locus-tag	class	description
HF553_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
HF553_RS00035	COG2271	Major facilitator Superfamily
HF553_RS00040	COG0561	phosphatase activity
HF553_RS00045	COG2186	Transcriptional regulator
HF553_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
HF553_RS00055	COG0800	Aldolase
HF553_RS00065	COG2271	Major facilitator Superfamily
HF553_RS00070	COG2205	protein histidine kinase activity
HF553_RS00070	COG2198	Histidine kinase
HF553_RS00070	COG0784	Response regulator, receiver
HF553_RS00075	COG1879	ABC-type sugar transport system periplasmic component
HF553_RS00080	COG0745	RESPONSE REGULATOR receiver
HF553_RS00085	COG3005	denitrification pathway
HF553_RS00100	COG1858	cytochrome C peroxidase
HF553_RS00110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HF553_RS00115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HF553_RS00120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HF553_RS00130	COG1138	Cytochrome C-type biogenesis protein
HF553_RS00140	COG3088	subunit of a heme lyase
HF553_RS00140	COG4235	cytochrome complex assembly
HF553_RS00145	COG0823	Involved in the tonB-independent uptake of proteins
HF553_RS00150	COG5645	(Lipo)protein
HF553_RS00170	COG2149	membrane
HF553_RS00180	COG0641	radical SAM
HF553_RS00190	COG2610	gluconate transmembrane transporter activity
HF553_RS00195	COG0583	DNA-binding transcription factor activity
HF553_RS00205	COG2814	Major facilitator Superfamily
HF553_RS00230	COG0028	Belongs to the TPP enzyme family
HF553_RS00235	COG0440	acetolactate synthase activity
HF553_RS00240	COG1349	DNA-binding transcription factor activity
HF553_RS00250	COG0738	Major facilitator superfamily
HF553_RS00285	COG2188	Transcriptional regulator
HF553_RS00290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS00290	COG3711	transcriptional antiterminator
HF553_RS00295	COG3414	Phosphotransferase system galactitol-specific IIB component
HF553_RS00300	COG3775	system Galactitol-specific IIC component
HF553_RS00335	COG2723	6-phospho-beta-galactosidase activity
HF553_RS00355	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS00355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HF553_RS00360	COG3715	PTS system
HF553_RS00365	COG3716	PTS system mannose fructose sorbose family IID component
HF553_RS00380	COG5464	transposase or invertase
HF553_RS00410	COG1335	isochorismatase
HF553_RS00420	COG3710	Transcriptional regulator
HF553_RS00435	COG2771	luxR family
HF553_RS00455	COG0419	ATPase involved in DNA repair
HF553_RS00500	COG2003	Belongs to the UPF0758 family
HF553_RS00525	COG2020	methyltransferase activity
HF553_RS00530	COG3468	outer membrane autotransporter barrel domain protein
HF553_RS00590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HF553_RS00605	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HF553_RS00625	COG0582	viral genome integration into host DNA
HF553_RS00635	COG2211	Major facilitator Superfamily
HF553_RS00640	COG1501	Belongs to the glycosyl hydrolase 31 family
HF553_RS00645	COG2982	Protein involved in outer membrane biogenesis
HF553_RS00650	COG2233	PERMEase
HF553_RS00655	COG0786	glutamate:sodium symporter activity
HF553_RS00660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HF553_RS00665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HF553_RS00670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HF553_RS00690	COG2860	membrane
HF553_RS00700	COG0583	DNA-binding transcription factor activity
HF553_RS00705	COG1561	YicC-like family, N-terminal region
HF553_RS00730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HF553_RS00760	COG1519	Transferase
HF553_RS00765	COG0859	PFAM glycosyl transferase family 9
HF553_RS00770	COG0438	transferase activity, transferring glycosyl groups
HF553_RS00845	COG1216	Glycosyl transferase, family 2
HF553_RS00850	COG2861	carbohydrate metabolic process
HF553_RS00855	COG4942	peptidase
HF553_RS00865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HF553_RS00870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HF553_RS00890	COG2271	Major facilitator Superfamily
HF553_RS00900	COG1609	Transcriptional regulator
HF553_RS00905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HF553_RS00915	COG2186	Transcriptional regulator
HF553_RS00945	COG3722	fumarate hydratase activity
HF553_RS00950	COG0246	Mannitol dehydrogenase
HF553_RS00955	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS00955	COG2213	PTS system mannitol-specific
HF553_RS00960	COG0625	glutathione transferase activity
HF553_RS00970	COG3276	selenocysteine insertion sequence binding
HF553_RS00975	COG1940	carbohydrate kinase activity
HF553_RS00980	COG1012	belongs to the aldehyde dehydrogenase family
HF553_RS00995	COG0235	Class ii aldolase
HF553_RS01000	COG3623	hexulose-6-phosphate isomerase
HF553_RS01005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HF553_RS01010	COG1070	Carbohydrate kinase
HF553_RS01015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HF553_RS01020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HF553_RS01025	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HF553_RS01035	COG2731	YhcH YjgK YiaL family protein
HF553_RS01045	COG1414	Transcriptional regulator
HF553_RS01050	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HF553_RS01055	COG3977	Valine--pyruvate aminotransferase
HF553_RS01060	COG0366	Alpha amylase catalytic
HF553_RS01065	COG2992	FlgJ-related protein
HF553_RS01070	COG1609	Transcriptional regulator
HF553_RS01070	COG2207	Transcriptional regulator
HF553_RS01075	COG2115	Belongs to the xylose isomerase family
HF553_RS01080	COG1070	Carbohydrate kinase
HF553_RS01085	COG4682	membrane
HF553_RS01090	COG3274	enterobacterial common antigen metabolic process
HF553_RS01120	COG1278	Cold shock
HF553_RS01125	COG2944	sequence-specific DNA binding
HF553_RS01140	COG2885	chlorophyll binding
HF553_RS01145	COG0243	molybdopterin cofactor binding
HF553_RS01150	COG0456	acetyltransferase
HF553_RS01155	COG2818	Glycosylase
HF553_RS01160	COG5571	outer membrane autotransporter
HF553_RS01190	COG1609	Transcriptional regulator
HF553_RS01205	COG0747	negative chemotaxis
HF553_RS01210	COG0601	transmembrane transport
HF553_RS01215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HF553_RS01220	COG0444	Belongs to the ABC transporter superfamily
HF553_RS01225	COG4608	Belongs to the ABC transporter superfamily
HF553_RS01230	COG0814	amino acid
HF553_RS01275	COG1215	transferase activity, transferring glycosyl groups
HF553_RS01290	COG2199	diguanylate cyclase activity
HF553_RS01290	COG2200	EAL domain
HF553_RS01305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HF553_RS01310	COG2200	EAL domain
HF553_RS01315	COG2982	Protein involved in outer membrane biogenesis
HF553_RS01320	COG0477	Major facilitator Superfamily
HF553_RS01325	COG1295	ribonuclease BN
HF553_RS01330	COG0583	DNA-binding transcription factor activity
HF553_RS01335	COG2197	response regulator
HF553_RS01355	COG2188	Transcriptional regulator
HF553_RS01360	COG2222	sugar isomerase
HF553_RS01365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HF553_RS01370	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HF553_RS01380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HF553_RS01385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HF553_RS01390	COG0671	phosphoesterase, PA-phosphatase related
HF553_RS01420	COG0306	phosphate transporter
HF553_RS01425	COG2081	HI0933 family
HF553_RS01430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HF553_RS01435	COG0842	Transport permease protein
HF553_RS01435	COG1129	ABC transporter
HF553_RS01440	COG0842	Transport permease protein
HF553_RS01455	COG0628	permease
HF553_RS01470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HF553_RS01490	COG3714	YhhN family
HF553_RS01500	COG3776	membrane
HF553_RS01505	COG0742	ribosomal rna small subunit methyltransferase
HF553_RS01510	COG0552	protein localization to endoplasmic reticulum
HF553_RS01515	COG2884	Cell division ATP-binding protein ftsE
HF553_RS01520	COG2177	Part of the ABC transporter FtsEX involved in
HF553_RS01595	COG0584	glycerophosphoryl diester phosphodiesterase
HF553_RS01605	COG0405	Gamma-glutamyltransferase
HF553_RS01610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HF553_RS01625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HF553_RS01630	COG1247	-acetyltransferase
HF553_RS01635	COG0673	inositol 2-dehydrogenase activity
HF553_RS01640	COG1741	Belongs to the pirin family
HF553_RS01645	COG1609	Transcriptional regulator
HF553_RS01650	COG3265	gluconokinase activity
HF553_RS01655	COG2610	gluconate transmembrane transporter activity
HF553_RS01670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HF553_RS01690	COG0058	SHG alpha-glucan phosphorylase activity
HF553_RS01695	COG1414	Transcriptional regulator
HF553_RS01700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HF553_RS01705	COG0129	dihydroxy-acid dehydratase activity
HF553_RS01715	COG0371	Dehydrogenase
HF553_RS01730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HF553_RS01745	COG1349	DNA-binding transcription factor activity
HF553_RS01755	COG0058	SHG alpha-glucan phosphorylase activity
HF553_RS01760	COG1640	4-alpha-glucanotransferase
HF553_RS01765	COG2610	gluconate transmembrane transporter activity
HF553_RS01775	COG1040	competence protein
HF553_RS01785	COG5464	transposase or invertase
HF553_RS01800	COG1918	ferrous iron import across plasma membrane
HF553_RS01805	COG2183	response to ionizing radiation
HF553_RS01810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HF553_RS01815	COG0745	RESPONSE REGULATOR receiver
HF553_RS01830	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HF553_RS01840	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HF553_RS01845	COG1011	Hydrolase
HF553_RS01855	COG0494	nUDIX hydrolase
HF553_RS01860	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HF553_RS01865	COG4972	Pilus assembly protein
HF553_RS01870	COG3166	PFAM Fimbrial assembly family protein
HF553_RS01885	COG4796	Type ii and iii secretion system protein
HF553_RS01900	COG3266	domain, Protein
HF553_RS01905	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HF553_RS01910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HF553_RS01950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HF553_RS01960	COG0738	Major facilitator superfamily
HF553_RS01990	COG1289	transmembrane transporter activity
HF553_RS02000	COG1765	OsmC-like protein
HF553_RS02005	COG3954	Phosphoribulokinase
HF553_RS02015	COG0429	hydrolase of the alpha beta-hydrolase fold
HF553_RS02030	COG0488	(ABC) transporter
HF553_RS02045	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HF553_RS02050	COG1047	Peptidyl-prolyl cis-trans
HF553_RS02060	COG0545	Peptidyl-prolyl cis-trans isomerase
HF553_RS02065	COG2964	Protein conserved in bacteria
HF553_RS02120	COG0051	transcription antitermination factor activity, RNA binding
HF553_RS02145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HF553_RS02225	COG0201	protein transport
HF553_RS02265	COG0789	Transcriptional regulator
HF553_RS02270	COG3036	rescue of stalled ribosome
HF553_RS02300	COG0758	DNA mediated transformation
HF553_RS02310	COG0551	DNA topoisomerase type I activity
HF553_RS02330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HF553_RS02375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HF553_RS02380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HF553_RS02385	COG1309	transcriptional regulator
HF553_RS02400	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HF553_RS02425	COG4145	pantothenate transmembrane transporter activity
HF553_RS02430	COG3924	membrane
HF553_RS02435	COG0439	Biotin carboxylase
HF553_RS02440	COG0511	ligase activity, forming carbon-carbon bonds
HF553_RS02455	COG0604	alcohol dehydrogenase
HF553_RS02460	COG2200	EAL domain
HF553_RS02460	COG2199	diguanylate cyclase activity
HF553_RS02465	COG1077	Cell shape determining protein MreB Mrl
HF553_RS02470	COG1792	Involved in formation and maintenance of cell shape
HF553_RS02475	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HF553_RS02485	COG1530	ribonuclease E activity
HF553_RS02490	COG3164	Protein of unknown function
HF553_RS02495	COG0312	modulator of DNA gyrase
HF553_RS02500	COG0583	DNA-binding transcription factor activity
HF553_RS02525	COG2732	(Barnase) inhibitor
HF553_RS02550	COG2188	Transcriptional regulator
HF553_RS02560	COG0471	metal ion transport
HF553_RS02565	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HF553_RS02570	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HF553_RS02575	COG3630	sodium ion export across plasma membrane
HF553_RS02580	COG0511	ligase activity, forming carbon-carbon bonds
HF553_RS02580	COG5016	pyruvate
HF553_RS02585	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HF553_RS02600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HF553_RS02605	COG3105	Protein conserved in bacteria
HF553_RS02610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HF553_RS02630	COG0625	glutathione transferase activity
HF553_RS02635	COG2969	positive regulation of protein catabolic process
HF553_RS02665	COG2731	YhcH YjgK YiaL family protein
HF553_RS02670	COG0402	S-adenosylhomocysteine deaminase activity
HF553_RS02675	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HF553_RS02680	COG4804	nuclease activity
HF553_RS02685	COG0493	'glutamate synthase
HF553_RS02690	COG0069	glutamate synthase activity
HF553_RS02690	COG0070	glutamate synthase
HF553_RS02690	COG0067	glutamate synthase
HF553_RS02695	COG1242	4 iron, 4 sulfur cluster binding
HF553_RS02700	COG5002	protein histidine kinase activity
HF553_RS02700	COG2198	Histidine kinase
HF553_RS02700	COG0784	Response regulator, receiver
HF553_RS02705	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HF553_RS02715	COG0515	serine threonine protein kinase
HF553_RS02720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS02745	COG1137	ATPase activity
HF553_RS02750	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HF553_RS02755	COG3117	lipopolysaccharide transmembrane transporter activity
HF553_RS02760	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HF553_RS02770	COG0530	calcium, potassium:sodium antiporter activity
HF553_RS02775	COG1127	ABC transporter
HF553_RS02780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HF553_RS02785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HF553_RS02790	COG2854	intermembrane phospholipid transfer
HF553_RS02795	COG3113	response to antibiotic
HF553_RS02800	COG5007	Belongs to the BolA IbaG family
HF553_RS02810	COG3423	Transcriptional regulator
HF553_RS02815	COG0142	geranyltranstransferase activity
HF553_RS02830	COG0697	spore germination
HF553_RS02840	COG2027	D-alanyl-D-alanine carboxypeptidase
HF553_RS02850	COG1534	Rna-binding protein
HF553_RS02865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HF553_RS02875	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HF553_RS02945	COG0513	Belongs to the DEAD box helicase family
HF553_RS02950	COG0814	amino acid
HF553_RS02960	COG3034	peptidoglycan biosynthetic process
HF553_RS02965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HF553_RS02970	COG0826	peptidase U32
HF553_RS02975	COG0826	peptidase U32
HF553_RS02980	COG3154	lipid carrier protein
HF553_RS02985	COG3153	acetyltransferase
HF553_RS03000	COG0693	protein deglycase activity
HF553_RS03005	COG0702	epimerase
HF553_RS03010	COG2823	Periplasmic or secreted lipoprotein
HF553_RS03025	COG3107	peptidoglycan biosynthetic process
HF553_RS03030	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HF553_RS03040	COG1063	alcohol dehydrogenase
HF553_RS03045	COG3775	system Galactitol-specific IIC component
HF553_RS03050	COG3414	Phosphotransferase system galactitol-specific IIB component
HF553_RS03055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS03070	COG2721	sulfolactate sulfo-lyase activity
HF553_RS03080	COG2084	Dehydrogenase
HF553_RS03085	COG1929	Belongs to the glycerate kinase type-1 family
HF553_RS03095	COG0583	DNA-binding transcription factor activity
HF553_RS03110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HF553_RS03115	COG1882	Formate acetyltransferase
HF553_RS03120	COG1760	l-serine dehydratase
HF553_RS03125	COG0814	amino acid
HF553_RS03140	COG1741	Belongs to the pirin family
HF553_RS03145	COG0583	DNA-binding transcription factor activity
HF553_RS03150	COG3152	Membrane
HF553_RS03155	COG0435	Glutathione S-transferase
HF553_RS03160	COG2259	Doxx family
HF553_RS03170	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HF553_RS03175	COG4575	ribosome binding
HF553_RS03180	COG1422	Protein of unknown function (DUF1090)
HF553_RS03190	COG0586	Pfam SNARE associated Golgi protein
HF553_RS03205	COG0673	inositol 2-dehydrogenase activity
HF553_RS03210	COG2949	membrane
HF553_RS03215	COG1451	nucleotide metabolic process
HF553_RS03225	COG1902	pentaerythritol trinitrate reductase activity
HF553_RS03225	COG0446	pyridine nucleotide-disulphide oxidoreductase
HF553_RS03235	COG0840	transmembrane signaling receptor activity
HF553_RS03245	COG0840	transmembrane signaling receptor activity
HF553_RS03250	COG1695	Transcriptional regulator
HF553_RS03255	COG2375	cellular response to nickel ion
HF553_RS03260	COG4974	Belongs to the 'phage' integrase family
HF553_RS03305	COG2176	DNA-directed DNA polymerase activity
HF553_RS03305	COG5002	protein histidine kinase activity
HF553_RS03335	COG4695	Portal protein
HF553_RS03430	COG5301	cellulose 1,4-beta-cellobiosidase activity
HF553_RS03485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HF553_RS03565	COG3344	reverse transcriptase
HF553_RS03575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HF553_RS03580	COG1061	Type III restriction enzyme res subunit
HF553_RS03585	COG1002	Type II restriction enzyme, methylase subunits
HF553_RS03615	COG3468	outer membrane autotransporter barrel domain protein
HF553_RS03635	COG2003	Belongs to the UPF0758 family
HF553_RS03675	COG0582	viral genome integration into host DNA
HF553_RS03710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HF553_RS03745	COG4695	Portal protein
HF553_RS03830	COG5301	cellulose 1,4-beta-cellobiosidase activity
HF553_RS03905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HF553_RS03930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HF553_RS03945	COG4991	sh3 domain protein
HF553_RS03950	COG3025	triphosphatase activity
HF553_RS03970	COG2268	Band 7 protein
HF553_RS03975	COG1585	Membrane protein implicated in regulation of membrane protease activity
HF553_RS04015	COG3384	dioxygenase
HF553_RS04020	COG0754	glutathionylspermidine amidase activity
HF553_RS04035	COG0494	nUDIX hydrolase
HF553_RS04040	COG3151	Protein conserved in bacteria
HF553_RS04045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HF553_RS04050	COG3150	esterase
HF553_RS04060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HF553_RS04065	COG2249	NAD(P)H dehydrogenase (quinone) activity
HF553_RS04080	COG3111	PFAM Bacterial OB fold (BOF) protein
HF553_RS04085	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HF553_RS04135	COG0471	metal ion transport
HF553_RS04145	COG1979	alcohol dehydrogenase
HF553_RS04150	COG2207	Transcriptional regulator
HF553_RS04170	COG0848	biopolymer transport protein
HF553_RS04175	COG1028	Short-chain dehydrogenase reductase Sdr
HF553_RS04200	COG0840	transmembrane signaling receptor activity
HF553_RS04210	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HF553_RS04215	COG0437	4 iron, 4 sulfur cluster binding
HF553_RS04220	COG5557	Pfam Polysulphide reductase, NrfD
HF553_RS04225	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HF553_RS04230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HF553_RS04235	COG1773	rubredoxin
HF553_RS04245	COG0298	carbon dioxide binding
HF553_RS04260	COG0625	glutathione transferase activity
HF553_RS04265	COG0754	glutathionylspermidine amidase activity
HF553_RS04280	COG0246	Mannitol dehydrogenase
HF553_RS04290	COG2271	Major facilitator Superfamily
HF553_RS04315	COG1012	belongs to the aldehyde dehydrogenase family
HF553_RS04320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HF553_RS04330	COG0531	amino acid
HF553_RS04345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HF553_RS04370	COG3609	addiction module antidote protein, CC2985 family
HF553_RS04425	COG2003	Belongs to the UPF0758 family
HF553_RS04450	COG3596	GTP binding
HF553_RS04605	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HF553_RS04640	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HF553_RS04655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HF553_RS04700	COG2194	sulfuric ester hydrolase activity
HF553_RS04745	COG0582	viral genome integration into host DNA
HF553_RS04755	COG1811	Na channel or pump
HF553_RS04760	COG1982	Orn Lys Arg decarboxylase major
HF553_RS04765	COG2211	Major facilitator Superfamily
HF553_RS04790	COG3171	Protein conserved in bacteria
HF553_RS04800	COG0252	asparaginase activity
HF553_RS04810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HF553_RS04815	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HF553_RS04825	COG0762	integral membrane protein
HF553_RS04830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HF553_RS04835	COG2805	Type II/IV secretion system protein
HF553_RS04860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HF553_RS04865	COG2356	endonuclease I
HF553_RS04875	COG2814	Major facilitator Superfamily
HF553_RS04900	COG1166	arginine decarboxylase activity
HF553_RS04910	COG0501	Belongs to the peptidase M48B family
HF553_RS04915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HF553_RS04920	COG1122	ATPase activity
HF553_RS04925	COG1122	ATPase activity
HF553_RS04955	COG0191	fructose-bisphosphate aldolase activity
HF553_RS04960	COG0668	transmembrane transport
HF553_RS04970	COG2968	Membrane
HF553_RS04990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HF553_RS04995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HF553_RS05015	COG0006	proline dipeptidase activity
HF553_RS05020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HF553_RS05025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HF553_RS05050	COG2723	6-phospho-beta-galactosidase activity
HF553_RS05060	COG1272	protein, Hemolysin III
HF553_RS05120	COG4942	peptidase
HF553_RS05165	COG3188	usher protein
HF553_RS05200	COG0814	amino acid
HF553_RS05215	COG0183	Belongs to the thiolase family
HF553_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
HF553_RS05230	COG2814	Major facilitator Superfamily
HF553_RS05235	COG1794	racemase activity, acting on amino acids and derivatives
HF553_RS05240	COG0583	DNA-binding transcription factor activity
HF553_RS05250	COG1609	Transcriptional regulator
HF553_RS05270	COG0667	Aldo Keto reductase
HF553_RS05280	COG0861	Integral membrane protein TerC family
HF553_RS05310	COG2165	general secretion pathway protein
HF553_RS05315	COG4795	General secretion pathway protein
HF553_RS05325	COG4967	type IV pilus modification protein PilV
HF553_RS05330	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HF553_RS05335	COG1025	Belongs to the peptidase M16 family
HF553_RS05340	COG1074	ATP-dependent DNA helicase activity
HF553_RS05345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HF553_RS05350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HF553_RS05350	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HF553_RS05355	COG0860	N-Acetylmuramoyl-L-alanine amidase
HF553_RS05370	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HF553_RS05375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HF553_RS05380	COG2962	Rard protein
HF553_RS05385	COG2166	iron-sulfur cluster assembly
HF553_RS05390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HF553_RS05400	COG0583	DNA-binding transcription factor activity
HF553_RS05405	COG2363	Small membrane protein
HF553_RS05415	COG1349	DNA-binding transcription factor activity
HF553_RS05435	COG0738	Major facilitator superfamily
HF553_RS05440	COG0235	Class ii aldolase
HF553_RS05445	COG1454	alcohol dehydrogenase
HF553_RS05455	COG1760	l-serine dehydratase
HF553_RS05460	COG0814	amino acid
HF553_RS05465	COG1611	Belongs to the LOG family
HF553_RS05490	COG0716	FMN binding
HF553_RS05500	COG2271	Major facilitator Superfamily
HF553_RS05505	COG4948	Mandelate Racemase Muconate Lactonizing
HF553_RS05510	COG4948	Mandelate Racemase Muconate Lactonizing
HF553_RS05515	COG1929	Belongs to the glycerate kinase type-1 family
HF553_RS05520	COG3850	Histidine kinase
HF553_RS05520	COG4999	Histidine kinase
HF553_RS05520	COG3437	response regulator, receiver
HF553_RS05520	COG2205	protein histidine kinase activity
HF553_RS05530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HF553_RS05535	COG3609	addiction module antidote protein, CC2985 family
HF553_RS05565	COG3539	Fimbrial protein
HF553_RS05570	COG3121	Chaperone
HF553_RS05575	COG3188	usher protein
HF553_RS05580	COG3539	Fimbrial protein
HF553_RS05585	COG3956	TIGRFAM MazG family protein
HF553_RS05600	COG0602	queuosine metabolic process
HF553_RS05605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HF553_RS05605	COG0321	lipoyl(octanoyl) transferase activity
HF553_RS05610	COG0720	synthase
HF553_RS05635	COG1203	CRISPR-associated helicase, Cas3
HF553_RS05650	COG1857	crispr-associated protein
HF553_RS05665	COG1518	maintenance of DNA repeat elements
HF553_RS05670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HF553_RS05675	COG2234	aminopeptidase activity
HF553_RS05745	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HF553_RS05750	COG0163	prenyltransferase activity
HF553_RS05760	COG1349	DNA-binding transcription factor activity
HF553_RS05765	COG2084	Dehydrogenase
HF553_RS05775	COG0235	Class ii aldolase
HF553_RS05780	COG3622	Belongs to the hyi family
HF553_RS05785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HF553_RS05790	COG2610	gluconate transmembrane transporter activity
HF553_RS05800	COG0477	Major facilitator Superfamily
HF553_RS05880	COG2207	Transcriptional regulator
HF553_RS05970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HF553_RS06050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HF553_RS06055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HF553_RS06060	COG1121	(ABC) transporter
HF553_RS06080	COG0309	Hydrogenase expression formation protein (HypE)
HF553_RS06085	COG0409	Hydrogenase expression formation protein
HF553_RS06090	COG0298	carbon dioxide binding
HF553_RS06095	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HF553_RS06110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HF553_RS06115	COG0651	ATP synthesis coupled electron transport
HF553_RS06120	COG0650	Formate hydrogenlyase subunit 4
HF553_RS06125	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HF553_RS06125	COG3261	NADH dehydrogenase
HF553_RS06130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HF553_RS06135	COG3260	NADH ubiquinone oxidoreductase 20
HF553_RS06145	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HF553_RS06155	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HF553_RS06160	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HF553_RS06185	COG1349	DNA-binding transcription factor activity
HF553_RS06190	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
HF553_RS06205	COG3732	PTS system glucitol sorbitol-specific
HF553_RS06210	COG3730	PTS system glucitol sorbitol-specific
HF553_RS06215	COG2951	lytic endotransglycosylase activity
HF553_RS06220	COG1546	Belongs to the CinA family
HF553_RS06240	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HF553_RS06270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HF553_RS06275	COG1238	metal cluster binding
HF553_RS06295	COG2814	Major facilitator Superfamily
HF553_RS06300	COG1566	PFAM secretion protein HlyD family protein
HF553_RS06305	COG1846	Transcriptional regulator
HF553_RS06310	COG2814	Major facilitator Superfamily
HF553_RS06350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HF553_RS06360	COG4575	ribosome binding
HF553_RS06385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HF553_RS06390	COG0640	Transcriptional regulator
HF553_RS06395	COG0401	homolog of Blt101
HF553_RS06400	COG1652	LysM domain
HF553_RS06405	COG1802	Transcriptional regulator
HF553_RS06410	COG1113	amino acid transport
HF553_RS06415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HF553_RS06420	COG1012	belongs to the aldehyde dehydrogenase family
HF553_RS06425	COG0579	oxidoreductase
HF553_RS06455	COG0642	Histidine kinase
HF553_RS06460	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HF553_RS06470	COG2990	Protein conserved in bacteria
HF553_RS06490	COG2819	hydrolase of the alpha beta superfamily
HF553_RS06555	COG0582	viral genome integration into host DNA
HF553_RS06565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HF553_RS06590	COG2867	negative regulation of translational initiation
HF553_RS06605	COG0497	DNA recombination
HF553_RS06625	COG4536	flavin adenine dinucleotide binding
HF553_RS06630	COG4137	Cytochrome C assembly protein
HF553_RS06635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HF553_RS06660	COG2199	diguanylate cyclase activity
HF553_RS06675	COG0287	Prephenate dehydrogenase
HF553_RS06675	COG1605	Chorismate mutase
HF553_RS06685	COG1605	Chorismate mutase
HF553_RS06685	COG0077	Prephenate dehydratase
HF553_RS06695	COG4974	Belongs to the 'phage' integrase family
HF553_RS06735	COG4695	Portal protein
HF553_RS06825	COG5301	cellulose 1,4-beta-cellobiosidase activity
HF553_RS06855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HF553_RS06860	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HF553_RS06875	COG0542	response to heat
HF553_RS06905	COG0477	Major facilitator Superfamily
HF553_RS06910	COG5544	Lipoprotein
HF553_RS06915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HF553_RS06930	COG3118	belongs to the thioredoxin family
HF553_RS06935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HF553_RS06955	COG0583	DNA-binding transcription factor activity
HF553_RS06960	COG0513	Belongs to the DEAD box helicase family
HF553_RS06995	COG3086	response to oxidative stress
HF553_RS07035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HF553_RS07040	COG0583	DNA-binding transcription factor activity
HF553_RS07045	COG2223	nitrite transmembrane transporter activity
HF553_RS07050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HF553_RS07055	COG1737	Transcriptional regulator
HF553_RS07065	COG1263	PTS System
HF553_RS07065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HF553_RS07070	COG0560	Phosphoserine phosphatase
HF553_RS07095	COG2205	protein histidine kinase activity
HF553_RS07100	COG3170	Tfp pilus assembly protein FimV
HF553_RS07105	COG2204	response regulator
HF553_RS07110	COG0347	Belongs to the P(II) protein family
HF553_RS07115	COG3104	oligopeptide transport
HF553_RS07125	COG0531	amino acid
HF553_RS07130	COG3710	Transcriptional regulator
HF553_RS07140	COG1017	nitric oxide dioxygenase activity
HF553_RS07140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HF553_RS07150	COG2814	Major facilitator Superfamily
HF553_RS07155	COG3711	transcriptional antiterminator
HF553_RS07165	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HF553_RS07210	COG0822	iron-sulfur transferase activity
HF553_RS07230	COG0633	Ferredoxin
HF553_RS07235	COG2975	iron-sulfur cluster assembly
HF553_RS07255	COG2897	thiosulfate sulfurtransferase activity
HF553_RS07260	COG2373	Large extracellular alpha-helical protein
HF553_RS07265	COG4953	penicillin-binding protein 1C
HF553_RS07270	COG0243	molybdopterin cofactor binding
HF553_RS07275	COG0437	4 iron, 4 sulfur cluster binding
HF553_RS07315	COG2976	Protein conserved in bacteria
HF553_RS07330	COG1645	bacterial-type flagellum-dependent swarming motility
HF553_RS07370	COG0517	IMP dehydrogenase activity
HF553_RS07370	COG0516	GMP reductase activity
HF553_RS07395	COG3133	Outer membrane lipoprotein
HF553_RS07410	COG2200	EAL domain
HF553_RS07425	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HF553_RS07440	COG2233	PERMEase
HF553_RS07450	COG1393	Belongs to the ArsC family
HF553_RS07460	COG0628	permease
HF553_RS07465	COG3835	regulator
HF553_RS07470	COG2610	gluconate transmembrane transporter activity
HF553_RS07475	COG1929	Belongs to the glycerate kinase type-1 family
HF553_RS07480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HF553_RS07485	COG2716	regulation of RNA biosynthetic process
HF553_RS07490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HF553_RS07495	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HF553_RS07505	COG2321	neutral zinc metallopeptidase
HF553_RS07525	COG1393	Belongs to the ArsC family
HF553_RS07535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HF553_RS07540	COG3850	Histidine kinase
HF553_RS07545	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HF553_RS07545	COG0493	'glutamate synthase
HF553_RS07560	COG5342	invasion associated locus B
HF553_RS07570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HF553_RS07695	COG2837	iron assimilation
HF553_RS07715	COG4208	sulfate ABC transporter
HF553_RS07720	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HF553_RS07765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS07790	COG3530	Putative quorum-sensing-regulated virulence factor
HF553_RS07795	COG0385	Bile acid
HF553_RS07800	COG0583	DNA-binding transcription factor activity
HF553_RS07810	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HF553_RS07815	COG2211	Major facilitator Superfamily
HF553_RS07825	COG0583	DNA-binding transcription factor activity
HF553_RS07855	COG3415	Transposase
HF553_RS07860	COG3415	Transposase
HF553_RS07875	COG2199	diguanylate cyclase activity
HF553_RS07875	COG2200	EAL domain
HF553_RS07880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HF553_RS07895	COG0667	Aldo Keto reductase
HF553_RS07900	COG3961	Belongs to the TPP enzyme family
HF553_RS07920	COG0436	Aminotransferase
HF553_RS07930	COG1560	Kdo2-lipid A biosynthetic process
HF553_RS07980	COG2755	lipolytic protein G-D-S-L family
HF553_RS07980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HF553_RS07985	COG0463	Glycosyl transferase, family 2
HF553_RS07990	COG2246	polysaccharide biosynthetic process
HF553_RS08010	COG2116	formate transmembrane transporter activity
HF553_RS08025	COG3691	Protein conserved in bacteria
HF553_RS08040	COG2062	phosphohistidine phosphatase, SixA
HF553_RS08065	COG0730	response to heat
HF553_RS08070	COG3101	peptidyl-lysine hydroxylation
HF553_RS08085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HF553_RS08125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HF553_RS08135	COG0586	Pfam SNARE associated Golgi protein
HF553_RS08145	COG0285	dihydrofolate synthase activity
HF553_RS08150	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HF553_RS08155	COG1286	toxin biosynthetic process
HF553_RS08160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HF553_RS08165	COG3829	transcription factor binding
HF553_RS08175	COG0531	amino acid
HF553_RS08180	COG3457	Alanine racemase
HF553_RS08185	COG0833	amino acid
HF553_RS08220	COG1090	epimerase
HF553_RS08225	COG0625	glutathione transferase activity
HF553_RS08230	COG0625	glutathione transferase activity
HF553_RS08235	COG0622	Phosphoesterase
HF553_RS08245	COG1609	Transcriptional regulator
HF553_RS08250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS08260	COG3037	sugar-specific permease SgaT UlaA
HF553_RS08265	COG3959	Transketolase, thiamine diphosphate binding domain
HF553_RS08270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HF553_RS08275	COG1288	antiporter activity
HF553_RS08300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HF553_RS08305	COG0490	domain, Protein
HF553_RS08305	COG0471	metal ion transport
HF553_RS08315	COG0436	Aminotransferase
HF553_RS08320	COG0583	DNA-binding transcription factor activity
HF553_RS08370	COG0839	Belongs to the complex I subunit 6 family
HF553_RS08380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HF553_RS08385	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HF553_RS08395	COG0835	chemotaxis
HF553_RS08395	COG0784	Response regulator, receiver
HF553_RS08405	COG2153	protein acetylation
HF553_RS08410	COG4575	ribosome binding
HF553_RS08415	COG1169	isochorismate synthase
HF553_RS08510	COG0247	lactate metabolic process
HF553_RS08520	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HF553_RS08525	COG2271	Major facilitator Superfamily
HF553_RS08530	COG0584	glycerophosphoryl diester phosphodiesterase
HF553_RS08535	COG0583	DNA-binding transcription factor activity
HF553_RS08540	COG2814	Major facilitator Superfamily
HF553_RS08545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HF553_RS08605	COG2198	Histidine kinase
HF553_RS08605	COG0642	Histidine kinase
HF553_RS08630	COG4615	Cyclic peptide transporter
HF553_RS08640	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HF553_RS08640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HF553_RS08645	COG3062	negative regulation of establishment of protein localization
HF553_RS08655	COG0437	4 iron, 4 sulfur cluster binding
HF553_RS08660	COG0348	domain, Protein
HF553_RS08665	COG3043	anaerobic respiration
HF553_RS08670	COG3005	denitrification pathway
HF553_RS08680	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HF553_RS08685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HF553_RS08690	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HF553_RS08700	COG1138	Cytochrome C-type biogenesis protein
HF553_RS08710	COG4235	cytochrome complex assembly
HF553_RS08710	COG3088	subunit of a heme lyase
HF553_RS08715	COG2197	response regulator
HF553_RS08780	COG1061	Type III restriction enzyme res subunit
HF553_RS08790	COG2814	Major facilitator Superfamily
HF553_RS08800	COG4172	Belongs to the ABC transporter superfamily
HF553_RS08805	COG4239	(ABC) transporter, permease
HF553_RS08810	COG4174	ABC transporter (Permease)
HF553_RS08815	COG4166	transmembrane transport
HF553_RS08820	COG2200	EAL domain
HF553_RS08825	COG0791	NLP P60 protein
HF553_RS08830	COG0671	phosphoesterase, PA-phosphatase related
HF553_RS08835	COG0523	cobalamin synthesis protein
HF553_RS08870	COG1105	Belongs to the carbohydrate kinase PfkB family
HF553_RS08875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HF553_RS08875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HF553_RS08875	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HF553_RS08880	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HF553_RS08885	COG2855	membrane
HF553_RS08890	COG0583	DNA-binding transcription factor activity
HF553_RS08895	COG0833	amino acid
HF553_RS08900	COG4771	TonB-dependent receptor
HF553_RS08905	COG2271	Major facilitator Superfamily
HF553_RS08910	COG0560	Phosphoserine phosphatase
HF553_RS08915	COG1760	l-serine dehydratase
HF553_RS08935	COG2311	Membrane
HF553_RS08975	COG2949	membrane
HF553_RS08985	COG1346	cytolysis
HF553_RS09000	COG2271	Major facilitator Superfamily
HF553_RS09015	COG0625	glutathione transferase activity
HF553_RS09020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HF553_RS09035	COG1538	Outer membrane efflux protein
HF553_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
HF553_RS09045	COG0586	Pfam SNARE associated Golgi protein
HF553_RS09055	COG1686	Belongs to the peptidase S11 family
HF553_RS09060	COG0277	FAD linked oxidase domain protein
HF553_RS09070	COG1732	Glycine betaine
HF553_RS09075	COG1174	glycine betaine transport
HF553_RS09080	COG1125	glycine betaine transport
HF553_RS09085	COG1174	glycine betaine transport
HF553_RS09100	COG3275	phosphorelay sensor kinase activity
HF553_RS09110	COG4807	Protein conserved in bacteria
HF553_RS09120	COG4808	Protein conserved in bacteria
HF553_RS09145	COG3121	Chaperone
HF553_RS09150	COG3188	usher protein
HF553_RS09160	COG5455	response to cobalt ion
HF553_RS09175	COG2188	Transcriptional regulator
HF553_RS09180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HF553_RS09185	COG1397	ADP-ribosylglycohydrolase
HF553_RS09190	COG2211	Major facilitator Superfamily
HF553_RS09195	COG1830	Aldolase
HF553_RS09245	COG3209	COG3209 Rhs family protein
HF553_RS09260	COG3209	COG3209 Rhs family protein
HF553_RS09265	COG3209	COG3209 Rhs family protein
HF553_RS09275	COG1413	lyase activity
HF553_RS09280	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HF553_RS09325	COG0745	RESPONSE REGULATOR receiver
HF553_RS09330	COG2205	protein histidine kinase activity
HF553_RS09360	COG0443	Heat shock 70 kDa protein
HF553_RS09365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HF553_RS09370	COG5001	Diguanylate cyclase
HF553_RS09370	COG5002	protein histidine kinase activity
HF553_RS09370	COG3447	MASE1 domain protein
HF553_RS09385	COG2982	Protein involved in outer membrane biogenesis
HF553_RS09390	COG1253	flavin adenine dinucleotide binding
HF553_RS09410	COG0463	Glycosyl transferase, family 2
HF553_RS09415	COG1045	serine acetyltransferase
HF553_RS09420	COG0438	transferase activity, transferring glycosyl groups
HF553_RS09430	COG1216	Glycosyl transferase, family 2
HF553_RS09435	COG0110	maltose O-acetyltransferase activity
HF553_RS09440	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HF553_RS09445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HF553_RS09455	COG0297	glycogen (starch) synthase activity
HF553_RS09470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HF553_RS09475	COG2244	polysaccharide biosynthetic process
HF553_RS09480	COG2327	Polysaccharide pyruvyl transferase
HF553_RS09525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HF553_RS09640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HF553_RS09645	COG0583	DNA-binding transcription factor activity
HF553_RS09655	COG0531	amino acid
HF553_RS09660	COG2925	Exonuclease
HF553_RS09700	COG1289	transmembrane transporter activity
HF553_RS09735	COG4656	Part of a membrane complex involved in electron transport
HF553_RS09740	COG1012	belongs to the aldehyde dehydrogenase family
HF553_RS09740	COG1454	alcohol dehydrogenase
HF553_RS09770	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HF553_RS09830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HF553_RS09900	COG1122	ATPase activity
HF553_RS09935	COG0534	Mate efflux family protein
HF553_RS09945	COG0582	viral genome integration into host DNA
HF553_RS09955	COG3423	Transcriptional regulator
HF553_RS09990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HF553_RS09995	COG2249	NAD(P)H dehydrogenase (quinone) activity
HF553_RS10000	COG1733	regulation of RNA biosynthetic process
HF553_RS10160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HF553_RS10170	COG0582	viral genome integration into host DNA
HF553_RS10200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HF553_RS10210	COG1418	mRNA catabolic process
HF553_RS10215	COG0270	DNA (cytosine-5-)-methyltransferase activity
HF553_RS10220	COG3727	T/G mismatch-specific endonuclease activity
HF553_RS10225	COG0697	spore germination
HF553_RS10230	COG2354	Protein conserved in bacteria
HF553_RS10235	COG5475	Uncharacterized small protein (DUF2158)
HF553_RS10340	COG0425	Belongs to the sulfur carrier protein TusA family
HF553_RS10415	COG2197	response regulator
HF553_RS10430	COG2197	response regulator
HF553_RS10475	COG3318	Belongs to the UPF0149 family
HF553_RS10475	COG3012	SEC-C Motif Domain Protein
HF553_RS10480	COG0814	amino acid
HF553_RS10490	COG1528	Iron-storage protein
HF553_RS10505	COG1528	Iron-storage protein
HF553_RS10610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HF553_RS10625	COG3102	Protein conserved in bacteria
HF553_RS10645	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HF553_RS10650	COG1801	Protein of unknown function DUF72
HF553_RS10655	COG1335	isochorismatase
HF553_RS10665	COG0494	nUDIX hydrolase
HF553_RS10700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HF553_RS10705	COG1121	(ABC) transporter
HF553_RS10710	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HF553_RS10715	COG0739	heme binding
HF553_RS10720	COG1560	Kdo2-lipid A biosynthetic process
HF553_RS10730	COG1737	Transcriptional regulator
HF553_RS10735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HF553_RS10740	COG0129	dihydroxy-acid dehydratase activity
HF553_RS10745	COG0800	Aldolase
HF553_RS10755	COG3141	response to X-ray
HF553_RS10765	COG2979	Protein of unknown function (DUF533)
HF553_RS10770	COG1770	oligopeptidase
HF553_RS10775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HF553_RS10780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HF553_RS10790	COG2372	response to copper ion
HF553_RS10795	COG1276	copper resistance
HF553_RS10805	COG0582	viral genome integration into host DNA
HF553_RS10870	COG5562	phage envelope protein
HF553_RS10905	COG3008	intermembrane lipid transfer
HF553_RS10910	COG2995	paraquat-inducible protein a
HF553_RS10915	COG1956	GAF domain-containing protein
HF553_RS10935	COG2814	Major facilitator Superfamily
HF553_RS10940	COG1414	Transcriptional regulator
HF553_RS10970	COG0768	penicillin binding
HF553_RS10975	COG2226	methyltransferase
HF553_RS10990	COG3716	PTS system mannose fructose sorbose family IID component
HF553_RS10995	COG3715	PTS system
HF553_RS11000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS11000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HF553_RS11005	COG1253	flavin adenine dinucleotide binding
HF553_RS11010	COG2200	EAL domain
HF553_RS11015	COG1760	l-serine dehydratase
HF553_RS11035	COG0251	oxidation-reduction process
HF553_RS11040	COG1199	ATP-dependent helicase activity
HF553_RS11050	COG3065	identical protein binding
HF553_RS11060	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HF553_RS11070	COG2894	cell division
HF553_RS11085	COG0179	Fumarylacetoacetate (FAA) hydrolase
HF553_RS11125	COG2719	SpoVR family
HF553_RS11145	COG1619	proteins homologs of microcin C7 resistance protein MccF
HF553_RS11170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HF553_RS11180	COG1294	oxidase, subunit
HF553_RS11185	COG1271	oxidase subunit
HF553_RS11190	COG1773	rubredoxin
HF553_RS11195	COG1999	signal sequence binding
HF553_RS11200	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HF553_RS11205	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HF553_RS11225	COG0012	GTP binding
HF553_RS11240	COG0659	secondary active sulfate transmembrane transporter activity
HF553_RS11290	COG0387	Pfam Sodium calcium exchanger
HF553_RS11295	COG4572	Cation transport regulator
HF553_RS11300	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HF553_RS11305	COG4932	domain protein
HF553_RS11310	COG2197	response regulator
HF553_RS11315	COG3850	Histidine kinase
HF553_RS11320	COG2223	nitrite transmembrane transporter activity
HF553_RS11325	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HF553_RS11330	COG1140	nitrate reductase beta subunit
HF553_RS11335	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HF553_RS11340	COG2181	nitrate reductase activity
HF553_RS11370	COG0788	formyltetrahydrofolate deformylase activity
HF553_RS11380	COG1752	Esterase of the alpha-beta hydrolase superfamily
HF553_RS11385	COG0745	RESPONSE REGULATOR receiver
HF553_RS11390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HF553_RS11405	COG1454	alcohol dehydrogenase
HF553_RS11405	COG1012	belongs to the aldehyde dehydrogenase family
HF553_RS11410	COG2095	MarC family integral membrane protein
HF553_RS11440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HF553_RS11460	COG2350	Protein conserved in bacteria
HF553_RS11485	COG0727	PFAM Uncharacterised protein family (UPF0153)
HF553_RS11495	COG3546	catalase activity
HF553_RS11500	COG3685	Protein conserved in bacteria
HF553_RS11505	COG3685	Protein conserved in bacteria
HF553_RS11510	COG3729	General stress protein
HF553_RS11550	COG0009	L-threonylcarbamoyladenylate synthase
HF553_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
HF553_RS11570	COG0616	signal peptide processing
HF553_RS11610	COG0671	phosphoesterase, PA-phosphatase related
HF553_RS11615	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HF553_RS11620	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HF553_RS11640	COG1349	DNA-binding transcription factor activity
HF553_RS11650	COG5001	Diguanylate cyclase
HF553_RS11660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HF553_RS11660	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HF553_RS11755	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HF553_RS11760	COG1842	Phage shock protein A
HF553_RS11770	COG1983	PspC domain protein
HF553_RS11780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HF553_RS11785	COG3106	COG3106 Predicted ATPase
HF553_RS11805	COG4948	Mandelate Racemase Muconate Lactonizing
HF553_RS11810	COG2866	Carboxypeptidase
HF553_RS11815	COG4166	transmembrane transport
HF553_RS11825	COG0583	DNA-binding transcription factor activity
HF553_RS11830	COG0656	L-ascorbic acid biosynthetic process
HF553_RS11835	COG1028	Short-chain dehydrogenase reductase Sdr
HF553_RS11840	COG1309	transcriptional regulator
HF553_RS11875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HF553_RS11895	COG0668	transmembrane transport
HF553_RS11900	COG3182	Iron-regulated membrane protein
HF553_RS11920	COG2840	Smr protein MutS2
HF553_RS11925	COG0840	transmembrane signaling receptor activity
HF553_RS11935	COG0513	Belongs to the DEAD box helicase family
HF553_RS11955	COG2076	Multidrug Resistance protein
HF553_RS11970	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HF553_RS11970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HF553_RS11970	COG1013	pyruvate-flavodoxin oxidoreductase activity
HF553_RS11970	COG0674	pyruvate-flavodoxin oxidoreductase activity
HF553_RS11980	COG3042	response to heat
HF553_RS11985	COG3187	Heat shock protein
HF553_RS11990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HF553_RS11995	COG2911	Protein conserved in bacteria
HF553_RS12005	COG3784	Protein of unknown function (DUF1318)
HF553_RS12020	COG1643	Atp-dependent helicase
HF553_RS12025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HF553_RS12030	COG3038	cytochrome b561
HF553_RS12035	COG0500	methyltransferase
HF553_RS12045	COG0765	amino acid transport
HF553_RS12055	COG0765	amino acid transport
HF553_RS12060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HF553_RS12095	COG0840	transmembrane signaling receptor activity
HF553_RS12100	COG0583	DNA-binding transcription factor activity
HF553_RS12105	COG5383	Protein conserved in bacteria
HF553_RS12110	COG2272	Belongs to the type-B carboxylesterase lipase family
HF553_RS12115	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HF553_RS12125	COG3775	system Galactitol-specific IIC component
HF553_RS12130	COG3414	Phosphotransferase system galactitol-specific IIB component
HF553_RS12140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HF553_RS12145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HF553_RS12150	COG1275	C4-dicarboxylate transporter malic acid transport protein
HF553_RS12155	COG0500	methyltransferase
HF553_RS12165	COG3135	benzoate transporter
HF553_RS12170	COG1396	sequence-specific DNA binding
HF553_RS12175	COG0826	peptidase U32
HF553_RS12200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HF553_RS12205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HF553_RS12245	COG3238	Protein conserved in bacteria
HF553_RS12255	COG2130	NADP-dependent
HF553_RS12260	COG1802	Transcriptional regulator
HF553_RS12265	COG4772	TonB-dependent receptor
HF553_RS12270	COG3391	amine dehydrogenase activity
HF553_RS12300	COG2181	nitrate reductase activity
HF553_RS12305	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HF553_RS12310	COG1140	nitrate reductase beta subunit
HF553_RS12315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HF553_RS12355	COG0437	4 iron, 4 sulfur cluster binding
HF553_RS12360	COG2864	formate dehydrogenase
HF553_RS12365	COG1064	alcohol dehydrogenase
HF553_RS12385	COG1764	response to oxidative stress
HF553_RS12410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HF553_RS12425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HF553_RS12430	COG1757	Na H antiporter
HF553_RS12435	COG1609	Transcriptional regulator
HF553_RS12470	COG0251	oxidation-reduction process
HF553_RS12475	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HF553_RS12500	COG2271	Major facilitator Superfamily
HF553_RS12505	COG1063	alcohol dehydrogenase
HF553_RS12510	COG2186	Transcriptional regulator
HF553_RS12520	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HF553_RS12525	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HF553_RS12550	COG1773	rubredoxin
HF553_RS12575	COG3781	membrane
HF553_RS12590	COG1012	belongs to the aldehyde dehydrogenase family
HF553_RS12595	COG0583	DNA-binding transcription factor activity
HF553_RS12630	COG2814	Major facilitator Superfamily
HF553_RS12640	COG3111	PFAM Bacterial OB fold (BOF) protein
HF553_RS12645	COG1546	Belongs to the CinA family
HF553_RS12650	COG3729	General stress protein
HF553_RS12660	COG4221	oxidoreductase activity
HF553_RS12665	COG1802	Transcriptional regulator
HF553_RS12675	COG0246	Mannitol dehydrogenase
HF553_RS12680	COG0477	Major facilitator Superfamily
HF553_RS12685	COG1063	alcohol dehydrogenase
HF553_RS12705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HF553_RS12720	COG0243	molybdopterin cofactor binding
HF553_RS12725	COG0243	molybdopterin cofactor binding
HF553_RS12730	COG0437	4 iron, 4 sulfur cluster binding
HF553_RS12735	COG3302	dmso reductase anchor subunit
HF553_RS12775	COG1940	carbohydrate kinase activity
HF553_RS12780	COG0583	DNA-binding transcription factor activity
HF553_RS12785	COG2814	Major facilitator Superfamily
HF553_RS12795	COG3591	Belongs to the peptidase S1B family
HF553_RS12815	COG0628	permease
HF553_RS12820	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HF553_RS12825	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HF553_RS12835	COG0531	amino acid
HF553_RS12840	COG3136	membrane protein required for alginate biosynthesis
HF553_RS12845	COG0745	RESPONSE REGULATOR receiver
HF553_RS12850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HF553_RS12855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HF553_RS12860	COG2205	protein histidine kinase activity
HF553_RS12885	COG5339	Protein conserved in bacteria
HF553_RS12900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HF553_RS12905	COG0673	inositol 2-dehydrogenase activity
HF553_RS12955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HF553_RS12965	COG0625	glutathione transferase activity
HF553_RS12985	COG3895	Periplasmic Protein
HF553_RS13010	COG1566	PFAM secretion protein HlyD family protein
HF553_RS13025	COG4989	oxidoreductase activity
HF553_RS13030	COG3313	Fe-S protein
HF553_RS13035	COG1309	transcriptional regulator
HF553_RS13040	COG1902	pentaerythritol trinitrate reductase activity
HF553_RS13055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HF553_RS13060	COG0791	NLP P60 protein
HF553_RS13080	COG0583	DNA-binding transcription factor activity
HF553_RS13085	COG2814	Major facilitator Superfamily
HF553_RS13090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HF553_RS13095	COG0307	riboflavin synthase, alpha
HF553_RS13275	COG0789	Transcriptional regulator
HF553_RS13280	COG3272	Protein of unknown function (DUF1722)
HF553_RS13315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HF553_RS13325	COG2267	carboxylic ester hydrolase activity
HF553_RS13330	COG0531	amino acid
HF553_RS13350	COG4238	major outer membrane lipoprotein
HF553_RS13355	COG1376	ErfK ybiS ycfS ynhG family protein
HF553_RS13370	COG0719	Fe-S assembly protein
HF553_RS13375	COG0396	ATPase activity
HF553_RS13380	COG0719	Fe-S assembly protein
HF553_RS13385	COG0316	Belongs to the HesB IscA family
HF553_RS13400	COG2050	protein possibly involved in aromatic compounds catabolism
HF553_RS13405	COG0277	FAD linked oxidase domain protein
HF553_RS13405	COG0247	lactate metabolic process
HF553_RS13425	COG0738	Major facilitator superfamily
HF553_RS13430	COG2271	Major facilitator Superfamily
HF553_RS13445	COG4670	ketone body catabolic process
HF553_RS13450	COG1960	acyl-CoA dehydrogenase activity
HF553_RS13455	COG2207	Transcriptional regulator
HF553_RS13455	COG1917	Cupin 2, conserved barrel domain protein
HF553_RS13460	COG2086	electron transfer activity
HF553_RS13465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HF553_RS13470	COG0644	oxidoreductase
HF553_RS13475	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HF553_RS13480	COG0318	PFAM AMP-dependent synthetase and ligase
HF553_RS13485	COG0574	Belongs to the PEP-utilizing enzyme family
HF553_RS13485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HF553_RS13500	COG4256	Hemin uptake protein
HF553_RS13520	COG0791	NLP P60 protein
HF553_RS13530	COG0386	Belongs to the glutathione peroxidase family
HF553_RS13605	COG3137	Salt-induced outer membrane protein
HF553_RS13610	COG1105	Belongs to the carbohydrate kinase PfkB family
HF553_RS13620	COG3001	Fructosamine kinase
HF553_RS13630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HF553_RS13635	COG1988	membrane-bound metal-dependent
HF553_RS13650	COG0753	catalase activity
HF553_RS13660	COG1486	melibiose metabolic process
HF553_RS13665	COG1917	Cupin 2, conserved barrel domain protein
HF553_RS13665	COG2169	Transcriptional regulator
HF553_RS13670	COG1447	Phosphotransferase system cellobiose-specific component IIA
HF553_RS13675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HF553_RS13680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HF553_RS13685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HF553_RS13700	COG3678	ATP-independent chaperone mediated protein folding
HF553_RS13735	COG0494	nUDIX hydrolase
HF553_RS13750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HF553_RS13760	COG0778	Nitroreductase
HF553_RS13765	COG0616	signal peptide processing
HF553_RS13770	COG0252	asparaginase activity
HF553_RS13775	COG1335	isochorismatase
HF553_RS13780	COG3139	Protein of unknown function (DUF1315)
HF553_RS13800	COG0656	L-ascorbic acid biosynthetic process
HF553_RS13805	COG0641	radical SAM
HF553_RS13810	COG3713	MltA-interacting MipA family protein
HF553_RS13815	COG2766	serine protein kinase
HF553_RS13830	COG2199	diguanylate cyclase activity
HF553_RS13835	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HF553_RS13850	COG2207	Transcriptional regulator
HF553_RS13855	COG2807	transmembrane transport
HF553_RS13860	COG3189	MarR family transcriptional regulator
HF553_RS13870	COG3042	response to heat
HF553_RS13880	COG2261	transglycosylase associated protein
HF553_RS13895	COG3615	Tellurite resistance protein tehB
HF553_RS13905	COG1605	Chorismate mutase
HF553_RS13920	COG0789	Transcriptional regulator
HF553_RS13935	COG3443	Belongs to the bacterial solute-binding protein 9 family
HF553_RS13950	COG0668	transmembrane transport
HF553_RS13955	COG1124	(ABC) transporter
HF553_RS13985	COG3038	cytochrome b561
HF553_RS13995	COG0071	Belongs to the small heat shock protein (HSP20) family
HF553_RS14045	COG3021	interspecies interaction between organisms
HF553_RS14080	COG0538	isocitrate dehydrogenase activity
HF553_RS14095	COG3778	Protein conserved in bacteria
HF553_RS14100	COG3299	homolog of phage Mu protein gp47
HF553_RS14145	COG4386	tail sheath protein
HF553_RS14190	COG4695	Portal protein
HF553_RS14200	COG1802	Transcriptional regulator
HF553_RS14200	COG4626	Terminase
HF553_RS14240	COG0484	heat shock protein binding
HF553_RS14245	COG1403	HNH endonuclease
HF553_RS14255	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HF553_RS14260	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HF553_RS14280	COG3646	Phage regulatory protein
HF553_RS14300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HF553_RS14315	COG5532	Uncharacterized conserved protein (DUF2303)
HF553_RS14320	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HF553_RS14350	COG0582	viral genome integration into host DNA
HF553_RS14355	COG0538	isocitrate dehydrogenase activity
HF553_RS14385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HF553_RS14400	COG2850	peptidyl-arginine hydroxylation
HF553_RS14430	COG1177	transmembrane transport
HF553_RS14450	COG4591	ABC-type transport system involved in lipoprotein release permease component
HF553_RS14455	COG1136	(ABC) transporter
HF553_RS14460	COG4591	ABC-type transport system involved in lipoprotein release permease component
HF553_RS14465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HF553_RS14470	COG1388	LysM domain
HF553_RS14470	COG1376	ErfK ybiS ycfS ynhG family protein
HF553_RS14480	COG1309	transcriptional regulator
HF553_RS14485	COG3134	Outer membrane lipoprotein
HF553_RS14490	COG1252	NADH dehydrogenase
HF553_RS14515	COG5633	Lipoprotein
HF553_RS14520	COG0537	adenosine 5'-monophosphoramidase activity
HF553_RS14525	COG4773	Receptor
HF553_RS14535	COG0084	hydrolase, TatD family'
HF553_RS14540	COG0470	DNA polymerase III
HF553_RS14550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HF553_RS14555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HF553_RS14560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HF553_RS14580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HF553_RS14605	COG0564	pseudouridine synthase activity
HF553_RS14610	COG1530	ribonuclease E activity
HF553_RS14700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HF553_RS14710	COG2999	glutathione oxidoreductase activity
HF553_RS14745	COG3038	cytochrome b561
HF553_RS14760	COG1560	Kdo2-lipid A biosynthetic process
HF553_RS14775	COG5645	(Lipo)protein
HF553_RS14780	COG2943	transferase activity, transferring hexosyl groups
HF553_RS14795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HF553_RS14855	COG3381	protein complex oligomerization
HF553_RS14930	COG0673	inositol 2-dehydrogenase activity
HF553_RS14935	COG2814	Major facilitator Superfamily
HF553_RS14955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HF553_RS14960	COG1737	Transcriptional regulator
HF553_RS14965	COG1702	phosphate starvation-inducible protein PhoH
HF553_RS14985	COG1309	transcriptional regulator
HF553_RS14990	COG3729	General stress protein
HF553_RS15010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HF553_RS15015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HF553_RS15015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HF553_RS15020	COG4232	protein-disulfide reductase activity
HF553_RS15065	COG3971	2-oxopent-4-enoate hydratase activity
HF553_RS15075	COG3384	dioxygenase
HF553_RS15080	COG1012	belongs to the aldehyde dehydrogenase family
HF553_RS15090	COG1846	Transcriptional regulator
HF553_RS15095	COG2368	4-hydroxyphenylacetate
HF553_RS15110	COG0745	RESPONSE REGULATOR receiver
HF553_RS15115	COG2205	protein histidine kinase activity
HF553_RS15165	COG0670	Belongs to the BI1 family
HF553_RS15185	COG1881	PFAM PEBP family protein
HF553_RS15200	COG1832	CoA-binding protein
HF553_RS15215	COG0210	DNA helicase
HF553_RS15220	COG3304	Inner membrane component domain
HF553_RS15225	COG1289	transmembrane transporter activity
HF553_RS15230	COG3070	regulator of competence-specific genes
HF553_RS15250	COG1067	ATP-dependent peptidase activity
HF553_RS15260	COG3130	regulation of translation
HF553_RS15265	COG3009	Protein conserved in bacteria
HF553_RS15270	COG3008	intermembrane lipid transfer
HF553_RS15270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HF553_RS15275	COG2995	paraquat-inducible protein a
HF553_RS15280	COG0488	(ABC) transporter
HF553_RS15290	COG0633	Ferredoxin
HF553_RS15290	COG3217	Mosc domain protein beta barrel domain protein
HF553_RS15305	COG0308	aminopeptidase N
HF553_RS15315	COG0017	Asparaginyl-tRNA synthetase
HF553_RS15320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HF553_RS15325	COG1448	Aminotransferase
HF553_RS15330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HF553_RS15335	COG3108	Peptidase M15
HF553_RS15340	COG2989	Protein conserved in bacteria
HF553_RS15350	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HF553_RS15360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HF553_RS15365	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HF553_RS15370	COG3173	Aminoglycoside phosphotransferase
HF553_RS15385	COG3214	Protein conserved in bacteria
HF553_RS15400	COG0658	competence protein
HF553_RS15400	COG2333	competence protein COMEC
HF553_RS15410	COG0539	negative regulation of cytoplasmic translation
HF553_RS15420	COG0501	Belongs to the peptidase M48B family
HF553_RS15435	COG2323	membrane
HF553_RS15440	COG1944	ATP diphosphatase activity
HF553_RS15445	COG2116	formate transmembrane transporter activity
HF553_RS15450	COG1882	Formate acetyltransferase
HF553_RS15465	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HF553_RS15470	COG0531	amino acid
HF553_RS15480	COG3302	dmso reductase anchor subunit
HF553_RS15485	COG0437	4 iron, 4 sulfur cluster binding
HF553_RS15490	COG0243	molybdopterin cofactor binding
HF553_RS15500	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HF553_RS15520	COG0492	ferredoxin-NADP+ reductase activity
HF553_RS15525	COG4988	ABC transporter
HF553_RS15530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HF553_RS15550	COG0583	DNA-binding transcription factor activity
HF553_RS15560	COG1335	isochorismatase
HF553_RS15580	COG0542	response to heat
HF553_RS15590	COG1278	Cold shock
HF553_RS15595	COG0577	efflux transmembrane transporter activity
HF553_RS15595	COG1136	(ABC) transporter
HF553_RS15600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HF553_RS15605	COG2990	Protein conserved in bacteria
HF553_RS15610	COG3593	DNA synthesis involved in DNA repair
HF553_RS15615	COG2431	L-lysine efflux transmembrane transporter activity
HF553_RS15625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HF553_RS15630	COG0028	Belongs to the TPP enzyme family
HF553_RS15635	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HF553_RS15640	COG0702	epimerase
HF553_RS15645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HF553_RS15650	COG3023	N-Acetylmuramoyl-L-alanine amidase
HF553_RS15665	COG1126	abc transporter atp-binding protein
HF553_RS15670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HF553_RS15675	COG4215	(ABC) transporter
HF553_RS15680	COG4160	amino acid transport
HF553_RS15685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HF553_RS15715	COG1177	transmembrane transport
HF553_RS15720	COG1176	ABC-type spermidine putrescine transport system, permease component I
HF553_RS15725	COG3842	ATPase activity
HF553_RS15730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HF553_RS15770	COG3226	Transcriptional regulator
HF553_RS15775	COG0738	Major facilitator superfamily
HF553_RS15780	COG0561	phosphatase activity
HF553_RS15785	COG2814	Major facilitator Superfamily
HF553_RS15790	COG0671	phosphoesterase, PA-phosphatase related
HF553_RS15795	COG1349	DNA-binding transcription factor activity
HF553_RS15800	COG1686	Belongs to the peptidase S11 family
HF553_RS15805	COG0625	glutathione transferase activity
HF553_RS15810	COG2133	pyrroloquinoline quinone binding
HF553_RS15835	COG0747	negative chemotaxis
HF553_RS15860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HF553_RS15865	COG1882	Formate acetyltransferase
HF553_RS15870	COG0561	phosphatase activity
HF553_RS15880	COG0488	(ABC) transporter
HF553_RS15885	COG1376	ErfK ybiS ycfS ynhG family protein
HF553_RS15890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HF553_RS15905	COG2194	sulfuric ester hydrolase activity
HF553_RS15910	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HF553_RS15925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HF553_RS15930	COG0765	amino acid transport
HF553_RS15935	COG1126	abc transporter atp-binding protein
HF553_RS15940	COG0668	transmembrane transport
HF553_RS15950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HF553_RS15960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HF553_RS15970	COG0513	Belongs to the DEAD box helicase family
HF553_RS15975	COG1309	transcriptional regulator
HF553_RS15980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HF553_RS15985	COG1131	(ABC) transporter
HF553_RS15990	COG0842	Transport permease protein
HF553_RS15995	COG0842	Transport permease protein
HF553_RS16005	COG3568	Endonuclease Exonuclease Phosphatase
HF553_RS16010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HF553_RS16015	COG0392	lysyltransferase activity
HF553_RS16030	COG0670	Belongs to the BI1 family
HF553_RS16040	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HF553_RS16050	COG0521	Mo-molybdopterin cofactor biosynthetic process
HF553_RS16075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HF553_RS16100	COG1881	PFAM PEBP family protein
HF553_RS16130	COG4677	pectinesterase activity
HF553_RS16140	COG0561	phosphatase activity
HF553_RS16150	COG4149	molybdate abc transporter
HF553_RS16155	COG0725	ABC transporter, periplasmic molybdate-binding protein
HF553_RS16165	COG3585	molybdate ion transport
HF553_RS16165	COG2005	Transcriptional regulator
HF553_RS16170	COG1119	ATPase activity
HF553_RS16195	COG2017	converts alpha-aldose to the beta-anomer
HF553_RS16205	COG1120	ATPase activity
HF553_RS16210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HF553_RS16220	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HF553_RS16225	COG5016	pyruvate
HF553_RS16225	COG0511	ligase activity, forming carbon-carbon bonds
HF553_RS16235	COG0471	metal ion transport
HF553_RS16235	COG0490	domain, Protein
HF553_RS16240	COG0583	DNA-binding transcription factor activity
HF553_RS16245	COG0583	DNA-binding transcription factor activity
HF553_RS16255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HF553_RS16255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HF553_RS16260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HF553_RS16270	COG1230	cation diffusion facilitator family transporter
HF553_RS16315	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HF553_RS16320	COG2885	chlorophyll binding
HF553_RS16330	COG3064	Membrane
HF553_RS16335	COG0848	biopolymer transport protein
HF553_RS16340	COG0811	peptide transport
HF553_RS16345	COG0824	Thioesterase
HF553_RS16350	COG3790	cyd operon protein YbgE
HF553_RS16355	COG4890	Cyd operon protein YbgT
HF553_RS16360	COG1294	oxidase, subunit
HF553_RS16365	COG1271	oxidase subunit
HF553_RS16370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HF553_RS16380	COG0508	dehydrogenase complex catalyzes the overall conversion of
HF553_RS16385	COG0567	Dehydrogenase, E1 component
HF553_RS16400	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HF553_RS16420	COG3180	Ammonia monooxygenase
HF553_RS16435	COG1984	allophanate hydrolase subunit 2
HF553_RS16440	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HF553_RS16485	COG2205	protein histidine kinase activity
HF553_RS16490	COG0745	RESPONSE REGULATOR receiver
HF553_RS16505	COG1982	Orn Lys Arg decarboxylase major
HF553_RS16510	COG0531	amino acid
HF553_RS16520	COG0033	Phosphoglucomutase
HF553_RS16530	COG0596	Alpha beta hydrolase
HF553_RS16545	COG0735	belongs to the Fur family
HF553_RS16550	COG0583	DNA-binding transcription factor activity
HF553_RS16555	COG1053	succinate dehydrogenase
HF553_RS16595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HF553_RS16600	COG1846	Transcriptional regulator
HF553_RS16600	COG1940	carbohydrate kinase activity
HF553_RS16605	COG0647	UMP catabolic process
HF553_RS16610	COG0367	asparagine synthase
HF553_RS16645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HF553_RS16655	COG1702	phosphate starvation-inducible protein PhoH
HF553_RS16680	COG0765	amino acid transport
HF553_RS16685	COG0765	amino acid transport
HF553_RS16690	COG1126	abc transporter atp-binding protein
HF553_RS16705	COG2888	peptidyl-tyrosine sulfation
HF553_RS16710	COG3290	protein histidine kinase activity
HF553_RS16710	COG3829	transcription factor binding
HF553_RS16740	COG1466	dna polymerase III delta subunit
HF553_RS16750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HF553_RS16760	COG0799	negative regulation of ribosome biogenesis
HF553_RS16770	COG0768	penicillin binding
HF553_RS16775	COG0772	Belongs to the SEDS family
HF553_RS16780	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HF553_RS16785	COG1686	Belongs to the peptidase S11 family
HF553_RS16800	COG0583	DNA-binding transcription factor activity
HF553_RS16815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HF553_RS16835	COG3069	C4-dicarboxylate transmembrane transporter activity
HF553_RS16840	COG4565	transcriptional regulatory protein
HF553_RS16845	COG3290	protein histidine kinase activity
HF553_RS16850	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HF553_RS16860	COG2301	Belongs to the HpcH HpaI aldolase family
HF553_RS16865	COG3051	citrate lyase alpha subunit
HF553_RS16880	COG0471	metal ion transport
HF553_RS16885	COG3719	Belongs to the RNase T2 family
HF553_RS16890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HF553_RS16895	COG1063	alcohol dehydrogenase
HF553_RS16915	COG0243	molybdopterin cofactor binding
HF553_RS16935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HF553_RS16940	COG0583	DNA-binding transcription factor activity
HF553_RS16945	COG3969	phosphoadenosine phosphosulfate
HF553_RS16950	COG1475	DNA binding
HF553_RS16955	COG0436	Aminotransferase
HF553_RS16960	COG0371	Dehydrogenase
HF553_RS16965	COG2879	small protein
HF553_RS16970	COG1966	Carbon starvation protein
HF553_RS16980	COG1028	Short-chain dehydrogenase reductase Sdr
HF553_RS16985	COG1535	isochorismatase
HF553_RS16985	COG3433	isochorismatase activity
HF553_RS16990	COG1021	2,3-dihydroxybenzoate-AMP ligase
HF553_RS16995	COG1169	isochorismate synthase
HF553_RS17000	COG4592	Periplasmic binding protein
HF553_RS17010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HF553_RS17015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HF553_RS17020	COG1120	ATPase activity
HF553_RS17025	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HF553_RS17030	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HF553_RS17030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HF553_RS17035	COG3251	PFAM MbtH domain protein
HF553_RS17040	COG2382	esterase
HF553_RS17045	COG4771	TonB-dependent receptor
HF553_RS17050	COG2977	Belongs to the P-Pant transferase superfamily
HF553_RS17075	COG2315	Protein conserved in bacteria
HF553_RS17090	COG0668	transmembrane transport
HF553_RS17095	COG1113	amino acid transport
HF553_RS17105	COG3059	membrane
HF553_RS17115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HF553_RS17120	COG2207	Transcriptional regulator
HF553_RS17140	COG2246	polysaccharide biosynthetic process
HF553_RS17145	COG0463	Glycosyl transferase, family 2
HF553_RS17225	COG2501	S4 domain
HF553_RS17230	COG1988	membrane-bound metal-dependent
HF553_RS17250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HF553_RS17260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HF553_RS17265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HF553_RS17270	COG0549	Belongs to the carbamate kinase family
HF553_RS17280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HF553_RS17285	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HF553_RS17290	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HF553_RS17295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HF553_RS17300	COG3257	ureidoglycine aminohydrolase activity
HF553_RS17305	COG1929	Belongs to the glycerate kinase type-1 family
HF553_RS17310	COG2233	PERMEase
HF553_RS17320	COG1953	Uracil, thiamine, allantoin
HF553_RS17330	COG2084	Dehydrogenase
HF553_RS17335	COG3622	Belongs to the hyi family
HF553_RS17340	COG3960	tartronate-semialdehyde synthase activity
HF553_RS17375	COG1464	Belongs to the NlpA lipoprotein family
HF553_RS17385	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HF553_RS17390	COG4181	ATPase activity
HF553_RS17395	COG2755	lipolytic protein G-D-S-L family
HF553_RS17400	COG0300	oxidoreductase activity
HF553_RS17405	COG3118	belongs to the thioredoxin family
HF553_RS17410	COG0390	transport system, permease component
HF553_RS17415	COG4619	ABC transporter
HF553_RS17420	COG0330	HflC and HflK could
HF553_RS17425	COG1585	Membrane protein implicated in regulation of membrane protease activity
HF553_RS17435	COG2217	Heavy metal translocating P-type atpase
HF553_RS17445	COG3735	TraB family
HF553_RS17460	COG2223	nitrite transmembrane transporter activity
HF553_RS17465	COG4651	solute:proton antiporter activity
HF553_RS17465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HF553_RS17470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HF553_RS17515	COG2832	Protein of unknown function (DUF454)
HF553_RS17520	COG3923	Primosomal replication protein n
HF553_RS17530	COG5464	transposase or invertase
HF553_RS17535	COG1196	nuclear chromosome segregation
HF553_RS17535	COG3264	Mechanosensitive ion channel
HF553_RS17540	COG1309	transcriptional regulator
HF553_RS17545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HF553_RS17550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HF553_RS17565	COG0110	maltose O-acetyltransferase activity
HF553_RS17585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HF553_RS17595	COG3695	enzyme binding
HF553_RS17600	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HF553_RS17605	COG1946	Acyl-CoA thioesterase
HF553_RS17610	COG0004	ammonium transporteR
HF553_RS17615	COG0347	Belongs to the P(II) protein family
HF553_RS17620	COG1132	(ABC) transporter
HF553_RS17625	COG1132	(ABC) transporter
HF553_RS17630	COG1522	sequence-specific DNA binding
HF553_RS17645	COG4533	DNA binding
HF553_RS17655	COG0824	Thioesterase
HF553_RS17660	COG1555	photosystem II stabilization
HF553_RS17665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HF553_RS17675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HF553_RS17695	COG0271	Belongs to the BolA IbaG family
HF553_RS17700	COG3056	Lipoprotein
HF553_RS17705	COG2223	nitrite transmembrane transporter activity
HF553_RS17710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HF553_RS17715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HF553_RS17720	COG1845	cytochrome c oxidase, subunit III
HF553_RS17725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HF553_RS17750	COG2814	Major facilitator Superfamily
HF553_RS17780	COG2188	Transcriptional regulator
HF553_RS17815	COG0142	geranyltranstransferase activity
HF553_RS17825	COG0667	Aldo Keto reductase
HF553_RS17830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HF553_RS17850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HF553_RS17850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HF553_RS17860	COG4238	major outer membrane lipoprotein
HF553_RS17890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HF553_RS17900	COG1862	Preprotein translocase
HF553_RS17920	COG0450	alkyl hydroperoxide reductase
HF553_RS17930	COG0366	Alpha amylase catalytic
HF553_RS17945	COG5002	protein histidine kinase activity
HF553_RS17955	COG0420	3'-5' exonuclease activity
HF553_RS17960	COG0419	ATPase involved in DNA repair
HF553_RS17965	COG2814	Major facilitator Superfamily
HF553_RS17970	COG1940	carbohydrate kinase activity
HF553_RS17985	COG4126	flavin adenine dinucleotide binding
HF553_RS18005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HF553_RS18010	COG3706	GGDEF domain
HF553_RS18055	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HF553_RS18060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HF553_RS18075	COG0113	porphobilinogen synthase activity
HF553_RS18110	COG1280	lysine exporter protein (LysE YggA)
HF553_RS18130	COG1294	oxidase, subunit
HF553_RS18135	COG1271	oxidase subunit
HF553_RS18165	COG2814	Major facilitator Superfamily
HF553_RS18175	COG0789	Transcriptional regulator
HF553_RS18230	COG2200	EAL domain
HF553_RS18245	COG3539	Fimbrial protein
HF553_RS18250	COG3121	Chaperone
HF553_RS18255	COG3188	usher protein
HF553_RS18310	COG2003	Belongs to the UPF0758 family
HF553_RS18325	COG3468	outer membrane autotransporter barrel domain protein
HF553_RS18440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HF553_RS18450	COG3039	Transposase
HF553_RS18465	COG4983	Phage plasmid primase, P4 family domain protein
HF553_RS18470	COG4983	Phage plasmid primase, P4 family domain protein
HF553_RS18525	COG2195	Cleaves the N-terminal amino acid of tripeptides
HF553_RS18530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HF553_RS18535	COG1690	Belongs to the RtcB family
HF553_RS18545	COG3034	peptidoglycan biosynthetic process
HF553_RS18550	COG0121	glutamine amidotransferase
HF553_RS18570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HF553_RS18595	COG1522	sequence-specific DNA binding
HF553_RS18720	COG3501	Rhs element vgr protein
HF553_RS18765	COG3047	cAMP biosynthetic process
HF553_RS18765	COG2885	chlorophyll binding
HF553_RS18855	COG2226	methyltransferase
HF553_RS18865	COG1388	LysM domain
HF553_RS18865	COG0741	lytic transglycosylase activity
HF553_RS18870	COG2226	methyltransferase
HF553_RS18880	COG2814	Major facilitator Superfamily
HF553_RS18885	COG0583	DNA-binding transcription factor activity
HF553_RS18890	COG0656	L-ascorbic acid biosynthetic process
HF553_RS18925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HF553_RS18950	COG1720	tRNA m6t6A37 methyltransferase activity
HF553_RS18960	COG3015	lipoprotein NlpE involved in copper resistance
HF553_RS18965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HF553_RS18980	COG4568	rho-dependent transcription termination
HF553_RS18990	COG0346	lactoylglutathione lyase activity
HF553_RS19055	COG0575	Belongs to the CDS family
HF553_RS19105	COG0477	Major facilitator Superfamily
HF553_RS19115	COG3835	regulator
HF553_RS19135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HF553_RS19140	COG2860	membrane
HF553_RS19170	COG3539	Fimbrial protein
HF553_RS19175	COG3539	Fimbrial protein
HF553_RS19180	COG3121	Chaperone
HF553_RS19185	COG3188	usher protein
HF553_RS19200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HF553_RS19205	COG1120	ATPase activity
HF553_RS19210	COG4774	siderophore transport
HF553_RS19215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HF553_RS19220	COG1643	Atp-dependent helicase
HF553_RS19225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HF553_RS19250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HF553_RS19275	COG3121	Chaperone
HF553_RS19280	COG3188	usher protein
HF553_RS19285	COG3539	Fimbrial protein
HF553_RS19305	COG0726	polysaccharide deacetylase
HF553_RS19310	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS19315	COG0842	Transport permease protein
HF553_RS19320	COG1131	(ABC) transporter
HF553_RS19325	COG0288	reversible hydration of carbon dioxide
HF553_RS19335	COG4993	Dehydrogenase
HF553_RS19340	COG2132	Multicopper oxidase
HF553_RS19360	COG1349	DNA-binding transcription factor activity
HF553_RS19390	COG3064	Membrane
HF553_RS19405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HF553_RS19410	COG0508	dehydrogenase complex catalyzes the overall conversion of
HF553_RS19415	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HF553_RS19430	COG2211	Major facilitator Superfamily
HF553_RS19435	COG3940	Belongs to the glycosyl hydrolase 43 family
HF553_RS19440	COG3725	Membrane protein required for beta-lactamase induction
HF553_RS19455	COG4969	Belongs to the N-Me-Phe pilin family
HF553_RS19460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HF553_RS19465	COG1459	type II secretion system
HF553_RS19500	COG0494	nUDIX hydrolase
HF553_RS19520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HF553_RS19525	COG0849	cell division
HF553_RS19550	COG0772	Belongs to the SEDS family
HF553_RS19565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HF553_RS19575	COG0768	penicillin binding
HF553_RS19670	COG0586	Pfam SNARE associated Golgi protein
HF553_RS19710	COG0417	DNA replication proofreading
HF553_RS19730	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HF553_RS19740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HF553_RS19775	COG3119	arylsulfatase activity
HF553_RS19795	COG2271	Major facilitator Superfamily
HF553_RS19805	COG0644	oxidoreductase
HF553_RS19915	COG5016	pyruvate
HF553_RS19915	COG0511	ligase activity, forming carbon-carbon bonds
HF553_RS19920	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HF553_RS19950	COG1047	Peptidyl-prolyl cis-trans
HF553_RS19965	COG0196	riboflavin kinase activity
HF553_RS19990	COG0583	DNA-binding transcription factor activity
HF553_RS20010	COG0641	radical SAM
HF553_RS20015	COG3119	arylsulfatase activity
HF553_RS20025	COG0737	Belongs to the 5'-nucleotidase family
HF553_RS20060	COG3121	Chaperone
HF553_RS20065	COG3539	Fimbrial protein
HF553_RS20080	COG3188	usher protein
HF553_RS20145	COG4735	regulation of single-species biofilm formation
HF553_RS20150	COG1584	GPR1 FUN34 yaaH family protein
HF553_RS20155	COG0521	Mo-molybdopterin cofactor biosynthetic process
HF553_RS20165	COG1115	amino acid carrier protein
HF553_RS20175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HF553_RS20185	COG0527	aspartate kinase activity
HF553_RS20185	COG0460	homoserine dehydrogenase
HF553_RS20195	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HF553_RS20205	COG0745	RESPONSE REGULATOR receiver
HF553_RS20225	COG3121	Chaperone
HF553_RS20245	COG4452	Inner membrane protein CreD
HF553_RS20250	COG2205	protein histidine kinase activity
HF553_RS20255	COG0745	RESPONSE REGULATOR receiver
HF553_RS20260	COG3045	CreA protein
HF553_RS20265	COG3708	Transcriptional regulator
HF553_RS20265	COG2207	Transcriptional regulator
HF553_RS20290	COG0488	(ABC) transporter
HF553_RS20305	COG0560	Phosphoserine phosphatase
HF553_RS20310	COG3726	membrane protein affecting hemolysin expression
HF553_RS20345	COG1328	CTP reductase activity
HF553_RS20350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HF553_RS20355	COG0084	hydrolase, TatD family'
HF553_RS20360	COG4667	esterase of the alpha-beta hydrolase superfamily
HF553_RS20370	COG2823	Periplasmic or secreted lipoprotein
HF553_RS20380	COG1011	Hydrolase
HF553_RS20390	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HF553_RS20420	COG3706	GGDEF domain
HF553_RS20425	COG4114	ferric iron reductase
HF553_RS20430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HF553_RS20435	COG2197	response regulator
HF553_RS20440	COG2197	response regulator
HF553_RS20445	COG2966	Psort location CytoplasmicMembrane, score
HF553_RS20460	COG1484	DNA-dependent DNA replication
HF553_RS20475	COG0840	transmembrane signaling receptor activity
HF553_RS20480	COG1966	Carbon starvation protein
HF553_RS20485	COG2879	small protein
HF553_RS20490	COG0523	cobalamin synthesis protein
HF553_RS20500	COG1280	lysine exporter protein (LysE YggA)
HF553_RS20505	COG3586	endonuclease activity
HF553_RS20520	COG1012	belongs to the aldehyde dehydrogenase family
HF553_RS20525	COG5464	transposase or invertase
HF553_RS20535	COG2733	membrane
HF553_RS20540	COG0477	Major facilitator Superfamily
HF553_RS20545	COG3366	ferrous iron transmembrane transporter activity
HF553_RS20550	COG0700	Nucleoside recognition
HF553_RS20555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HF553_RS20560	COG0583	DNA-binding transcription factor activity
HF553_RS20580	COG2186	Transcriptional regulator
HF553_RS20585	COG0412	Dienelactone hydrolase
HF553_RS20610	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HF553_RS20680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HF553_RS20685	COG0464	growth
HF553_RS20690	COG1404	Belongs to the peptidase S8 family
HF553_RS20695	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HF553_RS20705	COG0582	viral genome integration into host DNA
HF553_RS20715	COG1064	alcohol dehydrogenase
HF553_RS20720	COG3265	gluconokinase activity
HF553_RS20725	COG1063	alcohol dehydrogenase
HF553_RS20730	COG1028	Short-chain dehydrogenase reductase Sdr
HF553_RS20735	COG2610	gluconate transmembrane transporter activity
HF553_RS20740	COG1609	Transcriptional regulator
HF553_RS20745	COG0795	lipopolysaccharide-transporting ATPase activity
HF553_RS20750	COG0795	lipopolysaccharide-transporting ATPase activity
HF553_RS20760	COG2927	DNA polymerase III (CHI subunit)
HF553_RS20800	COG2731	YhcH YjgK YiaL family protein
HF553_RS20820	COG1288	antiporter activity
HF553_RS20825	COG1438	arginine binding
HF553_RS20870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HF553_RS20870	COG1263	PTS System
HF553_RS20875	COG0366	Alpha amylase catalytic
HF553_RS20890	COG2026	Addiction module toxin, RelE StbE family
HF553_RS20895	COG3077	Addiction module antitoxin, RelB DinJ family
HF553_RS20900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HF553_RS20900	COG3711	transcriptional antiterminator
HF553_RS20915	COG3964	amidohydrolase
HF553_RS20950	COG0312	modulator of DNA gyrase
HF553_RS20960	COG1082	Xylose isomerase domain protein TIM barrel
HF553_RS20970	COG2814	Major facilitator Superfamily
HF553_RS20975	COG0673	inositol 2-dehydrogenase activity
HF553_RS20980	COG3962	Belongs to the TPP enzyme family
HF553_RS20985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HF553_RS20995	COG1082	Xylose isomerase domain protein TIM barrel
HF553_RS21000	COG5520	Belongs to the glycosyl hydrolase 30 family
HF553_RS21030	COG3718	enzyme involved in inositol metabolism
HF553_RS21035	COG2814	Major facilitator Superfamily
HF553_RS21035	COG0477	Major facilitator Superfamily
HF553_RS21040	COG0477	Major facilitator Superfamily
HF553_RS21040	COG2814	Major facilitator Superfamily
HF553_RS21045	COG0837	glucose binding
HF553_RS21045	COG1737	Transcriptional regulator
HF553_RS21050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HF553_RS21065	COG3964	amidohydrolase
HF553_RS21070	COG2271	Major facilitator Superfamily
HF553_RS21075	COG2105	PFAM AIG2 family protein
HF553_RS21095	COG1253	flavin adenine dinucleotide binding
HF553_RS21105	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HF553_RS21120	COG1733	regulation of RNA biosynthetic process
HF553_RS21125	COG0702	epimerase
HF553_RS21130	COG0697	spore germination
HF553_RS21140	COG1113	amino acid transport
HF553_RS21145	COG0545	Peptidyl-prolyl cis-trans isomerase
HF553_RS21150	COG3061	Opacity-associated protein A
HF553_RS21165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HF553_RS21230	COG1073	alpha beta
HF553_RS21235	COG3650	response to hydrogen peroxide
HF553_RS21245	COG1960	acyl-CoA dehydrogenase activity
HF553_RS21250	COG0754	glutathionylspermidine amidase activity
HF553_RS21255	COG5463	Belongs to the UPF0441 family
HF553_RS21260	COG3766	membrane
HF553_RS21270	COG1842	Phage shock protein A
HF553_RS21275	COG3789	protein conserved in bacteria
HF553_RS21285	COG0557	exoribonuclease II activity
HF553_RS21300	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HF553_RS21305	COG0330	HflC and HflK could
HF553_RS21310	COG0330	HflC and HflK could
HF553_RS21315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HF553_RS21340	COG0802	atpase or kinase
HF553_RS21345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HF553_RS21345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HF553_RS21370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HF553_RS21390	COG1511	domain protein
HF553_RS21390	COG3264	Mechanosensitive ion channel
HF553_RS21410	COG1053	succinate dehydrogenase
HF553_RS21415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HF553_RS21445	COG5510	response to toxic substance
HF553_RS21485	COG0531	amino acid
HF553_RS21490	COG3030	protein affecting phage T7 exclusion by the F plasmid
HF553_RS21495	COG1027	Aspartate ammonia-lyase
HF553_RS21500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HF553_RS21515	COG1309	transcriptional regulator
HF553_RS21525	COG0582	viral genome integration into host DNA
HF553_RS21530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HF553_RS21530	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HF553_RS21535	COG2194	sulfuric ester hydrolase activity
HF553_RS21650	COG3596	GTP binding
HF553_RS21655	COG2378	regulation of single-species biofilm formation
HF553_RS21685	COG2003	Belongs to the UPF0758 family
HF553_RS21735	COG0671	phosphoesterase, PA-phosphatase related
HF553_RS21765	COG2197	response regulator
HF553_RS21790	COG3381	protein complex oligomerization
HF553_RS21795	COG3302	dmso reductase anchor subunit
HF553_RS21800	COG0437	4 iron, 4 sulfur cluster binding
HF553_RS21805	COG0243	molybdopterin cofactor binding
HF553_RS21810	COG3290	protein histidine kinase activity
HF553_RS21815	COG4565	transcriptional regulatory protein
HF553_RS21825	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HF553_RS21830	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HF553_RS21830	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HF553_RS21845	COG2169	Transcriptional regulator
HF553_RS21850	COG1982	Orn Lys Arg decarboxylase major
HF553_RS21855	COG2207	Transcriptional regulator
HF553_RS21860	COG0531	amino acid
HF553_RS21890	COG2824	Alkylphosphonate utilization operon protein PhnA
HF553_RS21895	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HF553_RS21915	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HF553_RS21925	COG1301	dicarboxylic acid transport
HF553_RS21930	COG4235	cytochrome complex assembly
HF553_RS21935	COG3088	subunit of a heme lyase
HF553_RS21940	COG1138	Cytochrome C-type biogenesis protein
HF553_RS21945	COG3301	Polysulphide reductase, NrfD
HF553_RS21950	COG0437	4 iron, 4 sulfur cluster binding
HF553_RS21955	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HF553_RS21965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HF553_RS21970	COG3162	membrane
HF553_RS21980	COG1346	cytolysis
HF553_RS21985	COG1380	Effector of murein hydrolase LrgA
HF553_RS21990	COG0583	DNA-binding transcription factor activity
HF553_RS21995	COG0025	NhaP-type Na H and K H
HF553_RS22000	COG2252	PERMEase
HF553_RS22020	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HF553_RS22080	COG2315	Protein conserved in bacteria
HF553_RS22090	COG3700	Belongs to the class B bacterial acid phosphatase family
HF553_RS22130	COG0735	belongs to the Fur family
HF553_RS22145	COG0534	Mate efflux family protein
HF553_RS22155	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HF553_RS22200	COG3833	ABC-type maltose transport systems, permease component
HF553_RS22210	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HF553_RS22235	COG0527	aspartate kinase activity
HF553_RS22250	COG0561	phosphatase activity
HF553_RS22255	COG1349	DNA-binding transcription factor activity
HF553_RS22270	COG3122	Protein conserved in bacteria
HF553_RS22315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HF553_RS22355	COG0151	Belongs to the GarS family
HF553_RS22360	COG2204	response regulator
HF553_RS22420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HF553_RS22425	COG2104	thiamine diphosphate biosynthetic process
HF553_RS22485	COG0250	Participates in transcription elongation, termination and antitermination
HF553_RS22535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HF553_RS22595	COG0583	DNA-binding transcription factor activity
HF553_RS22635	COG2207	Transcriptional regulator
HF553_RS22645	COG0371	Dehydrogenase
HF553_RS22650	COG3738	Protein conserved in bacteria
HF553_RS22670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HF553_RS22675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HF553_RS22680	COG0737	Belongs to the 5'-nucleotidase family
HF553_RS22695	COG0668	transmembrane transport
HF553_RS22700	COG0460	homoserine dehydrogenase
HF553_RS22700	COG0527	aspartate kinase activity
HF553_RS22705	COG0626	cystathionine gamma-synthase activity
HF553_RS22730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HF553_RS22735	COG1609	Transcriptional regulator
HF553_RS22740	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HF553_RS22755	COG1575	Belongs to the MenA family. Type 1 subfamily
HF553_RS22770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HF553_RS22780	COG1494	fructose-1,6-bisphosphatase
HF553_RS22790	COG3152	Membrane
HF553_RS22810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HF553_RS22825	COG2211	Major facilitator Superfamily
HF553_RS22850	COG3678	ATP-independent chaperone mediated protein folding
HF553_RS22855	COG0745	RESPONSE REGULATOR receiver
HF553_RS22860	COG2205	protein histidine kinase activity
HF553_RS22870	COG2258	MOSC domain
HF553_RS22885	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HF553_RS22930	COG1454	alcohol dehydrogenase
HF553_RS22945	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HF553_RS22975	COG0437	4 iron, 4 sulfur cluster binding
HF553_RS22980	COG2864	formate dehydrogenase
HF553_RS22995	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HF553_RS23005	COG4680	protein conserved in bacteria
HF553_RS23010	COG5499	transcription regulator containing HTH domain
HF553_RS23015	COG0456	acetyltransferase
HF553_RS23030	COG1011	Hydrolase
HF553_RS23035	COG1349	DNA-binding transcription factor activity
HF553_RS23040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HF553_RS23050	COG3684	Belongs to the aldolase LacD family
HF553_RS23060	COG2017	converts alpha-aldose to the beta-anomer
HF553_RS23065	COG1501	Belongs to the glycosyl hydrolase 31 family
HF553_RS23110	COG0561	phosphatase activity
HF553_RS23165	COG0204	Acyl-transferase
HF553_RS23180	COG3084	Protein conserved in bacteria
HF553_RS23190	COG1763	Mo-molybdopterin cofactor biosynthetic process
HF553_RS23235	COG1739	Uncharacterized protein family UPF0029
HF553_RS23265	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HF553_RS23280	COG0805	protein transport
HF553_RS23285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HF553_RS23325	COG0641	radical SAM
HF553_RS23345	COG0561	phosphatase activity
HF553_RS23350	COG2267	carboxylic ester hydrolase activity
HF553_RS23355	COG1280	lysine exporter protein (LysE YggA)
HF553_RS23360	COG1280	lysine exporter protein (LysE YggA)
HF553_RS23405	COG1011	Hydrolase
HF553_RS23410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HF553_RS23465	COG2959	enzyme of heme biosynthesis
HF553_RS23470	COG3071	HemY protein
HF553_RS23520	COG2244	polysaccharide biosynthetic process
HF553_RS23525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HF553_RS23530	COG0456	acetyltransferase
HF553_RS23535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HF553_RS23535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HF553_RS23540	COG1088	dTDP-glucose 4,6-dehydratase activity
HF553_RS23545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HF553_RS23575	COG3118	belongs to the thioredoxin family
HF553_RS23645	COG3978	acetolactate synthase activity
HF553_RS23705	COG2186	Transcriptional regulator
HF553_RS23710	COG0477	Major facilitator Superfamily
HF553_RS23715	COG1609	Transcriptional regulator
HF553_RS23720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HF553_RS23730	COG1172	Belongs to the binding-protein-dependent transport system permease family
HF553_RS23765	COG1522	sequence-specific DNA binding
HF553_RS23770	COG0716	FMN binding
HF553_RS23785	COG3312	ion transport
HF553_RS23920	COG4533	DNA binding
HF553_RS23925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HF553_RS23930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HF553_RS23930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HF553_RS23930	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HF553_RS23935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HF553_RS23940	COG0573	inorganic phosphate transmembrane transporter activity
HF553_RS23945	COG0581	inorganic phosphate transmembrane transporter activity
HF553_RS23955	COG0704	Plays a role in the regulation of phosphate uptake
HF553_RS23960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HF553_RS23965	COG2252	PERMEase
HF553_RS23970	COG0431	NADPH-dependent FMN reductase
HF553_RS23975	COG2091	lysine biosynthetic process via aminoadipic acid