locus-tag	class	description
EIO66_RS00005	COG0527	aspartate kinase activity
EIO66_RS00005	COG0460	homoserine dehydrogenase
EIO66_RS00015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EIO66_RS00025	COG1115	amino acid carrier protein
EIO66_RS00035	COG0521	Mo-molybdopterin cofactor biosynthetic process
EIO66_RS00040	COG1584	GPR1 FUN34 yaaH family protein
EIO66_RS00045	COG4735	regulation of single-species biofilm formation
EIO66_RS00100	COG3039	Transposase
EIO66_RS00115	COG3188	usher protein
EIO66_RS00130	COG3539	Fimbrial protein
EIO66_RS00135	COG3121	Chaperone
EIO66_RS00155	COG0583	DNA-binding transcription factor activity
EIO66_RS00170	COG0737	Belongs to the 5'-nucleotidase family
EIO66_RS00180	COG3119	arylsulfatase activity
EIO66_RS00185	COG0641	radical SAM
EIO66_RS00205	COG0583	DNA-binding transcription factor activity
EIO66_RS00230	COG0196	riboflavin kinase activity
EIO66_RS00245	COG1047	Peptidyl-prolyl cis-trans
EIO66_RS00280	COG5016	pyruvate
EIO66_RS00280	COG0511	ligase activity, forming carbon-carbon bonds
EIO66_RS00390	COG0644	oxidoreductase
EIO66_RS00400	COG2271	Major facilitator Superfamily
EIO66_RS00420	COG3119	arylsulfatase activity
EIO66_RS00455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EIO66_RS00485	COG0417	DNA replication proofreading
EIO66_RS00525	COG0586	Pfam SNARE associated Golgi protein
EIO66_RS00615	COG0768	penicillin binding
EIO66_RS00625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EIO66_RS00640	COG0772	Belongs to the SEDS family
EIO66_RS00665	COG0849	cell division
EIO66_RS00670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EIO66_RS00690	COG0494	nUDIX hydrolase
EIO66_RS00725	COG1459	type II secretion system
EIO66_RS00730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EIO66_RS00735	COG4969	Belongs to the N-Me-Phe pilin family
EIO66_RS00755	COG3725	Membrane protein required for beta-lactamase induction
EIO66_RS00760	COG3940	Belongs to the glycosyl hydrolase 43 family
EIO66_RS00765	COG2211	Major facilitator Superfamily
EIO66_RS00780	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EIO66_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIO66_RS00790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIO66_RS00805	COG3064	Membrane
EIO66_RS00875	COG1349	DNA-binding transcription factor activity
EIO66_RS00895	COG2132	Multicopper oxidase
EIO66_RS00900	COG4993	Dehydrogenase
EIO66_RS00910	COG0288	reversible hydration of carbon dioxide
EIO66_RS00915	COG1131	(ABC) transporter
EIO66_RS00920	COG0842	Transport permease protein
EIO66_RS00925	COG3539	Fimbrial protein
EIO66_RS00945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS00950	COG0726	polysaccharide deacetylase
EIO66_RS01000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EIO66_RS01025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EIO66_RS01030	COG1643	Atp-dependent helicase
EIO66_RS01035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIO66_RS01040	COG4774	siderophore transport
EIO66_RS01045	COG1120	ATPase activity
EIO66_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EIO66_RS01070	COG3188	usher protein
EIO66_RS01075	COG3121	Chaperone
EIO66_RS01080	COG3539	Fimbrial protein
EIO66_RS01085	COG3539	Fimbrial protein
EIO66_RS01115	COG2860	membrane
EIO66_RS01140	COG3835	regulator
EIO66_RS01150	COG0477	Major facilitator Superfamily
EIO66_RS01200	COG0575	Belongs to the CDS family
EIO66_RS01265	COG0346	lactoylglutathione lyase activity
EIO66_RS01275	COG4568	rho-dependent transcription termination
EIO66_RS01290	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EIO66_RS01295	COG3015	lipoprotein NlpE involved in copper resistance
EIO66_RS01305	COG1720	tRNA m6t6A37 methyltransferase activity
EIO66_RS01330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EIO66_RS01370	COG0656	L-ascorbic acid biosynthetic process
EIO66_RS01375	COG0583	DNA-binding transcription factor activity
EIO66_RS01380	COG2814	Major facilitator Superfamily
EIO66_RS01390	COG2226	methyltransferase
EIO66_RS01395	COG0741	lytic transglycosylase activity
EIO66_RS01395	COG1388	LysM domain
EIO66_RS01405	COG2226	methyltransferase
EIO66_RS01515	COG3047	cAMP biosynthetic process
EIO66_RS01515	COG2885	chlorophyll binding
EIO66_RS01555	COG3039	Transposase
EIO66_RS01580	COG3501	Rhs element vgr protein
EIO66_RS01590	COG3209	COG3209 Rhs family protein
EIO66_RS01615	COG3501	Rhs element vgr protein
EIO66_RS01640	COG3209	COG3209 Rhs family protein
EIO66_RS01730	COG1522	sequence-specific DNA binding
EIO66_RS01775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EIO66_RS01790	COG0121	glutamine amidotransferase
EIO66_RS01795	COG3034	peptidoglycan biosynthetic process
EIO66_RS01805	COG1690	Belongs to the RtcB family
EIO66_RS01810	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EIO66_RS01815	COG2195	Cleaves the N-terminal amino acid of tripeptides
EIO66_RS01855	COG0582	viral genome integration into host DNA
EIO66_RS01950	COG3179	chitinase
EIO66_RS01975	COG1802	Transcriptional regulator
EIO66_RS01975	COG4626	Terminase
EIO66_RS01980	COG4695	Portal protein
EIO66_RS01985	COG0740	serine-type endopeptidase activity
EIO66_RS02110	COG3188	usher protein
EIO66_RS02120	COG3039	Transposase
EIO66_RS02130	COG3539	Fimbrial protein
EIO66_RS02145	COG2200	EAL domain
EIO66_RS02195	COG2217	Heavy metal translocating P-type atpase
EIO66_RS02200	COG0789	Transcriptional regulator
EIO66_RS02210	COG2814	Major facilitator Superfamily
EIO66_RS02230	COG1271	oxidase subunit
EIO66_RS02235	COG1294	oxidase, subunit
EIO66_RS02255	COG1280	lysine exporter protein (LysE YggA)
EIO66_RS02290	COG0113	porphobilinogen synthase activity
EIO66_RS02295	COG3039	Transposase
EIO66_RS02310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIO66_RS02320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EIO66_RS02365	COG3706	GGDEF domain
EIO66_RS02370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EIO66_RS02390	COG4126	flavin adenine dinucleotide binding
EIO66_RS02405	COG1940	carbohydrate kinase activity
EIO66_RS02410	COG2814	Major facilitator Superfamily
EIO66_RS02415	COG0419	ATPase involved in DNA repair
EIO66_RS02420	COG0420	3'-5' exonuclease activity
EIO66_RS02430	COG5002	protein histidine kinase activity
EIO66_RS02445	COG0366	Alpha amylase catalytic
EIO66_RS02450	COG0450	alkyl hydroperoxide reductase
EIO66_RS02470	COG1862	Preprotein translocase
EIO66_RS02480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIO66_RS02515	COG4238	major outer membrane lipoprotein
EIO66_RS02525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIO66_RS02525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIO66_RS02545	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EIO66_RS02550	COG0667	Aldo Keto reductase
EIO66_RS02560	COG0142	geranyltranstransferase activity
EIO66_RS02595	COG2188	Transcriptional regulator
EIO66_RS02625	COG2814	Major facilitator Superfamily
EIO66_RS02650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EIO66_RS02655	COG1845	cytochrome c oxidase, subunit III
EIO66_RS02660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EIO66_RS02665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EIO66_RS02670	COG2223	nitrite transmembrane transporter activity
EIO66_RS02675	COG3056	Lipoprotein
EIO66_RS02680	COG0271	Belongs to the BolA IbaG family
EIO66_RS02705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EIO66_RS02715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EIO66_RS02720	COG1555	photosystem II stabilization
EIO66_RS02725	COG0824	Thioesterase
EIO66_RS02735	COG4533	DNA binding
EIO66_RS02750	COG1522	sequence-specific DNA binding
EIO66_RS02755	COG1132	(ABC) transporter
EIO66_RS02760	COG1132	(ABC) transporter
EIO66_RS02765	COG0347	Belongs to the P(II) protein family
EIO66_RS02770	COG0004	ammonium transporteR
EIO66_RS02775	COG1946	Acyl-CoA thioesterase
EIO66_RS02780	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EIO66_RS02785	COG3695	enzyme binding
EIO66_RS02795	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EIO66_RS02815	COG0110	maltose O-acetyltransferase activity
EIO66_RS02830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EIO66_RS02835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIO66_RS02840	COG1309	transcriptional regulator
EIO66_RS02850	COG5464	transposase or invertase
EIO66_RS02860	COG3923	Primosomal replication protein n
EIO66_RS02865	COG2832	Protein of unknown function (DUF454)
EIO66_RS02910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIO66_RS02915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EIO66_RS02915	COG4651	solute:proton antiporter activity
EIO66_RS02920	COG2223	nitrite transmembrane transporter activity
EIO66_RS02935	COG3735	TraB family
EIO66_RS02945	COG2217	Heavy metal translocating P-type atpase
EIO66_RS02955	COG1585	Membrane protein implicated in regulation of membrane protease activity
EIO66_RS02960	COG0330	HflC and HflK could
EIO66_RS02965	COG4619	ABC transporter
EIO66_RS02970	COG0390	transport system, permease component
EIO66_RS02975	COG3118	belongs to the thioredoxin family
EIO66_RS02980	COG0300	oxidoreductase activity
EIO66_RS02985	COG2755	lipolytic protein G-D-S-L family
EIO66_RS02990	COG4181	ATPase activity
EIO66_RS02995	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EIO66_RS03005	COG1464	Belongs to the NlpA lipoprotein family
EIO66_RS03040	COG3960	tartronate-semialdehyde synthase activity
EIO66_RS03045	COG3622	Belongs to the hyi family
EIO66_RS03050	COG2084	Dehydrogenase
EIO66_RS03075	COG3257	ureidoglycine aminohydrolase activity
EIO66_RS03080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EIO66_RS03085	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EIO66_RS03090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EIO66_RS03095	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EIO66_RS03105	COG0549	Belongs to the carbamate kinase family
EIO66_RS03110	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EIO66_RS03115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EIO66_RS03125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EIO66_RS03145	COG1988	membrane-bound metal-dependent
EIO66_RS03150	COG2501	S4 domain
EIO66_RS03240	COG0463	Glycosyl transferase, family 2
EIO66_RS03245	COG2246	polysaccharide biosynthetic process
EIO66_RS03265	COG2207	Transcriptional regulator
EIO66_RS03270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIO66_RS03280	COG3059	membrane
EIO66_RS03290	COG1113	amino acid transport
EIO66_RS03295	COG0668	transmembrane transport
EIO66_RS03305	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EIO66_RS03305	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EIO66_RS03310	COG2222	sugar isomerase
EIO66_RS03320	COG3716	PTS system mannose fructose sorbose family IID component
EIO66_RS03345	COG2315	Protein conserved in bacteria
EIO66_RS03375	COG4771	TonB-dependent receptor
EIO66_RS03380	COG2382	esterase
EIO66_RS03385	COG3251	PFAM MbtH domain protein
EIO66_RS03390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EIO66_RS03390	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EIO66_RS03395	COG3039	Transposase
EIO66_RS03400	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EIO66_RS03405	COG1120	ATPase activity
EIO66_RS03410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EIO66_RS03415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EIO66_RS03425	COG4592	Periplasmic binding protein
EIO66_RS03430	COG1169	isochorismate synthase
EIO66_RS03435	COG1021	2,3-dihydroxybenzoate-AMP ligase
EIO66_RS03440	COG1535	isochorismatase
EIO66_RS03440	COG3433	isochorismatase activity
EIO66_RS03445	COG1028	Short-chain dehydrogenase reductase Sdr
EIO66_RS03455	COG1966	Carbon starvation protein
EIO66_RS03460	COG2879	small protein
EIO66_RS03465	COG0371	Dehydrogenase
EIO66_RS03470	COG0436	Aminotransferase
EIO66_RS03475	COG1475	DNA binding
EIO66_RS03480	COG3969	phosphoadenosine phosphosulfate
EIO66_RS03485	COG0583	DNA-binding transcription factor activity
EIO66_RS03490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EIO66_RS03510	COG0243	molybdopterin cofactor binding
EIO66_RS03530	COG1063	alcohol dehydrogenase
EIO66_RS03535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EIO66_RS03540	COG3719	Belongs to the RNase T2 family
EIO66_RS03545	COG0471	metal ion transport
EIO66_RS03560	COG3051	citrate lyase alpha subunit
EIO66_RS03565	COG2301	Belongs to the HpcH HpaI aldolase family
EIO66_RS03575	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EIO66_RS03580	COG3290	protein histidine kinase activity
EIO66_RS03585	COG4565	transcriptional regulatory protein
EIO66_RS03590	COG3069	C4-dicarboxylate transmembrane transporter activity
EIO66_RS03610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EIO66_RS03625	COG0583	DNA-binding transcription factor activity
EIO66_RS03640	COG1686	Belongs to the peptidase S11 family
EIO66_RS03650	COG0772	Belongs to the SEDS family
EIO66_RS03655	COG0768	penicillin binding
EIO66_RS03665	COG0799	negative regulation of ribosome biogenesis
EIO66_RS03675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EIO66_RS03685	COG1466	dna polymerase III delta subunit
EIO66_RS03715	COG3829	transcription factor binding
EIO66_RS03715	COG3290	protein histidine kinase activity
EIO66_RS03720	COG2888	peptidyl-tyrosine sulfation
EIO66_RS03735	COG2214	Heat shock protein DnaJ domain protein
EIO66_RS03745	COG2214	Heat shock protein DnaJ domain protein
EIO66_RS03750	COG0443	Heat shock 70 kDa protein
EIO66_RS03765	COG1126	abc transporter atp-binding protein
EIO66_RS03770	COG0765	amino acid transport
EIO66_RS03775	COG0765	amino acid transport
EIO66_RS03800	COG1702	phosphate starvation-inducible protein PhoH
EIO66_RS03810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIO66_RS03855	COG0367	asparagine synthase
EIO66_RS03860	COG0647	UMP catabolic process
EIO66_RS03865	COG1940	carbohydrate kinase activity
EIO66_RS03865	COG1846	Transcriptional regulator
EIO66_RS03870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EIO66_RS03915	COG1053	succinate dehydrogenase
EIO66_RS03920	COG0583	DNA-binding transcription factor activity
EIO66_RS03925	COG0735	belongs to the Fur family
EIO66_RS03940	COG0596	Alpha beta hydrolase
EIO66_RS03950	COG0033	Phosphoglucomutase
EIO66_RS03960	COG0531	amino acid
EIO66_RS03965	COG1982	Orn Lys Arg decarboxylase major
EIO66_RS03975	COG0745	RESPONSE REGULATOR receiver
EIO66_RS03980	COG2205	protein histidine kinase activity
EIO66_RS04025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EIO66_RS04030	COG1984	allophanate hydrolase subunit 2
EIO66_RS04045	COG0582	viral genome integration into host DNA
EIO66_RS04085	COG1216	Glycosyl transferase, family 2
EIO66_RS04110	COG3180	Ammonia monooxygenase
EIO66_RS04125	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EIO66_RS04140	COG0567	Dehydrogenase, E1 component
EIO66_RS04145	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIO66_RS04155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EIO66_RS04160	COG1271	oxidase subunit
EIO66_RS04165	COG1294	oxidase, subunit
EIO66_RS04170	COG4890	Cyd operon protein YbgT
EIO66_RS04175	COG3790	cyd operon protein YbgE
EIO66_RS04180	COG0824	Thioesterase
EIO66_RS04185	COG0811	peptide transport
EIO66_RS04190	COG0848	biopolymer transport protein
EIO66_RS04195	COG3064	Membrane
EIO66_RS04205	COG2885	chlorophyll binding
EIO66_RS04210	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EIO66_RS04265	COG1230	cation diffusion facilitator family transporter
EIO66_RS04275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EIO66_RS04280	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EIO66_RS04280	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EIO66_RS04290	COG0583	DNA-binding transcription factor activity
EIO66_RS04295	COG0583	DNA-binding transcription factor activity
EIO66_RS04300	COG0471	metal ion transport
EIO66_RS04300	COG0490	domain, Protein
EIO66_RS04335	COG2017	converts alpha-aldose to the beta-anomer
EIO66_RS04360	COG1119	ATPase activity
EIO66_RS04365	COG3585	molybdate ion transport
EIO66_RS04365	COG2005	Transcriptional regulator
EIO66_RS04375	COG0725	ABC transporter, periplasmic molybdate-binding protein
EIO66_RS04380	COG4149	molybdate abc transporter
EIO66_RS04390	COG0561	phosphatase activity
EIO66_RS04400	COG4677	pectinesterase activity
EIO66_RS04430	COG1881	PFAM PEBP family protein
EIO66_RS04480	COG3039	Transposase
EIO66_RS04505	COG0521	Mo-molybdopterin cofactor biosynthetic process
EIO66_RS04515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EIO66_RS04525	COG0670	Belongs to the BI1 family
EIO66_RS04545	COG0392	lysyltransferase activity
EIO66_RS04550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EIO66_RS04555	COG3568	Endonuclease Exonuclease Phosphatase
EIO66_RS04565	COG0842	Transport permease protein
EIO66_RS04570	COG0842	Transport permease protein
EIO66_RS04575	COG1131	(ABC) transporter
EIO66_RS04585	COG1309	transcriptional regulator
EIO66_RS04590	COG0513	Belongs to the DEAD box helicase family
EIO66_RS04600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EIO66_RS04610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EIO66_RS04620	COG0668	transmembrane transport
EIO66_RS04625	COG1126	abc transporter atp-binding protein
EIO66_RS04630	COG0765	amino acid transport
EIO66_RS04635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIO66_RS04650	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EIO66_RS04655	COG2194	sulfuric ester hydrolase activity
EIO66_RS04670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EIO66_RS04675	COG1376	ErfK ybiS ycfS ynhG family protein
EIO66_RS04680	COG0488	(ABC) transporter
EIO66_RS04685	COG3039	Transposase
EIO66_RS04705	COG0561	phosphatase activity
EIO66_RS04710	COG1882	Formate acetyltransferase
EIO66_RS04715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EIO66_RS04740	COG0747	negative chemotaxis
EIO66_RS04765	COG2133	pyrroloquinoline quinone binding
EIO66_RS04770	COG0625	glutathione transferase activity
EIO66_RS04775	COG1686	Belongs to the peptidase S11 family
EIO66_RS04780	COG1349	DNA-binding transcription factor activity
EIO66_RS04785	COG0671	phosphoesterase, PA-phosphatase related
EIO66_RS04790	COG2814	Major facilitator Superfamily
EIO66_RS04795	COG0561	phosphatase activity
EIO66_RS04800	COG0738	Major facilitator superfamily
EIO66_RS04805	COG3226	Transcriptional regulator
EIO66_RS04850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EIO66_RS04855	COG3842	ATPase activity
EIO66_RS04860	COG1176	ABC-type spermidine putrescine transport system, permease component I
EIO66_RS04865	COG1177	transmembrane transport
EIO66_RS04895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIO66_RS04900	COG4160	amino acid transport
EIO66_RS04905	COG4215	(ABC) transporter
EIO66_RS04910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIO66_RS04915	COG1126	abc transporter atp-binding protein
EIO66_RS04930	COG3023	N-Acetylmuramoyl-L-alanine amidase
EIO66_RS04935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIO66_RS04940	COG0702	epimerase
EIO66_RS04945	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EIO66_RS04950	COG0028	Belongs to the TPP enzyme family
EIO66_RS04955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIO66_RS04965	COG2431	L-lysine efflux transmembrane transporter activity
EIO66_RS04970	COG3593	DNA synthesis involved in DNA repair
EIO66_RS04975	COG2990	Protein conserved in bacteria
EIO66_RS04980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIO66_RS04985	COG1136	(ABC) transporter
EIO66_RS04985	COG0577	efflux transmembrane transporter activity
EIO66_RS04990	COG1278	Cold shock
EIO66_RS05000	COG0542	response to heat
EIO66_RS05025	COG1335	isochorismatase
EIO66_RS05035	COG0583	DNA-binding transcription factor activity
EIO66_RS05055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EIO66_RS05060	COG4988	ABC transporter
EIO66_RS05065	COG0492	ferredoxin-NADP+ reductase activity
EIO66_RS05070	COG3039	Transposase
EIO66_RS05090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EIO66_RS05100	COG0243	molybdopterin cofactor binding
EIO66_RS05105	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS05110	COG3302	dmso reductase anchor subunit
EIO66_RS05120	COG0531	amino acid
EIO66_RS05125	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EIO66_RS05140	COG1882	Formate acetyltransferase
EIO66_RS05145	COG2116	formate transmembrane transporter activity
EIO66_RS05150	COG1944	ATP diphosphatase activity
EIO66_RS05155	COG2323	membrane
EIO66_RS05170	COG0501	Belongs to the peptidase M48B family
EIO66_RS05180	COG0539	negative regulation of cytoplasmic translation
EIO66_RS05190	COG2333	competence protein COMEC
EIO66_RS05190	COG0658	competence protein
EIO66_RS05205	COG3214	Protein conserved in bacteria
EIO66_RS05225	COG3173	Aminoglycoside phosphotransferase
EIO66_RS05230	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EIO66_RS05235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EIO66_RS05245	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EIO66_RS05255	COG2989	Protein conserved in bacteria
EIO66_RS05260	COG3108	Peptidase M15
EIO66_RS05265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIO66_RS05275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EIO66_RS05285	COG1522	sequence-specific DNA binding
EIO66_RS05300	COG1115	amino acid carrier protein
EIO66_RS05310	COG0308	aminopeptidase N
EIO66_RS05325	COG3217	Mosc domain protein beta barrel domain protein
EIO66_RS05325	COG0633	Ferredoxin
EIO66_RS05335	COG0488	(ABC) transporter
EIO66_RS05340	COG2995	paraquat-inducible protein a
EIO66_RS05345	COG3008	intermembrane lipid transfer
EIO66_RS05345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EIO66_RS05350	COG3009	Protein conserved in bacteria
EIO66_RS05355	COG3130	regulation of translation
EIO66_RS05365	COG1067	ATP-dependent peptidase activity
EIO66_RS05385	COG3070	regulator of competence-specific genes
EIO66_RS05390	COG1289	transmembrane transporter activity
EIO66_RS05395	COG3304	Inner membrane component domain
EIO66_RS05400	COG0210	DNA helicase
EIO66_RS05415	COG1832	CoA-binding protein
EIO66_RS05430	COG1881	PFAM PEBP family protein
EIO66_RS05450	COG0670	Belongs to the BI1 family
EIO66_RS05505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EIO66_RS05520	COG1396	sequence-specific DNA binding
EIO66_RS05545	COG0305	Participates in initiation and elongation during chromosome replication
EIO66_RS05605	COG3772	lysozyme
EIO66_RS05645	COG0494	nUDIX hydrolase
EIO66_RS05735	COG5301	cellulose 1,4-beta-cellobiosidase activity
EIO66_RS05815	COG2205	protein histidine kinase activity
EIO66_RS05820	COG0745	RESPONSE REGULATOR receiver
EIO66_RS05835	COG2368	4-hydroxyphenylacetate
EIO66_RS05840	COG1846	Transcriptional regulator
EIO66_RS05850	COG1012	belongs to the aldehyde dehydrogenase family
EIO66_RS05855	COG3384	dioxygenase
EIO66_RS05865	COG3971	2-oxopent-4-enoate hydratase activity
EIO66_RS05915	COG4232	protein-disulfide reductase activity
EIO66_RS05920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EIO66_RS05920	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EIO66_RS05925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIO66_RS05945	COG3729	General stress protein
EIO66_RS05950	COG1309	transcriptional regulator
EIO66_RS05970	COG1702	phosphate starvation-inducible protein PhoH
EIO66_RS06010	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EIO66_RS06020	COG1418	mRNA catabolic process
EIO66_RS06025	COG0270	DNA (cytosine-5-)-methyltransferase activity
EIO66_RS06030	COG3727	T/G mismatch-specific endonuclease activity
EIO66_RS06035	COG0697	spore germination
EIO66_RS06040	COG2354	Protein conserved in bacteria
EIO66_RS06045	COG5475	Uncharacterized small protein (DUF2158)
EIO66_RS06150	COG0425	Belongs to the sulfur carrier protein TusA family
EIO66_RS06195	COG3039	Transposase
EIO66_RS06235	COG2197	response regulator
EIO66_RS06250	COG2197	response regulator
EIO66_RS06295	COG3318	Belongs to the UPF0149 family
EIO66_RS06295	COG3012	SEC-C Motif Domain Protein
EIO66_RS06300	COG0814	amino acid
EIO66_RS06310	COG1528	Iron-storage protein
EIO66_RS06325	COG1528	Iron-storage protein
EIO66_RS06430	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EIO66_RS06445	COG3102	Protein conserved in bacteria
EIO66_RS06465	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EIO66_RS06470	COG1801	Protein of unknown function DUF72
EIO66_RS06475	COG5301	cellulose 1,4-beta-cellobiosidase activity
EIO66_RS06515	COG2135	peptidase activity
EIO66_RS06525	COG1335	isochorismatase
EIO66_RS06535	COG0494	nUDIX hydrolase
EIO66_RS06575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EIO66_RS06585	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EIO66_RS06590	COG0739	heme binding
EIO66_RS06595	COG1560	Kdo2-lipid A biosynthetic process
EIO66_RS06605	COG1737	Transcriptional regulator
EIO66_RS06615	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EIO66_RS06620	COG0129	dihydroxy-acid dehydratase activity
EIO66_RS06625	COG0800	Aldolase
EIO66_RS06635	COG3141	response to X-ray
EIO66_RS06645	COG2979	Protein of unknown function (DUF533)
EIO66_RS06650	COG1770	oligopeptidase
EIO66_RS06655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EIO66_RS06660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EIO66_RS06670	COG2372	response to copper ion
EIO66_RS06675	COG1276	copper resistance
EIO66_RS06740	COG5562	phage envelope protein
EIO66_RS06780	COG3008	intermembrane lipid transfer
EIO66_RS06785	COG2995	paraquat-inducible protein a
EIO66_RS06790	COG1956	GAF domain-containing protein
EIO66_RS06810	COG2814	Major facilitator Superfamily
EIO66_RS06815	COG1414	Transcriptional regulator
EIO66_RS06845	COG0768	penicillin binding
EIO66_RS06850	COG2226	methyltransferase
EIO66_RS06865	COG3716	PTS system mannose fructose sorbose family IID component
EIO66_RS06870	COG3715	PTS system
EIO66_RS06875	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIO66_RS06875	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS06880	COG1253	flavin adenine dinucleotide binding
EIO66_RS06885	COG2200	EAL domain
EIO66_RS06890	COG1760	l-serine dehydratase
EIO66_RS06910	COG0251	oxidation-reduction process
EIO66_RS06915	COG1199	ATP-dependent helicase activity
EIO66_RS06925	COG3065	identical protein binding
EIO66_RS06935	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EIO66_RS06945	COG2894	cell division
EIO66_RS06960	COG0179	Fumarylacetoacetate (FAA) hydrolase
EIO66_RS07000	COG2719	SpoVR family
EIO66_RS07020	COG1619	proteins homologs of microcin C7 resistance protein MccF
EIO66_RS07045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EIO66_RS07055	COG1294	oxidase, subunit
EIO66_RS07060	COG1271	oxidase subunit
EIO66_RS07065	COG1773	rubredoxin
EIO66_RS07070	COG1999	signal sequence binding
EIO66_RS07075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EIO66_RS07080	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
EIO66_RS07090	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EIO66_RS07110	COG0012	GTP binding
EIO66_RS07125	COG0659	secondary active sulfate transmembrane transporter activity
EIO66_RS07175	COG0387	Pfam Sodium calcium exchanger
EIO66_RS07180	COG4572	Cation transport regulator
EIO66_RS07185	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EIO66_RS07190	COG4932	domain protein
EIO66_RS07195	COG2197	response regulator
EIO66_RS07200	COG3850	Histidine kinase
EIO66_RS07210	COG2223	nitrite transmembrane transporter activity
EIO66_RS07215	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EIO66_RS07220	COG1140	nitrate reductase beta subunit
EIO66_RS07225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EIO66_RS07230	COG2181	nitrate reductase activity
EIO66_RS07270	COG0788	formyltetrahydrofolate deformylase activity
EIO66_RS07280	COG1752	Esterase of the alpha-beta hydrolase superfamily
EIO66_RS07285	COG0745	RESPONSE REGULATOR receiver
EIO66_RS07290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EIO66_RS07305	COG1012	belongs to the aldehyde dehydrogenase family
EIO66_RS07305	COG1454	alcohol dehydrogenase
EIO66_RS07310	COG2095	MarC family integral membrane protein
EIO66_RS07345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIO66_RS07365	COG2350	Protein conserved in bacteria
EIO66_RS07390	COG0727	PFAM Uncharacterised protein family (UPF0153)
EIO66_RS07395	COG3047	cAMP biosynthetic process
EIO66_RS07400	COG3546	catalase activity
EIO66_RS07405	COG3685	Protein conserved in bacteria
EIO66_RS07410	COG3685	Protein conserved in bacteria
EIO66_RS07415	COG3729	General stress protein
EIO66_RS07455	COG0009	L-threonylcarbamoyladenylate synthase
EIO66_RS07470	COG1028	Short-chain dehydrogenase reductase Sdr
EIO66_RS07475	COG0616	signal peptide processing
EIO66_RS07520	COG0671	phosphoesterase, PA-phosphatase related
EIO66_RS07525	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EIO66_RS07530	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EIO66_RS07550	COG1349	DNA-binding transcription factor activity
EIO66_RS07560	COG5001	Diguanylate cyclase
EIO66_RS07570	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EIO66_RS07570	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EIO66_RS07625	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EIO66_RS07630	COG1842	Phage shock protein A
EIO66_RS07640	COG1983	PspC domain protein
EIO66_RS07650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIO66_RS07655	COG3106	COG3106 Predicted ATPase
EIO66_RS07675	COG4948	Mandelate Racemase Muconate Lactonizing
EIO66_RS07680	COG2866	Carboxypeptidase
EIO66_RS07685	COG4166	transmembrane transport
EIO66_RS07690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EIO66_RS07705	COG3302	dmso reductase anchor subunit
EIO66_RS07710	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS07715	COG0243	molybdopterin cofactor binding
EIO66_RS07735	COG4948	Mandelate Racemase Muconate Lactonizing
EIO66_RS07740	COG3039	Transposase
EIO66_RS07745	COG0814	amino acid
EIO66_RS07750	COG1028	Short-chain dehydrogenase reductase Sdr
EIO66_RS07755	COG2814	Major facilitator Superfamily
EIO66_RS07765	COG0583	DNA-binding transcription factor activity
EIO66_RS07770	COG0656	L-ascorbic acid biosynthetic process
EIO66_RS07775	COG1028	Short-chain dehydrogenase reductase Sdr
EIO66_RS07780	COG1309	transcriptional regulator
EIO66_RS07820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EIO66_RS07840	COG0668	transmembrane transport
EIO66_RS07845	COG3182	Iron-regulated membrane protein
EIO66_RS07865	COG2840	Smr protein MutS2
EIO66_RS07875	COG0840	transmembrane signaling receptor activity
EIO66_RS07890	COG0513	Belongs to the DEAD box helicase family
EIO66_RS07915	COG2076	Multidrug Resistance protein
EIO66_RS07925	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIO66_RS07925	COG0674	pyruvate-flavodoxin oxidoreductase activity
EIO66_RS07925	COG1013	pyruvate-flavodoxin oxidoreductase activity
EIO66_RS07925	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EIO66_RS07935	COG3042	response to heat
EIO66_RS07940	COG3187	Heat shock protein
EIO66_RS07945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIO66_RS07950	COG2911	Protein conserved in bacteria
EIO66_RS07960	COG3784	Protein of unknown function (DUF1318)
EIO66_RS07975	COG1643	Atp-dependent helicase
EIO66_RS07980	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EIO66_RS07985	COG3038	cytochrome b561
EIO66_RS07990	COG0500	methyltransferase
EIO66_RS08000	COG0765	amino acid transport
EIO66_RS08010	COG0765	amino acid transport
EIO66_RS08015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIO66_RS08030	COG3039	Transposase
EIO66_RS08050	COG0840	transmembrane signaling receptor activity
EIO66_RS08055	COG0583	DNA-binding transcription factor activity
EIO66_RS08060	COG5383	Protein conserved in bacteria
EIO66_RS08065	COG2272	Belongs to the type-B carboxylesterase lipase family
EIO66_RS08075	COG2353	YceI-like domain
EIO66_RS08080	COG1304	FMN binding
EIO66_RS08090	COG1349	DNA-binding transcription factor activity
EIO66_RS08095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EIO66_RS08100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS08105	COG0434	BtpA family
EIO66_RS08110	COG3775	system Galactitol-specific IIC component
EIO66_RS08115	COG3414	Phosphotransferase system galactitol-specific IIB component
EIO66_RS08125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EIO66_RS08130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EIO66_RS08135	COG1275	C4-dicarboxylate transporter malic acid transport protein
EIO66_RS08140	COG0500	methyltransferase
EIO66_RS08150	COG3135	benzoate transporter
EIO66_RS08155	COG1396	sequence-specific DNA binding
EIO66_RS08160	COG0826	peptidase U32
EIO66_RS08185	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EIO66_RS08190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EIO66_RS08230	COG3238	Protein conserved in bacteria
EIO66_RS08240	COG2130	NADP-dependent
EIO66_RS08250	COG4772	TonB-dependent receptor
EIO66_RS08255	COG3391	amine dehydrogenase activity
EIO66_RS08290	COG2181	nitrate reductase activity
EIO66_RS08295	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EIO66_RS08300	COG1140	nitrate reductase beta subunit
EIO66_RS08305	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EIO66_RS08355	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS08360	COG2864	formate dehydrogenase
EIO66_RS08365	COG1064	alcohol dehydrogenase
EIO66_RS08385	COG1764	response to oxidative stress
EIO66_RS08410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EIO66_RS08425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EIO66_RS08430	COG1757	Na H antiporter
EIO66_RS08435	COG1609	Transcriptional regulator
EIO66_RS08485	COG0251	oxidation-reduction process
EIO66_RS08490	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EIO66_RS08515	COG2271	Major facilitator Superfamily
EIO66_RS08520	COG1063	alcohol dehydrogenase
EIO66_RS08525	COG2186	Transcriptional regulator
EIO66_RS08535	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EIO66_RS08540	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EIO66_RS08565	COG1773	rubredoxin
EIO66_RS08590	COG3039	Transposase
EIO66_RS08600	COG3781	membrane
EIO66_RS08615	COG1012	belongs to the aldehyde dehydrogenase family
EIO66_RS08620	COG0583	DNA-binding transcription factor activity
EIO66_RS08660	COG2814	Major facilitator Superfamily
EIO66_RS08670	COG3111	PFAM Bacterial OB fold (BOF) protein
EIO66_RS08675	COG1546	Belongs to the CinA family
EIO66_RS08680	COG3729	General stress protein
EIO66_RS08695	COG4221	oxidoreductase activity
EIO66_RS08700	COG1802	Transcriptional regulator
EIO66_RS08710	COG0246	Mannitol dehydrogenase
EIO66_RS08715	COG0477	Major facilitator Superfamily
EIO66_RS08720	COG1063	alcohol dehydrogenase
EIO66_RS08740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EIO66_RS08755	COG0243	molybdopterin cofactor binding
EIO66_RS08760	COG0243	molybdopterin cofactor binding
EIO66_RS08765	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS08770	COG3302	dmso reductase anchor subunit
EIO66_RS08810	COG1940	carbohydrate kinase activity
EIO66_RS08815	COG0583	DNA-binding transcription factor activity
EIO66_RS08820	COG2814	Major facilitator Superfamily
EIO66_RS08830	COG3591	Belongs to the peptidase S1B family
EIO66_RS08850	COG0628	permease
EIO66_RS08855	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EIO66_RS08860	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EIO66_RS08870	COG0531	amino acid
EIO66_RS08875	COG3136	membrane protein required for alginate biosynthesis
EIO66_RS08880	COG0745	RESPONSE REGULATOR receiver
EIO66_RS08890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EIO66_RS08895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EIO66_RS08900	COG2205	protein histidine kinase activity
EIO66_RS08925	COG5339	Protein conserved in bacteria
EIO66_RS08945	COG0673	inositol 2-dehydrogenase activity
EIO66_RS08995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EIO66_RS09005	COG0625	glutathione transferase activity
EIO66_RS09025	COG3895	Periplasmic Protein
EIO66_RS09050	COG1566	PFAM secretion protein HlyD family protein
EIO66_RS09065	COG4989	oxidoreductase activity
EIO66_RS09070	COG3313	Fe-S protein
EIO66_RS09075	COG1309	transcriptional regulator
EIO66_RS09080	COG1902	pentaerythritol trinitrate reductase activity
EIO66_RS09100	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EIO66_RS09105	COG0791	NLP P60 protein
EIO66_RS09125	COG0583	DNA-binding transcription factor activity
EIO66_RS09130	COG2814	Major facilitator Superfamily
EIO66_RS09135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EIO66_RS09140	COG0307	riboflavin synthase, alpha
EIO66_RS09285	COG3039	Transposase
EIO66_RS09300	COG0789	Transcriptional regulator
EIO66_RS09305	COG3272	Protein of unknown function (DUF1722)
EIO66_RS09340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIO66_RS09350	COG2267	carboxylic ester hydrolase activity
EIO66_RS09355	COG0531	amino acid
EIO66_RS09370	COG4238	major outer membrane lipoprotein
EIO66_RS09375	COG1376	ErfK ybiS ycfS ynhG family protein
EIO66_RS09390	COG0719	Fe-S assembly protein
EIO66_RS09395	COG0396	ATPase activity
EIO66_RS09400	COG0719	Fe-S assembly protein
EIO66_RS09405	COG0316	Belongs to the HesB IscA family
EIO66_RS09420	COG2050	protein possibly involved in aromatic compounds catabolism
EIO66_RS09425	COG0277	FAD linked oxidase domain protein
EIO66_RS09425	COG0247	lactate metabolic process
EIO66_RS09430	COG0628	permease
EIO66_RS09445	COG0738	Major facilitator superfamily
EIO66_RS09450	COG2271	Major facilitator Superfamily
EIO66_RS09465	COG4670	ketone body catabolic process
EIO66_RS09470	COG1960	acyl-CoA dehydrogenase activity
EIO66_RS09475	COG1917	Cupin 2, conserved barrel domain protein
EIO66_RS09475	COG2207	Transcriptional regulator
EIO66_RS09480	COG2086	electron transfer activity
EIO66_RS09485	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EIO66_RS09490	COG0644	oxidoreductase
EIO66_RS09495	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EIO66_RS09500	COG0318	PFAM AMP-dependent synthetase and ligase
EIO66_RS09505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EIO66_RS09505	COG0574	Belongs to the PEP-utilizing enzyme family
EIO66_RS09520	COG4256	Hemin uptake protein
EIO66_RS09535	COG0791	NLP P60 protein
EIO66_RS09545	COG0386	Belongs to the glutathione peroxidase family
EIO66_RS09610	COG3137	Salt-induced outer membrane protein
EIO66_RS09615	COG1105	Belongs to the carbohydrate kinase PfkB family
EIO66_RS09625	COG3001	Fructosamine kinase
EIO66_RS09635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIO66_RS09640	COG1988	membrane-bound metal-dependent
EIO66_RS09655	COG0753	catalase activity
EIO66_RS09665	COG1486	melibiose metabolic process
EIO66_RS09670	COG1917	Cupin 2, conserved barrel domain protein
EIO66_RS09670	COG2169	Transcriptional regulator
EIO66_RS09675	COG1447	Phosphotransferase system cellobiose-specific component IIA
EIO66_RS09680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EIO66_RS09685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EIO66_RS09695	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EIO66_RS09705	COG0322	excinuclease ABC activity
EIO66_RS09710	COG3678	ATP-independent chaperone mediated protein folding
EIO66_RS09745	COG0494	nUDIX hydrolase
EIO66_RS09770	COG0778	Nitroreductase
EIO66_RS09775	COG0616	signal peptide processing
EIO66_RS09780	COG0252	asparaginase activity
EIO66_RS09785	COG1335	isochorismatase
EIO66_RS09790	COG3139	Protein of unknown function (DUF1315)
EIO66_RS09815	COG0656	L-ascorbic acid biosynthetic process
EIO66_RS09820	COG0641	radical SAM
EIO66_RS09825	COG3713	MltA-interacting MipA family protein
EIO66_RS09830	COG2766	serine protein kinase
EIO66_RS09845	COG3039	Transposase
EIO66_RS09850	COG2199	diguanylate cyclase activity
EIO66_RS09855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EIO66_RS09870	COG2207	Transcriptional regulator
EIO66_RS09875	COG2807	transmembrane transport
EIO66_RS09880	COG3189	MarR family transcriptional regulator
EIO66_RS09890	COG3042	response to heat
EIO66_RS09900	COG2261	transglycosylase associated protein
EIO66_RS09920	COG3615	Tellurite resistance protein tehB
EIO66_RS09930	COG1605	Chorismate mutase
EIO66_RS09940	COG0789	Transcriptional regulator
EIO66_RS09955	COG3443	Belongs to the bacterial solute-binding protein 9 family
EIO66_RS09970	COG0668	transmembrane transport
EIO66_RS09975	COG1124	(ABC) transporter
EIO66_RS09990	COG0601	transmembrane transport
EIO66_RS10005	COG3038	cytochrome b561
EIO66_RS10020	COG0071	Belongs to the small heat shock protein (HSP20) family
EIO66_RS10040	COG3039	Transposase
EIO66_RS10095	COG3039	Transposase
EIO66_RS10125	COG0538	isocitrate dehydrogenase activity
EIO66_RS10130	COG2135	peptidase activity
EIO66_RS10150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EIO66_RS10165	COG3778	Protein conserved in bacteria
EIO66_RS10170	COG3299	homolog of phage Mu protein gp47
EIO66_RS10210	COG4386	tail sheath protein
EIO66_RS10250	COG0740	serine-type endopeptidase activity
EIO66_RS10255	COG4695	Portal protein
EIO66_RS10260	COG1802	Transcriptional regulator
EIO66_RS10260	COG4626	Terminase
EIO66_RS10285	COG3179	chitinase
EIO66_RS10305	COG0484	heat shock protein binding
EIO66_RS10310	COG1403	HNH endonuclease
EIO66_RS10320	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EIO66_RS10325	COG4725	Belongs to the MT-A70-like family
EIO66_RS10335	COG1846	Transcriptional regulator
EIO66_RS10345	COG3646	Phage regulatory protein
EIO66_RS10375	COG5532	Uncharacterized conserved protein (DUF2303)
EIO66_RS10380	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EIO66_RS10390	COG0582	viral genome integration into host DNA
EIO66_RS10395	COG0538	isocitrate dehydrogenase activity
EIO66_RS10425	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EIO66_RS10440	COG2850	peptidyl-arginine hydroxylation
EIO66_RS10470	COG1177	transmembrane transport
EIO66_RS10490	COG4591	ABC-type transport system involved in lipoprotein release permease component
EIO66_RS10495	COG1136	(ABC) transporter
EIO66_RS10500	COG4591	ABC-type transport system involved in lipoprotein release permease component
EIO66_RS10505	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EIO66_RS10510	COG1388	LysM domain
EIO66_RS10510	COG1376	ErfK ybiS ycfS ynhG family protein
EIO66_RS10520	COG1309	transcriptional regulator
EIO66_RS10525	COG3134	Outer membrane lipoprotein
EIO66_RS10530	COG1252	NADH dehydrogenase
EIO66_RS10555	COG5633	Lipoprotein
EIO66_RS10560	COG0537	adenosine 5'-monophosphoramidase activity
EIO66_RS10565	COG4773	Receptor
EIO66_RS10575	COG0084	hydrolase, TatD family'
EIO66_RS10580	COG0470	DNA polymerase III
EIO66_RS10590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EIO66_RS10595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EIO66_RS10600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EIO66_RS10665	COG1530	ribonuclease E activity
EIO66_RS10755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EIO66_RS10765	COG2999	glutathione oxidoreductase activity
EIO66_RS10800	COG3038	cytochrome b561
EIO66_RS10815	COG1560	Kdo2-lipid A biosynthetic process
EIO66_RS10830	COG5645	(Lipo)protein
EIO66_RS10835	COG2943	transferase activity, transferring hexosyl groups
EIO66_RS10855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EIO66_RS10910	COG3381	protein complex oligomerization
EIO66_RS11000	COG3039	Transposase
EIO66_RS11045	COG0582	viral genome integration into host DNA
EIO66_RS11125	COG2916	Histone family protein nucleoid-structuring protein H-NS
EIO66_RS11160	COG3039	Transposase
EIO66_RS11210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EIO66_RS11235	COG0534	Mate efflux family protein
EIO66_RS11250	COG0798	PFAM Bile acid sodium symporter
EIO66_RS11265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EIO66_RS11270	COG0640	Transcriptional regulator
EIO66_RS11305	COG1122	ATPase activity
EIO66_RS11435	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EIO66_RS11465	COG1454	alcohol dehydrogenase
EIO66_RS11465	COG1012	belongs to the aldehyde dehydrogenase family
EIO66_RS11470	COG4656	Part of a membrane complex involved in electron transport
EIO66_RS11505	COG1289	transmembrane transporter activity
EIO66_RS11545	COG2925	Exonuclease
EIO66_RS11550	COG0531	amino acid
EIO66_RS11560	COG0583	DNA-binding transcription factor activity
EIO66_RS11565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIO66_RS11705	COG2327	Polysaccharide pyruvyl transferase
EIO66_RS11710	COG2244	polysaccharide biosynthetic process
EIO66_RS11715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIO66_RS11730	COG0297	glycogen (starch) synthase activity
EIO66_RS11740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIO66_RS11745	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EIO66_RS11750	COG0110	maltose O-acetyltransferase activity
EIO66_RS11755	COG1216	Glycosyl transferase, family 2
EIO66_RS11765	COG0438	transferase activity, transferring glycosyl groups
EIO66_RS11770	COG1045	serine acetyltransferase
EIO66_RS11775	COG0463	Glycosyl transferase, family 2
EIO66_RS11795	COG1253	flavin adenine dinucleotide binding
EIO66_RS11800	COG2982	Protein involved in outer membrane biogenesis
EIO66_RS11815	COG5001	Diguanylate cyclase
EIO66_RS11815	COG5002	protein histidine kinase activity
EIO66_RS11815	COG3447	MASE1 domain protein
EIO66_RS11820	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EIO66_RS11825	COG0443	Heat shock 70 kDa protein
EIO66_RS11855	COG2205	protein histidine kinase activity
EIO66_RS11860	COG0745	RESPONSE REGULATOR receiver
EIO66_RS11970	COG1830	Aldolase
EIO66_RS11975	COG2211	Major facilitator Superfamily
EIO66_RS11980	COG1397	ADP-ribosylglycohydrolase
EIO66_RS11985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIO66_RS11990	COG2188	Transcriptional regulator
EIO66_RS12005	COG5455	response to cobalt ion
EIO66_RS12010	COG3539	Fimbrial protein
EIO66_RS12015	COG3188	usher protein
EIO66_RS12020	COG3121	Chaperone
EIO66_RS12030	COG3039	Transposase
EIO66_RS12055	COG4808	Protein conserved in bacteria
EIO66_RS12065	COG4807	Protein conserved in bacteria
EIO66_RS12075	COG3275	phosphorelay sensor kinase activity
EIO66_RS12090	COG1174	glycine betaine transport
EIO66_RS12095	COG1125	glycine betaine transport
EIO66_RS12100	COG1174	glycine betaine transport
EIO66_RS12105	COG1732	Glycine betaine
EIO66_RS12115	COG0277	FAD linked oxidase domain protein
EIO66_RS12120	COG1686	Belongs to the peptidase S11 family
EIO66_RS12130	COG0586	Pfam SNARE associated Golgi protein
EIO66_RS12135	COG1028	Short-chain dehydrogenase reductase Sdr
EIO66_RS12140	COG1538	Outer membrane efflux protein
EIO66_RS12155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIO66_RS12160	COG0625	glutathione transferase activity
EIO66_RS12175	COG2271	Major facilitator Superfamily
EIO66_RS12190	COG1346	cytolysis
EIO66_RS12200	COG2949	membrane
EIO66_RS12240	COG2311	Membrane
EIO66_RS12260	COG1760	l-serine dehydratase
EIO66_RS12265	COG0560	Phosphoserine phosphatase
EIO66_RS12270	COG2271	Major facilitator Superfamily
EIO66_RS12275	COG4771	TonB-dependent receptor
EIO66_RS12285	COG0833	amino acid
EIO66_RS12290	COG0583	DNA-binding transcription factor activity
EIO66_RS12295	COG2855	membrane
EIO66_RS12305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EIO66_RS12305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EIO66_RS12305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EIO66_RS12310	COG1105	Belongs to the carbohydrate kinase PfkB family
EIO66_RS12345	COG0523	cobalamin synthesis protein
EIO66_RS12350	COG0671	phosphoesterase, PA-phosphatase related
EIO66_RS12355	COG0791	NLP P60 protein
EIO66_RS12360	COG2200	EAL domain
EIO66_RS12365	COG4166	transmembrane transport
EIO66_RS12370	COG4174	ABC transporter (Permease)
EIO66_RS12375	COG4239	(ABC) transporter, permease
EIO66_RS12380	COG4172	Belongs to the ABC transporter superfamily
EIO66_RS12390	COG2814	Major facilitator Superfamily
EIO66_RS12400	COG1061	Type III restriction enzyme res subunit
EIO66_RS12455	COG2197	response regulator
EIO66_RS12460	COG4235	cytochrome complex assembly
EIO66_RS12460	COG3088	subunit of a heme lyase
EIO66_RS12465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIO66_RS12470	COG1138	Cytochrome C-type biogenesis protein
EIO66_RS12480	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIO66_RS12485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIO66_RS12500	COG3005	denitrification pathway
EIO66_RS12505	COG3043	anaerobic respiration
EIO66_RS12510	COG0348	domain, Protein
EIO66_RS12515	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS12525	COG3062	negative regulation of establishment of protein localization
EIO66_RS12530	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIO66_RS12530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIO66_RS12540	COG4615	Cyclic peptide transporter
EIO66_RS12565	COG0642	Histidine kinase
EIO66_RS12565	COG2198	Histidine kinase
EIO66_RS12585	COG4948	Mandelate Racemase Muconate Lactonizing
EIO66_RS12615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIO66_RS12620	COG2814	Major facilitator Superfamily
EIO66_RS12625	COG0583	DNA-binding transcription factor activity
EIO66_RS12635	COG3039	Transposase
EIO66_RS12645	COG0584	glycerophosphoryl diester phosphodiesterase
EIO66_RS12650	COG2271	Major facilitator Superfamily
EIO66_RS12655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EIO66_RS12665	COG0247	lactate metabolic process
EIO66_RS12690	COG2271	Major facilitator Superfamily
EIO66_RS12700	COG1414	Transcriptional regulator
EIO66_RS12790	COG1169	isochorismate synthase
EIO66_RS12795	COG4575	ribosome binding
EIO66_RS12800	COG2153	protein acetylation
EIO66_RS12810	COG0835	chemotaxis
EIO66_RS12810	COG0784	Response regulator, receiver
EIO66_RS12815	COG2304	oxidoreductase activity
EIO66_RS12835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIO66_RS12840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EIO66_RS12850	COG0839	Belongs to the complex I subunit 6 family
EIO66_RS12900	COG0583	DNA-binding transcription factor activity
EIO66_RS12905	COG3039	Transposase
EIO66_RS12915	COG0436	Aminotransferase
EIO66_RS12925	COG0471	metal ion transport
EIO66_RS12925	COG0490	domain, Protein
EIO66_RS12930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIO66_RS12960	COG1288	antiporter activity
EIO66_RS12965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EIO66_RS12970	COG3959	Transketolase, thiamine diphosphate binding domain
EIO66_RS12975	COG3037	sugar-specific permease SgaT UlaA
EIO66_RS12985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS12995	COG1609	Transcriptional regulator
EIO66_RS13005	COG0622	Phosphoesterase
EIO66_RS13010	COG0625	glutathione transferase activity
EIO66_RS13015	COG0625	glutathione transferase activity
EIO66_RS13020	COG1090	epimerase
EIO66_RS13060	COG0833	amino acid
EIO66_RS13065	COG3457	Alanine racemase
EIO66_RS13070	COG0531	amino acid
EIO66_RS13080	COG3829	transcription factor binding
EIO66_RS13085	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EIO66_RS13090	COG1286	toxin biosynthetic process
EIO66_RS13095	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EIO66_RS13100	COG0285	dihydrofolate synthase activity
EIO66_RS13110	COG0586	Pfam SNARE associated Golgi protein
EIO66_RS13120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EIO66_RS13160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EIO66_RS13175	COG3101	peptidyl-lysine hydroxylation
EIO66_RS13180	COG0730	response to heat
EIO66_RS13205	COG2062	phosphohistidine phosphatase, SixA
EIO66_RS13220	COG3691	Protein conserved in bacteria
EIO66_RS13235	COG2116	formate transmembrane transporter activity
EIO66_RS13245	COG0582	viral genome integration into host DNA
EIO66_RS13355	COG0740	serine-type endopeptidase activity
EIO66_RS13360	COG4695	Portal protein
EIO66_RS13365	COG4626	Terminase
EIO66_RS13365	COG1802	Transcriptional regulator
EIO66_RS13415	COG3772	lysozyme
EIO66_RS13430	COG0484	heat shock protein binding
EIO66_RS13475	COG0305	Participates in initiation and elongation during chromosome replication
EIO66_RS13535	COG4712	double-strand break repair protein
EIO66_RS13620	COG1560	Kdo2-lipid A biosynthetic process
EIO66_RS13630	COG0436	Aminotransferase
EIO66_RS13645	COG3961	Belongs to the TPP enzyme family
EIO66_RS13650	COG0667	Aldo Keto reductase
EIO66_RS13665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EIO66_RS13670	COG2200	EAL domain
EIO66_RS13670	COG2199	diguanylate cyclase activity
EIO66_RS13685	COG3415	Transposase
EIO66_RS13690	COG3415	Transposase
EIO66_RS13720	COG0583	DNA-binding transcription factor activity
EIO66_RS13730	COG2211	Major facilitator Superfamily
EIO66_RS13735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EIO66_RS13745	COG0583	DNA-binding transcription factor activity
EIO66_RS13750	COG0385	Bile acid
EIO66_RS13755	COG3530	Putative quorum-sensing-regulated virulence factor
EIO66_RS13780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS13825	COG3039	Transposase
EIO66_RS13850	COG4208	sulfate ABC transporter
EIO66_RS13870	COG2837	iron assimilation
EIO66_RS14005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EIO66_RS14015	COG5342	invasion associated locus B
EIO66_RS14030	COG0493	'glutamate synthase
EIO66_RS14030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIO66_RS14035	COG3850	Histidine kinase
EIO66_RS14040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EIO66_RS14050	COG1393	Belongs to the ArsC family
EIO66_RS14070	COG2321	neutral zinc metallopeptidase
EIO66_RS14080	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EIO66_RS14090	COG2716	regulation of RNA biosynthetic process
EIO66_RS14095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EIO66_RS14100	COG1929	Belongs to the glycerate kinase type-1 family
EIO66_RS14105	COG2610	gluconate transmembrane transporter activity
EIO66_RS14110	COG3835	regulator
EIO66_RS14115	COG0628	permease
EIO66_RS14125	COG1393	Belongs to the ArsC family
EIO66_RS14135	COG2233	PERMEase
EIO66_RS14150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EIO66_RS14165	COG2200	EAL domain
EIO66_RS14180	COG3133	Outer membrane lipoprotein
EIO66_RS14215	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EIO66_RS14270	COG0582	viral genome integration into host DNA
EIO66_RS14280	COG0517	IMP dehydrogenase activity
EIO66_RS14280	COG0516	GMP reductase activity
EIO66_RS14315	COG1645	bacterial-type flagellum-dependent swarming motility
EIO66_RS14330	COG2976	Protein conserved in bacteria
EIO66_RS14370	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS14375	COG0243	molybdopterin cofactor binding
EIO66_RS14380	COG4953	penicillin-binding protein 1C
EIO66_RS14385	COG2373	Large extracellular alpha-helical protein
EIO66_RS14390	COG2897	thiosulfate sulfurtransferase activity
EIO66_RS14420	COG2975	iron-sulfur cluster assembly
EIO66_RS14425	COG0633	Ferredoxin
EIO66_RS14445	COG0822	iron-sulfur transferase activity
EIO66_RS14490	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EIO66_RS14500	COG3711	transcriptional antiterminator
EIO66_RS14505	COG2814	Major facilitator Superfamily
EIO66_RS14515	COG1017	nitric oxide dioxygenase activity
EIO66_RS14515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIO66_RS14520	COG3710	Transcriptional regulator
EIO66_RS14525	COG0531	amino acid
EIO66_RS14535	COG3104	oligopeptide transport
EIO66_RS14540	COG0347	Belongs to the P(II) protein family
EIO66_RS14545	COG2204	response regulator
EIO66_RS14550	COG3170	Tfp pilus assembly protein FimV
EIO66_RS14555	COG2205	protein histidine kinase activity
EIO66_RS14580	COG0560	Phosphoserine phosphatase
EIO66_RS14585	COG1263	PTS System
EIO66_RS14585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIO66_RS14595	COG1737	Transcriptional regulator
EIO66_RS14600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EIO66_RS14605	COG2223	nitrite transmembrane transporter activity
EIO66_RS14610	COG0583	DNA-binding transcription factor activity
EIO66_RS14615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIO66_RS14660	COG3086	response to oxidative stress
EIO66_RS14690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EIO66_RS14700	COG0513	Belongs to the DEAD box helicase family
EIO66_RS14705	COG0583	DNA-binding transcription factor activity
EIO66_RS14725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIO66_RS14730	COG3118	belongs to the thioredoxin family
EIO66_RS14745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EIO66_RS14750	COG5544	Lipoprotein
EIO66_RS14755	COG0477	Major facilitator Superfamily
EIO66_RS14790	COG0542	response to heat
EIO66_RS14805	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EIO66_RS14810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EIO66_RS14820	COG1196	nuclear chromosome segregation
EIO66_RS14845	COG5301	cellulose 1,4-beta-cellobiosidase activity
EIO66_RS14940	COG4695	Portal protein
EIO66_RS14980	COG4974	Belongs to the 'phage' integrase family
EIO66_RS14990	COG0077	Prephenate dehydratase
EIO66_RS14990	COG1605	Chorismate mutase
EIO66_RS15000	COG0287	Prephenate dehydrogenase
EIO66_RS15000	COG1605	Chorismate mutase
EIO66_RS15015	COG2199	diguanylate cyclase activity
EIO66_RS15040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EIO66_RS15050	COG4137	Cytochrome C assembly protein
EIO66_RS15055	COG4536	flavin adenine dinucleotide binding
EIO66_RS15080	COG0497	DNA recombination
EIO66_RS15095	COG2867	negative regulation of translational initiation
EIO66_RS15120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIO66_RS15130	COG0582	viral genome integration into host DNA
EIO66_RS15145	COG3311	Transcriptional regulator
EIO66_RS15155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EIO66_RS15165	COG1061	Type III restriction enzyme res subunit
EIO66_RS15175	COG0789	Transcriptional regulator
EIO66_RS15205	COG2375	cellular response to nickel ion
EIO66_RS15220	COG1461	Dihydroxyacetone kinase
EIO66_RS15225	COG2376	Dihydroxyacetone kinase
EIO66_RS15320	COG3039	Transposase
EIO66_RS15325	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EIO66_RS15330	COG1061	Type III restriction enzyme res subunit
EIO66_RS15335	COG1002	Type II restriction enzyme, methylase subunits
EIO66_RS15355	COG3596	GTP binding
EIO66_RS15365	COG2378	regulation of single-species biofilm formation
EIO66_RS15375	COG2378	regulation of single-species biofilm formation
EIO66_RS15415	COG2003	Belongs to the UPF0758 family
EIO66_RS15455	COG0582	viral genome integration into host DNA
EIO66_RS15500	COG2819	hydrolase of the alpha beta superfamily
EIO66_RS15525	COG2990	Protein conserved in bacteria
EIO66_RS15540	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EIO66_RS15545	COG0642	Histidine kinase
EIO66_RS15575	COG0579	oxidoreductase
EIO66_RS15580	COG1012	belongs to the aldehyde dehydrogenase family
EIO66_RS15585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EIO66_RS15590	COG1113	amino acid transport
EIO66_RS15595	COG1802	Transcriptional regulator
EIO66_RS15600	COG1652	LysM domain
EIO66_RS15610	COG0401	homolog of Blt101
EIO66_RS15615	COG0640	Transcriptional regulator
EIO66_RS15620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIO66_RS15650	COG4575	ribosome binding
EIO66_RS15660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EIO66_RS15710	COG2814	Major facilitator Superfamily
EIO66_RS15715	COG1846	Transcriptional regulator
EIO66_RS15720	COG1566	PFAM secretion protein HlyD family protein
EIO66_RS15725	COG2814	Major facilitator Superfamily
EIO66_RS15745	COG1238	metal cluster binding
EIO66_RS15750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIO66_RS15780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EIO66_RS15805	COG1546	Belongs to the CinA family
EIO66_RS15815	COG2951	lytic endotransglycosylase activity
EIO66_RS15820	COG3730	PTS system glucitol sorbitol-specific
EIO66_RS15825	COG3732	PTS system glucitol sorbitol-specific
EIO66_RS15830	COG3731	PTS system glucitol sorbitol-specific IIA component
EIO66_RS15835	COG1028	Short-chain dehydrogenase reductase Sdr
EIO66_RS15840	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS15845	COG1349	DNA-binding transcription factor activity
EIO66_RS15850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EIO66_RS15850	COG0517	IMP dehydrogenase activity
EIO66_RS15865	COG0446	pyridine nucleotide-disulphide oxidoreductase
EIO66_RS15870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EIO66_RS15875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIO66_RS15885	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EIO66_RS15895	COG3260	NADH ubiquinone oxidoreductase 20
EIO66_RS15900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIO66_RS15905	COG3261	NADH dehydrogenase
EIO66_RS15905	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EIO66_RS15910	COG0650	Formate hydrogenlyase subunit 4
EIO66_RS15915	COG0651	ATP synthesis coupled electron transport
EIO66_RS15920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIO66_RS15940	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EIO66_RS15945	COG0298	carbon dioxide binding
EIO66_RS15950	COG0409	Hydrogenase expression formation protein
EIO66_RS15955	COG0309	Hydrogenase expression formation protein (HypE)
EIO66_RS15975	COG1121	(ABC) transporter
EIO66_RS15980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EIO66_RS15990	COG3039	Transposase
EIO66_RS16030	COG3436	PFAM IS66 Orf2 family protein
EIO66_RS16040	COG3344	reverse transcriptase
EIO66_RS16055	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EIO66_RS16060	COG3586	endonuclease activity
EIO66_RS16070	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EIO66_RS16090	COG4974	Belongs to the 'phage' integrase family
EIO66_RS16110	COG2003	Belongs to the UPF0758 family
EIO66_RS16125	COG3423	Transcriptional regulator
EIO66_RS16165	COG0477	Major facilitator Superfamily
EIO66_RS16175	COG2610	gluconate transmembrane transporter activity
EIO66_RS16180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIO66_RS16185	COG3622	Belongs to the hyi family
EIO66_RS16190	COG0235	Class ii aldolase
EIO66_RS16200	COG2084	Dehydrogenase
EIO66_RS16205	COG1349	DNA-binding transcription factor activity
EIO66_RS16215	COG0163	prenyltransferase activity
EIO66_RS16220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EIO66_RS16290	COG2234	aminopeptidase activity
EIO66_RS16295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EIO66_RS16300	COG1518	maintenance of DNA repeat elements
EIO66_RS16315	COG1857	crispr-associated protein
EIO66_RS16330	COG1203	CRISPR-associated helicase, Cas3
EIO66_RS16355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EIO66_RS16365	COG0720	synthase
EIO66_RS16370	COG0321	lipoyl(octanoyl) transferase activity
EIO66_RS16370	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EIO66_RS16375	COG0602	queuosine metabolic process
EIO66_RS16390	COG3956	TIGRFAM MazG family protein
EIO66_RS16395	COG3539	Fimbrial protein
EIO66_RS16400	COG3188	usher protein
EIO66_RS16405	COG3121	Chaperone
EIO66_RS16410	COG3539	Fimbrial protein
EIO66_RS16445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIO66_RS16455	COG4999	Histidine kinase
EIO66_RS16455	COG3850	Histidine kinase
EIO66_RS16455	COG2205	protein histidine kinase activity
EIO66_RS16455	COG3437	response regulator, receiver
EIO66_RS16460	COG1929	Belongs to the glycerate kinase type-1 family
EIO66_RS16465	COG4948	Mandelate Racemase Muconate Lactonizing
EIO66_RS16470	COG4948	Mandelate Racemase Muconate Lactonizing
EIO66_RS16475	COG2271	Major facilitator Superfamily
EIO66_RS16485	COG0716	FMN binding
EIO66_RS16495	COG3098	single-species biofilm formation
EIO66_RS16515	COG1611	Belongs to the LOG family
EIO66_RS16520	COG0814	amino acid
EIO66_RS16525	COG1760	l-serine dehydratase
EIO66_RS16540	COG1454	alcohol dehydrogenase
EIO66_RS16545	COG0235	Class ii aldolase
EIO66_RS16550	COG0738	Major facilitator superfamily
EIO66_RS16570	COG1349	DNA-binding transcription factor activity
EIO66_RS16580	COG2363	Small membrane protein
EIO66_RS16585	COG0583	DNA-binding transcription factor activity
EIO66_RS16595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EIO66_RS16600	COG2166	iron-sulfur cluster assembly
EIO66_RS16605	COG2962	Rard protein
EIO66_RS16610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EIO66_RS16615	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EIO66_RS16630	COG0860	N-Acetylmuramoyl-L-alanine amidase
EIO66_RS16640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EIO66_RS16645	COG1074	ATP-dependent DNA helicase activity
EIO66_RS16655	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EIO66_RS16660	COG4967	type IV pilus modification protein PilV
EIO66_RS16670	COG4795	General secretion pathway protein
EIO66_RS16675	COG2165	general secretion pathway protein
EIO66_RS16710	COG0861	Integral membrane protein TerC family
EIO66_RS16720	COG0667	Aldo Keto reductase
EIO66_RS16750	COG1609	Transcriptional regulator
EIO66_RS16760	COG0583	DNA-binding transcription factor activity
EIO66_RS16765	COG1794	racemase activity, acting on amino acids and derivatives
EIO66_RS16770	COG2814	Major facilitator Superfamily
EIO66_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
EIO66_RS16790	COG0183	Belongs to the thiolase family
EIO66_RS16805	COG0814	amino acid
EIO66_RS16840	COG3188	usher protein
EIO66_RS16880	COG4942	peptidase
EIO66_RS16945	COG1272	protein, Hemolysin III
EIO66_RS16955	COG2723	6-phospho-beta-galactosidase activity
EIO66_RS16985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIO66_RS16990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIO66_RS16995	COG0006	proline dipeptidase activity
EIO66_RS17015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EIO66_RS17020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EIO66_RS17040	COG2968	Membrane
EIO66_RS17050	COG0668	transmembrane transport
EIO66_RS17055	COG0191	fructose-bisphosphate aldolase activity
EIO66_RS17090	COG1122	ATPase activity
EIO66_RS17095	COG1122	ATPase activity
EIO66_RS17100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EIO66_RS17105	COG0501	Belongs to the peptidase M48B family
EIO66_RS17120	COG2731	YhcH YjgK YiaL family protein
EIO66_RS17125	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EIO66_RS17130	COG1063	alcohol dehydrogenase
EIO66_RS17135	COG0246	Mannitol dehydrogenase
EIO66_RS17145	COG2186	Transcriptional regulator
EIO66_RS17155	COG3039	Transposase
EIO66_RS17160	COG1166	arginine decarboxylase activity
EIO66_RS17185	COG2814	Major facilitator Superfamily
EIO66_RS17195	COG2356	endonuclease I
EIO66_RS17200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EIO66_RS17225	COG2805	Type II/IV secretion system protein
EIO66_RS17230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EIO66_RS17235	COG0762	integral membrane protein
EIO66_RS17250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EIO66_RS17260	COG0252	asparaginase activity
EIO66_RS17270	COG3171	Protein conserved in bacteria
EIO66_RS17295	COG2211	Major facilitator Superfamily
EIO66_RS17300	COG1982	Orn Lys Arg decarboxylase major
EIO66_RS17305	COG1811	Na channel or pump
EIO66_RS17325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EIO66_RS17335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIO66_RS17370	COG3039	Transposase
EIO66_RS17475	COG0531	amino acid
EIO66_RS17485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIO66_RS17490	COG1012	belongs to the aldehyde dehydrogenase family
EIO66_RS17520	COG2271	Major facilitator Superfamily
EIO66_RS17530	COG0246	Mannitol dehydrogenase
EIO66_RS17550	COG0754	glutathionylspermidine amidase activity
EIO66_RS17555	COG0625	glutathione transferase activity
EIO66_RS17570	COG0298	carbon dioxide binding
EIO66_RS17580	COG1773	rubredoxin
EIO66_RS17585	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EIO66_RS17590	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EIO66_RS17595	COG5557	Pfam Polysulphide reductase, NrfD
EIO66_RS17600	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS17605	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EIO66_RS17615	COG0840	transmembrane signaling receptor activity
EIO66_RS17640	COG1028	Short-chain dehydrogenase reductase Sdr
EIO66_RS17645	COG0848	biopolymer transport protein
EIO66_RS17665	COG2207	Transcriptional regulator
EIO66_RS17670	COG1979	alcohol dehydrogenase
EIO66_RS17680	COG0471	metal ion transport
EIO66_RS17735	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EIO66_RS17740	COG3111	PFAM Bacterial OB fold (BOF) protein
EIO66_RS17750	COG0642	Histidine kinase
EIO66_RS17755	COG2249	NAD(P)H dehydrogenase (quinone) activity
EIO66_RS17760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EIO66_RS17770	COG3150	esterase
EIO66_RS17775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EIO66_RS17780	COG3151	Protein conserved in bacteria
EIO66_RS17785	COG0494	nUDIX hydrolase
EIO66_RS17800	COG0754	glutathionylspermidine amidase activity
EIO66_RS17805	COG3384	dioxygenase
EIO66_RS17845	COG1585	Membrane protein implicated in regulation of membrane protease activity
EIO66_RS17850	COG2268	Band 7 protein
EIO66_RS17870	COG3025	triphosphatase activity
EIO66_RS17875	COG4991	sh3 domain protein
EIO66_RS17890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EIO66_RS17910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EIO66_RS17935	COG2375	cellular response to nickel ion
EIO66_RS17940	COG1695	Transcriptional regulator
EIO66_RS17945	COG0840	transmembrane signaling receptor activity
EIO66_RS18045	COG1566	PFAM secretion protein HlyD family protein
EIO66_RS18050	COG1289	transmembrane transporter activity
EIO66_RS18075	COG3344	reverse transcriptase
EIO66_RS18120	COG3039	Transposase
EIO66_RS18165	COG1482	cell wall glycoprotein biosynthetic process
EIO66_RS18230	COG1585	Membrane protein implicated in regulation of membrane protease activity
EIO66_RS18265	COG0840	transmembrane signaling receptor activity
EIO66_RS18275	COG0446	pyridine nucleotide-disulphide oxidoreductase
EIO66_RS18275	COG1902	pentaerythritol trinitrate reductase activity
EIO66_RS18285	COG1451	nucleotide metabolic process
EIO66_RS18290	COG2949	membrane
EIO66_RS18295	COG0673	inositol 2-dehydrogenase activity
EIO66_RS18310	COG0586	Pfam SNARE associated Golgi protein
EIO66_RS18320	COG1422	Protein of unknown function (DUF1090)
EIO66_RS18325	COG4575	ribosome binding
EIO66_RS18330	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EIO66_RS18340	COG2259	Doxx family
EIO66_RS18345	COG0435	Glutathione S-transferase
EIO66_RS18350	COG3152	Membrane
EIO66_RS18355	COG0583	DNA-binding transcription factor activity
EIO66_RS18360	COG1741	Belongs to the pirin family
EIO66_RS18375	COG0814	amino acid
EIO66_RS18380	COG1760	l-serine dehydratase
EIO66_RS18385	COG1882	Formate acetyltransferase
EIO66_RS18405	COG0583	DNA-binding transcription factor activity
EIO66_RS18425	COG1929	Belongs to the glycerate kinase type-1 family
EIO66_RS18430	COG2084	Dehydrogenase
EIO66_RS18440	COG2721	sulfolactate sulfo-lyase activity
EIO66_RS18455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS18460	COG3414	Phosphotransferase system galactitol-specific IIB component
EIO66_RS18465	COG3775	system Galactitol-specific IIC component
EIO66_RS18470	COG1063	alcohol dehydrogenase
EIO66_RS18480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EIO66_RS18485	COG3107	peptidoglycan biosynthetic process
EIO66_RS18500	COG2823	Periplasmic or secreted lipoprotein
EIO66_RS18505	COG0702	epimerase
EIO66_RS18510	COG0693	protein deglycase activity
EIO66_RS18525	COG3153	acetyltransferase
EIO66_RS18530	COG3154	lipid carrier protein
EIO66_RS18535	COG0826	peptidase U32
EIO66_RS18540	COG0826	peptidase U32
EIO66_RS18545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIO66_RS18550	COG3034	peptidoglycan biosynthetic process
EIO66_RS18560	COG0814	amino acid
EIO66_RS18565	COG0513	Belongs to the DEAD box helicase family
EIO66_RS18635	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EIO66_RS18645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EIO66_RS18660	COG1534	Rna-binding protein
EIO66_RS18670	COG2027	D-alanyl-D-alanine carboxypeptidase
EIO66_RS18680	COG0697	spore germination
EIO66_RS18695	COG0142	geranyltranstransferase activity
EIO66_RS18700	COG3423	Transcriptional regulator
EIO66_RS18710	COG5007	Belongs to the BolA IbaG family
EIO66_RS18715	COG3113	response to antibiotic
EIO66_RS18720	COG2854	intermembrane phospholipid transfer
EIO66_RS18725	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EIO66_RS18730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EIO66_RS18735	COG1127	ABC transporter
EIO66_RS18740	COG0530	calcium, potassium:sodium antiporter activity
EIO66_RS18750	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EIO66_RS18755	COG3117	lipopolysaccharide transmembrane transporter activity
EIO66_RS18760	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EIO66_RS18765	COG1137	ATPase activity
EIO66_RS18790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS18800	COG0515	serine threonine protein kinase
EIO66_RS18810	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EIO66_RS18815	COG5002	protein histidine kinase activity
EIO66_RS18815	COG2198	Histidine kinase
EIO66_RS18815	COG0784	Response regulator, receiver
EIO66_RS18820	COG1242	4 iron, 4 sulfur cluster binding
EIO66_RS18825	COG0070	glutamate synthase
EIO66_RS18825	COG0067	glutamate synthase
EIO66_RS18825	COG0069	glutamate synthase activity
EIO66_RS18830	COG0493	'glutamate synthase
EIO66_RS18835	COG4804	nuclease activity
EIO66_RS18840	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EIO66_RS18845	COG0402	S-adenosylhomocysteine deaminase activity
EIO66_RS18850	COG2731	YhcH YjgK YiaL family protein
EIO66_RS18855	COG1940	carbohydrate kinase activity
EIO66_RS18880	COG2969	positive regulation of protein catabolic process
EIO66_RS18885	COG0625	glutathione transferase activity
EIO66_RS18905	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EIO66_RS18910	COG3105	Protein conserved in bacteria
EIO66_RS18915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIO66_RS18930	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EIO66_RS18935	COG0511	ligase activity, forming carbon-carbon bonds
EIO66_RS18935	COG5016	pyruvate
EIO66_RS18945	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EIO66_RS18950	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EIO66_RS18955	COG0471	metal ion transport
EIO66_RS18965	COG2188	Transcriptional regulator
EIO66_RS18990	COG2732	(Barnase) inhibitor
EIO66_RS19010	COG0583	DNA-binding transcription factor activity
EIO66_RS19015	COG0312	modulator of DNA gyrase
EIO66_RS19020	COG3164	Protein of unknown function
EIO66_RS19025	COG1530	ribonuclease E activity
EIO66_RS19035	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EIO66_RS19040	COG1792	Involved in formation and maintenance of cell shape
EIO66_RS19045	COG1077	Cell shape determining protein MreB Mrl
EIO66_RS19055	COG2200	EAL domain
EIO66_RS19055	COG2199	diguanylate cyclase activity
EIO66_RS19060	COG0604	alcohol dehydrogenase
EIO66_RS19075	COG0511	ligase activity, forming carbon-carbon bonds
EIO66_RS19080	COG0439	Biotin carboxylase
EIO66_RS19085	COG3924	membrane
EIO66_RS19090	COG4145	pantothenate transmembrane transporter activity
EIO66_RS19110	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EIO66_RS19125	COG1309	transcriptional regulator
EIO66_RS19130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIO66_RS19135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EIO66_RS19175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EIO66_RS19195	COG0551	DNA topoisomerase type I activity
EIO66_RS19205	COG0758	DNA mediated transformation
EIO66_RS19235	COG3036	rescue of stalled ribosome
EIO66_RS19240	COG0789	Transcriptional regulator
EIO66_RS19280	COG0201	protein transport
EIO66_RS19360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EIO66_RS19385	COG0051	transcription antitermination factor activity, RNA binding
EIO66_RS19440	COG2964	Protein conserved in bacteria
EIO66_RS19445	COG0545	Peptidyl-prolyl cis-trans isomerase
EIO66_RS19455	COG1047	Peptidyl-prolyl cis-trans
EIO66_RS19460	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EIO66_RS19475	COG0488	(ABC) transporter
EIO66_RS19490	COG0429	hydrolase of the alpha beta-hydrolase fold
EIO66_RS19500	COG3954	Phosphoribulokinase
EIO66_RS19505	COG1765	OsmC-like protein
EIO66_RS19515	COG1289	transmembrane transporter activity
EIO66_RS19550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EIO66_RS19590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EIO66_RS19595	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EIO66_RS19600	COG3266	domain, Protein
EIO66_RS19620	COG4796	Type ii and iii secretion system protein
EIO66_RS19635	COG3166	PFAM Fimbrial assembly family protein
EIO66_RS19640	COG4972	Pilus assembly protein
EIO66_RS19645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EIO66_RS19650	COG0494	nUDIX hydrolase
EIO66_RS19660	COG1011	Hydrolase
EIO66_RS19665	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EIO66_RS19675	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EIO66_RS19690	COG0745	RESPONSE REGULATOR receiver
EIO66_RS19695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EIO66_RS19700	COG2183	response to ionizing radiation
EIO66_RS19705	COG1918	ferrous iron import across plasma membrane
EIO66_RS19720	COG5464	transposase or invertase
EIO66_RS19740	COG2610	gluconate transmembrane transporter activity
EIO66_RS19745	COG1640	4-alpha-glucanotransferase
EIO66_RS19750	COG0058	SHG alpha-glucan phosphorylase activity
EIO66_RS19770	COG1690	Belongs to the RtcB family
EIO66_RS19780	COG4650	regulator
EIO66_RS19785	COG1349	DNA-binding transcription factor activity
EIO66_RS19790	COG0705	Rhomboid family
EIO66_RS19800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EIO66_RS19815	COG0371	Dehydrogenase
EIO66_RS19825	COG0129	dihydroxy-acid dehydratase activity
EIO66_RS19830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EIO66_RS19835	COG1414	Transcriptional regulator
EIO66_RS19840	COG0058	SHG alpha-glucan phosphorylase activity
EIO66_RS19860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EIO66_RS19870	COG2095	MarC family integral membrane protein
EIO66_RS19875	COG2610	gluconate transmembrane transporter activity
EIO66_RS19880	COG3265	gluconokinase activity
EIO66_RS19885	COG1609	Transcriptional regulator
EIO66_RS19890	COG1741	Belongs to the pirin family
EIO66_RS19895	COG0673	inositol 2-dehydrogenase activity
EIO66_RS19900	COG1247	-acetyltransferase
EIO66_RS19905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIO66_RS19920	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EIO66_RS19925	COG0405	Gamma-glutamyltransferase
EIO66_RS19935	COG0584	glycerophosphoryl diester phosphodiesterase
EIO66_RS20010	COG2177	Part of the ABC transporter FtsEX involved in
EIO66_RS20015	COG2884	Cell division ATP-binding protein ftsE
EIO66_RS20020	COG0552	protein localization to endoplasmic reticulum
EIO66_RS20025	COG0742	ribosomal rna small subunit methyltransferase
EIO66_RS20030	COG3776	membrane
EIO66_RS20060	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EIO66_RS20075	COG0628	permease
EIO66_RS20080	COG2091	lysine biosynthetic process via aminoadipic acid
EIO66_RS20090	COG0842	Transport permease protein
EIO66_RS20095	COG0842	Transport permease protein
EIO66_RS20095	COG1129	ABC transporter
EIO66_RS20100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIO66_RS20105	COG2081	HI0933 family
EIO66_RS20110	COG0306	phosphate transporter
EIO66_RS20150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EIO66_RS20155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIO66_RS20175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EIO66_RS20180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIO66_RS20185	COG2222	sugar isomerase
EIO66_RS20190	COG2188	Transcriptional regulator
EIO66_RS20210	COG2197	response regulator
EIO66_RS20215	COG0583	DNA-binding transcription factor activity
EIO66_RS20220	COG1295	ribonuclease BN
EIO66_RS20225	COG0477	Major facilitator Superfamily
EIO66_RS20230	COG2982	Protein involved in outer membrane biogenesis
EIO66_RS20235	COG2200	EAL domain
EIO66_RS20240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIO66_RS20255	COG2200	EAL domain
EIO66_RS20255	COG2199	diguanylate cyclase activity
EIO66_RS20280	COG1215	transferase activity, transferring glycosyl groups
EIO66_RS20320	COG0814	amino acid
EIO66_RS20325	COG4608	Belongs to the ABC transporter superfamily
EIO66_RS20330	COG0444	Belongs to the ABC transporter superfamily
EIO66_RS20335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EIO66_RS20340	COG0601	transmembrane transport
EIO66_RS20345	COG0747	negative chemotaxis
EIO66_RS20360	COG1609	Transcriptional regulator
EIO66_RS20405	COG5571	outer membrane autotransporter
EIO66_RS20410	COG2818	Glycosylase
EIO66_RS20415	COG0456	acetyltransferase
EIO66_RS20420	COG0243	molybdopterin cofactor binding
EIO66_RS20425	COG2885	chlorophyll binding
EIO66_RS20440	COG2944	sequence-specific DNA binding
EIO66_RS20445	COG1278	Cold shock
EIO66_RS20470	COG2801	Transposase and inactivated derivatives
EIO66_RS20495	COG3274	enterobacterial common antigen metabolic process
EIO66_RS20500	COG4682	membrane
EIO66_RS20505	COG1070	Carbohydrate kinase
EIO66_RS20520	COG1609	Transcriptional regulator
EIO66_RS20520	COG2207	Transcriptional regulator
EIO66_RS20525	COG2992	FlgJ-related protein
EIO66_RS20530	COG0366	Alpha amylase catalytic
EIO66_RS20535	COG3977	Valine--pyruvate aminotransferase
EIO66_RS20540	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIO66_RS20545	COG1414	Transcriptional regulator
EIO66_RS20555	COG2731	YhcH YjgK YiaL family protein
EIO66_RS20565	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EIO66_RS20570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EIO66_RS20575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EIO66_RS20580	COG1070	Carbohydrate kinase
EIO66_RS20585	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EIO66_RS20590	COG3623	hexulose-6-phosphate isomerase
EIO66_RS20595	COG0235	Class ii aldolase
EIO66_RS20610	COG1012	belongs to the aldehyde dehydrogenase family
EIO66_RS20615	COG1940	carbohydrate kinase activity
EIO66_RS20620	COG3276	selenocysteine insertion sequence binding
EIO66_RS20630	COG0625	glutathione transferase activity
EIO66_RS20635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS20635	COG2213	PTS system mannitol-specific
EIO66_RS20645	COG3722	fumarate hydratase activity
EIO66_RS20675	COG2186	Transcriptional regulator
EIO66_RS20685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EIO66_RS20690	COG1609	Transcriptional regulator
EIO66_RS20700	COG2271	Major facilitator Superfamily
EIO66_RS20720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EIO66_RS20725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIO66_RS20735	COG4942	peptidase
EIO66_RS20740	COG2861	carbohydrate metabolic process
EIO66_RS20745	COG1216	Glycosyl transferase, family 2
EIO66_RS20820	COG0438	transferase activity, transferring glycosyl groups
EIO66_RS20825	COG0859	PFAM glycosyl transferase family 9
EIO66_RS20830	COG1519	Transferase
EIO66_RS20860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EIO66_RS20885	COG1561	YicC-like family, N-terminal region
EIO66_RS20910	COG3561	AntA/AntB antirepressor
EIO66_RS21000	COG0583	DNA-binding transcription factor activity
EIO66_RS21010	COG2860	membrane
EIO66_RS21030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIO66_RS21035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIO66_RS21040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EIO66_RS21050	COG0786	glutamate:sodium symporter activity
EIO66_RS21055	COG2233	PERMEase
EIO66_RS21060	COG2982	Protein involved in outer membrane biogenesis
EIO66_RS21065	COG1501	Belongs to the glycosyl hydrolase 31 family
EIO66_RS21070	COG2211	Major facilitator Superfamily
EIO66_RS21085	COG2771	luxR family
EIO66_RS21100	COG3710	Transcriptional regulator
EIO66_RS21110	COG1335	isochorismatase
EIO66_RS21140	COG3039	Transposase
EIO66_RS21155	COG5464	transposase or invertase
EIO66_RS21170	COG3716	PTS system mannose fructose sorbose family IID component
EIO66_RS21175	COG3715	PTS system
EIO66_RS21180	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS21180	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIO66_RS21200	COG2723	6-phospho-beta-galactosidase activity
EIO66_RS21250	COG0738	Major facilitator superfamily
EIO66_RS21260	COG1349	DNA-binding transcription factor activity
EIO66_RS21265	COG0440	acetolactate synthase activity
EIO66_RS21270	COG0028	Belongs to the TPP enzyme family
EIO66_RS21295	COG2814	Major facilitator Superfamily
EIO66_RS21305	COG0583	DNA-binding transcription factor activity
EIO66_RS21310	COG2610	gluconate transmembrane transporter activity
EIO66_RS21320	COG0641	radical SAM
EIO66_RS21330	COG2149	membrane
EIO66_RS21350	COG5645	(Lipo)protein
EIO66_RS21355	COG0823	Involved in the tonB-independent uptake of proteins
EIO66_RS21360	COG3088	subunit of a heme lyase
EIO66_RS21360	COG4235	cytochrome complex assembly
EIO66_RS21365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIO66_RS21370	COG1138	Cytochrome C-type biogenesis protein
EIO66_RS21380	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIO66_RS21385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIO66_RS21390	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIO66_RS21400	COG1858	cytochrome C peroxidase
EIO66_RS21415	COG3005	denitrification pathway
EIO66_RS21420	COG0745	RESPONSE REGULATOR receiver
EIO66_RS21425	COG1879	ABC-type sugar transport system periplasmic component
EIO66_RS21430	COG2205	protein histidine kinase activity
EIO66_RS21430	COG2198	Histidine kinase
EIO66_RS21430	COG0784	Response regulator, receiver
EIO66_RS21450	COG0561	phosphatase activity
EIO66_RS21455	COG2271	Major facilitator Superfamily
EIO66_RS21460	COG4948	Mandelate Racemase Muconate Lactonizing
EIO66_RS21545	COG2091	lysine biosynthetic process via aminoadipic acid
EIO66_RS21550	COG0431	NADPH-dependent FMN reductase
EIO66_RS21555	COG2252	PERMEase
EIO66_RS21560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIO66_RS21565	COG0704	Plays a role in the regulation of phosphate uptake
EIO66_RS21575	COG0581	inorganic phosphate transmembrane transporter activity
EIO66_RS21580	COG0573	inorganic phosphate transmembrane transporter activity
EIO66_RS21585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EIO66_RS21590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EIO66_RS21590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EIO66_RS21590	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EIO66_RS21595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EIO66_RS21600	COG4533	DNA binding
EIO66_RS21665	COG3312	ion transport
EIO66_RS21685	COG0716	FMN binding
EIO66_RS21690	COG1522	sequence-specific DNA binding
EIO66_RS21725	COG1172	Belongs to the binding-protein-dependent transport system permease family
EIO66_RS21735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIO66_RS21740	COG1609	Transcriptional regulator
EIO66_RS21745	COG0477	Major facilitator Superfamily
EIO66_RS21750	COG2186	Transcriptional regulator
EIO66_RS21810	COG3978	acetolactate synthase activity
EIO66_RS21885	COG3118	belongs to the thioredoxin family
EIO66_RS21915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EIO66_RS21920	COG1088	dTDP-glucose 4,6-dehydratase activity
EIO66_RS21925	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EIO66_RS21925	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EIO66_RS21930	COG0456	acetyltransferase
EIO66_RS21935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EIO66_RS21940	COG2244	polysaccharide biosynthetic process
EIO66_RS21985	COG3071	HemY protein
EIO66_RS21990	COG2959	enzyme of heme biosynthesis
EIO66_RS22065	COG1011	Hydrolase
EIO66_RS22120	COG1280	lysine exporter protein (LysE YggA)
EIO66_RS22125	COG2267	carboxylic ester hydrolase activity
EIO66_RS22130	COG0561	phosphatase activity
EIO66_RS22155	COG0641	radical SAM
EIO66_RS22200	COG0805	protein transport
EIO66_RS22215	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EIO66_RS22245	COG1739	Uncharacterized protein family UPF0029
EIO66_RS22285	COG1763	Mo-molybdopterin cofactor biosynthetic process
EIO66_RS22290	COG0746	molybdenum cofactor guanylyltransferase activity
EIO66_RS22295	COG3084	Protein conserved in bacteria
EIO66_RS22310	COG0204	Acyl-transferase
EIO66_RS22375	COG0561	phosphatase activity
EIO66_RS22420	COG1501	Belongs to the glycosyl hydrolase 31 family
EIO66_RS22425	COG2017	converts alpha-aldose to the beta-anomer
EIO66_RS22445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIO66_RS22450	COG1349	DNA-binding transcription factor activity
EIO66_RS22455	COG1011	Hydrolase
EIO66_RS22470	COG0456	acetyltransferase
EIO66_RS22480	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
EIO66_RS22495	COG2864	formate dehydrogenase
EIO66_RS22500	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS22515	COG3039	Transposase
EIO66_RS22525	COG3039	Transposase
EIO66_RS22540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EIO66_RS22550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EIO66_RS22555	COG2258	MOSC domain
EIO66_RS22570	COG2205	protein histidine kinase activity
EIO66_RS22575	COG0745	RESPONSE REGULATOR receiver
EIO66_RS22580	COG3678	ATP-independent chaperone mediated protein folding
EIO66_RS22600	COG2134	cdp-diacylglycerol pyrophosphatase
EIO66_RS22605	COG2211	Major facilitator Superfamily
EIO66_RS22620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EIO66_RS22640	COG3152	Membrane
EIO66_RS22650	COG1494	fructose-1,6-bisphosphatase
EIO66_RS22660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EIO66_RS22675	COG1575	Belongs to the MenA family. Type 1 subfamily
EIO66_RS22690	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EIO66_RS22695	COG1609	Transcriptional regulator
EIO66_RS22700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EIO66_RS22730	COG0626	cystathionine gamma-synthase activity
EIO66_RS22735	COG0460	homoserine dehydrogenase
EIO66_RS22735	COG0527	aspartate kinase activity
EIO66_RS22740	COG0668	transmembrane transport
EIO66_RS22755	COG0737	Belongs to the 5'-nucleotidase family
EIO66_RS22770	COG3738	Protein conserved in bacteria
EIO66_RS22775	COG0371	Dehydrogenase
EIO66_RS22785	COG2207	Transcriptional regulator
EIO66_RS22825	COG0583	DNA-binding transcription factor activity
EIO66_RS22935	COG0250	Participates in transcription elongation, termination and antitermination
EIO66_RS23000	COG2104	thiamine diphosphate biosynthetic process
EIO66_RS23005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EIO66_RS23070	COG0151	Belongs to the GarS family
EIO66_RS23110	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EIO66_RS23155	COG3122	Protein conserved in bacteria
EIO66_RS23160	COG1187	pseudouridine synthase activity
EIO66_RS23195	COG5301	cellulose 1,4-beta-cellobiosidase activity
EIO66_RS23225	COG2246	polysaccharide biosynthetic process
EIO66_RS23310	COG0527	aspartate kinase activity
EIO66_RS23335	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EIO66_RS23345	COG3833	ABC-type maltose transport systems, permease component
EIO66_RS23390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EIO66_RS23400	COG0534	Mate efflux family protein
EIO66_RS23415	COG0735	belongs to the Fur family
EIO66_RS23465	COG2315	Protein conserved in bacteria
EIO66_RS23525	COG3039	Transposase
EIO66_RS23545	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EIO66_RS23565	COG2252	PERMEase
EIO66_RS23575	COG0025	NhaP-type Na H and K H
EIO66_RS23580	COG0583	DNA-binding transcription factor activity
EIO66_RS23585	COG1380	Effector of murein hydrolase LrgA
EIO66_RS23590	COG1346	cytolysis
EIO66_RS23600	COG3162	membrane
EIO66_RS23605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EIO66_RS23615	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EIO66_RS23620	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS23625	COG3301	Polysulphide reductase, NrfD
EIO66_RS23630	COG1138	Cytochrome C-type biogenesis protein
EIO66_RS23635	COG4235	cytochrome complex assembly
EIO66_RS23640	COG1301	dicarboxylic acid transport
EIO66_RS23645	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EIO66_RS23665	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EIO66_RS23670	COG2824	Alkylphosphonate utilization operon protein PhnA
EIO66_RS23700	COG0531	amino acid
EIO66_RS23705	COG2207	Transcriptional regulator
EIO66_RS23710	COG1982	Orn Lys Arg decarboxylase major
EIO66_RS23715	COG2169	Transcriptional regulator
EIO66_RS23730	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EIO66_RS23730	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EIO66_RS23735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EIO66_RS23745	COG4565	transcriptional regulatory protein
EIO66_RS23750	COG3290	protein histidine kinase activity
EIO66_RS23760	COG0437	4 iron, 4 sulfur cluster binding
EIO66_RS23765	COG3302	dmso reductase anchor subunit
EIO66_RS23770	COG3381	protein complex oligomerization
EIO66_RS23790	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EIO66_RS23795	COG2197	response regulator
EIO66_RS23900	COG0671	phosphoesterase, PA-phosphatase related
EIO66_RS23910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIO66_RS23910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS23915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIO66_RS23925	COG3716	PTS system mannose fructose sorbose family IID component
EIO66_RS23930	COG1063	alcohol dehydrogenase
EIO66_RS23935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EIO66_RS23940	COG1063	alcohol dehydrogenase
EIO66_RS23945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EIO66_RS23950	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EIO66_RS23950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EIO66_RS24010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EIO66_RS24020	COG0629	single-stranded DNA binding
EIO66_RS24165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EIO66_RS24175	COG4974	Belongs to the 'phage' integrase family
EIO66_RS24195	COG0789	Transcriptional regulator
EIO66_RS24205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EIO66_RS24210	COG1393	Belongs to the ArsC family
EIO66_RS24215	COG0431	NADPH-dependent FMN reductase
EIO66_RS24250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIO66_RS24260	COG3039	Transposase
EIO66_RS24315	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIO66_RS24345	COG0739	heme binding
EIO66_RS24355	COG2132	Multicopper oxidase
EIO66_RS24360	COG3667	copper resistance
EIO66_RS24365	COG2372	response to copper ion
EIO66_RS24370	COG1276	copper resistance
EIO66_RS24375	COG0745	RESPONSE REGULATOR receiver
EIO66_RS24380	COG2205	protein histidine kinase activity
EIO66_RS24395	COG3039	Transposase
EIO66_RS24410	COG1309	transcriptional regulator
EIO66_RS24425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EIO66_RS24430	COG1027	Aspartate ammonia-lyase
EIO66_RS24435	COG3030	protein affecting phage T7 exclusion by the F plasmid
EIO66_RS24440	COG0531	amino acid
EIO66_RS24485	COG5510	response to toxic substance
EIO66_RS24515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EIO66_RS24520	COG1053	succinate dehydrogenase
EIO66_RS24540	COG3264	Mechanosensitive ion channel
EIO66_RS24540	COG1511	domain protein
EIO66_RS24560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIO66_RS24585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EIO66_RS24585	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EIO66_RS24590	COG0802	atpase or kinase
EIO66_RS24615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EIO66_RS24620	COG0330	HflC and HflK could
EIO66_RS24625	COG0330	HflC and HflK could
EIO66_RS24630	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EIO66_RS24650	COG0557	exoribonuclease II activity
EIO66_RS24660	COG3789	protein conserved in bacteria
EIO66_RS24665	COG1842	Phage shock protein A
EIO66_RS24675	COG3766	membrane
EIO66_RS24680	COG5463	Belongs to the UPF0441 family
EIO66_RS24685	COG0754	glutathionylspermidine amidase activity
EIO66_RS24690	COG1960	acyl-CoA dehydrogenase activity
EIO66_RS24700	COG3650	response to hydrogen peroxide
EIO66_RS24705	COG1073	alpha beta
EIO66_RS24775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EIO66_RS24790	COG3061	Opacity-associated protein A
EIO66_RS24795	COG0545	Peptidyl-prolyl cis-trans isomerase
EIO66_RS24800	COG1113	amino acid transport
EIO66_RS24820	COG0697	spore germination
EIO66_RS24825	COG0702	epimerase
EIO66_RS24830	COG1733	regulation of RNA biosynthetic process
EIO66_RS24850	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EIO66_RS24865	COG1253	flavin adenine dinucleotide binding
EIO66_RS24885	COG2105	PFAM AIG2 family protein
EIO66_RS24890	COG2271	Major facilitator Superfamily
EIO66_RS24895	COG3964	amidohydrolase
EIO66_RS24910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EIO66_RS24920	COG0312	modulator of DNA gyrase
EIO66_RS24955	COG3964	amidohydrolase
EIO66_RS24970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIO66_RS24970	COG3711	transcriptional antiterminator
EIO66_RS24975	COG3077	Addiction module antitoxin, RelB DinJ family
EIO66_RS24980	COG2026	Addiction module toxin, RelE StbE family
EIO66_RS24995	COG0366	Alpha amylase catalytic
EIO66_RS25000	COG1263	PTS System
EIO66_RS25000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIO66_RS25050	COG1438	arginine binding
EIO66_RS25055	COG1288	antiporter activity
EIO66_RS25080	COG2731	YhcH YjgK YiaL family protein
EIO66_RS25120	COG2927	DNA polymerase III (CHI subunit)
EIO66_RS25135	COG0795	lipopolysaccharide-transporting ATPase activity
EIO66_RS25140	COG0795	lipopolysaccharide-transporting ATPase activity
EIO66_RS25145	COG1609	Transcriptional regulator
EIO66_RS25150	COG2610	gluconate transmembrane transporter activity
EIO66_RS25165	COG3265	gluconokinase activity
EIO66_RS25170	COG1064	alcohol dehydrogenase
EIO66_RS25180	COG0582	viral genome integration into host DNA
EIO66_RS25275	COG3547	Transposase (IS116 IS110 IS902 family)
EIO66_RS25290	COG1196	nuclear chromosome segregation
EIO66_RS25295	COG3039	Transposase
EIO66_RS25325	COG3039	Transposase
EIO66_RS25335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EIO66_RS25370	COG0412	Dienelactone hydrolase
EIO66_RS25375	COG2186	Transcriptional regulator
EIO66_RS25395	COG0583	DNA-binding transcription factor activity
EIO66_RS25400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EIO66_RS25405	COG0700	Nucleoside recognition
EIO66_RS25410	COG3366	ferrous iron transmembrane transporter activity
EIO66_RS25415	COG0477	Major facilitator Superfamily
EIO66_RS25420	COG2733	membrane
EIO66_RS25430	COG5464	transposase or invertase
EIO66_RS25435	COG1012	belongs to the aldehyde dehydrogenase family
EIO66_RS25475	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EIO66_RS25480	COG1715	Restriction endonuclease
EIO66_RS25495	COG0523	cobalamin synthesis protein
EIO66_RS25500	COG2879	small protein
EIO66_RS25505	COG1966	Carbon starvation protein
EIO66_RS25510	COG0840	transmembrane signaling receptor activity
EIO66_RS25530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIO66_RS25535	COG3715	PTS system
EIO66_RS25540	COG3716	PTS system mannose fructose sorbose family IID component
EIO66_RS25545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EIO66_RS25565	COG1484	DNA-dependent DNA replication
EIO66_RS25580	COG2966	Psort location CytoplasmicMembrane, score
EIO66_RS25585	COG2197	response regulator
EIO66_RS25590	COG2197	response regulator
EIO66_RS25595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EIO66_RS25600	COG4114	ferric iron reductase
EIO66_RS25605	COG3706	GGDEF domain
EIO66_RS25635	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EIO66_RS25645	COG1011	Hydrolase
EIO66_RS25655	COG2823	Periplasmic or secreted lipoprotein
EIO66_RS25665	COG4667	esterase of the alpha-beta hydrolase superfamily
EIO66_RS25670	COG0084	hydrolase, TatD family'
EIO66_RS25675	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EIO66_RS25680	COG1328	CTP reductase activity
EIO66_RS25715	COG3039	Transposase
EIO66_RS25730	COG3539	Fimbrial protein
EIO66_RS25750	COG0560	Phosphoserine phosphatase
EIO66_RS25765	COG0488	(ABC) transporter
EIO66_RS25795	COG2207	Transcriptional regulator
EIO66_RS25795	COG3708	Transcriptional regulator
EIO66_RS25800	COG3045	CreA protein
EIO66_RS25805	COG0745	RESPONSE REGULATOR receiver
EIO66_RS25810	COG2205	protein histidine kinase activity
EIO66_RS25815	COG4452	Inner membrane protein CreD
EIO66_RS25835	COG3121	Chaperone
EIO66_RS25855	COG0745	RESPONSE REGULATOR receiver
EIO66_RS25865	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EIO66_RS25970	COG2944	sequence-specific DNA binding
EIO66_RS26010	COG1192	Involved in chromosome partitioning
EIO66_RS26210	COG3726	membrane protein affecting hemolysin expression
