locus-tag	class	description
STho1984_RS00010	COG0460	homoserine dehydrogenase
STho1984_RS00010	COG0527	aspartate kinase activity
STho1984_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
STho1984_RS00030	COG1115	amino acid carrier protein
STho1984_RS00040	COG0521	Mo-molybdopterin cofactor biosynthetic process
STho1984_RS00045	COG1584	GPR1 FUN34 yaaH family protein
STho1984_RS00050	COG4735	regulation of single-species biofilm formation
STho1984_RS00120	COG3188	usher protein
STho1984_RS00135	COG3539	Fimbrial protein
STho1984_RS00140	COG3121	Chaperone
STho1984_RS00160	COG0583	DNA-binding transcription factor activity
STho1984_RS00175	COG0737	Belongs to the 5'-nucleotidase family
STho1984_RS00185	COG3119	arylsulfatase activity
STho1984_RS00190	COG0641	radical SAM
STho1984_RS00210	COG0583	DNA-binding transcription factor activity
STho1984_RS00235	COG0196	riboflavin kinase activity
STho1984_RS00250	COG1047	Peptidyl-prolyl cis-trans
STho1984_RS00400	COG0644	oxidoreductase
STho1984_RS00405	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
STho1984_RS00410	COG2271	Major facilitator Superfamily
STho1984_RS00435	COG3119	arylsulfatase activity
STho1984_RS00470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
STho1984_RS00500	COG0417	DNA replication proofreading
STho1984_RS00535	COG0586	Pfam SNARE associated Golgi protein
STho1984_RS00630	COG0768	penicillin binding
STho1984_RS00640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STho1984_RS00655	COG0772	Belongs to the SEDS family
STho1984_RS00680	COG0849	cell division
STho1984_RS00685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
STho1984_RS00705	COG0494	nUDIX hydrolase
STho1984_RS00710	COG0667	Aldo Keto reductase
STho1984_RS00715	COG0583	DNA-binding transcription factor activity
STho1984_RS00740	COG1459	type II secretion system
STho1984_RS00745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STho1984_RS00750	COG4969	Belongs to the N-Me-Phe pilin family
STho1984_RS00765	COG3725	Membrane protein required for beta-lactamase induction
STho1984_RS00770	COG3940	Belongs to the glycosyl hydrolase 43 family
STho1984_RS00775	COG2211	Major facilitator Superfamily
STho1984_RS00790	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
STho1984_RS00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
STho1984_RS00800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STho1984_RS00815	COG3064	Membrane
STho1984_RS00885	COG1349	DNA-binding transcription factor activity
STho1984_RS00910	COG4993	Dehydrogenase
STho1984_RS00920	COG0288	reversible hydration of carbon dioxide
STho1984_RS00925	COG1131	(ABC) transporter
STho1984_RS00930	COG0842	Transport permease protein
STho1984_RS00935	COG3539	Fimbrial protein
STho1984_RS00955	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS00960	COG0726	polysaccharide deacetylase
STho1984_RS00980	COG3539	Fimbrial protein
STho1984_RS00985	COG3188	usher protein
STho1984_RS00990	COG3121	Chaperone
STho1984_RS01015	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
STho1984_RS01040	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
STho1984_RS01045	COG1643	Atp-dependent helicase
STho1984_RS01050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STho1984_RS01055	COG4774	siderophore transport
STho1984_RS01060	COG1120	ATPase activity
STho1984_RS01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
STho1984_RS01080	COG3188	usher protein
STho1984_RS01085	COG3121	Chaperone
STho1984_RS01090	COG3539	Fimbrial protein
STho1984_RS01095	COG3539	Fimbrial protein
STho1984_RS01125	COG2860	membrane
STho1984_RS01150	COG3835	regulator
STho1984_RS01160	COG0477	Major facilitator Superfamily
STho1984_RS01210	COG0575	Belongs to the CDS family
STho1984_RS01270	COG1982	Orn Lys Arg decarboxylase major
STho1984_RS01275	COG0346	lactoylglutathione lyase activity
STho1984_RS01280	COG0037	tRNA processing
STho1984_RS01285	COG4568	rho-dependent transcription termination
STho1984_RS01300	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STho1984_RS01305	COG3015	lipoprotein NlpE involved in copper resistance
STho1984_RS01315	COG1720	tRNA m6t6A37 methyltransferase activity
STho1984_RS01340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
STho1984_RS01380	COG0583	DNA-binding transcription factor activity
STho1984_RS01385	COG2814	Major facilitator Superfamily
STho1984_RS01395	COG2226	methyltransferase
STho1984_RS01400	COG1388	LysM domain
STho1984_RS01400	COG0741	lytic transglycosylase activity
STho1984_RS01410	COG2226	methyltransferase
STho1984_RS01515	COG3047	cAMP biosynthetic process
STho1984_RS01515	COG2885	chlorophyll binding
STho1984_RS01570	COG4104	PAAR repeat-containing protein
STho1984_RS01570	COG3209	COG3209 Rhs family protein
STho1984_RS01580	COG3209	COG3209 Rhs family protein
STho1984_RS01590	COG3209	COG3209 Rhs family protein
STho1984_RS01600	COG3209	COG3209 Rhs family protein
STho1984_RS01605	COG3209	COG3209 Rhs family protein
STho1984_RS01615	COG3209	COG3209 Rhs family protein
STho1984_RS01640	COG2963	transposase activity
STho1984_RS01710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STho1984_RS01725	COG0121	glutamine amidotransferase
STho1984_RS01730	COG3034	peptidoglycan biosynthetic process
STho1984_RS01740	COG1690	Belongs to the RtcB family
STho1984_RS01745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STho1984_RS01750	COG2195	Cleaves the N-terminal amino acid of tripeptides
STho1984_RS01790	COG2801	Transposase and inactivated derivatives
STho1984_RS01810	COG2814	Major facilitator Superfamily
STho1984_RS01825	COG0179	Fumarylacetoacetate (FAA) hydrolase
STho1984_RS01860	COG3188	usher protein
STho1984_RS01865	COG3121	Chaperone
STho1984_RS01870	COG3539	Fimbrial protein
STho1984_RS01885	COG2200	EAL domain
STho1984_RS01940	COG0789	Transcriptional regulator
STho1984_RS01955	COG2814	Major facilitator Superfamily
STho1984_RS01975	COG1271	oxidase subunit
STho1984_RS01980	COG1294	oxidase, subunit
STho1984_RS02000	COG1280	lysine exporter protein (LysE YggA)
STho1984_RS02035	COG0113	porphobilinogen synthase activity
STho1984_RS02050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
STho1984_RS02055	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
STho1984_RS02100	COG3706	GGDEF domain
STho1984_RS02105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
STho1984_RS02125	COG4126	flavin adenine dinucleotide binding
STho1984_RS02140	COG1940	carbohydrate kinase activity
STho1984_RS02145	COG2814	Major facilitator Superfamily
STho1984_RS02150	COG0419	ATPase involved in DNA repair
STho1984_RS02155	COG0420	3'-5' exonuclease activity
STho1984_RS02170	COG5002	protein histidine kinase activity
STho1984_RS02185	COG0366	Alpha amylase catalytic
STho1984_RS02190	COG0450	alkyl hydroperoxide reductase
STho1984_RS02210	COG1862	Preprotein translocase
STho1984_RS02220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
STho1984_RS02250	COG4238	major outer membrane lipoprotein
STho1984_RS02260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
STho1984_RS02260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
STho1984_RS02275	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
STho1984_RS02280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
STho1984_RS02285	COG0667	Aldo Keto reductase
STho1984_RS02295	COG0142	geranyltranstransferase activity
STho1984_RS02330	COG2188	Transcriptional regulator
STho1984_RS02360	COG2814	Major facilitator Superfamily
STho1984_RS02380	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
STho1984_RS02385	COG1845	cytochrome c oxidase, subunit III
STho1984_RS02390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
STho1984_RS02395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
STho1984_RS02400	COG2223	nitrite transmembrane transporter activity
STho1984_RS02405	COG3056	Lipoprotein
STho1984_RS02410	COG0271	Belongs to the BolA IbaG family
STho1984_RS02430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
STho1984_RS02440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
STho1984_RS02445	COG1555	photosystem II stabilization
STho1984_RS02450	COG0824	Thioesterase
STho1984_RS02460	COG4533	DNA binding
STho1984_RS02465	COG0561	phosphatase activity
STho1984_RS02475	COG1522	sequence-specific DNA binding
STho1984_RS02480	COG1132	(ABC) transporter
STho1984_RS02485	COG1132	(ABC) transporter
STho1984_RS02490	COG0347	Belongs to the P(II) protein family
STho1984_RS02495	COG0004	ammonium transporteR
STho1984_RS02500	COG1946	Acyl-CoA thioesterase
STho1984_RS02505	COG3126	Type III secretion system lipoprotein chaperone (YscW)
STho1984_RS02510	COG3695	enzyme binding
STho1984_RS02515	COG4943	cyclic-guanylate-specific phosphodiesterase activity
STho1984_RS02535	COG0110	maltose O-acetyltransferase activity
STho1984_RS02550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
STho1984_RS02555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STho1984_RS02560	COG1309	transcriptional regulator
STho1984_RS02565	COG3264	Mechanosensitive ion channel
STho1984_RS02565	COG1196	nuclear chromosome segregation
STho1984_RS02575	COG5464	transposase or invertase
STho1984_RS02585	COG3923	Primosomal replication protein n
STho1984_RS02590	COG2832	Protein of unknown function (DUF454)
STho1984_RS02635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS02640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
STho1984_RS02640	COG4651	solute:proton antiporter activity
STho1984_RS02645	COG2223	nitrite transmembrane transporter activity
STho1984_RS02660	COG3735	TraB family
STho1984_RS02670	COG2217	Heavy metal translocating P-type atpase
STho1984_RS02680	COG1585	Membrane protein implicated in regulation of membrane protease activity
STho1984_RS02685	COG0330	HflC and HflK could
STho1984_RS02690	COG4619	ABC transporter
STho1984_RS02695	COG0390	transport system, permease component
STho1984_RS02700	COG3118	belongs to the thioredoxin family
STho1984_RS02705	COG0300	oxidoreductase activity
STho1984_RS02710	COG2755	lipolytic protein G-D-S-L family
STho1984_RS02715	COG4181	ATPase activity
STho1984_RS02720	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
STho1984_RS02730	COG1464	Belongs to the NlpA lipoprotein family
STho1984_RS02765	COG3960	tartronate-semialdehyde synthase activity
STho1984_RS02770	COG3622	Belongs to the hyi family
STho1984_RS02775	COG2084	Dehydrogenase
STho1984_RS02785	COG1953	Uracil, thiamine, allantoin
STho1984_RS02795	COG2233	PERMEase
STho1984_RS02800	COG1929	Belongs to the glycerate kinase type-1 family
STho1984_RS02805	COG3257	ureidoglycine aminohydrolase activity
STho1984_RS02810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
STho1984_RS02815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
STho1984_RS02820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
STho1984_RS02825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
STho1984_RS02835	COG0549	Belongs to the carbamate kinase family
STho1984_RS02840	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
STho1984_RS02845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STho1984_RS02855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
STho1984_RS02875	COG1988	membrane-bound metal-dependent
STho1984_RS02880	COG2501	S4 domain
STho1984_RS02955	COG2246	polysaccharide biosynthetic process
STho1984_RS02960	COG0463	Glycosyl transferase, family 2
STho1984_RS02995	COG0463	Glycosyl transferase, family 2
STho1984_RS03000	COG2246	polysaccharide biosynthetic process
STho1984_RS03010	COG5002	protein histidine kinase activity
STho1984_RS03015	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
STho1984_RS03020	COG2207	Transcriptional regulator
STho1984_RS03025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STho1984_RS03035	COG3059	membrane
STho1984_RS03045	COG1113	amino acid transport
STho1984_RS03050	COG0668	transmembrane transport
STho1984_RS03065	COG2315	Protein conserved in bacteria
STho1984_RS03090	COG2977	Belongs to the P-Pant transferase superfamily
STho1984_RS03095	COG4771	TonB-dependent receptor
STho1984_RS03100	COG2382	esterase
STho1984_RS03105	COG3251	PFAM MbtH domain protein
STho1984_RS03110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
STho1984_RS03110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
STho1984_RS03115	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
STho1984_RS03120	COG1120	ATPase activity
STho1984_RS03125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STho1984_RS03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STho1984_RS03140	COG4592	Periplasmic binding protein
STho1984_RS03145	COG1169	isochorismate synthase
STho1984_RS03150	COG1021	2,3-dihydroxybenzoate-AMP ligase
STho1984_RS03155	COG3433	isochorismatase activity
STho1984_RS03155	COG1535	isochorismatase
STho1984_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
STho1984_RS03170	COG1966	Carbon starvation protein
STho1984_RS03175	COG2879	small protein
STho1984_RS03180	COG0371	Dehydrogenase
STho1984_RS03185	COG0436	Aminotransferase
STho1984_RS03190	COG1475	DNA binding
STho1984_RS03195	COG3969	phosphoadenosine phosphosulfate
STho1984_RS03200	COG0583	DNA-binding transcription factor activity
STho1984_RS03205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
STho1984_RS03225	COG0243	molybdopterin cofactor binding
STho1984_RS03245	COG1063	alcohol dehydrogenase
STho1984_RS03250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
STho1984_RS03255	COG3719	Belongs to the RNase T2 family
STho1984_RS03260	COG0471	metal ion transport
STho1984_RS03275	COG3051	citrate lyase alpha subunit
STho1984_RS03280	COG2301	Belongs to the HpcH HpaI aldolase family
STho1984_RS03290	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
STho1984_RS03295	COG3290	protein histidine kinase activity
STho1984_RS03300	COG4565	transcriptional regulatory protein
STho1984_RS03305	COG3069	C4-dicarboxylate transmembrane transporter activity
STho1984_RS03325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STho1984_RS03340	COG0583	DNA-binding transcription factor activity
STho1984_RS03355	COG1686	Belongs to the peptidase S11 family
STho1984_RS03365	COG0772	Belongs to the SEDS family
STho1984_RS03370	COG0768	penicillin binding
STho1984_RS03380	COG0799	negative regulation of ribosome biogenesis
STho1984_RS03405	COG1466	dna polymerase III delta subunit
STho1984_RS03435	COG3829	transcription factor binding
STho1984_RS03435	COG3290	protein histidine kinase activity
STho1984_RS03440	COG2888	peptidyl-tyrosine sulfation
STho1984_RS03455	COG2214	Heat shock protein DnaJ domain protein
STho1984_RS03465	COG2214	Heat shock protein DnaJ domain protein
STho1984_RS03470	COG0443	Heat shock 70 kDa protein
STho1984_RS03485	COG1126	abc transporter atp-binding protein
STho1984_RS03490	COG0765	amino acid transport
STho1984_RS03495	COG0765	amino acid transport
STho1984_RS03520	COG1702	phosphate starvation-inducible protein PhoH
STho1984_RS03530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
STho1984_RS03570	COG0367	asparagine synthase
STho1984_RS03575	COG0647	UMP catabolic process
STho1984_RS03580	COG1940	carbohydrate kinase activity
STho1984_RS03580	COG1846	Transcriptional regulator
STho1984_RS03585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
STho1984_RS03625	COG1053	succinate dehydrogenase
STho1984_RS03630	COG0583	DNA-binding transcription factor activity
STho1984_RS03635	COG0735	belongs to the Fur family
STho1984_RS03650	COG0596	Alpha beta hydrolase
STho1984_RS03660	COG0033	Phosphoglucomutase
STho1984_RS03670	COG0531	amino acid
STho1984_RS03675	COG1982	Orn Lys Arg decarboxylase major
STho1984_RS03685	COG0745	RESPONSE REGULATOR receiver
STho1984_RS03690	COG2205	protein histidine kinase activity
STho1984_RS03735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
STho1984_RS03740	COG1984	allophanate hydrolase subunit 2
STho1984_RS03755	COG3180	Ammonia monooxygenase
STho1984_RS03775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
STho1984_RS03790	COG0567	Dehydrogenase, E1 component
STho1984_RS03795	COG0508	dehydrogenase complex catalyzes the overall conversion of
STho1984_RS03805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
STho1984_RS03815	COG1271	oxidase subunit
STho1984_RS03820	COG1294	oxidase, subunit
STho1984_RS03825	COG4890	Cyd operon protein YbgT
STho1984_RS03830	COG3790	cyd operon protein YbgE
STho1984_RS03835	COG0824	Thioesterase
STho1984_RS03840	COG0811	peptide transport
STho1984_RS03845	COG0848	biopolymer transport protein
STho1984_RS03850	COG3064	Membrane
STho1984_RS03860	COG2885	chlorophyll binding
STho1984_RS03865	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
STho1984_RS03905	COG1230	cation diffusion facilitator family transporter
STho1984_RS03915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STho1984_RS03920	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
STho1984_RS03920	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
STho1984_RS03930	COG0583	DNA-binding transcription factor activity
STho1984_RS03935	COG0583	DNA-binding transcription factor activity
STho1984_RS03940	COG0490	domain, Protein
STho1984_RS03940	COG0471	metal ion transport
STho1984_RS03965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STho1984_RS03970	COG1120	ATPase activity
STho1984_RS03980	COG2017	converts alpha-aldose to the beta-anomer
STho1984_RS04005	COG1119	ATPase activity
STho1984_RS04010	COG2005	Transcriptional regulator
STho1984_RS04010	COG3585	molybdate ion transport
STho1984_RS04020	COG0725	ABC transporter, periplasmic molybdate-binding protein
STho1984_RS04025	COG4149	molybdate abc transporter
STho1984_RS04035	COG0561	phosphatase activity
STho1984_RS04045	COG4677	pectinesterase activity
STho1984_RS04075	COG1881	PFAM PEBP family protein
STho1984_RS04130	COG0521	Mo-molybdopterin cofactor biosynthetic process
STho1984_RS04140	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
STho1984_RS04150	COG0670	Belongs to the BI1 family
STho1984_RS04170	COG0392	lysyltransferase activity
STho1984_RS04175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STho1984_RS04180	COG3568	Endonuclease Exonuclease Phosphatase
STho1984_RS04190	COG0842	Transport permease protein
STho1984_RS04195	COG0842	Transport permease protein
STho1984_RS04200	COG1131	(ABC) transporter
STho1984_RS04210	COG1309	transcriptional regulator
STho1984_RS04215	COG0513	Belongs to the DEAD box helicase family
STho1984_RS04225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
STho1984_RS04240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
STho1984_RS04250	COG0668	transmembrane transport
STho1984_RS04255	COG1126	abc transporter atp-binding protein
STho1984_RS04260	COG0765	amino acid transport
STho1984_RS04265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STho1984_RS04280	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
STho1984_RS04285	COG2194	sulfuric ester hydrolase activity
STho1984_RS04295	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
STho1984_RS04300	COG1376	ErfK ybiS ycfS ynhG family protein
STho1984_RS04305	COG0488	(ABC) transporter
STho1984_RS04315	COG0561	phosphatase activity
STho1984_RS04325	COG0561	phosphatase activity
STho1984_RS04330	COG1882	Formate acetyltransferase
STho1984_RS04335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STho1984_RS04385	COG2301	Belongs to the HpcH HpaI aldolase family
STho1984_RS04400	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
STho1984_RS04405	COG1960	acyl-CoA dehydrogenase activity
STho1984_RS04415	COG0583	DNA-binding transcription factor activity
STho1984_RS04420	COG2610	gluconate transmembrane transporter activity
STho1984_RS04430	COG2133	pyrroloquinoline quinone binding
STho1984_RS04435	COG0625	glutathione transferase activity
STho1984_RS04440	COG1686	Belongs to the peptidase S11 family
STho1984_RS04445	COG1349	DNA-binding transcription factor activity
STho1984_RS04450	COG0671	phosphoesterase, PA-phosphatase related
STho1984_RS04455	COG2814	Major facilitator Superfamily
STho1984_RS04460	COG0561	phosphatase activity
STho1984_RS04465	COG0738	Major facilitator superfamily
STho1984_RS04470	COG3226	Transcriptional regulator
STho1984_RS04510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
STho1984_RS04515	COG3842	ATPase activity
STho1984_RS04520	COG1176	ABC-type spermidine putrescine transport system, permease component I
STho1984_RS04525	COG1177	transmembrane transport
STho1984_RS04555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STho1984_RS04560	COG4160	amino acid transport
STho1984_RS04565	COG4215	(ABC) transporter
STho1984_RS04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STho1984_RS04575	COG1126	abc transporter atp-binding protein
STho1984_RS04590	COG3023	N-Acetylmuramoyl-L-alanine amidase
STho1984_RS04595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
STho1984_RS04600	COG0702	epimerase
STho1984_RS04605	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
STho1984_RS04610	COG0028	Belongs to the TPP enzyme family
STho1984_RS04615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
STho1984_RS04625	COG2431	L-lysine efflux transmembrane transporter activity
STho1984_RS04630	COG3593	DNA synthesis involved in DNA repair
STho1984_RS04635	COG2990	Protein conserved in bacteria
STho1984_RS04640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STho1984_RS04650	COG1278	Cold shock
STho1984_RS04660	COG0542	response to heat
STho1984_RS04670	COG1335	isochorismatase
STho1984_RS04680	COG0583	DNA-binding transcription factor activity
STho1984_RS04700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
STho1984_RS04705	COG4988	ABC transporter
STho1984_RS04710	COG0492	ferredoxin-NADP+ reductase activity
STho1984_RS04730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
STho1984_RS04740	COG0243	molybdopterin cofactor binding
STho1984_RS04745	COG0437	4 iron, 4 sulfur cluster binding
STho1984_RS04750	COG3302	dmso reductase anchor subunit
STho1984_RS04765	COG0531	amino acid
STho1984_RS04770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STho1984_RS04780	COG1882	Formate acetyltransferase
STho1984_RS04785	COG2116	formate transmembrane transporter activity
STho1984_RS04790	COG1944	ATP diphosphatase activity
STho1984_RS04795	COG2323	membrane
STho1984_RS04810	COG0501	Belongs to the peptidase M48B family
STho1984_RS04820	COG0539	negative regulation of cytoplasmic translation
STho1984_RS04830	COG2333	competence protein COMEC
STho1984_RS04830	COG0658	competence protein
STho1984_RS04845	COG3214	Protein conserved in bacteria
STho1984_RS04860	COG3173	Aminoglycoside phosphotransferase
STho1984_RS04865	COG1434	Gram-negative-bacterium-type cell wall biogenesis
STho1984_RS04870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
STho1984_RS04880	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
STho1984_RS04890	COG2989	Protein conserved in bacteria
STho1984_RS04895	COG3108	Peptidase M15
STho1984_RS04900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
STho1984_RS04910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
STho1984_RS04915	COG0017	Asparaginyl-tRNA synthetase
STho1984_RS04920	COG1522	sequence-specific DNA binding
STho1984_RS04935	COG1115	amino acid carrier protein
STho1984_RS04945	COG0582	viral genome integration into host DNA
STho1984_RS04965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
STho1984_RS05010	COG1484	DNA-dependent DNA replication
STho1984_RS05065	COG0484	heat shock protein binding
STho1984_RS05110	COG4220	transposase activity
STho1984_RS05215	COG5301	cellulose 1,4-beta-cellobiosidase activity
STho1984_RS05240	COG0308	aminopeptidase N
STho1984_RS05255	COG0633	Ferredoxin
STho1984_RS05255	COG3217	Mosc domain protein beta barrel domain protein
STho1984_RS05265	COG0488	(ABC) transporter
STho1984_RS05270	COG2995	paraquat-inducible protein a
STho1984_RS05275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
STho1984_RS05275	COG3008	intermembrane lipid transfer
STho1984_RS05280	COG3009	Protein conserved in bacteria
STho1984_RS05285	COG3130	regulation of translation
STho1984_RS05295	COG1067	ATP-dependent peptidase activity
STho1984_RS05315	COG3070	regulator of competence-specific genes
STho1984_RS05320	COG1289	transmembrane transporter activity
STho1984_RS05325	COG3304	Inner membrane component domain
STho1984_RS05330	COG0210	DNA helicase
STho1984_RS05345	COG1832	CoA-binding protein
STho1984_RS05360	COG1881	PFAM PEBP family protein
STho1984_RS05380	COG0670	Belongs to the BI1 family
STho1984_RS05435	COG2205	protein histidine kinase activity
STho1984_RS05440	COG0745	RESPONSE REGULATOR receiver
STho1984_RS05455	COG2368	4-hydroxyphenylacetate
STho1984_RS05460	COG1846	Transcriptional regulator
STho1984_RS05470	COG1012	belongs to the aldehyde dehydrogenase family
STho1984_RS05475	COG3384	dioxygenase
STho1984_RS05485	COG3971	2-oxopent-4-enoate hydratase activity
STho1984_RS05530	COG4232	protein-disulfide reductase activity
STho1984_RS05535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
STho1984_RS05535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
STho1984_RS05540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STho1984_RS05560	COG3729	General stress protein
STho1984_RS05565	COG1309	transcriptional regulator
STho1984_RS05590	COG1702	phosphate starvation-inducible protein PhoH
STho1984_RS05595	COG1737	Transcriptional regulator
STho1984_RS05600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
STho1984_RS05620	COG2814	Major facilitator Superfamily
STho1984_RS05625	COG0673	inositol 2-dehydrogenase activity
STho1984_RS05655	COG3381	protein complex oligomerization
STho1984_RS05710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STho1984_RS05730	COG5645	(Lipo)protein
STho1984_RS05745	COG1560	Kdo2-lipid A biosynthetic process
STho1984_RS05760	COG3038	cytochrome b561
STho1984_RS05795	COG2999	glutathione oxidoreductase activity
STho1984_RS05805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STho1984_RS05895	COG1530	ribonuclease E activity
STho1984_RS05960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STho1984_RS05965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STho1984_RS05970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
STho1984_RS05980	COG0470	DNA polymerase III
STho1984_RS05985	COG0084	hydrolase, TatD family'
STho1984_RS05995	COG4773	Receptor
STho1984_RS06000	COG0537	adenosine 5'-monophosphoramidase activity
STho1984_RS06005	COG5633	Lipoprotein
STho1984_RS06030	COG1252	NADH dehydrogenase
STho1984_RS06035	COG3134	Outer membrane lipoprotein
STho1984_RS06040	COG1309	transcriptional regulator
STho1984_RS06050	COG1388	LysM domain
STho1984_RS06050	COG1376	ErfK ybiS ycfS ynhG family protein
STho1984_RS06055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
STho1984_RS06060	COG4591	ABC-type transport system involved in lipoprotein release permease component
STho1984_RS06065	COG1136	(ABC) transporter
STho1984_RS06070	COG4591	ABC-type transport system involved in lipoprotein release permease component
STho1984_RS06090	COG1177	transmembrane transport
STho1984_RS06120	COG2850	peptidyl-arginine hydroxylation
STho1984_RS06135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STho1984_RS06165	COG0538	isocitrate dehydrogenase activity
STho1984_RS06250	COG0071	Belongs to the small heat shock protein (HSP20) family
STho1984_RS06265	COG3038	cytochrome b561
STho1984_RS06295	COG1124	(ABC) transporter
STho1984_RS06300	COG0668	transmembrane transport
STho1984_RS06315	COG3443	Belongs to the bacterial solute-binding protein 9 family
STho1984_RS06330	COG0789	Transcriptional regulator
STho1984_RS06345	COG1605	Chorismate mutase
STho1984_RS06355	COG3615	Tellurite resistance protein tehB
STho1984_RS06375	COG2261	transglycosylase associated protein
STho1984_RS06380	COG3042	response to heat
STho1984_RS06390	COG3189	MarR family transcriptional regulator
STho1984_RS06395	COG2807	transmembrane transport
STho1984_RS06400	COG2207	Transcriptional regulator
STho1984_RS06415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
STho1984_RS06420	COG2199	diguanylate cyclase activity
STho1984_RS06430	COG2766	serine protein kinase
STho1984_RS06435	COG3713	MltA-interacting MipA family protein
STho1984_RS06440	COG0641	radical SAM
STho1984_RS06445	COG0656	L-ascorbic acid biosynthetic process
STho1984_RS06465	COG3139	Protein of unknown function (DUF1315)
STho1984_RS06470	COG1335	isochorismatase
STho1984_RS06475	COG0252	asparaginase activity
STho1984_RS06480	COG0616	signal peptide processing
STho1984_RS06485	COG0778	Nitroreductase
STho1984_RS06495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
STho1984_RS06510	COG0494	nUDIX hydrolase
STho1984_RS06545	COG3678	ATP-independent chaperone mediated protein folding
STho1984_RS06550	COG0322	excinuclease ABC activity
STho1984_RS06560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
STho1984_RS06565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STho1984_RS06570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STho1984_RS06575	COG1447	Phosphotransferase system cellobiose-specific component IIA
STho1984_RS06580	COG1917	Cupin 2, conserved barrel domain protein
STho1984_RS06580	COG2169	Transcriptional regulator
STho1984_RS06585	COG1486	melibiose metabolic process
STho1984_RS06595	COG0753	catalase activity
STho1984_RS06605	COG1823	symporter activity
STho1984_RS06610	COG1988	membrane-bound metal-dependent
STho1984_RS06615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STho1984_RS06625	COG3001	Fructosamine kinase
STho1984_RS06635	COG1105	Belongs to the carbohydrate kinase PfkB family
STho1984_RS06640	COG3137	Salt-induced outer membrane protein
STho1984_RS06700	COG0386	Belongs to the glutathione peroxidase family
STho1984_RS06710	COG0791	NLP P60 protein
STho1984_RS06725	COG4256	Hemin uptake protein
STho1984_RS06740	COG0574	Belongs to the PEP-utilizing enzyme family
STho1984_RS06740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
STho1984_RS06745	COG0318	PFAM AMP-dependent synthetase and ligase
STho1984_RS06750	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
STho1984_RS06755	COG0644	oxidoreductase
STho1984_RS06760	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
STho1984_RS06765	COG2086	electron transfer activity
STho1984_RS06770	COG1917	Cupin 2, conserved barrel domain protein
STho1984_RS06770	COG2207	Transcriptional regulator
STho1984_RS06775	COG1960	acyl-CoA dehydrogenase activity
STho1984_RS06780	COG4670	ketone body catabolic process
STho1984_RS06795	COG2271	Major facilitator Superfamily
STho1984_RS06800	COG0738	Major facilitator superfamily
STho1984_RS06810	COG0628	permease
STho1984_RS06815	COG0247	lactate metabolic process
STho1984_RS06815	COG0277	FAD linked oxidase domain protein
STho1984_RS06820	COG2050	protein possibly involved in aromatic compounds catabolism
STho1984_RS06830	COG1823	symporter activity
STho1984_RS06835	COG0316	Belongs to the HesB IscA family
STho1984_RS06840	COG0719	Fe-S assembly protein
STho1984_RS06845	COG0396	ATPase activity
STho1984_RS06850	COG0719	Fe-S assembly protein
STho1984_RS06865	COG1376	ErfK ybiS ycfS ynhG family protein
STho1984_RS06870	COG4238	major outer membrane lipoprotein
STho1984_RS06890	COG0531	amino acid
STho1984_RS06895	COG2267	carboxylic ester hydrolase activity
STho1984_RS06905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS06940	COG3272	Protein of unknown function (DUF1722)
STho1984_RS06945	COG0789	Transcriptional regulator
STho1984_RS07125	COG0307	riboflavin synthase, alpha
STho1984_RS07130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
STho1984_RS07135	COG2814	Major facilitator Superfamily
STho1984_RS07140	COG0583	DNA-binding transcription factor activity
STho1984_RS07155	COG0791	NLP P60 protein
STho1984_RS07160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
STho1984_RS07175	COG1902	pentaerythritol trinitrate reductase activity
STho1984_RS07180	COG1309	transcriptional regulator
STho1984_RS07185	COG3313	Fe-S protein
STho1984_RS07190	COG4989	oxidoreductase activity
STho1984_RS07205	COG1566	PFAM secretion protein HlyD family protein
STho1984_RS07230	COG3895	Periplasmic Protein
STho1984_RS07250	COG0625	glutathione transferase activity
STho1984_RS07260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STho1984_RS07310	COG0673	inositol 2-dehydrogenase activity
STho1984_RS07320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
STho1984_RS07325	COG1263	PTS System
STho1984_RS07325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STho1984_RS07330	COG1609	Transcriptional regulator
STho1984_RS07335	COG5339	Protein conserved in bacteria
STho1984_RS07360	COG2205	protein histidine kinase activity
STho1984_RS07365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
STho1984_RS07370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
STho1984_RS07380	COG0745	RESPONSE REGULATOR receiver
STho1984_RS07385	COG3136	membrane protein required for alginate biosynthesis
STho1984_RS07390	COG0531	amino acid
STho1984_RS07400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
STho1984_RS07405	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
STho1984_RS07410	COG0628	permease
STho1984_RS07425	COG3591	Belongs to the peptidase S1B family
STho1984_RS07435	COG2814	Major facilitator Superfamily
STho1984_RS07440	COG0583	DNA-binding transcription factor activity
STho1984_RS07445	COG1940	carbohydrate kinase activity
STho1984_RS07450	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
STho1984_RS07485	COG3302	dmso reductase anchor subunit
STho1984_RS07490	COG0437	4 iron, 4 sulfur cluster binding
STho1984_RS07495	COG0243	molybdopterin cofactor binding
STho1984_RS07500	COG0243	molybdopterin cofactor binding
STho1984_RS07515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STho1984_RS07535	COG1063	alcohol dehydrogenase
STho1984_RS07540	COG0477	Major facilitator Superfamily
STho1984_RS07545	COG0246	Mannitol dehydrogenase
STho1984_RS07555	COG1802	Transcriptional regulator
STho1984_RS07560	COG4221	oxidoreductase activity
STho1984_RS07570	COG3729	General stress protein
STho1984_RS07575	COG1546	Belongs to the CinA family
STho1984_RS07580	COG3111	PFAM Bacterial OB fold (BOF) protein
STho1984_RS07590	COG2814	Major facilitator Superfamily
STho1984_RS07625	COG0583	DNA-binding transcription factor activity
STho1984_RS07630	COG1012	belongs to the aldehyde dehydrogenase family
STho1984_RS07645	COG3781	membrane
STho1984_RS07670	COG1773	rubredoxin
STho1984_RS07695	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
STho1984_RS07700	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
STho1984_RS07710	COG2186	Transcriptional regulator
STho1984_RS07715	COG1063	alcohol dehydrogenase
STho1984_RS07720	COG2271	Major facilitator Superfamily
STho1984_RS07745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
STho1984_RS07750	COG0251	oxidation-reduction process
STho1984_RS07765	COG2801	Transposase and inactivated derivatives
STho1984_RS07780	COG1609	Transcriptional regulator
STho1984_RS07785	COG1757	Na H antiporter
STho1984_RS07790	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
STho1984_RS07805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
STho1984_RS07820	COG1764	response to oxidative stress
STho1984_RS07840	COG1064	alcohol dehydrogenase
STho1984_RS07845	COG2864	formate dehydrogenase
STho1984_RS07850	COG0437	4 iron, 4 sulfur cluster binding
STho1984_RS07855	COG0243	molybdopterin cofactor binding
STho1984_RS07855	COG3383	formate dehydrogenase (NAD+) activity
STho1984_RS07860	COG3383	formate dehydrogenase (NAD+) activity
STho1984_RS07860	COG0243	molybdopterin cofactor binding
STho1984_RS07895	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
STho1984_RS07900	COG1140	nitrate reductase beta subunit
STho1984_RS07905	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
STho1984_RS07910	COG2181	nitrate reductase activity
STho1984_RS07945	COG4772	TonB-dependent receptor
STho1984_RS07950	COG1802	Transcriptional regulator
STho1984_RS07955	COG2130	NADP-dependent
STho1984_RS07965	COG3238	Protein conserved in bacteria
STho1984_RS08000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
STho1984_RS08005	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
STho1984_RS08030	COG0826	peptidase U32
STho1984_RS08035	COG1396	sequence-specific DNA binding
STho1984_RS08040	COG3135	benzoate transporter
STho1984_RS08050	COG0500	methyltransferase
STho1984_RS08055	COG1275	C4-dicarboxylate transporter malic acid transport protein
STho1984_RS08060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
STho1984_RS08065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STho1984_RS08075	COG3414	Phosphotransferase system galactitol-specific IIB component
STho1984_RS08080	COG3775	system Galactitol-specific IIC component
STho1984_RS08085	COG0434	BtpA family
STho1984_RS08090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS08095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
STho1984_RS08100	COG1349	DNA-binding transcription factor activity
STho1984_RS08110	COG1304	FMN binding
STho1984_RS08115	COG2353	YceI-like domain
STho1984_RS08125	COG2272	Belongs to the type-B carboxylesterase lipase family
STho1984_RS08130	COG5383	Protein conserved in bacteria
STho1984_RS08135	COG0583	DNA-binding transcription factor activity
STho1984_RS08140	COG0840	transmembrane signaling receptor activity
STho1984_RS08170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STho1984_RS08175	COG0765	amino acid transport
STho1984_RS08185	COG0765	amino acid transport
STho1984_RS08195	COG0500	methyltransferase
STho1984_RS08200	COG3038	cytochrome b561
STho1984_RS08205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
STho1984_RS08210	COG1643	Atp-dependent helicase
STho1984_RS08225	COG3784	Protein of unknown function (DUF1318)
STho1984_RS08235	COG2911	Protein conserved in bacteria
STho1984_RS08240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
STho1984_RS08245	COG3187	Heat shock protein
STho1984_RS08250	COG3042	response to heat
STho1984_RS08260	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
STho1984_RS08260	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
STho1984_RS08260	COG1013	pyruvate-flavodoxin oxidoreductase activity
STho1984_RS08260	COG0674	pyruvate-flavodoxin oxidoreductase activity
STho1984_RS08270	COG2076	Multidrug Resistance protein
STho1984_RS08285	COG0513	Belongs to the DEAD box helicase family
STho1984_RS08295	COG0840	transmembrane signaling receptor activity
STho1984_RS08300	COG2840	Smr protein MutS2
STho1984_RS08320	COG3182	Iron-regulated membrane protein
STho1984_RS08325	COG0668	transmembrane transport
STho1984_RS08345	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
STho1984_RS08380	COG1309	transcriptional regulator
STho1984_RS08385	COG1028	Short-chain dehydrogenase reductase Sdr
STho1984_RS08390	COG0656	L-ascorbic acid biosynthetic process
STho1984_RS08395	COG0583	DNA-binding transcription factor activity
STho1984_RS08405	COG4166	transmembrane transport
STho1984_RS08410	COG2866	Carboxypeptidase
STho1984_RS08415	COG4948	Mandelate Racemase Muconate Lactonizing
STho1984_RS08435	COG3106	COG3106 Predicted ATPase
STho1984_RS08440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
STho1984_RS08450	COG1983	PspC domain protein
STho1984_RS08460	COG1842	Phage shock protein A
STho1984_RS08465	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
STho1984_RS08520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
STho1984_RS08520	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
STho1984_RS08530	COG5001	Diguanylate cyclase
STho1984_RS08540	COG1349	DNA-binding transcription factor activity
STho1984_RS08560	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
STho1984_RS08565	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
STho1984_RS08570	COG0671	phosphoesterase, PA-phosphatase related
STho1984_RS08605	COG0616	signal peptide processing
STho1984_RS08610	COG1028	Short-chain dehydrogenase reductase Sdr
STho1984_RS08625	COG0009	L-threonylcarbamoyladenylate synthase
STho1984_RS08660	COG3729	General stress protein
STho1984_RS08665	COG3685	Protein conserved in bacteria
STho1984_RS08670	COG3685	Protein conserved in bacteria
STho1984_RS08675	COG3546	catalase activity
STho1984_RS08685	COG0727	PFAM Uncharacterised protein family (UPF0153)
STho1984_RS08710	COG2350	Protein conserved in bacteria
STho1984_RS08725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
STho1984_RS08755	COG2095	MarC family integral membrane protein
STho1984_RS08760	COG1454	alcohol dehydrogenase
STho1984_RS08760	COG1012	belongs to the aldehyde dehydrogenase family
STho1984_RS08775	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STho1984_RS08780	COG0745	RESPONSE REGULATOR receiver
STho1984_RS08785	COG1752	Esterase of the alpha-beta hydrolase superfamily
STho1984_RS08795	COG0788	formyltetrahydrofolate deformylase activity
STho1984_RS08815	COG2181	nitrate reductase activity
STho1984_RS08820	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
STho1984_RS08825	COG1140	nitrate reductase beta subunit
STho1984_RS08830	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
STho1984_RS08835	COG2223	nitrite transmembrane transporter activity
STho1984_RS08840	COG3850	Histidine kinase
STho1984_RS08845	COG2197	response regulator
STho1984_RS08850	COG4932	domain protein
STho1984_RS08855	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
STho1984_RS08860	COG4572	Cation transport regulator
STho1984_RS08865	COG0387	Pfam Sodium calcium exchanger
STho1984_RS08905	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
STho1984_RS08915	COG0659	secondary active sulfate transmembrane transporter activity
STho1984_RS08930	COG0012	GTP binding
STho1984_RS08940	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
STho1984_RS08950	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
STho1984_RS08955	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
STho1984_RS08960	COG1999	signal sequence binding
STho1984_RS08965	COG1773	rubredoxin
STho1984_RS08970	COG1271	oxidase subunit
STho1984_RS08975	COG1294	oxidase, subunit
STho1984_RS08985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STho1984_RS09010	COG1619	proteins homologs of microcin C7 resistance protein MccF
STho1984_RS09030	COG2719	SpoVR family
STho1984_RS09070	COG0179	Fumarylacetoacetate (FAA) hydrolase
STho1984_RS09085	COG2894	cell division
STho1984_RS09095	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
STho1984_RS09105	COG3065	identical protein binding
STho1984_RS09115	COG1199	ATP-dependent helicase activity
STho1984_RS09120	COG0251	oxidation-reduction process
STho1984_RS09140	COG1760	l-serine dehydratase
STho1984_RS09145	COG2200	EAL domain
STho1984_RS09150	COG1253	flavin adenine dinucleotide binding
STho1984_RS09160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STho1984_RS09160	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS09165	COG3715	PTS system
STho1984_RS09170	COG3716	PTS system mannose fructose sorbose family IID component
STho1984_RS09185	COG2226	methyltransferase
STho1984_RS09190	COG0768	penicillin binding
STho1984_RS09220	COG1414	Transcriptional regulator
STho1984_RS09225	COG2814	Major facilitator Superfamily
STho1984_RS09245	COG1956	GAF domain-containing protein
STho1984_RS09250	COG2995	paraquat-inducible protein a
STho1984_RS09255	COG3008	intermembrane lipid transfer
STho1984_RS09290	COG5562	phage envelope protein
STho1984_RS09300	COG0454	-acetyltransferase
STho1984_RS09385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
STho1984_RS09405	COG1276	copper resistance
STho1984_RS09410	COG2372	response to copper ion
STho1984_RS09420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STho1984_RS09425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
STho1984_RS09430	COG1770	oligopeptidase
STho1984_RS09435	COG2979	Protein of unknown function (DUF533)
STho1984_RS09445	COG3141	response to X-ray
STho1984_RS09455	COG0800	Aldolase
STho1984_RS09460	COG0129	dihydroxy-acid dehydratase activity
STho1984_RS09465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
STho1984_RS09470	COG1737	Transcriptional regulator
STho1984_RS09480	COG1560	Kdo2-lipid A biosynthetic process
STho1984_RS09485	COG0739	heme binding
STho1984_RS09490	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
STho1984_RS09500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STho1984_RS09535	COG0494	nUDIX hydrolase
STho1984_RS09545	COG1335	isochorismatase
STho1984_RS09550	COG1801	Protein of unknown function DUF72
STho1984_RS09555	COG3788	relative of glutathione S-transferase, MAPEG superfamily
STho1984_RS09575	COG3102	Protein conserved in bacteria
STho1984_RS09590	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
STho1984_RS09690	COG1528	Iron-storage protein
STho1984_RS09705	COG1528	Iron-storage protein
STho1984_RS09715	COG0814	amino acid
STho1984_RS09720	COG3318	Belongs to the UPF0149 family
STho1984_RS09720	COG3012	SEC-C Motif Domain Protein
STho1984_RS09760	COG0322	excinuclease ABC activity
STho1984_RS09765	COG2197	response regulator
STho1984_RS09780	COG2197	response regulator
STho1984_RS09785	COG1126	abc transporter atp-binding protein
STho1984_RS09790	COG0765	amino acid transport
STho1984_RS09800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STho1984_RS09855	COG0425	Belongs to the sulfur carrier protein TusA family
STho1984_RS09960	COG5475	Uncharacterized small protein (DUF2158)
STho1984_RS09965	COG2354	Protein conserved in bacteria
STho1984_RS09970	COG0697	spore germination
STho1984_RS09975	COG3727	T/G mismatch-specific endonuclease activity
STho1984_RS09980	COG0270	DNA (cytosine-5-)-methyltransferase activity
STho1984_RS09985	COG1418	mRNA catabolic process
STho1984_RS09995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
STho1984_RS10035	COG0582	viral genome integration into host DNA
STho1984_RS10075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
STho1984_RS10105	COG0534	Mate efflux family protein
STho1984_RS10120	COG0798	PFAM Bile acid sodium symporter
STho1984_RS10135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
STho1984_RS10140	COG0640	Transcriptional regulator
STho1984_RS10170	COG1122	ATPase activity
STho1984_RS10300	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
STho1984_RS10315	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
STho1984_RS10370	COG1289	transmembrane transporter activity
STho1984_RS10405	COG2925	Exonuclease
STho1984_RS10410	COG0531	amino acid
STho1984_RS10415	COG0583	DNA-binding transcription factor activity
STho1984_RS10420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
STho1984_RS10505	COG0438	transferase activity, transferring glycosyl groups
STho1984_RS10535	COG2327	Polysaccharide pyruvyl transferase
STho1984_RS10540	COG2244	polysaccharide biosynthetic process
STho1984_RS10545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
STho1984_RS10560	COG0297	glycogen (starch) synthase activity
STho1984_RS10570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
STho1984_RS10575	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
STho1984_RS10580	COG0110	maltose O-acetyltransferase activity
STho1984_RS10585	COG1216	Glycosyl transferase, family 2
STho1984_RS10595	COG0438	transferase activity, transferring glycosyl groups
STho1984_RS10600	COG1045	serine acetyltransferase
STho1984_RS10605	COG0463	Glycosyl transferase, family 2
STho1984_RS10625	COG1253	flavin adenine dinucleotide binding
STho1984_RS10630	COG2982	Protein involved in outer membrane biogenesis
STho1984_RS10645	COG5002	protein histidine kinase activity
STho1984_RS10645	COG3447	MASE1 domain protein
STho1984_RS10645	COG5001	Diguanylate cyclase
STho1984_RS10650	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
STho1984_RS10655	COG0443	Heat shock 70 kDa protein
STho1984_RS10680	COG2205	protein histidine kinase activity
STho1984_RS10685	COG0745	RESPONSE REGULATOR receiver
STho1984_RS10730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
STho1984_RS10735	COG3209	COG3209 Rhs family protein
STho1984_RS10750	COG3209	COG3209 Rhs family protein
STho1984_RS10780	COG0826	peptidase U32
STho1984_RS10805	COG1830	Aldolase
STho1984_RS10810	COG2211	Major facilitator Superfamily
STho1984_RS10815	COG1397	ADP-ribosylglycohydrolase
STho1984_RS10820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS10825	COG2188	Transcriptional regulator
STho1984_RS10840	COG5455	response to cobalt ion
STho1984_RS10845	COG3539	Fimbrial protein
STho1984_RS10850	COG3188	usher protein
STho1984_RS10855	COG3121	Chaperone
STho1984_RS10880	COG4808	Protein conserved in bacteria
STho1984_RS10890	COG4807	Protein conserved in bacteria
STho1984_RS10900	COG3275	phosphorelay sensor kinase activity
STho1984_RS10915	COG1174	glycine betaine transport
STho1984_RS10920	COG1125	glycine betaine transport
STho1984_RS10925	COG1174	glycine betaine transport
STho1984_RS10930	COG1732	Glycine betaine
STho1984_RS10940	COG0277	FAD linked oxidase domain protein
STho1984_RS10945	COG1686	Belongs to the peptidase S11 family
STho1984_RS10955	COG0586	Pfam SNARE associated Golgi protein
STho1984_RS10960	COG1028	Short-chain dehydrogenase reductase Sdr
STho1984_RS10965	COG1538	Outer membrane efflux protein
STho1984_RS10975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
STho1984_RS10980	COG0625	glutathione transferase activity
STho1984_RS10995	COG2271	Major facilitator Superfamily
STho1984_RS11010	COG1346	cytolysis
STho1984_RS11020	COG2949	membrane
STho1984_RS11060	COG2311	Membrane
STho1984_RS11080	COG1760	l-serine dehydratase
STho1984_RS11085	COG0560	Phosphoserine phosphatase
STho1984_RS11090	COG2271	Major facilitator Superfamily
STho1984_RS11095	COG4771	TonB-dependent receptor
STho1984_RS11100	COG0833	amino acid
STho1984_RS11105	COG0583	DNA-binding transcription factor activity
STho1984_RS11110	COG2855	membrane
STho1984_RS11120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STho1984_RS11120	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
STho1984_RS11120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STho1984_RS11125	COG1105	Belongs to the carbohydrate kinase PfkB family
STho1984_RS11160	COG0523	cobalamin synthesis protein
STho1984_RS11165	COG0671	phosphoesterase, PA-phosphatase related
STho1984_RS11170	COG0791	NLP P60 protein
STho1984_RS11175	COG2200	EAL domain
STho1984_RS11180	COG4166	transmembrane transport
STho1984_RS11185	COG4174	ABC transporter (Permease)
STho1984_RS11190	COG4239	(ABC) transporter, permease
STho1984_RS11195	COG4172	Belongs to the ABC transporter superfamily
STho1984_RS11210	COG2814	Major facilitator Superfamily
STho1984_RS11220	COG1061	Type III restriction enzyme res subunit
STho1984_RS11265	COG5301	cellulose 1,4-beta-cellobiosidase activity
STho1984_RS11280	COG2197	response regulator
STho1984_RS11285	COG4235	cytochrome complex assembly
STho1984_RS11285	COG3088	subunit of a heme lyase
STho1984_RS11290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STho1984_RS11295	COG1138	Cytochrome C-type biogenesis protein
STho1984_RS11305	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
STho1984_RS11310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
STho1984_RS11315	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
STho1984_RS11325	COG3005	denitrification pathway
STho1984_RS11330	COG3043	anaerobic respiration
STho1984_RS11335	COG0348	domain, Protein
STho1984_RS11340	COG0437	4 iron, 4 sulfur cluster binding
STho1984_RS11350	COG3062	negative regulation of establishment of protein localization
STho1984_RS11355	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
STho1984_RS11355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
STho1984_RS11365	COG4615	Cyclic peptide transporter
STho1984_RS11390	COG2198	Histidine kinase
STho1984_RS11390	COG0642	Histidine kinase
STho1984_RS11410	COG4948	Mandelate Racemase Muconate Lactonizing
STho1984_RS11440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
STho1984_RS11445	COG2814	Major facilitator Superfamily
STho1984_RS11450	COG0583	DNA-binding transcription factor activity
STho1984_RS11455	COG0584	glycerophosphoryl diester phosphodiesterase
STho1984_RS11460	COG2271	Major facilitator Superfamily
STho1984_RS11465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
STho1984_RS11475	COG0247	lactate metabolic process
STho1984_RS11495	COG2271	Major facilitator Superfamily
STho1984_RS11505	COG1414	Transcriptional regulator
STho1984_RS11595	COG1169	isochorismate synthase
STho1984_RS11600	COG4575	ribosome binding
STho1984_RS11605	COG2153	protein acetylation
STho1984_RS11615	COG0835	chemotaxis
STho1984_RS11615	COG0784	Response regulator, receiver
STho1984_RS11620	COG2304	oxidoreductase activity
STho1984_RS11630	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
STho1984_RS11635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
STho1984_RS11645	COG0839	Belongs to the complex I subunit 6 family
STho1984_RS11695	COG0583	DNA-binding transcription factor activity
STho1984_RS11705	COG0436	Aminotransferase
STho1984_RS11715	COG0490	domain, Protein
STho1984_RS11715	COG0471	metal ion transport
STho1984_RS11720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STho1984_RS11745	COG1288	antiporter activity
STho1984_RS11750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
STho1984_RS11755	COG3959	Transketolase, thiamine diphosphate binding domain
STho1984_RS11760	COG3037	sugar-specific permease SgaT UlaA
STho1984_RS11770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS11780	COG1609	Transcriptional regulator
STho1984_RS11790	COG0622	Phosphoesterase
STho1984_RS11795	COG0625	glutathione transferase activity
STho1984_RS11800	COG0625	glutathione transferase activity
STho1984_RS11805	COG1090	epimerase
STho1984_RS11840	COG0833	amino acid
STho1984_RS11845	COG3457	Alanine racemase
STho1984_RS11850	COG0531	amino acid
STho1984_RS11860	COG3829	transcription factor binding
STho1984_RS11865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
STho1984_RS11870	COG1286	toxin biosynthetic process
STho1984_RS11875	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
STho1984_RS11880	COG0285	dihydrofolate synthase activity
STho1984_RS11890	COG0586	Pfam SNARE associated Golgi protein
STho1984_RS11900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STho1984_RS11925	COG3423	Transcriptional regulator
STho1984_RS11945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STho1984_RS11960	COG3101	peptidyl-lysine hydroxylation
STho1984_RS11965	COG0730	response to heat
STho1984_RS11990	COG2062	phosphohistidine phosphatase, SixA
STho1984_RS12005	COG3691	Protein conserved in bacteria
STho1984_RS12020	COG2116	formate transmembrane transporter activity
STho1984_RS12065	COG1560	Kdo2-lipid A biosynthetic process
STho1984_RS12070	COG0436	Aminotransferase
STho1984_RS12085	COG3961	Belongs to the TPP enzyme family
STho1984_RS12090	COG0667	Aldo Keto reductase
STho1984_RS12105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
STho1984_RS12110	COG2199	diguanylate cyclase activity
STho1984_RS12110	COG2200	EAL domain
STho1984_RS12125	COG3415	Transposase
STho1984_RS12130	COG3415	Transposase
STho1984_RS12160	COG0583	DNA-binding transcription factor activity
STho1984_RS12170	COG2211	Major facilitator Superfamily
STho1984_RS12175	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
STho1984_RS12185	COG0583	DNA-binding transcription factor activity
STho1984_RS12190	COG0385	Bile acid
STho1984_RS12195	COG3530	Putative quorum-sensing-regulated virulence factor
STho1984_RS12225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS12280	COG4208	sulfate ABC transporter
STho1984_RS12300	COG2837	iron assimilation
STho1984_RS12430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
STho1984_RS12440	COG5342	invasion associated locus B
STho1984_RS12455	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
STho1984_RS12455	COG0493	'glutamate synthase
STho1984_RS12460	COG3850	Histidine kinase
STho1984_RS12465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
STho1984_RS12470	COG1393	Belongs to the ArsC family
STho1984_RS12490	COG2321	neutral zinc metallopeptidase
STho1984_RS12500	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
STho1984_RS12505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
STho1984_RS12510	COG2716	regulation of RNA biosynthetic process
STho1984_RS12515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
STho1984_RS12520	COG1929	Belongs to the glycerate kinase type-1 family
STho1984_RS12525	COG2610	gluconate transmembrane transporter activity
STho1984_RS12530	COG3835	regulator
STho1984_RS12535	COG0628	permease
STho1984_RS12545	COG1393	Belongs to the ArsC family
STho1984_RS12555	COG2233	PERMEase
STho1984_RS12570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
STho1984_RS12585	COG2200	EAL domain
STho1984_RS12610	COG2801	Transposase and inactivated derivatives
STho1984_RS12620	COG0516	GMP reductase activity
STho1984_RS12620	COG0517	IMP dehydrogenase activity
STho1984_RS12660	COG1645	bacterial-type flagellum-dependent swarming motility
STho1984_RS12675	COG2976	Protein conserved in bacteria
STho1984_RS12715	COG0437	4 iron, 4 sulfur cluster binding
STho1984_RS12720	COG0243	molybdopterin cofactor binding
STho1984_RS12725	COG4953	penicillin-binding protein 1C
STho1984_RS12730	COG2373	Large extracellular alpha-helical protein
STho1984_RS12735	COG2897	thiosulfate sulfurtransferase activity
STho1984_RS12755	COG2975	iron-sulfur cluster assembly
STho1984_RS12760	COG0633	Ferredoxin
STho1984_RS12780	COG0822	iron-sulfur transferase activity
STho1984_RS12825	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
STho1984_RS12835	COG3711	transcriptional antiterminator
STho1984_RS12840	COG2814	Major facilitator Superfamily
STho1984_RS12850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
STho1984_RS12850	COG1017	nitric oxide dioxygenase activity
STho1984_RS12855	COG3710	Transcriptional regulator
STho1984_RS12860	COG0531	amino acid
STho1984_RS12870	COG3104	oligopeptide transport
STho1984_RS12875	COG0347	Belongs to the P(II) protein family
STho1984_RS12880	COG2204	response regulator
STho1984_RS12885	COG3170	Tfp pilus assembly protein FimV
STho1984_RS12890	COG2205	protein histidine kinase activity
STho1984_RS12915	COG0560	Phosphoserine phosphatase
STho1984_RS12920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STho1984_RS12920	COG1263	PTS System
STho1984_RS12930	COG1737	Transcriptional regulator
STho1984_RS12935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
STho1984_RS12940	COG2223	nitrite transmembrane transporter activity
STho1984_RS12945	COG0583	DNA-binding transcription factor activity
STho1984_RS12950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
STho1984_RS12990	COG3086	response to oxidative stress
STho1984_RS13020	COG0513	Belongs to the DEAD box helicase family
STho1984_RS13025	COG0583	DNA-binding transcription factor activity
STho1984_RS13045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STho1984_RS13050	COG3118	belongs to the thioredoxin family
STho1984_RS13055	COG3148	PFAM DTW domain containing protein
STho1984_RS13065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STho1984_RS13070	COG5544	Lipoprotein
STho1984_RS13075	COG0477	Major facilitator Superfamily
STho1984_RS13105	COG0542	response to heat
STho1984_RS13120	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
STho1984_RS13125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
STho1984_RS13130	COG1605	Chorismate mutase
STho1984_RS13130	COG0077	Prephenate dehydratase
STho1984_RS13140	COG1605	Chorismate mutase
STho1984_RS13140	COG0287	Prephenate dehydrogenase
STho1984_RS13155	COG2199	diguanylate cyclase activity
STho1984_RS13180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STho1984_RS13185	COG4137	Cytochrome C assembly protein
STho1984_RS13190	COG4536	flavin adenine dinucleotide binding
STho1984_RS13210	COG0497	DNA recombination
STho1984_RS13225	COG2867	negative regulation of translational initiation
STho1984_RS13250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STho1984_RS13255	COG0582	viral genome integration into host DNA
STho1984_RS13320	COG2819	hydrolase of the alpha beta superfamily
STho1984_RS13340	COG2990	Protein conserved in bacteria
STho1984_RS13355	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
STho1984_RS13395	COG0579	oxidoreductase
STho1984_RS13400	COG1012	belongs to the aldehyde dehydrogenase family
STho1984_RS13405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
STho1984_RS13410	COG1113	amino acid transport
STho1984_RS13415	COG1802	Transcriptional regulator
STho1984_RS13420	COG1652	LysM domain
STho1984_RS13425	COG0401	homolog of Blt101
STho1984_RS13430	COG0640	Transcriptional regulator
STho1984_RS13435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
STho1984_RS13460	COG4575	ribosome binding
STho1984_RS13470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
STho1984_RS13515	COG2814	Major facilitator Superfamily
STho1984_RS13520	COG1846	Transcriptional regulator
STho1984_RS13525	COG1566	PFAM secretion protein HlyD family protein
STho1984_RS13530	COG2814	Major facilitator Superfamily
STho1984_RS13550	COG1238	metal cluster binding
STho1984_RS13555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STho1984_RS13585	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
STho1984_RS13605	COG1546	Belongs to the CinA family
STho1984_RS13610	COG2951	lytic endotransglycosylase activity
STho1984_RS13615	COG3730	PTS system glucitol sorbitol-specific
STho1984_RS13620	COG3732	PTS system glucitol sorbitol-specific
STho1984_RS13625	COG3731	PTS system glucitol sorbitol-specific IIA component
STho1984_RS13630	COG1028	Short-chain dehydrogenase reductase Sdr
STho1984_RS13635	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS13645	COG1349	DNA-binding transcription factor activity
STho1984_RS13670	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
STho1984_RS13675	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
STho1984_RS13685	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
STho1984_RS13695	COG3260	NADH ubiquinone oxidoreductase 20
STho1984_RS13700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
STho1984_RS13705	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
STho1984_RS13705	COG3261	NADH dehydrogenase
STho1984_RS13710	COG0650	Formate hydrogenlyase subunit 4
STho1984_RS13715	COG0651	ATP synthesis coupled electron transport
STho1984_RS13720	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
STho1984_RS13735	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
STho1984_RS13740	COG0298	carbon dioxide binding
STho1984_RS13745	COG0409	Hydrogenase expression formation protein
STho1984_RS13750	COG0309	Hydrogenase expression formation protein (HypE)
STho1984_RS13770	COG1121	(ABC) transporter
STho1984_RS13775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STho1984_RS13780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STho1984_RS13865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STho1984_RS13955	COG2207	Transcriptional regulator
STho1984_RS14025	COG0477	Major facilitator Superfamily
STho1984_RS14035	COG2610	gluconate transmembrane transporter activity
STho1984_RS14040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
STho1984_RS14045	COG3622	Belongs to the hyi family
STho1984_RS14050	COG0235	Class ii aldolase
STho1984_RS14060	COG2084	Dehydrogenase
STho1984_RS14065	COG1349	DNA-binding transcription factor activity
STho1984_RS14075	COG0163	prenyltransferase activity
STho1984_RS14080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
STho1984_RS14150	COG2234	aminopeptidase activity
STho1984_RS14155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
STho1984_RS14160	COG1518	maintenance of DNA repeat elements
STho1984_RS14175	COG1857	crispr-associated protein
STho1984_RS14190	COG1203	CRISPR-associated helicase, Cas3
STho1984_RS14215	COG0720	synthase
STho1984_RS14225	COG0602	queuosine metabolic process
STho1984_RS14240	COG3956	TIGRFAM MazG family protein
STho1984_RS14245	COG3539	Fimbrial protein
STho1984_RS14250	COG3188	usher protein
STho1984_RS14255	COG3121	Chaperone
STho1984_RS14260	COG3539	Fimbrial protein
STho1984_RS14295	COG3609	addiction module antidote protein, CC2985 family
STho1984_RS14300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
STho1984_RS14310	COG3850	Histidine kinase
STho1984_RS14310	COG4999	Histidine kinase
STho1984_RS14310	COG2205	protein histidine kinase activity
STho1984_RS14310	COG3437	response regulator, receiver
STho1984_RS14315	COG1929	Belongs to the glycerate kinase type-1 family
STho1984_RS14320	COG4948	Mandelate Racemase Muconate Lactonizing
STho1984_RS14325	COG4948	Mandelate Racemase Muconate Lactonizing
STho1984_RS14330	COG2271	Major facilitator Superfamily
STho1984_RS14335	COG0716	FMN binding
STho1984_RS14345	COG3098	single-species biofilm formation
STho1984_RS14360	COG1611	Belongs to the LOG family
STho1984_RS14365	COG0814	amino acid
STho1984_RS14370	COG1760	l-serine dehydratase
STho1984_RS14380	COG1454	alcohol dehydrogenase
STho1984_RS14385	COG0235	Class ii aldolase
STho1984_RS14390	COG0738	Major facilitator superfamily
STho1984_RS14410	COG1349	DNA-binding transcription factor activity
STho1984_RS14420	COG2363	Small membrane protein
STho1984_RS14425	COG0583	DNA-binding transcription factor activity
STho1984_RS14435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
STho1984_RS14440	COG2166	iron-sulfur cluster assembly
STho1984_RS14445	COG2962	Rard protein
STho1984_RS14450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
STho1984_RS14455	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
STho1984_RS14470	COG0860	N-Acetylmuramoyl-L-alanine amidase
STho1984_RS14480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
STho1984_RS14485	COG1074	ATP-dependent DNA helicase activity
STho1984_RS14490	COG1025	Belongs to the peptidase M16 family
STho1984_RS14495	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
STho1984_RS14500	COG4967	type IV pilus modification protein PilV
STho1984_RS14510	COG4795	General secretion pathway protein
STho1984_RS14515	COG2165	general secretion pathway protein
STho1984_RS14555	COG0861	Integral membrane protein TerC family
STho1984_RS14565	COG0667	Aldo Keto reductase
STho1984_RS14585	COG1609	Transcriptional regulator
STho1984_RS14595	COG0583	DNA-binding transcription factor activity
STho1984_RS14600	COG1794	racemase activity, acting on amino acids and derivatives
STho1984_RS14605	COG2814	Major facilitator Superfamily
STho1984_RS14610	COG1028	Short-chain dehydrogenase reductase Sdr
STho1984_RS14620	COG0183	Belongs to the thiolase family
STho1984_RS14635	COG0814	amino acid
STho1984_RS14670	COG3188	usher protein
STho1984_RS14715	COG4942	peptidase
STho1984_RS14775	COG1272	protein, Hemolysin III
STho1984_RS14785	COG2723	6-phospho-beta-galactosidase activity
STho1984_RS14810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
STho1984_RS14815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
STho1984_RS14820	COG0006	proline dipeptidase activity
STho1984_RS14835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STho1984_RS14840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
STho1984_RS14855	COG2968	Membrane
STho1984_RS14865	COG0668	transmembrane transport
STho1984_RS14870	COG0191	fructose-bisphosphate aldolase activity
STho1984_RS14900	COG1122	ATPase activity
STho1984_RS14905	COG1122	ATPase activity
STho1984_RS14910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
STho1984_RS14915	COG0501	Belongs to the peptidase M48B family
STho1984_RS14925	COG2267	carboxylic ester hydrolase activity
STho1984_RS14930	COG2731	YhcH YjgK YiaL family protein
STho1984_RS14935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
STho1984_RS14940	COG1063	alcohol dehydrogenase
STho1984_RS14945	COG0246	Mannitol dehydrogenase
STho1984_RS14950	COG4948	Mandelate Racemase Muconate Lactonizing
STho1984_RS14955	COG2186	Transcriptional regulator
STho1984_RS14965	COG1166	arginine decarboxylase activity
STho1984_RS14985	COG2814	Major facilitator Superfamily
STho1984_RS14995	COG2356	endonuclease I
STho1984_RS15000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
STho1984_RS15025	COG2805	Type II/IV secretion system protein
STho1984_RS15030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STho1984_RS15035	COG0762	integral membrane protein
STho1984_RS15050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
STho1984_RS15060	COG0252	asparaginase activity
STho1984_RS15070	COG3171	Protein conserved in bacteria
STho1984_RS15095	COG2211	Major facilitator Superfamily
STho1984_RS15100	COG1982	Orn Lys Arg decarboxylase major
STho1984_RS15110	COG1811	Na channel or pump
STho1984_RS15125	COG0427	acetyl-CoA hydrolase
STho1984_RS15130	COG2030	dehydratase
STho1984_RS15135	COG2301	Belongs to the HpcH HpaI aldolase family
STho1984_RS15165	COG0531	amino acid
STho1984_RS15175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
STho1984_RS15180	COG1012	belongs to the aldehyde dehydrogenase family
STho1984_RS15205	COG2271	Major facilitator Superfamily
STho1984_RS15215	COG0246	Mannitol dehydrogenase
STho1984_RS15230	COG0754	glutathionylspermidine amidase activity
STho1984_RS15235	COG0625	glutathione transferase activity
STho1984_RS15245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
STho1984_RS15250	COG0298	carbon dioxide binding
STho1984_RS15260	COG1773	rubredoxin
STho1984_RS15265	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
STho1984_RS15270	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
STho1984_RS15275	COG5557	Pfam Polysulphide reductase, NrfD
STho1984_RS15280	COG0437	4 iron, 4 sulfur cluster binding
STho1984_RS15285	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
STho1984_RS15295	COG0840	transmembrane signaling receptor activity
STho1984_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
STho1984_RS15325	COG0848	biopolymer transport protein
STho1984_RS15350	COG2207	Transcriptional regulator
STho1984_RS15355	COG1979	alcohol dehydrogenase
STho1984_RS15365	COG0471	metal ion transport
STho1984_RS15415	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
STho1984_RS15420	COG3111	PFAM Bacterial OB fold (BOF) protein
STho1984_RS15430	COG0642	Histidine kinase
STho1984_RS15435	COG2249	NAD(P)H dehydrogenase (quinone) activity
STho1984_RS15440	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
STho1984_RS15450	COG3150	esterase
STho1984_RS15455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
STho1984_RS15460	COG3151	Protein conserved in bacteria
STho1984_RS15465	COG0494	nUDIX hydrolase
STho1984_RS15480	COG0754	glutathionylspermidine amidase activity
STho1984_RS15485	COG3384	dioxygenase
STho1984_RS15530	COG1585	Membrane protein implicated in regulation of membrane protease activity
STho1984_RS15535	COG2268	Band 7 protein
STho1984_RS15550	COG3025	triphosphatase activity
STho1984_RS15555	COG4991	sh3 domain protein
STho1984_RS15570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
STho1984_RS15590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
STho1984_RS15615	COG2375	cellular response to nickel ion
STho1984_RS15620	COG1695	Transcriptional regulator
STho1984_RS15625	COG0840	transmembrane signaling receptor activity
STho1984_RS15630	COG0840	transmembrane signaling receptor activity
STho1984_RS15640	COG0446	pyridine nucleotide-disulphide oxidoreductase
STho1984_RS15640	COG1902	pentaerythritol trinitrate reductase activity
STho1984_RS15650	COG1451	nucleotide metabolic process
STho1984_RS15655	COG2949	membrane
STho1984_RS15660	COG0673	inositol 2-dehydrogenase activity
STho1984_RS15675	COG0586	Pfam SNARE associated Golgi protein
STho1984_RS15685	COG1422	Protein of unknown function (DUF1090)
STho1984_RS15690	COG4575	ribosome binding
STho1984_RS15695	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
STho1984_RS15705	COG2259	Doxx family
STho1984_RS15710	COG0435	Glutathione S-transferase
STho1984_RS15715	COG3152	Membrane
STho1984_RS15720	COG0583	DNA-binding transcription factor activity
STho1984_RS15725	COG1741	Belongs to the pirin family
STho1984_RS15740	COG0814	amino acid
STho1984_RS15745	COG1760	l-serine dehydratase
STho1984_RS15750	COG1882	Formate acetyltransferase
STho1984_RS15770	COG0583	DNA-binding transcription factor activity
STho1984_RS15780	COG1929	Belongs to the glycerate kinase type-1 family
STho1984_RS15785	COG2084	Dehydrogenase
STho1984_RS15795	COG2721	sulfolactate sulfo-lyase activity
STho1984_RS15800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS15805	COG1349	DNA-binding transcription factor activity
STho1984_RS15815	COG1105	Belongs to the carbohydrate kinase PfkB family
STho1984_RS15820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS15820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STho1984_RS15820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STho1984_RS15835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS15840	COG3414	Phosphotransferase system galactitol-specific IIB component
STho1984_RS15845	COG3775	system Galactitol-specific IIC component
STho1984_RS15850	COG1063	alcohol dehydrogenase
STho1984_RS15860	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
STho1984_RS15865	COG3107	peptidoglycan biosynthetic process
STho1984_RS15880	COG2823	Periplasmic or secreted lipoprotein
STho1984_RS15885	COG0702	epimerase
STho1984_RS15890	COG0693	protein deglycase activity
STho1984_RS15905	COG3153	acetyltransferase
STho1984_RS15910	COG3154	lipid carrier protein
STho1984_RS15915	COG0826	peptidase U32
STho1984_RS15920	COG0826	peptidase U32
STho1984_RS15925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
STho1984_RS15930	COG3034	peptidoglycan biosynthetic process
STho1984_RS15940	COG0814	amino acid
STho1984_RS15945	COG0513	Belongs to the DEAD box helicase family
STho1984_RS15995	COG0137	argininosuccinate synthase activity
STho1984_RS16005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
STho1984_RS16015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
STho1984_RS16030	COG1534	Rna-binding protein
STho1984_RS16045	COG2027	D-alanyl-D-alanine carboxypeptidase
STho1984_RS16055	COG0697	spore germination
STho1984_RS16070	COG0142	geranyltranstransferase activity
STho1984_RS16075	COG3423	Transcriptional regulator
STho1984_RS16085	COG5007	Belongs to the BolA IbaG family
STho1984_RS16090	COG3113	response to antibiotic
STho1984_RS16095	COG2854	intermembrane phospholipid transfer
STho1984_RS16100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
STho1984_RS16105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
STho1984_RS16110	COG1127	ABC transporter
STho1984_RS16115	COG0530	calcium, potassium:sodium antiporter activity
STho1984_RS16130	COG3117	lipopolysaccharide transmembrane transporter activity
STho1984_RS16135	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
STho1984_RS16140	COG1137	ATPase activity
STho1984_RS16165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS16170	COG0515	serine threonine protein kinase
STho1984_RS16180	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
STho1984_RS16185	COG0784	Response regulator, receiver
STho1984_RS16185	COG2198	Histidine kinase
STho1984_RS16185	COG5002	protein histidine kinase activity
STho1984_RS16190	COG1242	4 iron, 4 sulfur cluster binding
STho1984_RS16200	COG0070	glutamate synthase
STho1984_RS16200	COG0069	glutamate synthase activity
STho1984_RS16200	COG0067	glutamate synthase
STho1984_RS16205	COG0493	'glutamate synthase
STho1984_RS16210	COG4804	nuclease activity
STho1984_RS16215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
STho1984_RS16220	COG0402	S-adenosylhomocysteine deaminase activity
STho1984_RS16225	COG2731	YhcH YjgK YiaL family protein
STho1984_RS16255	COG2969	positive regulation of protein catabolic process
STho1984_RS16260	COG0625	glutathione transferase activity
STho1984_RS16280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
STho1984_RS16285	COG3105	Protein conserved in bacteria
STho1984_RS16290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STho1984_RS16320	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
STho1984_RS16325	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
STho1984_RS16330	COG0471	metal ion transport
STho1984_RS16340	COG2188	Transcriptional regulator
STho1984_RS16365	COG2732	(Barnase) inhibitor
STho1984_RS16385	COG0583	DNA-binding transcription factor activity
STho1984_RS16390	COG0312	modulator of DNA gyrase
STho1984_RS16395	COG3164	Protein of unknown function
STho1984_RS16410	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
STho1984_RS16415	COG1792	Involved in formation and maintenance of cell shape
STho1984_RS16420	COG1077	Cell shape determining protein MreB Mrl
STho1984_RS16430	COG2200	EAL domain
STho1984_RS16430	COG2199	diguanylate cyclase activity
STho1984_RS16435	COG0604	alcohol dehydrogenase
STho1984_RS16450	COG0511	ligase activity, forming carbon-carbon bonds
STho1984_RS16455	COG0439	Biotin carboxylase
STho1984_RS16460	COG3924	membrane
STho1984_RS16465	COG4145	pantothenate transmembrane transporter activity
STho1984_RS16485	COG2189	Belongs to the N(4) N(6)-methyltransferase family
STho1984_RS16500	COG1309	transcriptional regulator
STho1984_RS16505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STho1984_RS16510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
STho1984_RS16555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
STho1984_RS16575	COG0551	DNA topoisomerase type I activity
STho1984_RS16615	COG3036	rescue of stalled ribosome
STho1984_RS16620	COG0789	Transcriptional regulator
STho1984_RS16660	COG0201	protein transport
STho1984_RS16740	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
STho1984_RS16765	COG0051	transcription antitermination factor activity, RNA binding
STho1984_RS16820	COG2964	Protein conserved in bacteria
STho1984_RS16825	COG0545	Peptidyl-prolyl cis-trans isomerase
STho1984_RS16835	COG1047	Peptidyl-prolyl cis-trans
STho1984_RS16840	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
STho1984_RS16855	COG0488	(ABC) transporter
STho1984_RS16870	COG0429	hydrolase of the alpha beta-hydrolase fold
STho1984_RS16880	COG3954	Phosphoribulokinase
STho1984_RS16885	COG1765	OsmC-like protein
STho1984_RS16895	COG1289	transmembrane transporter activity
STho1984_RS16930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
STho1984_RS16970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
STho1984_RS16975	COG0338	D12 class N6 adenine-specific DNA methyltransferase
STho1984_RS16980	COG3266	domain, Protein
STho1984_RS16995	COG4796	Type ii and iii secretion system protein
STho1984_RS17010	COG3166	PFAM Fimbrial assembly family protein
STho1984_RS17015	COG4972	Pilus assembly protein
STho1984_RS17020	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
STho1984_RS17025	COG0494	nUDIX hydrolase
STho1984_RS17035	COG1011	Hydrolase
STho1984_RS17040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
STho1984_RS17050	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
STho1984_RS17070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
STho1984_RS17075	COG2183	response to ionizing radiation
STho1984_RS17080	COG1918	ferrous iron import across plasma membrane
STho1984_RS17095	COG5464	transposase or invertase
STho1984_RS17115	COG2610	gluconate transmembrane transporter activity
STho1984_RS17120	COG1640	4-alpha-glucanotransferase
STho1984_RS17125	COG0058	SHG alpha-glucan phosphorylase activity
STho1984_RS17145	COG1690	Belongs to the RtcB family
STho1984_RS17155	COG4650	regulator
STho1984_RS17160	COG1349	DNA-binding transcription factor activity
STho1984_RS17175	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
STho1984_RS17190	COG0371	Dehydrogenase
STho1984_RS17200	COG0129	dihydroxy-acid dehydratase activity
STho1984_RS17205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
STho1984_RS17210	COG1414	Transcriptional regulator
STho1984_RS17215	COG0058	SHG alpha-glucan phosphorylase activity
STho1984_RS17245	COG2610	gluconate transmembrane transporter activity
STho1984_RS17250	COG3265	gluconokinase activity
STho1984_RS17255	COG1609	Transcriptional regulator
STho1984_RS17260	COG1741	Belongs to the pirin family
STho1984_RS17265	COG0673	inositol 2-dehydrogenase activity
STho1984_RS17270	COG1247	-acetyltransferase
STho1984_RS17275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS17290	COG1735	metal-dependent hydrolase with the TIM-barrel fold
STho1984_RS17295	COG0405	Gamma-glutamyltransferase
STho1984_RS17305	COG0584	glycerophosphoryl diester phosphodiesterase
STho1984_RS17385	COG2177	Part of the ABC transporter FtsEX involved in
STho1984_RS17390	COG2884	Cell division ATP-binding protein ftsE
STho1984_RS17395	COG0552	protein localization to endoplasmic reticulum
STho1984_RS17400	COG0742	ribosomal rna small subunit methyltransferase
STho1984_RS17405	COG3776	membrane
STho1984_RS17415	COG3714	YhhN family
STho1984_RS17435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
STho1984_RS17450	COG0628	permease
STho1984_RS17455	COG2091	lysine biosynthetic process via aminoadipic acid
STho1984_RS17465	COG0842	Transport permease protein
STho1984_RS17470	COG0842	Transport permease protein
STho1984_RS17470	COG1129	ABC transporter
STho1984_RS17475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STho1984_RS17480	COG2081	HI0933 family
STho1984_RS17485	COG0306	phosphate transporter
STho1984_RS17515	COG0671	phosphoesterase, PA-phosphatase related
STho1984_RS17520	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
STho1984_RS17525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STho1984_RS17535	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
STho1984_RS17540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS17545	COG2222	sugar isomerase
STho1984_RS17550	COG2188	Transcriptional regulator
STho1984_RS17570	COG2197	response regulator
STho1984_RS17575	COG0583	DNA-binding transcription factor activity
STho1984_RS17580	COG1295	ribonuclease BN
STho1984_RS17585	COG0477	Major facilitator Superfamily
STho1984_RS17590	COG2982	Protein involved in outer membrane biogenesis
STho1984_RS17595	COG2200	EAL domain
STho1984_RS17600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS17615	COG2199	diguanylate cyclase activity
STho1984_RS17615	COG2200	EAL domain
STho1984_RS17670	COG2873	o-acetylhomoserine
STho1984_RS17675	COG0814	amino acid
STho1984_RS17680	COG4608	Belongs to the ABC transporter superfamily
STho1984_RS17685	COG0444	Belongs to the ABC transporter superfamily
STho1984_RS17690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STho1984_RS17695	COG0601	transmembrane transport
STho1984_RS17700	COG0747	negative chemotaxis
STho1984_RS17715	COG1609	Transcriptional regulator
STho1984_RS17760	COG5571	outer membrane autotransporter
STho1984_RS17765	COG2818	Glycosylase
STho1984_RS17770	COG0456	acetyltransferase
STho1984_RS17775	COG0243	molybdopterin cofactor binding
STho1984_RS17780	COG2885	chlorophyll binding
STho1984_RS17795	COG2944	sequence-specific DNA binding
STho1984_RS17800	COG1278	Cold shock
STho1984_RS17825	COG2801	Transposase and inactivated derivatives
STho1984_RS17845	COG3274	enterobacterial common antigen metabolic process
STho1984_RS17850	COG4682	membrane
STho1984_RS17855	COG1070	Carbohydrate kinase
STho1984_RS17865	COG2207	Transcriptional regulator
STho1984_RS17865	COG1609	Transcriptional regulator
STho1984_RS17870	COG2992	FlgJ-related protein
STho1984_RS17880	COG0366	Alpha amylase catalytic
STho1984_RS17885	COG3977	Valine--pyruvate aminotransferase
STho1984_RS17890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
STho1984_RS17895	COG1414	Transcriptional regulator
STho1984_RS17905	COG2731	YhcH YjgK YiaL family protein
STho1984_RS17915	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
STho1984_RS17920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
STho1984_RS17925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
STho1984_RS17930	COG1070	Carbohydrate kinase
STho1984_RS17935	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
STho1984_RS17940	COG3623	hexulose-6-phosphate isomerase
STho1984_RS17945	COG0235	Class ii aldolase
STho1984_RS17960	COG1012	belongs to the aldehyde dehydrogenase family
STho1984_RS17965	COG1940	carbohydrate kinase activity
STho1984_RS17970	COG3276	selenocysteine insertion sequence binding
STho1984_RS17980	COG0625	glutathione transferase activity
STho1984_RS17985	COG1566	PFAM secretion protein HlyD family protein
STho1984_RS17995	COG2213	PTS system mannitol-specific
STho1984_RS17995	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS18005	COG3722	fumarate hydratase activity
STho1984_RS18035	COG2186	Transcriptional regulator
STho1984_RS18045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
STho1984_RS18050	COG1609	Transcriptional regulator
STho1984_RS18060	COG2271	Major facilitator Superfamily
STho1984_RS18080	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
STho1984_RS18085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
STho1984_RS18095	COG4942	peptidase
STho1984_RS18100	COG2861	carbohydrate metabolic process
STho1984_RS18105	COG1216	Glycosyl transferase, family 2
STho1984_RS18180	COG0438	transferase activity, transferring glycosyl groups
STho1984_RS18185	COG0859	PFAM glycosyl transferase family 9
STho1984_RS18190	COG1519	Transferase
STho1984_RS18220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STho1984_RS18245	COG1561	YicC-like family, N-terminal region
STho1984_RS18250	COG0583	DNA-binding transcription factor activity
STho1984_RS18260	COG2860	membrane
STho1984_RS18280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
STho1984_RS18285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STho1984_RS18290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STho1984_RS18295	COG0786	glutamate:sodium symporter activity
STho1984_RS18300	COG2233	PERMEase
STho1984_RS18305	COG2982	Protein involved in outer membrane biogenesis
STho1984_RS18310	COG1501	Belongs to the glycosyl hydrolase 31 family
STho1984_RS18315	COG2211	Major facilitator Superfamily
STho1984_RS18325	COG2771	luxR family
STho1984_RS18340	COG3710	Transcriptional regulator
STho1984_RS18345	COG1335	isochorismatase
STho1984_RS18370	COG5464	transposase or invertase
STho1984_RS18385	COG3716	PTS system mannose fructose sorbose family IID component
STho1984_RS18390	COG3715	PTS system
STho1984_RS18395	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS18395	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STho1984_RS18415	COG2723	6-phospho-beta-galactosidase activity
STho1984_RS18460	COG3775	system Galactitol-specific IIC component
STho1984_RS18465	COG3414	Phosphotransferase system galactitol-specific IIB component
STho1984_RS18470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS18470	COG3711	transcriptional antiterminator
STho1984_RS18475	COG2188	Transcriptional regulator
STho1984_RS18510	COG0738	Major facilitator superfamily
STho1984_RS18520	COG1349	DNA-binding transcription factor activity
STho1984_RS18525	COG0440	acetolactate synthase activity
STho1984_RS18530	COG0028	Belongs to the TPP enzyme family
STho1984_RS18550	COG2814	Major facilitator Superfamily
STho1984_RS18560	COG0583	DNA-binding transcription factor activity
STho1984_RS18565	COG2610	gluconate transmembrane transporter activity
STho1984_RS18575	COG0641	radical SAM
STho1984_RS18585	COG2149	membrane
STho1984_RS18605	COG5645	(Lipo)protein
STho1984_RS18610	COG0823	Involved in the tonB-independent uptake of proteins
STho1984_RS18615	COG4235	cytochrome complex assembly
STho1984_RS18615	COG3088	subunit of a heme lyase
STho1984_RS18620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STho1984_RS18625	COG1138	Cytochrome C-type biogenesis protein
STho1984_RS18635	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
STho1984_RS18640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
STho1984_RS18645	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
STho1984_RS18655	COG1858	cytochrome C peroxidase
STho1984_RS18670	COG3005	denitrification pathway
STho1984_RS18675	COG0745	RESPONSE REGULATOR receiver
STho1984_RS18680	COG1879	ABC-type sugar transport system periplasmic component
STho1984_RS18685	COG2205	protein histidine kinase activity
STho1984_RS18685	COG2198	Histidine kinase
STho1984_RS18685	COG0784	Response regulator, receiver
STho1984_RS18690	COG2271	Major facilitator Superfamily
STho1984_RS18700	COG0800	Aldolase
STho1984_RS18705	COG3734	2-keto-3-deoxy-galactonokinase
STho1984_RS18710	COG2186	Transcriptional regulator
STho1984_RS18715	COG0561	phosphatase activity
STho1984_RS18720	COG2271	Major facilitator Superfamily
STho1984_RS18725	COG4948	Mandelate Racemase Muconate Lactonizing
STho1984_RS18790	COG2091	lysine biosynthetic process via aminoadipic acid
STho1984_RS18795	COG0431	NADPH-dependent FMN reductase
STho1984_RS18800	COG2252	PERMEase
STho1984_RS18805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STho1984_RS18810	COG0704	Plays a role in the regulation of phosphate uptake
STho1984_RS18820	COG0581	inorganic phosphate transmembrane transporter activity
STho1984_RS18825	COG0573	inorganic phosphate transmembrane transporter activity
STho1984_RS18830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
STho1984_RS18835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STho1984_RS18835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STho1984_RS18835	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
STho1984_RS18840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
STho1984_RS18845	COG4533	DNA binding
STho1984_RS18905	COG3312	ion transport
STho1984_RS18920	COG0716	FMN binding
STho1984_RS18925	COG1522	sequence-specific DNA binding
STho1984_RS18960	COG1172	Belongs to the binding-protein-dependent transport system permease family
STho1984_RS18970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS18975	COG1609	Transcriptional regulator
STho1984_RS18980	COG0477	Major facilitator Superfamily
STho1984_RS18985	COG2186	Transcriptional regulator
STho1984_RS19045	COG3978	acetolactate synthase activity
STho1984_RS19110	COG3118	belongs to the thioredoxin family
STho1984_RS19125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STho1984_RS19140	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
STho1984_RS19145	COG1088	dTDP-glucose 4,6-dehydratase activity
STho1984_RS19150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
STho1984_RS19155	COG0456	acetyltransferase
STho1984_RS19160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
STho1984_RS19165	COG2244	polysaccharide biosynthetic process
STho1984_RS19210	COG3071	HemY protein
STho1984_RS19215	COG2959	enzyme of heme biosynthesis
STho1984_RS19265	COG1011	Hydrolase
STho1984_RS19310	COG1280	lysine exporter protein (LysE YggA)
STho1984_RS19315	COG1280	lysine exporter protein (LysE YggA)
STho1984_RS19320	COG2267	carboxylic ester hydrolase activity
STho1984_RS19325	COG0561	phosphatase activity
STho1984_RS19345	COG0641	radical SAM
STho1984_RS19390	COG0805	protein transport
STho1984_RS19435	COG1739	Uncharacterized protein family UPF0029
STho1984_RS19475	COG1763	Mo-molybdopterin cofactor biosynthetic process
STho1984_RS19485	COG3084	Protein conserved in bacteria
STho1984_RS19500	COG0204	Acyl-transferase
STho1984_RS19555	COG0561	phosphatase activity
STho1984_RS19590	COG2211	Major facilitator Superfamily
STho1984_RS19600	COG1501	Belongs to the glycosyl hydrolase 31 family
STho1984_RS19610	COG2017	converts alpha-aldose to the beta-anomer
STho1984_RS19620	COG3684	Belongs to the aldolase LacD family
STho1984_RS19630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS19635	COG1349	DNA-binding transcription factor activity
STho1984_RS19640	COG1011	Hydrolase
STho1984_RS19655	COG0456	acetyltransferase
STho1984_RS19660	COG5499	transcription regulator containing HTH domain
STho1984_RS19665	COG4680	protein conserved in bacteria
STho1984_RS19675	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
STho1984_RS19690	COG2864	formate dehydrogenase
STho1984_RS19695	COG0437	4 iron, 4 sulfur cluster binding
STho1984_RS19700	COG3383	formate dehydrogenase (NAD+) activity
STho1984_RS19700	COG0243	molybdopterin cofactor binding
STho1984_RS19705	COG0243	molybdopterin cofactor binding
STho1984_RS19705	COG3383	formate dehydrogenase (NAD+) activity
STho1984_RS19730	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
STho1984_RS19745	COG1454	alcohol dehydrogenase
STho1984_RS19795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
STho1984_RS19805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
STho1984_RS19810	COG2258	MOSC domain
STho1984_RS19820	COG2205	protein histidine kinase activity
STho1984_RS19825	COG0745	RESPONSE REGULATOR receiver
STho1984_RS19830	COG3678	ATP-independent chaperone mediated protein folding
STho1984_RS19850	COG2134	cdp-diacylglycerol pyrophosphatase
STho1984_RS19855	COG2211	Major facilitator Superfamily
STho1984_RS19860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS19870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
STho1984_RS19885	COG1070	Carbohydrate kinase
STho1984_RS19940	COG3152	Membrane
STho1984_RS19950	COG1494	fructose-1,6-bisphosphatase
STho1984_RS19960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STho1984_RS19975	COG1575	Belongs to the MenA family. Type 1 subfamily
STho1984_RS19990	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
STho1984_RS19995	COG1609	Transcriptional regulator
STho1984_RS20000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
STho1984_RS20025	COG0626	cystathionine gamma-synthase activity
STho1984_RS20030	COG0460	homoserine dehydrogenase
STho1984_RS20030	COG0527	aspartate kinase activity
STho1984_RS20035	COG0668	transmembrane transport
STho1984_RS20050	COG0737	Belongs to the 5'-nucleotidase family
STho1984_RS20065	COG3738	Protein conserved in bacteria
STho1984_RS20070	COG0371	Dehydrogenase
STho1984_RS20080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
STho1984_RS20080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS20080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS20085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STho1984_RS20090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STho1984_RS20095	COG1882	Formate acetyltransferase
STho1984_RS20100	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STho1984_RS20105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STho1984_RS20110	COG2207	Transcriptional regulator
STho1984_RS20145	COG0583	DNA-binding transcription factor activity
STho1984_RS20205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
STho1984_RS20255	COG0250	Participates in transcription elongation, termination and antitermination
STho1984_RS20315	COG2104	thiamine diphosphate biosynthetic process
STho1984_RS20320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
STho1984_RS20385	COG0151	Belongs to the GarS family
STho1984_RS20430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
STho1984_RS20475	COG3122	Protein conserved in bacteria
STho1984_RS20520	COG5301	cellulose 1,4-beta-cellobiosidase activity
STho1984_RS20550	COG2246	polysaccharide biosynthetic process
STho1984_RS20625	COG0527	aspartate kinase activity
STho1984_RS20650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
STho1984_RS20660	COG3833	ABC-type maltose transport systems, permease component
STho1984_RS20705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
STho1984_RS20715	COG0534	Mate efflux family protein
STho1984_RS20730	COG0735	belongs to the Fur family
STho1984_RS20780	COG2315	Protein conserved in bacteria
STho1984_RS20845	COG4943	cyclic-guanylate-specific phosphodiesterase activity
STho1984_RS20865	COG2252	PERMEase
STho1984_RS20870	COG0025	NhaP-type Na H and K H
STho1984_RS20875	COG0583	DNA-binding transcription factor activity
STho1984_RS20880	COG1380	Effector of murein hydrolase LrgA
STho1984_RS20885	COG1346	cytolysis
STho1984_RS20895	COG3162	membrane
STho1984_RS20900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
STho1984_RS20915	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
STho1984_RS20920	COG0437	4 iron, 4 sulfur cluster binding
STho1984_RS20925	COG3301	Polysulphide reductase, NrfD
STho1984_RS20930	COG1138	Cytochrome C-type biogenesis protein
STho1984_RS20935	COG3088	subunit of a heme lyase
STho1984_RS20940	COG4235	cytochrome complex assembly
STho1984_RS20945	COG1301	dicarboxylic acid transport
STho1984_RS20950	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
STho1984_RS20955	COG3383	formate dehydrogenase (NAD+) activity
STho1984_RS20960	COG3383	formate dehydrogenase (NAD+) activity
STho1984_RS20975	COG2764	glyoxalase bleomycin resistance protein dioxygenase
STho1984_RS20980	COG2824	Alkylphosphonate utilization operon protein PhnA
STho1984_RS21005	COG0531	amino acid
STho1984_RS21010	COG2207	Transcriptional regulator
STho1984_RS21020	COG1982	Orn Lys Arg decarboxylase major
STho1984_RS21025	COG2169	Transcriptional regulator
STho1984_RS21040	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
STho1984_RS21040	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
STho1984_RS21045	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
STho1984_RS21055	COG4565	transcriptional regulatory protein
STho1984_RS21060	COG3290	protein histidine kinase activity
STho1984_RS21065	COG0243	molybdopterin cofactor binding
STho1984_RS21070	COG0437	4 iron, 4 sulfur cluster binding
STho1984_RS21075	COG3302	dmso reductase anchor subunit
STho1984_RS21080	COG3381	protein complex oligomerization
STho1984_RS21095	COG1132	(ABC) transporter
STho1984_RS21100	COG2197	response regulator
STho1984_RS21120	COG2801	Transposase and inactivated derivatives
STho1984_RS21140	COG3328	transposase activity
STho1984_RS21145	COG3328	transposase activity
STho1984_RS21160	COG1309	transcriptional regulator
STho1984_RS21175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
STho1984_RS21180	COG1027	Aspartate ammonia-lyase
STho1984_RS21190	COG3030	protein affecting phage T7 exclusion by the F plasmid
STho1984_RS21195	COG0531	amino acid
STho1984_RS21235	COG5510	response to toxic substance
STho1984_RS21265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
STho1984_RS21270	COG1053	succinate dehydrogenase
STho1984_RS21290	COG1511	domain protein
STho1984_RS21290	COG3264	Mechanosensitive ion channel
STho1984_RS21310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STho1984_RS21335	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
STho1984_RS21335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STho1984_RS21340	COG0802	atpase or kinase
STho1984_RS21365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
STho1984_RS21370	COG0330	HflC and HflK could
STho1984_RS21375	COG0330	HflC and HflK could
STho1984_RS21380	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
STho1984_RS21395	COG0557	exoribonuclease II activity
STho1984_RS21405	COG3789	protein conserved in bacteria
STho1984_RS21410	COG1842	Phage shock protein A
STho1984_RS21425	COG3766	membrane
STho1984_RS21430	COG5463	Belongs to the UPF0441 family
STho1984_RS21435	COG0754	glutathionylspermidine amidase activity
STho1984_RS21440	COG1960	acyl-CoA dehydrogenase activity
STho1984_RS21450	COG3650	response to hydrogen peroxide
STho1984_RS21455	COG1073	alpha beta
STho1984_RS21520	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
STho1984_RS21535	COG3061	Opacity-associated protein A
STho1984_RS21540	COG0545	Peptidyl-prolyl cis-trans isomerase
STho1984_RS21545	COG1113	amino acid transport
STho1984_RS21555	COG0697	spore germination
STho1984_RS21560	COG0702	epimerase
STho1984_RS21565	COG1733	regulation of RNA biosynthetic process
STho1984_RS21580	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
STho1984_RS21595	COG1253	flavin adenine dinucleotide binding
STho1984_RS21615	COG2105	PFAM AIG2 family protein
STho1984_RS21620	COG2271	Major facilitator Superfamily
STho1984_RS21625	COG3964	amidohydrolase
STho1984_RS21640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
STho1984_RS21650	COG1737	Transcriptional regulator
STho1984_RS21650	COG0837	glucose binding
STho1984_RS21655	COG2814	Major facilitator Superfamily
STho1984_RS21655	COG0477	Major facilitator Superfamily
STho1984_RS21665	COG2814	Major facilitator Superfamily
STho1984_RS21665	COG0477	Major facilitator Superfamily
STho1984_RS21670	COG3718	enzyme involved in inositol metabolism
STho1984_RS21695	COG5520	Belongs to the glycosyl hydrolase 30 family
STho1984_RS21700	COG1082	Xylose isomerase domain protein TIM barrel
STho1984_RS21710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STho1984_RS21715	COG3962	Belongs to the TPP enzyme family
STho1984_RS21720	COG0673	inositol 2-dehydrogenase activity
STho1984_RS21725	COG2814	Major facilitator Superfamily
STho1984_RS21735	COG1082	Xylose isomerase domain protein TIM barrel
STho1984_RS21745	COG0312	modulator of DNA gyrase
STho1984_RS21780	COG3964	amidohydrolase
STho1984_RS21795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STho1984_RS21795	COG3711	transcriptional antiterminator
STho1984_RS21800	COG3077	Addiction module antitoxin, RelB DinJ family
STho1984_RS21805	COG2026	Addiction module toxin, RelE StbE family
STho1984_RS21825	COG0366	Alpha amylase catalytic
STho1984_RS21830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STho1984_RS21830	COG1263	PTS System
STho1984_RS21865	COG1438	arginine binding
STho1984_RS21870	COG1288	antiporter activity
STho1984_RS21890	COG2731	YhcH YjgK YiaL family protein
STho1984_RS21930	COG2927	DNA polymerase III (CHI subunit)
STho1984_RS21945	COG0795	lipopolysaccharide-transporting ATPase activity
STho1984_RS21950	COG0795	lipopolysaccharide-transporting ATPase activity
STho1984_RS21955	COG1609	Transcriptional regulator
STho1984_RS21960	COG2610	gluconate transmembrane transporter activity
STho1984_RS21965	COG1028	Short-chain dehydrogenase reductase Sdr
STho1984_RS21970	COG1063	alcohol dehydrogenase
STho1984_RS21975	COG3265	gluconokinase activity
STho1984_RS21980	COG1064	alcohol dehydrogenase
STho1984_RS21990	COG0582	viral genome integration into host DNA
STho1984_RS22010	COG4974	Belongs to the 'phage' integrase family
STho1984_RS22100	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
STho1984_RS22125	COG0412	Dienelactone hydrolase
STho1984_RS22130	COG2186	Transcriptional regulator
STho1984_RS22155	COG0583	DNA-binding transcription factor activity
STho1984_RS22160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
STho1984_RS22165	COG0700	Nucleoside recognition
STho1984_RS22170	COG3366	ferrous iron transmembrane transporter activity
STho1984_RS22180	COG0477	Major facilitator Superfamily
STho1984_RS22185	COG2733	membrane
STho1984_RS22195	COG5464	transposase or invertase
STho1984_RS22200	COG1012	belongs to the aldehyde dehydrogenase family
STho1984_RS22215	COG3586	endonuclease activity
STho1984_RS22230	COG0732	type I restriction modification DNA specificity domain
STho1984_RS22250	COG0523	cobalamin synthesis protein
STho1984_RS22255	COG2879	small protein
STho1984_RS22260	COG1966	Carbon starvation protein
STho1984_RS22265	COG0840	transmembrane signaling receptor activity
STho1984_RS22280	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STho1984_RS22285	COG3715	PTS system
STho1984_RS22290	COG3716	PTS system mannose fructose sorbose family IID component
STho1984_RS22295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
STho1984_RS22315	COG1484	DNA-dependent DNA replication
STho1984_RS22330	COG2966	Psort location CytoplasmicMembrane, score
STho1984_RS22335	COG2197	response regulator
STho1984_RS22340	COG2197	response regulator
STho1984_RS22345	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
STho1984_RS22350	COG4114	ferric iron reductase
STho1984_RS22355	COG3706	GGDEF domain
STho1984_RS22385	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
STho1984_RS22395	COG1011	Hydrolase
STho1984_RS22405	COG2823	Periplasmic or secreted lipoprotein
STho1984_RS22415	COG4667	esterase of the alpha-beta hydrolase superfamily
STho1984_RS22420	COG0084	hydrolase, TatD family'
STho1984_RS22425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STho1984_RS22430	COG1328	CTP reductase activity
STho1984_RS22460	COG3188	usher protein
STho1984_RS22465	COG3121	Chaperone
STho1984_RS22470	COG3539	Fimbrial protein
STho1984_RS22485	COG3726	membrane protein affecting hemolysin expression
STho1984_RS22490	COG0560	Phosphoserine phosphatase
STho1984_RS22505	COG0488	(ABC) transporter
STho1984_RS22530	COG3708	Transcriptional regulator
STho1984_RS22530	COG2207	Transcriptional regulator
STho1984_RS22535	COG3045	CreA protein
STho1984_RS22540	COG0745	RESPONSE REGULATOR receiver
STho1984_RS22545	COG2205	protein histidine kinase activity
STho1984_RS22550	COG4452	Inner membrane protein CreD
STho1984_RS22570	COG3121	Chaperone
STho1984_RS22590	COG0745	RESPONSE REGULATOR receiver
STho1984_RS22600	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA