locus-tag	class	description
FA582_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FA582_RS00010	COG0592	DNA-directed DNA polymerase activity
FA582_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FA582_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FA582_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FA582_RS00030	COG0187	DNA topoisomerase II activity
FA582_RS00120	COG3655	Transcriptional regulator
FA582_RS00135	COG2247	cell wall binding repeat
FA582_RS00135	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA582_RS00155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FA582_RS00160	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FA582_RS00160	COG2755	lipolytic protein G-D-S-L family
FA582_RS00195	COG0515	serine threonine protein kinase
FA582_RS00235	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FA582_RS00260	COG0640	Transcriptional regulator
FA582_RS00285	COG0531	amino acid
FA582_RS00330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FA582_RS00360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FA582_RS00400	COG4974	Belongs to the 'phage' integrase family
FA582_RS00450	COG1233	COG1233 Phytoene dehydrogenase and related
FA582_RS00455	COG2226	methyltransferase
FA582_RS00460	COG1131	(ABC) transporter
FA582_RS00490	COG1404	Belongs to the peptidase S8 family
FA582_RS00505	COG1966	Carbon starvation protein
FA582_RS00515	COG2197	response regulator
FA582_RS00520	COG4585	Histidine kinase
FA582_RS00525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FA582_RS00530	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FA582_RS00535	COG1984	allophanate hydrolase subunit 2
FA582_RS00540	COG1793	dna ligase
FA582_RS00565	COG0318	PFAM AMP-dependent synthetase and ligase
FA582_RS00595	COG1609	Transcriptional regulator
FA582_RS00610	COG0395	ABC-type sugar transport system, permease component
FA582_RS00655	COG0154	amidase activity
FA582_RS00690	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FA582_RS00700	COG0531	amino acid
FA582_RS00705	COG2186	Transcriptional regulator
FA582_RS00735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FA582_RS00785	COG1090	epimerase
FA582_RS00795	COG1105	Belongs to the carbohydrate kinase PfkB family
FA582_RS00800	COG0191	fructose-bisphosphate aldolase activity
FA582_RS00810	COG1174	glycine betaine transport
FA582_RS00825	COG0789	Transcriptional regulator
FA582_RS00835	COG0737	Belongs to the 5'-nucleotidase family
FA582_RS00835	COG1525	nuclease
FA582_RS00835	COG4085	toxin activity
FA582_RS00890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FA582_RS00900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FA582_RS00900	COG0425	Belongs to the sulfur carrier protein TusA family
FA582_RS00965	COG1674	ftsk spoiiie
FA582_RS01075	COG1652	LysM domain
FA582_RS01090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FA582_RS01090	COG2755	lipolytic protein G-D-S-L family
FA582_RS01115	COG1653	transport
FA582_RS01120	COG1175	transmembrane transport
FA582_RS01125	COG0395	ABC-type sugar transport system, permease component
FA582_RS01135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FA582_RS01140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FA582_RS01145	COG1024	Enoyl-CoA hydratase
FA582_RS01155	COG1215	transferase activity, transferring glycosyl groups
FA582_RS01170	COG1803	Methylglyoxal synthase
FA582_RS01170	COG1597	lipid kinase activity
FA582_RS01175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FA582_RS01180	COG4585	Histidine kinase
FA582_RS01185	COG2197	response regulator
FA582_RS01190	COG4152	abc transporter atp-binding protein
FA582_RS01200	COG0561	phosphatase activity
FA582_RS01205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA582_RS01225	COG1937	Protein conserved in bacteria
FA582_RS01235	COG3173	Aminoglycoside phosphotransferase
FA582_RS01245	COG1278	Cold shock
FA582_RS01250	COG3609	addiction module antidote protein, CC2985 family
FA582_RS01255	COG2337	Toxic component of a toxin-antitoxin (TA) module
FA582_RS01265	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FA582_RS01300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FA582_RS01320	COG1132	(ABC) transporter
FA582_RS01330	COG1294	oxidase, subunit
FA582_RS01335	COG1271	oxidase subunit
FA582_RS01350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FA582_RS01375	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS01380	COG1136	(ABC) transporter
FA582_RS01385	COG1136	(ABC) transporter
FA582_RS01385	COG0577	efflux transmembrane transporter activity
FA582_RS01420	COG1250	3-hydroxyacyl-CoA dehydrogenase
FA582_RS01445	COG0494	nUDIX hydrolase
FA582_RS01455	COG0813	purine-nucleoside phosphorylase activity
FA582_RS01465	COG2133	pyrroloquinoline quinone binding
FA582_RS01485	COG1819	glycosyl
FA582_RS01505	COG0582	viral genome integration into host DNA
FA582_RS01545	COG0668	transmembrane transport
FA582_RS01555	COG1024	Enoyl-CoA hydratase
FA582_RS01560	COG1764	response to oxidative stress
FA582_RS01600	COG2072	flavoprotein involved in K transport
FA582_RS01640	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FA582_RS01665	COG1309	transcriptional regulator
FA582_RS01670	COG0657	acetylesterase activity
FA582_RS01710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FA582_RS01715	COG1230	cation diffusion facilitator family transporter
FA582_RS01745	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FA582_RS01755	COG0785	Cytochrome C biogenesis protein
FA582_RS01765	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA582_RS01820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FA582_RS01830	COG0789	Transcriptional regulator
FA582_RS01860	COG0443	Heat shock 70 kDa protein
FA582_RS01865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FA582_RS01870	COG0484	heat shock protein binding
FA582_RS01875	COG0789	Transcriptional regulator
FA582_RS01890	COG1131	(ABC) transporter
FA582_RS01895	COG4585	Histidine kinase
FA582_RS01900	COG2197	response regulator
FA582_RS01905	COG0745	RESPONSE REGULATOR receiver
FA582_RS01910	COG5002	protein histidine kinase activity
FA582_RS01940	COG0477	Major facilitator Superfamily
FA582_RS01955	COG0428	transporter
FA582_RS01965	COG0542	response to heat
FA582_RS01985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FA582_RS01995	COG0477	Major facilitator Superfamily
FA582_RS02000	COG0328	RNA-DNA hybrid ribonuclease activity
FA582_RS02030	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FA582_RS02045	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FA582_RS02060	COG1305	Transglutaminase-like
FA582_RS02065	COG1305	Transglutaminase-like
FA582_RS02095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FA582_RS02130	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FA582_RS02135	COG0151	Belongs to the GarS family
FA582_RS02155	COG0204	Acyl-transferase
FA582_RS02155	COG0318	PFAM AMP-dependent synthetase and ligase
FA582_RS02160	COG0546	phosphoglycolate phosphatase activity
FA582_RS02165	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FA582_RS02185	COG1863	multisubunit Na H antiporter MnhE subunit
FA582_RS02190	COG0651	ATP synthesis coupled electron transport
FA582_RS02200	COG2111	Na H antiporter
FA582_RS02200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA582_RS02205	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FA582_RS02210	COG0789	Transcriptional regulator
FA582_RS02215	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FA582_RS02220	COG0659	secondary active sulfate transmembrane transporter activity
FA582_RS02235	COG1408	metallophosphoesterase
FA582_RS02245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FA582_RS02265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FA582_RS02270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FA582_RS02280	COG0494	nUDIX hydrolase
FA582_RS02335	COG1111	helicase
FA582_RS02335	COG1205	dead DEAH box helicase
FA582_RS02340	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FA582_RS02345	COG2890	protein-(glutamine-N5) methyltransferase activity
FA582_RS02355	COG1754	DNA topoisomerase type I activity
FA582_RS02355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FA582_RS02360	COG0626	cystathionine gamma-synthase activity
FA582_RS02370	COG1404	Belongs to the peptidase S8 family
FA582_RS02370	COG4412	M6 family metalloprotease domain protein
FA582_RS02385	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FA582_RS02390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FA582_RS02410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FA582_RS02415	COG2027	D-alanyl-D-alanine carboxypeptidase
FA582_RS02425	COG0037	tRNA processing
FA582_RS02445	COG0302	gtp cyclohydrolase
FA582_RS02455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FA582_RS02465	COG0649	NAD binding
FA582_RS02475	COG0530	calcium, potassium:sodium antiporter activity
FA582_RS02490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FA582_RS02505	COG3285	dna ligase
FA582_RS02505	COG1793	dna ligase
FA582_RS02515	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FA582_RS02530	COG0791	NLP P60 protein
FA582_RS02530	COG1388	LysM domain
FA582_RS02530	COG3103	Sh3 type 3 domain protein
FA582_RS02545	COG1194	a g-specific adenine glycosylase
FA582_RS02550	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FA582_RS02555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FA582_RS02560	COG0248	Ppx GppA phosphatase
FA582_RS02565	COG1082	Xylose isomerase domain protein TIM barrel
FA582_RS02570	COG0506	proline dehydrogenase activity
FA582_RS02575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FA582_RS02585	COG0123	including yeast histone deacetylase and acetoin utilization protein
FA582_RS02605	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FA582_RS02610	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FA582_RS02620	COG1648	precorrin-2 dehydrogenase activity
FA582_RS02620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FA582_RS02625	COG0113	porphobilinogen synthase activity
FA582_RS02630	COG1846	Transcriptional regulator
FA582_RS02635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FA582_RS02640	COG0406	alpha-ribazole phosphatase activity
FA582_RS02650	COG0785	Cytochrome C biogenesis protein
FA582_RS02655	COG1333	cytochrome c biogenesis protein
FA582_RS02660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA582_RS02700	COG4948	Mandelate Racemase Muconate Lactonizing
FA582_RS02720	COG1278	Cold shock
FA582_RS02735	COG2252	PERMEase
FA582_RS02760	COG0259	pyridoxamine-phosphate oxidase activity
FA582_RS02765	COG1321	iron dependent repressor
FA582_RS02770	COG1388	LysM domain
FA582_RS02770	COG0791	NLP P60 protein
FA582_RS02770	COG3103	Sh3 type 3 domain protein
FA582_RS02775	COG1253	flavin adenine dinucleotide binding
FA582_RS02785	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FA582_RS02790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FA582_RS02845	COG4608	Belongs to the ABC transporter superfamily
FA582_RS02855	COG0477	Major facilitator Superfamily
FA582_RS02870	COG1970	mechanosensitive ion channel activity
FA582_RS02900	COG0315	cyclic pyranopterin monophosphate synthase activity
FA582_RS02920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FA582_RS02955	COG1053	succinate dehydrogenase
FA582_RS02960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FA582_RS02990	COG1595	DNA-templated transcription, initiation
FA582_RS03005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA582_RS03010	COG0084	hydrolase, TatD family'
FA582_RS03015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FA582_RS03025	COG0488	(ABC) transporter
FA582_RS03035	COG0667	Aldo Keto reductase
FA582_RS03050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FA582_RS03055	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FA582_RS03060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FA582_RS03065	COG0193	aminoacyl-tRNA hydrolase activity
FA582_RS03080	COG1842	Phage shock protein A
FA582_RS03140	COG0148	phosphopyruvate hydratase activity
FA582_RS03195	COG2354	Protein conserved in bacteria
FA582_RS03200	COG0183	Belongs to the thiolase family
FA582_RS03205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA582_RS03210	COG0318	PFAM AMP-dependent synthetase and ligase
FA582_RS03215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA582_RS03230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FA582_RS03255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FA582_RS03260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FA582_RS03270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FA582_RS03285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FA582_RS03290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FA582_RS03310	COG1072	(Pantothenic acid kinase))
FA582_RS03315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FA582_RS03320	COG0736	holo-[acyl-carrier-protein] synthase activity
FA582_RS03340	COG0477	Major facilitator Superfamily
FA582_RS03345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA582_RS03355	COG0066	3-isopropylmalate dehydratase activity
FA582_RS03365	COG0473	3-isopropylmalate dehydrogenase activity
FA582_RS03370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FA582_RS03375	COG0802	atpase or kinase
FA582_RS03380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA582_RS03410	COG0567	Dehydrogenase, E1 component
FA582_RS03410	COG0508	dehydrogenase complex catalyzes the overall conversion of
FA582_RS03430	COG0709	Synthesizes selenophosphate from selenide and ATP
FA582_RS03445	COG0277	FAD linked oxidase domain protein
FA582_RS03450	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FA582_RS03465	COG0018	arginyl-trna synthetase
FA582_RS03470	COG0460	homoserine dehydrogenase
FA582_RS03480	COG0254	rRNA binding
FA582_RS03485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FA582_RS03490	COG2890	protein-(glutamine-N5) methyltransferase activity
FA582_RS03500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FA582_RS03505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA582_RS03520	COG0356	it plays a direct role in the translocation of protons across the membrane
FA582_RS03525	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA582_RS03530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FA582_RS03535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA582_RS03540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FA582_RS03545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FA582_RS03550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FA582_RS03555	COG2233	PERMEase
FA582_RS03560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FA582_RS03590	COG0463	Glycosyl transferase, family 2
FA582_RS03595	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FA582_RS03600	COG1250	3-hydroxyacyl-CoA dehydrogenase
FA582_RS03620	COG0346	lactoylglutathione lyase activity
FA582_RS03630	COG0183	Belongs to the thiolase family
FA582_RS03660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FA582_RS03665	COG0366	Alpha amylase catalytic
FA582_RS03670	COG0366	Alpha amylase catalytic
FA582_RS03680	COG1216	Glycosyl transferase, family 2
FA582_RS03690	COG1024	Enoyl-CoA hydratase
FA582_RS03710	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FA582_RS03730	COG0482	sulfurtransferase activity
FA582_RS03750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FA582_RS03755	COG4106	trans-aconitate 2-methyltransferase activity
FA582_RS03760	COG0477	Major facilitator Superfamily
FA582_RS03775	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA582_RS03780	COG0154	amidase activity
FA582_RS03785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA582_RS03810	COG0842	Transport permease protein
FA582_RS03820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FA582_RS03835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FA582_RS03850	COG0024	Methionine aminopeptidase
FA582_RS03860	COG0179	Fumarylacetoacetate (FAA) hydrolase
FA582_RS03865	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FA582_RS03880	COG1253	flavin adenine dinucleotide binding
FA582_RS03895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FA582_RS03900	COG2364	Membrane
FA582_RS03915	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FA582_RS03920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FA582_RS03925	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FA582_RS03930	COG0083	homoserine kinase activity
FA582_RS03950	COG2217	Heavy metal translocating P-type atpase
FA582_RS03960	COG0156	8-amino-7-oxononanoate synthase activity
FA582_RS03965	COG1063	alcohol dehydrogenase
FA582_RS03980	COG1295	ribonuclease BN
FA582_RS04020	COG1605	Chorismate mutase
FA582_RS04020	COG0287	Prephenate dehydrogenase
FA582_RS04025	COG1160	GTP binding
FA582_RS04030	COG1160	GTP binding
FA582_RS04045	COG0564	pseudouridine synthase activity
FA582_RS04060	COG1404	Belongs to the peptidase S8 family
FA582_RS04065	COG1946	Acyl-CoA thioesterase
FA582_RS04070	COG0667	Aldo Keto reductase
FA582_RS04080	COG1556	Lactate utilization protein
FA582_RS04085	COG1139	Iron-sulfur cluster binding protein
FA582_RS04090	COG0247	lactate metabolic process
FA582_RS04115	COG2814	Major facilitator Superfamily
FA582_RS04125	COG1253	flavin adenine dinucleotide binding
FA582_RS04130	COG0366	Alpha amylase catalytic
FA582_RS04145	COG0668	transmembrane transport
FA582_RS04165	COG1136	(ABC) transporter
FA582_RS04175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FA582_RS04180	COG0698	ribose 5-phosphate isomerase
FA582_RS04190	COG0431	NADPH-dependent FMN reductase
FA582_RS04205	COG0544	peptidyl-prolyl cis-trans isomerase activity
FA582_RS04220	COG0740	serine-type endopeptidase activity
FA582_RS04225	COG0740	serine-type endopeptidase activity
FA582_RS04235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FA582_RS04245	COG2149	membrane
FA582_RS04260	COG0714	Associated with various cellular activities
FA582_RS04275	COG0525	valine-tRNA ligase activity
FA582_RS04280	COG1115	amino acid carrier protein
FA582_RS04295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FA582_RS04300	COG0285	dihydrofolate synthase activity
FA582_RS04320	COG1968	undecaprenyl-diphosphatase activity
FA582_RS04325	COG0105	UTP biosynthetic process
FA582_RS04370	COG1077	Cell shape determining protein MreB Mrl
FA582_RS04385	COG0768	penicillin binding
FA582_RS04395	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FA582_RS04410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FA582_RS04420	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FA582_RS04425	COG1185	polyribonucleotide nucleotidyltransferase activity
FA582_RS04440	COG3396	Phenylacetate-CoA oxygenase
FA582_RS04445	COG3460	Phenylacetate-CoA oxygenase
FA582_RS04450	COG3396	Phenylacetate-CoA oxygenase
FA582_RS04455	COG2151	metal-sulfur cluster biosynthetic enzyme
FA582_RS04460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FA582_RS04470	COG0424	maF-like protein
FA582_RS04490	COG4106	trans-aconitate 2-methyltransferase activity
FA582_RS04505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FA582_RS04515	COG1024	Enoyl-CoA hydratase
FA582_RS04520	COG0745	RESPONSE REGULATOR receiver
FA582_RS04525	COG2205	protein histidine kinase activity
FA582_RS04540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FA582_RS04550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA582_RS04560	COG0515	serine threonine protein kinase
FA582_RS04565	COG1316	TRANSCRIPTIONal
FA582_RS04600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FA582_RS04630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA582_RS04645	COG3483	tryptophan 2,3-dioxygenase activity
FA582_RS04660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FA582_RS04665	COG0745	RESPONSE REGULATOR receiver
FA582_RS04670	COG5000	phosphorelay sensor kinase activity
FA582_RS04670	COG5002	protein histidine kinase activity
FA582_RS04675	COG5401	PFAM Sporulation and spore germination
FA582_RS04685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FA582_RS04690	COG3214	Protein conserved in bacteria
FA582_RS04700	COG0653	protein targeting
FA582_RS04740	COG1012	belongs to the aldehyde dehydrogenase family
FA582_RS04755	COG2902	Dehydrogenase
FA582_RS04795	COG0574	Belongs to the PEP-utilizing enzyme family
FA582_RS04795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FA582_RS04800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FA582_RS04810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FA582_RS04820	COG0475	glutathione-regulated potassium exporter activity
FA582_RS04825	COG2813	Specifically methylates the guanine in position
FA582_RS04830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FA582_RS04840	COG4221	oxidoreductase activity
FA582_RS04860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FA582_RS04895	COG0268	Binds directly to 16S ribosomal RNA
FA582_RS04900	COG0495	leucyl-tRNA aminoacylation
FA582_RS04905	COG1307	EDD domain protein, DegV family
FA582_RS04915	COG1234	tRNA 3'-trailer cleavage
FA582_RS04920	COG0583	DNA-binding transcription factor activity
FA582_RS04930	COG0745	RESPONSE REGULATOR receiver
FA582_RS04935	COG2205	protein histidine kinase activity
FA582_RS04950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FA582_RS04970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FA582_RS04975	COG0514	ATP-dependent DNA helicase (RecQ)
FA582_RS04990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA582_RS05000	COG4585	Histidine kinase
FA582_RS05005	COG2197	response regulator
FA582_RS05020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FA582_RS05025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA582_RS05080	COG3547	Transposase (IS116 IS110 IS902 family)
FA582_RS05115	COG1129	ABC transporter
FA582_RS05140	COG0673	inositol 2-dehydrogenase activity
FA582_RS05185	COG1064	alcohol dehydrogenase
FA582_RS05205	COG0662	Cupin 2, conserved barrel domain protein
FA582_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS05225	COG0515	serine threonine protein kinase
FA582_RS05245	COG1716	ATPase activity
FA582_RS05315	COG2733	membrane
FA582_RS05325	COG1643	Atp-dependent helicase
FA582_RS05330	COG2154	pterin-4-alpha-carbinolamine dehydratase
FA582_RS05335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FA582_RS05335	COG0237	dephospho-CoA kinase activity
FA582_RS05340	COG0823	Involved in the tonB-independent uptake of proteins
FA582_RS05340	COG1506	peptidase
FA582_RS05365	COG0589	response to stress
FA582_RS05370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FA582_RS05385	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FA582_RS05390	COG1305	Transglutaminase-like
FA582_RS05400	COG0714	Associated with various cellular activities
FA582_RS05405	COG2001	Belongs to the MraZ family
FA582_RS05410	COG0275	rRNA processing
FA582_RS05420	COG0768	penicillin binding
FA582_RS05430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA582_RS05435	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FA582_RS05445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FA582_RS05450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FA582_RS05455	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FA582_RS05460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FA582_RS05465	COG1496	oxidoreductase activity
FA582_RS05470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FA582_RS05475	COG1799	cell septum assembly
FA582_RS05505	COG0587	DNA-directed DNA polymerase activity
FA582_RS05525	COG1012	belongs to the aldehyde dehydrogenase family
FA582_RS05535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FA582_RS05575	COG0174	glutamine synthetase
FA582_RS05585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FA582_RS05590	COG0438	transferase activity, transferring glycosyl groups
FA582_RS05595	COG0398	Pfam SNARE associated Golgi protein
FA582_RS05600	COG0438	transferase activity, transferring glycosyl groups
FA582_RS05615	COG0321	lipoyl(octanoyl) transferase activity
FA582_RS05620	COG0515	serine threonine protein kinase
FA582_RS05635	COG0508	dehydrogenase complex catalyzes the overall conversion of
FA582_RS05640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FA582_RS05645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FA582_RS05670	COG0435	Glutathione S-transferase
FA582_RS05675	COG0180	Tryptophanyl-tRNA synthetase
FA582_RS05690	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FA582_RS05695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FA582_RS05700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FA582_RS05715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FA582_RS05725	COG1845	cytochrome c oxidase, subunit III
FA582_RS05730	COG2010	Cytochrome c
FA582_RS05735	COG0723	plastoquinol--plastocyanin reductase activity
FA582_RS05740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA582_RS05765	COG1022	Amp-dependent synthetase and ligase
FA582_RS05770	COG1940	carbohydrate kinase activity
FA582_RS05775	COG1940	carbohydrate kinase activity
FA582_RS05795	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FA582_RS05810	COG2815	serine threonine protein kinase
FA582_RS05810	COG0515	serine threonine protein kinase
FA582_RS05815	COG2815	serine threonine protein kinase
FA582_RS05815	COG0515	serine threonine protein kinase
FA582_RS05825	COG1388	LysM domain
FA582_RS05825	COG3942	CHAP domain
FA582_RS05835	COG0142	geranyltranstransferase activity
FA582_RS05850	COG0587	DNA-directed DNA polymerase activity
FA582_RS05855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FA582_RS05865	COG1595	DNA-templated transcription, initiation
FA582_RS05895	COG0513	Belongs to the DEAD box helicase family
FA582_RS05920	COG0733	neurotransmitter:sodium symporter activity
FA582_RS05925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FA582_RS05955	COG1703	isobutyryl-CoA mutase activity
FA582_RS05955	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FA582_RS05955	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FA582_RS05960	COG0513	Belongs to the DEAD box helicase family
FA582_RS05965	COG2267	carboxylic ester hydrolase activity
FA582_RS05970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FA582_RS05990	COG2814	Major facilitator Superfamily
FA582_RS06015	COG4974	Belongs to the 'phage' integrase family
FA582_RS06055	COG0395	ABC-type sugar transport system, permease component
FA582_RS06095	COG2755	lipolytic protein G-D-S-L family
FA582_RS06095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FA582_RS06100	COG1960	acyl-CoA dehydrogenase activity
FA582_RS06115	COG0667	Aldo Keto reductase
FA582_RS06130	COG3046	protein related to deoxyribodipyrimidine photolyase
FA582_RS06150	COG2195	Cleaves the N-terminal amino acid of tripeptides
FA582_RS06175	COG1024	Enoyl-CoA hydratase
FA582_RS06195	COG3268	Saccharopine dehydrogenase
FA582_RS06225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FA582_RS06235	COG1012	belongs to the aldehyde dehydrogenase family
FA582_RS06295	COG1183	phosphatidylcholine synthase activity
FA582_RS06330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FA582_RS06340	COG2337	Toxic component of a toxin-antitoxin (TA) module
FA582_RS06410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FA582_RS06460	COG4941	Belongs to the sigma-70 factor family
FA582_RS06465	COG1760	l-serine dehydratase
FA582_RS06475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FA582_RS06480	COG1472	Belongs to the glycosyl hydrolase 3 family
FA582_RS06485	COG0395	ABC-type sugar transport system, permease component
FA582_RS06490	COG1175	transmembrane transport
FA582_RS06495	COG2182	Extracellular solute-binding protein
FA582_RS06500	COG2188	Transcriptional regulator
FA582_RS06505	COG1649	PFAM Uncharacterised BCR, COG1649
FA582_RS06510	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FA582_RS06515	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FA582_RS06520	COG0363	glucosamine-6-phosphate deaminase activity
FA582_RS06525	COG2031	fatty acid transporter
FA582_RS06570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FA582_RS06575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FA582_RS06580	COG1228	amidohydrolase
FA582_RS06585	COG2423	ornithine cyclodeaminase activity
FA582_RS06590	COG2267	carboxylic ester hydrolase activity
FA582_RS06645	COG1435	thymidine kinase activity
FA582_RS06655	COG2860	membrane
FA582_RS06660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FA582_RS06665	COG0483	inositol monophosphate 1-phosphatase activity
FA582_RS06675	COG0756	dUTP diphosphatase activity
FA582_RS06690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FA582_RS06695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA582_RS06700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FA582_RS06705	COG2514	catechol 2,3-dioxygenase activity
FA582_RS06710	COG2326	polyphosphate kinase activity
FA582_RS06720	COG0384	phenazine biosynthesis protein PhzF
FA582_RS06730	COG1597	lipid kinase activity
FA582_RS06750	COG1175	transmembrane transport
FA582_RS06755	COG0395	ABC-type sugar transport system, permease component
FA582_RS06790	COG1757	Na H antiporter
FA582_RS06825	COG0438	transferase activity, transferring glycosyl groups
FA582_RS06835	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FA582_RS06840	COG0352	thiamine-phosphate diphosphorylase activity
FA582_RS06845	COG0351	phosphomethylpyrimidine kinase
FA582_RS06855	COG1132	(ABC) transporter
FA582_RS06880	COG2267	carboxylic ester hydrolase activity
FA582_RS06885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FA582_RS06900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA582_RS06900	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FA582_RS06915	COG0175	sulfate reduction
FA582_RS06940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FA582_RS06955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FA582_RS06970	COG3253	May function as heme-dependent peroxidase
FA582_RS06980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FA582_RS06985	COG1793	dna ligase
FA582_RS06985	COG3285	dna ligase
FA582_RS06995	COG1793	dna ligase
FA582_RS07010	COG2326	polyphosphate kinase activity
FA582_RS07045	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FA582_RS07080	COG4974	Belongs to the 'phage' integrase family
FA582_RS07110	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS07135	COG0297	glycogen (starch) synthase activity
FA582_RS07160	COG0546	phosphoglycolate phosphatase activity
FA582_RS07165	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS07175	COG3591	Belongs to the peptidase S1B family
FA582_RS07200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FA582_RS07205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FA582_RS07245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FA582_RS07265	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FA582_RS07315	COG2385	sporulation resulting in formation of a cellular spore
FA582_RS07320	COG0217	transcriptional regulatory protein
FA582_RS07325	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FA582_RS07330	COG0632	four-way junction helicase activity
FA582_RS07335	COG2255	four-way junction helicase activity
FA582_RS07345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FA582_RS07350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FA582_RS07355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA582_RS07360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FA582_RS07370	COG1196	nuclear chromosome segregation
FA582_RS07385	COG2357	RelA SpoT domain protein
FA582_RS07390	COG0124	histidyl-tRNA synthetase
FA582_RS07405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FA582_RS07410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FA582_RS07415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA582_RS07420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FA582_RS07420	COG0131	Imidazoleglycerol-phosphate dehydratase
FA582_RS07440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FA582_RS07440	COG0140	phosphoribosyl-ATP diphosphatase activity
FA582_RS07470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FA582_RS07475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FA582_RS07485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FA582_RS07520	COG3119	arylsulfatase activity
FA582_RS07525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FA582_RS07530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FA582_RS07550	COG0247	lactate metabolic process
FA582_RS07550	COG0277	FAD linked oxidase domain protein
FA582_RS07555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FA582_RS07560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FA582_RS07565	COG0006	proline dipeptidase activity
FA582_RS07575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FA582_RS07580	COG0154	amidase activity
FA582_RS07615	COG0509	glycine decarboxylation via glycine cleavage system
FA582_RS07640	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FA582_RS07640	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FA582_RS07650	COG0406	alpha-ribazole phosphatase activity
FA582_RS07670	COG0596	Alpha beta hydrolase
FA582_RS07675	COG0009	L-threonylcarbamoyladenylate synthase
FA582_RS07680	COG1937	Protein conserved in bacteria
FA582_RS07685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FA582_RS07685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FA582_RS07700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FA582_RS07755	COG0676	glucose-6-phosphate 1-epimerase activity
FA582_RS07770	COG2270	Major facilitator Superfamily
FA582_RS07780	COG3030	protein affecting phage T7 exclusion by the F plasmid
FA582_RS07785	COG0463	Glycosyl transferase, family 2
FA582_RS07800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FA582_RS07805	COG1522	sequence-specific DNA binding
FA582_RS07820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA582_RS07830	COG0183	Belongs to the thiolase family
FA582_RS07835	COG4581	dead DEAH box helicase
FA582_RS07845	COG0805	protein transport
FA582_RS07850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FA582_RS07855	COG2378	regulation of single-species biofilm formation
FA582_RS07880	COG2066	Belongs to the glutaminase family
FA582_RS07895	COG0545	Peptidyl-prolyl cis-trans isomerase
FA582_RS07900	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FA582_RS07920	COG1222	aaa ATPase
FA582_RS07930	COG1994	Peptidase M50
FA582_RS07930	COG0517	IMP dehydrogenase activity
FA582_RS07950	COG0215	cysteine-tRNA ligase activity
FA582_RS07965	COG0406	alpha-ribazole phosphatase activity
FA582_RS07970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA582_RS07985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FA582_RS08030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA582_RS08035	COG1725	Transcriptional regulator
FA582_RS08095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FA582_RS08100	COG1881	PFAM PEBP family protein
FA582_RS08110	COG0385	Bile acid
FA582_RS08130	COG1119	ATPase activity
FA582_RS08145	COG0297	glycogen (starch) synthase activity
FA582_RS08155	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FA582_RS08160	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS08180	COG1132	(ABC) transporter
FA582_RS08185	COG0488	(ABC) transporter
FA582_RS08195	COG1823	symporter activity
FA582_RS08205	COG2151	metal-sulfur cluster biosynthetic enzyme
FA582_RS08210	COG0822	iron-sulfur transferase activity
FA582_RS08220	COG0396	ATPase activity
FA582_RS08260	COG0109	protoheme IX farnesyltransferase activity
FA582_RS08270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FA582_RS08275	COG0166	Belongs to the GPI family
FA582_RS08295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FA582_RS08300	COG0149	triose-phosphate isomerase activity
FA582_RS08305	COG0126	phosphoglycerate kinase activity
FA582_RS08310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FA582_RS08315	COG1481	regulation of sporulation
FA582_RS08325	COG1660	Displays ATPase and GTPase activities
FA582_RS08330	COG0322	excinuclease ABC activity
FA582_RS08340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FA582_RS08345	COG0067	glutamate synthase
FA582_RS08345	COG0069	glutamate synthase activity
FA582_RS08345	COG0070	glutamate synthase
FA582_RS08370	COG0556	nucleotide-excision repair
FA582_RS08380	COG0539	negative regulation of cytoplasmic translation
FA582_RS08385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FA582_RS08450	COG0159	tryptophan synthase activity
FA582_RS08460	COG0134	indole-3-glycerol-phosphate synthase activity
FA582_RS08475	COG1132	(ABC) transporter
FA582_RS08480	COG1132	(ABC) transporter
FA582_RS08490	COG4129	membrane
FA582_RS08500	COG3201	nicotinamide mononucleotide transporter
FA582_RS08505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FA582_RS08515	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FA582_RS08535	COG0747	negative chemotaxis
FA582_RS08545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FA582_RS08555	COG1758	RNA polymerase activity
FA582_RS08560	COG0194	GDP metabolic process
FA582_RS08570	COG0284	orotidine-5'-phosphate decarboxylase activity
FA582_RS08580	COG0543	2 iron, 2 sulfur cluster binding
FA582_RS08585	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FA582_RS08590	COG0505	Belongs to the CarA family
FA582_RS08595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FA582_RS08600	COG0540	Belongs to the ATCase OTCase family
FA582_RS08605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FA582_RS08610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FA582_RS08615	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FA582_RS08650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FA582_RS08655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FA582_RS08660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FA582_RS08690	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FA582_RS08700	COG0504	CTP synthase activity
FA582_RS08735	COG0497	DNA recombination
FA582_RS08740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FA582_RS08755	COG0647	UMP catabolic process
FA582_RS08780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FA582_RS08785	COG2094	Belongs to the DNA glycosylase MPG family
FA582_RS08790	COG0165	Argininosuccinate lyase
FA582_RS08795	COG1438	arginine binding
FA582_RS08805	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS08815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FA582_RS08825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA582_RS08830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FA582_RS08835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FA582_RS08840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FA582_RS08845	COG1404	Belongs to the peptidase S8 family
FA582_RS08845	COG4412	M6 family metalloprotease domain protein
FA582_RS08865	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FA582_RS08870	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FA582_RS08875	COG0174	glutamine synthetase
FA582_RS08885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA582_RS08900	COG1940	carbohydrate kinase activity
FA582_RS08915	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FA582_RS08930	COG0561	phosphatase activity
FA582_RS08935	COG0557	exoribonuclease II activity
FA582_RS08940	COG3022	response to hydroperoxide
FA582_RS08960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FA582_RS08985	COG0584	glycerophosphoryl diester phosphodiesterase
FA582_RS09000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA582_RS09005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA582_RS09010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FA582_RS09015	COG0438	transferase activity, transferring glycosyl groups
FA582_RS09035	COG1126	abc transporter atp-binding protein
FA582_RS09040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA582_RS09045	COG0765	amino acid transport
FA582_RS09050	COG0765	amino acid transport
FA582_RS09065	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FA582_RS09070	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS09075	COG0753	catalase activity
FA582_RS09080	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FA582_RS09085	COG1295	ribonuclease BN
FA582_RS09105	COG1309	transcriptional regulator
FA582_RS09120	COG0477	Major facilitator Superfamily
FA582_RS09125	COG2801	Transposase and inactivated derivatives
FA582_RS09150	COG0358	DNA primase activity
FA582_RS09155	COG2814	Major facilitator Superfamily
FA582_RS09195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FA582_RS09230	COG0693	protein deglycase activity
FA582_RS09240	COG0584	glycerophosphoryl diester phosphodiesterase
FA582_RS09255	COG0423	glycine-tRNA ligase activity
FA582_RS09265	COG3443	Belongs to the bacterial solute-binding protein 9 family
FA582_RS09265	COG0803	Belongs to the bacterial solute-binding protein 9 family
FA582_RS09270	COG1121	(ABC) transporter
FA582_RS09285	COG2226	methyltransferase
FA582_RS09295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FA582_RS09300	COG1381	Involved in DNA repair and RecF pathway recombination
FA582_RS09310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FA582_RS09315	COG1461	Dihydroxyacetone kinase
FA582_RS09320	COG2376	Dihydroxyacetone kinase
FA582_RS09330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FA582_RS09340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FA582_RS09350	COG0477	Major facilitator Superfamily
FA582_RS09360	COG0484	heat shock protein binding
FA582_RS09365	COG1420	regulation of RNA biosynthetic process
FA582_RS09370	COG0114	fumarate hydratase activity
FA582_RS09410	COG2326	polyphosphate kinase activity
FA582_RS09415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FA582_RS09420	COG0481	GTPase activity
FA582_RS09430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FA582_RS09440	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FA582_RS09445	COG0277	FAD linked oxidase domain protein
FA582_RS09450	COG0277	FAD linked oxidase domain protein
FA582_RS09455	COG0247	lactate metabolic process
FA582_RS09460	COG1620	l-lactate permease
FA582_RS09490	COG0799	negative regulation of ribosome biogenesis
FA582_RS09495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FA582_RS09505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FA582_RS09510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FA582_RS09520	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FA582_RS09525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FA582_RS09530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FA582_RS09535	COG1530	ribonuclease E activity
FA582_RS09545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FA582_RS09560	COG1070	Carbohydrate kinase
FA582_RS09565	COG1022	Amp-dependent synthetase and ligase
FA582_RS09570	COG0772	Belongs to the SEDS family
FA582_RS09585	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FA582_RS09590	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FA582_RS09610	COG0779	Required for maturation of 30S ribosomal subunits
FA582_RS09620	COG1331	Highly conserved protein containing a thioredoxin domain
FA582_RS09635	COG0442	prolyl-tRNA aminoacylation
FA582_RS09650	COG1505	serine-type exopeptidase activity
FA582_RS09660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FA582_RS09665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FA582_RS09670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FA582_RS09675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA582_RS09680	COG0765	amino acid transport
FA582_RS09685	COG1126	abc transporter atp-binding protein
FA582_RS09700	COG0456	acetyltransferase
FA582_RS09705	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FA582_RS09710	COG0750	zinc metalloprotease
FA582_RS09715	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FA582_RS09770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FA582_RS09775	COG0575	Belongs to the CDS family
FA582_RS09780	COG0233	cytoplasmic translational termination
FA582_RS09785	COG0528	UMP kinase activity
FA582_RS09795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FA582_RS09800	COG0052	Belongs to the universal ribosomal protein uS2 family
FA582_RS09815	COG4974	Belongs to the 'phage' integrase family
FA582_RS09820	COG2059	Chromate
FA582_RS09840	COG0792	nuclease activity
FA582_RS09850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FA582_RS09855	COG0681	Belongs to the peptidase S26 family
FA582_RS09860	COG0335	large ribosomal subunit rRNA binding
FA582_RS09865	COG3830	Belongs to the UPF0237 family
FA582_RS09865	COG0560	Phosphoserine phosphatase
FA582_RS09870	COG0336	Belongs to the RNA methyltransferase TrmD family
FA582_RS09875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FA582_RS09880	COG1837	Belongs to the UPF0109 family
FA582_RS09885	COG0228	four-way junction DNA binding
FA582_RS09900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FA582_RS09915	COG3663	DNA glycosylase
FA582_RS09975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FA582_RS09980	COG0571	ribonuclease III activity
FA582_RS09985	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FA582_RS09995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FA582_RS10005	COG0742	ribosomal rna small subunit methyltransferase
FA582_RS10015	COG1461	Dihydroxyacetone kinase
FA582_RS10020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FA582_RS10040	COG1181	Belongs to the D-alanine--D-alanine ligase family
FA582_RS10045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FA582_RS10060	COG0776	regulation of translation
FA582_RS10075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA582_RS10085	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FA582_RS10100	COG1335	isochorismatase
FA582_RS10120	COG0179	Fumarylacetoacetate (FAA) hydrolase
FA582_RS10135	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FA582_RS10180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA582_RS10185	COG0601	transmembrane transport
FA582_RS10195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FA582_RS10240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FA582_RS10250	COG0739	heme binding
FA582_RS10250	COG1196	nuclear chromosome segregation
FA582_RS10250	COG0741	lytic transglycosylase activity
FA582_RS10255	COG2177	Part of the ABC transporter FtsEX involved in
FA582_RS10260	COG2884	Cell division ATP-binding protein ftsE
FA582_RS10270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FA582_RS10275	COG2318	DinB family
FA582_RS10325	COG1674	ftsk spoiiie
FA582_RS10345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA582_RS10365	COG2137	regulation of response to DNA damage stimulus
FA582_RS10370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FA582_RS10390	COG2226	methyltransferase
FA582_RS10415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FA582_RS10415	COG0825	malonyl-CoA metabolic process
FA582_RS10420	COG1132	(ABC) transporter
FA582_RS10425	COG1132	(ABC) transporter
FA582_RS10435	COG1201	RNA secondary structure unwinding
FA582_RS10440	COG0488	(ABC) transporter
FA582_RS10450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FA582_RS10470	COG1396	sequence-specific DNA binding
FA582_RS10475	COG1546	Belongs to the CinA family
FA582_RS10475	COG1058	Belongs to the CinA family
FA582_RS10485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA582_RS10500	COG1674	ftsk spoiiie
FA582_RS10515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FA582_RS10520	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FA582_RS10535	COG1506	peptidase
FA582_RS10535	COG4946	Tricorn protease homolog
FA582_RS10535	COG0823	Involved in the tonB-independent uptake of proteins
FA582_RS10550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FA582_RS10555	COG1960	acyl-CoA dehydrogenase activity
FA582_RS10565	COG4770	biotin carboxylase activity
FA582_RS10580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA582_RS10630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FA582_RS10640	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FA582_RS10665	COG1079	Belongs to the binding-protein-dependent transport system permease family
FA582_RS10670	COG4603	Belongs to the binding-protein-dependent transport system permease family
FA582_RS10675	COG3845	ABC transporter
FA582_RS10680	COG1744	ABC transporter substrate-binding protein PnrA-like
FA582_RS10685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FA582_RS10685	COG1473	amidohydrolase
FA582_RS10690	COG0167	dihydroorotate dehydrogenase activity
FA582_RS10710	COG1388	LysM domain
FA582_RS10710	COG4641	Protein conserved in bacteria
FA582_RS10715	COG0039	L-malate dehydrogenase activity
FA582_RS10725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FA582_RS10740	COG0138	bifunctional purine biosynthesis protein purh
FA582_RS10765	COG0045	succinate-CoA ligase (ADP-forming) activity
FA582_RS10800	COG0519	Catalyzes the synthesis of GMP from XMP
FA582_RS10800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FA582_RS10820	COG0516	GMP reductase activity
FA582_RS10835	COG0459	protein refolding
FA582_RS10840	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FA582_RS10865	COG0569	domain protein
FA582_RS10875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FA582_RS10885	COG1214	PFAM Peptidase M22, glycoprotease
FA582_RS10885	COG0456	acetyltransferase
FA582_RS10895	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA582_RS10915	COG1595	DNA-templated transcription, initiation
FA582_RS10925	COG2135	peptidase activity
FA582_RS10945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FA582_RS10950	COG1162	GTPase activity
FA582_RS10955	COG0483	inositol monophosphate 1-phosphatase activity
FA582_RS10965	COG0612	Peptidase, M16
FA582_RS10975	COG1615	UPF0182 protein
FA582_RS10985	COG3480	Lon protease (S16) C-terminal proteolytic domain
FA582_RS10990	COG0314	molybdopterin synthase activity
FA582_RS11025	COG0210	DNA helicase
FA582_RS11050	COG0513	Belongs to the DEAD box helicase family
FA582_RS11070	COG0006	proline dipeptidase activity
FA582_RS11080	COG2239	Acts as a magnesium transporter
FA582_RS11100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FA582_RS11105	COG1595	DNA-templated transcription, initiation
FA582_RS11135	COG0519	Catalyzes the synthesis of GMP from XMP
FA582_RS11145	COG1611	Belongs to the LOG family
FA582_RS11165	COG2720	vancomycin resistance protein
FA582_RS11175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FA582_RS11180	COG1217	gtp-binding protein TYPA
FA582_RS11185	COG0494	nUDIX hydrolase
FA582_RS11190	COG0747	negative chemotaxis
FA582_RS11195	COG0601	transmembrane transport
FA582_RS11200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA582_RS11205	COG0444	Belongs to the ABC transporter superfamily
FA582_RS11210	COG4608	Belongs to the ABC transporter superfamily
FA582_RS11215	COG0505	Belongs to the CarA family
FA582_RS11230	COG2838	Isocitrate dehydrogenase
FA582_RS11235	COG0306	phosphate transporter
FA582_RS11245	COG0432	Pfam Uncharacterised protein family UPF0047
FA582_RS11260	COG0477	Major facilitator Superfamily
FA582_RS11300	COG0012	GTP binding
FA582_RS11305	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FA582_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS11325	COG0318	PFAM AMP-dependent synthetase and ligase
FA582_RS11355	COG1322	Protein conserved in bacteria
FA582_RS11365	COG1126	abc transporter atp-binding protein
FA582_RS11370	COG0765	amino acid transport
FA582_RS11375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA582_RS11380	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FA582_RS11390	COG1570	exodeoxyribonuclease VII activity
FA582_RS11440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA582_RS11450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FA582_RS11455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FA582_RS11460	COG0628	permease
FA582_RS11480	COG0438	transferase activity, transferring glycosyl groups
FA582_RS11500	COG0604	alcohol dehydrogenase
FA582_RS11505	COG0101	tRNA pseudouridine synthase activity
FA582_RS11510	COG0203	ribosomal protein L17
FA582_RS11515	COG0202	RNA polymerase activity
FA582_RS11525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FA582_RS11530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FA582_RS11535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FA582_RS11540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FA582_RS11550	COG0563	adenylate kinase activity
FA582_RS11560	COG0200	Binds to the 23S rRNA
FA582_RS11565	COG1841	ribosomal large subunit assembly
FA582_RS11570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FA582_RS11575	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FA582_RS11585	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FA582_RS11595	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FA582_RS11605	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FA582_RS11610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FA582_RS11615	COG0255	Belongs to the universal ribosomal protein uL29 family
FA582_RS11620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FA582_RS11625	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FA582_RS11630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FA582_RS11635	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FA582_RS11640	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FA582_RS11645	COG0089	rRNA binding
FA582_RS11650	COG0088	Forms part of the polypeptide exit tunnel
FA582_RS11655	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FA582_RS11660	COG0051	transcription antitermination factor activity, RNA binding
FA582_RS11670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FA582_RS11675	COG0049	tRNA binding
FA582_RS11680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FA582_RS11685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FA582_RS11690	COG0085	RNA polymerase activity
FA582_RS11695	COG0222	ribosome binding
FA582_RS11700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FA582_RS11720	COG0081	regulation of translation
FA582_RS11725	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FA582_RS11735	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FA582_RS11745	COG0436	Aminotransferase
FA582_RS11760	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FA582_RS11770	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FA582_RS11795	COG0137	argininosuccinate synthase activity
FA582_RS11825	COG1131	(ABC) transporter
FA582_RS11830	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FA582_RS11840	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FA582_RS11850	COG2030	dehydratase
FA582_RS11855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FA582_RS11875	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS11910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FA582_RS11915	COG0477	Major facilitator Superfamily
FA582_RS11925	COG0477	Major facilitator Superfamily
FA582_RS11930	COG1666	GTP binding
FA582_RS11950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FA582_RS11955	COG0501	Belongs to the peptidase M48B family
FA582_RS11960	COG1007	ATP synthesis coupled electron transport
FA582_RS11965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA582_RS11975	COG0713	ATP synthesis coupled electron transport
FA582_RS11980	COG0839	Belongs to the complex I subunit 6 family
FA582_RS11985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA582_RS11990	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FA582_RS12010	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA582_RS12015	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA582_RS12020	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA582_RS12035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA582_RS12055	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FA582_RS12055	COG0674	pyruvate-flavodoxin oxidoreductase activity
FA582_RS12060	COG1013	pyruvate-flavodoxin oxidoreductase activity
FA582_RS12075	COG2409	Drug exporters of the RND superfamily
FA582_RS12090	COG0142	geranyltranstransferase activity
FA582_RS12095	COG1007	ATP synthesis coupled electron transport
FA582_RS12105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA582_RS12120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA582_RS12125	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FA582_RS12135	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FA582_RS12145	COG0649	NAD binding
FA582_RS12150	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA582_RS12155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA582_RS12180	COG2226	methyltransferase
FA582_RS12185	COG1169	isochorismate synthase
FA582_RS12195	COG0738	Major facilitator superfamily
FA582_RS12200	COG4552	Acetyltransferase involved in intracellular survival and related
FA582_RS12225	COG1070	Carbohydrate kinase
FA582_RS12235	COG2755	lipolytic protein G-D-S-L family
FA582_RS12235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FA582_RS12240	COG3590	peptidase
FA582_RS12245	COG1051	belongs to the nudix hydrolase family
FA582_RS12250	COG1131	(ABC) transporter
FA582_RS12270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FA582_RS12275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA582_RS12275	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA582_RS12290	COG1061	Type III restriction enzyme res subunit
FA582_RS12295	COG0745	RESPONSE REGULATOR receiver
FA582_RS12300	COG2205	protein histidine kinase activity
FA582_RS12305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FA582_RS12310	COG0488	(ABC) transporter
FA582_RS12320	COG0438	transferase activity, transferring glycosyl groups
FA582_RS12335	COG3973	AAA domain
FA582_RS12335	COG3973	AAA domain
FA582_RS12340	COG0463	Glycosyl transferase, family 2
FA582_RS12375	COG0459	protein refolding
FA582_RS12380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FA582_RS12405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FA582_RS12425	COG0725	ABC transporter, periplasmic molybdate-binding protein
FA582_RS12440	COG1960	acyl-CoA dehydrogenase activity
FA582_RS12465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FA582_RS12470	COG1653	transport
FA582_RS12475	COG1175	transmembrane transport
FA582_RS12480	COG0395	ABC-type sugar transport system, permease component
FA582_RS12495	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FA582_RS12565	COG1302	Protein conserved in bacteria
FA582_RS12570	COG1595	DNA-templated transcription, initiation
FA582_RS12580	COG0798	PFAM Bile acid sodium symporter
FA582_RS12595	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FA582_RS12600	COG0789	Transcriptional regulator
FA582_RS12610	COG0010	Belongs to the arginase family
FA582_RS12615	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FA582_RS12620	COG3586	endonuclease activity
FA582_RS12630	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FA582_RS12640	COG4974	Belongs to the 'phage' integrase family
FA582_RS12675	COG1396	sequence-specific DNA binding
FA582_RS12710	COG1652	LysM domain
FA582_RS12725	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FA582_RS12745	COG3833	ABC-type maltose transport systems, permease component
FA582_RS12750	COG1175	transmembrane transport
FA582_RS12760	COG3842	ATPase activity
FA582_RS12780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA582_RS12785	COG0215	cysteine-tRNA ligase activity
FA582_RS12800	COG0706	membrane insertase activity
FA582_RS12810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FA582_RS12820	COG3764	Sortase (surface protein transpeptidase)
FA582_RS12830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FA582_RS12840	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FA582_RS12845	COG1329	Transcriptional regulator
FA582_RS12860	COG5002	protein histidine kinase activity
FA582_RS12870	COG0588	phosphoglycerate mutase activity
FA582_RS12880	COG0297	glycogen (starch) synthase activity
FA582_RS12900	COG1490	D-aminoacyl-tRNA deacylase activity
FA582_RS12920	COG3485	protocatechuate 3,4-dioxygenase
FA582_RS12930	COG0745	RESPONSE REGULATOR receiver
FA582_RS12935	COG0456	acetyltransferase
FA582_RS12985	COG4176	ABC-type proline glycine betaine transport system permease component
FA582_RS13065	COG2353	YceI-like domain
FA582_RS13070	COG0656	L-ascorbic acid biosynthetic process
FA582_RS13080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FA582_RS13080	COG0512	Glutamine amidotransferase of anthranilate synthase
FA582_RS13090	COG1252	NADH dehydrogenase
FA582_RS13095	COG0584	glycerophosphoryl diester phosphodiesterase
FA582_RS13105	COG1796	DNA polymerase
FA582_RS13105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FA582_RS13135	COG3842	ATPase activity
FA582_RS13160	COG0129	dihydroxy-acid dehydratase activity
FA582_RS13165	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FA582_RS13190	COG0728	peptidoglycan biosynthetic process
FA582_RS13225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FA582_RS13240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FA582_RS13260	COG0402	S-adenosylhomocysteine deaminase activity
FA582_RS13265	COG0366	Alpha amylase catalytic
FA582_RS13270	COG3265	gluconokinase activity
FA582_RS13275	COG2610	gluconate transmembrane transporter activity
FA582_RS13280	COG1739	Uncharacterized protein family UPF0029
FA582_RS13300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FA582_RS13385	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA582_RS13385	COG2247	cell wall binding repeat
FA582_RS13405	COG0798	PFAM Bile acid sodium symporter
FA582_RS13420	COG0590	tRNA wobble adenosine to inosine editing
FA582_RS13425	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FA582_RS13430	COG0436	Aminotransferase
FA582_RS13445	COG0242	peptide deformylase activity
FA582_RS13455	COG0477	Major facilitator Superfamily
FA582_RS13460	COG0436	Aminotransferase
FA582_RS13465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FA582_RS13475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA582_RS13480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA582_RS13495	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FA582_RS13510	COG1316	TRANSCRIPTIONal
FA582_RS13515	COG1278	Cold shock
FA582_RS13530	COG1045	serine acetyltransferase
FA582_RS13540	COG2181	nitrate reductase activity
FA582_RS13540	COG0247	lactate metabolic process
FA582_RS13545	COG0717	Belongs to the dCTP deaminase family
FA582_RS13555	COG1324	tolerance protein
FA582_RS13560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FA582_RS13565	COG0318	PFAM AMP-dependent synthetase and ligase
FA582_RS13570	COG1028	Short-chain dehydrogenase reductase Sdr
FA582_RS13595	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FA582_RS13600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FA582_RS13625	COG2801	Transposase and inactivated derivatives
FA582_RS13665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA582_RS13675	COG0747	negative chemotaxis
FA582_RS13685	COG1960	acyl-CoA dehydrogenase activity
FA582_RS13745	COG0508	dehydrogenase complex catalyzes the overall conversion of
FA582_RS13750	COG0022	dehydrogenase e1 component
FA582_RS13760	COG1950	PFAM Membrane protein of
FA582_RS13765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA582_RS13825	COG1132	(ABC) transporter
FA582_RS13845	COG0745	RESPONSE REGULATOR receiver
FA582_RS13850	COG2205	protein histidine kinase activity
FA582_RS13875	COG3842	ATPase activity
FA582_RS13915	COG1086	Polysaccharide biosynthesis protein
FA582_RS13920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA582_RS13925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FA582_RS13935	COG0438	transferase activity, transferring glycosyl groups
FA582_RS13960	COG0489	protein tyrosine kinase activity
FA582_RS13975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FA582_RS13980	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FA582_RS14010	COG2205	protein histidine kinase activity
FA582_RS14035	COG0471	metal ion transport
FA582_RS14035	COG3273	potassium ion transport
FA582_RS14135	COG3851	Histidine kinase
FA582_RS14140	COG2197	response regulator
FA582_RS14145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FA582_RS14150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FA582_RS14155	COG2171	N-acyltransferase activity
FA582_RS14160	COG0436	Aminotransferase
FA582_RS14195	COG0604	alcohol dehydrogenase
FA582_RS14195	COG3321	synthase
FA582_RS14235	COG0508	dehydrogenase complex catalyzes the overall conversion of
FA582_RS14255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FA582_RS14275	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FA582_RS14280	COG1414	Transcriptional regulator
FA582_RS14285	COG4941	Belongs to the sigma-70 factor family
FA582_RS14290	COG3795	YCII-related domain
FA582_RS14305	COG5598	trimethylamine methyltransferase
FA582_RS14310	COG1414	Transcriptional regulator
FA582_RS14315	COG5012	cobalamin binding
FA582_RS14355	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FA582_RS14360	COG1074	ATP-dependent DNA helicase activity
FA582_RS14375	COG4591	ABC-type transport system involved in lipoprotein release permease component
FA582_RS14380	COG1136	(ABC) transporter
FA582_RS14380	COG0577	efflux transmembrane transporter activity
FA582_RS14385	COG2197	response regulator
FA582_RS14390	COG4585	Histidine kinase
FA582_RS14395	COG1228	amidohydrolase
FA582_RS14400	COG0402	S-adenosylhomocysteine deaminase activity
FA582_RS14410	COG0442	prolyl-tRNA aminoacylation
FA582_RS14425	COG3314	Sporulation integral membrane protein YlbJ
FA582_RS14430	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FA582_RS14455	COG0058	SHG alpha-glucan phosphorylase activity
FA582_RS14495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FA582_RS14500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA582_RS14530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FA582_RS14530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FA582_RS14540	COG0549	Belongs to the carbamate kinase family
FA582_RS14600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FA582_RS14605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FA582_RS14610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FA582_RS14615	COG0339	signal peptide processing
FA582_RS14635	COG2226	methyltransferase
FA582_RS14645	COG1846	Transcriptional regulator
FA582_RS14650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA582_RS14690	COG2197	response regulator
FA582_RS14700	COG1846	Transcriptional regulator
FA582_RS14720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FA582_RS14730	COG2814	Major facilitator Superfamily
FA582_RS14755	COG1268	BioY protein
FA582_RS14785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA582_RS14790	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA582_RS14795	COG1120	ATPase activity
FA582_RS14810	COG2409	Drug exporters of the RND superfamily
FA582_RS14820	COG0315	cyclic pyranopterin monophosphate synthase activity
FA582_RS14820	COG0521	Mo-molybdopterin cofactor biosynthetic process
FA582_RS14825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FA582_RS14835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA582_RS14840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FA582_RS14845	COG1802	Transcriptional regulator
FA582_RS14850	COG4145	pantothenate transmembrane transporter activity
FA582_RS14865	COG0746	molybdenum cofactor guanylyltransferase activity
FA582_RS14885	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FA582_RS14890	COG1140	nitrate reductase beta subunit
FA582_RS14940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FA582_RS14960	COG2814	Major facilitator Superfamily
FA582_RS14975	COG3383	formate dehydrogenase (NAD+) activity
FA582_RS15010	COG1914	H( )-stimulated, divalent metal cation uptake system
FA582_RS15020	COG0730	response to heat
FA582_RS15025	COG1959	2 iron, 2 sulfur cluster binding
FA582_RS15030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FA582_RS15040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FA582_RS15055	COG3275	phosphorelay sensor kinase activity
FA582_RS15070	COG0477	Major facilitator Superfamily
FA582_RS15090	COG0667	Aldo Keto reductase
FA582_RS15110	COG0395	ABC-type sugar transport system, permease component
FA582_RS15115	COG1175	transmembrane transport
FA582_RS15125	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FA582_RS15140	COG0471	metal ion transport
FA582_RS15155	COG1960	acyl-CoA dehydrogenase activity
FA582_RS15160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FA582_RS15165	COG0745	RESPONSE REGULATOR receiver
FA582_RS15175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FA582_RS15205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA582_RS15210	COG0738	Major facilitator superfamily
FA582_RS15230	COG1230	cation diffusion facilitator family transporter
FA582_RS15260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FA582_RS15265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA582_RS15270	COG1120	ATPase activity
FA582_RS15275	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FA582_RS15280	COG1492	cobalamin metabolic process
FA582_RS15290	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FA582_RS15300	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FA582_RS15305	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FA582_RS15325	COG0415	Belongs to the DNA photolyase family
FA582_RS15330	COG0686	Belongs to the AlaDH PNT family
FA582_RS15345	COG2311	Membrane
FA582_RS15365	COG4067	protein conserved in archaea
FA582_RS15365	COG0189	ligase activity
FA582_RS15370	COG0569	domain protein
FA582_RS15370	COG0189	ligase activity
FA582_RS15375	COG3177	Filamentation induced by cAMP protein fic
FA582_RS15405	COG0175	sulfate reduction
FA582_RS15415	COG1131	(ABC) transporter
FA582_RS15475	COG4106	trans-aconitate 2-methyltransferase activity
FA582_RS15480	COG2318	DinB family
FA582_RS15485	COG1063	alcohol dehydrogenase
FA582_RS15540	COG0372	Belongs to the citrate synthase family
FA582_RS15555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA582_RS15590	COG0366	Alpha amylase catalytic
FA582_RS15615	COG1902	pentaerythritol trinitrate reductase activity
FA582_RS15615	COG0446	pyridine nucleotide-disulphide oxidoreductase
FA582_RS15660	COG0640	Transcriptional regulator
FA582_RS15670	COG2318	DinB family
FA582_RS15675	COG2318	DinB family
FA582_RS15700	COG1621	beta-fructofuranosidase activity
FA582_RS15735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FA582_RS15740	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FA582_RS15745	COG2080	2 iron, 2 sulfur cluster binding
FA582_RS15790	COG5006	permease, DMT superfamily
FA582_RS15795	COG0583	DNA-binding transcription factor activity
FA582_RS15805	COG0386	Belongs to the glutathione peroxidase family
FA582_RS15810	COG1869	D-ribose catabolic process
FA582_RS15820	COG1879	ABC-type sugar transport system periplasmic component
FA582_RS15825	COG1172	Belongs to the binding-protein-dependent transport system permease family
FA582_RS15830	COG1129	ABC transporter
FA582_RS15835	COG1609	Transcriptional regulator
FA582_RS15840	COG0456	acetyltransferase
FA582_RS15915	COG3795	YCII-related domain
FA582_RS15920	COG4941	Belongs to the sigma-70 factor family
FA582_RS15930	COG0740	serine-type endopeptidase activity
FA582_RS15935	COG0740	serine-type endopeptidase activity
FA582_RS15940	COG3634	alkyl hydroperoxide reductase activity
FA582_RS15955	COG0586	Pfam SNARE associated Golgi protein
FA582_RS15985	COG0693	protein deglycase activity
FA582_RS16015	COG1320	monovalent cation:proton antiporter activity
FA582_RS16020	COG2212	antiporter activity
FA582_RS16030	COG0651	ATP synthesis coupled electron transport
FA582_RS16035	COG1006	Multisubunit Na H antiporter MnhC subunit
FA582_RS16040	COG2111	Na H antiporter
FA582_RS16040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA582_RS16045	COG0359	binds to the 23S rRNA
FA582_RS16050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FA582_RS16055	COG0629	single-stranded DNA binding
FA582_RS16060	COG0360	Binds together with S18 to 16S ribosomal RNA
FA582_RS16070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FA582_RS16070	COG2755	lipolytic protein G-D-S-L family
FA582_RS16075	COG2755	lipolytic protein G-D-S-L family
FA582_RS16075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FA582_RS16085	COG1216	Glycosyl transferase, family 2
FA582_RS16085	COG0438	transferase activity, transferring glycosyl groups
FA582_RS16095	COG1216	Glycosyl transferase, family 2
FA582_RS16115	COG1134	teichoic acid transport
FA582_RS16160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FA582_RS16170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FA582_RS16170	COG2755	lipolytic protein G-D-S-L family
FA582_RS16180	COG0617	tRNA 3'-terminal CCA addition
FA582_RS16195	COG2815	serine threonine protein kinase
FA582_RS16195	COG0515	serine threonine protein kinase
FA582_RS16200	COG1595	DNA-templated transcription, initiation
FA582_RS16210	COG0492	ferredoxin-NADP+ reductase activity
FA582_RS16215	COG3118	belongs to the thioredoxin family
FA582_RS16220	COG1192	Involved in chromosome partitioning
FA582_RS16240	COG0706	membrane insertase activity
FA582_RS16245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FA582_RS16250	COG0594	ribonuclease P activity
FA582_RS16255	COG0230	Belongs to the bacterial ribosomal protein bL34 family