locus-tag	class	description
A1D48_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A1D48_RS00035	COG0561	phosphatase activity
A1D48_RS00055	COG2205	protein histidine kinase activity
A1D48_RS00055	COG2198	Histidine kinase
A1D48_RS00055	COG0784	Response regulator, receiver
A1D48_RS00060	COG1879	ABC-type sugar transport system periplasmic component
A1D48_RS00065	COG0745	RESPONSE REGULATOR receiver
A1D48_RS00070	COG3005	denitrification pathway
A1D48_RS00085	COG1858	cytochrome C peroxidase
A1D48_RS00095	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1D48_RS00100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1D48_RS00105	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1D48_RS00115	COG1138	Cytochrome C-type biogenesis protein
A1D48_RS00120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D48_RS00125	COG3088	subunit of a heme lyase
A1D48_RS00125	COG4235	cytochrome complex assembly
A1D48_RS00130	COG0823	Involved in the tonB-independent uptake of proteins
A1D48_RS00135	COG5645	(Lipo)protein
A1D48_RS00155	COG2149	membrane
A1D48_RS00165	COG0641	radical SAM
A1D48_RS00175	COG2610	gluconate transmembrane transporter activity
A1D48_RS00180	COG0583	DNA-binding transcription factor activity
A1D48_RS00190	COG2814	Major facilitator Superfamily
A1D48_RS00215	COG0028	Belongs to the TPP enzyme family
A1D48_RS00220	COG0440	acetolactate synthase activity
A1D48_RS00225	COG1349	DNA-binding transcription factor activity
A1D48_RS00235	COG0738	Major facilitator superfamily
A1D48_RS00270	COG2188	Transcriptional regulator
A1D48_RS00275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS00275	COG3711	transcriptional antiterminator
A1D48_RS00280	COG3414	Phosphotransferase system galactitol-specific IIB component
A1D48_RS00285	COG3775	system Galactitol-specific IIC component
A1D48_RS00330	COG2723	6-phospho-beta-galactosidase activity
A1D48_RS00350	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS00350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D48_RS00355	COG3715	PTS system
A1D48_RS00360	COG3716	PTS system mannose fructose sorbose family IID component
A1D48_RS00375	COG5464	transposase or invertase
A1D48_RS00385	COG1285	pathogenesis
A1D48_RS00410	COG1335	isochorismatase
A1D48_RS00420	COG3710	Transcriptional regulator
A1D48_RS00435	COG2771	luxR family
A1D48_RS00470	COG2211	Major facilitator Superfamily
A1D48_RS00475	COG1501	Belongs to the glycosyl hydrolase 31 family
A1D48_RS00480	COG2982	Protein involved in outer membrane biogenesis
A1D48_RS00485	COG2233	PERMEase
A1D48_RS00490	COG0786	glutamate:sodium symporter activity
A1D48_RS00495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A1D48_RS00500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1D48_RS00505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A1D48_RS00525	COG2860	membrane
A1D48_RS00535	COG0583	DNA-binding transcription factor activity
A1D48_RS00540	COG1561	YicC-like family, N-terminal region
A1D48_RS00570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A1D48_RS00600	COG1519	Transferase
A1D48_RS00605	COG0859	PFAM glycosyl transferase family 9
A1D48_RS00610	COG0438	transferase activity, transferring glycosyl groups
A1D48_RS00685	COG1216	Glycosyl transferase, family 2
A1D48_RS00690	COG2861	carbohydrate metabolic process
A1D48_RS00695	COG4942	peptidase
A1D48_RS00705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A1D48_RS00710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A1D48_RS00730	COG2271	Major facilitator Superfamily
A1D48_RS00745	COG1609	Transcriptional regulator
A1D48_RS00750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A1D48_RS00760	COG2186	Transcriptional regulator
A1D48_RS00790	COG3722	fumarate hydratase activity
A1D48_RS00800	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS00800	COG2213	PTS system mannitol-specific
A1D48_RS00805	COG0625	glutathione transferase activity
A1D48_RS00815	COG3276	selenocysteine insertion sequence binding
A1D48_RS00820	COG1940	carbohydrate kinase activity
A1D48_RS00825	COG1012	belongs to the aldehyde dehydrogenase family
A1D48_RS00835	COG0235	Class ii aldolase
A1D48_RS00840	COG3623	hexulose-6-phosphate isomerase
A1D48_RS00845	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A1D48_RS00850	COG1070	Carbohydrate kinase
A1D48_RS00855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A1D48_RS00860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A1D48_RS00865	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A1D48_RS00875	COG2731	YhcH YjgK YiaL family protein
A1D48_RS00885	COG1414	Transcriptional regulator
A1D48_RS00890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1D48_RS00895	COG3977	Valine--pyruvate aminotransferase
A1D48_RS00900	COG0366	Alpha amylase catalytic
A1D48_RS00905	COG2992	FlgJ-related protein
A1D48_RS00910	COG2207	Transcriptional regulator
A1D48_RS00910	COG1609	Transcriptional regulator
A1D48_RS00925	COG1070	Carbohydrate kinase
A1D48_RS00930	COG4682	membrane
A1D48_RS00935	COG3274	enterobacterial common antigen metabolic process
A1D48_RS00960	COG2801	Transposase and inactivated derivatives
A1D48_RS00995	COG1278	Cold shock
A1D48_RS01000	COG2944	sequence-specific DNA binding
A1D48_RS01015	COG2885	chlorophyll binding
A1D48_RS01020	COG0243	molybdopterin cofactor binding
A1D48_RS01025	COG0456	acetyltransferase
A1D48_RS01030	COG2818	Glycosylase
A1D48_RS01035	COG5571	outer membrane autotransporter
A1D48_RS01095	COG0747	negative chemotaxis
A1D48_RS01100	COG0601	transmembrane transport
A1D48_RS01105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1D48_RS01110	COG0444	Belongs to the ABC transporter superfamily
A1D48_RS01115	COG4608	Belongs to the ABC transporter superfamily
A1D48_RS01120	COG0814	amino acid
A1D48_RS01185	COG2200	EAL domain
A1D48_RS01185	COG2199	diguanylate cyclase activity
A1D48_RS01200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D48_RS01205	COG2200	EAL domain
A1D48_RS01210	COG2982	Protein involved in outer membrane biogenesis
A1D48_RS01215	COG0477	Major facilitator Superfamily
A1D48_RS01220	COG1295	ribonuclease BN
A1D48_RS01225	COG0583	DNA-binding transcription factor activity
A1D48_RS01230	COG2197	response regulator
A1D48_RS01250	COG2188	Transcriptional regulator
A1D48_RS01255	COG2222	sugar isomerase
A1D48_RS01260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D48_RS01265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A1D48_RS01275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D48_RS01285	COG1082	Xylose isomerase domain protein TIM barrel
A1D48_RS01290	COG2814	Major facilitator Superfamily
A1D48_RS01295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1D48_RS01300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A1D48_RS01340	COG0306	phosphate transporter
A1D48_RS01345	COG2081	HI0933 family
A1D48_RS01410	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1D48_RS01440	COG0739	heme binding
A1D48_RS01450	COG2132	Multicopper oxidase
A1D48_RS01455	COG3667	copper resistance
A1D48_RS01460	COG2372	response to copper ion
A1D48_RS01465	COG1276	copper resistance
A1D48_RS01470	COG0745	RESPONSE REGULATOR receiver
A1D48_RS01475	COG2205	protein histidine kinase activity
A1D48_RS01485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1D48_RS01490	COG0842	Transport permease protein
A1D48_RS01490	COG1129	ABC transporter
A1D48_RS01495	COG0842	Transport permease protein
A1D48_RS01510	COG0628	permease
A1D48_RS01525	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A1D48_RS01545	COG3714	YhhN family
A1D48_RS01555	COG3776	membrane
A1D48_RS01560	COG0742	ribosomal rna small subunit methyltransferase
A1D48_RS01565	COG0552	protein localization to endoplasmic reticulum
A1D48_RS01570	COG2884	Cell division ATP-binding protein ftsE
A1D48_RS01575	COG2177	Part of the ABC transporter FtsEX involved in
A1D48_RS01650	COG0584	glycerophosphoryl diester phosphodiesterase
A1D48_RS01660	COG0405	Gamma-glutamyltransferase
A1D48_RS01665	COG1735	metal-dependent hydrolase with the TIM-barrel fold
A1D48_RS01680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D48_RS01685	COG1247	-acetyltransferase
A1D48_RS01695	COG0673	inositol 2-dehydrogenase activity
A1D48_RS01700	COG1741	Belongs to the pirin family
A1D48_RS01705	COG1609	Transcriptional regulator
A1D48_RS01710	COG3265	gluconokinase activity
A1D48_RS01715	COG2610	gluconate transmembrane transporter activity
A1D48_RS01730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A1D48_RS01750	COG0058	SHG alpha-glucan phosphorylase activity
A1D48_RS01755	COG1414	Transcriptional regulator
A1D48_RS01760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A1D48_RS01765	COG0129	dihydroxy-acid dehydratase activity
A1D48_RS01775	COG0371	Dehydrogenase
A1D48_RS01790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A1D48_RS01805	COG1349	DNA-binding transcription factor activity
A1D48_RS01810	COG4650	regulator
A1D48_RS01820	COG1690	Belongs to the RtcB family
A1D48_RS01840	COG0058	SHG alpha-glucan phosphorylase activity
A1D48_RS01845	COG1640	4-alpha-glucanotransferase
A1D48_RS01850	COG2610	gluconate transmembrane transporter activity
A1D48_RS01870	COG5464	transposase or invertase
A1D48_RS01885	COG1918	ferrous iron import across plasma membrane
A1D48_RS01895	COG2183	response to ionizing radiation
A1D48_RS01900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A1D48_RS01920	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A1D48_RS01930	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A1D48_RS01935	COG1011	Hydrolase
A1D48_RS01945	COG0494	nUDIX hydrolase
A1D48_RS01950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A1D48_RS01955	COG4972	Pilus assembly protein
A1D48_RS01960	COG3166	PFAM Fimbrial assembly family protein
A1D48_RS01975	COG4796	Type ii and iii secretion system protein
A1D48_RS01995	COG3266	domain, Protein
A1D48_RS02000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A1D48_RS02005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A1D48_RS02045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A1D48_RS02080	COG1289	transmembrane transporter activity
A1D48_RS02090	COG1765	OsmC-like protein
A1D48_RS02095	COG3954	Phosphoribulokinase
A1D48_RS02105	COG0429	hydrolase of the alpha beta-hydrolase fold
A1D48_RS02125	COG0488	(ABC) transporter
A1D48_RS02140	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A1D48_RS02145	COG1047	Peptidyl-prolyl cis-trans
A1D48_RS02160	COG0545	Peptidyl-prolyl cis-trans isomerase
A1D48_RS02165	COG2964	Protein conserved in bacteria
A1D48_RS02235	COG0051	transcription antitermination factor activity, RNA binding
A1D48_RS02260	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A1D48_RS02340	COG0201	protein transport
A1D48_RS02380	COG0789	Transcriptional regulator
A1D48_RS02385	COG3036	rescue of stalled ribosome
A1D48_RS02415	COG0758	DNA mediated transformation
A1D48_RS02425	COG0551	DNA topoisomerase type I activity
A1D48_RS02445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A1D48_RS02490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1D48_RS02495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1D48_RS02500	COG1309	transcriptional regulator
A1D48_RS02515	COG2189	Belongs to the N(4) N(6)-methyltransferase family
A1D48_RS02540	COG4145	pantothenate transmembrane transporter activity
A1D48_RS02545	COG3924	membrane
A1D48_RS02550	COG0439	Biotin carboxylase
A1D48_RS02555	COG0511	ligase activity, forming carbon-carbon bonds
A1D48_RS02570	COG0604	alcohol dehydrogenase
A1D48_RS02575	COG2200	EAL domain
A1D48_RS02575	COG2199	diguanylate cyclase activity
A1D48_RS02590	COG1077	Cell shape determining protein MreB Mrl
A1D48_RS02595	COG1792	Involved in formation and maintenance of cell shape
A1D48_RS02600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A1D48_RS02615	COG3164	Protein of unknown function
A1D48_RS02620	COG0312	modulator of DNA gyrase
A1D48_RS02625	COG0583	DNA-binding transcription factor activity
A1D48_RS02645	COG2732	(Barnase) inhibitor
A1D48_RS02670	COG2188	Transcriptional regulator
A1D48_RS02680	COG0471	metal ion transport
A1D48_RS02685	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A1D48_RS02690	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A1D48_RS02695	COG3630	sodium ion export across plasma membrane
A1D48_RS02705	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A1D48_RS02720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1D48_RS02725	COG3105	Protein conserved in bacteria
A1D48_RS02730	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A1D48_RS02750	COG0625	glutathione transferase activity
A1D48_RS02755	COG2969	positive regulation of protein catabolic process
A1D48_RS02785	COG2731	YhcH YjgK YiaL family protein
A1D48_RS02790	COG0402	S-adenosylhomocysteine deaminase activity
A1D48_RS02795	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A1D48_RS02800	COG4804	nuclease activity
A1D48_RS02805	COG0493	'glutamate synthase
A1D48_RS02810	COG0067	glutamate synthase
A1D48_RS02810	COG0070	glutamate synthase
A1D48_RS02810	COG0069	glutamate synthase activity
A1D48_RS02825	COG1242	4 iron, 4 sulfur cluster binding
A1D48_RS02830	COG0784	Response regulator, receiver
A1D48_RS02830	COG2198	Histidine kinase
A1D48_RS02830	COG5002	protein histidine kinase activity
A1D48_RS02835	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A1D48_RS02845	COG0515	serine threonine protein kinase
A1D48_RS02855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS02880	COG1137	ATPase activity
A1D48_RS02885	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A1D48_RS02890	COG3117	lipopolysaccharide transmembrane transporter activity
A1D48_RS02895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A1D48_RS02905	COG0530	calcium, potassium:sodium antiporter activity
A1D48_RS02910	COG1127	ABC transporter
A1D48_RS02915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A1D48_RS02920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A1D48_RS02925	COG2854	intermembrane phospholipid transfer
A1D48_RS02930	COG3113	response to antibiotic
A1D48_RS02935	COG5007	Belongs to the BolA IbaG family
A1D48_RS02945	COG3423	Transcriptional regulator
A1D48_RS02950	COG0142	geranyltranstransferase activity
A1D48_RS02965	COG0697	spore germination
A1D48_RS02975	COG2027	D-alanyl-D-alanine carboxypeptidase
A1D48_RS02985	COG1534	Rna-binding protein
A1D48_RS03005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A1D48_RS03015	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A1D48_RS03080	COG0513	Belongs to the DEAD box helicase family
A1D48_RS03085	COG0814	amino acid
A1D48_RS03090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A1D48_RS03095	COG0826	peptidase U32
A1D48_RS03100	COG0826	peptidase U32
A1D48_RS03105	COG3154	lipid carrier protein
A1D48_RS03110	COG3153	acetyltransferase
A1D48_RS03125	COG0693	protein deglycase activity
A1D48_RS03130	COG0702	epimerase
A1D48_RS03135	COG2823	Periplasmic or secreted lipoprotein
A1D48_RS03150	COG3107	peptidoglycan biosynthetic process
A1D48_RS03155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A1D48_RS03165	COG1063	alcohol dehydrogenase
A1D48_RS03170	COG3775	system Galactitol-specific IIC component
A1D48_RS03175	COG3414	Phosphotransferase system galactitol-specific IIB component
A1D48_RS03180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS03195	COG2721	sulfolactate sulfo-lyase activity
A1D48_RS03205	COG2084	Dehydrogenase
A1D48_RS03210	COG1929	Belongs to the glycerate kinase type-1 family
A1D48_RS03240	COG0583	DNA-binding transcription factor activity
A1D48_RS03260	COG1882	Formate acetyltransferase
A1D48_RS03265	COG1760	l-serine dehydratase
A1D48_RS03270	COG0814	amino acid
A1D48_RS03285	COG1741	Belongs to the pirin family
A1D48_RS03290	COG0583	DNA-binding transcription factor activity
A1D48_RS03295	COG3152	Membrane
A1D48_RS03300	COG0435	Glutathione S-transferase
A1D48_RS03305	COG2259	Doxx family
A1D48_RS03315	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
A1D48_RS03320	COG4575	ribosome binding
A1D48_RS03325	COG1422	Protein of unknown function (DUF1090)
A1D48_RS03335	COG0586	Pfam SNARE associated Golgi protein
A1D48_RS03355	COG0673	inositol 2-dehydrogenase activity
A1D48_RS03360	COG2949	membrane
A1D48_RS03365	COG1451	nucleotide metabolic process
A1D48_RS03375	COG0446	pyridine nucleotide-disulphide oxidoreductase
A1D48_RS03375	COG1902	pentaerythritol trinitrate reductase activity
A1D48_RS03390	COG0840	transmembrane signaling receptor activity
A1D48_RS03400	COG1695	Transcriptional regulator
A1D48_RS03405	COG2375	cellular response to nickel ion
A1D48_RS03510	COG1802	Transcriptional regulator
A1D48_RS03510	COG4626	Terminase
A1D48_RS03545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A1D48_RS03565	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A1D48_RS03580	COG4991	sh3 domain protein
A1D48_RS03590	COG3025	triphosphatase activity
A1D48_RS03610	COG2268	Band 7 protein
A1D48_RS03615	COG1585	Membrane protein implicated in regulation of membrane protease activity
A1D48_RS03665	COG0754	glutathionylspermidine amidase activity
A1D48_RS03685	COG0494	nUDIX hydrolase
A1D48_RS03690	COG3151	Protein conserved in bacteria
A1D48_RS03695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A1D48_RS03700	COG3150	esterase
A1D48_RS03710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A1D48_RS03715	COG2249	NAD(P)H dehydrogenase (quinone) activity
A1D48_RS03720	COG0642	Histidine kinase
A1D48_RS03730	COG3111	PFAM Bacterial OB fold (BOF) protein
A1D48_RS03735	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A1D48_RS03785	COG0471	metal ion transport
A1D48_RS03795	COG1979	alcohol dehydrogenase
A1D48_RS03800	COG2207	Transcriptional regulator
A1D48_RS03825	COG0848	biopolymer transport protein
A1D48_RS03830	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS03860	COG0840	transmembrane signaling receptor activity
A1D48_RS03875	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A1D48_RS03880	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS03885	COG5557	Pfam Polysulphide reductase, NrfD
A1D48_RS03890	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A1D48_RS03895	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A1D48_RS03900	COG1773	rubredoxin
A1D48_RS03910	COG0298	carbon dioxide binding
A1D48_RS03915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1D48_RS03925	COG0625	glutathione transferase activity
A1D48_RS03930	COG0754	glutathionylspermidine amidase activity
A1D48_RS03945	COG0246	Mannitol dehydrogenase
A1D48_RS03955	COG2271	Major facilitator Superfamily
A1D48_RS03980	COG1012	belongs to the aldehyde dehydrogenase family
A1D48_RS03985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A1D48_RS03995	COG0531	amino acid
A1D48_RS04090	COG1811	Na channel or pump
A1D48_RS04100	COG1982	Orn Lys Arg decarboxylase major
A1D48_RS04105	COG2211	Major facilitator Superfamily
A1D48_RS04135	COG3171	Protein conserved in bacteria
A1D48_RS04145	COG0252	asparaginase activity
A1D48_RS04155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A1D48_RS04170	COG0762	integral membrane protein
A1D48_RS04175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A1D48_RS04180	COG2805	Type II/IV secretion system protein
A1D48_RS04205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A1D48_RS04210	COG2356	endonuclease I
A1D48_RS04220	COG2814	Major facilitator Superfamily
A1D48_RS04245	COG1166	arginine decarboxylase activity
A1D48_RS04255	COG2186	Transcriptional regulator
A1D48_RS04265	COG4948	Mandelate Racemase Muconate Lactonizing
A1D48_RS04275	COG0246	Mannitol dehydrogenase
A1D48_RS04280	COG1063	alcohol dehydrogenase
A1D48_RS04285	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A1D48_RS04290	COG2731	YhcH YjgK YiaL family protein
A1D48_RS04295	COG2267	carboxylic ester hydrolase activity
A1D48_RS04310	COG0501	Belongs to the peptidase M48B family
A1D48_RS04315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A1D48_RS04320	COG1122	ATPase activity
A1D48_RS04325	COG1122	ATPase activity
A1D48_RS04360	COG0191	fructose-bisphosphate aldolase activity
A1D48_RS04365	COG0668	transmembrane transport
A1D48_RS04375	COG2968	Membrane
A1D48_RS04395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A1D48_RS04400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A1D48_RS04425	COG0006	proline dipeptidase activity
A1D48_RS04430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1D48_RS04435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1D48_RS04465	COG2723	6-phospho-beta-galactosidase activity
A1D48_RS04475	COG1272	protein, Hemolysin III
A1D48_RS04545	COG4942	peptidase
A1D48_RS04590	COG3188	usher protein
A1D48_RS04625	COG0814	amino acid
A1D48_RS04640	COG0183	Belongs to the thiolase family
A1D48_RS04655	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS04660	COG2814	Major facilitator Superfamily
A1D48_RS04665	COG1794	racemase activity, acting on amino acids and derivatives
A1D48_RS04670	COG0583	DNA-binding transcription factor activity
A1D48_RS04680	COG1609	Transcriptional regulator
A1D48_RS04710	COG0667	Aldo Keto reductase
A1D48_RS04720	COG0861	Integral membrane protein TerC family
A1D48_RS04755	COG2165	general secretion pathway protein
A1D48_RS04760	COG4795	General secretion pathway protein
A1D48_RS04770	COG4967	type IV pilus modification protein PilV
A1D48_RS04775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A1D48_RS04780	COG1025	Belongs to the peptidase M16 family
A1D48_RS04785	COG1074	ATP-dependent DNA helicase activity
A1D48_RS04790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A1D48_RS04800	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1D48_RS04815	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A1D48_RS04820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A1D48_RS04825	COG2962	Rard protein
A1D48_RS04830	COG2166	iron-sulfur cluster assembly
A1D48_RS04835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A1D48_RS04845	COG0583	DNA-binding transcription factor activity
A1D48_RS04850	COG2363	Small membrane protein
A1D48_RS04860	COG1349	DNA-binding transcription factor activity
A1D48_RS04880	COG0738	Major facilitator superfamily
A1D48_RS04885	COG0235	Class ii aldolase
A1D48_RS04890	COG1454	alcohol dehydrogenase
A1D48_RS04905	COG1760	l-serine dehydratase
A1D48_RS04910	COG0814	amino acid
A1D48_RS04915	COG1611	Belongs to the LOG family
A1D48_RS04935	COG3098	single-species biofilm formation
A1D48_RS04945	COG0716	FMN binding
A1D48_RS04955	COG2271	Major facilitator Superfamily
A1D48_RS04960	COG4948	Mandelate Racemase Muconate Lactonizing
A1D48_RS04965	COG4948	Mandelate Racemase Muconate Lactonizing
A1D48_RS04970	COG1929	Belongs to the glycerate kinase type-1 family
A1D48_RS04975	COG3437	response regulator, receiver
A1D48_RS04975	COG2205	protein histidine kinase activity
A1D48_RS04975	COG4999	Histidine kinase
A1D48_RS04975	COG3850	Histidine kinase
A1D48_RS04985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A1D48_RS05020	COG3539	Fimbrial protein
A1D48_RS05025	COG3121	Chaperone
A1D48_RS05030	COG3188	usher protein
A1D48_RS05035	COG3539	Fimbrial protein
A1D48_RS05040	COG3956	TIGRFAM MazG family protein
A1D48_RS05055	COG0602	queuosine metabolic process
A1D48_RS05060	COG0321	lipoyl(octanoyl) transferase activity
A1D48_RS05060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A1D48_RS05065	COG0720	synthase
A1D48_RS05075	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A1D48_RS05100	COG1203	CRISPR-associated helicase, Cas3
A1D48_RS05115	COG1857	crispr-associated protein
A1D48_RS05130	COG1518	maintenance of DNA repeat elements
A1D48_RS05135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A1D48_RS05140	COG2234	aminopeptidase activity
A1D48_RS05210	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A1D48_RS05215	COG0163	prenyltransferase activity
A1D48_RS05225	COG1349	DNA-binding transcription factor activity
A1D48_RS05230	COG2084	Dehydrogenase
A1D48_RS05240	COG0235	Class ii aldolase
A1D48_RS05245	COG3622	Belongs to the hyi family
A1D48_RS05250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D48_RS05255	COG2610	gluconate transmembrane transporter activity
A1D48_RS05265	COG0477	Major facilitator Superfamily
A1D48_RS05340	COG2207	Transcriptional regulator
A1D48_RS05430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1D48_RS05515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1D48_RS05520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1D48_RS05525	COG1121	(ABC) transporter
A1D48_RS05545	COG0309	Hydrogenase expression formation protein (HypE)
A1D48_RS05550	COG0409	Hydrogenase expression formation protein
A1D48_RS05555	COG0298	carbon dioxide binding
A1D48_RS05560	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A1D48_RS05580	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1D48_RS05585	COG0651	ATP synthesis coupled electron transport
A1D48_RS05590	COG0650	Formate hydrogenlyase subunit 4
A1D48_RS05595	COG3261	NADH dehydrogenase
A1D48_RS05595	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A1D48_RS05600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A1D48_RS05605	COG3260	NADH ubiquinone oxidoreductase 20
A1D48_RS05615	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A1D48_RS05625	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1D48_RS05630	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A1D48_RS05650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A1D48_RS05650	COG0517	IMP dehydrogenase activity
A1D48_RS05655	COG1349	DNA-binding transcription factor activity
A1D48_RS05660	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS05675	COG3732	PTS system glucitol sorbitol-specific
A1D48_RS05680	COG3730	PTS system glucitol sorbitol-specific
A1D48_RS05685	COG2951	lytic endotransglycosylase activity
A1D48_RS05695	COG1546	Belongs to the CinA family
A1D48_RS05720	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A1D48_RS05755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1D48_RS05760	COG1238	metal cluster binding
A1D48_RS05780	COG2814	Major facilitator Superfamily
A1D48_RS05785	COG1566	PFAM secretion protein HlyD family protein
A1D48_RS05790	COG1846	Transcriptional regulator
A1D48_RS05795	COG2814	Major facilitator Superfamily
A1D48_RS05845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1D48_RS05855	COG4575	ribosome binding
A1D48_RS05885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A1D48_RS05890	COG0640	Transcriptional regulator
A1D48_RS05895	COG0401	homolog of Blt101
A1D48_RS05905	COG1652	LysM domain
A1D48_RS05910	COG1802	Transcriptional regulator
A1D48_RS05915	COG1113	amino acid transport
A1D48_RS05920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A1D48_RS05925	COG1012	belongs to the aldehyde dehydrogenase family
A1D48_RS05930	COG0579	oxidoreductase
A1D48_RS05965	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A1D48_RS05980	COG2990	Protein conserved in bacteria
A1D48_RS06000	COG2819	hydrolase of the alpha beta superfamily
A1D48_RS06065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1D48_RS06090	COG2867	negative regulation of translational initiation
A1D48_RS06105	COG0497	DNA recombination
A1D48_RS06130	COG4536	flavin adenine dinucleotide binding
A1D48_RS06135	COG4137	Cytochrome C assembly protein
A1D48_RS06145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A1D48_RS06170	COG2199	diguanylate cyclase activity
A1D48_RS06185	COG0287	Prephenate dehydrogenase
A1D48_RS06185	COG1605	Chorismate mutase
A1D48_RS06195	COG1605	Chorismate mutase
A1D48_RS06195	COG0077	Prephenate dehydratase
A1D48_RS06205	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A1D48_RS06210	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1D48_RS06225	COG0542	response to heat
A1D48_RS06260	COG0477	Major facilitator Superfamily
A1D48_RS06265	COG5544	Lipoprotein
A1D48_RS06270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A1D48_RS06280	COG3148	PFAM DTW domain containing protein
A1D48_RS06285	COG3118	belongs to the thioredoxin family
A1D48_RS06290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1D48_RS06310	COG0583	DNA-binding transcription factor activity
A1D48_RS06315	COG0513	Belongs to the DEAD box helicase family
A1D48_RS06325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A1D48_RS06350	COG3086	response to oxidative stress
A1D48_RS06390	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A1D48_RS06400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1D48_RS06405	COG0583	DNA-binding transcription factor activity
A1D48_RS06410	COG2223	nitrite transmembrane transporter activity
A1D48_RS06415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A1D48_RS06420	COG1737	Transcriptional regulator
A1D48_RS06430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D48_RS06430	COG1263	PTS System
A1D48_RS06435	COG0560	Phosphoserine phosphatase
A1D48_RS06460	COG2205	protein histidine kinase activity
A1D48_RS06465	COG3170	Tfp pilus assembly protein FimV
A1D48_RS06470	COG2204	response regulator
A1D48_RS06475	COG0347	Belongs to the P(II) protein family
A1D48_RS06480	COG3104	oligopeptide transport
A1D48_RS06490	COG0531	amino acid
A1D48_RS06495	COG3710	Transcriptional regulator
A1D48_RS06500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1D48_RS06500	COG1017	nitric oxide dioxygenase activity
A1D48_RS06510	COG2814	Major facilitator Superfamily
A1D48_RS06515	COG3711	transcriptional antiterminator
A1D48_RS06525	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A1D48_RS06570	COG0822	iron-sulfur transferase activity
A1D48_RS06590	COG0633	Ferredoxin
A1D48_RS06595	COG2975	iron-sulfur cluster assembly
A1D48_RS06630	COG2897	thiosulfate sulfurtransferase activity
A1D48_RS06635	COG2373	Large extracellular alpha-helical protein
A1D48_RS06640	COG4953	penicillin-binding protein 1C
A1D48_RS06645	COG0243	molybdopterin cofactor binding
A1D48_RS06650	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS06695	COG2976	Protein conserved in bacteria
A1D48_RS06710	COG1645	bacterial-type flagellum-dependent swarming motility
A1D48_RS06745	COG0516	GMP reductase activity
A1D48_RS06745	COG0517	IMP dehydrogenase activity
A1D48_RS06765	COG3547	Transposase (IS116 IS110 IS902 family)
A1D48_RS06830	COG3133	Outer membrane lipoprotein
A1D48_RS06845	COG2200	EAL domain
A1D48_RS06860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A1D48_RS06875	COG2233	PERMEase
A1D48_RS06885	COG1393	Belongs to the ArsC family
A1D48_RS06895	COG0628	permease
A1D48_RS06900	COG3835	regulator
A1D48_RS06905	COG2610	gluconate transmembrane transporter activity
A1D48_RS06910	COG1929	Belongs to the glycerate kinase type-1 family
A1D48_RS06915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A1D48_RS06920	COG2716	regulation of RNA biosynthetic process
A1D48_RS06930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A1D48_RS06940	COG2321	neutral zinc metallopeptidase
A1D48_RS06960	COG1393	Belongs to the ArsC family
A1D48_RS06970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1D48_RS06975	COG3850	Histidine kinase
A1D48_RS06985	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1D48_RS06985	COG0493	'glutamate synthase
A1D48_RS07005	COG5342	invasion associated locus B
A1D48_RS07015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A1D48_RS07155	COG2837	iron assimilation
A1D48_RS07175	COG4208	sulfate ABC transporter
A1D48_RS07240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS07265	COG3530	Putative quorum-sensing-regulated virulence factor
A1D48_RS07270	COG0385	Bile acid
A1D48_RS07275	COG0583	DNA-binding transcription factor activity
A1D48_RS07285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A1D48_RS07290	COG2211	Major facilitator Superfamily
A1D48_RS07300	COG0583	DNA-binding transcription factor activity
A1D48_RS07330	COG3415	Transposase
A1D48_RS07335	COG3415	Transposase
A1D48_RS07355	COG2200	EAL domain
A1D48_RS07355	COG2199	diguanylate cyclase activity
A1D48_RS07360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A1D48_RS07375	COG0667	Aldo Keto reductase
A1D48_RS07385	COG3961	Belongs to the TPP enzyme family
A1D48_RS07400	COG0436	Aminotransferase
A1D48_RS07410	COG1560	Kdo2-lipid A biosynthetic process
A1D48_RS07460	COG2116	formate transmembrane transporter activity
A1D48_RS07475	COG3691	Protein conserved in bacteria
A1D48_RS07490	COG2062	phosphohistidine phosphatase, SixA
A1D48_RS07515	COG0730	response to heat
A1D48_RS07520	COG3101	peptidyl-lysine hydroxylation
A1D48_RS07535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1D48_RS07580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A1D48_RS07590	COG0586	Pfam SNARE associated Golgi protein
A1D48_RS07600	COG0285	dihydrofolate synthase activity
A1D48_RS07605	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A1D48_RS07610	COG1286	toxin biosynthetic process
A1D48_RS07615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A1D48_RS07620	COG3829	transcription factor binding
A1D48_RS07630	COG0531	amino acid
A1D48_RS07635	COG3457	Alanine racemase
A1D48_RS07640	COG0833	amino acid
A1D48_RS07680	COG1090	epimerase
A1D48_RS07685	COG0625	glutathione transferase activity
A1D48_RS07690	COG0625	glutathione transferase activity
A1D48_RS07695	COG0622	Phosphoesterase
A1D48_RS07705	COG1609	Transcriptional regulator
A1D48_RS07715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS07725	COG3037	sugar-specific permease SgaT UlaA
A1D48_RS07730	COG3959	Transketolase, thiamine diphosphate binding domain
A1D48_RS07735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A1D48_RS07740	COG1288	antiporter activity
A1D48_RS07765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1D48_RS07770	COG0471	metal ion transport
A1D48_RS07770	COG0490	domain, Protein
A1D48_RS07785	COG0436	Aminotransferase
A1D48_RS07795	COG0583	DNA-binding transcription factor activity
A1D48_RS07845	COG0839	Belongs to the complex I subunit 6 family
A1D48_RS07855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A1D48_RS07860	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A1D48_RS07875	COG2304	oxidoreductase activity
A1D48_RS07880	COG0784	Response regulator, receiver
A1D48_RS07880	COG0835	chemotaxis
A1D48_RS07890	COG2153	protein acetylation
A1D48_RS07895	COG4575	ribosome binding
A1D48_RS07900	COG1169	isochorismate synthase
A1D48_RS07990	COG1414	Transcriptional regulator
A1D48_RS08000	COG2271	Major facilitator Superfamily
A1D48_RS08025	COG0247	lactate metabolic process
A1D48_RS08035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A1D48_RS08040	COG2271	Major facilitator Superfamily
A1D48_RS08045	COG0584	glycerophosphoryl diester phosphodiesterase
A1D48_RS08050	COG0583	DNA-binding transcription factor activity
A1D48_RS08055	COG2814	Major facilitator Superfamily
A1D48_RS08060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1D48_RS08090	COG4948	Mandelate Racemase Muconate Lactonizing
A1D48_RS08115	COG0642	Histidine kinase
A1D48_RS08115	COG2198	Histidine kinase
A1D48_RS08145	COG4615	Cyclic peptide transporter
A1D48_RS08155	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1D48_RS08155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1D48_RS08160	COG3062	negative regulation of establishment of protein localization
A1D48_RS08170	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS08175	COG0348	domain, Protein
A1D48_RS08185	COG3043	anaerobic respiration
A1D48_RS08190	COG3005	denitrification pathway
A1D48_RS08200	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1D48_RS08205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1D48_RS08210	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1D48_RS08220	COG1138	Cytochrome C-type biogenesis protein
A1D48_RS08225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D48_RS08230	COG4235	cytochrome complex assembly
A1D48_RS08230	COG3088	subunit of a heme lyase
A1D48_RS08235	COG2197	response regulator
A1D48_RS08290	COG1061	Type III restriction enzyme res subunit
A1D48_RS08300	COG2814	Major facilitator Superfamily
A1D48_RS08315	COG4172	Belongs to the ABC transporter superfamily
A1D48_RS08320	COG4239	(ABC) transporter, permease
A1D48_RS08325	COG4174	ABC transporter (Permease)
A1D48_RS08330	COG4166	transmembrane transport
A1D48_RS08335	COG2200	EAL domain
A1D48_RS08340	COG0791	NLP P60 protein
A1D48_RS08350	COG0671	phosphoesterase, PA-phosphatase related
A1D48_RS08355	COG0523	cobalamin synthesis protein
A1D48_RS08390	COG1105	Belongs to the carbohydrate kinase PfkB family
A1D48_RS08395	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A1D48_RS08395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1D48_RS08395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1D48_RS08405	COG2855	membrane
A1D48_RS08410	COG0583	DNA-binding transcription factor activity
A1D48_RS08415	COG0833	amino acid
A1D48_RS08425	COG4771	TonB-dependent receptor
A1D48_RS08430	COG2271	Major facilitator Superfamily
A1D48_RS08435	COG0560	Phosphoserine phosphatase
A1D48_RS08440	COG1760	l-serine dehydratase
A1D48_RS08465	COG2311	Membrane
A1D48_RS08505	COG2949	membrane
A1D48_RS08515	COG1346	cytolysis
A1D48_RS08530	COG2271	Major facilitator Superfamily
A1D48_RS08545	COG0625	glutathione transferase activity
A1D48_RS08550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1D48_RS08565	COG1538	Outer membrane efflux protein
A1D48_RS08570	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS08575	COG0586	Pfam SNARE associated Golgi protein
A1D48_RS08590	COG1686	Belongs to the peptidase S11 family
A1D48_RS08595	COG0277	FAD linked oxidase domain protein
A1D48_RS08605	COG1732	Glycine betaine
A1D48_RS08610	COG1174	glycine betaine transport
A1D48_RS08615	COG1125	glycine betaine transport
A1D48_RS08620	COG1174	glycine betaine transport
A1D48_RS08635	COG3275	phosphorelay sensor kinase activity
A1D48_RS08645	COG4807	Protein conserved in bacteria
A1D48_RS08655	COG4808	Protein conserved in bacteria
A1D48_RS08680	COG3121	Chaperone
A1D48_RS08685	COG3188	usher protein
A1D48_RS08690	COG3539	Fimbrial protein
A1D48_RS08695	COG5455	response to cobalt ion
A1D48_RS08710	COG2188	Transcriptional regulator
A1D48_RS08715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D48_RS08720	COG1397	ADP-ribosylglycohydrolase
A1D48_RS08725	COG2211	Major facilitator Superfamily
A1D48_RS08730	COG1830	Aldolase
A1D48_RS08755	COG0826	peptidase U32
A1D48_RS08805	COG1413	lyase activity
A1D48_RS08810	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A1D48_RS08860	COG0745	RESPONSE REGULATOR receiver
A1D48_RS08865	COG2205	protein histidine kinase activity
A1D48_RS08895	COG0443	Heat shock 70 kDa protein
A1D48_RS08905	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A1D48_RS08910	COG3447	MASE1 domain protein
A1D48_RS08910	COG5001	Diguanylate cyclase
A1D48_RS08910	COG5002	protein histidine kinase activity
A1D48_RS08925	COG2982	Protein involved in outer membrane biogenesis
A1D48_RS08930	COG1253	flavin adenine dinucleotide binding
A1D48_RS08955	COG0463	Glycosyl transferase, family 2
A1D48_RS08960	COG1045	serine acetyltransferase
A1D48_RS08965	COG0438	transferase activity, transferring glycosyl groups
A1D48_RS08975	COG1216	Glycosyl transferase, family 2
A1D48_RS08980	COG0110	maltose O-acetyltransferase activity
A1D48_RS08985	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
A1D48_RS08990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D48_RS09000	COG0297	glycogen (starch) synthase activity
A1D48_RS09015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A1D48_RS09020	COG2244	polysaccharide biosynthetic process
A1D48_RS09025	COG2327	Polysaccharide pyruvyl transferase
A1D48_RS09165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D48_RS09170	COG0583	DNA-binding transcription factor activity
A1D48_RS09180	COG0531	amino acid
A1D48_RS09185	COG2925	Exonuclease
A1D48_RS09230	COG1289	transmembrane transporter activity
A1D48_RS09265	COG4656	Part of a membrane complex involved in electron transport
A1D48_RS09270	COG1454	alcohol dehydrogenase
A1D48_RS09270	COG1012	belongs to the aldehyde dehydrogenase family
A1D48_RS09285	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
A1D48_RS09300	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A1D48_RS09465	COG0640	Transcriptional regulator
A1D48_RS09470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A1D48_RS09485	COG0798	PFAM Bile acid sodium symporter
A1D48_RS09505	COG0534	Mate efflux family protein
A1D48_RS09530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A1D48_RS09580	COG0582	viral genome integration into host DNA
A1D48_RS09610	COG3423	Transcriptional regulator
A1D48_RS09625	COG0582	viral genome integration into host DNA
A1D48_RS09745	COG3381	protein complex oligomerization
A1D48_RS09805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A1D48_RS09820	COG2943	transferase activity, transferring hexosyl groups
A1D48_RS09825	COG5645	(Lipo)protein
A1D48_RS09845	COG1560	Kdo2-lipid A biosynthetic process
A1D48_RS09860	COG3038	cytochrome b561
A1D48_RS09900	COG2999	glutathione oxidoreductase activity
A1D48_RS09910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1D48_RS10010	COG1530	ribonuclease E activity
A1D48_RS10075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1D48_RS10080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A1D48_RS10085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A1D48_RS10095	COG0470	DNA polymerase III
A1D48_RS10100	COG0084	hydrolase, TatD family'
A1D48_RS10110	COG4773	Receptor
A1D48_RS10115	COG0537	adenosine 5'-monophosphoramidase activity
A1D48_RS10120	COG5633	Lipoprotein
A1D48_RS10145	COG1252	NADH dehydrogenase
A1D48_RS10150	COG3134	Outer membrane lipoprotein
A1D48_RS10155	COG1309	transcriptional regulator
A1D48_RS10165	COG1388	LysM domain
A1D48_RS10165	COG1376	ErfK ybiS ycfS ynhG family protein
A1D48_RS10170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A1D48_RS10175	COG4591	ABC-type transport system involved in lipoprotein release permease component
A1D48_RS10180	COG1136	(ABC) transporter
A1D48_RS10185	COG4591	ABC-type transport system involved in lipoprotein release permease component
A1D48_RS10205	COG1177	transmembrane transport
A1D48_RS10235	COG2850	peptidyl-arginine hydroxylation
A1D48_RS10250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A1D48_RS10280	COG0538	isocitrate dehydrogenase activity
A1D48_RS10380	COG0071	Belongs to the small heat shock protein (HSP20) family
A1D48_RS10395	COG3038	cytochrome b561
A1D48_RS10405	COG0747	negative chemotaxis
A1D48_RS10425	COG1124	(ABC) transporter
A1D48_RS10430	COG0668	transmembrane transport
A1D48_RS10445	COG3443	Belongs to the bacterial solute-binding protein 9 family
A1D48_RS10460	COG0789	Transcriptional regulator
A1D48_RS10475	COG1605	Chorismate mutase
A1D48_RS10490	COG3615	Tellurite resistance protein tehB
A1D48_RS10505	COG2261	transglycosylase associated protein
A1D48_RS10515	COG3042	response to heat
A1D48_RS10525	COG3189	MarR family transcriptional regulator
A1D48_RS10530	COG2807	transmembrane transport
A1D48_RS10535	COG2207	Transcriptional regulator
A1D48_RS10550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A1D48_RS10555	COG2199	diguanylate cyclase activity
A1D48_RS10570	COG2766	serine protein kinase
A1D48_RS10575	COG3713	MltA-interacting MipA family protein
A1D48_RS10580	COG0641	radical SAM
A1D48_RS10585	COG0656	L-ascorbic acid biosynthetic process
A1D48_RS10610	COG3139	Protein of unknown function (DUF1315)
A1D48_RS10615	COG1335	isochorismatase
A1D48_RS10620	COG0252	asparaginase activity
A1D48_RS10625	COG0616	signal peptide processing
A1D48_RS10630	COG0778	Nitroreductase
A1D48_RS10655	COG0494	nUDIX hydrolase
A1D48_RS10685	COG3724	N-succinylarginine dihydrolase activity
A1D48_RS10700	COG3678	ATP-independent chaperone mediated protein folding
A1D48_RS10705	COG0322	excinuclease ABC activity
A1D48_RS10715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1D48_RS10725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1D48_RS10730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1D48_RS10735	COG1447	Phosphotransferase system cellobiose-specific component IIA
A1D48_RS10740	COG2169	Transcriptional regulator
A1D48_RS10740	COG1917	Cupin 2, conserved barrel domain protein
A1D48_RS10745	COG1486	melibiose metabolic process
A1D48_RS10755	COG0753	catalase activity
A1D48_RS10765	COG1823	symporter activity
A1D48_RS10770	COG1988	membrane-bound metal-dependent
A1D48_RS10775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1D48_RS10785	COG3001	Fructosamine kinase
A1D48_RS10795	COG1105	Belongs to the carbohydrate kinase PfkB family
A1D48_RS10800	COG3137	Salt-induced outer membrane protein
A1D48_RS10865	COG0386	Belongs to the glutathione peroxidase family
A1D48_RS10875	COG0791	NLP P60 protein
A1D48_RS10890	COG4256	Hemin uptake protein
A1D48_RS10905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A1D48_RS10905	COG0574	Belongs to the PEP-utilizing enzyme family
A1D48_RS10910	COG0318	PFAM AMP-dependent synthetase and ligase
A1D48_RS10915	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A1D48_RS10920	COG0644	oxidoreductase
A1D48_RS10925	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A1D48_RS10930	COG2086	electron transfer activity
A1D48_RS10935	COG2207	Transcriptional regulator
A1D48_RS10935	COG1917	Cupin 2, conserved barrel domain protein
A1D48_RS10940	COG1960	acyl-CoA dehydrogenase activity
A1D48_RS10945	COG4670	ketone body catabolic process
A1D48_RS10960	COG2271	Major facilitator Superfamily
A1D48_RS10965	COG0738	Major facilitator superfamily
A1D48_RS10980	COG0628	permease
A1D48_RS10985	COG0247	lactate metabolic process
A1D48_RS10985	COG0277	FAD linked oxidase domain protein
A1D48_RS10990	COG2050	protein possibly involved in aromatic compounds catabolism
A1D48_RS11000	COG1823	symporter activity
A1D48_RS11005	COG0316	Belongs to the HesB IscA family
A1D48_RS11010	COG0719	Fe-S assembly protein
A1D48_RS11015	COG0396	ATPase activity
A1D48_RS11020	COG0719	Fe-S assembly protein
A1D48_RS11035	COG1376	ErfK ybiS ycfS ynhG family protein
A1D48_RS11040	COG4238	major outer membrane lipoprotein
A1D48_RS11060	COG0531	amino acid
A1D48_RS11065	COG2267	carboxylic ester hydrolase activity
A1D48_RS11075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D48_RS11110	COG3272	Protein of unknown function (DUF1722)
A1D48_RS11115	COG0789	Transcriptional regulator
A1D48_RS11295	COG0307	riboflavin synthase, alpha
A1D48_RS11300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A1D48_RS11305	COG2814	Major facilitator Superfamily
A1D48_RS11310	COG0583	DNA-binding transcription factor activity
A1D48_RS11335	COG0791	NLP P60 protein
A1D48_RS11340	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A1D48_RS11360	COG1902	pentaerythritol trinitrate reductase activity
A1D48_RS11365	COG1309	transcriptional regulator
A1D48_RS11370	COG3313	Fe-S protein
A1D48_RS11375	COG4989	oxidoreductase activity
A1D48_RS11390	COG1566	PFAM secretion protein HlyD family protein
A1D48_RS11415	COG3895	Periplasmic Protein
A1D48_RS11435	COG0625	glutathione transferase activity
A1D48_RS11445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A1D48_RS11495	COG0673	inositol 2-dehydrogenase activity
A1D48_RS11505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A1D48_RS11515	COG5339	Protein conserved in bacteria
A1D48_RS11540	COG2205	protein histidine kinase activity
A1D48_RS11545	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A1D48_RS11550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A1D48_RS11560	COG0745	RESPONSE REGULATOR receiver
A1D48_RS11565	COG3136	membrane protein required for alginate biosynthesis
A1D48_RS11570	COG0531	amino acid
A1D48_RS11580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A1D48_RS11585	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A1D48_RS11590	COG0628	permease
A1D48_RS11610	COG3591	Belongs to the peptidase S1B family
A1D48_RS11620	COG2814	Major facilitator Superfamily
A1D48_RS11625	COG0583	DNA-binding transcription factor activity
A1D48_RS11635	COG1940	carbohydrate kinase activity
A1D48_RS11675	COG3302	dmso reductase anchor subunit
A1D48_RS11680	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS11685	COG0243	molybdopterin cofactor binding
A1D48_RS11690	COG0243	molybdopterin cofactor binding
A1D48_RS11705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1D48_RS11725	COG1063	alcohol dehydrogenase
A1D48_RS11730	COG0477	Major facilitator Superfamily
A1D48_RS11735	COG0246	Mannitol dehydrogenase
A1D48_RS11745	COG1802	Transcriptional regulator
A1D48_RS11750	COG4221	oxidoreductase activity
A1D48_RS11765	COG3729	General stress protein
A1D48_RS11770	COG1546	Belongs to the CinA family
A1D48_RS11775	COG3111	PFAM Bacterial OB fold (BOF) protein
A1D48_RS11790	COG2814	Major facilitator Superfamily
A1D48_RS11825	COG0583	DNA-binding transcription factor activity
A1D48_RS11830	COG1012	belongs to the aldehyde dehydrogenase family
A1D48_RS11845	COG3781	membrane
A1D48_RS11870	COG1773	rubredoxin
A1D48_RS11900	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A1D48_RS11910	COG2186	Transcriptional regulator
A1D48_RS11915	COG1063	alcohol dehydrogenase
A1D48_RS11920	COG2271	Major facilitator Superfamily
A1D48_RS11945	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A1D48_RS11950	COG0251	oxidation-reduction process
A1D48_RS12025	COG1609	Transcriptional regulator
A1D48_RS12030	COG1757	Na H antiporter
A1D48_RS12035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A1D48_RS12050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A1D48_RS12065	COG1764	response to oxidative stress
A1D48_RS12085	COG1064	alcohol dehydrogenase
A1D48_RS12090	COG2864	formate dehydrogenase
A1D48_RS12095	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS12135	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A1D48_RS12140	COG1140	nitrate reductase beta subunit
A1D48_RS12145	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A1D48_RS12150	COG2181	nitrate reductase activity
A1D48_RS12190	COG4772	TonB-dependent receptor
A1D48_RS12200	COG2130	NADP-dependent
A1D48_RS12210	COG3238	Protein conserved in bacteria
A1D48_RS12250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A1D48_RS12255	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
A1D48_RS12280	COG0826	peptidase U32
A1D48_RS12285	COG1396	sequence-specific DNA binding
A1D48_RS12290	COG3135	benzoate transporter
A1D48_RS12300	COG0500	methyltransferase
A1D48_RS12305	COG1275	C4-dicarboxylate transporter malic acid transport protein
A1D48_RS12310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A1D48_RS12315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1D48_RS12325	COG3414	Phosphotransferase system galactitol-specific IIB component
A1D48_RS12330	COG3775	system Galactitol-specific IIC component
A1D48_RS12335	COG0434	BtpA family
A1D48_RS12340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS12345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A1D48_RS12350	COG1349	DNA-binding transcription factor activity
A1D48_RS12360	COG1304	FMN binding
A1D48_RS12365	COG2353	YceI-like domain
A1D48_RS12375	COG2272	Belongs to the type-B carboxylesterase lipase family
A1D48_RS12380	COG5383	Protein conserved in bacteria
A1D48_RS12385	COG0583	DNA-binding transcription factor activity
A1D48_RS12390	COG0840	transmembrane signaling receptor activity
A1D48_RS12430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D48_RS12435	COG0765	amino acid transport
A1D48_RS12445	COG0765	amino acid transport
A1D48_RS12455	COG0500	methyltransferase
A1D48_RS12460	COG3038	cytochrome b561
A1D48_RS12465	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A1D48_RS12470	COG1643	Atp-dependent helicase
A1D48_RS12485	COG3784	Protein of unknown function (DUF1318)
A1D48_RS12495	COG2911	Protein conserved in bacteria
A1D48_RS12500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A1D48_RS12505	COG3187	Heat shock protein
A1D48_RS12510	COG3042	response to heat
A1D48_RS12520	COG1013	pyruvate-flavodoxin oxidoreductase activity
A1D48_RS12520	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A1D48_RS12520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A1D48_RS12520	COG0674	pyruvate-flavodoxin oxidoreductase activity
A1D48_RS12535	COG2076	Multidrug Resistance protein
A1D48_RS12560	COG0513	Belongs to the DEAD box helicase family
A1D48_RS12575	COG0840	transmembrane signaling receptor activity
A1D48_RS12585	COG2840	Smr protein MutS2
A1D48_RS12605	COG3182	Iron-regulated membrane protein
A1D48_RS12610	COG0668	transmembrane transport
A1D48_RS12630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A1D48_RS12665	COG1309	transcriptional regulator
A1D48_RS12670	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS12675	COG0656	L-ascorbic acid biosynthetic process
A1D48_RS12680	COG0583	DNA-binding transcription factor activity
A1D48_RS12690	COG2814	Major facilitator Superfamily
A1D48_RS12695	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS12700	COG0814	amino acid
A1D48_RS12705	COG4948	Mandelate Racemase Muconate Lactonizing
A1D48_RS12720	COG0243	molybdopterin cofactor binding
A1D48_RS12725	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS12730	COG3302	dmso reductase anchor subunit
A1D48_RS12745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1D48_RS12750	COG4166	transmembrane transport
A1D48_RS12755	COG2866	Carboxypeptidase
A1D48_RS12760	COG4948	Mandelate Racemase Muconate Lactonizing
A1D48_RS12780	COG3106	COG3106 Predicted ATPase
A1D48_RS12785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A1D48_RS12795	COG1983	PspC domain protein
A1D48_RS12805	COG1842	Phage shock protein A
A1D48_RS12810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A1D48_RS12865	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1D48_RS12865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1D48_RS12880	COG5001	Diguanylate cyclase
A1D48_RS12890	COG1349	DNA-binding transcription factor activity
A1D48_RS12910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A1D48_RS12915	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A1D48_RS12925	COG0671	phosphoesterase, PA-phosphatase related
A1D48_RS12975	COG0616	signal peptide processing
A1D48_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS12995	COG0009	L-threonylcarbamoyladenylate synthase
A1D48_RS13035	COG3729	General stress protein
A1D48_RS13040	COG3685	Protein conserved in bacteria
A1D48_RS13045	COG3685	Protein conserved in bacteria
A1D48_RS13050	COG3546	catalase activity
A1D48_RS13055	COG3047	cAMP biosynthetic process
A1D48_RS13060	COG0727	PFAM Uncharacterised protein family (UPF0153)
A1D48_RS13085	COG2350	Protein conserved in bacteria
A1D48_RS13100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A1D48_RS13135	COG2095	MarC family integral membrane protein
A1D48_RS13140	COG1454	alcohol dehydrogenase
A1D48_RS13140	COG1012	belongs to the aldehyde dehydrogenase family
A1D48_RS13155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A1D48_RS13160	COG0745	RESPONSE REGULATOR receiver
A1D48_RS13165	COG1752	Esterase of the alpha-beta hydrolase superfamily
A1D48_RS13175	COG0788	formyltetrahydrofolate deformylase activity
A1D48_RS13220	COG2181	nitrate reductase activity
A1D48_RS13225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A1D48_RS13230	COG1140	nitrate reductase beta subunit
A1D48_RS13235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A1D48_RS13240	COG2223	nitrite transmembrane transporter activity
A1D48_RS13250	COG3850	Histidine kinase
A1D48_RS13255	COG2197	response regulator
A1D48_RS13260	COG4932	domain protein
A1D48_RS13265	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A1D48_RS13270	COG4572	Cation transport regulator
A1D48_RS13275	COG0387	Pfam Sodium calcium exchanger
A1D48_RS13325	COG0659	secondary active sulfate transmembrane transporter activity
A1D48_RS13340	COG0012	GTP binding
A1D48_RS13360	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
A1D48_RS13370	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
A1D48_RS13375	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A1D48_RS13380	COG1999	signal sequence binding
A1D48_RS13385	COG1773	rubredoxin
A1D48_RS13390	COG1271	oxidase subunit
A1D48_RS13395	COG1294	oxidase, subunit
A1D48_RS13405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A1D48_RS13430	COG1619	proteins homologs of microcin C7 resistance protein MccF
A1D48_RS13450	COG2719	SpoVR family
A1D48_RS13490	COG0179	Fumarylacetoacetate (FAA) hydrolase
A1D48_RS13505	COG2894	cell division
A1D48_RS13515	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A1D48_RS13530	COG3065	identical protein binding
A1D48_RS13540	COG1199	ATP-dependent helicase activity
A1D48_RS13545	COG0251	oxidation-reduction process
A1D48_RS13565	COG1760	l-serine dehydratase
A1D48_RS13570	COG2200	EAL domain
A1D48_RS13575	COG1253	flavin adenine dinucleotide binding
A1D48_RS13585	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D48_RS13585	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS13590	COG3715	PTS system
A1D48_RS13595	COG3716	PTS system mannose fructose sorbose family IID component
A1D48_RS13615	COG2226	methyltransferase
A1D48_RS13620	COG0768	penicillin binding
A1D48_RS13650	COG1414	Transcriptional regulator
A1D48_RS13655	COG2814	Major facilitator Superfamily
A1D48_RS13675	COG1956	GAF domain-containing protein
A1D48_RS13680	COG2995	paraquat-inducible protein a
A1D48_RS13685	COG3008	intermembrane lipid transfer
A1D48_RS13725	COG5562	phage envelope protein
A1D48_RS13755	COG4680	protein conserved in bacteria
A1D48_RS13760	COG5499	transcription regulator containing HTH domain
A1D48_RS13780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A1D48_RS13820	COG1276	copper resistance
A1D48_RS13825	COG2372	response to copper ion
A1D48_RS13835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1D48_RS13840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A1D48_RS13845	COG1770	oligopeptidase
A1D48_RS13850	COG2979	Protein of unknown function (DUF533)
A1D48_RS13860	COG3141	response to X-ray
A1D48_RS13870	COG0800	Aldolase
A1D48_RS13875	COG0129	dihydroxy-acid dehydratase activity
A1D48_RS13880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A1D48_RS13890	COG1737	Transcriptional regulator
A1D48_RS13900	COG1560	Kdo2-lipid A biosynthetic process
A1D48_RS13910	COG0739	heme binding
A1D48_RS13915	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A1D48_RS13925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1D48_RS13960	COG0494	nUDIX hydrolase
A1D48_RS13970	COG1335	isochorismatase
A1D48_RS13975	COG1801	Protein of unknown function DUF72
A1D48_RS13980	COG3788	relative of glutathione S-transferase, MAPEG superfamily
A1D48_RS14005	COG3102	Protein conserved in bacteria
A1D48_RS14020	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A1D48_RS14125	COG1528	Iron-storage protein
A1D48_RS14140	COG1528	Iron-storage protein
A1D48_RS14150	COG0814	amino acid
A1D48_RS14155	COG3012	SEC-C Motif Domain Protein
A1D48_RS14155	COG3318	Belongs to the UPF0149 family
A1D48_RS14200	COG2197	response regulator
A1D48_RS14215	COG2197	response regulator
A1D48_RS14220	COG1126	abc transporter atp-binding protein
A1D48_RS14225	COG0765	amino acid transport
A1D48_RS14235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D48_RS14295	COG0425	Belongs to the sulfur carrier protein TusA family
A1D48_RS14400	COG5475	Uncharacterized small protein (DUF2158)
A1D48_RS14405	COG2354	Protein conserved in bacteria
A1D48_RS14410	COG0697	spore germination
A1D48_RS14415	COG3727	T/G mismatch-specific endonuclease activity
A1D48_RS14420	COG0270	DNA (cytosine-5-)-methyltransferase activity
A1D48_RS14425	COG1418	mRNA catabolic process
A1D48_RS14435	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A1D48_RS14480	COG1702	phosphate starvation-inducible protein PhoH
A1D48_RS14510	COG1309	transcriptional regulator
A1D48_RS14515	COG3729	General stress protein
A1D48_RS14535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1D48_RS14540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A1D48_RS14540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A1D48_RS14545	COG4232	protein-disulfide reductase activity
A1D48_RS14600	COG3971	2-oxopent-4-enoate hydratase activity
A1D48_RS14615	COG3384	dioxygenase
A1D48_RS14620	COG1012	belongs to the aldehyde dehydrogenase family
A1D48_RS14630	COG1846	Transcriptional regulator
A1D48_RS14635	COG2368	4-hydroxyphenylacetate
A1D48_RS14660	COG0745	RESPONSE REGULATOR receiver
A1D48_RS14665	COG2205	protein histidine kinase activity
A1D48_RS14720	COG0670	Belongs to the BI1 family
A1D48_RS14740	COG1881	PFAM PEBP family protein
A1D48_RS14755	COG1832	CoA-binding protein
A1D48_RS14770	COG0210	DNA helicase
A1D48_RS14775	COG3304	Inner membrane component domain
A1D48_RS14780	COG1289	transmembrane transporter activity
A1D48_RS14785	COG3070	regulator of competence-specific genes
A1D48_RS14805	COG1067	ATP-dependent peptidase activity
A1D48_RS14815	COG3130	regulation of translation
A1D48_RS14820	COG3009	Protein conserved in bacteria
A1D48_RS14825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A1D48_RS14825	COG3008	intermembrane lipid transfer
A1D48_RS14830	COG2995	paraquat-inducible protein a
A1D48_RS14835	COG0488	(ABC) transporter
A1D48_RS14845	COG0633	Ferredoxin
A1D48_RS14845	COG3217	Mosc domain protein beta barrel domain protein
A1D48_RS14860	COG0308	aminopeptidase N
A1D48_RS15035	COG3772	lysozyme
A1D48_RS15045	COG0484	heat shock protein binding
A1D48_RS15160	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A1D48_RS15175	COG0582	viral genome integration into host DNA
A1D48_RS15185	COG1115	amino acid carrier protein
A1D48_RS15200	COG1522	sequence-specific DNA binding
A1D48_RS15205	COG0017	Asparaginyl-tRNA synthetase
A1D48_RS15210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A1D48_RS15215	COG1448	Aminotransferase
A1D48_RS15220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1D48_RS15225	COG3108	Peptidase M15
A1D48_RS15235	COG2989	Protein conserved in bacteria
A1D48_RS15245	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
A1D48_RS15255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A1D48_RS15260	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A1D48_RS15265	COG3173	Aminoglycoside phosphotransferase
A1D48_RS15280	COG3214	Protein conserved in bacteria
A1D48_RS15285	COG1663	tetraacyldisaccharide 4'-kinase activity
A1D48_RS15295	COG2333	competence protein COMEC
A1D48_RS15295	COG0658	competence protein
A1D48_RS15305	COG0539	negative regulation of cytoplasmic translation
A1D48_RS15320	COG0501	Belongs to the peptidase M48B family
A1D48_RS15335	COG2323	membrane
A1D48_RS15340	COG1944	ATP diphosphatase activity
A1D48_RS15345	COG2116	formate transmembrane transporter activity
A1D48_RS15350	COG1882	Formate acetyltransferase
A1D48_RS15365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A1D48_RS15370	COG0531	amino acid
A1D48_RS15380	COG3302	dmso reductase anchor subunit
A1D48_RS15385	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS15390	COG0243	molybdopterin cofactor binding
A1D48_RS15400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A1D48_RS15425	COG0492	ferredoxin-NADP+ reductase activity
A1D48_RS15430	COG4988	ABC transporter
A1D48_RS15435	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A1D48_RS15455	COG0583	DNA-binding transcription factor activity
A1D48_RS15465	COG1335	isochorismatase
A1D48_RS15495	COG0542	response to heat
A1D48_RS15505	COG1278	Cold shock
A1D48_RS15510	COG0577	efflux transmembrane transporter activity
A1D48_RS15510	COG1136	(ABC) transporter
A1D48_RS15515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1D48_RS15520	COG2990	Protein conserved in bacteria
A1D48_RS15525	COG3593	DNA synthesis involved in DNA repair
A1D48_RS15535	COG2431	L-lysine efflux transmembrane transporter activity
A1D48_RS15545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1D48_RS15550	COG0028	Belongs to the TPP enzyme family
A1D48_RS15555	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A1D48_RS15560	COG0702	epimerase
A1D48_RS15565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1D48_RS15570	COG3023	N-Acetylmuramoyl-L-alanine amidase
A1D48_RS15585	COG1126	abc transporter atp-binding protein
A1D48_RS15590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D48_RS15595	COG4215	(ABC) transporter
A1D48_RS15600	COG4160	amino acid transport
A1D48_RS15605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D48_RS15640	COG1177	transmembrane transport
A1D48_RS15645	COG1176	ABC-type spermidine putrescine transport system, permease component I
A1D48_RS15650	COG3842	ATPase activity
A1D48_RS15655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A1D48_RS15705	COG3226	Transcriptional regulator
A1D48_RS15710	COG0738	Major facilitator superfamily
A1D48_RS15715	COG0561	phosphatase activity
A1D48_RS15720	COG2814	Major facilitator Superfamily
A1D48_RS15725	COG0671	phosphoesterase, PA-phosphatase related
A1D48_RS15730	COG1349	DNA-binding transcription factor activity
A1D48_RS15735	COG1686	Belongs to the peptidase S11 family
A1D48_RS15740	COG0625	glutathione transferase activity
A1D48_RS15745	COG2133	pyrroloquinoline quinone binding
A1D48_RS15795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A1D48_RS15800	COG1882	Formate acetyltransferase
A1D48_RS15805	COG0561	phosphatase activity
A1D48_RS15830	COG0488	(ABC) transporter
A1D48_RS15835	COG1376	ErfK ybiS ycfS ynhG family protein
A1D48_RS15840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A1D48_RS15855	COG2194	sulfuric ester hydrolase activity
A1D48_RS15860	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A1D48_RS15875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D48_RS15880	COG0765	amino acid transport
A1D48_RS15885	COG1126	abc transporter atp-binding protein
A1D48_RS15890	COG0668	transmembrane transport
A1D48_RS15900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A1D48_RS15910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A1D48_RS15920	COG0513	Belongs to the DEAD box helicase family
A1D48_RS15925	COG1012	belongs to the aldehyde dehydrogenase family
A1D48_RS15925	COG1454	alcohol dehydrogenase
A1D48_RS15930	COG3958	Transketolase
A1D48_RS15935	COG3959	Transketolase, thiamine diphosphate binding domain
A1D48_RS15940	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS15945	COG2271	Major facilitator Superfamily
A1D48_RS15950	COG0583	DNA-binding transcription factor activity
A1D48_RS15955	COG1309	transcriptional regulator
A1D48_RS15965	COG1131	(ABC) transporter
A1D48_RS15970	COG0842	Transport permease protein
A1D48_RS15975	COG0842	Transport permease protein
A1D48_RS15985	COG3568	Endonuclease Exonuclease Phosphatase
A1D48_RS15990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A1D48_RS15995	COG0392	lysyltransferase activity
A1D48_RS16015	COG0670	Belongs to the BI1 family
A1D48_RS16025	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A1D48_RS16035	COG0521	Mo-molybdopterin cofactor biosynthetic process
A1D48_RS16090	COG1881	PFAM PEBP family protein
A1D48_RS16120	COG4677	pectinesterase activity
A1D48_RS16130	COG0561	phosphatase activity
A1D48_RS16140	COG4149	molybdate abc transporter
A1D48_RS16145	COG0725	ABC transporter, periplasmic molybdate-binding protein
A1D48_RS16155	COG3585	molybdate ion transport
A1D48_RS16155	COG2005	Transcriptional regulator
A1D48_RS16160	COG1119	ATPase activity
A1D48_RS16185	COG2017	converts alpha-aldose to the beta-anomer
A1D48_RS16200	COG1120	ATPase activity
A1D48_RS16205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D48_RS16210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A1D48_RS16265	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A1D48_RS16270	COG2885	chlorophyll binding
A1D48_RS16280	COG3064	Membrane
A1D48_RS16285	COG0848	biopolymer transport protein
A1D48_RS16290	COG0811	peptide transport
A1D48_RS16295	COG0824	Thioesterase
A1D48_RS16300	COG3790	cyd operon protein YbgE
A1D48_RS16305	COG4890	Cyd operon protein YbgT
A1D48_RS16310	COG1294	oxidase, subunit
A1D48_RS16315	COG1271	oxidase subunit
A1D48_RS16325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A1D48_RS16335	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1D48_RS16340	COG0567	Dehydrogenase, E1 component
A1D48_RS16355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A1D48_RS16380	COG3180	Ammonia monooxygenase
A1D48_RS16405	COG1216	Glycosyl transferase, family 2
A1D48_RS16445	COG0582	viral genome integration into host DNA
A1D48_RS16460	COG1984	allophanate hydrolase subunit 2
A1D48_RS16465	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A1D48_RS16515	COG2205	protein histidine kinase activity
A1D48_RS16520	COG0745	RESPONSE REGULATOR receiver
A1D48_RS16530	COG1982	Orn Lys Arg decarboxylase major
A1D48_RS16535	COG0531	amino acid
A1D48_RS16545	COG0033	Phosphoglucomutase
A1D48_RS16555	COG0596	Alpha beta hydrolase
A1D48_RS16570	COG0735	belongs to the Fur family
A1D48_RS16575	COG0583	DNA-binding transcription factor activity
A1D48_RS16580	COG1053	succinate dehydrogenase
A1D48_RS16625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A1D48_RS16630	COG1940	carbohydrate kinase activity
A1D48_RS16630	COG1846	Transcriptional regulator
A1D48_RS16635	COG0647	UMP catabolic process
A1D48_RS16640	COG0367	asparagine synthase
A1D48_RS16685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1D48_RS16695	COG1702	phosphate starvation-inducible protein PhoH
A1D48_RS16720	COG0765	amino acid transport
A1D48_RS16725	COG0765	amino acid transport
A1D48_RS16730	COG1126	abc transporter atp-binding protein
A1D48_RS16745	COG0443	Heat shock 70 kDa protein
A1D48_RS16750	COG2214	Heat shock protein DnaJ domain protein
A1D48_RS16760	COG2214	Heat shock protein DnaJ domain protein
A1D48_RS16775	COG2888	peptidyl-tyrosine sulfation
A1D48_RS16780	COG3290	protein histidine kinase activity
A1D48_RS16780	COG3829	transcription factor binding
A1D48_RS16810	COG1466	dna polymerase III delta subunit
A1D48_RS16820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A1D48_RS16830	COG0799	negative regulation of ribosome biogenesis
A1D48_RS16840	COG0768	penicillin binding
A1D48_RS16845	COG0772	Belongs to the SEDS family
A1D48_RS16855	COG1686	Belongs to the peptidase S11 family
A1D48_RS16870	COG0583	DNA-binding transcription factor activity
A1D48_RS16885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1D48_RS16910	COG3069	C4-dicarboxylate transmembrane transporter activity
A1D48_RS16915	COG4565	transcriptional regulatory protein
A1D48_RS16920	COG3290	protein histidine kinase activity
A1D48_RS16930	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
A1D48_RS16940	COG2301	Belongs to the HpcH HpaI aldolase family
A1D48_RS16945	COG3051	citrate lyase alpha subunit
A1D48_RS16960	COG0471	metal ion transport
A1D48_RS16965	COG3719	Belongs to the RNase T2 family
A1D48_RS16975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A1D48_RS16980	COG1063	alcohol dehydrogenase
A1D48_RS17000	COG0243	molybdopterin cofactor binding
A1D48_RS17020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A1D48_RS17030	COG0583	DNA-binding transcription factor activity
A1D48_RS17035	COG3969	phosphoadenosine phosphosulfate
A1D48_RS17040	COG1475	DNA binding
A1D48_RS17045	COG0436	Aminotransferase
A1D48_RS17050	COG0371	Dehydrogenase
A1D48_RS17055	COG2879	small protein
A1D48_RS17060	COG1966	Carbon starvation protein
A1D48_RS17070	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS17075	COG3433	isochorismatase activity
A1D48_RS17075	COG1535	isochorismatase
A1D48_RS17080	COG1021	2,3-dihydroxybenzoate-AMP ligase
A1D48_RS17085	COG1169	isochorismate synthase
A1D48_RS17090	COG4592	Periplasmic binding protein
A1D48_RS17100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D48_RS17105	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1D48_RS17110	COG1120	ATPase activity
A1D48_RS17115	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A1D48_RS17120	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A1D48_RS17120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1D48_RS17125	COG3251	PFAM MbtH domain protein
A1D48_RS17130	COG2382	esterase
A1D48_RS17135	COG4771	TonB-dependent receptor
A1D48_RS17140	COG2977	Belongs to the P-Pant transferase superfamily
A1D48_RS17165	COG2315	Protein conserved in bacteria
A1D48_RS17190	COG3716	PTS system mannose fructose sorbose family IID component
A1D48_RS17200	COG2222	sugar isomerase
A1D48_RS17205	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A1D48_RS17205	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A1D48_RS17220	COG0668	transmembrane transport
A1D48_RS17225	COG1113	amino acid transport
A1D48_RS17235	COG3059	membrane
A1D48_RS17245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1D48_RS17250	COG2207	Transcriptional regulator
A1D48_RS17260	COG5002	protein histidine kinase activity
A1D48_RS17270	COG2246	polysaccharide biosynthetic process
A1D48_RS17360	COG2501	S4 domain
A1D48_RS17365	COG1988	membrane-bound metal-dependent
A1D48_RS17385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A1D48_RS17400	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A1D48_RS17405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A1D48_RS17410	COG0549	Belongs to the carbamate kinase family
A1D48_RS17420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A1D48_RS17425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A1D48_RS17430	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A1D48_RS17435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A1D48_RS17440	COG3257	ureidoglycine aminohydrolase activity
A1D48_RS17445	COG1929	Belongs to the glycerate kinase type-1 family
A1D48_RS17450	COG2233	PERMEase
A1D48_RS17460	COG1953	Uracil, thiamine, allantoin
A1D48_RS17470	COG2084	Dehydrogenase
A1D48_RS17475	COG3622	Belongs to the hyi family
A1D48_RS17480	COG3960	tartronate-semialdehyde synthase activity
A1D48_RS17515	COG1464	Belongs to the NlpA lipoprotein family
A1D48_RS17525	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A1D48_RS17530	COG4181	ATPase activity
A1D48_RS17535	COG2755	lipolytic protein G-D-S-L family
A1D48_RS17540	COG0300	oxidoreductase activity
A1D48_RS17545	COG3118	belongs to the thioredoxin family
A1D48_RS17550	COG0390	transport system, permease component
A1D48_RS17555	COG4619	ABC transporter
A1D48_RS17560	COG0330	HflC and HflK could
A1D48_RS17565	COG1585	Membrane protein implicated in regulation of membrane protease activity
A1D48_RS17575	COG2217	Heavy metal translocating P-type atpase
A1D48_RS17585	COG3735	TraB family
A1D48_RS17600	COG2223	nitrite transmembrane transporter activity
A1D48_RS17605	COG4651	solute:proton antiporter activity
A1D48_RS17605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A1D48_RS17610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D48_RS17665	COG2832	Protein of unknown function (DUF454)
A1D48_RS17670	COG3923	Primosomal replication protein n
A1D48_RS17680	COG5464	transposase or invertase
A1D48_RS17685	COG3264	Mechanosensitive ion channel
A1D48_RS17685	COG1196	nuclear chromosome segregation
A1D48_RS17690	COG1309	transcriptional regulator
A1D48_RS17695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1D48_RS17700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1D48_RS17715	COG0110	maltose O-acetyltransferase activity
A1D48_RS17735	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A1D48_RS17745	COG3695	enzyme binding
A1D48_RS17750	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A1D48_RS17755	COG1946	Acyl-CoA thioesterase
A1D48_RS17760	COG0004	ammonium transporteR
A1D48_RS17765	COG0347	Belongs to the P(II) protein family
A1D48_RS17770	COG1132	(ABC) transporter
A1D48_RS17775	COG1132	(ABC) transporter
A1D48_RS17780	COG1522	sequence-specific DNA binding
A1D48_RS17790	COG0561	phosphatase activity
A1D48_RS17795	COG4533	DNA binding
A1D48_RS17805	COG0824	Thioesterase
A1D48_RS17810	COG1555	photosystem II stabilization
A1D48_RS17815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A1D48_RS17825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A1D48_RS17850	COG0271	Belongs to the BolA IbaG family
A1D48_RS17860	COG3056	Lipoprotein
A1D48_RS17865	COG2223	nitrite transmembrane transporter activity
A1D48_RS17870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A1D48_RS17875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A1D48_RS17880	COG1845	cytochrome c oxidase, subunit III
A1D48_RS17885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A1D48_RS17905	COG2814	Major facilitator Superfamily
A1D48_RS17935	COG2188	Transcriptional regulator
A1D48_RS17970	COG0142	geranyltranstransferase activity
A1D48_RS17980	COG0667	Aldo Keto reductase
A1D48_RS17985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A1D48_RS17990	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A1D48_RS18005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A1D48_RS18005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A1D48_RS18015	COG4238	major outer membrane lipoprotein
A1D48_RS18050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A1D48_RS18060	COG1862	Preprotein translocase
A1D48_RS18085	COG0450	alkyl hydroperoxide reductase
A1D48_RS18090	COG0366	Alpha amylase catalytic
A1D48_RS18105	COG5002	protein histidine kinase activity
A1D48_RS18115	COG0420	3'-5' exonuclease activity
A1D48_RS18120	COG0419	ATPase involved in DNA repair
A1D48_RS18125	COG2814	Major facilitator Superfamily
A1D48_RS18130	COG1940	carbohydrate kinase activity
A1D48_RS18145	COG4126	flavin adenine dinucleotide binding
A1D48_RS18165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A1D48_RS18170	COG3706	GGDEF domain
A1D48_RS18220	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A1D48_RS18230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A1D48_RS18245	COG0113	porphobilinogen synthase activity
A1D48_RS18280	COG1280	lysine exporter protein (LysE YggA)
A1D48_RS18300	COG1294	oxidase, subunit
A1D48_RS18305	COG1271	oxidase subunit
A1D48_RS18325	COG2814	Major facilitator Superfamily
A1D48_RS18335	COG0789	Transcriptional regulator
A1D48_RS18390	COG2200	EAL domain
A1D48_RS18415	COG3539	Fimbrial protein
A1D48_RS18420	COG3121	Chaperone
A1D48_RS18425	COG3188	usher protein
A1D48_RS18480	COG2195	Cleaves the N-terminal amino acid of tripeptides
A1D48_RS18485	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A1D48_RS18490	COG1690	Belongs to the RtcB family
A1D48_RS18500	COG3034	peptidoglycan biosynthetic process
A1D48_RS18505	COG0121	glutamine amidotransferase
A1D48_RS18520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1D48_RS18550	COG1522	sequence-specific DNA binding
A1D48_RS18670	COG3209	COG3209 Rhs family protein
A1D48_RS18745	COG2885	chlorophyll binding
A1D48_RS18745	COG3047	cAMP biosynthetic process
A1D48_RS18860	COG2226	methyltransferase
A1D48_RS18870	COG0741	lytic transglycosylase activity
A1D48_RS18870	COG1388	LysM domain
A1D48_RS18875	COG2226	methyltransferase
A1D48_RS18885	COG2814	Major facilitator Superfamily
A1D48_RS18890	COG0583	DNA-binding transcription factor activity
A1D48_RS18895	COG0656	L-ascorbic acid biosynthetic process
A1D48_RS18930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A1D48_RS18955	COG1720	tRNA m6t6A37 methyltransferase activity
A1D48_RS18965	COG3015	lipoprotein NlpE involved in copper resistance
A1D48_RS18970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A1D48_RS18985	COG4568	rho-dependent transcription termination
A1D48_RS18995	COG0346	lactoylglutathione lyase activity
A1D48_RS19000	COG1982	Orn Lys Arg decarboxylase major
A1D48_RS19060	COG0575	Belongs to the CDS family
A1D48_RS19125	COG0477	Major facilitator Superfamily
A1D48_RS19135	COG3835	regulator
A1D48_RS19160	COG2860	membrane
A1D48_RS19190	COG3539	Fimbrial protein
A1D48_RS19195	COG3539	Fimbrial protein
A1D48_RS19200	COG3121	Chaperone
A1D48_RS19205	COG3188	usher protein
A1D48_RS19225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1D48_RS19230	COG1120	ATPase activity
A1D48_RS19235	COG4774	siderophore transport
A1D48_RS19240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A1D48_RS19245	COG1643	Atp-dependent helicase
A1D48_RS19250	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A1D48_RS19270	COG0617	tRNA 3'-terminal CCA addition
A1D48_RS19275	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A1D48_RS19300	COG3121	Chaperone
A1D48_RS19305	COG3188	usher protein
A1D48_RS19310	COG3539	Fimbrial protein
A1D48_RS19330	COG0726	polysaccharide deacetylase
A1D48_RS19335	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS19355	COG3539	Fimbrial protein
A1D48_RS19360	COG0842	Transport permease protein
A1D48_RS19365	COG1131	(ABC) transporter
A1D48_RS19370	COG0288	reversible hydration of carbon dioxide
A1D48_RS19380	COG4993	Dehydrogenase
A1D48_RS19385	COG2132	Multicopper oxidase
A1D48_RS19405	COG1349	DNA-binding transcription factor activity
A1D48_RS19480	COG3064	Membrane
A1D48_RS19495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1D48_RS19500	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1D48_RS19505	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A1D48_RS19520	COG2211	Major facilitator Superfamily
A1D48_RS19525	COG3940	Belongs to the glycosyl hydrolase 43 family
A1D48_RS19530	COG3725	Membrane protein required for beta-lactamase induction
A1D48_RS19550	COG4969	Belongs to the N-Me-Phe pilin family
A1D48_RS19555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A1D48_RS19560	COG1459	type II secretion system
A1D48_RS19585	COG0583	DNA-binding transcription factor activity
A1D48_RS19590	COG0667	Aldo Keto reductase
A1D48_RS19595	COG0494	nUDIX hydrolase
A1D48_RS19615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A1D48_RS19620	COG0849	cell division
A1D48_RS19645	COG0772	Belongs to the SEDS family
A1D48_RS19660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A1D48_RS19670	COG0768	penicillin binding
A1D48_RS19760	COG0586	Pfam SNARE associated Golgi protein
A1D48_RS19800	COG0417	DNA replication proofreading
A1D48_RS19830	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A1D48_RS19875	COG3119	arylsulfatase activity
A1D48_RS19900	COG2271	Major facilitator Superfamily
A1D48_RS19910	COG0644	oxidoreductase
A1D48_RS19940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A1D48_RS20025	COG5016	pyruvate
A1D48_RS20025	COG0511	ligase activity, forming carbon-carbon bonds
A1D48_RS20060	COG1047	Peptidyl-prolyl cis-trans
A1D48_RS20075	COG0196	riboflavin kinase activity
A1D48_RS20100	COG0583	DNA-binding transcription factor activity
A1D48_RS20120	COG0641	radical SAM
A1D48_RS20125	COG3119	arylsulfatase activity
A1D48_RS20135	COG0737	Belongs to the 5'-nucleotidase family
A1D48_RS20150	COG0583	DNA-binding transcription factor activity
A1D48_RS20170	COG3121	Chaperone
A1D48_RS20175	COG3539	Fimbrial protein
A1D48_RS20190	COG3188	usher protein
A1D48_RS20255	COG4735	regulation of single-species biofilm formation
A1D48_RS20260	COG1584	GPR1 FUN34 yaaH family protein
A1D48_RS20265	COG0521	Mo-molybdopterin cofactor biosynthetic process
A1D48_RS20275	COG1115	amino acid carrier protein
A1D48_RS20285	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A1D48_RS20295	COG0527	aspartate kinase activity
A1D48_RS20295	COG0460	homoserine dehydrogenase
A1D48_RS20305	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A1D48_RS20315	COG0745	RESPONSE REGULATOR receiver
A1D48_RS20335	COG3121	Chaperone
A1D48_RS20355	COG4452	Inner membrane protein CreD
A1D48_RS20360	COG2205	protein histidine kinase activity
A1D48_RS20365	COG0745	RESPONSE REGULATOR receiver
A1D48_RS20370	COG3045	CreA protein
A1D48_RS20375	COG3708	Transcriptional regulator
A1D48_RS20375	COG2207	Transcriptional regulator
A1D48_RS20410	COG0488	(ABC) transporter
A1D48_RS20425	COG0560	Phosphoserine phosphatase
A1D48_RS20435	COG3726	membrane protein affecting hemolysin expression
A1D48_RS20455	COG3539	Fimbrial protein
A1D48_RS20460	COG3121	Chaperone
A1D48_RS20465	COG3188	usher protein
A1D48_RS20495	COG1328	CTP reductase activity
A1D48_RS20500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A1D48_RS20505	COG0084	hydrolase, TatD family'
A1D48_RS20510	COG4667	esterase of the alpha-beta hydrolase superfamily
A1D48_RS20520	COG2823	Periplasmic or secreted lipoprotein
A1D48_RS20530	COG1011	Hydrolase
A1D48_RS20540	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A1D48_RS20570	COG3706	GGDEF domain
A1D48_RS20575	COG4114	ferric iron reductase
A1D48_RS20580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A1D48_RS20585	COG2197	response regulator
A1D48_RS20590	COG2197	response regulator
A1D48_RS20595	COG2966	Psort location CytoplasmicMembrane, score
A1D48_RS20610	COG1484	DNA-dependent DNA replication
A1D48_RS20625	COG0840	transmembrane signaling receptor activity
A1D48_RS20630	COG1966	Carbon starvation protein
A1D48_RS20635	COG2879	small protein
A1D48_RS20640	COG0523	cobalamin synthesis protein
A1D48_RS20650	COG1280	lysine exporter protein (LysE YggA)
A1D48_RS20655	COG3586	endonuclease activity
A1D48_RS20670	COG1012	belongs to the aldehyde dehydrogenase family
A1D48_RS20675	COG5464	transposase or invertase
A1D48_RS20685	COG2733	membrane
A1D48_RS20690	COG0477	Major facilitator Superfamily
A1D48_RS20695	COG3366	ferrous iron transmembrane transporter activity
A1D48_RS20700	COG0700	Nucleoside recognition
A1D48_RS20705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A1D48_RS20710	COG0583	DNA-binding transcription factor activity
A1D48_RS20735	COG2186	Transcriptional regulator
A1D48_RS20745	COG0412	Dienelactone hydrolase
A1D48_RS20780	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A1D48_RS20805	COG2894	cell division
A1D48_RS20835	COG3468	outer membrane autotransporter barrel domain protein
A1D48_RS20855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A1D48_RS20860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A1D48_RS20995	COG3423	Transcriptional regulator
A1D48_RS21000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A1D48_RS21015	COG0641	radical SAM
A1D48_RS21065	COG4227	nucleotidyltransferase activity
A1D48_RS21070	COG0494	nUDIX hydrolase
A1D48_RS21090	COG1064	alcohol dehydrogenase
A1D48_RS21095	COG3265	gluconokinase activity
A1D48_RS21100	COG1063	alcohol dehydrogenase
A1D48_RS21105	COG1028	Short-chain dehydrogenase reductase Sdr
A1D48_RS21110	COG2610	gluconate transmembrane transporter activity
A1D48_RS21115	COG1609	Transcriptional regulator
A1D48_RS21120	COG0795	lipopolysaccharide-transporting ATPase activity
A1D48_RS21125	COG0795	lipopolysaccharide-transporting ATPase activity
A1D48_RS21145	COG2927	DNA polymerase III (CHI subunit)
A1D48_RS21185	COG2731	YhcH YjgK YiaL family protein
A1D48_RS21215	COG1288	antiporter activity
A1D48_RS21220	COG1438	arginine binding
A1D48_RS21270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D48_RS21270	COG1263	PTS System
A1D48_RS21275	COG0366	Alpha amylase catalytic
A1D48_RS21290	COG2026	Addiction module toxin, RelE StbE family
A1D48_RS21295	COG3077	Addiction module antitoxin, RelB DinJ family
A1D48_RS21300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS21300	COG3711	transcriptional antiterminator
A1D48_RS21315	COG3964	amidohydrolase
A1D48_RS21350	COG0312	modulator of DNA gyrase
A1D48_RS21360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A1D48_RS21375	COG3964	amidohydrolase
A1D48_RS21380	COG2271	Major facilitator Superfamily
A1D48_RS21385	COG2105	PFAM AIG2 family protein
A1D48_RS21405	COG1253	flavin adenine dinucleotide binding
A1D48_RS21420	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A1D48_RS21440	COG1733	regulation of RNA biosynthetic process
A1D48_RS21445	COG0702	epimerase
A1D48_RS21450	COG0697	spore germination
A1D48_RS21460	COG1113	amino acid transport
A1D48_RS21465	COG0545	Peptidyl-prolyl cis-trans isomerase
A1D48_RS21475	COG3061	Opacity-associated protein A
A1D48_RS21490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A1D48_RS21510	COG3477	response to acidic pH
A1D48_RS21555	COG1073	alpha beta
A1D48_RS21560	COG3650	response to hydrogen peroxide
A1D48_RS21570	COG1960	acyl-CoA dehydrogenase activity
A1D48_RS21575	COG0754	glutathionylspermidine amidase activity
A1D48_RS21580	COG5463	Belongs to the UPF0441 family
A1D48_RS21585	COG3766	membrane
A1D48_RS21600	COG1842	Phage shock protein A
A1D48_RS21605	COG3789	protein conserved in bacteria
A1D48_RS21615	COG0557	exoribonuclease II activity
A1D48_RS21630	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A1D48_RS21635	COG0330	HflC and HflK could
A1D48_RS21640	COG0330	HflC and HflK could
A1D48_RS21645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A1D48_RS21670	COG0802	atpase or kinase
A1D48_RS21675	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A1D48_RS21675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A1D48_RS21700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1D48_RS21720	COG3264	Mechanosensitive ion channel
A1D48_RS21720	COG1511	domain protein
A1D48_RS21740	COG1053	succinate dehydrogenase
A1D48_RS21745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A1D48_RS21775	COG5510	response to toxic substance
A1D48_RS21820	COG0531	amino acid
A1D48_RS21825	COG3030	protein affecting phage T7 exclusion by the F plasmid
A1D48_RS21830	COG1027	Aspartate ammonia-lyase
A1D48_RS21835	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A1D48_RS21850	COG1309	transcriptional regulator
A1D48_RS21870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A1D48_RS21870	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A1D48_RS21875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A1D48_RS21880	COG1063	alcohol dehydrogenase
A1D48_RS21885	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A1D48_RS21890	COG1063	alcohol dehydrogenase
A1D48_RS21895	COG3716	PTS system mannose fructose sorbose family IID component
A1D48_RS21905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D48_RS21910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1D48_RS21910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1D48_RS21920	COG0671	phosphoesterase, PA-phosphatase related
A1D48_RS21955	COG2197	response regulator
A1D48_RS21960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A1D48_RS21985	COG3381	protein complex oligomerization
A1D48_RS21990	COG3302	dmso reductase anchor subunit
A1D48_RS21995	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS22000	COG0243	molybdopterin cofactor binding
A1D48_RS22005	COG3290	protein histidine kinase activity
A1D48_RS22010	COG4565	transcriptional regulatory protein
A1D48_RS22020	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A1D48_RS22025	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A1D48_RS22025	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A1D48_RS22040	COG2169	Transcriptional regulator
A1D48_RS22045	COG1982	Orn Lys Arg decarboxylase major
A1D48_RS22050	COG2207	Transcriptional regulator
A1D48_RS22055	COG0531	amino acid
A1D48_RS22085	COG2824	Alkylphosphonate utilization operon protein PhnA
A1D48_RS22090	COG2764	glyoxalase bleomycin resistance protein dioxygenase
A1D48_RS22110	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A1D48_RS22115	COG1301	dicarboxylic acid transport
A1D48_RS22120	COG4235	cytochrome complex assembly
A1D48_RS22125	COG3088	subunit of a heme lyase
A1D48_RS22130	COG1138	Cytochrome C-type biogenesis protein
A1D48_RS22135	COG3301	Polysulphide reductase, NrfD
A1D48_RS22140	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS22145	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A1D48_RS22160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A1D48_RS22165	COG3162	membrane
A1D48_RS22175	COG1346	cytolysis
A1D48_RS22180	COG1380	Effector of murein hydrolase LrgA
A1D48_RS22185	COG0583	DNA-binding transcription factor activity
A1D48_RS22190	COG0025	NhaP-type Na H and K H
A1D48_RS22200	COG2252	PERMEase
A1D48_RS22225	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A1D48_RS22300	COG2315	Protein conserved in bacteria
A1D48_RS22355	COG0735	belongs to the Fur family
A1D48_RS22370	COG0534	Mate efflux family protein
A1D48_RS22380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A1D48_RS22425	COG3833	ABC-type maltose transport systems, permease component
A1D48_RS22435	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1D48_RS22460	COG0527	aspartate kinase activity
A1D48_RS22540	COG2246	polysaccharide biosynthetic process
A1D48_RS22570	COG5301	cellulose 1,4-beta-cellobiosidase activity
A1D48_RS22575	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A1D48_RS22610	COG3122	Protein conserved in bacteria
A1D48_RS22655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A1D48_RS22695	COG0151	Belongs to the GarS family
A1D48_RS22760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A1D48_RS22765	COG2104	thiamine diphosphate biosynthetic process
A1D48_RS22835	COG0250	Participates in transcription elongation, termination and antitermination
A1D48_RS22890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A1D48_RS22955	COG0583	DNA-binding transcription factor activity
A1D48_RS23000	COG2207	Transcriptional regulator
A1D48_RS23010	COG0371	Dehydrogenase
A1D48_RS23015	COG3738	Protein conserved in bacteria
A1D48_RS23030	COG0737	Belongs to the 5'-nucleotidase family
A1D48_RS23045	COG0668	transmembrane transport
A1D48_RS23050	COG0527	aspartate kinase activity
A1D48_RS23050	COG0460	homoserine dehydrogenase
A1D48_RS23055	COG0626	cystathionine gamma-synthase activity
A1D48_RS23075	COG3209	COG3209 Rhs family protein
A1D48_RS23085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A1D48_RS23090	COG1609	Transcriptional regulator
A1D48_RS23095	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A1D48_RS23110	COG1575	Belongs to the MenA family. Type 1 subfamily
A1D48_RS23125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A1D48_RS23135	COG1494	fructose-1,6-bisphosphatase
A1D48_RS23145	COG3152	Membrane
A1D48_RS23200	COG1070	Carbohydrate kinase
A1D48_RS23220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A1D48_RS23235	COG2211	Major facilitator Superfamily
A1D48_RS23260	COG3678	ATP-independent chaperone mediated protein folding
A1D48_RS23265	COG0745	RESPONSE REGULATOR receiver
A1D48_RS23270	COG2205	protein histidine kinase activity
A1D48_RS23285	COG2258	MOSC domain
A1D48_RS23290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A1D48_RS23300	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A1D48_RS23350	COG1454	alcohol dehydrogenase
A1D48_RS23365	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A1D48_RS23400	COG0437	4 iron, 4 sulfur cluster binding
A1D48_RS23405	COG2864	formate dehydrogenase
A1D48_RS23420	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
A1D48_RS23430	COG4680	protein conserved in bacteria
A1D48_RS23435	COG5499	transcription regulator containing HTH domain
A1D48_RS23440	COG0456	acetyltransferase
A1D48_RS23455	COG1011	Hydrolase
A1D48_RS23460	COG1349	DNA-binding transcription factor activity
A1D48_RS23465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D48_RS23475	COG3684	Belongs to the aldolase LacD family
A1D48_RS23485	COG2017	converts alpha-aldose to the beta-anomer
A1D48_RS23490	COG1501	Belongs to the glycosyl hydrolase 31 family
A1D48_RS23535	COG0561	phosphatase activity
A1D48_RS23605	COG0204	Acyl-transferase
A1D48_RS23620	COG3084	Protein conserved in bacteria
A1D48_RS23625	COG0746	molybdenum cofactor guanylyltransferase activity
A1D48_RS23630	COG1763	Mo-molybdopterin cofactor biosynthetic process
A1D48_RS23675	COG1739	Uncharacterized protein family UPF0029
A1D48_RS23705	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A1D48_RS23720	COG0805	protein transport
A1D48_RS23765	COG0641	radical SAM
A1D48_RS23785	COG0561	phosphatase activity
A1D48_RS23790	COG2267	carboxylic ester hydrolase activity
A1D48_RS23795	COG1280	lysine exporter protein (LysE YggA)
A1D48_RS23800	COG1280	lysine exporter protein (LysE YggA)
A1D48_RS23850	COG1011	Hydrolase
A1D48_RS23925	COG2959	enzyme of heme biosynthesis
A1D48_RS23930	COG3071	HemY protein
A1D48_RS23975	COG2244	polysaccharide biosynthetic process
A1D48_RS23980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A1D48_RS23985	COG0456	acetyltransferase
A1D48_RS23990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A1D48_RS23990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A1D48_RS23995	COG1088	dTDP-glucose 4,6-dehydratase activity
A1D48_RS24000	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A1D48_RS24030	COG3118	belongs to the thioredoxin family
A1D48_RS24110	COG3978	acetolactate synthase activity
A1D48_RS24170	COG2186	Transcriptional regulator
A1D48_RS24175	COG0477	Major facilitator Superfamily
A1D48_RS24180	COG1609	Transcriptional regulator
A1D48_RS24185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1D48_RS24195	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1D48_RS24230	COG1522	sequence-specific DNA binding
A1D48_RS24235	COG0716	FMN binding
A1D48_RS24255	COG3312	ion transport
A1D48_RS24320	COG4533	DNA binding
A1D48_RS24325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A1D48_RS24330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1D48_RS24330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1D48_RS24330	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A1D48_RS24335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A1D48_RS24340	COG0573	inorganic phosphate transmembrane transporter activity
A1D48_RS24345	COG0581	inorganic phosphate transmembrane transporter activity
A1D48_RS24355	COG0704	Plays a role in the regulation of phosphate uptake
A1D48_RS24360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1D48_RS24370	COG2252	PERMEase
A1D48_RS24375	COG0431	NADPH-dependent FMN reductase
A1D48_RS24380	COG2091	lysine biosynthetic process via aminoadipic acid
A1D48_RS24480	COG0582	viral genome integration into host DNA
A1D48_RS24505	COG3209	COG3209 Rhs family protein
A1D48_RS24510	COG3209	COG3209 Rhs family protein