locus-tag class description EIL75_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EIL75_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EIL75_RS00030 ENOG4105CXK mandelate racemase muconate lactonizing EIL75_RS00035 ENOG4105DJB Major Facilitator Superfamily EIL75_RS00040 ENOG410667J hydrolase EIL75_RS00045 ENOG4105EMF GntR family transcriptional regulator EIL75_RS00050 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 EIL75_RS00055 ENOG4108RTU Aldolase EIL75_RS00065 ENOG4105DJB Major Facilitator Superfamily EIL75_RS00070 ENOG4105BZU Histidine kinase EIL75_RS00075 ENOG4108SV3 Tmao reductase system periplasmic protein tort EIL75_RS00080 ENOG4106WF9 DNA-binding transcriptional regulator TorR EIL75_RS00085 ENOG4105CUW cytochrome C-TYPE protein EIL75_RS00090 ENOG4108EM1 reductase EIL75_RS00100 ENOG4105CA0 peroxidase EIL75_RS00110 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) EIL75_RS00115 ENOG41060IM Heme exporter protein EIL75_RS00120 ENOG4105X3C heme exporter protein EIL75_RS00130 ENOG4105DA4 cytochrome c-type biogenesis protein EIL75_RS00135 ENOG4107QX9 Thiol disulfide interChange protein EIL75_RS00140 ENOG4105KWW Biogenesis protein EIL75_RS00145 ENOG4105D99 atp gtp-binding protein EIL75_RS00150 ENOG4105R2A (LipO)protein EIL75_RS00160 ENOG4108SHS Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent (By similarity) EIL75_RS00170 ENOG4105VG5 Membrane EIL75_RS00175 ENOG4105JP4 Inner membrane protein yidG EIL75_RS00180 ENOG4105J13 transcriptional regulator EIL75_RS00195 ENOG4105W8I Transcriptional regulator EIL75_RS00205 ENOG4105E5M Multidrug resistance protein D EIL75_RS00230 ENOG4105C7K acetolactate synthase EIL75_RS00235 ENOG4105M71 acetolactate synthase 1 regulatory subunit EIL75_RS00240 ENOG4107FB0 transcriptional regulator DeoR family EIL75_RS00250 ENOG4105EDR glucose galactose transporter EIL75_RS00260 ENOG4108KX4 response regulator EIL75_RS00265 ENOG4105BZU Histidine kinase EIL75_RS00270 ENOG4105CXY transporter EIL75_RS00275 ENOG4105CXY transporter EIL75_RS00280 ENOG4108SAJ Protein of unknown function (DUF1198) EIL75_RS00295 ENOG41090UW PTS System EIL75_RS00300 ENOG4105DT3 PTS system, galactitol-specific IIc component EIL75_RS00310 ENOG4105D2N Aldolase EIL75_RS00335 ENOG4105CS2 ec 3.2.1.21 EIL75_RS00340 ENOG4105T8A Uncharacterized protein YicS EIL75_RS00355 ENOG4105DAS pts system EIL75_RS00360 ENOG4105ETZ PTS System EIL75_RS00365 ENOG4105F3R pts system mannose fructose sorbose family iid EIL75_RS00380 ENOG4105DNE Transposase EIL75_RS00385 ENOG4108UZ3 Transporter EIL75_RS00395 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic EIL75_RS00410 ENOG4105CHJ isochorismatase hydrolase EIL75_RS00430 ENOG4105TNG K13735 adhesin invasin EIL75_RS00445 ENOG4108TC1 Transcriptional regulator EIL75_RS00450 ENOG4105FV3 EIL75_RS00460 ENOG4105ISV protein with bipartite regulator domain EIL75_RS00495 ENOG4105CT4 transporter EIL75_RS00500 ENOG4105CJQ hydrolase, family 31 EIL75_RS00505 ENOG4105JV1 AsmA family EIL75_RS00510 ENOG4105C2W permease EIL75_RS00515 ENOG4105D6U Sodium Glutamate Symporter EIL75_RS00525 ENOG4105CB5 ATP-dependent DNA helicase recG EIL75_RS00530 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase EIL75_RS00535 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EIL75_RS00555 ENOG4105EN6 Membrane EIL75_RS00610 ENOG4105DSJ YicC domain protein EIL75_RS00615 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) EIL75_RS00635 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EIL75_RS00665 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase EIL75_RS00670 ENOG4105DKP glycosyl transferase, family 9 EIL75_RS00675 ENOG4107RJ7 Glycosyl transferase (Group 1 EIL75_RS00680 ENOG4107543 (lipo)polysaccharide EIL75_RS00690 ENOG4107XU6 Glycosyl transferase (Group 1 EIL75_RS00695 ENOG4106AH0 Glycosyl Transferase EIL75_RS00700 ENOG4105X1N Glycosyl transferase family 8 EIL75_RS00705 ENOG4108PDR lipopolysaccharide core biosynthesis protein EIL75_RS00710 ENOG4108QD8 lipopolysaccharide core biosynthesis protein EIL75_RS00715 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase EIL75_RS00720 ENOG4108FRV O-antigen ligase EIL75_RS00725 ENOG4105D16 lipopolysaccharide heptosyltransferase i EIL75_RS00730 ENOG4105XA0 heptosyltransferase ii EIL75_RS00740 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) EIL75_RS00750 ENOG4105K64 Glycosyl transferase, family 2 EIL75_RS00755 ENOG4105PXI polysaccharide deacetylase EIL75_RS00760 ENOG41063SB peptidase EIL75_RS00770 ENOG4107YZP Rhodanese domain protein EIL75_RS00775 ENOG4105VW4 glutaredoxin 3 EIL75_RS00780 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) EIL75_RS00785 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase EIL75_RS00790 ENOG4105D7W serine acetyltransferase EIL75_RS00795 ENOG4105DJB Major Facilitator Superfamily EIL75_RS00800 ENOG4105DIA mandelate racemase muconate lactonizing EIL75_RS00805 ENOG4105ETE Transcriptional regulator (LacI family EIL75_RS00810 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EIL75_RS00820 ENOG41073TP transcriptional regulator EIL75_RS00825 ENOG4105DAA L-lactate EIL75_RS00830 ENOG4105EUR Domain-Containing protein EIL75_RS00835 ENOG4108WY4 inner membrane lipoprotein EIL75_RS00840 ENOG4108YYI Protein of unknown function (DUF2810) EIL75_RS00850 ENOG4105E61 Mannitol repressor protein EIL75_RS00860 ENOG4105CTS PTS system mannitol-specific EIL75_RS00865 ENOG4108U78 Glutathione S-transferase EIL75_RS00875 ENOG4105EM7 Selenocysteine-specific translation elongation factor EIL75_RS00880 ENOG41066F8 ROK family EIL75_RS00885 ENOG4105C26 Dehydrogenase EIL75_RS00900 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase EIL75_RS00905 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase EIL75_RS00910 ENOG4105H6Q decarboxylase EIL75_RS00915 ENOG4105CMG Carbohydrate kinase EIL75_RS00920 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit EIL75_RS00925 ENOG4105CG6 trap dicarboxylate transporter dctm subunit EIL75_RS00930 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter EIL75_RS00935 ENOG4108M5W EIL75_RS00940 ENOG4108R66 Conserved Protein EIL75_RS00950 ENOG4105J4Q Transcriptional regulator EIL75_RS00955 ENOG4108XIB electron transport protein ysaA EIL75_RS00960 ENOG4105JKW Valine--pyruvate aminotransferase EIL75_RS00965 ENOG4107T9C Alpha amylase catalytic region EIL75_RS00970 ENOG4108UR8 BAX protein EIL75_RS00975 ENOG4105T16 Transcriptional regulator (AraC family) EIL75_RS00990 ENOG4105CMG Carbohydrate kinase EIL75_RS00995 ENOG410688U Inner membrane protein yiaB EIL75_RS01000 ENOG4105MEV Acyl-transferase EIL75_RS01010 ENOG4105RGS lipoprotein ysaB EIL75_RS01035 ENOG4105CA9 Pyruvate kinase EIL75_RS01045 ENOG4105CPF Cell wall formation (By similarity) EIL75_RS01050 ENOG4105D1Z hydroxypyruvate reductase EIL75_RS01055 ENOG4105CSP Major Facilitator Superfamily EIL75_RS01060 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) EIL75_RS01085 ENOG4105MVF Transcriptional regulator EIL75_RS01090 ENOG4106JH6 (LipO)protein EIL75_RS01100 ENOG4108ZG0 Ompa motb domain protein EIL75_RS01105 ENOG4107QY8 reductase EIL75_RS01110 ENOG4105HNP -acetyltransferase EIL75_RS01115 ENOG4108R3E Dna-3-methyladenine glycosylase i EIL75_RS01120 ENOG4105EAX Putative lipase EIL75_RS01125 ENOG4106EAR Fimbrial protein EIL75_RS01130 ENOG4108VCD Chaperone EIL75_RS01135 ENOG4105CW0 outer membrane usher protein EIL75_RS01140 ENOG4105MHR Fimbrial protein EIL75_RS01145 ENOG4106UCC Fimbrial protein EIL75_RS01150 ENOG4105DIJ Phosphoethanolamine transferase EIL75_RS01185 ENOG4105DEF Extracellular solute-binding protein, family 5 EIL75_RS01190 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EIL75_RS01195 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EIL75_RS01200 ENOG4105C3U ABC transporter EIL75_RS01205 ENOG4108JQ7 (ABC) transporter EIL75_RS01210 ENOG4105C44 Serine transporter EIL75_RS01225 ENOG4105D1V cellulose synthase operon protein YhjU EIL75_RS01230 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT EIL75_RS01240 ENOG410661M cytoplasmic protein EIL75_RS01245 ENOG4105UTS cellulose synthase operon protein YhjQ EIL75_RS01250 ENOG4107QZ7 Cellulose synthase catalytic subunit EIL75_RS01255 ENOG4107EEX Cellulose synthase regulator protein EIL75_RS01260 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) EIL75_RS01265 ENOG4105EJG cellulose synthase EIL75_RS01275 ENOG4105BZU Histidine kinase EIL75_RS01285 ENOG4105CS0 peptidase EIL75_RS01290 ENOG4107SS6 2-dehydro-3-deoxygluconokinase EIL75_RS01295 ENOG4105CMB EAL domain-containing protein EIL75_RS01300 ENOG41066T0 asmA family EIL75_RS01305 ENOG4105CSH Transporter EIL75_RS01310 ENOG4107H3J ribonuclease EIL75_RS01315 ENOG4105CBN LysR family transcriptional regulator EIL75_RS01320 ENOG4106S2D Transcriptional regulator EIL75_RS01340 ENOG4105FDP GntR family transcriptional regulator EIL75_RS01345 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine EIL75_RS01350 ENOG4108KPW sugar kinase EIL75_RS01355 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter EIL75_RS01370 ENOG4105DC8 reductase EIL75_RS01375 ENOG4105D6S protein involved in catabolism of external DNA EIL75_RS01385 ENOG410657R replicase EC 2.7 EIL75_RS01390 ENOG4105DGW oligopeptidase A EIL75_RS01400 ENOG4105DUX Transporter EIL75_RS01405 ENOG4108M6U Universal stress protein A EIL75_RS01415 ENOG4105CJ3 phosphate transporter EIL75_RS01420 ENOG4105CBX hi0933 family EIL75_RS01425 ENOG4105D0S secretion protein (HlyD EIL75_RS01430 ENOG4105CJ1 ABC, transporter EIL75_RS01435 ENOG4105CMI transporter EIL75_RS01445 ENOG4107YAK holo-(acyl carrier protein) synthase 2 EIL75_RS01450 ENOG4105DSF transport protein EIL75_RS01460 ENOG4108W1V Lipoprotein EIL75_RS01465 ENOG4105EX9 Membrane EIL75_RS01475 ENOG4105C8Q Methyl-accepting chemotaxis EIL75_RS01485 ENOG4107FS9 Membrane EIL75_RS01495 ENOG4105MG3 Membrane EIL75_RS01500 ENOG4106H78 methyltransferase EIL75_RS01505 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EIL75_RS01510 ENOG4105CAK Cell division ATP-binding protein ftsE EIL75_RS01515 ENOG4105CRP Part of the ABC transporter FtsEX involved in EIL75_RS01525 ENOG4105CP9 extracellular ligand-binding receptor EIL75_RS01530 ENOG4105U59 -acetyltransferase EIL75_RS01535 ENOG4105CP9 extracellular ligand-binding receptor EIL75_RS01540 ENOG4105C32 Amino acid ABC transporter (Permease) EIL75_RS01545 ENOG4105CF8 branched-chain amino acid ABC transporter, permease EIL75_RS01550 ENOG4105C0Z ABC transporter EIL75_RS01555 ENOG4108IV0 ABC, transporter EIL75_RS01560 ENOG41060M8 Pfam:PhdYeFM EIL75_RS01570 ENOG4105BZ7 extracellular solute-binding protein family 1 EIL75_RS01575 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component EIL75_RS01585 ENOG4108IJ9 (ABC) transporter EIL75_RS01590 ENOG4107T6V glycerophosphoryl diester phosphodiesterase EIL75_RS01595 ENOG4105WC8 Conserved Protein EIL75_RS01600 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) EIL75_RS01605 ENOG41080QX K07048 phosphotriesterase-related protein EIL75_RS01620 ENOG4108RVA ribokinase EIL75_RS01625 ENOG4105WCN acetyltransferase EIL75_RS01630 ENOG4105D9R oxidoreductase EIL75_RS01635 ENOG4105C2I pirin domain protein EIL75_RS01640 ENOG4105DIQ Transcriptional regulator EIL75_RS01645 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EIL75_RS01650 ENOG4105C6Z Gluconate EIL75_RS01660 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EIL75_RS01665 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) EIL75_RS01685 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) EIL75_RS01690 ENOG4107HP6 Transcriptional regulator EIL75_RS01695 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EIL75_RS01700 ENOG4105C01 Dihydroxy-acid dehydratase EIL75_RS01710 ENOG4105DCT glycerol dehydrogenase EIL75_RS01725 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EIL75_RS01740 ENOG4105E98 transcriptional regulator DeoR family EIL75_RS01745 ENOG4105CYB regulatoR EIL75_RS01755 ENOG4105E0Y RtcB Protein EIL75_RS01775 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) EIL75_RS01780 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) EIL75_RS01785 ENOG4105C6Z Gluconate EIL75_RS01795 ENOG4105MJ2 Competence protein EIL75_RS01805 ENOG4105DNE Transposase EIL75_RS01820 ENOG4105XFK Ferrous iron transport protein A EIL75_RS01825 ENOG4105BZM domain protein EIL75_RS01830 ENOG4108RRZ Transcription elongation factor GreB EIL75_RS01840 ENOG4105E0F Histidine kinase EIL75_RS01850 ENOG4108MAJ Membrane EIL75_RS01860 ENOG4105VEJ Heat shock protein EIL75_RS01865 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 EIL75_RS01875 ENOG4107RK2 ADP-ribose diphosphatase NudE EIL75_RS01880 ENOG4108JQC penicillin-binding protein 1A EIL75_RS01885 ENOG4108U1Q Pilus assembly protein EIL75_RS01890 ENOG41065NF Fimbrial assembly family protein EIL75_RS01895 ENOG4105XPX DNA utilization protein HofO EIL75_RS01900 ENOG4105ITY Required for the use of extracellular DNA as a nutrient EIL75_RS01905 ENOG4105E4G Type IV pilus EIL75_RS01925 ENOG4105EGB membrane protein DamX EIL75_RS01930 ENOG4105DFE Dna adenine methylase EIL75_RS01935 ENOG4105DJV ribulose-phosphate 3-epimerase EIL75_RS01945 ENOG4105C31 Tryptophanyl-tRNA synthetase EIL75_RS01950 ENOG4105VYH EIL75_RS01955 ENOG4107EF2 surface-exposed virulence protein EIL75_RS01965 ENOG4107V9H nitrite transporter EIL75_RS01970 ENOG4105WZK nitrite reductase NADPH small subunit EIL75_RS01975 ENOG4107QZF nitrite reductase NADPH large subunit EIL75_RS01985 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EIL75_RS01990 ENOG4106195 uncharacterized protein yhfG EIL75_RS01995 ENOG4105MZU cell filamentation protein EIL75_RS02000 ENOG4105DDQ anthranilate synthase EIL75_RS02005 ENOG4105C8Y Acetylornithine aminotransferase EIL75_RS02010 ENOG410613R integral membrane protein, YccS YhfK family EIL75_RS02015 ENOG4107RYR Transcriptional regulator, Crp Fnr family EIL75_RS02020 ENOG4108UKZ OsmC family EIL75_RS02025 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) EIL75_RS02035 ENOG4105DNZ Alpha Beta Hydrolase EIL75_RS02040 ENOG4105N0V mono-oxygenase ydhR EIL75_RS02045 ENOG4108K70 Transcriptional regulator EIL75_RS02050 ENOG4105C5H ABC transporter EIL75_RS02065 ENOG4105VKU nucleicacid-binding protein EIL75_RS02070 ENOG4108YZY peptidylprolyl cis-trans isomerase EIL75_RS02075 ENOG4105VRX Protein slyX homolog EIL75_RS02080 ENOG4108V1T peptidylprolyl cis-trans isomerase EIL75_RS02085 ENOG4105WWK YheO domain protein EIL75_RS02100 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) EIL75_RS02120 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) EIL75_RS02125 ENOG4105W53 bacterioferritin-associated ferredoxin EIL75_RS02130 ENOG4108UQY Iron-storage protein EIL75_RS02135 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) EIL75_RS02165 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) EIL75_RS02185 ENOG41083MP 50s ribosomal protein l29 EIL75_RS02190 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal EIL75_RS02225 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) EIL75_RS02235 ENOG4105VPB 50S ribosomal protein L30 EIL75_RS02245 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EIL75_RS02250 ENOG41067V7 50S ribosomal protein L36 EIL75_RS02265 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) EIL75_RS02280 ENOG4105VTS DnaJ-like, subfamily C EIL75_RS02285 ENOG4105W1Y Transcriptional regulator EIL75_RS02290 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system EIL75_RS02295 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) EIL75_RS02300 ENOG4105C1A potassium transporter peripheral membrane EIL75_RS02320 ENOG4105C79 DNA protecting protein DprA EIL75_RS02330 ENOG4108WI1 Dna topoisomerase EIL75_RS02345 ENOG4105SG3 Protein of unknown function (DUF1488) EIL75_RS02350 ENOG4108Z0R Transferase EIL75_RS02385 ENOG4105XCM membrane LIPOPROTEIN EIL75_RS02390 ENOG4105BZS acriflavin resistance protein EIL75_RS02395 ENOG4105C1P efflux transporter, rnd family, mfp subunit EIL75_RS02400 ENOG4108XG4 DNA-binding transcriptional regulator EIL75_RS02405 ENOG4105BZU Histidine kinase EIL75_RS02410 ENOG41061ME transport protein EIL75_RS02415 ENOG4105CEC DNA methylase N-4 N-6 EIL75_RS02425 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EIL75_RS02440 ENOG4108IA2 Sodium pantothenate symporter EIL75_RS02445 ENOG4105RG0 Membrane EIL75_RS02450 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EIL75_RS02455 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein EIL75_RS02470 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family EIL75_RS02475 ENOG41062P1 Diguanylate cyclase phosphodiesterase EIL75_RS02490 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) EIL75_RS02495 ENOG4105VQ7 Rod shape-determining protein MreD EIL75_RS02500 ENOG4108Z03 MAF-like protein EIL75_RS02505 ENOG4105C03 ribonuclease EIL75_RS02510 ENOG4105QD6 exported protein EIL75_RS02515 ENOG4105D1U peptidase U62 modulator of DNA gyrase EIL75_RS02520 ENOG4105CR8 Transcriptional regulator EIL75_RS02525 ENOG4105ZQC membrane protein AaeX EIL75_RS02540 ENOG4105UNR (Barnase) inhibitor EIL75_RS02545 ENOG4105RID UPF0379 protein yhcN EIL75_RS02550 ENOG4105RID UPF0379 protein yhcN EIL75_RS02575 ENOG4105C8P )-transporter EIL75_RS02580 ENOG4106DSS Tartrate dehydratase subunit alpha EIL75_RS02585 ENOG4107GFK fumarate EIL75_RS02595 ENOG4107QSA Oxaloacetate decarboxylase EIL75_RS02600 ENOG4105D9Q decarboxylase (Beta subunit) EIL75_RS02615 ENOG4105C0H protease EIL75_RS02620 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III EIL75_RS02625 ENOG4105D6Z AFG1 family ATPase EIL75_RS02640 ENOG4107MKT Stringent starvation protein a EIL75_RS02645 ENOG4105KB2 stringent starvation protein b EIL75_RS02675 ENOG4108R66 Conserved Protein EIL75_RS02680 ENOG4105DZC cytosine deaminase EIL75_RS02685 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin EIL75_RS02690 ENOG4105DFS Conserved Protein EIL75_RS02695 ENOG4105BZ8 glutamate synthase EIL75_RS02700 ENOG4105CBC glutamate synthase EIL75_RS02705 ENOG4105N5T Radical SAM Protein EIL75_RS02710 ENOG4105BZU Histidine kinase EIL75_RS02715 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain EIL75_RS02725 ENOG4108NIH transferase activity, transferring phosphorus-containing groups EIL75_RS02735 ENOG41080Z8 PHOSPHOCARRIER protein EIL75_RS02745 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN EIL75_RS02750 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA EIL75_RS02755 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EIL75_RS02760 ENOG4108IUZ ABC transporter EIL75_RS02765 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA EIL75_RS02770 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) EIL75_RS02775 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase EIL75_RS02780 ENOG4105C2X Arabinose 5-phosphate isomerase EIL75_RS02785 ENOG4105FEU K -dependent Na -Ca exchanger EIL75_RS02790 ENOG4105DHJ ABC, transporter EIL75_RS02795 ENOG4105CY3 ABC transporter, permease EIL75_RS02800 ENOG4107PE3 Mammalian cell entry related domain protein EIL75_RS02805 ENOG4105E3I toluene tolerance EIL75_RS02810 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane EIL75_RS02815 ENOG4105VFK BolA family EIL75_RS02825 ENOG4105HVQ Regulatory factor of maltose metabolism EIL75_RS02830 ENOG4105EAH synthase EIL75_RS02840 ENOG4105K46 50S ribosomal protein l27 EIL75_RS02845 ENOG4105QYV Membrane EIL75_RS02855 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase EIL75_RS02860 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) EIL75_RS02865 ENOG4105HBR Rna-binding protein EIL75_RS02875 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EIL75_RS02880 ENOG4105EEI dihydropteroate synthase EIL75_RS02890 ENOG4105NTZ Preprotein translocase subunit SecG EIL75_RS02915 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) EIL75_RS02920 ENOG4105CHV Transcription elongation factor NusA EIL75_RS02960 ENOG4105C1J atp-dependent rna helicase EIL75_RS02965 ENOG4105CIC tryptophan-specific transport protein EIL75_RS02970 ENOG4105DEN Luciferase family EIL75_RS02990 ENOG4108YYD acetyltransferase EIL75_RS03005 ENOG4107R7Y intracellular protease Pfpi family EIL75_RS03010 ENOG4105K4T epimerase EIL75_RS03015 ENOG4105W4M Transport-associated protein EIL75_RS03030 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) EIL75_RS03035 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EIL75_RS03045 ENOG4107WTH Galactitol-1-phosphate dehydrogenase EIL75_RS03050 ENOG4105DT3 PTS system, galactitol-specific IIc component EIL75_RS03055 ENOG41090UW PTS System EIL75_RS03060 ENOG41082GB PTS system galactitol-specific transporter subunit IIA EIL75_RS03075 ENOG4105CTX dehydratase EIL75_RS03085 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EIL75_RS03090 ENOG4105BZW Glycerate kinase EIL75_RS03105 ENOG410811B TRANSCRIPTIONal EIL75_RS03110 ENOG4105C7B Threonine dehydratase EIL75_RS03125 ENOG4105C6N Formate acetyltransferase EIL75_RS03130 ENOG4105EJQ L-serine dehydratase EIL75_RS03135 ENOG4105C44 Serine transporter EIL75_RS03145 ENOG4106D80 Uncharacterized protein YhaL EIL75_RS03150 ENOG4108CNN domain protein EIL75_RS03155 ENOG4105CWB LysR family transcriptional Regulator EIL75_RS03160 ENOG4105KAF membrAne EIL75_RS03165 ENOG4105CHF Glutathione S-transferase EIL75_RS03170 ENOG4108VBZ doxx family EIL75_RS03175 ENOG4105YJD EIL75_RS03180 ENOG41090KG Inner membrane protein YqjE EIL75_RS03185 ENOG4105NE1 Conserved Protein EIL75_RS03190 ENOG4105WAY exported protein EIL75_RS03200 ENOG4106W5V Membrane EIL75_RS03210 ENOG4105DU1 integral membrane protein, terc EIL75_RS03215 ENOG4105EE0 oxidoreductase EIL75_RS03220 ENOG4108UB4 uncharacterized protein ygjQ EIL75_RS03225 ENOG4108VKG metal-dependent hydrolase EIL75_RS03235 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EIL75_RS03245 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor EIL75_RS03250 ENOG4105C8Q Methyl-accepting chemotaxis EIL75_RS03255 ENOG4105NTW Transcriptional regulator EIL75_RS03260 ENOG4105Q26 Siderophore-interacting protein EIL75_RS03270 ENOG4108VCA G U mismatch-specific DNA glycosylase EIL75_RS03275 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EIL75_RS03280 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EIL75_RS03305 ENOG4107ZVW dihydroneopterin aldolase EIL75_RS03320 ENOG4106MWK domain protein EIL75_RS03325 ENOG4105I7R Adenylate cyclase EIL75_RS03345 ENOG4107S78 Band 7 protein EIL75_RS03350 ENOG4105PV3 Inner membrane protein yqiJ EIL75_RS03360 ENOG4105W0Z cytoplasmic protein EIL75_RS03370 ENOG4108PSN Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity) EIL75_RS03380 ENOG4108MR7 Arylsulfotransferase EIL75_RS03390 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EIL75_RS03395 ENOG4106032 Glutathionylspermidine synthase EIL75_RS03400 ENOG4105F1G UPF0441 protein EIL75_RS03410 ENOG41087AY ADP-Ribose pyrophosphatase EIL75_RS03415 ENOG4108SX3 cytoplasmic protein EIL75_RS03420 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EIL75_RS03425 ENOG4105IPS esterase EIL75_RS03430 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EIL75_RS03435 ENOG4105VRH Antibiotic biosynthesis monooxygenase EIL75_RS03440 ENOG4105NF4 modulator of drug activity EIL75_RS03445 ENOG4105DHQ Histidine kinase EIL75_RS03450 ENOG4105XJC Two component transcriptional regulator (Winged helix family EIL75_RS03455 ENOG4105H4F exported protein EIL75_RS03460 ENOG4105F4I Transcriptional regulator EIL75_RS03465 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EIL75_RS03470 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase EIL75_RS03475 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) EIL75_RS03480 ENOG4105CG6 trap dicarboxylate transporter dctm subunit EIL75_RS03490 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit EIL75_RS03495 ENOG4105CCT upf0313 protein EIL75_RS03515 ENOG4107QPK )-transporter EIL75_RS03520 ENOG4105CV8 reductase EIL75_RS03525 ENOG4108I6A alcohol dehydrogenase EIL75_RS03530 ENOG4105CF7 AraC family transcriptional regulator EIL75_RS03535 ENOG4108K81 inner membrane protein YghB EIL75_RS03540 ENOG4105C28 cystathionine EIL75_RS03545 ENOG4105CWK Biopolymer transport protein, ExbB EIL75_RS03550 ENOG4108ZZF transport protein (ExbD) EIL75_RS03555 ENOG4105CYX Short-chain dehydrogenase reductase Sdr EIL75_RS03580 ENOG4105C8Q Methyl-accepting chemotaxis EIL75_RS03585 ENOG410900S Protein of unknown function (DUF2623) EIL75_RS03590 ENOG4105E3S small subunit EIL75_RS03595 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein EIL75_RS03600 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit EIL75_RS03605 ENOG4105DPX Hydrogenase, large subunit EIL75_RS03610 ENOG4108USZ hydrogenase EIL75_RS03615 ENOG4108WGS hydrogenase 2-specific chaperone EIL75_RS03620 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) EIL75_RS03625 ENOG41082MF Hydrogenase assembly chaperone hypC hupF EIL75_RS03630 ENOG4105S10 periplasmic binding protein EIL75_RS03635 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein EIL75_RS03640 ENOG4105CYM Glutathione S-transferase EIL75_RS03645 ENOG4106032 Glutathionylspermidine synthase EIL75_RS03660 ENOG4105DEI Mannitol dehydrogenase EIL75_RS03670 ENOG4105DPW Major facilitator superfamily MFS_1 EIL75_RS03695 ENOG4105C26 Dehydrogenase EIL75_RS03700 ENOG4105CJP fad dependent oxidoreductase EIL75_RS03710 ENOG4105CUB amino acid EIL75_RS03720 ENOG4108UAJ Transcriptional regulator EIL75_RS03810 ENOG4108UQV Membrane EIL75_RS03815 ENOG4105CXN decarboxylase EIL75_RS03820 ENOG4105EAA nucleoside EIL75_RS03830 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) EIL75_RS03835 ENOG4105CEN a g-specific adenine glycosylase EIL75_RS03845 ENOG41090ED Protein with unknown function (DUF469) EIL75_RS03850 ENOG4105K33 Periplasmic Protein EIL75_RS03855 ENOG4105HDK L-asparaginase EIL75_RS03860 ENOG4106MH3 alpha helix chain EIL75_RS03865 ENOG4105CSA Coproporphyrinogen iii oxidase EIL75_RS03880 ENOG4108VIA integral membrane protein EIL75_RS03885 ENOG4105DFA alanine racemase domain protein EIL75_RS03890 ENOG4105CZX twitching motility protein EIL75_RS03910 ENOG4105D7Z glutathione synthase EIL75_RS03915 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EIL75_RS03920 ENOG4105RWS endonuclease I EIL75_RS03930 ENOG4107QNK )-transporter EIL75_RS03955 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) EIL75_RS03965 ENOG4107YCY Transcriptional regulator EIL75_RS03975 ENOG4105DEI Mannitol dehydrogenase EIL75_RS03980 ENOG4105CPQ Dehydrogenase EIL75_RS03985 ENOG4105DG4 malate L-lactate dehydrogenase EIL75_RS03990 ENOG4108R66 Conserved Protein EIL75_RS03995 ENOG4108MXF Alpha Beta Hydrolase EIL75_RS04010 ENOG4108K0D peptidase, M48 EIL75_RS04015 ENOG4105CV1 Transketolase (EC 2.2.1.1) EIL75_RS04020 ENOG4108JJB ABC transporter EIL75_RS04025 ENOG4108JJB ABC transporter EIL75_RS04055 ENOG4105BZA Phosphoglycerate kinase EIL75_RS04060 ENOG4105D2N Aldolase EIL75_RS04065 ENOG4105D64 Mechanosensitive ion channel EIL75_RS04075 ENOG4105MPN Membrane EIL75_RS04095 ENOG4108JQ1 Dehydrogenase EIL75_RS04100 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EIL75_RS04120 ENOG4107RAQ aminopeptidase EIL75_RS04125 ENOG4105D0A hydroxylase EIL75_RS04130 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EIL75_RS04160 ENOG4105CS2 ec 3.2.1.21 EIL75_RS04170 ENOG4108UT2 hemolysin iii EIL75_RS04190 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB EIL75_RS04195 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) EIL75_RS04200 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EIL75_RS04205 ENOG4105T95 Thiol disulfide interChange protein EIL75_RS04210 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EIL75_RS04235 ENOG4108K5P (LipO)protein EIL75_RS04260 ENOG4108T1M outer membrane protein x EIL75_RS04280 ENOG4106P2F Pfam:Pili_assembly_C EIL75_RS04310 ENOG4108MHD transport protein EIL75_RS04320 ENOG4105C5Q Transcriptional regulator EIL75_RS04325 ENOG4105CHU acetyl-coa acetyltransferase EIL75_RS04340 ENOG4105CHR reductase EIL75_RS04345 ENOG4107QNK )-transporter EIL75_RS04355 ENOG4105RQF LysR family Transcriptional regulator EIL75_RS04365 ENOG4105DDV Transcriptional regulator (LacI family EIL75_RS04395 ENOG4105CPC Aldo Keto reductase EIL75_RS04400 ENOG4105SUV lipoprotein YgdR EIL75_RS04405 ENOG4105EE5 Membrane protein terC EIL75_RS04420 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase EIL75_RS04440 ENOG4105IPU prepilin peptidase dependent protein A EIL75_RS04445 ENOG4105JCS prepilin peptidase dependent protein EIL75_RS04450 ENOG4105SEN Protein of unknown function (DUF2509) EIL75_RS04455 ENOG4105RVB Prepilin peptidase dependent protein c EIL75_RS04460 ENOG4105DSY exodeoxyribonuclease V, gamma EIL75_RS04465 ENOG4107QXK peptidase EIL75_RS04470 ENOG4107QKA exodeoxyribonuclease V beta EIL75_RS04475 ENOG4107QYX exodeoxyribonuclease v alpha EIL75_RS04480 ENOG4108EKC n-acetylglutamate synthase EIL75_RS04485 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase EIL75_RS04500 ENOG4105CA3 membrane-bound lytic murein transglycosylase EIL75_RS04505 ENOG4105CUZ uba thif-type nad fad binding protein EIL75_RS04510 ENOG4105FR1 rard protein EIL75_RS04515 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) EIL75_RS04520 ENOG4105C9B Cysteine desulfurase EIL75_RS04525 ENOG4105M5B (LipO)protein EIL75_RS04530 ENOG4105ETT transcriptional Regulator, LysR family EIL75_RS04535 ENOG4105M08 Membrane EIL75_RS04545 ENOG4107EDW L-fucose operon activator EIL75_RS04555 ENOG4105CMG Carbohydrate kinase EIL75_RS04565 ENOG4105EDR glucose galactose transporter EIL75_RS04570 ENOG4107W7X Aldolase EIL75_RS04575 ENOG4105C0A alcohol dehydrogenase EIL75_RS04590 ENOG4105EJQ L-serine dehydratase EIL75_RS04595 ENOG4105C44 Serine transporter EIL75_RS04600 ENOG4105EWT decarboxylase family EIL75_RS04620 ENOG4105WP7 tRNA pseudouridine synthase C EIL75_RS04625 ENOG4105DR9 pseudouridine synthase EIL75_RS04630 ENOG4105QDK Flavodoxin EIL75_RS04640 ENOG4105DJB Major Facilitator Superfamily EIL75_RS04645 ENOG4105EQX glucarate dehydratase EIL75_RS04650 ENOG4105EQX glucarate dehydratase EIL75_RS04655 ENOG4105BZW Glycerate kinase EIL75_RS04660 ENOG4105BZU Histidine kinase EIL75_RS04665 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) EIL75_RS04670 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EIL75_RS04690 ENOG4105NEV Fimbrial EIL75_RS04695 ENOG4108FZ9 Chaperone EIL75_RS04700 ENOG4106PG1 outer membrane usher protein EIL75_RS04710 ENOG4105DXN mazG family EIL75_RS04720 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) EIL75_RS04725 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EIL75_RS04730 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) EIL75_RS04735 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase EIL75_RS04745 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) EIL75_RS04755 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) EIL75_RS04765 ENOG4105DTT CRISPR-associated helicase, cas3 EIL75_RS04780 ENOG41060M0 Crispr-associated protein, cse4 family EIL75_RS04785 ENOG4108VWQ crispr-associated protein EIL75_RS04795 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) EIL75_RS04800 ENOG4105PWE CRISPR-associated protein cas2 EIL75_RS04805 ENOG4108MXK alkaline phosphatase isozyme conversion EIL75_RS04825 ENOG4105N0Z inner membrane protein ygbE EIL75_RS04860 ENOG4108K5P (LipO)protein EIL75_RS04870 ENOG4105KZM cytoplasmic protein EIL75_RS04875 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) EIL75_RS04880 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase EIL75_RS04890 ENOG4105MVE transcriptional regulator EIL75_RS04900 ENOG4105G63 Type III effector Hrp-dependent EIL75_RS04910 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EIL75_RS04915 ENOG4105EXW epimerase dehydratase EIL75_RS04920 ENOG4105C6Z Gluconate EIL75_RS04925 ENOG4105JQN Transcriptional regulator EIL75_RS04930 ENOG4105C0R drug resistance transporter emrb qaca subfamily EIL75_RS04965 ENOG4105MEW serine threonine protein phosphatase EIL75_RS05010 ENOG41090HZ type iii secretion EIL75_RS05020 ENOG4108N8R Invasion protein EIL75_RS05025 ENOG4108HR8 type iii secretion EIL75_RS05030 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone EIL75_RS05035 ENOG4108JIR Flagellum-specific ATP synthase EIL75_RS05040 ENOG41077MC Secretory protein (Associated with virulence) EIL75_RS05045 ENOG41078G4 surface presentation of EIL75_RS05050 ENOG4105T85 surface presentation of antigens protein EIL75_RS05055 ENOG41075IY surface presentation of antigens protein SpaP EIL75_RS05060 ENOG4105U07 type iii secretion EIL75_RS05065 ENOG4108TN6 type iii secretion EIL75_RS05070 ENOG4108M6W surface presentation of antigens protein SpaS EIL75_RS05080 ENOG4106H1J Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE EIL75_RS05090 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC EIL75_RS05100 ENOG41079WB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) EIL75_RS05115 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear EIL75_RS05125 ENOG4108YAB Invasion protein EIL75_RS05135 ENOG4108RC9 Type III secretion system protein EIL75_RS05140 ENOG4105Y7Q type iii secretion EIL75_RS05145 ENOG4106BTR EIL75_RS05150 ENOG4108RBT type iii secretion EIL75_RS05185 ENOG4105CC5 ABC transporter EIL75_RS05190 ENOG4105CC5 ABC transporter EIL75_RS05195 ENOG4105DIK (ABC) transporter EIL75_RS05205 ENOG4105VXR cytoplasmic protein EIL75_RS05215 ENOG4105C45 hydrogenase expression formation protein (HypE) EIL75_RS05220 ENOG4105CQS hydrogenase expression formation protein HypD EIL75_RS05225 ENOG41083WG hydrogenase assembly chaperone EIL75_RS05230 ENOG4107RSS Hydrogenase accessory protein HypB EIL75_RS05235 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) EIL75_RS05245 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA EIL75_RS05250 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) EIL75_RS05255 ENOG4107R30 NADH dehydrogenase EIL75_RS05260 ENOG4107TDF Formate hydrogenlyase subunit 4 EIL75_RS05265 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) EIL75_RS05270 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit EIL75_RS05275 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit EIL75_RS05280 ENOG4105I6X formate hydrogenlyase maturation EIL75_RS05285 ENOG4108MG9 hydrogenase 3 maturation protease EIL75_RS05295 ENOG4108RC0 Electron transport protein EIL75_RS05300 ENOG4105C8H hydrogenase maturation protein Hypf EIL75_RS05320 ENOG4105C2X Arabinose 5-phosphate isomerase EIL75_RS05330 ENOG4105J92 DNA-binding transcriptional activator GutM EIL75_RS05335 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase EIL75_RS05340 ENOG4105VI0 Pts system, glucitol sorbitol-specific EIL75_RS05345 ENOG4105DZY Pts system, glucitol sorbitol-specific EIL75_RS05350 ENOG410787A Pts system, glucitol sorbitol-specific EIL75_RS05355 ENOG4105CVE Lytic murein transglycosylase EIL75_RS05365 ENOG4107TH8 cina domain protein EIL75_RS05385 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) EIL75_RS05390 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) EIL75_RS05420 ENOG4107VXZ Hydrolase EIL75_RS05425 ENOG4105W39 Membrane EIL75_RS05445 ENOG4105C0R drug resistance transporter emrb qaca subfamily EIL75_RS05450 ENOG4105CW7 secretion protein, HlyD family EIL75_RS05455 ENOG4105NTK Transcriptional repressor Mpra EIL75_RS05465 ENOG4105GIJ Glycine betaine EIL75_RS05470 ENOG4108HQS Glycine betaine EIL75_RS05475 ENOG4108IJ7 Glycine betaine EIL75_RS05485 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EIL75_RS05490 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EIL75_RS05500 ENOG4105WAZ (Glutaredoxin-like protein) NrdH EIL75_RS05510 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) EIL75_RS05520 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) EIL75_RS05525 ENOG4108WMJ Protein of unknown function (DUF2002) EIL75_RS05530 ENOG4108RNS Exports L-alanine (By similarity) EIL75_RS05540 ENOG4108X73 DNA- binding protein EIL75_RS05550 ENOG4108V62 Rhodanese domain protein EIL75_RS05555 ENOG41080HT Transcriptional regulator, arsr family EIL75_RS05560 ENOG4105VPI YqaE family transport protein EIL75_RS05570 ENOG4109066 lysm domain bon superfamily protein EIL75_RS05575 ENOG4108PVQ transcriptional regulator EIL75_RS05580 ENOG4105C85 amino acid EIL75_RS05585 ENOG4108JPW Aminotransferase EIL75_RS05590 ENOG4105C26 Dehydrogenase EIL75_RS05595 ENOG4105D5U fad dependent oxidoreductase EIL75_RS05625 ENOG4105DHQ Histidine kinase EIL75_RS05645 ENOG4108MJ5 VirK protein EIL75_RS05665 ENOG4107RNH Outer membrane receptor FepA EIL75_RS05670 ENOG4105NIV Esterase EIL75_RS05700 ENOG4105XDF Protein of unknown function (DUF1272) EIL75_RS05710 ENOG4105F9F transposase EIL75_RS05750 ENOG4105BZ1 (ABC) transporter EIL75_RS05770 ENOG4108Z1B Cyclase dehydrase EIL75_RS05780 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EIL75_RS05785 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EIL75_RS05810 ENOG4108JU6 CBS domain protein EIL75_RS05815 ENOG4106KVJ cytochrome C assembly protein EIL75_RS05825 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY EIL75_RS05845 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) EIL75_RS05850 ENOG4108KHX Diguanylate cyclase EIL75_RS05855 ENOG4108WS1 EIL75_RS05860 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EIL75_RS05865 ENOG4105EHE chorismate mutase- prephenate dehydrogenase EIL75_RS05875 ENOG4105CQC Prephenate dehydratase EIL75_RS05885 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EIL75_RS05930 ENOG4105ED4 portal protein EIL75_RS06025 ENOG4108X9F tail fiber protein EIL75_RS06030 ENOG4105UZW Tail fiber assembly protein EIL75_RS06055 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) EIL75_RS06065 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA EIL75_RS06075 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane EIL75_RS06080 ENOG4105C34 Pseudouridine synthase EIL75_RS06085 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EIL75_RS06090 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EIL75_RS06120 ENOG4105CSH Transporter EIL75_RS06125 ENOG4105T42 (LipO)protein EIL75_RS06130 ENOG4105JIM Phosphatidylserine synthase EIL75_RS06135 ENOG4105CD5 CoA-binding domain protein EIL75_RS06140 ENOG4106IUH DTW domain containing protein EIL75_RS06145 ENOG4105K63 Thioredoxin EIL75_RS06150 ENOG4105EIB trna rrna methyltransferase EIL75_RS06160 ENOG4108VKA Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity) EIL75_RS06170 ENOG41090KR LysR family transcriptional Regulator EIL75_RS06175 ENOG4105C1J atp-dependent rna helicase EIL75_RS06185 ENOG4108IYU L-aspartate oxidase EIL75_RS06215 ENOG4105WMJ Positive regulator of sigma E, RseC MucC EIL75_RS06230 ENOG4105C3F Signal peptidase i EIL75_RS06260 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EIL75_RS06265 ENOG4105DND Transcriptional regulator EIL75_RS06275 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) EIL75_RS06280 ENOG4106G6Q Transcriptional regulator EIL75_RS06295 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB EIL75_RS06300 ENOG4108Z6B deaminase EIL75_RS06305 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) EIL75_RS06315 ENOG4108ETH Formylglycinamide ribotide synthetase EIL75_RS06320 ENOG4107WP9 Histidine kinase EIL75_RS06325 ENOG4108SKK alpha helix protein EIL75_RS06330 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EIL75_RS06340 ENOG4105DUX Transporter EIL75_RS06345 ENOG4105CXN decarboxylase EIL75_RS06350 ENOG4105D5Q Arginine ornithine antiporter EIL75_RS06355 ENOG4108M3R transcriptional activator CadC EIL75_RS06360 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EIL75_RS06370 ENOG4105D8G Major Facilitator superfamily EIL75_RS06375 ENOG4108MN2 Stationary phase inducible protein CsiE EIL75_RS06385 ENOG4105D7X high-affinity nickel-transporter EIL75_RS06390 ENOG410810Y Sulfite reductase EIL75_RS06395 ENOG4107SHJ sulfite reductase subunit b EIL75_RS06400 ENOG4105D5B Sulfite reductase, subunit A EIL75_RS06405 ENOG4107XM9 (LipO)protein EIL75_RS06410 ENOG4105ECY inositol monophosphatase EIL75_RS06415 ENOG4105CVS RNA methyltransferase TrmH family, group 1 EIL75_RS06430 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins EIL75_RS06435 ENOG4108Z4V iron-sulfur cluster assembly EIL75_RS06450 ENOG4108ZIT Ferredoxin, 2FE-2S EIL75_RS06455 ENOG4105WVQ Fe-S assembly protein IscX EIL75_RS06465 ENOG4105YYA enhanced serine sensitivity protein SseB EIL75_RS06480 ENOG4105KHC sulfurtransferase EIL75_RS06485 ENOG4105DN3 alpha-2-macroglobulin domain protein EIL75_RS06490 ENOG4108JQB penicillin-binding protein 1C EIL75_RS06495 ENOG4107QY8 reductase EIL75_RS06500 ENOG4105QAX Iron-sulfur EIL75_RS06540 ENOG4105N21 Membrane EIL75_RS06545 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EIL75_RS06555 ENOG4105VPD cellular component movement EIL75_RS06590 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EIL75_RS06615 ENOG41062G3 Protein of unknown function (DUF2633) EIL75_RS06625 ENOG4105BZU Histidine kinase EIL75_RS06630 ENOG4105C9X ppx gppa phosphatase EIL75_RS06635 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) EIL75_RS06640 ENOG4108V3E phosphoribosylglycinamide formyltransferase EIL75_RS06650 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) EIL75_RS06655 ENOG4105C2W permease EIL75_RS06665 ENOG4105K89 arsenate reductase EIL75_RS06670 ENOG4105ERG peptidase m48, ste24p EIL75_RS06675 ENOG4105C02 permease EIL75_RS06680 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR EIL75_RS06685 ENOG4107QQ0 gntp family EIL75_RS06690 ENOG4105BZW Glycerate kinase EIL75_RS06695 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EIL75_RS06700 ENOG4105RH4 Glycine cleavage system transcriptional repressor EIL75_RS06710 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EIL75_RS06720 ENOG4105CGZ zinc metallopeptidase EIL75_RS06725 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) EIL75_RS06740 ENOG4105KUZ arsenate reductase EIL75_RS06750 ENOG4105BZS acriflavin resistance protein EIL75_RS06755 ENOG4105BZU Histidine kinase EIL75_RS06760 ENOG4105BZ8 glutamate synthase EIL75_RS06775 ENOG4108PVD exported protein EIL75_RS06785 ENOG4105CV1 Transketolase (EC 2.2.1.1) EIL75_RS06795 ENOG4105C6K Malic enzyme EIL75_RS06800 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place EIL75_RS06805 ENOG4106S4J ethanolamine utilization protein EutP EIL75_RS06810 ENOG4105NDK ethanolamine utilization protein EIL75_RS06815 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase EIL75_RS06820 ENOG4108IJ2 phosphate acetyltransferase EIL75_RS06825 ENOG4105KNY Microcompartments protein EIL75_RS06830 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml EIL75_RS06835 ENOG4108EKI Dehydrogenase EIL75_RS06840 ENOG4107YMV ethanolamine utilization protein EIL75_RS06845 ENOG4105C0A alcohol dehydrogenase EIL75_RS06850 ENOG4105ENY Ethanolamine utilization protein eutH EIL75_RS06855 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase EIL75_RS06860 ENOG4105CPD ethanolamine ammonia-lyase EIL75_RS06870 ENOG4106D67 ethanolamine utilization protein EIL75_RS06875 ENOG4108X49 Ethanolamine utilization protein EutK EIL75_RS06880 ENOG4108K3Z AraC family transcriptional regulator EIL75_RS06885 ENOG4107H8F EIL75_RS06900 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase EIL75_RS06905 ENOG4108R6G acetyltransferase EIL75_RS06910 ENOG4105QZU Inner membrane protein YfeZ EIL75_RS06915 ENOG4105E7K (LipO)protein EIL75_RS06920 ENOG4105EZR dyp-type peroxidase family protein EIL75_RS06925 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr EIL75_RS06930 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein EIL75_RS06935 ENOG4108I5D sulfate abc transporter EIL75_RS06940 ENOG4105ECW sulfate abc transporter EIL75_RS06945 ENOG4108IJ6 ABC transporter EIL75_RS06950 ENOG4105C6T cysteine synthase EIL75_RS06960 ENOG4105M0Y EIL75_RS06965 ENOG41089BK Glutamine amido-transferase EIL75_RS06970 ENOG4105CSW GntR family transcriptional regulator EIL75_RS06975 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) EIL75_RS06985 ENOG4105C5Y PTS System EIL75_RS06990 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) EIL75_RS07000 ENOG4105C6T cysteine synthase EIL75_RS07020 ENOG4105VRT cytoplasmic protein EIL75_RS07025 ENOG4105DHU Bile acid EIL75_RS07030 ENOG4108M0I Transcriptional regulator EIL75_RS07035 ENOG4108NFH Sugar hydrolase EIL75_RS07040 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) EIL75_RS07045 ENOG4105EAA nucleoside EIL75_RS07055 ENOG4105CN8 Transcriptional regulator EIL75_RS07085 ENOG4105GXM Putative transcription regulator (DUF1323) EIL75_RS07090 ENOG4105HZG regulatoR EIL75_RS07105 ENOG4108KMM Diguanylate cyclase EIL75_RS07110 ENOG4105D9N nucleoside EIL75_RS07120 ENOG4109076 Conserved Protein EIL75_RS07125 ENOG4105CPC Aldo Keto reductase EIL75_RS07130 ENOG4107RA9 decarboxylase EIL75_RS07145 ENOG4105CHM Aminotransferase EIL75_RS07155 ENOG4105D1S lipid A biosynthesis EIL75_RS07160 ENOG4105W9M Membrane EIL75_RS07165 ENOG4105CXY transporter EIL75_RS07175 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC EIL75_RS07185 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta EIL75_RS07190 ENOG4108NC2 Outer membrane protease EIL75_RS07240 ENOG41077V0 CPS-53 (KpLE1) prophage EIL75_RS07260 ENOG4108UUM single-stranded DNA-binding protein EIL75_RS07420 ENOG4105HGD Antitermination protein EIL75_RS07430 ENOG4105KUS lysozyme EIL75_RS07435 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 EIL75_RS07595 ENOG4105DFP Integrase EIL75_RS07605 ENOG4105S64 Formate nitrite transporter EIL75_RS07610 ENOG410903C (LipO)protein EIL75_RS07615 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation EIL75_RS07620 ENOG4105KZW UPF0381 protein EIL75_RS07635 ENOG4108BY2 phosphohistidine phosphatase EIL75_RS07645 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) EIL75_RS07660 ENOG4105EJ9 Membrane EIL75_RS07665 ENOG4108BPE -transporting atpase EIL75_RS07670 ENOG4105MH2 YfcL protein EIL75_RS07675 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) EIL75_RS07680 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EIL75_RS07700 ENOG4105R8V Transcriptional regulator EIL75_RS07715 ENOG4106WZ1 flagella biosynthesis regulator EIL75_RS07725 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EIL75_RS07735 ENOG4105DQR SNARE associated Golgi EIL75_RS07745 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EIL75_RS07750 ENOG4108S3P Sporulation domain protein EIL75_RS07755 ENOG4105E96 Colicin v production protein EIL75_RS07760 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase EIL75_RS07765 ENOG4108JUB Transcriptional regulator EIL75_RS07775 ENOG4105E5D amino acid EIL75_RS07780 ENOG4106M28 alanine racemase domain protein EIL75_RS07790 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase EIL75_RS07800 ENOG4105E89 ABC transporter EIL75_RS07805 ENOG4105E89 ABC transporter EIL75_RS07810 ENOG4105DSP amino acid AbC transporter EIL75_RS07815 ENOG4106YG3 ABC transporter EIL75_RS07820 ENOG4108JEH abc transporter atp-binding protein EIL75_RS07825 ENOG4105ECP epimerase EIL75_RS07830 ENOG4105CYM Glutathione S-transferase EIL75_RS07835 ENOG4108SHQ Glutathione S-transferase EIL75_RS07840 ENOG4108RE9 Phosphodiesterase EIL75_RS07845 ENOG4105PTV Nudix Hydrolase EIL75_RS07850 ENOG4105K2J Transcriptional regulator EIL75_RS07860 ENOG4106ETB IIa component EIL75_RS07870 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC EIL75_RS07875 ENOG4108HHA Transketolase EIL75_RS07880 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) EIL75_RS07885 ENOG4105CSX c4-dicarboxylate anaerobic carrier EIL75_RS07890 ENOG4105C6K Malic enzyme EIL75_RS07895 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) EIL75_RS07915 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 EIL75_RS07920 ENOG4107QWE )-transporter EIL75_RS07930 ENOG4105CHM Aminotransferase EIL75_RS07940 ENOG4107NQ8 LysR family Transcriptional regulator EIL75_RS07950 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain EIL75_RS07955 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) EIL75_RS07965 ENOG4105GKE subunit e EIL75_RS07970 ENOG4107QIZ NADH dehydrogenase EIL75_RS07975 ENOG4108IEH NADH dehydrogenase subunit g EIL75_RS07990 ENOG4107UFS subunit j EIL75_RS08000 ENOG4105D65 subunit l EIL75_RS08005 ENOG4105C8S subunit m EIL75_RS08020 ENOG4105CP2 von willebrand factor, type a EIL75_RS08035 ENOG4107YB6 acetyltransferase, (GNAT) family EIL75_RS08040 ENOG4105TNS Conserved Protein EIL75_RS08045 ENOG4105E4F Isochorismate synthase EIL75_RS08060 ENOG4108IPT Naphthoate synthase EIL75_RS08070 ENOG4105CEY Amp-dependent synthetase and ligase EIL75_RS08075 ENOG4106GZG polymyxin resistance protein B EIL75_RS08125 ENOG4108UII YfaZ family EIL75_RS08130 ENOG4108EWA cinA-like protein EIL75_RS08135 ENOG4107258 Transcriptional regulator EIL75_RS08145 ENOG4105CSP Major Facilitator Superfamily EIL75_RS08160 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is EIL75_RS08170 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) EIL75_RS08180 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A EIL75_RS08185 ENOG4105CXY transporter EIL75_RS08190 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase EIL75_RS08195 ENOG4105GZI Transcriptional regulator EIL75_RS08200 ENOG4105CZM Major Facilitator EIL75_RS08205 ENOG4105XPH Ferredoxin EIL75_RS08210 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EIL75_RS08215 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EIL75_RS08220 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) EIL75_RS08225 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EIL75_RS08230 ENOG4105BZU Histidine kinase EIL75_RS08235 ENOG41068CG regulatoR EIL75_RS08240 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC EIL75_RS08250 ENOG4105FCK Membrane EIL75_RS08255 ENOG4105CJ2 (LipO)protein EIL75_RS08260 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EIL75_RS08265 ENOG4105CF1 Alkylated DNA repair protein EIL75_RS08270 ENOG4105IBP Cyclic peptide transporter EIL75_RS08280 ENOG4108ZNS ferredoxin-type protein NapF EIL75_RS08285 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase EIL75_RS08295 ENOG4108BGM Quinol dehydrogenase periplasmic component EIL75_RS08300 ENOG4105GXZ Ferredoxin-type protein NapH EIL75_RS08305 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) EIL75_RS08310 ENOG4105CUW cytochrome C-TYPE protein EIL75_RS08320 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) EIL75_RS08325 ENOG41060IM Heme exporter protein EIL75_RS08330 ENOG4105X3C heme exporter protein EIL75_RS08335 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) EIL75_RS08340 ENOG4105DA4 cytochrome c-type biogenesis protein EIL75_RS08345 ENOG4107QX9 Thiol disulfide interChange protein EIL75_RS08350 ENOG4105KWW Biogenesis protein EIL75_RS08355 ENOG4105WH1 Two component transcriptional regulator luxr family EIL75_RS08380 ENOG4105E68 Sulfatase EIL75_RS08405 ENOG4105CFI type iii restriction protein res subunit EIL75_RS08410 ENOG4105I08 Pseudouridine synthase EIL75_RS08415 ENOG4105C2C drug resistance transporter, Bcr CflA EIL75_RS08420 ENOG4105HG6 EIL75_RS08425 ENOG4108JQ5 ABC transporter EIL75_RS08430 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component EIL75_RS08435 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component EIL75_RS08440 ENOG4105E43 Extracellular solute-binding protein, family 5 EIL75_RS08445 ENOG4105CXC rtn protein EIL75_RS08450 ENOG4107TT5 NLP P60 protein EIL75_RS08455 ENOG41076MN Phosphoesterase, PA-phosphatase related EIL75_RS08460 ENOG4105CKI cobalamin synthesis protein EIL75_RS08465 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) EIL75_RS08470 ENOG4105KRS Proteinase inhibitor EIL75_RS08485 ENOG4105S8Q sugar efflux transporter EIL75_RS08490 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein EIL75_RS08495 ENOG4105DE4 1-phosphofructokinase EIL75_RS08500 ENOG4105DM4 PTS System EIL75_RS08510 ENOG4105HMI Membrane EIL75_RS08515 ENOG4105DUM transcriptional regulator, lysR family EIL75_RS08520 ENOG4108IQI permease EIL75_RS08530 ENOG4105D05 Receptor EIL75_RS08535 ENOG4105CXY transporter EIL75_RS08540 ENOG4105EAC phosphoserine phosphatase EIL75_RS08545 ENOG4105EJQ L-serine dehydratase EIL75_RS08560 ENOG4105EUJ GTP cyclohydrolase i EIL75_RS08565 ENOG4105DHF Membrane EIL75_RS08570 ENOG41060NJ transcriptional regulator EIL75_RS08575 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator EIL75_RS08580 ENOG4105C2J ABC transporter EIL75_RS08585 ENOG4107SDZ Galactoside transport system permease protein mglC EIL75_RS08590 ENOG4107SJI Dehydrogenase EIL75_RS08595 ENOG4105BZ8 glutamate synthase EIL75_RS08600 ENOG4105Y9N Membrane EIL75_RS08605 ENOG4107GZ4 SanA protein EIL75_RS08615 ENOG41067MG lrgb family EIL75_RS08645 ENOG4108RXX maleylacetoacetate isomerase EIL75_RS08650 ENOG4105MSY salicylate hydroxylase EIL75_RS08655 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) EIL75_RS08665 ENOG4105ETP RND efflux system, outer membrane lipoprotein EIL75_RS08670 ENOG4105H9W Short-chain dehydrogenase reductase Sdr EIL75_RS08675 ENOG4105KHU inner membrane protein YohD EIL75_RS08680 ENOG41069YE inner membrane protein yohC EIL75_RS08685 ENOG41061WM D-Alanyl-D-Alanine EIL75_RS08690 ENOG4105CXG d-lactate dehydrogenase EIL75_RS08695 ENOG4107QK4 glycoside hydrolase, family 3 domain protein EIL75_RS08700 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system EIL75_RS08705 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component EIL75_RS08710 ENOG4108IJ8 ABC transporter EIL75_RS08715 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component EIL75_RS08730 ENOG4108HRK Histidine kinase EIL75_RS08735 ENOG4108NEV two component transcriptional regulator, LytTR family EIL75_RS08740 ENOG4108W15 Protein of unknown function (DUF1456) EIL75_RS08750 ENOG4108YCW (LipO)protein EIL75_RS08760 ENOG4105D1F ATP-binding protein EIL75_RS08775 ENOG4108MQF Chaperone EIL75_RS08780 ENOG4105CW0 outer membrane usher protein EIL75_RS08785 ENOG410662B Type-1 fimbrial protein EIL75_RS08790 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly EIL75_RS08800 ENOG4105DWF phosphomethylpyrimidine kinase EIL75_RS08805 ENOG4105FDP GntR family transcriptional regulator EIL75_RS08810 ENOG4108TFM Kinase, PfkB family EIL75_RS08815 ENOG4108KD5 ADP-ribosylation crystallin J1 EIL75_RS08820 ENOG4105EAA nucleoside EIL75_RS08825 ENOG4105EIE fructose-bisphosphate aldolase EIL75_RS08840 ENOG41090V3 Tir chaperone protein (CesT) family EIL75_RS08850 ENOG4105CFP Peptidase U32 EIL75_RS08880 ENOG41079JQ Membrane EIL75_RS08900 ENOG4105CNA YD repeat protein EIL75_RS08905 ENOG4105CNA YD repeat protein EIL75_RS08910 ENOG4105NUP lyase containing HEAT-repeat EIL75_RS08965 ENOG4105E3W Two component transcriptional regulator (Winged helix family EIL75_RS08970 ENOG4105EB3 Histidine kinase EIL75_RS09000 ENOG4105R8A Heat shock protein EIL75_RS09005 ENOG4105D03 DNA-3-methyladenine glycosylase II EIL75_RS09010 ENOG4105BZU Histidine kinase EIL75_RS09025 ENOG4108GAE asmA family EIL75_RS09030 ENOG4105EE5 Membrane protein terC EIL75_RS09035 ENOG4105DAY polysaccharide export protein EIL75_RS09040 ENOG4105KJF protein tyrosine phosphatase EIL75_RS09045 ENOG4105D75 Capsular exopolysaccharide family EIL75_RS09050 ENOG41090RK glycosyl transferase EIL75_RS09055 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB EIL75_RS09060 ENOG4107RXY Glycosyl transferase EIL75_RS09065 ENOG4108NYJ Colanic acid EIL75_RS09070 ENOG4105ECJ Glycosyl Transferase EIL75_RS09075 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF EIL75_RS09080 ENOG4105C0K Gdp-mannose 4,6-dehydratase EIL75_RS09085 ENOG4105C30 Nad-dependent epimerase dehydratase EIL75_RS09090 ENOG4105FGF GDP-mannose mannosyl hydrolase EIL75_RS09095 ENOG4106CD9 glycosyl transferase group 1 EIL75_RS09100 ENOG4105CJT Mannose-1-phosphate guanylyltransferase EIL75_RS09115 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) EIL75_RS09125 ENOG4105C6Y Udp-glucose 6-dehydrogenase EIL75_RS09130 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) EIL75_RS09135 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase EIL75_RS09150 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) EIL75_RS09155 ENOG4105ECC imidazole-glycerol-phosphate dehydratase EIL75_RS09165 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) EIL75_RS09180 ENOG4107SRH Nad-dependent epimerase dehydratase EIL75_RS09185 ENOG4105EQ1 Transcriptional regulator EIL75_RS09195 ENOG4105CUB amino acid EIL75_RS09200 ENOG4105CJB Exodeoxyribonuclease I EIL75_RS09215 ENOG4108J2R molybdopterin oxidoreductase EIL75_RS09220 ENOG4105QAX Iron-sulfur EIL75_RS09225 ENOG4108NWD Cytochrome EIL75_RS09230 ENOG4105DZ1 carboxypeptidase EIL75_RS09235 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) EIL75_RS09240 ENOG4105DR8 Membrane EIL75_RS09245 ENOG41090HJ UPF0265 protein EIL75_RS09250 ENOG4105JZC GHMP kinase EIL75_RS09255 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) EIL75_RS09260 ENOG4105KTW ethanolamine utilization protein EIL75_RS09265 ENOG4105M3W utilization protein EIL75_RS09275 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) EIL75_RS09280 ENOG4105C0A alcohol dehydrogenase EIL75_RS09285 ENOG4108EKI Dehydrogenase EIL75_RS09295 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml EIL75_RS09305 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) EIL75_RS09315 ENOG4105KNY Microcompartments protein EIL75_RS09325 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit EIL75_RS09330 ENOG4108ZFT Dehydratase small subunit EIL75_RS09335 ENOG4105YCI dehydratase medium subunit EIL75_RS09340 ENOG4105DMB glycerol dehydratase EIL75_RS09345 ENOG4105EHR propanediol utilization protein pduB EIL75_RS09350 ENOG4105KNY Microcompartments protein EIL75_RS09355 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) EIL75_RS09360 ENOG4107XVH Transcriptional regulator EIL75_RS09365 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) EIL75_RS09375 ENOG41081F0 Precorrin-8x methylmutase EIL75_RS09385 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase EIL75_RS09390 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase EIL75_RS09395 ENOG4105CIA precorrin-4 C(11)-methyltransferase EIL75_RS09400 ENOG4108P62 biosynthesis protein (CbiG) EIL75_RS09405 ENOG4105E4R Precorrin-3B C17-methyltransferase EIL75_RS09410 ENOG4105QUC reductase EIL75_RS09415 ENOG4107PPM cobalt chelatase EIL75_RS09420 ENOG4105DVK Precorrin-2 c20-methyltransferase EIL75_RS09425 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) EIL75_RS09430 ENOG4105W4R Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) EIL75_RS09435 ENOG4108V4M Cobalt abc transporter EIL75_RS09440 ENOG4108JJB ABC transporter EIL75_RS09450 ENOG4108YZT Adenosylcobinamide kinase EIL75_RS09465 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EIL75_RS09480 ENOG4105CXN decarboxylase EIL75_RS09495 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EIL75_RS09510 ENOG41085FC arsR family transcriptional regulator EIL75_RS09515 ENOG4108UXE Protein tyrosine phosphatase EIL75_RS09530 ENOG4105D6J arsenicaL-resistance protein EIL75_RS09550 ENOG4105UQX Mate efflux family protein EIL75_RS09575 ENOG4105FYV Amp nucleosidase EIL75_RS09650 ENOG4105HVQ Regulatory factor of maltose metabolism EIL75_RS09710 ENOG4105KT5 UmuD protein EIL75_RS09715 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EIL75_RS09730 ENOG4105FCK Membrane EIL75_RS09735 ENOG4105Y0K Inner membrane protein YedR EIL75_RS09740 ENOG4105EST Metal Dependent Phosphohydrolase EIL75_RS09745 ENOG4105DVF Cytosine-specific methyltransferase EIL75_RS09750 ENOG41090BB DNA mismatch endonuclease (vsr) EIL75_RS09755 ENOG4105FDR Membrane EIL75_RS09760 ENOG4105CKW Inner membrane protein yedI EIL75_RS09765 ENOG4105VNZ cytoplasmic protein EIL75_RS09775 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase EIL75_RS09780 ENOG4105YX3 cellular response to acidity EIL75_RS09790 ENOG4107TKS colanic acid capsular biosynthesis activation protein A EIL75_RS09795 ENOG4105D19 Role in flagellar biosynthesis (By similarity) EIL75_RS09800 ENOG4105VS8 Flagellar biosynthetic protein fliq EIL75_RS09805 ENOG4105CN7 Flagellar biosynthetic protein FliP EIL75_RS09810 ENOG4105K0P flagellar biosynthesis protein EIL75_RS09815 ENOG4105DD5 Flagellar motor switch protein EIL75_RS09820 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EIL75_RS09825 ENOG4107ZI8 flagellar basal body-associated protein flil EIL75_RS09830 ENOG4105WF4 Flagellar hook-length control protein EIL75_RS09835 ENOG4105GSA Flagellar export protein flij EIL75_RS09840 ENOG4108JIR Flagellum-specific ATP synthase EIL75_RS09845 ENOG41090PJ Flagellar assembly protein EIL75_RS09850 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EIL75_RS09855 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) EIL75_RS09875 ENOG41066VF YeeE YedE family protein EIL75_RS09880 ENOG4105JCU Inherit from NOG: (Lipo)protein EIL75_RS09885 ENOG4105E5K Alpha-amylase EIL75_RS09895 ENOG4105MQ3 flagellar protein FliS EIL75_RS09900 ENOG4105DTS flagellar hook-associated EIL75_RS09920 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EIL75_RS09925 ENOG4108M9K flagella biosynthesis protein FliZ EIL75_RS09930 ENOG4105EAB amino acid AbC transporter EIL75_RS09940 ENOG4105E5Q amino acid AbC transporter EIL75_RS09945 ENOG4105CDA abc transporter atp-binding protein EIL75_RS09950 ENOG4105VJY transcriptional regulator EIL75_RS09955 ENOG4105XVG cytoplasmic protein EIL75_RS09965 ENOG4105WH1 Two component transcriptional regulator luxr family EIL75_RS10010 ENOG4106RHG Yeca family EIL75_RS10015 ENOG4105E0U tyrosine-specific transport protein EIL75_RS10020 ENOG4105VVZ metal-binding protein EIL75_RS10025 ENOG41090A1 ferritin EIL75_RS10030 ENOG4105P23 (LipO)protein EIL75_RS10040 ENOG4108UEC Ferritin-like protein EIL75_RS10055 ENOG4108K4C ec 3.1.3.12 EIL75_RS10065 ENOG4108VA4 Universal stress protein EIL75_RS10075 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) EIL75_RS10080 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region EIL75_RS10085 ENOG4107RD7 Flagellar Motor Protein, MotA EIL75_RS10090 ENOG4105ER2 Ompa motb domain protein EIL75_RS10095 ENOG4105CBS Chea signal transduction histidine kinase EIL75_RS10100 ENOG4108V3W Chemotaxis protein, CheW EIL75_RS10105 ENOG4105C8Q Methyl-accepting chemotaxis EIL75_RS10110 ENOG4105BZU Histidine kinase EIL75_RS10115 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) EIL75_RS10120 ENOG4108VYJ response regulator receiver protein EIL75_RS10125 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) EIL75_RS10130 ENOG4105D00 flagellar biosynthetic protein flhB EIL75_RS10135 ENOG4105D7B Flagellar biosynthesis protein flha EIL75_RS10140 ENOG4105IRD Flagellar protein FlhE EIL75_RS10145 ENOG4105F5H Glycosyl Hydrolase Family 88 EIL75_RS10160 ENOG4106ZCM YecM protein EIL75_RS10180 ENOG4105WJG Glutathione EIL75_RS10185 ENOG41081XQ Conserved Protein EIL75_RS10190 ENOG4105D3W isochorismatase EIL75_RS10200 ENOG4108TIT dATP pyrophosphohydrolase EIL75_RS10205 ENOG4105CDY transcriptional regulatory protein EIL75_RS10215 ENOG4107S01 Repressor protein MetJ EIL75_RS10235 ENOG4105FAV ABC, transporter EIL75_RS10245 ENOG4105NXV High-affinity zinc uptake system protein EIL75_RS10250 ENOG4105DR5 peptidase EIL75_RS10255 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase EIL75_RS10260 ENOG4105CA9 Pyruvate kinase EIL75_RS10265 ENOG4106KNT transcriptional regulator EIL75_RS10275 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase EIL75_RS10280 ENOG4105C01 Dihydroxy-acid dehydratase EIL75_RS10285 ENOG4108UHU Aldolase EIL75_RS10295 ENOG4105X2V dna damage-inducible protein EIL75_RS10305 ENOG4108Q2J Inner membrane protein YebE EIL75_RS10310 ENOG4105CUG Oligopeptidase b EIL75_RS10315 ENOG4105UMD exodeoxyribonuclease X EIL75_RS10320 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase EIL75_RS10325 ENOG4105MPK DNA polymerase III subunit theta EIL75_RS10330 ENOG4105FXM Copper resistance protein EIL75_RS10335 ENOG4108PNC copper resistance EIL75_RS10340 ENOG4105NKT exported protein EIL75_RS10380 ENOG4105C22 threonyL-tRNA synthetase EIL75_RS10400 ENOG41064WM Uncharacterized protein YcgX EIL75_RS10410 ENOG4106EWC guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling EIL75_RS10420 ENOG4108R1E Serine threonine protein phosphatase 1 EIL75_RS10425 ENOG4105UVW uncharacterized protein yebW EIL75_RS10430 ENOG4105WT8 Protein of unknown function (DUF1480) EIL75_RS10440 ENOG4105DY2 Paraquat-inducible protein b EIL75_RS10445 ENOG4105H2K paraquat-inducible protein a EIL75_RS10450 ENOG4108ZGC gaf domain protein EIL75_RS10460 ENOG4105CN1 protease EIL75_RS10465 ENOG4105D0M Protease HtpX homolog EIL75_RS10470 ENOG4105C0R drug resistance transporter emrb qaca subfamily EIL75_RS10475 ENOG4105J4Q Transcriptional regulator EIL75_RS10485 ENOG4106CCY Protein MgrB homolog EIL75_RS10490 ENOG4105Q3Y exported protein EIL75_RS10505 ENOG4105CJN penicillin-binding protein EIL75_RS10510 ENOG4105DHI Methyltransferase EIL75_RS10525 ENOG4105F3R pts system mannose fructose sorbose family iid EIL75_RS10530 ENOG4105ETZ PTS System EIL75_RS10535 ENOG4105DAS pts system EIL75_RS10540 ENOG4105EE5 Membrane protein terC EIL75_RS10545 ENOG4107XTP (EAL) domain protein EIL75_RS10550 ENOG4105EJQ L-serine dehydratase EIL75_RS10560 ENOG4105CRQ synthase (Component I) EIL75_RS10565 ENOG4105X5C UPF0181 protein EIL75_RS10570 ENOG4105M4H endoribonuclease L-psp EIL75_RS10575 ENOG4105DVT helicase EIL75_RS10580 ENOG41072GX Peptidase M22 Glycoprotease EIL75_RS10585 ENOG4105Y4Z Outer Membrane Lipoprotein EIL75_RS10590 ENOG4105CEY Amp-dependent synthetase and ligase EIL75_RS10595 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) EIL75_RS10605 ENOG4107QMS site-determining protein EIL75_RS10620 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase EIL75_RS10635 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation EIL75_RS10645 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) EIL75_RS10660 ENOG4105ED1 spovr family EIL75_RS10670 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EIL75_RS10680 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A EIL75_RS10690 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) EIL75_RS10705 ENOG4105D82 Glutamate dehydrogenase EIL75_RS10715 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EIL75_RS10720 ENOG4105C4M (Ubiquinol oxidase) subunit I EIL75_RS10725 ENOG4105MVP hydrogenase-1 operon protein HyaF EIL75_RS10730 ENOG4108VXY Hydrogenase-1 operon protein HyaE EIL75_RS10735 ENOG4108USZ hydrogenase EIL75_RS10740 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit EIL75_RS10750 ENOG4105E3S small subunit EIL75_RS10765 ENOG4105C3G gtp-binding protein EIL75_RS10775 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria EIL75_RS10780 ENOG4105CHH sulfate transporter EIL75_RS10785 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EIL75_RS10800 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) EIL75_RS10810 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EIL75_RS10815 ENOG4108YY7 Invasion gene expression up-regulator SirB EIL75_RS10820 ENOG41063JG Transcriptional regulator EIL75_RS10830 ENOG4105EWV Sodium calcium exchanger membrane region EIL75_RS10835 ENOG4105WS7 Cation transport regulator EIL75_RS10840 ENOG41090EX DsrE family EIL75_RS10845 ENOG4105ID0 Putative invasin EIL75_RS10850 ENOG4105WH1 Two component transcriptional regulator luxr family EIL75_RS10855 ENOG4105BZU Histidine kinase EIL75_RS10865 ENOG4105DQQ Major facilitator superfamily MFS_1 EIL75_RS10870 ENOG4105CRU nitrate reductase, alpha subunit EIL75_RS10875 ENOG4108IUE nitrate reductase beta subunit EIL75_RS10880 ENOG4105R3A Nitrate reductase EIL75_RS10885 ENOG41076YT nitrate reductase, gamma subunit EIL75_RS10930 ENOG4105CIY formyltetrahydrofolate deformylase EIL75_RS10935 ENOG4105K5B UPF0225 protein EIL75_RS10940 ENOG4105D78 K07001 NTE family protein EIL75_RS10945 ENOG4105I93 response regulator EIL75_RS10950 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EIL75_RS10965 ENOG4105C0A alcohol dehydrogenase EIL75_RS10970 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein EIL75_RS10980 ENOG4107QSI ABC, transporter EIL75_RS10985 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EIL75_RS10990 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EIL75_RS10995 ENOG4105C3U ABC transporter EIL75_RS11000 ENOG4108JQ7 (ABC) transporter EIL75_RS11005 ENOG4105EYW Ion transport protein EIL75_RS11025 ENOG4105K9H YciI-like protein EIL75_RS11030 ENOG410822N TonB family EIL75_RS11035 ENOG4105NAU thioesterase Superfamily protein EIL75_RS11050 ENOG4105PI0 Ferredoxin EIL75_RS11055 ENOG4105EIF outer membrane protein W EIL75_RS11060 ENOG4105WEF catalase EIL75_RS11065 ENOG4108N8X transition metal ion binding EIL75_RS11070 ENOG4108Z9Z response to DNA damage stimulus EIL75_RS11090 ENOG4105DK0 Indole-3-glycerol phosphate synthase EIL75_RS11095 ENOG4108EFP Anthranilate synthase component II EIL75_RS11100 ENOG4105CRQ synthase (Component I) EIL75_RS11110 ENOG4105DB7 PHP domain protein EIL75_RS11115 ENOG4107RTD sua5 ycio yrdc ywlc family protein EIL75_RS11120 ENOG4105FE9 pseudouridine synthase EIL75_RS11125 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase EIL75_RS11130 ENOG4105UBK short-chain dehydrogenase reductase EIL75_RS11135 ENOG4105ERU peptidase EIL75_RS11140 ENOG4105RKX Protein of unknown function (DUF2498) EIL75_RS11145 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EIL75_RS11150 ENOG4107R11 Transcriptional regulator EIL75_RS11165 ENOG4107QM5 aconitate hydratase EIL75_RS11170 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) EIL75_RS11175 ENOG4105EYK Phosphatidylglycerophosphatase B EIL75_RS11180 ENOG4105Q4A inner membrane protein yciS EIL75_RS11185 ENOG4105CFV Tetratricopeptide repeat protein EIL75_RS11195 ENOG4108ZJT translation initiation factor, Sui1 EIL75_RS11200 ENOG41061RM osmotically inducible lipoprotein EIL75_RS11205 ENOG4105N2W Transcriptional regulator EIL75_RS11215 ENOG4105BZU Histidine kinase EIL75_RS11225 ENOG4105Q4T oxidoreductase EIL75_RS11230 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH EIL75_RS11255 ENOG4108JQ2 peptide transport system atp-binding protein EIL75_RS11260 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein EIL75_RS11265 ENOG4108EU3 peptide transport system, permease EIL75_RS11270 ENOG4108EKA peptide transport system, permease EIL75_RS11275 ENOG4108J59 Extracellular solute-binding protein, family 5 EIL75_RS11280 ENOG4105E51 psp operon transcriptional activator EIL75_RS11285 ENOG41087YS Phage shock protein A EIL75_RS11290 ENOG4105YYT phage shock protein B EIL75_RS11295 ENOG4105FM1 phage shock protein C EIL75_RS11300 ENOG4105NNG Peripheral inner membrane phage-shock protein EIL75_RS11305 ENOG4105K8Z Phage shock protein EIL75_RS11310 ENOG4105CM6 amino acid regulated cytosolic protein EIL75_RS11320 ENOG4108JU8 Transcriptional regulator EIL75_RS11325 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) EIL75_RS11330 ENOG4107S8C mandelate racemase muconate lactonizing EIL75_RS11335 ENOG4105KXI murein peptide amidase A EIL75_RS11340 ENOG4107QSI ABC, transporter EIL75_RS11365 ENOG4105EJC lysr family transcriptional regulator EIL75_RS11375 ENOG4105C44 Serine transporter EIL75_RS11380 ENOG4105C28 cystathionine EIL75_RS11390 ENOG4105HEI LysR family (Transcriptional regulator EIL75_RS11395 ENOG4105CV8 reductase EIL75_RS11400 ENOG4105F6U Short-chain dehydrogenase reductase Sdr EIL75_RS11405 ENOG4108XFH Transcriptional regulator EIL75_RS11420 ENOG4106PHM regulatory protein EIL75_RS11445 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) EIL75_RS11465 ENOG4105D64 Mechanosensitive ion channel EIL75_RS11470 ENOG4105S5I Membrane EIL75_RS11475 ENOG4105Q9Y Universal stress protein EIL75_RS11480 ENOG4105DS0 Transcriptional regulator, Crp Fnr family EIL75_RS11485 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EIL75_RS11490 ENOG4108DG9 Smr protein MutS2 EIL75_RS11495 ENOG4105C8Q Methyl-accepting chemotaxis EIL75_RS11510 ENOG4105C1J atp-dependent rna helicase EIL75_RS11530 ENOG410814C multidrug resistance protein EIL75_RS11535 ENOG4108RW8 Universal stress protein F EIL75_RS11540 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) EIL75_RS11550 ENOG4105IKK cytoplasmic protein EIL75_RS11555 ENOG41090X5 Heat shock protein hslJ EIL75_RS11560 ENOG4105C5I Dehydrogenase EIL75_RS11565 ENOG4107H52 Dicarboxylate transport EIL75_RS11570 ENOG410689M (LipO)protein EIL75_RS11575 ENOG4105WXT Conserved Protein EIL75_RS11590 ENOG4105CQ7 ATP-dependent helicase EIL75_RS11595 ENOG4107DB1 DUF218 domain EIL75_RS11600 ENOG4105CPW cytochrome b561 EIL75_RS11605 ENOG4108WF3 methyltransferase EIL75_RS11615 ENOG4105E5Q amino acid AbC transporter EIL75_RS11625 ENOG4105E5Q amino acid AbC transporter EIL75_RS11630 ENOG4107R0W ABC transporter EIL75_RS11640 ENOG4107ZUJ lipid metabolic process EIL75_RS11670 ENOG4105C8Q Methyl-accepting chemotaxis EIL75_RS11675 ENOG4105DDW LysR family Transcriptional regulator EIL75_RS11680 ENOG4105E32 cytoplasmic protein EIL75_RS11685 ENOG4105EBR Carboxylesterase EIL75_RS11710 ENOG4108PQ7 sgc region transcriptional regulator EIL75_RS11715 ENOG4108RK0 3-epimerase EIL75_RS11720 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) EIL75_RS11725 ENOG4106P19 photosystem i assembly btpa EIL75_RS11730 ENOG4105DT3 PTS system, galactitol-specific IIc component EIL75_RS11735 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) EIL75_RS11740 ENOG4105CN9 Peptidase m42 family protein EIL75_RS11745 ENOG4108Z9I -acetyltransferase EIL75_RS11750 ENOG4107WE3 acetyltransferase YdcK EIL75_RS11755 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein EIL75_RS11760 ENOG41088CC tellurite resistance protein tehB EIL75_RS11765 ENOG4108KKZ (LipO)protein EIL75_RS11770 ENOG4105DKK Benzoate EIL75_RS11775 ENOG4108JCI Transcriptional regulator EIL75_RS11780 ENOG4105CFP Peptidase U32 EIL75_RS11785 ENOG4105RR0 Protein of unknown function (DUF2554) EIL75_RS11805 ENOG4108UQS dipeptidase EIL75_RS11810 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EIL75_RS11825 ENOG410654E Membrane EIL75_RS11845 ENOG4105R71 cytoplasmic protein EIL75_RS11850 ENOG4108T9Y Inner membrane protein ydcZ EIL75_RS11855 ENOG4108Z7F N-acetyltransferase EIL75_RS11860 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein EIL75_RS11865 ENOG4108WYP Transcriptional regulator EIL75_RS11870 ENOG4105CHB tonB-dependent Receptor EIL75_RS11875 ENOG4108NS2 receptor EIL75_RS11880 ENOG4105SUV lipoprotein YgdR EIL75_RS11885 ENOG4105C85 amino acid EIL75_RS11900 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase EIL75_RS11905 ENOG4105JAB phenazine biosynthesis protein, phzf family EIL75_RS11910 ENOG4105D0D Nitrate reductase 2, gamma subunit EIL75_RS11915 ENOG4108NZN Respiratory nitrate reductase 2 delta chain EIL75_RS11920 ENOG4108IUE nitrate reductase beta subunit EIL75_RS11925 ENOG4105CRU nitrate reductase, alpha subunit EIL75_RS11930 ENOG4107QND Nitrite extrusion protein EIL75_RS11975 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein EIL75_RS11980 ENOG4108MG3 formate dehydrogenase EIL75_RS11985 ENOG4105DQ4 alcohol dehydrogenase EIL75_RS12000 ENOG4105TPS biofilm-dependent modulation protein EIL75_RS12005 ENOG4108Z9K Osmotically inducible protein EIL75_RS12010 ENOG4105XXV Acid-resistance protein EIL75_RS12020 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) EIL75_RS12035 ENOG4105C87 Aminotransferase class I and II EIL75_RS12040 ENOG4105DFD Na H antiporter EIL75_RS12045 ENOG41060NJ transcriptional regulator EIL75_RS12105 ENOG4108UQ8 endoribonuclease L-psp EIL75_RS12110 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) EIL75_RS12140 ENOG4105CPQ Dehydrogenase EIL75_RS12145 ENOG4105C6F GntR Family Transcriptional Regulator EIL75_RS12160 ENOG4105DPX Hydrogenase, large subunit EIL75_RS12165 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit EIL75_RS12185 ENOG4105MVP hydrogenase-1 operon protein HyaF EIL75_RS12210 ENOG4105FFC UPF0187 protein EIL75_RS12215 ENOG4105M0C cytoplasmic protein EIL75_RS12225 ENOG4105C26 Dehydrogenase EIL75_RS12230 ENOG4105EGI Transcriptional regulator EIL75_RS12250 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes EIL75_RS12255 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF EIL75_RS12260 ENOG4106DNR multiple antibiotic resistance protein EIL75_RS12265 ENOG4108594 Permease of the drug metabolite transporter EIL75_RS12270 ENOG4105E5W Transporter EIL75_RS12285 ENOG4108YDI single-species biofilm formation on inanimate substrate EIL75_RS12290 ENOG4108WTK competence damage-inducible protein EIL75_RS12305 ENOG4105DGW oligopeptidase A EIL75_RS12310 ENOG4105EMU Dehydrogenase EIL75_RS12315 ENOG4107XBN GntR Family Transcriptional Regulator EIL75_RS12320 ENOG41061EV selenium-binding protein YdfZ EIL75_RS12325 ENOG4105DEI Mannitol dehydrogenase EIL75_RS12340 ENOG4105CPQ Dehydrogenase EIL75_RS12360 ENOG4108MK9 spermidine N(1)-acetyltransferase EIL75_RS12370 ENOG4105KBG Protein of unknown function (DUF1161) EIL75_RS12375 ENOG4107QY8 reductase EIL75_RS12380 ENOG4105C3J Cysteine desulfurase EIL75_RS12385 ENOG4105QAX Iron-sulfur EIL75_RS12390 ENOG4107KGK dmso reductase anchor subunit EIL75_RS12395 ENOG4108NEM leader-binding protein dmsD EIL75_RS12400 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component EIL75_RS12405 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system EIL75_RS12410 ENOG4105E90 ABC transporter EIL75_RS12415 ENOG4108IJ8 ABC transporter EIL75_RS12420 ENOG4105CMQ Chloride channel EIL75_RS12425 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) EIL75_RS12430 ENOG4105DAG ROK family EIL75_RS12435 ENOG4106NZI LysR family Transcriptional regulator EIL75_RS12440 ENOG4105D94 Major Facilitator Superfamily EIL75_RS12450 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap EIL75_RS12470 ENOG4105DSF transport protein EIL75_RS12475 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EIL75_RS12480 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EIL75_RS12485 ENOG4105C5D exported protein EIL75_RS12490 ENOG4105D5Q Arginine ornithine antiporter EIL75_RS12495 ENOG4105RA2 Membrane EIL75_RS12500 ENOG4107EXC regulatoR EIL75_RS12510 ENOG4105FCK Membrane EIL75_RS12515 ENOG4105CPN adenine deaminase EIL75_RS12520 ENOG4105JJR Histidine kinase EIL75_RS12530 ENOG4105C9Q fumarate hydratase class II EIL75_RS12535 ENOG4107GFK fumarate EIL75_RS12540 ENOG4105EIP mannose-6-phosphate isomerase EIL75_RS12545 ENOG4106J39 exported protein EIL75_RS12555 ENOG4105C87 Aminotransferase class I and II EIL75_RS12565 ENOG4105D9R oxidoreductase EIL75_RS12570 ENOG4106C6R beta-lactam resistance protein EIL75_RS12580 ENOG4105M9B inner membrane protein ydgK EIL75_RS12605 ENOG4108UQQ Electron transport complex EIL75_RS12615 ENOG4105CSM endonuclease III EIL75_RS12620 ENOG4105DUX Transporter EIL75_RS12625 ENOG4108K3A Glutathione S-transferase EIL75_RS12645 ENOG410642K Lysozyme inhibitor EIL75_RS12655 ENOG4108XTF Outer Membrane Lipoprotein EIL75_RS12670 ENOG4105Y49 secretion protein, HlyD family EIL75_RS12675 ENOG4105DSW Fusaric acid resistance protein EIL75_RS12680 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EIL75_RS12685 ENOG4107RGM aldo keto reductase EIL75_RS12690 ENOG4105XZD Fe-S protein EIL75_RS12695 ENOG4108WUH Transcriptional regulator, TetR family EIL75_RS12700 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EIL75_RS12705 ENOG4108UYE Lactoylglutathione lyase EIL75_RS12710 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) EIL75_RS12720 ENOG4105M2J Glutaredoxin EIL75_RS12725 ENOG4105K4H Nlp p60 protein EIL75_RS12730 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EIL75_RS12745 ENOG4105F52 Transcriptional regulator EIL75_RS12750 ENOG4105CZQ inner membrane transport protein YdhC EIL75_RS12755 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase EIL75_RS12760 ENOG4108R6K riboflavin synthase, subunit alpha EIL75_RS12780 ENOG4108IUF type iii secretion EIL75_RS12785 ENOG4108TN6 type iii secretion EIL75_RS12790 ENOG41083GP type iii secretion EIL75_RS12795 ENOG4108HHI Type III secretion system protein EIL75_RS12800 ENOG41063Q7 Type III secretion system protein EIL75_RS12815 ENOG4108JIR Flagellum-specific ATP synthase EIL75_RS12825 ENOG4106H1D secretion system apparatus protein EIL75_RS12830 ENOG4105UQF type iii secretion EIL75_RS12835 ENOG4106563 type III secretion system apparatus protein EIL75_RS12885 ENOG4106FZW pathogenicity island effector protein EIL75_RS12890 ENOG4108SZ7 secretion system effector EIL75_RS12900 ENOG4105ZQI secreted protein EIL75_RS12930 ENOG4105BZU Histidine kinase EIL75_RS12940 ENOG4108XDN Transcriptional regulator EIL75_RS12945 ENOG4107SEY Conserved Protein EIL75_RS12950 ENOG4105RFR Protein of unknown function (DUF2767) EIL75_RS12955 ENOG4108ZXC Two component transcriptional regulator, luxr family EIL75_RS12960 ENOG4106AFQ Histidine kinase EIL75_RS12965 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein EIL75_RS12970 ENOG4106WHD Tetrathionate reductase EIL75_RS12975 ENOG4105DB1 molybdopterin oxidoreductase EIL75_RS12980 ENOG4108RVA ribokinase EIL75_RS12990 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) EIL75_RS12995 ENOG4105CUB amino acid EIL75_RS13000 ENOG4105CA9 Pyruvate kinase EIL75_RS13025 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EIL75_RS13040 ENOG4105JRK feS assembly protein SufD EIL75_RS13045 ENOG4105C3K feS assembly ATPase SufC EIL75_RS13050 ENOG4105DIW FeS assembly protein SUFB EIL75_RS13055 ENOG4108Z4V iron-sulfur cluster assembly EIL75_RS13060 ENOG4108ETY sodium dicarboxylate symporter EIL75_RS13065 ENOG410671Z uncharacterized protein ydiH EIL75_RS13070 ENOG4105KA0 thioesterase Superfamily protein EIL75_RS13075 ENOG4105CQB FAD linked oxidase domain protein EIL75_RS13080 ENOG4105IPI Membrane EIL75_RS13090 ENOG4105SUA Ydil protein EIL75_RS13095 ENOG4105EMV Major Facilitator EIL75_RS13100 ENOG4105EMV Major Facilitator EIL75_RS13115 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) EIL75_RS13120 ENOG4105C1G acyl-Coa dehydrogenase EIL75_RS13125 ENOG4105W4W Transcriptional regulator EIL75_RS13130 ENOG4105CV7 Electron transfer flavoprotein EIL75_RS13135 ENOG4105C10 Electron transfer flavoprotein EIL75_RS13140 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase EIL75_RS13145 ENOG41090P5 ferredoxin-like protein EIL75_RS13150 ENOG4105CEY Amp-dependent synthetase and ligase EIL75_RS13155 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) EIL75_RS13165 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EIL75_RS13185 ENOG4108QBX (LipO)protein EIL75_RS13195 ENOG4108V06 Glutathione peroxidase EIL75_RS13205 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) EIL75_RS13210 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) EIL75_RS13230 ENOG41082NX 50s ribosomal protein l35 EIL75_RS13235 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) EIL75_RS13260 ENOG4108NE3 Salt-induced outer membrane protein EIL75_RS13265 ENOG4105DE4 1-phosphofructokinase EIL75_RS13270 ENOG4105P10 Uncharacterized protein ydiZ EIL75_RS13280 ENOG4107PN8 YfeABCD locus regulator EIL75_RS13285 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 EIL75_RS13290 ENOG4107K5X Membrane-bound metal-dependent hydrolase EIL75_RS13295 ENOG4108ETY sodium dicarboxylate symporter EIL75_RS13305 ENOG4105CH6 catalase EIL75_RS13315 ENOG4105F8D glycoside hydrolase family 4 EIL75_RS13320 ENOG4105EZV Transcriptional regulator EIL75_RS13325 ENOG4105VCP PTS System EIL75_RS13330 ENOG4105CK1 PTS System EIL75_RS13335 ENOG4105VZJ PTS System EIL75_RS13345 ENOG4105KKI DNA-binding transcriptional activator OsmE EIL75_RS13355 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) EIL75_RS13360 ENOG4108SPG Periplasmic Protein EIL75_RS13370 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) EIL75_RS13375 ENOG4105C26 Dehydrogenase EIL75_RS13390 ENOG4105CGK Exodeoxyribonuclease III EIL75_RS13395 ENOG4105M6F mutator MutT protein EIL75_RS13400 ENOG4105MTM Protein of unknown function (DUF1496) EIL75_RS13405 ENOG4105D82 Glutamate dehydrogenase EIL75_RS13410 ENOG4108IYH Dna topoisomerase EIL75_RS13415 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) EIL75_RS13420 ENOG41069NU Nitroreductase EIL75_RS13425 ENOG4105D07 Signal peptide peptidase, SppA EIL75_RS13430 ENOG4105HDK L-asparaginase EIL75_RS13435 ENOG4108RWI nicotinamidase EIL75_RS13440 ENOG4105VUT cytoplasmic protein EIL75_RS13450 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EIL75_RS13460 ENOG4105DSB aldose 1-epimerase EIL75_RS13465 ENOG4105CV8 reductase EIL75_RS13470 ENOG4105C4X radical SAM domain protein EIL75_RS13475 ENOG4105GNX MltA-interacting MipA family protein EIL75_RS13480 ENOG4105CYN Serine protein kinase EIL75_RS13495 ENOG4108KHP Diguanylate cyclase EIL75_RS13500 ENOG4108KXH Ybak prolyl-tRNA synthetase associated EIL75_RS13515 ENOG4105R1U AraC Family Transcriptional Regulator EIL75_RS13520 ENOG4105DJ2 Major Facilitator Superfamily EIL75_RS13525 ENOG4105K78 MarR family Transcriptional regulator EIL75_RS13535 ENOG4105UCG Domain of unknown function (DUF333) EIL75_RS13540 ENOG4106G4W EIL75_RS13545 ENOG4105Y3U Transglycosylase-associated protein EIL75_RS13560 ENOG4105YP6 Domain of unknown function (DUF1869) EIL75_RS13565 ENOG4108YS1 cytoplasmic protein EIL75_RS13580 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) EIL75_RS13590 ENOG4108Z6Z Transcriptional regulator EIL75_RS13605 ENOG4108MEK Metal-binding protein YodA EIL75_RS13620 ENOG4105D64 Mechanosensitive ion channel EIL75_RS13625 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) EIL75_RS13630 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) EIL75_RS13655 ENOG4108VKM cytochrome b561 EIL75_RS13665 ENOG4108ZNX Heat shock protein EIL75_RS13695 ENOG4105H38 Membrane EIL75_RS13715 ENOG41060EU Cold shock-like protein EIL75_RS13720 ENOG4106F2Y RICIN EIL75_RS13725 ENOG4105Y50 Virulence Protein EIL75_RS13765 ENOG4108HMX isocitrate dehydrogenase (NADP) EIL75_RS13770 ENOG4108R99 pseudouridine synthase EIL75_RS13795 ENOG4107QTF adenylosuccinate lyase EIL75_RS13810 ENOG4105EZE Cupin 4 family protein EIL75_RS13825 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EIL75_RS13840 ENOG4105D38 putrescine abc transporter EIL75_RS13845 ENOG4108HM4 ABC transporter EIL75_RS13850 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EIL75_RS13860 ENOG4105D60 lipoprotein releasing system transmembrane protein EIL75_RS13865 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) EIL75_RS13870 ENOG4105D60 lipoprotein releasing system transmembrane protein EIL75_RS13875 ENOG4108JA2 transcriptioN-repair coupling factor EIL75_RS13880 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EIL75_RS13885 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction EIL75_RS13890 ENOG4108IND Tetr family transcriptional regulator EIL75_RS13895 ENOG4107MBR 17 kDa surface antigen EIL75_RS13900 ENOG4105CEP NADH dehydrogenase EIL75_RS13920 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) EIL75_RS13925 ENOG41090DQ Lipoprotein EIL75_RS13930 ENOG4105K59 histidine triad (HIT) protein EIL75_RS13935 ENOG4105CNM Receptor EIL75_RS13940 ENOG4105CI1 PTS System EIL75_RS13945 ENOG4105F8V Hydrolase, tatD family EIL75_RS13950 ENOG4107QRG dna polymerase iii EIL75_RS13960 ENOG4105HHA aminodeoxychorismate lyase EIL75_RS13965 ENOG4105YAZ 4-amino-4-deoxychorismate lyase EIL75_RS13970 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EIL75_RS13975 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) EIL75_RS13980 ENOG4105CHR reductase EIL75_RS13985 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EIL75_RS14005 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein EIL75_RS14010 ENOG4108UHJ MAF-like protein EIL75_RS14025 ENOG4105EI2 Pseudouridine synthase EIL75_RS14035 ENOG4107QQB Ribonuclease E EIL75_RS14045 ENOG4105DTJ flagellar hook-associated protein EIL75_RS14050 ENOG4105E1Q flagellar hook-associated protein EIL75_RS14055 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj EIL75_RS14070 ENOG4105CGA flagellar basal-body rod protein FlgG EIL75_RS14075 ENOG4108KPB Flagellar basal-body rod protein FlgF EIL75_RS14080 ENOG4105BZE flagellar hook protein, FlgE EIL75_RS14085 ENOG4105W00 Flagellar hook capping protein EIL75_RS14090 ENOG4108ZC9 flagellar basal-body rod protein flgc EIL75_RS14095 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) EIL75_RS14105 ENOG4105CKS Flagella basal body P-ring formation protein flgA EIL75_RS14110 ENOG4105M9M anti-sigma28 factor FlgM EIL75_RS14115 ENOG4105QVD Flagella synthesis protein FlgN EIL75_RS14120 ENOG4105CJR Integral membrane protein (MviN EIL75_RS14125 ENOG4105EP9 oxidoreductase EIL75_RS14135 ENOG4105D9U N-acetyltransferase EIL75_RS14145 ENOG4105E9S glutaredoxin 2 EIL75_RS14150 ENOG4105F3T (LipO)protein EIL75_RS14160 ENOG4105MEA DNA damage-inducible protein i EIL75_RS14165 ENOG4105PVA Biofilm formation regulatory protein BssS EIL75_RS14175 ENOG4106974 biofilm formation EIL75_RS14180 ENOG4105DS1 cytochrome b561 EIL75_RS14185 ENOG4108YYC ycei family EIL75_RS14195 ENOG4105D1S lipid A biosynthesis EIL75_RS14210 ENOG4108W47 Acidic protein msyB EIL75_RS14215 ENOG4105NAC (LipO)protein EIL75_RS14220 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) EIL75_RS14240 ENOG4107RZC phospholipase d EIL75_RS14250 ENOG41068SS EIL75_RS14255 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) EIL75_RS14260 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin EIL75_RS14265 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers EIL75_RS14270 ENOG41086KC Transcriptional regulator EIL75_RS14275 ENOG4108XDW curli assembly protein CsgE EIL75_RS14280 ENOG4108WYR Curli production assembly transport component, CsgF EIL75_RS14285 ENOG4105P8Q Curli production assembly transport component CsgG EIL75_RS14290 ENOG4108UQ5 membrane protein YcdZ EIL75_RS14295 ENOG4107XHZ cytoplasmic chaperone TorD family protein EIL75_RS14350 ENOG4105D5M phosphate starvation-inducible protein EIL75_RS14360 ENOG4105CK7 Sodium proline symporter EIL75_RS14375 ENOG4108R86 Transcriptional regulator EIL75_RS14380 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 EIL75_RS14385 ENOG4105CS1 NAD(P)H quinone oxidoreductase EIL75_RS14390 ENOG4105XH3 EIL75_RS14395 ENOG4105D6F Phosphatase EIL75_RS14400 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EIL75_RS14405 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) EIL75_RS14410 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) EIL75_RS14480 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase EIL75_RS14485 ENOG4105C26 Dehydrogenase EIL75_RS14495 ENOG4108V8F Transcriptional regulator, MarR family EIL75_RS14500 ENOG4105EFA 4-hydroxyphenylacetate EIL75_RS14505 ENOG4107UWN reductase EIL75_RS14515 ENOG4105VT2 5-hydroxyisourate hydrolase EIL75_RS14520 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EIL75_RS14525 ENOG4107ZY3 Histidine kinase EIL75_RS14540 ENOG4106YSC EIL75_RS14545 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell EIL75_RS14555 ENOG41084BJ Pentapeptide repeat protein EIL75_RS14570 ENOG4108MN8 Membrane EIL75_RS14580 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 EIL75_RS14590 ENOG4108V1U phospholipid-binding protein EIL75_RS14605 ENOG4105K4P CoA-binding domain protein EIL75_RS14615 ENOG4108Z5K methylglyoxal synthase EIL75_RS14620 ENOG41088T4 Helicase IV EIL75_RS14625 ENOG410901E Membrane EIL75_RS14630 ENOG4105EM2 membrane EIL75_RS14635 ENOG4108RZ1 DNA transformation protein EIL75_RS14645 ENOG4105UYK outer membrane protein a EIL75_RS14655 ENOG4105DAN ATP-dependent protease EIL75_RS14665 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) EIL75_RS14670 ENOG4108Q2G (LipO)protein EIL75_RS14675 ENOG4105DY2 Paraquat-inducible protein b EIL75_RS14680 ENOG4105F1S paraquat-inducible protein a EIL75_RS14685 ENOG4105C5H ABC transporter EIL75_RS14695 ENOG4105QVC MOSC domain-containing protein EIL75_RS14700 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) EIL75_RS14710 ENOG4105CD8 aminopeptidase N EIL75_RS14725 ENOG4107RCH Diaminopropionate ammonia-lyase EIL75_RS14740 ENOG4105C5S asparaginyl-tRNA synthetase EIL75_RS14745 ENOG4105FCK Membrane EIL75_RS14750 ENOG4105CGF Aromatic amino acid aminotransferase EIL75_RS14755 ENOG4105C5X domain protein EIL75_RS14760 ENOG4105EAQ (twin-arginine translocation) pathway signal EIL75_RS14765 ENOG4105DIT ErfK YbiS YcfS YnhG family protein EIL75_RS14780 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) EIL75_RS14790 ENOG4106371 Methyltransferase EIL75_RS14795 ENOG4107S90 membrAne EIL75_RS14800 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups EIL75_RS14815 ENOG4105T0Z Conserved Protein EIL75_RS14825 ENOG4105BZ1 (ABC) transporter EIL75_RS14830 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 EIL75_RS14835 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) EIL75_RS14840 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) EIL75_RS14850 ENOG4108K0D peptidase, M48 EIL75_RS14865 ENOG4107VMU Membrane EIL75_RS14870 ENOG4105DDY UPF0142 protein ycaO EIL75_RS14875 ENOG4105TMB Formate nitrite transporter EIL75_RS14880 ENOG4105C6N Formate acetyltransferase EIL75_RS14885 ENOG4105GUS EIL75_RS14890 ENOG4105F1A Pyruvate formate-lyase EIL75_RS14895 ENOG4105E5D amino acid EIL75_RS14905 ENOG4107KGK dmso reductase anchor subunit EIL75_RS14910 ENOG4105QAX Iron-sulfur EIL75_RS14915 ENOG4107QY8 reductase EIL75_RS14925 ENOG4105D1H recombination factor protein RarA EIL75_RS14935 ENOG4105CNU cell division protein FtsK EIL75_RS14940 ENOG4105EW9 transcriptional regulator AsnC family EIL75_RS14945 ENOG4105C3M thioredoxin reductase EIL75_RS14950 ENOG4108JJ9 ABC, transporter EIL75_RS14955 ENOG4108JJ8 (ABC) transporter EIL75_RS14970 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) EIL75_RS14975 ENOG4105HEI LysR family (Transcriptional regulator EIL75_RS14980 ENOG4105EUB pirin domain protein EIL75_RS14985 ENOG4105CHJ isochorismatase hydrolase EIL75_RS15000 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EIL75_RS15010 ENOG4105VEQ Cold shock protein EIL75_RS15015 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EIL75_RS15020 ENOG4105DJY efflux transporter, rnd family, mfp subunit EIL75_RS15025 ENOG4108MJ5 VirK protein EIL75_RS15030 ENOG4105CPB ATP-dependent endonuclease of the OLD family EIL75_RS15035 ENOG4105DWU Membrane EIL75_RS15045 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EIL75_RS15050 ENOG4105C7K acetolactate synthase EIL75_RS15055 ENOG4105C5W Aldolase EIL75_RS15060 ENOG4105CGD Nad-dependent epimerase dehydratase EIL75_RS15065 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase EIL75_RS15070 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EIL75_RS15080 ENOG41064MM (LipO)protein EIL75_RS15085 ENOG4105E5Z arginine transporter ATP-binding subunit EIL75_RS15090 ENOG4106PMH Extracellular solute-binding protein family 3 EIL75_RS15095 ENOG4105GBT ABC transporter EIL75_RS15100 ENOG4105DMR ABC, transporter EIL75_RS15105 ENOG4106TNF Periplasmic binding protein EIL75_RS15130 ENOG4105RBQ inner membrane protein ybjO EIL75_RS15135 ENOG4105D38 putrescine abc transporter EIL75_RS15140 ENOG4105F38 ABC transporter, permease EIL75_RS15145 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EIL75_RS15150 ENOG4107RUE extracellular solute-binding protein family 1 EIL75_RS15155 ENOG4108RMJ sensory transduction regulator EIL75_RS15165 ENOG4108DBC nitroreductase EIL75_RS15170 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress EIL75_RS15175 ENOG41090BQ Glutaredoxin EIL75_RS15180 ENOG4105GWF inner membrane protein YbjM EIL75_RS15195 ENOG4108RFG Tetr family transcriptional regulator EIL75_RS15200 ENOG4106UW1 Major Facilitator superfamily EIL75_RS15205 ENOG4108HCJ Hydrolase EIL75_RS15210 ENOG4107QF7 multi-drug EIL75_RS15215 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase EIL75_RS15220 ENOG4107FB0 transcriptional regulator DeoR family EIL75_RS15225 ENOG4105DZ1 carboxypeptidase EIL75_RS15230 ENOG4108TGY Glutathione S-transferase EIL75_RS15235 ENOG4105D8V Glucose sorbosone dehydrogenase EIL75_RS15240 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway EIL75_RS15260 ENOG4105DEF Extracellular solute-binding protein, family 5 EIL75_RS15265 ENOG4108JQ6 ABC transporter EIL75_RS15270 ENOG4105D44 asparaginase EIL75_RS15275 ENOG4105CVM Molybdenum cofactor synthesis domain protein EIL75_RS15280 ENOG4105D06 uba thif-type nad fad binding protein EIL75_RS15285 ENOG4105F1A Pyruvate formate-lyase EIL75_RS15295 ENOG4108HCJ Hydrolase EIL75_RS15300 ENOG41072TH Protein of unknown function (DUF1479) EIL75_RS15320 ENOG4105C5H ABC transporter EIL75_RS15325 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EIL75_RS15330 ENOG4105F4P )-transporter EIL75_RS15335 ENOG4105KST dependent repressor EIL75_RS15345 ENOG4108I6E Sulfatase EIL75_RS15350 ENOG4108T1M outer membrane protein x EIL75_RS15365 ENOG4107R0W ABC transporter EIL75_RS15370 ENOG4105E5Q amino acid AbC transporter EIL75_RS15375 ENOG4105CDA abc transporter atp-binding protein EIL75_RS15380 ENOG4105D8X mechanosensitive ion channel EIL75_RS15390 ENOG4105KSC Transcriptional regulator, TraR DksA family EIL75_RS15395 ENOG4105VR4 UPF0379 protein ybiJ EIL75_RS15400 ENOG4108MTB glycosyl transferase family EIL75_RS15405 ENOG4105DVT helicase EIL75_RS15410 ENOG4105C1J atp-dependent rna helicase EIL75_RS15415 ENOG4105C0A alcohol dehydrogenase EIL75_RS15435 ENOG4105DJB Major Facilitator Superfamily EIL75_RS15440 ENOG4108PZW LysR family Transcriptional regulator EIL75_RS15445 ENOG4107MVR Transcriptional regulator EIL75_RS15455 ENOG4105CJ1 ABC, transporter EIL75_RS15460 ENOG4107QWP ABC-2 type transporter EIL75_RS15465 ENOG4107QWP ABC-2 type transporter EIL75_RS15470 ENOG4105I9U inner membrane protein ybhQ EIL75_RS15475 ENOG4105X23 Endonuclease Exonuclease phosphatase EIL75_RS15480 ENOG4105DZQ phospholipase D Transphosphatidylase EIL75_RS15485 ENOG4107UXM Membrane EIL75_RS15505 ENOG4105HFZ Membrane EIL75_RS15510 ENOG4108ZAF Molybdopterin EIL75_RS15515 ENOG4105M00 molybdopterin converting factor, subunit 1 EIL75_RS15525 ENOG4108RIR Molybdenum cofactor biosynthesis protein EIL75_RS15535 ENOG4105CHW UPF0052 protein EIL75_RS15555 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) EIL75_RS15560 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EIL75_RS15575 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EIL75_RS15580 ENOG4108V1U phospholipid-binding protein EIL75_RS15610 ENOG4105NBR Pectinesterase EIL75_RS15620 ENOG4108K4B hydrolase EIL75_RS15630 ENOG4105E0C molybdate abc transporter EIL75_RS15635 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EIL75_RS15645 ENOG4105F4R Transcriptional regulator mode EIL75_RS15650 ENOG4105DKW ABC transporter EIL75_RS15660 ENOG4105CMR udp-glucose 4-epimerase EIL75_RS15665 ENOG4105F0Z galactose-1-phosphate uridylyltransferase EIL75_RS15675 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) EIL75_RS15685 ENOG4105E0A ABC, transporter EIL75_RS15690 ENOG4105EHG Permease protein EIL75_RS15695 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase EIL75_RS15700 ENOG4105D9Q decarboxylase (Beta subunit) EIL75_RS15705 ENOG4107QSA Oxaloacetate decarboxylase EIL75_RS15715 ENOG4107QWE )-transporter EIL75_RS15725 ENOG4105C5Q Transcriptional regulator EIL75_RS15735 ENOG4107GFK fumarate EIL75_RS15740 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EIL75_RS15745 ENOG4105JND homeobox protein EIL75_RS15750 ENOG4105PGM cation diffusion facilitator family transporter EIL75_RS15755 ENOG4106Z1T Nicotinamide Mononucleotide Transporter EIL75_RS15790 ENOG4105UFD tol-pal system protein YbgF EIL75_RS15795 ENOG4105KCK Peptidoglycan-associated lipoprotein EIL75_RS15805 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA EIL75_RS15815 ENOG4105E02 MotA TolQ exbB proton channel EIL75_RS15820 ENOG4107YD3 Thioesterase EIL75_RS15825 ENOG4105KJB cyd operon protein YbgE EIL75_RS15835 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EIL75_RS15840 ENOG4105C4M (Ubiquinol oxidase) subunit I EIL75_RS15855 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EIL75_RS15865 ENOG4105C7S Dehydrogenase EIL75_RS15870 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 EIL75_RS15875 ENOG4105E33 succinate dehydrogenase EIL75_RS15880 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) EIL75_RS15885 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein EIL75_RS15890 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit EIL75_RS15895 ENOG4105BZN citrate synthase EIL75_RS15900 ENOG4108KK1 membrane protein AbrB duplication EIL75_RS15910 ENOG4105E7W lamb ycsf family protein EIL75_RS15915 ENOG4107R7A Allophanate hydrolase subunit 2 EIL75_RS15920 ENOG4105P4J Allophanate hydrolase, subunit 1 EIL75_RS15925 ENOG4107QNR UPF0135 protein EIL75_RS15940 ENOG4105CVP deoxyribo-dipyrimidine photolyase EIL75_RS15945 ENOG4105XIQ Protein of unknown function (DUF2517) EIL75_RS15970 ENOG4105C08 Histidine kinase EIL75_RS15975 ENOG4105EEX Two component transcriptional regulator (Winged helix family EIL75_RS15985 ENOG4105CXN decarboxylase EIL75_RS15990 ENOG4105D5Q Arginine ornithine antiporter EIL75_RS16000 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 EIL75_RS16005 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) EIL75_RS16010 ENOG4105EV9 Alpha Beta Hydrolase EIL75_RS16015 ENOG4105NNH LexA regulated protein EIL75_RS16020 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) EIL75_RS16025 ENOG41090R7 Ferric uptake EIL75_RS16030 ENOG4106P55 Transcriptional regulator EIL75_RS16035 ENOG4107EFR Flavocytochrome c EIL75_RS16040 ENOG41079YP Citrate utilization protein b EIL75_RS16045 ENOG4105CSH Transporter EIL75_RS16050 ENOG4105GX6 (LipO)protein EIL75_RS16055 ENOG4105J5J Outer membrane porin EIL75_RS16065 ENOG4105CI1 PTS System EIL75_RS16075 ENOG4105CE4 GlcNAc 6-P deacetylase EIL75_RS16080 ENOG4105E2R ROK family EIL75_RS16085 ENOG4105D4U had-superfamily hydrolase, subfamily iia EIL75_RS16090 ENOG4105CAQ asparagine synthetase EIL75_RS16135 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EIL75_RS16145 ENOG4105C9A Phoh family EIL75_RS16155 ENOG4108JU5 Magnesium and cobalt efflux protein EIL75_RS16160 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) EIL75_RS16165 ENOG4107RP9 extracellular solute-binding protein, family 3 EIL75_RS16170 ENOG4105EAD ABC transporter EIL75_RS16175 ENOG4105DRP amino acid AbC transporter EIL75_RS16180 ENOG4105CDA abc transporter atp-binding protein EIL75_RS16195 ENOG4105F7F Chaperone EIL75_RS16200 ENOG4105QFC Hsc56 co-chaperone of HscC EIL75_RS16205 ENOG41069CF Protein of unknown function (DUF1266) EIL75_RS16210 ENOG4105QFC Hsc56 co-chaperone of HscC EIL75_RS16215 ENOG41069CF Protein of unknown function (DUF1266) EIL75_RS16225 ENOG4107PAI alpha helical protein EIL75_RS16230 ENOG4108JUB Transcriptional regulator EIL75_RS16235 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) EIL75_RS16260 ENOG4105DJF DNA polymerase III, delta' subunit EIL75_RS16265 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) EIL75_RS16270 ENOG4107QZB decarboxylase EIL75_RS16275 ENOG4108TGR phosphatase EIL75_RS16280 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) EIL75_RS16285 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) EIL75_RS16290 ENOG4105CJN penicillin-binding protein EIL75_RS16295 ENOG4105CNI cell division protein FtsW EIL75_RS16300 ENOG4105K6T rare lipoprotein A EIL75_RS16305 ENOG4105DZ1 carboxypeptidase EIL75_RS16310 ENOG4108Z43 UPF0250 protein EIL75_RS16320 ENOG41064T2 transcriptional regulator, lysR family EIL75_RS16340 ENOG4107Z6W Protein CrcB homolog EIL75_RS16355 ENOG4105CEE C4-dicarboxylate transporter EIL75_RS16360 ENOG4106YYS transcriptional regulatory protein EIL75_RS16365 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism EIL75_RS16370 ENOG4105DUA (citrate (pro-3S)-lyase ligase EIL75_RS16375 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) EIL75_RS16380 ENOG4105CI0 Citrate lyase EIL75_RS16385 ENOG4105CHY citrate lyase, alpha EIL75_RS16390 ENOG4105YGP holo-ACP synthase CitX EIL75_RS16400 ENOG4107QPK )-transporter EIL75_RS16405 ENOG4105KTS ribonuclease EIL75_RS16410 ENOG4105NXH GreA GreB family elongation factor EIL75_RS16415 ENOG4105E2A Dehydrogenase EIL75_RS16420 ENOG4108U51 Universal stress protein EIL75_RS16430 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein EIL75_RS16435 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) EIL75_RS16445 ENOG4108JU3 Alkyl hydroperoxide reductase EIL75_RS16450 ENOG4105D3R alkyl hydroperoxide reductase EIL75_RS16455 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase EIL75_RS16465 ENOG4105DQS Transcriptional regulator EIL75_RS16470 ENOG4105BZV Phosphoadenosine phosphosulfate reductase EIL75_RS16475 ENOG4105GTN ParB Domain Protein Nuclease EIL75_RS16480 ENOG4105CHM Aminotransferase EIL75_RS16485 ENOG4107SCQ Iron-containing alcohol dehydrogenase EIL75_RS16490 ENOG4105VCD cytoplasmic protein EIL75_RS16495 ENOG4105D22 carbon starvation protein EIL75_RS16505 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase EIL75_RS16510 ENOG4105WQI isochorismatase EIL75_RS16515 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase EIL75_RS16520 ENOG4105E4F Isochorismate synthase EIL75_RS16525 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein EIL75_RS16530 ENOG4105E8G Major facilitator Superfamily EIL75_RS16535 ENOG4105DQ5 transport system permease protein EIL75_RS16540 ENOG4105TVJ transport system, permease EIL75_RS16545 ENOG4105E0A ABC, transporter EIL75_RS16550 ENOG4108QY5 Ferric enterobactin transport protein EIL75_RS16555 ENOG4105C0W non-ribosomal peptide synthetase EIL75_RS16560 ENOG41085A6 mbth domain-containing protein EIL75_RS16565 ENOG4105E93 esterase EIL75_RS16570 ENOG4107RNH Outer membrane receptor FepA EIL75_RS16575 ENOG4108TSE Transferase EIL75_RS16585 ENOG4105WQ6 Membrane EIL75_RS16590 ENOG4105HFT AraC family transcriptional regulator EIL75_RS16595 ENOG41067SE Tetr family transcriptional regulator EIL75_RS16600 ENOG4105MSB protein, conserved in bacteria EIL75_RS16605 ENOG4108RCM Nitroreductase EIL75_RS16625 ENOG4105F3R pts system mannose fructose sorbose family iid EIL75_RS16635 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine EIL75_RS16640 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EIL75_RS16650 ENOG4105CUY Mechanosensitive ion channel EIL75_RS16655 ENOG4105C85 amino acid EIL75_RS16665 ENOG4108KBJ Inner membrane protein YkgB EIL75_RS16670 ENOG41066GK UPF0379 protein ykgI EIL75_RS16675 ENOG4107QN2 dihydrolipoyl dehydrogenase EIL75_RS16680 ENOG4108K01 transcriptional regulator EIL75_RS16700 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) EIL75_RS16705 ENOG4105CKK Glycosyl transferase, family 2 EIL75_RS16730 ENOG4105CKK Glycosyl transferase, family 2 EIL75_RS16735 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) EIL75_RS16765 ENOG4106KCD HTH_LUXR EIL75_RS16775 ENOG4106721 fimbriae Y protein EIL75_RS16780 ENOG4108Q9V regulatoR EIL75_RS16785 ENOG4108ZI2 Fimbrial protein EIL75_RS16790 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) EIL75_RS16795 ENOG4105CW0 outer membrane usher protein EIL75_RS16800 ENOG4108AF8 Chaperone EIL75_RS16810 ENOG4108WDE Fimbrial protein EIL75_RS16825 ENOG4105WQ3 Rna-binding protein EIL75_RS16830 ENOG4105S2T inner membrane protein YbcI EIL75_RS16850 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EIL75_RS16860 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EIL75_RS16865 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EIL75_RS16870 ENOG4105C5B carbamate kinase EIL75_RS16875 ENOG4105G5A Protein of unknown function (DUF2877) EIL75_RS16880 ENOG4107REC cytoplasmic protein EIL75_RS16885 ENOG4107R1Q Membrane protein FdrA EIL75_RS16890 ENOG4105DG4 malate L-lactate dehydrogenase EIL75_RS16895 ENOG4105CE7 Amidase, hydantoinase carbamoylase family EIL75_RS16900 ENOG4105S0E allantoin catabolism protein EIL75_RS16905 ENOG4105BZW Glycerate kinase EIL75_RS16910 ENOG4105DTE Xanthine uracil vitamin C permease EIL75_RS16920 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease EIL75_RS16930 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EIL75_RS16935 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EIL75_RS16940 ENOG41060W2 glyoxylate carboligase EIL75_RS16965 ENOG4108UMI ABC transporter, permease EIL75_RS16975 ENOG4105D01 (LipO)protein EIL75_RS16985 ENOG4105CV6 ABC transporter, permease EIL75_RS16990 ENOG4108I0Y (ABC) transporter EIL75_RS16995 ENOG4108UJV acyl-CoA thioesterase i EIL75_RS17000 ENOG4105E1F short-chain dehydrogenase reductase EIL75_RS17005 ENOG4107QR8 Thioredoxin EIL75_RS17010 ENOG4105C4B ABC transporter, permease EIL75_RS17015 ENOG41083J0 (ABC) transporter EIL75_RS17020 ENOG4107QX8 SPFH domain, Band 7 family protein EIL75_RS17025 ENOG4105G5H Membrane EIL75_RS17030 ENOG4108Z6Z Transcriptional regulator EIL75_RS17035 ENOG4105C59 p-type ATPase EIL75_RS17045 ENOG4105MBR gumn family EIL75_RS17050 ENOG4108Z66 YbaK ebsC protein EIL75_RS17055 ENOG4105CGH 5'-nucleotidase EIL75_RS17060 ENOG4105EU0 Major facilitator Superfamily EIL75_RS17065 ENOG4105CKD glutathione-regulated potassium-efflux system protein EIL75_RS17070 ENOG4107RE1 Inosine-guanosine kinase EIL75_RS17075 ENOG4105F2M alpha beta hydrolase fold-3 domain protein EIL75_RS17105 ENOG4107QMP dna polymerase iii subunits gamma and tau EIL75_RS17115 ENOG4105WD1 Membrane EIL75_RS17120 ENOG4108URS primosomal replication protein n'' EIL75_RS17125 ENOG4106428 Protein of unknown function (DUF2496) EIL75_RS17130 ENOG4105DNE Transposase EIL75_RS17135 ENOG4105EGS Mechanosensitive ion channel EIL75_RS17140 ENOG4107XI7 Tetr family transcriptional regulator EIL75_RS17145 ENOG4105C1P efflux transporter, rnd family, mfp subunit EIL75_RS17150 ENOG4105BZS acriflavin resistance protein EIL75_RS17155 ENOG4108UKR Biofilm formation regulator YbaJ EIL75_RS17165 ENOG4108UW5 maltose o-acetyltransferase EIL75_RS17170 ENOG4105GSJ Inner membrane protein ylaC EIL75_RS17185 ENOG41066DG (EAL) domain protein EIL75_RS17195 ENOG41080UX Methyltransferase EIL75_RS17200 ENOG4108MNP Glycoprotein polysaccharide metabolism EIL75_RS17205 ENOG4105C29 acyl-CoA thioesterase EIL75_RS17210 ENOG4105BZU Histidine kinase EIL75_RS17215 ENOG4108YZA Nitrogen regulatory protein pii EIL75_RS17220 ENOG4105BZ1 (ABC) transporter EIL75_RS17225 ENOG4105BZ1 (ABC) transporter EIL75_RS17230 ENOG4108XM1 transcriptional regulator AsnC family EIL75_RS17245 ENOG4108NFA extracellular solute-binding protein EIL75_RS17255 ENOG4108TGP Thioesterase superfamily protein EIL75_RS17260 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein EIL75_RS17265 ENOG4105EIN peptidylprolyl cis-trans isomerase EIL75_RS17270 ENOG4105K70 DNA-binding protein EIL75_RS17275 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) EIL75_RS17300 ENOG4105M85 Bola protein EIL75_RS17305 ENOG4105IEY (LipO)protein EIL75_RS17310 ENOG4105EYM Major Facilitator superfamily EIL75_RS17315 ENOG4105E2S oxidase) subunit II EIL75_RS17320 ENOG4105BZ9 Cytochrome C oxidase, subunit I EIL75_RS17325 ENOG4105CCU oxidase (Subunit III) EIL75_RS17330 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) EIL75_RS17350 ENOG4107RDB Major Facilitator EIL75_RS17360 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) EIL75_RS17365 ENOG4107S0N DJ-1 family EIL75_RS17380 ENOG4106S9K Transcriptional regulator EIL75_RS17390 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EIL75_RS17395 ENOG4108MP3 ABC transporter, permease EIL75_RS17400 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component EIL75_RS17410 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) EIL75_RS17415 ENOG4105CTB Polyprenyl synthetase EIL75_RS17425 ENOG4105CPC Aldo Keto reductase EIL75_RS17430 ENOG4108ZAI phosphatidylglycerophosphatase a EIL75_RS17435 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) EIL75_RS17440 ENOG4107YIM Involved in the transcription termination process (By similarity) EIL75_RS17450 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EIL75_RS17460 ENOG4108KIC (LipO)protein EIL75_RS17465 ENOG4105DRB nucleoside-specific channel-forming protein EIL75_RS17480 ENOG4105N1F Hnh endonuclease EIL75_RS17485 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EIL75_RS17495 ENOG4105VIE preprotein translocase, subunit YajC EIL75_RS17515 ENOG4105D3R alkyl hydroperoxide reductase EIL75_RS17525 ENOG4107R28 alpha amylase, catalytic region EIL75_RS17530 ENOG4105C85 amino acid EIL75_RS17535 ENOG4105CWM branched-chain amino acid transport system II carrier protein EIL75_RS17540 ENOG4105BZU Histidine kinase EIL75_RS17545 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EIL75_RS17550 ENOG4107RH8 nuclease SbcCD subunit D EIL75_RS17555 ENOG4105EYH Exonuclease EIL75_RS17560 ENOG4105F27 Major Facilitator EIL75_RS17565 ENOG4105DKQ ROK family EIL75_RS17580 ENOG4105HBA AroM protein EIL75_RS17585 ENOG4105SS3 EIL75_RS17600 ENOG4105II7 pyrroline-5-carboxylate reductase EIL75_RS17605 ENOG4105BZU Histidine kinase EIL75_RS17610 ENOG4105VIF phosphate starvation-inducible protein EIL75_RS17630 ENOG4105CPF Cell wall formation (By similarity) EIL75_RS17635 ENOG4105UNH Membrane EIL75_RS17640 ENOG4105FR5 inner membrane protein YaiY EIL75_RS17645 ENOG4107QS8 (LipO)protein EIL75_RS17650 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 EIL75_RS17660 ENOG4107R6D beta-lactam binding protein AmpH EIL75_RS17665 ENOG4108PNB DNA-binding transcriptional regulator EIL75_RS17670 ENOG4108NSE outer membrane autotransporter barrel EIL75_RS17675 ENOG4105D52 delta-aminolevulinic acid dehydratase EIL75_RS17680 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EIL75_RS17685 ENOG4105DXD 2-methylcitrate dehydratase EIL75_RS17690 ENOG4105BZN citrate synthase EIL75_RS17695 ENOG4105CR4 methylisocitrate lyase EIL75_RS17700 ENOG4108JU7 Transcriptional regulator EIL75_RS17705 ENOG4105TDT uncharacterized protein yahO EIL75_RS17710 ENOG4105E82 cytochrome subunit of dehydrogenase EIL75_RS17730 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EIL75_RS17735 ENOG4105C4M (Ubiquinol oxidase) subunit I EIL75_RS17745 ENOG4105D8D Type III EIL75_RS17750 ENOG4107QMH DNA methylase EIL75_RS17755 ENOG4105JHE Major Facilitator Superfamily EIL75_RS17775 ENOG4105C1P efflux transporter, rnd family, mfp subunit EIL75_RS17785 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EIL75_RS17805 ENOG4108T1M outer membrane protein x EIL75_RS17820 ENOG4105CXC rtn protein EIL75_RS17835 ENOG4105X0I Fimbrial EIL75_RS17840 ENOG4108VEV chaperone EIL75_RS17845 ENOG4105CW0 outer membrane usher protein EIL75_RS17880 ENOG4105FCK Membrane EIL75_RS17895 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) EIL75_RS17900 ENOG4105CIN aminoacyl-histidine dipeptidase EIL75_RS17905 ENOG4108S2Y peptide Chain Release factor EIL75_RS17920 ENOG4105F7V ErfK ybiS ycfS ynhG family protein EIL75_RS17925 ENOG4105E7A Glutamine amidotransferase EIL75_RS17935 ENOG4107QPN acyl-Coa dehydrogenase EIL75_RS17940 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase EIL75_RS17950 ENOG4105T40 surface antigen msp4 family protein EIL75_RS17960 ENOG4105W7K Transcriptional regulator EIL75_RS18095 ENOG4105CNA YD repeat protein EIL75_RS18105 ENOG4105CS6 Rhs element vgr protein EIL75_RS18220 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EIL75_RS18265 ENOG4107RZZ dna polymerase iii epsilon subunit EIL75_RS18270 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) EIL75_RS18275 ENOG4105D1A Methyltransferase EIL75_RS18285 ENOG4105E9H Lytic Murein transglycosylase EIL75_RS18290 ENOG4105F2W methyltransferase EIL75_RS18300 ENOG4105F27 Major Facilitator EIL75_RS18305 ENOG4105HEI LysR family (Transcriptional regulator EIL75_RS18310 ENOG4105CV8 reductase EIL75_RS18345 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase EIL75_RS18350 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EIL75_RS18355 ENOG4108UMI ABC transporter, permease EIL75_RS18360 ENOG4105D01 (LipO)protein EIL75_RS18365 ENOG4108R8X outer membrane lipoprotein EIL75_RS18370 ENOG4108R96 Methyltransferase, YaeB family EIL75_RS18380 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion EIL75_RS18385 ENOG4108YZN class I peptide chain release factor EIL75_RS18390 ENOG4108VWS Yaeq family EIL75_RS18400 ENOG4105M1T rho-binding antiterminator EIL75_RS18410 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase EIL75_RS18415 ENOG4105CXN decarboxylase EIL75_RS18420 ENOG4108M1A Chitin-binding protein EIL75_RS18430 ENOG4105C0B DNA polymerase III (alpha subunit) EIL75_RS18450 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) EIL75_RS18455 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EIL75_RS18460 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) EIL75_RS18475 ENOG4105KNE Phosphatidate cytidylyltransferase EIL75_RS18490 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) EIL75_RS18495 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) EIL75_RS18505 ENOG4105CE9 30S ribosomal protein S2 EIL75_RS18510 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EIL75_RS18525 ENOG4105CSH Transporter EIL75_RS18535 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR EIL75_RS18540 ENOG4105C0H protease EIL75_RS18555 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) EIL75_RS18560 ENOG4105EN6 Membrane EIL75_RS18565 ENOG4108YX9 iron--sulfur cluster insertion protein erpA EIL75_RS18580 ENOG4106RDH Protein of unknown function (DUF2544) EIL75_RS18590 ENOG4105UGQ Fimbrial EIL75_RS18595 ENOG4105NEV Fimbrial EIL75_RS18600 ENOG4108FZ9 Chaperone EIL75_RS18605 ENOG4106PG1 outer membrane usher protein EIL75_RS18620 ENOG4105S6R Iron-hydroxamate transporter permease subunit EIL75_RS18625 ENOG4105J76 Periplasmic binding protein EIL75_RS18630 ENOG4105E0A ABC, transporter EIL75_RS18635 ENOG4105E0K tonB-dependent siderophore receptor EIL75_RS18640 ENOG4105BZ4 penicillin-binding protein EIL75_RS18645 ENOG4105CQ7 ATP-dependent helicase EIL75_RS18650 ENOG4107XID 2'-5' rna ligase EIL75_RS18660 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters EIL75_RS18670 ENOG4105DJ0 Poly(A) Polymerase EIL75_RS18675 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EIL75_RS18700 ENOG4108VEV chaperone EIL75_RS18705 ENOG4105CW0 outer membrane usher protein EIL75_RS18710 ENOG4108XEY fimbrial-like adhesin protein EIL75_RS18730 ENOG4107BJW polysaccharide deacetylase EIL75_RS18735 ENOG4108YTN IIa component EIL75_RS18745 ENOG4108UIF Chaperone EIL75_RS18750 ENOG4105CW0 outer membrane usher protein EIL75_RS18755 ENOG4108MDY Fimbrial EIL75_RS18760 ENOG4105E3A (ABC) transporter EIL75_RS18765 ENOG4105DA5 (ABC) transporter EIL75_RS18770 ENOG41077A9 carbonic anhydrase EIL75_RS18775 ENOG4108UGV hypoxanthine phosphoribosyltransferase EIL75_RS18780 ENOG4105DZG Dehydrogenase EIL75_RS18785 ENOG4105E3B Multicopper oxidase EIL75_RS18790 ENOG4108ZRK uncharacterized protein yacC EIL75_RS18805 ENOG4105MVE transcriptional regulator EIL75_RS18810 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) EIL75_RS18815 ENOG4107S2N Type III effector Hrp-dependent EIL75_RS18820 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) EIL75_RS18835 ENOG4106HGK Inner membrane protein yieI EIL75_RS18840 ENOG4107QIJ Aconitate hydratase 2 EIL75_RS18845 ENOG4108NST exported protein EIL75_RS18860 ENOG4107QN2 dihydrolipoyl dehydrogenase EIL75_RS18865 ENOG4107QSN dihydrolipoamide acetyltransferase EIL75_RS18870 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) EIL75_RS18885 ENOG4105CT4 transporter EIL75_RS18890 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) EIL75_RS18895 ENOG4106A72 regulatory protein AmpE EIL75_RS18905 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EIL75_RS18915 ENOG4108ZUW Major pilin subunit EIL75_RS18920 ENOG4107QHF type ii secretion system protein e EIL75_RS18925 ENOG4105D7Q type ii secretion system EIL75_RS18935 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EIL75_RS18955 ENOG4105M6F mutator MutT protein EIL75_RS18975 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EIL75_RS18980 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EIL75_RS18985 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) EIL75_RS19005 ENOG4105CNI cell division protein FtsW EIL75_RS19015 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) EIL75_RS19020 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) EIL75_RS19025 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EIL75_RS19030 ENOG4105CJN penicillin-binding protein EIL75_RS19035 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) EIL75_RS19050 ENOG4107B7Y DNA-binding transcriptional regulator FruR EIL75_RS19055 ENOG4108ZP8 Acetolactate synthase small subunit EIL75_RS19060 ENOG4105C7K acetolactate synthase EIL75_RS19065 ENOG41064T2 transcriptional regulator, lysR family EIL75_RS19090 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) EIL75_RS19115 ENOG4107T0D ABC, transporter EIL75_RS19120 ENOG4108KF1 Membrane EIL75_RS19125 ENOG41063TF transcriptional regulator (AraC EIL75_RS19130 ENOG4105EF1 ribulokinase EIL75_RS19140 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase EIL75_RS19160 ENOG4105CQ2 DNA polymerase EIL75_RS19170 ENOG4105D3G Pseudouridine synthase EIL75_RS19180 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) EIL75_RS19190 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) EIL75_RS19200 ENOG4105NWN ApaG protein EIL75_RS19250 ENOG4105M5B (LipO)protein EIL75_RS19255 ENOG4105C54 Major Facilitator superfamily EIL75_RS19260 ENOG4105WQV ferredoxin-like protein EIL75_RS19265 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase EIL75_RS19290 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F EIL75_RS19310 ENOG4108XNW Transcriptional activatory protein CaiF EIL75_RS19315 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain EIL75_RS19320 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain EIL75_RS19350 ENOG4105CHY citrate lyase, alpha EIL75_RS19355 ENOG4105CI0 Citrate lyase EIL75_RS19365 ENOG4105DUA (citrate (pro-3S)-lyase ligase EIL75_RS19370 ENOG4105D2K citrate carrier protein EIL75_RS19380 ENOG4107QSA Oxaloacetate decarboxylase EIL75_RS19385 ENOG4105D9Q decarboxylase (Beta subunit) EIL75_RS19390 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism EIL75_RS19395 ENOG4106YYS transcriptional regulatory protein EIL75_RS19415 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase EIL75_RS19425 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) EIL75_RS19430 ENOG4105DTN riboflavin biosynthesis protein ribF EIL75_RS19435 ENOG410647N response to DNA damage stimulus EIL75_RS19455 ENOG41063Z6 transcriptional regulator, lysR family EIL75_RS19480 ENOG4105C4X radical SAM domain protein EIL75_RS19485 ENOG41061MV Arylsulfatase EIL75_RS19520 ENOG4106PH7 chaperone EIL75_RS19535 ENOG4105MHR Fimbrial protein EIL75_RS19540 ENOG4105CW0 outer membrane usher protein EIL75_RS19545 ENOG4108AF8 Chaperone EIL75_RS19605 ENOG4108QUJ UPF0174 protein YaaW EIL75_RS19610 ENOG4106HK8 GPR1 FUN34 yaaH family protein EIL75_RS19615 ENOG4108RIR Molybdenum cofactor biosynthesis protein EIL75_RS19620 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EIL75_RS19625 ENOG4105BZG amino acid carrier protein EIL75_RS19635 ENOG4105D98 threonine synthase EIL75_RS19645 ENOG4105CFH Aspartokinase EIL75_RS19655 ENOG4106FVC RNA methyltransferase EIL75_RS19660 ENOG410759A EIL75_RS19665 ENOG41065U4 response regulator EIL75_RS19675 ENOG4108PNB DNA-binding transcriptional regulator EIL75_RS19685 ENOG4108VCD Chaperone EIL75_RS19690 ENOG4105CW0 outer membrane usher protein EIL75_RS19705 ENOG4105CT7 inner membrane cred family protein EIL75_RS19710 ENOG4105EB3 Histidine kinase EIL75_RS19715 ENOG4105E3W Two component transcriptional regulator (Winged helix family EIL75_RS19720 ENOG4108RH0 Crea protein EIL75_RS19725 ENOG4105UEI Transcriptional Regulator AraC Family EIL75_RS19750 ENOG4107SC1 transglycosylase EIL75_RS19755 ENOG4105C5H ABC transporter EIL75_RS19760 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase EIL75_RS19765 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EIL75_RS19770 ENOG4105EAC phosphoserine phosphatase EIL75_RS19780 ENOG41062Z9 Membrane EIL75_RS19795 ENOG4105UMR response to DNA damage stimulus EIL75_RS19800 ENOG4108S1B Periplasmic chaperone protein EIL75_RS19805 ENOG4105E6S usher protein( EIL75_RS19835 ENOG4105G0K glycine radical enzyme YjjI family EIL75_RS19840 ENOG41076CZ activating enzyme EIL75_RS19845 ENOG4105EYA deoxyribonuclease EIL75_RS19850 ENOG4108NRW Phospholipase, patatin family EIL75_RS19860 ENOG4105K3G Periplasmic Protein EIL75_RS19870 ENOG4105PAD Hydrolase EIL75_RS19875 ENOG4105KEG ribosomal-protein-alanine acetyltransferase EIL75_RS19880 ENOG4108WPU DNA polymerase III subunit psi EIL75_RS19905 ENOG4105YBH Protein of unknown function (DUF1435) EIL75_RS19910 ENOG4105BZU Histidine kinase EIL75_RS19915 ENOG4108819 ferric iron reductase EIL75_RS19920 ENOG4108UIN ybak prolyl-trna synthetase associated region EIL75_RS19925 ENOG4108T94 DNA-binding transcriptional activator BglJ EIL75_RS19930 ENOG4108N8T regulatoR EIL75_RS19935 ENOG4105DWK Membrane EIL75_RS19950 ENOG4106CVF DNA replication protein EIL75_RS19955 ENOG4105RI1 glycoprotein receptor EIL75_RS19965 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EIL75_RS19970 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EIL75_RS19975 ENOG4105F3R pts system mannose fructose sorbose family iid EIL75_RS19980 ENOG4105ETZ PTS System EIL75_RS19985 ENOG4108IQ3 PTS system EIL75_RS20005 ENOG4105C8Q Methyl-accepting chemotaxis EIL75_RS20010 ENOG4105D22 carbon starvation protein EIL75_RS20015 ENOG4105VCD cytoplasmic protein EIL75_RS20020 ENOG4105CKI cobalamin synthesis protein EIL75_RS20030 ENOG4108F3G Type I restriction-modification system, R subunit EIL75_RS20040 ENOG4107QTH restriction modification system DNA specificity domain EIL75_RS20055 ENOG4108HFV EIL75_RS20070 ENOG4105C26 Dehydrogenase EIL75_RS20075 ENOG4105DNE Transposase EIL75_RS20080 ENOG41083G8 Multidrug resistance protein MdtM EIL75_RS20085 ENOG4106BRA Membrane EIL75_RS20090 ENOG4105CBP Major Facilitator EIL75_RS20100 ENOG41074DU domain protein EIL75_RS20105 ENOG4108P2H Inner membrane protein YjiG EIL75_RS20110 ENOG4105DYB Isoaspartyl dipeptidase EIL75_RS20115 ENOG4107YNJ LysR family Transcriptional regulator EIL75_RS20140 ENOG4105C6F GntR Family Transcriptional Regulator EIL75_RS20165 ENOG4105KZM cytoplasmic protein EIL75_RS20180 ENOG4105DTA methyltransferase EIL75_RS20200 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase EIL75_RS20235 ENOG4105C9U ATP-dependent DNA helicase RecQ EIL75_RS20240 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) EIL75_RS20300 ENOG4105DQ4 alcohol dehydrogenase EIL75_RS20305 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EIL75_RS20310 ENOG4105CPQ Dehydrogenase EIL75_RS20315 ENOG4105CHR reductase EIL75_RS20320 ENOG4105C6Z Gluconate EIL75_RS20325 ENOG4105K2J Transcriptional regulator EIL75_RS20330 ENOG4108K5H permease YjgP YjgQ family protein EIL75_RS20335 ENOG4108M8S permease YjgP YjgQ family protein EIL75_RS20350 ENOG4105MYG DNA polymerase iii, chi subunit EIL75_RS20355 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) EIL75_RS20360 ENOG4108M3P Membrane EIL75_RS20365 ENOG4108MJ3 acetyltransferase EIL75_RS20375 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase EIL75_RS20380 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) EIL75_RS20385 ENOG4105DBV ornithine carbamoyltransferase EIL75_RS20390 ENOG4105XEP YhcH YjgK YiaL family protein EIL75_RS20405 ENOG4105C5B carbamate kinase EIL75_RS20410 ENOG4105DBV ornithine carbamoyltransferase EIL75_RS20415 ENOG4105CSX c4-dicarboxylate anaerobic carrier EIL75_RS20420 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) EIL75_RS20430 ENOG41077AM PyrBI operon attenuator EIL75_RS20445 ENOG4105KME endoribonuclease L-psp EIL75_RS20465 ENOG4105D4X repressor EIL75_RS20470 ENOG4105C5Y PTS System EIL75_RS20475 ENOG4105CG3 alpha amylase, catalytic region EIL75_RS20480 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase EIL75_RS20485 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) EIL75_RS20490 ENOG4105K4U addiction module toxin, RelE StbE family EIL75_RS20500 ENOG4105EMD TRANSCRIPTIONal EIL75_RS20515 ENOG41069H0 dihydroorotase EC 3.5.2.3 EIL75_RS20545 ENOG4108XVM Cytochrome b(562) EIL75_RS20550 ENOG4105CMS peptidase U62, modulator of DNA gyrase EIL75_RS20560 ENOG4105F0H myo-inositol catabolism protein EIL75_RS20570 ENOG4105IE8 Alpha-ketoglutarate permease EIL75_RS20575 ENOG4105CK5 oxidoreductase EIL75_RS20580 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) EIL75_RS20585 ENOG4105D7K pfkb domain protein EIL75_RS20595 ENOG4107VG4 Xylose isomerase domain protein TIM barrel EIL75_RS20600 ENOG4108MYR Secreted protein EIL75_RS20625 ENOG4105C26 Dehydrogenase EIL75_RS20630 ENOG4105DH8 myo-inositol catabolism EIL75_RS20635 ENOG4107QNK )-transporter EIL75_RS20645 ENOG4107QNK )-transporter EIL75_RS20650 ENOG4105CHC glucokinase (EC 2.7.1.2) EIL75_RS20660 ENOG4105DFU Cell wall formation (By similarity) EIL75_RS20670 ENOG4105F0N pyrophosphate phospho-hydrolase EIL75_RS20675 ENOG41069H0 dihydroorotase EC 3.5.2.3 EIL75_RS20680 ENOG4105DJB Major Facilitator Superfamily EIL75_RS20685 ENOG4108ZHD aig2 family EIL75_RS20705 ENOG4105C37 (CBS) domain EIL75_RS20710 ENOG41061GZ Protein of unknown function (DUF1107) EIL75_RS20720 ENOG4108UUE Transcriptional regulator EIL75_RS20725 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase EIL75_RS20735 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic EIL75_RS20740 ENOG4105KVH Transcriptional regulator EIL75_RS20745 ENOG4105ECR NmrA family EIL75_RS20750 ENOG4105DXC membrane EIL75_RS20765 ENOG4108V1T peptidylprolyl cis-trans isomerase EIL75_RS20770 ENOG4105FHY Opacity-associated protein A EIL75_RS20780 ENOG4105K9Q Binds to the 23S rRNA (By similarity) EIL75_RS20785 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) EIL75_RS20790 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) EIL75_RS20795 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) EIL75_RS20810 ENOG4105KIT UPF0379 protein yjfY EIL75_RS20840 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC EIL75_RS20855 ENOG4108MXZ Esterase EIL75_RS20860 ENOG4105WSB biofilm stress and motility protein A EIL75_RS20865 ENOG4105S17 UPF0379 protein yjfN EIL75_RS20870 ENOG4105CSU acyl-Coa dehydrogenase EIL75_RS20875 ENOG4106032 Glutathionylspermidine synthase EIL75_RS20880 ENOG4108KXT Conserved Protein EIL75_RS20885 ENOG4105Z6B inner membrane protein yjfl EIL75_RS20890 ENOG4107VNS Protein of unknown function (DUF2491) EIL75_RS20900 ENOG4108P9J Phage shock protein A EIL75_RS20905 ENOG4105FUX Conserved Protein EIL75_RS20910 ENOG4105C2N RNA methyltransferase TrmH family group 3 EIL75_RS20915 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EIL75_RS20940 ENOG4105EPW hflc protein EIL75_RS20945 ENOG4107QJR hflk protein EIL75_RS20950 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EIL75_RS20955 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) EIL75_RS20970 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase EIL75_RS20975 ENOG4105K8N protein family UPF0079, ATPase EIL75_RS20980 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) EIL75_RS20985 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EIL75_RS21005 ENOG4106TNF Periplasmic binding protein EIL75_RS21010 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) EIL75_RS21025 ENOG4105EGS Mechanosensitive ion channel EIL75_RS21030 ENOG4106CG8 Inner membrane protein YjeO EIL75_RS21035 ENOG4107SC7 Inner membrane transporter yjeM EIL75_RS21045 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) EIL75_RS21050 ENOG4105E33 succinate dehydrogenase EIL75_RS21060 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) EIL75_RS21070 ENOG4105KPY Small multidrug resistance protein EIL75_RS21080 ENOG4106BSU Entericidin B EIL75_RS21095 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) EIL75_RS21100 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein EIL75_RS21105 ENOG4105MTB Uncharacterized protein YjeJ EIL75_RS21110 ENOG4108ZVF (LipO)protein EIL75_RS21125 ENOG4105DVH amino acid EIL75_RS21130 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 EIL75_RS21135 ENOG4108IJ0 Aspartate ammonia-lyase EIL75_RS21140 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter EIL75_RS21155 ENOG4108SIC Transcriptional regulator EIL75_RS21170 ENOG4105SBG acid phosphatase EIL75_RS21190 ENOG4108Z33 Thiol disulfide Interchange Protein EIL75_RS21255 ENOG41068CG regulatoR EIL75_RS21270 ENOG4108ZK4 sdia-regulated domain-containing protein EIL75_RS21280 ENOG4108NEM leader-binding protein dmsD EIL75_RS21285 ENOG4107KGK dmso reductase anchor subunit EIL75_RS21290 ENOG4105QAX Iron-sulfur EIL75_RS21295 ENOG4107QY8 reductase EIL75_RS21300 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism EIL75_RS21305 ENOG4108MRH transcriptional regulatory protein EIL75_RS21315 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter EIL75_RS21320 ENOG4107GFK fumarate EIL75_RS21325 ENOG4105CT4 transporter EIL75_RS21330 ENOG4105F8D glycoside hydrolase family 4 EIL75_RS21335 ENOG4108K2B transcriptional regulator EIL75_RS21340 ENOG4105CXN decarboxylase EIL75_RS21345 ENOG4106ZGR Transcriptional regulator EIL75_RS21350 ENOG4105D5Q Arginine ornithine antiporter EIL75_RS21355 ENOG4105DIJ Phosphoethanolamine transferase EIL75_RS21360 ENOG4105XJC Two component transcriptional regulator (Winged helix family EIL75_RS21365 ENOG4105ECM Sensor protein basS pmrB EIL75_RS21375 ENOG4105CSH Transporter EIL75_RS21380 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EIL75_RS21385 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase EIL75_RS21390 ENOG410870W N-acetyltransferase EIL75_RS21405 ENOG41082ND Uncharacterized protein yjcO EIL75_RS21410 ENOG4105CK2 sodium dicarboxylate symporter EIL75_RS21415 ENOG4108W0S formate-dependent nitrite reductase complex EIL75_RS21420 ENOG4108QKW cytochrome c-type biogenesis protein EIL75_RS21425 ENOG4105DVI reductase, NrfD EIL75_RS21430 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein EIL75_RS21435 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit EIL75_RS21445 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EIL75_RS21450 ENOG41062QD Membrane EIL75_RS21460 ENOG41067MG lrgb family EIL75_RS21470 ENOG4105CMU LysR family (Transcriptional regulator EIL75_RS21475 ENOG4105EEQ Na H antiporter EIL75_RS21485 ENOG4105C7N Xanthine uracil vitamin C permease EIL75_RS21495 ENOG4108Z4X TRANSCRIPTIONal EIL75_RS21500 ENOG4108W3Q Transcriptional regulator EIL75_RS21505 ENOG4108M8H domain protein EIL75_RS21510 ENOG4105PMV Membrane EIL75_RS21545 ENOG4108UUM single-stranded DNA-binding protein EIL75_RS21555 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EIL75_RS21570 ENOG4105MSB protein, conserved in bacteria EIL75_RS21575 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme EIL75_RS21580 ENOG4105F0S class B acid phosphatase EIL75_RS21585 ENOG4105CGF Aromatic amino acid aminotransferase EIL75_RS21590 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EIL75_RS21595 ENOG4105CDU Replicative dna helicase EIL75_RS21600 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein EIL75_RS21605 ENOG4105P4Z Phage shock protein G EIL75_RS21610 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EIL75_RS21620 ENOG4105MYN Zinc uptake regulation protein EIL75_RS21625 ENOG4105VDW Csbd family EIL75_RS21635 ENOG4107R73 Mate efflux family protein EIL75_RS21640 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) EIL75_RS21645 ENOG41080IJ Diacylglycerol kinase EIL75_RS21665 ENOG4107W52 maltose operon periplasmic protein EIL75_RS21675 ENOG4108IJ9 (ABC) transporter EIL75_RS21680 ENOG4107FKK extracellular solute-binding protein family 1 EIL75_RS21685 ENOG4105D56 permease protein EIL75_RS21690 ENOG4105EG2 ABC transporter, permease EIL75_RS21700 ENOG4105E3R (LipO)protein EIL75_RS21705 ENOG4108Q9C Periplasmic Protein EIL75_RS21710 ENOG4108MDC (LipO)protein EIL75_RS21725 ENOG4105CFH Aspartokinase EIL75_RS21810 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) EIL75_RS21815 ENOG4105CKK Glycosyl transferase, family 2 EIL75_RS21840 ENOG4108X9F tail fiber protein EIL75_RS21865 ENOG4105C09 Bile acid EIL75_RS21870 ENOG4108ZR5 Conserved Protein EIL75_RS21875 ENOG4105FE9 pseudouridine synthase EIL75_RS21880 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme EIL75_RS21895 ENOG4105EAM Na Pi-cotransporter EIL75_RS21900 ENOG4105C3R Methionine synthase EIL75_RS21905 ENOG41069M3 Transcriptional regulator EIL75_RS21920 ENOG4108I9X Isocitrate lyase EIL75_RS21925 ENOG4107QP3 malate synthase g EIL75_RS21935 ENOG4105K5X acetyltransferase EIL75_RS21965 ENOG4105C12 Phosphoribosylglycinamide synthetase EIL75_RS21970 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EIL75_RS21975 ENOG4105BZU Histidine kinase EIL75_RS21985 ENOG4108T8B Protein of unknown function (DUF1481) EIL75_RS21990 ENOG4105K70 DNA-binding protein EIL75_RS21995 ENOG4105R2J Conserved Protein EIL75_RS22030 ENOG4105D06 uba thif-type nad fad binding protein EIL75_RS22035 ENOG4105WHD thiamine biosynthesis protein ThiS EIL75_RS22045 ENOG4105D41 biosynthesis protein thiH EIL75_RS22070 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) EIL75_RS22075 ENOG4107QIH DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) EIL75_RS22080 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) EIL75_RS22085 ENOG4108VZM 50s ribosomal protein L10 EIL75_RS22100 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EIL75_RS22105 ENOG4105PM1 preprotein translocase subunit SecE EIL75_RS22110 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) EIL75_RS22145 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase EIL75_RS22150 ENOG4105D4A Cell wall formation (By similarity) EIL75_RS22195 ENOG4108Y73 Membrane EIL75_RS22210 ENOG4105C5Q Transcriptional regulator EIL75_RS22250 ENOG4105DIJ Phosphoethanolamine transferase EIL75_RS22255 ENOG4106R3P AraC family transcriptional regulator EIL75_RS22265 ENOG4105DCT glycerol dehydrogenase EIL75_RS22270 ENOG4108XC3 NADH ubiquinone oxidoreductase EIL75_RS22280 ENOG4105SYT Methylenetetrahydrofolate reductase EIL75_RS22285 ENOG4105CGH 5'-nucleotidase EIL75_RS22300 ENOG4105D64 Mechanosensitive ion channel EIL75_RS22305 ENOG4105CFH Aspartokinase EIL75_RS22310 ENOG4105C28 cystathionine EIL75_RS22320 ENOG4108MR7 Arylsulfotransferase EIL75_RS22335 ENOG4105C25 Primosomal protein n' EIL75_RS22340 ENOG4105ETE Transcriptional regulator (LacI family EIL75_RS22345 ENOG41063M6 Cell Division Protein EIL75_RS22360 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase EIL75_RS22375 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) EIL75_RS22385 ENOG4105CBT Fructose-1,6-bisphosphatase EIL75_RS22390 ENOG4105DP0 ferredoxin-NADP reductase EIL75_RS22395 ENOG4108VTS Membrane EIL75_RS22400 ENOG4105EBK exported protein EIL75_RS22425 ENOG4105D4B ABC, transporter EIL75_RS22450 ENOG4107RYS Autoinducer-2 (AI-2) kinase EIL75_RS22460 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) EIL75_RS22480 ENOG4105D7K pfkb domain protein EIL75_RS22485 ENOG4105CT4 transporter EIL75_RS22495 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EIL75_RS22500 ENOG4105CTQ phosphohexokinase EIL75_RS22510 ENOG4105FMW periplasmic EIL75_RS22515 ENOG4105E3W Two component transcriptional regulator (Winged helix family EIL75_RS22520 ENOG4105E0F Histidine kinase EIL75_RS22530 ENOG4108RPX mosc domain containing protein EIL75_RS22535 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EIL75_RS22540 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit EIL75_RS22545 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter EIL75_RS22550 ENOG4105CG6 trap dicarboxylate transporter dctm subunit EIL75_RS22555 ENOG4108QGT oligogalacturonate-specific porin EIL75_RS22590 ENOG4105C0A alcohol dehydrogenase EIL75_RS22605 ENOG4108UMN azlc family EIL75_RS22615 ENOG4108V87 frv operon regulatory protein EIL75_RS22620 ENOG4108V87 frv operon regulatory protein EIL75_RS22640 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein EIL75_RS22645 ENOG4108MG3 formate dehydrogenase EIL75_RS22660 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system EIL75_RS22670 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) EIL75_RS22675 ENOG4108Z3N Transcriptional regulator EIL75_RS22680 ENOG4105SUU thioesterase domain EIL75_RS22695 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 EIL75_RS22700 ENOG4105E98 transcriptional regulator DeoR family EIL75_RS22705 ENOG4108MGF sugar kinase EIL75_RS22710 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EIL75_RS22715 ENOG4105D2M Aldolase EIL75_RS22720 ENOG4107QKS N-acylglucosamine 2-epimerase EIL75_RS22725 ENOG4107WI4 Aldose-1-epimerase EIL75_RS22730 ENOG4105CJQ hydrolase, family 31 EIL75_RS22735 ENOG4105CT4 transporter EIL75_RS22740 ENOG4105CT4 transporter EIL75_RS22745 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is EIL75_RS22775 ENOG4108K4B hydrolase EIL75_RS22780 ENOG4105CI3 gtp-binding protein typa EIL75_RS22785 ENOG4105C5F glutamine synthetase EIL75_RS22790 ENOG4105CUX Signal transduction histidine kinase EIL75_RS22795 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EIL75_RS22800 ENOG4106FIY EIL75_RS22805 ENOG4105D4P Coproporphyrinogen iii oxidase EIL75_RS22825 ENOG4105C2M dna polymerase I EIL75_RS22835 ENOG4106HNH Acyl-transferase EIL75_RS22840 ENOG4108Z33 Thiol disulfide Interchange Protein EIL75_RS22850 ENOG4105PC1 Conserved Protein EIL75_RS22855 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) EIL75_RS22860 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b EIL75_RS22890 ENOG4108RR8 protoporphyrinogen oxidase EIL75_RS22895 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) EIL75_RS22900 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein EIL75_RS22915 ENOG4105CHU acetyl-coa acetyltransferase EIL75_RS22920 ENOG4108MR7 Arylsulfotransferase EIL75_RS22925 ENOG4107QK7 reductase EIL75_RS22930 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) EIL75_RS22935 ENOG4105MDZ Transcriptional activator rfaH EIL75_RS22940 ENOG4105F8V Hydrolase, tatD family EIL75_RS22945 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) EIL75_RS22950 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) EIL75_RS22955 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) EIL75_RS22965 ENOG4105JC1 sterol-binding domain protein EIL75_RS22975 ENOG4105CGY Dna recombination protein EIL75_RS22980 ENOG4107SXA Phosphorylase EIL75_RS22985 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) EIL75_RS22990 ENOG4105C4X radical SAM domain protein EIL75_RS23005 ENOG4105DZ2 Transcriptional regulator EIL75_RS23010 ENOG4105EMK carboxylate amino acid amine transporter EIL75_RS23015 ENOG4105DQF Hydrolase EIL75_RS23020 ENOG4108EUD Lysophospholipase EIL75_RS23025 ENOG410829K Lysine exporter protein (Lyse ygga) EIL75_RS23030 ENOG4105CCF Lysine exporter protein (Lyse ygga) EIL75_RS23035 ENOG4105C9U ATP-dependent DNA helicase RecQ EIL75_RS23040 ENOG4105HDD phospholipase EIL75_RS23045 ENOG4108VUY thioesterase Superfamily protein EIL75_RS23050 ENOG4105FR1 rard protein EIL75_RS23055 ENOG4106WR8 Inner membrane protein YigG EIL75_RS23060 ENOG4105NRM Membrane EIL75_RS23065 ENOG4107QUT magnesium and cobalt transport protein CorA EIL75_RS23075 ENOG4105C4R Atp-dependent dna helicase EIL75_RS23080 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant EIL75_RS23085 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EIL75_RS23090 ENOG4105CT0 Protein of unknown function, DUF484 EIL75_RS23100 ENOG4105S7Z (LipO)protein EIL75_RS23120 ENOG4107T0K Adenylate cyclase EIL75_RS23130 ENOG41076E6 Uroporphyrinogen-III Synthase EIL75_RS23135 ENOG4105ECF c-methyltransferase EIL75_RS23140 ENOG410601J HemY protein EIL75_RS23165 ENOG4105C85 amino acid EIL75_RS23180 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) EIL75_RS23185 ENOG4105EGZ biosynthesis protein EIL75_RS23190 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EIL75_RS23195 ENOG4108WJ1 acetyltransferase EIL75_RS23200 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) EIL75_RS23205 ENOG4105C1B dTDP-glucose 4-6-dehydratase EIL75_RS23210 ENOG4108IJ1 Dehydrogenase EIL75_RS23215 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase EIL75_RS23220 ENOG4105SFE lipopolysaccharide biosynthesis protein EIL75_RS23225 ENOG4105ESV Glycosyl transferase, family 4 EIL75_RS23235 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) EIL75_RS23260 ENOG4105C4R Atp-dependent dna helicase EIL75_RS23265 ENOG4106Z1T Nicotinamide Mononucleotide Transporter EIL75_RS23270 ENOG4107SXA Phosphorylase EIL75_RS23280 ENOG4105KQ5 peptidylprolyl cis-trans isomerase EIL75_RS23285 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase EIL75_RS23290 ENOG4105EMY transcriptional regulator EIL75_RS23305 ENOG4105C7B Threonine dehydratase EIL75_RS23315 ENOG4105CM2 brancheD-chain amino acid aminotransferase EIL75_RS23320 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit EIL75_RS23340 ENOG4105C0P Mg chelatase subunit ChlI EIL75_RS23385 ENOG4107EJG GntR family transcriptional regulator EIL75_RS23390 ENOG4105C0R drug resistance transporter emrb qaca subfamily EIL75_RS23395 ENOG4105ETE Transcriptional regulator (LacI family EIL75_RS23400 ENOG4108RVA ribokinase EIL75_RS23405 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EIL75_RS23410 ENOG4105CNN ABC, transporter EIL75_RS23445 ENOG4108VVK transcriptional Regulator, AsnC EIL75_RS23450 ENOG4105QTB Flavodoxin EIL75_RS23470 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation EIL75_RS23485 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) EIL75_RS23505 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) EIL75_RS23510 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) EIL75_RS23530 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) EIL75_RS23535 ENOG4105F9E Shikimate 5-dehydrogenase EIL75_RS23540 ENOG4105DM4 PTS System EIL75_RS23545 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) EIL75_RS23550 ENOG4105C8U phosphate abc transporter EIL75_RS23555 ENOG4105E2Z phosphate ABC transporter (Permease EIL75_RS23560 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) EIL75_RS23570 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 EIL75_RS23580 ENOG4105C7N Xanthine uracil vitamin C permease EIL75_RS23585 ENOG4108YYH Nadph-dependent fmn reductase EIL75_RS23590 ENOG4105E8Q phosphopantetheinyl transferase EIL75_RS23625 ENOG4105DFP Integrase EIL75_RS23655 ENOG4105VG0 50S ribosomal protein l34