locus-tag	class	description
A8181_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
A8181_RS00035	COG2271	Major facilitator Superfamily
A8181_RS00040	COG0561	phosphatase activity
A8181_RS00045	COG2186	Transcriptional regulator
A8181_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
A8181_RS00055	COG0800	Aldolase
A8181_RS00065	COG2271	Major facilitator Superfamily
A8181_RS00070	COG2198	Histidine kinase
A8181_RS00070	COG0784	Response regulator, receiver
A8181_RS00070	COG2205	protein histidine kinase activity
A8181_RS00075	COG1879	ABC-type sugar transport system periplasmic component
A8181_RS00080	COG0745	RESPONSE REGULATOR receiver
A8181_RS00085	COG3005	denitrification pathway
A8181_RS00100	COG1858	cytochrome C peroxidase
A8181_RS00110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8181_RS00115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8181_RS00120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8181_RS00130	COG1138	Cytochrome C-type biogenesis protein
A8181_RS00135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8181_RS00140	COG3088	subunit of a heme lyase
A8181_RS00140	COG4235	cytochrome complex assembly
A8181_RS00145	COG0823	Involved in the tonB-independent uptake of proteins
A8181_RS00150	COG5645	(Lipo)protein
A8181_RS00170	COG2149	membrane
A8181_RS00180	COG0641	radical SAM
A8181_RS00190	COG2610	gluconate transmembrane transporter activity
A8181_RS00195	COG0583	DNA-binding transcription factor activity
A8181_RS00205	COG2814	Major facilitator Superfamily
A8181_RS00230	COG0028	Belongs to the TPP enzyme family
A8181_RS00235	COG0440	acetolactate synthase activity
A8181_RS00240	COG1349	DNA-binding transcription factor activity
A8181_RS00250	COG0738	Major facilitator superfamily
A8181_RS00285	COG2188	Transcriptional regulator
A8181_RS00290	COG3711	transcriptional antiterminator
A8181_RS00290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS00295	COG3414	Phosphotransferase system galactitol-specific IIB component
A8181_RS00300	COG3775	system Galactitol-specific IIC component
A8181_RS00345	COG2723	6-phospho-beta-galactosidase activity
A8181_RS00365	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS00365	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8181_RS00375	COG3715	PTS system
A8181_RS00380	COG3716	PTS system mannose fructose sorbose family IID component
A8181_RS00395	COG5464	transposase or invertase
A8181_RS00425	COG1335	isochorismatase
A8181_RS00430	COG3710	Transcriptional regulator
A8181_RS00445	COG2771	luxR family
A8181_RS00450	COG2963	transposase activity
A8181_RS00460	COG2211	Major facilitator Superfamily
A8181_RS00465	COG1501	Belongs to the glycosyl hydrolase 31 family
A8181_RS00470	COG2982	Protein involved in outer membrane biogenesis
A8181_RS00475	COG2233	PERMEase
A8181_RS00480	COG0786	glutamate:sodium symporter activity
A8181_RS00490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A8181_RS00495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8181_RS00500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8181_RS00520	COG2860	membrane
A8181_RS00535	COG0583	DNA-binding transcription factor activity
A8181_RS00540	COG1561	YicC-like family, N-terminal region
A8181_RS00570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A8181_RS00600	COG1519	Transferase
A8181_RS00605	COG0859	PFAM glycosyl transferase family 9
A8181_RS00610	COG0438	transferase activity, transferring glycosyl groups
A8181_RS00690	COG1216	Glycosyl transferase, family 2
A8181_RS00695	COG2861	carbohydrate metabolic process
A8181_RS00700	COG4942	peptidase
A8181_RS00710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8181_RS00715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A8181_RS00735	COG2271	Major facilitator Superfamily
A8181_RS00750	COG1609	Transcriptional regulator
A8181_RS00755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A8181_RS00765	COG2186	Transcriptional regulator
A8181_RS00800	COG3722	fumarate hydratase activity
A8181_RS00815	COG2213	PTS system mannitol-specific
A8181_RS00815	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS00820	COG0625	glutathione transferase activity
A8181_RS00830	COG3276	selenocysteine insertion sequence binding
A8181_RS00835	COG1940	carbohydrate kinase activity
A8181_RS00840	COG1012	belongs to the aldehyde dehydrogenase family
A8181_RS00860	COG0235	Class ii aldolase
A8181_RS00865	COG3623	hexulose-6-phosphate isomerase
A8181_RS00870	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A8181_RS00875	COG1070	Carbohydrate kinase
A8181_RS00880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A8181_RS00885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A8181_RS00890	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A8181_RS00900	COG2731	YhcH YjgK YiaL family protein
A8181_RS00910	COG1414	Transcriptional regulator
A8181_RS00915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8181_RS00920	COG3977	Valine--pyruvate aminotransferase
A8181_RS00925	COG0366	Alpha amylase catalytic
A8181_RS00935	COG2992	FlgJ-related protein
A8181_RS00940	COG2207	Transcriptional regulator
A8181_RS00940	COG1609	Transcriptional regulator
A8181_RS00955	COG1070	Carbohydrate kinase
A8181_RS00960	COG4682	membrane
A8181_RS00965	COG3274	enterobacterial common antigen metabolic process
A8181_RS00995	COG1278	Cold shock
A8181_RS01000	COG2944	sequence-specific DNA binding
A8181_RS01015	COG2885	chlorophyll binding
A8181_RS01020	COG0243	molybdopterin cofactor binding
A8181_RS01025	COG0456	acetyltransferase
A8181_RS01030	COG2818	Glycosylase
A8181_RS01035	COG5571	outer membrane autotransporter
A8181_RS01085	COG1609	Transcriptional regulator
A8181_RS01100	COG0747	negative chemotaxis
A8181_RS01105	COG0601	transmembrane transport
A8181_RS01110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8181_RS01115	COG0444	Belongs to the ABC transporter superfamily
A8181_RS01120	COG4608	Belongs to the ABC transporter superfamily
A8181_RS01125	COG0814	amino acid
A8181_RS01130	COG2873	o-acetylhomoserine
A8181_RS01175	COG1215	transferase activity, transferring glycosyl groups
A8181_RS01195	COG2200	EAL domain
A8181_RS01195	COG2199	diguanylate cyclase activity
A8181_RS01210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8181_RS01215	COG2200	EAL domain
A8181_RS01220	COG2982	Protein involved in outer membrane biogenesis
A8181_RS01225	COG0477	Major facilitator Superfamily
A8181_RS01230	COG1295	ribonuclease BN
A8181_RS01235	COG0583	DNA-binding transcription factor activity
A8181_RS01240	COG2197	response regulator
A8181_RS01260	COG2188	Transcriptional regulator
A8181_RS01265	COG2222	sugar isomerase
A8181_RS01270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8181_RS01275	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8181_RS01285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8181_RS01290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A8181_RS01330	COG0306	phosphate transporter
A8181_RS01335	COG2081	HI0933 family
A8181_RS01340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8181_RS01345	COG1129	ABC transporter
A8181_RS01345	COG0842	Transport permease protein
A8181_RS01350	COG0842	Transport permease protein
A8181_RS01360	COG2091	lysine biosynthetic process via aminoadipic acid
A8181_RS01365	COG0628	permease
A8181_RS01380	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A8181_RS01400	COG3714	YhhN family
A8181_RS01410	COG3776	membrane
A8181_RS01415	COG0742	ribosomal rna small subunit methyltransferase
A8181_RS01420	COG0552	protein localization to endoplasmic reticulum
A8181_RS01425	COG2884	Cell division ATP-binding protein ftsE
A8181_RS01430	COG2177	Part of the ABC transporter FtsEX involved in
A8181_RS01505	COG0584	glycerophosphoryl diester phosphodiesterase
A8181_RS01515	COG0405	Gamma-glutamyltransferase
A8181_RS01520	COG1735	metal-dependent hydrolase with the TIM-barrel fold
A8181_RS01535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8181_RS01540	COG1247	-acetyltransferase
A8181_RS01545	COG0673	inositol 2-dehydrogenase activity
A8181_RS01550	COG1741	Belongs to the pirin family
A8181_RS01555	COG1609	Transcriptional regulator
A8181_RS01560	COG3265	gluconokinase activity
A8181_RS01565	COG2610	gluconate transmembrane transporter activity
A8181_RS01575	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A8181_RS01595	COG0058	SHG alpha-glucan phosphorylase activity
A8181_RS01600	COG1414	Transcriptional regulator
A8181_RS01605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A8181_RS01610	COG0129	dihydroxy-acid dehydratase activity
A8181_RS01620	COG0371	Dehydrogenase
A8181_RS01635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A8181_RS01650	COG1349	DNA-binding transcription factor activity
A8181_RS01660	COG0058	SHG alpha-glucan phosphorylase activity
A8181_RS01665	COG1640	4-alpha-glucanotransferase
A8181_RS01670	COG2610	gluconate transmembrane transporter activity
A8181_RS01690	COG5464	transposase or invertase
A8181_RS01705	COG1918	ferrous iron import across plasma membrane
A8181_RS01715	COG2183	response to ionizing radiation
A8181_RS01720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8181_RS01740	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A8181_RS01750	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A8181_RS01755	COG1011	Hydrolase
A8181_RS01765	COG0494	nUDIX hydrolase
A8181_RS01770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A8181_RS01775	COG4972	Pilus assembly protein
A8181_RS01780	COG3166	PFAM Fimbrial assembly family protein
A8181_RS01795	COG4796	Type ii and iii secretion system protein
A8181_RS01815	COG3266	domain, Protein
A8181_RS01820	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A8181_RS01825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A8181_RS01865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A8181_RS01900	COG1289	transmembrane transporter activity
A8181_RS01910	COG1765	OsmC-like protein
A8181_RS01915	COG3954	Phosphoribulokinase
A8181_RS01925	COG0429	hydrolase of the alpha beta-hydrolase fold
A8181_RS01940	COG0488	(ABC) transporter
A8181_RS01955	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A8181_RS01960	COG1047	Peptidyl-prolyl cis-trans
A8181_RS01970	COG0545	Peptidyl-prolyl cis-trans isomerase
A8181_RS01975	COG2964	Protein conserved in bacteria
A8181_RS02045	COG0051	transcription antitermination factor activity, RNA binding
A8181_RS02070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A8181_RS02150	COG0201	protein transport
A8181_RS02190	COG0789	Transcriptional regulator
A8181_RS02195	COG3036	rescue of stalled ribosome
A8181_RS02225	COG0758	DNA mediated transformation
A8181_RS02235	COG0551	DNA topoisomerase type I activity
A8181_RS02255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8181_RS02305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8181_RS02310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8181_RS02315	COG1309	transcriptional regulator
A8181_RS02330	COG2189	Belongs to the N(4) N(6)-methyltransferase family
A8181_RS02350	COG4145	pantothenate transmembrane transporter activity
A8181_RS02355	COG3924	membrane
A8181_RS02360	COG0439	Biotin carboxylase
A8181_RS02365	COG0511	ligase activity, forming carbon-carbon bonds
A8181_RS02380	COG0604	alcohol dehydrogenase
A8181_RS02385	COG2199	diguanylate cyclase activity
A8181_RS02385	COG2200	EAL domain
A8181_RS02400	COG1077	Cell shape determining protein MreB Mrl
A8181_RS02405	COG1792	Involved in formation and maintenance of cell shape
A8181_RS02410	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A8181_RS02425	COG3164	Protein of unknown function
A8181_RS02430	COG0312	modulator of DNA gyrase
A8181_RS02435	COG0583	DNA-binding transcription factor activity
A8181_RS02455	COG2732	(Barnase) inhibitor
A8181_RS02480	COG2188	Transcriptional regulator
A8181_RS02490	COG0471	metal ion transport
A8181_RS02495	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8181_RS02500	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8181_RS02505	COG3630	sodium ion export across plasma membrane
A8181_RS02510	COG5016	pyruvate
A8181_RS02510	COG0511	ligase activity, forming carbon-carbon bonds
A8181_RS02515	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A8181_RS02530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8181_RS02535	COG3105	Protein conserved in bacteria
A8181_RS02540	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A8181_RS02560	COG0625	glutathione transferase activity
A8181_RS02565	COG2969	positive regulation of protein catabolic process
A8181_RS02595	COG2731	YhcH YjgK YiaL family protein
A8181_RS02600	COG0402	S-adenosylhomocysteine deaminase activity
A8181_RS02605	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A8181_RS02615	COG0493	'glutamate synthase
A8181_RS02620	COG0067	glutamate synthase
A8181_RS02620	COG0069	glutamate synthase activity
A8181_RS02620	COG0070	glutamate synthase
A8181_RS02635	COG1242	4 iron, 4 sulfur cluster binding
A8181_RS02640	COG2198	Histidine kinase
A8181_RS02640	COG0784	Response regulator, receiver
A8181_RS02640	COG5002	protein histidine kinase activity
A8181_RS02645	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A8181_RS02655	COG0515	serine threonine protein kinase
A8181_RS02665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS02690	COG1137	ATPase activity
A8181_RS02695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A8181_RS02700	COG3117	lipopolysaccharide transmembrane transporter activity
A8181_RS02715	COG0530	calcium, potassium:sodium antiporter activity
A8181_RS02720	COG1127	ABC transporter
A8181_RS02725	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A8181_RS02730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A8181_RS02735	COG2854	intermembrane phospholipid transfer
A8181_RS02745	COG5007	Belongs to the BolA IbaG family
A8181_RS02755	COG3423	Transcriptional regulator
A8181_RS02760	COG0142	geranyltranstransferase activity
A8181_RS02775	COG0697	spore germination
A8181_RS02785	COG2027	D-alanyl-D-alanine carboxypeptidase
A8181_RS02795	COG1534	Rna-binding protein
A8181_RS02825	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A8181_RS02890	COG0513	Belongs to the DEAD box helicase family
A8181_RS02895	COG0814	amino acid
A8181_RS02900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8181_RS02905	COG0826	peptidase U32
A8181_RS02910	COG0826	peptidase U32
A8181_RS02915	COG3154	lipid carrier protein
A8181_RS02920	COG3153	acetyltransferase
A8181_RS02935	COG0693	protein deglycase activity
A8181_RS02940	COG0702	epimerase
A8181_RS02945	COG2823	Periplasmic or secreted lipoprotein
A8181_RS02960	COG3107	peptidoglycan biosynthetic process
A8181_RS02965	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A8181_RS02975	COG1063	alcohol dehydrogenase
A8181_RS02980	COG3775	system Galactitol-specific IIC component
A8181_RS02985	COG3414	Phosphotransferase system galactitol-specific IIB component
A8181_RS02990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS03005	COG2721	sulfolactate sulfo-lyase activity
A8181_RS03015	COG2084	Dehydrogenase
A8181_RS03020	COG1929	Belongs to the glycerate kinase type-1 family
A8181_RS03035	COG0583	DNA-binding transcription factor activity
A8181_RS03055	COG1882	Formate acetyltransferase
A8181_RS03060	COG1760	l-serine dehydratase
A8181_RS03065	COG0814	amino acid
A8181_RS03080	COG1741	Belongs to the pirin family
A8181_RS03085	COG0583	DNA-binding transcription factor activity
A8181_RS03090	COG3152	Membrane
A8181_RS03095	COG0435	Glutathione S-transferase
A8181_RS03100	COG2259	Doxx family
A8181_RS03110	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
A8181_RS03115	COG4575	ribosome binding
A8181_RS03120	COG1422	Protein of unknown function (DUF1090)
A8181_RS03130	COG0586	Pfam SNARE associated Golgi protein
A8181_RS03145	COG0673	inositol 2-dehydrogenase activity
A8181_RS03150	COG2949	membrane
A8181_RS03155	COG1451	nucleotide metabolic process
A8181_RS03165	COG1902	pentaerythritol trinitrate reductase activity
A8181_RS03165	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8181_RS03180	COG0840	transmembrane signaling receptor activity
A8181_RS03185	COG0840	transmembrane signaling receptor activity
A8181_RS03190	COG1695	Transcriptional regulator
A8181_RS03195	COG2375	cellular response to nickel ion
A8181_RS03220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A8181_RS03235	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8181_RS03245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A8181_RS03260	COG4991	sh3 domain protein
A8181_RS03265	COG3025	triphosphatase activity
A8181_RS03285	COG2268	Band 7 protein
A8181_RS03290	COG1585	Membrane protein implicated in regulation of membrane protease activity
A8181_RS03335	COG3384	dioxygenase
A8181_RS03340	COG0754	glutathionylspermidine amidase activity
A8181_RS03360	COG0494	nUDIX hydrolase
A8181_RS03365	COG3151	Protein conserved in bacteria
A8181_RS03370	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A8181_RS03375	COG3150	esterase
A8181_RS03385	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A8181_RS03390	COG2249	NAD(P)H dehydrogenase (quinone) activity
A8181_RS03405	COG3111	PFAM Bacterial OB fold (BOF) protein
A8181_RS03410	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A8181_RS03460	COG0471	metal ion transport
A8181_RS03470	COG1979	alcohol dehydrogenase
A8181_RS03475	COG2207	Transcriptional regulator
A8181_RS03495	COG0848	biopolymer transport protein
A8181_RS03500	COG1028	Short-chain dehydrogenase reductase Sdr
A8181_RS03530	COG0840	transmembrane signaling receptor activity
A8181_RS03545	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A8181_RS03550	COG0437	4 iron, 4 sulfur cluster binding
A8181_RS03555	COG5557	Pfam Polysulphide reductase, NrfD
A8181_RS03560	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A8181_RS03565	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A8181_RS03570	COG1773	rubredoxin
A8181_RS03580	COG0298	carbon dioxide binding
A8181_RS03585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8181_RS03595	COG0625	glutathione transferase activity
A8181_RS03600	COG0754	glutathionylspermidine amidase activity
A8181_RS03620	COG0246	Mannitol dehydrogenase
A8181_RS03630	COG2271	Major facilitator Superfamily
A8181_RS03660	COG1012	belongs to the aldehyde dehydrogenase family
A8181_RS03665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8181_RS03675	COG0531	amino acid
A8181_RS03705	COG2301	Belongs to the HpcH HpaI aldolase family
A8181_RS03710	COG2030	dehydratase
A8181_RS03715	COG0427	acetyl-CoA hydrolase
A8181_RS03730	COG1811	Na channel or pump
A8181_RS03740	COG1982	Orn Lys Arg decarboxylase major
A8181_RS03745	COG2211	Major facilitator Superfamily
A8181_RS03775	COG3171	Protein conserved in bacteria
A8181_RS03785	COG0252	asparaginase activity
A8181_RS03795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A8181_RS03810	COG0762	integral membrane protein
A8181_RS03815	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A8181_RS03820	COG2805	Type II/IV secretion system protein
A8181_RS03845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A8181_RS03850	COG2356	endonuclease I
A8181_RS03860	COG2814	Major facilitator Superfamily
A8181_RS03880	COG1166	arginine decarboxylase activity
A8181_RS03890	COG2186	Transcriptional regulator
A8181_RS03895	COG4948	Mandelate Racemase Muconate Lactonizing
A8181_RS03900	COG4948	Mandelate Racemase Muconate Lactonizing
A8181_RS03905	COG0246	Mannitol dehydrogenase
A8181_RS03910	COG1063	alcohol dehydrogenase
A8181_RS03915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A8181_RS03920	COG2731	YhcH YjgK YiaL family protein
A8181_RS03925	COG2267	carboxylic ester hydrolase activity
A8181_RS03935	COG0501	Belongs to the peptidase M48B family
A8181_RS03940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A8181_RS03945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS03950	COG2213	PTS system mannitol-specific
A8181_RS03955	COG1063	alcohol dehydrogenase
A8181_RS03960	COG1494	fructose-1,6-bisphosphatase
A8181_RS03970	COG1072	(Pantothenic acid kinase))
A8181_RS03975	COG1122	ATPase activity
A8181_RS03980	COG1122	ATPase activity
A8181_RS04015	COG0191	fructose-bisphosphate aldolase activity
A8181_RS04020	COG0668	transmembrane transport
A8181_RS04030	COG2968	Membrane
A8181_RS04050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8181_RS04055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A8181_RS04080	COG0006	proline dipeptidase activity
A8181_RS04085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8181_RS04090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8181_RS04125	COG2723	6-phospho-beta-galactosidase activity
A8181_RS04135	COG1272	protein, Hemolysin III
A8181_RS04205	COG4942	peptidase
A8181_RS04260	COG3188	usher protein
A8181_RS04295	COG0814	amino acid
A8181_RS04310	COG0183	Belongs to the thiolase family
A8181_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
A8181_RS04330	COG2814	Major facilitator Superfamily
A8181_RS04335	COG1794	racemase activity, acting on amino acids and derivatives
A8181_RS04340	COG0583	DNA-binding transcription factor activity
A8181_RS04350	COG1609	Transcriptional regulator
A8181_RS04370	COG0667	Aldo Keto reductase
A8181_RS04380	COG0861	Integral membrane protein TerC family
A8181_RS04415	COG2165	general secretion pathway protein
A8181_RS04420	COG4795	General secretion pathway protein
A8181_RS04430	COG4967	type IV pilus modification protein PilV
A8181_RS04435	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A8181_RS04445	COG1074	ATP-dependent DNA helicase activity
A8181_RS04450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A8181_RS04460	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8181_RS04475	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A8181_RS04480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A8181_RS04485	COG2962	Rard protein
A8181_RS04490	COG2166	iron-sulfur cluster assembly
A8181_RS04495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A8181_RS04505	COG0583	DNA-binding transcription factor activity
A8181_RS04510	COG2363	Small membrane protein
A8181_RS04520	COG1349	DNA-binding transcription factor activity
A8181_RS04540	COG0738	Major facilitator superfamily
A8181_RS04545	COG0235	Class ii aldolase
A8181_RS04550	COG1454	alcohol dehydrogenase
A8181_RS04565	COG1760	l-serine dehydratase
A8181_RS04570	COG0814	amino acid
A8181_RS04575	COG1611	Belongs to the LOG family
A8181_RS04595	COG3098	single-species biofilm formation
A8181_RS04605	COG0716	FMN binding
A8181_RS04615	COG2271	Major facilitator Superfamily
A8181_RS04620	COG4948	Mandelate Racemase Muconate Lactonizing
A8181_RS04625	COG4948	Mandelate Racemase Muconate Lactonizing
A8181_RS04630	COG1929	Belongs to the glycerate kinase type-1 family
A8181_RS04635	COG2205	protein histidine kinase activity
A8181_RS04635	COG3437	response regulator, receiver
A8181_RS04635	COG3850	Histidine kinase
A8181_RS04635	COG4999	Histidine kinase
A8181_RS04645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8181_RS04670	COG3539	Fimbrial protein
A8181_RS04675	COG3121	Chaperone
A8181_RS04680	COG3188	usher protein
A8181_RS04685	COG3539	Fimbrial protein
A8181_RS04690	COG3956	TIGRFAM MazG family protein
A8181_RS04705	COG0602	queuosine metabolic process
A8181_RS04710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A8181_RS04710	COG0321	lipoyl(octanoyl) transferase activity
A8181_RS04715	COG0720	synthase
A8181_RS04770	COG1857	crispr-associated protein
A8181_RS04785	COG1518	maintenance of DNA repeat elements
A8181_RS04790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8181_RS04795	COG2234	aminopeptidase activity
A8181_RS04865	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8181_RS04870	COG0163	prenyltransferase activity
A8181_RS04880	COG1349	DNA-binding transcription factor activity
A8181_RS04885	COG2084	Dehydrogenase
A8181_RS04895	COG0235	Class ii aldolase
A8181_RS04900	COG3622	Belongs to the hyi family
A8181_RS04905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8181_RS04910	COG2610	gluconate transmembrane transporter activity
A8181_RS04920	COG0477	Major facilitator Superfamily
A8181_RS05005	COG2207	Transcriptional regulator
A8181_RS05095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A8181_RS05185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8181_RS05190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8181_RS05195	COG1121	(ABC) transporter
A8181_RS05215	COG0309	Hydrogenase expression formation protein (HypE)
A8181_RS05225	COG0298	carbon dioxide binding
A8181_RS05230	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A8181_RS05250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8181_RS05255	COG0651	ATP synthesis coupled electron transport
A8181_RS05260	COG0650	Formate hydrogenlyase subunit 4
A8181_RS05265	COG3261	NADH dehydrogenase
A8181_RS05265	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A8181_RS05270	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8181_RS05275	COG3260	NADH ubiquinone oxidoreductase 20
A8181_RS05285	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A8181_RS05295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8181_RS05300	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A8181_RS05325	COG1349	DNA-binding transcription factor activity
A8181_RS05330	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
A8181_RS05345	COG3732	PTS system glucitol sorbitol-specific
A8181_RS05350	COG3730	PTS system glucitol sorbitol-specific
A8181_RS05355	COG2951	lytic endotransglycosylase activity
A8181_RS05365	COG1546	Belongs to the CinA family
A8181_RS05390	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A8181_RS05425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8181_RS05430	COG1238	metal cluster binding
A8181_RS05455	COG1566	PFAM secretion protein HlyD family protein
A8181_RS05460	COG1846	Transcriptional regulator
A8181_RS05465	COG2814	Major facilitator Superfamily
A8181_RS05510	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8181_RS05520	COG4575	ribosome binding
A8181_RS05550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8181_RS05555	COG0640	Transcriptional regulator
A8181_RS05560	COG0401	homolog of Blt101
A8181_RS05565	COG1652	LysM domain
A8181_RS05570	COG1802	Transcriptional regulator
A8181_RS05575	COG1113	amino acid transport
A8181_RS05580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8181_RS05585	COG1012	belongs to the aldehyde dehydrogenase family
A8181_RS05590	COG0579	oxidoreductase
A8181_RS05625	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A8181_RS05640	COG2990	Protein conserved in bacteria
A8181_RS05665	COG2819	hydrolase of the alpha beta superfamily
A8181_RS05765	COG0582	viral genome integration into host DNA
A8181_RS05770	COG4974	Belongs to the 'phage' integrase family
A8181_RS05835	COG4695	Portal protein
A8181_RS05930	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8181_RS05980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8181_RS06005	COG2867	negative regulation of translational initiation
A8181_RS06020	COG0497	DNA recombination
A8181_RS06045	COG4536	flavin adenine dinucleotide binding
A8181_RS06050	COG4137	Cytochrome C assembly protein
A8181_RS06060	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A8181_RS06085	COG2199	diguanylate cyclase activity
A8181_RS06100	COG0287	Prephenate dehydrogenase
A8181_RS06100	COG1605	Chorismate mutase
A8181_RS06110	COG0077	Prephenate dehydratase
A8181_RS06110	COG1605	Chorismate mutase
A8181_RS06115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A8181_RS06120	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8181_RS06135	COG0542	response to heat
A8181_RS06170	COG0477	Major facilitator Superfamily
A8181_RS06175	COG5544	Lipoprotein
A8181_RS06180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8181_RS06190	COG3148	PFAM DTW domain containing protein
A8181_RS06195	COG3118	belongs to the thioredoxin family
A8181_RS06200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8181_RS06220	COG0583	DNA-binding transcription factor activity
A8181_RS06225	COG0513	Belongs to the DEAD box helicase family
A8181_RS06235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A8181_RS06260	COG3086	response to oxidative stress
A8181_RS06290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8181_RS06315	COG1192	Involved in chromosome partitioning
A8181_RS06425	COG4220	transposase activity
A8181_RS06535	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8181_RS06555	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A8181_RS06625	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8181_RS06630	COG0583	DNA-binding transcription factor activity
A8181_RS06635	COG2223	nitrite transmembrane transporter activity
A8181_RS06640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A8181_RS06645	COG1737	Transcriptional regulator
A8181_RS06655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8181_RS06655	COG1263	PTS System
A8181_RS06660	COG0560	Phosphoserine phosphatase
A8181_RS06685	COG2205	protein histidine kinase activity
A8181_RS06690	COG3170	Tfp pilus assembly protein FimV
A8181_RS06695	COG2204	response regulator
A8181_RS06700	COG0347	Belongs to the P(II) protein family
A8181_RS06705	COG3104	oligopeptide transport
A8181_RS06715	COG0531	amino acid
A8181_RS06720	COG3710	Transcriptional regulator
A8181_RS06725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8181_RS06725	COG1017	nitric oxide dioxygenase activity
A8181_RS06735	COG2814	Major facilitator Superfamily
A8181_RS06740	COG3711	transcriptional antiterminator
A8181_RS06750	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A8181_RS06795	COG0822	iron-sulfur transferase activity
A8181_RS06815	COG0633	Ferredoxin
A8181_RS06820	COG2975	iron-sulfur cluster assembly
A8181_RS06855	COG2897	thiosulfate sulfurtransferase activity
A8181_RS06860	COG2373	Large extracellular alpha-helical protein
A8181_RS06865	COG4953	penicillin-binding protein 1C
A8181_RS06870	COG0243	molybdopterin cofactor binding
A8181_RS06875	COG0437	4 iron, 4 sulfur cluster binding
A8181_RS06920	COG2976	Protein conserved in bacteria
A8181_RS06935	COG1645	bacterial-type flagellum-dependent swarming motility
A8181_RS06975	COG0516	GMP reductase activity
A8181_RS06975	COG0517	IMP dehydrogenase activity
A8181_RS07010	COG2200	EAL domain
A8181_RS07025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A8181_RS07045	COG2233	PERMEase
A8181_RS07055	COG1393	Belongs to the ArsC family
A8181_RS07065	COG0628	permease
A8181_RS07070	COG3835	regulator
A8181_RS07075	COG2610	gluconate transmembrane transporter activity
A8181_RS07080	COG1929	Belongs to the glycerate kinase type-1 family
A8181_RS07085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A8181_RS07090	COG2716	regulation of RNA biosynthetic process
A8181_RS07100	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A8181_RS07115	COG2321	neutral zinc metallopeptidase
A8181_RS07135	COG1393	Belongs to the ArsC family
A8181_RS07140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8181_RS07145	COG3850	Histidine kinase
A8181_RS07150	COG0493	'glutamate synthase
A8181_RS07150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8181_RS07170	COG5342	invasion associated locus B
A8181_RS07180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A8181_RS07320	COG2837	iron assimilation
A8181_RS07340	COG4208	sulfate ABC transporter
A8181_RS07400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS07430	COG3530	Putative quorum-sensing-regulated virulence factor
A8181_RS07435	COG0385	Bile acid
A8181_RS07440	COG0583	DNA-binding transcription factor activity
A8181_RS07450	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A8181_RS07455	COG2211	Major facilitator Superfamily
A8181_RS07465	COG0583	DNA-binding transcription factor activity
A8181_RS07495	COG3415	Transposase
A8181_RS07500	COG3415	Transposase
A8181_RS07520	COG2199	diguanylate cyclase activity
A8181_RS07520	COG2200	EAL domain
A8181_RS07525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8181_RS07540	COG0667	Aldo Keto reductase
A8181_RS07545	COG3961	Belongs to the TPP enzyme family
A8181_RS07565	COG0436	Aminotransferase
A8181_RS07570	COG1560	Kdo2-lipid A biosynthetic process
A8181_RS07615	COG2116	formate transmembrane transporter activity
A8181_RS07630	COG3691	Protein conserved in bacteria
A8181_RS07645	COG2062	phosphohistidine phosphatase, SixA
A8181_RS07670	COG0730	response to heat
A8181_RS07675	COG3101	peptidyl-lysine hydroxylation
A8181_RS07690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8181_RS07710	COG3423	Transcriptional regulator
A8181_RS07735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8181_RS07745	COG0586	Pfam SNARE associated Golgi protein
A8181_RS07755	COG0285	dihydrofolate synthase activity
A8181_RS07760	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A8181_RS07765	COG1286	toxin biosynthetic process
A8181_RS07770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A8181_RS07775	COG3829	transcription factor binding
A8181_RS07785	COG0531	amino acid
A8181_RS07790	COG3457	Alanine racemase
A8181_RS07795	COG0833	amino acid
A8181_RS07835	COG1090	epimerase
A8181_RS07840	COG0625	glutathione transferase activity
A8181_RS07845	COG0625	glutathione transferase activity
A8181_RS07850	COG0622	Phosphoesterase
A8181_RS07860	COG1609	Transcriptional regulator
A8181_RS07870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS07880	COG3037	sugar-specific permease SgaT UlaA
A8181_RS07885	COG3959	Transketolase, thiamine diphosphate binding domain
A8181_RS07890	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A8181_RS07895	COG1288	antiporter activity
A8181_RS07920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8181_RS07925	COG0490	domain, Protein
A8181_RS07925	COG0471	metal ion transport
A8181_RS07935	COG0436	Aminotransferase
A8181_RS07945	COG0583	DNA-binding transcription factor activity
A8181_RS07990	COG0839	Belongs to the complex I subunit 6 family
A8181_RS08000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A8181_RS08005	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8181_RS08015	COG0784	Response regulator, receiver
A8181_RS08015	COG0835	chemotaxis
A8181_RS08025	COG2153	protein acetylation
A8181_RS08030	COG4575	ribosome binding
A8181_RS08035	COG1169	isochorismate synthase
A8181_RS08125	COG1414	Transcriptional regulator
A8181_RS08135	COG2271	Major facilitator Superfamily
A8181_RS08160	COG0247	lactate metabolic process
A8181_RS08170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A8181_RS08175	COG2271	Major facilitator Superfamily
A8181_RS08180	COG0584	glycerophosphoryl diester phosphodiesterase
A8181_RS08185	COG0583	DNA-binding transcription factor activity
A8181_RS08190	COG2814	Major facilitator Superfamily
A8181_RS08195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8181_RS08225	COG4948	Mandelate Racemase Muconate Lactonizing
A8181_RS08250	COG0642	Histidine kinase
A8181_RS08250	COG2198	Histidine kinase
A8181_RS08280	COG4615	Cyclic peptide transporter
A8181_RS08290	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8181_RS08290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8181_RS08295	COG3062	negative regulation of establishment of protein localization
A8181_RS08305	COG0437	4 iron, 4 sulfur cluster binding
A8181_RS08310	COG0348	domain, Protein
A8181_RS08315	COG3043	anaerobic respiration
A8181_RS08320	COG3005	denitrification pathway
A8181_RS08330	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8181_RS08335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8181_RS08340	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8181_RS08350	COG1138	Cytochrome C-type biogenesis protein
A8181_RS08355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8181_RS08360	COG4235	cytochrome complex assembly
A8181_RS08360	COG3088	subunit of a heme lyase
A8181_RS08365	COG2197	response regulator
A8181_RS08385	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8181_RS08440	COG1061	Type III restriction enzyme res subunit
A8181_RS08450	COG2814	Major facilitator Superfamily
A8181_RS08465	COG4172	Belongs to the ABC transporter superfamily
A8181_RS08470	COG4239	(ABC) transporter, permease
A8181_RS08475	COG4174	ABC transporter (Permease)
A8181_RS08480	COG4166	transmembrane transport
A8181_RS08485	COG2200	EAL domain
A8181_RS08490	COG0791	NLP P60 protein
A8181_RS08500	COG0671	phosphoesterase, PA-phosphatase related
A8181_RS08505	COG0523	cobalamin synthesis protein
A8181_RS08540	COG1105	Belongs to the carbohydrate kinase PfkB family
A8181_RS08545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8181_RS08545	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A8181_RS08545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8181_RS08555	COG2855	membrane
A8181_RS08560	COG0583	DNA-binding transcription factor activity
A8181_RS08565	COG0833	amino acid
A8181_RS08575	COG4771	TonB-dependent receptor
A8181_RS08580	COG2271	Major facilitator Superfamily
A8181_RS08585	COG0560	Phosphoserine phosphatase
A8181_RS08590	COG1760	l-serine dehydratase
A8181_RS08615	COG2311	Membrane
A8181_RS08645	COG0493	'glutamate synthase
A8181_RS08655	COG2949	membrane
A8181_RS08665	COG1346	cytolysis
A8181_RS08680	COG2271	Major facilitator Superfamily
A8181_RS08695	COG0625	glutathione transferase activity
A8181_RS08700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8181_RS08715	COG1538	Outer membrane efflux protein
A8181_RS08720	COG1028	Short-chain dehydrogenase reductase Sdr
A8181_RS08725	COG0586	Pfam SNARE associated Golgi protein
A8181_RS08740	COG1686	Belongs to the peptidase S11 family
A8181_RS08745	COG0277	FAD linked oxidase domain protein
A8181_RS08755	COG1732	Glycine betaine
A8181_RS08760	COG1174	glycine betaine transport
A8181_RS08765	COG1125	glycine betaine transport
A8181_RS08770	COG1174	glycine betaine transport
A8181_RS08785	COG3275	phosphorelay sensor kinase activity
A8181_RS08795	COG4807	Protein conserved in bacteria
A8181_RS08805	COG4808	Protein conserved in bacteria
A8181_RS08830	COG3121	Chaperone
A8181_RS08835	COG3188	usher protein
A8181_RS08840	COG3539	Fimbrial protein
A8181_RS08845	COG5455	response to cobalt ion
A8181_RS08860	COG2188	Transcriptional regulator
A8181_RS08865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8181_RS08870	COG1397	ADP-ribosylglycohydrolase
A8181_RS08875	COG2211	Major facilitator Superfamily
A8181_RS08880	COG1830	Aldolase
A8181_RS08905	COG0826	peptidase U32
A8181_RS08930	COG0745	RESPONSE REGULATOR receiver
A8181_RS08935	COG2205	protein histidine kinase activity
A8181_RS08960	COG0443	Heat shock 70 kDa protein
A8181_RS08970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A8181_RS08975	COG3447	MASE1 domain protein
A8181_RS08975	COG5002	protein histidine kinase activity
A8181_RS08975	COG5001	Diguanylate cyclase
A8181_RS08990	COG2982	Protein involved in outer membrane biogenesis
A8181_RS08995	COG1253	flavin adenine dinucleotide binding
A8181_RS09020	COG0463	Glycosyl transferase, family 2
A8181_RS09025	COG1045	serine acetyltransferase
A8181_RS09030	COG0438	transferase activity, transferring glycosyl groups
A8181_RS09040	COG1216	Glycosyl transferase, family 2
A8181_RS09045	COG0110	maltose O-acetyltransferase activity
A8181_RS09050	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
A8181_RS09055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8181_RS09065	COG0297	glycogen (starch) synthase activity
A8181_RS09080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A8181_RS09085	COG2244	polysaccharide biosynthetic process
A8181_RS09090	COG2327	Polysaccharide pyruvyl transferase
A8181_RS09135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A8181_RS09160	COG0463	Glycosyl transferase, family 2
A8181_RS09185	COG0438	transferase activity, transferring glycosyl groups
A8181_RS09270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8181_RS09275	COG0583	DNA-binding transcription factor activity
A8181_RS09280	COG0531	amino acid
A8181_RS09285	COG2925	Exonuclease
A8181_RS09330	COG1289	transmembrane transporter activity
A8181_RS09365	COG4656	Part of a membrane complex involved in electron transport
A8181_RS09370	COG1454	alcohol dehydrogenase
A8181_RS09370	COG1012	belongs to the aldehyde dehydrogenase family
A8181_RS09385	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
A8181_RS09400	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A8181_RS09530	COG1122	ATPase activity
A8181_RS09565	COG0640	Transcriptional regulator
A8181_RS09570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A8181_RS09585	COG0798	PFAM Bile acid sodium symporter
A8181_RS09605	COG0534	Mate efflux family protein
A8181_RS09620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A8181_RS09630	COG1666	GTP binding
A8181_RS09670	COG0582	viral genome integration into host DNA
A8181_RS09715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A8181_RS09730	COG1418	mRNA catabolic process
A8181_RS09735	COG0270	DNA (cytosine-5-)-methyltransferase activity
A8181_RS09740	COG3727	T/G mismatch-specific endonuclease activity
A8181_RS09745	COG0697	spore germination
A8181_RS09750	COG2354	Protein conserved in bacteria
A8181_RS09755	COG5475	Uncharacterized small protein (DUF2158)
A8181_RS09865	COG0425	Belongs to the sulfur carrier protein TusA family
A8181_RS09925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8181_RS09935	COG0765	amino acid transport
A8181_RS09940	COG1126	abc transporter atp-binding protein
A8181_RS09945	COG2197	response regulator
A8181_RS09955	COG2197	response regulator
A8181_RS10005	COG0814	amino acid
A8181_RS10015	COG1528	Iron-storage protein
A8181_RS10030	COG1528	Iron-storage protein
A8181_RS10040	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8181_RS10130	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A8181_RS10145	COG3102	Protein conserved in bacteria
A8181_RS10165	COG3788	relative of glutathione S-transferase, MAPEG superfamily
A8181_RS10170	COG1801	Protein of unknown function DUF72
A8181_RS10175	COG1335	isochorismatase
A8181_RS10185	COG0494	nUDIX hydrolase
A8181_RS10220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8181_RS10230	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A8181_RS10235	COG0739	heme binding
A8181_RS10245	COG1560	Kdo2-lipid A biosynthetic process
A8181_RS10255	COG1737	Transcriptional regulator
A8181_RS10265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A8181_RS10270	COG0129	dihydroxy-acid dehydratase activity
A8181_RS10275	COG0800	Aldolase
A8181_RS10285	COG3141	response to X-ray
A8181_RS10295	COG2979	Protein of unknown function (DUF533)
A8181_RS10300	COG1770	oligopeptidase
A8181_RS10305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8181_RS10310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8181_RS10320	COG2372	response to copper ion
A8181_RS10325	COG1276	copper resistance
A8181_RS10335	COG0582	viral genome integration into host DNA
A8181_RS10340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8181_RS10395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A8181_RS10480	COG5562	phage envelope protein
A8181_RS10510	COG3008	intermembrane lipid transfer
A8181_RS10515	COG2995	paraquat-inducible protein a
A8181_RS10520	COG1956	GAF domain-containing protein
A8181_RS10540	COG2814	Major facilitator Superfamily
A8181_RS10545	COG1414	Transcriptional regulator
A8181_RS10575	COG0768	penicillin binding
A8181_RS10580	COG2226	methyltransferase
A8181_RS10600	COG3716	PTS system mannose fructose sorbose family IID component
A8181_RS10605	COG3715	PTS system
A8181_RS10610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS10610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8181_RS10620	COG1253	flavin adenine dinucleotide binding
A8181_RS10625	COG2200	EAL domain
A8181_RS10630	COG1760	l-serine dehydratase
A8181_RS10650	COG0251	oxidation-reduction process
A8181_RS10655	COG1199	ATP-dependent helicase activity
A8181_RS10665	COG3065	identical protein binding
A8181_RS10680	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A8181_RS10690	COG2894	cell division
A8181_RS10705	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8181_RS10740	COG2719	SpoVR family
A8181_RS10760	COG1619	proteins homologs of microcin C7 resistance protein MccF
A8181_RS10785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A8181_RS10795	COG1294	oxidase, subunit
A8181_RS10800	COG1271	oxidase subunit
A8181_RS10805	COG1773	rubredoxin
A8181_RS10810	COG1999	signal sequence binding
A8181_RS10815	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A8181_RS10820	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
A8181_RS10830	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A8181_RS10850	COG0012	GTP binding
A8181_RS10865	COG0659	secondary active sulfate transmembrane transporter activity
A8181_RS10915	COG0387	Pfam Sodium calcium exchanger
A8181_RS10920	COG4572	Cation transport regulator
A8181_RS10925	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A8181_RS10930	COG4932	domain protein
A8181_RS10935	COG2197	response regulator
A8181_RS10940	COG3850	Histidine kinase
A8181_RS10950	COG2223	nitrite transmembrane transporter activity
A8181_RS10955	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A8181_RS10960	COG1140	nitrate reductase beta subunit
A8181_RS10965	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A8181_RS10970	COG2181	nitrate reductase activity
A8181_RS11015	COG0788	formyltetrahydrofolate deformylase activity
A8181_RS11025	COG1752	Esterase of the alpha-beta hydrolase superfamily
A8181_RS11030	COG0745	RESPONSE REGULATOR receiver
A8181_RS11035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A8181_RS11050	COG1012	belongs to the aldehyde dehydrogenase family
A8181_RS11050	COG1454	alcohol dehydrogenase
A8181_RS11055	COG2095	MarC family integral membrane protein
A8181_RS11090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8181_RS11105	COG2350	Protein conserved in bacteria
A8181_RS11130	COG0727	PFAM Uncharacterised protein family (UPF0153)
A8181_RS11140	COG3546	catalase activity
A8181_RS11145	COG3685	Protein conserved in bacteria
A8181_RS11150	COG3685	Protein conserved in bacteria
A8181_RS11155	COG3729	General stress protein
A8181_RS11195	COG0009	L-threonylcarbamoyladenylate synthase
A8181_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
A8181_RS11215	COG0616	signal peptide processing
A8181_RS11260	COG0671	phosphoesterase, PA-phosphatase related
A8181_RS11270	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A8181_RS11275	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A8181_RS11295	COG1349	DNA-binding transcription factor activity
A8181_RS11305	COG5001	Diguanylate cyclase
A8181_RS11320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8181_RS11320	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8181_RS11375	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A8181_RS11380	COG1842	Phage shock protein A
A8181_RS11390	COG1983	PspC domain protein
A8181_RS11400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8181_RS11405	COG3106	COG3106 Predicted ATPase
A8181_RS11425	COG4948	Mandelate Racemase Muconate Lactonizing
A8181_RS11430	COG2866	Carboxypeptidase
A8181_RS11435	COG4166	transmembrane transport
A8181_RS11445	COG0583	DNA-binding transcription factor activity
A8181_RS11450	COG0656	L-ascorbic acid biosynthetic process
A8181_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
A8181_RS11460	COG1309	transcriptional regulator
A8181_RS11495	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A8181_RS11515	COG0668	transmembrane transport
A8181_RS11520	COG3182	Iron-regulated membrane protein
A8181_RS11540	COG2840	Smr protein MutS2
A8181_RS11550	COG0840	transmembrane signaling receptor activity
A8181_RS11565	COG0513	Belongs to the DEAD box helicase family
A8181_RS11580	COG2076	Multidrug Resistance protein
A8181_RS11595	COG1013	pyruvate-flavodoxin oxidoreductase activity
A8181_RS11595	COG0674	pyruvate-flavodoxin oxidoreductase activity
A8181_RS11595	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A8181_RS11595	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8181_RS11600	COG3042	response to heat
A8181_RS11605	COG3187	Heat shock protein
A8181_RS11610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8181_RS11615	COG2911	Protein conserved in bacteria
A8181_RS11625	COG3784	Protein of unknown function (DUF1318)
A8181_RS11640	COG1643	Atp-dependent helicase
A8181_RS11645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A8181_RS11650	COG3038	cytochrome b561
A8181_RS11655	COG0500	methyltransferase
A8181_RS11665	COG0765	amino acid transport
A8181_RS11680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8181_RS11715	COG0840	transmembrane signaling receptor activity
A8181_RS11720	COG0583	DNA-binding transcription factor activity
A8181_RS11725	COG5383	Protein conserved in bacteria
A8181_RS11730	COG2272	Belongs to the type-B carboxylesterase lipase family
A8181_RS11735	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
A8181_RS11740	COG2353	YceI-like domain
A8181_RS11745	COG1304	FMN binding
A8181_RS11755	COG1349	DNA-binding transcription factor activity
A8181_RS11760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A8181_RS11765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS11770	COG0434	BtpA family
A8181_RS11775	COG3775	system Galactitol-specific IIC component
A8181_RS11780	COG3414	Phosphotransferase system galactitol-specific IIB component
A8181_RS11790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8181_RS11795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8181_RS11800	COG1275	C4-dicarboxylate transporter malic acid transport protein
A8181_RS11805	COG0500	methyltransferase
A8181_RS11820	COG1396	sequence-specific DNA binding
A8181_RS11825	COG0826	peptidase U32
A8181_RS11850	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
A8181_RS11855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8181_RS11895	COG3238	Protein conserved in bacteria
A8181_RS11905	COG2130	NADP-dependent
A8181_RS11910	COG1802	Transcriptional regulator
A8181_RS11915	COG4772	TonB-dependent receptor
A8181_RS11955	COG2181	nitrate reductase activity
A8181_RS11960	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A8181_RS11965	COG1140	nitrate reductase beta subunit
A8181_RS11970	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A8181_RS12010	COG3383	formate dehydrogenase (NAD+) activity
A8181_RS12010	COG0243	molybdopterin cofactor binding
A8181_RS12015	COG3383	formate dehydrogenase (NAD+) activity
A8181_RS12015	COG0243	molybdopterin cofactor binding
A8181_RS12020	COG0437	4 iron, 4 sulfur cluster binding
A8181_RS12025	COG2864	formate dehydrogenase
A8181_RS12030	COG1064	alcohol dehydrogenase
A8181_RS12050	COG1764	response to oxidative stress
A8181_RS12065	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A8181_RS12080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A8181_RS12085	COG1757	Na H antiporter
A8181_RS12090	COG1609	Transcriptional regulator
A8181_RS12135	COG0251	oxidation-reduction process
A8181_RS12140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A8181_RS12165	COG2271	Major facilitator Superfamily
A8181_RS12170	COG1063	alcohol dehydrogenase
A8181_RS12175	COG2186	Transcriptional regulator
A8181_RS12185	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A8181_RS12190	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A8181_RS12215	COG1773	rubredoxin
A8181_RS12240	COG3781	membrane
A8181_RS12255	COG1012	belongs to the aldehyde dehydrogenase family
A8181_RS12260	COG0583	DNA-binding transcription factor activity
A8181_RS12295	COG2814	Major facilitator Superfamily
A8181_RS12300	COG3111	PFAM Bacterial OB fold (BOF) protein
A8181_RS12305	COG1546	Belongs to the CinA family
A8181_RS12310	COG3729	General stress protein
A8181_RS12325	COG4221	oxidoreductase activity
A8181_RS12330	COG1802	Transcriptional regulator
A8181_RS12340	COG0246	Mannitol dehydrogenase
A8181_RS12345	COG0477	Major facilitator Superfamily
A8181_RS12350	COG1063	alcohol dehydrogenase
A8181_RS12370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8181_RS12385	COG0243	molybdopterin cofactor binding
A8181_RS12390	COG0243	molybdopterin cofactor binding
A8181_RS12395	COG0437	4 iron, 4 sulfur cluster binding
A8181_RS12400	COG3302	dmso reductase anchor subunit
A8181_RS12440	COG1940	carbohydrate kinase activity
A8181_RS12450	COG0583	DNA-binding transcription factor activity
A8181_RS12455	COG2814	Major facilitator Superfamily
A8181_RS12465	COG3591	Belongs to the peptidase S1B family
A8181_RS12485	COG0628	permease
A8181_RS12490	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A8181_RS12495	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A8181_RS12510	COG0531	amino acid
A8181_RS12515	COG3136	membrane protein required for alginate biosynthesis
A8181_RS12520	COG0745	RESPONSE REGULATOR receiver
A8181_RS12530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A8181_RS12535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A8181_RS12540	COG2205	protein histidine kinase activity
A8181_RS12565	COG5339	Protein conserved in bacteria
A8181_RS12570	COG1263	PTS System
A8181_RS12570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8181_RS12580	COG0673	inositol 2-dehydrogenase activity
A8181_RS12630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A8181_RS12640	COG0625	glutathione transferase activity
A8181_RS12660	COG3895	Periplasmic Protein
A8181_RS12685	COG1566	PFAM secretion protein HlyD family protein
A8181_RS12700	COG4989	oxidoreductase activity
A8181_RS12705	COG3313	Fe-S protein
A8181_RS12710	COG1309	transcriptional regulator
A8181_RS12715	COG1902	pentaerythritol trinitrate reductase activity
A8181_RS12735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A8181_RS12740	COG0791	NLP P60 protein
A8181_RS12760	COG0583	DNA-binding transcription factor activity
A8181_RS12765	COG2814	Major facilitator Superfamily
A8181_RS12770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8181_RS12775	COG0307	riboflavin synthase, alpha
A8181_RS12945	COG3437	response regulator, receiver
A8181_RS12945	COG3850	Histidine kinase
A8181_RS12945	COG4999	Histidine kinase
A8181_RS12945	COG2205	protein histidine kinase activity
A8181_RS12950	COG2197	response regulator
A8181_RS12955	COG0789	Transcriptional regulator
A8181_RS12960	COG3272	Protein of unknown function (DUF1722)
A8181_RS12995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8181_RS13005	COG2267	carboxylic ester hydrolase activity
A8181_RS13010	COG0531	amino acid
A8181_RS13035	COG1376	ErfK ybiS ycfS ynhG family protein
A8181_RS13050	COG0719	Fe-S assembly protein
A8181_RS13055	COG0396	ATPase activity
A8181_RS13060	COG0719	Fe-S assembly protein
A8181_RS13065	COG0316	Belongs to the HesB IscA family
A8181_RS13070	COG1823	symporter activity
A8181_RS13080	COG2050	protein possibly involved in aromatic compounds catabolism
A8181_RS13085	COG0277	FAD linked oxidase domain protein
A8181_RS13085	COG0247	lactate metabolic process
A8181_RS13090	COG0628	permease
A8181_RS13105	COG0738	Major facilitator superfamily
A8181_RS13110	COG2271	Major facilitator Superfamily
A8181_RS13125	COG4670	ketone body catabolic process
A8181_RS13130	COG1960	acyl-CoA dehydrogenase activity
A8181_RS13135	COG1917	Cupin 2, conserved barrel domain protein
A8181_RS13135	COG2207	Transcriptional regulator
A8181_RS13140	COG2086	electron transfer activity
A8181_RS13145	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A8181_RS13150	COG0644	oxidoreductase
A8181_RS13155	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A8181_RS13160	COG0318	PFAM AMP-dependent synthetase and ligase
A8181_RS13165	COG0574	Belongs to the PEP-utilizing enzyme family
A8181_RS13165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A8181_RS13180	COG4256	Hemin uptake protein
A8181_RS13195	COG0791	NLP P60 protein
A8181_RS13205	COG0386	Belongs to the glutathione peroxidase family
A8181_RS13265	COG3137	Salt-induced outer membrane protein
A8181_RS13270	COG1105	Belongs to the carbohydrate kinase PfkB family
A8181_RS13280	COG3001	Fructosamine kinase
A8181_RS13290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8181_RS13295	COG1988	membrane-bound metal-dependent
A8181_RS13300	COG1823	symporter activity
A8181_RS13315	COG0753	catalase activity
A8181_RS13325	COG1486	melibiose metabolic process
A8181_RS13330	COG2169	Transcriptional regulator
A8181_RS13330	COG1917	Cupin 2, conserved barrel domain protein
A8181_RS13335	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8181_RS13340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8181_RS13345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8181_RS13355	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8181_RS13370	COG3678	ATP-independent chaperone mediated protein folding
A8181_RS13415	COG0494	nUDIX hydrolase
A8181_RS13440	COG0778	Nitroreductase
A8181_RS13445	COG0616	signal peptide processing
A8181_RS13450	COG0252	asparaginase activity
A8181_RS13455	COG1335	isochorismatase
A8181_RS13460	COG3139	Protein of unknown function (DUF1315)
A8181_RS13485	COG0656	L-ascorbic acid biosynthetic process
A8181_RS13490	COG0641	radical SAM
A8181_RS13495	COG3713	MltA-interacting MipA family protein
A8181_RS13500	COG2766	serine protein kinase
A8181_RS13515	COG2199	diguanylate cyclase activity
A8181_RS13520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8181_RS13535	COG2207	Transcriptional regulator
A8181_RS13540	COG2807	transmembrane transport
A8181_RS13545	COG3189	MarR family transcriptional regulator
A8181_RS13555	COG3042	response to heat
A8181_RS13560	COG2261	transglycosylase associated protein
A8181_RS13580	COG3615	Tellurite resistance protein tehB
A8181_RS13595	COG1605	Chorismate mutase
A8181_RS13605	COG0789	Transcriptional regulator
A8181_RS13620	COG3443	Belongs to the bacterial solute-binding protein 9 family
A8181_RS13635	COG0668	transmembrane transport
A8181_RS13640	COG1124	(ABC) transporter
A8181_RS13670	COG3038	cytochrome b561
A8181_RS13680	COG0071	Belongs to the small heat shock protein (HSP20) family
A8181_RS13755	COG0538	isocitrate dehydrogenase activity
A8181_RS13785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A8181_RS13800	COG2850	peptidyl-arginine hydroxylation
A8181_RS13835	COG1177	transmembrane transport
A8181_RS13855	COG4591	ABC-type transport system involved in lipoprotein release permease component
A8181_RS13860	COG1136	(ABC) transporter
A8181_RS13865	COG4591	ABC-type transport system involved in lipoprotein release permease component
A8181_RS13870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A8181_RS13885	COG1309	transcriptional regulator
A8181_RS13890	COG3134	Outer membrane lipoprotein
A8181_RS13895	COG1252	NADH dehydrogenase
A8181_RS13920	COG5633	Lipoprotein
A8181_RS13925	COG0537	adenosine 5'-monophosphoramidase activity
A8181_RS13930	COG4773	Receptor
A8181_RS13940	COG0084	hydrolase, TatD family'
A8181_RS13945	COG0470	DNA polymerase III
A8181_RS13955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A8181_RS13960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8181_RS13965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8181_RS14030	COG1530	ribonuclease E activity
A8181_RS14125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8181_RS14135	COG2999	glutathione oxidoreductase activity
A8181_RS14175	COG3038	cytochrome b561
A8181_RS14190	COG1560	Kdo2-lipid A biosynthetic process
A8181_RS14210	COG5645	(Lipo)protein
A8181_RS14235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8181_RS14295	COG3381	protein complex oligomerization
A8181_RS14320	COG0673	inositol 2-dehydrogenase activity
A8181_RS14325	COG2814	Major facilitator Superfamily
A8181_RS14350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8181_RS14355	COG1737	Transcriptional regulator
A8181_RS14360	COG1702	phosphate starvation-inducible protein PhoH
A8181_RS14390	COG1309	transcriptional regulator
A8181_RS14395	COG3729	General stress protein
A8181_RS14415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8181_RS14420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A8181_RS14420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A8181_RS14425	COG4232	protein-disulfide reductase activity
A8181_RS14480	COG3971	2-oxopent-4-enoate hydratase activity
A8181_RS14490	COG3384	dioxygenase
A8181_RS14495	COG1012	belongs to the aldehyde dehydrogenase family
A8181_RS14505	COG1846	Transcriptional regulator
A8181_RS14510	COG2368	4-hydroxyphenylacetate
A8181_RS14530	COG0745	RESPONSE REGULATOR receiver
A8181_RS14535	COG2205	protein histidine kinase activity
A8181_RS14585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A8181_RS14740	COG1783	phage Terminase large subunit
A8181_RS14755	COG3772	lysozyme
A8181_RS14815	COG0305	Participates in initiation and elongation during chromosome replication
A8181_RS14845	COG1396	sequence-specific DNA binding
A8181_RS14860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8181_RS14895	COG0670	Belongs to the BI1 family
A8181_RS14915	COG1881	PFAM PEBP family protein
A8181_RS14930	COG1832	CoA-binding protein
A8181_RS14945	COG0210	DNA helicase
A8181_RS14950	COG3304	Inner membrane component domain
A8181_RS14955	COG1289	transmembrane transporter activity
A8181_RS14960	COG3070	regulator of competence-specific genes
A8181_RS14980	COG1067	ATP-dependent peptidase activity
A8181_RS14990	COG3130	regulation of translation
A8181_RS14995	COG3009	Protein conserved in bacteria
A8181_RS15000	COG3008	intermembrane lipid transfer
A8181_RS15000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A8181_RS15005	COG2995	paraquat-inducible protein a
A8181_RS15010	COG0488	(ABC) transporter
A8181_RS15020	COG0633	Ferredoxin
A8181_RS15020	COG3217	Mosc domain protein beta barrel domain protein
A8181_RS15035	COG0308	aminopeptidase N
A8181_RS15055	COG2135	peptidase activity
A8181_RS15060	COG4372	Transposase
A8181_RS15080	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8181_RS15225	COG0484	heat shock protein binding
A8181_RS15270	COG1484	DNA-dependent DNA replication
A8181_RS15305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8181_RS15325	COG0582	viral genome integration into host DNA
A8181_RS15335	COG1115	amino acid carrier protein
A8181_RS15350	COG1522	sequence-specific DNA binding
A8181_RS15360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A8181_RS15370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8181_RS15375	COG3108	Peptidase M15
A8181_RS15395	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
A8181_RS15405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A8181_RS15410	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A8181_RS15415	COG3173	Aminoglycoside phosphotransferase
A8181_RS15430	COG3214	Protein conserved in bacteria
A8181_RS15445	COG2333	competence protein COMEC
A8181_RS15445	COG0658	competence protein
A8181_RS15455	COG0539	negative regulation of cytoplasmic translation
A8181_RS15465	COG0501	Belongs to the peptidase M48B family
A8181_RS15480	COG2323	membrane
A8181_RS15485	COG1944	ATP diphosphatase activity
A8181_RS15490	COG2116	formate transmembrane transporter activity
A8181_RS15495	COG1882	Formate acetyltransferase
A8181_RS15505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8181_RS15510	COG0531	amino acid
A8181_RS15520	COG3302	dmso reductase anchor subunit
A8181_RS15525	COG0437	4 iron, 4 sulfur cluster binding
A8181_RS15530	COG0243	molybdopterin cofactor binding
A8181_RS15540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A8181_RS15565	COG0492	ferredoxin-NADP+ reductase activity
A8181_RS15570	COG4988	ABC transporter
A8181_RS15575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A8181_RS15595	COG0583	DNA-binding transcription factor activity
A8181_RS15605	COG1335	isochorismatase
A8181_RS15630	COG0542	response to heat
A8181_RS15640	COG1278	Cold shock
A8181_RS15650	COG1136	(ABC) transporter
A8181_RS15650	COG0577	efflux transmembrane transporter activity
A8181_RS15655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8181_RS15660	COG2990	Protein conserved in bacteria
A8181_RS15665	COG3593	DNA synthesis involved in DNA repair
A8181_RS15675	COG2431	L-lysine efflux transmembrane transporter activity
A8181_RS15685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8181_RS15690	COG0028	Belongs to the TPP enzyme family
A8181_RS15695	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A8181_RS15700	COG0702	epimerase
A8181_RS15705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8181_RS15710	COG3023	N-Acetylmuramoyl-L-alanine amidase
A8181_RS15725	COG1126	abc transporter atp-binding protein
A8181_RS15730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8181_RS15735	COG4215	(ABC) transporter
A8181_RS15740	COG4160	amino acid transport
A8181_RS15745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8181_RS15780	COG1177	transmembrane transport
A8181_RS15785	COG1176	ABC-type spermidine putrescine transport system, permease component I
A8181_RS15790	COG3842	ATPase activity
A8181_RS15795	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A8181_RS15875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A8181_RS15980	COG4695	Portal protein
A8181_RS16025	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A8181_RS16065	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A8181_RS16070	COG3226	Transcriptional regulator
A8181_RS16075	COG0738	Major facilitator superfamily
A8181_RS16080	COG0561	phosphatase activity
A8181_RS16085	COG2814	Major facilitator Superfamily
A8181_RS16090	COG0671	phosphoesterase, PA-phosphatase related
A8181_RS16095	COG1349	DNA-binding transcription factor activity
A8181_RS16100	COG1686	Belongs to the peptidase S11 family
A8181_RS16105	COG0625	glutathione transferase activity
A8181_RS16120	COG2610	gluconate transmembrane transporter activity
A8181_RS16125	COG0583	DNA-binding transcription factor activity
A8181_RS16140	COG1960	acyl-CoA dehydrogenase activity
A8181_RS16160	COG2301	Belongs to the HpcH HpaI aldolase family
A8181_RS16215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8181_RS16220	COG1882	Formate acetyltransferase
A8181_RS16225	COG0561	phosphatase activity
A8181_RS16235	COG0561	phosphatase activity
A8181_RS16245	COG0488	(ABC) transporter
A8181_RS16250	COG1376	ErfK ybiS ycfS ynhG family protein
A8181_RS16255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8181_RS16270	COG2194	sulfuric ester hydrolase activity
A8181_RS16275	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A8181_RS16290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8181_RS16295	COG0765	amino acid transport
A8181_RS16300	COG1126	abc transporter atp-binding protein
A8181_RS16305	COG0668	transmembrane transport
A8181_RS16315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A8181_RS16325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8181_RS16335	COG0513	Belongs to the DEAD box helicase family
A8181_RS16340	COG1309	transcriptional regulator
A8181_RS16350	COG1131	(ABC) transporter
A8181_RS16355	COG0842	Transport permease protein
A8181_RS16360	COG0842	Transport permease protein
A8181_RS16370	COG3568	Endonuclease Exonuclease Phosphatase
A8181_RS16375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8181_RS16380	COG0392	lysyltransferase activity
A8181_RS16405	COG0670	Belongs to the BI1 family
A8181_RS16415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A8181_RS16425	COG0521	Mo-molybdopterin cofactor biosynthetic process
A8181_RS16455	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A8181_RS16480	COG1881	PFAM PEBP family protein
A8181_RS16575	COG1783	phage Terminase large subunit
A8181_RS16605	COG3772	lysozyme
A8181_RS16630	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A8181_RS16750	COG4712	double-strand break repair protein
A8181_RS16810	COG0582	viral genome integration into host DNA
A8181_RS16815	COG4677	pectinesterase activity
A8181_RS16825	COG0561	phosphatase activity
A8181_RS16835	COG4149	molybdate abc transporter
A8181_RS16840	COG0725	ABC transporter, periplasmic molybdate-binding protein
A8181_RS16850	COG3585	molybdate ion transport
A8181_RS16850	COG2005	Transcriptional regulator
A8181_RS16855	COG1119	ATPase activity
A8181_RS16880	COG2017	converts alpha-aldose to the beta-anomer
A8181_RS16895	COG1120	ATPase activity
A8181_RS16900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8181_RS16915	COG0511	ligase activity, forming carbon-carbon bonds
A8181_RS16915	COG5016	pyruvate
A8181_RS16925	COG0490	domain, Protein
A8181_RS16925	COG0471	metal ion transport
A8181_RS16930	COG0583	DNA-binding transcription factor activity
A8181_RS16935	COG0583	DNA-binding transcription factor activity
A8181_RS16945	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8181_RS16945	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8181_RS16950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8181_RS17010	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A8181_RS17015	COG2885	chlorophyll binding
A8181_RS17025	COG3064	Membrane
A8181_RS17030	COG0848	biopolymer transport protein
A8181_RS17035	COG0811	peptide transport
A8181_RS17040	COG0824	Thioesterase
A8181_RS17045	COG3790	cyd operon protein YbgE
A8181_RS17050	COG4890	Cyd operon protein YbgT
A8181_RS17055	COG1294	oxidase, subunit
A8181_RS17060	COG1271	oxidase subunit
A8181_RS17065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A8181_RS17075	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8181_RS17080	COG0567	Dehydrogenase, E1 component
A8181_RS17095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A8181_RS17120	COG3180	Ammonia monooxygenase
A8181_RS17140	COG1216	Glycosyl transferase, family 2
A8181_RS17180	COG0582	viral genome integration into host DNA
A8181_RS17195	COG1984	allophanate hydrolase subunit 2
A8181_RS17200	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A8181_RS17250	COG2205	protein histidine kinase activity
A8181_RS17255	COG0745	RESPONSE REGULATOR receiver
A8181_RS17260	COG1982	Orn Lys Arg decarboxylase major
A8181_RS17265	COG0531	amino acid
A8181_RS17280	COG0596	Alpha beta hydrolase
A8181_RS17295	COG0735	belongs to the Fur family
A8181_RS17300	COG0583	DNA-binding transcription factor activity
A8181_RS17305	COG1053	succinate dehydrogenase
A8181_RS17345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A8181_RS17350	COG1846	Transcriptional regulator
A8181_RS17350	COG1940	carbohydrate kinase activity
A8181_RS17355	COG0647	UMP catabolic process
A8181_RS17365	COG0367	asparagine synthase
A8181_RS17410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8181_RS17420	COG1702	phosphate starvation-inducible protein PhoH
A8181_RS17445	COG0765	amino acid transport
A8181_RS17450	COG0765	amino acid transport
A8181_RS17455	COG1126	abc transporter atp-binding protein
A8181_RS17470	COG0443	Heat shock 70 kDa protein
A8181_RS17475	COG2214	Heat shock protein DnaJ domain protein
A8181_RS17485	COG2214	Heat shock protein DnaJ domain protein
A8181_RS17500	COG2888	peptidyl-tyrosine sulfation
A8181_RS17505	COG3829	transcription factor binding
A8181_RS17505	COG3290	protein histidine kinase activity
A8181_RS17535	COG1466	dna polymerase III delta subunit
A8181_RS17555	COG0799	negative regulation of ribosome biogenesis
A8181_RS17565	COG0768	penicillin binding
A8181_RS17570	COG0772	Belongs to the SEDS family
A8181_RS17575	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A8181_RS17580	COG1686	Belongs to the peptidase S11 family
A8181_RS17595	COG0583	DNA-binding transcription factor activity
A8181_RS17610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8181_RS17630	COG3069	C4-dicarboxylate transmembrane transporter activity
A8181_RS17635	COG4565	transcriptional regulatory protein
A8181_RS17640	COG3290	protein histidine kinase activity
A8181_RS17650	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
A8181_RS17660	COG2301	Belongs to the HpcH HpaI aldolase family
A8181_RS17665	COG3051	citrate lyase alpha subunit
A8181_RS17680	COG0471	metal ion transport
A8181_RS17685	COG3719	Belongs to the RNase T2 family
A8181_RS17695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8181_RS17700	COG1063	alcohol dehydrogenase
A8181_RS17725	COG0243	molybdopterin cofactor binding
A8181_RS17745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A8181_RS17750	COG0583	DNA-binding transcription factor activity
A8181_RS17755	COG3969	phosphoadenosine phosphosulfate
A8181_RS17760	COG1475	DNA binding
A8181_RS17765	COG0436	Aminotransferase
A8181_RS17770	COG0371	Dehydrogenase
A8181_RS17775	COG2879	small protein
A8181_RS17780	COG1966	Carbon starvation protein
A8181_RS17790	COG1028	Short-chain dehydrogenase reductase Sdr
A8181_RS17795	COG3433	isochorismatase activity
A8181_RS17795	COG1535	isochorismatase
A8181_RS17800	COG1021	2,3-dihydroxybenzoate-AMP ligase
A8181_RS17805	COG1169	isochorismate synthase
A8181_RS17810	COG4592	Periplasmic binding protein
A8181_RS17820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8181_RS17825	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8181_RS17830	COG1120	ATPase activity
A8181_RS17835	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A8181_RS17840	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A8181_RS17840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8181_RS17845	COG3251	PFAM MbtH domain protein
A8181_RS17850	COG2382	esterase
A8181_RS17855	COG4771	TonB-dependent receptor
A8181_RS17885	COG2315	Protein conserved in bacteria
A8181_RS17910	COG3716	PTS system mannose fructose sorbose family IID component
A8181_RS17920	COG2222	sugar isomerase
A8181_RS17925	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A8181_RS17925	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A8181_RS17940	COG0668	transmembrane transport
A8181_RS17945	COG1113	amino acid transport
A8181_RS17955	COG3059	membrane
A8181_RS17965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8181_RS17970	COG2207	Transcriptional regulator
A8181_RS17975	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8181_RS17980	COG5002	protein histidine kinase activity
A8181_RS17990	COG2246	polysaccharide biosynthetic process
A8181_RS17995	COG0463	Glycosyl transferase, family 2
A8181_RS18080	COG2501	S4 domain
A8181_RS18085	COG1988	membrane-bound metal-dependent
A8181_RS18105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A8181_RS18120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A8181_RS18125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A8181_RS18130	COG0549	Belongs to the carbamate kinase family
A8181_RS18140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A8181_RS18145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A8181_RS18150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A8181_RS18155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8181_RS18160	COG3257	ureidoglycine aminohydrolase activity
A8181_RS18165	COG1929	Belongs to the glycerate kinase type-1 family
A8181_RS18170	COG2233	PERMEase
A8181_RS18180	COG1953	Uracil, thiamine, allantoin
A8181_RS18190	COG2084	Dehydrogenase
A8181_RS18195	COG3622	Belongs to the hyi family
A8181_RS18200	COG3960	tartronate-semialdehyde synthase activity
A8181_RS18235	COG1464	Belongs to the NlpA lipoprotein family
A8181_RS18245	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A8181_RS18250	COG4181	ATPase activity
A8181_RS18255	COG2755	lipolytic protein G-D-S-L family
A8181_RS18260	COG0300	oxidoreductase activity
A8181_RS18265	COG3118	belongs to the thioredoxin family
A8181_RS18270	COG0390	transport system, permease component
A8181_RS18275	COG4619	ABC transporter
A8181_RS18280	COG0330	HflC and HflK could
A8181_RS18285	COG1585	Membrane protein implicated in regulation of membrane protease activity
A8181_RS18295	COG2217	Heavy metal translocating P-type atpase
A8181_RS18305	COG3735	TraB family
A8181_RS18320	COG2223	nitrite transmembrane transporter activity
A8181_RS18325	COG4651	solute:proton antiporter activity
A8181_RS18325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A8181_RS18330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8181_RS18390	COG2832	Protein of unknown function (DUF454)
A8181_RS18395	COG3923	Primosomal replication protein n
A8181_RS18405	COG5464	transposase or invertase
A8181_RS18410	COG1196	nuclear chromosome segregation
A8181_RS18410	COG3264	Mechanosensitive ion channel
A8181_RS18415	COG1309	transcriptional regulator
A8181_RS18420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8181_RS18425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8181_RS18440	COG0110	maltose O-acetyltransferase activity
A8181_RS18460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A8181_RS18470	COG3695	enzyme binding
A8181_RS18475	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A8181_RS18480	COG1946	Acyl-CoA thioesterase
A8181_RS18485	COG0004	ammonium transporteR
A8181_RS18490	COG0347	Belongs to the P(II) protein family
A8181_RS18495	COG1132	(ABC) transporter
A8181_RS18500	COG1132	(ABC) transporter
A8181_RS18505	COG1522	sequence-specific DNA binding
A8181_RS18520	COG4533	DNA binding
A8181_RS18530	COG0824	Thioesterase
A8181_RS18535	COG1555	photosystem II stabilization
A8181_RS18540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8181_RS18550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A8181_RS18575	COG0271	Belongs to the BolA IbaG family
A8181_RS18585	COG3056	Lipoprotein
A8181_RS18590	COG2223	nitrite transmembrane transporter activity
A8181_RS18595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A8181_RS18600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A8181_RS18605	COG1845	cytochrome c oxidase, subunit III
A8181_RS18610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A8181_RS18635	COG2814	Major facilitator Superfamily
A8181_RS18665	COG2188	Transcriptional regulator
A8181_RS18700	COG0142	geranyltranstransferase activity
A8181_RS18710	COG0667	Aldo Keto reductase
A8181_RS18715	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A8181_RS18720	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A8181_RS18735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8181_RS18735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8181_RS18745	COG4238	major outer membrane lipoprotein
A8181_RS18780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A8181_RS18790	COG1862	Preprotein translocase
A8181_RS18815	COG0450	alkyl hydroperoxide reductase
A8181_RS18820	COG0366	Alpha amylase catalytic
A8181_RS18835	COG5002	protein histidine kinase activity
A8181_RS18845	COG0420	3'-5' exonuclease activity
A8181_RS18850	COG0419	ATPase involved in DNA repair
A8181_RS18855	COG2814	Major facilitator Superfamily
A8181_RS18860	COG1940	carbohydrate kinase activity
A8181_RS18875	COG4126	flavin adenine dinucleotide binding
A8181_RS18895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8181_RS18900	COG3706	GGDEF domain
A8181_RS18945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A8181_RS18955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8181_RS18970	COG0113	porphobilinogen synthase activity
A8181_RS19005	COG1280	lysine exporter protein (LysE YggA)
A8181_RS19025	COG1294	oxidase, subunit
A8181_RS19030	COG1271	oxidase subunit
A8181_RS19045	COG2814	Major facilitator Superfamily
A8181_RS19055	COG0789	Transcriptional regulator
A8181_RS19060	COG2217	Heavy metal translocating P-type atpase
A8181_RS19110	COG2200	EAL domain
A8181_RS19130	COG3539	Fimbrial protein
A8181_RS19135	COG3121	Chaperone
A8181_RS19140	COG3188	usher protein
A8181_RS19170	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8181_RS19185	COG2814	Major facilitator Superfamily
A8181_RS19200	COG2801	Transposase and inactivated derivatives
A8181_RS19240	COG2195	Cleaves the N-terminal amino acid of tripeptides
A8181_RS19245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A8181_RS19250	COG1690	Belongs to the RtcB family
A8181_RS19260	COG3034	peptidoglycan biosynthetic process
A8181_RS19265	COG0121	glutamine amidotransferase
A8181_RS19280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8181_RS19465	COG2885	chlorophyll binding
A8181_RS19465	COG3047	cAMP biosynthetic process
A8181_RS19575	COG2226	methyltransferase
A8181_RS19585	COG1388	LysM domain
A8181_RS19585	COG0741	lytic transglycosylase activity
A8181_RS19590	COG2226	methyltransferase
A8181_RS19600	COG2814	Major facilitator Superfamily
A8181_RS19605	COG0583	DNA-binding transcription factor activity
A8181_RS19645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A8181_RS19670	COG1720	tRNA m6t6A37 methyltransferase activity
A8181_RS19680	COG3015	lipoprotein NlpE involved in copper resistance
A8181_RS19685	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A8181_RS19700	COG4568	rho-dependent transcription termination
A8181_RS19710	COG0346	lactoylglutathione lyase activity
A8181_RS19715	COG1982	Orn Lys Arg decarboxylase major
A8181_RS19775	COG0575	Belongs to the CDS family
A8181_RS19845	COG3835	regulator
A8181_RS19870	COG2860	membrane
A8181_RS19900	COG3539	Fimbrial protein
A8181_RS19905	COG3539	Fimbrial protein
A8181_RS19910	COG3121	Chaperone
A8181_RS19915	COG3188	usher protein
A8181_RS19940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8181_RS19945	COG1120	ATPase activity
A8181_RS19950	COG4774	siderophore transport
A8181_RS19955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8181_RS19965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A8181_RS19990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A8181_RS20015	COG0726	polysaccharide deacetylase
A8181_RS20020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS20040	COG3539	Fimbrial protein
A8181_RS20045	COG0842	Transport permease protein
A8181_RS20050	COG1131	(ABC) transporter
A8181_RS20055	COG0288	reversible hydration of carbon dioxide
A8181_RS20065	COG4993	Dehydrogenase
A8181_RS20070	COG2132	Multicopper oxidase
A8181_RS20090	COG1349	DNA-binding transcription factor activity
A8181_RS20130	COG3064	Membrane
A8181_RS20145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8181_RS20150	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8181_RS20155	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A8181_RS20170	COG2211	Major facilitator Superfamily
A8181_RS20175	COG3940	Belongs to the glycosyl hydrolase 43 family
A8181_RS20180	COG3725	Membrane protein required for beta-lactamase induction
A8181_RS20200	COG4969	Belongs to the N-Me-Phe pilin family
A8181_RS20205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A8181_RS20210	COG1459	type II secretion system
A8181_RS20245	COG0494	nUDIX hydrolase
A8181_RS20265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A8181_RS20270	COG0849	cell division
A8181_RS20295	COG0772	Belongs to the SEDS family
A8181_RS20310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A8181_RS20320	COG0768	penicillin binding
A8181_RS20405	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
A8181_RS20410	COG0586	Pfam SNARE associated Golgi protein
A8181_RS20440	COG0675	Transposase, IS605 OrfB family
A8181_RS20465	COG0417	DNA replication proofreading
A8181_RS20495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A8181_RS20540	COG3119	arylsulfatase activity
A8181_RS20565	COG2271	Major facilitator Superfamily
A8181_RS20575	COG0644	oxidoreductase
A8181_RS20720	COG1047	Peptidyl-prolyl cis-trans
A8181_RS20735	COG0196	riboflavin kinase activity
A8181_RS20760	COG0583	DNA-binding transcription factor activity
A8181_RS20780	COG0641	radical SAM
A8181_RS20785	COG3119	arylsulfatase activity
A8181_RS20795	COG0737	Belongs to the 5'-nucleotidase family
A8181_RS20810	COG0583	DNA-binding transcription factor activity
A8181_RS20830	COG3121	Chaperone
A8181_RS20835	COG3539	Fimbrial protein
A8181_RS20850	COG3188	usher protein
A8181_RS20915	COG4735	regulation of single-species biofilm formation
A8181_RS20920	COG1584	GPR1 FUN34 yaaH family protein
A8181_RS20925	COG0521	Mo-molybdopterin cofactor biosynthetic process
A8181_RS20935	COG1115	amino acid carrier protein
A8181_RS20945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A8181_RS20955	COG0527	aspartate kinase activity
A8181_RS20955	COG0460	homoserine dehydrogenase
A8181_RS20965	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A8181_RS20975	COG0745	RESPONSE REGULATOR receiver
A8181_RS20995	COG3121	Chaperone
A8181_RS21015	COG4452	Inner membrane protein CreD
A8181_RS21020	COG2205	protein histidine kinase activity
A8181_RS21025	COG0745	RESPONSE REGULATOR receiver
A8181_RS21030	COG3045	CreA protein
A8181_RS21035	COG3708	Transcriptional regulator
A8181_RS21035	COG2207	Transcriptional regulator
A8181_RS21065	COG0488	(ABC) transporter
A8181_RS21080	COG0560	Phosphoserine phosphatase
A8181_RS21090	COG3726	membrane protein affecting hemolysin expression
A8181_RS21105	COG3539	Fimbrial protein
A8181_RS21110	COG3121	Chaperone
A8181_RS21115	COG3188	usher protein
A8181_RS21145	COG1328	CTP reductase activity
A8181_RS21150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8181_RS21155	COG0084	hydrolase, TatD family'
A8181_RS21170	COG2823	Periplasmic or secreted lipoprotein
A8181_RS21180	COG1011	Hydrolase
A8181_RS21190	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A8181_RS21220	COG3706	GGDEF domain
A8181_RS21225	COG4114	ferric iron reductase
A8181_RS21230	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8181_RS21235	COG2197	response regulator
A8181_RS21240	COG2197	response regulator
A8181_RS21245	COG2966	Psort location CytoplasmicMembrane, score
A8181_RS21260	COG1484	DNA-dependent DNA replication
A8181_RS21280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A8181_RS21285	COG3716	PTS system mannose fructose sorbose family IID component
A8181_RS21290	COG3715	PTS system
A8181_RS21295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8181_RS21310	COG0840	transmembrane signaling receptor activity
A8181_RS21315	COG1966	Carbon starvation protein
A8181_RS21320	COG2879	small protein
A8181_RS21325	COG0523	cobalamin synthesis protein
A8181_RS21345	COG0732	type I restriction modification DNA specificity domain
A8181_RS21360	COG3586	endonuclease activity
A8181_RS21370	COG1012	belongs to the aldehyde dehydrogenase family
A8181_RS21375	COG5464	transposase or invertase
A8181_RS21385	COG2733	membrane
A8181_RS21400	COG3366	ferrous iron transmembrane transporter activity
A8181_RS21405	COG0700	Nucleoside recognition
A8181_RS21410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A8181_RS21415	COG0583	DNA-binding transcription factor activity
A8181_RS21440	COG2186	Transcriptional regulator
A8181_RS21450	COG0412	Dienelactone hydrolase
A8181_RS21485	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A8181_RS21560	COG1204	response to ionizing radiation
A8181_RS21575	COG1064	alcohol dehydrogenase
A8181_RS21580	COG3265	gluconokinase activity
A8181_RS21585	COG1063	alcohol dehydrogenase
A8181_RS21590	COG1028	Short-chain dehydrogenase reductase Sdr
A8181_RS21595	COG2610	gluconate transmembrane transporter activity
A8181_RS21600	COG1609	Transcriptional regulator
A8181_RS21605	COG0795	lipopolysaccharide-transporting ATPase activity
A8181_RS21610	COG0795	lipopolysaccharide-transporting ATPase activity
A8181_RS21625	COG2927	DNA polymerase III (CHI subunit)
A8181_RS21665	COG2731	YhcH YjgK YiaL family protein
A8181_RS21695	COG1288	antiporter activity
A8181_RS21700	COG1438	arginine binding
A8181_RS21735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8181_RS21735	COG1263	PTS System
A8181_RS21740	COG0366	Alpha amylase catalytic
A8181_RS21755	COG2026	Addiction module toxin, RelE StbE family
A8181_RS21760	COG3077	Addiction module antitoxin, RelB DinJ family
A8181_RS21765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS21765	COG3711	transcriptional antiterminator
A8181_RS21780	COG3964	amidohydrolase
A8181_RS21815	COG0312	modulator of DNA gyrase
A8181_RS21825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A8181_RS21840	COG3964	amidohydrolase
A8181_RS21845	COG2271	Major facilitator Superfamily
A8181_RS21850	COG2105	PFAM AIG2 family protein
A8181_RS21870	COG1253	flavin adenine dinucleotide binding
A8181_RS21885	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A8181_RS21905	COG1733	regulation of RNA biosynthetic process
A8181_RS21910	COG0702	epimerase
A8181_RS21915	COG0697	spore germination
A8181_RS21935	COG1113	amino acid transport
A8181_RS21940	COG0545	Peptidyl-prolyl cis-trans isomerase
A8181_RS21945	COG3061	Opacity-associated protein A
A8181_RS21960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A8181_RS22025	COG1073	alpha beta
A8181_RS22030	COG3650	response to hydrogen peroxide
A8181_RS22040	COG1960	acyl-CoA dehydrogenase activity
A8181_RS22045	COG0754	glutathionylspermidine amidase activity
A8181_RS22050	COG5463	Belongs to the UPF0441 family
A8181_RS22055	COG3766	membrane
A8181_RS22070	COG1842	Phage shock protein A
A8181_RS22075	COG3789	protein conserved in bacteria
A8181_RS22100	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A8181_RS22105	COG0330	HflC and HflK could
A8181_RS22110	COG0330	HflC and HflK could
A8181_RS22115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A8181_RS22140	COG0802	atpase or kinase
A8181_RS22145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A8181_RS22145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A8181_RS22170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8181_RS22190	COG1511	domain protein
A8181_RS22190	COG3264	Mechanosensitive ion channel
A8181_RS22210	COG1053	succinate dehydrogenase
A8181_RS22215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A8181_RS22245	COG5510	response to toxic substance
A8181_RS22285	COG0531	amino acid
A8181_RS22290	COG3030	protein affecting phage T7 exclusion by the F plasmid
A8181_RS22300	COG1027	Aspartate ammonia-lyase
A8181_RS22305	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8181_RS22320	COG1309	transcriptional regulator
A8181_RS22405	COG2801	Transposase and inactivated derivatives
A8181_RS22430	COG2197	response regulator
A8181_RS22435	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
A8181_RS22455	COG3381	protein complex oligomerization
A8181_RS22460	COG3302	dmso reductase anchor subunit
A8181_RS22465	COG0437	4 iron, 4 sulfur cluster binding
A8181_RS22470	COG0243	molybdopterin cofactor binding
A8181_RS22475	COG3290	protein histidine kinase activity
A8181_RS22480	COG4565	transcriptional regulatory protein
A8181_RS22490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8181_RS22495	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8181_RS22495	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8181_RS22510	COG2169	Transcriptional regulator
A8181_RS22515	COG1982	Orn Lys Arg decarboxylase major
A8181_RS22520	COG2207	Transcriptional regulator
A8181_RS22525	COG0531	amino acid
A8181_RS22550	COG2824	Alkylphosphonate utilization operon protein PhnA
A8181_RS22555	COG2764	glyoxalase bleomycin resistance protein dioxygenase
A8181_RS22570	COG3383	formate dehydrogenase (NAD+) activity
A8181_RS22575	COG3383	formate dehydrogenase (NAD+) activity
A8181_RS22580	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A8181_RS22585	COG1301	dicarboxylic acid transport
A8181_RS22590	COG4235	cytochrome complex assembly
A8181_RS22595	COG1138	Cytochrome C-type biogenesis protein
A8181_RS22600	COG3301	Polysulphide reductase, NrfD
A8181_RS22605	COG0437	4 iron, 4 sulfur cluster binding
A8181_RS22610	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A8181_RS22625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A8181_RS22630	COG3162	membrane
A8181_RS22640	COG1346	cytolysis
A8181_RS22645	COG1380	Effector of murein hydrolase LrgA
A8181_RS22650	COG0583	DNA-binding transcription factor activity
A8181_RS22655	COG0025	NhaP-type Na H and K H
A8181_RS22665	COG2252	PERMEase
A8181_RS22695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A8181_RS22760	COG2315	Protein conserved in bacteria
A8181_RS22810	COG0735	belongs to the Fur family
A8181_RS22820	COG0534	Mate efflux family protein
A8181_RS22830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A8181_RS22870	COG1175	transmembrane transport
A8181_RS22875	COG3833	ABC-type maltose transport systems, permease component
A8181_RS22885	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8181_RS22910	COG0527	aspartate kinase activity
A8181_RS22995	COG2246	polysaccharide biosynthetic process
A8181_RS23025	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8181_RS23030	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A8181_RS23045	COG0561	phosphatase activity
A8181_RS23050	COG1349	DNA-binding transcription factor activity
A8181_RS23065	COG3122	Protein conserved in bacteria
A8181_RS23105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A8181_RS23150	COG0151	Belongs to the GarS family
A8181_RS23215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8181_RS23220	COG2104	thiamine diphosphate biosynthetic process
A8181_RS23290	COG0250	Participates in transcription elongation, termination and antitermination
A8181_RS23335	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A8181_RS23400	COG0583	DNA-binding transcription factor activity
A8181_RS23440	COG2207	Transcriptional regulator
A8181_RS23445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8181_RS23450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8181_RS23455	COG1882	Formate acetyltransferase
A8181_RS23460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8181_RS23465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8181_RS23470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A8181_RS23470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS23470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8181_RS23480	COG0371	Dehydrogenase
A8181_RS23485	COG3738	Protein conserved in bacteria
A8181_RS23500	COG0737	Belongs to the 5'-nucleotidase family
A8181_RS23515	COG0668	transmembrane transport
A8181_RS23520	COG0527	aspartate kinase activity
A8181_RS23520	COG0460	homoserine dehydrogenase
A8181_RS23525	COG0626	cystathionine gamma-synthase activity
A8181_RS23550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A8181_RS23555	COG1609	Transcriptional regulator
A8181_RS23560	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A8181_RS23575	COG1575	Belongs to the MenA family. Type 1 subfamily
A8181_RS23590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A8181_RS23600	COG1494	fructose-1,6-bisphosphatase
A8181_RS23610	COG3152	Membrane
A8181_RS23665	COG1070	Carbohydrate kinase
A8181_RS23675	COG2134	cdp-diacylglycerol pyrophosphatase
A8181_RS23680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8181_RS23690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8181_RS23695	COG2211	Major facilitator Superfamily
A8181_RS23770	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8181_RS23770	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8181_RS23860	COG4695	Portal protein
A8181_RS23930	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A8181_RS23935	COG3678	ATP-independent chaperone mediated protein folding
A8181_RS23940	COG0745	RESPONSE REGULATOR receiver
A8181_RS23945	COG2205	protein histidine kinase activity
A8181_RS23960	COG2258	MOSC domain
A8181_RS23965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A8181_RS23975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A8181_RS24020	COG1454	alcohol dehydrogenase
A8181_RS24035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A8181_RS24060	COG0243	molybdopterin cofactor binding
A8181_RS24060	COG3383	formate dehydrogenase (NAD+) activity
A8181_RS24065	COG0243	molybdopterin cofactor binding
A8181_RS24065	COG3383	formate dehydrogenase (NAD+) activity
A8181_RS24070	COG0437	4 iron, 4 sulfur cluster binding
A8181_RS24075	COG2864	formate dehydrogenase
A8181_RS24090	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
A8181_RS24100	COG4680	protein conserved in bacteria
A8181_RS24105	COG5499	transcription regulator containing HTH domain
A8181_RS24110	COG0456	acetyltransferase
A8181_RS24125	COG1011	Hydrolase
A8181_RS24130	COG1349	DNA-binding transcription factor activity
A8181_RS24135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8181_RS24145	COG3684	Belongs to the aldolase LacD family
A8181_RS24155	COG2017	converts alpha-aldose to the beta-anomer
A8181_RS24165	COG1501	Belongs to the glycosyl hydrolase 31 family
A8181_RS24175	COG2211	Major facilitator Superfamily
A8181_RS24255	COG0204	Acyl-transferase
A8181_RS24270	COG3084	Protein conserved in bacteria
A8181_RS24280	COG1763	Mo-molybdopterin cofactor biosynthetic process
A8181_RS24325	COG1739	Uncharacterized protein family UPF0029
A8181_RS24355	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8181_RS24370	COG0805	protein transport
A8181_RS24415	COG0641	radical SAM
A8181_RS24435	COG0561	phosphatase activity
A8181_RS24440	COG2267	carboxylic ester hydrolase activity
A8181_RS24450	COG1280	lysine exporter protein (LysE YggA)
A8181_RS24500	COG1011	Hydrolase
A8181_RS24565	COG2959	enzyme of heme biosynthesis
A8181_RS24570	COG3071	HemY protein
A8181_RS24615	COG2244	polysaccharide biosynthetic process
A8181_RS24620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A8181_RS24625	COG0456	acetyltransferase
A8181_RS24630	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A8181_RS24630	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A8181_RS24635	COG1088	dTDP-glucose 4,6-dehydratase activity
A8181_RS24640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A8181_RS24665	COG3118	belongs to the thioredoxin family
A8181_RS24735	COG3978	acetolactate synthase activity
A8181_RS24795	COG2186	Transcriptional regulator
A8181_RS24800	COG0477	Major facilitator Superfamily
A8181_RS24805	COG1609	Transcriptional regulator
A8181_RS24810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8181_RS24820	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8181_RS24855	COG1522	sequence-specific DNA binding
A8181_RS24860	COG0716	FMN binding
A8181_RS24875	COG3312	ion transport
A8181_RS24940	COG4533	DNA binding
A8181_RS24945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A8181_RS24950	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A8181_RS24950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8181_RS24950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8181_RS24955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A8181_RS24960	COG0573	inorganic phosphate transmembrane transporter activity
A8181_RS24965	COG0581	inorganic phosphate transmembrane transporter activity
A8181_RS24975	COG0704	Plays a role in the regulation of phosphate uptake
A8181_RS24980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8181_RS24985	COG2252	PERMEase
A8181_RS24990	COG0431	NADPH-dependent FMN reductase
A8181_RS24995	COG2091	lysine biosynthetic process via aminoadipic acid
A8181_RS25150	COG3005	denitrification pathway
A8181_RS25170	COG0243	molybdopterin cofactor binding
A8181_RS25190	COG1858	cytochrome C peroxidase
A8181_RS25260	COG4235	cytochrome complex assembly
A8181_RS25260	COG3088	subunit of a heme lyase
A8181_RS25355	COG2814	Major facilitator Superfamily
A8181_RS25360	COG2814	Major facilitator Superfamily
A8181_RS25385	COG0028	Belongs to the TPP enzyme family
A8181_RS25675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8181_RS25715	COG1561	YicC-like family, N-terminal region