locus-tag class description FGF60_RS00005 ENOG4105CFH Aspartokinase FGF60_RS00015 ENOG4105D98 threonine synthase FGF60_RS00025 ENOG4105BZG amino acid carrier protein FGF60_RS00030 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FGF60_RS00035 ENOG4108RIR Molybdenum cofactor biosynthesis protein FGF60_RS00040 ENOG4106HK8 GPR1 FUN34 yaaH family protein FGF60_RS00045 ENOG4108QUJ UPF0174 protein YaaW FGF60_RS00050 ENOG4108WTA UPF0412 protein YaaI FGF60_RS00105 ENOG4108AF8 Chaperone FGF60_RS00110 ENOG4105CW0 outer membrane usher protein FGF60_RS00115 ENOG4105MHR Fimbrial protein FGF60_RS00130 ENOG4106PH7 chaperone FGF60_RS00150 ENOG4105DQS Transcriptional regulator FGF60_RS00165 ENOG4105CGH 5'-nucleotidase FGF60_RS00175 ENOG41061MV Arylsulfatase FGF60_RS00180 ENOG4105C4X radical SAM domain protein FGF60_RS00200 ENOG41063Z6 transcriptional regulator, lysR family FGF60_RS00220 ENOG410647N response to DNA damage stimulus FGF60_RS00225 ENOG4105DTN riboflavin biosynthesis protein ribF FGF60_RS00230 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FGF60_RS00240 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FGF60_RS00260 ENOG4106YYS transcriptional regulatory protein FGF60_RS00265 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FGF60_RS00270 ENOG4105D9Q decarboxylase (Beta subunit) FGF60_RS00280 ENOG4106AFN Lyase and sodium transporter (By similarity) FGF60_RS00285 ENOG4105D2K citrate carrier protein FGF60_RS00290 ENOG4105DUA (citrate (pro-3S)-lyase ligase FGF60_RS00300 ENOG4105CI0 Citrate lyase FGF60_RS00305 ENOG4105CHY citrate lyase, alpha FGF60_RS00320 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) FGF60_RS00330 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FGF60_RS00335 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FGF60_RS00340 ENOG4108XNW Transcriptional activatory protein CaiF FGF60_RS00345 ENOG4108Z0R Transferase FGF60_RS00385 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FGF60_RS00390 ENOG4105WQV ferredoxin-like protein FGF60_RS00395 ENOG4105C54 Major Facilitator superfamily FGF60_RS00400 ENOG4105M5B (LipO)protein FGF60_RS00420 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF FGF60_RS00425 ENOG4105CKD glutathione-regulated potassium-efflux system protein FGF60_RS00440 ENOG4105NWN ApaG protein FGF60_RS00450 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) FGF60_RS00460 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FGF60_RS00470 ENOG4105D3G Pseudouridine synthase FGF60_RS00475 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FGF60_RS00480 ENOG4105CQ2 DNA polymerase FGF60_RS00500 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FGF60_RS00510 ENOG4105EF1 ribulokinase FGF60_RS00515 ENOG41063TF transcriptional regulator (AraC FGF60_RS00520 ENOG4108KF1 Membrane FGF60_RS00525 ENOG4107T0D ABC, transporter FGF60_RS00540 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FGF60_RS00550 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FGF60_RS00555 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FGF60_RS00560 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FGF60_RS00575 ENOG41064T2 transcriptional regulator, lysR family FGF60_RS00580 ENOG4105C7K acetolactate synthase FGF60_RS00585 ENOG4108ZP8 Acetolactate synthase small subunit FGF60_RS00590 ENOG4107B7Y DNA-binding transcriptional regulator FruR FGF60_RS00605 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FGF60_RS00610 ENOG4105CJN penicillin-binding protein FGF60_RS00615 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FGF60_RS00620 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FGF60_RS00630 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FGF60_RS00635 ENOG4105CNI cell division protein FtsW FGF60_RS00650 ENOG4105CPF Cell wall formation (By similarity) FGF60_RS00655 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FGF60_RS00660 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FGF60_RS00665 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FGF60_RS00675 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) FGF60_RS00685 ENOG4105M6F mutator MutT protein FGF60_RS00710 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FGF60_RS00720 ENOG4105D7Q type ii secretion system FGF60_RS00725 ENOG4107QHF type ii secretion system protein e FGF60_RS00730 ENOG4108ZUW Major pilin subunit FGF60_RS00735 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FGF60_RS00745 ENOG4106A72 regulatory protein AmpE FGF60_RS00750 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) FGF60_RS00755 ENOG4105CT4 transporter FGF60_RS00770 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FGF60_RS00775 ENOG4107QSN dihydrolipoamide acetyltransferase FGF60_RS00780 ENOG4107QN2 dihydrolipoyl dehydrogenase FGF60_RS00795 ENOG4108NST exported protein FGF60_RS00800 ENOG4107QIJ Aconitate hydratase 2 FGF60_RS00815 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) FGF60_RS00820 ENOG4107S2N Type III effector Hrp-dependent FGF60_RS00825 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) FGF60_RS00830 ENOG4105MVE transcriptional regulator FGF60_RS00845 ENOG4108ZRK uncharacterized protein yacC FGF60_RS00850 ENOG4105E3B Multicopper oxidase FGF60_RS00855 ENOG4105DZG Dehydrogenase FGF60_RS00860 ENOG4108UGV hypoxanthine phosphoribosyltransferase FGF60_RS00865 ENOG41077A9 carbonic anhydrase FGF60_RS00870 ENOG4105DA5 (ABC) transporter FGF60_RS00875 ENOG4105E3A (ABC) transporter FGF60_RS00880 ENOG4108MDY Fimbrial FGF60_RS00885 ENOG4105CW0 outer membrane usher protein FGF60_RS00890 ENOG4108UIF Chaperone FGF60_RS00900 ENOG4108YTN IIa component FGF60_RS00905 ENOG4107BJW polysaccharide deacetylase FGF60_RS00915 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) FGF60_RS00925 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FGF60_RS00930 ENOG4105DJ0 Poly(A) Polymerase FGF60_RS00935 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) FGF60_RS00940 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters FGF60_RS00950 ENOG4107XID 2'-5' rna ligase FGF60_RS00955 ENOG4105CQ7 ATP-dependent helicase FGF60_RS00960 ENOG4105BZ4 penicillin-binding protein FGF60_RS00965 ENOG4105E0K tonB-dependent siderophore receptor FGF60_RS00970 ENOG4105E0A ABC, transporter FGF60_RS00975 ENOG4105J76 Periplasmic binding protein FGF60_RS00980 ENOG4105S6R Iron-hydroxamate transporter permease subunit FGF60_RS00990 ENOG4106PG1 outer membrane usher protein FGF60_RS00995 ENOG4108FZ9 Chaperone FGF60_RS01000 ENOG4105NEV Fimbrial FGF60_RS01005 ENOG4105UGQ Fimbrial FGF60_RS01015 ENOG4106RDH Protein of unknown function (DUF2544) FGF60_RS01025 ENOG4105CMQ Chloride channel FGF60_RS01030 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FGF60_RS01035 ENOG4105EN6 Membrane FGF60_RS01040 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FGF60_RS01050 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein FGF60_RS01055 ENOG4105C0H protease FGF60_RS01060 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR FGF60_RS01070 ENOG4105CSH Transporter FGF60_RS01075 ENOG4105DMJ Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity) FGF60_RS01085 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FGF60_RS01090 ENOG4105CE9 30S ribosomal protein S2 FGF60_RS01100 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FGF60_RS01105 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FGF60_RS01120 ENOG4105KNE Phosphatidate cytidylyltransferase FGF60_RS01130 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FGF60_RS01135 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) FGF60_RS01140 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FGF60_RS01145 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) FGF60_RS01155 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FGF60_RS01165 ENOG4105C0B DNA polymerase III (alpha subunit) FGF60_RS01175 ENOG4108RS6 transposase FGF60_RS01185 ENOG4108M1A Chitin-binding protein FGF60_RS01190 ENOG4105CXN decarboxylase FGF60_RS01195 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FGF60_RS01200 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FGF60_RS01205 ENOG4105M1T rho-binding antiterminator FGF60_RS01215 ENOG4108VWS Yaeq family FGF60_RS01220 ENOG4108YZN class I peptide chain release factor FGF60_RS01225 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion FGF60_RS01235 ENOG4108R96 Methyltransferase, YaeB family FGF60_RS01240 ENOG4108R8X outer membrane lipoprotein FGF60_RS01245 ENOG4105D01 (LipO)protein FGF60_RS01250 ENOG4108UMI ABC transporter, permease FGF60_RS01255 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FGF60_RS01260 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FGF60_RS01295 ENOG4105CV8 reductase FGF60_RS01300 ENOG4105HEI LysR family (Transcriptional regulator FGF60_RS01305 ENOG4105F27 Major Facilitator FGF60_RS01315 ENOG4105F2W methyltransferase FGF60_RS01320 ENOG4105E9H Lytic Murein transglycosylase FGF60_RS01325 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FGF60_RS01330 ENOG4105D1A Methyltransferase FGF60_RS01335 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FGF60_RS01340 ENOG4107RZZ dna polymerase iii epsilon subunit FGF60_RS01380 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FGF60_RS01470 ENOG4105CS6 Rhs element vgr protein FGF60_RS01480 ENOG4105CNA YD repeat protein FGF60_RS01500 ENOG4105CNA YD repeat protein FGF60_RS01550 ENOG4105W7K Transcriptional regulator FGF60_RS01560 ENOG4105T40 surface antigen msp4 family protein FGF60_RS01570 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FGF60_RS01575 ENOG4107QPN acyl-Coa dehydrogenase FGF60_RS01585 ENOG4105E7A Glutamine amidotransferase FGF60_RS01590 ENOG4105F7V ErfK ybiS ycfS ynhG family protein FGF60_RS01605 ENOG4108S2Y peptide Chain Release factor FGF60_RS01610 ENOG4105CIN aminoacyl-histidine dipeptidase FGF60_RS01615 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) FGF60_RS01630 ENOG4105FCK Membrane FGF60_RS01640 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) FGF60_RS01650 ENOG4108KU3 Integrase FGF60_RS01690 ENOG4105VIZ double-strand break repair protein FGF60_RS01755 ENOG4105CDU Replicative dna helicase FGF60_RS01775 ENOG4105NY2 NinB protein FGF60_RS01805 ENOG4105RWQ Protein of unknown function (DUF1364) FGF60_RS01850 ENOG4105KUS lysozyme FGF60_RS01855 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FGF60_RS01965 ENOG4105CKK Glycosyl transferase, family 2 FGF60_RS01970 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) FGF60_RS01990 ENOG4105V2F Uncharacterized protein yoac FGF60_RS01995 ENOG4105D94 Major Facilitator Superfamily FGF60_RS02000 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FGF60_RS02005 ENOG4108TFY Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FGF60_RS02010 ENOG4105ERH Fumarylacetoacetate hydrolase FGF60_RS02020 ENOG4105EJC lysr family transcriptional regulator FGF60_RS02045 ENOG4105CW0 outer membrane usher protein FGF60_RS02050 ENOG4108VEV chaperone FGF60_RS02055 ENOG4105X0I Fimbrial FGF60_RS02070 ENOG4107XTP (EAL) domain protein FGF60_RS02085 ENOG4108T1M outer membrane protein x FGF60_RS02105 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FGF60_RS02115 ENOG4105C1P efflux transporter, rnd family, mfp subunit FGF60_RS02135 ENOG4105JHE Major Facilitator Superfamily FGF60_RS02140 ENOG4107QMH DNA methylase FGF60_RS02145 ENOG4105D8D Type III FGF60_RS02155 ENOG4105C4M (Ubiquinol oxidase) subunit I FGF60_RS02160 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FGF60_RS02180 ENOG4105E82 cytochrome subunit of dehydrogenase FGF60_RS02185 ENOG4105TDT uncharacterized protein yahO FGF60_RS02190 ENOG4108JU7 Transcriptional regulator FGF60_RS02195 ENOG4105CR4 methylisocitrate lyase FGF60_RS02200 ENOG4105BZN citrate synthase FGF60_RS02205 ENOG4105DXD 2-methylcitrate dehydratase FGF60_RS02210 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FGF60_RS02215 ENOG4105D52 delta-aminolevulinic acid dehydratase FGF60_RS02220 ENOG4108NSE outer membrane autotransporter barrel FGF60_RS02225 ENOG4108PNB DNA-binding transcriptional regulator FGF60_RS02230 ENOG4107R6D beta-lactam binding protein AmpH FGF60_RS02235 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 FGF60_RS02240 ENOG4107QS8 (LipO)protein FGF60_RS02245 ENOG4105FR5 inner membrane protein YaiY FGF60_RS02250 ENOG4105UNH Membrane FGF60_RS02255 ENOG4105CPF Cell wall formation (By similarity) FGF60_RS02275 ENOG4105VIF phosphate starvation-inducible protein FGF60_RS02280 ENOG4105BZU Histidine kinase FGF60_RS02285 ENOG4105II7 pyrroline-5-carboxylate reductase FGF60_RS02300 ENOG4105SS3 FGF60_RS02305 ENOG4105HBA AroM protein FGF60_RS02320 ENOG4105DKQ ROK family FGF60_RS02325 ENOG4105F27 Major Facilitator FGF60_RS02330 ENOG4105EYH Exonuclease FGF60_RS02335 ENOG4107RH8 nuclease SbcCD subunit D FGF60_RS02340 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FGF60_RS02345 ENOG4105BZU Histidine kinase FGF60_RS02350 ENOG4105CWM branched-chain amino acid transport system II carrier protein FGF60_RS02355 ENOG4105C85 amino acid FGF60_RS02360 ENOG4107R28 alpha amylase, catalytic region FGF60_RS02365 ENOG4105D3R alkyl hydroperoxide reductase FGF60_RS02385 ENOG4105VIE preprotein translocase, subunit YajC FGF60_RS02395 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FGF60_RS02410 ENOG4105N1F Hnh endonuclease FGF60_RS02430 ENOG4105DRB nucleoside-specific channel-forming protein FGF60_RS02435 ENOG4108KIC (LipO)protein FGF60_RS02445 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FGF60_RS02455 ENOG4107YIM Involved in the transcription termination process (By similarity) FGF60_RS02460 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FGF60_RS02465 ENOG4108ZAI phosphatidylglycerophosphatase a FGF60_RS02470 ENOG4105CPC Aldo Keto reductase FGF60_RS02480 ENOG4105CTB Polyprenyl synthetase FGF60_RS02485 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FGF60_RS02490 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) FGF60_RS02495 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component FGF60_RS02500 ENOG4108MP3 ABC transporter, permease FGF60_RS02505 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FGF60_RS02510 ENOG4105CY5 solute-binding protein FGF60_RS02515 ENOG4106S9K Transcriptional regulator FGF60_RS02520 ENOG4107STF Involved in phosphonate degradation (By similarity) FGF60_RS02525 ENOG4108KAZ Involved in phosphonate degradation (By similarity) FGF60_RS02530 ENOG4107S0N DJ-1 family FGF60_RS02535 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FGF60_RS02545 ENOG4107RDB Major Facilitator FGF60_RS02570 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FGF60_RS02575 ENOG4105CCU oxidase (Subunit III) FGF60_RS02580 ENOG4105BZ9 Cytochrome C oxidase, subunit I FGF60_RS02585 ENOG4105E2S oxidase) subunit II FGF60_RS02590 ENOG4105EYM Major Facilitator superfamily FGF60_RS02595 ENOG4105IEY (LipO)protein FGF60_RS02600 ENOG4105M85 Bola protein FGF60_RS02625 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FGF60_RS02630 ENOG4105K70 DNA-binding protein FGF60_RS02635 ENOG4105EIN peptidylprolyl cis-trans isomerase FGF60_RS02640 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FGF60_RS02645 ENOG4108TGP Thioesterase superfamily protein FGF60_RS02655 ENOG4108NFA extracellular solute-binding protein FGF60_RS02670 ENOG4108XM1 transcriptional regulator AsnC family FGF60_RS02675 ENOG4105BZ1 (ABC) transporter FGF60_RS02680 ENOG4105BZ1 (ABC) transporter FGF60_RS02690 ENOG4108YZA Nitrogen regulatory protein pii FGF60_RS02695 ENOG4105BZU Histidine kinase FGF60_RS02700 ENOG4105C29 acyl-CoA thioesterase FGF60_RS02705 ENOG4108MNP Glycoprotein polysaccharide metabolism FGF60_RS02710 ENOG41080UX Methyltransferase FGF60_RS02720 ENOG41066DG (EAL) domain protein FGF60_RS02735 ENOG4105GSJ Inner membrane protein ylaC FGF60_RS02740 ENOG4108UW5 maltose o-acetyltransferase FGF60_RS02750 ENOG4108UKR Biofilm formation regulator YbaJ FGF60_RS02755 ENOG4105BZS acriflavin resistance protein FGF60_RS02760 ENOG4105C1P efflux transporter, rnd family, mfp subunit FGF60_RS02765 ENOG4107XI7 Tetr family transcriptional regulator FGF60_RS02770 ENOG4105EGS Mechanosensitive ion channel FGF60_RS02775 ENOG4105DNE Transposase FGF60_RS02780 ENOG4106428 Protein of unknown function (DUF2496) FGF60_RS02785 ENOG4108URS primosomal replication protein n'' FGF60_RS02790 ENOG4105WD1 Membrane FGF60_RS02800 ENOG4107QMP dna polymerase iii subunits gamma and tau FGF60_RS02815 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FGF60_RS02830 ENOG4105F2M alpha beta hydrolase fold-3 domain protein FGF60_RS02835 ENOG4107RE1 Inosine-guanosine kinase FGF60_RS02840 ENOG4105CKD glutathione-regulated potassium-efflux system protein FGF60_RS02845 ENOG4105EU0 Major facilitator Superfamily FGF60_RS02850 ENOG4105CGH 5'-nucleotidase FGF60_RS02855 ENOG4108Z66 YbaK ebsC protein FGF60_RS02860 ENOG4105MBR gumn family FGF60_RS02870 ENOG4105C59 p-type ATPase FGF60_RS02875 ENOG4108Z6Z Transcriptional regulator FGF60_RS02880 ENOG4105G5H Membrane FGF60_RS02885 ENOG4107QX8 SPFH domain, Band 7 family protein FGF60_RS02890 ENOG41083J0 (ABC) transporter FGF60_RS02895 ENOG4105C4B ABC transporter, permease FGF60_RS02900 ENOG4107QR8 Thioredoxin FGF60_RS02905 ENOG4105E1F short-chain dehydrogenase reductase FGF60_RS02910 ENOG4108UJV acyl-CoA thioesterase i FGF60_RS02915 ENOG4108I0Y (ABC) transporter FGF60_RS02920 ENOG4105CV6 ABC transporter, permease FGF60_RS02930 ENOG4105D01 (LipO)protein FGF60_RS02935 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FGF60_RS02940 ENOG4108UMI ABC transporter, permease FGF60_RS02945 ENOG4105CR7 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity) FGF60_RS02955 ENOG4108Z2U ureidoglycolate hydrolase FGF60_RS02965 ENOG41060W2 glyoxylate carboligase FGF60_RS02970 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FGF60_RS02975 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FGF60_RS02985 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FGF60_RS02995 ENOG4105DTE Xanthine uracil vitamin C permease FGF60_RS03000 ENOG4105BZW Glycerate kinase FGF60_RS03005 ENOG4105S0E allantoin catabolism protein FGF60_RS03010 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FGF60_RS03015 ENOG4105DG4 malate L-lactate dehydrogenase FGF60_RS03020 ENOG4107R1Q Membrane protein FdrA FGF60_RS03025 ENOG4107REC cytoplasmic protein FGF60_RS03030 ENOG4105G5A Protein of unknown function (DUF2877) FGF60_RS03035 ENOG4105C5B carbamate kinase FGF60_RS03040 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FGF60_RS03045 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FGF60_RS03055 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FGF60_RS03075 ENOG4105S2T inner membrane protein YbcI FGF60_RS03080 ENOG4105WQ3 Rna-binding protein FGF60_RS03095 ENOG4108WDE Fimbrial protein FGF60_RS03100 ENOG4105NJT Fimbrial protein FGF60_RS03105 ENOG4108AF8 Chaperone FGF60_RS03110 ENOG4105CW0 outer membrane usher protein FGF60_RS03115 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) FGF60_RS03120 ENOG4108ZI2 Fimbrial protein FGF60_RS03125 ENOG4108Q9V regulatoR FGF60_RS03130 ENOG4106721 fimbriae Y protein FGF60_RS03140 ENOG4106KCD HTH_LUXR FGF60_RS03165 ENOG4105CKK Glycosyl transferase, family 2 FGF60_RS03170 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) FGF60_RS03180 ENOG4105GR3 Histidine kinase FGF60_RS03190 ENOG4108K01 transcriptional regulator FGF60_RS03195 ENOG4107QN2 dihydrolipoyl dehydrogenase FGF60_RS03200 ENOG41066GK UPF0379 protein ykgI FGF60_RS03205 ENOG4108KBJ Inner membrane protein YkgB FGF60_RS03215 ENOG4105C85 amino acid FGF60_RS03220 ENOG4105CUY Mechanosensitive ion channel FGF60_RS03230 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FGF60_RS03235 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine FGF60_RS03245 ENOG4105F3R pts system mannose fructose sorbose family iid FGF60_RS03265 ENOG4108RCM Nitroreductase FGF60_RS03270 ENOG4105MSB protein, conserved in bacteria FGF60_RS03275 ENOG41067SE Tetr family transcriptional regulator FGF60_RS03280 ENOG4105HFT AraC family transcriptional regulator FGF60_RS03285 ENOG4105WQ6 Membrane FGF60_RS03290 ENOG4106KXD ATP-dependent carboxylate-amine ligase (By similarity) FGF60_RS03295 ENOG4108TSE Transferase FGF60_RS03300 ENOG4107RNH Outer membrane receptor FepA FGF60_RS03305 ENOG4105E93 esterase FGF60_RS03310 ENOG41085A6 mbth domain-containing protein FGF60_RS03315 ENOG4105C0W non-ribosomal peptide synthetase FGF60_RS03320 ENOG4108QY5 Ferric enterobactin transport protein FGF60_RS03325 ENOG4105E0A ABC, transporter FGF60_RS03330 ENOG4105TVJ transport system, permease FGF60_RS03335 ENOG4105DQ5 transport system permease protein FGF60_RS03340 ENOG4105E8G Major facilitator Superfamily FGF60_RS03345 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein FGF60_RS03350 ENOG4105E4F Isochorismate synthase FGF60_RS03355 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FGF60_RS03360 ENOG4105WQI isochorismatase FGF60_RS03365 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FGF60_RS03370 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) FGF60_RS03375 ENOG4105D22 carbon starvation protein FGF60_RS03380 ENOG4105VCD cytoplasmic protein FGF60_RS03385 ENOG4107SCQ Iron-containing alcohol dehydrogenase FGF60_RS03390 ENOG4105CHM Aminotransferase FGF60_RS03395 ENOG4105GTN ParB Domain Protein Nuclease FGF60_RS03400 ENOG4105BZV Phosphoadenosine phosphosulfate reductase FGF60_RS03405 ENOG4105DQS Transcriptional regulator FGF60_RS03410 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase FGF60_RS03415 ENOG4105D3R alkyl hydroperoxide reductase FGF60_RS03420 ENOG4108JU3 Alkyl hydroperoxide reductase FGF60_RS03430 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) FGF60_RS03435 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FGF60_RS03445 ENOG4108U51 Universal stress protein FGF60_RS03450 ENOG4105E2A Dehydrogenase FGF60_RS03455 ENOG4105NXH GreA GreB family elongation factor FGF60_RS03460 ENOG4105KTS ribonuclease FGF60_RS03465 ENOG4107QPK )-transporter FGF60_RS03470 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FGF60_RS03475 ENOG4105YGP holo-ACP synthase CitX FGF60_RS03480 ENOG4105CHY citrate lyase, alpha FGF60_RS03485 ENOG4105CI0 Citrate lyase FGF60_RS03490 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) FGF60_RS03495 ENOG4105DUA (citrate (pro-3S)-lyase ligase FGF60_RS03500 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FGF60_RS03505 ENOG4106YYS transcriptional regulatory protein FGF60_RS03510 ENOG4105CEE C4-dicarboxylate transporter FGF60_RS03515 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) FGF60_RS03525 ENOG4107Z6W Protein CrcB homolog FGF60_RS03545 ENOG41064T2 transcriptional regulator, lysR family FGF60_RS03555 ENOG4108Z43 UPF0250 protein FGF60_RS03560 ENOG4105DZ1 carboxypeptidase FGF60_RS03565 ENOG4105K6T rare lipoprotein A FGF60_RS03570 ENOG4105CNI cell division protein FtsW FGF60_RS03575 ENOG4105CJN penicillin-binding protein FGF60_RS03580 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) FGF60_RS03585 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) FGF60_RS03590 ENOG4108TGR phosphatase FGF60_RS03595 ENOG4107QZB decarboxylase FGF60_RS03600 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) FGF60_RS03605 ENOG4105DJF DNA polymerase III, delta' subunit FGF60_RS03610 ENOG4108U2H Rare lipoprotein B FGF60_RS03630 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) FGF60_RS03635 ENOG4108JUB Transcriptional regulator FGF60_RS03640 ENOG4107PAI alpha helical protein FGF60_RS03650 ENOG41069CF Protein of unknown function (DUF1266) FGF60_RS03655 ENOG4105QFC Hsc56 co-chaperone of HscC FGF60_RS03660 ENOG41069CF Protein of unknown function (DUF1266) FGF60_RS03665 ENOG4105QFC Hsc56 co-chaperone of HscC FGF60_RS03670 ENOG4105F7F Chaperone FGF60_RS03680 ENOG4105DU0 nucleoside hydrolase FGF60_RS03685 ENOG4105CDA abc transporter atp-binding protein FGF60_RS03690 ENOG4105DRP amino acid AbC transporter FGF60_RS03695 ENOG4105EAD ABC transporter FGF60_RS03700 ENOG4107RP9 extracellular solute-binding protein, family 3 FGF60_RS03705 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FGF60_RS03710 ENOG4108JU5 Magnesium and cobalt efflux protein FGF60_RS03715 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) FGF60_RS03720 ENOG4105C9A Phoh family FGF60_RS03730 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FGF60_RS03775 ENOG4105CAQ asparagine synthetase FGF60_RS03780 ENOG4105D4U had-superfamily hydrolase, subfamily iia FGF60_RS03785 ENOG4105E2R ROK family FGF60_RS03790 ENOG4105CE4 GlcNAc 6-P deacetylase FGF60_RS03800 ENOG4105CI1 PTS System FGF60_RS03810 ENOG4105J5J Outer membrane porin FGF60_RS03815 ENOG4105GX6 (LipO)protein FGF60_RS03820 ENOG4105CSH Transporter FGF60_RS03825 ENOG41079YP Citrate utilization protein b FGF60_RS03830 ENOG4107EFR Flavocytochrome c FGF60_RS03835 ENOG4106P55 Transcriptional regulator FGF60_RS03840 ENOG41090R7 Ferric uptake FGF60_RS03845 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) FGF60_RS03850 ENOG4105NNH LexA regulated protein FGF60_RS03855 ENOG4105EV9 Alpha Beta Hydrolase FGF60_RS03860 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) FGF60_RS03865 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 FGF60_RS03875 ENOG4105D5Q Arginine ornithine antiporter FGF60_RS03880 ENOG4105CXN decarboxylase FGF60_RS03890 ENOG4105EEX Two component transcriptional regulator (Winged helix family FGF60_RS03895 ENOG4105C08 Histidine kinase FGF60_RS03905 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FGF60_RS03920 ENOG4105XIQ Protein of unknown function (DUF2517) FGF60_RS03925 ENOG4105CVP deoxyribo-dipyrimidine photolyase FGF60_RS03935 ENOG4107QNR UPF0135 protein FGF60_RS03940 ENOG4105P4J Allophanate hydrolase, subunit 1 FGF60_RS03945 ENOG4107R7A Allophanate hydrolase subunit 2 FGF60_RS03950 ENOG4105E7W lamb ycsf family protein FGF60_RS03960 ENOG4108W9T type 1 fimbriae regulatory protein FGF60_RS04000 ENOG410602S Transferase FGF60_RS04030 ENOG4108KK1 membrane protein AbrB duplication FGF60_RS04035 ENOG4105BZN citrate synthase FGF60_RS04040 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FGF60_RS04045 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FGF60_RS04050 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FGF60_RS04055 ENOG4105E33 succinate dehydrogenase FGF60_RS04060 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FGF60_RS04065 ENOG4105C7S Dehydrogenase FGF60_RS04075 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FGF60_RS04080 ENOG4105C4M (Ubiquinol oxidase) subunit I FGF60_RS04085 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FGF60_RS04095 ENOG4105KJB cyd operon protein YbgE FGF60_RS04100 ENOG4107YD3 Thioesterase FGF60_RS04105 ENOG4105E02 MotA TolQ exbB proton channel FGF60_RS04115 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA FGF60_RS04125 ENOG4105KCK Peptidoglycan-associated lipoprotein FGF60_RS04130 ENOG4105UFD tol-pal system protein YbgF FGF60_RS04175 ENOG4106Z1T Nicotinamide Mononucleotide Transporter FGF60_RS04180 ENOG4105PGM cation diffusion facilitator family transporter FGF60_RS04185 ENOG4105JND homeobox protein FGF60_RS04190 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FGF60_RS04195 ENOG4107GFK fumarate FGF60_RS04200 ENOG4106DSS Tartrate dehydratase subunit alpha FGF60_RS04205 ENOG4105C5Q Transcriptional regulator FGF60_RS04215 ENOG4107QWE )-transporter FGF60_RS04220 ENOG4106AFN Lyase and sodium transporter (By similarity) FGF60_RS04225 ENOG4107QSA Oxaloacetate decarboxylase FGF60_RS04230 ENOG4105D9Q decarboxylase (Beta subunit) FGF60_RS04235 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FGF60_RS04240 ENOG4105EHG Permease protein FGF60_RS04245 ENOG4105E0A ABC, transporter FGF60_RS04255 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FGF60_RS04265 ENOG4105F0Z galactose-1-phosphate uridylyltransferase FGF60_RS04270 ENOG4105CMR udp-glucose 4-epimerase FGF60_RS04280 ENOG4105DKW ABC transporter FGF60_RS04285 ENOG4105F4R Transcriptional regulator mode FGF60_RS04295 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FGF60_RS04300 ENOG4105E0C molybdate abc transporter FGF60_RS04310 ENOG4108K4B hydrolase FGF60_RS04320 ENOG4105NBR Pectinesterase FGF60_RS04325 ENOG4105CI2 imidazolone-5-propionate hydrolase FGF60_RS04345 ENOG4105C84 Histidine ammonia-lyase FGF60_RS04350 ENOG4108V1U phospholipid-binding protein FGF60_RS04355 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FGF60_RS04365 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FGF60_RS04370 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FGF60_RS04375 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FGF60_RS04400 ENOG4105CHW UPF0052 protein FGF60_RS04410 ENOG4108RIR Molybdenum cofactor biosynthesis protein FGF60_RS04420 ENOG4105M00 molybdopterin converting factor, subunit 1 FGF60_RS04425 ENOG4108ZAF Molybdopterin FGF60_RS04430 ENOG4105HFZ Membrane FGF60_RS04450 ENOG4107UXM Membrane FGF60_RS04455 ENOG4105DZQ phospholipase D Transphosphatidylase FGF60_RS04460 ENOG4105X23 Endonuclease Exonuclease phosphatase FGF60_RS04465 ENOG4105I9U inner membrane protein ybhQ FGF60_RS04470 ENOG4107QWP ABC-2 type transporter FGF60_RS04475 ENOG4107QWP ABC-2 type transporter FGF60_RS04480 ENOG4105CJ1 ABC, transporter FGF60_RS04490 ENOG4107MVR Transcriptional regulator FGF60_RS04495 ENOG4105C1J atp-dependent rna helicase FGF60_RS04500 ENOG4105DVT helicase FGF60_RS04505 ENOG4108MTB glycosyl transferase family FGF60_RS04510 ENOG4105VR4 UPF0379 protein ybiJ FGF60_RS04515 ENOG4105KSC Transcriptional regulator, TraR DksA family FGF60_RS04525 ENOG4105D8X mechanosensitive ion channel FGF60_RS04530 ENOG4105CDA abc transporter atp-binding protein FGF60_RS04535 ENOG4105E5Q amino acid AbC transporter FGF60_RS04540 ENOG4107R0W ABC transporter FGF60_RS04555 ENOG4108T1M outer membrane protein x FGF60_RS04560 ENOG4108I6E Sulfatase FGF60_RS04570 ENOG4105KST dependent repressor FGF60_RS04575 ENOG4105F4P )-transporter FGF60_RS04580 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FGF60_RS04585 ENOG4105C5H ABC transporter FGF60_RS04600 ENOG41072TH Protein of unknown function (DUF1479) FGF60_RS04605 ENOG4108HCJ Hydrolase FGF60_RS04615 ENOG4105F1A Pyruvate formate-lyase FGF60_RS04620 ENOG4105D06 uba thif-type nad fad binding protein FGF60_RS04625 ENOG4105CVM Molybdenum cofactor synthesis domain protein FGF60_RS04630 ENOG4105D44 asparaginase FGF60_RS04635 ENOG4108JQ6 ABC transporter FGF60_RS04640 ENOG4105DEF Extracellular solute-binding protein, family 5 FGF60_RS04645 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FGF60_RS04660 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway FGF60_RS04665 ENOG4105CI0 Citrate lyase FGF60_RS04670 ENOG4105BZJ Electron transfer flavoprotein FGF60_RS04675 ENOG4105C10 Electron transfer flavoprotein FGF60_RS04685 ENOG4105C1G acyl-Coa dehydrogenase FGF60_RS04690 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FGF60_RS04695 ENOG4108KB2 LysR family Transcriptional regulator FGF60_RS04700 ENOG4105CY2 Citrate transporter FGF60_RS04705 ENOG4105D8V Glucose sorbosone dehydrogenase FGF60_RS04710 ENOG4108TGY Glutathione S-transferase FGF60_RS04715 ENOG4105DZ1 carboxypeptidase FGF60_RS04720 ENOG4107FB0 transcriptional regulator DeoR family FGF60_RS04725 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FGF60_RS04730 ENOG4107QF7 multi-drug FGF60_RS04735 ENOG4108HCJ Hydrolase FGF60_RS04740 ENOG4106UW1 Major Facilitator superfamily FGF60_RS04745 ENOG4108RFG Tetr family transcriptional regulator FGF60_RS04760 ENOG4105GWF inner membrane protein YbjM FGF60_RS04765 ENOG41090BQ Glutaredoxin FGF60_RS04770 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress FGF60_RS04775 ENOG4108DBC nitroreductase FGF60_RS04785 ENOG4108RMJ sensory transduction regulator FGF60_RS04790 ENOG4107RUE extracellular solute-binding protein family 1 FGF60_RS04795 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FGF60_RS04800 ENOG4105F38 ABC transporter, permease FGF60_RS04805 ENOG4105D38 putrescine abc transporter FGF60_RS04810 ENOG4105RBQ inner membrane protein ybjO FGF60_RS04815 ENOG4107SFS Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity) FGF60_RS04835 ENOG4106TNF Periplasmic binding protein FGF60_RS04840 ENOG4105DMR ABC, transporter FGF60_RS04845 ENOG4105GBT ABC transporter FGF60_RS04850 ENOG4106PMH Extracellular solute-binding protein family 3 FGF60_RS04855 ENOG4105E5Z arginine transporter ATP-binding subunit FGF60_RS04860 ENOG41064MM (LipO)protein FGF60_RS04870 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FGF60_RS04875 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FGF60_RS04880 ENOG4105CGD Nad-dependent epimerase dehydratase FGF60_RS04885 ENOG4105C5W Aldolase FGF60_RS04890 ENOG4105C7K acetolactate synthase FGF60_RS04895 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FGF60_RS04900 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FGF60_RS04905 ENOG4105DWU Membrane FGF60_RS04910 ENOG4105CPB ATP-dependent endonuclease of the OLD family FGF60_RS04915 ENOG4108MJ5 VirK protein FGF60_RS04920 ENOG4105DJY efflux transporter, rnd family, mfp subunit FGF60_RS04925 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FGF60_RS04930 ENOG4105VEQ Cold shock protein FGF60_RS04940 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FGF60_RS04945 ENOG4108RS6 transposase FGF60_RS04965 ENOG4105CHJ isochorismatase hydrolase FGF60_RS04970 ENOG4105EUB pirin domain protein FGF60_RS04975 ENOG4105HEI LysR family (Transcriptional regulator FGF60_RS04980 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FGF60_RS04995 ENOG4108JJ8 (ABC) transporter FGF60_RS05000 ENOG4108JJ9 ABC, transporter FGF60_RS05005 ENOG4105C3M thioredoxin reductase FGF60_RS05010 ENOG4105EW9 transcriptional regulator AsnC family FGF60_RS05015 ENOG4105CNU cell division protein FtsK FGF60_RS05025 ENOG4105D1H recombination factor protein RarA FGF60_RS05035 ENOG4107QY8 reductase FGF60_RS05040 ENOG4105QAX Iron-sulfur FGF60_RS05045 ENOG4107KGK dmso reductase anchor subunit FGF60_RS05055 ENOG4105E5D amino acid FGF60_RS05060 ENOG4105F1A Pyruvate formate-lyase FGF60_RS05070 ENOG4105GUS FGF60_RS05075 ENOG4105C6N Formate acetyltransferase FGF60_RS05080 ENOG4105TMB Formate nitrite transporter FGF60_RS05085 ENOG4105DDY UPF0142 protein ycaO FGF60_RS05090 ENOG4107VMU Membrane FGF60_RS05100 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FGF60_RS05105 ENOG4108K0D peptidase, M48 FGF60_RS05110 ENOG4105CAT Cytidine monophosphate kinase FGF60_RS05115 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FGF60_RS05120 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) FGF60_RS05125 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 FGF60_RS05130 ENOG4105BZ1 (ABC) transporter FGF60_RS05140 ENOG4105T0Z Conserved Protein FGF60_RS05155 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups FGF60_RS05160 ENOG4107S90 membrAne FGF60_RS05165 ENOG4106371 Methyltransferase FGF60_RS05175 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) FGF60_RS05180 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) FGF60_RS05185 ENOG4105DIT ErfK YbiS YcfS YnhG family protein FGF60_RS05190 ENOG4105EAQ (twin-arginine translocation) pathway signal FGF60_RS05195 ENOG4105C5X domain protein FGF60_RS05200 ENOG4105CGF Aromatic amino acid aminotransferase FGF60_RS05205 ENOG4105FCK Membrane FGF60_RS05210 ENOG4105C5S asparaginyl-tRNA synthetase FGF60_RS05225 ENOG4107RCH Diaminopropionate ammonia-lyase FGF60_RS05235 ENOG4107RH7 Nicotinate phosphoribosyltransferase FGF60_RS05240 ENOG4107R08 Integrase FGF60_RS05300 ENOG4105JBR DNA replication protein FGF60_RS05320 ENOG4105MEA DNA damage-inducible protein i FGF60_RS05350 ENOG4105HGD Antitermination protein FGF60_RS05385 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FGF60_RS05460 ENOG4108T1M outer membrane protein x FGF60_RS05500 ENOG4108X9F tail fiber protein FGF60_RS05505 ENOG4105UZW Tail fiber assembly protein FGF60_RS05515 ENOG4106EE1 FGF60_RS05525 ENOG4108RAV Conserved protein FGF60_RS05540 ENOG4105Y50 Virulence Protein FGF60_RS05545 ENOG4105CD8 aminopeptidase N FGF60_RS05555 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) FGF60_RS05560 ENOG4105QVC MOSC domain-containing protein FGF60_RS05570 ENOG4105C5H ABC transporter FGF60_RS05575 ENOG4105F1S paraquat-inducible protein a FGF60_RS05580 ENOG4105DY2 Paraquat-inducible protein b FGF60_RS05585 ENOG4108Q2G (LipO)protein FGF60_RS05590 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) FGF60_RS05600 ENOG4105DAN ATP-dependent protease FGF60_RS05610 ENOG4105UYK outer membrane protein a FGF60_RS05620 ENOG4108RZ1 DNA transformation protein FGF60_RS05625 ENOG4105EM2 membrane FGF60_RS05630 ENOG410901E Membrane FGF60_RS05635 ENOG41088T4 Helicase IV FGF60_RS05640 ENOG4108Z5K methylglyoxal synthase FGF60_RS05650 ENOG4105K4P CoA-binding domain protein FGF60_RS05665 ENOG4108V1U phospholipid-binding protein FGF60_RS05675 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FGF60_RS05685 ENOG4108MN8 Membrane FGF60_RS05700 ENOG41084BJ Pentapeptide repeat protein FGF60_RS05710 ENOG4106HNN Invasion protein FGF60_RS05715 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell FGF60_RS05720 ENOG4106YSC FGF60_RS05735 ENOG4107ZY3 Histidine kinase FGF60_RS05740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FGF60_RS05745 ENOG4105VT2 5-hydroxyisourate hydrolase FGF60_RS05750 ENOG4107UWN reductase FGF60_RS05755 ENOG4105EFA 4-hydroxyphenylacetate FGF60_RS05760 ENOG4108V8F Transcriptional regulator, MarR family FGF60_RS05770 ENOG4105C26 Dehydrogenase FGF60_RS05775 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase FGF60_RS05790 ENOG4105CNV Aldolase FGF60_RS05830 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FGF60_RS05835 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FGF60_RS05840 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FGF60_RS05845 ENOG4105D6F Phosphatase FGF60_RS05850 ENOG4105XH3 FGF60_RS05860 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 FGF60_RS05865 ENOG4108R86 Transcriptional regulator FGF60_RS05880 ENOG4105CK7 Sodium proline symporter FGF60_RS05885 ENOG4105D5M phosphate starvation-inducible protein FGF60_RS05890 ENOG4105QEK Transcriptional regulator FGF60_RS05895 ENOG4107RJ1 sodium solute FGF60_RS05900 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) FGF60_RS05905 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) FGF60_RS05910 ENOG4108QGT oligogalacturonate-specific porin FGF60_RS05915 ENOG4105JHE Major Facilitator Superfamily FGF60_RS05920 ENOG4107RJ5 oxidoreductase FGF60_RS05960 ENOG4107XHZ cytoplasmic chaperone TorD family protein FGF60_RS05965 ENOG4108UQ5 membrane protein YcdZ FGF60_RS05970 ENOG4105P8Q Curli production assembly transport component CsgG FGF60_RS05975 ENOG4108WYR Curli production assembly transport component, CsgF FGF60_RS05980 ENOG4108XDW curli assembly protein CsgE FGF60_RS05985 ENOG41086KC Transcriptional regulator FGF60_RS05990 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers FGF60_RS05995 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin FGF60_RS06000 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) FGF60_RS06005 ENOG41068SS FGF60_RS06010 ENOG4108UVJ appr-1-p processing domain protein FGF60_RS06015 ENOG4107RZC phospholipase d FGF60_RS06020 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) FGF60_RS06030 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) FGF60_RS06035 ENOG4105NAC (LipO)protein FGF60_RS06040 ENOG4108W47 Acidic protein msyB FGF60_RS06045 ENOG4105C6X Major Facilitator FGF60_RS06050 ENOG4105D1S lipid A biosynthesis FGF60_RS06055 ENOG4105C72 UPF0176 protein FGF60_RS06060 ENOG4108YYC ycei family FGF60_RS06065 ENOG4105DS1 cytochrome b561 FGF60_RS06070 ENOG4106974 biofilm formation FGF60_RS06075 ENOG4105F76 Sarcosine oxidase FGF60_RS06080 ENOG4105PVA Biofilm formation regulatory protein BssS FGF60_RS06085 ENOG4105MEA DNA damage-inducible protein i FGF60_RS06090 ENOG4105EKE dihydroorotase FGF60_RS06095 ENOG4105F3T (LipO)protein FGF60_RS06100 ENOG4105E9S glutaredoxin 2 FGF60_RS06110 ENOG4105D9U N-acetyltransferase FGF60_RS06120 ENOG4105EP9 oxidoreductase FGF60_RS06125 ENOG4105CJR Integral membrane protein (MviN FGF60_RS06130 ENOG4105QVD Flagella synthesis protein FlgN FGF60_RS06135 ENOG4105M9M anti-sigma28 factor FlgM FGF60_RS06140 ENOG4105CKS Flagella basal body P-ring formation protein flgA FGF60_RS06145 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FGF60_RS06150 ENOG4108ZC9 flagellar basal-body rod protein flgc FGF60_RS06155 ENOG4105W00 Flagellar hook capping protein FGF60_RS06160 ENOG4105BZE flagellar hook protein, FlgE FGF60_RS06165 ENOG4108KPB Flagellar basal-body rod protein FlgF FGF60_RS06170 ENOG4105CGA flagellar basal-body rod protein FlgG FGF60_RS06185 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FGF60_RS06190 ENOG4105E1Q flagellar hook-associated protein FGF60_RS06195 ENOG4105DTJ flagellar hook-associated protein FGF60_RS06200 ENOG4107QQB Ribonuclease E FGF60_RS06205 ENOG4105EI2 Pseudouridine synthase FGF60_RS06220 ENOG4108UHJ MAF-like protein FGF60_RS06225 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FGF60_RS06240 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FGF60_RS06245 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FGF60_RS06250 ENOG4105CHR reductase FGF60_RS06255 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FGF60_RS06260 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FGF60_RS06265 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FGF60_RS06270 ENOG4105HHA aminodeoxychorismate lyase FGF60_RS06280 ENOG4107QRG dna polymerase iii FGF60_RS06285 ENOG4105F8V Hydrolase, tatD family FGF60_RS06290 ENOG4105CI1 PTS System FGF60_RS06295 ENOG4105CNM Receptor FGF60_RS06300 ENOG4105K59 histidine triad (HIT) protein FGF60_RS06305 ENOG41090DQ Lipoprotein FGF60_RS06310 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) FGF60_RS06315 ENOG4108RUM thiamine kinase FGF60_RS06330 ENOG4105CEP NADH dehydrogenase FGF60_RS06335 ENOG4107MBR 17 kDa surface antigen FGF60_RS06340 ENOG4108IND Tetr family transcriptional regulator FGF60_RS06345 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction FGF60_RS06350 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FGF60_RS06355 ENOG4108JA2 transcriptioN-repair coupling factor FGF60_RS06360 ENOG4105D60 lipoprotein releasing system transmembrane protein FGF60_RS06365 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FGF60_RS06370 ENOG4105D60 lipoprotein releasing system transmembrane protein FGF60_RS06380 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FGF60_RS06385 ENOG4108HM4 ABC transporter FGF60_RS06390 ENOG4105D38 putrescine abc transporter FGF60_RS06405 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FGF60_RS06420 ENOG4105EZE Cupin 4 family protein FGF60_RS06435 ENOG4107QTF adenylosuccinate lyase FGF60_RS06445 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FGF60_RS06460 ENOG4108R99 pseudouridine synthase FGF60_RS06465 ENOG4108HMX isocitrate dehydrogenase (NADP) FGF60_RS06470 ENOG4108RS6 transposase FGF60_RS06495 ENOG4105Y50 Virulence Protein FGF60_RS06500 ENOG4106F2Y RICIN FGF60_RS06505 ENOG41060EU Cold shock-like protein FGF60_RS06520 ENOG4105H38 Membrane FGF60_RS06545 ENOG4108ZNX Heat shock protein FGF60_RS06555 ENOG4108VKM cytochrome b561 FGF60_RS06570 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FGF60_RS06580 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) FGF60_RS06585 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) FGF60_RS06590 ENOG4105D64 Mechanosensitive ion channel FGF60_RS06605 ENOG4108MEK Metal-binding protein YodA FGF60_RS06620 ENOG4108Z6Z Transcriptional regulator FGF60_RS06635 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) FGF60_RS06645 ENOG4108YS1 cytoplasmic protein FGF60_RS06650 ENOG4105YP6 Domain of unknown function (DUF1869) FGF60_RS06665 ENOG4105Y3U Transglycosylase-associated protein FGF60_RS06670 ENOG4106G4W FGF60_RS06675 ENOG4105UCG Domain of unknown function (DUF333) FGF60_RS06685 ENOG4105K78 MarR family Transcriptional regulator FGF60_RS06690 ENOG4105DJ2 Major Facilitator Superfamily FGF60_RS06695 ENOG4105R1U AraC Family Transcriptional Regulator FGF60_RS06710 ENOG4108KXH Ybak prolyl-tRNA synthetase associated FGF60_RS06715 ENOG4108KHP Diguanylate cyclase FGF60_RS06725 ENOG4105CYN Serine protein kinase FGF60_RS06730 ENOG4105GNX MltA-interacting MipA family protein FGF60_RS06735 ENOG4105C4X radical SAM domain protein FGF60_RS06740 ENOG4105CV8 reductase FGF60_RS06745 ENOG4105DSB aldose 1-epimerase FGF60_RS06750 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FGF60_RS06760 ENOG4105VUT cytoplasmic protein FGF60_RS06765 ENOG4108RWI nicotinamidase FGF60_RS06770 ENOG4105HDK L-asparaginase FGF60_RS06775 ENOG4105D07 Signal peptide peptidase, SppA FGF60_RS06780 ENOG41069NU Nitroreductase FGF60_RS06785 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) FGF60_RS06790 ENOG4108IYH Dna topoisomerase FGF60_RS06795 ENOG4105D82 Glutamate dehydrogenase FGF60_RS06800 ENOG4105MTM Protein of unknown function (DUF1496) FGF60_RS06805 ENOG4105M6F mutator MutT protein FGF60_RS06810 ENOG4105CGK Exodeoxyribonuclease III FGF60_RS06815 ENOG4105C8Y Acetylornithine aminotransferase FGF60_RS06825 ENOG4105C26 Dehydrogenase FGF60_RS06835 ENOG4107UI5 Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity) FGF60_RS06840 ENOG4108SPG Periplasmic Protein FGF60_RS06845 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) FGF60_RS06855 ENOG4105KKI DNA-binding transcriptional activator OsmE FGF60_RS06860 ENOG4105VZJ PTS System FGF60_RS06865 ENOG4105CK1 PTS System FGF60_RS06870 ENOG4105VCP PTS System FGF60_RS06875 ENOG4105EZV Transcriptional regulator FGF60_RS06880 ENOG4105F8D glycoside hydrolase family 4 FGF60_RS06885 ENOG410901P UPF0249 protein FGF60_RS06890 ENOG4105CH6 catalase FGF60_RS06900 ENOG4108ETY sodium dicarboxylate symporter FGF60_RS06905 ENOG4107K5X Membrane-bound metal-dependent hydrolase FGF60_RS06910 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 FGF60_RS06915 ENOG4107PN8 YfeABCD locus regulator FGF60_RS06925 ENOG4105P10 Uncharacterized protein ydiZ FGF60_RS06930 ENOG4105DE4 1-phosphofructokinase FGF60_RS06935 ENOG4108NE3 Salt-induced outer membrane protein FGF60_RS06960 ENOG4105K25 O-Antigen polymerase FGF60_RS06975 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FGF60_RS06980 ENOG41082NX 50s ribosomal protein l35 FGF60_RS07000 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FGF60_RS07005 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) FGF60_RS07015 ENOG4108V06 Glutathione peroxidase FGF60_RS07025 ENOG4108QBX (LipO)protein FGF60_RS07035 ENOG4105CNG UPF0061 protein FGF60_RS07045 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FGF60_RS07055 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FGF60_RS07060 ENOG4105CEY Amp-dependent synthetase and ligase FGF60_RS07065 ENOG41090P5 ferredoxin-like protein FGF60_RS07070 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FGF60_RS07075 ENOG4105C10 Electron transfer flavoprotein FGF60_RS07080 ENOG4105CV7 Electron transfer flavoprotein FGF60_RS07085 ENOG4105W4W Transcriptional regulator FGF60_RS07090 ENOG4105C1G acyl-Coa dehydrogenase FGF60_RS07095 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FGF60_RS07100 ENOG4105FF2 Type I DHQase FGF60_RS07105 ENOG4105E2X shikimate dehydrogenase FGF60_RS07110 ENOG4105EMV Major Facilitator FGF60_RS07115 ENOG4105EMV Major Facilitator FGF60_RS07120 ENOG4105SUA Ydil protein FGF60_RS07130 ENOG4105IPI Membrane FGF60_RS07135 ENOG4105CQB FAD linked oxidase domain protein FGF60_RS07140 ENOG4105KA0 thioesterase Superfamily protein FGF60_RS07145 ENOG410671Z uncharacterized protein ydiH FGF60_RS07150 ENOG4108ETY sodium dicarboxylate symporter FGF60_RS07155 ENOG4108Z4V iron-sulfur cluster assembly FGF60_RS07160 ENOG4105DIW FeS assembly protein SUFB FGF60_RS07165 ENOG4105C3K feS assembly ATPase SufC FGF60_RS07170 ENOG4105JRK feS assembly protein SufD FGF60_RS07185 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FGF60_RS07200 ENOG4105CA9 Pyruvate kinase FGF60_RS07205 ENOG4105CUB amino acid FGF60_RS07210 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) FGF60_RS07220 ENOG4108RVA ribokinase FGF60_RS07225 ENOG4105DB1 molybdopterin oxidoreductase FGF60_RS07230 ENOG4106WHD Tetrathionate reductase FGF60_RS07235 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FGF60_RS07240 ENOG4106AFQ Histidine kinase FGF60_RS07245 ENOG4108ZXC Two component transcriptional regulator, luxr family FGF60_RS07250 ENOG4105RFR Protein of unknown function (DUF2767) FGF60_RS07255 ENOG4107SEY Conserved Protein FGF60_RS07260 ENOG4108XDN Transcriptional regulator FGF60_RS07270 ENOG4105BZU Histidine kinase FGF60_RS07300 ENOG4105ZQI secreted protein FGF60_RS07310 ENOG4108SZ7 secretion system effector FGF60_RS07315 ENOG4106FZW pathogenicity island effector protein FGF60_RS07365 ENOG4106563 type III secretion system apparatus protein FGF60_RS07370 ENOG4105UQF type iii secretion FGF60_RS07375 ENOG4106H1D secretion system apparatus protein FGF60_RS07385 ENOG4108JIR Flagellum-specific ATP synthase FGF60_RS07400 ENOG41063Q7 Type III secretion system protein FGF60_RS07405 ENOG4108HHI Type III secretion system protein FGF60_RS07410 ENOG41083GP type iii secretion FGF60_RS07415 ENOG4108TN6 type iii secretion FGF60_RS07420 ENOG4108IUF type iii secretion FGF60_RS07440 ENOG4108R6K riboflavin synthase, subunit alpha FGF60_RS07445 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FGF60_RS07450 ENOG4105CZQ inner membrane transport protein YdhC FGF60_RS07455 ENOG4105F52 Transcriptional regulator FGF60_RS07470 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FGF60_RS07475 ENOG4105K4H Nlp p60 protein FGF60_RS07480 ENOG4105M2J Glutaredoxin FGF60_RS07490 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) FGF60_RS07495 ENOG4108UYE Lactoylglutathione lyase FGF60_RS07500 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FGF60_RS07505 ENOG4108WUH Transcriptional regulator, TetR family FGF60_RS07510 ENOG4105XZD Fe-S protein FGF60_RS07515 ENOG4107RGM aldo keto reductase FGF60_RS07520 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FGF60_RS07525 ENOG4105DSW Fusaric acid resistance protein FGF60_RS07530 ENOG4105Y49 secretion protein, HlyD family FGF60_RS07545 ENOG4108XTF Outer Membrane Lipoprotein FGF60_RS07555 ENOG410642K Lysozyme inhibitor FGF60_RS07575 ENOG4108K3A Glutathione S-transferase FGF60_RS07580 ENOG4105DUX Transporter FGF60_RS07585 ENOG4105CSM endonuclease III FGF60_RS07595 ENOG4108UQQ Electron transport complex FGF60_RS07605 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) FGF60_RS07620 ENOG4105M9B inner membrane protein ydgK FGF60_RS07630 ENOG4106C6R beta-lactam resistance protein FGF60_RS07635 ENOG4105D9R oxidoreductase FGF60_RS07640 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FGF60_RS07650 ENOG4105CI1 PTS System FGF60_RS07655 ENOG4106J39 exported protein FGF60_RS07660 ENOG4105EIP mannose-6-phosphate isomerase FGF60_RS07665 ENOG4107GFK fumarate FGF60_RS07670 ENOG4105C9Q fumarate hydratase class II FGF60_RS07680 ENOG4105JJR Histidine kinase FGF60_RS07685 ENOG4105CPN adenine deaminase FGF60_RS07690 ENOG4105FCK Membrane FGF60_RS07700 ENOG4107EXC regulatoR FGF60_RS07705 ENOG4105RA2 Membrane FGF60_RS07710 ENOG4105D5Q Arginine ornithine antiporter FGF60_RS07715 ENOG4105C5D exported protein FGF60_RS07720 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FGF60_RS07725 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FGF60_RS07730 ENOG4105DSF transport protein FGF60_RS07750 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap FGF60_RS07760 ENOG4105D94 Major Facilitator Superfamily FGF60_RS07765 ENOG4106NZI LysR family Transcriptional regulator FGF60_RS07770 ENOG4105DAG ROK family FGF60_RS07775 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FGF60_RS07780 ENOG4105CMQ Chloride channel FGF60_RS07785 ENOG4108IJ8 ABC transporter FGF60_RS07790 ENOG4105E90 ABC transporter FGF60_RS07795 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system FGF60_RS07800 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component FGF60_RS07805 ENOG4108NEM leader-binding protein dmsD FGF60_RS07810 ENOG4107KGK dmso reductase anchor subunit FGF60_RS07815 ENOG4105QAX Iron-sulfur FGF60_RS07820 ENOG4105C3J Cysteine desulfurase FGF60_RS07825 ENOG4107QY8 reductase FGF60_RS07830 ENOG4105KBG Protein of unknown function (DUF1161) FGF60_RS07840 ENOG4108MK9 spermidine N(1)-acetyltransferase FGF60_RS07860 ENOG4105CPQ Dehydrogenase FGF60_RS07875 ENOG4105DEI Mannitol dehydrogenase FGF60_RS07880 ENOG41061EV selenium-binding protein YdfZ FGF60_RS07885 ENOG4107XBN GntR Family Transcriptional Regulator FGF60_RS07890 ENOG4105EMU Dehydrogenase FGF60_RS07895 ENOG4105DGW oligopeptidase A FGF60_RS07915 ENOG4108WTK competence damage-inducible protein FGF60_RS07920 ENOG4108YDI single-species biofilm formation on inanimate substrate FGF60_RS07930 ENOG4105E5W Transporter FGF60_RS07935 ENOG4108594 Permease of the drug metabolite transporter FGF60_RS07940 ENOG4106DNR multiple antibiotic resistance protein FGF60_RS07945 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF FGF60_RS07950 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FGF60_RS07960 ENOG4105F27 Major Facilitator FGF60_RS07965 ENOG4105EGI Transcriptional regulator FGF60_RS07970 ENOG4105C26 Dehydrogenase FGF60_RS07980 ENOG4105M0C cytoplasmic protein FGF60_RS07985 ENOG4105FFC UPF0187 protein FGF60_RS08010 ENOG4105MVP hydrogenase-1 operon protein HyaF FGF60_RS08030 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit FGF60_RS08035 ENOG4105DPX Hydrogenase, large subunit FGF60_RS08050 ENOG4105C6F GntR Family Transcriptional Regulator FGF60_RS08055 ENOG4105CPQ Dehydrogenase FGF60_RS08060 ENOG4108I5G Major Facilitator superfamily FGF60_RS08085 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) FGF60_RS08090 ENOG4108UQ8 endoribonuclease L-psp FGF60_RS08140 ENOG41060NJ transcriptional regulator FGF60_RS08145 ENOG4105DFD Na H antiporter FGF60_RS08150 ENOG4105C87 Aminotransferase class I and II FGF60_RS08165 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) FGF60_RS08175 ENOG4105XXV Acid-resistance protein FGF60_RS08180 ENOG4108Z9K Osmotically inducible protein FGF60_RS08185 ENOG4105TPS biofilm-dependent modulation protein FGF60_RS08200 ENOG4105DQ4 alcohol dehydrogenase FGF60_RS08205 ENOG4108MG3 formate dehydrogenase FGF60_RS08210 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FGF60_RS08245 ENOG4107QND Nitrite extrusion protein FGF60_RS08250 ENOG4105CRU nitrate reductase, alpha subunit FGF60_RS08255 ENOG4108IUE nitrate reductase beta subunit FGF60_RS08260 ENOG4108NZN Respiratory nitrate reductase 2 delta chain FGF60_RS08265 ENOG4105D0D Nitrate reductase 2, gamma subunit FGF60_RS08275 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FGF60_RS08290 ENOG4105C85 amino acid FGF60_RS08295 ENOG4105SUV lipoprotein YgdR FGF60_RS08300 ENOG4108NS2 receptor FGF60_RS08305 ENOG4105CHB tonB-dependent Receptor FGF60_RS08310 ENOG4108WYP Transcriptional regulator FGF60_RS08315 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FGF60_RS08320 ENOG4108Z7F N-acetyltransferase FGF60_RS08325 ENOG4108T9Y Inner membrane protein ydcZ FGF60_RS08330 ENOG4105R71 cytoplasmic protein FGF60_RS08350 ENOG410654E Membrane FGF60_RS08360 ENOG4105C26 Dehydrogenase FGF60_RS08365 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FGF60_RS08370 ENOG4108UQS dipeptidase FGF60_RS08390 ENOG4105RR0 Protein of unknown function (DUF2554) FGF60_RS08395 ENOG4105CFP Peptidase U32 FGF60_RS08400 ENOG4108JCI Transcriptional regulator FGF60_RS08405 ENOG4105DKK Benzoate FGF60_RS08410 ENOG4108KKZ (LipO)protein FGF60_RS08415 ENOG41088CC tellurite resistance protein tehB FGF60_RS08420 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein FGF60_RS08425 ENOG4107WE3 acetyltransferase YdcK FGF60_RS08430 ENOG4108Z9I -acetyltransferase FGF60_RS08435 ENOG4105CN9 Peptidase m42 family protein FGF60_RS08440 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) FGF60_RS08445 ENOG4105DT3 PTS system, galactitol-specific IIc component FGF60_RS08450 ENOG4106P19 photosystem i assembly btpa FGF60_RS08455 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) FGF60_RS08460 ENOG4108RK0 3-epimerase FGF60_RS08465 ENOG4108PQ7 sgc region transcriptional regulator FGF60_RS08470 ENOG4105M4B Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity) FGF60_RS08480 ENOG4108YYC ycei family FGF60_RS08485 ENOG4105DJ9 glucan biosynthesis protein FGF60_RS08490 ENOG4105EBR Carboxylesterase FGF60_RS08495 ENOG4105E32 cytoplasmic protein FGF60_RS08500 ENOG4105DDW LysR family Transcriptional regulator FGF60_RS08505 ENOG4105C8Q Methyl-accepting chemotaxis FGF60_RS08530 ENOG4107ZUJ lipid metabolic process FGF60_RS08540 ENOG4107R0W ABC transporter FGF60_RS08545 ENOG4105E5Q amino acid AbC transporter FGF60_RS08555 ENOG4105E5Q amino acid AbC transporter FGF60_RS08565 ENOG4108WF3 methyltransferase FGF60_RS08570 ENOG4105CPW cytochrome b561 FGF60_RS08575 ENOG4107DB1 DUF218 domain FGF60_RS08580 ENOG4105CQ7 ATP-dependent helicase FGF60_RS08595 ENOG4105WXT Conserved Protein FGF60_RS08600 ENOG410689M (LipO)protein FGF60_RS08605 ENOG4107H52 Dicarboxylate transport FGF60_RS08610 ENOG4105C5I Dehydrogenase FGF60_RS08615 ENOG41090X5 Heat shock protein hslJ FGF60_RS08620 ENOG4105IKK cytoplasmic protein FGF60_RS08630 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FGF60_RS08635 ENOG4108RW8 Universal stress protein F FGF60_RS08640 ENOG410814C multidrug resistance protein FGF60_RS08660 ENOG4105C1J atp-dependent rna helicase FGF60_RS08675 ENOG4105C8Q Methyl-accepting chemotaxis FGF60_RS08680 ENOG4108DG9 Smr protein MutS2 FGF60_RS08685 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FGF60_RS08690 ENOG4105DS0 Transcriptional regulator, Crp Fnr family FGF60_RS08695 ENOG4105Q9Y Universal stress protein FGF60_RS08700 ENOG4105S5I Membrane FGF60_RS08705 ENOG4105D64 Mechanosensitive ion channel FGF60_RS08725 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FGF60_RS08745 ENOG4106PHM regulatory protein FGF60_RS08760 ENOG4108XFH Transcriptional regulator FGF60_RS08765 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FGF60_RS08770 ENOG4105CV8 reductase FGF60_RS08775 ENOG4105HEI LysR family (Transcriptional regulator FGF60_RS08785 ENOG4107QSI ABC, transporter FGF60_RS08790 ENOG4105KXI murein peptide amidase A FGF60_RS08795 ENOG4107S8C mandelate racemase muconate lactonizing FGF60_RS08800 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FGF60_RS08805 ENOG4108JU8 Transcriptional regulator FGF60_RS08810 ENOG4106K28 UPF0283 membrane protein FGF60_RS08815 ENOG4105CM6 amino acid regulated cytosolic protein FGF60_RS08820 ENOG4105K8Z Phage shock protein FGF60_RS08825 ENOG4105NNG Peripheral inner membrane phage-shock protein FGF60_RS08830 ENOG4105FM1 phage shock protein C FGF60_RS08835 ENOG4105YYT phage shock protein B FGF60_RS08840 ENOG41087YS Phage shock protein A FGF60_RS08845 ENOG4105E51 psp operon transcriptional activator FGF60_RS08850 ENOG4108J59 Extracellular solute-binding protein, family 5 FGF60_RS08855 ENOG4108EKA peptide transport system, permease FGF60_RS08860 ENOG4108EU3 peptide transport system, permease FGF60_RS08865 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein FGF60_RS08870 ENOG4108JQ2 peptide transport system atp-binding protein FGF60_RS08895 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FGF60_RS08900 ENOG4105Q4T oxidoreductase FGF60_RS08910 ENOG4105BZU Histidine kinase FGF60_RS08920 ENOG4105N2W Transcriptional regulator FGF60_RS08925 ENOG41061RM osmotically inducible lipoprotein FGF60_RS08930 ENOG4108ZJT translation initiation factor, Sui1 FGF60_RS08935 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) FGF60_RS08940 ENOG4105CFV Tetratricopeptide repeat protein FGF60_RS08945 ENOG4105Q4A inner membrane protein yciS FGF60_RS08950 ENOG4105EYK Phosphatidylglycerophosphatase B FGF60_RS08955 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) FGF60_RS08960 ENOG4107QM5 aconitate hydratase FGF60_RS08975 ENOG4107R11 Transcriptional regulator FGF60_RS08980 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FGF60_RS08985 ENOG4105RKX Protein of unknown function (DUF2498) FGF60_RS08990 ENOG4105ERU peptidase FGF60_RS08995 ENOG4105UBK short-chain dehydrogenase reductase FGF60_RS09000 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FGF60_RS09005 ENOG4105FE9 pseudouridine synthase FGF60_RS09010 ENOG4107RTD sua5 ycio yrdc ywlc family protein FGF60_RS09015 ENOG4105DB7 PHP domain protein FGF60_RS09025 ENOG4105CRQ synthase (Component I) FGF60_RS09030 ENOG4108EFP Anthranilate synthase component II FGF60_RS09035 ENOG4105DK0 Indole-3-glycerol phosphate synthase FGF60_RS09045 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) FGF60_RS09055 ENOG4108Z9Z response to DNA damage stimulus FGF60_RS09060 ENOG4108N8X transition metal ion binding FGF60_RS09065 ENOG4105WEF catalase FGF60_RS09070 ENOG4105EIF outer membrane protein W FGF60_RS09075 ENOG4105PI0 Ferredoxin FGF60_RS09090 ENOG4105NAU thioesterase Superfamily protein FGF60_RS09095 ENOG410822N TonB family FGF60_RS09100 ENOG4105K9H YciI-like protein FGF60_RS09120 ENOG4105EYW Ion transport protein FGF60_RS09125 ENOG4108JQ7 (ABC) transporter FGF60_RS09130 ENOG4105C3U ABC transporter FGF60_RS09135 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FGF60_RS09140 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FGF60_RS09145 ENOG4107QSI ABC, transporter FGF60_RS09150 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FGF60_RS09155 ENOG4105C0A alcohol dehydrogenase FGF60_RS09170 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FGF60_RS09175 ENOG4105I93 response regulator FGF60_RS09180 ENOG4105D78 K07001 NTE family protein FGF60_RS09185 ENOG4105K5B UPF0225 protein FGF60_RS09190 ENOG4105CIY formyltetrahydrofolate deformylase FGF60_RS09235 ENOG41076YT nitrate reductase, gamma subunit FGF60_RS09240 ENOG4105R3A Nitrate reductase FGF60_RS09245 ENOG4108IUE nitrate reductase beta subunit FGF60_RS09250 ENOG4105CRU nitrate reductase, alpha subunit FGF60_RS09255 ENOG4105DQQ Major facilitator superfamily MFS_1 FGF60_RS09260 ENOG4105BZU Histidine kinase FGF60_RS09265 ENOG4105WH1 Two component transcriptional regulator luxr family FGF60_RS09270 ENOG4105ID0 Putative invasin FGF60_RS09275 ENOG41090EX DsrE family FGF60_RS09280 ENOG4105WS7 Cation transport regulator FGF60_RS09285 ENOG4105EWV Sodium calcium exchanger membrane region FGF60_RS09295 ENOG41063JG Transcriptional regulator FGF60_RS09300 ENOG4108YY7 Invasion gene expression up-regulator SirB FGF60_RS09305 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FGF60_RS09315 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) FGF60_RS09325 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FGF60_RS09330 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FGF60_RS09335 ENOG4105CHH sulfate transporter FGF60_RS09340 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria FGF60_RS09350 ENOG4105C3G gtp-binding protein FGF60_RS09360 ENOG4105E3S small subunit FGF60_RS09370 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit FGF60_RS09375 ENOG4108USZ hydrogenase FGF60_RS09380 ENOG4108VXY Hydrogenase-1 operon protein HyaE FGF60_RS09385 ENOG4105MVP hydrogenase-1 operon protein HyaF FGF60_RS09390 ENOG4105C4M (Ubiquinol oxidase) subunit I FGF60_RS09395 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FGF60_RS09405 ENOG4105D82 Glutamate dehydrogenase FGF60_RS09420 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) FGF60_RS09430 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FGF60_RS09440 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FGF60_RS09450 ENOG4105ED1 spovr family FGF60_RS09465 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) FGF60_RS09475 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation FGF60_RS09490 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FGF60_RS09505 ENOG4107QMS site-determining protein FGF60_RS09515 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FGF60_RS09520 ENOG4105CEY Amp-dependent synthetase and ligase FGF60_RS09525 ENOG4105Y4Z Outer Membrane Lipoprotein FGF60_RS09530 ENOG41072GX Peptidase M22 Glycoprotease FGF60_RS09535 ENOG4105DVT helicase FGF60_RS09540 ENOG4105M4H endoribonuclease L-psp FGF60_RS09545 ENOG4105X5C UPF0181 protein FGF60_RS09550 ENOG4105CRQ synthase (Component I) FGF60_RS09560 ENOG4105EJQ L-serine dehydratase FGF60_RS09565 ENOG4107XTP (EAL) domain protein FGF60_RS09570 ENOG4105EE5 Membrane protein terC FGF60_RS09575 ENOG4105DAS pts system FGF60_RS09580 ENOG4105ETZ PTS System FGF60_RS09585 ENOG4105F3R pts system mannose fructose sorbose family iid FGF60_RS09600 ENOG4105DHI Methyltransferase FGF60_RS09605 ENOG4105CJN penicillin-binding protein FGF60_RS09620 ENOG4105Q3Y exported protein FGF60_RS09625 ENOG4106CCY Protein MgrB homolog FGF60_RS09635 ENOG4105J4Q Transcriptional regulator FGF60_RS09640 ENOG4105C0R drug resistance transporter emrb qaca subfamily FGF60_RS09645 ENOG4105D0M Protease HtpX homolog FGF60_RS09650 ENOG4105CN1 protease FGF60_RS09660 ENOG4108ZGC gaf domain protein FGF60_RS09665 ENOG4105H2K paraquat-inducible protein a FGF60_RS09670 ENOG4105DY2 Paraquat-inducible protein b FGF60_RS09675 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FGF60_RS09680 ENOG4105WT8 Protein of unknown function (DUF1480) FGF60_RS09685 ENOG4105UVW uncharacterized protein yebW FGF60_RS09690 ENOG4108R1E Serine threonine protein phosphatase 1 FGF60_RS09700 ENOG4106EWC guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling FGF60_RS09705 ENOG41064WM Uncharacterized protein YcgX FGF60_RS09715 ENOG4105VEV -acetyltransferase FGF60_RS09750 ENOG4105DWP Membrane FGF60_RS09790 ENOG4105UZW Tail fiber assembly protein FGF60_RS09810 ENOG4108YV9 Protein of unknown function (DUF2514) FGF60_RS09820 ENOG41076J9 exonuclease VIII FGF60_RS09830 ENOG4105NKT exported protein FGF60_RS09835 ENOG4108PNC copper resistance FGF60_RS09840 ENOG4105FXM Copper resistance protein FGF60_RS09845 ENOG4105MPK DNA polymerase III subunit theta FGF60_RS09850 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FGF60_RS09855 ENOG4105UMD exodeoxyribonuclease X FGF60_RS09860 ENOG4105CUG Oligopeptidase b FGF60_RS09865 ENOG4108Q2J Inner membrane protein YebE FGF60_RS09870 ENOG4105RSZ secreted protein FGF60_RS09875 ENOG4105X2V dna damage-inducible protein FGF60_RS09880 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR FGF60_RS09885 ENOG4108UHU Aldolase FGF60_RS09890 ENOG4105C01 Dihydroxy-acid dehydratase FGF60_RS09895 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FGF60_RS09900 ENOG4106KNT transcriptional regulator FGF60_RS09905 ENOG4105CA9 Pyruvate kinase FGF60_RS09910 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase FGF60_RS09915 ENOG4105DR5 peptidase FGF60_RS09920 ENOG4105NXV High-affinity zinc uptake system protein FGF60_RS09925 ENOG4105FDK ABC transporter FGF60_RS09930 ENOG4105FAV ABC, transporter FGF60_RS09950 ENOG4107S01 Repressor protein MetJ FGF60_RS09960 ENOG4105CDY transcriptional regulatory protein FGF60_RS09965 ENOG4108TIT dATP pyrophosphohydrolase FGF60_RS09970 ENOG4105C9M aspartyl-trna synthetase FGF60_RS09975 ENOG4105D3W isochorismatase FGF60_RS09980 ENOG41081XQ Conserved Protein FGF60_RS09985 ENOG4105WJG Glutathione FGF60_RS09995 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) FGF60_RS10005 ENOG4106ZCM YecM protein FGF60_RS10020 ENOG4105F5H Glycosyl Hydrolase Family 88 FGF60_RS10025 ENOG4105IRD Flagellar protein FlhE FGF60_RS10030 ENOG4105D7B Flagellar biosynthesis protein flha FGF60_RS10035 ENOG4105D00 flagellar biosynthetic protein flhB FGF60_RS10040 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) FGF60_RS10045 ENOG4108VYJ response regulator receiver protein FGF60_RS10050 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FGF60_RS10055 ENOG4105BZU Histidine kinase FGF60_RS10060 ENOG4105C8Q Methyl-accepting chemotaxis FGF60_RS10065 ENOG4108V3W Chemotaxis protein, CheW FGF60_RS10070 ENOG4105CBS Chea signal transduction histidine kinase FGF60_RS10075 ENOG4105ER2 Ompa motb domain protein FGF60_RS10080 ENOG4107RD7 Flagellar Motor Protein, MotA FGF60_RS10085 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region FGF60_RS10090 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) FGF60_RS10100 ENOG4108VA4 Universal stress protein FGF60_RS10110 ENOG4108K4C ec 3.1.3.12 FGF60_RS10125 ENOG4108UEC Ferritin-like protein FGF60_RS10135 ENOG4105P23 (LipO)protein FGF60_RS10140 ENOG41090A1 ferritin FGF60_RS10145 ENOG4105VVZ metal-binding protein FGF60_RS10150 ENOG4105E0U tyrosine-specific transport protein FGF60_RS10155 ENOG4106RHG Yeca family FGF60_RS10200 ENOG4105WH1 Two component transcriptional regulator luxr family FGF60_RS10210 ENOG4105XVG cytoplasmic protein FGF60_RS10215 ENOG4105VJY transcriptional regulator FGF60_RS10220 ENOG4105CDA abc transporter atp-binding protein FGF60_RS10225 ENOG4105E5Q amino acid AbC transporter FGF60_RS10230 ENOG4105K6H D-cysteine desulfhydrase FGF60_RS10235 ENOG4105EAB amino acid AbC transporter FGF60_RS10240 ENOG4108M9K flagella biosynthesis protein FliZ FGF60_RS10245 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FGF60_RS10250 ENOG4108RS6 transposase FGF60_RS10255 ENOG4108C80 FliB family FGF60_RS10260 ENOG4105I03 Flagellin FGF60_RS10265 ENOG4105DTS flagellar hook-associated FGF60_RS10270 ENOG4105MQ3 flagellar protein FliS FGF60_RS10280 ENOG4105E5K Alpha-amylase FGF60_RS10285 ENOG4105JCU Inherit from NOG: (Lipo)protein FGF60_RS10310 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) FGF60_RS10315 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FGF60_RS10320 ENOG41090PJ Flagellar assembly protein FGF60_RS10325 ENOG4108JIR Flagellum-specific ATP synthase FGF60_RS10330 ENOG4105GSA Flagellar export protein flij FGF60_RS10335 ENOG4105WF4 Flagellar hook-length control protein FGF60_RS10340 ENOG4107ZI8 flagellar basal body-associated protein flil FGF60_RS10345 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FGF60_RS10350 ENOG4105DD5 Flagellar motor switch protein FGF60_RS10355 ENOG4105K0P flagellar biosynthesis protein FGF60_RS10360 ENOG4105CN7 Flagellar biosynthetic protein FliP FGF60_RS10365 ENOG4105VS8 Flagellar biosynthetic protein fliq FGF60_RS10370 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FGF60_RS10375 ENOG4107TKS colanic acid capsular biosynthesis activation protein A FGF60_RS10385 ENOG4105YX3 cellular response to acidity FGF60_RS10390 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase FGF60_RS10395 ENOG4105BZU Histidine kinase FGF60_RS10400 ENOG4105VNZ cytoplasmic protein FGF60_RS10405 ENOG4105CKW Inner membrane protein yedI FGF60_RS10410 ENOG4105FDR Membrane FGF60_RS10415 ENOG41090BB DNA mismatch endonuclease (vsr) FGF60_RS10420 ENOG4105DVF Cytosine-specific methyltransferase FGF60_RS10425 ENOG4105EST Metal Dependent Phosphohydrolase FGF60_RS10430 ENOG4105Y0K Inner membrane protein YedR FGF60_RS10435 ENOG4105FCK Membrane FGF60_RS10450 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FGF60_RS10455 ENOG4105KT5 UmuD protein FGF60_RS10490 ENOG4105W3V DNA-binding, transcriptional regulator FGF60_RS10495 ENOG4105UZW Tail fiber assembly protein FGF60_RS10500 ENOG4105Y9F tail fiber protein FGF60_RS10505 ENOG4105Y0G tail protein FGF60_RS10510 ENOG4108T86 baseplate J family protein FGF60_RS10550 ENOG4105TKZ Tail Sheath FGF60_RS10595 ENOG4105EFC phage portal protein HK97 family FGF60_RS10605 ENOG4105CAR Terminase, large subunit FGF60_RS10635 ENOG4105NVB glycoside hydrolase, family 19 FGF60_RS10660 ENOG4105HGD Antitermination protein FGF60_RS10665 ENOG4108MXB Protein of unknown function (DUF968) FGF60_RS10675 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) FGF60_RS10700 ENOG4106050 phage regulatory protein, rha family FGF60_RS10705 ENOG4108S1U FGF60_RS10735 ENOG4105H40 FGF60_RS10740 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) FGF60_RS10745 ENOG4108R7K Metal Dependent Phosphohydrolase FGF60_RS10840 ENOG4105FYV Amp nucleosidase FGF60_RS10865 ENOG4105UQX Mate efflux family protein FGF60_RS10875 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FGF60_RS10890 ENOG4108YZT Adenosylcobinamide kinase FGF60_RS10895 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) FGF60_RS10900 ENOG4108JJB ABC transporter FGF60_RS10905 ENOG4108V4M Cobalt abc transporter FGF60_RS10910 ENOG4105W4R Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) FGF60_RS10915 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) FGF60_RS10920 ENOG4105DVK Precorrin-2 c20-methyltransferase FGF60_RS10925 ENOG4107PPM cobalt chelatase FGF60_RS10930 ENOG4105QUC reductase FGF60_RS10935 ENOG4105E4R Precorrin-3B C17-methyltransferase FGF60_RS10940 ENOG4108P62 biosynthesis protein (CbiG) FGF60_RS10945 ENOG4105CIA precorrin-4 C(11)-methyltransferase FGF60_RS10950 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase FGF60_RS10955 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase FGF60_RS10965 ENOG41081F0 Precorrin-8x methylmutase FGF60_RS10970 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) FGF60_RS10975 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) FGF60_RS10980 ENOG4107XVH Transcriptional regulator FGF60_RS10985 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FGF60_RS10990 ENOG4105KNY Microcompartments protein FGF60_RS10995 ENOG4105EHR propanediol utilization protein pduB FGF60_RS11000 ENOG4105DMB glycerol dehydratase FGF60_RS11005 ENOG4105YCI dehydratase medium subunit FGF60_RS11010 ENOG4108ZFT Dehydratase small subunit FGF60_RS11015 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit FGF60_RS11025 ENOG4105KNY Microcompartments protein FGF60_RS11035 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) FGF60_RS11045 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml FGF60_RS11055 ENOG4108EKI Dehydrogenase FGF60_RS11060 ENOG4105C0A alcohol dehydrogenase FGF60_RS11065 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) FGF60_RS11075 ENOG4105M3W utilization protein FGF60_RS11080 ENOG4105KTW ethanolamine utilization protein FGF60_RS11085 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FGF60_RS11090 ENOG4105JZC GHMP kinase FGF60_RS11095 ENOG41090HJ UPF0265 protein FGF60_RS11100 ENOG4105DR8 Membrane FGF60_RS11105 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) FGF60_RS11110 ENOG4105DZ1 carboxypeptidase FGF60_RS11115 ENOG4108NWD Cytochrome FGF60_RS11120 ENOG4105QAX Iron-sulfur FGF60_RS11125 ENOG4108J2R molybdopterin oxidoreductase FGF60_RS11140 ENOG4105CJB Exodeoxyribonuclease I FGF60_RS11145 ENOG4105CUB amino acid FGF60_RS11155 ENOG4105EQ1 Transcriptional regulator FGF60_RS11160 ENOG4107SRH Nad-dependent epimerase dehydratase FGF60_RS11175 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FGF60_RS11180 ENOG4105CIH Imidazole acetol-phosphate transaminase FGF60_RS11185 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FGF60_RS11190 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FGF60_RS11205 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FGF60_RS11210 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) FGF60_RS11215 ENOG4105C6Y Udp-glucose 6-dehydrogenase FGF60_RS11220 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FGF60_RS11225 ENOG4105D3Q Sugar transferase FGF60_RS11230 ENOG4106ECQ phosphomannomutase FGF60_RS11235 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FGF60_RS11240 ENOG4108KBE Glycosyl transferase, family 2 FGF60_RS11245 ENOG4108TJN glycosyl transferase group 1 FGF60_RS11250 ENOG4107YYJ Glycosyl transferase, family 2 FGF60_RS11255 ENOG4105FB1 Polysaccharide Biosynthesis Protein FGF60_RS11260 ENOG4108SMP Nad-dependent epimerase dehydratase FGF60_RS11265 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FGF60_RS11270 ENOG4105FAW cDP-glucose 4,6-dehydratase FGF60_RS11275 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase FGF60_RS11280 ENOG4107QK7 reductase FGF60_RS11300 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FGF60_RS11305 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FGF60_RS11310 ENOG4105C1B dTDP-glucose 4-6-dehydratase FGF60_RS11315 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FGF60_RS11320 ENOG4105G1A colanic acid biosynthesis protein FGF60_RS11325 ENOG4107T8Q Glycosyl transferase (Group 1 FGF60_RS11330 ENOG4105C74 pyruvyl transferase FGF60_RS11335 ENOG4105PSV Polysaccharide Biosynthesis Protein FGF60_RS11340 ENOG4105D3Q Sugar transferase FGF60_RS11345 ENOG4107QKV phosphomannomutase FGF60_RS11350 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FGF60_RS11355 ENOG4106CD9 glycosyl transferase group 1 FGF60_RS11360 ENOG4105FGF GDP-mannose mannosyl hydrolase FGF60_RS11365 ENOG4105C30 Nad-dependent epimerase dehydratase FGF60_RS11370 ENOG4105C0K Gdp-mannose 4,6-dehydratase FGF60_RS11375 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF FGF60_RS11380 ENOG4105ECJ Glycosyl Transferase FGF60_RS11385 ENOG4108NYJ Colanic acid FGF60_RS11390 ENOG4107RXY Glycosyl transferase FGF60_RS11395 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB FGF60_RS11400 ENOG41090RK glycosyl transferase FGF60_RS11405 ENOG4105D75 Capsular exopolysaccharide family FGF60_RS11410 ENOG4105KJF protein tyrosine phosphatase FGF60_RS11415 ENOG4105DAY polysaccharide export protein FGF60_RS11420 ENOG4105EE5 Membrane protein terC FGF60_RS11425 ENOG4108GAE asmA family FGF60_RS11440 ENOG4105BZU Histidine kinase FGF60_RS11445 ENOG4105D03 DNA-3-methyladenine glycosylase II FGF60_RS11450 ENOG4105R8A Heat shock protein FGF60_RS11460 ENOG4105ENT Efflux transporter rnd family, mfp subunit FGF60_RS11465 ENOG4105BZS acriflavin resistance protein FGF60_RS11470 ENOG4105BZS acriflavin resistance protein FGF60_RS11475 ENOG4105C0R drug resistance transporter emrb qaca subfamily FGF60_RS11480 ENOG4105EB3 Histidine kinase FGF60_RS11485 ENOG4105E3W Two component transcriptional regulator (Winged helix family FGF60_RS11505 ENOG4105CFP Peptidase U32 FGF60_RS11535 ENOG4105UZW Tail fiber assembly protein FGF60_RS11540 ENOG4108X9F tail fiber protein FGF60_RS11640 ENOG4105ED4 portal protein FGF60_RS11685 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FGF60_RS11695 ENOG41090V3 Tir chaperone protein (CesT) family FGF60_RS11710 ENOG4105EIE fructose-bisphosphate aldolase FGF60_RS11715 ENOG4105EAA nucleoside FGF60_RS11720 ENOG4108KD5 ADP-ribosylation crystallin J1 FGF60_RS11725 ENOG4108TFM Kinase, PfkB family FGF60_RS11730 ENOG4105FDP GntR family transcriptional regulator FGF60_RS11735 ENOG4105DWF phosphomethylpyrimidine kinase FGF60_RS11745 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly FGF60_RS11750 ENOG410662B Type-1 fimbrial protein FGF60_RS11755 ENOG4105CW0 outer membrane usher protein FGF60_RS11760 ENOG4108MQF Chaperone FGF60_RS11775 ENOG4105D1F ATP-binding protein FGF60_RS11785 ENOG4108YCW (LipO)protein FGF60_RS11795 ENOG4108W15 Protein of unknown function (DUF1456) FGF60_RS11800 ENOG4108NEV two component transcriptional regulator, LytTR family FGF60_RS11805 ENOG4108HRK Histidine kinase FGF60_RS11820 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component FGF60_RS11825 ENOG4108IJ8 ABC transporter FGF60_RS11830 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component FGF60_RS11835 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system FGF60_RS11840 ENOG4107QK4 glycoside hydrolase, family 3 domain protein FGF60_RS11845 ENOG4105CXG d-lactate dehydrogenase FGF60_RS11850 ENOG41061WM D-Alanyl-D-Alanine FGF60_RS11855 ENOG41069YE inner membrane protein yohC FGF60_RS11860 ENOG4105KHU inner membrane protein YohD FGF60_RS11865 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FGF60_RS11870 ENOG4105ETP RND efflux system, outer membrane lipoprotein FGF60_RS11880 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FGF60_RS11885 ENOG4105MSY salicylate hydroxylase FGF60_RS11890 ENOG4108RXX maleylacetoacetate isomerase FGF60_RS11920 ENOG41067MG lrgb family FGF60_RS11930 ENOG4107GZ4 SanA protein FGF60_RS11935 ENOG4105Y9N Membrane FGF60_RS11940 ENOG4105BZ8 glutamate synthase FGF60_RS11945 ENOG4107SJI Dehydrogenase FGF60_RS11950 ENOG4107SDZ Galactoside transport system permease protein mglC FGF60_RS11955 ENOG4105C2J ABC transporter FGF60_RS11960 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FGF60_RS11965 ENOG41060NJ transcriptional regulator FGF60_RS11970 ENOG4105DHF Membrane FGF60_RS11975 ENOG4105EUJ GTP cyclohydrolase i FGF60_RS11990 ENOG4105EJQ L-serine dehydratase FGF60_RS11995 ENOG4105EAC phosphoserine phosphatase FGF60_RS12000 ENOG4105CXY transporter FGF60_RS12005 ENOG4105D05 Receptor FGF60_RS12010 ENOG4108IQI permease FGF60_RS12015 ENOG4105DUM transcriptional regulator, lysR family FGF60_RS12020 ENOG4105HMI Membrane FGF60_RS12030 ENOG4105DM4 PTS System FGF60_RS12035 ENOG4105DE4 1-phosphofructokinase FGF60_RS12040 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FGF60_RS12045 ENOG4105S8Q sugar efflux transporter FGF60_RS12060 ENOG4105KRS Proteinase inhibitor FGF60_RS12065 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FGF60_RS12070 ENOG4105CKI cobalamin synthesis protein FGF60_RS12075 ENOG41076MN Phosphoesterase, PA-phosphatase related FGF60_RS12080 ENOG4107TT5 NLP P60 protein FGF60_RS12085 ENOG4105CXC rtn protein FGF60_RS12090 ENOG4105E43 Extracellular solute-binding protein, family 5 FGF60_RS12095 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FGF60_RS12100 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FGF60_RS12105 ENOG4108JQ5 ABC transporter FGF60_RS12110 ENOG4105HG6 FGF60_RS12115 ENOG4105C2C drug resistance transporter, Bcr CflA FGF60_RS12120 ENOG4105I08 Pseudouridine synthase FGF60_RS12125 ENOG4105CFI type iii restriction protein res subunit FGF60_RS12150 ENOG4105E68 Sulfatase FGF60_RS12160 ENOG4105KT5 UmuD protein FGF60_RS12165 ENOG4105Y50 Virulence Protein FGF60_RS12180 ENOG4105Y9F tail fiber protein FGF60_RS12205 ENOG4105HRS Antitermination protein FGF60_RS12210 ENOG4108MXB Protein of unknown function (DUF968) FGF60_RS12230 ENOG4108X9F tail fiber protein FGF60_RS12245 ENOG4105WH1 Two component transcriptional regulator luxr family FGF60_RS12250 ENOG4105KWW Biogenesis protein FGF60_RS12255 ENOG4107QX9 Thiol disulfide interChange protein FGF60_RS12270 ENOG4105DA4 cytochrome c-type biogenesis protein FGF60_RS12280 ENOG4105X3C heme exporter protein FGF60_RS12285 ENOG41060IM Heme exporter protein FGF60_RS12290 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) FGF60_RS12295 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) FGF60_RS12300 ENOG4105CUW cytochrome C-TYPE protein FGF60_RS12305 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) FGF60_RS12310 ENOG4105GXZ Ferredoxin-type protein NapH FGF60_RS12315 ENOG4108BGM Quinol dehydrogenase periplasmic component FGF60_RS12325 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase FGF60_RS12330 ENOG4108ZNS ferredoxin-type protein NapF FGF60_RS12340 ENOG4105IBP Cyclic peptide transporter FGF60_RS12345 ENOG4105CF1 Alkylated DNA repair protein FGF60_RS12350 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FGF60_RS12355 ENOG4105CJ2 (LipO)protein FGF60_RS12360 ENOG4105FCK Membrane FGF60_RS12365 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC FGF60_RS12370 ENOG41068CG regulatoR FGF60_RS12375 ENOG4105BZU Histidine kinase FGF60_RS12380 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FGF60_RS12385 ENOG4105CXK mandelate racemase muconate lactonizing FGF60_RS12405 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FGF60_RS12410 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FGF60_RS12415 ENOG4105XPH Ferredoxin FGF60_RS12420 ENOG4105CZM Major Facilitator FGF60_RS12425 ENOG4105GZI Transcriptional regulator FGF60_RS12430 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FGF60_RS12435 ENOG4105CXY transporter FGF60_RS12440 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A FGF60_RS12450 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FGF60_RS12455 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is FGF60_RS12470 ENOG4105CSP Major Facilitator Superfamily FGF60_RS12475 ENOG4105CXK mandelate racemase muconate lactonizing FGF60_RS12480 ENOG4107258 Transcriptional regulator FGF60_RS12485 ENOG4108EWA cinA-like protein FGF60_RS12490 ENOG4108UII YfaZ family FGF60_RS12515 ENOG4105C3I Nad-dependent epimerase dehydratase FGF60_RS12520 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) FGF60_RS12525 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) FGF60_RS12540 ENOG4106GZG polymyxin resistance protein B FGF60_RS12545 ENOG4105CEY Amp-dependent synthetase and ligase FGF60_RS12550 ENOG4105DNI Converts SHCHC to OSB (By similarity) FGF60_RS12555 ENOG4108IPT Naphthoate synthase FGF60_RS12560 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FGF60_RS12570 ENOG4105E4F Isochorismate synthase FGF60_RS12575 ENOG4105TNS Conserved Protein FGF60_RS12580 ENOG4107YB6 acetyltransferase, (GNAT) family FGF60_RS12595 ENOG4105CP2 von willebrand factor, type a FGF60_RS12610 ENOG4105C8S subunit m FGF60_RS12615 ENOG4105D65 subunit l FGF60_RS12625 ENOG4107UFS subunit j FGF60_RS12640 ENOG4108IEH NADH dehydrogenase subunit g FGF60_RS12645 ENOG4107QIZ NADH dehydrogenase FGF60_RS12650 ENOG4105GKE subunit e FGF60_RS12660 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FGF60_RS12665 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FGF60_RS12675 ENOG4107NQ8 LysR family Transcriptional regulator FGF60_RS12680 ENOG4105CHM Aminotransferase FGF60_RS12695 ENOG4107QWE )-transporter FGF60_RS12700 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 FGF60_RS12715 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FGF60_RS12720 ENOG4105C6K Malic enzyme FGF60_RS12725 ENOG4105CSX c4-dicarboxylate anaerobic carrier FGF60_RS12730 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) FGF60_RS12735 ENOG4108HHA Transketolase FGF60_RS12740 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FGF60_RS12750 ENOG4106ETB IIa component FGF60_RS12755 ENOG4105K2J Transcriptional regulator FGF60_RS12760 ENOG4105PTV Nudix Hydrolase FGF60_RS12765 ENOG4108RE9 Phosphodiesterase FGF60_RS12770 ENOG4108SHQ Glutathione S-transferase FGF60_RS12775 ENOG4105CYM Glutathione S-transferase FGF60_RS12780 ENOG4105ECP epimerase FGF60_RS12785 ENOG4108JEH abc transporter atp-binding protein FGF60_RS12790 ENOG4106YG3 ABC transporter FGF60_RS12795 ENOG4105DSP amino acid AbC transporter FGF60_RS12800 ENOG4105E89 ABC transporter FGF60_RS12805 ENOG4105E89 ABC transporter FGF60_RS12810 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FGF60_RS12820 ENOG4106M28 alanine racemase domain protein FGF60_RS12825 ENOG4105E5D amino acid FGF60_RS12835 ENOG4108JUB Transcriptional regulator FGF60_RS12840 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FGF60_RS12845 ENOG4105E96 Colicin v production protein FGF60_RS12850 ENOG4108S3P Sporulation domain protein FGF60_RS12855 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FGF60_RS12865 ENOG4105DQR SNARE associated Golgi FGF60_RS12870 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FGF60_RS12875 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FGF60_RS12885 ENOG4106WZ1 flagella biosynthesis regulator FGF60_RS12890 ENOG4105F9N Major Facilitator Superfamily FGF60_RS12900 ENOG4105R8V Transcriptional regulator FGF60_RS12920 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FGF60_RS12925 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) FGF60_RS12930 ENOG4105MH2 YfcL protein FGF60_RS12935 ENOG4108BPE -transporting atpase FGF60_RS12940 ENOG4105EJ9 Membrane FGF60_RS12955 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) FGF60_RS12965 ENOG4108BY2 phosphohistidine phosphatase FGF60_RS12970 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FGF60_RS12975 ENOG4105CHU acetyl-coa acetyltransferase FGF60_RS12980 ENOG4105KZW UPF0381 protein FGF60_RS12985 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation FGF60_RS12990 ENOG410903C (LipO)protein FGF60_RS12995 ENOG4105S64 Formate nitrite transporter FGF60_RS13005 ENOG4108NC2 Outer membrane protease FGF60_RS13010 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta FGF60_RS13020 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC FGF60_RS13025 ENOG4105CXY transporter FGF60_RS13030 ENOG4105W9M Membrane FGF60_RS13035 ENOG4105D1S lipid A biosynthesis FGF60_RS13045 ENOG4108RS6 transposase FGF60_RS13050 ENOG4105CHM Aminotransferase FGF60_RS13065 ENOG4107RA9 decarboxylase FGF60_RS13070 ENOG4105CPC Aldo Keto reductase FGF60_RS13075 ENOG4109076 Conserved Protein FGF60_RS13085 ENOG4105D9N nucleoside FGF60_RS13090 ENOG4108KMM Diguanylate cyclase FGF60_RS13105 ENOG4105HZG regulatoR FGF60_RS13110 ENOG4105GXM Putative transcription regulator (DUF1323) FGF60_RS13140 ENOG4105CN8 Transcriptional regulator FGF60_RS13150 ENOG4105EAA nucleoside FGF60_RS13155 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) FGF60_RS13160 ENOG4108NFH Sugar hydrolase FGF60_RS13165 ENOG4108M0I Transcriptional regulator FGF60_RS13170 ENOG4105DHU Bile acid FGF60_RS13175 ENOG4105VRT cytoplasmic protein FGF60_RS13180 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FGF60_RS13190 ENOG4105EXN Sulfate transport protein CysZ FGF60_RS13195 ENOG4105C6T cysteine synthase FGF60_RS13205 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FGF60_RS13210 ENOG4105C5Y PTS System FGF60_RS13220 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) FGF60_RS13225 ENOG4105CSW GntR family transcriptional regulator FGF60_RS13230 ENOG41089BK Glutamine amido-transferase FGF60_RS13235 ENOG4105M0Y FGF60_RS13245 ENOG4105C6T cysteine synthase FGF60_RS13250 ENOG4108IJ6 ABC transporter FGF60_RS13255 ENOG4105ECW sulfate abc transporter FGF60_RS13260 ENOG4108I5D sulfate abc transporter FGF60_RS13265 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein FGF60_RS13270 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FGF60_RS13275 ENOG4105EZR dyp-type peroxidase family protein FGF60_RS13280 ENOG4105E7K (LipO)protein FGF60_RS13285 ENOG4105QZU Inner membrane protein YfeZ FGF60_RS13290 ENOG4108R6G acetyltransferase FGF60_RS13295 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase FGF60_RS13310 ENOG4107H8F FGF60_RS13315 ENOG4108K3Z AraC family transcriptional regulator FGF60_RS13320 ENOG4108X49 Ethanolamine utilization protein EutK FGF60_RS13325 ENOG4106D67 ethanolamine utilization protein FGF60_RS13335 ENOG4105CPD ethanolamine ammonia-lyase FGF60_RS13340 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase FGF60_RS13345 ENOG4105ENY Ethanolamine utilization protein eutH FGF60_RS13350 ENOG4105C0A alcohol dehydrogenase FGF60_RS13355 ENOG4107YMV ethanolamine utilization protein FGF60_RS13360 ENOG4108EKI Dehydrogenase FGF60_RS13365 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml FGF60_RS13370 ENOG4105KNY Microcompartments protein FGF60_RS13375 ENOG4108IJ2 phosphate acetyltransferase FGF60_RS13380 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase FGF60_RS13385 ENOG4105NDK ethanolamine utilization protein FGF60_RS13390 ENOG4106S4J ethanolamine utilization protein EutP FGF60_RS13395 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place FGF60_RS13400 ENOG4108RS6 transposase FGF60_RS13405 ENOG4105C6K Malic enzyme FGF60_RS13410 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FGF60_RS13415 ENOG4105CV1 Transketolase (EC 2.2.1.1) FGF60_RS13425 ENOG4108PVD exported protein FGF60_RS13430 ENOG4107VIJ nudix hydrolase FGF60_RS13435 ENOG4107QK9 Beta-lactamase FGF60_RS13440 ENOG4105BZ8 glutamate synthase FGF60_RS13445 ENOG4105BZU Histidine kinase FGF60_RS13450 ENOG4105BZS acriflavin resistance protein FGF60_RS13460 ENOG4105KUZ arsenate reductase FGF60_RS13465 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) FGF60_RS13475 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) FGF60_RS13480 ENOG4105CGZ zinc metallopeptidase FGF60_RS13490 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FGF60_RS13500 ENOG4105RH4 Glycine cleavage system transcriptional repressor FGF60_RS13505 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FGF60_RS13510 ENOG4105BZW Glycerate kinase FGF60_RS13515 ENOG4105C02 permease FGF60_RS13520 ENOG4105ERG peptidase m48, ste24p FGF60_RS13525 ENOG4105K89 arsenate reductase FGF60_RS13535 ENOG4105C2W permease FGF60_RS13540 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) FGF60_RS13555 ENOG4108V3E phosphoribosylglycinamide formyltransferase FGF60_RS13560 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FGF60_RS13565 ENOG4105C9X ppx gppa phosphatase FGF60_RS13570 ENOG4105BZU Histidine kinase FGF60_RS13580 ENOG41062G3 Protein of unknown function (DUF2633) FGF60_RS13610 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FGF60_RS13615 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FGF60_RS13650 ENOG4105VPD cellular component movement FGF60_RS13660 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FGF60_RS13665 ENOG4105N21 Membrane FGF60_RS13685 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs FGF60_RS13705 ENOG4105QAX Iron-sulfur FGF60_RS13710 ENOG4107QY8 reductase FGF60_RS13715 ENOG4108JQB penicillin-binding protein 1C FGF60_RS13720 ENOG4105DN3 alpha-2-macroglobulin domain protein FGF60_RS13725 ENOG4105KHC sulfurtransferase FGF60_RS13735 ENOG4105YYA enhanced serine sensitivity protein SseB FGF60_RS13745 ENOG4105WVQ Fe-S assembly protein IscX FGF60_RS13750 ENOG4108ZIT Ferredoxin, 2FE-2S FGF60_RS13755 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB FGF60_RS13760 ENOG4108SWN Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity) FGF60_RS13765 ENOG4108Z4V iron-sulfur cluster assembly FGF60_RS13770 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FGF60_RS13785 ENOG4105CVS RNA methyltransferase TrmH family, group 1 FGF60_RS13790 ENOG4105ECY inositol monophosphatase FGF60_RS13795 ENOG4107XM9 (LipO)protein FGF60_RS13800 ENOG4105D5B Sulfite reductase, subunit A FGF60_RS13805 ENOG4107SHJ sulfite reductase subunit b FGF60_RS13810 ENOG410810Y Sulfite reductase FGF60_RS13815 ENOG4105D7X high-affinity nickel-transporter FGF60_RS13825 ENOG4108MN2 Stationary phase inducible protein CsiE FGF60_RS13830 ENOG4105D8G Major Facilitator superfamily FGF60_RS13840 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FGF60_RS13845 ENOG4108M3R transcriptional activator CadC FGF60_RS13850 ENOG4105D5Q Arginine ornithine antiporter FGF60_RS13855 ENOG4105CXN decarboxylase FGF60_RS13860 ENOG4105DUX Transporter FGF60_RS13870 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FGF60_RS13875 ENOG4108SKK alpha helix protein FGF60_RS13880 ENOG4107WP9 Histidine kinase FGF60_RS13890 ENOG4108RS6 transposase FGF60_RS13895 ENOG4108ETH Formylglycinamide ribotide synthetase FGF60_RS13905 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) FGF60_RS13910 ENOG4108Z6B deaminase FGF60_RS13915 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB FGF60_RS13930 ENOG4106G6Q Transcriptional regulator FGF60_RS13935 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FGF60_RS13945 ENOG4105DND Transcriptional regulator FGF60_RS13950 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FGF60_RS13960 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FGF60_RS13980 ENOG4105C3F Signal peptidase i FGF60_RS14020 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FGF60_RS14025 ENOG4108C33 Resolvase FGF60_RS14035 ENOG4105UZW Tail fiber assembly protein FGF60_RS14045 ENOG410685N tail fiber protein FGF60_RS14105 ENOG4105D7V transposase FGF60_RS14125 ENOG4105IM0 capsid protein FGF60_RS14145 ENOG4107DE1 head-to-tail joining protein FGF60_RS14150 ENOG4105UZW Tail fiber assembly protein FGF60_RS14160 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium FGF60_RS14165 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 FGF60_RS14235 ENOG4105MEA DNA damage-inducible protein i FGF60_RS14275 ENOG4107QJE Chromosome Partitioning Protein FGF60_RS14300 ENOG41076J9 exonuclease VIII FGF60_RS14325 ENOG4105WMJ Positive regulator of sigma E, RseC MucC FGF60_RS14355 ENOG4108IYU L-aspartate oxidase FGF60_RS14365 ENOG4105C1J atp-dependent rna helicase FGF60_RS14370 ENOG41090KR LysR family transcriptional Regulator FGF60_RS14380 ENOG4108VKA Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity) FGF60_RS14390 ENOG4105EIB trna rrna methyltransferase FGF60_RS14395 ENOG4105K63 Thioredoxin FGF60_RS14400 ENOG4106IUH DTW domain containing protein FGF60_RS14405 ENOG4105CD5 CoA-binding domain protein FGF60_RS14410 ENOG4105JIM Phosphatidylserine synthase FGF60_RS14415 ENOG4105T42 (LipO)protein FGF60_RS14420 ENOG4105CSH Transporter FGF60_RS14450 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FGF60_RS14455 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FGF60_RS14460 ENOG4105C34 Pseudouridine synthase FGF60_RS14465 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FGF60_RS14470 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA FGF60_RS14480 ENOG4105CQC Prephenate dehydratase FGF60_RS14490 ENOG4105EHE chorismate mutase- prephenate dehydrogenase FGF60_RS14495 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FGF60_RS14500 ENOG4108WS1 FGF60_RS14505 ENOG4108KHX Diguanylate cyclase FGF60_RS14510 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FGF60_RS14530 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FGF60_RS14535 ENOG4106KVJ cytochrome C assembly protein FGF60_RS14540 ENOG4108JU6 CBS domain protein FGF60_RS14560 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FGF60_RS14565 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FGF60_RS14575 ENOG4108Z1B Cyclase dehydrase FGF60_RS14595 ENOG4105BZ1 (ABC) transporter FGF60_RS14610 ENOG4105DFP Integrase FGF60_RS14615 ENOG4105DFP Integrase FGF60_RS14645 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) FGF60_RS14660 ENOG4105HVQ Regulatory factor of maltose metabolism FGF60_RS14665 ENOG410787A Pts system, glucitol sorbitol-specific FGF60_RS14675 ENOG4105DZY Pts system, glucitol sorbitol-specific FGF60_RS14690 ENOG4108VA3 3-hexulose-6-phosphate synthase FGF60_RS14695 ENOG41080HJ 6-phospho 3-hexuloisomerase FGF60_RS14705 ENOG4105CI1 PTS System FGF60_RS14730 ENOG4105DFP Integrase FGF60_RS14765 ENOG4105I03 Flagellin FGF60_RS14770 ENOG4108C33 Resolvase FGF60_RS14795 ENOG4105NIV Esterase FGF60_RS14800 ENOG4107RNH Outer membrane receptor FepA FGF60_RS14810 ENOG4105VRE Pentapeptide repeat protein FGF60_RS14815 ENOG4108MJ5 VirK protein FGF60_RS14915 ENOG4105DHQ Histidine kinase FGF60_RS14945 ENOG4105D5U fad dependent oxidoreductase FGF60_RS14950 ENOG4105C26 Dehydrogenase FGF60_RS14955 ENOG4108JPW Aminotransferase FGF60_RS14960 ENOG4105C85 amino acid FGF60_RS14965 ENOG4108PVQ transcriptional regulator FGF60_RS14970 ENOG4109066 lysm domain bon superfamily protein FGF60_RS14980 ENOG4105VPI YqaE family transport protein FGF60_RS14985 ENOG41080HT Transcriptional regulator, arsr family FGF60_RS14990 ENOG4108V62 Rhodanese domain protein FGF60_RS15000 ENOG4108X73 DNA- binding protein FGF60_RS15010 ENOG4108RNS Exports L-alanine (By similarity) FGF60_RS15015 ENOG4108WMJ Protein of unknown function (DUF2002) FGF60_RS15020 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) FGF60_RS15030 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FGF60_RS15040 ENOG4105WAZ (Glutaredoxin-like protein) NrdH FGF60_RS15050 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FGF60_RS15055 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FGF60_RS15060 ENOG4108IJ7 Glycine betaine FGF60_RS15065 ENOG4108HQS Glycine betaine FGF60_RS15070 ENOG4105GIJ Glycine betaine FGF60_RS15080 ENOG4105NTK Transcriptional repressor Mpra FGF60_RS15085 ENOG4105CW7 secretion protein, HlyD family FGF60_RS15090 ENOG4105C0R drug resistance transporter emrb qaca subfamily FGF60_RS15110 ENOG4105W39 Membrane FGF60_RS15115 ENOG4107VXZ Hydrolase FGF60_RS15145 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FGF60_RS15150 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FGF60_RS15160 ENOG4105Y3E Modulates RecA activity (By similarity) FGF60_RS15170 ENOG4107TH8 cina domain protein FGF60_RS15180 ENOG4105CVE Lytic murein transglycosylase FGF60_RS15185 ENOG410787A Pts system, glucitol sorbitol-specific FGF60_RS15190 ENOG4105DZY Pts system, glucitol sorbitol-specific FGF60_RS15195 ENOG4105VI0 Pts system, glucitol sorbitol-specific FGF60_RS15200 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase FGF60_RS15205 ENOG4105J92 DNA-binding transcriptional activator GutM FGF60_RS15210 ENOG410804X Transcriptional regulator FGF60_RS15215 ENOG4105C2X Arabinose 5-phosphate isomerase FGF60_RS15225 ENOG4108ESE uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center FGF60_RS15230 ENOG4107QZF nitrite reductase NADPH large subunit FGF60_RS15235 ENOG4105C8H hydrogenase maturation protein Hypf FGF60_RS15240 ENOG4108RC0 Electron transport protein FGF60_RS15250 ENOG4108MG9 hydrogenase 3 maturation protease FGF60_RS15255 ENOG4105I6X formate hydrogenlyase maturation FGF60_RS15260 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FGF60_RS15265 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit FGF60_RS15270 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FGF60_RS15275 ENOG4107TDF Formate hydrogenlyase subunit 4 FGF60_RS15280 ENOG4107R30 NADH dehydrogenase FGF60_RS15285 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FGF60_RS15290 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA FGF60_RS15295 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FGF60_RS15300 ENOG4107RSS Hydrogenase accessory protein HypB FGF60_RS15305 ENOG41083WG hydrogenase assembly chaperone FGF60_RS15310 ENOG4105CQS hydrogenase expression formation protein HypD FGF60_RS15315 ENOG4105C45 hydrogenase expression formation protein (HypE) FGF60_RS15325 ENOG4105VXR cytoplasmic protein FGF60_RS15335 ENOG4105DIK (ABC) transporter FGF60_RS15340 ENOG4105CC5 ABC transporter FGF60_RS15345 ENOG4105CC5 ABC transporter FGF60_RS15380 ENOG4108RBT type iii secretion FGF60_RS15385 ENOG4106BTR FGF60_RS15390 ENOG4105Y7Q type iii secretion FGF60_RS15395 ENOG4108RC9 Type III secretion system protein FGF60_RS15405 ENOG4108YAB Invasion protein FGF60_RS15415 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear FGF60_RS15440 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC FGF60_RS15450 ENOG4106H1J Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE FGF60_RS15460 ENOG4108M6W surface presentation of antigens protein SpaS FGF60_RS15465 ENOG4108TN6 type iii secretion FGF60_RS15470 ENOG4105U07 type iii secretion FGF60_RS15475 ENOG41075IY surface presentation of antigens protein SpaP FGF60_RS15480 ENOG4105T85 surface presentation of antigens protein FGF60_RS15485 ENOG41078G4 surface presentation of FGF60_RS15490 ENOG41077MC Secretory protein (Associated with virulence) FGF60_RS15495 ENOG4108JIR Flagellum-specific ATP synthase FGF60_RS15500 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone FGF60_RS15505 ENOG4108HR8 type iii secretion FGF60_RS15510 ENOG4108N8R Invasion protein FGF60_RS15520 ENOG41090HZ type iii secretion FGF60_RS15565 ENOG4105MEW serine threonine protein phosphatase FGF60_RS15585 ENOG4105C0R drug resistance transporter emrb qaca subfamily FGF60_RS15590 ENOG4105JQN Transcriptional regulator FGF60_RS15595 ENOG4105C6Z Gluconate FGF60_RS15600 ENOG4105EXW epimerase dehydratase FGF60_RS15605 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FGF60_RS15615 ENOG4105G63 Type III effector Hrp-dependent FGF60_RS15625 ENOG4105MVE transcriptional regulator FGF60_RS15635 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FGF60_RS15640 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FGF60_RS15645 ENOG4105KZM cytoplasmic protein FGF60_RS15655 ENOG4108K5P (LipO)protein FGF60_RS15675 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FGF60_RS15680 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) FGF60_RS15690 ENOG4105N0Z inner membrane protein ygbE FGF60_RS15700 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) FGF60_RS15710 ENOG4108MXK alkaline phosphatase isozyme conversion FGF60_RS15715 ENOG4105PWE CRISPR-associated protein cas2 FGF60_RS15720 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) FGF60_RS15730 ENOG4108VWQ crispr-associated protein FGF60_RS15735 ENOG41060M0 Crispr-associated protein, cse4 family FGF60_RS15745 ENOG4105CYR Crispr-associated protein, cse1 family FGF60_RS15750 ENOG4105DTT CRISPR-associated helicase, cas3 FGF60_RS15760 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) FGF60_RS15765 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FGF60_RS15770 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FGF60_RS15775 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FGF60_RS15780 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FGF60_RS15785 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FGF60_RS15790 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FGF60_RS15800 ENOG4105DXN mazG family FGF60_RS15815 ENOG4105X54 addiction module antidote protein FGF60_RS15820 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FGF60_RS15825 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FGF60_RS15830 ENOG4105BZU Histidine kinase FGF60_RS15835 ENOG4105BZW Glycerate kinase FGF60_RS15840 ENOG4105EQX glucarate dehydratase FGF60_RS15845 ENOG4105EQX glucarate dehydratase FGF60_RS15850 ENOG4105DJB Major Facilitator Superfamily FGF60_RS15860 ENOG4105QDK Flavodoxin FGF60_RS15865 ENOG4105DR9 pseudouridine synthase FGF60_RS15870 ENOG4105WP7 tRNA pseudouridine synthase C FGF60_RS15885 ENOG4107R1K Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) FGF60_RS15890 ENOG4105EWT decarboxylase family FGF60_RS15895 ENOG4105C44 Serine transporter FGF60_RS15900 ENOG4105EJQ L-serine dehydratase FGF60_RS15910 ENOG4105C0A alcohol dehydrogenase FGF60_RS15915 ENOG4107W7X Aldolase FGF60_RS15920 ENOG4105EDR glucose galactose transporter FGF60_RS15930 ENOG4105CMG Carbohydrate kinase FGF60_RS15935 ENOG4105NWF RbsD or FucU transport FGF60_RS15940 ENOG4107EDW L-fucose operon activator FGF60_RS15950 ENOG4105M08 Membrane FGF60_RS15955 ENOG4105ETT transcriptional Regulator, LysR family FGF60_RS15960 ENOG4105M5B (LipO)protein FGF60_RS15965 ENOG4105C9B Cysteine desulfurase FGF60_RS15970 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) FGF60_RS15975 ENOG4105FR1 rard protein FGF60_RS15980 ENOG4105CUZ uba thif-type nad fad binding protein FGF60_RS15985 ENOG4105CA3 membrane-bound lytic murein transglycosylase FGF60_RS16000 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FGF60_RS16005 ENOG4108EKC n-acetylglutamate synthase FGF60_RS16010 ENOG4107QYX exodeoxyribonuclease v alpha FGF60_RS16015 ENOG4107QKA exodeoxyribonuclease V beta FGF60_RS16020 ENOG4107QXK peptidase FGF60_RS16025 ENOG4105DSY exodeoxyribonuclease V, gamma FGF60_RS16030 ENOG4105RVB Prepilin peptidase dependent protein c FGF60_RS16035 ENOG4105SEN Protein of unknown function (DUF2509) FGF60_RS16040 ENOG4105JCS prepilin peptidase dependent protein FGF60_RS16045 ENOG4105IPU prepilin peptidase dependent protein A FGF60_RS16060 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FGF60_RS16075 ENOG4105EE5 Membrane protein terC FGF60_RS16080 ENOG4105SUV lipoprotein YgdR FGF60_RS16085 ENOG4105CPC Aldo Keto reductase FGF60_RS16095 ENOG4105CEY Amp-dependent synthetase and ligase FGF60_RS16105 ENOG41060NJ transcriptional regulator FGF60_RS16115 ENOG4105RQF LysR family Transcriptional regulator FGF60_RS16125 ENOG4107QNK )-transporter FGF60_RS16130 ENOG4105CHR reductase FGF60_RS16135 ENOG4105D50 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity) FGF60_RS16140 ENOG4105CHU acetyl-coa acetyltransferase FGF60_RS16145 ENOG4105C5Q Transcriptional regulator FGF60_RS16155 ENOG4108MHD transport protein FGF60_RS16185 ENOG4106P2F Pfam:Pili_assembly_C FGF60_RS16205 ENOG4108T1M outer membrane protein x FGF60_RS16215 ENOG4108RS6 transposase FGF60_RS16220 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A FGF60_RS16225 ENOG4105VGJ Virulence-associated protein FGF60_RS16245 ENOG4108K5P (LipO)protein FGF60_RS16265 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FGF60_RS16270 ENOG4105T95 Thiol disulfide interChange protein FGF60_RS16275 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FGF60_RS16280 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) FGF60_RS16285 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB FGF60_RS16295 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) FGF60_RS16300 ENOG4108UT2 hemolysin iii FGF60_RS16310 ENOG4105CS2 ec 3.2.1.21 FGF60_RS16340 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FGF60_RS16345 ENOG4105D0A hydroxylase FGF60_RS16350 ENOG4107RAQ aminopeptidase FGF60_RS16370 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FGF60_RS16375 ENOG4108JQ1 Dehydrogenase FGF60_RS16390 ENOG4105MPN Membrane FGF60_RS16400 ENOG4105D64 Mechanosensitive ion channel FGF60_RS16405 ENOG4105D2N Aldolase FGF60_RS16410 ENOG4105BZA Phosphoglycerate kinase FGF60_RS16435 ENOG4108JJB ABC transporter FGF60_RS16440 ENOG4108JJB ABC transporter FGF60_RS16445 ENOG4105CV1 Transketolase (EC 2.2.1.1) FGF60_RS16450 ENOG4108K0D peptidase, M48 FGF60_RS16460 ENOG4108MXF Alpha Beta Hydrolase FGF60_RS16465 ENOG4108R66 Conserved Protein FGF60_RS16470 ENOG4105DG4 malate L-lactate dehydrogenase FGF60_RS16475 ENOG4105CPQ Dehydrogenase FGF60_RS16480 ENOG4105DEI Mannitol dehydrogenase FGF60_RS16490 ENOG4107YCY Transcriptional regulator FGF60_RS16500 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) FGF60_RS16520 ENOG4107QNK )-transporter FGF60_RS16530 ENOG4105RWS endonuclease I FGF60_RS16535 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FGF60_RS16540 ENOG4105D7Z glutathione synthase FGF60_RS16560 ENOG4105CZX twitching motility protein FGF60_RS16565 ENOG4105DFA alanine racemase domain protein FGF60_RS16570 ENOG4108VIA integral membrane protein FGF60_RS16575 ENOG4105VZ9 UPF0235 protein FGF60_RS16585 ENOG4105CSA Coproporphyrinogen iii oxidase FGF60_RS16590 ENOG4106MH3 alpha helix chain FGF60_RS16595 ENOG4105HDK L-asparaginase FGF60_RS16600 ENOG4105K33 Periplasmic Protein FGF60_RS16605 ENOG41090ED Protein with unknown function (DUF469) FGF60_RS16610 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FGF60_RS16615 ENOG4105CEN a g-specific adenine glycosylase FGF60_RS16620 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) FGF60_RS16630 ENOG4105EAA nucleoside FGF60_RS16635 ENOG4105CXN decarboxylase FGF60_RS16640 ENOG4108UQV Membrane FGF60_RS16650 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase FGF60_RS16655 ENOG4105CYC Transferase FGF60_RS16660 ENOG4105DJG MaoC domain protein dehydratase FGF60_RS16665 ENOG4105CI0 Citrate lyase FGF60_RS16675 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) FGF60_RS16685 ENOG4108UAJ Transcriptional regulator FGF60_RS16695 ENOG4105CUB amino acid FGF60_RS16705 ENOG4105CJP fad dependent oxidoreductase FGF60_RS16710 ENOG4105C26 Dehydrogenase FGF60_RS16735 ENOG4105DPW Major facilitator superfamily MFS_1 FGF60_RS16745 ENOG4105DEI Mannitol dehydrogenase FGF60_RS16760 ENOG4106032 Glutathionylspermidine synthase FGF60_RS16765 ENOG4105CYM Glutathione S-transferase FGF60_RS16770 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein FGF60_RS16775 ENOG4105S10 periplasmic binding protein FGF60_RS16780 ENOG41082MF Hydrogenase assembly chaperone hypC hupF FGF60_RS16785 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FGF60_RS16790 ENOG4108WGS hydrogenase 2-specific chaperone FGF60_RS16795 ENOG4108USZ hydrogenase FGF60_RS16800 ENOG4105DPX Hydrogenase, large subunit FGF60_RS16805 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit FGF60_RS16810 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FGF60_RS16815 ENOG4105E3S small subunit FGF60_RS16820 ENOG410900S Protein of unknown function (DUF2623) FGF60_RS16825 ENOG4105C8Q Methyl-accepting chemotaxis FGF60_RS16850 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FGF60_RS16855 ENOG4108ZZF transport protein (ExbD) FGF60_RS16860 ENOG4105CWK Biopolymer transport protein, ExbB FGF60_RS16865 ENOG4105C28 cystathionine FGF60_RS16870 ENOG4108K81 inner membrane protein YghB FGF60_RS16875 ENOG4105CF7 AraC family transcriptional regulator FGF60_RS16880 ENOG4108I6A alcohol dehydrogenase FGF60_RS16885 ENOG4105CV8 reductase FGF60_RS16890 ENOG4107QPK )-transporter FGF60_RS16905 ENOG4105CCT upf0313 protein FGF60_RS16910 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FGF60_RS16920 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FGF60_RS16925 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) FGF60_RS16930 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase FGF60_RS16935 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FGF60_RS16940 ENOG4105F4I Transcriptional regulator FGF60_RS16945 ENOG4105H4F exported protein FGF60_RS16950 ENOG4105XJC Two component transcriptional regulator (Winged helix family FGF60_RS16955 ENOG4105DHQ Histidine kinase FGF60_RS16960 ENOG4105NF4 modulator of drug activity FGF60_RS16965 ENOG4105VRH Antibiotic biosynthesis monooxygenase FGF60_RS16970 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FGF60_RS16975 ENOG4105IPS esterase FGF60_RS16980 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FGF60_RS16985 ENOG4108SX3 cytoplasmic protein FGF60_RS16990 ENOG41087AY ADP-Ribose pyrophosphatase FGF60_RS17000 ENOG4105F1G UPF0441 protein FGF60_RS17005 ENOG4106032 Glutathionylspermidine synthase FGF60_RS17010 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FGF60_RS17020 ENOG4108MR7 Arylsulfotransferase FGF60_RS17030 ENOG4108PSN Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity) FGF60_RS17040 ENOG4105W0Z cytoplasmic protein FGF60_RS17050 ENOG4105PV3 Inner membrane protein yqiJ FGF60_RS17055 ENOG4107S78 Band 7 protein FGF60_RS17070 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) FGF60_RS17075 ENOG4105I7R Adenylate cyclase FGF60_RS17080 ENOG4106MWK domain protein FGF60_RS17085 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate FGF60_RS17095 ENOG4107ZVW dihydroneopterin aldolase FGF60_RS17120 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FGF60_RS17125 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FGF60_RS17130 ENOG4108VCA G U mismatch-specific DNA glycosylase FGF60_RS17140 ENOG4105Q26 Siderophore-interacting protein FGF60_RS17145 ENOG4105NTW Transcriptional regulator FGF60_RS17150 ENOG4105C8Q Methyl-accepting chemotaxis FGF60_RS17155 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor FGF60_RS17165 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FGF60_RS17175 ENOG4108VKG metal-dependent hydrolase FGF60_RS17180 ENOG4108UB4 uncharacterized protein ygjQ FGF60_RS17185 ENOG4105EE0 oxidoreductase FGF60_RS17190 ENOG4105DU1 integral membrane protein, terc FGF60_RS17200 ENOG4106W5V Membrane FGF60_RS17210 ENOG4105WAY exported protein FGF60_RS17215 ENOG4105NE1 Conserved Protein FGF60_RS17220 ENOG41090KG Inner membrane protein YqjE FGF60_RS17225 ENOG4105YJD FGF60_RS17230 ENOG4108VBZ doxx family FGF60_RS17235 ENOG4105CHF Glutathione S-transferase FGF60_RS17240 ENOG4105KAF membrAne FGF60_RS17245 ENOG4105CWB LysR family transcriptional Regulator FGF60_RS17250 ENOG4108CNN domain protein FGF60_RS17255 ENOG4106D80 Uncharacterized protein YhaL FGF60_RS17265 ENOG4105C44 Serine transporter FGF60_RS17270 ENOG4105EJQ L-serine dehydratase FGF60_RS17275 ENOG4105C6N Formate acetyltransferase FGF60_RS17290 ENOG4105C7B Threonine dehydratase FGF60_RS17295 ENOG410811B TRANSCRIPTIONal FGF60_RS17305 ENOG4105BZW Glycerate kinase FGF60_RS17310 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FGF60_RS17320 ENOG4105CTX dehydratase FGF60_RS17325 ENOG4107UEK pfkb domain protein FGF60_RS17330 ENOG4105MVE transcriptional regulator FGF60_RS17335 ENOG4105D2N Aldolase FGF60_RS17340 ENOG4105DE4 1-phosphofructokinase FGF60_RS17345 ENOG4105DM4 PTS System FGF60_RS17350 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FGF60_RS17360 ENOG41082GB PTS system galactitol-specific transporter subunit IIA FGF60_RS17365 ENOG41090UW PTS System FGF60_RS17370 ENOG4105DT3 PTS system, galactitol-specific IIc component FGF60_RS17375 ENOG4107WTH Galactitol-1-phosphate dehydrogenase FGF60_RS17385 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FGF60_RS17405 ENOG4105W4M Transport-associated protein FGF60_RS17410 ENOG4105K4T epimerase FGF60_RS17415 ENOG4107R7Y intracellular protease Pfpi family FGF60_RS17430 ENOG4108YYD acetyltransferase FGF60_RS17450 ENOG4105DEN Luciferase family FGF60_RS17455 ENOG4105F7V ErfK ybiS ycfS ynhG family protein FGF60_RS17465 ENOG4105CIC tryptophan-specific transport protein FGF60_RS17470 ENOG4105C1J atp-dependent rna helicase FGF60_RS17510 ENOG4105CHV Transcription elongation factor NusA FGF60_RS17515 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) FGF60_RS17540 ENOG4105NTZ Preprotein translocase subunit SecG FGF60_RS17550 ENOG4105EEI dihydropteroate synthase FGF60_RS17555 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FGF60_RS17565 ENOG4105HBR Rna-binding protein FGF60_RS17570 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FGF60_RS17575 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase FGF60_RS17580 ENOG4108RS6 transposase FGF60_RS17590 ENOG4105QYV Membrane FGF60_RS17595 ENOG4105K46 50S ribosomal protein l27 FGF60_RS17605 ENOG4105EAH synthase FGF60_RS17610 ENOG4105HVQ Regulatory factor of maltose metabolism FGF60_RS17620 ENOG4105VFK BolA family FGF60_RS17625 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane FGF60_RS17630 ENOG4105E3I toluene tolerance FGF60_RS17635 ENOG4107PE3 Mammalian cell entry related domain protein FGF60_RS17640 ENOG4105CY3 ABC transporter, permease FGF60_RS17645 ENOG4105DHJ ABC, transporter FGF60_RS17650 ENOG4105FEU K -dependent Na -Ca exchanger FGF60_RS17655 ENOG4105C2X Arabinose 5-phosphate isomerase FGF60_RS17660 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase FGF60_RS17665 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) FGF60_RS17670 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FGF60_RS17675 ENOG4108IUZ ABC transporter FGF60_RS17680 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FGF60_RS17685 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA FGF60_RS17690 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN FGF60_RS17700 ENOG41080Z8 PHOSPHOCARRIER protein FGF60_RS17705 ENOG4108NIH transferase activity, transferring phosphorus-containing groups FGF60_RS17715 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain FGF60_RS17720 ENOG4105BZU Histidine kinase FGF60_RS17725 ENOG4105N5T Radical SAM Protein FGF60_RS17730 ENOG4105CBC glutamate synthase FGF60_RS17735 ENOG4105BZ8 glutamate synthase FGF60_RS17740 ENOG4105DFS Conserved Protein FGF60_RS17745 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin FGF60_RS17750 ENOG4105DZC cytosine deaminase FGF60_RS17755 ENOG4108R66 Conserved Protein FGF60_RS17765 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) FGF60_RS17785 ENOG4105KB2 stringent starvation protein b FGF60_RS17790 ENOG4107MKT Stringent starvation protein a FGF60_RS17815 ENOG4105D6Z AFG1 family ATPase FGF60_RS17820 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III FGF60_RS17825 ENOG4105C0H protease FGF60_RS17835 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FGF60_RS17840 ENOG4105D9Q decarboxylase (Beta subunit) FGF60_RS17845 ENOG4107QSA Oxaloacetate decarboxylase FGF60_RS17855 ENOG4107GFK fumarate FGF60_RS17860 ENOG4106DSS Tartrate dehydratase subunit alpha FGF60_RS17865 ENOG4105C8P )-transporter FGF60_RS17890 ENOG4105RID UPF0379 protein yhcN FGF60_RS17895 ENOG4105RID UPF0379 protein yhcN FGF60_RS17900 ENOG4105UNR (Barnase) inhibitor FGF60_RS17915 ENOG4105ZQC membrane protein AaeX FGF60_RS17920 ENOG4105CR8 Transcriptional regulator FGF60_RS17925 ENOG4105D1U peptidase U62 modulator of DNA gyrase FGF60_RS17930 ENOG4105QD6 exported protein FGF60_RS17935 ENOG4105C03 ribonuclease FGF60_RS17940 ENOG4108Z03 MAF-like protein FGF60_RS17945 ENOG4105VQ7 Rod shape-determining protein MreD FGF60_RS17950 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FGF60_RS17960 ENOG41062P1 Diguanylate cyclase phosphodiesterase FGF60_RS17965 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family FGF60_RS17985 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FGF60_RS17990 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FGF60_RS17995 ENOG4105RG0 Membrane FGF60_RS18000 ENOG4108IA2 Sodium pantothenate symporter FGF60_RS18010 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FGF60_RS18020 ENOG4105CEC DNA methylase N-4 N-6 FGF60_RS18025 ENOG41061ME transport protein FGF60_RS18030 ENOG4105BZU Histidine kinase FGF60_RS18035 ENOG4108XG4 DNA-binding transcriptional regulator FGF60_RS18040 ENOG4105C1P efflux transporter, rnd family, mfp subunit FGF60_RS18045 ENOG4105BZS acriflavin resistance protein FGF60_RS18050 ENOG4105XCM membrane LIPOPROTEIN FGF60_RS18085 ENOG4108Z0R Transferase FGF60_RS18090 ENOG4105SG3 Protein of unknown function (DUF1488) FGF60_RS18095 ENOG4105E2X shikimate dehydrogenase FGF60_RS18100 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FGF60_RS18105 ENOG4108WI1 Dna topoisomerase FGF60_RS18115 ENOG4105C79 DNA protecting protein DprA FGF60_RS18130 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FGF60_RS18135 ENOG4105C1A potassium transporter peripheral membrane FGF60_RS18140 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) FGF60_RS18145 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system FGF60_RS18150 ENOG4105W1Y Transcriptional regulator FGF60_RS18155 ENOG4105VTS DnaJ-like, subfamily C FGF60_RS18170 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FGF60_RS18185 ENOG41067V7 50S ribosomal protein L36 FGF60_RS18190 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FGF60_RS18200 ENOG4105VPB 50S ribosomal protein L30 FGF60_RS18210 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FGF60_RS18235 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FGF60_RS18245 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FGF60_RS18250 ENOG41083MP 50s ribosomal protein l29 FGF60_RS18270 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FGF60_RS18300 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) FGF60_RS18305 ENOG4108UQY Iron-storage protein FGF60_RS18310 ENOG4105W53 bacterioferritin-associated ferredoxin FGF60_RS18315 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FGF60_RS18325 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FGF60_RS18335 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) FGF60_RS18340 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) FGF60_RS18350 ENOG4105WWK YheO domain protein FGF60_RS18355 ENOG4108V1T peptidylprolyl cis-trans isomerase FGF60_RS18360 ENOG4105VRX Protein slyX homolog FGF60_RS18365 ENOG4108YZY peptidylprolyl cis-trans isomerase FGF60_RS18370 ENOG4105VKU nucleicacid-binding protein FGF60_RS18385 ENOG4105C5H ABC transporter FGF60_RS18390 ENOG4108K70 Transcriptional regulator FGF60_RS18395 ENOG4105N0V mono-oxygenase ydhR FGF60_RS18400 ENOG4105DNZ Alpha Beta Hydrolase FGF60_RS18410 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) FGF60_RS18415 ENOG4108UKZ OsmC family FGF60_RS18420 ENOG4107RYR Transcriptional regulator, Crp Fnr family FGF60_RS18425 ENOG410613R integral membrane protein, YccS YhfK family FGF60_RS18430 ENOG4105C8Y Acetylornithine aminotransferase FGF60_RS18435 ENOG4105DDQ anthranilate synthase FGF60_RS18440 ENOG4105MZU cell filamentation protein FGF60_RS18445 ENOG4106195 uncharacterized protein yhfG FGF60_RS18450 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FGF60_RS18460 ENOG4107QZF nitrite reductase NADPH large subunit FGF60_RS18465 ENOG4105WZK nitrite reductase NADPH small subunit FGF60_RS18470 ENOG4107V9H nitrite transporter FGF60_RS18475 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FGF60_RS18485 ENOG4108RS6 transposase FGF60_RS18490 ENOG4105VYH FGF60_RS18495 ENOG4105C31 Tryptophanyl-tRNA synthetase FGF60_RS18500 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FGF60_RS18505 ENOG4105DJV ribulose-phosphate 3-epimerase FGF60_RS18510 ENOG4105DFE Dna adenine methylase FGF60_RS18515 ENOG4105EGB membrane protein DamX FGF60_RS18520 ENOG4105D49 3-dehydroquinate synthase FGF60_RS18530 ENOG4105E4G Type IV pilus FGF60_RS18535 ENOG4105ITY Required for the use of extracellular DNA as a nutrient FGF60_RS18540 ENOG4105XPX DNA utilization protein HofO FGF60_RS18545 ENOG41065NF Fimbrial assembly family protein FGF60_RS18550 ENOG4108U1Q Pilus assembly protein FGF60_RS18555 ENOG4108JQC penicillin-binding protein 1A FGF60_RS18560 ENOG4107RK2 ADP-ribose diphosphatase NudE FGF60_RS18570 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FGF60_RS18575 ENOG4105VEJ Heat shock protein FGF60_RS18580 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FGF60_RS18585 ENOG4108MAJ Membrane FGF60_RS18595 ENOG4105E0F Histidine kinase FGF60_RS18605 ENOG4108RRZ Transcription elongation factor GreB FGF60_RS18610 ENOG4105BZM domain protein FGF60_RS18615 ENOG4105XFK Ferrous iron transport protein A FGF60_RS18620 ENOG4105CE1 Ferrous iron transport protein b FGF60_RS18630 ENOG4105DNE Transposase FGF60_RS18640 ENOG4105MJ2 Competence protein FGF60_RS18650 ENOG4105C6Z Gluconate FGF60_RS18655 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) FGF60_RS18660 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FGF60_RS18665 ENOG41061ZR Transcriptional regulator FGF60_RS18670 ENOG4105VXN addiction module toxin, RelE StbE family FGF60_RS18680 ENOG4105CKX Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP FGF60_RS18685 ENOG4105E0Y RtcB Protein FGF60_RS18695 ENOG4105CYB regulatoR FGF60_RS18700 ENOG4105E98 transcriptional regulator DeoR family FGF60_RS18715 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FGF60_RS18730 ENOG4105DCT glycerol dehydrogenase FGF60_RS18740 ENOG4105C01 Dihydroxy-acid dehydratase FGF60_RS18745 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FGF60_RS18750 ENOG4107HP6 Transcriptional regulator FGF60_RS18755 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FGF60_RS18775 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) FGF60_RS18780 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FGF60_RS18785 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FGF60_RS18790 ENOG4105C6Z Gluconate FGF60_RS18795 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FGF60_RS18800 ENOG4105DIQ Transcriptional regulator FGF60_RS18805 ENOG4105C2I pirin domain protein FGF60_RS18810 ENOG4105D9R oxidoreductase FGF60_RS18815 ENOG4105WCN acetyltransferase FGF60_RS18820 ENOG4108RVA ribokinase FGF60_RS18835 ENOG41080QX K07048 phosphotriesterase-related protein FGF60_RS18840 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FGF60_RS18845 ENOG4105WC8 Conserved Protein FGF60_RS18850 ENOG4107T6V glycerophosphoryl diester phosphodiesterase FGF60_RS18855 ENOG4108IJ9 (ABC) transporter FGF60_RS18865 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component FGF60_RS18870 ENOG4105BZ7 extracellular solute-binding protein family 1 FGF60_RS18880 ENOG41060M8 Pfam:PhdYeFM FGF60_RS18885 ENOG4108IV0 ABC, transporter FGF60_RS18890 ENOG4105C0Z ABC transporter FGF60_RS18895 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FGF60_RS18900 ENOG4105C32 Amino acid ABC transporter (Permease) FGF60_RS18905 ENOG4105CP9 extracellular ligand-binding receptor FGF60_RS18910 ENOG4105U59 -acetyltransferase FGF60_RS18920 ENOG4105CP9 extracellular ligand-binding receptor FGF60_RS18930 ENOG4105CRP Part of the ABC transporter FtsEX involved in FGF60_RS18935 ENOG4105CAK Cell division ATP-binding protein ftsE FGF60_RS18940 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FGF60_RS18945 ENOG4106H78 methyltransferase FGF60_RS18950 ENOG4105MG3 Membrane FGF60_RS18960 ENOG4107FS9 Membrane FGF60_RS18970 ENOG4105C8Q Methyl-accepting chemotaxis FGF60_RS18980 ENOG4105EX9 Membrane FGF60_RS18985 ENOG4108W1V Lipoprotein FGF60_RS18995 ENOG4105DSF transport protein FGF60_RS19000 ENOG4107YAK holo-(acyl carrier protein) synthase 2 FGF60_RS19010 ENOG4105CMI transporter FGF60_RS19015 ENOG4105CJ1 ABC, transporter FGF60_RS19020 ENOG4105D0S secretion protein (HlyD FGF60_RS19025 ENOG4105CBX hi0933 family FGF60_RS19030 ENOG4105CJ3 phosphate transporter FGF60_RS19040 ENOG4108M6U Universal stress protein A FGF60_RS19045 ENOG4105DUX Transporter FGF60_RS19050 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) FGF60_RS19055 ENOG4105DGW oligopeptidase A FGF60_RS19060 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FGF60_RS19065 ENOG4105D6S protein involved in catabolism of external DNA FGF60_RS19070 ENOG4105DC8 reductase FGF60_RS19080 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FGF60_RS19085 ENOG4108KPW sugar kinase FGF60_RS19090 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine FGF60_RS19095 ENOG4105FDP GntR family transcriptional regulator FGF60_RS19115 ENOG4106S2D Transcriptional regulator FGF60_RS19120 ENOG4105CBN LysR family transcriptional regulator FGF60_RS19125 ENOG4107H3J ribonuclease FGF60_RS19130 ENOG4105CSH Transporter FGF60_RS19135 ENOG41066T0 asmA family FGF60_RS19140 ENOG4105CMB EAL domain-containing protein FGF60_RS19145 ENOG4107SS6 2-dehydro-3-deoxygluconokinase FGF60_RS19150 ENOG4105CS0 peptidase FGF60_RS19160 ENOG4105BZU Histidine kinase FGF60_RS19165 ENOG4105EJG cellulose synthase FGF60_RS19170 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) FGF60_RS19175 ENOG4107EEX Cellulose synthase regulator protein FGF60_RS19180 ENOG4107QZ7 Cellulose synthase catalytic subunit FGF60_RS19185 ENOG4105UTS cellulose synthase operon protein YhjQ FGF60_RS19190 ENOG410661M cytoplasmic protein FGF60_RS19200 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT FGF60_RS19205 ENOG4105D1V cellulose synthase operon protein YhjU FGF60_RS19220 ENOG4105C44 Serine transporter FGF60_RS19225 ENOG4108JQ7 (ABC) transporter FGF60_RS19230 ENOG4105C3U ABC transporter FGF60_RS19235 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FGF60_RS19240 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FGF60_RS19245 ENOG4105DEF Extracellular solute-binding protein, family 5 FGF60_RS19275 ENOG4105DIJ Phosphoethanolamine transferase FGF60_RS19280 ENOG4106UCC Fimbrial protein FGF60_RS19285 ENOG4105MHR Fimbrial protein FGF60_RS19290 ENOG4105CW0 outer membrane usher protein FGF60_RS19295 ENOG4108VCD Chaperone FGF60_RS19300 ENOG4108RS6 transposase FGF60_RS19305 ENOG4106EAR Fimbrial protein FGF60_RS19310 ENOG4105EAX Putative lipase FGF60_RS19315 ENOG4108R3E Dna-3-methyladenine glycosylase i FGF60_RS19320 ENOG4105HNP -acetyltransferase FGF60_RS19325 ENOG4107QY8 reductase FGF60_RS19330 ENOG4108ZG0 Ompa motb domain protein FGF60_RS19340 ENOG4106JH6 (LipO)protein FGF60_RS19345 ENOG4105MVF Transcriptional regulator FGF60_RS19375 ENOG4105DQ6 Transposase FGF60_RS19400 ENOG4105MEV Acyl-transferase FGF60_RS19405 ENOG410688U Inner membrane protein yiaB FGF60_RS19410 ENOG4105CMG Carbohydrate kinase FGF60_RS19420 ENOG4105T16 Transcriptional regulator (AraC family) FGF60_RS19425 ENOG4108UR8 BAX protein FGF60_RS19430 ENOG4107T9C Alpha amylase catalytic region FGF60_RS19435 ENOG4105JKW Valine--pyruvate aminotransferase FGF60_RS19440 ENOG4108XIB electron transport protein ysaA FGF60_RS19445 ENOG4105J4Q Transcriptional regulator FGF60_RS19450 ENOG4105DG4 malate L-lactate dehydrogenase FGF60_RS19455 ENOG4108R66 Conserved Protein FGF60_RS19460 ENOG4108M5W FGF60_RS19465 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter FGF60_RS19470 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FGF60_RS19475 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FGF60_RS19480 ENOG4105CMG Carbohydrate kinase FGF60_RS19485 ENOG4105H6Q decarboxylase FGF60_RS19490 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase FGF60_RS19495 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FGF60_RS19510 ENOG4105C26 Dehydrogenase FGF60_RS19515 ENOG41066F8 ROK family FGF60_RS19520 ENOG4105EM7 Selenocysteine-specific translation elongation factor FGF60_RS19530 ENOG4108U78 Glutathione S-transferase FGF60_RS19535 ENOG4105CTS PTS system mannitol-specific FGF60_RS19545 ENOG4105E61 Mannitol repressor protein FGF60_RS19555 ENOG4108YYI Protein of unknown function (DUF2810) FGF60_RS19560 ENOG4108WY4 inner membrane lipoprotein FGF60_RS19565 ENOG4105EUR Domain-Containing protein FGF60_RS19570 ENOG4105DAA L-lactate FGF60_RS19575 ENOG41073TP transcriptional regulator FGF60_RS19585 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FGF60_RS19590 ENOG4105ETE Transcriptional regulator (LacI family FGF60_RS19595 ENOG4105DIA mandelate racemase muconate lactonizing FGF60_RS19600 ENOG4105DJB Major Facilitator Superfamily FGF60_RS19605 ENOG4105D7W serine acetyltransferase FGF60_RS19610 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase FGF60_RS19615 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) FGF60_RS19620 ENOG4105VW4 glutaredoxin 3 FGF60_RS19625 ENOG4107YZP Rhodanese domain protein FGF60_RS19635 ENOG41063SB peptidase FGF60_RS19640 ENOG4105PXI polysaccharide deacetylase FGF60_RS19645 ENOG4105K64 Glycosyl transferase, family 2 FGF60_RS19655 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FGF60_RS19665 ENOG4105XA0 heptosyltransferase ii FGF60_RS19670 ENOG4105D16 lipopolysaccharide heptosyltransferase i FGF60_RS19675 ENOG4108FRV O-antigen ligase FGF60_RS19680 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase FGF60_RS19685 ENOG4108QD8 lipopolysaccharide core biosynthesis protein FGF60_RS19690 ENOG4108PDR lipopolysaccharide core biosynthesis protein FGF60_RS19695 ENOG4105X1N Glycosyl transferase family 8 FGF60_RS19700 ENOG4106AH0 Glycosyl Transferase FGF60_RS19705 ENOG4107XU6 Glycosyl transferase (Group 1 FGF60_RS19720 ENOG4107543 (lipo)polysaccharide FGF60_RS19725 ENOG4107RJ7 Glycosyl transferase (Group 1 FGF60_RS19730 ENOG4105DKP glycosyl transferase, family 9 FGF60_RS19735 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FGF60_RS19740 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FGF60_RS19765 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FGF60_RS19785 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) FGF60_RS19790 ENOG4105DSJ YicC domain protein FGF60_RS19805 ENOG4105EN6 Membrane FGF60_RS19810 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) FGF60_RS19815 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FGF60_RS19825 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FGF60_RS19830 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase FGF60_RS19835 ENOG4105CB5 ATP-dependent DNA helicase recG FGF60_RS19845 ENOG4105D6U Sodium Glutamate Symporter FGF60_RS19850 ENOG4105C2W permease FGF60_RS19855 ENOG4105JV1 AsmA family FGF60_RS19860 ENOG4105CJQ hydrolase, family 31 FGF60_RS19865 ENOG4105CT4 transporter FGF60_RS19885 ENOG4107WZZ SMC domain protein FGF60_RS19910 ENOG4105ISV protein with bipartite regulator domain FGF60_RS19920 ENOG4105FV3 FGF60_RS19925 ENOG4108TC1 Transcriptional regulator FGF60_RS19935 ENOG4105CHJ isochorismatase hydrolase FGF60_RS19950 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FGF60_RS19960 ENOG4108UZ3 Transporter FGF60_RS19965 ENOG4105DNE Transposase FGF60_RS19980 ENOG4105F3R pts system mannose fructose sorbose family iid FGF60_RS19985 ENOG4105ETZ PTS System FGF60_RS19990 ENOG4105DAS pts system FGF60_RS20005 ENOG4105T8A Uncharacterized protein YicS FGF60_RS20010 ENOG4105CS2 ec 3.2.1.21 FGF60_RS20035 ENOG4105D2N Aldolase FGF60_RS20045 ENOG4105DT3 PTS system, galactitol-specific IIc component FGF60_RS20050 ENOG41090UW PTS System FGF60_RS20065 ENOG4108SAJ Protein of unknown function (DUF1198) FGF60_RS20070 ENOG4105CXY transporter FGF60_RS20075 ENOG4105CXY transporter FGF60_RS20080 ENOG4105BZU Histidine kinase FGF60_RS20085 ENOG4108KX4 response regulator FGF60_RS20095 ENOG4105EDR glucose galactose transporter FGF60_RS20105 ENOG4107FB0 transcriptional regulator DeoR family FGF60_RS20110 ENOG4105M71 acetolactate synthase 1 regulatory subunit FGF60_RS20115 ENOG4105C7K acetolactate synthase FGF60_RS20140 ENOG4105E5M Multidrug resistance protein D FGF60_RS20150 ENOG4105W8I Transcriptional regulator FGF60_RS20160 ENOG4105BZC d-serine deaminase FGF60_RS20165 ENOG4105J13 transcriptional regulator FGF60_RS20170 ENOG4105JP4 Inner membrane protein yidG FGF60_RS20175 ENOG4105VG5 Membrane FGF60_RS20195 ENOG4105R2A (LipO)protein FGF60_RS20200 ENOG4105D99 atp gtp-binding protein FGF60_RS20205 ENOG4105KWW Biogenesis protein FGF60_RS20210 ENOG4107QX9 Thiol disulfide interChange protein FGF60_RS20215 ENOG4105DA4 cytochrome c-type biogenesis protein FGF60_RS20220 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) FGF60_RS20225 ENOG4105X3C heme exporter protein FGF60_RS20235 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) FGF60_RS20245 ENOG4105CA0 peroxidase FGF60_RS20255 ENOG4108EM1 reductase FGF60_RS20260 ENOG4105CUW cytochrome C-TYPE protein FGF60_RS20265 ENOG4106WF9 DNA-binding transcriptional regulator TorR FGF60_RS20270 ENOG4108SV3 Tmao reductase system periplasmic protein tort FGF60_RS20275 ENOG4105BZU Histidine kinase FGF60_RS20280 ENOG4105DJB Major Facilitator Superfamily FGF60_RS20290 ENOG4108RTU Aldolase FGF60_RS20295 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 FGF60_RS20300 ENOG4105EMF GntR family transcriptional regulator FGF60_RS20305 ENOG410667J hydrolase FGF60_RS20310 ENOG4105DJB Major Facilitator Superfamily FGF60_RS20315 ENOG4105CXK mandelate racemase muconate lactonizing FGF60_RS20325 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FGF60_RS20335 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FGF60_RS20345 ENOG4105VG0 50S ribosomal protein l34 FGF60_RS20360 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FGF60_RS20365 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FGF60_RS20380 ENOG4107RRE RNA-directed DNA polymerase FGF60_RS20385 ENOG4105CNH Multidrug resistance protein MdtL FGF60_RS20390 ENOG4105G2Y Transcriptional regulator FGF60_RS20395 ENOG4105E8Q phosphopantetheinyl transferase FGF60_RS20400 ENOG4108YYH Nadph-dependent fmn reductase FGF60_RS20405 ENOG4105C7N Xanthine uracil vitamin C permease FGF60_RS20410 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 FGF60_RS20420 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FGF60_RS20425 ENOG4105E2Z phosphate ABC transporter (Permease FGF60_RS20430 ENOG4105C8U phosphate abc transporter FGF60_RS20435 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) FGF60_RS20440 ENOG4105DM4 PTS System FGF60_RS20445 ENOG4105F9E Shikimate 5-dehydrogenase FGF60_RS20450 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FGF60_RS20455 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FGF60_RS20470 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FGF60_RS20475 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) FGF60_RS20495 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FGF60_RS20510 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation FGF60_RS20525 ENOG4105QTB Flavodoxin FGF60_RS20530 ENOG4108VVK transcriptional Regulator, AsnC FGF60_RS20535 ENOG4105CU9 asparagine synthetase A FGF60_RS20545 ENOG4107R4Q Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity) FGF60_RS20560 ENOG4105C2J ABC transporter FGF60_RS20565 ENOG4105CNN ABC, transporter FGF60_RS20570 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FGF60_RS20575 ENOG4108RVA ribokinase FGF60_RS20580 ENOG4105ETE Transcriptional regulator (LacI family FGF60_RS20585 ENOG4105C0R drug resistance transporter emrb qaca subfamily FGF60_RS20590 ENOG4107EJG GntR family transcriptional regulator FGF60_RS20635 ENOG4105C0P Mg chelatase subunit ChlI FGF60_RS20650 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit FGF60_RS20655 ENOG4105CM2 brancheD-chain amino acid aminotransferase FGF60_RS20665 ENOG4105C7B Threonine dehydratase FGF60_RS20680 ENOG4105EMY transcriptional regulator FGF60_RS20685 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FGF60_RS20690 ENOG4105KQ5 peptidylprolyl cis-trans isomerase FGF60_RS20700 ENOG4106Z1T Nicotinamide Mononucleotide Transporter FGF60_RS20705 ENOG4105C4R Atp-dependent dna helicase FGF60_RS20730 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FGF60_RS20735 ENOG4105ESV Glycosyl transferase, family 4 FGF60_RS20740 ENOG4105SFE lipopolysaccharide biosynthesis protein FGF60_RS20745 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FGF60_RS20750 ENOG4108IJ1 Dehydrogenase FGF60_RS20755 ENOG4105C1B dTDP-glucose 4-6-dehydratase FGF60_RS20760 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FGF60_RS20760 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FGF60_RS20765 ENOG4108WJ1 acetyltransferase FGF60_RS20770 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FGF60_RS20775 ENOG4105EGZ biosynthesis protein FGF60_RS20780 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) FGF60_RS20785 ENOG4105DAD Could be involved in ECA polysaccharide chain elongation (By similarity) FGF60_RS20795 ENOG4105C85 amino acid FGF60_RS20820 ENOG410601J HemY protein FGF60_RS20825 ENOG4105ECF c-methyltransferase FGF60_RS20830 ENOG41076E6 Uroporphyrinogen-III Synthase FGF60_RS20840 ENOG4107T0K Adenylate cyclase FGF60_RS20860 ENOG4105XQ6 frataxin-like protein FGF60_RS20875 ENOG4105S7Z (LipO)protein FGF60_RS20885 ENOG4105CT0 Protein of unknown function, DUF484 FGF60_RS20890 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FGF60_RS20895 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant FGF60_RS20900 ENOG4105C4R Atp-dependent dna helicase FGF60_RS20905 ENOG4107QUT magnesium and cobalt transport protein CorA FGF60_RS20910 ENOG4105NRM Membrane FGF60_RS20915 ENOG4106WR8 Inner membrane protein YigG FGF60_RS20920 ENOG4105FR1 rard protein FGF60_RS20925 ENOG4108VUY thioesterase Superfamily protein FGF60_RS20930 ENOG4105HDD phospholipase FGF60_RS20935 ENOG4105C9U ATP-dependent DNA helicase RecQ FGF60_RS20940 ENOG4105CCF Lysine exporter protein (Lyse ygga) FGF60_RS20945 ENOG410829K Lysine exporter protein (Lyse ygga) FGF60_RS20950 ENOG4108EUD Lysophospholipase FGF60_RS20955 ENOG4105DQF Hydrolase FGF60_RS20960 ENOG4105EMK carboxylate amino acid amine transporter FGF60_RS20965 ENOG4105DZ2 Transcriptional regulator FGF60_RS20980 ENOG4105C4X radical SAM domain protein FGF60_RS20985 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) FGF60_RS20990 ENOG4107SXA Phosphorylase FGF60_RS20995 ENOG4105CGY Dna recombination protein FGF60_RS21005 ENOG4105JC1 sterol-binding domain protein FGF60_RS21015 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FGF60_RS21020 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) FGF60_RS21025 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FGF60_RS21030 ENOG4105F8V Hydrolase, tatD family FGF60_RS21035 ENOG4105MDZ Transcriptional activator rfaH FGF60_RS21040 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FGF60_RS21045 ENOG4107QK7 reductase FGF60_RS21055 ENOG4105CHU acetyl-coa acetyltransferase FGF60_RS21060 ENOG4108EIM Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities (By similarity) FGF60_RS21070 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FGF60_RS21075 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FGF60_RS21080 ENOG4108RR8 protoporphyrinogen oxidase FGF60_RS21110 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b FGF60_RS21115 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FGF60_RS21120 ENOG4105PC1 Conserved Protein FGF60_RS21125 ENOG4105E27 serine threonine protein kinase FGF60_RS21130 ENOG4108Z33 Thiol disulfide Interchange Protein FGF60_RS21135 ENOG4106HNH Acyl-transferase FGF60_RS21140 ENOG4105C2M dna polymerase I FGF60_RS21160 ENOG4105D4P Coproporphyrinogen iii oxidase FGF60_RS21165 ENOG4106FIY FGF60_RS21170 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FGF60_RS21175 ENOG4105CUX Signal transduction histidine kinase FGF60_RS21180 ENOG4105C5F glutamine synthetase FGF60_RS21185 ENOG4105CI3 gtp-binding protein typa FGF60_RS21190 ENOG4108K4B hydrolase FGF60_RS21220 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is FGF60_RS21225 ENOG4105CT4 transporter FGF60_RS21230 ENOG4105CT4 transporter FGF60_RS21235 ENOG4105CJQ hydrolase, family 31 FGF60_RS21240 ENOG4107WI4 Aldose-1-epimerase FGF60_RS21245 ENOG4107QKS N-acylglucosamine 2-epimerase FGF60_RS21250 ENOG4105D2M Aldolase FGF60_RS21255 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FGF60_RS21260 ENOG4108MGF sugar kinase FGF60_RS21265 ENOG4105E98 transcriptional regulator DeoR family FGF60_RS21270 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 FGF60_RS21275 ENOG4107S2Z UPF0761 membrane protein FGF60_RS21285 ENOG4105SUU thioesterase domain FGF60_RS21290 ENOG4108Z3N Transcriptional regulator FGF60_RS21295 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) FGF60_RS21305 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system FGF60_RS21320 ENOG4108MG3 formate dehydrogenase FGF60_RS21325 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FGF60_RS21340 ENOG4108V87 frv operon regulatory protein FGF60_RS21345 ENOG4108V87 frv operon regulatory protein FGF60_RS21355 ENOG4108UMN azlc family FGF60_RS21370 ENOG4105C0A alcohol dehydrogenase FGF60_RS21380 ENOG4105DKG l-rhamnose isomerase FGF60_RS21385 ENOG4105DET Rhamnulokinase FGF60_RS21405 ENOG4108QGT oligogalacturonate-specific porin FGF60_RS21410 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FGF60_RS21415 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter FGF60_RS21420 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FGF60_RS21425 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FGF60_RS21430 ENOG4108RPX mosc domain containing protein FGF60_RS21440 ENOG4105E0F Histidine kinase FGF60_RS21445 ENOG4105E3W Two component transcriptional regulator (Winged helix family FGF60_RS21450 ENOG4105FMW periplasmic FGF60_RS21460 ENOG4105CTQ phosphohexokinase FGF60_RS21465 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FGF60_RS21475 ENOG4105CT4 transporter FGF60_RS21480 ENOG4105D7K pfkb domain protein FGF60_RS21500 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) FGF60_RS21510 ENOG4107RYS Autoinducer-2 (AI-2) kinase FGF60_RS21515 ENOG4105DKT Transcriptional regulator FGF60_RS21520 ENOG4105C2J ABC transporter FGF60_RS21535 ENOG4105D4B ABC, transporter FGF60_RS21545 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound FGF60_RS21560 ENOG4105EBK exported protein FGF60_RS21565 ENOG4108VTS Membrane FGF60_RS21570 ENOG4105DP0 ferredoxin-NADP reductase FGF60_RS21575 ENOG4105CBT Fructose-1,6-bisphosphatase FGF60_RS21580 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FGF60_RS21585 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FGF60_RS21600 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FGF60_RS21615 ENOG41063M6 Cell Division Protein FGF60_RS21620 ENOG4105ETE Transcriptional regulator (LacI family FGF60_RS21625 ENOG4105C25 Primosomal protein n' FGF60_RS21640 ENOG4108MR7 Arylsulfotransferase FGF60_RS21650 ENOG4105C28 cystathionine FGF60_RS21655 ENOG4105CFH Aspartokinase FGF60_RS21660 ENOG4105D64 Mechanosensitive ion channel FGF60_RS21675 ENOG4105CGH 5'-nucleotidase FGF60_RS21680 ENOG4105SYT Methylenetetrahydrofolate reductase FGF60_RS21690 ENOG4108XC3 NADH ubiquinone oxidoreductase FGF60_RS21695 ENOG4105DCT glycerol dehydrogenase FGF60_RS21705 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FGF60_RS21710 ENOG4105DM4 PTS System FGF60_RS21715 ENOG4108YRF PTS System FGF60_RS21725 ENOG4108AHH pyruvate formate lyase II activase FGF60_RS21730 ENOG4108XCZ PTS System FGF60_RS21735 ENOG4106R3P AraC family transcriptional regulator FGF60_RS21740 ENOG4105DIJ Phosphoethanolamine transferase FGF60_RS21750 ENOG4105CWC Acetylornithine deacetylase FGF60_RS21755 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FGF60_RS21765 ENOG4105CH7 arginosuccinase FGF60_RS21770 ENOG4105C5Q Transcriptional regulator FGF60_RS21785 ENOG4108Y73 Membrane FGF60_RS21795 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) FGF60_RS21830 ENOG4105D4A Cell wall formation (By similarity) FGF60_RS21835 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase FGF60_RS21870 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FGF60_RS21875 ENOG4105PM1 preprotein translocase subunit SecE FGF60_RS21880 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FGF60_RS21895 ENOG4108VZM 50s ribosomal protein L10 FGF60_RS21900 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FGF60_RS21905 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FGF60_RS21910 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FGF60_RS21940 ENOG4105D41 biosynthesis protein thiH FGF60_RS21945 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) FGF60_RS21950 ENOG4105WHD thiamine biosynthesis protein ThiS FGF60_RS21955 ENOG4105D06 uba thif-type nad fad binding protein FGF60_RS21960 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FGF60_RS21975 ENOG4105E09 nadh pyrophosphatase FGF60_RS21990 ENOG4105R2J Conserved Protein FGF60_RS21995 ENOG4105K70 DNA-binding protein FGF60_RS22000 ENOG4108T8B Protein of unknown function (DUF1481) FGF60_RS22010 ENOG4105BZU Histidine kinase FGF60_RS22015 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FGF60_RS22020 ENOG4105C12 Phosphoribosylglycinamide synthetase FGF60_RS22025 ENOG4105DC1 bifunctional purine biosynthesis protein purh FGF60_RS22050 ENOG4105K5X acetyltransferase FGF60_RS22060 ENOG4107QP3 malate synthase g FGF60_RS22065 ENOG4108I9X Isocitrate lyase FGF60_RS22080 ENOG41069M3 Transcriptional regulator FGF60_RS22085 ENOG4105C3R Methionine synthase FGF60_RS22090 ENOG4105EAM Na Pi-cotransporter FGF60_RS22095 ENOG4105EQ6 Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity) FGF60_RS22105 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FGF60_RS22115 ENOG4108ZR5 Conserved Protein FGF60_RS22120 ENOG4105C09 Bile acid FGF60_RS22145 ENOG4108X9F tail fiber protein FGF60_RS22170 ENOG4105CKK Glycosyl transferase, family 2 FGF60_RS22175 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) FGF60_RS22255 ENOG4105CFH Aspartokinase FGF60_RS22270 ENOG4108MDC (LipO)protein FGF60_RS22275 ENOG4108Q9C Periplasmic Protein FGF60_RS22280 ENOG4105E3R (LipO)protein FGF60_RS22290 ENOG4105EG2 ABC transporter, permease FGF60_RS22295 ENOG4105D56 permease protein FGF60_RS22300 ENOG4107FKK extracellular solute-binding protein family 1 FGF60_RS22305 ENOG4108IJ9 (ABC) transporter FGF60_RS22315 ENOG4107W52 maltose operon periplasmic protein FGF60_RS22335 ENOG41080IJ Diacylglycerol kinase FGF60_RS22340 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FGF60_RS22345 ENOG4107R73 Mate efflux family protein FGF60_RS22355 ENOG4105VDW Csbd family FGF60_RS22360 ENOG4105MYN Zinc uptake regulation protein FGF60_RS22370 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FGF60_RS22375 ENOG4105P4Z Phage shock protein G FGF60_RS22380 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FGF60_RS22385 ENOG4105CDU Replicative dna helicase FGF60_RS22390 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FGF60_RS22395 ENOG4105CGF Aromatic amino acid aminotransferase FGF60_RS22400 ENOG4105F0S class B acid phosphatase FGF60_RS22405 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FGF60_RS22410 ENOG4105MSB protein, conserved in bacteria FGF60_RS22425 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FGF60_RS22430 ENOG4108UUM single-stranded DNA-binding protein FGF60_RS22480 ENOG4105PMV Membrane FGF60_RS22485 ENOG4108M8H domain protein FGF60_RS22490 ENOG4108W3Q Transcriptional regulator FGF60_RS22495 ENOG4108Z4X TRANSCRIPTIONal FGF60_RS22505 ENOG4105C7N Xanthine uracil vitamin C permease FGF60_RS22510 ENOG4105EEQ Na H antiporter FGF60_RS22515 ENOG4105CMU LysR family (Transcriptional regulator FGF60_RS22525 ENOG41067MG lrgb family FGF60_RS22535 ENOG41062QD Membrane FGF60_RS22540 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FGF60_RS22545 ENOG4105EAU Plays a role in nitrite reduction (By similarity) FGF60_RS22550 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit FGF60_RS22555 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FGF60_RS22560 ENOG4105DVI reductase, NrfD FGF60_RS22565 ENOG4108QKW cytochrome c-type biogenesis protein FGF60_RS22570 ENOG4108W0S formate-dependent nitrite reductase complex FGF60_RS22575 ENOG4105CK2 sodium dicarboxylate symporter FGF60_RS22580 ENOG41082ND Uncharacterized protein yjcO FGF60_RS22595 ENOG410870W N-acetyltransferase FGF60_RS22600 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase FGF60_RS22605 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FGF60_RS22610 ENOG4105CSH Transporter FGF60_RS22620 ENOG4105ECM Sensor protein basS pmrB FGF60_RS22625 ENOG4105XJC Two component transcriptional regulator (Winged helix family FGF60_RS22630 ENOG4105DIJ Phosphoethanolamine transferase FGF60_RS22635 ENOG4105D5Q Arginine ornithine antiporter FGF60_RS22640 ENOG4106ZGR Transcriptional regulator FGF60_RS22645 ENOG4105CXN decarboxylase FGF60_RS22650 ENOG4108K2B transcriptional regulator FGF60_RS22655 ENOG4105F8D glycoside hydrolase family 4 FGF60_RS22660 ENOG4105CT4 transporter FGF60_RS22665 ENOG4107GFK fumarate FGF60_RS22670 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FGF60_RS22680 ENOG4108MRH transcriptional regulatory protein FGF60_RS22685 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FGF60_RS22690 ENOG4107QY8 reductase FGF60_RS22695 ENOG4105QAX Iron-sulfur FGF60_RS22700 ENOG4107KGK dmso reductase anchor subunit FGF60_RS22705 ENOG4108NEM leader-binding protein dmsD FGF60_RS22715 ENOG4108ZK4 sdia-regulated domain-containing protein FGF60_RS22720 ENOG4108RS6 transposase FGF60_RS22735 ENOG41068CG regulatoR FGF60_RS22760 ENOG4105SBG acid phosphatase FGF60_RS22785 ENOG4108SIC Transcriptional regulator FGF60_RS22790 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FGF60_RS22805 ENOG4108IJ0 Aspartate ammonia-lyase FGF60_RS22810 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 FGF60_RS22815 ENOG4105DVH amino acid FGF60_RS22830 ENOG4108ZVF (LipO)protein FGF60_RS22835 ENOG4105MTB Uncharacterized protein YjeJ FGF60_RS22840 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FGF60_RS22845 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FGF60_RS22855 ENOG4106BSU Entericidin B FGF60_RS22865 ENOG4105KPY Small multidrug resistance protein FGF60_RS22875 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) FGF60_RS22885 ENOG4105E33 succinate dehydrogenase FGF60_RS22890 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FGF60_RS22900 ENOG4107SC7 Inner membrane transporter yjeM FGF60_RS22910 ENOG4105EGS Mechanosensitive ion channel FGF60_RS22925 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) FGF60_RS22930 ENOG4106TNF Periplasmic binding protein FGF60_RS22950 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FGF60_RS22955 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FGF60_RS22960 ENOG4105K8N protein family UPF0079, ATPase FGF60_RS22965 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FGF60_RS22970 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FGF60_RS22980 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FGF60_RS22985 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FGF60_RS22990 ENOG4107QJR hflk protein FGF60_RS22995 ENOG4105EPW hflc protein FGF60_RS23015 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FGF60_RS23020 ENOG4105C2N RNA methyltransferase TrmH family group 3 FGF60_RS23025 ENOG4105FUX Conserved Protein FGF60_RS23030 ENOG4108P9J Phage shock protein A FGF60_RS23040 ENOG4107VNS Protein of unknown function (DUF2491) FGF60_RS23045 ENOG4105Z6B inner membrane protein yjfl FGF60_RS23050 ENOG4108KXT Conserved Protein FGF60_RS23055 ENOG4106032 Glutathionylspermidine synthase FGF60_RS23060 ENOG4105CSU acyl-Coa dehydrogenase FGF60_RS23065 ENOG4105S17 UPF0379 protein yjfN FGF60_RS23070 ENOG4105WSB biofilm stress and motility protein A FGF60_RS23075 ENOG4108MXZ Esterase FGF60_RS23090 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FGF60_RS23110 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase FGF60_RS23120 ENOG4105KIT UPF0379 protein yjfY FGF60_RS23135 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) FGF60_RS23140 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) FGF60_RS23145 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FGF60_RS23160 ENOG4105FHY Opacity-associated protein A FGF60_RS23165 ENOG4108V1T peptidylprolyl cis-trans isomerase FGF60_RS23175 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) FGF60_RS23180 ENOG4105DXC membrane FGF60_RS23185 ENOG4105ECR NmrA family FGF60_RS23190 ENOG4105KVH Transcriptional regulator FGF60_RS23195 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic FGF60_RS23200 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FGF60_RS23205 ENOG4108UUE Transcriptional regulator FGF60_RS23210 ENOG41061GZ Protein of unknown function (DUF1107) FGF60_RS23215 ENOG4105C37 (CBS) domain FGF60_RS23235 ENOG4108ZHD aig2 family FGF60_RS23240 ENOG4105DJB Major Facilitator Superfamily FGF60_RS23245 ENOG41069H0 dihydroorotase EC 3.5.2.3 FGF60_RS23250 ENOG4105F0N pyrophosphate phospho-hydrolase FGF60_RS23260 ENOG4105DFU Cell wall formation (By similarity) FGF60_RS23265 ENOG4105CHC glucokinase (EC 2.7.1.2) FGF60_RS23270 ENOG4107QNK )-transporter FGF60_RS23280 ENOG4107QNK )-transporter FGF60_RS23285 ENOG4105DH8 myo-inositol catabolism FGF60_RS23290 ENOG4105C26 Dehydrogenase FGF60_RS23315 ENOG4108MYR Secreted protein FGF60_RS23320 ENOG4107VG4 Xylose isomerase domain protein TIM barrel FGF60_RS23330 ENOG4105D7K pfkb domain protein FGF60_RS23335 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) FGF60_RS23340 ENOG4105CK5 oxidoreductase FGF60_RS23345 ENOG4105IE8 Alpha-ketoglutarate permease FGF60_RS23355 ENOG4105F0H myo-inositol catabolism protein FGF60_RS23365 ENOG4105CMS peptidase U62, modulator of DNA gyrase FGF60_RS23370 ENOG4108XVM Cytochrome b(562) FGF60_RS23400 ENOG41069H0 dihydroorotase EC 3.5.2.3 FGF60_RS23415 ENOG4105EMD TRANSCRIPTIONal FGF60_RS23425 ENOG4105K4U addiction module toxin, RelE StbE family FGF60_RS23430 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) FGF60_RS23435 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FGF60_RS23440 ENOG4105CG3 alpha amylase, catalytic region FGF60_RS23450 ENOG4105D4X repressor FGF60_RS23470 ENOG4105KME endoribonuclease L-psp FGF60_RS23485 ENOG41077AM PyrBI operon attenuator FGF60_RS23495 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) FGF60_RS23500 ENOG4105CSX c4-dicarboxylate anaerobic carrier FGF60_RS23505 ENOG4105DBV ornithine carbamoyltransferase FGF60_RS23510 ENOG4105C5B carbamate kinase FGF60_RS23515 ENOG4105CEU Arginine dihydrolase FGF60_RS23520 ENOG4105XEP YhcH YjgK YiaL family protein FGF60_RS23525 ENOG4105DBV ornithine carbamoyltransferase FGF60_RS23530 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) FGF60_RS23535 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase FGF60_RS23545 ENOG4108MJ3 acetyltransferase FGF60_RS23550 ENOG4108M3P Membrane FGF60_RS23555 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FGF60_RS23560 ENOG4105MYG DNA polymerase iii, chi subunit FGF60_RS23570 ENOG4108M8S permease YjgP YjgQ family protein FGF60_RS23575 ENOG4108K5H permease YjgP YjgQ family protein FGF60_RS23580 ENOG4105K2J Transcriptional regulator FGF60_RS23585 ENOG4105C6Z Gluconate FGF60_RS23590 ENOG4105CHR reductase FGF60_RS23595 ENOG4105CPQ Dehydrogenase FGF60_RS23600 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FGF60_RS23605 ENOG4105DQ4 alcohol dehydrogenase FGF60_RS23645 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) FGF60_RS23675 ENOG4105CDY transcriptional regulatory protein FGF60_RS23680 ENOG4105DTA methyltransferase FGF60_RS23690 ENOG4105KZM cytoplasmic protein FGF60_RS23715 ENOG4105C6F GntR Family Transcriptional Regulator FGF60_RS23735 ENOG4107YNJ LysR family Transcriptional regulator FGF60_RS23740 ENOG4105DYB Isoaspartyl dipeptidase FGF60_RS23745 ENOG4108P2H Inner membrane protein YjiG FGF60_RS23750 ENOG41074DU domain protein FGF60_RS23755 ENOG4105CBP Major Facilitator FGF60_RS23760 ENOG4106BRA Membrane FGF60_RS23765 ENOG41083G8 Multidrug resistance protein MdtM FGF60_RS23770 ENOG4105DNE Transposase FGF60_RS23775 ENOG4105C26 Dehydrogenase FGF60_RS23805 ENOG4105CVR type I restriction-modification system FGF60_RS23810 ENOG4107SCJ type I restriction enzyme EcoKI subunit R FGF60_RS23815 ENOG4106H3A restriction FGF60_RS23830 ENOG4105CKI cobalamin synthesis protein FGF60_RS23835 ENOG4105VCD cytoplasmic protein FGF60_RS23840 ENOG4105D22 carbon starvation protein FGF60_RS23855 ENOG4108BUD transposase FGF60_RS23875 ENOG4108IQ3 PTS system FGF60_RS23880 ENOG4105ETZ PTS System FGF60_RS23885 ENOG4105F3R pts system mannose fructose sorbose family iid FGF60_RS23890 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FGF60_RS23895 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FGF60_RS23905 ENOG4105RI1 glycoprotein receptor FGF60_RS23910 ENOG4106CVF DNA replication protein FGF60_RS23925 ENOG4105DWK Membrane FGF60_RS23930 ENOG4108N8T regulatoR FGF60_RS23935 ENOG4108T94 DNA-binding transcriptional activator BglJ FGF60_RS23940 ENOG4108UIN ybak prolyl-trna synthetase associated region FGF60_RS23945 ENOG4108819 ferric iron reductase FGF60_RS23950 ENOG4105BZU Histidine kinase FGF60_RS23955 ENOG4105YBH Protein of unknown function (DUF1435) FGF60_RS23980 ENOG4108WPU DNA polymerase III subunit psi FGF60_RS23985 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FGF60_RS23990 ENOG4105PAD Hydrolase FGF60_RS24000 ENOG4105K3G Periplasmic Protein FGF60_RS24010 ENOG4108NRW Phospholipase, patatin family FGF60_RS24015 ENOG4105EYA deoxyribonuclease FGF60_RS24020 ENOG41076CZ activating enzyme FGF60_RS24025 ENOG4105G0K glycine radical enzyme YjjI family FGF60_RS24055 ENOG4105E6S usher protein( FGF60_RS24060 ENOG4108S1B Periplasmic chaperone protein FGF60_RS24065 ENOG4105UMR response to DNA damage stimulus FGF60_RS24080 ENOG41062Z9 Membrane FGF60_RS24085 ENOG4105EAC phosphoserine phosphatase FGF60_RS24090 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FGF60_RS24095 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase FGF60_RS24100 ENOG4105C5H ABC transporter FGF60_RS24105 ENOG4107SC1 transglycosylase FGF60_RS24115 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FGF60_RS24125 ENOG4105UEI Transcriptional Regulator AraC Family FGF60_RS24130 ENOG4108RH0 Crea protein FGF60_RS24135 ENOG4105E3W Two component transcriptional regulator (Winged helix family FGF60_RS24140 ENOG4105EB3 Histidine kinase FGF60_RS24145 ENOG4105CT7 inner membrane cred family protein FGF60_RS24160 ENOG4105CW0 outer membrane usher protein FGF60_RS24165 ENOG4108VCD Chaperone FGF60_RS24175 ENOG4108PNB DNA-binding transcriptional regulator FGF60_RS24185 ENOG41065U4 response regulator FGF60_RS24190 ENOG410759A FGF60_RS24195 ENOG4106FVC RNA methyltransferase FGF60_RS24225 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity)