locus-tag	class	description
APS45_RS00010	COG0527	aspartate kinase activity
APS45_RS00010	COG0460	homoserine dehydrogenase
APS45_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
APS45_RS00030	COG1115	amino acid carrier protein
APS45_RS00040	COG0521	Mo-molybdopterin cofactor biosynthetic process
APS45_RS00045	COG1584	GPR1 FUN34 yaaH family protein
APS45_RS00050	COG4735	regulation of single-species biofilm formation
APS45_RS00110	COG3121	Chaperone
APS45_RS00115	COG3188	usher protein
APS45_RS00130	COG3539	Fimbrial protein
APS45_RS00135	COG3121	Chaperone
APS45_RS00170	COG3119	arylsulfatase activity
APS45_RS00175	COG0641	radical SAM
APS45_RS00195	COG0583	DNA-binding transcription factor activity
APS45_RS00220	COG0196	riboflavin kinase activity
APS45_RS00235	COG1047	Peptidyl-prolyl cis-trans
APS45_RS00325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
APS45_RS00380	COG0644	oxidoreductase
APS45_RS00390	COG2271	Major facilitator Superfamily
APS45_RS00415	COG3119	arylsulfatase activity
APS45_RS00480	COG0417	DNA replication proofreading
APS45_RS00515	COG0586	Pfam SNARE associated Golgi protein
APS45_RS00605	COG0768	penicillin binding
APS45_RS00610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APS45_RS00615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
APS45_RS00630	COG0772	Belongs to the SEDS family
APS45_RS00655	COG0849	cell division
APS45_RS00660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APS45_RS00680	COG0494	nUDIX hydrolase
APS45_RS00710	COG1459	type II secretion system
APS45_RS00715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APS45_RS00720	COG4969	Belongs to the N-Me-Phe pilin family
APS45_RS00735	COG3725	Membrane protein required for beta-lactamase induction
APS45_RS00740	COG3940	Belongs to the glycosyl hydrolase 43 family
APS45_RS00745	COG2211	Major facilitator Superfamily
APS45_RS00760	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
APS45_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
APS45_RS00770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
APS45_RS00785	COG3064	Membrane
APS45_RS00855	COG1349	DNA-binding transcription factor activity
APS45_RS00875	COG2132	Multicopper oxidase
APS45_RS00880	COG4993	Dehydrogenase
APS45_RS00890	COG0288	reversible hydration of carbon dioxide
APS45_RS00895	COG1131	(ABC) transporter
APS45_RS00900	COG0842	Transport permease protein
APS45_RS00905	COG3539	Fimbrial protein
APS45_RS00925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS00930	COG0726	polysaccharide deacetylase
APS45_RS00950	COG3539	Fimbrial protein
APS45_RS00955	COG3188	usher protein
APS45_RS00960	COG3121	Chaperone
APS45_RS00985	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APS45_RS01010	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
APS45_RS01015	COG1643	Atp-dependent helicase
APS45_RS01020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
APS45_RS01025	COG4774	siderophore transport
APS45_RS01030	COG1120	ATPase activity
APS45_RS01035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
APS45_RS01050	COG3188	usher protein
APS45_RS01055	COG3121	Chaperone
APS45_RS01060	COG3539	Fimbrial protein
APS45_RS01065	COG3539	Fimbrial protein
APS45_RS01095	COG2860	membrane
APS45_RS01120	COG3835	regulator
APS45_RS01130	COG0477	Major facilitator Superfamily
APS45_RS01180	COG0575	Belongs to the CDS family
APS45_RS01240	COG1982	Orn Lys Arg decarboxylase major
APS45_RS01245	COG0346	lactoylglutathione lyase activity
APS45_RS01255	COG4568	rho-dependent transcription termination
APS45_RS01270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APS45_RS01275	COG3015	lipoprotein NlpE involved in copper resistance
APS45_RS01285	COG1720	tRNA m6t6A37 methyltransferase activity
APS45_RS01310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
APS45_RS01350	COG0583	DNA-binding transcription factor activity
APS45_RS01355	COG2814	Major facilitator Superfamily
APS45_RS01365	COG2226	methyltransferase
APS45_RS01370	COG1388	LysM domain
APS45_RS01370	COG0741	lytic transglycosylase activity
APS45_RS01380	COG2226	methyltransferase
APS45_RS01490	COG3047	cAMP biosynthetic process
APS45_RS01490	COG2885	chlorophyll binding
APS45_RS01545	COG3209	COG3209 Rhs family protein
APS45_RS01600	COG1522	sequence-specific DNA binding
APS45_RS01625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
APS45_RS01640	COG0121	glutamine amidotransferase
APS45_RS01645	COG3034	peptidoglycan biosynthetic process
APS45_RS01655	COG1690	Belongs to the RtcB family
APS45_RS01660	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APS45_RS01665	COG2195	Cleaves the N-terminal amino acid of tripeptides
APS45_RS01705	COG0582	viral genome integration into host DNA
APS45_RS01815	COG0305	Participates in initiation and elongation during chromosome replication
APS45_RS01850	COG0484	heat shock protein binding
APS45_RS01860	COG3772	lysozyme
APS45_RS01975	COG0463	Glycosyl transferase, family 2
APS45_RS01980	COG2246	polysaccharide biosynthetic process
APS45_RS02000	COG2814	Major facilitator Superfamily
APS45_RS02015	COG0179	Fumarylacetoacetate (FAA) hydrolase
APS45_RS02050	COG3188	usher protein
APS45_RS02055	COG3121	Chaperone
APS45_RS02060	COG3539	Fimbrial protein
APS45_RS02075	COG2200	EAL domain
APS45_RS02130	COG0789	Transcriptional regulator
APS45_RS02145	COG2814	Major facilitator Superfamily
APS45_RS02165	COG1271	oxidase subunit
APS45_RS02170	COG1294	oxidase, subunit
APS45_RS02190	COG1280	lysine exporter protein (LysE YggA)
APS45_RS02215	COG2079	MmgE PrpD family protein
APS45_RS02225	COG0113	porphobilinogen synthase activity
APS45_RS02240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
APS45_RS02245	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
APS45_RS02290	COG3706	GGDEF domain
APS45_RS02295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APS45_RS02315	COG4126	flavin adenine dinucleotide binding
APS45_RS02330	COG1940	carbohydrate kinase activity
APS45_RS02335	COG2814	Major facilitator Superfamily
APS45_RS02340	COG0419	ATPase involved in DNA repair
APS45_RS02345	COG0420	3'-5' exonuclease activity
APS45_RS02360	COG5002	protein histidine kinase activity
APS45_RS02375	COG0366	Alpha amylase catalytic
APS45_RS02380	COG0450	alkyl hydroperoxide reductase
APS45_RS02400	COG1862	Preprotein translocase
APS45_RS02410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APS45_RS02440	COG4238	major outer membrane lipoprotein
APS45_RS02450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APS45_RS02450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APS45_RS02465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
APS45_RS02470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
APS45_RS02475	COG0667	Aldo Keto reductase
APS45_RS02485	COG0142	geranyltranstransferase activity
APS45_RS02520	COG2188	Transcriptional regulator
APS45_RS02550	COG2814	Major facilitator Superfamily
APS45_RS02570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
APS45_RS02575	COG1845	cytochrome c oxidase, subunit III
APS45_RS02580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APS45_RS02585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
APS45_RS02590	COG2223	nitrite transmembrane transporter activity
APS45_RS02595	COG3056	Lipoprotein
APS45_RS02600	COG0271	Belongs to the BolA IbaG family
APS45_RS02620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
APS45_RS02630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
APS45_RS02635	COG1555	photosystem II stabilization
APS45_RS02640	COG0824	Thioesterase
APS45_RS02650	COG4533	DNA binding
APS45_RS02665	COG1522	sequence-specific DNA binding
APS45_RS02670	COG1132	(ABC) transporter
APS45_RS02675	COG1132	(ABC) transporter
APS45_RS02680	COG0347	Belongs to the P(II) protein family
APS45_RS02685	COG0004	ammonium transporteR
APS45_RS02690	COG1946	Acyl-CoA thioesterase
APS45_RS02695	COG3126	Type III secretion system lipoprotein chaperone (YscW)
APS45_RS02700	COG3695	enzyme binding
APS45_RS02710	COG4943	cyclic-guanylate-specific phosphodiesterase activity
APS45_RS02730	COG0110	maltose O-acetyltransferase activity
APS45_RS02745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APS45_RS02750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APS45_RS02755	COG1309	transcriptional regulator
APS45_RS02760	COG1196	nuclear chromosome segregation
APS45_RS02760	COG3264	Mechanosensitive ion channel
APS45_RS02765	COG5464	transposase or invertase
APS45_RS02770	COG5464	transposase or invertase
APS45_RS02780	COG3923	Primosomal replication protein n
APS45_RS02785	COG2832	Protein of unknown function (DUF454)
APS45_RS02830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APS45_RS02835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
APS45_RS02835	COG4651	solute:proton antiporter activity
APS45_RS02840	COG2223	nitrite transmembrane transporter activity
APS45_RS02855	COG3735	TraB family
APS45_RS02875	COG1585	Membrane protein implicated in regulation of membrane protease activity
APS45_RS02880	COG0330	HflC and HflK could
APS45_RS02885	COG4619	ABC transporter
APS45_RS02890	COG0390	transport system, permease component
APS45_RS02895	COG3118	belongs to the thioredoxin family
APS45_RS02900	COG0300	oxidoreductase activity
APS45_RS02905	COG2755	lipolytic protein G-D-S-L family
APS45_RS02910	COG4181	ATPase activity
APS45_RS02915	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
APS45_RS02925	COG1464	Belongs to the NlpA lipoprotein family
APS45_RS02960	COG3960	tartronate-semialdehyde synthase activity
APS45_RS02965	COG3622	Belongs to the hyi family
APS45_RS02970	COG2084	Dehydrogenase
APS45_RS02990	COG2233	PERMEase
APS45_RS02995	COG1929	Belongs to the glycerate kinase type-1 family
APS45_RS03000	COG3257	ureidoglycine aminohydrolase activity
APS45_RS03005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
APS45_RS03010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
APS45_RS03015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
APS45_RS03020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
APS45_RS03030	COG0549	Belongs to the carbamate kinase family
APS45_RS03035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APS45_RS03040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APS45_RS03050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APS45_RS03070	COG1988	membrane-bound metal-dependent
APS45_RS03075	COG2501	S4 domain
APS45_RS03140	COG0582	viral genome integration into host DNA
APS45_RS03145	COG2963	transposase activity
APS45_RS03155	COG0463	Glycosyl transferase, family 2
APS45_RS03160	COG2246	polysaccharide biosynthetic process
APS45_RS03170	COG5002	protein histidine kinase activity
APS45_RS03175	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APS45_RS03180	COG2207	Transcriptional regulator
APS45_RS03185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
APS45_RS03195	COG3059	membrane
APS45_RS03205	COG1113	amino acid transport
APS45_RS03210	COG0668	transmembrane transport
APS45_RS03220	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
APS45_RS03220	COG3933	PFAM sigma-54 factor interaction domain-containing protein
APS45_RS03225	COG2222	sugar isomerase
APS45_RS03235	COG3716	PTS system mannose fructose sorbose family IID component
APS45_RS03260	COG2315	Protein conserved in bacteria
APS45_RS03285	COG2977	Belongs to the P-Pant transferase superfamily
APS45_RS03290	COG4771	TonB-dependent receptor
APS45_RS03295	COG2382	esterase
APS45_RS03300	COG3251	PFAM MbtH domain protein
APS45_RS03305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
APS45_RS03305	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
APS45_RS03310	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
APS45_RS03315	COG1120	ATPase activity
APS45_RS03320	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APS45_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APS45_RS03335	COG4592	Periplasmic binding protein
APS45_RS03340	COG1169	isochorismate synthase
APS45_RS03345	COG1021	2,3-dihydroxybenzoate-AMP ligase
APS45_RS03350	COG1535	isochorismatase
APS45_RS03350	COG3433	isochorismatase activity
APS45_RS03355	COG1028	Short-chain dehydrogenase reductase Sdr
APS45_RS03365	COG1966	Carbon starvation protein
APS45_RS03370	COG2879	small protein
APS45_RS03375	COG0371	Dehydrogenase
APS45_RS03380	COG0436	Aminotransferase
APS45_RS03385	COG1475	DNA binding
APS45_RS03390	COG3969	phosphoadenosine phosphosulfate
APS45_RS03395	COG0583	DNA-binding transcription factor activity
APS45_RS03400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
APS45_RS03420	COG0243	molybdopterin cofactor binding
APS45_RS03440	COG1063	alcohol dehydrogenase
APS45_RS03445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
APS45_RS03450	COG3719	Belongs to the RNase T2 family
APS45_RS03455	COG0471	metal ion transport
APS45_RS03470	COG3051	citrate lyase alpha subunit
APS45_RS03475	COG2301	Belongs to the HpcH HpaI aldolase family
APS45_RS03485	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
APS45_RS03490	COG3290	protein histidine kinase activity
APS45_RS03495	COG4565	transcriptional regulatory protein
APS45_RS03500	COG3069	C4-dicarboxylate transmembrane transporter activity
APS45_RS03520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
APS45_RS03535	COG0583	DNA-binding transcription factor activity
APS45_RS03550	COG1686	Belongs to the peptidase S11 family
APS45_RS03560	COG0772	Belongs to the SEDS family
APS45_RS03565	COG0768	penicillin binding
APS45_RS03575	COG0799	negative regulation of ribosome biogenesis
APS45_RS03600	COG1466	dna polymerase III delta subunit
APS45_RS03630	COG3829	transcription factor binding
APS45_RS03630	COG3290	protein histidine kinase activity
APS45_RS03635	COG2888	peptidyl-tyrosine sulfation
APS45_RS03650	COG2214	Heat shock protein DnaJ domain protein
APS45_RS03660	COG2214	Heat shock protein DnaJ domain protein
APS45_RS03665	COG0443	Heat shock 70 kDa protein
APS45_RS03680	COG1126	abc transporter atp-binding protein
APS45_RS03685	COG0765	amino acid transport
APS45_RS03690	COG0765	amino acid transport
APS45_RS03715	COG1702	phosphate starvation-inducible protein PhoH
APS45_RS03725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
APS45_RS03770	COG0367	asparagine synthase
APS45_RS03775	COG0647	UMP catabolic process
APS45_RS03780	COG1940	carbohydrate kinase activity
APS45_RS03780	COG1846	Transcriptional regulator
APS45_RS03785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APS45_RS03825	COG1053	succinate dehydrogenase
APS45_RS03830	COG0583	DNA-binding transcription factor activity
APS45_RS03835	COG0735	belongs to the Fur family
APS45_RS03850	COG0596	Alpha beta hydrolase
APS45_RS03860	COG0033	Phosphoglucomutase
APS45_RS03870	COG0531	amino acid
APS45_RS03875	COG1982	Orn Lys Arg decarboxylase major
APS45_RS03885	COG0745	RESPONSE REGULATOR receiver
APS45_RS03890	COG2205	protein histidine kinase activity
APS45_RS03935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
APS45_RS03940	COG1984	allophanate hydrolase subunit 2
APS45_RS03955	COG0582	viral genome integration into host DNA
APS45_RS03995	COG1216	Glycosyl transferase, family 2
APS45_RS04020	COG3180	Ammonia monooxygenase
APS45_RS04040	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
APS45_RS04055	COG0567	Dehydrogenase, E1 component
APS45_RS04060	COG0508	dehydrogenase complex catalyzes the overall conversion of
APS45_RS04070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
APS45_RS04080	COG1271	oxidase subunit
APS45_RS04085	COG1294	oxidase, subunit
APS45_RS04090	COG4890	Cyd operon protein YbgT
APS45_RS04095	COG3790	cyd operon protein YbgE
APS45_RS04100	COG0824	Thioesterase
APS45_RS04105	COG0811	peptide transport
APS45_RS04110	COG0848	biopolymer transport protein
APS45_RS04115	COG3064	Membrane
APS45_RS04125	COG2885	chlorophyll binding
APS45_RS04130	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
APS45_RS04195	COG1230	cation diffusion facilitator family transporter
APS45_RS04205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
APS45_RS04210	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
APS45_RS04210	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
APS45_RS04220	COG0583	DNA-binding transcription factor activity
APS45_RS04225	COG0583	DNA-binding transcription factor activity
APS45_RS04230	COG0471	metal ion transport
APS45_RS04230	COG0490	domain, Protein
APS45_RS04245	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
APS45_RS04255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APS45_RS04260	COG1120	ATPase activity
APS45_RS04270	COG2017	converts alpha-aldose to the beta-anomer
APS45_RS04295	COG1119	ATPase activity
APS45_RS04300	COG3585	molybdate ion transport
APS45_RS04300	COG2005	Transcriptional regulator
APS45_RS04310	COG0725	ABC transporter, periplasmic molybdate-binding protein
APS45_RS04315	COG4149	molybdate abc transporter
APS45_RS04325	COG0561	phosphatase activity
APS45_RS04335	COG4677	pectinesterase activity
APS45_RS04365	COG1881	PFAM PEBP family protein
APS45_RS04420	COG0521	Mo-molybdopterin cofactor biosynthetic process
APS45_RS04430	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
APS45_RS04440	COG0670	Belongs to the BI1 family
APS45_RS04460	COG0392	lysyltransferase activity
APS45_RS04465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APS45_RS04470	COG3568	Endonuclease Exonuclease Phosphatase
APS45_RS04480	COG0842	Transport permease protein
APS45_RS04485	COG0842	Transport permease protein
APS45_RS04490	COG1131	(ABC) transporter
APS45_RS04500	COG1309	transcriptional regulator
APS45_RS04505	COG0513	Belongs to the DEAD box helicase family
APS45_RS04515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
APS45_RS04530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
APS45_RS04540	COG0668	transmembrane transport
APS45_RS04545	COG1126	abc transporter atp-binding protein
APS45_RS04550	COG0765	amino acid transport
APS45_RS04555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APS45_RS04570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
APS45_RS04575	COG2194	sulfuric ester hydrolase activity
APS45_RS04585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APS45_RS04590	COG1376	ErfK ybiS ycfS ynhG family protein
APS45_RS04595	COG0488	(ABC) transporter
APS45_RS04605	COG0561	phosphatase activity
APS45_RS04610	COG1882	Formate acetyltransferase
APS45_RS04615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APS45_RS04665	COG2301	Belongs to the HpcH HpaI aldolase family
APS45_RS04685	COG1960	acyl-CoA dehydrogenase activity
APS45_RS04695	COG0583	DNA-binding transcription factor activity
APS45_RS04700	COG2610	gluconate transmembrane transporter activity
APS45_RS04705	COG2133	pyrroloquinoline quinone binding
APS45_RS04710	COG2133	pyrroloquinoline quinone binding
APS45_RS04715	COG0625	glutathione transferase activity
APS45_RS04720	COG1686	Belongs to the peptidase S11 family
APS45_RS04725	COG1349	DNA-binding transcription factor activity
APS45_RS04730	COG0671	phosphoesterase, PA-phosphatase related
APS45_RS04735	COG2814	Major facilitator Superfamily
APS45_RS04740	COG0561	phosphatase activity
APS45_RS04745	COG0738	Major facilitator superfamily
APS45_RS04750	COG3226	Transcriptional regulator
APS45_RS04790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
APS45_RS04795	COG3842	ATPase activity
APS45_RS04800	COG1176	ABC-type spermidine putrescine transport system, permease component I
APS45_RS04805	COG1177	transmembrane transport
APS45_RS04835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APS45_RS04840	COG4160	amino acid transport
APS45_RS04845	COG4215	(ABC) transporter
APS45_RS04850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APS45_RS04855	COG1126	abc transporter atp-binding protein
APS45_RS04870	COG3023	N-Acetylmuramoyl-L-alanine amidase
APS45_RS04875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
APS45_RS04880	COG0702	epimerase
APS45_RS04885	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
APS45_RS04890	COG0028	Belongs to the TPP enzyme family
APS45_RS04895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APS45_RS04905	COG2431	L-lysine efflux transmembrane transporter activity
APS45_RS04910	COG3593	DNA synthesis involved in DNA repair
APS45_RS04915	COG2990	Protein conserved in bacteria
APS45_RS04920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APS45_RS04925	COG1136	(ABC) transporter
APS45_RS04925	COG0577	efflux transmembrane transporter activity
APS45_RS04930	COG1278	Cold shock
APS45_RS04940	COG0542	response to heat
APS45_RS04970	COG1335	isochorismatase
APS45_RS04980	COG0583	DNA-binding transcription factor activity
APS45_RS05000	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
APS45_RS05005	COG4988	ABC transporter
APS45_RS05010	COG0492	ferredoxin-NADP+ reductase activity
APS45_RS05030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
APS45_RS05040	COG0243	molybdopterin cofactor binding
APS45_RS05045	COG0437	4 iron, 4 sulfur cluster binding
APS45_RS05050	COG3302	dmso reductase anchor subunit
APS45_RS05065	COG0531	amino acid
APS45_RS05070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APS45_RS05080	COG1882	Formate acetyltransferase
APS45_RS05085	COG2116	formate transmembrane transporter activity
APS45_RS05090	COG1944	ATP diphosphatase activity
APS45_RS05095	COG2323	membrane
APS45_RS05110	COG0501	Belongs to the peptidase M48B family
APS45_RS05120	COG0539	negative regulation of cytoplasmic translation
APS45_RS05130	COG0658	competence protein
APS45_RS05130	COG2333	competence protein COMEC
APS45_RS05145	COG3214	Protein conserved in bacteria
APS45_RS05160	COG3173	Aminoglycoside phosphotransferase
APS45_RS05165	COG1434	Gram-negative-bacterium-type cell wall biogenesis
APS45_RS05170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
APS45_RS05180	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
APS45_RS05190	COG2989	Protein conserved in bacteria
APS45_RS05195	COG3108	Peptidase M15
APS45_RS05200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
APS45_RS05220	COG1522	sequence-specific DNA binding
APS45_RS05235	COG1115	amino acid carrier protein
APS45_RS05245	COG0582	viral genome integration into host DNA
APS45_RS05375	COG0484	heat shock protein binding
APS45_RS05400	COG3772	lysozyme
APS45_RS05515	COG5301	cellulose 1,4-beta-cellobiosidase activity
APS45_RS05535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
APS45_RS05545	COG0308	aminopeptidase N
APS45_RS05560	COG0633	Ferredoxin
APS45_RS05560	COG3217	Mosc domain protein beta barrel domain protein
APS45_RS05570	COG0488	(ABC) transporter
APS45_RS05575	COG2995	paraquat-inducible protein a
APS45_RS05580	COG3008	intermembrane lipid transfer
APS45_RS05580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
APS45_RS05585	COG3009	Protein conserved in bacteria
APS45_RS05590	COG3130	regulation of translation
APS45_RS05600	COG1067	ATP-dependent peptidase activity
APS45_RS05620	COG3070	regulator of competence-specific genes
APS45_RS05625	COG1289	transmembrane transporter activity
APS45_RS05630	COG3304	Inner membrane component domain
APS45_RS05635	COG0210	DNA helicase
APS45_RS05650	COG1832	CoA-binding protein
APS45_RS05665	COG1881	PFAM PEBP family protein
APS45_RS05685	COG0670	Belongs to the BI1 family
APS45_RS05735	COG2205	protein histidine kinase activity
APS45_RS05755	COG2368	4-hydroxyphenylacetate
APS45_RS05760	COG1846	Transcriptional regulator
APS45_RS05770	COG1012	belongs to the aldehyde dehydrogenase family
APS45_RS05775	COG3384	dioxygenase
APS45_RS05785	COG3971	2-oxopent-4-enoate hydratase activity
APS45_RS05830	COG4232	protein-disulfide reductase activity
APS45_RS05835	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
APS45_RS05835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
APS45_RS05840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
APS45_RS05860	COG3729	General stress protein
APS45_RS05865	COG1309	transcriptional regulator
APS45_RS05890	COG1702	phosphate starvation-inducible protein PhoH
APS45_RS05895	COG1737	Transcriptional regulator
APS45_RS05900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APS45_RS05920	COG2814	Major facilitator Superfamily
APS45_RS05925	COG0673	inositol 2-dehydrogenase activity
APS45_RS05960	COG3381	protein complex oligomerization
APS45_RS06015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APS45_RS06035	COG5645	(Lipo)protein
APS45_RS06050	COG1560	Kdo2-lipid A biosynthetic process
APS45_RS06065	COG3038	cytochrome b561
APS45_RS06100	COG2999	glutathione oxidoreductase activity
APS45_RS06110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APS45_RS06200	COG1530	ribonuclease E activity
APS45_RS06265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
APS45_RS06270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
APS45_RS06275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APS45_RS06285	COG0470	DNA polymerase III
APS45_RS06290	COG0084	hydrolase, TatD family'
APS45_RS06300	COG4773	Receptor
APS45_RS06305	COG0537	adenosine 5'-monophosphoramidase activity
APS45_RS06310	COG5633	Lipoprotein
APS45_RS06335	COG1252	NADH dehydrogenase
APS45_RS06340	COG3134	Outer membrane lipoprotein
APS45_RS06345	COG1309	transcriptional regulator
APS45_RS06355	COG1376	ErfK ybiS ycfS ynhG family protein
APS45_RS06355	COG1388	LysM domain
APS45_RS06360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APS45_RS06365	COG4591	ABC-type transport system involved in lipoprotein release permease component
APS45_RS06370	COG1136	(ABC) transporter
APS45_RS06375	COG4591	ABC-type transport system involved in lipoprotein release permease component
APS45_RS06395	COG1177	transmembrane transport
APS45_RS06425	COG2850	peptidyl-arginine hydroxylation
APS45_RS06440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APS45_RS06470	COG0538	isocitrate dehydrogenase activity
APS45_RS06565	COG0071	Belongs to the small heat shock protein (HSP20) family
APS45_RS06580	COG3038	cytochrome b561
APS45_RS06610	COG1124	(ABC) transporter
APS45_RS06615	COG0668	transmembrane transport
APS45_RS06630	COG3443	Belongs to the bacterial solute-binding protein 9 family
APS45_RS06645	COG0789	Transcriptional regulator
APS45_RS06660	COG1605	Chorismate mutase
APS45_RS06670	COG3615	Tellurite resistance protein tehB
APS45_RS06690	COG2261	transglycosylase associated protein
APS45_RS06695	COG3042	response to heat
APS45_RS06705	COG3189	MarR family transcriptional regulator
APS45_RS06710	COG2807	transmembrane transport
APS45_RS06715	COG2207	Transcriptional regulator
APS45_RS06730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APS45_RS06735	COG2199	diguanylate cyclase activity
APS45_RS06745	COG2766	serine protein kinase
APS45_RS06750	COG3713	MltA-interacting MipA family protein
APS45_RS06755	COG0641	radical SAM
APS45_RS06760	COG0656	L-ascorbic acid biosynthetic process
APS45_RS06780	COG3139	Protein of unknown function (DUF1315)
APS45_RS06785	COG1335	isochorismatase
APS45_RS06790	COG0252	asparaginase activity
APS45_RS06795	COG0616	signal peptide processing
APS45_RS06800	COG0778	Nitroreductase
APS45_RS06825	COG0494	nUDIX hydrolase
APS45_RS06860	COG3678	ATP-independent chaperone mediated protein folding
APS45_RS06865	COG0322	excinuclease ABC activity
APS45_RS06875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APS45_RS06880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APS45_RS06885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APS45_RS06890	COG1447	Phosphotransferase system cellobiose-specific component IIA
APS45_RS06895	COG1917	Cupin 2, conserved barrel domain protein
APS45_RS06895	COG2169	Transcriptional regulator
APS45_RS06900	COG1486	melibiose metabolic process
APS45_RS06910	COG0753	catalase activity
APS45_RS06920	COG1823	symporter activity
APS45_RS06925	COG1988	membrane-bound metal-dependent
APS45_RS06930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APS45_RS06940	COG3001	Fructosamine kinase
APS45_RS06950	COG1105	Belongs to the carbohydrate kinase PfkB family
APS45_RS06955	COG3137	Salt-induced outer membrane protein
APS45_RS07025	COG0386	Belongs to the glutathione peroxidase family
APS45_RS07035	COG0791	NLP P60 protein
APS45_RS07050	COG4256	Hemin uptake protein
APS45_RS07065	COG0574	Belongs to the PEP-utilizing enzyme family
APS45_RS07065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APS45_RS07070	COG0318	PFAM AMP-dependent synthetase and ligase
APS45_RS07075	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
APS45_RS07080	COG0644	oxidoreductase
APS45_RS07085	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
APS45_RS07090	COG2086	electron transfer activity
APS45_RS07095	COG1917	Cupin 2, conserved barrel domain protein
APS45_RS07095	COG2207	Transcriptional regulator
APS45_RS07100	COG1960	acyl-CoA dehydrogenase activity
APS45_RS07105	COG4670	ketone body catabolic process
APS45_RS07120	COG2271	Major facilitator Superfamily
APS45_RS07125	COG0738	Major facilitator superfamily
APS45_RS07140	COG0628	permease
APS45_RS07145	COG0247	lactate metabolic process
APS45_RS07145	COG0277	FAD linked oxidase domain protein
APS45_RS07150	COG2050	protein possibly involved in aromatic compounds catabolism
APS45_RS07160	COG1823	symporter activity
APS45_RS07165	COG0316	Belongs to the HesB IscA family
APS45_RS07170	COG0719	Fe-S assembly protein
APS45_RS07175	COG0396	ATPase activity
APS45_RS07180	COG0719	Fe-S assembly protein
APS45_RS07195	COG1376	ErfK ybiS ycfS ynhG family protein
APS45_RS07200	COG4238	major outer membrane lipoprotein
APS45_RS07220	COG0531	amino acid
APS45_RS07225	COG2267	carboxylic ester hydrolase activity
APS45_RS07235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APS45_RS07270	COG3272	Protein of unknown function (DUF1722)
APS45_RS07275	COG0789	Transcriptional regulator
APS45_RS07455	COG0307	riboflavin synthase, alpha
APS45_RS07460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
APS45_RS07465	COG2814	Major facilitator Superfamily
APS45_RS07470	COG0583	DNA-binding transcription factor activity
APS45_RS07485	COG0791	NLP P60 protein
APS45_RS07490	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
APS45_RS07505	COG1902	pentaerythritol trinitrate reductase activity
APS45_RS07510	COG1309	transcriptional regulator
APS45_RS07515	COG3313	Fe-S protein
APS45_RS07520	COG4989	oxidoreductase activity
APS45_RS07535	COG1566	PFAM secretion protein HlyD family protein
APS45_RS07560	COG3895	Periplasmic Protein
APS45_RS07580	COG0625	glutathione transferase activity
APS45_RS07590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APS45_RS07640	COG0673	inositol 2-dehydrogenase activity
APS45_RS07650	COG5339	Protein conserved in bacteria
APS45_RS07675	COG2205	protein histidine kinase activity
APS45_RS07680	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
APS45_RS07685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
APS45_RS07695	COG0745	RESPONSE REGULATOR receiver
APS45_RS07700	COG3136	membrane protein required for alginate biosynthesis
APS45_RS07705	COG0531	amino acid
APS45_RS07715	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
APS45_RS07720	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
APS45_RS07725	COG0628	permease
APS45_RS07740	COG3591	Belongs to the peptidase S1B family
APS45_RS07750	COG2814	Major facilitator Superfamily
APS45_RS07755	COG0583	DNA-binding transcription factor activity
APS45_RS07760	COG1940	carbohydrate kinase activity
APS45_RS07800	COG3302	dmso reductase anchor subunit
APS45_RS07805	COG0437	4 iron, 4 sulfur cluster binding
APS45_RS07810	COG0243	molybdopterin cofactor binding
APS45_RS07815	COG0243	molybdopterin cofactor binding
APS45_RS07830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APS45_RS07850	COG1063	alcohol dehydrogenase
APS45_RS07855	COG0477	Major facilitator Superfamily
APS45_RS07860	COG0246	Mannitol dehydrogenase
APS45_RS07870	COG1802	Transcriptional regulator
APS45_RS07875	COG4221	oxidoreductase activity
APS45_RS07885	COG3729	General stress protein
APS45_RS07890	COG1546	Belongs to the CinA family
APS45_RS07895	COG3111	PFAM Bacterial OB fold (BOF) protein
APS45_RS07905	COG2814	Major facilitator Superfamily
APS45_RS07940	COG0583	DNA-binding transcription factor activity
APS45_RS07945	COG1012	belongs to the aldehyde dehydrogenase family
APS45_RS07960	COG3781	membrane
APS45_RS07985	COG1773	rubredoxin
APS45_RS08010	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
APS45_RS08015	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
APS45_RS08025	COG2186	Transcriptional regulator
APS45_RS08030	COG1063	alcohol dehydrogenase
APS45_RS08035	COG2271	Major facilitator Superfamily
APS45_RS08060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APS45_RS08065	COG0251	oxidation-reduction process
APS45_RS08120	COG1609	Transcriptional regulator
APS45_RS08125	COG1757	Na H antiporter
APS45_RS08130	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
APS45_RS08145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
APS45_RS08160	COG1764	response to oxidative stress
APS45_RS08180	COG1064	alcohol dehydrogenase
APS45_RS08185	COG2864	formate dehydrogenase
APS45_RS08190	COG0437	4 iron, 4 sulfur cluster binding
APS45_RS08195	COG3383	formate dehydrogenase (NAD+) activity
APS45_RS08195	COG0243	molybdopterin cofactor binding
APS45_RS08200	COG0243	molybdopterin cofactor binding
APS45_RS08200	COG3383	formate dehydrogenase (NAD+) activity
APS45_RS08235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APS45_RS08240	COG1140	nitrate reductase beta subunit
APS45_RS08245	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
APS45_RS08250	COG2181	nitrate reductase activity
APS45_RS08285	COG4772	TonB-dependent receptor
APS45_RS08290	COG1802	Transcriptional regulator
APS45_RS08295	COG2130	NADP-dependent
APS45_RS08305	COG3238	Protein conserved in bacteria
APS45_RS08340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
APS45_RS08345	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
APS45_RS08370	COG0826	peptidase U32
APS45_RS08375	COG1396	sequence-specific DNA binding
APS45_RS08380	COG3135	benzoate transporter
APS45_RS08390	COG0500	methyltransferase
APS45_RS08395	COG1275	C4-dicarboxylate transporter malic acid transport protein
APS45_RS08400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
APS45_RS08405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APS45_RS08415	COG3414	Phosphotransferase system galactitol-specific IIB component
APS45_RS08420	COG3775	system Galactitol-specific IIC component
APS45_RS08425	COG0434	BtpA family
APS45_RS08430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS08435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
APS45_RS08440	COG1349	DNA-binding transcription factor activity
APS45_RS08450	COG1304	FMN binding
APS45_RS08455	COG2353	YceI-like domain
APS45_RS08465	COG2272	Belongs to the type-B carboxylesterase lipase family
APS45_RS08470	COG5383	Protein conserved in bacteria
APS45_RS08475	COG0583	DNA-binding transcription factor activity
APS45_RS08480	COG0840	transmembrane signaling receptor activity
APS45_RS08510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APS45_RS08515	COG0765	amino acid transport
APS45_RS08525	COG0765	amino acid transport
APS45_RS08535	COG0500	methyltransferase
APS45_RS08540	COG3038	cytochrome b561
APS45_RS08545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
APS45_RS08550	COG1643	Atp-dependent helicase
APS45_RS08565	COG3784	Protein of unknown function (DUF1318)
APS45_RS08575	COG2911	Protein conserved in bacteria
APS45_RS08580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APS45_RS08585	COG3187	Heat shock protein
APS45_RS08590	COG3042	response to heat
APS45_RS08600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
APS45_RS08600	COG0674	pyruvate-flavodoxin oxidoreductase activity
APS45_RS08600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
APS45_RS08600	COG1013	pyruvate-flavodoxin oxidoreductase activity
APS45_RS08615	COG2076	Multidrug Resistance protein
APS45_RS08630	COG0513	Belongs to the DEAD box helicase family
APS45_RS08640	COG0840	transmembrane signaling receptor activity
APS45_RS08645	COG2840	Smr protein MutS2
APS45_RS08665	COG3182	Iron-regulated membrane protein
APS45_RS08670	COG0668	transmembrane transport
APS45_RS08690	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APS45_RS08725	COG1309	transcriptional regulator
APS45_RS08730	COG1028	Short-chain dehydrogenase reductase Sdr
APS45_RS08735	COG0656	L-ascorbic acid biosynthetic process
APS45_RS08740	COG0583	DNA-binding transcription factor activity
APS45_RS08750	COG4166	transmembrane transport
APS45_RS08755	COG2866	Carboxypeptidase
APS45_RS08760	COG4948	Mandelate Racemase Muconate Lactonizing
APS45_RS08780	COG3106	COG3106 Predicted ATPase
APS45_RS08785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APS45_RS08795	COG1983	PspC domain protein
APS45_RS08805	COG1842	Phage shock protein A
APS45_RS08810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
APS45_RS08865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APS45_RS08865	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APS45_RS08875	COG5001	Diguanylate cyclase
APS45_RS08885	COG1349	DNA-binding transcription factor activity
APS45_RS08905	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
APS45_RS08910	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
APS45_RS08915	COG0671	phosphoesterase, PA-phosphatase related
APS45_RS08950	COG0616	signal peptide processing
APS45_RS08955	COG1028	Short-chain dehydrogenase reductase Sdr
APS45_RS08970	COG0009	L-threonylcarbamoyladenylate synthase
APS45_RS08990	COG0135	phosphoribosylanthranilate isomerase activity
APS45_RS08990	COG0134	indole-3-glycerol-phosphate synthase activity
APS45_RS09005	COG3729	General stress protein
APS45_RS09010	COG3685	Protein conserved in bacteria
APS45_RS09015	COG3685	Protein conserved in bacteria
APS45_RS09020	COG3546	catalase activity
APS45_RS09030	COG0727	PFAM Uncharacterised protein family (UPF0153)
APS45_RS09055	COG2350	Protein conserved in bacteria
APS45_RS09070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
APS45_RS09100	COG2095	MarC family integral membrane protein
APS45_RS09105	COG1454	alcohol dehydrogenase
APS45_RS09105	COG1012	belongs to the aldehyde dehydrogenase family
APS45_RS09120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
APS45_RS09125	COG0745	RESPONSE REGULATOR receiver
APS45_RS09130	COG1752	Esterase of the alpha-beta hydrolase superfamily
APS45_RS09140	COG0788	formyltetrahydrofolate deformylase activity
APS45_RS09185	COG2181	nitrate reductase activity
APS45_RS09190	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
APS45_RS09195	COG1140	nitrate reductase beta subunit
APS45_RS09200	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APS45_RS09205	COG2223	nitrite transmembrane transporter activity
APS45_RS09210	COG3850	Histidine kinase
APS45_RS09215	COG2197	response regulator
APS45_RS09220	COG4932	domain protein
APS45_RS09225	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
APS45_RS09230	COG4572	Cation transport regulator
APS45_RS09235	COG0387	Pfam Sodium calcium exchanger
APS45_RS09285	COG0659	secondary active sulfate transmembrane transporter activity
APS45_RS09300	COG0012	GTP binding
APS45_RS09310	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
APS45_RS09320	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
APS45_RS09325	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
APS45_RS09330	COG1999	signal sequence binding
APS45_RS09335	COG1773	rubredoxin
APS45_RS09340	COG1271	oxidase subunit
APS45_RS09345	COG1294	oxidase, subunit
APS45_RS09355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
APS45_RS09380	COG1619	proteins homologs of microcin C7 resistance protein MccF
APS45_RS09400	COG2719	SpoVR family
APS45_RS09440	COG0179	Fumarylacetoacetate (FAA) hydrolase
APS45_RS09455	COG2894	cell division
APS45_RS09465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
APS45_RS09475	COG3065	identical protein binding
APS45_RS09485	COG1199	ATP-dependent helicase activity
APS45_RS09490	COG0251	oxidation-reduction process
APS45_RS09510	COG1760	l-serine dehydratase
APS45_RS09515	COG2200	EAL domain
APS45_RS09520	COG1253	flavin adenine dinucleotide binding
APS45_RS09530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APS45_RS09530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS09535	COG3715	PTS system
APS45_RS09540	COG3716	PTS system mannose fructose sorbose family IID component
APS45_RS09555	COG2226	methyltransferase
APS45_RS09560	COG0768	penicillin binding
APS45_RS09590	COG1414	Transcriptional regulator
APS45_RS09595	COG2814	Major facilitator Superfamily
APS45_RS09615	COG1956	GAF domain-containing protein
APS45_RS09620	COG2995	paraquat-inducible protein a
APS45_RS09625	COG3008	intermembrane lipid transfer
APS45_RS09660	COG5562	phage envelope protein
APS45_RS09670	COG0454	-acetyltransferase
APS45_RS09745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
APS45_RS09765	COG1276	copper resistance
APS45_RS09770	COG2372	response to copper ion
APS45_RS09780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
APS45_RS09785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
APS45_RS09790	COG1770	oligopeptidase
APS45_RS09795	COG2979	Protein of unknown function (DUF533)
APS45_RS09805	COG3141	response to X-ray
APS45_RS09815	COG0800	Aldolase
APS45_RS09820	COG0129	dihydroxy-acid dehydratase activity
APS45_RS09825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APS45_RS09830	COG1737	Transcriptional regulator
APS45_RS09840	COG1560	Kdo2-lipid A biosynthetic process
APS45_RS09845	COG0739	heme binding
APS45_RS09850	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
APS45_RS09860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
APS45_RS09895	COG0494	nUDIX hydrolase
APS45_RS09905	COG1335	isochorismatase
APS45_RS09910	COG1801	Protein of unknown function DUF72
APS45_RS09915	COG3788	relative of glutathione S-transferase, MAPEG superfamily
APS45_RS09935	COG3102	Protein conserved in bacteria
APS45_RS09950	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
APS45_RS10050	COG1528	Iron-storage protein
APS45_RS10065	COG1528	Iron-storage protein
APS45_RS10075	COG0814	amino acid
APS45_RS10080	COG3012	SEC-C Motif Domain Protein
APS45_RS10080	COG3318	Belongs to the UPF0149 family
APS45_RS10125	COG2197	response regulator
APS45_RS10140	COG2197	response regulator
APS45_RS10145	COG1126	abc transporter atp-binding protein
APS45_RS10150	COG0765	amino acid transport
APS45_RS10160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APS45_RS10215	COG0425	Belongs to the sulfur carrier protein TusA family
APS45_RS10320	COG5475	Uncharacterized small protein (DUF2158)
APS45_RS10325	COG2354	Protein conserved in bacteria
APS45_RS10330	COG0697	spore germination
APS45_RS10335	COG3727	T/G mismatch-specific endonuclease activity
APS45_RS10340	COG0270	DNA (cytosine-5-)-methyltransferase activity
APS45_RS10345	COG1418	mRNA catabolic process
APS45_RS10355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
APS45_RS10395	COG0582	viral genome integration into host DNA
APS45_RS10435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APS45_RS10465	COG0534	Mate efflux family protein
APS45_RS10505	COG1122	ATPase activity
APS45_RS10635	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
APS45_RS10650	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
APS45_RS10665	COG1454	alcohol dehydrogenase
APS45_RS10665	COG1012	belongs to the aldehyde dehydrogenase family
APS45_RS10670	COG4656	Part of a membrane complex involved in electron transport
APS45_RS10705	COG1289	transmembrane transporter activity
APS45_RS10740	COG2925	Exonuclease
APS45_RS10745	COG0531	amino acid
APS45_RS10750	COG0583	DNA-binding transcription factor activity
APS45_RS10755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
APS45_RS10910	COG2327	Polysaccharide pyruvyl transferase
APS45_RS10915	COG2244	polysaccharide biosynthetic process
APS45_RS10920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
APS45_RS10935	COG0297	glycogen (starch) synthase activity
APS45_RS10945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
APS45_RS10950	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
APS45_RS10955	COG0110	maltose O-acetyltransferase activity
APS45_RS10960	COG1216	Glycosyl transferase, family 2
APS45_RS10970	COG0438	transferase activity, transferring glycosyl groups
APS45_RS10975	COG1045	serine acetyltransferase
APS45_RS10980	COG0463	Glycosyl transferase, family 2
APS45_RS11000	COG1253	flavin adenine dinucleotide binding
APS45_RS11005	COG2982	Protein involved in outer membrane biogenesis
APS45_RS11020	COG3447	MASE1 domain protein
APS45_RS11020	COG5001	Diguanylate cyclase
APS45_RS11020	COG5002	protein histidine kinase activity
APS45_RS11025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APS45_RS11030	COG0443	Heat shock 70 kDa protein
APS45_RS11055	COG2205	protein histidine kinase activity
APS45_RS11060	COG0745	RESPONSE REGULATOR receiver
APS45_RS11080	COG0826	peptidase U32
APS45_RS11110	COG1830	Aldolase
APS45_RS11115	COG2211	Major facilitator Superfamily
APS45_RS11120	COG1397	ADP-ribosylglycohydrolase
APS45_RS11125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APS45_RS11130	COG2188	Transcriptional regulator
APS45_RS11145	COG5455	response to cobalt ion
APS45_RS11150	COG3539	Fimbrial protein
APS45_RS11155	COG3188	usher protein
APS45_RS11160	COG3121	Chaperone
APS45_RS11185	COG4808	Protein conserved in bacteria
APS45_RS11195	COG4807	Protein conserved in bacteria
APS45_RS11205	COG3275	phosphorelay sensor kinase activity
APS45_RS11220	COG1174	glycine betaine transport
APS45_RS11225	COG1125	glycine betaine transport
APS45_RS11230	COG1174	glycine betaine transport
APS45_RS11235	COG1732	Glycine betaine
APS45_RS11245	COG0277	FAD linked oxidase domain protein
APS45_RS11250	COG1686	Belongs to the peptidase S11 family
APS45_RS11260	COG0586	Pfam SNARE associated Golgi protein
APS45_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
APS45_RS11270	COG1538	Outer membrane efflux protein
APS45_RS11275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APS45_RS11280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
APS45_RS11285	COG0625	glutathione transferase activity
APS45_RS11300	COG2271	Major facilitator Superfamily
APS45_RS11315	COG1346	cytolysis
APS45_RS11325	COG2949	membrane
APS45_RS11335	COG0493	'glutamate synthase
APS45_RS11365	COG2311	Membrane
APS45_RS11385	COG1760	l-serine dehydratase
APS45_RS11390	COG0560	Phosphoserine phosphatase
APS45_RS11395	COG2271	Major facilitator Superfamily
APS45_RS11400	COG4771	TonB-dependent receptor
APS45_RS11405	COG0833	amino acid
APS45_RS11410	COG0583	DNA-binding transcription factor activity
APS45_RS11415	COG2855	membrane
APS45_RS11425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APS45_RS11425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APS45_RS11425	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
APS45_RS11430	COG1105	Belongs to the carbohydrate kinase PfkB family
APS45_RS11465	COG0523	cobalamin synthesis protein
APS45_RS11470	COG0671	phosphoesterase, PA-phosphatase related
APS45_RS11475	COG0791	NLP P60 protein
APS45_RS11480	COG2200	EAL domain
APS45_RS11485	COG4166	transmembrane transport
APS45_RS11490	COG4174	ABC transporter (Permease)
APS45_RS11495	COG4239	(ABC) transporter, permease
APS45_RS11500	COG4172	Belongs to the ABC transporter superfamily
APS45_RS11515	COG2814	Major facilitator Superfamily
APS45_RS11525	COG1061	Type III restriction enzyme res subunit
APS45_RS11610	COG1403	HNH endonuclease
APS45_RS11630	COG5301	cellulose 1,4-beta-cellobiosidase activity
APS45_RS11645	COG2197	response regulator
APS45_RS11650	COG3088	subunit of a heme lyase
APS45_RS11650	COG4235	cytochrome complex assembly
APS45_RS11660	COG1138	Cytochrome C-type biogenesis protein
APS45_RS11670	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
APS45_RS11675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
APS45_RS11680	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
APS45_RS11685	COG4133	protoheme IX ABC transporter activity
APS45_RS11690	COG3005	denitrification pathway
APS45_RS11695	COG3043	anaerobic respiration
APS45_RS11700	COG0348	domain, Protein
APS45_RS11705	COG0437	4 iron, 4 sulfur cluster binding
APS45_RS11715	COG3062	negative regulation of establishment of protein localization
APS45_RS11720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
APS45_RS11720	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
APS45_RS11730	COG4615	Cyclic peptide transporter
APS45_RS11755	COG0642	Histidine kinase
APS45_RS11755	COG2198	Histidine kinase
APS45_RS11775	COG4948	Mandelate Racemase Muconate Lactonizing
APS45_RS11805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APS45_RS11810	COG2814	Major facilitator Superfamily
APS45_RS11815	COG0583	DNA-binding transcription factor activity
APS45_RS11820	COG0584	glycerophosphoryl diester phosphodiesterase
APS45_RS11825	COG2271	Major facilitator Superfamily
APS45_RS11830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
APS45_RS11840	COG0247	lactate metabolic process
APS45_RS11860	COG2271	Major facilitator Superfamily
APS45_RS11870	COG1414	Transcriptional regulator
APS45_RS11960	COG1169	isochorismate synthase
APS45_RS11965	COG4575	ribosome binding
APS45_RS11970	COG2153	protein acetylation
APS45_RS11980	COG0835	chemotaxis
APS45_RS11980	COG0784	Response regulator, receiver
APS45_RS11990	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
APS45_RS11995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
APS45_RS12005	COG0839	Belongs to the complex I subunit 6 family
APS45_RS12055	COG0583	DNA-binding transcription factor activity
APS45_RS12060	COG0436	Aminotransferase
APS45_RS12070	COG0490	domain, Protein
APS45_RS12070	COG0471	metal ion transport
APS45_RS12075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APS45_RS12100	COG1288	antiporter activity
APS45_RS12105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APS45_RS12110	COG3959	Transketolase, thiamine diphosphate binding domain
APS45_RS12115	COG3037	sugar-specific permease SgaT UlaA
APS45_RS12125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS12135	COG1609	Transcriptional regulator
APS45_RS12145	COG0622	Phosphoesterase
APS45_RS12150	COG0625	glutathione transferase activity
APS45_RS12155	COG0625	glutathione transferase activity
APS45_RS12160	COG1090	epimerase
APS45_RS12195	COG0833	amino acid
APS45_RS12200	COG3457	Alanine racemase
APS45_RS12205	COG0531	amino acid
APS45_RS12215	COG3829	transcription factor binding
APS45_RS12220	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APS45_RS12225	COG1286	toxin biosynthetic process
APS45_RS12230	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
APS45_RS12235	COG0285	dihydrofolate synthase activity
APS45_RS12245	COG0586	Pfam SNARE associated Golgi protein
APS45_RS12255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APS45_RS12280	COG3423	Transcriptional regulator
APS45_RS12300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
APS45_RS12315	COG3101	peptidyl-lysine hydroxylation
APS45_RS12320	COG0730	response to heat
APS45_RS12345	COG2062	phosphohistidine phosphatase, SixA
APS45_RS12360	COG3691	Protein conserved in bacteria
APS45_RS12375	COG2116	formate transmembrane transporter activity
APS45_RS12385	COG0582	viral genome integration into host DNA
APS45_RS12480	COG1560	Kdo2-lipid A biosynthetic process
APS45_RS12495	COG0436	Aminotransferase
APS45_RS12510	COG3961	Belongs to the TPP enzyme family
APS45_RS12515	COG0667	Aldo Keto reductase
APS45_RS12530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APS45_RS12535	COG2200	EAL domain
APS45_RS12535	COG2199	diguanylate cyclase activity
APS45_RS12550	COG3415	Transposase
APS45_RS12555	COG3415	Transposase
APS45_RS12585	COG0583	DNA-binding transcription factor activity
APS45_RS12595	COG2211	Major facilitator Superfamily
APS45_RS12600	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
APS45_RS12610	COG0583	DNA-binding transcription factor activity
APS45_RS12615	COG0385	Bile acid
APS45_RS12620	COG3530	Putative quorum-sensing-regulated virulence factor
APS45_RS12650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS12705	COG4208	sulfate ABC transporter
APS45_RS12725	COG2837	iron assimilation
APS45_RS12855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APS45_RS12865	COG5342	invasion associated locus B
APS45_RS12880	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
APS45_RS12880	COG0493	'glutamate synthase
APS45_RS12885	COG3850	Histidine kinase
APS45_RS12890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APS45_RS12895	COG1393	Belongs to the ArsC family
APS45_RS12915	COG2321	neutral zinc metallopeptidase
APS45_RS12925	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
APS45_RS12935	COG2716	regulation of RNA biosynthetic process
APS45_RS12940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APS45_RS12945	COG1929	Belongs to the glycerate kinase type-1 family
APS45_RS12950	COG0628	permease
APS45_RS12960	COG1393	Belongs to the ArsC family
APS45_RS12970	COG2233	PERMEase
APS45_RS12985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APS45_RS13000	COG2200	EAL domain
APS45_RS13020	COG2801	Transposase and inactivated derivatives
APS45_RS13030	COG3179	chitinase
APS45_RS13045	COG2246	polysaccharide biosynthetic process
APS45_RS13050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
APS45_RS13050	COG2755	lipolytic protein G-D-S-L family
APS45_RS13220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
APS45_RS13265	COG0517	IMP dehydrogenase activity
APS45_RS13265	COG0516	GMP reductase activity
APS45_RS13300	COG1645	bacterial-type flagellum-dependent swarming motility
APS45_RS13315	COG2976	Protein conserved in bacteria
APS45_RS13355	COG0437	4 iron, 4 sulfur cluster binding
APS45_RS13360	COG0243	molybdopterin cofactor binding
APS45_RS13365	COG4953	penicillin-binding protein 1C
APS45_RS13370	COG2373	Large extracellular alpha-helical protein
APS45_RS13375	COG2897	thiosulfate sulfurtransferase activity
APS45_RS13395	COG2975	iron-sulfur cluster assembly
APS45_RS13400	COG0633	Ferredoxin
APS45_RS13420	COG0822	iron-sulfur transferase activity
APS45_RS13465	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
APS45_RS13475	COG3711	transcriptional antiterminator
APS45_RS13480	COG2814	Major facilitator Superfamily
APS45_RS13495	COG3710	Transcriptional regulator
APS45_RS13500	COG0531	amino acid
APS45_RS13510	COG3104	oligopeptide transport
APS45_RS13515	COG0347	Belongs to the P(II) protein family
APS45_RS13520	COG2204	response regulator
APS45_RS13525	COG3170	Tfp pilus assembly protein FimV
APS45_RS13530	COG2205	protein histidine kinase activity
APS45_RS13555	COG0560	Phosphoserine phosphatase
APS45_RS13560	COG1263	PTS System
APS45_RS13560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APS45_RS13570	COG1737	Transcriptional regulator
APS45_RS13575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APS45_RS13580	COG2223	nitrite transmembrane transporter activity
APS45_RS13585	COG0583	DNA-binding transcription factor activity
APS45_RS13590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
APS45_RS13630	COG3086	response to oxidative stress
APS45_RS13660	COG0513	Belongs to the DEAD box helicase family
APS45_RS13665	COG0583	DNA-binding transcription factor activity
APS45_RS13685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APS45_RS13690	COG3118	belongs to the thioredoxin family
APS45_RS13695	COG3148	PFAM DTW domain containing protein
APS45_RS13705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APS45_RS13710	COG5544	Lipoprotein
APS45_RS13715	COG0477	Major facilitator Superfamily
APS45_RS13745	COG0542	response to heat
APS45_RS13760	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APS45_RS13765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APS45_RS13770	COG1605	Chorismate mutase
APS45_RS13770	COG0077	Prephenate dehydratase
APS45_RS13780	COG0287	Prephenate dehydrogenase
APS45_RS13780	COG1605	Chorismate mutase
APS45_RS13795	COG2199	diguanylate cyclase activity
APS45_RS13820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APS45_RS13825	COG4137	Cytochrome C assembly protein
APS45_RS13830	COG4536	flavin adenine dinucleotide binding
APS45_RS13850	COG0497	DNA recombination
APS45_RS13865	COG2867	negative regulation of translational initiation
APS45_RS13890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APS45_RS13900	COG0582	viral genome integration into host DNA
APS45_RS13905	COG0582	viral genome integration into host DNA
APS45_RS13940	COG4133	protoheme IX ABC transporter activity
APS45_RS13955	COG3423	Transcriptional regulator
APS45_RS13975	COG0673	inositol 2-dehydrogenase activity
APS45_RS13985	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
APS45_RS13990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
APS45_RS14000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APS45_RS14000	COG2190	(PTS) system
APS45_RS14000	COG1263	PTS System
APS45_RS14035	COG2801	Transposase and inactivated derivatives
APS45_RS14045	COG2963	transposase activity
APS45_RS14065	COG2801	Transposase and inactivated derivatives
APS45_RS14090	COG1132	(ABC) transporter
APS45_RS14100	COG2819	hydrolase of the alpha beta superfamily
APS45_RS14120	COG2990	Protein conserved in bacteria
APS45_RS14135	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
APS45_RS14175	COG0579	oxidoreductase
APS45_RS14180	COG1012	belongs to the aldehyde dehydrogenase family
APS45_RS14185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APS45_RS14190	COG1113	amino acid transport
APS45_RS14195	COG1802	Transcriptional regulator
APS45_RS14200	COG1652	LysM domain
APS45_RS14205	COG0401	homolog of Blt101
APS45_RS14210	COG0640	Transcriptional regulator
APS45_RS14215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APS45_RS14240	COG4575	ribosome binding
APS45_RS14250	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APS45_RS14295	COG2814	Major facilitator Superfamily
APS45_RS14300	COG1846	Transcriptional regulator
APS45_RS14305	COG1566	PFAM secretion protein HlyD family protein
APS45_RS14310	COG2814	Major facilitator Superfamily
APS45_RS14330	COG1238	metal cluster binding
APS45_RS14335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APS45_RS14365	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
APS45_RS14385	COG1546	Belongs to the CinA family
APS45_RS14390	COG2951	lytic endotransglycosylase activity
APS45_RS14395	COG3730	PTS system glucitol sorbitol-specific
APS45_RS14400	COG3732	PTS system glucitol sorbitol-specific
APS45_RS14410	COG1028	Short-chain dehydrogenase reductase Sdr
APS45_RS14415	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS14425	COG1349	DNA-binding transcription factor activity
APS45_RS14430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
APS45_RS14430	COG0517	IMP dehydrogenase activity
APS45_RS14450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
APS45_RS14455	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
APS45_RS14465	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
APS45_RS14475	COG3260	NADH ubiquinone oxidoreductase 20
APS45_RS14480	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
APS45_RS14485	COG3261	NADH dehydrogenase
APS45_RS14485	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
APS45_RS14490	COG0650	Formate hydrogenlyase subunit 4
APS45_RS14495	COG0651	ATP synthesis coupled electron transport
APS45_RS14500	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
APS45_RS14515	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
APS45_RS14520	COG0298	carbon dioxide binding
APS45_RS14525	COG0409	Hydrogenase expression formation protein
APS45_RS14530	COG0309	Hydrogenase expression formation protein (HypE)
APS45_RS14550	COG1121	(ABC) transporter
APS45_RS14555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
APS45_RS14560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
APS45_RS14645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APS45_RS14735	COG2207	Transcriptional regulator
APS45_RS14795	COG0477	Major facilitator Superfamily
APS45_RS14805	COG2610	gluconate transmembrane transporter activity
APS45_RS14810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
APS45_RS14815	COG3622	Belongs to the hyi family
APS45_RS14820	COG0235	Class ii aldolase
APS45_RS14830	COG2084	Dehydrogenase
APS45_RS14835	COG1349	DNA-binding transcription factor activity
APS45_RS14845	COG0163	prenyltransferase activity
APS45_RS14850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
APS45_RS14920	COG2234	aminopeptidase activity
APS45_RS14925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
APS45_RS14930	COG1518	maintenance of DNA repeat elements
APS45_RS14945	COG1857	crispr-associated protein
APS45_RS14960	COG1203	CRISPR-associated helicase, Cas3
APS45_RS14980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
APS45_RS14985	COG0720	synthase
APS45_RS14990	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
APS45_RS14990	COG0321	lipoyl(octanoyl) transferase activity
APS45_RS14995	COG0602	queuosine metabolic process
APS45_RS15010	COG3956	TIGRFAM MazG family protein
APS45_RS15015	COG3539	Fimbrial protein
APS45_RS15020	COG3188	usher protein
APS45_RS15025	COG3121	Chaperone
APS45_RS15030	COG3539	Fimbrial protein
APS45_RS15065	COG3609	addiction module antidote protein, CC2985 family
APS45_RS15070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APS45_RS15080	COG2205	protein histidine kinase activity
APS45_RS15080	COG4999	Histidine kinase
APS45_RS15080	COG3850	Histidine kinase
APS45_RS15080	COG3437	response regulator, receiver
APS45_RS15085	COG1929	Belongs to the glycerate kinase type-1 family
APS45_RS15090	COG4948	Mandelate Racemase Muconate Lactonizing
APS45_RS15095	COG4948	Mandelate Racemase Muconate Lactonizing
APS45_RS15100	COG2271	Major facilitator Superfamily
APS45_RS15105	COG0716	FMN binding
APS45_RS15115	COG3098	single-species biofilm formation
APS45_RS15135	COG1611	Belongs to the LOG family
APS45_RS15140	COG0814	amino acid
APS45_RS15145	COG1760	l-serine dehydratase
APS45_RS15155	COG1454	alcohol dehydrogenase
APS45_RS15160	COG0235	Class ii aldolase
APS45_RS15165	COG0738	Major facilitator superfamily
APS45_RS15185	COG1349	DNA-binding transcription factor activity
APS45_RS15195	COG2363	Small membrane protein
APS45_RS15200	COG0583	DNA-binding transcription factor activity
APS45_RS15210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APS45_RS15215	COG2166	iron-sulfur cluster assembly
APS45_RS15220	COG2962	Rard protein
APS45_RS15225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
APS45_RS15230	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
APS45_RS15245	COG0860	N-Acetylmuramoyl-L-alanine amidase
APS45_RS15255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
APS45_RS15260	COG1074	ATP-dependent DNA helicase activity
APS45_RS15270	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
APS45_RS15275	COG4967	type IV pilus modification protein PilV
APS45_RS15285	COG4795	General secretion pathway protein
APS45_RS15290	COG2165	general secretion pathway protein
APS45_RS15330	COG0861	Integral membrane protein TerC family
APS45_RS15340	COG0667	Aldo Keto reductase
APS45_RS15360	COG1609	Transcriptional regulator
APS45_RS15370	COG0583	DNA-binding transcription factor activity
APS45_RS15375	COG1794	racemase activity, acting on amino acids and derivatives
APS45_RS15380	COG2814	Major facilitator Superfamily
APS45_RS15385	COG1028	Short-chain dehydrogenase reductase Sdr
APS45_RS15395	COG0183	Belongs to the thiolase family
APS45_RS15410	COG0814	amino acid
APS45_RS15445	COG3188	usher protein
APS45_RS15465	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
APS45_RS15470	COG1028	Short-chain dehydrogenase reductase Sdr
APS45_RS15475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
APS45_RS15480	COG3775	system Galactitol-specific IIC component
APS45_RS15485	COG3414	Phosphotransferase system galactitol-specific IIB component
APS45_RS15490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS15495	COG1349	DNA-binding transcription factor activity
APS45_RS15500	COG0698	ribose 5-phosphate isomerase
APS45_RS15505	COG3775	system Galactitol-specific IIC component
APS45_RS15510	COG3414	Phosphotransferase system galactitol-specific IIB component
APS45_RS15515	COG2213	PTS system mannitol-specific
APS45_RS15515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS15535	COG0582	viral genome integration into host DNA
APS45_RS15545	COG4942	peptidase
APS45_RS15605	COG1272	protein, Hemolysin III
APS45_RS15615	COG2723	6-phospho-beta-galactosidase activity
APS45_RS15640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
APS45_RS15645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
APS45_RS15650	COG0006	proline dipeptidase activity
APS45_RS15670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APS45_RS15675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
APS45_RS15690	COG2968	Membrane
APS45_RS15700	COG0668	transmembrane transport
APS45_RS15705	COG0191	fructose-bisphosphate aldolase activity
APS45_RS15735	COG1122	ATPase activity
APS45_RS15740	COG1122	ATPase activity
APS45_RS15745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APS45_RS15750	COG0501	Belongs to the peptidase M48B family
APS45_RS15760	COG2267	carboxylic ester hydrolase activity
APS45_RS15765	COG2731	YhcH YjgK YiaL family protein
APS45_RS15770	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
APS45_RS15775	COG1063	alcohol dehydrogenase
APS45_RS15780	COG0246	Mannitol dehydrogenase
APS45_RS15785	COG4948	Mandelate Racemase Muconate Lactonizing
APS45_RS15790	COG2186	Transcriptional regulator
APS45_RS15800	COG1166	arginine decarboxylase activity
APS45_RS15820	COG2814	Major facilitator Superfamily
APS45_RS15830	COG2356	endonuclease I
APS45_RS15835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
APS45_RS15860	COG2805	Type II/IV secretion system protein
APS45_RS15865	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APS45_RS15870	COG0762	integral membrane protein
APS45_RS15885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
APS45_RS15895	COG0252	asparaginase activity
APS45_RS15905	COG3171	Protein conserved in bacteria
APS45_RS15930	COG2211	Major facilitator Superfamily
APS45_RS15935	COG1982	Orn Lys Arg decarboxylase major
APS45_RS15945	COG1811	Na channel or pump
APS45_RS15960	COG0427	acetyl-CoA hydrolase
APS45_RS15965	COG2030	dehydratase
APS45_RS15970	COG2301	Belongs to the HpcH HpaI aldolase family
APS45_RS16000	COG0531	amino acid
APS45_RS16010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
APS45_RS16015	COG1012	belongs to the aldehyde dehydrogenase family
APS45_RS16040	COG2271	Major facilitator Superfamily
APS45_RS16050	COG0246	Mannitol dehydrogenase
APS45_RS16065	COG0754	glutathionylspermidine amidase activity
APS45_RS16070	COG0625	glutathione transferase activity
APS45_RS16080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
APS45_RS16085	COG0298	carbon dioxide binding
APS45_RS16095	COG1773	rubredoxin
APS45_RS16100	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
APS45_RS16105	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
APS45_RS16110	COG5557	Pfam Polysulphide reductase, NrfD
APS45_RS16115	COG0437	4 iron, 4 sulfur cluster binding
APS45_RS16120	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
APS45_RS16130	COG0840	transmembrane signaling receptor activity
APS45_RS16155	COG1028	Short-chain dehydrogenase reductase Sdr
APS45_RS16160	COG0848	biopolymer transport protein
APS45_RS16185	COG2207	Transcriptional regulator
APS45_RS16190	COG1979	alcohol dehydrogenase
APS45_RS16200	COG0471	metal ion transport
APS45_RS16250	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
APS45_RS16255	COG3111	PFAM Bacterial OB fold (BOF) protein
APS45_RS16270	COG2249	NAD(P)H dehydrogenase (quinone) activity
APS45_RS16275	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
APS45_RS16285	COG3150	esterase
APS45_RS16290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
APS45_RS16295	COG3151	Protein conserved in bacteria
APS45_RS16300	COG0494	nUDIX hydrolase
APS45_RS16315	COG0754	glutathionylspermidine amidase activity
APS45_RS16320	COG3384	dioxygenase
APS45_RS16365	COG1585	Membrane protein implicated in regulation of membrane protease activity
APS45_RS16370	COG2268	Band 7 protein
APS45_RS16385	COG3025	triphosphatase activity
APS45_RS16390	COG4991	sh3 domain protein
APS45_RS16405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APS45_RS16420	COG0828	Belongs to the bacterial ribosomal protein bS21 family
APS45_RS16445	COG2375	cellular response to nickel ion
APS45_RS16450	COG1695	Transcriptional regulator
APS45_RS16455	COG0840	transmembrane signaling receptor activity
APS45_RS16460	COG0840	transmembrane signaling receptor activity
APS45_RS16470	COG1902	pentaerythritol trinitrate reductase activity
APS45_RS16470	COG0446	pyridine nucleotide-disulphide oxidoreductase
APS45_RS16480	COG1451	nucleotide metabolic process
APS45_RS16485	COG2949	membrane
APS45_RS16490	COG0673	inositol 2-dehydrogenase activity
APS45_RS16505	COG0586	Pfam SNARE associated Golgi protein
APS45_RS16515	COG1422	Protein of unknown function (DUF1090)
APS45_RS16520	COG4575	ribosome binding
APS45_RS16525	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
APS45_RS16535	COG2259	Doxx family
APS45_RS16540	COG0435	Glutathione S-transferase
APS45_RS16545	COG3152	Membrane
APS45_RS16550	COG0583	DNA-binding transcription factor activity
APS45_RS16555	COG1741	Belongs to the pirin family
APS45_RS16570	COG0814	amino acid
APS45_RS16575	COG1760	l-serine dehydratase
APS45_RS16580	COG1882	Formate acetyltransferase
APS45_RS16600	COG0583	DNA-binding transcription factor activity
APS45_RS16610	COG1929	Belongs to the glycerate kinase type-1 family
APS45_RS16615	COG2084	Dehydrogenase
APS45_RS16625	COG2721	sulfolactate sulfo-lyase activity
APS45_RS16640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS16645	COG3414	Phosphotransferase system galactitol-specific IIB component
APS45_RS16650	COG3775	system Galactitol-specific IIC component
APS45_RS16655	COG1063	alcohol dehydrogenase
APS45_RS16665	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APS45_RS16670	COG3107	peptidoglycan biosynthetic process
APS45_RS16685	COG2823	Periplasmic or secreted lipoprotein
APS45_RS16690	COG0702	epimerase
APS45_RS16695	COG0693	protein deglycase activity
APS45_RS16710	COG3153	acetyltransferase
APS45_RS16715	COG3154	lipid carrier protein
APS45_RS16720	COG0826	peptidase U32
APS45_RS16725	COG0826	peptidase U32
APS45_RS16730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APS45_RS16735	COG0814	amino acid
APS45_RS16740	COG0513	Belongs to the DEAD box helicase family
APS45_RS16805	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
APS45_RS16815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
APS45_RS16830	COG1534	Rna-binding protein
APS45_RS16845	COG2027	D-alanyl-D-alanine carboxypeptidase
APS45_RS16855	COG0697	spore germination
APS45_RS16870	COG0142	geranyltranstransferase activity
APS45_RS16875	COG3423	Transcriptional regulator
APS45_RS16885	COG5007	Belongs to the BolA IbaG family
APS45_RS16890	COG3113	response to antibiotic
APS45_RS16895	COG2854	intermembrane phospholipid transfer
APS45_RS16900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
APS45_RS16905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
APS45_RS16910	COG1127	ABC transporter
APS45_RS16915	COG0530	calcium, potassium:sodium antiporter activity
APS45_RS16925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
APS45_RS16930	COG3117	lipopolysaccharide transmembrane transporter activity
APS45_RS16935	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
APS45_RS16940	COG1137	ATPase activity
APS45_RS16965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS16970	COG0515	serine threonine protein kinase
APS45_RS16980	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
APS45_RS16985	COG5002	protein histidine kinase activity
APS45_RS16985	COG2198	Histidine kinase
APS45_RS16985	COG0784	Response regulator, receiver
APS45_RS16990	COG1242	4 iron, 4 sulfur cluster binding
APS45_RS17000	COG0069	glutamate synthase activity
APS45_RS17000	COG0070	glutamate synthase
APS45_RS17000	COG0067	glutamate synthase
APS45_RS17005	COG0493	'glutamate synthase
APS45_RS17010	COG4804	nuclease activity
APS45_RS17015	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
APS45_RS17020	COG0402	S-adenosylhomocysteine deaminase activity
APS45_RS17025	COG2731	YhcH YjgK YiaL family protein
APS45_RS17055	COG2969	positive regulation of protein catabolic process
APS45_RS17060	COG0625	glutathione transferase activity
APS45_RS17075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
APS45_RS17080	COG3105	Protein conserved in bacteria
APS45_RS17085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APS45_RS17105	COG5016	pyruvate
APS45_RS17105	COG0511	ligase activity, forming carbon-carbon bonds
APS45_RS17115	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
APS45_RS17120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
APS45_RS17125	COG0471	metal ion transport
APS45_RS17135	COG2188	Transcriptional regulator
APS45_RS17160	COG2732	(Barnase) inhibitor
APS45_RS17180	COG0583	DNA-binding transcription factor activity
APS45_RS17185	COG0312	modulator of DNA gyrase
APS45_RS17190	COG3164	Protein of unknown function
APS45_RS17205	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
APS45_RS17210	COG1792	Involved in formation and maintenance of cell shape
APS45_RS17215	COG1077	Cell shape determining protein MreB Mrl
APS45_RS17225	COG2199	diguanylate cyclase activity
APS45_RS17225	COG2200	EAL domain
APS45_RS17230	COG0604	alcohol dehydrogenase
APS45_RS17245	COG0511	ligase activity, forming carbon-carbon bonds
APS45_RS17250	COG0439	Biotin carboxylase
APS45_RS17255	COG3924	membrane
APS45_RS17260	COG4145	pantothenate transmembrane transporter activity
APS45_RS17280	COG2189	Belongs to the N(4) N(6)-methyltransferase family
APS45_RS17295	COG1309	transcriptional regulator
APS45_RS17300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APS45_RS17305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APS45_RS17350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
APS45_RS17370	COG0551	DNA topoisomerase type I activity
APS45_RS17380	COG0758	DNA mediated transformation
APS45_RS17410	COG3036	rescue of stalled ribosome
APS45_RS17415	COG0789	Transcriptional regulator
APS45_RS17455	COG0201	protein transport
APS45_RS17535	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APS45_RS17560	COG0051	transcription antitermination factor activity, RNA binding
APS45_RS17615	COG2964	Protein conserved in bacteria
APS45_RS17620	COG0545	Peptidyl-prolyl cis-trans isomerase
APS45_RS17630	COG1047	Peptidyl-prolyl cis-trans
APS45_RS17635	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
APS45_RS17650	COG0488	(ABC) transporter
APS45_RS17665	COG0429	hydrolase of the alpha beta-hydrolase fold
APS45_RS17675	COG3954	Phosphoribulokinase
APS45_RS17680	COG1765	OsmC-like protein
APS45_RS17690	COG1289	transmembrane transporter activity
APS45_RS17725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
APS45_RS17765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
APS45_RS17770	COG0338	D12 class N6 adenine-specific DNA methyltransferase
APS45_RS17775	COG3266	domain, Protein
APS45_RS17790	COG4796	Type ii and iii secretion system protein
APS45_RS17805	COG3166	PFAM Fimbrial assembly family protein
APS45_RS17810	COG4972	Pilus assembly protein
APS45_RS17815	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
APS45_RS17820	COG0494	nUDIX hydrolase
APS45_RS17830	COG1011	Hydrolase
APS45_RS17835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
APS45_RS17845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
APS45_RS17870	COG2183	response to ionizing radiation
APS45_RS17875	COG1918	ferrous iron import across plasma membrane
APS45_RS17890	COG5464	transposase or invertase
APS45_RS17910	COG2610	gluconate transmembrane transporter activity
APS45_RS17915	COG1640	4-alpha-glucanotransferase
APS45_RS17920	COG0058	SHG alpha-glucan phosphorylase activity
APS45_RS17930	COG3041	Addiction module toxin RelE StbE family
APS45_RS17935	COG3077	Addiction module antitoxin, RelB DinJ family
APS45_RS17945	COG1690	Belongs to the RtcB family
APS45_RS17955	COG4650	regulator
APS45_RS17960	COG1349	DNA-binding transcription factor activity
APS45_RS17975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
APS45_RS17990	COG0371	Dehydrogenase
APS45_RS18000	COG0129	dihydroxy-acid dehydratase activity
APS45_RS18005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APS45_RS18010	COG1414	Transcriptional regulator
APS45_RS18015	COG0058	SHG alpha-glucan phosphorylase activity
APS45_RS18045	COG2610	gluconate transmembrane transporter activity
APS45_RS18050	COG3265	gluconokinase activity
APS45_RS18055	COG1609	Transcriptional regulator
APS45_RS18060	COG1741	Belongs to the pirin family
APS45_RS18065	COG0673	inositol 2-dehydrogenase activity
APS45_RS18070	COG1247	-acetyltransferase
APS45_RS18075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APS45_RS18090	COG1735	metal-dependent hydrolase with the TIM-barrel fold
APS45_RS18095	COG0405	Gamma-glutamyltransferase
APS45_RS18105	COG0584	glycerophosphoryl diester phosphodiesterase
APS45_RS18180	COG2177	Part of the ABC transporter FtsEX involved in
APS45_RS18185	COG2884	Cell division ATP-binding protein ftsE
APS45_RS18190	COG0552	protein localization to endoplasmic reticulum
APS45_RS18195	COG0742	ribosomal rna small subunit methyltransferase
APS45_RS18200	COG3776	membrane
APS45_RS18210	COG3714	YhhN family
APS45_RS18230	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
APS45_RS18245	COG0628	permease
APS45_RS18250	COG2091	lysine biosynthetic process via aminoadipic acid
APS45_RS18260	COG0842	Transport permease protein
APS45_RS18265	COG1129	ABC transporter
APS45_RS18265	COG0842	Transport permease protein
APS45_RS18270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APS45_RS18275	COG2081	HI0933 family
APS45_RS18280	COG0306	phosphate transporter
APS45_RS18310	COG0671	phosphoesterase, PA-phosphatase related
APS45_RS18315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
APS45_RS18320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
APS45_RS18330	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
APS45_RS18335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APS45_RS18340	COG2222	sugar isomerase
APS45_RS18345	COG2188	Transcriptional regulator
APS45_RS18365	COG2197	response regulator
APS45_RS18370	COG0583	DNA-binding transcription factor activity
APS45_RS18375	COG1295	ribonuclease BN
APS45_RS18380	COG0477	Major facilitator Superfamily
APS45_RS18385	COG2982	Protein involved in outer membrane biogenesis
APS45_RS18390	COG2200	EAL domain
APS45_RS18395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APS45_RS18410	COG2199	diguanylate cyclase activity
APS45_RS18410	COG2200	EAL domain
APS45_RS18465	COG2873	o-acetylhomoserine
APS45_RS18470	COG0814	amino acid
APS45_RS18475	COG4608	Belongs to the ABC transporter superfamily
APS45_RS18480	COG0444	Belongs to the ABC transporter superfamily
APS45_RS18485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
APS45_RS18490	COG0601	transmembrane transport
APS45_RS18495	COG0747	negative chemotaxis
APS45_RS18510	COG1609	Transcriptional regulator
APS45_RS18555	COG5571	outer membrane autotransporter
APS45_RS18560	COG2818	Glycosylase
APS45_RS18565	COG0456	acetyltransferase
APS45_RS18570	COG0243	molybdopterin cofactor binding
APS45_RS18575	COG2885	chlorophyll binding
APS45_RS18590	COG2944	sequence-specific DNA binding
APS45_RS18595	COG1278	Cold shock
APS45_RS18635	COG3274	enterobacterial common antigen metabolic process
APS45_RS18640	COG4682	membrane
APS45_RS18645	COG1070	Carbohydrate kinase
APS45_RS18655	COG2207	Transcriptional regulator
APS45_RS18655	COG1609	Transcriptional regulator
APS45_RS18660	COG2992	FlgJ-related protein
APS45_RS18670	COG0366	Alpha amylase catalytic
APS45_RS18675	COG3977	Valine--pyruvate aminotransferase
APS45_RS18680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
APS45_RS18685	COG1414	Transcriptional regulator
APS45_RS18695	COG2731	YhcH YjgK YiaL family protein
APS45_RS18705	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
APS45_RS18710	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
APS45_RS18715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
APS45_RS18720	COG1070	Carbohydrate kinase
APS45_RS18725	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
APS45_RS18730	COG3623	hexulose-6-phosphate isomerase
APS45_RS18735	COG0235	Class ii aldolase
APS45_RS18750	COG1012	belongs to the aldehyde dehydrogenase family
APS45_RS18755	COG1940	carbohydrate kinase activity
APS45_RS18760	COG3276	selenocysteine insertion sequence binding
APS45_RS18770	COG0625	glutathione transferase activity
APS45_RS18775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS18775	COG2213	PTS system mannitol-specific
APS45_RS18785	COG3722	fumarate hydratase activity
APS45_RS18815	COG2186	Transcriptional regulator
APS45_RS18825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
APS45_RS18830	COG1609	Transcriptional regulator
APS45_RS18840	COG2271	Major facilitator Superfamily
APS45_RS18860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
APS45_RS18865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APS45_RS18875	COG4942	peptidase
APS45_RS18880	COG2861	carbohydrate metabolic process
APS45_RS18885	COG1216	Glycosyl transferase, family 2
APS45_RS18960	COG0438	transferase activity, transferring glycosyl groups
APS45_RS18965	COG0859	PFAM glycosyl transferase family 9
APS45_RS18970	COG1519	Transferase
APS45_RS19000	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APS45_RS19025	COG1561	YicC-like family, N-terminal region
APS45_RS19030	COG0583	DNA-binding transcription factor activity
APS45_RS19040	COG2860	membrane
APS45_RS19060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APS45_RS19065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APS45_RS19070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APS45_RS19080	COG0786	glutamate:sodium symporter activity
APS45_RS19085	COG2233	PERMEase
APS45_RS19090	COG2982	Protein involved in outer membrane biogenesis
APS45_RS19095	COG1501	Belongs to the glycosyl hydrolase 31 family
APS45_RS19100	COG2211	Major facilitator Superfamily
APS45_RS19115	COG0419	ATPase involved in DNA repair
APS45_RS19130	COG2771	luxR family
APS45_RS19145	COG3710	Transcriptional regulator
APS45_RS19150	COG1335	isochorismatase
APS45_RS19175	COG5464	transposase or invertase
APS45_RS19190	COG3716	PTS system mannose fructose sorbose family IID component
APS45_RS19195	COG3715	PTS system
APS45_RS19200	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS19200	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APS45_RS19220	COG2723	6-phospho-beta-galactosidase activity
APS45_RS19255	COG3775	system Galactitol-specific IIC component
APS45_RS19260	COG3414	Phosphotransferase system galactitol-specific IIB component
APS45_RS19265	COG3711	transcriptional antiterminator
APS45_RS19265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS19270	COG2188	Transcriptional regulator
APS45_RS19305	COG0738	Major facilitator superfamily
APS45_RS19315	COG1349	DNA-binding transcription factor activity
APS45_RS19320	COG0440	acetolactate synthase activity
APS45_RS19325	COG0028	Belongs to the TPP enzyme family
APS45_RS19345	COG2814	Major facilitator Superfamily
APS45_RS19355	COG0583	DNA-binding transcription factor activity
APS45_RS19360	COG2610	gluconate transmembrane transporter activity
APS45_RS19370	COG0641	radical SAM
APS45_RS19380	COG2149	membrane
APS45_RS19400	COG5645	(Lipo)protein
APS45_RS19405	COG0823	Involved in the tonB-independent uptake of proteins
APS45_RS19410	COG4235	cytochrome complex assembly
APS45_RS19410	COG3088	subunit of a heme lyase
APS45_RS19420	COG1138	Cytochrome C-type biogenesis protein
APS45_RS19430	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
APS45_RS19435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
APS45_RS19440	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
APS45_RS19445	COG4133	protoheme IX ABC transporter activity
APS45_RS19450	COG1858	cytochrome C peroxidase
APS45_RS19465	COG3005	denitrification pathway
APS45_RS19470	COG0745	RESPONSE REGULATOR receiver
APS45_RS19475	COG1879	ABC-type sugar transport system periplasmic component
APS45_RS19480	COG2198	Histidine kinase
APS45_RS19480	COG2205	protein histidine kinase activity
APS45_RS19480	COG0784	Response regulator, receiver
APS45_RS19485	COG2271	Major facilitator Superfamily
APS45_RS19495	COG0800	Aldolase
APS45_RS19500	COG3734	2-keto-3-deoxy-galactonokinase
APS45_RS19505	COG2186	Transcriptional regulator
APS45_RS19510	COG0561	phosphatase activity
APS45_RS19515	COG2271	Major facilitator Superfamily
APS45_RS19520	COG4948	Mandelate Racemase Muconate Lactonizing
APS45_RS19585	COG2091	lysine biosynthetic process via aminoadipic acid
APS45_RS19590	COG0431	NADPH-dependent FMN reductase
APS45_RS19595	COG2252	PERMEase
APS45_RS19600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APS45_RS19605	COG0704	Plays a role in the regulation of phosphate uptake
APS45_RS19615	COG0581	inorganic phosphate transmembrane transporter activity
APS45_RS19620	COG0573	inorganic phosphate transmembrane transporter activity
APS45_RS19625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
APS45_RS19630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APS45_RS19630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APS45_RS19630	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
APS45_RS19635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APS45_RS19640	COG4533	DNA binding
APS45_RS19700	COG3312	ion transport
APS45_RS19715	COG0716	FMN binding
APS45_RS19720	COG1522	sequence-specific DNA binding
APS45_RS19755	COG1172	Belongs to the binding-protein-dependent transport system permease family
APS45_RS19765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APS45_RS19770	COG1609	Transcriptional regulator
APS45_RS19775	COG0477	Major facilitator Superfamily
APS45_RS19780	COG2186	Transcriptional regulator
APS45_RS19840	COG3978	acetolactate synthase activity
APS45_RS19905	COG3118	belongs to the thioredoxin family
APS45_RS19935	COG1088	dTDP-glucose 4,6-dehydratase activity
APS45_RS19940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APS45_RS19940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APS45_RS19945	COG0456	acetyltransferase
APS45_RS19950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
APS45_RS19955	COG2244	polysaccharide biosynthetic process
APS45_RS20000	COG3071	HemY protein
APS45_RS20005	COG2959	enzyme of heme biosynthesis
APS45_RS20050	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
APS45_RS20055	COG1011	Hydrolase
APS45_RS20100	COG1280	lysine exporter protein (LysE YggA)
APS45_RS20110	COG2267	carboxylic ester hydrolase activity
APS45_RS20115	COG0561	phosphatase activity
APS45_RS20135	COG0641	radical SAM
APS45_RS20180	COG0805	protein transport
APS45_RS20225	COG1739	Uncharacterized protein family UPF0029
APS45_RS20270	COG1763	Mo-molybdopterin cofactor biosynthetic process
APS45_RS20280	COG3084	Protein conserved in bacteria
APS45_RS20295	COG0204	Acyl-transferase
APS45_RS20360	COG2211	Major facilitator Superfamily
APS45_RS20370	COG1501	Belongs to the glycosyl hydrolase 31 family
APS45_RS20380	COG2017	converts alpha-aldose to the beta-anomer
APS45_RS20390	COG3684	Belongs to the aldolase LacD family
APS45_RS20400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APS45_RS20405	COG1349	DNA-binding transcription factor activity
APS45_RS20410	COG1011	Hydrolase
APS45_RS20425	COG0456	acetyltransferase
APS45_RS20430	COG5499	transcription regulator containing HTH domain
APS45_RS20435	COG4680	protein conserved in bacteria
APS45_RS20445	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
APS45_RS20460	COG2864	formate dehydrogenase
APS45_RS20465	COG0437	4 iron, 4 sulfur cluster binding
APS45_RS20470	COG0243	molybdopterin cofactor binding
APS45_RS20470	COG3383	formate dehydrogenase (NAD+) activity
APS45_RS20475	COG3383	formate dehydrogenase (NAD+) activity
APS45_RS20475	COG0243	molybdopterin cofactor binding
APS45_RS20500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
APS45_RS20515	COG1454	alcohol dehydrogenase
APS45_RS20565	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
APS45_RS20575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
APS45_RS20580	COG2258	MOSC domain
APS45_RS20595	COG2205	protein histidine kinase activity
APS45_RS20600	COG0745	RESPONSE REGULATOR receiver
APS45_RS20605	COG3678	ATP-independent chaperone mediated protein folding
APS45_RS20630	COG2211	Major facilitator Superfamily
APS45_RS20645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
APS45_RS20660	COG1070	Carbohydrate kinase
APS45_RS20715	COG3152	Membrane
APS45_RS20725	COG1494	fructose-1,6-bisphosphatase
APS45_RS20735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
APS45_RS20750	COG1575	Belongs to the MenA family. Type 1 subfamily
APS45_RS20765	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
APS45_RS20770	COG1609	Transcriptional regulator
APS45_RS20775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APS45_RS20800	COG0626	cystathionine gamma-synthase activity
APS45_RS20805	COG0460	homoserine dehydrogenase
APS45_RS20805	COG0527	aspartate kinase activity
APS45_RS20810	COG0668	transmembrane transport
APS45_RS20825	COG0737	Belongs to the 5'-nucleotidase family
APS45_RS20840	COG3738	Protein conserved in bacteria
APS45_RS20845	COG0371	Dehydrogenase
APS45_RS20855	COG2207	Transcriptional regulator
APS45_RS20890	COG0583	DNA-binding transcription factor activity
APS45_RS21000	COG0250	Participates in transcription elongation, termination and antitermination
APS45_RS21060	COG2104	thiamine diphosphate biosynthetic process
APS45_RS21065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
APS45_RS21130	COG0151	Belongs to the GarS family
APS45_RS21170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
APS45_RS21215	COG3122	Protein conserved in bacteria
APS45_RS21260	COG5301	cellulose 1,4-beta-cellobiosidase activity
APS45_RS21290	COG2246	polysaccharide biosynthetic process
APS45_RS21365	COG0527	aspartate kinase activity
APS45_RS21390	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APS45_RS21445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
APS45_RS21455	COG0534	Mate efflux family protein
APS45_RS21470	COG0735	belongs to the Fur family
APS45_RS21520	COG2315	Protein conserved in bacteria
APS45_RS21585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
APS45_RS21605	COG2252	PERMEase
APS45_RS21610	COG0025	NhaP-type Na H and K H
APS45_RS21615	COG0583	DNA-binding transcription factor activity
APS45_RS21620	COG1380	Effector of murein hydrolase LrgA
APS45_RS21625	COG1346	cytolysis
APS45_RS21635	COG3162	membrane
APS45_RS21640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
APS45_RS21655	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
APS45_RS21660	COG0437	4 iron, 4 sulfur cluster binding
APS45_RS21665	COG3301	Polysulphide reductase, NrfD
APS45_RS21670	COG1138	Cytochrome C-type biogenesis protein
APS45_RS21675	COG3088	subunit of a heme lyase
APS45_RS21680	COG4235	cytochrome complex assembly
APS45_RS21685	COG1301	dicarboxylic acid transport
APS45_RS21690	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
APS45_RS21695	COG3383	formate dehydrogenase (NAD+) activity
APS45_RS21700	COG3383	formate dehydrogenase (NAD+) activity
APS45_RS21715	COG2764	glyoxalase bleomycin resistance protein dioxygenase
APS45_RS21720	COG2824	Alkylphosphonate utilization operon protein PhnA
APS45_RS21745	COG0531	amino acid
APS45_RS21750	COG2207	Transcriptional regulator
APS45_RS21760	COG1982	Orn Lys Arg decarboxylase major
APS45_RS21765	COG2169	Transcriptional regulator
APS45_RS21780	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
APS45_RS21780	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
APS45_RS21785	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
APS45_RS21795	COG4565	transcriptional regulatory protein
APS45_RS21800	COG3290	protein histidine kinase activity
APS45_RS21805	COG0243	molybdopterin cofactor binding
APS45_RS21810	COG0437	4 iron, 4 sulfur cluster binding
APS45_RS21815	COG3302	dmso reductase anchor subunit
APS45_RS21820	COG3381	protein complex oligomerization
APS45_RS21835	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
APS45_RS21840	COG2197	response regulator
APS45_RS21860	COG2801	Transposase and inactivated derivatives
APS45_RS21875	COG3328	transposase activity
APS45_RS21880	COG3328	transposase activity
APS45_RS21895	COG1309	transcriptional regulator
APS45_RS21910	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
APS45_RS21915	COG1027	Aspartate ammonia-lyase
APS45_RS21925	COG3030	protein affecting phage T7 exclusion by the F plasmid
APS45_RS21930	COG0531	amino acid
APS45_RS21970	COG5510	response to toxic substance
APS45_RS22000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
APS45_RS22005	COG1053	succinate dehydrogenase
APS45_RS22025	COG1511	domain protein
APS45_RS22025	COG3264	Mechanosensitive ion channel
APS45_RS22045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APS45_RS22070	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APS45_RS22070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
APS45_RS22075	COG0802	atpase or kinase
APS45_RS22100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APS45_RS22105	COG0330	HflC and HflK could
APS45_RS22110	COG0330	HflC and HflK could
APS45_RS22115	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
APS45_RS22130	COG0557	exoribonuclease II activity
APS45_RS22140	COG3789	protein conserved in bacteria
APS45_RS22145	COG1842	Phage shock protein A
APS45_RS22160	COG3766	membrane
APS45_RS22165	COG5463	Belongs to the UPF0441 family
APS45_RS22170	COG0754	glutathionylspermidine amidase activity
APS45_RS22175	COG1960	acyl-CoA dehydrogenase activity
APS45_RS22185	COG3650	response to hydrogen peroxide
APS45_RS22190	COG1073	alpha beta
APS45_RS22205	COG3037	sugar-specific permease SgaT UlaA
APS45_RS22255	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APS45_RS22270	COG3061	Opacity-associated protein A
APS45_RS22275	COG0545	Peptidyl-prolyl cis-trans isomerase
APS45_RS22280	COG1113	amino acid transport
APS45_RS22290	COG0697	spore germination
APS45_RS22295	COG0702	epimerase
APS45_RS22300	COG1733	regulation of RNA biosynthetic process
APS45_RS22315	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
APS45_RS22325	COG1253	flavin adenine dinucleotide binding
APS45_RS22345	COG2105	PFAM AIG2 family protein
APS45_RS22350	COG2271	Major facilitator Superfamily
APS45_RS22355	COG3964	amidohydrolase
APS45_RS22370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
APS45_RS22380	COG0312	modulator of DNA gyrase
APS45_RS22415	COG3964	amidohydrolase
APS45_RS22430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APS45_RS22430	COG3711	transcriptional antiterminator
APS45_RS22435	COG3077	Addiction module antitoxin, RelB DinJ family
APS45_RS22440	COG2026	Addiction module toxin, RelE StbE family
APS45_RS22460	COG0366	Alpha amylase catalytic
APS45_RS22465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APS45_RS22465	COG1263	PTS System
APS45_RS22505	COG1438	arginine binding
APS45_RS22510	COG1288	antiporter activity
APS45_RS22530	COG2731	YhcH YjgK YiaL family protein
APS45_RS22575	COG2927	DNA polymerase III (CHI subunit)
APS45_RS22590	COG0795	lipopolysaccharide-transporting ATPase activity
APS45_RS22595	COG0795	lipopolysaccharide-transporting ATPase activity
APS45_RS22600	COG1609	Transcriptional regulator
APS45_RS22605	COG2610	gluconate transmembrane transporter activity
APS45_RS22610	COG1028	Short-chain dehydrogenase reductase Sdr
APS45_RS22615	COG1063	alcohol dehydrogenase
APS45_RS22620	COG3265	gluconokinase activity
APS45_RS22625	COG1064	alcohol dehydrogenase
APS45_RS22635	COG0582	viral genome integration into host DNA
APS45_RS22650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
APS45_RS22660	COG1111	helicase
APS45_RS22660	COG1205	dead DEAH box helicase
APS45_RS22665	COG0210	DNA helicase
APS45_RS22690	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
APS45_RS22720	COG0412	Dienelactone hydrolase
APS45_RS22725	COG2186	Transcriptional regulator
APS45_RS22750	COG0583	DNA-binding transcription factor activity
APS45_RS22755	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APS45_RS22760	COG0700	Nucleoside recognition
APS45_RS22765	COG3366	ferrous iron transmembrane transporter activity
APS45_RS22775	COG0477	Major facilitator Superfamily
APS45_RS22780	COG2733	membrane
APS45_RS22790	COG5464	transposase or invertase
APS45_RS22790	COG5464	transposase or invertase
APS45_RS22795	COG1012	belongs to the aldehyde dehydrogenase family
APS45_RS22830	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
APS45_RS22835	COG1715	Restriction endonuclease
APS45_RS22850	COG0523	cobalamin synthesis protein
APS45_RS22855	COG2879	small protein
APS45_RS22860	COG1966	Carbon starvation protein
APS45_RS22865	COG0840	transmembrane signaling receptor activity
APS45_RS22880	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APS45_RS22885	COG3715	PTS system
APS45_RS22890	COG3716	PTS system mannose fructose sorbose family IID component
APS45_RS22895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
APS45_RS22915	COG1484	DNA-dependent DNA replication
APS45_RS22930	COG2966	Psort location CytoplasmicMembrane, score
APS45_RS22935	COG2197	response regulator
APS45_RS22940	COG2197	response regulator
APS45_RS22945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APS45_RS22950	COG4114	ferric iron reductase
APS45_RS22955	COG3706	GGDEF domain
APS45_RS22985	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
APS45_RS22995	COG1011	Hydrolase
APS45_RS23005	COG2823	Periplasmic or secreted lipoprotein
APS45_RS23015	COG4667	esterase of the alpha-beta hydrolase superfamily
APS45_RS23020	COG0084	hydrolase, TatD family'
APS45_RS23025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APS45_RS23030	COG1328	CTP reductase activity
APS45_RS23060	COG3188	usher protein
APS45_RS23065	COG3121	Chaperone
APS45_RS23070	COG3539	Fimbrial protein
APS45_RS23085	COG3726	membrane protein affecting hemolysin expression
APS45_RS23090	COG0560	Phosphoserine phosphatase
APS45_RS23105	COG0488	(ABC) transporter
APS45_RS23130	COG2207	Transcriptional regulator
APS45_RS23130	COG3708	Transcriptional regulator
APS45_RS23135	COG3045	CreA protein
APS45_RS23140	COG0745	RESPONSE REGULATOR receiver
APS45_RS23145	COG2205	protein histidine kinase activity
APS45_RS23150	COG4452	Inner membrane protein CreD
APS45_RS23170	COG3121	Chaperone
APS45_RS23190	COG0745	RESPONSE REGULATOR receiver
APS45_RS23200	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
APS45_RS23215	COG0460	homoserine dehydrogenase
APS45_RS23215	COG0527	aspartate kinase activity
APS45_RS23420	COG0460	homoserine dehydrogenase
APS45_RS23420	COG0527	aspartate kinase activity
APS45_RS23425	COG0460	homoserine dehydrogenase
APS45_RS23425	COG0527	aspartate kinase activity
APS45_RS23830	COG0460	homoserine dehydrogenase
APS45_RS23830	COG0527	aspartate kinase activity
APS45_RS23845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine