locus-tag	class	description
CXL12_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
CXL12_RS00035	COG2271	Major facilitator Superfamily
CXL12_RS00040	COG0561	phosphatase activity
CXL12_RS00045	COG2186	Transcriptional regulator
CXL12_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
CXL12_RS00055	COG0800	Aldolase
CXL12_RS00065	COG2271	Major facilitator Superfamily
CXL12_RS00070	COG0784	Response regulator, receiver
CXL12_RS00070	COG2198	Histidine kinase
CXL12_RS00070	COG2205	protein histidine kinase activity
CXL12_RS00075	COG1879	ABC-type sugar transport system periplasmic component
CXL12_RS00080	COG0745	RESPONSE REGULATOR receiver
CXL12_RS00085	COG3005	denitrification pathway
CXL12_RS00100	COG1858	cytochrome C peroxidase
CXL12_RS00110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXL12_RS00115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXL12_RS00120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXL12_RS00130	COG1138	Cytochrome C-type biogenesis protein
CXL12_RS00135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL12_RS00140	COG4235	cytochrome complex assembly
CXL12_RS00140	COG3088	subunit of a heme lyase
CXL12_RS00145	COG0823	Involved in the tonB-independent uptake of proteins
CXL12_RS00150	COG5645	(Lipo)protein
CXL12_RS00160	COG0071	Belongs to the small heat shock protein (HSP20) family
CXL12_RS00170	COG2149	membrane
CXL12_RS00180	COG0641	radical SAM
CXL12_RS00190	COG2610	gluconate transmembrane transporter activity
CXL12_RS00195	COG0583	DNA-binding transcription factor activity
CXL12_RS00205	COG2814	Major facilitator Superfamily
CXL12_RS00235	COG0028	Belongs to the TPP enzyme family
CXL12_RS00240	COG0440	acetolactate synthase activity
CXL12_RS00245	COG1349	DNA-binding transcription factor activity
CXL12_RS00255	COG0738	Major facilitator superfamily
CXL12_RS00290	COG2188	Transcriptional regulator
CXL12_RS00295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS00295	COG3711	transcriptional antiterminator
CXL12_RS00300	COG3414	Phosphotransferase system galactitol-specific IIB component
CXL12_RS00305	COG3775	system Galactitol-specific IIC component
CXL12_RS00340	COG2723	6-phospho-beta-galactosidase activity
CXL12_RS00360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL12_RS00360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS00365	COG3715	PTS system
CXL12_RS00370	COG3716	PTS system mannose fructose sorbose family IID component
CXL12_RS00385	COG5464	transposase or invertase
CXL12_RS00415	COG1335	isochorismatase
CXL12_RS00430	COG1470	cell adhesion involved in biofilm formation
CXL12_RS00430	COG1388	LysM domain
CXL12_RS00445	COG3710	Transcriptional regulator
CXL12_RS00460	COG2771	luxR family
CXL12_RS00495	COG2211	Major facilitator Superfamily
CXL12_RS00500	COG1501	Belongs to the glycosyl hydrolase 31 family
CXL12_RS00505	COG2982	Protein involved in outer membrane biogenesis
CXL12_RS00510	COG2233	PERMEase
CXL12_RS00515	COG0786	glutamate:sodium symporter activity
CXL12_RS00525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXL12_RS00530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXL12_RS00535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXL12_RS00555	COG2860	membrane
CXL12_RS00565	COG0583	DNA-binding transcription factor activity
CXL12_RS00605	COG1561	YicC-like family, N-terminal region
CXL12_RS00635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXL12_RS00665	COG1519	Transferase
CXL12_RS00670	COG0859	PFAM glycosyl transferase family 9
CXL12_RS00675	COG0438	transferase activity, transferring glycosyl groups
CXL12_RS00750	COG1216	Glycosyl transferase, family 2
CXL12_RS00755	COG2861	carbohydrate metabolic process
CXL12_RS00760	COG4942	peptidase
CXL12_RS00770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXL12_RS00775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXL12_RS00795	COG2271	Major facilitator Superfamily
CXL12_RS00810	COG1609	Transcriptional regulator
CXL12_RS00815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CXL12_RS00825	COG2186	Transcriptional regulator
CXL12_RS00855	COG3722	fumarate hydratase activity
CXL12_RS00865	COG2213	PTS system mannitol-specific
CXL12_RS00865	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS00870	COG0625	glutathione transferase activity
CXL12_RS00880	COG3276	selenocysteine insertion sequence binding
CXL12_RS00885	COG1940	carbohydrate kinase activity
CXL12_RS00890	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS00905	COG0235	Class ii aldolase
CXL12_RS00910	COG3623	hexulose-6-phosphate isomerase
CXL12_RS00915	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CXL12_RS00920	COG1070	Carbohydrate kinase
CXL12_RS00925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXL12_RS00930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CXL12_RS00935	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXL12_RS00945	COG2731	YhcH YjgK YiaL family protein
CXL12_RS00955	COG1414	Transcriptional regulator
CXL12_RS00960	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXL12_RS00965	COG3977	Valine--pyruvate aminotransferase
CXL12_RS00970	COG0366	Alpha amylase catalytic
CXL12_RS00975	COG2992	FlgJ-related protein
CXL12_RS00980	COG1609	Transcriptional regulator
CXL12_RS00980	COG2207	Transcriptional regulator
CXL12_RS00995	COG1070	Carbohydrate kinase
CXL12_RS01000	COG4682	membrane
CXL12_RS01005	COG3274	enterobacterial common antigen metabolic process
CXL12_RS01030	COG2801	Transposase and inactivated derivatives
CXL12_RS01040	COG0469	pyruvate kinase activity
CXL12_RS01050	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXL12_RS01055	COG2379	hydroxypyruvate reductase
CXL12_RS01060	COG2271	Major facilitator Superfamily
CXL12_RS01065	COG0148	phosphopyruvate hydratase activity
CXL12_RS01085	COG1278	Cold shock
CXL12_RS01090	COG2944	sequence-specific DNA binding
CXL12_RS01105	COG2885	chlorophyll binding
CXL12_RS01110	COG0243	molybdopterin cofactor binding
CXL12_RS01115	COG0456	acetyltransferase
CXL12_RS01120	COG2818	Glycosylase
CXL12_RS01125	COG5571	outer membrane autotransporter
CXL12_RS01190	COG0747	negative chemotaxis
CXL12_RS01195	COG0601	transmembrane transport
CXL12_RS01200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXL12_RS01205	COG0444	Belongs to the ABC transporter superfamily
CXL12_RS01210	COG4608	Belongs to the ABC transporter superfamily
CXL12_RS01215	COG0814	amino acid
CXL12_RS01255	COG1215	transferase activity, transferring glycosyl groups
CXL12_RS01280	COG2199	diguanylate cyclase activity
CXL12_RS01280	COG2200	EAL domain
CXL12_RS01295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS01300	COG2200	EAL domain
CXL12_RS01305	COG2982	Protein involved in outer membrane biogenesis
CXL12_RS01310	COG0477	Major facilitator Superfamily
CXL12_RS01315	COG1295	ribonuclease BN
CXL12_RS01320	COG0583	DNA-binding transcription factor activity
CXL12_RS01325	COG2197	response regulator
CXL12_RS01345	COG2188	Transcriptional regulator
CXL12_RS01350	COG2222	sugar isomerase
CXL12_RS01355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS01360	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXL12_RS01375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXL12_RS01380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CXL12_RS01420	COG0306	phosphate transporter
CXL12_RS01425	COG2081	HI0933 family
CXL12_RS01430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXL12_RS01435	COG0842	Transport permease protein
CXL12_RS01435	COG1129	ABC transporter
CXL12_RS01440	COG0842	Transport permease protein
CXL12_RS01450	COG2091	lysine biosynthetic process via aminoadipic acid
CXL12_RS01455	COG0628	permease
CXL12_RS01470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CXL12_RS01490	COG3714	YhhN family
CXL12_RS01500	COG3776	membrane
CXL12_RS01505	COG0742	ribosomal rna small subunit methyltransferase
CXL12_RS01510	COG0552	protein localization to endoplasmic reticulum
CXL12_RS01515	COG2884	Cell division ATP-binding protein ftsE
CXL12_RS01520	COG2177	Part of the ABC transporter FtsEX involved in
CXL12_RS01595	COG0584	glycerophosphoryl diester phosphodiesterase
CXL12_RS01605	COG0405	Gamma-glutamyltransferase
CXL12_RS01610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CXL12_RS01625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS01630	COG1247	-acetyltransferase
CXL12_RS01635	COG0673	inositol 2-dehydrogenase activity
CXL12_RS01640	COG1741	Belongs to the pirin family
CXL12_RS01645	COG1609	Transcriptional regulator
CXL12_RS01650	COG3265	gluconokinase activity
CXL12_RS01655	COG2610	gluconate transmembrane transporter activity
CXL12_RS01670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CXL12_RS01690	COG0058	SHG alpha-glucan phosphorylase activity
CXL12_RS01695	COG1414	Transcriptional regulator
CXL12_RS01700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CXL12_RS01705	COG0129	dihydroxy-acid dehydratase activity
CXL12_RS01715	COG0371	Dehydrogenase
CXL12_RS01730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXL12_RS01745	COG1349	DNA-binding transcription factor activity
CXL12_RS01750	COG4650	regulator
CXL12_RS01760	COG1690	Belongs to the RtcB family
CXL12_RS01780	COG0058	SHG alpha-glucan phosphorylase activity
CXL12_RS01785	COG1640	4-alpha-glucanotransferase
CXL12_RS01790	COG2610	gluconate transmembrane transporter activity
CXL12_RS01810	COG5464	transposase or invertase
CXL12_RS01825	COG1918	ferrous iron import across plasma membrane
CXL12_RS01835	COG2183	response to ionizing radiation
CXL12_RS01840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXL12_RS01860	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXL12_RS01870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CXL12_RS01875	COG1011	Hydrolase
CXL12_RS01885	COG0494	nUDIX hydrolase
CXL12_RS01890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CXL12_RS01895	COG4972	Pilus assembly protein
CXL12_RS01900	COG3166	PFAM Fimbrial assembly family protein
CXL12_RS01915	COG4796	Type ii and iii secretion system protein
CXL12_RS01935	COG3266	domain, Protein
CXL12_RS01940	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CXL12_RS01945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXL12_RS01985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CXL12_RS02020	COG1289	transmembrane transporter activity
CXL12_RS02030	COG1765	OsmC-like protein
CXL12_RS02035	COG3954	Phosphoribulokinase
CXL12_RS02045	COG0429	hydrolase of the alpha beta-hydrolase fold
CXL12_RS02060	COG0488	(ABC) transporter
CXL12_RS02075	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CXL12_RS02080	COG1047	Peptidyl-prolyl cis-trans
CXL12_RS02095	COG0545	Peptidyl-prolyl cis-trans isomerase
CXL12_RS02100	COG2964	Protein conserved in bacteria
CXL12_RS02170	COG0051	transcription antitermination factor activity, RNA binding
CXL12_RS02195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CXL12_RS02275	COG0201	protein transport
CXL12_RS02315	COG0789	Transcriptional regulator
CXL12_RS02320	COG3036	rescue of stalled ribosome
CXL12_RS02350	COG0758	DNA mediated transformation
CXL12_RS02360	COG0551	DNA topoisomerase type I activity
CXL12_RS02380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXL12_RS02425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXL12_RS02430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXL12_RS02435	COG1309	transcriptional regulator
CXL12_RS02450	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CXL12_RS02475	COG4145	pantothenate transmembrane transporter activity
CXL12_RS02480	COG3924	membrane
CXL12_RS02485	COG0439	Biotin carboxylase
CXL12_RS02490	COG0511	ligase activity, forming carbon-carbon bonds
CXL12_RS02505	COG0604	alcohol dehydrogenase
CXL12_RS02510	COG2199	diguanylate cyclase activity
CXL12_RS02510	COG2200	EAL domain
CXL12_RS02525	COG1077	Cell shape determining protein MreB Mrl
CXL12_RS02530	COG1792	Involved in formation and maintenance of cell shape
CXL12_RS02535	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CXL12_RS02550	COG3164	Protein of unknown function
CXL12_RS02555	COG0312	modulator of DNA gyrase
CXL12_RS02560	COG0583	DNA-binding transcription factor activity
CXL12_RS02580	COG2732	(Barnase) inhibitor
CXL12_RS02605	COG2188	Transcriptional regulator
CXL12_RS02615	COG0471	metal ion transport
CXL12_RS02620	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXL12_RS02625	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXL12_RS02635	COG5016	pyruvate
CXL12_RS02635	COG0511	ligase activity, forming carbon-carbon bonds
CXL12_RS02655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXL12_RS02660	COG3105	Protein conserved in bacteria
CXL12_RS02665	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CXL12_RS02680	COG0625	glutathione transferase activity
CXL12_RS02685	COG2969	positive regulation of protein catabolic process
CXL12_RS02715	COG2731	YhcH YjgK YiaL family protein
CXL12_RS02720	COG0402	S-adenosylhomocysteine deaminase activity
CXL12_RS02725	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CXL12_RS02730	COG4804	nuclease activity
CXL12_RS02735	COG0493	'glutamate synthase
CXL12_RS02740	COG0067	glutamate synthase
CXL12_RS02740	COG0069	glutamate synthase activity
CXL12_RS02740	COG0070	glutamate synthase
CXL12_RS02750	COG1242	4 iron, 4 sulfur cluster binding
CXL12_RS02755	COG5002	protein histidine kinase activity
CXL12_RS02755	COG2198	Histidine kinase
CXL12_RS02755	COG0784	Response regulator, receiver
CXL12_RS02760	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CXL12_RS02770	COG0515	serine threonine protein kinase
CXL12_RS02780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS02805	COG1137	ATPase activity
CXL12_RS02810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CXL12_RS02815	COG3117	lipopolysaccharide transmembrane transporter activity
CXL12_RS02820	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CXL12_RS02830	COG0530	calcium, potassium:sodium antiporter activity
CXL12_RS02835	COG1127	ABC transporter
CXL12_RS02840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CXL12_RS02845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXL12_RS02850	COG2854	intermembrane phospholipid transfer
CXL12_RS02855	COG3113	response to antibiotic
CXL12_RS02860	COG5007	Belongs to the BolA IbaG family
CXL12_RS02870	COG3423	Transcriptional regulator
CXL12_RS02875	COG0142	geranyltranstransferase activity
CXL12_RS02890	COG0697	spore germination
CXL12_RS02900	COG2027	D-alanyl-D-alanine carboxypeptidase
CXL12_RS02910	COG1534	Rna-binding protein
CXL12_RS02930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CXL12_RS02940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXL12_RS03005	COG0513	Belongs to the DEAD box helicase family
CXL12_RS03010	COG0814	amino acid
CXL12_RS03015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXL12_RS03020	COG0826	peptidase U32
CXL12_RS03025	COG0826	peptidase U32
CXL12_RS03030	COG3154	lipid carrier protein
CXL12_RS03035	COG3153	acetyltransferase
CXL12_RS03050	COG0693	protein deglycase activity
CXL12_RS03055	COG0702	epimerase
CXL12_RS03060	COG2823	Periplasmic or secreted lipoprotein
CXL12_RS03075	COG3107	peptidoglycan biosynthetic process
CXL12_RS03080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CXL12_RS03090	COG1063	alcohol dehydrogenase
CXL12_RS03095	COG3775	system Galactitol-specific IIC component
CXL12_RS03100	COG3414	Phosphotransferase system galactitol-specific IIB component
CXL12_RS03105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS03120	COG2721	sulfolactate sulfo-lyase activity
CXL12_RS03130	COG2084	Dehydrogenase
CXL12_RS03135	COG1929	Belongs to the glycerate kinase type-1 family
CXL12_RS03160	COG0583	DNA-binding transcription factor activity
CXL12_RS03180	COG1882	Formate acetyltransferase
CXL12_RS03185	COG1760	l-serine dehydratase
CXL12_RS03190	COG0814	amino acid
CXL12_RS03205	COG1741	Belongs to the pirin family
CXL12_RS03210	COG0583	DNA-binding transcription factor activity
CXL12_RS03215	COG3152	Membrane
CXL12_RS03220	COG0435	Glutathione S-transferase
CXL12_RS03225	COG2259	Doxx family
CXL12_RS03235	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CXL12_RS03240	COG4575	ribosome binding
CXL12_RS03245	COG1422	Protein of unknown function (DUF1090)
CXL12_RS03255	COG0586	Pfam SNARE associated Golgi protein
CXL12_RS03275	COG0673	inositol 2-dehydrogenase activity
CXL12_RS03280	COG2949	membrane
CXL12_RS03285	COG1451	nucleotide metabolic process
CXL12_RS03295	COG0446	pyridine nucleotide-disulphide oxidoreductase
CXL12_RS03295	COG1902	pentaerythritol trinitrate reductase activity
CXL12_RS03310	COG0840	transmembrane signaling receptor activity
CXL12_RS03315	COG0840	transmembrane signaling receptor activity
CXL12_RS03320	COG1695	Transcriptional regulator
CXL12_RS03325	COG2375	cellular response to nickel ion
CXL12_RS03350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CXL12_RS03370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXL12_RS03385	COG4991	sh3 domain protein
CXL12_RS03395	COG3025	triphosphatase activity
CXL12_RS03415	COG2268	Band 7 protein
CXL12_RS03420	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXL12_RS03465	COG3384	dioxygenase
CXL12_RS03470	COG0754	glutathionylspermidine amidase activity
CXL12_RS03490	COG0494	nUDIX hydrolase
CXL12_RS03495	COG3151	Protein conserved in bacteria
CXL12_RS03500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXL12_RS03505	COG3150	esterase
CXL12_RS03515	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXL12_RS03520	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXL12_RS03525	COG0642	Histidine kinase
CXL12_RS03535	COG3111	PFAM Bacterial OB fold (BOF) protein
CXL12_RS03540	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXL12_RS03590	COG0471	metal ion transport
CXL12_RS03600	COG1979	alcohol dehydrogenase
CXL12_RS03605	COG2207	Transcriptional regulator
CXL12_RS03630	COG0848	biopolymer transport protein
CXL12_RS03635	COG1028	Short-chain dehydrogenase reductase Sdr
CXL12_RS03660	COG0840	transmembrane signaling receptor activity
CXL12_RS03675	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXL12_RS03680	COG0437	4 iron, 4 sulfur cluster binding
CXL12_RS03685	COG5557	Pfam Polysulphide reductase, NrfD
CXL12_RS03690	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CXL12_RS03695	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXL12_RS03700	COG1773	rubredoxin
CXL12_RS03710	COG0298	carbon dioxide binding
CXL12_RS03715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXL12_RS03725	COG0625	glutathione transferase activity
CXL12_RS03730	COG0754	glutathionylspermidine amidase activity
CXL12_RS03745	COG0246	Mannitol dehydrogenase
CXL12_RS03755	COG2271	Major facilitator Superfamily
CXL12_RS03780	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS03785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXL12_RS03795	COG0531	amino acid
CXL12_RS03890	COG1811	Na channel or pump
CXL12_RS03900	COG1982	Orn Lys Arg decarboxylase major
CXL12_RS03905	COG2211	Major facilitator Superfamily
CXL12_RS03935	COG3171	Protein conserved in bacteria
CXL12_RS03945	COG0252	asparaginase activity
CXL12_RS03955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXL12_RS03970	COG0762	integral membrane protein
CXL12_RS03975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CXL12_RS03980	COG2805	Type II/IV secretion system protein
CXL12_RS04005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CXL12_RS04010	COG2356	endonuclease I
CXL12_RS04020	COG2814	Major facilitator Superfamily
CXL12_RS04045	COG1166	arginine decarboxylase activity
CXL12_RS04055	COG2186	Transcriptional regulator
CXL12_RS04065	COG0246	Mannitol dehydrogenase
CXL12_RS04070	COG1063	alcohol dehydrogenase
CXL12_RS04075	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXL12_RS04080	COG2731	YhcH YjgK YiaL family protein
CXL12_RS04085	COG2267	carboxylic ester hydrolase activity
CXL12_RS04100	COG0501	Belongs to the peptidase M48B family
CXL12_RS04105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXL12_RS04110	COG1122	ATPase activity
CXL12_RS04115	COG1122	ATPase activity
CXL12_RS04150	COG0191	fructose-bisphosphate aldolase activity
CXL12_RS04155	COG0668	transmembrane transport
CXL12_RS04165	COG2968	Membrane
CXL12_RS04185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXL12_RS04190	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CXL12_RS04215	COG0006	proline dipeptidase activity
CXL12_RS04220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXL12_RS04225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXL12_RS04255	COG2723	6-phospho-beta-galactosidase activity
CXL12_RS04265	COG1272	protein, Hemolysin III
CXL12_RS04335	COG4942	peptidase
CXL12_RS04375	COG3188	usher protein
CXL12_RS04410	COG0814	amino acid
CXL12_RS04425	COG0183	Belongs to the thiolase family
CXL12_RS04440	COG1028	Short-chain dehydrogenase reductase Sdr
CXL12_RS04445	COG2814	Major facilitator Superfamily
CXL12_RS04450	COG1794	racemase activity, acting on amino acids and derivatives
CXL12_RS04455	COG0583	DNA-binding transcription factor activity
CXL12_RS04465	COG1609	Transcriptional regulator
CXL12_RS04495	COG0667	Aldo Keto reductase
CXL12_RS04505	COG0861	Integral membrane protein TerC family
CXL12_RS04540	COG2165	general secretion pathway protein
CXL12_RS04545	COG4795	General secretion pathway protein
CXL12_RS04555	COG4967	type IV pilus modification protein PilV
CXL12_RS04560	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CXL12_RS04565	COG1025	Belongs to the peptidase M16 family
CXL12_RS04570	COG1074	ATP-dependent DNA helicase activity
CXL12_RS04575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CXL12_RS04585	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXL12_RS04600	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CXL12_RS04605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CXL12_RS04610	COG2962	Rard protein
CXL12_RS04615	COG2166	iron-sulfur cluster assembly
CXL12_RS04620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXL12_RS04630	COG0583	DNA-binding transcription factor activity
CXL12_RS04635	COG2363	Small membrane protein
CXL12_RS04645	COG1349	DNA-binding transcription factor activity
CXL12_RS04665	COG0738	Major facilitator superfamily
CXL12_RS04670	COG0235	Class ii aldolase
CXL12_RS04675	COG1454	alcohol dehydrogenase
CXL12_RS04690	COG1760	l-serine dehydratase
CXL12_RS04695	COG0814	amino acid
CXL12_RS04700	COG1611	Belongs to the LOG family
CXL12_RS04720	COG3098	single-species biofilm formation
CXL12_RS04730	COG0716	FMN binding
CXL12_RS04740	COG2271	Major facilitator Superfamily
CXL12_RS04745	COG4948	Mandelate Racemase Muconate Lactonizing
CXL12_RS04750	COG4948	Mandelate Racemase Muconate Lactonizing
CXL12_RS04755	COG1929	Belongs to the glycerate kinase type-1 family
CXL12_RS04760	COG2205	protein histidine kinase activity
CXL12_RS04760	COG3437	response regulator, receiver
CXL12_RS04760	COG4999	Histidine kinase
CXL12_RS04760	COG3850	Histidine kinase
CXL12_RS04770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXL12_RS04795	COG3539	Fimbrial protein
CXL12_RS04800	COG3121	Chaperone
CXL12_RS04805	COG3188	usher protein
CXL12_RS04810	COG3539	Fimbrial protein
CXL12_RS04815	COG3956	TIGRFAM MazG family protein
CXL12_RS04830	COG0602	queuosine metabolic process
CXL12_RS04835	COG0321	lipoyl(octanoyl) transferase activity
CXL12_RS04835	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CXL12_RS04840	COG0720	synthase
CXL12_RS04850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CXL12_RS04870	COG1203	CRISPR-associated helicase, Cas3
CXL12_RS04885	COG1857	crispr-associated protein
CXL12_RS04900	COG1518	maintenance of DNA repeat elements
CXL12_RS04905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXL12_RS04910	COG2234	aminopeptidase activity
CXL12_RS04980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CXL12_RS04985	COG0163	prenyltransferase activity
CXL12_RS04995	COG1349	DNA-binding transcription factor activity
CXL12_RS05000	COG2084	Dehydrogenase
CXL12_RS05010	COG0235	Class ii aldolase
CXL12_RS05015	COG3622	Belongs to the hyi family
CXL12_RS05020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL12_RS05025	COG2610	gluconate transmembrane transporter activity
CXL12_RS05035	COG0477	Major facilitator Superfamily
CXL12_RS05115	COG2207	Transcriptional regulator
CXL12_RS05205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL12_RS05295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXL12_RS05300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXL12_RS05305	COG1121	(ABC) transporter
CXL12_RS05325	COG0309	Hydrogenase expression formation protein (HypE)
CXL12_RS05330	COG0409	Hydrogenase expression formation protein
CXL12_RS05335	COG0298	carbon dioxide binding
CXL12_RS05340	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CXL12_RS05360	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXL12_RS05365	COG0651	ATP synthesis coupled electron transport
CXL12_RS05370	COG0650	Formate hydrogenlyase subunit 4
CXL12_RS05375	COG3261	NADH dehydrogenase
CXL12_RS05375	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CXL12_RS05380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXL12_RS05385	COG3260	NADH ubiquinone oxidoreductase 20
CXL12_RS05395	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXL12_RS05405	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXL12_RS05410	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CXL12_RS05430	COG0517	IMP dehydrogenase activity
CXL12_RS05430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CXL12_RS05435	COG1349	DNA-binding transcription factor activity
CXL12_RS05440	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS05445	COG1028	Short-chain dehydrogenase reductase Sdr
CXL12_RS05455	COG3732	PTS system glucitol sorbitol-specific
CXL12_RS05460	COG3730	PTS system glucitol sorbitol-specific
CXL12_RS05465	COG2951	lytic endotransglycosylase activity
CXL12_RS05475	COG1546	Belongs to the CinA family
CXL12_RS05500	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CXL12_RS05535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXL12_RS05540	COG1238	metal cluster binding
CXL12_RS05560	COG2814	Major facilitator Superfamily
CXL12_RS05565	COG1566	PFAM secretion protein HlyD family protein
CXL12_RS05570	COG1846	Transcriptional regulator
CXL12_RS05575	COG2814	Major facilitator Superfamily
CXL12_RS05625	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXL12_RS05635	COG4575	ribosome binding
CXL12_RS05665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXL12_RS05670	COG0640	Transcriptional regulator
CXL12_RS05675	COG0401	homolog of Blt101
CXL12_RS05685	COG1652	LysM domain
CXL12_RS05690	COG1802	Transcriptional regulator
CXL12_RS05695	COG1113	amino acid transport
CXL12_RS05700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXL12_RS05705	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS05710	COG0579	oxidoreductase
CXL12_RS05745	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CXL12_RS05760	COG2990	Protein conserved in bacteria
CXL12_RS05780	COG2819	hydrolase of the alpha beta superfamily
CXL12_RS05810	COG3813	Protein conserved in bacteria
CXL12_RS05820	COG2826	transposase and inactivated derivatives, IS30 family
CXL12_RS05855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXL12_RS05880	COG2867	negative regulation of translational initiation
CXL12_RS05895	COG0497	DNA recombination
CXL12_RS05920	COG4536	flavin adenine dinucleotide binding
CXL12_RS05925	COG4137	Cytochrome C assembly protein
CXL12_RS05935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXL12_RS05960	COG2199	diguanylate cyclase activity
CXL12_RS05975	COG1605	Chorismate mutase
CXL12_RS05975	COG0287	Prephenate dehydrogenase
CXL12_RS05985	COG0077	Prephenate dehydratase
CXL12_RS05985	COG1605	Chorismate mutase
CXL12_RS05995	COG4974	Belongs to the 'phage' integrase family
CXL12_RS06040	COG4695	Portal protein
CXL12_RS06135	COG5301	cellulose 1,4-beta-cellobiosidase activity
CXL12_RS06165	COG1196	nuclear chromosome segregation
CXL12_RS06175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXL12_RS06180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXL12_RS06195	COG0542	response to heat
CXL12_RS06230	COG0477	Major facilitator Superfamily
CXL12_RS06235	COG5544	Lipoprotein
CXL12_RS06240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXL12_RS06250	COG3148	PFAM DTW domain containing protein
CXL12_RS06255	COG3118	belongs to the thioredoxin family
CXL12_RS06260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXL12_RS06280	COG0583	DNA-binding transcription factor activity
CXL12_RS06285	COG0513	Belongs to the DEAD box helicase family
CXL12_RS06295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXL12_RS06320	COG3086	response to oxidative stress
CXL12_RS06370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXL12_RS06375	COG0583	DNA-binding transcription factor activity
CXL12_RS06380	COG2223	nitrite transmembrane transporter activity
CXL12_RS06385	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CXL12_RS06390	COG1737	Transcriptional regulator
CXL12_RS06400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL12_RS06400	COG1263	PTS System
CXL12_RS06405	COG0560	Phosphoserine phosphatase
CXL12_RS06430	COG2205	protein histidine kinase activity
CXL12_RS06435	COG3170	Tfp pilus assembly protein FimV
CXL12_RS06440	COG2204	response regulator
CXL12_RS06445	COG0347	Belongs to the P(II) protein family
CXL12_RS06450	COG3104	oligopeptide transport
CXL12_RS06460	COG0531	amino acid
CXL12_RS06465	COG3710	Transcriptional regulator
CXL12_RS06470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXL12_RS06470	COG1017	nitric oxide dioxygenase activity
CXL12_RS06480	COG2814	Major facilitator Superfamily
CXL12_RS06485	COG3711	transcriptional antiterminator
CXL12_RS06495	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CXL12_RS06540	COG0822	iron-sulfur transferase activity
CXL12_RS06560	COG0633	Ferredoxin
CXL12_RS06565	COG2975	iron-sulfur cluster assembly
CXL12_RS06600	COG2897	thiosulfate sulfurtransferase activity
CXL12_RS06605	COG2373	Large extracellular alpha-helical protein
CXL12_RS06610	COG4953	penicillin-binding protein 1C
CXL12_RS06615	COG0243	molybdopterin cofactor binding
CXL12_RS06620	COG0437	4 iron, 4 sulfur cluster binding
CXL12_RS06665	COG2976	Protein conserved in bacteria
CXL12_RS06680	COG1645	bacterial-type flagellum-dependent swarming motility
CXL12_RS06715	COG0517	IMP dehydrogenase activity
CXL12_RS06715	COG0516	GMP reductase activity
CXL12_RS06750	COG2200	EAL domain
CXL12_RS06765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXL12_RS06780	COG2233	PERMEase
CXL12_RS06790	COG1393	Belongs to the ArsC family
CXL12_RS06800	COG0628	permease
CXL12_RS06805	COG3835	regulator
CXL12_RS06810	COG2610	gluconate transmembrane transporter activity
CXL12_RS06815	COG1929	Belongs to the glycerate kinase type-1 family
CXL12_RS06820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CXL12_RS06825	COG2716	regulation of RNA biosynthetic process
CXL12_RS06835	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CXL12_RS06845	COG2321	neutral zinc metallopeptidase
CXL12_RS06865	COG1393	Belongs to the ArsC family
CXL12_RS06875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXL12_RS06880	COG3850	Histidine kinase
CXL12_RS06885	COG0493	'glutamate synthase
CXL12_RS06885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXL12_RS06905	COG5342	invasion associated locus B
CXL12_RS06915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXL12_RS07055	COG2837	iron assimilation
CXL12_RS07075	COG4208	sulfate ABC transporter
CXL12_RS07140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS07165	COG3530	Putative quorum-sensing-regulated virulence factor
CXL12_RS07170	COG0385	Bile acid
CXL12_RS07175	COG0583	DNA-binding transcription factor activity
CXL12_RS07185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CXL12_RS07190	COG2211	Major facilitator Superfamily
CXL12_RS07200	COG0583	DNA-binding transcription factor activity
CXL12_RS07230	COG3415	Transposase
CXL12_RS07235	COG3415	Transposase
CXL12_RS07255	COG2199	diguanylate cyclase activity
CXL12_RS07255	COG2200	EAL domain
CXL12_RS07260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXL12_RS07275	COG0667	Aldo Keto reductase
CXL12_RS07285	COG3961	Belongs to the TPP enzyme family
CXL12_RS07305	COG0436	Aminotransferase
CXL12_RS07315	COG1560	Kdo2-lipid A biosynthetic process
CXL12_RS07425	COG4712	double-strand break repair protein
CXL12_RS07580	COG0484	heat shock protein binding
CXL12_RS07590	COG3772	lysozyme
CXL12_RS07755	COG0582	viral genome integration into host DNA
CXL12_RS07765	COG2116	formate transmembrane transporter activity
CXL12_RS07785	COG3691	Protein conserved in bacteria
CXL12_RS07800	COG2062	phosphohistidine phosphatase, SixA
CXL12_RS07825	COG0730	response to heat
CXL12_RS07830	COG3101	peptidyl-lysine hydroxylation
CXL12_RS07845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXL12_RS07865	COG3423	Transcriptional regulator
CXL12_RS07890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXL12_RS07900	COG0586	Pfam SNARE associated Golgi protein
CXL12_RS07910	COG0285	dihydrofolate synthase activity
CXL12_RS07915	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CXL12_RS07920	COG1286	toxin biosynthetic process
CXL12_RS07925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CXL12_RS07930	COG3829	transcription factor binding
CXL12_RS07940	COG0531	amino acid
CXL12_RS07945	COG3457	Alanine racemase
CXL12_RS07950	COG0833	amino acid
CXL12_RS07990	COG1090	epimerase
CXL12_RS07995	COG0625	glutathione transferase activity
CXL12_RS08000	COG0625	glutathione transferase activity
CXL12_RS08005	COG0622	Phosphoesterase
CXL12_RS08015	COG1609	Transcriptional regulator
CXL12_RS08025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS08035	COG3037	sugar-specific permease SgaT UlaA
CXL12_RS08040	COG3959	Transketolase, thiamine diphosphate binding domain
CXL12_RS08045	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CXL12_RS08050	COG1288	antiporter activity
CXL12_RS08075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXL12_RS08080	COG0471	metal ion transport
CXL12_RS08080	COG0490	domain, Protein
CXL12_RS08090	COG0436	Aminotransferase
CXL12_RS08100	COG0583	DNA-binding transcription factor activity
CXL12_RS08150	COG0839	Belongs to the complex I subunit 6 family
CXL12_RS08160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXL12_RS08165	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXL12_RS08180	COG2304	oxidoreductase activity
CXL12_RS08185	COG0784	Response regulator, receiver
CXL12_RS08185	COG0835	chemotaxis
CXL12_RS08195	COG2153	protein acetylation
CXL12_RS08200	COG4575	ribosome binding
CXL12_RS08205	COG1169	isochorismate synthase
CXL12_RS08295	COG1414	Transcriptional regulator
CXL12_RS08305	COG2271	Major facilitator Superfamily
CXL12_RS08330	COG0247	lactate metabolic process
CXL12_RS08340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXL12_RS08345	COG2271	Major facilitator Superfamily
CXL12_RS08350	COG0584	glycerophosphoryl diester phosphodiesterase
CXL12_RS08355	COG0583	DNA-binding transcription factor activity
CXL12_RS08360	COG2814	Major facilitator Superfamily
CXL12_RS08365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXL12_RS08400	COG0642	Histidine kinase
CXL12_RS08400	COG2198	Histidine kinase
CXL12_RS08430	COG4615	Cyclic peptide transporter
CXL12_RS08440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXL12_RS08440	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXL12_RS08445	COG3062	negative regulation of establishment of protein localization
CXL12_RS08455	COG0437	4 iron, 4 sulfur cluster binding
CXL12_RS08460	COG0348	domain, Protein
CXL12_RS08470	COG3043	anaerobic respiration
CXL12_RS08475	COG3005	denitrification pathway
CXL12_RS08485	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXL12_RS08490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXL12_RS08495	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXL12_RS08505	COG1138	Cytochrome C-type biogenesis protein
CXL12_RS08510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL12_RS08515	COG3088	subunit of a heme lyase
CXL12_RS08515	COG4235	cytochrome complex assembly
CXL12_RS08520	COG2197	response regulator
CXL12_RS08570	COG1061	Type III restriction enzyme res subunit
CXL12_RS08580	COG2814	Major facilitator Superfamily
CXL12_RS08595	COG4172	Belongs to the ABC transporter superfamily
CXL12_RS08600	COG4239	(ABC) transporter, permease
CXL12_RS08605	COG4174	ABC transporter (Permease)
CXL12_RS08610	COG4166	transmembrane transport
CXL12_RS08615	COG2200	EAL domain
CXL12_RS08625	COG0791	NLP P60 protein
CXL12_RS08635	COG0671	phosphoesterase, PA-phosphatase related
CXL12_RS08640	COG0523	cobalamin synthesis protein
CXL12_RS08675	COG1105	Belongs to the carbohydrate kinase PfkB family
CXL12_RS08680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXL12_RS08680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXL12_RS08680	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CXL12_RS08690	COG2855	membrane
CXL12_RS08695	COG0583	DNA-binding transcription factor activity
CXL12_RS08700	COG0833	amino acid
CXL12_RS08710	COG4771	TonB-dependent receptor
CXL12_RS08715	COG2271	Major facilitator Superfamily
CXL12_RS08720	COG0560	Phosphoserine phosphatase
CXL12_RS08725	COG1760	l-serine dehydratase
CXL12_RS08750	COG2311	Membrane
CXL12_RS08780	COG0493	'glutamate synthase
CXL12_RS08790	COG2949	membrane
CXL12_RS08800	COG1346	cytolysis
CXL12_RS08815	COG2271	Major facilitator Superfamily
CXL12_RS08830	COG0625	glutathione transferase activity
CXL12_RS08835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXL12_RS08850	COG1538	Outer membrane efflux protein
CXL12_RS08855	COG1028	Short-chain dehydrogenase reductase Sdr
CXL12_RS08860	COG0586	Pfam SNARE associated Golgi protein
CXL12_RS08875	COG1686	Belongs to the peptidase S11 family
CXL12_RS08880	COG0277	FAD linked oxidase domain protein
CXL12_RS08890	COG1732	Glycine betaine
CXL12_RS08895	COG1174	glycine betaine transport
CXL12_RS08900	COG1125	glycine betaine transport
CXL12_RS08905	COG1174	glycine betaine transport
CXL12_RS08920	COG3275	phosphorelay sensor kinase activity
CXL12_RS08930	COG4807	Protein conserved in bacteria
CXL12_RS08940	COG4808	Protein conserved in bacteria
CXL12_RS08965	COG3121	Chaperone
CXL12_RS08970	COG3188	usher protein
CXL12_RS08975	COG3539	Fimbrial protein
CXL12_RS08980	COG5455	response to cobalt ion
CXL12_RS08995	COG2188	Transcriptional regulator
CXL12_RS09000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS09005	COG1397	ADP-ribosylglycohydrolase
CXL12_RS09010	COG2211	Major facilitator Superfamily
CXL12_RS09015	COG1830	Aldolase
CXL12_RS09040	COG0826	peptidase U32
CXL12_RS09095	COG1413	lyase activity
CXL12_RS09100	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXL12_RS09150	COG0745	RESPONSE REGULATOR receiver
CXL12_RS09155	COG2205	protein histidine kinase activity
CXL12_RS09185	COG0443	Heat shock 70 kDa protein
CXL12_RS09195	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CXL12_RS09200	COG3447	MASE1 domain protein
CXL12_RS09200	COG5002	protein histidine kinase activity
CXL12_RS09200	COG5001	Diguanylate cyclase
CXL12_RS09215	COG2982	Protein involved in outer membrane biogenesis
CXL12_RS09220	COG1253	flavin adenine dinucleotide binding
CXL12_RS09245	COG0463	Glycosyl transferase, family 2
CXL12_RS09250	COG1045	serine acetyltransferase
CXL12_RS09255	COG0438	transferase activity, transferring glycosyl groups
CXL12_RS09265	COG1216	Glycosyl transferase, family 2
CXL12_RS09270	COG0110	maltose O-acetyltransferase activity
CXL12_RS09275	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CXL12_RS09280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL12_RS09290	COG0297	glycogen (starch) synthase activity
CXL12_RS09305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CXL12_RS09310	COG2244	polysaccharide biosynthetic process
CXL12_RS09315	COG2327	Polysaccharide pyruvyl transferase
CXL12_RS09435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL12_RS09440	COG0583	DNA-binding transcription factor activity
CXL12_RS09450	COG0531	amino acid
CXL12_RS09455	COG2925	Exonuclease
CXL12_RS09500	COG1289	transmembrane transporter activity
CXL12_RS09535	COG4656	Part of a membrane complex involved in electron transport
CXL12_RS09540	COG1454	alcohol dehydrogenase
CXL12_RS09540	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS09545	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS09555	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CXL12_RS09570	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CXL12_RS09700	COG1122	ATPase activity
CXL12_RS09740	COG1982	Orn Lys Arg decarboxylase major
CXL12_RS09750	COG0697	spore germination
CXL12_RS09760	COG0583	DNA-binding transcription factor activity
CXL12_RS09770	COG0640	Transcriptional regulator
CXL12_RS09775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXL12_RS09790	COG0798	PFAM Bile acid sodium symporter
CXL12_RS09810	COG0534	Mate efflux family protein
CXL12_RS09840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CXL12_RS09915	COG3423	Transcriptional regulator
CXL12_RS09930	COG0582	viral genome integration into host DNA
CXL12_RS09995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXL12_RS10005	COG1418	mRNA catabolic process
CXL12_RS10010	COG0270	DNA (cytosine-5-)-methyltransferase activity
CXL12_RS10015	COG3727	T/G mismatch-specific endonuclease activity
CXL12_RS10020	COG0697	spore germination
CXL12_RS10025	COG2354	Protein conserved in bacteria
CXL12_RS10030	COG5475	Uncharacterized small protein (DUF2158)
CXL12_RS10135	COG0425	Belongs to the sulfur carrier protein TusA family
CXL12_RS10195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL12_RS10205	COG0765	amino acid transport
CXL12_RS10210	COG1126	abc transporter atp-binding protein
CXL12_RS10215	COG2197	response regulator
CXL12_RS10230	COG2197	response regulator
CXL12_RS10275	COG3318	Belongs to the UPF0149 family
CXL12_RS10275	COG3012	SEC-C Motif Domain Protein
CXL12_RS10280	COG0814	amino acid
CXL12_RS10290	COG1528	Iron-storage protein
CXL12_RS10305	COG1528	Iron-storage protein
CXL12_RS10315	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXL12_RS10410	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CXL12_RS10425	COG3102	Protein conserved in bacteria
CXL12_RS10450	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CXL12_RS10455	COG1801	Protein of unknown function DUF72
CXL12_RS10460	COG1335	isochorismatase
CXL12_RS10470	COG0494	nUDIX hydrolase
CXL12_RS10505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXL12_RS10515	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CXL12_RS10520	COG0739	heme binding
CXL12_RS10530	COG1560	Kdo2-lipid A biosynthetic process
CXL12_RS10540	COG1737	Transcriptional regulator
CXL12_RS10550	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CXL12_RS10555	COG0129	dihydroxy-acid dehydratase activity
CXL12_RS10560	COG0800	Aldolase
CXL12_RS10570	COG3141	response to X-ray
CXL12_RS10580	COG2979	Protein of unknown function (DUF533)
CXL12_RS10585	COG1770	oligopeptidase
CXL12_RS10590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXL12_RS10595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXL12_RS10605	COG2372	response to copper ion
CXL12_RS10610	COG1276	copper resistance
CXL12_RS10660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CXL12_RS10680	COG5562	phage envelope protein
CXL12_RS10720	COG3008	intermembrane lipid transfer
CXL12_RS10725	COG2995	paraquat-inducible protein a
CXL12_RS10730	COG1956	GAF domain-containing protein
CXL12_RS10750	COG2814	Major facilitator Superfamily
CXL12_RS10755	COG1414	Transcriptional regulator
CXL12_RS10785	COG0768	penicillin binding
CXL12_RS10790	COG2226	methyltransferase
CXL12_RS10810	COG3716	PTS system mannose fructose sorbose family IID component
CXL12_RS10815	COG3715	PTS system
CXL12_RS10820	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS10820	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL12_RS10830	COG1253	flavin adenine dinucleotide binding
CXL12_RS10835	COG2200	EAL domain
CXL12_RS10840	COG1760	l-serine dehydratase
CXL12_RS10860	COG0251	oxidation-reduction process
CXL12_RS10865	COG1199	ATP-dependent helicase activity
CXL12_RS10875	COG3065	identical protein binding
CXL12_RS10890	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CXL12_RS10900	COG2894	cell division
CXL12_RS10915	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXL12_RS10955	COG2719	SpoVR family
CXL12_RS10975	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXL12_RS11000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXL12_RS11010	COG1294	oxidase, subunit
CXL12_RS11015	COG1271	oxidase subunit
CXL12_RS11020	COG1773	rubredoxin
CXL12_RS11025	COG1999	signal sequence binding
CXL12_RS11030	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CXL12_RS11035	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CXL12_RS11045	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXL12_RS11065	COG0012	GTP binding
CXL12_RS11080	COG0659	secondary active sulfate transmembrane transporter activity
CXL12_RS11130	COG0387	Pfam Sodium calcium exchanger
CXL12_RS11135	COG4572	Cation transport regulator
CXL12_RS11140	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CXL12_RS11145	COG4932	domain protein
CXL12_RS11150	COG2197	response regulator
CXL12_RS11155	COG3850	Histidine kinase
CXL12_RS11165	COG2223	nitrite transmembrane transporter activity
CXL12_RS11170	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXL12_RS11175	COG1140	nitrate reductase beta subunit
CXL12_RS11180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXL12_RS11185	COG2181	nitrate reductase activity
CXL12_RS11230	COG0788	formyltetrahydrofolate deformylase activity
CXL12_RS11240	COG1752	Esterase of the alpha-beta hydrolase superfamily
CXL12_RS11245	COG0745	RESPONSE REGULATOR receiver
CXL12_RS11250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXL12_RS11265	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS11265	COG1454	alcohol dehydrogenase
CXL12_RS11270	COG2095	MarC family integral membrane protein
CXL12_RS11305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXL12_RS11320	COG2350	Protein conserved in bacteria
CXL12_RS11345	COG0727	PFAM Uncharacterised protein family (UPF0153)
CXL12_RS11350	COG3047	cAMP biosynthetic process
CXL12_RS11355	COG3546	catalase activity
CXL12_RS11360	COG3685	Protein conserved in bacteria
CXL12_RS11365	COG3685	Protein conserved in bacteria
CXL12_RS11370	COG3729	General stress protein
CXL12_RS11410	COG0009	L-threonylcarbamoyladenylate synthase
CXL12_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
CXL12_RS11430	COG0616	signal peptide processing
CXL12_RS11475	COG0671	phosphoesterase, PA-phosphatase related
CXL12_RS11485	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CXL12_RS11490	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CXL12_RS11510	COG1349	DNA-binding transcription factor activity
CXL12_RS11520	COG5001	Diguanylate cyclase
CXL12_RS11535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXL12_RS11535	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXL12_RS11590	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CXL12_RS11595	COG1842	Phage shock protein A
CXL12_RS11605	COG1983	PspC domain protein
CXL12_RS11615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXL12_RS11620	COG3106	COG3106 Predicted ATPase
CXL12_RS11640	COG4948	Mandelate Racemase Muconate Lactonizing
CXL12_RS11645	COG2866	Carboxypeptidase
CXL12_RS11650	COG4166	transmembrane transport
CXL12_RS11655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXL12_RS11675	COG0583	DNA-binding transcription factor activity
CXL12_RS11680	COG0251	oxidation-reduction process
CXL12_RS11685	COG0814	amino acid
CXL12_RS11690	COG0626	cystathionine gamma-synthase activity
CXL12_RS11700	COG0583	DNA-binding transcription factor activity
CXL12_RS11705	COG0656	L-ascorbic acid biosynthetic process
CXL12_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
CXL12_RS11715	COG1309	transcriptional regulator
CXL12_RS11750	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXL12_RS11770	COG0668	transmembrane transport
CXL12_RS11775	COG3182	Iron-regulated membrane protein
CXL12_RS11795	COG2840	Smr protein MutS2
CXL12_RS11800	COG0840	transmembrane signaling receptor activity
CXL12_RS11815	COG0513	Belongs to the DEAD box helicase family
CXL12_RS11835	COG2076	Multidrug Resistance protein
CXL12_RS11850	COG1013	pyruvate-flavodoxin oxidoreductase activity
CXL12_RS11850	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CXL12_RS11850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXL12_RS11850	COG0674	pyruvate-flavodoxin oxidoreductase activity
CXL12_RS11860	COG3042	response to heat
CXL12_RS11865	COG3187	Heat shock protein
CXL12_RS11870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXL12_RS11875	COG2911	Protein conserved in bacteria
CXL12_RS11885	COG3784	Protein of unknown function (DUF1318)
CXL12_RS11900	COG1643	Atp-dependent helicase
CXL12_RS11905	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CXL12_RS11910	COG3038	cytochrome b561
CXL12_RS11915	COG0500	methyltransferase
CXL12_RS11925	COG0765	amino acid transport
CXL12_RS11935	COG0765	amino acid transport
CXL12_RS11940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL12_RS11980	COG0840	transmembrane signaling receptor activity
CXL12_RS11985	COG0583	DNA-binding transcription factor activity
CXL12_RS11990	COG5383	Protein conserved in bacteria
CXL12_RS11995	COG2272	Belongs to the type-B carboxylesterase lipase family
CXL12_RS12010	COG1304	FMN binding
CXL12_RS12020	COG1349	DNA-binding transcription factor activity
CXL12_RS12025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXL12_RS12030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS12035	COG0434	BtpA family
CXL12_RS12040	COG3775	system Galactitol-specific IIC component
CXL12_RS12045	COG3414	Phosphotransferase system galactitol-specific IIB component
CXL12_RS12055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXL12_RS12060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXL12_RS12065	COG1275	C4-dicarboxylate transporter malic acid transport protein
CXL12_RS12070	COG0500	methyltransferase
CXL12_RS12080	COG3135	benzoate transporter
CXL12_RS12085	COG1396	sequence-specific DNA binding
CXL12_RS12090	COG0826	peptidase U32
CXL12_RS12115	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CXL12_RS12120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXL12_RS12160	COG3238	Protein conserved in bacteria
CXL12_RS12170	COG2130	NADP-dependent
CXL12_RS12175	COG1802	Transcriptional regulator
CXL12_RS12180	COG4772	TonB-dependent receptor
CXL12_RS12220	COG2181	nitrate reductase activity
CXL12_RS12225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXL12_RS12230	COG1140	nitrate reductase beta subunit
CXL12_RS12235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXL12_RS12275	COG3383	formate dehydrogenase (NAD+) activity
CXL12_RS12275	COG0243	molybdopterin cofactor binding
CXL12_RS12280	COG0243	molybdopterin cofactor binding
CXL12_RS12280	COG3383	formate dehydrogenase (NAD+) activity
CXL12_RS12285	COG0437	4 iron, 4 sulfur cluster binding
CXL12_RS12290	COG2864	formate dehydrogenase
CXL12_RS12295	COG1064	alcohol dehydrogenase
CXL12_RS12315	COG1764	response to oxidative stress
CXL12_RS12330	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CXL12_RS12345	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXL12_RS12350	COG1757	Na H antiporter
CXL12_RS12355	COG1609	Transcriptional regulator
CXL12_RS12415	COG0251	oxidation-reduction process
CXL12_RS12420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CXL12_RS12445	COG2271	Major facilitator Superfamily
CXL12_RS12450	COG1063	alcohol dehydrogenase
CXL12_RS12455	COG2186	Transcriptional regulator
CXL12_RS12465	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CXL12_RS12470	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CXL12_RS12495	COG1773	rubredoxin
CXL12_RS12520	COG3781	membrane
CXL12_RS12535	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS12540	COG0583	DNA-binding transcription factor activity
CXL12_RS12580	COG2814	Major facilitator Superfamily
CXL12_RS12595	COG3111	PFAM Bacterial OB fold (BOF) protein
CXL12_RS12600	COG1546	Belongs to the CinA family
CXL12_RS12605	COG3729	General stress protein
CXL12_RS12620	COG4221	oxidoreductase activity
CXL12_RS12625	COG1802	Transcriptional regulator
CXL12_RS12635	COG0246	Mannitol dehydrogenase
CXL12_RS12640	COG0477	Major facilitator Superfamily
CXL12_RS12645	COG1063	alcohol dehydrogenase
CXL12_RS12665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXL12_RS12680	COG0243	molybdopterin cofactor binding
CXL12_RS12685	COG0243	molybdopterin cofactor binding
CXL12_RS12690	COG0437	4 iron, 4 sulfur cluster binding
CXL12_RS12695	COG3302	dmso reductase anchor subunit
CXL12_RS12735	COG1940	carbohydrate kinase activity
CXL12_RS12745	COG0583	DNA-binding transcription factor activity
CXL12_RS12750	COG2814	Major facilitator Superfamily
CXL12_RS12760	COG3591	Belongs to the peptidase S1B family
CXL12_RS12780	COG0628	permease
CXL12_RS12785	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CXL12_RS12790	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CXL12_RS12800	COG0531	amino acid
CXL12_RS12805	COG3136	membrane protein required for alginate biosynthesis
CXL12_RS12810	COG0745	RESPONSE REGULATOR receiver
CXL12_RS12820	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXL12_RS12825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CXL12_RS12830	COG2205	protein histidine kinase activity
CXL12_RS12855	COG5339	Protein conserved in bacteria
CXL12_RS12865	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXL12_RS12875	COG0673	inositol 2-dehydrogenase activity
CXL12_RS12925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CXL12_RS12935	COG0625	glutathione transferase activity
CXL12_RS12955	COG3895	Periplasmic Protein
CXL12_RS12980	COG1566	PFAM secretion protein HlyD family protein
CXL12_RS12995	COG4989	oxidoreductase activity
CXL12_RS13000	COG3313	Fe-S protein
CXL12_RS13005	COG1309	transcriptional regulator
CXL12_RS13010	COG1902	pentaerythritol trinitrate reductase activity
CXL12_RS13030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CXL12_RS13035	COG0791	NLP P60 protein
CXL12_RS13060	COG0583	DNA-binding transcription factor activity
CXL12_RS13065	COG2814	Major facilitator Superfamily
CXL12_RS13070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CXL12_RS13075	COG0307	riboflavin synthase, alpha
CXL12_RS13255	COG0789	Transcriptional regulator
CXL12_RS13260	COG3272	Protein of unknown function (DUF1722)
CXL12_RS13295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS13305	COG2267	carboxylic ester hydrolase activity
CXL12_RS13310	COG0531	amino acid
CXL12_RS13345	COG1376	ErfK ybiS ycfS ynhG family protein
CXL12_RS13360	COG0719	Fe-S assembly protein
CXL12_RS13365	COG0396	ATPase activity
CXL12_RS13370	COG0719	Fe-S assembly protein
CXL12_RS13375	COG0316	Belongs to the HesB IscA family
CXL12_RS13380	COG1823	symporter activity
CXL12_RS13390	COG2050	protein possibly involved in aromatic compounds catabolism
CXL12_RS13395	COG0277	FAD linked oxidase domain protein
CXL12_RS13395	COG0247	lactate metabolic process
CXL12_RS13400	COG0628	permease
CXL12_RS13415	COG0738	Major facilitator superfamily
CXL12_RS13420	COG2271	Major facilitator Superfamily
CXL12_RS13435	COG4670	ketone body catabolic process
CXL12_RS13440	COG1960	acyl-CoA dehydrogenase activity
CXL12_RS13445	COG2207	Transcriptional regulator
CXL12_RS13445	COG1917	Cupin 2, conserved barrel domain protein
CXL12_RS13450	COG2086	electron transfer activity
CXL12_RS13455	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CXL12_RS13460	COG0644	oxidoreductase
CXL12_RS13465	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CXL12_RS13470	COG0318	PFAM AMP-dependent synthetase and ligase
CXL12_RS13475	COG0574	Belongs to the PEP-utilizing enzyme family
CXL12_RS13475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXL12_RS13490	COG4256	Hemin uptake protein
CXL12_RS13505	COG0791	NLP P60 protein
CXL12_RS13515	COG0386	Belongs to the glutathione peroxidase family
CXL12_RS13580	COG3137	Salt-induced outer membrane protein
CXL12_RS13585	COG1105	Belongs to the carbohydrate kinase PfkB family
CXL12_RS13595	COG3001	Fructosamine kinase
CXL12_RS13605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXL12_RS13610	COG1988	membrane-bound metal-dependent
CXL12_RS13615	COG1823	symporter activity
CXL12_RS13625	COG0753	catalase activity
CXL12_RS13635	COG1486	melibiose metabolic process
CXL12_RS13640	COG2169	Transcriptional regulator
CXL12_RS13640	COG1917	Cupin 2, conserved barrel domain protein
CXL12_RS13645	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXL12_RS13650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXL12_RS13655	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXL12_RS13665	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXL12_RS13675	COG0322	excinuclease ABC activity
CXL12_RS13680	COG3678	ATP-independent chaperone mediated protein folding
CXL12_RS13695	COG3724	N-succinylarginine dihydrolase activity
CXL12_RS13725	COG0494	nUDIX hydrolase
CXL12_RS13750	COG0778	Nitroreductase
CXL12_RS13755	COG0616	signal peptide processing
CXL12_RS13760	COG0252	asparaginase activity
CXL12_RS13765	COG1335	isochorismatase
CXL12_RS13770	COG3139	Protein of unknown function (DUF1315)
CXL12_RS13795	COG0656	L-ascorbic acid biosynthetic process
CXL12_RS13800	COG0641	radical SAM
CXL12_RS13805	COG3713	MltA-interacting MipA family protein
CXL12_RS13810	COG2766	serine protein kinase
CXL12_RS13825	COG2199	diguanylate cyclase activity
CXL12_RS13830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXL12_RS13845	COG2207	Transcriptional regulator
CXL12_RS13850	COG2807	transmembrane transport
CXL12_RS13855	COG3189	MarR family transcriptional regulator
CXL12_RS13865	COG3042	response to heat
CXL12_RS13875	COG2261	transglycosylase associated protein
CXL12_RS13895	COG3615	Tellurite resistance protein tehB
CXL12_RS13910	COG1605	Chorismate mutase
CXL12_RS13925	COG0789	Transcriptional regulator
CXL12_RS13940	COG3443	Belongs to the bacterial solute-binding protein 9 family
CXL12_RS13955	COG0668	transmembrane transport
CXL12_RS13960	COG1124	(ABC) transporter
CXL12_RS13975	COG0601	transmembrane transport
CXL12_RS13990	COG3038	cytochrome b561
CXL12_RS14000	COG0071	Belongs to the small heat shock protein (HSP20) family
CXL12_RS14100	COG0538	isocitrate dehydrogenase activity
CXL12_RS14130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXL12_RS14145	COG2850	peptidyl-arginine hydroxylation
CXL12_RS14175	COG1177	transmembrane transport
CXL12_RS14195	COG4591	ABC-type transport system involved in lipoprotein release permease component
CXL12_RS14200	COG1136	(ABC) transporter
CXL12_RS14205	COG4591	ABC-type transport system involved in lipoprotein release permease component
CXL12_RS14210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CXL12_RS14215	COG1376	ErfK ybiS ycfS ynhG family protein
CXL12_RS14215	COG1388	LysM domain
CXL12_RS14225	COG1309	transcriptional regulator
CXL12_RS14230	COG3134	Outer membrane lipoprotein
CXL12_RS14235	COG1252	NADH dehydrogenase
CXL12_RS14260	COG5633	Lipoprotein
CXL12_RS14265	COG0537	adenosine 5'-monophosphoramidase activity
CXL12_RS14270	COG4773	Receptor
CXL12_RS14280	COG0084	hydrolase, TatD family'
CXL12_RS14285	COG0470	DNA polymerase III
CXL12_RS14295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXL12_RS14300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXL12_RS14305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXL12_RS14370	COG1530	ribonuclease E activity
CXL12_RS14470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXL12_RS14480	COG2999	glutathione oxidoreductase activity
CXL12_RS14520	COG3038	cytochrome b561
CXL12_RS14535	COG1560	Kdo2-lipid A biosynthetic process
CXL12_RS14555	COG5645	(Lipo)protein
CXL12_RS14560	COG2943	transferase activity, transferring hexosyl groups
CXL12_RS14575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXL12_RS14635	COG3381	protein complex oligomerization
CXL12_RS14695	COG1702	phosphate starvation-inducible protein PhoH
CXL12_RS14725	COG1309	transcriptional regulator
CXL12_RS14730	COG3729	General stress protein
CXL12_RS14750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL12_RS14755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXL12_RS14755	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CXL12_RS14760	COG4232	protein-disulfide reductase activity
CXL12_RS14815	COG3971	2-oxopent-4-enoate hydratase activity
CXL12_RS14830	COG3384	dioxygenase
CXL12_RS14835	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS14845	COG1846	Transcriptional regulator
CXL12_RS14850	COG2368	4-hydroxyphenylacetate
CXL12_RS14875	COG0745	RESPONSE REGULATOR receiver
CXL12_RS14880	COG2205	protein histidine kinase activity
CXL12_RS14925	COG0670	Belongs to the BI1 family
CXL12_RS14945	COG1881	PFAM PEBP family protein
CXL12_RS14960	COG1832	CoA-binding protein
CXL12_RS14975	COG0210	DNA helicase
CXL12_RS14980	COG3304	Inner membrane component domain
CXL12_RS14985	COG1289	transmembrane transporter activity
CXL12_RS14990	COG3070	regulator of competence-specific genes
CXL12_RS15010	COG1067	ATP-dependent peptidase activity
CXL12_RS15020	COG3130	regulation of translation
CXL12_RS15025	COG3009	Protein conserved in bacteria
CXL12_RS15030	COG3008	intermembrane lipid transfer
CXL12_RS15030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXL12_RS15035	COG2995	paraquat-inducible protein a
CXL12_RS15040	COG0488	(ABC) transporter
CXL12_RS15050	COG3217	Mosc domain protein beta barrel domain protein
CXL12_RS15050	COG0633	Ferredoxin
CXL12_RS15065	COG0308	aminopeptidase N
CXL12_RS15075	COG1115	amino acid carrier protein
CXL12_RS15090	COG1522	sequence-specific DNA binding
CXL12_RS15095	COG0017	Asparaginyl-tRNA synthetase
CXL12_RS15100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXL12_RS15110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXL12_RS15115	COG3108	Peptidase M15
CXL12_RS15125	COG2989	Protein conserved in bacteria
CXL12_RS15135	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CXL12_RS15145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CXL12_RS15150	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CXL12_RS15155	COG3173	Aminoglycoside phosphotransferase
CXL12_RS15170	COG3214	Protein conserved in bacteria
CXL12_RS15185	COG0658	competence protein
CXL12_RS15185	COG2333	competence protein COMEC
CXL12_RS15195	COG0539	negative regulation of cytoplasmic translation
CXL12_RS15205	COG0501	Belongs to the peptidase M48B family
CXL12_RS15220	COG2323	membrane
CXL12_RS15225	COG1944	ATP diphosphatase activity
CXL12_RS15230	COG2116	formate transmembrane transporter activity
CXL12_RS15235	COG1882	Formate acetyltransferase
CXL12_RS15245	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXL12_RS15250	COG0531	amino acid
CXL12_RS15260	COG3302	dmso reductase anchor subunit
CXL12_RS15265	COG0437	4 iron, 4 sulfur cluster binding
CXL12_RS15270	COG0243	molybdopterin cofactor binding
CXL12_RS15280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXL12_RS15305	COG0492	ferredoxin-NADP+ reductase activity
CXL12_RS15310	COG4988	ABC transporter
CXL12_RS15315	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CXL12_RS15335	COG0583	DNA-binding transcription factor activity
CXL12_RS15345	COG1335	isochorismatase
CXL12_RS15360	COG0542	response to heat
CXL12_RS15370	COG1278	Cold shock
CXL12_RS15380	COG1136	(ABC) transporter
CXL12_RS15380	COG0577	efflux transmembrane transporter activity
CXL12_RS15385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXL12_RS15390	COG2990	Protein conserved in bacteria
CXL12_RS15395	COG3593	DNA synthesis involved in DNA repair
CXL12_RS15405	COG2431	L-lysine efflux transmembrane transporter activity
CXL12_RS15415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXL12_RS15420	COG0028	Belongs to the TPP enzyme family
CXL12_RS15425	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CXL12_RS15430	COG0702	epimerase
CXL12_RS15435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL12_RS15440	COG3023	N-Acetylmuramoyl-L-alanine amidase
CXL12_RS15455	COG1126	abc transporter atp-binding protein
CXL12_RS15460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL12_RS15465	COG4215	(ABC) transporter
CXL12_RS15470	COG4160	amino acid transport
CXL12_RS15475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL12_RS15510	COG1177	transmembrane transport
CXL12_RS15515	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXL12_RS15520	COG3842	ATPase activity
CXL12_RS15525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXL12_RS15575	COG3226	Transcriptional regulator
CXL12_RS15580	COG0738	Major facilitator superfamily
CXL12_RS15585	COG0561	phosphatase activity
CXL12_RS15590	COG2814	Major facilitator Superfamily
CXL12_RS15595	COG0671	phosphoesterase, PA-phosphatase related
CXL12_RS15600	COG1349	DNA-binding transcription factor activity
CXL12_RS15605	COG1686	Belongs to the peptidase S11 family
CXL12_RS15610	COG0625	glutathione transferase activity
CXL12_RS15615	COG2133	pyrroloquinoline quinone binding
CXL12_RS15665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXL12_RS15670	COG1882	Formate acetyltransferase
CXL12_RS15675	COG0561	phosphatase activity
CXL12_RS15705	COG0488	(ABC) transporter
CXL12_RS15710	COG1376	ErfK ybiS ycfS ynhG family protein
CXL12_RS15715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXL12_RS15730	COG2194	sulfuric ester hydrolase activity
CXL12_RS15735	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CXL12_RS15755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL12_RS15760	COG0765	amino acid transport
CXL12_RS15765	COG1126	abc transporter atp-binding protein
CXL12_RS15770	COG0668	transmembrane transport
CXL12_RS15780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXL12_RS15790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXL12_RS15800	COG0513	Belongs to the DEAD box helicase family
CXL12_RS15805	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS15805	COG1454	alcohol dehydrogenase
CXL12_RS15810	COG3958	Transketolase
CXL12_RS15815	COG3959	Transketolase, thiamine diphosphate binding domain
CXL12_RS15820	COG1028	Short-chain dehydrogenase reductase Sdr
CXL12_RS15825	COG2271	Major facilitator Superfamily
CXL12_RS15830	COG0583	DNA-binding transcription factor activity
CXL12_RS15835	COG1309	transcriptional regulator
CXL12_RS15845	COG1131	(ABC) transporter
CXL12_RS15850	COG0842	Transport permease protein
CXL12_RS15855	COG0842	Transport permease protein
CXL12_RS15865	COG3568	Endonuclease Exonuclease Phosphatase
CXL12_RS15870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXL12_RS15875	COG0392	lysyltransferase activity
CXL12_RS15900	COG0670	Belongs to the BI1 family
CXL12_RS15910	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CXL12_RS15920	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXL12_RS15975	COG1881	PFAM PEBP family protein
CXL12_RS16005	COG4677	pectinesterase activity
CXL12_RS16015	COG0561	phosphatase activity
CXL12_RS16025	COG4149	molybdate abc transporter
CXL12_RS16030	COG0725	ABC transporter, periplasmic molybdate-binding protein
CXL12_RS16040	COG2005	Transcriptional regulator
CXL12_RS16040	COG3585	molybdate ion transport
CXL12_RS16045	COG1119	ATPase activity
CXL12_RS16070	COG2017	converts alpha-aldose to the beta-anomer
CXL12_RS16085	COG1120	ATPase activity
CXL12_RS16090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL12_RS16105	COG0511	ligase activity, forming carbon-carbon bonds
CXL12_RS16105	COG5016	pyruvate
CXL12_RS16115	COG0490	domain, Protein
CXL12_RS16115	COG0471	metal ion transport
CXL12_RS16120	COG0583	DNA-binding transcription factor activity
CXL12_RS16125	COG0583	DNA-binding transcription factor activity
CXL12_RS16135	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXL12_RS16135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXL12_RS16140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXL12_RS16150	COG1230	cation diffusion facilitator family transporter
CXL12_RS16190	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CXL12_RS16195	COG2885	chlorophyll binding
CXL12_RS16205	COG3064	Membrane
CXL12_RS16210	COG0848	biopolymer transport protein
CXL12_RS16215	COG0811	peptide transport
CXL12_RS16220	COG0824	Thioesterase
CXL12_RS16225	COG3790	cyd operon protein YbgE
CXL12_RS16235	COG4890	Cyd operon protein YbgT
CXL12_RS16240	COG1294	oxidase, subunit
CXL12_RS16245	COG1271	oxidase subunit
CXL12_RS16260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXL12_RS16270	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXL12_RS16275	COG0567	Dehydrogenase, E1 component
CXL12_RS16290	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CXL12_RS16315	COG3180	Ammonia monooxygenase
CXL12_RS16330	COG1984	allophanate hydrolase subunit 2
CXL12_RS16335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CXL12_RS16385	COG2205	protein histidine kinase activity
CXL12_RS16390	COG0745	RESPONSE REGULATOR receiver
CXL12_RS16400	COG1982	Orn Lys Arg decarboxylase major
CXL12_RS16405	COG0531	amino acid
CXL12_RS16415	COG0033	Phosphoglucomutase
CXL12_RS16425	COG0596	Alpha beta hydrolase
CXL12_RS16440	COG0735	belongs to the Fur family
CXL12_RS16445	COG0583	DNA-binding transcription factor activity
CXL12_RS16450	COG1053	succinate dehydrogenase
CXL12_RS16495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXL12_RS16500	COG1846	Transcriptional regulator
CXL12_RS16500	COG1940	carbohydrate kinase activity
CXL12_RS16505	COG0647	UMP catabolic process
CXL12_RS16510	COG0367	asparagine synthase
CXL12_RS16555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXL12_RS16565	COG1702	phosphate starvation-inducible protein PhoH
CXL12_RS16590	COG0765	amino acid transport
CXL12_RS16595	COG0765	amino acid transport
CXL12_RS16600	COG1126	abc transporter atp-binding protein
CXL12_RS16615	COG0443	Heat shock 70 kDa protein
CXL12_RS16620	COG2214	Heat shock protein DnaJ domain protein
CXL12_RS16630	COG2214	Heat shock protein DnaJ domain protein
CXL12_RS16645	COG2888	peptidyl-tyrosine sulfation
CXL12_RS16650	COG3829	transcription factor binding
CXL12_RS16650	COG3290	protein histidine kinase activity
CXL12_RS16680	COG1466	dna polymerase III delta subunit
CXL12_RS16690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CXL12_RS16700	COG0799	negative regulation of ribosome biogenesis
CXL12_RS16710	COG0768	penicillin binding
CXL12_RS16715	COG0772	Belongs to the SEDS family
CXL12_RS16720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXL12_RS16725	COG1686	Belongs to the peptidase S11 family
CXL12_RS16740	COG0583	DNA-binding transcription factor activity
CXL12_RS16755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXL12_RS16775	COG3069	C4-dicarboxylate transmembrane transporter activity
CXL12_RS16780	COG4565	transcriptional regulatory protein
CXL12_RS16785	COG3290	protein histidine kinase activity
CXL12_RS16790	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CXL12_RS16800	COG2301	Belongs to the HpcH HpaI aldolase family
CXL12_RS16805	COG3051	citrate lyase alpha subunit
CXL12_RS16820	COG0471	metal ion transport
CXL12_RS16825	COG3719	Belongs to the RNase T2 family
CXL12_RS16835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXL12_RS16840	COG1063	alcohol dehydrogenase
CXL12_RS16860	COG0243	molybdopterin cofactor binding
CXL12_RS16880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXL12_RS16890	COG0583	DNA-binding transcription factor activity
CXL12_RS16895	COG3969	phosphoadenosine phosphosulfate
CXL12_RS16900	COG1475	DNA binding
CXL12_RS16905	COG0436	Aminotransferase
CXL12_RS16910	COG0371	Dehydrogenase
CXL12_RS16915	COG2879	small protein
CXL12_RS16920	COG1966	Carbon starvation protein
CXL12_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
CXL12_RS16935	COG1535	isochorismatase
CXL12_RS16935	COG3433	isochorismatase activity
CXL12_RS16940	COG1021	2,3-dihydroxybenzoate-AMP ligase
CXL12_RS16945	COG1169	isochorismate synthase
CXL12_RS16950	COG4592	Periplasmic binding protein
CXL12_RS16960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL12_RS16965	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL12_RS16970	COG1120	ATPase activity
CXL12_RS16975	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CXL12_RS16980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL12_RS16980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CXL12_RS16985	COG3251	PFAM MbtH domain protein
CXL12_RS16990	COG2382	esterase
CXL12_RS16995	COG4771	TonB-dependent receptor
CXL12_RS17000	COG2977	Belongs to the P-Pant transferase superfamily
CXL12_RS17025	COG2315	Protein conserved in bacteria
CXL12_RS17050	COG3716	PTS system mannose fructose sorbose family IID component
CXL12_RS17060	COG2222	sugar isomerase
CXL12_RS17065	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CXL12_RS17065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CXL12_RS17080	COG0668	transmembrane transport
CXL12_RS17085	COG1113	amino acid transport
CXL12_RS17095	COG3059	membrane
CXL12_RS17105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXL12_RS17110	COG2207	Transcriptional regulator
CXL12_RS17130	COG2246	polysaccharide biosynthetic process
CXL12_RS17135	COG0463	Glycosyl transferase, family 2
CXL12_RS17160	COG0463	Glycosyl transferase, family 2
CXL12_RS17165	COG2246	polysaccharide biosynthetic process
CXL12_RS17180	COG0582	viral genome integration into host DNA
CXL12_RS17255	COG2501	S4 domain
CXL12_RS17260	COG1988	membrane-bound metal-dependent
CXL12_RS17280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXL12_RS17295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXL12_RS17300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CXL12_RS17305	COG0549	Belongs to the carbamate kinase family
CXL12_RS17315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXL12_RS17320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXL12_RS17325	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXL12_RS17330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXL12_RS17335	COG3257	ureidoglycine aminohydrolase activity
CXL12_RS17340	COG1929	Belongs to the glycerate kinase type-1 family
CXL12_RS17345	COG2233	PERMEase
CXL12_RS17355	COG1953	Uracil, thiamine, allantoin
CXL12_RS17365	COG2084	Dehydrogenase
CXL12_RS17370	COG3622	Belongs to the hyi family
CXL12_RS17375	COG3960	tartronate-semialdehyde synthase activity
CXL12_RS17410	COG1464	Belongs to the NlpA lipoprotein family
CXL12_RS17420	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CXL12_RS17425	COG4181	ATPase activity
CXL12_RS17430	COG2755	lipolytic protein G-D-S-L family
CXL12_RS17435	COG0300	oxidoreductase activity
CXL12_RS17440	COG3118	belongs to the thioredoxin family
CXL12_RS17445	COG0390	transport system, permease component
CXL12_RS17450	COG4619	ABC transporter
CXL12_RS17455	COG0330	HflC and HflK could
CXL12_RS17460	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXL12_RS17470	COG2217	Heavy metal translocating P-type atpase
CXL12_RS17480	COG3735	TraB family
CXL12_RS17495	COG2223	nitrite transmembrane transporter activity
CXL12_RS17500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXL12_RS17500	COG4651	solute:proton antiporter activity
CXL12_RS17505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS17560	COG2832	Protein of unknown function (DUF454)
CXL12_RS17565	COG3923	Primosomal replication protein n
CXL12_RS17575	COG5464	transposase or invertase
CXL12_RS17580	COG3264	Mechanosensitive ion channel
CXL12_RS17580	COG1196	nuclear chromosome segregation
CXL12_RS17585	COG1309	transcriptional regulator
CXL12_RS17590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXL12_RS17595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXL12_RS17610	COG0110	maltose O-acetyltransferase activity
CXL12_RS17630	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CXL12_RS17640	COG3695	enzyme binding
CXL12_RS17645	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CXL12_RS17650	COG1946	Acyl-CoA thioesterase
CXL12_RS17655	COG0004	ammonium transporteR
CXL12_RS17660	COG0347	Belongs to the P(II) protein family
CXL12_RS17665	COG1132	(ABC) transporter
CXL12_RS17670	COG1132	(ABC) transporter
CXL12_RS17675	COG1522	sequence-specific DNA binding
CXL12_RS17690	COG4533	DNA binding
CXL12_RS17700	COG0824	Thioesterase
CXL12_RS17705	COG1555	photosystem II stabilization
CXL12_RS17710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXL12_RS17720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CXL12_RS17745	COG0271	Belongs to the BolA IbaG family
CXL12_RS17750	COG3056	Lipoprotein
CXL12_RS17755	COG2223	nitrite transmembrane transporter activity
CXL12_RS17760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CXL12_RS17765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXL12_RS17770	COG1845	cytochrome c oxidase, subunit III
CXL12_RS17775	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CXL12_RS17795	COG2814	Major facilitator Superfamily
CXL12_RS17825	COG2188	Transcriptional regulator
CXL12_RS17860	COG0142	geranyltranstransferase activity
CXL12_RS17870	COG0667	Aldo Keto reductase
CXL12_RS17875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXL12_RS17880	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CXL12_RS17895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXL12_RS17895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXL12_RS17905	COG4238	major outer membrane lipoprotein
CXL12_RS17930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXL12_RS17940	COG1862	Preprotein translocase
CXL12_RS17965	COG0450	alkyl hydroperoxide reductase
CXL12_RS17975	COG0366	Alpha amylase catalytic
CXL12_RS17990	COG5002	protein histidine kinase activity
CXL12_RS18000	COG0420	3'-5' exonuclease activity
CXL12_RS18005	COG0419	ATPase involved in DNA repair
CXL12_RS18010	COG2814	Major facilitator Superfamily
CXL12_RS18015	COG1940	carbohydrate kinase activity
CXL12_RS18030	COG4126	flavin adenine dinucleotide binding
CXL12_RS18050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXL12_RS18055	COG3706	GGDEF domain
CXL12_RS18100	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CXL12_RS18110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXL12_RS18125	COG0113	porphobilinogen synthase activity
CXL12_RS18160	COG1280	lysine exporter protein (LysE YggA)
CXL12_RS18180	COG1294	oxidase, subunit
CXL12_RS18185	COG1271	oxidase subunit
CXL12_RS18205	COG2814	Major facilitator Superfamily
CXL12_RS18215	COG0789	Transcriptional regulator
CXL12_RS18220	COG2217	Heavy metal translocating P-type atpase
CXL12_RS18225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXL12_RS18270	COG2200	EAL domain
CXL12_RS18295	COG3539	Fimbrial protein
CXL12_RS18300	COG3121	Chaperone
CXL12_RS18305	COG3188	usher protein
CXL12_RS18360	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXL12_RS18365	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXL12_RS18370	COG1690	Belongs to the RtcB family
CXL12_RS18380	COG3034	peptidoglycan biosynthetic process
CXL12_RS18385	COG0121	glutamine amidotransferase
CXL12_RS18400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXL12_RS18515	COG3209	COG3209 Rhs family protein
CXL12_RS18555	COG3209	COG3209 Rhs family protein
CXL12_RS18635	COG3047	cAMP biosynthetic process
CXL12_RS18635	COG2885	chlorophyll binding
CXL12_RS18750	COG2226	methyltransferase
CXL12_RS18760	COG0741	lytic transglycosylase activity
CXL12_RS18760	COG1388	LysM domain
CXL12_RS18765	COG2226	methyltransferase
CXL12_RS18775	COG2814	Major facilitator Superfamily
CXL12_RS18780	COG0583	DNA-binding transcription factor activity
CXL12_RS18785	COG0656	L-ascorbic acid biosynthetic process
CXL12_RS18820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXL12_RS18845	COG1720	tRNA m6t6A37 methyltransferase activity
CXL12_RS18855	COG3015	lipoprotein NlpE involved in copper resistance
CXL12_RS18860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXL12_RS18875	COG4568	rho-dependent transcription termination
CXL12_RS18885	COG0346	lactoylglutathione lyase activity
CXL12_RS18890	COG1982	Orn Lys Arg decarboxylase major
CXL12_RS18950	COG0575	Belongs to the CDS family
CXL12_RS19015	COG0477	Major facilitator Superfamily
CXL12_RS19025	COG3835	regulator
CXL12_RS19050	COG2860	membrane
CXL12_RS19080	COG3539	Fimbrial protein
CXL12_RS19085	COG3539	Fimbrial protein
CXL12_RS19090	COG3121	Chaperone
CXL12_RS19095	COG3188	usher protein
CXL12_RS19115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXL12_RS19120	COG1120	ATPase activity
CXL12_RS19125	COG4774	siderophore transport
CXL12_RS19130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXL12_RS19135	COG1643	Atp-dependent helicase
CXL12_RS19140	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CXL12_RS19160	COG0617	tRNA 3'-terminal CCA addition
CXL12_RS19165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CXL12_RS19190	COG3121	Chaperone
CXL12_RS19195	COG3188	usher protein
CXL12_RS19200	COG3539	Fimbrial protein
CXL12_RS19220	COG0726	polysaccharide deacetylase
CXL12_RS19225	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS19245	COG3539	Fimbrial protein
CXL12_RS19250	COG0842	Transport permease protein
CXL12_RS19255	COG1131	(ABC) transporter
CXL12_RS19260	COG0288	reversible hydration of carbon dioxide
CXL12_RS19270	COG4993	Dehydrogenase
CXL12_RS19275	COG2132	Multicopper oxidase
CXL12_RS19295	COG1349	DNA-binding transcription factor activity
CXL12_RS19340	COG3064	Membrane
CXL12_RS19355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXL12_RS19360	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXL12_RS19365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CXL12_RS19380	COG2211	Major facilitator Superfamily
CXL12_RS19385	COG3940	Belongs to the glycosyl hydrolase 43 family
CXL12_RS19390	COG3725	Membrane protein required for beta-lactamase induction
CXL12_RS19410	COG4969	Belongs to the N-Me-Phe pilin family
CXL12_RS19415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXL12_RS19420	COG1459	type II secretion system
CXL12_RS19450	COG0494	nUDIX hydrolase
CXL12_RS19470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXL12_RS19475	COG0849	cell division
CXL12_RS19500	COG0772	Belongs to the SEDS family
CXL12_RS19515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CXL12_RS19520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXL12_RS19525	COG0768	penicillin binding
CXL12_RS19615	COG0586	Pfam SNARE associated Golgi protein
CXL12_RS19655	COG0417	DNA replication proofreading
CXL12_RS19690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CXL12_RS19740	COG3119	arylsulfatase activity
CXL12_RS19765	COG2271	Major facilitator Superfamily
CXL12_RS19775	COG0644	oxidoreductase
CXL12_RS19805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXL12_RS19930	COG1047	Peptidyl-prolyl cis-trans
CXL12_RS19945	COG0196	riboflavin kinase activity
CXL12_RS19970	COG0583	DNA-binding transcription factor activity
CXL12_RS19995	COG0641	radical SAM
CXL12_RS20000	COG3119	arylsulfatase activity
CXL12_RS20035	COG3121	Chaperone
CXL12_RS20040	COG3539	Fimbrial protein
CXL12_RS20055	COG3188	usher protein
CXL12_RS20120	COG4735	regulation of single-species biofilm formation
CXL12_RS20125	COG1584	GPR1 FUN34 yaaH family protein
CXL12_RS20130	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXL12_RS20140	COG1115	amino acid carrier protein
CXL12_RS20150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CXL12_RS20160	COG0460	homoserine dehydrogenase
CXL12_RS20160	COG0527	aspartate kinase activity
CXL12_RS20170	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CXL12_RS20180	COG0745	RESPONSE REGULATOR receiver
CXL12_RS20200	COG3121	Chaperone
CXL12_RS20220	COG4452	Inner membrane protein CreD
CXL12_RS20225	COG2205	protein histidine kinase activity
CXL12_RS20230	COG0745	RESPONSE REGULATOR receiver
CXL12_RS20235	COG3045	CreA protein
CXL12_RS20240	COG3708	Transcriptional regulator
CXL12_RS20240	COG2207	Transcriptional regulator
CXL12_RS20275	COG0488	(ABC) transporter
CXL12_RS20290	COG0560	Phosphoserine phosphatase
CXL12_RS20300	COG3726	membrane protein affecting hemolysin expression
CXL12_RS20315	COG3539	Fimbrial protein
CXL12_RS20320	COG3121	Chaperone
CXL12_RS20325	COG3188	usher protein
CXL12_RS20355	COG1328	CTP reductase activity
CXL12_RS20360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CXL12_RS20365	COG0084	hydrolase, TatD family'
CXL12_RS20370	COG4667	esterase of the alpha-beta hydrolase superfamily
CXL12_RS20380	COG2823	Periplasmic or secreted lipoprotein
CXL12_RS20390	COG1011	Hydrolase
CXL12_RS20400	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CXL12_RS20430	COG3706	GGDEF domain
CXL12_RS20435	COG4114	ferric iron reductase
CXL12_RS20440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXL12_RS20445	COG2197	response regulator
CXL12_RS20450	COG2197	response regulator
CXL12_RS20455	COG2966	Psort location CytoplasmicMembrane, score
CXL12_RS20470	COG1484	DNA-dependent DNA replication
CXL12_RS20490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CXL12_RS20495	COG3716	PTS system mannose fructose sorbose family IID component
CXL12_RS20500	COG3715	PTS system
CXL12_RS20505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL12_RS20520	COG0840	transmembrane signaling receptor activity
CXL12_RS20525	COG1966	Carbon starvation protein
CXL12_RS20530	COG2879	small protein
CXL12_RS20535	COG0523	cobalamin synthesis protein
CXL12_RS20555	COG0732	type I restriction modification DNA specificity domain
CXL12_RS20570	COG3586	endonuclease activity
CXL12_RS20585	COG1012	belongs to the aldehyde dehydrogenase family
CXL12_RS20590	COG5464	transposase or invertase
CXL12_RS20600	COG2733	membrane
CXL12_RS20605	COG0477	Major facilitator Superfamily
CXL12_RS20610	COG3366	ferrous iron transmembrane transporter activity
CXL12_RS20615	COG0700	Nucleoside recognition
CXL12_RS20620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXL12_RS20625	COG0583	DNA-binding transcription factor activity
CXL12_RS20650	COG2186	Transcriptional regulator
CXL12_RS20660	COG0412	Dienelactone hydrolase
CXL12_RS20695	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CXL12_RS20715	COG0720	synthase
CXL12_RS20750	COG0514	ATP-dependent DNA helicase (RecQ)
CXL12_RS20755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CXL12_RS20815	COG1064	alcohol dehydrogenase
CXL12_RS20820	COG3265	gluconokinase activity
CXL12_RS20825	COG1063	alcohol dehydrogenase
CXL12_RS20830	COG1028	Short-chain dehydrogenase reductase Sdr
CXL12_RS20835	COG2610	gluconate transmembrane transporter activity
CXL12_RS20840	COG1609	Transcriptional regulator
CXL12_RS20845	COG0795	lipopolysaccharide-transporting ATPase activity
CXL12_RS20850	COG0795	lipopolysaccharide-transporting ATPase activity
CXL12_RS20870	COG2927	DNA polymerase III (CHI subunit)
CXL12_RS20910	COG2731	YhcH YjgK YiaL family protein
CXL12_RS20935	COG1288	antiporter activity
CXL12_RS20940	COG1438	arginine binding
CXL12_RS20990	COG1263	PTS System
CXL12_RS20990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL12_RS20995	COG0366	Alpha amylase catalytic
CXL12_RS21010	COG2026	Addiction module toxin, RelE StbE family
CXL12_RS21015	COG3077	Addiction module antitoxin, RelB DinJ family
CXL12_RS21020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL12_RS21020	COG3711	transcriptional antiterminator
CXL12_RS21035	COG3964	amidohydrolase
CXL12_RS21070	COG0312	modulator of DNA gyrase
CXL12_RS21080	COG1082	Xylose isomerase domain protein TIM barrel
CXL12_RS21090	COG2814	Major facilitator Superfamily
CXL12_RS21095	COG0673	inositol 2-dehydrogenase activity
CXL12_RS21100	COG3962	Belongs to the TPP enzyme family
CXL12_RS21105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS21115	COG1082	Xylose isomerase domain protein TIM barrel
CXL12_RS21120	COG5520	Belongs to the glycosyl hydrolase 30 family
CXL12_RS21150	COG3718	enzyme involved in inositol metabolism
CXL12_RS21155	COG0477	Major facilitator Superfamily
CXL12_RS21155	COG2814	Major facilitator Superfamily
CXL12_RS21165	COG2814	Major facilitator Superfamily
CXL12_RS21165	COG0477	Major facilitator Superfamily
CXL12_RS21170	COG1737	Transcriptional regulator
CXL12_RS21170	COG0837	glucose binding
CXL12_RS21180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CXL12_RS21195	COG3964	amidohydrolase
CXL12_RS21200	COG2271	Major facilitator Superfamily
CXL12_RS21205	COG2105	PFAM AIG2 family protein
CXL12_RS21225	COG1253	flavin adenine dinucleotide binding
CXL12_RS21240	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CXL12_RS21260	COG1733	regulation of RNA biosynthetic process
CXL12_RS21265	COG0702	epimerase
CXL12_RS21270	COG0697	spore germination
CXL12_RS21280	COG1113	amino acid transport
CXL12_RS21285	COG0545	Peptidyl-prolyl cis-trans isomerase
CXL12_RS21295	COG3061	Opacity-associated protein A
CXL12_RS21310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CXL12_RS21380	COG1073	alpha beta
CXL12_RS21385	COG3650	response to hydrogen peroxide
CXL12_RS21395	COG1960	acyl-CoA dehydrogenase activity
CXL12_RS21400	COG0754	glutathionylspermidine amidase activity
CXL12_RS21405	COG5463	Belongs to the UPF0441 family
CXL12_RS21410	COG3766	membrane
CXL12_RS21425	COG1842	Phage shock protein A
CXL12_RS21430	COG3789	protein conserved in bacteria
CXL12_RS21440	COG0557	exoribonuclease II activity
CXL12_RS21460	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CXL12_RS21465	COG0330	HflC and HflK could
CXL12_RS21470	COG0330	HflC and HflK could
CXL12_RS21475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CXL12_RS21500	COG0802	atpase or kinase
CXL12_RS21505	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CXL12_RS21505	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CXL12_RS21530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL12_RS21550	COG3264	Mechanosensitive ion channel
CXL12_RS21550	COG1511	domain protein
CXL12_RS21570	COG1053	succinate dehydrogenase
CXL12_RS21575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXL12_RS21605	COG5510	response to toxic substance
CXL12_RS21650	COG0531	amino acid
CXL12_RS21655	COG3030	protein affecting phage T7 exclusion by the F plasmid
CXL12_RS21660	COG1027	Aspartate ammonia-lyase
CXL12_RS21665	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXL12_RS21680	COG1309	transcriptional regulator
CXL12_RS21780	COG2197	response regulator
CXL12_RS21785	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CXL12_RS21805	COG3381	protein complex oligomerization
CXL12_RS21810	COG3302	dmso reductase anchor subunit
CXL12_RS21815	COG0437	4 iron, 4 sulfur cluster binding
CXL12_RS21820	COG0243	molybdopterin cofactor binding
CXL12_RS21825	COG3290	protein histidine kinase activity
CXL12_RS21830	COG4565	transcriptional regulatory protein
CXL12_RS21840	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CXL12_RS21845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CXL12_RS21845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CXL12_RS21860	COG2169	Transcriptional regulator
CXL12_RS21865	COG1982	Orn Lys Arg decarboxylase major
CXL12_RS21870	COG2207	Transcriptional regulator
CXL12_RS21875	COG0531	amino acid
CXL12_RS21905	COG2824	Alkylphosphonate utilization operon protein PhnA
CXL12_RS21910	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CXL12_RS21930	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CXL12_RS21935	COG1301	dicarboxylic acid transport
CXL12_RS21940	COG4235	cytochrome complex assembly
CXL12_RS21945	COG1138	Cytochrome C-type biogenesis protein
CXL12_RS21950	COG3301	Polysulphide reductase, NrfD
CXL12_RS21955	COG0437	4 iron, 4 sulfur cluster binding
CXL12_RS21960	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CXL12_RS21975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXL12_RS21980	COG3162	membrane
CXL12_RS21990	COG1346	cytolysis
CXL12_RS21995	COG1380	Effector of murein hydrolase LrgA
CXL12_RS22000	COG0583	DNA-binding transcription factor activity
CXL12_RS22005	COG0025	NhaP-type Na H and K H
CXL12_RS22015	COG2252	PERMEase
CXL12_RS22040	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CXL12_RS22105	COG2315	Protein conserved in bacteria
CXL12_RS22150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXL12_RS22160	COG0735	belongs to the Fur family
CXL12_RS22175	COG0534	Mate efflux family protein
CXL12_RS22185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CXL12_RS22225	COG1175	transmembrane transport
CXL12_RS22230	COG3833	ABC-type maltose transport systems, permease component
CXL12_RS22240	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXL12_RS22265	COG0527	aspartate kinase activity
CXL12_RS22350	COG2246	polysaccharide biosynthetic process
CXL12_RS22380	COG5301	cellulose 1,4-beta-cellobiosidase activity
CXL12_RS22420	COG3122	Protein conserved in bacteria
CXL12_RS22465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CXL12_RS22505	COG0151	Belongs to the GarS family
CXL12_RS22570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXL12_RS22575	COG2104	thiamine diphosphate biosynthetic process
CXL12_RS22645	COG0250	Participates in transcription elongation, termination and antitermination
CXL12_RS22700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CXL12_RS22760	COG0583	DNA-binding transcription factor activity
CXL12_RS22805	COG2207	Transcriptional regulator
CXL12_RS22815	COG0371	Dehydrogenase
CXL12_RS22820	COG3738	Protein conserved in bacteria
CXL12_RS22835	COG0737	Belongs to the 5'-nucleotidase family
CXL12_RS22850	COG0668	transmembrane transport
CXL12_RS22855	COG0527	aspartate kinase activity
CXL12_RS22855	COG0460	homoserine dehydrogenase
CXL12_RS22860	COG0626	cystathionine gamma-synthase activity
CXL12_RS22885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXL12_RS22890	COG1609	Transcriptional regulator
CXL12_RS22895	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXL12_RS22910	COG1575	Belongs to the MenA family. Type 1 subfamily
CXL12_RS22925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CXL12_RS22935	COG1494	fructose-1,6-bisphosphatase
CXL12_RS22945	COG3152	Membrane
CXL12_RS23000	COG1070	Carbohydrate kinase
CXL12_RS23010	COG2134	cdp-diacylglycerol pyrophosphatase
CXL12_RS23020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXL12_RS23030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS23035	COG2211	Major facilitator Superfamily
CXL12_RS23060	COG3678	ATP-independent chaperone mediated protein folding
CXL12_RS23065	COG0745	RESPONSE REGULATOR receiver
CXL12_RS23070	COG2205	protein histidine kinase activity
CXL12_RS23080	COG2258	MOSC domain
CXL12_RS23095	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXL12_RS23135	COG4806	L-rhamnose isomerase
CXL12_RS23145	COG1454	alcohol dehydrogenase
CXL12_RS23160	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CXL12_RS23185	COG3383	formate dehydrogenase (NAD+) activity
CXL12_RS23185	COG0243	molybdopterin cofactor binding
CXL12_RS23190	COG3383	formate dehydrogenase (NAD+) activity
CXL12_RS23190	COG0243	molybdopterin cofactor binding
CXL12_RS23195	COG0437	4 iron, 4 sulfur cluster binding
CXL12_RS23200	COG2864	formate dehydrogenase
CXL12_RS23215	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CXL12_RS23225	COG4680	protein conserved in bacteria
CXL12_RS23230	COG5499	transcription regulator containing HTH domain
CXL12_RS23235	COG0456	acetyltransferase
CXL12_RS23250	COG1011	Hydrolase
CXL12_RS23255	COG1349	DNA-binding transcription factor activity
CXL12_RS23260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS23270	COG3684	Belongs to the aldolase LacD family
CXL12_RS23280	COG2017	converts alpha-aldose to the beta-anomer
CXL12_RS23285	COG1501	Belongs to the glycosyl hydrolase 31 family
CXL12_RS23330	COG0561	phosphatase activity
CXL12_RS23395	COG0204	Acyl-transferase
CXL12_RS23410	COG3084	Protein conserved in bacteria
CXL12_RS23415	COG0746	molybdenum cofactor guanylyltransferase activity
CXL12_RS23420	COG1763	Mo-molybdopterin cofactor biosynthetic process
CXL12_RS23460	COG1739	Uncharacterized protein family UPF0029
CXL12_RS23505	COG0805	protein transport
CXL12_RS23550	COG0641	radical SAM
CXL12_RS23570	COG0561	phosphatase activity
CXL12_RS23575	COG2267	carboxylic ester hydrolase activity
CXL12_RS23580	COG1280	lysine exporter protein (LysE YggA)
CXL12_RS23635	COG1011	Hydrolase
CXL12_RS23695	COG2959	enzyme of heme biosynthesis
CXL12_RS23700	COG3071	HemY protein
CXL12_RS23745	COG2244	polysaccharide biosynthetic process
CXL12_RS23750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXL12_RS23755	COG0456	acetyltransferase
CXL12_RS23760	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CXL12_RS23765	COG1088	dTDP-glucose 4,6-dehydratase activity
CXL12_RS23770	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CXL12_RS23785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXL12_RS23805	COG3118	belongs to the thioredoxin family
CXL12_RS23885	COG3978	acetolactate synthase activity
CXL12_RS23945	COG2186	Transcriptional regulator
CXL12_RS23950	COG0477	Major facilitator Superfamily
CXL12_RS23955	COG1609	Transcriptional regulator
CXL12_RS23960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL12_RS23970	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXL12_RS24005	COG1522	sequence-specific DNA binding
CXL12_RS24010	COG0716	FMN binding
CXL12_RS24030	COG3312	ion transport
CXL12_RS24090	COG4533	DNA binding
CXL12_RS24095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CXL12_RS24100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXL12_RS24100	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CXL12_RS24100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXL12_RS24105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXL12_RS24110	COG0573	inorganic phosphate transmembrane transporter activity
CXL12_RS24115	COG0581	inorganic phosphate transmembrane transporter activity
CXL12_RS24125	COG0704	Plays a role in the regulation of phosphate uptake
CXL12_RS24130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXL12_RS24140	COG2252	PERMEase
CXL12_RS24145	COG0431	NADPH-dependent FMN reductase
CXL12_RS24150	COG2091	lysine biosynthetic process via aminoadipic acid
CXL12_RS24190	COG0582	viral genome integration into host DNA