locus-tag	class	description
HEC95_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
HEC95_RS00035	COG2271	Major facilitator Superfamily
HEC95_RS00040	COG0561	phosphatase activity
HEC95_RS00045	COG2186	Transcriptional regulator
HEC95_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
HEC95_RS00055	COG0800	Aldolase
HEC95_RS00065	COG2271	Major facilitator Superfamily
HEC95_RS00070	COG2205	protein histidine kinase activity
HEC95_RS00070	COG2198	Histidine kinase
HEC95_RS00070	COG0784	Response regulator, receiver
HEC95_RS00075	COG1879	ABC-type sugar transport system periplasmic component
HEC95_RS00080	COG0745	RESPONSE REGULATOR receiver
HEC95_RS00085	COG3005	denitrification pathway
HEC95_RS00100	COG1858	cytochrome C peroxidase
HEC95_RS00105	COG4133	protoheme IX ABC transporter activity
HEC95_RS00110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HEC95_RS00115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HEC95_RS00120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HEC95_RS00130	COG1138	Cytochrome C-type biogenesis protein
HEC95_RS00140	COG3088	subunit of a heme lyase
HEC95_RS00140	COG4235	cytochrome complex assembly
HEC95_RS00145	COG0823	Involved in the tonB-independent uptake of proteins
HEC95_RS00150	COG5645	(Lipo)protein
HEC95_RS00170	COG2149	membrane
HEC95_RS00180	COG0641	radical SAM
HEC95_RS00190	COG2610	gluconate transmembrane transporter activity
HEC95_RS00195	COG0583	DNA-binding transcription factor activity
HEC95_RS00205	COG2814	Major facilitator Superfamily
HEC95_RS00230	COG0028	Belongs to the TPP enzyme family
HEC95_RS00235	COG0440	acetolactate synthase activity
HEC95_RS00240	COG1349	DNA-binding transcription factor activity
HEC95_RS00250	COG0738	Major facilitator superfamily
HEC95_RS00300	COG2723	6-phospho-beta-galactosidase activity
HEC95_RS00320	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEC95_RS00320	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS00325	COG3715	PTS system
HEC95_RS00330	COG3716	PTS system mannose fructose sorbose family IID component
HEC95_RS00345	COG5464	transposase or invertase
HEC95_RS00375	COG1335	isochorismatase
HEC95_RS00385	COG3710	Transcriptional regulator
HEC95_RS00400	COG2771	luxR family
HEC95_RS00445	COG2211	Major facilitator Superfamily
HEC95_RS00450	COG1501	Belongs to the glycosyl hydrolase 31 family
HEC95_RS00455	COG2982	Protein involved in outer membrane biogenesis
HEC95_RS00460	COG2233	PERMEase
HEC95_RS00465	COG0786	glutamate:sodium symporter activity
HEC95_RS00470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEC95_RS00475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEC95_RS00480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEC95_RS00500	COG2860	membrane
HEC95_RS00510	COG0583	DNA-binding transcription factor activity
HEC95_RS00515	COG1561	YicC-like family, N-terminal region
HEC95_RS00540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEC95_RS00570	COG1519	Transferase
HEC95_RS00575	COG0859	PFAM glycosyl transferase family 9
HEC95_RS00580	COG0438	transferase activity, transferring glycosyl groups
HEC95_RS00655	COG1216	Glycosyl transferase, family 2
HEC95_RS00660	COG2861	carbohydrate metabolic process
HEC95_RS00665	COG4942	peptidase
HEC95_RS00675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEC95_RS00680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HEC95_RS00700	COG2271	Major facilitator Superfamily
HEC95_RS00710	COG1609	Transcriptional regulator
HEC95_RS00715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HEC95_RS00725	COG2186	Transcriptional regulator
HEC95_RS00755	COG3722	fumarate hydratase activity
HEC95_RS00765	COG2213	PTS system mannitol-specific
HEC95_RS00765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS00770	COG0625	glutathione transferase activity
HEC95_RS00780	COG3276	selenocysteine insertion sequence binding
HEC95_RS00785	COG1940	carbohydrate kinase activity
HEC95_RS00790	COG1012	belongs to the aldehyde dehydrogenase family
HEC95_RS00805	COG0235	Class ii aldolase
HEC95_RS00810	COG3623	hexulose-6-phosphate isomerase
HEC95_RS00815	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HEC95_RS00820	COG1070	Carbohydrate kinase
HEC95_RS00825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HEC95_RS00830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HEC95_RS00835	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HEC95_RS00845	COG2731	YhcH YjgK YiaL family protein
HEC95_RS00855	COG1414	Transcriptional regulator
HEC95_RS00860	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HEC95_RS00865	COG3977	Valine--pyruvate aminotransferase
HEC95_RS00870	COG0366	Alpha amylase catalytic
HEC95_RS00875	COG2992	FlgJ-related protein
HEC95_RS00880	COG1609	Transcriptional regulator
HEC95_RS00880	COG2207	Transcriptional regulator
HEC95_RS00890	COG1070	Carbohydrate kinase
HEC95_RS00895	COG4682	membrane
HEC95_RS00900	COG3274	enterobacterial common antigen metabolic process
HEC95_RS00920	COG2801	Transposase and inactivated derivatives
HEC95_RS00945	COG1278	Cold shock
HEC95_RS00950	COG2944	sequence-specific DNA binding
HEC95_RS00965	COG2885	chlorophyll binding
HEC95_RS00970	COG0243	molybdopterin cofactor binding
HEC95_RS00975	COG0456	acetyltransferase
HEC95_RS00980	COG2818	Glycosylase
HEC95_RS00985	COG5571	outer membrane autotransporter
HEC95_RS01035	COG1609	Transcriptional regulator
HEC95_RS01050	COG0747	negative chemotaxis
HEC95_RS01055	COG0601	transmembrane transport
HEC95_RS01060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEC95_RS01065	COG0444	Belongs to the ABC transporter superfamily
HEC95_RS01070	COG4608	Belongs to the ABC transporter superfamily
HEC95_RS01075	COG0814	amino acid
HEC95_RS01125	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEC95_RS01135	COG2200	EAL domain
HEC95_RS01135	COG2199	diguanylate cyclase activity
HEC95_RS01150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS01155	COG2200	EAL domain
HEC95_RS01160	COG2982	Protein involved in outer membrane biogenesis
HEC95_RS01165	COG0477	Major facilitator Superfamily
HEC95_RS01170	COG1295	ribonuclease BN
HEC95_RS01175	COG0583	DNA-binding transcription factor activity
HEC95_RS01180	COG2197	response regulator
HEC95_RS01200	COG2188	Transcriptional regulator
HEC95_RS01205	COG2222	sugar isomerase
HEC95_RS01210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS01215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HEC95_RS01225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEC95_RS01230	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HEC95_RS01235	COG0671	phosphoesterase, PA-phosphatase related
HEC95_RS01265	COG0306	phosphate transporter
HEC95_RS01270	COG2081	HI0933 family
HEC95_RS01275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEC95_RS01280	COG0842	Transport permease protein
HEC95_RS01280	COG1129	ABC transporter
HEC95_RS01285	COG0842	Transport permease protein
HEC95_RS01295	COG2091	lysine biosynthetic process via aminoadipic acid
HEC95_RS01300	COG0628	permease
HEC95_RS01315	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEC95_RS01335	COG3714	YhhN family
HEC95_RS01345	COG3776	membrane
HEC95_RS01350	COG0742	ribosomal rna small subunit methyltransferase
HEC95_RS01355	COG0552	protein localization to endoplasmic reticulum
HEC95_RS01360	COG2884	Cell division ATP-binding protein ftsE
HEC95_RS01365	COG2177	Part of the ABC transporter FtsEX involved in
HEC95_RS01445	COG0584	glycerophosphoryl diester phosphodiesterase
HEC95_RS01455	COG0405	Gamma-glutamyltransferase
HEC95_RS01460	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HEC95_RS01475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS01480	COG1247	-acetyltransferase
HEC95_RS01485	COG0673	inositol 2-dehydrogenase activity
HEC95_RS01490	COG1741	Belongs to the pirin family
HEC95_RS01495	COG1609	Transcriptional regulator
HEC95_RS01500	COG3265	gluconokinase activity
HEC95_RS01505	COG2610	gluconate transmembrane transporter activity
HEC95_RS01520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEC95_RS01540	COG0058	SHG alpha-glucan phosphorylase activity
HEC95_RS01545	COG1414	Transcriptional regulator
HEC95_RS01550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEC95_RS01555	COG0129	dihydroxy-acid dehydratase activity
HEC95_RS01565	COG0371	Dehydrogenase
HEC95_RS01580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEC95_RS01595	COG1349	DNA-binding transcription factor activity
HEC95_RS01600	COG4650	regulator
HEC95_RS01610	COG1690	Belongs to the RtcB family
HEC95_RS01620	COG3077	Addiction module antitoxin, RelB DinJ family
HEC95_RS01625	COG3041	Addiction module toxin RelE StbE family
HEC95_RS01635	COG0058	SHG alpha-glucan phosphorylase activity
HEC95_RS01640	COG1640	4-alpha-glucanotransferase
HEC95_RS01645	COG2610	gluconate transmembrane transporter activity
HEC95_RS01665	COG5464	transposase or invertase
HEC95_RS01680	COG1918	ferrous iron import across plasma membrane
HEC95_RS01685	COG2183	response to ionizing radiation
HEC95_RS01690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HEC95_RS01695	COG0745	RESPONSE REGULATOR receiver
HEC95_RS01710	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HEC95_RS01720	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HEC95_RS01725	COG1011	Hydrolase
HEC95_RS01735	COG0494	nUDIX hydrolase
HEC95_RS01740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HEC95_RS01745	COG4972	Pilus assembly protein
HEC95_RS01750	COG3166	PFAM Fimbrial assembly family protein
HEC95_RS01765	COG4796	Type ii and iii secretion system protein
HEC95_RS01780	COG3266	domain, Protein
HEC95_RS01785	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HEC95_RS01790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HEC95_RS01830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEC95_RS01865	COG1289	transmembrane transporter activity
HEC95_RS01875	COG1765	OsmC-like protein
HEC95_RS01880	COG3954	Phosphoribulokinase
HEC95_RS01890	COG0429	hydrolase of the alpha beta-hydrolase fold
HEC95_RS01905	COG0488	(ABC) transporter
HEC95_RS01920	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HEC95_RS01925	COG1047	Peptidyl-prolyl cis-trans
HEC95_RS01935	COG0545	Peptidyl-prolyl cis-trans isomerase
HEC95_RS01940	COG2964	Protein conserved in bacteria
HEC95_RS01995	COG0051	transcription antitermination factor activity, RNA binding
HEC95_RS02020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEC95_RS02100	COG0201	protein transport
HEC95_RS02140	COG0789	Transcriptional regulator
HEC95_RS02145	COG3036	rescue of stalled ribosome
HEC95_RS02175	COG0758	DNA mediated transformation
HEC95_RS02185	COG0551	DNA topoisomerase type I activity
HEC95_RS02205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEC95_RS02245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HEC95_RS02290	COG3122	Protein conserved in bacteria
HEC95_RS02305	COG1349	DNA-binding transcription factor activity
HEC95_RS02310	COG0561	phosphatase activity
HEC95_RS02340	COG0527	aspartate kinase activity
HEC95_RS02365	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HEC95_RS02420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HEC95_RS02430	COG0534	Mate efflux family protein
HEC95_RS02445	COG0735	belongs to the Fur family
HEC95_RS02495	COG2315	Protein conserved in bacteria
HEC95_RS02555	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HEC95_RS02575	COG2252	PERMEase
HEC95_RS02580	COG0025	NhaP-type Na H and K H
HEC95_RS02585	COG0583	DNA-binding transcription factor activity
HEC95_RS02590	COG1380	Effector of murein hydrolase LrgA
HEC95_RS02595	COG1346	cytolysis
HEC95_RS02605	COG3162	membrane
HEC95_RS02610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HEC95_RS02620	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HEC95_RS02625	COG0437	4 iron, 4 sulfur cluster binding
HEC95_RS02630	COG3301	Polysulphide reductase, NrfD
HEC95_RS02635	COG1138	Cytochrome C-type biogenesis protein
HEC95_RS02640	COG3088	subunit of a heme lyase
HEC95_RS02645	COG4235	cytochrome complex assembly
HEC95_RS02650	COG1301	dicarboxylic acid transport
HEC95_RS02655	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HEC95_RS02675	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HEC95_RS02680	COG2824	Alkylphosphonate utilization operon protein PhnA
HEC95_RS02710	COG0531	amino acid
HEC95_RS02715	COG2207	Transcriptional regulator
HEC95_RS02720	COG1982	Orn Lys Arg decarboxylase major
HEC95_RS02725	COG2169	Transcriptional regulator
HEC95_RS02740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HEC95_RS02740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HEC95_RS02745	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HEC95_RS02755	COG4565	transcriptional regulatory protein
HEC95_RS02760	COG3290	protein histidine kinase activity
HEC95_RS02770	COG0437	4 iron, 4 sulfur cluster binding
HEC95_RS02775	COG3302	dmso reductase anchor subunit
HEC95_RS02780	COG3381	protein complex oligomerization
HEC95_RS02800	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HEC95_RS02805	COG2197	response regulator
HEC95_RS02845	COG1309	transcriptional regulator
HEC95_RS02860	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HEC95_RS02865	COG1027	Aspartate ammonia-lyase
HEC95_RS02870	COG3030	protein affecting phage T7 exclusion by the F plasmid
HEC95_RS02875	COG0531	amino acid
HEC95_RS02915	COG5510	response to toxic substance
HEC95_RS02945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HEC95_RS02950	COG1053	succinate dehydrogenase
HEC95_RS02970	COG3264	Mechanosensitive ion channel
HEC95_RS02970	COG1511	domain protein
HEC95_RS02990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEC95_RS03015	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEC95_RS03015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HEC95_RS03020	COG0802	atpase or kinase
HEC95_RS03045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEC95_RS03050	COG0330	HflC and HflK could
HEC95_RS03055	COG0330	HflC and HflK could
HEC95_RS03060	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HEC95_RS03075	COG0557	exoribonuclease II activity
HEC95_RS03085	COG3789	protein conserved in bacteria
HEC95_RS03090	COG1842	Phage shock protein A
HEC95_RS03105	COG3766	membrane
HEC95_RS03110	COG5463	Belongs to the UPF0441 family
HEC95_RS03115	COG0754	glutathionylspermidine amidase activity
HEC95_RS03120	COG1960	acyl-CoA dehydrogenase activity
HEC95_RS03130	COG3650	response to hydrogen peroxide
HEC95_RS03135	COG1073	alpha beta
HEC95_RS03155	COG3414	Phosphotransferase system galactitol-specific IIB component
HEC95_RS03195	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEC95_RS03210	COG3061	Opacity-associated protein A
HEC95_RS03215	COG0545	Peptidyl-prolyl cis-trans isomerase
HEC95_RS03220	COG1113	amino acid transport
HEC95_RS03240	COG0697	spore germination
HEC95_RS03245	COG0702	epimerase
HEC95_RS03250	COG1733	regulation of RNA biosynthetic process
HEC95_RS03265	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HEC95_RS03275	COG1253	flavin adenine dinucleotide binding
HEC95_RS03295	COG2105	PFAM AIG2 family protein
HEC95_RS03300	COG2271	Major facilitator Superfamily
HEC95_RS03305	COG3964	amidohydrolase
HEC95_RS03320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HEC95_RS03330	COG0312	modulator of DNA gyrase
HEC95_RS03365	COG3964	amidohydrolase
HEC95_RS03380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS03380	COG3711	transcriptional antiterminator
HEC95_RS03385	COG3077	Addiction module antitoxin, RelB DinJ family
HEC95_RS03390	COG2026	Addiction module toxin, RelE StbE family
HEC95_RS03405	COG0366	Alpha amylase catalytic
HEC95_RS03410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEC95_RS03410	COG1263	PTS System
HEC95_RS03460	COG1438	arginine binding
HEC95_RS03465	COG1288	antiporter activity
HEC95_RS03485	COG2731	YhcH YjgK YiaL family protein
HEC95_RS03525	COG2927	DNA polymerase III (CHI subunit)
HEC95_RS03535	COG0795	lipopolysaccharide-transporting ATPase activity
HEC95_RS03540	COG0795	lipopolysaccharide-transporting ATPase activity
HEC95_RS03545	COG1609	Transcriptional regulator
HEC95_RS03550	COG2610	gluconate transmembrane transporter activity
HEC95_RS03555	COG1028	Short-chain dehydrogenase reductase Sdr
HEC95_RS03560	COG1063	alcohol dehydrogenase
HEC95_RS03565	COG3265	gluconokinase activity
HEC95_RS03570	COG1064	alcohol dehydrogenase
HEC95_RS03655	COG3204	pilus organization
HEC95_RS03675	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HEC95_RS03700	COG0412	Dienelactone hydrolase
HEC95_RS03705	COG2186	Transcriptional regulator
HEC95_RS03725	COG0583	DNA-binding transcription factor activity
HEC95_RS03730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEC95_RS03735	COG0700	Nucleoside recognition
HEC95_RS03740	COG3366	ferrous iron transmembrane transporter activity
HEC95_RS03745	COG0477	Major facilitator Superfamily
HEC95_RS03750	COG2733	membrane
HEC95_RS03760	COG5464	transposase or invertase
HEC95_RS03765	COG1012	belongs to the aldehyde dehydrogenase family
HEC95_RS03780	COG3586	endonuclease activity
HEC95_RS03785	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HEC95_RS03790	COG0732	type I restriction modification DNA specificity domain
HEC95_RS03795	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HEC95_RS03815	COG0523	cobalamin synthesis protein
HEC95_RS03820	COG2879	small protein
HEC95_RS03825	COG1966	Carbon starvation protein
HEC95_RS03830	COG0840	transmembrane signaling receptor activity
HEC95_RS03845	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEC95_RS03850	COG3715	PTS system
HEC95_RS03855	COG3716	PTS system mannose fructose sorbose family IID component
HEC95_RS03860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HEC95_RS03880	COG1484	DNA-dependent DNA replication
HEC95_RS03895	COG2966	Psort location CytoplasmicMembrane, score
HEC95_RS03900	COG2197	response regulator
HEC95_RS03905	COG2197	response regulator
HEC95_RS03910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEC95_RS03915	COG4114	ferric iron reductase
HEC95_RS03920	COG3706	GGDEF domain
HEC95_RS03950	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HEC95_RS03960	COG1011	Hydrolase
HEC95_RS03970	COG2823	Periplasmic or secreted lipoprotein
HEC95_RS03980	COG4667	esterase of the alpha-beta hydrolase superfamily
HEC95_RS03985	COG0084	hydrolase, TatD family'
HEC95_RS03990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEC95_RS03995	COG1328	CTP reductase activity
HEC95_RS04020	COG3550	peptidyl-serine autophosphorylation
HEC95_RS04030	COG3726	membrane protein affecting hemolysin expression
HEC95_RS04035	COG0560	Phosphoserine phosphatase
HEC95_RS04050	COG0488	(ABC) transporter
HEC95_RS04075	COG2207	Transcriptional regulator
HEC95_RS04075	COG3708	Transcriptional regulator
HEC95_RS04080	COG3045	CreA protein
HEC95_RS04085	COG0745	RESPONSE REGULATOR receiver
HEC95_RS04090	COG2205	protein histidine kinase activity
HEC95_RS04095	COG4452	Inner membrane protein CreD
HEC95_RS04115	COG3121	Chaperone
HEC95_RS04135	COG0745	RESPONSE REGULATOR receiver
HEC95_RS04145	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HEC95_RS04155	COG0460	homoserine dehydrogenase
HEC95_RS04155	COG0527	aspartate kinase activity
HEC95_RS04165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEC95_RS04175	COG1115	amino acid carrier protein
HEC95_RS04185	COG0521	Mo-molybdopterin cofactor biosynthetic process
HEC95_RS04190	COG1584	GPR1 FUN34 yaaH family protein
HEC95_RS04195	COG4735	regulation of single-species biofilm formation
HEC95_RS04260	COG3188	usher protein
HEC95_RS04275	COG3539	Fimbrial protein
HEC95_RS04280	COG3121	Chaperone
HEC95_RS04300	COG0583	DNA-binding transcription factor activity
HEC95_RS04315	COG0737	Belongs to the 5'-nucleotidase family
HEC95_RS04325	COG3119	arylsulfatase activity
HEC95_RS04330	COG0641	radical SAM
HEC95_RS04350	COG0583	DNA-binding transcription factor activity
HEC95_RS04375	COG0196	riboflavin kinase activity
HEC95_RS04390	COG1047	Peptidyl-prolyl cis-trans
HEC95_RS04540	COG0644	oxidoreductase
HEC95_RS04550	COG2271	Major facilitator Superfamily
HEC95_RS04570	COG3119	arylsulfatase activity
HEC95_RS04605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HEC95_RS04635	COG0417	DNA replication proofreading
HEC95_RS04675	COG0586	Pfam SNARE associated Golgi protein
HEC95_RS04770	COG0768	penicillin binding
HEC95_RS04780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HEC95_RS04795	COG0772	Belongs to the SEDS family
HEC95_RS04820	COG0849	cell division
HEC95_RS04825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEC95_RS04845	COG0494	nUDIX hydrolase
HEC95_RS04855	COG0583	DNA-binding transcription factor activity
HEC95_RS04880	COG1459	type II secretion system
HEC95_RS04885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEC95_RS04890	COG4969	Belongs to the N-Me-Phe pilin family
HEC95_RS04905	COG3725	Membrane protein required for beta-lactamase induction
HEC95_RS04910	COG3940	Belongs to the glycosyl hydrolase 43 family
HEC95_RS04915	COG2211	Major facilitator Superfamily
HEC95_RS04930	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HEC95_RS04935	COG0508	dehydrogenase complex catalyzes the overall conversion of
HEC95_RS04940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEC95_RS04955	COG3064	Membrane
HEC95_RS04995	COG1349	DNA-binding transcription factor activity
HEC95_RS05015	COG2132	Multicopper oxidase
HEC95_RS05020	COG4993	Dehydrogenase
HEC95_RS05030	COG0288	reversible hydration of carbon dioxide
HEC95_RS05035	COG1131	(ABC) transporter
HEC95_RS05040	COG0842	Transport permease protein
HEC95_RS05045	COG3539	Fimbrial protein
HEC95_RS05065	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS05070	COG0726	polysaccharide deacetylase
HEC95_RS05090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEC95_RS05115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEC95_RS05120	COG1643	Atp-dependent helicase
HEC95_RS05125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HEC95_RS05130	COG4774	siderophore transport
HEC95_RS05135	COG1120	ATPase activity
HEC95_RS05140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HEC95_RS05155	COG3188	usher protein
HEC95_RS05160	COG3121	Chaperone
HEC95_RS05165	COG3539	Fimbrial protein
HEC95_RS05170	COG3539	Fimbrial protein
HEC95_RS05200	COG2860	membrane
HEC95_RS05225	COG3835	regulator
HEC95_RS05240	COG0477	Major facilitator Superfamily
HEC95_RS05290	COG0575	Belongs to the CDS family
HEC95_RS05355	COG0346	lactoylglutathione lyase activity
HEC95_RS05365	COG4568	rho-dependent transcription termination
HEC95_RS05380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEC95_RS05385	COG3015	lipoprotein NlpE involved in copper resistance
HEC95_RS05395	COG1720	tRNA m6t6A37 methyltransferase activity
HEC95_RS05455	COG0656	L-ascorbic acid biosynthetic process
HEC95_RS05460	COG0583	DNA-binding transcription factor activity
HEC95_RS05465	COG2814	Major facilitator Superfamily
HEC95_RS05475	COG2226	methyltransferase
HEC95_RS05480	COG1388	LysM domain
HEC95_RS05480	COG0741	lytic transglycosylase activity
HEC95_RS05490	COG2226	methyltransferase
HEC95_RS05535	COG3209	COG3209 Rhs family protein
HEC95_RS05635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HEC95_RS05650	COG0121	glutamine amidotransferase
HEC95_RS05655	COG3034	peptidoglycan biosynthetic process
HEC95_RS05665	COG1690	Belongs to the RtcB family
HEC95_RS05670	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEC95_RS05675	COG2195	Cleaves the N-terminal amino acid of tripeptides
HEC95_RS05715	COG0582	viral genome integration into host DNA
HEC95_RS05740	COG2814	Major facilitator Superfamily
HEC95_RS05755	COG0179	Fumarylacetoacetate (FAA) hydrolase
HEC95_RS05790	COG3188	usher protein
HEC95_RS05795	COG3121	Chaperone
HEC95_RS05800	COG3539	Fimbrial protein
HEC95_RS05815	COG2200	EAL domain
HEC95_RS05860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEC95_RS05865	COG2217	Heavy metal translocating P-type atpase
HEC95_RS05870	COG0789	Transcriptional regulator
HEC95_RS05880	COG2814	Major facilitator Superfamily
HEC95_RS05900	COG1271	oxidase subunit
HEC95_RS05905	COG1294	oxidase, subunit
HEC95_RS05925	COG1280	lysine exporter protein (LysE YggA)
HEC95_RS05950	COG2079	MmgE PrpD family protein
HEC95_RS05960	COG0113	porphobilinogen synthase activity
HEC95_RS05975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HEC95_RS05980	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HEC95_RS06025	COG3706	GGDEF domain
HEC95_RS06030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEC95_RS06050	COG4126	flavin adenine dinucleotide binding
HEC95_RS06065	COG1940	carbohydrate kinase activity
HEC95_RS06070	COG2814	Major facilitator Superfamily
HEC95_RS06075	COG0419	ATPase involved in DNA repair
HEC95_RS06080	COG0420	3'-5' exonuclease activity
HEC95_RS06090	COG5002	protein histidine kinase activity
HEC95_RS06105	COG0366	Alpha amylase catalytic
HEC95_RS06110	COG0450	alkyl hydroperoxide reductase
HEC95_RS06130	COG1862	Preprotein translocase
HEC95_RS06140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEC95_RS06170	COG4238	major outer membrane lipoprotein
HEC95_RS06180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEC95_RS06180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEC95_RS06195	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEC95_RS06200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HEC95_RS06205	COG0667	Aldo Keto reductase
HEC95_RS06215	COG0142	geranyltranstransferase activity
HEC95_RS06250	COG2188	Transcriptional regulator
HEC95_RS06280	COG2814	Major facilitator Superfamily
HEC95_RS06300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HEC95_RS06305	COG1845	cytochrome c oxidase, subunit III
HEC95_RS06310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEC95_RS06315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HEC95_RS06320	COG2223	nitrite transmembrane transporter activity
HEC95_RS06325	COG3056	Lipoprotein
HEC95_RS06330	COG0271	Belongs to the BolA IbaG family
HEC95_RS06350	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEC95_RS06360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HEC95_RS06365	COG1555	photosystem II stabilization
HEC95_RS06370	COG0824	Thioesterase
HEC95_RS06380	COG4533	DNA binding
HEC95_RS06395	COG1522	sequence-specific DNA binding
HEC95_RS06400	COG1132	(ABC) transporter
HEC95_RS06405	COG1132	(ABC) transporter
HEC95_RS06410	COG0347	Belongs to the P(II) protein family
HEC95_RS06415	COG0004	ammonium transporteR
HEC95_RS06420	COG1946	Acyl-CoA thioesterase
HEC95_RS06425	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HEC95_RS06430	COG3695	enzyme binding
HEC95_RS06440	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HEC95_RS06460	COG0110	maltose O-acetyltransferase activity
HEC95_RS06475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEC95_RS06480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEC95_RS06485	COG1309	transcriptional regulator
HEC95_RS06490	COG3264	Mechanosensitive ion channel
HEC95_RS06490	COG1196	nuclear chromosome segregation
HEC95_RS06495	COG5464	transposase or invertase
HEC95_RS06505	COG3923	Primosomal replication protein n
HEC95_RS06510	COG2832	Protein of unknown function (DUF454)
HEC95_RS06555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS06560	COG4651	solute:proton antiporter activity
HEC95_RS06560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HEC95_RS06565	COG2223	nitrite transmembrane transporter activity
HEC95_RS06580	COG3735	TraB family
HEC95_RS06590	COG2217	Heavy metal translocating P-type atpase
HEC95_RS06600	COG1585	Membrane protein implicated in regulation of membrane protease activity
HEC95_RS06605	COG0330	HflC and HflK could
HEC95_RS06610	COG4619	ABC transporter
HEC95_RS06615	COG0390	transport system, permease component
HEC95_RS06620	COG3118	belongs to the thioredoxin family
HEC95_RS06625	COG0300	oxidoreductase activity
HEC95_RS06630	COG2755	lipolytic protein G-D-S-L family
HEC95_RS06635	COG4181	ATPase activity
HEC95_RS06640	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HEC95_RS06650	COG1464	Belongs to the NlpA lipoprotein family
HEC95_RS06685	COG3960	tartronate-semialdehyde synthase activity
HEC95_RS06690	COG3622	Belongs to the hyi family
HEC95_RS06695	COG2084	Dehydrogenase
HEC95_RS06705	COG1953	Uracil, thiamine, allantoin
HEC95_RS06715	COG2233	PERMEase
HEC95_RS06720	COG1929	Belongs to the glycerate kinase type-1 family
HEC95_RS06725	COG3257	ureidoglycine aminohydrolase activity
HEC95_RS06730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HEC95_RS06735	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HEC95_RS06740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEC95_RS06745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEC95_RS06755	COG0549	Belongs to the carbamate kinase family
HEC95_RS06760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEC95_RS06765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEC95_RS06775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEC95_RS06795	COG1988	membrane-bound metal-dependent
HEC95_RS06800	COG2501	S4 domain
HEC95_RS06875	COG0463	Glycosyl transferase, family 2
HEC95_RS06880	COG2246	polysaccharide biosynthetic process
HEC95_RS06900	COG2207	Transcriptional regulator
HEC95_RS06905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEC95_RS06915	COG3059	membrane
HEC95_RS06925	COG1113	amino acid transport
HEC95_RS06930	COG0668	transmembrane transport
HEC95_RS06945	COG2315	Protein conserved in bacteria
HEC95_RS06975	COG4771	TonB-dependent receptor
HEC95_RS06980	COG2382	esterase
HEC95_RS06985	COG3251	PFAM MbtH domain protein
HEC95_RS06990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HEC95_RS06990	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HEC95_RS06995	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HEC95_RS07000	COG1120	ATPase activity
HEC95_RS07005	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEC95_RS07010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEC95_RS07020	COG4592	Periplasmic binding protein
HEC95_RS07025	COG1169	isochorismate synthase
HEC95_RS07030	COG1021	2,3-dihydroxybenzoate-AMP ligase
HEC95_RS07035	COG1535	isochorismatase
HEC95_RS07035	COG3433	isochorismatase activity
HEC95_RS07040	COG1028	Short-chain dehydrogenase reductase Sdr
HEC95_RS07050	COG1966	Carbon starvation protein
HEC95_RS07055	COG2879	small protein
HEC95_RS07060	COG0371	Dehydrogenase
HEC95_RS07065	COG0436	Aminotransferase
HEC95_RS07070	COG1475	DNA binding
HEC95_RS07075	COG3969	phosphoadenosine phosphosulfate
HEC95_RS07080	COG0583	DNA-binding transcription factor activity
HEC95_RS07085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HEC95_RS07105	COG0243	molybdopterin cofactor binding
HEC95_RS07125	COG1063	alcohol dehydrogenase
HEC95_RS07130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HEC95_RS07135	COG3719	Belongs to the RNase T2 family
HEC95_RS07140	COG0471	metal ion transport
HEC95_RS07155	COG3051	citrate lyase alpha subunit
HEC95_RS07160	COG2301	Belongs to the HpcH HpaI aldolase family
HEC95_RS07170	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HEC95_RS07175	COG3290	protein histidine kinase activity
HEC95_RS07180	COG4565	transcriptional regulatory protein
HEC95_RS07185	COG3069	C4-dicarboxylate transmembrane transporter activity
HEC95_RS07205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HEC95_RS07220	COG0583	DNA-binding transcription factor activity
HEC95_RS07235	COG1686	Belongs to the peptidase S11 family
HEC95_RS07245	COG0772	Belongs to the SEDS family
HEC95_RS07250	COG0768	penicillin binding
HEC95_RS07260	COG0799	negative regulation of ribosome biogenesis
HEC95_RS07280	COG1466	dna polymerase III delta subunit
HEC95_RS07310	COG3829	transcription factor binding
HEC95_RS07310	COG3290	protein histidine kinase activity
HEC95_RS07315	COG2888	peptidyl-tyrosine sulfation
HEC95_RS07330	COG2214	Heat shock protein DnaJ domain protein
HEC95_RS07340	COG2214	Heat shock protein DnaJ domain protein
HEC95_RS07345	COG0443	Heat shock 70 kDa protein
HEC95_RS07365	COG1126	abc transporter atp-binding protein
HEC95_RS07370	COG0765	amino acid transport
HEC95_RS07375	COG0765	amino acid transport
HEC95_RS07400	COG1702	phosphate starvation-inducible protein PhoH
HEC95_RS07410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HEC95_RS07455	COG0367	asparagine synthase
HEC95_RS07460	COG0647	UMP catabolic process
HEC95_RS07465	COG1846	Transcriptional regulator
HEC95_RS07465	COG1940	carbohydrate kinase activity
HEC95_RS07470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEC95_RS07510	COG1053	succinate dehydrogenase
HEC95_RS07515	COG0583	DNA-binding transcription factor activity
HEC95_RS07520	COG0735	belongs to the Fur family
HEC95_RS07535	COG0596	Alpha beta hydrolase
HEC95_RS07545	COG0033	Phosphoglucomutase
HEC95_RS07555	COG0531	amino acid
HEC95_RS07560	COG1982	Orn Lys Arg decarboxylase major
HEC95_RS07570	COG0745	RESPONSE REGULATOR receiver
HEC95_RS07575	COG2205	protein histidine kinase activity
HEC95_RS07620	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HEC95_RS07625	COG1984	allophanate hydrolase subunit 2
HEC95_RS07640	COG3180	Ammonia monooxygenase
HEC95_RS07660	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HEC95_RS07675	COG0567	Dehydrogenase, E1 component
HEC95_RS07680	COG0508	dehydrogenase complex catalyzes the overall conversion of
HEC95_RS07690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEC95_RS07695	COG1271	oxidase subunit
HEC95_RS07700	COG1294	oxidase, subunit
HEC95_RS07705	COG4890	Cyd operon protein YbgT
HEC95_RS07710	COG3790	cyd operon protein YbgE
HEC95_RS07715	COG0824	Thioesterase
HEC95_RS07720	COG0811	peptide transport
HEC95_RS07725	COG0848	biopolymer transport protein
HEC95_RS07730	COG3064	Membrane
HEC95_RS07740	COG2885	chlorophyll binding
HEC95_RS07745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HEC95_RS07795	COG1230	cation diffusion facilitator family transporter
HEC95_RS07805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HEC95_RS07810	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HEC95_RS07810	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HEC95_RS07815	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HEC95_RS07820	COG0583	DNA-binding transcription factor activity
HEC95_RS07825	COG0583	DNA-binding transcription factor activity
HEC95_RS07855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEC95_RS07860	COG1120	ATPase activity
HEC95_RS07870	COG2017	converts alpha-aldose to the beta-anomer
HEC95_RS07895	COG1119	ATPase activity
HEC95_RS07900	COG3585	molybdate ion transport
HEC95_RS07900	COG2005	Transcriptional regulator
HEC95_RS07910	COG0725	ABC transporter, periplasmic molybdate-binding protein
HEC95_RS07915	COG4149	molybdate abc transporter
HEC95_RS07925	COG0561	phosphatase activity
HEC95_RS07935	COG4677	pectinesterase activity
HEC95_RS07965	COG1881	PFAM PEBP family protein
HEC95_RS07990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HEC95_RS08020	COG0521	Mo-molybdopterin cofactor biosynthetic process
HEC95_RS08030	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEC95_RS08040	COG0670	Belongs to the BI1 family
HEC95_RS08060	COG0392	lysyltransferase activity
HEC95_RS08065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEC95_RS08070	COG3568	Endonuclease Exonuclease Phosphatase
HEC95_RS08080	COG0842	Transport permease protein
HEC95_RS08085	COG0842	Transport permease protein
HEC95_RS08090	COG1131	(ABC) transporter
HEC95_RS08100	COG1309	transcriptional regulator
HEC95_RS08105	COG0513	Belongs to the DEAD box helicase family
HEC95_RS08115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEC95_RS08125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HEC95_RS08135	COG0668	transmembrane transport
HEC95_RS08140	COG1126	abc transporter atp-binding protein
HEC95_RS08145	COG0765	amino acid transport
HEC95_RS08150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEC95_RS08165	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HEC95_RS08170	COG2194	sulfuric ester hydrolase activity
HEC95_RS08185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEC95_RS08190	COG1376	ErfK ybiS ycfS ynhG family protein
HEC95_RS08195	COG0488	(ABC) transporter
HEC95_RS08215	COG0561	phosphatase activity
HEC95_RS08220	COG1882	Formate acetyltransferase
HEC95_RS08225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEC95_RS08250	COG0747	negative chemotaxis
HEC95_RS08275	COG2301	Belongs to the HpcH HpaI aldolase family
HEC95_RS08290	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HEC95_RS08295	COG1960	acyl-CoA dehydrogenase activity
HEC95_RS08305	COG0583	DNA-binding transcription factor activity
HEC95_RS08310	COG2610	gluconate transmembrane transporter activity
HEC95_RS08315	COG2133	pyrroloquinoline quinone binding
HEC95_RS08320	COG2133	pyrroloquinoline quinone binding
HEC95_RS08325	COG0625	glutathione transferase activity
HEC95_RS08330	COG1686	Belongs to the peptidase S11 family
HEC95_RS08335	COG1349	DNA-binding transcription factor activity
HEC95_RS08340	COG0671	phosphoesterase, PA-phosphatase related
HEC95_RS08345	COG2814	Major facilitator Superfamily
HEC95_RS08350	COG0561	phosphatase activity
HEC95_RS08355	COG0738	Major facilitator superfamily
HEC95_RS08360	COG3226	Transcriptional regulator
HEC95_RS08400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HEC95_RS08405	COG3842	ATPase activity
HEC95_RS08410	COG1176	ABC-type spermidine putrescine transport system, permease component I
HEC95_RS08415	COG1177	transmembrane transport
HEC95_RS08445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEC95_RS08450	COG4160	amino acid transport
HEC95_RS08455	COG4215	(ABC) transporter
HEC95_RS08460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEC95_RS08465	COG1126	abc transporter atp-binding protein
HEC95_RS08480	COG3023	N-Acetylmuramoyl-L-alanine amidase
HEC95_RS08485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEC95_RS08490	COG0702	epimerase
HEC95_RS08495	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HEC95_RS08500	COG0028	Belongs to the TPP enzyme family
HEC95_RS08505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEC95_RS08515	COG2431	L-lysine efflux transmembrane transporter activity
HEC95_RS08520	COG3593	DNA synthesis involved in DNA repair
HEC95_RS08525	COG2990	Protein conserved in bacteria
HEC95_RS08530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEC95_RS08535	COG0577	efflux transmembrane transporter activity
HEC95_RS08535	COG1136	(ABC) transporter
HEC95_RS08540	COG1278	Cold shock
HEC95_RS08550	COG0542	response to heat
HEC95_RS08570	COG1335	isochorismatase
HEC95_RS08580	COG0583	DNA-binding transcription factor activity
HEC95_RS08600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEC95_RS08605	COG4988	ABC transporter
HEC95_RS08610	COG0492	ferredoxin-NADP+ reductase activity
HEC95_RS08630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HEC95_RS08640	COG0243	molybdopterin cofactor binding
HEC95_RS08645	COG0437	4 iron, 4 sulfur cluster binding
HEC95_RS08650	COG3302	dmso reductase anchor subunit
HEC95_RS08660	COG0531	amino acid
HEC95_RS08665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEC95_RS08680	COG1882	Formate acetyltransferase
HEC95_RS08685	COG2116	formate transmembrane transporter activity
HEC95_RS08690	COG1944	ATP diphosphatase activity
HEC95_RS08695	COG2323	membrane
HEC95_RS08710	COG0501	Belongs to the peptidase M48B family
HEC95_RS08720	COG0539	negative regulation of cytoplasmic translation
HEC95_RS08730	COG0658	competence protein
HEC95_RS08730	COG2333	competence protein COMEC
HEC95_RS08745	COG3214	Protein conserved in bacteria
HEC95_RS08760	COG3173	Aminoglycoside phosphotransferase
HEC95_RS08765	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HEC95_RS08770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HEC95_RS08780	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HEC95_RS08790	COG2989	Protein conserved in bacteria
HEC95_RS08795	COG3108	Peptidase M15
HEC95_RS08800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEC95_RS08810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HEC95_RS08815	COG0017	Asparaginyl-tRNA synthetase
HEC95_RS08820	COG1522	sequence-specific DNA binding
HEC95_RS08830	COG1115	amino acid carrier protein
HEC95_RS08840	COG0582	viral genome integration into host DNA
HEC95_RS08855	COG5301	cellulose 1,4-beta-cellobiosidase activity
HEC95_RS08885	COG2135	peptidase activity
HEC95_RS08905	COG0308	aminopeptidase N
HEC95_RS08920	COG3217	Mosc domain protein beta barrel domain protein
HEC95_RS08920	COG0633	Ferredoxin
HEC95_RS08930	COG0488	(ABC) transporter
HEC95_RS08935	COG2995	paraquat-inducible protein a
HEC95_RS08940	COG3008	intermembrane lipid transfer
HEC95_RS08940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HEC95_RS08945	COG3009	Protein conserved in bacteria
HEC95_RS08950	COG3130	regulation of translation
HEC95_RS08960	COG1067	ATP-dependent peptidase activity
HEC95_RS08980	COG3070	regulator of competence-specific genes
HEC95_RS08985	COG1289	transmembrane transporter activity
HEC95_RS08990	COG3304	Inner membrane component domain
HEC95_RS08995	COG0210	DNA helicase
HEC95_RS09010	COG1832	CoA-binding protein
HEC95_RS09025	COG1881	PFAM PEBP family protein
HEC95_RS09045	COG0670	Belongs to the BI1 family
HEC95_RS09095	COG2205	protein histidine kinase activity
HEC95_RS09100	COG0745	RESPONSE REGULATOR receiver
HEC95_RS09115	COG2368	4-hydroxyphenylacetate
HEC95_RS09120	COG1846	Transcriptional regulator
HEC95_RS09130	COG1012	belongs to the aldehyde dehydrogenase family
HEC95_RS09135	COG3384	dioxygenase
HEC95_RS09145	COG3971	2-oxopent-4-enoate hydratase activity
HEC95_RS09190	COG4232	protein-disulfide reductase activity
HEC95_RS09195	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HEC95_RS09195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HEC95_RS09200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEC95_RS09220	COG3729	General stress protein
HEC95_RS09225	COG1309	transcriptional regulator
HEC95_RS09245	COG1702	phosphate starvation-inducible protein PhoH
HEC95_RS09250	COG1737	Transcriptional regulator
HEC95_RS09255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEC95_RS09275	COG2814	Major facilitator Superfamily
HEC95_RS09280	COG0673	inositol 2-dehydrogenase activity
HEC95_RS09315	COG3157	Type VI secretion system effector, Hcp
HEC95_RS09340	COG3209	COG3209 Rhs family protein
HEC95_RS09390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HEC95_RS09400	COG1418	mRNA catabolic process
HEC95_RS09405	COG0270	DNA (cytosine-5-)-methyltransferase activity
HEC95_RS09410	COG3727	T/G mismatch-specific endonuclease activity
HEC95_RS09415	COG0697	spore germination
HEC95_RS09420	COG2354	Protein conserved in bacteria
HEC95_RS09425	COG5475	Uncharacterized small protein (DUF2158)
HEC95_RS09530	COG0425	Belongs to the sulfur carrier protein TusA family
HEC95_RS09610	COG2197	response regulator
HEC95_RS09625	COG2197	response regulator
HEC95_RS09670	COG3012	SEC-C Motif Domain Protein
HEC95_RS09670	COG3318	Belongs to the UPF0149 family
HEC95_RS09675	COG0814	amino acid
HEC95_RS09685	COG1528	Iron-storage protein
HEC95_RS09700	COG1528	Iron-storage protein
HEC95_RS09805	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HEC95_RS09820	COG3102	Protein conserved in bacteria
HEC95_RS09840	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HEC95_RS09845	COG1801	Protein of unknown function DUF72
HEC95_RS09850	COG1335	isochorismatase
HEC95_RS09860	COG0494	nUDIX hydrolase
HEC95_RS09895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HEC95_RS09905	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HEC95_RS09910	COG0739	heme binding
HEC95_RS09915	COG1560	Kdo2-lipid A biosynthetic process
HEC95_RS09925	COG1737	Transcriptional regulator
HEC95_RS09930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEC95_RS09935	COG0129	dihydroxy-acid dehydratase activity
HEC95_RS09940	COG0800	Aldolase
HEC95_RS09950	COG3141	response to X-ray
HEC95_RS09960	COG2979	Protein of unknown function (DUF533)
HEC95_RS09965	COG1770	oligopeptidase
HEC95_RS09970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HEC95_RS09975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HEC95_RS09985	COG2372	response to copper ion
HEC95_RS09990	COG1276	copper resistance
HEC95_RS10010	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HEC95_RS10130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HEC95_RS10230	COG0454	-acetyltransferase
HEC95_RS10240	COG5562	phage envelope protein
HEC95_RS10275	COG3008	intermembrane lipid transfer
HEC95_RS10280	COG2995	paraquat-inducible protein a
HEC95_RS10285	COG1956	GAF domain-containing protein
HEC95_RS10305	COG2814	Major facilitator Superfamily
HEC95_RS10310	COG1414	Transcriptional regulator
HEC95_RS10340	COG0768	penicillin binding
HEC95_RS10345	COG2226	methyltransferase
HEC95_RS10360	COG3716	PTS system mannose fructose sorbose family IID component
HEC95_RS10365	COG3715	PTS system
HEC95_RS10370	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEC95_RS10370	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS10375	COG1253	flavin adenine dinucleotide binding
HEC95_RS10380	COG2200	EAL domain
HEC95_RS10385	COG1760	l-serine dehydratase
HEC95_RS10405	COG0251	oxidation-reduction process
HEC95_RS10410	COG1199	ATP-dependent helicase activity
HEC95_RS10420	COG3065	identical protein binding
HEC95_RS10430	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HEC95_RS10440	COG2894	cell division
HEC95_RS10455	COG0179	Fumarylacetoacetate (FAA) hydrolase
HEC95_RS10495	COG2719	SpoVR family
HEC95_RS10515	COG1619	proteins homologs of microcin C7 resistance protein MccF
HEC95_RS10540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HEC95_RS10550	COG1294	oxidase, subunit
HEC95_RS10555	COG1271	oxidase subunit
HEC95_RS10560	COG1773	rubredoxin
HEC95_RS10565	COG1999	signal sequence binding
HEC95_RS10570	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEC95_RS10575	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HEC95_RS10585	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HEC95_RS10600	COG0012	GTP binding
HEC95_RS10615	COG0659	secondary active sulfate transmembrane transporter activity
HEC95_RS10665	COG0387	Pfam Sodium calcium exchanger
HEC95_RS10670	COG4572	Cation transport regulator
HEC95_RS10675	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HEC95_RS10680	COG4932	domain protein
HEC95_RS10685	COG2197	response regulator
HEC95_RS10690	COG3850	Histidine kinase
HEC95_RS10695	COG2223	nitrite transmembrane transporter activity
HEC95_RS10700	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEC95_RS10705	COG1140	nitrate reductase beta subunit
HEC95_RS10710	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HEC95_RS10715	COG2181	nitrate reductase activity
HEC95_RS10760	COG0788	formyltetrahydrofolate deformylase activity
HEC95_RS10770	COG1752	Esterase of the alpha-beta hydrolase superfamily
HEC95_RS10775	COG0745	RESPONSE REGULATOR receiver
HEC95_RS10780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HEC95_RS10795	COG1454	alcohol dehydrogenase
HEC95_RS10795	COG1012	belongs to the aldehyde dehydrogenase family
HEC95_RS10800	COG2095	MarC family integral membrane protein
HEC95_RS10830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HEC95_RS10850	COG2350	Protein conserved in bacteria
HEC95_RS10875	COG0727	PFAM Uncharacterised protein family (UPF0153)
HEC95_RS10885	COG3546	catalase activity
HEC95_RS10890	COG3685	Protein conserved in bacteria
HEC95_RS10895	COG3685	Protein conserved in bacteria
HEC95_RS10900	COG3729	General stress protein
HEC95_RS10915	COG0135	phosphoribosylanthranilate isomerase activity
HEC95_RS10915	COG0134	indole-3-glycerol-phosphate synthase activity
HEC95_RS10940	COG0009	L-threonylcarbamoyladenylate synthase
HEC95_RS10955	COG1028	Short-chain dehydrogenase reductase Sdr
HEC95_RS10960	COG0616	signal peptide processing
HEC95_RS11000	COG0671	phosphoesterase, PA-phosphatase related
HEC95_RS11005	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HEC95_RS11010	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HEC95_RS11030	COG1349	DNA-binding transcription factor activity
HEC95_RS11040	COG5001	Diguanylate cyclase
HEC95_RS11050	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEC95_RS11050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEC95_RS11120	COG1192	Involved in chromosome partitioning
HEC95_RS11430	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HEC95_RS11435	COG1842	Phage shock protein A
HEC95_RS11445	COG1983	PspC domain protein
HEC95_RS11455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEC95_RS11460	COG3106	COG3106 Predicted ATPase
HEC95_RS11480	COG4948	Mandelate Racemase Muconate Lactonizing
HEC95_RS11485	COG2866	Carboxypeptidase
HEC95_RS11490	COG4166	transmembrane transport
HEC95_RS11500	COG0583	DNA-binding transcription factor activity
HEC95_RS11505	COG0656	L-ascorbic acid biosynthetic process
HEC95_RS11510	COG1028	Short-chain dehydrogenase reductase Sdr
HEC95_RS11515	COG1309	transcriptional regulator
HEC95_RS11550	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEC95_RS11570	COG0668	transmembrane transport
HEC95_RS11575	COG3182	Iron-regulated membrane protein
HEC95_RS11595	COG2840	Smr protein MutS2
HEC95_RS11600	COG0840	transmembrane signaling receptor activity
HEC95_RS11610	COG0513	Belongs to the DEAD box helicase family
HEC95_RS11730	COG2076	Multidrug Resistance protein
HEC95_RS11740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HEC95_RS11740	COG0674	pyruvate-flavodoxin oxidoreductase activity
HEC95_RS11740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HEC95_RS11740	COG1013	pyruvate-flavodoxin oxidoreductase activity
HEC95_RS11750	COG3042	response to heat
HEC95_RS11755	COG3187	Heat shock protein
HEC95_RS11760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEC95_RS11765	COG2911	Protein conserved in bacteria
HEC95_RS11775	COG3784	Protein of unknown function (DUF1318)
HEC95_RS11790	COG1643	Atp-dependent helicase
HEC95_RS11795	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HEC95_RS11800	COG3038	cytochrome b561
HEC95_RS11805	COG0500	methyltransferase
HEC95_RS11815	COG0765	amino acid transport
HEC95_RS11825	COG0765	amino acid transport
HEC95_RS11830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HEC95_RS11865	COG0840	transmembrane signaling receptor activity
HEC95_RS11870	COG0583	DNA-binding transcription factor activity
HEC95_RS11875	COG5383	Protein conserved in bacteria
HEC95_RS11880	COG2272	Belongs to the type-B carboxylesterase lipase family
HEC95_RS11890	COG2353	YceI-like domain
HEC95_RS11900	COG1063	alcohol dehydrogenase
HEC95_RS11905	COG2271	Major facilitator Superfamily
HEC95_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
HEC95_RS11925	COG1349	DNA-binding transcription factor activity
HEC95_RS11930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HEC95_RS11935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS11940	COG0434	BtpA family
HEC95_RS11945	COG3775	system Galactitol-specific IIC component
HEC95_RS11950	COG3414	Phosphotransferase system galactitol-specific IIB component
HEC95_RS11960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEC95_RS11965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEC95_RS11970	COG1275	C4-dicarboxylate transporter malic acid transport protein
HEC95_RS11975	COG0500	methyltransferase
HEC95_RS11985	COG3135	benzoate transporter
HEC95_RS11990	COG1396	sequence-specific DNA binding
HEC95_RS11995	COG0826	peptidase U32
HEC95_RS12020	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HEC95_RS12025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEC95_RS12065	COG3238	Protein conserved in bacteria
HEC95_RS12075	COG2130	NADP-dependent
HEC95_RS12080	COG1802	Transcriptional regulator
HEC95_RS12085	COG4772	TonB-dependent receptor
HEC95_RS12120	COG2181	nitrate reductase activity
HEC95_RS12125	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HEC95_RS12130	COG1140	nitrate reductase beta subunit
HEC95_RS12135	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEC95_RS12175	COG0437	4 iron, 4 sulfur cluster binding
HEC95_RS12180	COG2864	formate dehydrogenase
HEC95_RS12185	COG1064	alcohol dehydrogenase
HEC95_RS12205	COG1764	response to oxidative stress
HEC95_RS12220	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEC95_RS12235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HEC95_RS12240	COG1757	Na H antiporter
HEC95_RS12245	COG1609	Transcriptional regulator
HEC95_RS12260	COG0251	oxidation-reduction process
HEC95_RS12265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEC95_RS12290	COG2271	Major facilitator Superfamily
HEC95_RS12295	COG1063	alcohol dehydrogenase
HEC95_RS12300	COG2186	Transcriptional regulator
HEC95_RS12310	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HEC95_RS12315	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HEC95_RS12340	COG1773	rubredoxin
HEC95_RS12365	COG3781	membrane
HEC95_RS12380	COG1012	belongs to the aldehyde dehydrogenase family
HEC95_RS12385	COG0583	DNA-binding transcription factor activity
HEC95_RS12420	COG2814	Major facilitator Superfamily
HEC95_RS12430	COG3111	PFAM Bacterial OB fold (BOF) protein
HEC95_RS12435	COG1546	Belongs to the CinA family
HEC95_RS12440	COG3729	General stress protein
HEC95_RS12450	COG4221	oxidoreductase activity
HEC95_RS12455	COG1802	Transcriptional regulator
HEC95_RS12465	COG0246	Mannitol dehydrogenase
HEC95_RS12470	COG0477	Major facilitator Superfamily
HEC95_RS12475	COG1063	alcohol dehydrogenase
HEC95_RS12495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEC95_RS12510	COG0243	molybdopterin cofactor binding
HEC95_RS12515	COG0243	molybdopterin cofactor binding
HEC95_RS12520	COG0437	4 iron, 4 sulfur cluster binding
HEC95_RS12525	COG3302	dmso reductase anchor subunit
HEC95_RS12565	COG1940	carbohydrate kinase activity
HEC95_RS12570	COG0583	DNA-binding transcription factor activity
HEC95_RS12575	COG2814	Major facilitator Superfamily
HEC95_RS12585	COG3591	Belongs to the peptidase S1B family
HEC95_RS12600	COG0628	permease
HEC95_RS12605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HEC95_RS12610	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HEC95_RS12620	COG0531	amino acid
HEC95_RS12625	COG3136	membrane protein required for alginate biosynthesis
HEC95_RS12630	COG0745	RESPONSE REGULATOR receiver
HEC95_RS12635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HEC95_RS12640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEC95_RS12645	COG2205	protein histidine kinase activity
HEC95_RS12670	COG5339	Protein conserved in bacteria
HEC95_RS12690	COG0673	inositol 2-dehydrogenase activity
HEC95_RS12740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEC95_RS12750	COG0625	glutathione transferase activity
HEC95_RS12770	COG3895	Periplasmic Protein
HEC95_RS12795	COG1566	PFAM secretion protein HlyD family protein
HEC95_RS12810	COG4989	oxidoreductase activity
HEC95_RS12815	COG3313	Fe-S protein
HEC95_RS12820	COG1309	transcriptional regulator
HEC95_RS12825	COG1902	pentaerythritol trinitrate reductase activity
HEC95_RS12840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HEC95_RS12845	COG0791	NLP P60 protein
HEC95_RS12865	COG0583	DNA-binding transcription factor activity
HEC95_RS12870	COG2814	Major facilitator Superfamily
HEC95_RS12875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HEC95_RS12880	COG0307	riboflavin synthase, alpha
HEC95_RS13060	COG0789	Transcriptional regulator
HEC95_RS13065	COG3272	Protein of unknown function (DUF1722)
HEC95_RS13100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS13110	COG2267	carboxylic ester hydrolase activity
HEC95_RS13115	COG0531	amino acid
HEC95_RS13135	COG1376	ErfK ybiS ycfS ynhG family protein
HEC95_RS13150	COG0719	Fe-S assembly protein
HEC95_RS13155	COG0396	ATPase activity
HEC95_RS13160	COG0719	Fe-S assembly protein
HEC95_RS13165	COG0316	Belongs to the HesB IscA family
HEC95_RS13180	COG2050	protein possibly involved in aromatic compounds catabolism
HEC95_RS13185	COG0247	lactate metabolic process
HEC95_RS13185	COG0277	FAD linked oxidase domain protein
HEC95_RS13190	COG0628	permease
HEC95_RS13205	COG0738	Major facilitator superfamily
HEC95_RS13210	COG2271	Major facilitator Superfamily
HEC95_RS13225	COG4670	ketone body catabolic process
HEC95_RS13230	COG1960	acyl-CoA dehydrogenase activity
HEC95_RS13235	COG1917	Cupin 2, conserved barrel domain protein
HEC95_RS13235	COG2207	Transcriptional regulator
HEC95_RS13240	COG2086	electron transfer activity
HEC95_RS13245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HEC95_RS13250	COG0644	oxidoreductase
HEC95_RS13255	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HEC95_RS13260	COG0318	PFAM AMP-dependent synthetase and ligase
HEC95_RS13265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEC95_RS13265	COG0574	Belongs to the PEP-utilizing enzyme family
HEC95_RS13280	COG4256	Hemin uptake protein
HEC95_RS13295	COG0791	NLP P60 protein
HEC95_RS13305	COG0386	Belongs to the glutathione peroxidase family
HEC95_RS13380	COG3137	Salt-induced outer membrane protein
HEC95_RS13385	COG1105	Belongs to the carbohydrate kinase PfkB family
HEC95_RS13395	COG3001	Fructosamine kinase
HEC95_RS13405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HEC95_RS13410	COG1988	membrane-bound metal-dependent
HEC95_RS13425	COG0753	catalase activity
HEC95_RS13435	COG1486	melibiose metabolic process
HEC95_RS13440	COG1917	Cupin 2, conserved barrel domain protein
HEC95_RS13440	COG2169	Transcriptional regulator
HEC95_RS13445	COG1447	Phosphotransferase system cellobiose-specific component IIA
HEC95_RS13450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HEC95_RS13455	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HEC95_RS13460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HEC95_RS13470	COG0322	excinuclease ABC activity
HEC95_RS13475	COG3678	ATP-independent chaperone mediated protein folding
HEC95_RS13510	COG0494	nUDIX hydrolase
HEC95_RS13525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEC95_RS13535	COG0778	Nitroreductase
HEC95_RS13540	COG0616	signal peptide processing
HEC95_RS13545	COG0252	asparaginase activity
HEC95_RS13550	COG1335	isochorismatase
HEC95_RS13555	COG2814	Major facilitator Superfamily
HEC95_RS13560	COG1349	DNA-binding transcription factor activity
HEC95_RS13565	COG0667	Aldo Keto reductase
HEC95_RS13570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS13575	COG0191	fructose-bisphosphate aldolase activity
HEC95_RS13580	COG1063	alcohol dehydrogenase
HEC95_RS13585	COG2271	Major facilitator Superfamily
HEC95_RS13595	COG3139	Protein of unknown function (DUF1315)
HEC95_RS13615	COG0656	L-ascorbic acid biosynthetic process
HEC95_RS13620	COG0641	radical SAM
HEC95_RS13625	COG3713	MltA-interacting MipA family protein
HEC95_RS13630	COG2766	serine protein kinase
HEC95_RS13645	COG2199	diguanylate cyclase activity
HEC95_RS13650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEC95_RS13665	COG2207	Transcriptional regulator
HEC95_RS13670	COG2807	transmembrane transport
HEC95_RS13675	COG3189	MarR family transcriptional regulator
HEC95_RS13685	COG3042	response to heat
HEC95_RS13695	COG2261	transglycosylase associated protein
HEC95_RS13710	COG3615	Tellurite resistance protein tehB
HEC95_RS13720	COG1605	Chorismate mutase
HEC95_RS13730	COG0789	Transcriptional regulator
HEC95_RS13745	COG3443	Belongs to the bacterial solute-binding protein 9 family
HEC95_RS13760	COG0668	transmembrane transport
HEC95_RS13765	COG1124	(ABC) transporter
HEC95_RS13795	COG3038	cytochrome b561
HEC95_RS13805	COG0071	Belongs to the small heat shock protein (HSP20) family
HEC95_RS13860	COG0538	isocitrate dehydrogenase activity
HEC95_RS13890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEC95_RS13905	COG2850	peptidyl-arginine hydroxylation
HEC95_RS13935	COG1177	transmembrane transport
HEC95_RS13955	COG4591	ABC-type transport system involved in lipoprotein release permease component
HEC95_RS13960	COG1136	(ABC) transporter
HEC95_RS13965	COG4591	ABC-type transport system involved in lipoprotein release permease component
HEC95_RS13970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEC95_RS13975	COG1388	LysM domain
HEC95_RS13975	COG1376	ErfK ybiS ycfS ynhG family protein
HEC95_RS13985	COG1309	transcriptional regulator
HEC95_RS13990	COG3134	Outer membrane lipoprotein
HEC95_RS13995	COG1252	NADH dehydrogenase
HEC95_RS14020	COG5633	Lipoprotein
HEC95_RS14025	COG0537	adenosine 5'-monophosphoramidase activity
HEC95_RS14030	COG4773	Receptor
HEC95_RS14040	COG0084	hydrolase, TatD family'
HEC95_RS14045	COG0470	DNA polymerase III
HEC95_RS14055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEC95_RS14060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HEC95_RS14065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HEC95_RS14125	COG1530	ribonuclease E activity
HEC95_RS14215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEC95_RS14225	COG2999	glutathione oxidoreductase activity
HEC95_RS14260	COG3038	cytochrome b561
HEC95_RS14275	COG1560	Kdo2-lipid A biosynthetic process
HEC95_RS14290	COG5645	(Lipo)protein
HEC95_RS14310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEC95_RS14365	COG3381	protein complex oligomerization
HEC95_RS14400	COG3547	Transposase (IS116 IS110 IS902 family)
HEC95_RS14420	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HEC95_RS14440	COG3778	Protein conserved in bacteria
HEC95_RS14445	COG3299	homolog of phage Mu protein gp47
HEC95_RS14485	COG4386	tail sheath protein
HEC95_RS14535	COG4626	Terminase
HEC95_RS14535	COG1802	Transcriptional regulator
HEC95_RS14555	COG3179	chitinase
HEC95_RS14580	COG0484	heat shock protein binding
HEC95_RS14585	COG1403	HNH endonuclease
HEC95_RS14595	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HEC95_RS14600	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HEC95_RS14620	COG3646	Phage regulatory protein
HEC95_RS14640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEC95_RS14655	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HEC95_RS14725	COG0582	viral genome integration into host DNA
HEC95_RS14900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEC95_RS14925	COG0534	Mate efflux family protein
HEC95_RS14960	COG1122	ATPase activity
HEC95_RS15090	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HEC95_RS15120	COG1012	belongs to the aldehyde dehydrogenase family
HEC95_RS15120	COG1454	alcohol dehydrogenase
HEC95_RS15125	COG4656	Part of a membrane complex involved in electron transport
HEC95_RS15160	COG1289	transmembrane transporter activity
HEC95_RS15200	COG2925	Exonuclease
HEC95_RS15205	COG0531	amino acid
HEC95_RS15215	COG0583	DNA-binding transcription factor activity
HEC95_RS15220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEC95_RS15315	COG2244	polysaccharide biosynthetic process
HEC95_RS15320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEC95_RS15325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEC95_RS15340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HEC95_RS15385	COG2327	Polysaccharide pyruvyl transferase
HEC95_RS15390	COG2244	polysaccharide biosynthetic process
HEC95_RS15395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HEC95_RS15410	COG0297	glycogen (starch) synthase activity
HEC95_RS15420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEC95_RS15425	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HEC95_RS15430	COG0110	maltose O-acetyltransferase activity
HEC95_RS15435	COG1216	Glycosyl transferase, family 2
HEC95_RS15445	COG0438	transferase activity, transferring glycosyl groups
HEC95_RS15450	COG1045	serine acetyltransferase
HEC95_RS15455	COG0463	Glycosyl transferase, family 2
HEC95_RS15475	COG1253	flavin adenine dinucleotide binding
HEC95_RS15480	COG2982	Protein involved in outer membrane biogenesis
HEC95_RS15495	COG3447	MASE1 domain protein
HEC95_RS15495	COG5001	Diguanylate cyclase
HEC95_RS15495	COG5002	protein histidine kinase activity
HEC95_RS15500	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEC95_RS15505	COG0443	Heat shock 70 kDa protein
HEC95_RS15535	COG2205	protein histidine kinase activity
HEC95_RS15540	COG0745	RESPONSE REGULATOR receiver
HEC95_RS15585	COG1830	Aldolase
HEC95_RS15590	COG2211	Major facilitator Superfamily
HEC95_RS15595	COG1397	ADP-ribosylglycohydrolase
HEC95_RS15600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS15605	COG2188	Transcriptional regulator
HEC95_RS15620	COG5455	response to cobalt ion
HEC95_RS15625	COG3539	Fimbrial protein
HEC95_RS15630	COG3188	usher protein
HEC95_RS15635	COG3121	Chaperone
HEC95_RS15660	COG4808	Protein conserved in bacteria
HEC95_RS15670	COG4807	Protein conserved in bacteria
HEC95_RS15680	COG3275	phosphorelay sensor kinase activity
HEC95_RS15695	COG1174	glycine betaine transport
HEC95_RS15700	COG1125	glycine betaine transport
HEC95_RS15705	COG1174	glycine betaine transport
HEC95_RS15710	COG1732	Glycine betaine
HEC95_RS15720	COG0277	FAD linked oxidase domain protein
HEC95_RS15725	COG1686	Belongs to the peptidase S11 family
HEC95_RS15735	COG0586	Pfam SNARE associated Golgi protein
HEC95_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
HEC95_RS15745	COG1538	Outer membrane efflux protein
HEC95_RS15760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HEC95_RS15765	COG0625	glutathione transferase activity
HEC95_RS15780	COG2271	Major facilitator Superfamily
HEC95_RS15795	COG1346	cytolysis
HEC95_RS15805	COG2949	membrane
HEC95_RS15815	COG0493	'glutamate synthase
HEC95_RS15845	COG2311	Membrane
HEC95_RS15865	COG1760	l-serine dehydratase
HEC95_RS15870	COG0560	Phosphoserine phosphatase
HEC95_RS15875	COG2271	Major facilitator Superfamily
HEC95_RS15880	COG4771	TonB-dependent receptor
HEC95_RS15885	COG0833	amino acid
HEC95_RS15890	COG0583	DNA-binding transcription factor activity
HEC95_RS15895	COG2855	membrane
HEC95_RS15905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEC95_RS15905	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HEC95_RS15905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEC95_RS15910	COG1105	Belongs to the carbohydrate kinase PfkB family
HEC95_RS15945	COG0523	cobalamin synthesis protein
HEC95_RS15950	COG0671	phosphoesterase, PA-phosphatase related
HEC95_RS15955	COG0791	NLP P60 protein
HEC95_RS15960	COG2200	EAL domain
HEC95_RS15965	COG4166	transmembrane transport
HEC95_RS15970	COG4174	ABC transporter (Permease)
HEC95_RS15975	COG4239	(ABC) transporter, permease
HEC95_RS15980	COG4172	Belongs to the ABC transporter superfamily
HEC95_RS15990	COG2814	Major facilitator Superfamily
HEC95_RS16000	COG1061	Type III restriction enzyme res subunit
HEC95_RS16070	COG2197	response regulator
HEC95_RS16075	COG4235	cytochrome complex assembly
HEC95_RS16075	COG3088	subunit of a heme lyase
HEC95_RS16085	COG1138	Cytochrome C-type biogenesis protein
HEC95_RS16095	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HEC95_RS16100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HEC95_RS16105	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HEC95_RS16115	COG3005	denitrification pathway
HEC95_RS16120	COG3043	anaerobic respiration
HEC95_RS16125	COG0348	domain, Protein
HEC95_RS16130	COG0437	4 iron, 4 sulfur cluster binding
HEC95_RS16140	COG3062	negative regulation of establishment of protein localization
HEC95_RS16145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HEC95_RS16145	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HEC95_RS16155	COG4615	Cyclic peptide transporter
HEC95_RS16180	COG2198	Histidine kinase
HEC95_RS16180	COG0642	Histidine kinase
HEC95_RS16200	COG4948	Mandelate Racemase Muconate Lactonizing
HEC95_RS16230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEC95_RS16235	COG2814	Major facilitator Superfamily
HEC95_RS16240	COG0583	DNA-binding transcription factor activity
HEC95_RS16245	COG0584	glycerophosphoryl diester phosphodiesterase
HEC95_RS16250	COG2271	Major facilitator Superfamily
HEC95_RS16255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEC95_RS16265	COG0247	lactate metabolic process
HEC95_RS16295	COG1414	Transcriptional regulator
HEC95_RS16385	COG1169	isochorismate synthase
HEC95_RS16390	COG4575	ribosome binding
HEC95_RS16395	COG2153	protein acetylation
HEC95_RS16405	COG0784	Response regulator, receiver
HEC95_RS16405	COG0835	chemotaxis
HEC95_RS16410	COG2304	oxidoreductase activity
HEC95_RS16425	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HEC95_RS16430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HEC95_RS16440	COG0839	Belongs to the complex I subunit 6 family
HEC95_RS16490	COG0583	DNA-binding transcription factor activity
HEC95_RS16495	COG0436	Aminotransferase
HEC95_RS16505	COG0471	metal ion transport
HEC95_RS16505	COG0490	domain, Protein
HEC95_RS16510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HEC95_RS16535	COG1288	antiporter activity
HEC95_RS16540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEC95_RS16545	COG3959	Transketolase, thiamine diphosphate binding domain
HEC95_RS16550	COG3037	sugar-specific permease SgaT UlaA
HEC95_RS16560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS16565	COG1609	Transcriptional regulator
HEC95_RS16575	COG0622	Phosphoesterase
HEC95_RS16580	COG0625	glutathione transferase activity
HEC95_RS16585	COG0625	glutathione transferase activity
HEC95_RS16590	COG1090	epimerase
HEC95_RS16625	COG0833	amino acid
HEC95_RS16630	COG3457	Alanine racemase
HEC95_RS16635	COG0531	amino acid
HEC95_RS16645	COG3829	transcription factor binding
HEC95_RS16650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEC95_RS16655	COG1286	toxin biosynthetic process
HEC95_RS16660	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HEC95_RS16665	COG0285	dihydrofolate synthase activity
HEC95_RS16675	COG0586	Pfam SNARE associated Golgi protein
HEC95_RS16685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEC95_RS16710	COG3423	Transcriptional regulator
HEC95_RS16730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HEC95_RS16745	COG3101	peptidyl-lysine hydroxylation
HEC95_RS16750	COG0730	response to heat
HEC95_RS16775	COG2062	phosphohistidine phosphatase, SixA
HEC95_RS16790	COG3691	Protein conserved in bacteria
HEC95_RS16805	COG2116	formate transmembrane transporter activity
HEC95_RS16820	COG2246	polysaccharide biosynthetic process
HEC95_RS16825	COG0463	Glycosyl transferase, family 2
HEC95_RS16880	COG1560	Kdo2-lipid A biosynthetic process
HEC95_RS16890	COG0436	Aminotransferase
HEC95_RS16905	COG3961	Belongs to the TPP enzyme family
HEC95_RS16910	COG0667	Aldo Keto reductase
HEC95_RS16925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEC95_RS16930	COG2200	EAL domain
HEC95_RS16930	COG2199	diguanylate cyclase activity
HEC95_RS16945	COG3415	Transposase
HEC95_RS16950	COG3415	Transposase
HEC95_RS16980	COG0583	DNA-binding transcription factor activity
HEC95_RS16990	COG2211	Major facilitator Superfamily
HEC95_RS16995	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEC95_RS17005	COG0583	DNA-binding transcription factor activity
HEC95_RS17010	COG0385	Bile acid
HEC95_RS17015	COG3530	Putative quorum-sensing-regulated virulence factor
HEC95_RS17040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS17095	COG4208	sulfate ABC transporter
HEC95_RS17115	COG2837	iron assimilation
HEC95_RS17250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEC95_RS17260	COG5342	invasion associated locus B
HEC95_RS17275	COG0493	'glutamate synthase
HEC95_RS17275	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HEC95_RS17280	COG3850	Histidine kinase
HEC95_RS17285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEC95_RS17295	COG1393	Belongs to the ArsC family
HEC95_RS17315	COG2321	neutral zinc metallopeptidase
HEC95_RS17325	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HEC95_RS17330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEC95_RS17335	COG2716	regulation of RNA biosynthetic process
HEC95_RS17340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEC95_RS17345	COG1929	Belongs to the glycerate kinase type-1 family
HEC95_RS17350	COG2610	gluconate transmembrane transporter activity
HEC95_RS17355	COG3835	regulator
HEC95_RS17360	COG0628	permease
HEC95_RS17370	COG1393	Belongs to the ArsC family
HEC95_RS17380	COG2233	PERMEase
HEC95_RS17395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEC95_RS17410	COG2200	EAL domain
HEC95_RS17445	COG0517	IMP dehydrogenase activity
HEC95_RS17445	COG0516	GMP reductase activity
HEC95_RS17485	COG1645	bacterial-type flagellum-dependent swarming motility
HEC95_RS17500	COG2976	Protein conserved in bacteria
HEC95_RS17540	COG0437	4 iron, 4 sulfur cluster binding
HEC95_RS17545	COG0243	molybdopterin cofactor binding
HEC95_RS17550	COG4953	penicillin-binding protein 1C
HEC95_RS17555	COG2373	Large extracellular alpha-helical protein
HEC95_RS17560	COG2897	thiosulfate sulfurtransferase activity
HEC95_RS17585	COG2975	iron-sulfur cluster assembly
HEC95_RS17590	COG0633	Ferredoxin
HEC95_RS17610	COG0822	iron-sulfur transferase activity
HEC95_RS17655	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HEC95_RS17665	COG3711	transcriptional antiterminator
HEC95_RS17670	COG2814	Major facilitator Superfamily
HEC95_RS17680	COG1017	nitric oxide dioxygenase activity
HEC95_RS17680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEC95_RS17685	COG3710	Transcriptional regulator
HEC95_RS17690	COG0531	amino acid
HEC95_RS17700	COG3104	oligopeptide transport
HEC95_RS17705	COG0347	Belongs to the P(II) protein family
HEC95_RS17710	COG2204	response regulator
HEC95_RS17715	COG3170	Tfp pilus assembly protein FimV
HEC95_RS17720	COG2205	protein histidine kinase activity
HEC95_RS17745	COG0560	Phosphoserine phosphatase
HEC95_RS17750	COG1263	PTS System
HEC95_RS17750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEC95_RS17760	COG1737	Transcriptional regulator
HEC95_RS17765	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEC95_RS17770	COG2223	nitrite transmembrane transporter activity
HEC95_RS17775	COG0583	DNA-binding transcription factor activity
HEC95_RS17780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HEC95_RS17820	COG3086	response to oxidative stress
HEC95_RS17845	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HEC95_RS17855	COG0513	Belongs to the DEAD box helicase family
HEC95_RS17860	COG0583	DNA-binding transcription factor activity
HEC95_RS17880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEC95_RS17885	COG3118	belongs to the thioredoxin family
HEC95_RS17900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEC95_RS17905	COG5544	Lipoprotein
HEC95_RS17910	COG0477	Major facilitator Superfamily
HEC95_RS17940	COG0542	response to heat
HEC95_RS17955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HEC95_RS17960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEC95_RS17970	COG1605	Chorismate mutase
HEC95_RS17970	COG0077	Prephenate dehydratase
HEC95_RS17980	COG0287	Prephenate dehydrogenase
HEC95_RS17980	COG1605	Chorismate mutase
HEC95_RS17995	COG2199	diguanylate cyclase activity
HEC95_RS18020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEC95_RS18025	COG4137	Cytochrome C assembly protein
HEC95_RS18030	COG4536	flavin adenine dinucleotide binding
HEC95_RS18050	COG0497	DNA recombination
HEC95_RS18065	COG2867	negative regulation of translational initiation
HEC95_RS18090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEC95_RS18140	COG2819	hydrolase of the alpha beta superfamily
HEC95_RS18160	COG2990	Protein conserved in bacteria
HEC95_RS18170	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HEC95_RS18175	COG0642	Histidine kinase
HEC95_RS18205	COG0579	oxidoreductase
HEC95_RS18210	COG1012	belongs to the aldehyde dehydrogenase family
HEC95_RS18215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEC95_RS18220	COG1113	amino acid transport
HEC95_RS18225	COG1802	Transcriptional regulator
HEC95_RS18230	COG1652	LysM domain
HEC95_RS18235	COG0401	homolog of Blt101
HEC95_RS18255	COG0640	Transcriptional regulator
HEC95_RS18260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEC95_RS18285	COG4575	ribosome binding
HEC95_RS18295	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEC95_RS18335	COG2814	Major facilitator Superfamily
HEC95_RS18340	COG1846	Transcriptional regulator
HEC95_RS18345	COG1566	PFAM secretion protein HlyD family protein
HEC95_RS18350	COG2814	Major facilitator Superfamily
HEC95_RS18370	COG1238	metal cluster binding
HEC95_RS18375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HEC95_RS18400	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HEC95_RS18420	COG1546	Belongs to the CinA family
HEC95_RS18425	COG2951	lytic endotransglycosylase activity
HEC95_RS18430	COG3730	PTS system glucitol sorbitol-specific
HEC95_RS18435	COG3732	PTS system glucitol sorbitol-specific
HEC95_RS18445	COG1028	Short-chain dehydrogenase reductase Sdr
HEC95_RS18450	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS18455	COG1349	DNA-binding transcription factor activity
HEC95_RS18460	COG0517	IMP dehydrogenase activity
HEC95_RS18460	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HEC95_RS18480	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HEC95_RS18485	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HEC95_RS18495	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEC95_RS18505	COG3260	NADH ubiquinone oxidoreductase 20
HEC95_RS18510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HEC95_RS18515	COG3261	NADH dehydrogenase
HEC95_RS18515	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HEC95_RS18520	COG0650	Formate hydrogenlyase subunit 4
HEC95_RS18525	COG0651	ATP synthesis coupled electron transport
HEC95_RS18530	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HEC95_RS18545	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HEC95_RS18550	COG0298	carbon dioxide binding
HEC95_RS18555	COG0409	Hydrogenase expression formation protein
HEC95_RS18560	COG0309	Hydrogenase expression formation protein (HypE)
HEC95_RS18580	COG1121	(ABC) transporter
HEC95_RS18585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HEC95_RS18590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HEC95_RS18675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEC95_RS18765	COG2207	Transcriptional regulator
HEC95_RS18830	COG0477	Major facilitator Superfamily
HEC95_RS18840	COG2610	gluconate transmembrane transporter activity
HEC95_RS18845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HEC95_RS18850	COG3622	Belongs to the hyi family
HEC95_RS18855	COG0235	Class ii aldolase
HEC95_RS18865	COG2084	Dehydrogenase
HEC95_RS18870	COG1349	DNA-binding transcription factor activity
HEC95_RS18880	COG0163	prenyltransferase activity
HEC95_RS18885	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HEC95_RS18955	COG2234	aminopeptidase activity
HEC95_RS18960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HEC95_RS18965	COG1518	maintenance of DNA repeat elements
HEC95_RS18980	COG1857	crispr-associated protein
HEC95_RS18995	COG1203	CRISPR-associated helicase, Cas3
HEC95_RS19020	COG0720	synthase
HEC95_RS19025	COG0321	lipoyl(octanoyl) transferase activity
HEC95_RS19025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HEC95_RS19030	COG0602	queuosine metabolic process
HEC95_RS19045	COG3956	TIGRFAM MazG family protein
HEC95_RS19050	COG3539	Fimbrial protein
HEC95_RS19055	COG3188	usher protein
HEC95_RS19060	COG3121	Chaperone
HEC95_RS19065	COG3539	Fimbrial protein
HEC95_RS19085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEC95_RS19095	COG4999	Histidine kinase
HEC95_RS19095	COG3437	response regulator, receiver
HEC95_RS19095	COG2205	protein histidine kinase activity
HEC95_RS19095	COG3850	Histidine kinase
HEC95_RS19100	COG1929	Belongs to the glycerate kinase type-1 family
HEC95_RS19105	COG4948	Mandelate Racemase Muconate Lactonizing
HEC95_RS19110	COG4948	Mandelate Racemase Muconate Lactonizing
HEC95_RS19115	COG2271	Major facilitator Superfamily
HEC95_RS19125	COG0716	FMN binding
HEC95_RS19135	COG3098	single-species biofilm formation
HEC95_RS19155	COG1611	Belongs to the LOG family
HEC95_RS19160	COG0814	amino acid
HEC95_RS19165	COG1760	l-serine dehydratase
HEC95_RS19175	COG1454	alcohol dehydrogenase
HEC95_RS19180	COG0235	Class ii aldolase
HEC95_RS19185	COG0738	Major facilitator superfamily
HEC95_RS19205	COG1349	DNA-binding transcription factor activity
HEC95_RS19215	COG2363	Small membrane protein
HEC95_RS19220	COG0583	DNA-binding transcription factor activity
HEC95_RS19230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEC95_RS19235	COG2166	iron-sulfur cluster assembly
HEC95_RS19240	COG2962	Rard protein
HEC95_RS19245	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HEC95_RS19250	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HEC95_RS19265	COG0860	N-Acetylmuramoyl-L-alanine amidase
HEC95_RS19275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HEC95_RS19280	COG1074	ATP-dependent DNA helicase activity
HEC95_RS19285	COG1025	Belongs to the peptidase M16 family
HEC95_RS19290	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HEC95_RS19295	COG4967	type IV pilus modification protein PilV
HEC95_RS19305	COG4795	General secretion pathway protein
HEC95_RS19310	COG2165	general secretion pathway protein
HEC95_RS19340	COG0861	Integral membrane protein TerC family
HEC95_RS19350	COG0667	Aldo Keto reductase
HEC95_RS19370	COG1609	Transcriptional regulator
HEC95_RS19380	COG0583	DNA-binding transcription factor activity
HEC95_RS19385	COG1794	racemase activity, acting on amino acids and derivatives
HEC95_RS19390	COG2814	Major facilitator Superfamily
HEC95_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
HEC95_RS19405	COG0183	Belongs to the thiolase family
HEC95_RS19420	COG0814	amino acid
HEC95_RS19455	COG3188	usher protein
HEC95_RS19500	COG4942	peptidase
HEC95_RS19555	COG1272	protein, Hemolysin III
HEC95_RS19565	COG2723	6-phospho-beta-galactosidase activity
HEC95_RS19590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HEC95_RS19595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HEC95_RS19600	COG0006	proline dipeptidase activity
HEC95_RS19620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEC95_RS19625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HEC95_RS19640	COG2968	Membrane
HEC95_RS19650	COG0668	transmembrane transport
HEC95_RS19655	COG0191	fructose-bisphosphate aldolase activity
HEC95_RS19685	COG1122	ATPase activity
HEC95_RS19690	COG1122	ATPase activity
HEC95_RS19695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEC95_RS19700	COG0501	Belongs to the peptidase M48B family
HEC95_RS19715	COG2731	YhcH YjgK YiaL family protein
HEC95_RS19720	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HEC95_RS19725	COG1063	alcohol dehydrogenase
HEC95_RS19730	COG0246	Mannitol dehydrogenase
HEC95_RS19740	COG2186	Transcriptional regulator
HEC95_RS19750	COG1166	arginine decarboxylase activity
HEC95_RS19775	COG2814	Major facilitator Superfamily
HEC95_RS19785	COG2356	endonuclease I
HEC95_RS19790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HEC95_RS19815	COG2805	Type II/IV secretion system protein
HEC95_RS19820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEC95_RS19825	COG0762	integral membrane protein
HEC95_RS19840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HEC95_RS19850	COG0252	asparaginase activity
HEC95_RS19860	COG3171	Protein conserved in bacteria
HEC95_RS19890	COG1982	Orn Lys Arg decarboxylase major
HEC95_RS19895	COG1811	Na channel or pump
HEC95_RS19910	COG0427	acetyl-CoA hydrolase
HEC95_RS19915	COG2030	dehydratase
HEC95_RS19920	COG2301	Belongs to the HpcH HpaI aldolase family
HEC95_RS19950	COG0531	amino acid
HEC95_RS19960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HEC95_RS19965	COG1012	belongs to the aldehyde dehydrogenase family
HEC95_RS19990	COG2271	Major facilitator Superfamily
HEC95_RS20000	COG0246	Mannitol dehydrogenase
HEC95_RS20015	COG0754	glutathionylspermidine amidase activity
HEC95_RS20020	COG0625	glutathione transferase activity
HEC95_RS20035	COG0298	carbon dioxide binding
HEC95_RS20045	COG1773	rubredoxin
HEC95_RS20050	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEC95_RS20055	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HEC95_RS20060	COG5557	Pfam Polysulphide reductase, NrfD
HEC95_RS20065	COG0437	4 iron, 4 sulfur cluster binding
HEC95_RS20070	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HEC95_RS20080	COG0840	transmembrane signaling receptor activity
HEC95_RS20105	COG1028	Short-chain dehydrogenase reductase Sdr
HEC95_RS20110	COG0848	biopolymer transport protein
HEC95_RS20130	COG2207	Transcriptional regulator
HEC95_RS20135	COG1979	alcohol dehydrogenase
HEC95_RS20145	COG0471	metal ion transport
HEC95_RS20195	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HEC95_RS20200	COG3111	PFAM Bacterial OB fold (BOF) protein
HEC95_RS20215	COG2249	NAD(P)H dehydrogenase (quinone) activity
HEC95_RS20220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HEC95_RS20230	COG3150	esterase
HEC95_RS20235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HEC95_RS20240	COG3151	Protein conserved in bacteria
HEC95_RS20245	COG0494	nUDIX hydrolase
HEC95_RS20260	COG0754	glutathionylspermidine amidase activity
HEC95_RS20265	COG3384	dioxygenase
HEC95_RS20310	COG1585	Membrane protein implicated in regulation of membrane protease activity
HEC95_RS20315	COG2268	Band 7 protein
HEC95_RS20335	COG3025	triphosphatase activity
HEC95_RS20340	COG4991	sh3 domain protein
HEC95_RS20355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEC95_RS20380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HEC95_RS20405	COG2375	cellular response to nickel ion
HEC95_RS20410	COG1695	Transcriptional regulator
HEC95_RS20415	COG0840	transmembrane signaling receptor activity
HEC95_RS20420	COG0840	transmembrane signaling receptor activity
HEC95_RS20430	COG1902	pentaerythritol trinitrate reductase activity
HEC95_RS20430	COG0446	pyridine nucleotide-disulphide oxidoreductase
HEC95_RS20440	COG1451	nucleotide metabolic process
HEC95_RS20445	COG2949	membrane
HEC95_RS20450	COG0673	inositol 2-dehydrogenase activity
HEC95_RS20465	COG0586	Pfam SNARE associated Golgi protein
HEC95_RS20475	COG1422	Protein of unknown function (DUF1090)
HEC95_RS20480	COG4575	ribosome binding
HEC95_RS20485	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HEC95_RS20495	COG2259	Doxx family
HEC95_RS20500	COG0435	Glutathione S-transferase
HEC95_RS20505	COG3152	Membrane
HEC95_RS20510	COG0583	DNA-binding transcription factor activity
HEC95_RS20515	COG1741	Belongs to the pirin family
HEC95_RS20530	COG0814	amino acid
HEC95_RS20535	COG1760	l-serine dehydratase
HEC95_RS20540	COG1882	Formate acetyltransferase
HEC95_RS20560	COG0583	DNA-binding transcription factor activity
HEC95_RS20570	COG1929	Belongs to the glycerate kinase type-1 family
HEC95_RS20575	COG2084	Dehydrogenase
HEC95_RS20585	COG2721	sulfolactate sulfo-lyase activity
HEC95_RS20600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS20605	COG3414	Phosphotransferase system galactitol-specific IIB component
HEC95_RS20610	COG3775	system Galactitol-specific IIC component
HEC95_RS20615	COG1063	alcohol dehydrogenase
HEC95_RS20625	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEC95_RS20630	COG3107	peptidoglycan biosynthetic process
HEC95_RS20645	COG2823	Periplasmic or secreted lipoprotein
HEC95_RS20650	COG0702	epimerase
HEC95_RS20655	COG0693	protein deglycase activity
HEC95_RS20670	COG3153	acetyltransferase
HEC95_RS20675	COG3154	lipid carrier protein
HEC95_RS20680	COG0826	peptidase U32
HEC95_RS20685	COG0826	peptidase U32
HEC95_RS20690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEC95_RS20695	COG3034	peptidoglycan biosynthetic process
HEC95_RS20705	COG0814	amino acid
HEC95_RS20710	COG0513	Belongs to the DEAD box helicase family
HEC95_RS20780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HEC95_RS20790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEC95_RS20805	COG1534	Rna-binding protein
HEC95_RS20815	COG2027	D-alanyl-D-alanine carboxypeptidase
HEC95_RS20825	COG0697	spore germination
HEC95_RS20840	COG0142	geranyltranstransferase activity
HEC95_RS20845	COG3423	Transcriptional regulator
HEC95_RS20855	COG5007	Belongs to the BolA IbaG family
HEC95_RS20860	COG3113	response to antibiotic
HEC95_RS20865	COG2854	intermembrane phospholipid transfer
HEC95_RS20870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HEC95_RS20875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HEC95_RS20880	COG1127	ABC transporter
HEC95_RS20885	COG0530	calcium, potassium:sodium antiporter activity
HEC95_RS20895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HEC95_RS20900	COG3117	lipopolysaccharide transmembrane transporter activity
HEC95_RS20905	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HEC95_RS20910	COG1137	ATPase activity
HEC95_RS20935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS20940	COG0515	serine threonine protein kinase
HEC95_RS20950	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HEC95_RS20955	COG0784	Response regulator, receiver
HEC95_RS20955	COG5002	protein histidine kinase activity
HEC95_RS20955	COG2198	Histidine kinase
HEC95_RS20960	COG1242	4 iron, 4 sulfur cluster binding
HEC95_RS20965	COG0067	glutamate synthase
HEC95_RS20965	COG0069	glutamate synthase activity
HEC95_RS20965	COG0070	glutamate synthase
HEC95_RS20970	COG0493	'glutamate synthase
HEC95_RS20975	COG4804	nuclease activity
HEC95_RS20980	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HEC95_RS20985	COG0402	S-adenosylhomocysteine deaminase activity
HEC95_RS20990	COG2731	YhcH YjgK YiaL family protein
HEC95_RS21020	COG2969	positive regulation of protein catabolic process
HEC95_RS21025	COG0625	glutathione transferase activity
HEC95_RS21045	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HEC95_RS21050	COG3105	Protein conserved in bacteria
HEC95_RS21055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEC95_RS21065	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HEC95_RS21070	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HEC95_RS21075	COG0511	ligase activity, forming carbon-carbon bonds
HEC95_RS21075	COG5016	pyruvate
HEC95_RS21085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HEC95_RS21090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HEC95_RS21095	COG0471	metal ion transport
HEC95_RS21105	COG2188	Transcriptional regulator
HEC95_RS21130	COG2732	(Barnase) inhibitor
HEC95_RS21150	COG0583	DNA-binding transcription factor activity
HEC95_RS21155	COG0312	modulator of DNA gyrase
HEC95_RS21160	COG3164	Protein of unknown function
HEC95_RS21165	COG1530	ribonuclease E activity
HEC95_RS21175	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HEC95_RS21180	COG1792	Involved in formation and maintenance of cell shape
HEC95_RS21185	COG1077	Cell shape determining protein MreB Mrl
HEC95_RS21190	COG2199	diguanylate cyclase activity
HEC95_RS21190	COG2200	EAL domain
HEC95_RS21195	COG0604	alcohol dehydrogenase
HEC95_RS21210	COG0511	ligase activity, forming carbon-carbon bonds
HEC95_RS21215	COG0439	Biotin carboxylase
HEC95_RS21220	COG3924	membrane
HEC95_RS21225	COG4145	pantothenate transmembrane transporter activity
HEC95_RS21245	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HEC95_RS21260	COG1309	transcriptional regulator
HEC95_RS21265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEC95_RS21270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEC95_RS21380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HEC95_RS21385	COG2104	thiamine diphosphate biosynthetic process
HEC95_RS21450	COG0250	Participates in transcription elongation, termination and antitermination
HEC95_RS21560	COG0583	DNA-binding transcription factor activity
HEC95_RS21595	COG2207	Transcriptional regulator
HEC95_RS21600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEC95_RS21605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEC95_RS21610	COG1882	Formate acetyltransferase
HEC95_RS21615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEC95_RS21620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEC95_RS21625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEC95_RS21625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS21625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEC95_RS21635	COG0371	Dehydrogenase
HEC95_RS21640	COG3738	Protein conserved in bacteria
HEC95_RS21660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEC95_RS21665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEC95_RS21670	COG0737	Belongs to the 5'-nucleotidase family
HEC95_RS21685	COG0668	transmembrane transport
HEC95_RS21690	COG0527	aspartate kinase activity
HEC95_RS21690	COG0460	homoserine dehydrogenase
HEC95_RS21695	COG0626	cystathionine gamma-synthase activity
HEC95_RS21720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEC95_RS21725	COG1609	Transcriptional regulator
HEC95_RS21730	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEC95_RS21745	COG1575	Belongs to the MenA family. Type 1 subfamily
HEC95_RS21760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HEC95_RS21770	COG1494	fructose-1,6-bisphosphatase
HEC95_RS21780	COG3152	Membrane
HEC95_RS21810	COG1879	ABC-type sugar transport system periplasmic component
HEC95_RS21835	COG1070	Carbohydrate kinase
HEC95_RS21845	COG2134	cdp-diacylglycerol pyrophosphatase
HEC95_RS21855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEC95_RS21865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS21870	COG2211	Major facilitator Superfamily
HEC95_RS21895	COG3678	ATP-independent chaperone mediated protein folding
HEC95_RS21900	COG0745	RESPONSE REGULATOR receiver
HEC95_RS21905	COG2205	protein histidine kinase activity
HEC95_RS21920	COG2258	MOSC domain
HEC95_RS21925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEC95_RS21970	COG1454	alcohol dehydrogenase
HEC95_RS21985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HEC95_RS22015	COG0437	4 iron, 4 sulfur cluster binding
HEC95_RS22020	COG2864	formate dehydrogenase
HEC95_RS22035	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HEC95_RS22045	COG4680	protein conserved in bacteria
HEC95_RS22050	COG5499	transcription regulator containing HTH domain
HEC95_RS22055	COG0456	acetyltransferase
HEC95_RS22070	COG1011	Hydrolase
HEC95_RS22075	COG1349	DNA-binding transcription factor activity
HEC95_RS22080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS22090	COG3684	Belongs to the aldolase LacD family
HEC95_RS22100	COG2017	converts alpha-aldose to the beta-anomer
HEC95_RS22105	COG1501	Belongs to the glycosyl hydrolase 31 family
HEC95_RS22150	COG0561	phosphatase activity
HEC95_RS22205	COG0204	Acyl-transferase
HEC95_RS22220	COG3084	Protein conserved in bacteria
HEC95_RS22230	COG1763	Mo-molybdopterin cofactor biosynthetic process
HEC95_RS22270	COG1739	Uncharacterized protein family UPF0029
HEC95_RS22300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HEC95_RS22315	COG0805	protein transport
HEC95_RS22360	COG0641	radical SAM
HEC95_RS22380	COG0561	phosphatase activity
HEC95_RS22385	COG2267	carboxylic ester hydrolase activity
HEC95_RS22440	COG1011	Hydrolase
HEC95_RS22500	COG2959	enzyme of heme biosynthesis
HEC95_RS22505	COG3071	HemY protein
HEC95_RS22550	COG2244	polysaccharide biosynthetic process
HEC95_RS22555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEC95_RS22560	COG0456	acetyltransferase
HEC95_RS22565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEC95_RS22565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEC95_RS22570	COG1088	dTDP-glucose 4,6-dehydratase activity
HEC95_RS22575	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HEC95_RS22605	COG3118	belongs to the thioredoxin family
HEC95_RS22670	COG3978	acetolactate synthase activity
HEC95_RS22730	COG2186	Transcriptional regulator
HEC95_RS22735	COG0477	Major facilitator Superfamily
HEC95_RS22740	COG0477	Major facilitator Superfamily
HEC95_RS22745	COG1609	Transcriptional regulator
HEC95_RS22750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEC95_RS22760	COG1172	Belongs to the binding-protein-dependent transport system permease family
HEC95_RS22795	COG1522	sequence-specific DNA binding
HEC95_RS22800	COG0716	FMN binding
HEC95_RS22815	COG3312	ion transport
HEC95_RS22875	COG4533	DNA binding
HEC95_RS22880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEC95_RS22885	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HEC95_RS22885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEC95_RS22885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HEC95_RS22890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HEC95_RS22895	COG0573	inorganic phosphate transmembrane transporter activity
HEC95_RS22900	COG0581	inorganic phosphate transmembrane transporter activity
HEC95_RS22910	COG0704	Plays a role in the regulation of phosphate uptake
HEC95_RS22915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HEC95_RS22920	COG2252	PERMEase
HEC95_RS22925	COG0431	NADPH-dependent FMN reductase
HEC95_RS22930	COG2091	lysine biosynthetic process via aminoadipic acid
HEC95_RS22980	COG3111	PFAM Bacterial OB fold (BOF) protein
HEC95_RS23040	COG3204	pilus organization
HEC95_RS23050	COG2207	Transcriptional regulator
HEC95_RS23055	COG3204	pilus organization
HEC95_RS23235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HEC95_RS23300	COG4932	domain protein
HEC95_RS23300	COG2373	Large extracellular alpha-helical protein
HEC95_RS23300	COG1388	LysM domain