC95_RS22095 ENOG4107QKS N-acylglucosamine 2-epimerase HEC95_RS22100 ENOG4107WI4 Aldose-1-epimerase HEC95_RS22105 ENOG4105CJQ hydrolase, family 31 HEC95_RS22110 ENOG4105CT4 transporter HEC95_RS22120 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is HEC95_RS22150 ENOG4108K4B hydrolase HEC95_RS22155 ENOG4105CI3 gtp-binding protein typa HEC95_RS22160 ENOG4105C5F glutamine synthetase HEC95_RS22165 ENOG4105CUX Signal transduction histidine kinase HEC95_RS22170 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HEC95_RS22175 ENOG4106FIY HEC95_RS22180 ENOG4105D4P Coproporphyrinogen iii oxidase HEC95_RS22200 ENOG4105C2M dna polymerase I HEC95_RS22205 ENOG4106HNH Acyl-transferase HEC95_RS22210 ENOG4108Z33 Thiol disulfide Interchange Protein HEC95_RS22220 ENOG4105PC1 Conserved Protein HEC95_RS22225 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HEC95_RS22230 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HEC95_RS22260 ENOG4108RR8 protoporphyrinogen oxidase HEC95_RS22265 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HEC95_RS22270 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HEC95_RS22285 ENOG4105CHU acetyl-coa acetyltransferase HEC95_RS22290 ENOG4108MR7 Arylsulfotransferase HEC95_RS22295 ENOG4107QK7 reductase HEC95_RS22300 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HEC95_RS22305 ENOG4105MDZ Transcriptional activator rfaH HEC95_RS22310 ENOG4105F8V Hydrolase, tatD family HEC95_RS22315 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HEC95_RS22320 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HEC95_RS22325 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HEC95_RS22335 ENOG4105JC1 sterol-binding domain protein HEC95_RS22345 ENOG4105CGY Dna recombination protein HEC95_RS22350 ENOG4107SXA Phosphorylase HEC95_RS22355 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HEC95_RS22360 ENOG4105C4X radical SAM domain protein HEC95_RS22370 ENOG4105DZ2 Transcriptional regulator HEC95_RS22375 ENOG4105EMK carboxylate amino acid amine transporter HEC95_RS22380 ENOG4105DQF Hydrolase HEC95_RS22385 ENOG4108EUD Lysophospholipase HEC95_RS22390 ENOG410829K Lysine exporter protein (Lyse ygga) HEC95_RS22395 ENOG4105CCF Lysine exporter protein (Lyse ygga) HEC95_RS22400 ENOG4105C9U ATP-dependent DNA helicase RecQ HEC95_RS22405 ENOG4105HDD phospholipase HEC95_RS22410 ENOG4108VUY thioesterase Superfamily protein HEC95_RS22415 ENOG4105FR1 rard protein HEC95_RS22430 ENOG4107QUT magnesium and cobalt transport protein CorA HEC95_RS22435 ENOG4105C4R Atp-dependent dna helicase HEC95_RS22440 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HEC95_RS22445 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HEC95_RS22450 ENOG4105CT0 Protein of unknown function, DUF484 HEC95_RS22460 ENOG4105S7Z (LipO)protein HEC95_RS22485 ENOG4107T0K Adenylate cyclase HEC95_RS22495 ENOG41076E6 Uroporphyrinogen-III Synthase HEC95_RS22500 ENOG4105ECF c-methyltransferase HEC95_RS22505 ENOG410601J HemY protein HEC95_RS22530 ENOG4105C85 amino acid HEC95_RS22550 ENOG4105EGZ biosynthesis protein HEC95_RS22555 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HEC95_RS22560 ENOG4108WJ1 acetyltransferase HEC95_RS22565 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HEC95_RS22565 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HEC95_RS22570 ENOG4105C1B dTDP-glucose 4-6-dehydratase HEC95_RS22575 ENOG4108IJ1 Dehydrogenase HEC95_RS22580 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HEC95_RS22585 ENOG4105SFE lipopolysaccharide biosynthesis protein HEC95_RS22590 ENOG4105ESV Glycosyl transferase, family 4 HEC95_RS22595 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HEC95_RS22620 ENOG4105C4R Atp-dependent dna helicase HEC95_RS22630 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HEC95_RS22640 ENOG4105EMY transcriptional regulator HEC95_RS22655 ENOG4105C7B Threonine dehydratase HEC95_RS22665 ENOG4105CM2 brancheD-chain amino acid aminotransferase HEC95_RS22670 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HEC95_RS22685 ENOG4105C0P Mg chelatase subunit ChlI HEC95_RS22730 ENOG4107EJG GntR family transcriptional regulator HEC95_RS22735 ENOG4105C0R drug resistance transporter emrb qaca subfamily HEC95_RS22740 ENOG4105C0R drug resistance transporter emrb qaca subfamily HEC95_RS22745 ENOG4105ETE Transcriptional regulator (LacI family HEC95_RS22750 ENOG4108RVA ribokinase HEC95_RS22755 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HEC95_RS22760 ENOG4105CNN ABC, transporter HEC95_RS22765 ENOG4105C2J ABC transporter HEC95_RS22795 ENOG4108VVK transcriptional Regulator, AsnC HEC95_RS22800 ENOG4105QTB Flavodoxin HEC95_RS22815 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HEC95_RS22830 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) HEC95_RS22850 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) HEC95_RS22855 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) HEC95_RS22870 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HEC95_RS22875 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) HEC95_RS22880 ENOG4105F9E Shikimate 5-dehydrogenase HEC95_RS22885 ENOG4105DM4 PTS System HEC95_RS22890 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HEC95_RS22895 ENOG4105C8U phosphate abc transporter HEC95_RS22900 ENOG4105E2Z phosphate ABC transporter (Permease HEC95_RS22905 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HEC95_RS22915 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HEC95_RS22920 ENOG4105C7N Xanthine uracil vitamin C permease HEC95_RS22925 ENOG4108YYH Nadph-dependent fmn reductase HEC95_RS22930 ENOG4105E8Q phosphopantetheinyl transferase HEC95_RS22965 ENOG4105VG0 50S ribosomal protein l34 HEC95_RS22975 ENOG41064SU resolvase HEC95_RS22980 ENOG4105H4F exported protein HEC95_RS23030 ENOG4108Z33 Thiol disulfide Interchange Protein HEC95_RS23040 ENOG4108ZK4 sdia-regulated domain-containing protein HEC95_RS23045 ENOG4105H38 Membrane HEC95_RS23050 ENOG4108NKV transcriptional regulator HEC95_RS23055 ENOG4108ZK4 sdia-regulated domain-containing protein HEC95_RS23060 ENOG4106CQM replication HEC95_RS23070 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) HEC95_RS23300 ENOG4105TNG K13735 adhesin invasin