locus-tag class description HF553_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HF553_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HF553_RS00030 ENOG4105CXK mandelate racemase muconate lactonizing HF553_RS00035 ENOG4105DJB Major Facilitator Superfamily HF553_RS00040 ENOG410667J hydrolase HF553_RS00045 ENOG4105EMF GntR family transcriptional regulator HF553_RS00050 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HF553_RS00055 ENOG4108RTU Aldolase HF553_RS00065 ENOG4105DJB Major Facilitator Superfamily HF553_RS00070 ENOG4105BZU Histidine kinase HF553_RS00075 ENOG4108SV3 Tmao reductase system periplasmic protein tort HF553_RS00080 ENOG4106WF9 DNA-binding transcriptional regulator TorR HF553_RS00085 ENOG4105CUW cytochrome C-TYPE protein HF553_RS00090 ENOG4108EM1 reductase HF553_RS00100 ENOG4105CA0 peroxidase HF553_RS00110 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HF553_RS00115 ENOG41060IM Heme exporter protein HF553_RS00120 ENOG4105X3C heme exporter protein HF553_RS00130 ENOG4105DA4 cytochrome c-type biogenesis protein HF553_RS00135 ENOG4107QX9 Thiol disulfide interChange protein HF553_RS00140 ENOG4105KWW Biogenesis protein HF553_RS00145 ENOG4105D99 atp gtp-binding protein HF553_RS00150 ENOG4105R2A (LipO)protein HF553_RS00170 ENOG4105VG5 Membrane HF553_RS00175 ENOG4105JP4 Inner membrane protein yidG HF553_RS00180 ENOG4105J13 transcriptional regulator HF553_RS00195 ENOG4105W8I Transcriptional regulator HF553_RS00205 ENOG4105E5M Multidrug resistance protein D HF553_RS00230 ENOG4105C7K acetolactate synthase HF553_RS00235 ENOG4105M71 acetolactate synthase 1 regulatory subunit HF553_RS00240 ENOG4107FB0 transcriptional regulator DeoR family HF553_RS00250 ENOG4105EDR glucose galactose transporter HF553_RS00260 ENOG4108KX4 response regulator HF553_RS00265 ENOG4105BZU Histidine kinase HF553_RS00270 ENOG4105CXY transporter HF553_RS00275 ENOG4105CXY transporter HF553_RS00280 ENOG4108SAJ Protein of unknown function (DUF1198) HF553_RS00295 ENOG41090UW PTS System HF553_RS00300 ENOG4105DT3 PTS system, galactitol-specific IIc component HF553_RS00310 ENOG4105D2N Aldolase HF553_RS00335 ENOG4105CS2 ec 3.2.1.21 HF553_RS00355 ENOG4105DAS pts system HF553_RS00360 ENOG4105ETZ PTS System HF553_RS00365 ENOG4105F3R pts system mannose fructose sorbose family iid HF553_RS00380 ENOG4105DNE Transposase HF553_RS00385 ENOG4108UZ3 Transporter HF553_RS00395 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HF553_RS00410 ENOG4105CHJ isochorismatase hydrolase HF553_RS00420 ENOG4108TC1 Transcriptional regulator HF553_RS00425 ENOG4105FV3 HF553_RS00435 ENOG4105ISV protein with bipartite regulator domain HF553_RS00455 ENOG4107WZZ SMC domain protein HF553_RS00490 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HF553_RS00500 ENOG4108YGG dna repair protein HF553_RS00505 ENOG4105MFG Antirestriction protein HF553_RS00510 ENOG4106H6R UPF0380 protein HF553_RS00525 ENOG4108PZQ Inner membrane protein YeeR HF553_RS00530 ENOG4105F4K antigen 43 HF553_RS00590 ENOG4105C0D helicase HF553_RS00605 ENOG4107QMH DNA methylase HF553_RS00625 ENOG4105DFP Integrase HF553_RS00635 ENOG4105CT4 transporter HF553_RS00640 ENOG4105CJQ hydrolase, family 31 HF553_RS00645 ENOG4105JV1 AsmA family HF553_RS00650 ENOG4105C2W permease HF553_RS00655 ENOG4105D6U Sodium Glutamate Symporter HF553_RS00660 ENOG4105CB5 ATP-dependent DNA helicase recG HF553_RS00665 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HF553_RS00670 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HF553_RS00690 ENOG4105EN6 Membrane HF553_RS00705 ENOG4105DSJ YicC domain protein HF553_RS00710 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) HF553_RS00730 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HF553_RS00760 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HF553_RS00765 ENOG4105DKP glycosyl transferase, family 9 HF553_RS00770 ENOG4107RJ7 Glycosyl transferase (Group 1 HF553_RS00775 ENOG4107543 (lipo)polysaccharide HF553_RS00780 ENOG4105P7J Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide HF553_RS00785 ENOG4107XU6 Glycosyl transferase (Group 1 HF553_RS00790 ENOG4106AH0 Glycosyl Transferase HF553_RS00795 ENOG4105X1N Glycosyl transferase family 8 HF553_RS00800 ENOG4108PDR lipopolysaccharide core biosynthesis protein HF553_RS00805 ENOG4108QD8 lipopolysaccharide core biosynthesis protein HF553_RS00810 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase HF553_RS00815 ENOG4108FRV O-antigen ligase HF553_RS00820 ENOG4105D16 lipopolysaccharide heptosyltransferase i HF553_RS00825 ENOG4105XA0 heptosyltransferase ii HF553_RS00835 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HF553_RS00845 ENOG4105K64 Glycosyl transferase, family 2 HF553_RS00850 ENOG4105PXI polysaccharide deacetylase HF553_RS00855 ENOG41063SB peptidase HF553_RS00865 ENOG4107YZP Rhodanese domain protein HF553_RS00870 ENOG4105VW4 glutaredoxin 3 HF553_RS00875 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) HF553_RS00880 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase HF553_RS00885 ENOG4105D7W serine acetyltransferase HF553_RS00890 ENOG4105DJB Major Facilitator Superfamily HF553_RS00895 ENOG4105DIA mandelate racemase muconate lactonizing HF553_RS00900 ENOG4105ETE Transcriptional regulator (LacI family HF553_RS00905 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HF553_RS00915 ENOG41073TP transcriptional regulator HF553_RS00920 ENOG4105DAA L-lactate HF553_RS00925 ENOG4105EUR Domain-Containing protein HF553_RS00930 ENOG4108WY4 inner membrane lipoprotein HF553_RS00935 ENOG4108YYI Protein of unknown function (DUF2810) HF553_RS00945 ENOG4105E61 Mannitol repressor protein HF553_RS00950 ENOG4107SQ3 mannitol-1-phosphate 5-dehydrogenase HF553_RS00955 ENOG4105CTS PTS system mannitol-specific HF553_RS00960 ENOG4108U78 Glutathione S-transferase HF553_RS00970 ENOG4105EM7 Selenocysteine-specific translation elongation factor HF553_RS00975 ENOG41066F8 ROK family HF553_RS00980 ENOG4105C26 Dehydrogenase HF553_RS00995 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HF553_RS01000 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HF553_RS01005 ENOG4105H6Q decarboxylase HF553_RS01010 ENOG4105CMG Carbohydrate kinase HF553_RS01015 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HF553_RS01020 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HF553_RS01025 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HF553_RS01030 ENOG4108M5W HF553_RS01035 ENOG4108R66 Conserved Protein HF553_RS01040 ENOG4105DG4 malate L-lactate dehydrogenase HF553_RS01045 ENOG4105J4Q Transcriptional regulator HF553_RS01050 ENOG4108XIB electron transport protein ysaA HF553_RS01055 ENOG4105JKW Valine--pyruvate aminotransferase HF553_RS01060 ENOG4107T9C Alpha amylase catalytic region HF553_RS01065 ENOG4108UR8 BAX protein HF553_RS01070 ENOG4105T16 Transcriptional regulator (AraC family) HF553_RS01075 ENOG4105C93 Xylose Isomerase HF553_RS01080 ENOG4105CMG Carbohydrate kinase HF553_RS01085 ENOG410688U Inner membrane protein yiaB HF553_RS01090 ENOG4105MEV Acyl-transferase HF553_RS01110 ENOG4108RS6 transposase HF553_RS01125 ENOG4105MVF Transcriptional regulator HF553_RS01130 ENOG4106JH6 (LipO)protein HF553_RS01140 ENOG4108ZG0 Ompa motb domain protein HF553_RS01145 ENOG4107QY8 reductase HF553_RS01150 ENOG4105HNP -acetyltransferase HF553_RS01155 ENOG4108R3E Dna-3-methyladenine glycosylase i HF553_RS01160 ENOG4105EAX Putative lipase HF553_RS01165 ENOG4105DIJ Phosphoethanolamine transferase HF553_RS01180 ENOG4108RS6 transposase HF553_RS01190 ENOG4105CQ4 Transcriptional regulator HF553_RS01205 ENOG4105DEF Extracellular solute-binding protein, family 5 HF553_RS01210 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HF553_RS01215 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HF553_RS01220 ENOG4105C3U ABC transporter HF553_RS01225 ENOG4108JQ7 (ABC) transporter HF553_RS01230 ENOG4105C44 Serine transporter HF553_RS01245 ENOG4105D1V cellulose synthase operon protein YhjU HF553_RS01250 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT HF553_RS01260 ENOG410661M cytoplasmic protein HF553_RS01265 ENOG4105UTS cellulose synthase operon protein YhjQ HF553_RS01270 ENOG4107QZ7 Cellulose synthase catalytic subunit HF553_RS01275 ENOG4107EEX Cellulose synthase regulator protein HF553_RS01280 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HF553_RS01285 ENOG4105EJG cellulose synthase HF553_RS01290 ENOG4105BZU Histidine kinase HF553_RS01300 ENOG4105CS0 peptidase HF553_RS01305 ENOG4107SS6 2-dehydro-3-deoxygluconokinase HF553_RS01310 ENOG4105CMB EAL domain-containing protein HF553_RS01315 ENOG41066T0 asmA family HF553_RS01320 ENOG4105CSH Transporter HF553_RS01325 ENOG4107H3J ribonuclease HF553_RS01330 ENOG4105CBN LysR family transcriptional regulator HF553_RS01335 ENOG4106S2D Transcriptional regulator HF553_RS01355 ENOG4105FDP GntR family transcriptional regulator HF553_RS01360 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine HF553_RS01365 ENOG4108KPW sugar kinase HF553_RS01370 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HF553_RS01380 ENOG4105DC8 reductase HF553_RS01385 ENOG4105D6S protein involved in catabolism of external DNA HF553_RS01390 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HF553_RS01395 ENOG4105DGW oligopeptidase A HF553_RS01405 ENOG4105DUX Transporter HF553_RS01410 ENOG4108M6U Universal stress protein A HF553_RS01420 ENOG4105CJ3 phosphate transporter HF553_RS01425 ENOG4105CBX hi0933 family HF553_RS01430 ENOG4105D0S secretion protein (HlyD HF553_RS01435 ENOG4105CJ1 ABC, transporter HF553_RS01440 ENOG4105CMI transporter HF553_RS01450 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HF553_RS01455 ENOG4105DSF transport protein HF553_RS01465 ENOG4108W1V Lipoprotein HF553_RS01470 ENOG4105EX9 Membrane HF553_RS01480 ENOG4105C8Q Methyl-accepting chemotaxis HF553_RS01490 ENOG4107FS9 Membrane HF553_RS01500 ENOG4105MG3 Membrane HF553_RS01505 ENOG4106H78 methyltransferase HF553_RS01510 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HF553_RS01515 ENOG4105CAK Cell division ATP-binding protein ftsE HF553_RS01520 ENOG4105CRP Part of the ABC transporter FtsEX involved in HF553_RS01530 ENOG4105CP9 extracellular ligand-binding receptor HF553_RS01540 ENOG4105U59 -acetyltransferase HF553_RS01545 ENOG4105CP9 extracellular ligand-binding receptor HF553_RS01550 ENOG4105C32 Amino acid ABC transporter (Permease) HF553_RS01555 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HF553_RS01560 ENOG4105C0Z ABC transporter HF553_RS01565 ENOG4108IV0 ABC, transporter HF553_RS01575 ENOG4105BZ7 extracellular solute-binding protein family 1 HF553_RS01590 ENOG4108IJ9 (ABC) transporter HF553_RS01595 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HF553_RS01600 ENOG4105WC8 Conserved Protein HF553_RS01605 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HF553_RS01610 ENOG41080QX K07048 phosphotriesterase-related protein HF553_RS01625 ENOG4108RVA ribokinase HF553_RS01630 ENOG4105WCN acetyltransferase HF553_RS01635 ENOG4105D9R oxidoreductase HF553_RS01640 ENOG4105C2I pirin domain protein HF553_RS01645 ENOG4105DIQ Transcriptional regulator HF553_RS01650 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HF553_RS01655 ENOG4105C6Z Gluconate HF553_RS01665 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HF553_RS01670 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) HF553_RS01690 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HF553_RS01695 ENOG4107HP6 Transcriptional regulator HF553_RS01700 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HF553_RS01705 ENOG4105C01 Dihydroxy-acid dehydratase HF553_RS01715 ENOG4105DCT glycerol dehydrogenase HF553_RS01730 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HF553_RS01745 ENOG4105E98 transcriptional regulator DeoR family HF553_RS01755 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HF553_RS01760 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HF553_RS01765 ENOG4105C6Z Gluconate HF553_RS01775 ENOG4105MJ2 Competence protein HF553_RS01785 ENOG4105DNE Transposase HF553_RS01800 ENOG4105XFK Ferrous iron transport protein A HF553_RS01805 ENOG4105BZM domain protein HF553_RS01810 ENOG4108RRZ Transcription elongation factor GreB HF553_RS01820 ENOG4105E0F Histidine kinase HF553_RS01830 ENOG4108MAJ Membrane HF553_RS01840 ENOG4105VEJ Heat shock protein HF553_RS01845 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HF553_RS01855 ENOG4107RK2 ADP-ribose diphosphatase NudE HF553_RS01860 ENOG4108JQC penicillin-binding protein 1A HF553_RS01865 ENOG4108U1Q Pilus assembly protein HF553_RS01870 ENOG41065NF Fimbrial assembly family protein HF553_RS01875 ENOG4105XPX DNA utilization protein HofO HF553_RS01880 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HF553_RS01885 ENOG4105E4G Type IV pilus HF553_RS01900 ENOG4105EGB membrane protein DamX HF553_RS01905 ENOG4105DFE Dna adenine methylase HF553_RS01910 ENOG4105DJV ribulose-phosphate 3-epimerase HF553_RS01920 ENOG4105C31 Tryptophanyl-tRNA synthetase HF553_RS01925 ENOG4105VYH HF553_RS01930 ENOG4107EF2 surface-exposed virulence protein HF553_RS01935 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) HF553_RS01940 ENOG4107V9H nitrite transporter HF553_RS01945 ENOG4105WZK nitrite reductase NADPH small subunit HF553_RS01950 ENOG4107QZF nitrite reductase NADPH large subunit HF553_RS01960 ENOG4106DTQ Protein TsgA homolog HF553_RS01965 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HF553_RS01970 ENOG4106195 uncharacterized protein yhfG HF553_RS01975 ENOG4105MZU cell filamentation protein HF553_RS01980 ENOG4105DDQ anthranilate synthase HF553_RS01985 ENOG4105C8Y Acetylornithine aminotransferase HF553_RS01990 ENOG410613R integral membrane protein, YccS YhfK family HF553_RS01995 ENOG4107RYR Transcriptional regulator, Crp Fnr family HF553_RS02000 ENOG4108UKZ OsmC family HF553_RS02005 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HF553_RS02015 ENOG4105DNZ Alpha Beta Hydrolase HF553_RS02020 ENOG4105N0V mono-oxygenase ydhR HF553_RS02025 ENOG4108K70 Transcriptional regulator HF553_RS02030 ENOG4105C5H ABC transporter HF553_RS02045 ENOG4105VKU nucleicacid-binding protein HF553_RS02050 ENOG4108YZY peptidylprolyl cis-trans isomerase HF553_RS02055 ENOG4105VRX Protein slyX homolog HF553_RS02060 ENOG4108V1T peptidylprolyl cis-trans isomerase HF553_RS02065 ENOG4105WWK YheO domain protein HF553_RS02090 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) HF553_RS02100 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) HF553_RS02105 ENOG4105W53 bacterioferritin-associated ferredoxin HF553_RS02110 ENOG4108UQY Iron-storage protein HF553_RS02115 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) HF553_RS02145 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) HF553_RS02165 ENOG41083MP 50s ribosomal protein l29 HF553_RS02170 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal HF553_RS02180 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) HF553_RS02205 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) HF553_RS02215 ENOG4105VPB 50S ribosomal protein L30 HF553_RS02225 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HF553_RS02230 ENOG41067V7 50S ribosomal protein L36 HF553_RS02245 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) HF553_RS02260 ENOG4105VTS DnaJ-like, subfamily C HF553_RS02265 ENOG4105W1Y Transcriptional regulator HF553_RS02270 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HF553_RS02275 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) HF553_RS02280 ENOG4105C1A potassium transporter peripheral membrane HF553_RS02300 ENOG4105C79 DNA protecting protein DprA HF553_RS02310 ENOG4108WI1 Dna topoisomerase HF553_RS02325 ENOG4105SG3 Protein of unknown function (DUF1488) HF553_RS02330 ENOG4108Z0R Transferase HF553_RS02370 ENOG4105XCM membrane LIPOPROTEIN HF553_RS02375 ENOG4105BZS acriflavin resistance protein HF553_RS02380 ENOG4105C1P efflux transporter, rnd family, mfp subunit HF553_RS02385 ENOG4108XG4 DNA-binding transcriptional regulator HF553_RS02390 ENOG4105BZU Histidine kinase HF553_RS02395 ENOG41061ME transport protein HF553_RS02400 ENOG4105CEC DNA methylase N-4 N-6 HF553_RS02410 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HF553_RS02425 ENOG4108IA2 Sodium pantothenate symporter HF553_RS02430 ENOG4105RG0 Membrane HF553_RS02435 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HF553_RS02440 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HF553_RS02455 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HF553_RS02460 ENOG41062P1 Diguanylate cyclase phosphodiesterase HF553_RS02470 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HF553_RS02475 ENOG4105VQ7 Rod shape-determining protein MreD HF553_RS02485 ENOG4105C03 ribonuclease HF553_RS02490 ENOG4105QD6 exported protein HF553_RS02495 ENOG4105D1U peptidase U62 modulator of DNA gyrase HF553_RS02500 ENOG4105CR8 Transcriptional regulator HF553_RS02505 ENOG4105ZQC membrane protein AaeX HF553_RS02520 ENOG4108RS6 transposase HF553_RS02525 ENOG4105UNR (Barnase) inhibitor HF553_RS02530 ENOG4105RID UPF0379 protein yhcN HF553_RS02535 ENOG4105RID UPF0379 protein yhcN HF553_RS02560 ENOG4105C8P )-transporter HF553_RS02565 ENOG4106DSS Tartrate dehydratase subunit alpha HF553_RS02570 ENOG4107GFK fumarate HF553_RS02580 ENOG4107QSA Oxaloacetate decarboxylase HF553_RS02585 ENOG4105D9Q decarboxylase (Beta subunit) HF553_RS02600 ENOG4105C0H protease HF553_RS02605 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HF553_RS02610 ENOG4105D6Z AFG1 family ATPase HF553_RS02630 ENOG4107MKT Stringent starvation protein a HF553_RS02635 ENOG4105KB2 stringent starvation protein b HF553_RS02665 ENOG4108R66 Conserved Protein HF553_RS02670 ENOG4105DZC cytosine deaminase HF553_RS02675 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HF553_RS02680 ENOG4105DFS Conserved Protein HF553_RS02685 ENOG4105BZ8 glutamate synthase HF553_RS02690 ENOG4105CBC glutamate synthase HF553_RS02695 ENOG4105N5T Radical SAM Protein HF553_RS02700 ENOG4105BZU Histidine kinase HF553_RS02705 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HF553_RS02715 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HF553_RS02720 ENOG41080Z8 PHOSPHOCARRIER protein HF553_RS02730 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HF553_RS02735 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HF553_RS02740 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HF553_RS02745 ENOG4108IUZ ABC transporter HF553_RS02750 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HF553_RS02755 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HF553_RS02760 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase HF553_RS02765 ENOG4105C2X Arabinose 5-phosphate isomerase HF553_RS02770 ENOG4105FEU K -dependent Na -Ca exchanger HF553_RS02775 ENOG4105DHJ ABC, transporter HF553_RS02780 ENOG4105CY3 ABC transporter, permease HF553_RS02785 ENOG4107PE3 Mammalian cell entry related domain protein HF553_RS02790 ENOG4105E3I toluene tolerance HF553_RS02795 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HF553_RS02800 ENOG4105VFK BolA family HF553_RS02810 ENOG4105HVQ Regulatory factor of maltose metabolism HF553_RS02815 ENOG4105EAH synthase HF553_RS02825 ENOG4105K46 50S ribosomal protein l27 HF553_RS02830 ENOG4105QYV Membrane HF553_RS02840 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HF553_RS02845 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HF553_RS02850 ENOG4105HBR Rna-binding protein HF553_RS02860 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HF553_RS02865 ENOG4105EEI dihydropteroate synthase HF553_RS02875 ENOG4105NTZ Preprotein translocase subunit SecG HF553_RS02900 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) HF553_RS02905 ENOG4105CHV Transcription elongation factor NusA HF553_RS02945 ENOG4105C1J atp-dependent rna helicase HF553_RS02950 ENOG4105CIC tryptophan-specific transport protein HF553_RS02960 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HF553_RS02965 ENOG4105DEN Luciferase family HF553_RS02985 ENOG4108YYD acetyltransferase HF553_RS03000 ENOG4107R7Y intracellular protease Pfpi family HF553_RS03005 ENOG4105K4T epimerase HF553_RS03010 ENOG4105W4M Transport-associated protein HF553_RS03025 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) HF553_RS03030 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HF553_RS03040 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HF553_RS03045 ENOG4105DT3 PTS system, galactitol-specific IIc component HF553_RS03050 ENOG41090UW PTS System HF553_RS03055 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HF553_RS03070 ENOG4105CTX dehydratase HF553_RS03080 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HF553_RS03085 ENOG4105BZW Glycerate kinase HF553_RS03095 ENOG410811B TRANSCRIPTIONal HF553_RS03100 ENOG4105C7B Threonine dehydratase HF553_RS03110 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HF553_RS03115 ENOG4105C6N Formate acetyltransferase HF553_RS03120 ENOG4105EJQ L-serine dehydratase HF553_RS03125 ENOG4105C44 Serine transporter HF553_RS03135 ENOG4106D80 Uncharacterized protein YhaL HF553_RS03140 ENOG4108CNN domain protein HF553_RS03145 ENOG4105CWB LysR family transcriptional Regulator HF553_RS03150 ENOG4105KAF membrAne HF553_RS03155 ENOG4105CHF Glutathione S-transferase HF553_RS03160 ENOG4108VBZ doxx family HF553_RS03165 ENOG4105YJD HF553_RS03170 ENOG41090KG Inner membrane protein YqjE HF553_RS03175 ENOG4105NE1 Conserved Protein HF553_RS03180 ENOG4105WAY exported protein HF553_RS03190 ENOG4106W5V Membrane HF553_RS03200 ENOG4105DU1 integral membrane protein, terc HF553_RS03205 ENOG4105EE0 oxidoreductase HF553_RS03210 ENOG4108UB4 uncharacterized protein ygjQ HF553_RS03215 ENOG4108VKG metal-dependent hydrolase HF553_RS03225 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HF553_RS03235 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HF553_RS03245 ENOG4105C8Q Methyl-accepting chemotaxis HF553_RS03250 ENOG4105NTW Transcriptional regulator HF553_RS03255 ENOG4105Q26 Siderophore-interacting protein HF553_RS03260 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HF553_RS03275 ENOG4105MEH HF553_RS03305 ENOG4108IRC dna polymerase iii HF553_RS03315 ENOG4105DFE Dna adenine methylase HF553_RS03320 ENOG4105VZ1 Replication Protein HF553_RS03335 ENOG4105ED4 portal protein HF553_RS03430 ENOG4108X9F tail fiber protein HF553_RS03485 ENOG410693A DNA-binding protein HF553_RS03490 ENOG4105JXR Protein of unknown function (DUF3296) HF553_RS03530 ENOG4105C5Y PTS System HF553_RS03545 ENOG4105D7K pfkb domain protein HF553_RS03565 ENOG4105EKQ RNA-directed DNA polymerase HF553_RS03575 ENOG4105ECI YeeC-like protein HF553_RS03580 ENOG4105F6A helicase HF553_RS03585 ENOG4105D85 methylase HF553_RS03615 ENOG4105F4K antigen 43 HF553_RS03625 ENOG4106H6R UPF0380 protein HF553_RS03630 ENOG4105MFG Antirestriction protein HF553_RS03635 ENOG4108YGG dna repair protein HF553_RS03650 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HF553_RS03675 ENOG4108KU3 Integrase HF553_RS03710 ENOG4105KSC Transcriptional regulator, TraR DksA family HF553_RS03715 ENOG4105DFE Dna adenine methylase HF553_RS03745 ENOG4105ED4 portal protein HF553_RS03830 ENOG4108X9F tail fiber protein HF553_RS03875 ENOG4105ZTC transcriptional activator, Ogr delta HF553_RS03890 ENOG4108VCA G U mismatch-specific DNA glycosylase HF553_RS03895 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HF553_RS03900 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HF553_RS03930 ENOG4107ZVW dihydroneopterin aldolase HF553_RS03945 ENOG4106MWK domain protein HF553_RS03950 ENOG4105I7R Adenylate cyclase HF553_RS03970 ENOG4107S78 Band 7 protein HF553_RS03975 ENOG4105PV3 Inner membrane protein yqiJ HF553_RS03985 ENOG4105W0Z cytoplasmic protein HF553_RS03995 ENOG4108PSN Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity) HF553_RS04005 ENOG4108MR7 Arylsulfotransferase HF553_RS04015 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HF553_RS04020 ENOG4106032 Glutathionylspermidine synthase HF553_RS04025 ENOG4105F1G UPF0441 protein HF553_RS04035 ENOG41087AY ADP-Ribose pyrophosphatase HF553_RS04040 ENOG4108SX3 cytoplasmic protein HF553_RS04045 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HF553_RS04050 ENOG4105IPS esterase HF553_RS04055 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HF553_RS04060 ENOG4105VRH Antibiotic biosynthesis monooxygenase HF553_RS04065 ENOG4105NF4 modulator of drug activity HF553_RS04070 ENOG4105DHQ Histidine kinase HF553_RS04075 ENOG4105XJC Two component transcriptional regulator (Winged helix family HF553_RS04080 ENOG4105H4F exported protein HF553_RS04085 ENOG4105F4I Transcriptional regulator HF553_RS04090 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HF553_RS04095 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HF553_RS04100 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HF553_RS04125 ENOG4105CCT upf0313 protein HF553_RS04135 ENOG4107QPK )-transporter HF553_RS04140 ENOG4105CV8 reductase HF553_RS04145 ENOG4108I6A alcohol dehydrogenase HF553_RS04150 ENOG4105CF7 AraC family transcriptional regulator HF553_RS04155 ENOG4108K81 inner membrane protein YghB HF553_RS04160 ENOG4105C28 cystathionine HF553_RS04165 ENOG4105CWK Biopolymer transport protein, ExbB HF553_RS04170 ENOG4108ZZF transport protein (ExbD) HF553_RS04175 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HF553_RS04200 ENOG4105C8Q Methyl-accepting chemotaxis HF553_RS04205 ENOG410900S Protein of unknown function (DUF2623) HF553_RS04210 ENOG4105E3S small subunit HF553_RS04215 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HF553_RS04220 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HF553_RS04225 ENOG4105DPX Hydrogenase, large subunit HF553_RS04230 ENOG4108USZ hydrogenase HF553_RS04235 ENOG4108WGS hydrogenase 2-specific chaperone HF553_RS04240 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HF553_RS04245 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HF553_RS04250 ENOG4105S10 periplasmic binding protein HF553_RS04255 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein HF553_RS04260 ENOG4105CYM Glutathione S-transferase HF553_RS04265 ENOG4106032 Glutathionylspermidine synthase HF553_RS04280 ENOG4105DEI Mannitol dehydrogenase HF553_RS04290 ENOG4105DPW Major facilitator superfamily MFS_1 HF553_RS04315 ENOG4105C26 Dehydrogenase HF553_RS04320 ENOG4105CJP fad dependent oxidoreductase HF553_RS04330 ENOG4105CUB amino acid HF553_RS04340 ENOG4108UAJ Transcriptional regulator HF553_RS04345 ENOG4105E3J oxidoreductase HF553_RS04350 ENOG41066GK UPF0379 protein ykgI HF553_RS04370 ENOG4105X54 addiction module antidote protein HF553_RS04415 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HF553_RS04425 ENOG4108YGG dna repair protein HF553_RS04430 ENOG4106549 Antirestriction protein HF553_RS04435 ENOG4106H6R UPF0380 protein HF553_RS04450 ENOG4105TS0 gtp-binding protein HF553_RS04540 ENOG4108R0M Aminoglycoside HF553_RS04605 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein HF553_RS04640 ENOG4107SCJ type I restriction enzyme EcoKI subunit R HF553_RS04655 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) HF553_RS04670 ENOG4105T40 surface antigen msp4 family protein HF553_RS04700 ENOG4105DIJ Phosphoethanolamine transferase HF553_RS04745 ENOG4105DFP Integrase HF553_RS04755 ENOG4108UQV Membrane HF553_RS04760 ENOG4105CXN decarboxylase HF553_RS04765 ENOG4105EAA nucleoside HF553_RS04775 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) HF553_RS04780 ENOG4105CEN a g-specific adenine glycosylase HF553_RS04790 ENOG41090ED Protein with unknown function (DUF469) HF553_RS04795 ENOG4105K33 Periplasmic Protein HF553_RS04800 ENOG4105HDK L-asparaginase HF553_RS04805 ENOG4106MH3 alpha helix chain HF553_RS04810 ENOG4105CSA Coproporphyrinogen iii oxidase HF553_RS04815 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HF553_RS04825 ENOG4108VIA integral membrane protein HF553_RS04830 ENOG4105DFA alanine racemase domain protein HF553_RS04835 ENOG4105CZX twitching motility protein HF553_RS04855 ENOG4105D7Z glutathione synthase HF553_RS04860 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HF553_RS04865 ENOG4105RWS endonuclease I HF553_RS04875 ENOG4107QNK )-transporter HF553_RS04900 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HF553_RS04910 ENOG4108K0D peptidase, M48 HF553_RS04915 ENOG4105CV1 Transketolase (EC 2.2.1.1) HF553_RS04920 ENOG4108JJB ABC transporter HF553_RS04925 ENOG4108JJB ABC transporter HF553_RS04950 ENOG4105BZA Phosphoglycerate kinase HF553_RS04955 ENOG4105D2N Aldolase HF553_RS04960 ENOG4105D64 Mechanosensitive ion channel HF553_RS04970 ENOG4105MPN Membrane HF553_RS04990 ENOG4108JQ1 Dehydrogenase HF553_RS04995 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HF553_RS05015 ENOG4107RAQ aminopeptidase HF553_RS05020 ENOG4105D0A hydroxylase HF553_RS05025 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HF553_RS05050 ENOG4105CS2 ec 3.2.1.21 HF553_RS05060 ENOG4108UT2 hemolysin iii HF553_RS05080 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HF553_RS05085 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HF553_RS05090 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HF553_RS05095 ENOG4105T95 Thiol disulfide interChange protein HF553_RS05100 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HF553_RS05120 ENOG4108K5P (LipO)protein HF553_RS05140 ENOG4105VGJ Virulence-associated protein HF553_RS05145 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A HF553_RS05150 ENOG4108T1M outer membrane protein x HF553_RS05170 ENOG4106P2F Pfam:Pili_assembly_C HF553_RS05200 ENOG4108MHD transport protein HF553_RS05210 ENOG4105C5Q Transcriptional regulator HF553_RS05215 ENOG4105CHU acetyl-coa acetyltransferase HF553_RS05225 ENOG4105CHR reductase HF553_RS05230 ENOG4107QNK )-transporter HF553_RS05240 ENOG4105RQF LysR family Transcriptional regulator HF553_RS05250 ENOG4105DDV Transcriptional regulator (LacI family HF553_RS05270 ENOG4105CPC Aldo Keto reductase HF553_RS05275 ENOG4105SUV lipoprotein YgdR HF553_RS05280 ENOG4105EE5 Membrane protein terC HF553_RS05295 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HF553_RS05310 ENOG4105IPU prepilin peptidase dependent protein A HF553_RS05315 ENOG4105JCS prepilin peptidase dependent protein HF553_RS05320 ENOG4105SEN Protein of unknown function (DUF2509) HF553_RS05325 ENOG4105RVB Prepilin peptidase dependent protein c HF553_RS05330 ENOG4105DSY exodeoxyribonuclease V, gamma HF553_RS05335 ENOG4107QXK peptidase HF553_RS05340 ENOG4107QKA exodeoxyribonuclease V beta HF553_RS05345 ENOG4107QYX exodeoxyribonuclease v alpha HF553_RS05350 ENOG4108EKC n-acetylglutamate synthase HF553_RS05355 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HF553_RS05370 ENOG4105CA3 membrane-bound lytic murein transglycosylase HF553_RS05375 ENOG4105CUZ uba thif-type nad fad binding protein HF553_RS05380 ENOG4105FR1 rard protein HF553_RS05385 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HF553_RS05390 ENOG4105C9B Cysteine desulfurase HF553_RS05395 ENOG4105M5B (LipO)protein HF553_RS05400 ENOG4105ETT transcriptional Regulator, LysR family HF553_RS05405 ENOG4105M08 Membrane HF553_RS05415 ENOG4107EDW L-fucose operon activator HF553_RS05425 ENOG4105CMG Carbohydrate kinase HF553_RS05435 ENOG4105EDR glucose galactose transporter HF553_RS05440 ENOG4107W7X Aldolase HF553_RS05445 ENOG4105C0A alcohol dehydrogenase HF553_RS05455 ENOG4105EJQ L-serine dehydratase HF553_RS05460 ENOG4105C44 Serine transporter HF553_RS05465 ENOG4105EWT decarboxylase family HF553_RS05485 ENOG4105DR9 pseudouridine synthase HF553_RS05490 ENOG4105QDK Flavodoxin HF553_RS05500 ENOG4105DJB Major Facilitator Superfamily HF553_RS05505 ENOG4105EQX glucarate dehydratase HF553_RS05510 ENOG4105EQX glucarate dehydratase HF553_RS05515 ENOG4105BZW Glycerate kinase HF553_RS05520 ENOG4105BZU Histidine kinase HF553_RS05525 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) HF553_RS05530 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HF553_RS05535 ENOG4105X54 addiction module antidote protein HF553_RS05565 ENOG4105NEV Fimbrial HF553_RS05570 ENOG4108FZ9 Chaperone HF553_RS05575 ENOG4106PG1 outer membrane usher protein HF553_RS05585 ENOG4105DXN mazG family HF553_RS05595 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) HF553_RS05600 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HF553_RS05605 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) HF553_RS05610 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HF553_RS05625 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) HF553_RS05635 ENOG4105DTT CRISPR-associated helicase, cas3 HF553_RS05650 ENOG41060M0 Crispr-associated protein, cse4 family HF553_RS05655 ENOG4108VWQ crispr-associated protein HF553_RS05665 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) HF553_RS05670 ENOG4105PWE CRISPR-associated protein cas2 HF553_RS05675 ENOG4108MXK alkaline phosphatase isozyme conversion HF553_RS05695 ENOG4105N0Z inner membrane protein ygbE HF553_RS05730 ENOG4108K5P (LipO)protein HF553_RS05740 ENOG4105KZM cytoplasmic protein HF553_RS05745 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HF553_RS05750 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HF553_RS05760 ENOG4105MVE transcriptional regulator HF553_RS05770 ENOG4105G63 Type III effector Hrp-dependent HF553_RS05780 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HF553_RS05785 ENOG4105EXW epimerase dehydratase HF553_RS05790 ENOG4105C6Z Gluconate HF553_RS05795 ENOG4105JQN Transcriptional regulator HF553_RS05800 ENOG4105C0R drug resistance transporter emrb qaca subfamily HF553_RS05835 ENOG4105MEW serine threonine protein phosphatase HF553_RS05880 ENOG41090HZ type iii secretion HF553_RS05890 ENOG4108N8R Invasion protein HF553_RS05895 ENOG4108HR8 type iii secretion HF553_RS05900 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone HF553_RS05905 ENOG4108JIR Flagellum-specific ATP synthase HF553_RS05910 ENOG41077MC Secretory protein (Associated with virulence) HF553_RS05915 ENOG41078G4 surface presentation of HF553_RS05920 ENOG4105T85 surface presentation of antigens protein HF553_RS05925 ENOG41075IY surface presentation of antigens protein SpaP HF553_RS05930 ENOG4105U07 type iii secretion HF553_RS05935 ENOG4108TN6 type iii secretion HF553_RS05940 ENOG4108M6W surface presentation of antigens protein SpaS HF553_RS05950 ENOG4106H1J Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE HF553_RS05960 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC HF553_RS05965 ENOG4105MH6 Actin-binding protein that interferes with host cell actin cytoskeleton. It stimulates actin polymerization and counteracts F-actin destabilizing proteins. Potentiates SipC activity HF553_RS05970 ENOG41079WB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HF553_RS05985 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear HF553_RS05995 ENOG4108YAB Invasion protein HF553_RS06005 ENOG4108RC9 Type III secretion system protein HF553_RS06010 ENOG4105Y7Q type iii secretion HF553_RS06015 ENOG4106BTR HF553_RS06020 ENOG4108RBT type iii secretion HF553_RS06050 ENOG4105CC5 ABC transporter HF553_RS06055 ENOG4105CC5 ABC transporter HF553_RS06060 ENOG4105DIK (ABC) transporter HF553_RS06070 ENOG4105VXR cytoplasmic protein HF553_RS06080 ENOG4105C45 hydrogenase expression formation protein (HypE) HF553_RS06085 ENOG4105CQS hydrogenase expression formation protein HypD HF553_RS06090 ENOG41083WG hydrogenase assembly chaperone HF553_RS06095 ENOG4107RSS Hydrogenase accessory protein HypB HF553_RS06100 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HF553_RS06105 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HF553_RS06110 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HF553_RS06115 ENOG4107R30 NADH dehydrogenase HF553_RS06120 ENOG4107TDF Formate hydrogenlyase subunit 4 HF553_RS06125 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HF553_RS06130 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HF553_RS06135 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HF553_RS06140 ENOG4105I6X formate hydrogenlyase maturation HF553_RS06145 ENOG4108MG9 hydrogenase 3 maturation protease HF553_RS06155 ENOG4108RC0 Electron transport protein HF553_RS06160 ENOG4105C8H hydrogenase maturation protein Hypf HF553_RS06180 ENOG4105C2X Arabinose 5-phosphate isomerase HF553_RS06185 ENOG410804X Transcriptional regulator HF553_RS06190 ENOG4105J92 DNA-binding transcriptional activator GutM HF553_RS06195 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HF553_RS06200 ENOG4105VI0 Pts system, glucitol sorbitol-specific HF553_RS06205 ENOG4105DZY Pts system, glucitol sorbitol-specific HF553_RS06210 ENOG410787A Pts system, glucitol sorbitol-specific HF553_RS06215 ENOG4105CVE Lytic murein transglycosylase HF553_RS06220 ENOG4107TH8 cina domain protein HF553_RS06235 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) HF553_RS06240 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HF553_RS06270 ENOG4107VXZ Hydrolase HF553_RS06275 ENOG4105W39 Membrane HF553_RS06295 ENOG4105C0R drug resistance transporter emrb qaca subfamily HF553_RS06300 ENOG4105CW7 secretion protein, HlyD family HF553_RS06305 ENOG4105NTK Transcriptional repressor Mpra HF553_RS06315 ENOG4105GIJ Glycine betaine HF553_RS06320 ENOG4108HQS Glycine betaine HF553_RS06325 ENOG4108IJ7 Glycine betaine HF553_RS06330 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HF553_RS06335 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HF553_RS06345 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HF553_RS06350 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HF553_RS06360 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HF553_RS06365 ENOG4108WMJ Protein of unknown function (DUF2002) HF553_RS06370 ENOG4108RNS Exports L-alanine (By similarity) HF553_RS06375 ENOG4108X73 DNA- binding protein HF553_RS06385 ENOG4108V62 Rhodanese domain protein HF553_RS06390 ENOG41080HT Transcriptional regulator, arsr family HF553_RS06395 ENOG4105VPI YqaE family transport protein HF553_RS06400 ENOG4109066 lysm domain bon superfamily protein HF553_RS06405 ENOG4108PVQ transcriptional regulator HF553_RS06410 ENOG4105C85 amino acid HF553_RS06415 ENOG4108JPW Aminotransferase HF553_RS06420 ENOG4105C26 Dehydrogenase HF553_RS06425 ENOG4105D5U fad dependent oxidoreductase HF553_RS06455 ENOG4105DHQ Histidine kinase HF553_RS06470 ENOG4108MJ5 VirK protein HF553_RS06485 ENOG4107RNH Outer membrane receptor FepA HF553_RS06490 ENOG4105NIV Esterase HF553_RS06510 ENOG4108C33 Resolvase HF553_RS06515 ENOG4105I03 Flagellin HF553_RS06555 ENOG4105DFP Integrase HF553_RS06590 ENOG4108Z1B Cyclase dehydrase HF553_RS06600 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HF553_RS06605 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HF553_RS06625 ENOG4108JU6 CBS domain protein HF553_RS06630 ENOG4106KVJ cytochrome C assembly protein HF553_RS06635 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HF553_RS06655 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) HF553_RS06660 ENOG4108KHX Diguanylate cyclase HF553_RS06665 ENOG4108WS1 HF553_RS06670 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HF553_RS06675 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HF553_RS06685 ENOG4105CQC Prephenate dehydratase HF553_RS06695 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HF553_RS06735 ENOG4105ED4 portal protein HF553_RS06825 ENOG4108X9F tail fiber protein HF553_RS06855 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HF553_RS06860 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HF553_RS06865 ENOG4105C34 Pseudouridine synthase HF553_RS06870 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HF553_RS06875 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HF553_RS06905 ENOG4105CSH Transporter HF553_RS06910 ENOG4105T42 (LipO)protein HF553_RS06915 ENOG4105JIM Phosphatidylserine synthase HF553_RS06920 ENOG4105CD5 CoA-binding domain protein HF553_RS06925 ENOG4106IUH DTW domain containing protein HF553_RS06930 ENOG4105K63 Thioredoxin HF553_RS06935 ENOG4105EIB trna rrna methyltransferase HF553_RS06945 ENOG4108VKA Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity) HF553_RS06955 ENOG41090KR LysR family transcriptional Regulator HF553_RS06960 ENOG4105C1J atp-dependent rna helicase HF553_RS06970 ENOG4108IYU L-aspartate oxidase HF553_RS06995 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HF553_RS07005 ENOG4105C3F Signal peptidase i HF553_RS07035 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HF553_RS07040 ENOG4105DND Transcriptional regulator HF553_RS07050 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HF553_RS07055 ENOG4106G6Q Transcriptional regulator HF553_RS07070 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HF553_RS07075 ENOG4108Z6B deaminase HF553_RS07080 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) HF553_RS07090 ENOG4108ETH Formylglycinamide ribotide synthetase HF553_RS07095 ENOG4107WP9 Histidine kinase HF553_RS07100 ENOG4108SKK alpha helix protein HF553_RS07105 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HF553_RS07115 ENOG4105DUX Transporter HF553_RS07120 ENOG4105CXN decarboxylase HF553_RS07125 ENOG4105D5Q Arginine ornithine antiporter HF553_RS07130 ENOG4108M3R transcriptional activator CadC HF553_RS07140 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HF553_RS07150 ENOG4105D8G Major Facilitator superfamily HF553_RS07155 ENOG4108MN2 Stationary phase inducible protein CsiE HF553_RS07165 ENOG4105D7X high-affinity nickel-transporter HF553_RS07170 ENOG410810Y Sulfite reductase HF553_RS07175 ENOG4107SHJ sulfite reductase subunit b HF553_RS07185 ENOG4107XM9 (LipO)protein HF553_RS07190 ENOG4105ECY inositol monophosphatase HF553_RS07195 ENOG4105CVS RNA methyltransferase TrmH family, group 1 HF553_RS07210 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HF553_RS07215 ENOG4108Z4V iron-sulfur cluster assembly HF553_RS07230 ENOG4108ZIT Ferredoxin, 2FE-2S HF553_RS07235 ENOG4105WVQ Fe-S assembly protein IscX HF553_RS07245 ENOG4105YYA enhanced serine sensitivity protein SseB HF553_RS07255 ENOG4105KHC sulfurtransferase HF553_RS07260 ENOG4105DN3 alpha-2-macroglobulin domain protein HF553_RS07265 ENOG4108JQB penicillin-binding protein 1C HF553_RS07270 ENOG4107QY8 reductase HF553_RS07275 ENOG4105QAX Iron-sulfur HF553_RS07315 ENOG4105N21 Membrane HF553_RS07320 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HF553_RS07330 ENOG4105VPD cellular component movement HF553_RS07370 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HF553_RS07390 ENOG41066DY Membrane HF553_RS07395 ENOG4108ZMA Outer membrane lipoprotein HF553_RS07400 ENOG41062G3 Protein of unknown function (DUF2633) HF553_RS07410 ENOG4105BZU Histidine kinase HF553_RS07415 ENOG4105C9X ppx gppa phosphatase HF553_RS07420 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HF553_RS07425 ENOG4108V3E phosphoribosylglycinamide formyltransferase HF553_RS07435 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) HF553_RS07440 ENOG4105C2W permease HF553_RS07450 ENOG4105K89 arsenate reductase HF553_RS07455 ENOG4105ERG peptidase m48, ste24p HF553_RS07460 ENOG4105C02 permease HF553_RS07465 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HF553_RS07470 ENOG4107QQ0 gntp family HF553_RS07475 ENOG4105BZW Glycerate kinase HF553_RS07480 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HF553_RS07485 ENOG4105RH4 Glycine cleavage system transcriptional repressor HF553_RS07490 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HF553_RS07495 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HF553_RS07505 ENOG4105CGZ zinc metallopeptidase HF553_RS07510 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) HF553_RS07520 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) HF553_RS07525 ENOG4105KUZ arsenate reductase HF553_RS07535 ENOG4105BZS acriflavin resistance protein HF553_RS07540 ENOG4105BZU Histidine kinase HF553_RS07545 ENOG4105BZ8 glutamate synthase HF553_RS07555 ENOG4107VIJ nudix hydrolase HF553_RS07560 ENOG4108PVD exported protein HF553_RS07570 ENOG4105CV1 Transketolase (EC 2.2.1.1) HF553_RS07575 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HF553_RS07580 ENOG4105C6K Malic enzyme HF553_RS07585 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HF553_RS07590 ENOG4106S4J ethanolamine utilization protein EutP HF553_RS07595 ENOG4105NDK ethanolamine utilization protein HF553_RS07600 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HF553_RS07605 ENOG4108IJ2 phosphate acetyltransferase HF553_RS07610 ENOG4105KNY Microcompartments protein HF553_RS07615 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HF553_RS07620 ENOG4108EKI Dehydrogenase HF553_RS07625 ENOG4107YMV ethanolamine utilization protein HF553_RS07630 ENOG4105C0A alcohol dehydrogenase HF553_RS07635 ENOG4105ENY Ethanolamine utilization protein eutH HF553_RS07640 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HF553_RS07645 ENOG4105CPD ethanolamine ammonia-lyase HF553_RS07655 ENOG4106D67 ethanolamine utilization protein HF553_RS07660 ENOG4108X49 Ethanolamine utilization protein EutK HF553_RS07665 ENOG4108K3Z AraC family transcriptional regulator HF553_RS07675 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HF553_RS07680 ENOG4108R6G acetyltransferase HF553_RS07685 ENOG4105QZU Inner membrane protein YfeZ HF553_RS07690 ENOG4105E7K (LipO)protein HF553_RS07695 ENOG4105EZR dyp-type peroxidase family protein HF553_RS07700 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HF553_RS07705 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HF553_RS07710 ENOG4108I5D sulfate abc transporter HF553_RS07715 ENOG4105ECW sulfate abc transporter HF553_RS07720 ENOG4108IJ6 ABC transporter HF553_RS07725 ENOG4105C6T cysteine synthase HF553_RS07730 ENOG4105M0Y HF553_RS07735 ENOG41089BK Glutamine amido-transferase HF553_RS07740 ENOG4105CSW GntR family transcriptional regulator HF553_RS07745 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HF553_RS07755 ENOG4105C5Y PTS System HF553_RS07760 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HF553_RS07770 ENOG4105C6T cysteine synthase HF553_RS07790 ENOG4105VRT cytoplasmic protein HF553_RS07795 ENOG4105DHU Bile acid HF553_RS07800 ENOG4108M0I Transcriptional regulator HF553_RS07805 ENOG4108NFH Sugar hydrolase HF553_RS07810 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HF553_RS07815 ENOG4105EAA nucleoside HF553_RS07825 ENOG4105CN8 Transcriptional regulator HF553_RS07855 ENOG4105GXM Putative transcription regulator (DUF1323) HF553_RS07860 ENOG4105HZG regulatoR HF553_RS07875 ENOG4108KMM Diguanylate cyclase HF553_RS07880 ENOG4105D9N nucleoside HF553_RS07890 ENOG4109076 Conserved Protein HF553_RS07895 ENOG4105CPC Aldo Keto reductase HF553_RS07900 ENOG4107RA9 decarboxylase HF553_RS07920 ENOG4105CHM Aminotransferase HF553_RS07930 ENOG4105D1S lipid A biosynthesis HF553_RS07935 ENOG4105W9M Membrane HF553_RS07940 ENOG4105CXY transporter HF553_RS07945 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC HF553_RS07955 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta HF553_RS07960 ENOG4108NC2 Outer membrane protease HF553_RS07980 ENOG4105EXC Acyl-transferase HF553_RS07985 ENOG4105CKK Glycosyl transferase, family 2 HF553_RS07990 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) HF553_RS07995 ENOG4108BUD transposase HF553_RS08010 ENOG4105S64 Formate nitrite transporter HF553_RS08015 ENOG410903C (LipO)protein HF553_RS08020 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HF553_RS08025 ENOG4105KZW UPF0381 protein HF553_RS08040 ENOG4108BY2 phosphohistidine phosphatase HF553_RS08050 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) HF553_RS08065 ENOG4105EJ9 Membrane HF553_RS08070 ENOG4108BPE -transporting atpase HF553_RS08075 ENOG4105MH2 YfcL protein HF553_RS08080 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) HF553_RS08085 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HF553_RS08115 ENOG4106WZ1 flagella biosynthesis regulator HF553_RS08125 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HF553_RS08135 ENOG4105DQR SNARE associated Golgi HF553_RS08145 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HF553_RS08150 ENOG4108S3P Sporulation domain protein HF553_RS08155 ENOG4105E96 Colicin v production protein HF553_RS08160 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HF553_RS08165 ENOG4108JUB Transcriptional regulator HF553_RS08175 ENOG4105E5D amino acid HF553_RS08180 ENOG4106M28 alanine racemase domain protein HF553_RS08190 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HF553_RS08195 ENOG4105E89 ABC transporter HF553_RS08200 ENOG4105E89 ABC transporter HF553_RS08205 ENOG4105DSP amino acid AbC transporter HF553_RS08210 ENOG4106YG3 ABC transporter HF553_RS08215 ENOG4108JEH abc transporter atp-binding protein HF553_RS08220 ENOG4105ECP epimerase HF553_RS08225 ENOG4105CYM Glutathione S-transferase HF553_RS08230 ENOG4108SHQ Glutathione S-transferase HF553_RS08235 ENOG4108RE9 Phosphodiesterase HF553_RS08240 ENOG4105PTV Nudix Hydrolase HF553_RS08245 ENOG4105K2J Transcriptional regulator HF553_RS08250 ENOG4106ETB IIa component HF553_RS08260 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HF553_RS08265 ENOG4108HHA Transketolase HF553_RS08270 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) HF553_RS08275 ENOG4105CSX c4-dicarboxylate anaerobic carrier HF553_RS08280 ENOG4105C6K Malic enzyme HF553_RS08285 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HF553_RS08300 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HF553_RS08305 ENOG4107QWE )-transporter HF553_RS08315 ENOG4105CHM Aminotransferase HF553_RS08320 ENOG4107NQ8 LysR family Transcriptional regulator HF553_RS08330 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain HF553_RS08335 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HF553_RS08345 ENOG4105GKE subunit e HF553_RS08350 ENOG4107QIZ NADH dehydrogenase HF553_RS08355 ENOG4108IEH NADH dehydrogenase subunit g HF553_RS08370 ENOG4107UFS subunit j HF553_RS08380 ENOG4105D65 subunit l HF553_RS08385 ENOG4105C8S subunit m HF553_RS08405 ENOG4107YB6 acetyltransferase, (GNAT) family HF553_RS08410 ENOG4105TNS Conserved Protein HF553_RS08415 ENOG4105E4F Isochorismate synthase HF553_RS08430 ENOG4108IPT Naphthoate synthase HF553_RS08440 ENOG4105CEY Amp-dependent synthetase and ligase HF553_RS08445 ENOG4106GZG polymyxin resistance protein B HF553_RS08495 ENOG4108UII YfaZ family HF553_RS08500 ENOG4108EWA cinA-like protein HF553_RS08510 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HF553_RS08520 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HF553_RS08525 ENOG4105CXY transporter HF553_RS08530 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HF553_RS08535 ENOG4105GZI Transcriptional regulator HF553_RS08540 ENOG4105CZM Major Facilitator HF553_RS08545 ENOG4105XPH Ferredoxin HF553_RS08550 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HF553_RS08555 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HF553_RS08590 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HF553_RS08595 ENOG4105BZU Histidine kinase HF553_RS08600 ENOG41068CG regulatoR HF553_RS08605 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HF553_RS08610 ENOG4105FCK Membrane HF553_RS08615 ENOG4105CJ2 (LipO)protein HF553_RS08620 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HF553_RS08625 ENOG4105CF1 Alkylated DNA repair protein HF553_RS08630 ENOG4105IBP Cyclic peptide transporter HF553_RS08640 ENOG4108ZNS ferredoxin-type protein NapF HF553_RS08645 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HF553_RS08655 ENOG4108BGM Quinol dehydrogenase periplasmic component HF553_RS08660 ENOG4105GXZ Ferredoxin-type protein NapH HF553_RS08665 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HF553_RS08670 ENOG4105CUW cytochrome C-TYPE protein HF553_RS08680 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HF553_RS08685 ENOG41060IM Heme exporter protein HF553_RS08690 ENOG4105X3C heme exporter protein HF553_RS08700 ENOG4105DA4 cytochrome c-type biogenesis protein HF553_RS08705 ENOG4107QX9 Thiol disulfide interChange protein HF553_RS08710 ENOG4105KWW Biogenesis protein HF553_RS08715 ENOG4105WH1 Two component transcriptional regulator luxr family HF553_RS08755 ENOG4105E68 Sulfatase HF553_RS08780 ENOG4105CFI type iii restriction protein res subunit HF553_RS08785 ENOG4105I08 Pseudouridine synthase HF553_RS08790 ENOG4105C2C drug resistance transporter, Bcr CflA HF553_RS08795 ENOG4105HG6 HF553_RS08800 ENOG4108JQ5 ABC transporter HF553_RS08805 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HF553_RS08810 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HF553_RS08815 ENOG4105E43 Extracellular solute-binding protein, family 5 HF553_RS08820 ENOG4105CXC rtn protein HF553_RS08825 ENOG4107TT5 NLP P60 protein HF553_RS08830 ENOG41076MN Phosphoesterase, PA-phosphatase related HF553_RS08835 ENOG4105CKI cobalamin synthesis protein HF553_RS08840 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) HF553_RS08845 ENOG4105KRS Proteinase inhibitor HF553_RS08860 ENOG4105S8Q sugar efflux transporter HF553_RS08865 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HF553_RS08870 ENOG4105DE4 1-phosphofructokinase HF553_RS08875 ENOG4105DM4 PTS System HF553_RS08880 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) HF553_RS08885 ENOG4105HMI Membrane HF553_RS08890 ENOG4105DUM transcriptional regulator, lysR family HF553_RS08895 ENOG4108IQI permease HF553_RS08900 ENOG4105D05 Receptor HF553_RS08905 ENOG4105CXY transporter HF553_RS08910 ENOG4105EAC phosphoserine phosphatase HF553_RS08915 ENOG4105EJQ L-serine dehydratase HF553_RS08930 ENOG4105EUJ GTP cyclohydrolase i HF553_RS08935 ENOG4105DHF Membrane HF553_RS08940 ENOG41060NJ transcriptional regulator HF553_RS08945 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HF553_RS08950 ENOG4105C2J ABC transporter HF553_RS08955 ENOG4107SDZ Galactoside transport system permease protein mglC HF553_RS08960 ENOG4107SJI Dehydrogenase HF553_RS08965 ENOG4105BZ8 glutamate synthase HF553_RS08970 ENOG4105Y9N Membrane HF553_RS08975 ENOG4107GZ4 SanA protein HF553_RS08985 ENOG41067MG lrgb family HF553_RS09015 ENOG4108RXX maleylacetoacetate isomerase HF553_RS09020 ENOG4105MSY salicylate hydroxylase HF553_RS09025 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HF553_RS09035 ENOG4105ETP RND efflux system, outer membrane lipoprotein HF553_RS09040 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HF553_RS09045 ENOG4105KHU inner membrane protein YohD HF553_RS09050 ENOG41069YE inner membrane protein yohC HF553_RS09055 ENOG41061WM D-Alanyl-D-Alanine HF553_RS09060 ENOG4105CXG d-lactate dehydrogenase HF553_RS09065 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HF553_RS09070 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HF553_RS09075 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HF553_RS09080 ENOG4108IJ8 ABC transporter HF553_RS09085 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HF553_RS09100 ENOG4108HRK Histidine kinase HF553_RS09105 ENOG4108NEV two component transcriptional regulator, LytTR family HF553_RS09110 ENOG4108W15 Protein of unknown function (DUF1456) HF553_RS09120 ENOG4108YCW (LipO)protein HF553_RS09130 ENOG4105D1F ATP-binding protein HF553_RS09145 ENOG4108MQF Chaperone HF553_RS09150 ENOG4105CW0 outer membrane usher protein HF553_RS09160 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HF553_RS09170 ENOG4105DWF phosphomethylpyrimidine kinase HF553_RS09175 ENOG4105FDP GntR family transcriptional regulator HF553_RS09180 ENOG4108TFM Kinase, PfkB family HF553_RS09185 ENOG4108KD5 ADP-ribosylation crystallin J1 HF553_RS09190 ENOG4105EAA nucleoside HF553_RS09195 ENOG4105EIE fructose-bisphosphate aldolase HF553_RS09210 ENOG41090V3 Tir chaperone protein (CesT) family HF553_RS09220 ENOG4105CFP Peptidase U32 HF553_RS09260 ENOG4105CNA YD repeat protein HF553_RS09265 ENOG4105CNA YD repeat protein HF553_RS09275 ENOG4105NUP lyase containing HEAT-repeat HF553_RS09325 ENOG4105E3W Two component transcriptional regulator (Winged helix family HF553_RS09330 ENOG4105EB3 Histidine kinase HF553_RS09360 ENOG4105R8A Heat shock protein HF553_RS09365 ENOG4105D03 DNA-3-methyladenine glycosylase II HF553_RS09370 ENOG4105BZU Histidine kinase HF553_RS09385 ENOG4108GAE asmA family HF553_RS09390 ENOG4105EE5 Membrane protein terC HF553_RS09395 ENOG4105DAY polysaccharide export protein HF553_RS09400 ENOG4105KJF protein tyrosine phosphatase HF553_RS09405 ENOG4105D75 Capsular exopolysaccharide family HF553_RS09410 ENOG41090RK glycosyl transferase HF553_RS09415 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HF553_RS09420 ENOG4107RXY Glycosyl transferase HF553_RS09425 ENOG4108NYJ Colanic acid HF553_RS09430 ENOG4105ECJ Glycosyl Transferase HF553_RS09435 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HF553_RS09440 ENOG4105C0K Gdp-mannose 4,6-dehydratase HF553_RS09445 ENOG4105C30 Nad-dependent epimerase dehydratase HF553_RS09450 ENOG4105FGF GDP-mannose mannosyl hydrolase HF553_RS09455 ENOG4106CD9 glycosyl transferase group 1 HF553_RS09460 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HF553_RS09465 ENOG4107QKV phosphomannomutase HF553_RS09470 ENOG4105D3Q Sugar transferase HF553_RS09475 ENOG4105PSV Polysaccharide Biosynthesis Protein HF553_RS09480 ENOG4105C74 pyruvyl transferase HF553_RS09485 ENOG4107T8Q Glycosyl transferase (Group 1 HF553_RS09490 ENOG4105G1A colanic acid biosynthesis protein HF553_RS09495 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HF553_RS09500 ENOG4105C1B dTDP-glucose 4-6-dehydratase HF553_RS09505 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase HF553_RS09510 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HF553_RS09515 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase HF553_RS09520 ENOG4107QK7 reductase HF553_RS09525 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase HF553_RS09530 ENOG4105FAW cDP-glucose 4,6-dehydratase HF553_RS09535 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HF553_RS09540 ENOG4108SMP Nad-dependent epimerase dehydratase HF553_RS09545 ENOG4105FB1 Polysaccharide Biosynthesis Protein HF553_RS09550 ENOG4107YYJ Glycosyl transferase, family 2 HF553_RS09555 ENOG4108TJN glycosyl transferase group 1 HF553_RS09560 ENOG4108KBE Glycosyl transferase, family 2 HF553_RS09565 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HF553_RS09570 ENOG4106ECQ phosphomannomutase HF553_RS09575 ENOG4105D3Q Sugar transferase HF553_RS09580 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HF553_RS09585 ENOG4105C6Y Udp-glucose 6-dehydrogenase HF553_RS09590 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HF553_RS09595 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase HF553_RS09610 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HF553_RS09615 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HF553_RS09640 ENOG4107SRH Nad-dependent epimerase dehydratase HF553_RS09645 ENOG4105EQ1 Transcriptional regulator HF553_RS09655 ENOG4105CUB amino acid HF553_RS09660 ENOG4105CJB Exodeoxyribonuclease I HF553_RS09675 ENOG4108J2R molybdopterin oxidoreductase HF553_RS09680 ENOG4105QAX Iron-sulfur HF553_RS09685 ENOG4108NWD Cytochrome HF553_RS09690 ENOG4105DZ1 carboxypeptidase HF553_RS09695 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) HF553_RS09700 ENOG4105DR8 Membrane HF553_RS09705 ENOG41090HJ UPF0265 protein HF553_RS09710 ENOG4105JZC GHMP kinase HF553_RS09715 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HF553_RS09720 ENOG4105KTW ethanolamine utilization protein HF553_RS09725 ENOG4105M3W utilization protein HF553_RS09735 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) HF553_RS09740 ENOG4105C0A alcohol dehydrogenase HF553_RS09745 ENOG4108EKI Dehydrogenase HF553_RS09755 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HF553_RS09765 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) HF553_RS09775 ENOG4105KNY Microcompartments protein HF553_RS09785 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit HF553_RS09790 ENOG4108ZFT Dehydratase small subunit HF553_RS09795 ENOG4105YCI dehydratase medium subunit HF553_RS09800 ENOG4105DMB glycerol dehydratase HF553_RS09805 ENOG4105EHR propanediol utilization protein pduB HF553_RS09810 ENOG4105KNY Microcompartments protein HF553_RS09815 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HF553_RS09820 ENOG4107XVH Transcriptional regulator HF553_RS09825 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) HF553_RS09830 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) HF553_RS09835 ENOG41081F0 Precorrin-8x methylmutase HF553_RS09845 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase HF553_RS09850 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase HF553_RS09855 ENOG4105CIA precorrin-4 C(11)-methyltransferase HF553_RS09860 ENOG4108P62 biosynthesis protein (CbiG) HF553_RS09865 ENOG4105E4R Precorrin-3B C17-methyltransferase HF553_RS09870 ENOG4105QUC reductase HF553_RS09875 ENOG4107PPM cobalt chelatase HF553_RS09880 ENOG4105DVK Precorrin-2 c20-methyltransferase HF553_RS09885 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) HF553_RS09890 ENOG4105W4R Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) HF553_RS09895 ENOG4108V4M Cobalt abc transporter HF553_RS09900 ENOG4108JJB ABC transporter HF553_RS09910 ENOG4108YZT Adenosylcobinamide kinase HF553_RS09925 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HF553_RS09935 ENOG4105UQX Mate efflux family protein HF553_RS09955 ENOG4105HVQ Regulatory factor of maltose metabolism HF553_RS09990 ENOG4105FYV Amp nucleosidase HF553_RS09995 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein HF553_RS10000 ENOG4105KVH Transcriptional regulator HF553_RS10060 ENOG4108YX2 DNA-binding protein HF553_RS10160 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) HF553_RS10170 ENOG4105DFP Integrase HF553_RS10180 ENOG4105KT5 UmuD protein HF553_RS10185 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HF553_RS10200 ENOG4105FCK Membrane HF553_RS10205 ENOG4105Y0K Inner membrane protein YedR HF553_RS10210 ENOG4105EST Metal Dependent Phosphohydrolase HF553_RS10215 ENOG4105DVF Cytosine-specific methyltransferase HF553_RS10220 ENOG41090BB DNA mismatch endonuclease (vsr) HF553_RS10225 ENOG4105FDR Membrane HF553_RS10230 ENOG4105CKW Inner membrane protein yedI HF553_RS10235 ENOG4105VNZ cytoplasmic protein HF553_RS10245 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase HF553_RS10250 ENOG4105YX3 cellular response to acidity HF553_RS10260 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HF553_RS10265 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HF553_RS10270 ENOG4105VS8 Flagellar biosynthetic protein fliq HF553_RS10275 ENOG4105CN7 Flagellar biosynthetic protein FliP HF553_RS10280 ENOG4105K0P flagellar biosynthesis protein HF553_RS10285 ENOG4105DD5 Flagellar motor switch protein HF553_RS10290 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HF553_RS10295 ENOG4107ZI8 flagellar basal body-associated protein flil HF553_RS10300 ENOG4105WF4 Flagellar hook-length control protein HF553_RS10305 ENOG4105GSA Flagellar export protein flij HF553_RS10310 ENOG4108JIR Flagellum-specific ATP synthase HF553_RS10315 ENOG41090PJ Flagellar assembly protein HF553_RS10320 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HF553_RS10325 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HF553_RS10345 ENOG41066VF YeeE YedE family protein HF553_RS10350 ENOG4105JCU Inherit from NOG: (Lipo)protein HF553_RS10355 ENOG4105E5K Alpha-amylase HF553_RS10365 ENOG4105MQ3 flagellar protein FliS HF553_RS10370 ENOG4105DTS flagellar hook-associated HF553_RS10385 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HF553_RS10390 ENOG4108M9K flagella biosynthesis protein FliZ HF553_RS10395 ENOG4105EAB amino acid AbC transporter HF553_RS10405 ENOG4105E5Q amino acid AbC transporter HF553_RS10410 ENOG4105CDA abc transporter atp-binding protein HF553_RS10415 ENOG4105VJY transcriptional regulator HF553_RS10420 ENOG4105XVG cytoplasmic protein HF553_RS10430 ENOG4105WH1 Two component transcriptional regulator luxr family HF553_RS10475 ENOG4106RHG Yeca family HF553_RS10480 ENOG4105E0U tyrosine-specific transport protein HF553_RS10485 ENOG4105VVZ metal-binding protein HF553_RS10490 ENOG41090A1 ferritin HF553_RS10495 ENOG4105P23 (LipO)protein HF553_RS10505 ENOG4108UEC Ferritin-like protein HF553_RS10520 ENOG4108K4C ec 3.1.3.12 HF553_RS10530 ENOG4108VA4 Universal stress protein HF553_RS10545 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HF553_RS10550 ENOG4107RD7 Flagellar Motor Protein, MotA HF553_RS10555 ENOG4105ER2 Ompa motb domain protein HF553_RS10560 ENOG4105CBS Chea signal transduction histidine kinase HF553_RS10565 ENOG4108V3W Chemotaxis protein, CheW HF553_RS10570 ENOG4105C8Q Methyl-accepting chemotaxis HF553_RS10575 ENOG4105BZU Histidine kinase HF553_RS10585 ENOG4108VYJ response regulator receiver protein HF553_RS10590 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HF553_RS10595 ENOG4105D00 flagellar biosynthetic protein flhB HF553_RS10600 ENOG4105D7B Flagellar biosynthesis protein flha HF553_RS10605 ENOG4105IRD Flagellar protein FlhE HF553_RS10610 ENOG4105F5H Glycosyl Hydrolase Family 88 HF553_RS10625 ENOG4106ZCM YecM protein HF553_RS10645 ENOG4105WJG Glutathione HF553_RS10650 ENOG41081XQ Conserved Protein HF553_RS10655 ENOG4105D3W isochorismatase HF553_RS10665 ENOG4108TIT dATP pyrophosphohydrolase HF553_RS10670 ENOG4105CDY transcriptional regulatory protein HF553_RS10680 ENOG4107S01 Repressor protein MetJ HF553_RS10700 ENOG4105FAV ABC, transporter HF553_RS10705 ENOG4105FDK ABC transporter HF553_RS10710 ENOG4105NXV High-affinity zinc uptake system protein HF553_RS10715 ENOG4105DR5 peptidase HF553_RS10720 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HF553_RS10725 ENOG4105CA9 Pyruvate kinase HF553_RS10730 ENOG4106KNT transcriptional regulator HF553_RS10735 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HF553_RS10740 ENOG4105C01 Dihydroxy-acid dehydratase HF553_RS10745 ENOG4108UHU Aldolase HF553_RS10750 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR HF553_RS10755 ENOG4105X2V dna damage-inducible protein HF553_RS10765 ENOG4108Q2J Inner membrane protein YebE HF553_RS10770 ENOG4105CUG Oligopeptidase b HF553_RS10775 ENOG4105UMD exodeoxyribonuclease X HF553_RS10780 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HF553_RS10785 ENOG4105MPK DNA polymerase III subunit theta HF553_RS10790 ENOG4105FXM Copper resistance protein HF553_RS10795 ENOG4108PNC copper resistance HF553_RS10800 ENOG4105NKT exported protein HF553_RS10805 ENOG4108I1J Integrase HF553_RS10870 ENOG41064WM Uncharacterized protein YcgX HF553_RS10875 ENOG4106EWC guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling HF553_RS10885 ENOG4108R1E Serine threonine protein phosphatase 1 HF553_RS10890 ENOG4105UVW uncharacterized protein yebW HF553_RS10895 ENOG4105WT8 Protein of unknown function (DUF1480) HF553_RS10905 ENOG4105DY2 Paraquat-inducible protein b HF553_RS10910 ENOG4105H2K paraquat-inducible protein a HF553_RS10915 ENOG4108ZGC gaf domain protein HF553_RS10925 ENOG4105CN1 protease HF553_RS10930 ENOG4105D0M Protease HtpX homolog HF553_RS10935 ENOG4105C0R drug resistance transporter emrb qaca subfamily HF553_RS10940 ENOG4105J4Q Transcriptional regulator HF553_RS10950 ENOG4106CCY Protein MgrB homolog HF553_RS10955 ENOG4105Q3Y exported protein HF553_RS10970 ENOG4105CJN penicillin-binding protein HF553_RS10975 ENOG4105DHI Methyltransferase HF553_RS10990 ENOG4105F3R pts system mannose fructose sorbose family iid HF553_RS10995 ENOG4105ETZ PTS System HF553_RS11000 ENOG4105DAS pts system HF553_RS11005 ENOG4105EE5 Membrane protein terC HF553_RS11010 ENOG4107XTP (EAL) domain protein HF553_RS11015 ENOG4105EJQ L-serine dehydratase HF553_RS11025 ENOG4105CRQ synthase (Component I) HF553_RS11030 ENOG4105X5C UPF0181 protein HF553_RS11035 ENOG4105M4H endoribonuclease L-psp HF553_RS11040 ENOG4105DVT helicase HF553_RS11045 ENOG41072GX Peptidase M22 Glycoprotease HF553_RS11050 ENOG4105Y4Z Outer Membrane Lipoprotein HF553_RS11055 ENOG4105CEY Amp-dependent synthetase and ligase HF553_RS11060 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HF553_RS11070 ENOG4107QMS site-determining protein HF553_RS11085 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HF553_RS11100 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HF553_RS11110 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) HF553_RS11125 ENOG4105ED1 spovr family HF553_RS11135 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HF553_RS11145 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HF553_RS11155 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HF553_RS11170 ENOG4105D82 Glutamate dehydrogenase HF553_RS11180 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HF553_RS11185 ENOG4105C4M (Ubiquinol oxidase) subunit I HF553_RS11190 ENOG4105MVP hydrogenase-1 operon protein HyaF HF553_RS11195 ENOG4108VXY Hydrogenase-1 operon protein HyaE HF553_RS11200 ENOG4108USZ hydrogenase HF553_RS11205 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HF553_RS11225 ENOG4105C3G gtp-binding protein HF553_RS11235 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HF553_RS11240 ENOG4105CHH sulfate transporter HF553_RS11245 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HF553_RS11260 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) HF553_RS11270 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HF553_RS11275 ENOG4108YY7 Invasion gene expression up-regulator SirB HF553_RS11280 ENOG41063JG Transcriptional regulator HF553_RS11290 ENOG4105EWV Sodium calcium exchanger membrane region HF553_RS11295 ENOG4105WS7 Cation transport regulator HF553_RS11300 ENOG41090EX DsrE family HF553_RS11305 ENOG4105ID0 Putative invasin HF553_RS11310 ENOG4105WH1 Two component transcriptional regulator luxr family HF553_RS11315 ENOG4105BZU Histidine kinase HF553_RS11320 ENOG4105DQQ Major facilitator superfamily MFS_1 HF553_RS11325 ENOG4105CRU nitrate reductase, alpha subunit HF553_RS11330 ENOG4108IUE nitrate reductase beta subunit HF553_RS11335 ENOG4105R3A Nitrate reductase HF553_RS11340 ENOG41076YT nitrate reductase, gamma subunit HF553_RS11370 ENOG4105CIY formyltetrahydrofolate deformylase HF553_RS11380 ENOG4105D78 K07001 NTE family protein HF553_RS11385 ENOG4105I93 response regulator HF553_RS11390 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HF553_RS11405 ENOG4105C0A alcohol dehydrogenase HF553_RS11410 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HF553_RS11415 ENOG4107QSI ABC, transporter HF553_RS11420 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HF553_RS11425 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HF553_RS11430 ENOG4105C3U ABC transporter HF553_RS11435 ENOG4108JQ7 (ABC) transporter HF553_RS11440 ENOG4105EYW Ion transport protein HF553_RS11460 ENOG4105K9H YciI-like protein HF553_RS11465 ENOG410822N TonB family HF553_RS11470 ENOG4105NAU thioesterase Superfamily protein HF553_RS11485 ENOG4105PI0 Ferredoxin HF553_RS11490 ENOG4105EIF outer membrane protein W HF553_RS11495 ENOG4105WEF catalase HF553_RS11500 ENOG4108N8X transition metal ion binding HF553_RS11505 ENOG4108Z9Z response to DNA damage stimulus HF553_RS11525 ENOG4105DK0 Indole-3-glycerol phosphate synthase HF553_RS11530 ENOG4108EFP Anthranilate synthase component II HF553_RS11535 ENOG4105CRQ synthase (Component I) HF553_RS11545 ENOG4105DB7 PHP domain protein HF553_RS11550 ENOG4107RTD sua5 ycio yrdc ywlc family protein HF553_RS11555 ENOG4105FE9 pseudouridine synthase HF553_RS11560 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HF553_RS11565 ENOG4105UBK short-chain dehydrogenase reductase HF553_RS11570 ENOG4105ERU peptidase HF553_RS11575 ENOG4105RKX Protein of unknown function (DUF2498) HF553_RS11580 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HF553_RS11585 ENOG4107R11 Transcriptional regulator HF553_RS11600 ENOG4107QM5 aconitate hydratase HF553_RS11605 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) HF553_RS11610 ENOG4105EYK Phosphatidylglycerophosphatase B HF553_RS11615 ENOG4105Q4A inner membrane protein yciS HF553_RS11620 ENOG4105CFV Tetratricopeptide repeat protein HF553_RS11630 ENOG4108ZJT translation initiation factor, Sui1 HF553_RS11635 ENOG41061RM osmotically inducible lipoprotein HF553_RS11640 ENOG4105N2W Transcriptional regulator HF553_RS11650 ENOG4105BZU Histidine kinase HF553_RS11660 ENOG4105Q4T oxidoreductase HF553_RS11665 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HF553_RS11690 ENOG4108JQ2 peptide transport system atp-binding protein HF553_RS11695 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HF553_RS11700 ENOG4108EU3 peptide transport system, permease HF553_RS11745 ENOG4108EKA peptide transport system, permease HF553_RS11750 ENOG4108J59 Extracellular solute-binding protein, family 5 HF553_RS11755 ENOG4105E51 psp operon transcriptional activator HF553_RS11760 ENOG41087YS Phage shock protein A HF553_RS11765 ENOG4105YYT phage shock protein B HF553_RS11770 ENOG4105FM1 phage shock protein C HF553_RS11775 ENOG4105NNG Peripheral inner membrane phage-shock protein HF553_RS11780 ENOG4105K8Z Phage shock protein HF553_RS11785 ENOG4105CM6 amino acid regulated cytosolic protein HF553_RS11795 ENOG4108JU8 Transcriptional regulator HF553_RS11800 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HF553_RS11805 ENOG4107S8C mandelate racemase muconate lactonizing HF553_RS11810 ENOG4105KXI murein peptide amidase A HF553_RS11815 ENOG4107QSI ABC, transporter HF553_RS11825 ENOG4105HEI LysR family (Transcriptional regulator HF553_RS11830 ENOG4105CV8 reductase HF553_RS11835 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HF553_RS11840 ENOG4108XFH Transcriptional regulator HF553_RS11855 ENOG4106PHM regulatory protein HF553_RS11875 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HF553_RS11895 ENOG4105D64 Mechanosensitive ion channel HF553_RS11900 ENOG4105S5I Membrane HF553_RS11905 ENOG4105Q9Y Universal stress protein HF553_RS11910 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HF553_RS11915 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HF553_RS11920 ENOG4108DG9 Smr protein MutS2 HF553_RS11925 ENOG4105C8Q Methyl-accepting chemotaxis HF553_RS11935 ENOG4105C1J atp-dependent rna helicase HF553_RS11955 ENOG410814C multidrug resistance protein HF553_RS11960 ENOG4108RW8 Universal stress protein F HF553_RS11965 ENOG4108RS6 transposase HF553_RS11970 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HF553_RS11980 ENOG4105IKK cytoplasmic protein HF553_RS11985 ENOG41090X5 Heat shock protein hslJ HF553_RS11990 ENOG4105C5I Dehydrogenase HF553_RS11995 ENOG4107H52 Dicarboxylate transport HF553_RS12000 ENOG410689M (LipO)protein HF553_RS12005 ENOG4105WXT Conserved Protein HF553_RS12020 ENOG4105CQ7 ATP-dependent helicase HF553_RS12025 ENOG4107DB1 DUF218 domain HF553_RS12030 ENOG4105CPW cytochrome b561 HF553_RS12035 ENOG4108WF3 methyltransferase HF553_RS12045 ENOG4105E5Q amino acid AbC transporter HF553_RS12055 ENOG4105E5Q amino acid AbC transporter HF553_RS12060 ENOG4107R0W ABC transporter HF553_RS12070 ENOG4107ZUJ lipid metabolic process HF553_RS12095 ENOG4105C8Q Methyl-accepting chemotaxis HF553_RS12100 ENOG4105DDW LysR family Transcriptional regulator HF553_RS12105 ENOG4105E32 cytoplasmic protein HF553_RS12110 ENOG4105EBR Carboxylesterase HF553_RS12115 ENOG4105DJ9 glucan biosynthesis protein HF553_RS12125 ENOG4105DT3 PTS system, galactitol-specific IIc component HF553_RS12130 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HF553_RS12135 ENOG4105CN9 Peptidase m42 family protein HF553_RS12140 ENOG4108Z9I -acetyltransferase HF553_RS12145 ENOG4107WE3 acetyltransferase YdcK HF553_RS12150 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HF553_RS12155 ENOG41088CC tellurite resistance protein tehB HF553_RS12160 ENOG4108KKZ (LipO)protein HF553_RS12165 ENOG4105DKK Benzoate HF553_RS12170 ENOG4108JCI Transcriptional regulator HF553_RS12175 ENOG4105CFP Peptidase U32 HF553_RS12180 ENOG4105RR0 Protein of unknown function (DUF2554) HF553_RS12200 ENOG4108UQS dipeptidase HF553_RS12205 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HF553_RS12220 ENOG410654E Membrane HF553_RS12240 ENOG4105R71 cytoplasmic protein HF553_RS12245 ENOG4108T9Y Inner membrane protein ydcZ HF553_RS12250 ENOG4108Z7F N-acetyltransferase HF553_RS12255 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein HF553_RS12260 ENOG4108WYP Transcriptional regulator HF553_RS12265 ENOG4105CHB tonB-dependent Receptor HF553_RS12270 ENOG4108NS2 receptor HF553_RS12275 ENOG4105SUV lipoprotein YgdR HF553_RS12280 ENOG4105C85 amino acid HF553_RS12290 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HF553_RS12295 ENOG4105JAB phenazine biosynthesis protein, phzf family HF553_RS12300 ENOG4105D0D Nitrate reductase 2, gamma subunit HF553_RS12305 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HF553_RS12310 ENOG4108IUE nitrate reductase beta subunit HF553_RS12315 ENOG4105CRU nitrate reductase, alpha subunit HF553_RS12320 ENOG4107QND Nitrite extrusion protein HF553_RS12355 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HF553_RS12360 ENOG4108MG3 formate dehydrogenase HF553_RS12365 ENOG4105DQ4 alcohol dehydrogenase HF553_RS12380 ENOG4105TPS biofilm-dependent modulation protein HF553_RS12385 ENOG4108Z9K Osmotically inducible protein HF553_RS12390 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells HF553_RS12400 ENOG4105XXV Acid-resistance protein HF553_RS12410 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) HF553_RS12425 ENOG4105C87 Aminotransferase class I and II HF553_RS12430 ENOG4105DFD Na H antiporter HF553_RS12435 ENOG41060NJ transcriptional regulator HF553_RS12470 ENOG4108UQ8 endoribonuclease L-psp HF553_RS12475 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) HF553_RS12500 ENOG4108I5G Major Facilitator superfamily HF553_RS12505 ENOG4105CPQ Dehydrogenase HF553_RS12510 ENOG4105C6F GntR Family Transcriptional Regulator HF553_RS12525 ENOG4105DPX Hydrogenase, large subunit HF553_RS12530 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HF553_RS12550 ENOG4105MVP hydrogenase-1 operon protein HyaF HF553_RS12575 ENOG4105FFC UPF0187 protein HF553_RS12580 ENOG4105M0C cytoplasmic protein HF553_RS12590 ENOG4105C26 Dehydrogenase HF553_RS12595 ENOG4105EGI Transcriptional regulator HF553_RS12610 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HF553_RS12615 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HF553_RS12620 ENOG4106DNR multiple antibiotic resistance protein HF553_RS12625 ENOG4108594 Permease of the drug metabolite transporter HF553_RS12630 ENOG4105E5W Transporter HF553_RS12640 ENOG4108YDI single-species biofilm formation on inanimate substrate HF553_RS12645 ENOG4108WTK competence damage-inducible protein HF553_RS12655 ENOG4105DGW oligopeptidase A HF553_RS12660 ENOG4105EMU Dehydrogenase HF553_RS12665 ENOG4107XBN GntR Family Transcriptional Regulator HF553_RS12670 ENOG41061EV selenium-binding protein YdfZ HF553_RS12675 ENOG4105DEI Mannitol dehydrogenase HF553_RS12685 ENOG4105CPQ Dehydrogenase HF553_RS12705 ENOG4108MK9 spermidine N(1)-acetyltransferase HF553_RS12715 ENOG4105KBG Protein of unknown function (DUF1161) HF553_RS12720 ENOG4107QY8 reductase HF553_RS12725 ENOG4105C3J Cysteine desulfurase HF553_RS12730 ENOG4105QAX Iron-sulfur HF553_RS12735 ENOG4107KGK dmso reductase anchor subunit HF553_RS12740 ENOG4108NEM leader-binding protein dmsD HF553_RS12745 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component HF553_RS12750 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HF553_RS12755 ENOG4105E90 ABC transporter HF553_RS12760 ENOG4108IJ8 ABC transporter HF553_RS12770 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HF553_RS12775 ENOG4105DAG ROK family HF553_RS12780 ENOG4106NZI LysR family Transcriptional regulator HF553_RS12785 ENOG4105D94 Major Facilitator Superfamily HF553_RS12795 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HF553_RS12815 ENOG4105DSF transport protein HF553_RS12820 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HF553_RS12825 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HF553_RS12830 ENOG4105C5D exported protein HF553_RS12835 ENOG4105D5Q Arginine ornithine antiporter HF553_RS12840 ENOG4105RA2 Membrane HF553_RS12845 ENOG4107EXC regulatoR HF553_RS12850 ENOG4105FCK Membrane HF553_RS12855 ENOG4105CPN adenine deaminase HF553_RS12860 ENOG4105JJR Histidine kinase HF553_RS12870 ENOG4105C9Q fumarate hydratase class II HF553_RS12875 ENOG4107GFK fumarate HF553_RS12880 ENOG4105EIP mannose-6-phosphate isomerase HF553_RS12885 ENOG4106J39 exported protein HF553_RS12900 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) HF553_RS12905 ENOG4105D9R oxidoreductase HF553_RS12910 ENOG4106C6R beta-lactam resistance protein HF553_RS12920 ENOG4105M9B inner membrane protein ydgK HF553_RS12945 ENOG4108UQQ Electron transport complex HF553_RS12955 ENOG4105CSM endonuclease III HF553_RS12960 ENOG4105DUX Transporter HF553_RS12965 ENOG4108K3A Glutathione S-transferase HF553_RS12985 ENOG410642K Lysozyme inhibitor HF553_RS12995 ENOG4108XTF Outer Membrane Lipoprotein HF553_RS13010 ENOG4105Y49 secretion protein, HlyD family HF553_RS13015 ENOG4105DSW Fusaric acid resistance protein HF553_RS13020 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HF553_RS13025 ENOG4107RGM aldo keto reductase HF553_RS13030 ENOG4105XZD Fe-S protein HF553_RS13035 ENOG4108WUH Transcriptional regulator, TetR family HF553_RS13040 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HF553_RS13045 ENOG4108UYE Lactoylglutathione lyase HF553_RS13050 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) HF553_RS13055 ENOG4105M2J Glutaredoxin HF553_RS13060 ENOG4105K4H Nlp p60 protein HF553_RS13065 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HF553_RS13080 ENOG4105F52 Transcriptional regulator HF553_RS13085 ENOG4105CZQ inner membrane transport protein YdhC HF553_RS13090 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HF553_RS13095 ENOG4108R6K riboflavin synthase, subunit alpha HF553_RS13115 ENOG4108IUF type iii secretion HF553_RS13120 ENOG4108TN6 type iii secretion HF553_RS13125 ENOG41083GP type iii secretion HF553_RS13130 ENOG4108HHI Type III secretion system protein HF553_RS13135 ENOG41063Q7 Type III secretion system protein HF553_RS13150 ENOG4108JIR Flagellum-specific ATP synthase HF553_RS13160 ENOG4106H1D secretion system apparatus protein HF553_RS13165 ENOG4105UQF type iii secretion HF553_RS13170 ENOG4106563 type III secretion system apparatus protein HF553_RS13220 ENOG4106FZW pathogenicity island effector protein HF553_RS13225 ENOG4108SZ7 secretion system effector HF553_RS13235 ENOG4105ZQI secreted protein HF553_RS13265 ENOG4105BZU Histidine kinase HF553_RS13275 ENOG4108XDN Transcriptional regulator HF553_RS13280 ENOG4107SEY Conserved Protein HF553_RS13285 ENOG4105RFR Protein of unknown function (DUF2767) HF553_RS13290 ENOG4108ZXC Two component transcriptional regulator, luxr family HF553_RS13295 ENOG4106AFQ Histidine kinase HF553_RS13300 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HF553_RS13305 ENOG4106WHD Tetrathionate reductase HF553_RS13310 ENOG4105DB1 molybdopterin oxidoreductase HF553_RS13315 ENOG4108RVA ribokinase HF553_RS13325 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) HF553_RS13330 ENOG4105CUB amino acid HF553_RS13335 ENOG4105CA9 Pyruvate kinase HF553_RS13355 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HF553_RS13370 ENOG4105JRK feS assembly protein SufD HF553_RS13375 ENOG4105C3K feS assembly ATPase SufC HF553_RS13380 ENOG4105DIW FeS assembly protein SUFB HF553_RS13385 ENOG4108Z4V iron-sulfur cluster assembly HF553_RS13390 ENOG4108ETY sodium dicarboxylate symporter HF553_RS13395 ENOG410671Z uncharacterized protein ydiH HF553_RS13400 ENOG4105KA0 thioesterase Superfamily protein HF553_RS13405 ENOG4105CQB FAD linked oxidase domain protein HF553_RS13420 ENOG4105SUA Ydil protein HF553_RS13425 ENOG4105EMV Major Facilitator HF553_RS13430 ENOG4105EMV Major Facilitator HF553_RS13445 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HF553_RS13450 ENOG4105C1G acyl-Coa dehydrogenase HF553_RS13455 ENOG4105W4W Transcriptional regulator HF553_RS13460 ENOG4105CV7 Electron transfer flavoprotein HF553_RS13465 ENOG4105C10 Electron transfer flavoprotein HF553_RS13470 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HF553_RS13475 ENOG41090P5 ferredoxin-like protein HF553_RS13480 ENOG4105CEY Amp-dependent synthetase and ligase HF553_RS13485 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HF553_RS13495 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HF553_RS13520 ENOG4108QBX (LipO)protein HF553_RS13530 ENOG4108V06 Glutathione peroxidase HF553_RS13540 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) HF553_RS13545 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) HF553_RS13565 ENOG41082NX 50s ribosomal protein l35 HF553_RS13570 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HF553_RS13580 ENOG4105K25 O-Antigen polymerase HF553_RS13605 ENOG4108NE3 Salt-induced outer membrane protein HF553_RS13610 ENOG4105DE4 1-phosphofructokinase HF553_RS13615 ENOG4105P10 Uncharacterized protein ydiZ HF553_RS13625 ENOG4107PN8 YfeABCD locus regulator HF553_RS13630 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HF553_RS13635 ENOG4107K5X Membrane-bound metal-dependent hydrolase HF553_RS13640 ENOG4108ETY sodium dicarboxylate symporter HF553_RS13650 ENOG4105CH6 catalase HF553_RS13660 ENOG4105F8D glycoside hydrolase family 4 HF553_RS13665 ENOG4105EZV Transcriptional regulator HF553_RS13670 ENOG4105VCP PTS System HF553_RS13675 ENOG4105CK1 PTS System HF553_RS13680 ENOG4105VZJ PTS System HF553_RS13685 ENOG4105KKI DNA-binding transcriptional activator OsmE HF553_RS13695 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HF553_RS13700 ENOG4108SPG Periplasmic Protein HF553_RS13715 ENOG4105C26 Dehydrogenase HF553_RS13730 ENOG4105CGK Exodeoxyribonuclease III HF553_RS13735 ENOG4105M6F mutator MutT protein HF553_RS13740 ENOG4105MTM Protein of unknown function (DUF1496) HF553_RS13745 ENOG4105D82 Glutamate dehydrogenase HF553_RS13750 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HF553_RS13755 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) HF553_RS13760 ENOG41069NU Nitroreductase HF553_RS13765 ENOG4105D07 Signal peptide peptidase, SppA HF553_RS13770 ENOG4105HDK L-asparaginase HF553_RS13775 ENOG4108RWI nicotinamidase HF553_RS13780 ENOG4105VUT cytoplasmic protein HF553_RS13790 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HF553_RS13795 ENOG4105DSB aldose 1-epimerase HF553_RS13800 ENOG4105CV8 reductase HF553_RS13805 ENOG4105C4X radical SAM domain protein HF553_RS13810 ENOG4105GNX MltA-interacting MipA family protein HF553_RS13815 ENOG4105CYN Serine protein kinase HF553_RS13830 ENOG4108KHP Diguanylate cyclase HF553_RS13835 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HF553_RS13850 ENOG4105R1U AraC Family Transcriptional Regulator HF553_RS13855 ENOG4105DJ2 Major Facilitator Superfamily HF553_RS13860 ENOG4105K78 MarR family Transcriptional regulator HF553_RS13870 ENOG4105UCG Domain of unknown function (DUF333) HF553_RS13875 ENOG4106G4W HF553_RS13880 ENOG4105Y3U Transglycosylase-associated protein HF553_RS13890 ENOG4105YP6 Domain of unknown function (DUF1869) HF553_RS13895 ENOG4108YS1 cytoplasmic protein HF553_RS13905 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) HF553_RS13920 ENOG4108Z6Z Transcriptional regulator HF553_RS13935 ENOG4108MEK Metal-binding protein YodA HF553_RS13950 ENOG4105D64 Mechanosensitive ion channel HF553_RS13955 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HF553_RS13960 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HF553_RS13985 ENOG4108VKM cytochrome b561 HF553_RS13995 ENOG4108ZNX Heat shock protein HF553_RS14020 ENOG4105H38 Membrane HF553_RS14030 ENOG41060EU Cold shock-like protein HF553_RS14035 ENOG4106F2Y RICIN HF553_RS14040 ENOG4105Y50 Virulence Protein HF553_RS14045 ENOG4108TMH cytolethal distending toxin HF553_RS14075 ENOG4108RS6 transposase HF553_RS14080 ENOG4108HMX isocitrate dehydrogenase (NADP) HF553_RS14090 ENOG4105Y9F tail fiber protein HF553_RS14095 ENOG4105Y0G tail protein HF553_RS14100 ENOG4108T86 baseplate J family protein HF553_RS14145 ENOG4105TKZ Tail Sheath HF553_RS14190 ENOG4105EFC phage portal protein HK97 family HF553_RS14200 ENOG4105CAR Terminase, large subunit HF553_RS14240 ENOG4105HGD Antitermination protein HF553_RS14245 ENOG4108MXB Protein of unknown function (DUF968) HF553_RS14255 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) HF553_RS14260 ENOG4105DFE Dna adenine methylase HF553_RS14280 ENOG4106050 phage regulatory protein, rha family HF553_RS14285 ENOG4108S1U HF553_RS14300 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) HF553_RS14310 ENOG4105H40 HF553_RS14315 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) HF553_RS14320 ENOG4108R7K Metal Dependent Phosphohydrolase HF553_RS14350 ENOG4108I1J Integrase HF553_RS14355 ENOG4108HMX isocitrate dehydrogenase (NADP) HF553_RS14360 ENOG4108R99 pseudouridine synthase HF553_RS14385 ENOG4107QTF adenylosuccinate lyase HF553_RS14400 ENOG4105EZE Cupin 4 family protein HF553_RS14415 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HF553_RS14430 ENOG4105D38 putrescine abc transporter HF553_RS14435 ENOG4108HM4 ABC transporter HF553_RS14440 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HF553_RS14450 ENOG4105D60 lipoprotein releasing system transmembrane protein HF553_RS14455 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HF553_RS14460 ENOG4105D60 lipoprotein releasing system transmembrane protein HF553_RS14465 ENOG4108JA2 transcriptioN-repair coupling factor HF553_RS14470 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HF553_RS14475 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HF553_RS14480 ENOG4108IND Tetr family transcriptional regulator HF553_RS14485 ENOG4107MBR 17 kDa surface antigen HF553_RS14490 ENOG4105CEP NADH dehydrogenase HF553_RS14510 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HF553_RS14515 ENOG41090DQ Lipoprotein HF553_RS14520 ENOG4105K59 histidine triad (HIT) protein HF553_RS14525 ENOG4105CNM Receptor HF553_RS14530 ENOG4105CI1 PTS System HF553_RS14535 ENOG4105F8V Hydrolase, tatD family HF553_RS14540 ENOG4107QRG dna polymerase iii HF553_RS14550 ENOG4105HHA aminodeoxychorismate lyase HF553_RS14555 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HF553_RS14560 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HF553_RS14565 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HF553_RS14570 ENOG4105CHR reductase HF553_RS14575 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HF553_RS14580 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) HF553_RS14595 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HF553_RS14605 ENOG4105EI2 Pseudouridine synthase HF553_RS14610 ENOG4107QQB Ribonuclease E HF553_RS14615 ENOG4105DTJ flagellar hook-associated protein HF553_RS14620 ENOG4105E1Q flagellar hook-associated protein HF553_RS14625 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HF553_RS14640 ENOG4105CGA flagellar basal-body rod protein FlgG HF553_RS14645 ENOG4108KPB Flagellar basal-body rod protein FlgF HF553_RS14650 ENOG4105BZE flagellar hook protein, FlgE HF553_RS14655 ENOG4105W00 Flagellar hook capping protein HF553_RS14660 ENOG4108ZC9 flagellar basal-body rod protein flgc HF553_RS14665 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HF553_RS14670 ENOG4105CKS Flagella basal body P-ring formation protein flgA HF553_RS14675 ENOG4105M9M anti-sigma28 factor FlgM HF553_RS14680 ENOG4105QVD Flagella synthesis protein FlgN HF553_RS14685 ENOG4105CJR Integral membrane protein (MviN HF553_RS14700 ENOG4105D9U N-acetyltransferase HF553_RS14710 ENOG4105E9S glutaredoxin 2 HF553_RS14715 ENOG4105F3T (LipO)protein HF553_RS14725 ENOG4105MEA DNA damage-inducible protein i HF553_RS14730 ENOG4105PVA Biofilm formation regulatory protein BssS HF553_RS14740 ENOG4106974 biofilm formation HF553_RS14745 ENOG4105DS1 cytochrome b561 HF553_RS14750 ENOG4108YYC ycei family HF553_RS14760 ENOG4105D1S lipid A biosynthesis HF553_RS14770 ENOG4108W47 Acidic protein msyB HF553_RS14775 ENOG4105NAC (LipO)protein HF553_RS14780 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HF553_RS14790 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) HF553_RS14795 ENOG4107RZC phospholipase d HF553_RS14800 ENOG4108UVJ appr-1-p processing domain protein HF553_RS14805 ENOG41068SS HF553_RS14810 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) HF553_RS14815 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin HF553_RS14820 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HF553_RS14825 ENOG41086KC Transcriptional regulator HF553_RS14830 ENOG4108XDW curli assembly protein CsgE HF553_RS14835 ENOG4108WYR Curli production assembly transport component, CsgF HF553_RS14840 ENOG4105P8Q Curli production assembly transport component CsgG HF553_RS14845 ENOG4108RS6 transposase HF553_RS14850 ENOG4108UQ5 membrane protein YcdZ HF553_RS14855 ENOG4107XHZ cytoplasmic chaperone TorD family protein HF553_RS14930 ENOG4107RJ5 oxidoreductase HF553_RS14935 ENOG4105JHE Major Facilitator Superfamily HF553_RS14940 ENOG4108QGT oligogalacturonate-specific porin HF553_RS14950 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) HF553_RS14955 ENOG4107RJ1 sodium solute HF553_RS14960 ENOG4105QEK Transcriptional regulator HF553_RS14965 ENOG4105D5M phosphate starvation-inducible protein HF553_RS14970 ENOG4105CK7 Sodium proline symporter HF553_RS14985 ENOG4108R86 Transcriptional regulator HF553_RS14990 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HF553_RS14995 ENOG4105CS1 NAD(P)H quinone oxidoreductase HF553_RS15000 ENOG4105XH3 HF553_RS15005 ENOG4105D6F Phosphatase HF553_RS15010 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HF553_RS15015 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) HF553_RS15020 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) HF553_RS15075 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase HF553_RS15080 ENOG4105C26 Dehydrogenase HF553_RS15090 ENOG4108V8F Transcriptional regulator, MarR family HF553_RS15095 ENOG4105EFA 4-hydroxyphenylacetate HF553_RS15100 ENOG4107UWN reductase HF553_RS15105 ENOG4105VT2 5-hydroxyisourate hydrolase HF553_RS15110 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HF553_RS15115 ENOG4107ZY3 Histidine kinase HF553_RS15130 ENOG4106YSC HF553_RS15135 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell HF553_RS15140 ENOG4106HNN Invasion protein HF553_RS15150 ENOG41084BJ Pentapeptide repeat protein HF553_RS15165 ENOG4108MN8 Membrane HF553_RS15175 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HF553_RS15185 ENOG4108V1U phospholipid-binding protein HF553_RS15200 ENOG4105K4P CoA-binding domain protein HF553_RS15210 ENOG4108Z5K methylglyoxal synthase HF553_RS15215 ENOG41088T4 Helicase IV HF553_RS15220 ENOG410901E Membrane HF553_RS15225 ENOG4105EM2 membrane HF553_RS15230 ENOG4108RZ1 DNA transformation protein HF553_RS15240 ENOG4105UYK outer membrane protein a HF553_RS15250 ENOG4105DAN ATP-dependent protease HF553_RS15260 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HF553_RS15265 ENOG4108Q2G (LipO)protein HF553_RS15270 ENOG4105DY2 Paraquat-inducible protein b HF553_RS15275 ENOG4105F1S paraquat-inducible protein a HF553_RS15280 ENOG4105C5H ABC transporter HF553_RS15290 ENOG4105QVC MOSC domain-containing protein HF553_RS15295 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HF553_RS15305 ENOG4105CD8 aminopeptidase N HF553_RS15315 ENOG4105C5S asparaginyl-tRNA synthetase HF553_RS15320 ENOG4105FCK Membrane HF553_RS15325 ENOG4105CGF Aromatic amino acid aminotransferase HF553_RS15330 ENOG4105C5X domain protein HF553_RS15335 ENOG4105EAQ (twin-arginine translocation) pathway signal HF553_RS15340 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HF553_RS15350 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HF553_RS15360 ENOG4106371 Methyltransferase HF553_RS15365 ENOG4107S90 membrAne HF553_RS15370 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HF553_RS15385 ENOG4105T0Z Conserved Protein HF553_RS15395 ENOG4105BZ1 (ABC) transporter HF553_RS15400 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HF553_RS15405 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) HF553_RS15410 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HF553_RS15420 ENOG4108K0D peptidase, M48 HF553_RS15435 ENOG4107VMU Membrane HF553_RS15440 ENOG4105DDY UPF0142 protein ycaO HF553_RS15445 ENOG4105TMB Formate nitrite transporter HF553_RS15450 ENOG4105C6N Formate acetyltransferase HF553_RS15455 ENOG4108RS6 transposase HF553_RS15460 ENOG4105GUS HF553_RS15465 ENOG4105F1A Pyruvate formate-lyase HF553_RS15470 ENOG4105E5D amino acid HF553_RS15480 ENOG4107KGK dmso reductase anchor subunit HF553_RS15485 ENOG4105QAX Iron-sulfur HF553_RS15490 ENOG4107QY8 reductase HF553_RS15500 ENOG4105D1H recombination factor protein RarA HF553_RS15510 ENOG4105CNU cell division protein FtsK HF553_RS15515 ENOG4105EW9 transcriptional regulator AsnC family HF553_RS15520 ENOG4105C3M thioredoxin reductase HF553_RS15525 ENOG4108JJ9 ABC, transporter HF553_RS15530 ENOG4108JJ8 (ABC) transporter HF553_RS15545 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HF553_RS15550 ENOG4105HEI LysR family (Transcriptional regulator HF553_RS15555 ENOG4105EUB pirin domain protein HF553_RS15560 ENOG4105CHJ isochorismatase hydrolase HF553_RS15580 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HF553_RS15590 ENOG4105VEQ Cold shock protein HF553_RS15595 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HF553_RS15600 ENOG4105DJY efflux transporter, rnd family, mfp subunit HF553_RS15605 ENOG4108MJ5 VirK protein HF553_RS15610 ENOG4105CPB ATP-dependent endonuclease of the OLD family HF553_RS15615 ENOG4105DWU Membrane HF553_RS15625 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HF553_RS15630 ENOG4105C7K acetolactate synthase HF553_RS15635 ENOG4105C5W Aldolase HF553_RS15640 ENOG4105CGD Nad-dependent epimerase dehydratase HF553_RS15645 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HF553_RS15650 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HF553_RS15660 ENOG41064MM (LipO)protein HF553_RS15665 ENOG4105E5Z arginine transporter ATP-binding subunit HF553_RS15670 ENOG4106PMH Extracellular solute-binding protein family 3 HF553_RS15675 ENOG4105GBT ABC transporter HF553_RS15680 ENOG4105DMR ABC, transporter HF553_RS15685 ENOG4106TNF Periplasmic binding protein HF553_RS15710 ENOG4105RBQ inner membrane protein ybjO HF553_RS15715 ENOG4105D38 putrescine abc transporter HF553_RS15720 ENOG4105F38 ABC transporter, permease HF553_RS15725 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HF553_RS15730 ENOG4107RUE extracellular solute-binding protein family 1 HF553_RS15735 ENOG4108RMJ sensory transduction regulator HF553_RS15745 ENOG4108DBC nitroreductase HF553_RS15750 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HF553_RS15755 ENOG41090BQ Glutaredoxin HF553_RS15760 ENOG4105GWF inner membrane protein YbjM HF553_RS15770 ENOG4108RFG Tetr family transcriptional regulator HF553_RS15775 ENOG4106UW1 Major Facilitator superfamily HF553_RS15780 ENOG4108HCJ Hydrolase HF553_RS15785 ENOG4107QF7 multi-drug HF553_RS15790 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HF553_RS15795 ENOG4107FB0 transcriptional regulator DeoR family HF553_RS15800 ENOG4105DZ1 carboxypeptidase HF553_RS15805 ENOG4108TGY Glutathione S-transferase HF553_RS15810 ENOG4105D8V Glucose sorbosone dehydrogenase HF553_RS15815 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HF553_RS15830 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HF553_RS15835 ENOG4105DEF Extracellular solute-binding protein, family 5 HF553_RS15840 ENOG4108JQ6 ABC transporter HF553_RS15845 ENOG4105D44 asparaginase HF553_RS15850 ENOG4105CVM Molybdenum cofactor synthesis domain protein HF553_RS15855 ENOG4105D06 uba thif-type nad fad binding protein HF553_RS15860 ENOG4105F1A Pyruvate formate-lyase HF553_RS15870 ENOG4108HCJ Hydrolase HF553_RS15875 ENOG41072TH Protein of unknown function (DUF1479) HF553_RS15880 ENOG4105C5H ABC transporter HF553_RS15885 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HF553_RS15890 ENOG4105F4P )-transporter HF553_RS15895 ENOG4105KST dependent repressor HF553_RS15905 ENOG4108I6E Sulfatase HF553_RS15910 ENOG4108T1M outer membrane protein x HF553_RS15925 ENOG4107R0W ABC transporter HF553_RS15930 ENOG4105E5Q amino acid AbC transporter HF553_RS15935 ENOG4105CDA abc transporter atp-binding protein HF553_RS15940 ENOG4105D8X mechanosensitive ion channel HF553_RS15950 ENOG4105KSC Transcriptional regulator, TraR DksA family HF553_RS15955 ENOG4105VR4 UPF0379 protein ybiJ HF553_RS15960 ENOG4108MTB glycosyl transferase family HF553_RS15965 ENOG4105DVT helicase HF553_RS15970 ENOG4105C1J atp-dependent rna helicase HF553_RS15975 ENOG4107MVR Transcriptional regulator HF553_RS15980 ENOG4105D0S secretion protein (HlyD HF553_RS15985 ENOG4105CJ1 ABC, transporter HF553_RS15990 ENOG4107QWP ABC-2 type transporter HF553_RS15995 ENOG4107QWP ABC-2 type transporter HF553_RS16000 ENOG4105I9U inner membrane protein ybhQ HF553_RS16005 ENOG4105X23 Endonuclease Exonuclease phosphatase HF553_RS16010 ENOG4105DZQ phospholipase D Transphosphatidylase HF553_RS16015 ENOG4107UXM Membrane HF553_RS16030 ENOG4105HFZ Membrane HF553_RS16035 ENOG4108ZAF Molybdopterin HF553_RS16040 ENOG4105M00 molybdopterin converting factor, subunit 1 HF553_RS16050 ENOG4108RIR Molybdenum cofactor biosynthesis protein HF553_RS16060 ENOG4105CHW UPF0052 protein HF553_RS16075 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HF553_RS16080 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HF553_RS16095 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HF553_RS16100 ENOG4108V1U phospholipid-binding protein HF553_RS16130 ENOG4105NBR Pectinesterase HF553_RS16140 ENOG4108K4B hydrolase HF553_RS16150 ENOG4105E0C molybdate abc transporter HF553_RS16155 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HF553_RS16165 ENOG4105F4R Transcriptional regulator mode HF553_RS16170 ENOG4105DKW ABC transporter HF553_RS16180 ENOG4105CMR udp-glucose 4-epimerase HF553_RS16185 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HF553_RS16195 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HF553_RS16205 ENOG4105E0A ABC, transporter HF553_RS16210 ENOG4105EHG Permease protein HF553_RS16215 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase HF553_RS16220 ENOG4105D9Q decarboxylase (Beta subunit) HF553_RS16225 ENOG4107QSA Oxaloacetate decarboxylase HF553_RS16230 ENOG4106AFN Lyase and sodium transporter (By similarity) HF553_RS16235 ENOG4107QWE )-transporter HF553_RS16245 ENOG4105C5Q Transcriptional regulator HF553_RS16255 ENOG4107GFK fumarate HF553_RS16260 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HF553_RS16265 ENOG4105JND homeobox protein HF553_RS16270 ENOG4105PGM cation diffusion facilitator family transporter HF553_RS16275 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HF553_RS16315 ENOG4105UFD tol-pal system protein YbgF HF553_RS16320 ENOG4105KCK Peptidoglycan-associated lipoprotein HF553_RS16330 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HF553_RS16340 ENOG4105E02 MotA TolQ exbB proton channel HF553_RS16345 ENOG4107YD3 Thioesterase HF553_RS16350 ENOG4105KJB cyd operon protein YbgE HF553_RS16360 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HF553_RS16365 ENOG4105C4M (Ubiquinol oxidase) subunit I HF553_RS16370 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HF553_RS16380 ENOG4105C7S Dehydrogenase HF553_RS16385 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HF553_RS16390 ENOG4105E33 succinate dehydrogenase HF553_RS16395 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HF553_RS16400 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HF553_RS16405 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HF553_RS16415 ENOG4105BZN citrate synthase HF553_RS16420 ENOG4108KK1 membrane protein AbrB duplication HF553_RS16435 ENOG4107R7A Allophanate hydrolase subunit 2 HF553_RS16440 ENOG4105P4J Allophanate hydrolase, subunit 1 HF553_RS16445 ENOG4107QNR UPF0135 protein HF553_RS16455 ENOG4105CVP deoxyribo-dipyrimidine photolyase HF553_RS16460 ENOG4105XIQ Protein of unknown function (DUF2517) HF553_RS16485 ENOG4105C08 Histidine kinase HF553_RS16490 ENOG4105EEX Two component transcriptional regulator (Winged helix family HF553_RS16505 ENOG4105CXN decarboxylase HF553_RS16510 ENOG4105D5Q Arginine ornithine antiporter HF553_RS16520 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HF553_RS16525 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HF553_RS16530 ENOG4105EV9 Alpha Beta Hydrolase HF553_RS16535 ENOG4105NNH LexA regulated protein HF553_RS16540 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HF553_RS16545 ENOG41090R7 Ferric uptake HF553_RS16550 ENOG4106P55 Transcriptional regulator HF553_RS16555 ENOG4107EFR Flavocytochrome c HF553_RS16560 ENOG41079YP Citrate utilization protein b HF553_RS16565 ENOG4105CSH Transporter HF553_RS16570 ENOG4105GX6 (LipO)protein HF553_RS16575 ENOG4105J5J Outer membrane porin HF553_RS16585 ENOG4105CI1 PTS System HF553_RS16595 ENOG4105CE4 GlcNAc 6-P deacetylase HF553_RS16600 ENOG4105E2R ROK family HF553_RS16605 ENOG4105D4U had-superfamily hydrolase, subfamily iia HF553_RS16610 ENOG4105CAQ asparagine synthetase HF553_RS16645 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HF553_RS16655 ENOG4105C9A Phoh family HF553_RS16665 ENOG4108JU5 Magnesium and cobalt efflux protein HF553_RS16670 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HF553_RS16675 ENOG4107RP9 extracellular solute-binding protein, family 3 HF553_RS16680 ENOG4105EAD ABC transporter HF553_RS16685 ENOG4105DRP amino acid AbC transporter HF553_RS16690 ENOG4105CDA abc transporter atp-binding protein HF553_RS16705 ENOG4107PAI alpha helical protein HF553_RS16710 ENOG4108JUB Transcriptional regulator HF553_RS16715 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) HF553_RS16740 ENOG4105DJF DNA polymerase III, delta' subunit HF553_RS16745 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) HF553_RS16750 ENOG4107QZB decarboxylase HF553_RS16755 ENOG4108TGR phosphatase HF553_RS16760 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HF553_RS16765 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) HF553_RS16770 ENOG4105CJN penicillin-binding protein HF553_RS16775 ENOG4105CNI cell division protein FtsW HF553_RS16780 ENOG4105K6T rare lipoprotein A HF553_RS16785 ENOG4105DZ1 carboxypeptidase HF553_RS16790 ENOG4108Z43 UPF0250 protein HF553_RS16800 ENOG41064T2 transcriptional regulator, lysR family HF553_RS16820 ENOG4107Z6W Protein CrcB homolog HF553_RS16835 ENOG4105CEE C4-dicarboxylate transporter HF553_RS16840 ENOG4106YYS transcriptional regulatory protein HF553_RS16845 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HF553_RS16850 ENOG4105DUA (citrate (pro-3S)-lyase ligase HF553_RS16855 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) HF553_RS16860 ENOG4105CI0 Citrate lyase HF553_RS16865 ENOG4105CHY citrate lyase, alpha HF553_RS16870 ENOG4105YGP holo-ACP synthase CitX HF553_RS16880 ENOG4107QPK )-transporter HF553_RS16885 ENOG4105KTS ribonuclease HF553_RS16890 ENOG4105NXH GreA GreB family elongation factor HF553_RS16895 ENOG4105E2A Dehydrogenase HF553_RS16900 ENOG4108U51 Universal stress protein HF553_RS16910 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HF553_RS16915 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) HF553_RS16925 ENOG4108JU3 Alkyl hydroperoxide reductase HF553_RS16930 ENOG4105D3R alkyl hydroperoxide reductase HF553_RS16935 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HF553_RS16940 ENOG4105DQS Transcriptional regulator HF553_RS16945 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HF553_RS16950 ENOG4105GTN ParB Domain Protein Nuclease HF553_RS16955 ENOG4105CHM Aminotransferase HF553_RS16960 ENOG4107SCQ Iron-containing alcohol dehydrogenase HF553_RS16965 ENOG4105VCD cytoplasmic protein HF553_RS16970 ENOG4105D22 carbon starvation protein HF553_RS16980 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HF553_RS16985 ENOG4105WQI isochorismatase HF553_RS16990 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HF553_RS16995 ENOG4105E4F Isochorismate synthase HF553_RS17000 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HF553_RS17005 ENOG4105E8G Major facilitator Superfamily HF553_RS17010 ENOG4105DQ5 transport system permease protein HF553_RS17015 ENOG4105TVJ transport system, permease HF553_RS17020 ENOG4105E0A ABC, transporter HF553_RS17025 ENOG4108QY5 Ferric enterobactin transport protein HF553_RS17030 ENOG4105C0W non-ribosomal peptide synthetase HF553_RS17035 ENOG41085A6 mbth domain-containing protein HF553_RS17040 ENOG4105E93 esterase HF553_RS17045 ENOG4107RNH Outer membrane receptor FepA HF553_RS17050 ENOG4108TSE Transferase HF553_RS17060 ENOG4105WQ6 Membrane HF553_RS17065 ENOG4105HFT AraC family transcriptional regulator HF553_RS17070 ENOG41067SE Tetr family transcriptional regulator HF553_RS17075 ENOG4105MSB protein, conserved in bacteria HF553_RS17080 ENOG4108RCM Nitroreductase HF553_RS17090 ENOG4105CUY Mechanosensitive ion channel HF553_RS17095 ENOG4105C85 amino acid HF553_RS17105 ENOG4108KBJ Inner membrane protein YkgB HF553_RS17110 ENOG41066GK UPF0379 protein ykgI HF553_RS17115 ENOG4107QN2 dihydrolipoyl dehydrogenase HF553_RS17120 ENOG4108K01 transcriptional regulator HF553_RS17140 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) HF553_RS17145 ENOG4105CKK Glycosyl transferase, family 2 HF553_RS17170 ENOG4106KCD HTH_LUXR HF553_RS17180 ENOG4106721 fimbriae Y protein HF553_RS17185 ENOG4108Q9V regulatoR HF553_RS17190 ENOG4108ZI2 Fimbrial protein HF553_RS17195 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) HF553_RS17200 ENOG4105CW0 outer membrane usher protein HF553_RS17205 ENOG4108AF8 Chaperone HF553_RS17215 ENOG4108WDE Fimbrial protein HF553_RS17225 ENOG4105WQ3 Rna-binding protein HF553_RS17230 ENOG4105S2T inner membrane protein YbcI HF553_RS17250 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HF553_RS17260 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HF553_RS17265 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HF553_RS17270 ENOG4105C5B carbamate kinase HF553_RS17275 ENOG4105G5A Protein of unknown function (DUF2877) HF553_RS17280 ENOG4107REC cytoplasmic protein HF553_RS17285 ENOG4107R1Q Membrane protein FdrA HF553_RS17290 ENOG4105DG4 malate L-lactate dehydrogenase HF553_RS17295 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HF553_RS17300 ENOG4105S0E allantoin catabolism protein HF553_RS17305 ENOG4105BZW Glycerate kinase HF553_RS17310 ENOG4105DTE Xanthine uracil vitamin C permease HF553_RS17320 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HF553_RS17330 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HF553_RS17335 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HF553_RS17340 ENOG41060W2 glyoxylate carboligase HF553_RS17365 ENOG4108UMI ABC transporter, permease HF553_RS17370 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HF553_RS17375 ENOG4105D01 (LipO)protein HF553_RS17385 ENOG4105CV6 ABC transporter, permease HF553_RS17390 ENOG4108I0Y (ABC) transporter HF553_RS17395 ENOG4108UJV acyl-CoA thioesterase i HF553_RS17400 ENOG4105E1F short-chain dehydrogenase reductase HF553_RS17405 ENOG4107QR8 Thioredoxin HF553_RS17410 ENOG4105C4B ABC transporter, permease HF553_RS17415 ENOG41083J0 (ABC) transporter HF553_RS17420 ENOG4107QX8 SPFH domain, Band 7 family protein HF553_RS17425 ENOG4105G5H Membrane HF553_RS17430 ENOG4108Z6Z Transcriptional regulator HF553_RS17435 ENOG4105C59 p-type ATPase HF553_RS17445 ENOG4105MBR gumn family HF553_RS17450 ENOG4108Z66 YbaK ebsC protein HF553_RS17455 ENOG4105CGH 5'-nucleotidase HF553_RS17460 ENOG4105EU0 Major facilitator Superfamily HF553_RS17465 ENOG4105CKD glutathione-regulated potassium-efflux system protein HF553_RS17470 ENOG4107RE1 Inosine-guanosine kinase HF553_RS17505 ENOG4107QMP dna polymerase iii subunits gamma and tau HF553_RS17515 ENOG4105WD1 Membrane HF553_RS17520 ENOG4108URS primosomal replication protein n'' HF553_RS17525 ENOG4106428 Protein of unknown function (DUF2496) HF553_RS17530 ENOG4105DNE Transposase HF553_RS17535 ENOG4105EGS Mechanosensitive ion channel HF553_RS17540 ENOG4107XI7 Tetr family transcriptional regulator HF553_RS17545 ENOG4105C1P efflux transporter, rnd family, mfp subunit HF553_RS17550 ENOG4105BZS acriflavin resistance protein HF553_RS17555 ENOG4108UKR Biofilm formation regulator YbaJ HF553_RS17565 ENOG4108UW5 maltose o-acetyltransferase HF553_RS17570 ENOG4105GSJ Inner membrane protein ylaC HF553_RS17585 ENOG41066DG (EAL) domain protein HF553_RS17595 ENOG41080UX Methyltransferase HF553_RS17600 ENOG4108MNP Glycoprotein polysaccharide metabolism HF553_RS17605 ENOG4105C29 acyl-CoA thioesterase HF553_RS17610 ENOG4105BZU Histidine kinase HF553_RS17615 ENOG4108YZA Nitrogen regulatory protein pii HF553_RS17620 ENOG4105BZ1 (ABC) transporter HF553_RS17625 ENOG4105BZ1 (ABC) transporter HF553_RS17630 ENOG4108XM1 transcriptional regulator AsnC family HF553_RS17645 ENOG4108NFA extracellular solute-binding protein HF553_RS17655 ENOG4108TGP Thioesterase superfamily protein HF553_RS17660 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HF553_RS17665 ENOG4105EIN peptidylprolyl cis-trans isomerase HF553_RS17670 ENOG4105K70 DNA-binding protein HF553_RS17675 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HF553_RS17695 ENOG4105M85 Bola protein HF553_RS17700 ENOG4105IEY (LipO)protein HF553_RS17705 ENOG4105EYM Major Facilitator superfamily HF553_RS17710 ENOG4105E2S oxidase) subunit II HF553_RS17715 ENOG4105BZ9 Cytochrome C oxidase, subunit I HF553_RS17720 ENOG4105CCU oxidase (Subunit III) HF553_RS17725 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HF553_RS17750 ENOG4107RDB Major Facilitator HF553_RS17760 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HF553_RS17765 ENOG4107S0N DJ-1 family HF553_RS17780 ENOG4106S9K Transcriptional regulator HF553_RS17790 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HF553_RS17795 ENOG4108MP3 ABC transporter, permease HF553_RS17800 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component HF553_RS17810 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) HF553_RS17815 ENOG4105CTB Polyprenyl synthetase HF553_RS17825 ENOG4105CPC Aldo Keto reductase HF553_RS17830 ENOG4108ZAI phosphatidylglycerophosphatase a HF553_RS17835 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HF553_RS17840 ENOG4107YIM Involved in the transcription termination process (By similarity) HF553_RS17850 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HF553_RS17860 ENOG4108KIC (LipO)protein HF553_RS17865 ENOG4105DRB nucleoside-specific channel-forming protein HF553_RS17875 ENOG4105N1F Hnh endonuclease HF553_RS17890 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HF553_RS17900 ENOG4105VIE preprotein translocase, subunit YajC HF553_RS17920 ENOG4105D3R alkyl hydroperoxide reductase HF553_RS17930 ENOG4107R28 alpha amylase, catalytic region HF553_RS17935 ENOG4105C85 amino acid HF553_RS17940 ENOG4105CWM branched-chain amino acid transport system II carrier protein HF553_RS17945 ENOG4105BZU Histidine kinase HF553_RS17950 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HF553_RS17955 ENOG4107RH8 nuclease SbcCD subunit D HF553_RS17960 ENOG4105EYH Exonuclease HF553_RS17965 ENOG4105F27 Major Facilitator HF553_RS17970 ENOG4105DKQ ROK family HF553_RS17985 ENOG4105HBA AroM protein HF553_RS17990 ENOG4105SS3 HF553_RS18005 ENOG4105II7 pyrroline-5-carboxylate reductase HF553_RS18010 ENOG4105BZU Histidine kinase HF553_RS18015 ENOG4105VIF phosphate starvation-inducible protein HF553_RS18035 ENOG4105CPF Cell wall formation (By similarity) HF553_RS18040 ENOG4105UNH Membrane HF553_RS18045 ENOG4105FR5 inner membrane protein YaiY HF553_RS18050 ENOG4107QS8 (LipO)protein HF553_RS18055 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HF553_RS18060 ENOG4107R6D beta-lactam binding protein AmpH HF553_RS18065 ENOG4108PNB DNA-binding transcriptional regulator HF553_RS18070 ENOG4108NSE outer membrane autotransporter barrel HF553_RS18075 ENOG4105D52 delta-aminolevulinic acid dehydratase HF553_RS18080 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HF553_RS18085 ENOG4105DXD 2-methylcitrate dehydratase HF553_RS18090 ENOG4105BZN citrate synthase HF553_RS18095 ENOG4105CR4 methylisocitrate lyase HF553_RS18100 ENOG4108JU7 Transcriptional regulator HF553_RS18105 ENOG4105TDT uncharacterized protein yahO HF553_RS18110 ENOG4105E82 cytochrome subunit of dehydrogenase HF553_RS18130 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HF553_RS18135 ENOG4105C4M (Ubiquinol oxidase) subunit I HF553_RS18160 ENOG4107QMH DNA methylase HF553_RS18165 ENOG4105JHE Major Facilitator Superfamily HF553_RS18195 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HF553_RS18215 ENOG4108T1M outer membrane protein x HF553_RS18230 ENOG4107XTP (EAL) domain protein HF553_RS18245 ENOG4105X0I Fimbrial HF553_RS18250 ENOG4108VEV chaperone HF553_RS18255 ENOG4105CW0 outer membrane usher protein HF553_RS18300 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HF553_RS18310 ENOG4108YGG dna repair protein HF553_RS18315 ENOG4105MFG Antirestriction protein HF553_RS18320 ENOG4106H6R UPF0380 protein HF553_RS18325 ENOG4105F4K antigen 43 HF553_RS18440 ENOG4105C94 Transporter HF553_RS18450 ENOG4105F2I Transposase HF553_RS18465 ENOG4108P8R HF553_RS18470 ENOG4108P8R HF553_RS18505 ENOG4105FCK Membrane HF553_RS18520 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) HF553_RS18525 ENOG4105CIN aminoacyl-histidine dipeptidase HF553_RS18530 ENOG4108S2Y peptide Chain Release factor HF553_RS18545 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HF553_RS18550 ENOG4105E7A Glutamine amidotransferase HF553_RS18565 ENOG4107QPN acyl-Coa dehydrogenase HF553_RS18570 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HF553_RS18580 ENOG4105T40 surface antigen msp4 family protein HF553_RS18595 ENOG4108XM1 transcriptional regulator AsnC family HF553_RS18635 ENOG4105W7K Transcriptional regulator HF553_RS18720 ENOG4105CS6 Rhs element vgr protein HF553_RS18805 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HF553_RS18845 ENOG4107RZZ dna polymerase iii epsilon subunit HF553_RS18850 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) HF553_RS18855 ENOG4105D1A Methyltransferase HF553_RS18865 ENOG4105E9H Lytic Murein transglycosylase HF553_RS18870 ENOG4105F2W methyltransferase HF553_RS18880 ENOG4105F27 Major Facilitator HF553_RS18885 ENOG4105HEI LysR family (Transcriptional regulator HF553_RS18890 ENOG4105CV8 reductase HF553_RS18925 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HF553_RS18930 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HF553_RS18935 ENOG4108UMI ABC transporter, permease HF553_RS18940 ENOG4105D01 (LipO)protein HF553_RS18945 ENOG4108R8X outer membrane lipoprotein HF553_RS18950 ENOG4108R96 Methyltransferase, YaeB family HF553_RS18960 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HF553_RS18965 ENOG4108YZN class I peptide chain release factor HF553_RS18970 ENOG4108VWS Yaeq family HF553_RS18980 ENOG4105M1T rho-binding antiterminator HF553_RS18990 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HF553_RS18995 ENOG4105CXN decarboxylase HF553_RS19000 ENOG4108M1A Chitin-binding protein HF553_RS19010 ENOG4105C0B DNA polymerase III (alpha subunit) HF553_RS19030 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) HF553_RS19035 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HF553_RS19040 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HF553_RS19055 ENOG4105KNE Phosphatidate cytidylyltransferase HF553_RS19070 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) HF553_RS19075 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) HF553_RS19085 ENOG4105CE9 30S ribosomal protein S2 HF553_RS19090 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HF553_RS19105 ENOG4105CSH Transporter HF553_RS19115 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HF553_RS19120 ENOG4105C0H protease HF553_RS19135 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HF553_RS19140 ENOG4105EN6 Membrane HF553_RS19145 ENOG4108YX9 iron--sulfur cluster insertion protein erpA HF553_RS19160 ENOG4106RDH Protein of unknown function (DUF2544) HF553_RS19170 ENOG4105UGQ Fimbrial HF553_RS19175 ENOG4105NEV Fimbrial HF553_RS19180 ENOG4108FZ9 Chaperone HF553_RS19185 ENOG4106PG1 outer membrane usher protein HF553_RS19195 ENOG4105S6R Iron-hydroxamate transporter permease subunit HF553_RS19200 ENOG4105J76 Periplasmic binding protein HF553_RS19205 ENOG4105E0A ABC, transporter HF553_RS19210 ENOG4105E0K tonB-dependent siderophore receptor HF553_RS19215 ENOG4105BZ4 penicillin-binding protein HF553_RS19220 ENOG4105CQ7 ATP-dependent helicase HF553_RS19225 ENOG4107XID 2'-5' rna ligase HF553_RS19235 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters HF553_RS19240 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) HF553_RS19245 ENOG4105DJ0 Poly(A) Polymerase HF553_RS19250 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HF553_RS19275 ENOG4108VEV chaperone HF553_RS19280 ENOG4105CW0 outer membrane usher protein HF553_RS19285 ENOG4108XEY fimbrial-like adhesin protein HF553_RS19305 ENOG4107BJW polysaccharide deacetylase HF553_RS19310 ENOG4108YTN IIa component HF553_RS19315 ENOG4105E3A (ABC) transporter HF553_RS19320 ENOG4105DA5 (ABC) transporter HF553_RS19325 ENOG41077A9 carbonic anhydrase HF553_RS19330 ENOG4108UGV hypoxanthine phosphoribosyltransferase HF553_RS19335 ENOG4105DZG Dehydrogenase HF553_RS19340 ENOG4105E3B Multicopper oxidase HF553_RS19345 ENOG4108ZRK uncharacterized protein yacC HF553_RS19360 ENOG4105MVE transcriptional regulator HF553_RS19365 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HF553_RS19370 ENOG4107S2N Type III effector Hrp-dependent HF553_RS19375 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) HF553_RS19385 ENOG4107QIJ Aconitate hydratase 2 HF553_RS19390 ENOG4108NST exported protein HF553_RS19405 ENOG4107QN2 dihydrolipoyl dehydrogenase HF553_RS19410 ENOG4107QSN dihydrolipoamide acetyltransferase HF553_RS19415 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HF553_RS19430 ENOG4105CT4 transporter HF553_RS19435 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) HF553_RS19440 ENOG4106A72 regulatory protein AmpE HF553_RS19450 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HF553_RS19455 ENOG4108ZUW Major pilin subunit HF553_RS19460 ENOG4107QHF type ii secretion system protein e HF553_RS19465 ENOG4105D7Q type ii secretion system HF553_RS19475 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HF553_RS19485 ENOG41067SF Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) HF553_RS19500 ENOG4105M6F mutator MutT protein HF553_RS19520 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HF553_RS19525 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HF553_RS19530 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HF553_RS19550 ENOG4105CNI cell division protein FtsW HF553_RS19560 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) HF553_RS19565 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HF553_RS19575 ENOG4105CJN penicillin-binding protein HF553_RS19580 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HF553_RS19595 ENOG4107B7Y DNA-binding transcriptional regulator FruR HF553_RS19600 ENOG4108ZP8 Acetolactate synthase small subunit HF553_RS19605 ENOG4105C7K acetolactate synthase HF553_RS19610 ENOG41064T2 transcriptional regulator, lysR family HF553_RS19630 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) HF553_RS19670 ENOG4108KF1 Membrane HF553_RS19675 ENOG41063TF transcriptional regulator (AraC HF553_RS19690 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HF553_RS19710 ENOG4105CQ2 DNA polymerase HF553_RS19720 ENOG4105D3G Pseudouridine synthase HF553_RS19730 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HF553_RS19740 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HF553_RS19750 ENOG4105NWN ApaG protein HF553_RS19790 ENOG4105M5B (LipO)protein HF553_RS19795 ENOG4105C54 Major Facilitator superfamily HF553_RS19800 ENOG4105WQV ferredoxin-like protein HF553_RS19805 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HF553_RS19850 ENOG4108XNW Transcriptional activatory protein CaiF HF553_RS19855 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HF553_RS19860 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HF553_RS19885 ENOG4105CHY citrate lyase, alpha HF553_RS19890 ENOG4105CI0 Citrate lyase HF553_RS19900 ENOG4105DUA (citrate (pro-3S)-lyase ligase HF553_RS19915 ENOG4107QSA Oxaloacetate decarboxylase HF553_RS19920 ENOG4105D9Q decarboxylase (Beta subunit) HF553_RS19925 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HF553_RS19930 ENOG4106YYS transcriptional regulatory protein HF553_RS19950 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HF553_RS19965 ENOG4105DTN riboflavin biosynthesis protein ribF HF553_RS19970 ENOG410647N response to DNA damage stimulus HF553_RS19990 ENOG41063Z6 transcriptional regulator, lysR family HF553_RS20010 ENOG4105C4X radical SAM domain protein HF553_RS20015 ENOG41061MV Arylsulfatase HF553_RS20025 ENOG4105CGH 5'-nucleotidase HF553_RS20060 ENOG4106PH7 chaperone HF553_RS20075 ENOG4105MHR Fimbrial protein HF553_RS20080 ENOG4105CW0 outer membrane usher protein HF553_RS20085 ENOG4108AF8 Chaperone HF553_RS20090 ENOG4108RQP Major type 1 subunit fimbrin HF553_RS20140 ENOG4108WTA UPF0412 protein YaaI HF553_RS20145 ENOG4108QUJ UPF0174 protein YaaW HF553_RS20150 ENOG4106HK8 GPR1 FUN34 yaaH family protein HF553_RS20155 ENOG4108RIR Molybdenum cofactor biosynthesis protein HF553_RS20160 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HF553_RS20165 ENOG4105BZG amino acid carrier protein HF553_RS20175 ENOG4105D98 threonine synthase HF553_RS20185 ENOG4105CFH Aspartokinase HF553_RS20195 ENOG4106FVC RNA methyltransferase HF553_RS20200 ENOG410759A HF553_RS20205 ENOG41065U4 response regulator HF553_RS20215 ENOG4108PNB DNA-binding transcriptional regulator HF553_RS20225 ENOG4108VCD Chaperone HF553_RS20230 ENOG4105CW0 outer membrane usher protein HF553_RS20245 ENOG4105CT7 inner membrane cred family protein HF553_RS20250 ENOG4105EB3 Histidine kinase HF553_RS20255 ENOG4105E3W Two component transcriptional regulator (Winged helix family HF553_RS20260 ENOG4108RH0 Crea protein HF553_RS20265 ENOG4105UEI Transcriptional Regulator AraC Family HF553_RS20285 ENOG4107SC1 transglycosylase HF553_RS20290 ENOG4105C5H ABC transporter HF553_RS20295 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HF553_RS20300 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HF553_RS20305 ENOG4105EAC phosphoserine phosphatase HF553_RS20310 ENOG41062Z9 Membrane HF553_RS20345 ENOG4105G0K glycine radical enzyme YjjI family HF553_RS20350 ENOG41076CZ activating enzyme HF553_RS20355 ENOG4105EYA deoxyribonuclease HF553_RS20360 ENOG4108NRW Phospholipase, patatin family HF553_RS20370 ENOG4105K3G Periplasmic Protein HF553_RS20380 ENOG4105PAD Hydrolase HF553_RS20385 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HF553_RS20390 ENOG4108WPU DNA polymerase III subunit psi HF553_RS20415 ENOG4105YBH Protein of unknown function (DUF1435) HF553_RS20420 ENOG4105BZU Histidine kinase HF553_RS20425 ENOG4108819 ferric iron reductase HF553_RS20430 ENOG4108UIN ybak prolyl-trna synthetase associated region HF553_RS20435 ENOG4108T94 DNA-binding transcriptional activator BglJ HF553_RS20440 ENOG4108N8T regulatoR HF553_RS20445 ENOG4105DWK Membrane HF553_RS20460 ENOG4106CVF DNA replication protein HF553_RS20465 ENOG4105RI1 glycoprotein receptor HF553_RS20475 ENOG4105C8Q Methyl-accepting chemotaxis HF553_RS20480 ENOG4105D22 carbon starvation protein HF553_RS20485 ENOG4105VCD cytoplasmic protein HF553_RS20490 ENOG4105CKI cobalamin synthesis protein HF553_RS20495 ENOG41063TF transcriptional regulator (AraC HF553_RS20500 ENOG4105E82 cytochrome subunit of dehydrogenase HF553_RS20505 ENOG4108HFV HF553_RS20520 ENOG4105C26 Dehydrogenase HF553_RS20525 ENOG4105DNE Transposase HF553_RS20530 ENOG41083G8 Multidrug resistance protein MdtM HF553_RS20535 ENOG4106BRA Membrane HF553_RS20540 ENOG4105CBP Major Facilitator HF553_RS20545 ENOG41074DU domain protein HF553_RS20550 ENOG4108P2H Inner membrane protein YjiG HF553_RS20555 ENOG4105DYB Isoaspartyl dipeptidase HF553_RS20560 ENOG4107YNJ LysR family Transcriptional regulator HF553_RS20580 ENOG4105C6F GntR Family Transcriptional Regulator HF553_RS20600 ENOG4105KZM cytoplasmic protein HF553_RS20610 ENOG4105DTA methyltransferase HF553_RS20660 ENOG4107QVY Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HF553_RS20680 ENOG4105C0D helicase HF553_RS20695 ENOG4107QMH DNA methylase HF553_RS20715 ENOG4105DQ4 alcohol dehydrogenase HF553_RS20720 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HF553_RS20725 ENOG4105CPQ Dehydrogenase HF553_RS20730 ENOG4105CHR reductase HF553_RS20735 ENOG4105C6Z Gluconate HF553_RS20740 ENOG4105K2J Transcriptional regulator HF553_RS20745 ENOG4108K5H permease YjgP YjgQ family protein HF553_RS20750 ENOG4108M8S permease YjgP YjgQ family protein HF553_RS20760 ENOG4105MYG DNA polymerase iii, chi subunit HF553_RS20765 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HF553_RS20770 ENOG4108M3P Membrane HF553_RS20775 ENOG4108MJ3 acetyltransferase HF553_RS20785 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase HF553_RS20790 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HF553_RS20795 ENOG4105DBV ornithine carbamoyltransferase HF553_RS20800 ENOG4105XEP YhcH YjgK YiaL family protein HF553_RS20805 ENOG4105CEU Arginine dihydrolase HF553_RS20810 ENOG4105C5B carbamate kinase HF553_RS20815 ENOG4105DBV ornithine carbamoyltransferase HF553_RS20820 ENOG4105CSX c4-dicarboxylate anaerobic carrier HF553_RS20825 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) HF553_RS20835 ENOG41077AM PyrBI operon attenuator HF553_RS20850 ENOG4105KME endoribonuclease L-psp HF553_RS20865 ENOG4105D4X repressor HF553_RS20870 ENOG4105C5Y PTS System HF553_RS20875 ENOG4105CG3 alpha amylase, catalytic region HF553_RS20880 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HF553_RS20885 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HF553_RS20890 ENOG4105K4U addiction module toxin, RelE StbE family HF553_RS20900 ENOG4105EMD TRANSCRIPTIONal HF553_RS20915 ENOG41069H0 dihydroorotase EC 3.5.2.3 HF553_RS20945 ENOG4108XVM Cytochrome b(562) HF553_RS20950 ENOG4105CMS peptidase U62, modulator of DNA gyrase HF553_RS20960 ENOG4105F0H myo-inositol catabolism protein HF553_RS20970 ENOG4105IE8 Alpha-ketoglutarate permease HF553_RS20975 ENOG4105CK5 oxidoreductase HF553_RS20980 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) HF553_RS20985 ENOG4105D7K pfkb domain protein HF553_RS20995 ENOG4107VG4 Xylose isomerase domain protein TIM barrel HF553_RS21000 ENOG4108MYR Secreted protein HF553_RS21025 ENOG4105C26 Dehydrogenase HF553_RS21030 ENOG4105DH8 myo-inositol catabolism HF553_RS21035 ENOG4107QNK )-transporter HF553_RS21040 ENOG4107QNK )-transporter HF553_RS21045 ENOG4105CHC glucokinase (EC 2.7.1.2) HF553_RS21050 ENOG4105DFU Cell wall formation (By similarity) HF553_RS21060 ENOG4105F0N pyrophosphate phospho-hydrolase HF553_RS21065 ENOG41069H0 dihydroorotase EC 3.5.2.3 HF553_RS21070 ENOG4105DJB Major Facilitator Superfamily HF553_RS21075 ENOG4108ZHD aig2 family HF553_RS21095 ENOG4105C37 (CBS) domain HF553_RS21100 ENOG41061GZ Protein of unknown function (DUF1107) HF553_RS21105 ENOG4108UUE Transcriptional regulator HF553_RS21110 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HF553_RS21115 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HF553_RS21120 ENOG4105KVH Transcriptional regulator HF553_RS21125 ENOG4105ECR NmrA family HF553_RS21130 ENOG4105DXC membrane HF553_RS21145 ENOG4108V1T peptidylprolyl cis-trans isomerase HF553_RS21150 ENOG4105FHY Opacity-associated protein A HF553_RS21160 ENOG4105K9Q Binds to the 23S rRNA (By similarity) HF553_RS21165 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HF553_RS21170 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) HF553_RS21175 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) HF553_RS21185 ENOG4105KIT UPF0379 protein yjfY HF553_RS21215 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HF553_RS21230 ENOG4108MXZ Esterase HF553_RS21235 ENOG4105WSB biofilm stress and motility protein A HF553_RS21240 ENOG4105S17 UPF0379 protein yjfN HF553_RS21245 ENOG4105CSU acyl-Coa dehydrogenase HF553_RS21250 ENOG4106032 Glutathionylspermidine synthase HF553_RS21255 ENOG4108KXT Conserved Protein HF553_RS21260 ENOG4105Z6B inner membrane protein yjfl HF553_RS21265 ENOG4107VNS Protein of unknown function (DUF2491) HF553_RS21270 ENOG4108P9J Phage shock protein A HF553_RS21275 ENOG4105FUX Conserved Protein HF553_RS21280 ENOG4105C2N RNA methyltransferase TrmH family group 3 HF553_RS21285 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HF553_RS21305 ENOG4105EPW hflc protein HF553_RS21310 ENOG4107QJR hflk protein HF553_RS21315 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HF553_RS21320 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) HF553_RS21335 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HF553_RS21340 ENOG4105K8N protein family UPF0079, ATPase HF553_RS21345 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HF553_RS21350 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HF553_RS21370 ENOG4106TNF Periplasmic binding protein HF553_RS21375 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) HF553_RS21390 ENOG4105EGS Mechanosensitive ion channel HF553_RS21395 ENOG4106CG8 Inner membrane protein YjeO HF553_RS21400 ENOG4107SC7 Inner membrane transporter yjeM HF553_RS21410 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HF553_RS21415 ENOG4105E33 succinate dehydrogenase HF553_RS21425 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) HF553_RS21435 ENOG4105KPY Small multidrug resistance protein HF553_RS21445 ENOG4106BSU Entericidin B HF553_RS21455 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) HF553_RS21460 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HF553_RS21465 ENOG4105MTB Uncharacterized protein YjeJ HF553_RS21470 ENOG4108ZVF (LipO)protein HF553_RS21485 ENOG4105DVH amino acid HF553_RS21490 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HF553_RS21495 ENOG4108IJ0 Aspartate ammonia-lyase HF553_RS21500 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HF553_RS21515 ENOG4108SIC Transcriptional regulator HF553_RS21535 ENOG4108I6E Sulfatase HF553_RS21540 ENOG4105T40 surface antigen msp4 family protein HF553_RS21650 ENOG4105TS0 gtp-binding protein HF553_RS21655 ENOG4108KZE transcriptional regulator HF553_RS21670 ENOG4106H6R UPF0380 protein HF553_RS21680 ENOG4106549 Antirestriction protein HF553_RS21685 ENOG4108YGG dna repair protein HF553_RS21700 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HF553_RS21735 ENOG4105SBG acid phosphatase HF553_RS21765 ENOG41068CG regulatoR HF553_RS21780 ENOG4108ZK4 sdia-regulated domain-containing protein HF553_RS21790 ENOG4108NEM leader-binding protein dmsD HF553_RS21795 ENOG4107KGK dmso reductase anchor subunit HF553_RS21800 ENOG4105QAX Iron-sulfur HF553_RS21805 ENOG4107QY8 reductase HF553_RS21810 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HF553_RS21815 ENOG4108MRH transcriptional regulatory protein HF553_RS21825 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HF553_RS21830 ENOG4107GFK fumarate HF553_RS21835 ENOG4105CT4 transporter HF553_RS21840 ENOG4105F8D glycoside hydrolase family 4 HF553_RS21845 ENOG4108K2B transcriptional regulator HF553_RS21850 ENOG4105CXN decarboxylase HF553_RS21855 ENOG4106ZGR Transcriptional regulator HF553_RS21860 ENOG4105D5Q Arginine ornithine antiporter HF553_RS21865 ENOG4105DIJ Phosphoethanolamine transferase HF553_RS21870 ENOG4105XJC Two component transcriptional regulator (Winged helix family HF553_RS21875 ENOG4105ECM Sensor protein basS pmrB HF553_RS21885 ENOG4105CSH Transporter HF553_RS21890 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HF553_RS21895 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HF553_RS21900 ENOG410870W N-acetyltransferase HF553_RS21915 ENOG41082ND Uncharacterized protein yjcO HF553_RS21925 ENOG4105CK2 sodium dicarboxylate symporter HF553_RS21930 ENOG4108W0S formate-dependent nitrite reductase complex HF553_RS21940 ENOG4108QKW cytochrome c-type biogenesis protein HF553_RS21945 ENOG4105DVI reductase, NrfD HF553_RS21950 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HF553_RS21955 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HF553_RS21965 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HF553_RS21970 ENOG41062QD Membrane HF553_RS21980 ENOG41067MG lrgb family HF553_RS21990 ENOG4105CMU LysR family (Transcriptional regulator HF553_RS21995 ENOG4105EEQ Na H antiporter HF553_RS22000 ENOG4105C7N Xanthine uracil vitamin C permease HF553_RS22010 ENOG4108Z4X TRANSCRIPTIONal HF553_RS22015 ENOG4108W3Q Transcriptional regulator HF553_RS22020 ENOG4108M8H domain protein HF553_RS22025 ENOG4105PMV Membrane HF553_RS22060 ENOG4108UUM single-stranded DNA-binding protein HF553_RS22065 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HF553_RS22080 ENOG4105MSB protein, conserved in bacteria HF553_RS22085 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HF553_RS22090 ENOG4105F0S class B acid phosphatase HF553_RS22095 ENOG4105CGF Aromatic amino acid aminotransferase HF553_RS22100 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HF553_RS22105 ENOG4105CDU Replicative dna helicase HF553_RS22110 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HF553_RS22115 ENOG4105P4Z Phage shock protein G HF553_RS22120 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HF553_RS22130 ENOG4105MYN Zinc uptake regulation protein HF553_RS22135 ENOG4105VDW Csbd family HF553_RS22145 ENOG4107R73 Mate efflux family protein HF553_RS22150 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) HF553_RS22155 ENOG41080IJ Diacylglycerol kinase HF553_RS22175 ENOG4107W52 maltose operon periplasmic protein HF553_RS22185 ENOG4108IJ9 (ABC) transporter HF553_RS22190 ENOG4107FKK extracellular solute-binding protein family 1 HF553_RS22195 ENOG4105D56 permease protein HF553_RS22200 ENOG4105EG2 ABC transporter, permease HF553_RS22210 ENOG4105E3R (LipO)protein HF553_RS22215 ENOG4108Q9C Periplasmic Protein HF553_RS22220 ENOG4108MDC (LipO)protein HF553_RS22235 ENOG4105CFH Aspartokinase HF553_RS22250 ENOG410667J hydrolase HF553_RS22255 ENOG4105E98 transcriptional regulator DeoR family HF553_RS22260 ENOG4108ZR5 Conserved Protein HF553_RS22265 ENOG4105FE9 pseudouridine synthase HF553_RS22270 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HF553_RS22285 ENOG4105EAM Na Pi-cotransporter HF553_RS22290 ENOG4105C3R Methionine synthase HF553_RS22295 ENOG41069M3 Transcriptional regulator HF553_RS22310 ENOG4108I9X Isocitrate lyase HF553_RS22315 ENOG4107QP3 malate synthase g HF553_RS22325 ENOG4105K5X acetyltransferase HF553_RS22350 ENOG4105DC1 bifunctional purine biosynthesis protein purh HF553_RS22355 ENOG4105C12 Phosphoribosylglycinamide synthetase HF553_RS22360 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HF553_RS22365 ENOG4105BZU Histidine kinase HF553_RS22375 ENOG4108T8B Protein of unknown function (DUF1481) HF553_RS22380 ENOG4105K70 DNA-binding protein HF553_RS22385 ENOG4105R2J Conserved Protein HF553_RS22420 ENOG4105D06 uba thif-type nad fad binding protein HF553_RS22425 ENOG4105WHD thiamine biosynthesis protein ThiS HF553_RS22435 ENOG4105D41 biosynthesis protein thiH HF553_RS22455 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) HF553_RS22460 ENOG4107QIH DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) HF553_RS22465 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) HF553_RS22470 ENOG4108VZM 50s ribosomal protein L10 HF553_RS22485 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HF553_RS22490 ENOG4105PM1 preprotein translocase subunit SecE HF553_RS22495 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) HF553_RS22530 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HF553_RS22535 ENOG4105D4A Cell wall formation (By similarity) HF553_RS22580 ENOG4108Y73 Membrane HF553_RS22595 ENOG4105C5Q Transcriptional regulator HF553_RS22630 ENOG4105DIJ Phosphoethanolamine transferase HF553_RS22635 ENOG4106R3P AraC family transcriptional regulator HF553_RS22645 ENOG4105DCT glycerol dehydrogenase HF553_RS22650 ENOG4108XC3 NADH ubiquinone oxidoreductase HF553_RS22660 ENOG4105SYT Methylenetetrahydrofolate reductase HF553_RS22670 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HF553_RS22675 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) HF553_RS22680 ENOG4105CGH 5'-nucleotidase HF553_RS22695 ENOG4105D64 Mechanosensitive ion channel HF553_RS22700 ENOG4105CFH Aspartokinase HF553_RS22705 ENOG4105C28 cystathionine HF553_RS22715 ENOG4108MR7 Arylsulfotransferase HF553_RS22730 ENOG4105C25 Primosomal protein n' HF553_RS22735 ENOG4105ETE Transcriptional regulator (LacI family HF553_RS22740 ENOG41063M6 Cell Division Protein HF553_RS22755 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HF553_RS22770 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HF553_RS22780 ENOG4105CBT Fructose-1,6-bisphosphatase HF553_RS22785 ENOG4105DP0 ferredoxin-NADP reductase HF553_RS22790 ENOG4108VTS Membrane HF553_RS22795 ENOG4105EBK exported protein HF553_RS22820 ENOG4105D7K pfkb domain protein HF553_RS22825 ENOG4105CT4 transporter HF553_RS22835 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HF553_RS22840 ENOG4105CTQ phosphohexokinase HF553_RS22850 ENOG4105FMW periplasmic HF553_RS22855 ENOG4105E3W Two component transcriptional regulator (Winged helix family HF553_RS22860 ENOG4105E0F Histidine kinase HF553_RS22870 ENOG4108RPX mosc domain containing protein HF553_RS22875 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HF553_RS22880 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HF553_RS22885 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HF553_RS22890 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HF553_RS22895 ENOG4108QGT oligogalacturonate-specific porin HF553_RS22920 ENOG4105DKG l-rhamnose isomerase HF553_RS22930 ENOG4105C0A alcohol dehydrogenase HF553_RS22945 ENOG4108UMN azlc family HF553_RS22955 ENOG4108V87 frv operon regulatory protein HF553_RS22960 ENOG4108V87 frv operon regulatory protein HF553_RS22975 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HF553_RS22980 ENOG4108MG3 formate dehydrogenase HF553_RS22995 ENOG41068KX affects formate dehydrogenase-N HF553_RS23005 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) HF553_RS23010 ENOG4108Z3N Transcriptional regulator HF553_RS23015 ENOG4105SUU thioesterase domain HF553_RS23030 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HF553_RS23035 ENOG4105E98 transcriptional regulator DeoR family HF553_RS23040 ENOG4108MGF sugar kinase HF553_RS23045 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HF553_RS23050 ENOG4105D2M Aldolase HF553_RS23055 ENOG4107QKS N-acylglucosamine 2-epimerase HF553_RS23060 ENOG4107WI4 Aldose-1-epimerase HF553_RS23065 ENOG4105CJQ hydrolase, family 31 HF553_RS23070 ENOG4105CT4 transporter HF553_RS23075 ENOG4105CT4 transporter HF553_RS23080 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is HF553_RS23110 ENOG4108K4B hydrolase HF553_RS23115 ENOG4105CI3 gtp-binding protein typa HF553_RS23120 ENOG4105C5F glutamine synthetase HF553_RS23125 ENOG4105CUX Signal transduction histidine kinase HF553_RS23130 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HF553_RS23135 ENOG4106FIY HF553_RS23140 ENOG4105D4P Coproporphyrinogen iii oxidase HF553_RS23160 ENOG4105C2M dna polymerase I HF553_RS23165 ENOG4106HNH Acyl-transferase HF553_RS23170 ENOG4108Z33 Thiol disulfide Interchange Protein HF553_RS23180 ENOG4105PC1 Conserved Protein HF553_RS23185 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HF553_RS23190 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HF553_RS23225 ENOG4108RR8 protoporphyrinogen oxidase HF553_RS23230 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HF553_RS23235 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HF553_RS23250 ENOG4105CHU acetyl-coa acetyltransferase HF553_RS23255 ENOG4108MR7 Arylsulfotransferase HF553_RS23260 ENOG4107QK7 reductase HF553_RS23265 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HF553_RS23270 ENOG4105MDZ Transcriptional activator rfaH HF553_RS23275 ENOG4105F8V Hydrolase, tatD family HF553_RS23280 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HF553_RS23285 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HF553_RS23290 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HF553_RS23300 ENOG4105JC1 sterol-binding domain protein HF553_RS23310 ENOG4105CGY Dna recombination protein HF553_RS23315 ENOG4107SXA Phosphorylase HF553_RS23320 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HF553_RS23325 ENOG4105C4X radical SAM domain protein HF553_RS23335 ENOG4105DZ2 Transcriptional regulator HF553_RS23340 ENOG4105EMK carboxylate amino acid amine transporter HF553_RS23345 ENOG4105DQF Hydrolase HF553_RS23350 ENOG4108EUD Lysophospholipase HF553_RS23355 ENOG410829K Lysine exporter protein (Lyse ygga) HF553_RS23360 ENOG4105CCF Lysine exporter protein (Lyse ygga) HF553_RS23365 ENOG4105C9U ATP-dependent DNA helicase RecQ HF553_RS23370 ENOG4105HDD phospholipase HF553_RS23375 ENOG4108VUY thioesterase Superfamily protein HF553_RS23380 ENOG4105FR1 rard protein HF553_RS23395 ENOG4107QUT magnesium and cobalt transport protein CorA HF553_RS23400 ENOG4105C4R Atp-dependent dna helicase HF553_RS23405 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HF553_RS23410 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HF553_RS23415 ENOG4105CT0 Protein of unknown function, DUF484 HF553_RS23425 ENOG4105S7Z (LipO)protein HF553_RS23450 ENOG4107T0K Adenylate cyclase HF553_RS23460 ENOG41076E6 Uroporphyrinogen-III Synthase HF553_RS23465 ENOG4105ECF c-methyltransferase HF553_RS23470 ENOG410601J HemY protein HF553_RS23475 ENOG4108RS6 transposase HF553_RS23500 ENOG4105C85 amino acid HF553_RS23520 ENOG4105EGZ biosynthesis protein HF553_RS23525 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HF553_RS23530 ENOG4108WJ1 acetyltransferase HF553_RS23535 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HF553_RS23535 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HF553_RS23540 ENOG4105C1B dTDP-glucose 4-6-dehydratase HF553_RS23545 ENOG4108IJ1 Dehydrogenase HF553_RS23550 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HF553_RS23555 ENOG4105SFE lipopolysaccharide biosynthesis protein HF553_RS23560 ENOG4105ESV Glycosyl transferase, family 4 HF553_RS23565 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HF553_RS23590 ENOG4105C4R Atp-dependent dna helicase HF553_RS23600 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HF553_RS23610 ENOG4105EMY transcriptional regulator HF553_RS23630 ENOG4105C7B Threonine dehydratase HF553_RS23640 ENOG4105CM2 brancheD-chain amino acid aminotransferase HF553_RS23645 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HF553_RS23660 ENOG4105C0P Mg chelatase subunit ChlI HF553_RS23705 ENOG4107EJG GntR family transcriptional regulator HF553_RS23710 ENOG4105C0R drug resistance transporter emrb qaca subfamily HF553_RS23715 ENOG4105ETE Transcriptional regulator (LacI family HF553_RS23720 ENOG4108RVA ribokinase HF553_RS23725 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HF553_RS23730 ENOG4105CNN ABC, transporter HF553_RS23765 ENOG4108VVK transcriptional Regulator, AsnC HF553_RS23770 ENOG4105QTB Flavodoxin HF553_RS23785 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HF553_RS23800 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) HF553_RS23820 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) HF553_RS23825 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) HF553_RS23920 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) HF553_RS23925 ENOG4105F9E Shikimate 5-dehydrogenase HF553_RS23930 ENOG4105DM4 PTS System HF553_RS23935 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HF553_RS23940 ENOG4105C8U phosphate abc transporter HF553_RS23945 ENOG4105E2Z phosphate ABC transporter (Permease HF553_RS23950 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HF553_RS23960 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HF553_RS23965 ENOG4105C7N Xanthine uracil vitamin C permease HF553_RS23970 ENOG4108YYH Nadph-dependent fmn reductase HF553_RS23975 ENOG4105E8Q phosphopantetheinyl transferase HF553_RS24010 ENOG4105VG0 50S ribosomal protein l34