locus-tag	class	description
AL485_RS00010	COG0309	Hydrogenase expression formation protein (HypE)
AL485_RS00015	COG0409	Hydrogenase expression formation protein
AL485_RS00020	COG0298	carbon dioxide binding
AL485_RS00025	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AL485_RS00030	COG0375	protein maturation
AL485_RS00040	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL485_RS00045	COG0651	ATP synthesis coupled electron transport
AL485_RS00050	COG0650	Formate hydrogenlyase subunit 4
AL485_RS00055	COG3261	NADH dehydrogenase
AL485_RS00055	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AL485_RS00060	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL485_RS00065	COG3260	NADH ubiquinone oxidoreductase 20
AL485_RS00075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL485_RS00080	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL485_RS00085	COG3383	formate dehydrogenase (NAD+) activity
AL485_RS00090	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AL485_RS00095	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AL485_RS00110	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS00115	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL485_RS00120	COG1802	Transcriptional regulator
AL485_RS00155	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS00160	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AL485_RS00175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL485_RS00180	COG0076	glutamate decarboxylase activity
AL485_RS00205	COG0583	DNA-binding transcription factor activity
AL485_RS00210	COG4993	Dehydrogenase
AL485_RS00230	COG3284	Transcriptional regulator
AL485_RS00240	COG1064	alcohol dehydrogenase
AL485_RS00255	COG1522	sequence-specific DNA binding
AL485_RS00280	COG0583	DNA-binding transcription factor activity
AL485_RS00285	COG2814	Major facilitator Superfamily
AL485_RS00300	COG0673	inositol 2-dehydrogenase activity
AL485_RS00315	COG4558	Periplasmic binding protein
AL485_RS00330	COG2862	Uncharacterized protein family, UPF0114
AL485_RS00350	COG0371	Dehydrogenase
AL485_RS00370	COG2814	Major facilitator Superfamily
AL485_RS00380	COG2814	Major facilitator Superfamily
AL485_RS00390	COG0583	DNA-binding transcription factor activity
AL485_RS00395	COG2079	MmgE PrpD family protein
AL485_RS00400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL485_RS00410	COG0765	amino acid transport
AL485_RS00415	COG1126	abc transporter atp-binding protein
AL485_RS00430	COG0768	penicillin binding
AL485_RS00450	COG4608	Belongs to the ABC transporter superfamily
AL485_RS00455	COG0444	Belongs to the ABC transporter superfamily
AL485_RS00460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL485_RS00465	COG0601	transmembrane transport
AL485_RS00470	COG0747	negative chemotaxis
AL485_RS00475	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AL485_RS00490	COG2814	Major facilitator Superfamily
AL485_RS00550	COG0596	Alpha beta hydrolase
AL485_RS00585	COG2723	6-phospho-beta-galactosidase activity
AL485_RS00590	COG1263	PTS System
AL485_RS00590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS00590	COG2190	(PTS) system
AL485_RS00595	COG2140	Oxalate decarboxylase
AL485_RS00600	COG2010	Cytochrome c
AL485_RS00600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL485_RS00615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL485_RS00635	COG0583	DNA-binding transcription factor activity
AL485_RS00640	COG2010	Cytochrome c
AL485_RS00640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL485_RS00645	COG2080	2 iron, 2 sulfur cluster binding
AL485_RS00650	COG1846	Transcriptional regulator
AL485_RS00655	COG2309	aminopeptidase activity
AL485_RS00660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL485_RS00665	COG0596	Alpha beta hydrolase
AL485_RS00670	COG3473	Maleate cis-trans isomerase
AL485_RS00675	COG1335	isochorismatase
AL485_RS00680	COG2271	Major facilitator Superfamily
AL485_RS00685	COG0339	signal peptide processing
AL485_RS00695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL485_RS00705	COG0402	S-adenosylhomocysteine deaminase activity
AL485_RS00710	COG1940	carbohydrate kinase activity
AL485_RS00715	COG2182	Extracellular solute-binding protein
AL485_RS00730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL485_RS00735	COG3842	ATPase activity
AL485_RS00740	COG1595	DNA-templated transcription, initiation
AL485_RS00745	COG3712	iron ion homeostasis
AL485_RS00750	COG4772	TonB-dependent receptor
AL485_RS00755	COG0477	Major facilitator Superfamily
AL485_RS00765	COG4221	oxidoreductase activity
AL485_RS00770	COG1742	UPF0060 membrane protein
AL485_RS00785	COG0477	Major facilitator Superfamily
AL485_RS00795	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL485_RS00800	COG1940	carbohydrate kinase activity
AL485_RS00805	COG0583	DNA-binding transcription factor activity
AL485_RS00810	COG2814	Major facilitator Superfamily
AL485_RS00825	COG2378	regulation of single-species biofilm formation
AL485_RS00830	COG0114	fumarate hydratase activity
AL485_RS00845	COG5339	Protein conserved in bacteria
AL485_RS00850	COG5339	Protein conserved in bacteria
AL485_RS00855	COG5339	Protein conserved in bacteria
AL485_RS00865	COG0583	DNA-binding transcription factor activity
AL485_RS00875	COG2814	Major facilitator Superfamily
AL485_RS00890	COG1609	Transcriptional regulator
AL485_RS00895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS00895	COG1263	PTS System
AL485_RS00900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL485_RS00910	COG0494	nUDIX hydrolase
AL485_RS00915	COG1349	DNA-binding transcription factor activity
AL485_RS00920	COG0205	6-phosphofructokinase activity
AL485_RS00945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL485_RS00950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL485_RS00955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL485_RS00960	COG0385	Bile acid
AL485_RS00965	COG0673	inositol 2-dehydrogenase activity
AL485_RS00975	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS00980	COG1129	ABC transporter
AL485_RS00985	COG1879	ABC-type sugar transport system periplasmic component
AL485_RS00990	COG1069	ribulokinase activity
AL485_RS00995	COG2160	L-arabinose isomerase activity
AL485_RS01005	COG4657	Part of a membrane complex involved in electron transport
AL485_RS01010	COG2878	Part of a membrane complex involved in electron transport
AL485_RS01015	COG4656	Part of a membrane complex involved in electron transport
AL485_RS01020	COG2207	Transcriptional regulator
AL485_RS01020	COG3708	Transcriptional regulator
AL485_RS01030	COG4659	FMN binding
AL485_RS01040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL485_RS01045	COG3104	oligopeptide transport
AL485_RS01050	COG1505	serine-type exopeptidase activity
AL485_RS01055	COG1396	sequence-specific DNA binding
AL485_RS01060	COG3135	benzoate transporter
AL485_RS01090	COG1418	mRNA catabolic process
AL485_RS01110	COG0625	glutathione transferase activity
AL485_RS01120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL485_RS01125	COG0259	pyridoxamine-phosphate oxidase activity
AL485_RS01130	COG3895	Periplasmic Protein
AL485_RS01135	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL485_RS01140	COG3133	Outer membrane lipoprotein
AL485_RS01145	COG1846	Transcriptional regulator
AL485_RS01155	COG1566	PFAM secretion protein HlyD family protein
AL485_RS01160	COG1289	transmembrane transporter activity
AL485_RS01170	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AL485_RS01175	COG4989	oxidoreductase activity
AL485_RS01180	COG3313	Fe-S protein
AL485_RS01185	COG0583	DNA-binding transcription factor activity
AL485_RS01190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL485_RS01195	COG2194	sulfuric ester hydrolase activity
AL485_RS01200	COG1309	transcriptional regulator
AL485_RS01205	COG1902	pentaerythritol trinitrate reductase activity
AL485_RS01210	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AL485_RS01215	COG0346	lactoylglutathione lyase activity
AL485_RS01225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL485_RS01230	COG0791	NLP P60 protein
AL485_RS01245	COG1609	Transcriptional regulator
AL485_RS01250	COG0583	DNA-binding transcription factor activity
AL485_RS01255	COG2814	Major facilitator Superfamily
AL485_RS01260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL485_RS01270	COG0307	riboflavin synthase, alpha
AL485_RS01275	COG0534	Mate efflux family protein
AL485_RS01300	COG0469	pyruvate kinase activity
AL485_RS01310	COG1388	LysM domain
AL485_RS01310	COG1376	ErfK ybiS ycfS ynhG family protein
AL485_RS01315	COG2166	iron-sulfur cluster assembly
AL485_RS01320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL485_RS01325	COG0719	Fe-S assembly protein
AL485_RS01330	COG0396	ATPase activity
AL485_RS01335	COG0719	Fe-S assembly protein
AL485_RS01340	COG0316	Belongs to the HesB IscA family
AL485_RS01350	COG2050	protein possibly involved in aromatic compounds catabolism
AL485_RS01355	COG0247	lactate metabolic process
AL485_RS01355	COG0277	FAD linked oxidase domain protein
AL485_RS01360	COG0628	permease
AL485_RS01370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL485_RS01370	COG0574	Belongs to the PEP-utilizing enzyme family
AL485_RS01380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL485_RS01385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL485_RS01390	COG0386	Belongs to the glutathione peroxidase family
AL485_RS01405	COG3720	iron ion transport
AL485_RS01410	COG4558	Periplasmic binding protein
AL485_RS01415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL485_RS01420	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL485_RS01435	COG0095	Lipoate-protein ligase
AL485_RS01440	COG0791	NLP P60 protein
AL485_RS01445	COG2076	Multidrug Resistance protein
AL485_RS01450	COG2076	Multidrug Resistance protein
AL485_RS01455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL485_RS01460	COG0726	polysaccharide deacetylase
AL485_RS01465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL485_RS01465	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL485_RS01470	COG1215	transferase activity, transferring glycosyl groups
AL485_RS01475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL485_RS01480	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AL485_RS01485	COG0386	Belongs to the glutathione peroxidase family
AL485_RS01490	COG4139	cobalamin transport
AL485_RS01500	COG0776	regulation of translation
AL485_RS01510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL485_RS01515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL485_RS01520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL485_RS01530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL485_RS01560	COG0814	amino acid
AL485_RS01590	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL485_RS01595	COG1121	(ABC) transporter
AL485_RS01600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL485_RS01605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL485_RS01615	COG3001	Fructosamine kinase
AL485_RS01630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL485_RS01635	COG1988	membrane-bound metal-dependent
AL485_RS01640	COG1823	symporter activity
AL485_RS01655	COG2188	Transcriptional regulator
AL485_RS01665	COG2814	Major facilitator Superfamily
AL485_RS01670	COG0501	Belongs to the peptidase M48B family
AL485_RS01680	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AL485_RS01685	COG1956	GAF domain-containing protein
AL485_RS01690	COG2995	paraquat-inducible protein a
AL485_RS01695	COG3008	intermembrane lipid transfer
AL485_RS01700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL485_RS01700	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AL485_RS01755	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AL485_RS01760	COG3493	citrate carrier protein
AL485_RS01765	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AL485_RS01785	COG0477	Major facilitator Superfamily
AL485_RS01790	COG2211	Major facilitator Superfamily
AL485_RS01810	COG0402	S-adenosylhomocysteine deaminase activity
AL485_RS01820	COG1228	amidohydrolase
AL485_RS01835	COG1605	Chorismate mutase
AL485_RS01870	COG0531	amino acid
AL485_RS01880	COG0174	glutamine synthetase
AL485_RS01885	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL485_RS01890	COG1917	Cupin 2, conserved barrel domain protein
AL485_RS01890	COG1396	sequence-specific DNA binding
AL485_RS01895	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS01900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL485_RS01905	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS01910	COG0589	response to stress
AL485_RS01915	COG1335	isochorismatase
AL485_RS01920	COG1278	Cold shock
AL485_RS01940	COG0673	inositol 2-dehydrogenase activity
AL485_RS01975	COG0628	permease
AL485_RS01990	COG0583	DNA-binding transcription factor activity
AL485_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS02010	COG0582	viral genome integration into host DNA
AL485_RS02030	COG0538	isocitrate dehydrogenase activity
AL485_RS02035	COG1187	pseudouridine synthase activity
AL485_RS02050	COG0482	sulfurtransferase activity
AL485_RS02055	COG2915	High frequency lysogenization protein hflD homolog
AL485_RS02060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL485_RS02095	COG0745	RESPONSE REGULATOR receiver
AL485_RS02105	COG2850	peptidyl-arginine hydroxylation
AL485_RS02110	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL485_RS02115	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL485_RS02120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS02120	COG1263	PTS System
AL485_RS02125	COG1486	melibiose metabolic process
AL485_RS02145	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL485_RS02155	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL485_RS02170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL485_RS02175	COG3706	GGDEF domain
AL485_RS02180	COG4702	Belongs to the UPF0303 family
AL485_RS02185	COG0659	secondary active sulfate transmembrane transporter activity
AL485_RS02190	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL485_RS02205	COG2890	protein-(glutamine-N5) methyltransferase activity
AL485_RS02210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL485_RS02215	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL485_RS02220	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL485_RS02225	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL485_RS02230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL485_RS02240	COG0193	aminoacyl-tRNA hydrolase activity
AL485_RS02245	COG0659	secondary active sulfate transmembrane transporter activity
AL485_RS02250	COG0012	GTP binding
AL485_RS02255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL485_RS02265	COG0740	serine-type endopeptidase activity
AL485_RS02280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL485_RS02285	COG2313	pseudouridylate synthase activity
AL485_RS02290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL485_RS02295	COG0531	amino acid
AL485_RS02305	COG2731	YhcH YjgK YiaL family protein
AL485_RS02310	COG3250	beta-galactosidase activity
AL485_RS02315	COG1609	Transcriptional regulator
AL485_RS02325	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AL485_RS02325	COG3408	Glycogen debranching enzyme
AL485_RS02330	COG0589	response to stress
AL485_RS02335	COG1858	cytochrome C peroxidase
AL485_RS02365	COG1464	Belongs to the NlpA lipoprotein family
AL485_RS02385	COG0579	oxidoreductase
AL485_RS02395	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS02400	COG1129	ABC transporter
AL485_RS02415	COG3290	protein histidine kinase activity
AL485_RS02420	COG4565	transcriptional regulatory protein
AL485_RS02455	COG3655	Transcriptional regulator
AL485_RS02465	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL485_RS02580	COG4725	Belongs to the MT-A70-like family
AL485_RS02720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL485_RS02725	COG2135	peptidase activity
AL485_RS02745	COG0582	viral genome integration into host DNA
AL485_RS02760	COG1276	copper resistance
AL485_RS02765	COG2372	response to copper ion
AL485_RS02770	COG1528	Iron-storage protein
AL485_RS02790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL485_RS02795	COG1770	oligopeptidase
AL485_RS02800	COG2979	Protein of unknown function (DUF533)
AL485_RS02805	COG3381	protein complex oligomerization
AL485_RS02810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL485_RS02815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL485_RS02835	COG3708	Transcriptional regulator
AL485_RS02835	COG2207	Transcriptional regulator
AL485_RS02840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS02855	COG3134	Outer membrane lipoprotein
AL485_RS02860	COG1252	NADH dehydrogenase
AL485_RS02865	COG3150	esterase
AL485_RS02875	COG0510	thiamine kinase activity
AL485_RS02880	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AL485_RS02885	COG5633	Lipoprotein
AL485_RS02890	COG0537	adenosine 5'-monophosphoramidase activity
AL485_RS02895	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL485_RS02900	COG1733	regulation of RNA biosynthetic process
AL485_RS02905	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS02915	COG0583	DNA-binding transcription factor activity
AL485_RS02925	COG1914	H( )-stimulated, divalent metal cation uptake system
AL485_RS02930	COG1321	iron dependent repressor
AL485_RS02940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS02940	COG1263	PTS System
AL485_RS02945	COG0084	hydrolase, TatD family'
AL485_RS02950	COG0470	DNA polymerase III
AL485_RS02955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL485_RS02960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL485_RS02965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL485_RS02970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL485_RS02975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL485_RS02990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL485_RS02995	COG0416	fatty acid biosynthetic process
AL485_RS03000	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL485_RS03015	COG0564	pseudouridine synthase activity
AL485_RS03020	COG1530	ribonuclease E activity
AL485_RS03025	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL485_RS03030	COG0418	dihydroorotase activity
AL485_RS03070	COG0628	permease
AL485_RS03075	COG3038	cytochrome b561
AL485_RS03080	COG2353	YceI-like domain
AL485_RS03085	COG1054	Belongs to the UPF0176 family
AL485_RS03090	COG1902	pentaerythritol trinitrate reductase activity
AL485_RS03100	COG1560	Kdo2-lipid A biosynthetic process
AL485_RS03110	COG2814	Major facilitator Superfamily
AL485_RS03120	COG0346	lactoylglutathione lyase activity
AL485_RS03135	COG0640	Transcriptional regulator
AL485_RS03145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL485_RS03160	COG5645	(Lipo)protein
AL485_RS03165	COG2943	transferase activity, transferring hexosyl groups
AL485_RS03170	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AL485_RS03200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS03220	COG2194	sulfuric ester hydrolase activity
AL485_RS03225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL485_RS03230	COG1486	melibiose metabolic process
AL485_RS03235	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL485_RS03240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL485_RS03280	COG0322	excinuclease ABC activity
AL485_RS03285	COG2197	response regulator
AL485_RS03295	COG3136	membrane protein required for alginate biosynthesis
AL485_RS03340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL485_RS03345	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS03350	COG0531	amino acid
AL485_RS03365	COG2197	response regulator
AL485_RS03370	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL485_RS03375	COG0183	Belongs to the thiolase family
AL485_RS03380	COG0156	8-amino-7-oxononanoate synthase activity
AL485_RS03385	COG2814	Major facilitator Superfamily
AL485_RS03390	COG1024	Enoyl-CoA hydratase
AL485_RS03400	COG2271	Major facilitator Superfamily
AL485_RS03405	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL485_RS03415	COG3064	Membrane
AL485_RS03425	COG0322	excinuclease ABC activity
AL485_RS03450	COG1113	amino acid transport
AL485_RS03455	COG1309	transcriptional regulator
AL485_RS03460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL485_RS03465	COG1335	isochorismatase
AL485_RS03470	COG0251	oxidation-reduction process
AL485_RS03475	COG2267	carboxylic ester hydrolase activity
AL485_RS03480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL485_RS03485	COG2233	PERMEase
AL485_RS03510	COG1280	lysine exporter protein (LysE YggA)
AL485_RS03515	COG0655	NAD(P)H dehydrogenase (quinone) activity
AL485_RS03525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL485_RS03555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL485_RS03565	COG0670	Belongs to the BI1 family
AL485_RS03570	COG2920	part of a sulfur-relay system
AL485_RS03575	COG1254	Belongs to the acylphosphatase family
AL485_RS03580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL485_RS03585	COG3785	DNA binding
AL485_RS03590	COG1832	CoA-binding protein
AL485_RS03600	COG1803	Methylglyoxal synthase
AL485_RS03605	COG0210	DNA helicase
AL485_RS03610	COG3304	Inner membrane component domain
AL485_RS03615	COG1289	transmembrane transporter activity
AL485_RS03630	COG3070	regulator of competence-specific genes
AL485_RS03635	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
AL485_RS03645	COG3120	sequence-specific DNA binding
AL485_RS03650	COG1067	ATP-dependent peptidase activity
AL485_RS03655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL485_RS03665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL485_RS03670	COG3130	regulation of translation
AL485_RS03675	COG3009	Protein conserved in bacteria
AL485_RS03680	COG3008	intermembrane lipid transfer
AL485_RS03680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL485_RS03685	COG2995	paraquat-inducible protein a
AL485_RS03690	COG0488	(ABC) transporter
AL485_RS03695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL485_RS03695	COG0116	Belongs to the methyltransferase superfamily
AL485_RS03700	COG3217	Mosc domain protein beta barrel domain protein
AL485_RS03700	COG0633	Ferredoxin
AL485_RS03710	COG0167	dihydroorotate dehydrogenase activity
AL485_RS03715	COG0431	NADPH-dependent FMN reductase
AL485_RS03720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL485_RS03725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL485_RS03730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL485_RS03740	COG0308	aminopeptidase N
AL485_RS03745	COG3706	GGDEF domain
AL485_RS03750	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL485_RS03755	COG0017	Asparaginyl-tRNA synthetase
AL485_RS03765	COG1448	Aminotransferase
AL485_RS03770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL485_RS03775	COG3108	Peptidase M15
AL485_RS03780	COG2989	Protein conserved in bacteria
AL485_RS03785	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL485_RS03795	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AL485_RS03800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL485_RS03805	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL485_RS03810	COG3173	Aminoglycoside phosphotransferase
AL485_RS03815	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL485_RS03820	COG2835	tetraacyldisaccharide 4'-kinase activity
AL485_RS03825	COG3214	Protein conserved in bacteria
AL485_RS03830	COG1278	Cold shock
AL485_RS03840	COG5383	Protein conserved in bacteria
AL485_RS03845	COG1663	tetraacyldisaccharide 4'-kinase activity
AL485_RS03855	COG0658	competence protein
AL485_RS03855	COG2333	competence protein COMEC
AL485_RS03860	COG0776	regulation of translation
AL485_RS03865	COG0539	negative regulation of cytoplasmic translation
AL485_RS03870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL485_RS03875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL485_RS03880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL485_RS03885	COG0252	asparaginase activity
AL485_RS03890	COG1944	ATP diphosphatase activity
AL485_RS03895	COG2116	formate transmembrane transporter activity
AL485_RS03900	COG1882	Formate acetyltransferase
AL485_RS03905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL485_RS03915	COG3381	protein complex oligomerization
AL485_RS03920	COG3302	dmso reductase anchor subunit
AL485_RS03925	COG0437	4 iron, 4 sulfur cluster binding
AL485_RS03930	COG0243	molybdopterin cofactor binding
AL485_RS03935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL485_RS03940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL485_RS03945	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL485_RS03950	COG1674	ftsk spoiiie
AL485_RS03950	COG3107	peptidoglycan biosynthetic process
AL485_RS03960	COG0492	ferredoxin-NADP+ reductase activity
AL485_RS03965	COG0583	DNA-binding transcription factor activity
AL485_RS03975	COG4988	ABC transporter
AL485_RS03980	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL485_RS03985	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL485_RS03990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL485_RS03995	COG0542	response to heat
AL485_RS04000	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL485_RS04005	COG1278	Cold shock
AL485_RS04015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS04020	COG2990	Protein conserved in bacteria
AL485_RS04025	COG3593	DNA synthesis involved in DNA repair
AL485_RS04030	COG2431	L-lysine efflux transmembrane transporter activity
AL485_RS04035	COG1151	hydroxylamine reductase activity
AL485_RS04040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL485_RS04045	COG0028	Belongs to the TPP enzyme family
AL485_RS04050	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL485_RS04060	COG0702	epimerase
AL485_RS04065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL485_RS04070	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL485_RS04075	COG3064	Membrane
AL485_RS04080	COG0393	Putative heavy-metal-binding
AL485_RS04090	COG1126	abc transporter atp-binding protein
AL485_RS04095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL485_RS04100	COG4215	(ABC) transporter
AL485_RS04105	COG4160	amino acid transport
AL485_RS04110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL485_RS04115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL485_RS04125	COG1177	transmembrane transport
AL485_RS04130	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL485_RS04135	COG3842	ATPase activity
AL485_RS04140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL485_RS04150	COG0189	ligase activity
AL485_RS04170	COG2985	domain, Protein
AL485_RS04170	COG0569	domain protein
AL485_RS04175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL485_RS04180	COG4574	serine-type endopeptidase inhibitor activity
AL485_RS04195	COG0671	phosphoesterase, PA-phosphatase related
AL485_RS04205	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AL485_RS04210	COG1349	DNA-binding transcription factor activity
AL485_RS04215	COG0814	amino acid
AL485_RS04220	COG1760	l-serine dehydratase
AL485_RS04225	COG1686	Belongs to the peptidase S11 family
AL485_RS04250	COG0625	glutathione transferase activity
AL485_RS04255	COG2133	pyrroloquinoline quinone binding
AL485_RS04265	COG0598	Magnesium transport protein CorA
AL485_RS04270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL485_RS04285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL485_RS04295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL485_RS04305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL485_RS04320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL485_RS04325	COG0107	imidazoleglycerol-phosphate synthase activity
AL485_RS04330	COG0140	phosphoribosyl-ATP diphosphatase activity
AL485_RS04330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL485_RS04335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL485_RS04350	COG0463	Glycosyl transferase, family 2
AL485_RS04365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL485_RS04375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL485_RS04415	COG0438	transferase activity, transferring glycosyl groups
AL485_RS04420	COG2244	polysaccharide biosynthetic process
AL485_RS04465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL485_RS04470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL485_RS04475	COG1253	flavin adenine dinucleotide binding
AL485_RS04480	COG3069	C4-dicarboxylate transmembrane transporter activity
AL485_RS04485	COG2982	Protein involved in outer membrane biogenesis
AL485_RS04490	COG0717	Belongs to the dCTP deaminase family
AL485_RS04495	COG0572	uridine kinase
AL485_RS04505	COG0489	protein tyrosine kinase activity
AL485_RS04510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL485_RS04510	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL485_RS04515	COG2814	Major facilitator Superfamily
AL485_RS04520	COG1380	Effector of murein hydrolase LrgA
AL485_RS04525	COG1346	cytolysis
AL485_RS04530	COG0295	cytidine deaminase activity
AL485_RS04535	COG0281	malic enzyme
AL485_RS04540	COG2949	membrane
AL485_RS04560	COG1609	Transcriptional regulator
AL485_RS04565	COG2311	Membrane
AL485_RS04570	COG0302	gtp cyclohydrolase
AL485_RS04575	COG0477	Major facilitator Superfamily
AL485_RS04580	COG0583	DNA-binding transcription factor activity
AL485_RS04610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL485_RS04615	COG0601	transmembrane transport
AL485_RS04620	COG0747	negative chemotaxis
AL485_RS04625	COG4172	Belongs to the ABC transporter superfamily
AL485_RS04640	COG0303	'Molybdopterin
AL485_RS04645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL485_RS04650	COG0488	(ABC) transporter
AL485_RS04660	COG0583	DNA-binding transcription factor activity
AL485_RS04665	COG0288	reversible hydration of carbon dioxide
AL485_RS04670	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AL485_RS04690	COG0640	Transcriptional regulator
AL485_RS04695	COG0625	glutathione transferase activity
AL485_RS04715	COG0579	oxidoreductase
AL485_RS04720	COG3708	Transcriptional regulator
AL485_RS04720	COG2207	Transcriptional regulator
AL485_RS04730	COG3188	usher protein
AL485_RS04735	COG3121	Chaperone
AL485_RS04745	COG2200	EAL domain
AL485_RS04755	COG0069	glutamate synthase activity
AL485_RS04760	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AL485_RS04765	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS04770	COG1309	transcriptional regulator
AL485_RS04775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL485_RS04790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL485_RS04795	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AL485_RS04800	COG0745	RESPONSE REGULATOR receiver
AL485_RS04805	COG5002	protein histidine kinase activity
AL485_RS04820	COG3188	usher protein
AL485_RS04860	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AL485_RS04865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL485_RS04870	COG1349	DNA-binding transcription factor activity
AL485_RS04875	COG2084	Dehydrogenase
AL485_RS04880	COG3395	kinase activity
AL485_RS04885	COG0235	Class ii aldolase
AL485_RS04890	COG3622	Belongs to the hyi family
AL485_RS04895	COG2610	gluconate transmembrane transporter activity
AL485_RS04910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL485_RS04915	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL485_RS04925	COG2731	YhcH YjgK YiaL family protein
AL485_RS04935	COG0783	Belongs to the Dps family
AL485_RS04940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL485_RS04950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL485_RS04955	COG0765	amino acid transport
AL485_RS04960	COG1126	abc transporter atp-binding protein
AL485_RS04965	COG0668	transmembrane transport
AL485_RS04995	COG3121	Chaperone
AL485_RS05000	COG3188	usher protein
AL485_RS05030	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AL485_RS05035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL485_RS05050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL485_RS05060	COG0477	Major facilitator Superfamily
AL485_RS05070	COG1280	lysine exporter protein (LysE YggA)
AL485_RS05075	COG0583	DNA-binding transcription factor activity
AL485_RS05080	COG2814	Major facilitator Superfamily
AL485_RS05085	COG0697	spore germination
AL485_RS05090	COG1522	sequence-specific DNA binding
AL485_RS05095	COG1199	ATP-dependent helicase activity
AL485_RS05120	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AL485_RS05145	COG0697	spore germination
AL485_RS05165	COG1174	glycine betaine transport
AL485_RS05170	COG1125	glycine betaine transport
AL485_RS05175	COG1174	glycine betaine transport
AL485_RS05180	COG1732	Glycine betaine
AL485_RS05190	COG1051	belongs to the nudix hydrolase family
AL485_RS05200	COG0583	DNA-binding transcription factor activity
AL485_RS05205	COG1335	isochorismatase
AL485_RS05215	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL485_RS05225	COG0625	glutathione transferase activity
AL485_RS05235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL485_RS05240	COG4221	oxidoreductase activity
AL485_RS05255	COG1683	Conserved Protein
AL485_RS05265	COG2897	thiosulfate sulfurtransferase activity
AL485_RS05270	COG0583	DNA-binding transcription factor activity
AL485_RS05275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL485_RS05290	COG3511	phospholipase C
AL485_RS05330	COG1802	Transcriptional regulator
AL485_RS05350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL485_RS05365	COG0840	transmembrane signaling receptor activity
AL485_RS05370	COG4807	Protein conserved in bacteria
AL485_RS05390	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL485_RS05400	COG1063	alcohol dehydrogenase
AL485_RS05405	COG1802	Transcriptional regulator
AL485_RS05410	COG2271	Major facilitator Superfamily
AL485_RS05420	COG0583	DNA-binding transcription factor activity
AL485_RS05430	COG2084	Dehydrogenase
AL485_RS05435	COG1335	isochorismatase
AL485_RS05455	COG0583	DNA-binding transcription factor activity
AL485_RS05465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL485_RS05470	COG2011	ABC-type metal ion transport system permease component
AL485_RS05475	COG1464	Belongs to the NlpA lipoprotein family
AL485_RS05480	COG1309	transcriptional regulator
AL485_RS05515	COG0366	Alpha amylase catalytic
AL485_RS05540	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL485_RS05545	COG1070	Carbohydrate kinase
AL485_RS05550	COG2814	Major facilitator Superfamily
AL485_RS05570	COG1192	Involved in chromosome partitioning
AL485_RS05585	COG1120	ATPase activity
AL485_RS05590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL485_RS05595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL485_RS05600	COG1472	Belongs to the glycosyl hydrolase 3 family
AL485_RS05610	COG0436	Aminotransferase
AL485_RS05620	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL485_RS05635	COG0277	FAD linked oxidase domain protein
AL485_RS05640	COG0840	transmembrane signaling receptor activity
AL485_RS05675	COG1464	Belongs to the NlpA lipoprotein family
AL485_RS05685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL485_RS05700	COG2354	Protein conserved in bacteria
AL485_RS05710	COG4566	intracellular signal transduction
AL485_RS05715	COG4191	Histidine kinase
AL485_RS05730	COG1686	Belongs to the peptidase S11 family
AL485_RS05735	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL485_RS05740	COG4977	sequence-specific DNA binding
AL485_RS05750	COG0586	Pfam SNARE associated Golgi protein
AL485_RS05755	COG1280	lysine exporter protein (LysE YggA)
AL485_RS05760	COG0583	DNA-binding transcription factor activity
AL485_RS05780	COG0583	DNA-binding transcription factor activity
AL485_RS05795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL485_RS05820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL485_RS05825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL485_RS05850	COG0513	Belongs to the DEAD box helicase family
AL485_RS05855	COG1309	transcriptional regulator
AL485_RS05860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS05865	COG1131	(ABC) transporter
AL485_RS05870	COG0842	Transport permease protein
AL485_RS05875	COG0842	Transport permease protein
AL485_RS05880	COG0670	Belongs to the BI1 family
AL485_RS05885	COG0314	molybdopterin synthase activity
AL485_RS05890	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL485_RS05895	COG0315	cyclic pyranopterin monophosphate synthase activity
AL485_RS05900	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL485_RS05905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL485_RS05910	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL485_RS05915	COG4628	conserved protein (DUF2132)
AL485_RS05920	COG0556	nucleotide-excision repair
AL485_RS05940	COG0156	8-amino-7-oxononanoate synthase activity
AL485_RS05945	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL485_RS05960	COG1881	PFAM PEBP family protein
AL485_RS05965	COG2706	6-phosphogluconolactonase activity
AL485_RS05970	COG0561	phosphatase activity
AL485_RS05980	COG4149	molybdate abc transporter
AL485_RS05985	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL485_RS05995	COG1120	ATPase activity
AL485_RS06000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL485_RS06005	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AL485_RS06015	COG4774	siderophore transport
AL485_RS06020	COG3585	molybdate ion transport
AL485_RS06020	COG2005	Transcriptional regulator
AL485_RS06025	COG1119	ATPase activity
AL485_RS06040	COG1085	galactose-1-phosphate uridylyltransferase
AL485_RS06045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AL485_RS06050	COG2017	converts alpha-aldose to the beta-anomer
AL485_RS06065	COG0588	phosphoglycerate mutase activity
AL485_RS06075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL485_RS06080	COG2197	response regulator
AL485_RS06085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL485_RS06085	COG2205	protein histidine kinase activity
AL485_RS06090	COG1230	cation diffusion facilitator family transporter
AL485_RS06100	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL485_RS06135	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL485_RS06140	COG2885	chlorophyll binding
AL485_RS06145	COG0823	Involved in the tonB-independent uptake of proteins
AL485_RS06150	COG3064	Membrane
AL485_RS06155	COG0848	biopolymer transport protein
AL485_RS06160	COG0811	peptide transport
AL485_RS06165	COG0824	Thioesterase
AL485_RS06170	COG3790	cyd operon protein YbgE
AL485_RS06175	COG4890	Cyd operon protein YbgT
AL485_RS06180	COG1294	oxidase, subunit
AL485_RS06185	COG1271	oxidase subunit
AL485_RS06190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL485_RS06195	COG0045	succinate-CoA ligase (ADP-forming) activity
AL485_RS06205	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL485_RS06210	COG0567	Dehydrogenase, E1 component
AL485_RS06215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL485_RS06225	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL485_RS06260	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL485_RS06265	COG1984	allophanate hydrolase subunit 2
AL485_RS06270	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL485_RS06275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL485_RS06280	COG5212	phosphodiesterase
AL485_RS06290	COG3272	Protein of unknown function (DUF1722)
AL485_RS06305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AL485_RS06310	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL485_RS06315	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL485_RS06320	COG2205	protein histidine kinase activity
AL485_RS06325	COG0745	RESPONSE REGULATOR receiver
AL485_RS06335	COG1695	Transcriptional regulator
AL485_RS06340	COG0033	Phosphoglucomutase
AL485_RS06345	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AL485_RS06350	COG0596	Alpha beta hydrolase
AL485_RS06365	COG0735	belongs to the Fur family
AL485_RS06385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL485_RS06395	COG0363	glucosamine-6-phosphate deaminase activity
AL485_RS06400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL485_RS06405	COG1846	Transcriptional regulator
AL485_RS06405	COG1940	carbohydrate kinase activity
AL485_RS06410	COG0647	UMP catabolic process
AL485_RS06415	COG3469	chitinase activity
AL485_RS06420	COG0367	asparagine synthase
AL485_RS06455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL485_RS06460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL485_RS06465	COG2824	Alkylphosphonate utilization operon protein PhnA
AL485_RS06470	COG1702	phosphate starvation-inducible protein PhoH
AL485_RS06475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL485_RS06480	COG4535	Mg2 and Co2 transporter CorC
AL485_RS06485	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL485_RS06495	COG0765	amino acid transport
AL485_RS06500	COG0765	amino acid transport
AL485_RS06505	COG1126	abc transporter atp-binding protein
AL485_RS06510	COG1957	nucleoside hydrolase
AL485_RS06520	COG2888	peptidyl-tyrosine sulfation
AL485_RS06525	COG0495	leucyl-tRNA aminoacylation
AL485_RS06530	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AL485_RS06535	COG1466	dna polymerase III delta subunit
AL485_RS06540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL485_RS06545	COG0799	negative regulation of ribosome biogenesis
AL485_RS06550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL485_RS06555	COG0768	penicillin binding
AL485_RS06560	COG0772	Belongs to the SEDS family
AL485_RS06565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL485_RS06570	COG1686	Belongs to the peptidase S11 family
AL485_RS06575	COG2921	Belongs to the UPF0250 family
AL485_RS06580	COG0321	lipoyl(octanoyl) transferase activity
AL485_RS06585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL485_RS06595	COG3706	GGDEF domain
AL485_RS06600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL485_RS06610	COG2814	Major facilitator Superfamily
AL485_RS06620	COG1473	amidohydrolase
AL485_RS06625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL485_RS06630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL485_RS06640	COG0765	amino acid transport
AL485_RS06645	COG1126	abc transporter atp-binding protein
AL485_RS06655	COG1278	Cold shock
AL485_RS06660	COG2199	diguanylate cyclase activity
AL485_RS06670	COG0583	DNA-binding transcription factor activity
AL485_RS06675	COG0667	Aldo Keto reductase
AL485_RS06680	COG2814	Major facilitator Superfamily
AL485_RS06690	COG0583	DNA-binding transcription factor activity
AL485_RS06700	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AL485_RS06705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL485_RS06720	COG1917	Cupin 2, conserved barrel domain protein
AL485_RS06740	COG0604	alcohol dehydrogenase
AL485_RS06745	COG0604	alcohol dehydrogenase
AL485_RS06755	COG2259	Doxx family
AL485_RS06795	COG2003	Belongs to the UPF0758 family
AL485_RS06820	COG3596	GTP binding
AL485_RS06835	COG4983	Phage plasmid primase, P4 family domain protein
AL485_RS06860	COG0737	Belongs to the 5'-nucleotidase family
AL485_RS06870	COG0737	Belongs to the 5'-nucleotidase family
AL485_RS06935	COG3539	Fimbrial protein
AL485_RS06945	COG3121	Chaperone
AL485_RS06950	COG3188	usher protein
AL485_RS06985	COG0582	viral genome integration into host DNA
AL485_RS07005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL485_RS07010	COG2501	S4 domain
AL485_RS07015	COG0215	cysteine-tRNA ligase activity
AL485_RS07020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL485_RS07025	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL485_RS07030	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL485_RS07035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL485_RS07045	COG2814	Major facilitator Superfamily
AL485_RS07050	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL485_RS07055	COG4181	ATPase activity
AL485_RS07060	COG2755	lipolytic protein G-D-S-L family
AL485_RS07065	COG0300	oxidoreductase activity
AL485_RS07070	COG3118	belongs to the thioredoxin family
AL485_RS07075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL485_RS07080	COG0330	HflC and HflK could
AL485_RS07085	COG1585	Membrane protein implicated in regulation of membrane protease activity
AL485_RS07090	COG0789	Transcriptional regulator
AL485_RS07095	COG2217	Heavy metal translocating P-type atpase
AL485_RS07100	COG3735	TraB family
AL485_RS07105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL485_RS07110	COG2020	methyltransferase activity
AL485_RS07115	COG0737	Belongs to the 5'-nucleotidase family
AL485_RS07120	COG2223	nitrite transmembrane transporter activity
AL485_RS07125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL485_RS07125	COG4651	solute:proton antiporter activity
AL485_RS07130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL485_RS07135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL485_RS07140	COG1929	Belongs to the glycerate kinase type-1 family
AL485_RS07145	COG2610	gluconate transmembrane transporter activity
AL485_RS07150	COG3835	regulator
AL485_RS07155	COG0563	adenylate kinase activity
AL485_RS07160	COG0326	Molecular chaperone. Has ATPase activity
AL485_RS07165	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL485_RS07170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL485_RS07175	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL485_RS07180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL485_RS07185	COG2832	Protein of unknown function (DUF454)
AL485_RS07200	COG1196	nuclear chromosome segregation
AL485_RS07200	COG3264	Mechanosensitive ion channel
AL485_RS07205	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL485_RS07210	COG1309	transcriptional regulator
AL485_RS07215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS07220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL485_RS07225	COG0254	rRNA binding
AL485_RS07230	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL485_RS07235	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL485_RS07240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL485_RS07245	COG1121	(ABC) transporter
AL485_RS07270	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AL485_RS07275	COG2252	PERMEase
AL485_RS07285	COG3695	enzyme binding
AL485_RS07290	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL485_RS07295	COG1946	Acyl-CoA thioesterase
AL485_RS07305	COG0688	phosphatidylethanolamine metabolic process
AL485_RS07310	COG2258	MOSC domain
AL485_RS07315	COG0004	ammonium transporteR
AL485_RS07320	COG0347	Belongs to the P(II) protein family
AL485_RS07325	COG1132	(ABC) transporter
AL485_RS07330	COG1132	(ABC) transporter
AL485_RS07335	COG1522	sequence-specific DNA binding
AL485_RS07340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL485_RS07345	COG0561	phosphatase activity
AL485_RS07350	COG4533	DNA binding
AL485_RS07355	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL485_RS07360	COG0824	Thioesterase
AL485_RS07365	COG1555	photosystem II stabilization
AL485_RS07370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL485_RS07380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL485_RS07385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL485_RS07395	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL485_RS07405	COG0271	Belongs to the BolA IbaG family
AL485_RS07410	COG3056	Lipoprotein
AL485_RS07415	COG2223	nitrite transmembrane transporter activity
AL485_RS07420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL485_RS07425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL485_RS07430	COG1845	cytochrome c oxidase, subunit III
AL485_RS07435	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL485_RS07440	COG0109	protoheme IX farnesyltransferase activity
AL485_RS07445	COG2814	Major facilitator Superfamily
AL485_RS07450	COG1666	GTP binding
AL485_RS07455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL485_RS07460	COG0693	protein deglycase activity
AL485_RS07465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL485_RS07465	COG0301	tRNA thio-modification
AL485_RS07470	COG1722	exodeoxyribonuclease VII activity
AL485_RS07475	COG0142	geranyltranstransferase activity
AL485_RS07480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL485_RS07485	COG0667	Aldo Keto reductase
AL485_RS07490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL485_RS07495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL485_RS07500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL485_RS07505	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL485_RS07510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL485_RS07510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL485_RS07515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL485_RS07520	COG4238	major outer membrane lipoprotein
AL485_RS07550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL485_RS07555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL485_RS07560	COG1862	Preprotein translocase
AL485_RS07565	COG0343	queuine tRNA-ribosyltransferase activity
AL485_RS07570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL485_RS07575	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AL485_RS07580	COG0450	alkyl hydroperoxide reductase
AL485_RS07590	COG0366	Alpha amylase catalytic
AL485_RS07595	COG0668	transmembrane transport
AL485_RS07615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL485_RS07625	COG5002	protein histidine kinase activity
AL485_RS07630	COG0745	RESPONSE REGULATOR receiver
AL485_RS07635	COG0420	3'-5' exonuclease activity
AL485_RS07640	COG0419	ATPase involved in DNA repair
AL485_RS07655	COG1940	carbohydrate kinase activity
AL485_RS07670	COG0191	fructose-bisphosphate aldolase activity
AL485_RS07685	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS07690	COG1129	ABC transporter
AL485_RS07700	COG2974	May be involved in recombination
AL485_RS07705	COG3123	guanosine phosphorylase activity
AL485_RS07710	COG4126	flavin adenine dinucleotide binding
AL485_RS07725	COG1414	Transcriptional regulator
AL485_RS07750	COG0667	Aldo Keto reductase
AL485_RS07755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL485_RS07805	COG2226	methyltransferase
AL485_RS07815	COG3416	Protein conserved in bacteria
AL485_RS07830	COG3011	Protein conserved in bacteria
AL485_RS07840	COG1335	isochorismatase
AL485_RS07855	COG0346	lactoylglutathione lyase activity
AL485_RS07860	COG1349	DNA-binding transcription factor activity
AL485_RS07890	COG3961	Belongs to the TPP enzyme family
AL485_RS07930	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS07935	COG2207	Transcriptional regulator
AL485_RS07945	COG3391	amine dehydrogenase activity
AL485_RS07950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL485_RS07955	COG4774	siderophore transport
AL485_RS07955	COG1629	transport
AL485_RS07960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL485_RS07965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL485_RS07965	COG2226	methyltransferase
AL485_RS07965	COG3433	isochorismatase activity
AL485_RS07980	COG0747	negative chemotaxis
AL485_RS07985	COG3038	cytochrome b561
AL485_RS08005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL485_RS08010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL485_RS08020	COG1073	alpha beta
AL485_RS08025	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL485_RS08030	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL485_RS08035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL485_RS08040	COG0584	glycerophosphoryl diester phosphodiesterase
AL485_RS08045	COG2991	Protein conserved in bacteria
AL485_RS08050	COG1477	protein flavinylation
AL485_RS08055	COG2871	sodium ion transport
AL485_RS08060	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL485_RS08065	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL485_RS08070	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL485_RS08075	COG1805	sodium ion transport
AL485_RS08080	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL485_RS08085	COG3034	peptidoglycan biosynthetic process
AL485_RS08090	COG0121	glutamine amidotransferase
AL485_RS08095	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL485_RS08100	COG1960	acyl-CoA dehydrogenase activity
AL485_RS08110	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AL485_RS08115	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AL485_RS08120	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AL485_RS08125	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AL485_RS08130	COG0235	Class ii aldolase
AL485_RS08135	COG0436	Aminotransferase
AL485_RS08150	COG2351	hydroxyisourate hydrolase activity
AL485_RS08165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL485_RS08170	COG1126	abc transporter atp-binding protein
AL485_RS08175	COG0765	amino acid transport
AL485_RS08225	COG2375	cellular response to nickel ion
AL485_RS08275	COG1953	Uracil, thiamine, allantoin
AL485_RS08285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL485_RS08290	COG0328	RNA-DNA hybrid ribonuclease activity
AL485_RS08295	COG2226	methyltransferase
AL485_RS08300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL485_RS08305	COG1388	LysM domain
AL485_RS08305	COG0741	lytic transglycosylase activity
AL485_RS08315	COG2814	Major facilitator Superfamily
AL485_RS08320	COG0583	DNA-binding transcription factor activity
AL485_RS08325	COG0656	L-ascorbic acid biosynthetic process
AL485_RS08335	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS08340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL485_RS08345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL485_RS08375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL485_RS08380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL485_RS08390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL485_RS08440	COG0542	response to heat
AL485_RS08450	COG0564	pseudouridine synthase activity
AL485_RS08460	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL485_RS08465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL485_RS08475	COG0077	Prephenate dehydratase
AL485_RS08475	COG1605	Chorismate mutase
AL485_RS08480	COG0287	Prephenate dehydrogenase
AL485_RS08480	COG1605	Chorismate mutase
AL485_RS08485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL485_RS08490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL485_RS08495	COG3137	Salt-induced outer membrane protein
AL485_RS08505	COG0335	large ribosomal subunit rRNA binding
AL485_RS08515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL485_RS08520	COG0228	four-way junction DNA binding
AL485_RS08525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL485_RS08530	COG4137	Cytochrome C assembly protein
AL485_RS08535	COG4536	flavin adenine dinucleotide binding
AL485_RS08540	COG1854	S-ribosylhomocysteine lyase activity
AL485_RS08545	COG2918	glutathione biosynthetic process
AL485_RS08550	COG1238	metal cluster binding
AL485_RS08555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL485_RS08595	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AL485_RS08600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL485_RS08605	COG2137	regulation of response to DNA damage stimulus
AL485_RS08610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL485_RS08630	COG2169	Transcriptional regulator
AL485_RS08630	COG1917	Cupin 2, conserved barrel domain protein
AL485_RS08635	COG2723	6-phospho-beta-galactosidase activity
AL485_RS08640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL485_RS08645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL485_RS08650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL485_RS08655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL485_RS08660	COG1388	LysM domain
AL485_RS08660	COG4942	peptidase
AL485_RS08670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL485_RS08675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL485_RS08680	COG0585	pseudouridine synthase activity
AL485_RS08685	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL485_RS08690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL485_RS08695	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL485_RS08705	COG0765	amino acid transport
AL485_RS08720	COG0529	Catalyzes the synthesis of activated sulfate
AL485_RS08725	COG2895	sulfate adenylyltransferase (ATP) activity
AL485_RS08730	COG0175	sulfate reduction
AL485_RS08735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL485_RS08735	COG1648	precorrin-2 dehydrogenase activity
AL485_RS08740	COG2234	aminopeptidase activity
AL485_RS08745	COG0175	sulfate reduction
AL485_RS08750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL485_RS08755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL485_RS08760	COG0720	synthase
AL485_RS08765	COG0602	queuosine metabolic process
AL485_RS08770	COG2271	Major facilitator Superfamily
AL485_RS08775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL485_RS08780	COG2986	histidine ammonia-lyase
AL485_RS08795	COG4176	ABC-type proline glycine betaine transport system permease component
AL485_RS08800	COG4175	Glycine betaine
AL485_RS08805	COG2986	histidine ammonia-lyase
AL485_RS08825	COG0148	phosphopyruvate hydratase activity
AL485_RS08830	COG0504	CTP synthase activity
AL485_RS08835	COG3956	TIGRFAM MazG family protein
AL485_RS08840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL485_RS08845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL485_RS08855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL485_RS08860	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL485_RS08865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL485_RS08875	COG2860	membrane
AL485_RS08885	COG0316	Belongs to the HesB IscA family
AL485_RS08895	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL485_RS08900	COG3725	Membrane protein required for beta-lactamase induction
AL485_RS08905	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL485_RS08930	COG3423	Transcriptional regulator
AL485_RS08985	COG4969	Belongs to the N-Me-Phe pilin family
AL485_RS08990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL485_RS08995	COG1459	type II secretion system
AL485_RS09000	COG0516	GMP reductase activity
AL485_RS09015	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL485_RS09020	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL485_RS09025	COG0494	nUDIX hydrolase
AL485_RS09030	COG0653	protein targeting
AL485_RS09050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL485_RS09055	COG0849	cell division
AL485_RS09060	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL485_RS09070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL485_RS09075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL485_RS09080	COG0772	Belongs to the SEDS family
AL485_RS09090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL485_RS09095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL485_RS09100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL485_RS09105	COG0768	penicillin binding
AL485_RS09110	COG3116	cell division
AL485_RS09115	COG0275	rRNA processing
AL485_RS09120	COG2001	Belongs to the MraZ family
AL485_RS09140	COG0028	Belongs to the TPP enzyme family
AL485_RS09145	COG1022	Amp-dependent synthetase and ligase
AL485_RS09160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL485_RS09165	COG0473	3-isopropylmalate dehydrogenase activity
AL485_RS09170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL485_RS09175	COG0066	3-isopropylmalate dehydratase activity
AL485_RS09180	COG0471	metal ion transport
AL485_RS09185	COG2814	Major facilitator Superfamily
AL485_RS09200	COG4143	(ABC) transporter
AL485_RS09205	COG1178	ABC-type Fe3 transport system permease component
AL485_RS09220	COG0028	Belongs to the TPP enzyme family
AL485_RS09225	COG0440	acetolactate synthase activity
AL485_RS09230	COG0586	Pfam SNARE associated Golgi protein
AL485_RS09235	COG0417	DNA replication proofreading
AL485_RS09240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL485_RS09245	COG0564	pseudouridine synthase activity
AL485_RS09255	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL485_RS09265	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL485_RS09270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL485_RS09275	COG2967	ApaG domain
AL485_RS09280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL485_RS09290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL485_RS09300	COG2966	Psort location CytoplasmicMembrane, score
AL485_RS09315	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL485_RS09320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL485_RS09330	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL485_RS09335	COG2186	Transcriptional regulator
AL485_RS09340	COG3734	2-keto-3-deoxy-galactonokinase
AL485_RS09345	COG0800	Aldolase
AL485_RS09350	COG2814	Major facilitator Superfamily
AL485_RS09355	COG2271	Major facilitator Superfamily
AL485_RS09360	COG0129	dihydroxy-acid dehydratase activity
AL485_RS09365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL485_RS09370	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS09395	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL485_RS09400	COG1047	Peptidyl-prolyl cis-trans
AL485_RS09405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL485_RS09410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL485_RS09415	COG0196	riboflavin kinase activity
AL485_RS09420	COG0268	Binds directly to 16S ribosomal RNA
AL485_RS09425	COG0583	DNA-binding transcription factor activity
AL485_RS09430	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL485_RS09435	COG0484	heat shock protein binding
AL485_RS09440	COG0443	Heat shock 70 kDa protein
AL485_RS09445	COG1584	GPR1 FUN34 yaaH family protein
AL485_RS09455	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL485_RS09460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL485_RS09465	COG1115	amino acid carrier protein
AL485_RS09470	COG3022	response to hydroperoxide
AL485_RS09480	COG0083	homoserine kinase activity
AL485_RS09500	COG0745	RESPONSE REGULATOR receiver
AL485_RS09505	COG3045	CreA protein
AL485_RS09510	COG2207	Transcriptional regulator
AL485_RS09510	COG3708	Transcriptional regulator
AL485_RS09515	COG0406	alpha-ribazole phosphatase activity
AL485_RS09520	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AL485_RS09525	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AL485_RS09530	COG0741	lytic transglycosylase activity
AL485_RS09540	COG2199	diguanylate cyclase activity
AL485_RS09545	COG2885	chlorophyll binding
AL485_RS09550	COG0488	(ABC) transporter
AL485_RS09560	COG0604	alcohol dehydrogenase
AL485_RS09575	COG0560	Phosphoserine phosphatase
AL485_RS09580	COG3726	membrane protein affecting hemolysin expression
AL485_RS09590	COG0813	purine-nucleoside phosphorylase activity
AL485_RS09595	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AL485_RS09600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AL485_RS09605	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AL485_RS09610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL485_RS09615	COG0084	hydrolase, TatD family'
AL485_RS09620	COG4667	esterase of the alpha-beta hydrolase superfamily
AL485_RS09625	COG3237	CsbD-like
AL485_RS09630	COG5487	UPF0391 membrane protein
AL485_RS09635	COG2823	Periplasmic or secreted lipoprotein
AL485_RS09640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL485_RS09650	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AL485_RS09660	COG2813	Specifically methylates the guanine in position
AL485_RS09665	COG0667	Aldo Keto reductase
AL485_RS09700	COG0738	Major facilitator superfamily
AL485_RS09705	COG3254	rhamnose metabolic process
AL485_RS09710	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS09715	COG3618	amidohydrolase
AL485_RS09720	COG4948	Mandelate Racemase Muconate Lactonizing
AL485_RS09725	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL485_RS09730	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS09740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL485_RS09745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL485_RS09750	COG2368	4-hydroxyphenylacetate
AL485_RS09775	COG3971	2-oxopent-4-enoate hydratase activity
AL485_RS09790	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS09805	COG1846	Transcriptional regulator
AL485_RS09810	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS09830	COG1113	amino acid transport
AL485_RS09850	COG2267	carboxylic ester hydrolase activity
AL485_RS09860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL485_RS09870	COG1454	alcohol dehydrogenase
AL485_RS09910	COG0811	peptide transport
AL485_RS09935	COG1376	ErfK ybiS ycfS ynhG family protein
AL485_RS09940	COG2207	Transcriptional regulator
AL485_RS09940	COG3708	Transcriptional regulator
AL485_RS09950	COG2207	Transcriptional regulator
AL485_RS09960	COG3391	amine dehydrogenase activity
AL485_RS09970	COG0174	glutamine synthetase
AL485_RS09990	COG1966	Carbon starvation protein
AL485_RS09995	COG2879	small protein
AL485_RS10000	COG0523	cobalamin synthesis protein
AL485_RS10015	COG1609	Transcriptional regulator
AL485_RS10020	COG1263	PTS System
AL485_RS10020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS10030	COG2723	6-phospho-beta-galactosidase activity
AL485_RS10050	COG1401	restriction endodeoxyribonuclease activity
AL485_RS10065	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL485_RS10075	COG1396	sequence-specific DNA binding
AL485_RS10090	COG1280	lysine exporter protein (LysE YggA)
AL485_RS10110	COG0795	lipopolysaccharide-transporting ATPase activity
AL485_RS10115	COG0795	lipopolysaccharide-transporting ATPase activity
AL485_RS10120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL485_RS10125	COG2927	DNA polymerase III (CHI subunit)
AL485_RS10135	COG0456	acetyltransferase
AL485_RS10145	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AL485_RS10155	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AL485_RS10160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL485_RS10175	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL485_RS10190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL485_RS10200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL485_RS10205	COG0540	Belongs to the ATCase OTCase family
AL485_RS10210	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AL485_RS10225	COG2308	Evidence 4 Homologs of previously reported genes of
AL485_RS10265	COG1263	PTS System
AL485_RS10265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS10270	COG0366	Alpha amylase catalytic
AL485_RS10275	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL485_RS10280	COG0583	DNA-binding transcription factor activity
AL485_RS10310	COG0701	Predicted permease
AL485_RS10315	COG2188	Transcriptional regulator
AL485_RS10320	COG3624	Phosphonate C-P lyase system protein PhnG
AL485_RS10325	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL485_RS10330	COG3626	phosphonate metabolism
AL485_RS10335	COG3627	carbon phosphorus lyase activity
AL485_RS10340	COG4107	phosphonate C-P lyase system protein PhnK
AL485_RS10345	COG4778	phosphonate C-P lyase system protein PhnL
AL485_RS10350	COG3454	Phosphonate metabolism
AL485_RS10355	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL485_RS10365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AL485_RS10370	COG0702	epimerase
AL485_RS10375	COG3787	Belongs to the UPF0306 family
AL485_RS10380	COG1982	Orn Lys Arg decarboxylase major
AL485_RS10385	COG0531	amino acid
AL485_RS10395	COG3153	acetyltransferase
AL485_RS10400	COG3154	lipid carrier protein
AL485_RS10405	COG0826	peptidase U32
AL485_RS10410	COG0826	peptidase U32
AL485_RS10415	COG2850	peptidyl-arginine hydroxylation
AL485_RS10435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL485_RS10440	COG0425	Belongs to the sulfur carrier protein TusA family
AL485_RS10445	COG2391	methyltransferase activity
AL485_RS10450	COG0513	Belongs to the DEAD box helicase family
AL485_RS10465	COG1185	polyribonucleotide nucleotidyltransferase activity
AL485_RS10475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL485_RS10480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL485_RS10485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL485_RS10490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL485_RS10495	COG0195	Participates in both transcription termination and antitermination
AL485_RS10500	COG0779	Required for maturation of 30S ribosomal subunits
AL485_RS10515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL485_RS10520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL485_RS10525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL485_RS10530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL485_RS10535	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL485_RS10540	COG1534	Rna-binding protein
AL485_RS10550	COG2027	D-alanyl-D-alanine carboxypeptidase
AL485_RS10555	COG0745	RESPONSE REGULATOR receiver
AL485_RS10560	COG0642	Histidine kinase
AL485_RS10565	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL485_RS10570	COG0697	spore germination
AL485_RS10575	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL485_RS10580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL485_RS10585	COG0142	geranyltranstransferase activity
AL485_RS10595	COG3423	Transcriptional regulator
AL485_RS10600	COG0039	L-malate dehydrogenase activity
AL485_RS10605	COG1438	arginine binding
AL485_RS10620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL485_RS10625	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL485_RS10630	COG0840	transmembrane signaling receptor activity
AL485_RS10635	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL485_RS10640	COG2105	PFAM AIG2 family protein
AL485_RS10645	COG2911	Protein conserved in bacteria
AL485_RS10650	COG0729	surface antigen
AL485_RS10655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL485_RS10660	COG1253	flavin adenine dinucleotide binding
AL485_RS10670	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL485_RS10675	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL485_RS10680	COG0737	Belongs to the 5'-nucleotidase family
AL485_RS10685	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AL485_RS10690	COG0545	Peptidyl-prolyl cis-trans isomerase
AL485_RS10695	COG3061	Opacity-associated protein A
AL485_RS10705	COG0359	binds to the 23S rRNA
AL485_RS10710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL485_RS10720	COG0360	Binds together with S18 to 16S ribosomal RNA
AL485_RS10730	COG1073	alpha beta
AL485_RS10735	COG3650	response to hydrogen peroxide
AL485_RS10745	COG3766	membrane
AL485_RS10750	COG1960	acyl-CoA dehydrogenase activity
AL485_RS10755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL485_RS10760	COG0557	exoribonuclease II activity
AL485_RS10765	COG1959	2 iron, 2 sulfur cluster binding
AL485_RS10770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL485_RS10775	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL485_RS10780	COG0330	HflC and HflK could
AL485_RS10785	COG0330	HflC and HflK could
AL485_RS10790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL485_RS10795	COG1923	regulation of RNA biosynthetic process
AL485_RS10800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL485_RS10805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL485_RS10810	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL485_RS10815	COG0802	atpase or kinase
AL485_RS10820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL485_RS10820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL485_RS10825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL485_RS10845	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL485_RS10850	COG1162	GTPase activity
AL485_RS10855	COG0688	phosphatidylethanolamine metabolic process
AL485_RS10860	COG3264	Mechanosensitive ion channel
AL485_RS10860	COG1511	domain protein
AL485_RS10865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AL485_RS10870	COG1053	succinate dehydrogenase
AL485_RS10875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL485_RS10880	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL485_RS10885	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL485_RS10900	COG5510	response to toxic substance
AL485_RS10910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL485_RS10930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL485_RS10950	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL485_RS10960	COG4232	protein-disulfide reductase activity
AL485_RS10965	COG1309	transcriptional regulator
AL485_RS10975	COG2198	Histidine kinase
AL485_RS10975	COG2205	protein histidine kinase activity
AL485_RS10975	COG0784	Response regulator, receiver
AL485_RS10980	COG1879	ABC-type sugar transport system periplasmic component
AL485_RS10985	COG0745	RESPONSE REGULATOR receiver
AL485_RS10990	COG3005	denitrification pathway
AL485_RS10995	COG0243	molybdopterin cofactor binding
AL485_RS11030	COG3647	Membrane
AL485_RS11035	COG4942	peptidase
AL485_RS11040	COG1301	dicarboxylic acid transport
AL485_RS11045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL485_RS11050	COG3162	membrane
AL485_RS11055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL485_RS11085	COG0138	bifunctional purine biosynthesis protein purh
AL485_RS11090	COG0151	Belongs to the GarS family
AL485_RS11110	COG1515	deoxyribonuclease V activity
AL485_RS11115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL485_RS11120	COG2816	NAD+ diphosphatase activity
AL485_RS11125	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL485_RS11135	COG0352	thiamine-phosphate diphosphorylase activity
AL485_RS11140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL485_RS11145	COG2104	thiamine diphosphate biosynthetic process
AL485_RS11150	COG2022	thiamine diphosphate biosynthetic process
AL485_RS11170	COG2205	protein histidine kinase activity
AL485_RS11185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL485_RS11190	COG0085	RNA polymerase activity
AL485_RS11195	COG0222	ribosome binding
AL485_RS11200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL485_RS11210	COG0081	regulation of translation
AL485_RS11220	COG0250	Participates in transcription elongation, termination and antitermination
AL485_RS11235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL485_RS11270	COG1072	(Pantothenic acid kinase))
AL485_RS11275	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AL485_RS11275	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AL485_RS11280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL485_RS11310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL485_RS11315	COG1739	Uncharacterized protein family UPF0029
AL485_RS11320	COG0006	proline dipeptidase activity
AL485_RS11325	COG2271	Major facilitator Superfamily
AL485_RS11330	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL485_RS11330	COG1024	Enoyl-CoA hydratase
AL485_RS11335	COG0183	Belongs to the thiolase family
AL485_RS11365	COG0084	hydrolase, TatD family'
AL485_RS11370	COG0805	protein transport
AL485_RS11380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL485_RS11385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL485_RS11390	COG3165	ubiquinone biosynthetic process from chorismate
AL485_RS11395	COG2226	methyltransferase
AL485_RS11400	COG1322	Protein conserved in bacteria
AL485_RS11405	COG0586	Pfam SNARE associated Golgi protein
AL485_RS11420	COG0412	Dienelactone hydrolase
AL485_RS11425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL485_RS11450	COG0584	glycerophosphoryl diester phosphodiesterase
AL485_RS11455	COG3842	ATPase activity
AL485_RS11465	COG1175	transmembrane transport
AL485_RS11470	COG1653	transport
AL485_RS11475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL485_RS11480	COG0410	ABC transporter
AL485_RS11495	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL485_RS11505	COG0456	acetyltransferase
AL485_RS11525	COG2177	Part of the ABC transporter FtsEX involved in
AL485_RS11530	COG2884	Cell division ATP-binding protein ftsE
AL485_RS11535	COG0552	protein localization to endoplasmic reticulum
AL485_RS11535	COG0552	protein localization to endoplasmic reticulum
AL485_RS11540	COG0742	ribosomal rna small subunit methyltransferase
AL485_RS11545	COG3776	membrane
AL485_RS11555	COG2197	response regulator
AL485_RS11575	COG0582	viral genome integration into host DNA
AL485_RS11590	COG0582	viral genome integration into host DNA
AL485_RS11595	COG3714	YhhN family
AL485_RS11630	COG0425	Belongs to the sulfur carrier protein TusA family
AL485_RS11635	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL485_RS11640	COG0456	acetyltransferase
AL485_RS11650	COG0247	lactate metabolic process
AL485_RS11660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL485_RS11670	COG2271	Major facilitator Superfamily
AL485_RS11675	COG0584	glycerophosphoryl diester phosphodiesterase
AL485_RS11680	COG0561	phosphatase activity
AL485_RS11685	COG2267	carboxylic ester hydrolase activity
AL485_RS11690	COG1280	lysine exporter protein (LysE YggA)
AL485_RS11695	COG1280	lysine exporter protein (LysE YggA)
AL485_RS11700	COG0514	ATP-dependent DNA helicase (RecQ)
AL485_RS11705	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AL485_RS11710	COG2050	protein possibly involved in aromatic compounds catabolism
AL485_RS11720	COG3180	Ammonia monooxygenase
AL485_RS11740	COG0210	DNA helicase
AL485_RS11745	COG1011	Hydrolase
AL485_RS11755	COG3159	Protein conserved in bacteria
AL485_RS11760	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL485_RS11770	COG1965	Belongs to the frataxin family
AL485_RS11775	COG3072	Adenylate cyclase
AL485_RS11780	COG0181	hydroxymethylbilane synthase activity
AL485_RS11790	COG2959	enzyme of heme biosynthesis
AL485_RS11795	COG3071	HemY protein
AL485_RS11830	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AL485_RS11840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL485_RS11845	COG2244	polysaccharide biosynthetic process
AL485_RS11850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL485_RS11855	COG0456	acetyltransferase
AL485_RS11860	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL485_RS11865	COG1088	dTDP-glucose 4,6-dehydratase activity
AL485_RS11870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL485_RS11875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL485_RS11885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL485_RS11890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL485_RS11895	COG3118	belongs to the thioredoxin family
AL485_RS11900	COG0513	Belongs to the DEAD box helicase family
AL485_RS11905	COG0248	Ppx GppA phosphatase
AL485_RS11915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL485_RS11920	COG0612	Peptidase, M16
AL485_RS11925	COG1301	dicarboxylic acid transport
AL485_RS11930	COG2200	EAL domain
AL485_RS11930	COG2199	diguanylate cyclase activity
AL485_RS11935	COG0457	Tetratricopeptide repeat
AL485_RS11935	COG3118	belongs to the thioredoxin family
AL485_RS11940	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AL485_RS11945	COG1215	transferase activity, transferring glycosyl groups
AL485_RS11950	COG1215	transferase activity, transferring glycosyl groups
AL485_RS11975	COG2194	sulfuric ester hydrolase activity
AL485_RS11980	COG4608	Belongs to the ABC transporter superfamily
AL485_RS11985	COG0444	Belongs to the ABC transporter superfamily
AL485_RS11990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL485_RS11995	COG0601	transmembrane transport
AL485_RS12000	COG0747	negative chemotaxis
AL485_RS12030	COG2271	Major facilitator Superfamily
AL485_RS12040	COG2197	response regulator
AL485_RS12045	COG2194	sulfuric ester hydrolase activity
AL485_RS12050	COG1764	response to oxidative stress
AL485_RS12055	COG1846	Transcriptional regulator
AL485_RS12105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL485_RS12110	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL485_RS12115	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS12120	COG1609	Transcriptional regulator
AL485_RS12160	COG2807	transmembrane transport
AL485_RS12165	COG0583	DNA-binding transcription factor activity
AL485_RS12180	COG1609	Transcriptional regulator
AL485_RS12180	COG2207	Transcriptional regulator
AL485_RS12185	COG4214	carbohydrate transport
AL485_RS12195	COG4213	ABC transporter substrate-binding protein
AL485_RS12200	COG2115	Belongs to the xylose isomerase family
AL485_RS12205	COG1070	Carbohydrate kinase
AL485_RS12210	COG0402	S-adenosylhomocysteine deaminase activity
AL485_RS12215	COG1335	isochorismatase
AL485_RS12225	COG3274	enterobacterial common antigen metabolic process
AL485_RS12240	COG3276	selenocysteine insertion sequence binding
AL485_RS12245	COG1921	L-seryl-tRNASec selenium transferase activity
AL485_RS12250	COG0625	glutathione transferase activity
AL485_RS12265	COG3058	Necessary for formate dehydrogenase activity
AL485_RS12270	COG2864	formate dehydrogenase
AL485_RS12275	COG0437	4 iron, 4 sulfur cluster binding
AL485_RS12290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL485_RS12300	COG2258	MOSC domain
AL485_RS12315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL485_RS12325	COG3722	fumarate hydratase activity
AL485_RS12330	COG0246	Mannitol dehydrogenase
AL485_RS12335	COG2213	PTS system mannitol-specific
AL485_RS12335	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL485_RS12350	COG0751	glycine-tRNA ligase activity
AL485_RS12355	COG0752	glycyl-tRNA synthetase alpha subunit
AL485_RS12360	COG2271	Major facilitator Superfamily
AL485_RS12370	COG2818	Glycosylase
AL485_RS12375	COG0456	acetyltransferase
AL485_RS12380	COG2885	chlorophyll binding
AL485_RS12385	COG1609	Transcriptional regulator
AL485_RS12395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL485_RS12400	COG2814	Major facilitator Superfamily
AL485_RS12405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL485_RS12410	COG0366	Alpha amylase catalytic
AL485_RS12415	COG3977	Valine--pyruvate aminotransferase
AL485_RS12420	COG2985	domain, Protein
AL485_RS12425	COG0071	Belongs to the small heat shock protein (HSP20) family
AL485_RS12430	COG0071	Belongs to the small heat shock protein (HSP20) family
AL485_RS12440	COG5645	(Lipo)protein
AL485_RS12445	COG0823	Involved in the tonB-independent uptake of proteins
AL485_RS12450	COG2271	Major facilitator Superfamily
AL485_RS12460	COG4948	Mandelate Racemase Muconate Lactonizing
AL485_RS12465	COG0800	Aldolase
AL485_RS12470	COG3734	2-keto-3-deoxy-galactonokinase
AL485_RS12475	COG2186	Transcriptional regulator
AL485_RS12480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL485_RS12485	COG2423	ornithine cyclodeaminase activity
AL485_RS12490	COG0561	phosphatase activity
AL485_RS12495	COG0187	DNA topoisomerase II activity
AL485_RS12500	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL485_RS12505	COG0592	DNA-directed DNA polymerase activity
AL485_RS12510	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL485_RS12520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL485_RS12525	COG0594	ribonuclease P activity
AL485_RS12530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL485_RS12535	COG0706	membrane insertase activity
AL485_RS12540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL485_RS12555	COG2091	lysine biosynthetic process via aminoadipic acid
AL485_RS12560	COG0431	NADPH-dependent FMN reductase
AL485_RS12570	COG2252	PERMEase
AL485_RS12575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL485_RS12580	COG0765	amino acid transport
AL485_RS12585	COG0765	amino acid transport
AL485_RS12590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL485_RS12595	COG0704	Plays a role in the regulation of phosphate uptake
AL485_RS12605	COG0581	inorganic phosphate transmembrane transporter activity
AL485_RS12610	COG0573	inorganic phosphate transmembrane transporter activity
AL485_RS12615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL485_RS12625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL485_RS12630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL485_RS12635	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL485_RS12640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL485_RS12645	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL485_RS12650	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL485_RS12655	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL485_RS12670	COG3312	ion transport
AL485_RS12675	COG0357	Ribosomal RNA small subunit methyltransferase G
AL485_RS12680	COG0445	tRNA wobble uridine modification
AL485_RS12685	COG0716	FMN binding
AL485_RS12690	COG1522	sequence-specific DNA binding
AL485_RS12695	COG2502	aspartate--ammonia ligase
AL485_RS12700	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL485_RS12705	COG0714	Associated with various cellular activities
AL485_RS12710	COG3158	transport of potassium into the cell
AL485_RS12715	COG1869	D-ribose catabolic process
AL485_RS12720	COG1129	ABC transporter
AL485_RS12725	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS12735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL485_RS12740	COG1609	Transcriptional regulator
AL485_RS12745	COG0477	Major facilitator Superfamily
AL485_RS12750	COG2186	Transcriptional regulator
AL485_RS12775	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL485_RS12780	COG0746	molybdenum cofactor guanylyltransferase activity
AL485_RS12785	COG3084	Protein conserved in bacteria
AL485_RS12790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL485_RS12795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL485_RS12800	COG0204	Acyl-transferase
AL485_RS12805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL485_RS12805	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL485_RS12810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL485_RS12820	COG3078	GTPase activator activity
AL485_RS12830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL485_RS12840	COG3852	Histidine kinase
AL485_RS12845	COG0174	glutamine synthetase
AL485_RS12850	COG1217	gtp-binding protein TYPA
AL485_RS12855	COG1011	Hydrolase
AL485_RS12860	COG1295	ribonuclease BN
AL485_RS12865	COG1490	D-aminoacyl-tRNA deacylase activity
AL485_RS12870	COG0456	acetyltransferase
AL485_RS12880	COG2982	Protein involved in outer membrane biogenesis
AL485_RS12885	COG2233	PERMEase
AL485_RS12890	COG0786	glutamate:sodium symporter activity
AL485_RS12895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL485_RS12900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL485_RS12905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL485_RS12910	COG1758	RNA polymerase activity
AL485_RS12915	COG0194	GDP metabolic process
AL485_RS12925	COG2860	membrane
AL485_RS12935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL485_RS12940	COG4221	oxidoreductase activity
AL485_RS12945	COG1561	YicC-like family, N-terminal region
AL485_RS12950	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL485_RS12955	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL485_RS12960	COG1309	transcriptional regulator
AL485_RS12965	COG0756	dUTP diphosphatase activity
AL485_RS12970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL485_RS12975	COG2003	Belongs to the UPF0758 family
AL485_RS12980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL485_RS12990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL485_RS12995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL485_RS13005	COG1519	Transferase
AL485_RS13015	COG0438	transferase activity, transferring glycosyl groups
AL485_RS13020	COG0438	transferase activity, transferring glycosyl groups
AL485_RS13025	COG0859	PFAM glycosyl transferase family 9
AL485_RS13035	COG0859	PFAM glycosyl transferase family 9
AL485_RS13050	COG0859	PFAM glycosyl transferase family 9
AL485_RS13055	COG0859	PFAM glycosyl transferase family 9
AL485_RS13060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL485_RS13065	COG0156	8-amino-7-oxononanoate synthase activity
AL485_RS13070	COG1063	alcohol dehydrogenase
AL485_RS13075	COG2861	carbohydrate metabolic process
AL485_RS13080	COG4942	peptidase
AL485_RS13085	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL485_RS13090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL485_RS13095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL485_RS13100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL485_RS13105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL485_RS13110	COG1045	serine acetyltransferase
AL485_RS13125	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL485_RS13130	COG2205	protein histidine kinase activity
AL485_RS13135	COG0745	RESPONSE REGULATOR receiver
AL485_RS13140	COG3678	ATP-independent chaperone mediated protein folding
AL485_RS13145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL485_RS13150	COG0205	6-phosphofructokinase activity
AL485_RS13155	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AL485_RS13160	COG0149	triose-phosphate isomerase activity
AL485_RS13170	COG3152	Membrane
AL485_RS13185	COG2814	Major facilitator Superfamily
AL485_RS13195	COG1494	fructose-1,6-bisphosphatase
AL485_RS13205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL485_RS13215	COG3074	FtsZ-dependent cytokinesis
AL485_RS13220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL485_RS13225	COG1575	Belongs to the MenA family. Type 1 subfamily
AL485_RS13230	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL485_RS13235	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL485_RS13240	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL485_RS13245	COG1609	Transcriptional regulator
AL485_RS13250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL485_RS13255	COG0254	rRNA binding
AL485_RS13260	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AL485_RS13265	COG0626	cystathionine gamma-synthase activity
AL485_RS13270	COG0460	homoserine dehydrogenase
AL485_RS13270	COG0527	aspartate kinase activity
AL485_RS13275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL485_RS13280	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL485_RS13295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL485_RS13300	COG0137	argininosuccinate synthase activity
AL485_RS13305	COG0165	Argininosuccinate lyase
AL485_RS13315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL485_RS13320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL485_RS13320	COG0678	peroxiredoxin activity
AL485_RS13330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL485_RS13345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL485_RS13350	COG4206	TonB-dependent receptor
AL485_RS13355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL485_RS13395	COG1879	ABC-type sugar transport system periplasmic component
AL485_RS13400	COG1129	ABC transporter
AL485_RS13405	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS13410	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS13415	COG0583	DNA-binding transcription factor activity
AL485_RS13420	COG3085	chromosome segregation
AL485_RS13425	COG0606	chelatase, subunit chli
AL485_RS13430	COG2814	Major facilitator Superfamily
AL485_RS13445	COG3978	acetolactate synthase activity
AL485_RS13450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL485_RS13455	COG0129	dihydroxy-acid dehydratase activity
AL485_RS13460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL485_RS13470	COG0583	DNA-binding transcription factor activity
AL485_RS13475	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL485_RS13480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL485_RS13485	COG1942	4-Oxalocrotonate Tautomerase
AL485_RS13490	COG2200	EAL domain
AL485_RS13495	COG2982	Protein involved in outer membrane biogenesis
AL485_RS13500	COG2134	cdp-diacylglycerol pyrophosphatase
AL485_RS13505	COG0477	Major facilitator Superfamily
AL485_RS13510	COG1295	ribonuclease BN
AL485_RS13515	COG1024	Enoyl-CoA hydratase
AL485_RS13520	COG5001	Diguanylate cyclase
AL485_RS13525	COG3678	ATP-independent chaperone mediated protein folding
AL485_RS13545	COG0784	Response regulator, receiver
AL485_RS13545	COG2205	protein histidine kinase activity
AL485_RS13555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL485_RS13560	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL485_RS13575	COG0154	amidase activity
AL485_RS13585	COG0339	signal peptide processing
AL485_RS13590	COG0742	ribosomal rna small subunit methyltransferase
AL485_RS13595	COG0737	Belongs to the 5'-nucleotidase family
AL485_RS13600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL485_RS13600	COG0517	IMP dehydrogenase activity
AL485_RS13610	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS13615	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS13620	COG1129	ABC transporter
AL485_RS13635	COG0589	response to stress
AL485_RS13645	COG0306	phosphate transporter
AL485_RS13650	COG2081	HI0933 family
AL485_RS13695	COG2197	response regulator
AL485_RS13725	COG3188	usher protein
AL485_RS13755	COG4619	ABC transporter
AL485_RS13760	COG0390	transport system, permease component
AL485_RS13770	COG0477	Major facilitator Superfamily
AL485_RS13770	COG2814	Major facilitator Superfamily
AL485_RS13785	COG3718	enzyme involved in inositol metabolism
AL485_RS13795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL485_RS13800	COG3962	Belongs to the TPP enzyme family
AL485_RS13805	COG0673	inositol 2-dehydrogenase activity
AL485_RS13810	COG1082	Xylose isomerase domain protein TIM barrel
AL485_RS13815	COG1082	Xylose isomerase domain protein TIM barrel
AL485_RS13820	COG3191	aminopeptidase activity
AL485_RS13825	COG1247	-acetyltransferase
AL485_RS13835	COG1741	Belongs to the pirin family
AL485_RS13840	COG1609	Transcriptional regulator
AL485_RS13845	COG2610	gluconate transmembrane transporter activity
AL485_RS13850	COG3265	gluconokinase activity
AL485_RS13855	COG2095	MarC family integral membrane protein
AL485_RS13860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL485_RS13865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL485_RS13870	COG1523	belongs to the glycosyl hydrolase 13 family
AL485_RS13875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL485_RS13880	COG0297	glycogen (starch) synthase activity
AL485_RS13885	COG0058	SHG alpha-glucan phosphorylase activity
AL485_RS13890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL485_RS13895	COG1349	DNA-binding transcription factor activity
AL485_RS13900	COG0705	Rhomboid family
AL485_RS13905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL485_RS13955	COG2909	trisaccharide binding
AL485_RS13965	COG0058	SHG alpha-glucan phosphorylase activity
AL485_RS13970	COG1640	4-alpha-glucanotransferase
AL485_RS13975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AL485_RS13975	COG0316	Belongs to the HesB IscA family
AL485_RS13980	COG1040	competence protein
AL485_RS13985	COG2267	carboxylic ester hydrolase activity
AL485_RS14005	COG1918	ferrous iron import across plasma membrane
AL485_RS14010	COG2183	response to ionizing radiation
AL485_RS14015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL485_RS14045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL485_RS14050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL485_RS14055	COG1011	Hydrolase
AL485_RS14065	COG0494	nUDIX hydrolase
AL485_RS14070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL485_RS14095	COG4796	Type ii and iii secretion system protein
AL485_RS14105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL485_RS14110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL485_RS14130	COG0546	phosphoglycolate phosphatase activity
AL485_RS14135	COG0180	Tryptophanyl-tRNA synthetase
AL485_RS14140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL485_RS14140	COG1648	precorrin-2 dehydrogenase activity
AL485_RS14155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL485_RS14165	COG0402	S-adenosylhomocysteine deaminase activity
AL485_RS14170	COG0738	Major facilitator superfamily
AL485_RS14175	COG1609	Transcriptional regulator
AL485_RS14180	COG1486	melibiose metabolic process
AL485_RS14185	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL485_RS14190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL485_RS14195	COG3275	phosphorelay sensor kinase activity
AL485_RS14215	COG0433	COG0433 Predicted ATPase
AL485_RS14230	COG1289	transmembrane transporter activity
AL485_RS14235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL485_RS14240	COG1765	OsmC-like protein
AL485_RS14245	COG3954	Phosphoribulokinase
AL485_RS14250	COG3089	Belongs to the UPF0270 family
AL485_RS14255	COG0429	hydrolase of the alpha beta-hydrolase fold
AL485_RS14270	COG4521	taurine ABC transporter
AL485_RS14280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL485_RS14285	COG2175	clavaminate synthase activity
AL485_RS14290	COG0488	(ABC) transporter
AL485_RS14295	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL485_RS14305	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AL485_RS14310	COG1047	Peptidyl-prolyl cis-trans
AL485_RS14315	COG2900	Belongs to the SlyX family
AL485_RS14325	COG0545	Peptidyl-prolyl cis-trans isomerase
AL485_RS14330	COG2964	Protein conserved in bacteria
AL485_RS14335	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL485_RS14340	COG2923	Belongs to the DsrF TusC family
AL485_RS14345	COG2168	tRNA wobble position uridine thiolation
AL485_RS14350	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL485_RS14355	COG0049	tRNA binding
AL485_RS14360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL485_RS14365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL485_RS14380	COG0051	transcription antitermination factor activity, RNA binding
AL485_RS14385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL485_RS14390	COG0088	Forms part of the polypeptide exit tunnel
AL485_RS14395	COG0089	rRNA binding
AL485_RS14400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL485_RS14405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL485_RS14415	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL485_RS14420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL485_RS14425	COG0255	Belongs to the universal ribosomal protein uL29 family
AL485_RS14430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL485_RS14435	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL485_RS14440	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL485_RS14445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL485_RS14450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL485_RS14460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL485_RS14465	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL485_RS14470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL485_RS14480	COG0200	Binds to the 23S rRNA
AL485_RS14485	COG0201	protein transport
AL485_RS14490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL485_RS14495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL485_RS14500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL485_RS14505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL485_RS14510	COG0202	RNA polymerase activity
AL485_RS14515	COG0203	ribosomal protein L17
AL485_RS14525	COG0789	Transcriptional regulator
AL485_RS14530	COG3036	rescue of stalled ribosome
AL485_RS14535	COG1970	mechanosensitive ion channel activity
AL485_RS14540	COG0569	domain protein
AL485_RS14545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL485_RS14545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL485_RS14550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL485_RS14555	COG0242	peptide deformylase activity
AL485_RS14560	COG0758	DNA mediated transformation
AL485_RS14565	COG2922	Belongs to the Smg family
AL485_RS14570	COG0551	DNA topoisomerase type I activity
AL485_RS14575	COG0009	L-threonylcarbamoyladenylate synthase
AL485_RS14580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL485_RS14585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL485_RS14620	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AL485_RS14625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL485_RS14635	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AL485_RS14640	COG0800	Aldolase
AL485_RS14645	COG0129	dihydroxy-acid dehydratase activity
AL485_RS14650	COG2610	gluconate transmembrane transporter activity
AL485_RS14655	COG3265	gluconokinase activity
AL485_RS14660	COG1414	Transcriptional regulator
AL485_RS14675	COG2188	Transcriptional regulator
AL485_RS14690	COG4149	molybdate abc transporter
AL485_RS14700	COG3842	ATPase activity
AL485_RS14705	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL485_RS14725	COG0527	aspartate kinase activity
AL485_RS14735	COG0166	Belongs to the GPI family
AL485_RS14745	COG3223	Belongs to the PsiE family
AL485_RS14750	COG3833	ABC-type maltose transport systems, permease component
AL485_RS14755	COG1175	transmembrane transport
AL485_RS14760	COG2182	Extracellular solute-binding protein
AL485_RS14765	COG0366	Alpha amylase catalytic
AL485_RS14775	COG4580	involved in the transport of maltose and maltodextrins
AL485_RS14790	COG1609	Transcriptional regulator
AL485_RS14795	COG0477	Major facilitator Superfamily
AL485_RS14800	COG3161	chorismate lyase activity
AL485_RS14805	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL485_RS14810	COG2937	Belongs to the GPAT DAPAT family
AL485_RS14815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL485_RS14820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL485_RS14825	COG0534	Mate efflux family protein
AL485_RS14830	COG3237	CsbD-like
AL485_RS14835	COG0735	belongs to the Fur family
AL485_RS14845	COG1595	DNA-templated transcription, initiation
AL485_RS14855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL485_RS14870	COG0604	alcohol dehydrogenase
AL485_RS14890	COG1522	sequence-specific DNA binding
AL485_RS14895	COG1448	Aminotransferase
AL485_RS14905	COG2315	Protein conserved in bacteria
AL485_RS14910	COG0110	maltose O-acetyltransferase activity
AL485_RS14915	COG1064	alcohol dehydrogenase
AL485_RS14925	COG0629	single-stranded DNA binding
AL485_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS14935	COG0583	DNA-binding transcription factor activity
AL485_RS14945	COG0625	glutathione transferase activity
AL485_RS14955	COG2252	PERMEase
AL485_RS14960	COG0025	NhaP-type Na H and K H
AL485_RS14965	COG0583	DNA-binding transcription factor activity
AL485_RS14970	COG1380	Effector of murein hydrolase LrgA
AL485_RS14985	COG1560	Kdo2-lipid A biosynthetic process
AL485_RS15010	COG2264	protein methyltransferase activity
AL485_RS15015	COG4145	pantothenate transmembrane transporter activity
AL485_RS15020	COG3924	membrane
AL485_RS15025	COG0439	Biotin carboxylase
AL485_RS15030	COG0511	ligase activity, forming carbon-carbon bonds
AL485_RS15035	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL485_RS15040	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL485_RS15045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL485_RS15050	COG0604	alcohol dehydrogenase
AL485_RS15055	COG2199	diguanylate cyclase activity
AL485_RS15055	COG2200	EAL domain
AL485_RS15060	COG1077	Cell shape determining protein MreB Mrl
AL485_RS15065	COG1792	Involved in formation and maintenance of cell shape
AL485_RS15070	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL485_RS15075	COG0424	maF-like protein
AL485_RS15080	COG1530	ribonuclease E activity
AL485_RS15085	COG3164	Protein of unknown function
AL485_RS15090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL485_RS15095	COG0312	modulator of DNA gyrase
AL485_RS15135	COG0583	DNA-binding transcription factor activity
AL485_RS15145	COG1566	PFAM secretion protein HlyD family protein
AL485_RS15150	COG1289	transmembrane transporter activity
AL485_RS15160	COG2732	(Barnase) inhibitor
AL485_RS15165	COG3028	Belongs to the UPF0307 family
AL485_RS15170	COG0312	modulator of DNA gyrase
AL485_RS15175	COG3783	Cytochrome b(562)
AL485_RS15180	COG2207	Transcriptional regulator
AL485_RS15190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL485_RS15220	COG3964	amidohydrolase
AL485_RS15235	COG2706	6-phosphogluconolactonase activity
AL485_RS15240	COG3711	transcriptional antiterminator
AL485_RS15240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL485_RS15245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL485_RS15250	COG1660	Displays ATPase and GTPase activities
AL485_RS15265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL485_RS15270	COG1137	ATPase activity
AL485_RS15275	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL485_RS15280	COG3117	lipopolysaccharide transmembrane transporter activity
AL485_RS15285	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL485_RS15290	COG0517	IMP dehydrogenase activity
AL485_RS15290	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL485_RS15295	COG0530	calcium, potassium:sodium antiporter activity
AL485_RS15300	COG1127	ABC transporter
AL485_RS15305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL485_RS15310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL485_RS15315	COG2854	intermembrane phospholipid transfer
AL485_RS15320	COG3113	response to antibiotic
AL485_RS15325	COG5007	Belongs to the BolA IbaG family
AL485_RS15330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL485_RS15335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL485_RS15340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL485_RS15345	COG3105	Protein conserved in bacteria
AL485_RS15350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL485_RS15355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL485_RS15360	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL485_RS15365	COG0625	glutathione transferase activity
AL485_RS15370	COG2969	positive regulation of protein catabolic process
AL485_RS15380	COG0493	'glutamate synthase
AL485_RS15385	COG0067	glutamate synthase
AL485_RS15385	COG0069	glutamate synthase activity
AL485_RS15385	COG0070	glutamate synthase
AL485_RS15390	COG1242	4 iron, 4 sulfur cluster binding
AL485_RS15395	COG0784	Response regulator, receiver
AL485_RS15395	COG2198	Histidine kinase
AL485_RS15395	COG5002	protein histidine kinase activity
AL485_RS15400	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL485_RS15415	COG2823	Periplasmic or secreted lipoprotein
AL485_RS15420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL485_RS15425	COG0792	nuclease activity
AL485_RS15430	COG3107	peptidoglycan biosynthetic process
AL485_RS15435	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL485_RS15445	COG1741	Belongs to the pirin family
AL485_RS15450	COG0583	DNA-binding transcription factor activity
AL485_RS15455	COG0435	Glutathione S-transferase
AL485_RS15460	COG2259	Doxx family
AL485_RS15470	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AL485_RS15475	COG4575	ribosome binding
AL485_RS15485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL485_RS15490	COG0586	Pfam SNARE associated Golgi protein
AL485_RS15505	COG2271	Major facilitator Superfamily
AL485_RS15510	COG1904	glucuronate isomerase
AL485_RS15515	COG2721	sulfolactate sulfo-lyase activity
AL485_RS15520	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL485_RS15525	COG0861	Integral membrane protein TerC family
AL485_RS15530	COG0519	Catalyzes the synthesis of GMP from XMP
AL485_RS15530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL485_RS15535	COG0673	inositol 2-dehydrogenase activity
AL485_RS15540	COG1451	nucleotide metabolic process
AL485_RS15545	COG3093	addiction module antidote protein HigA
AL485_RS15550	COG3549	Plasmid maintenance system killer
AL485_RS15555	COG2813	Specifically methylates the guanine in position
AL485_RS15560	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL485_RS15560	COG1902	pentaerythritol trinitrate reductase activity
AL485_RS15575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL485_RS15580	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS15590	COG0625	glutathione transferase activity
AL485_RS15620	COG3663	DNA glycosylase
AL485_RS15635	COG0358	DNA primase activity
AL485_RS15640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL485_RS15645	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL485_RS15655	COG1132	(ABC) transporter
AL485_RS15655	COG2375	cellular response to nickel ion
AL485_RS15660	COG4774	siderophore transport
AL485_RS15665	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL485_RS15670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL485_RS15675	COG1968	undecaprenyl-diphosphatase activity
AL485_RS15680	COG0617	tRNA 3'-terminal CCA addition
AL485_RS15685	COG4991	sh3 domain protein
AL485_RS15690	COG3025	triphosphatase activity
AL485_RS15695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL485_RS15700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL485_RS15700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL485_RS15705	COG0531	amino acid
AL485_RS15710	COG2960	long-chain fatty acid transporting porin activity
AL485_RS15715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL485_RS15725	COG3384	dioxygenase
AL485_RS15730	COG1609	Transcriptional regulator
AL485_RS15745	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL485_RS15745	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS15750	COG3715	PTS system
AL485_RS15755	COG3716	PTS system mannose fructose sorbose family IID component
AL485_RS15765	COG2140	Oxalate decarboxylase
AL485_RS15770	COG0754	glutathionylspermidine amidase activity
AL485_RS15775	COG5463	Belongs to the UPF0441 family
AL485_RS15785	COG2376	Dihydroxyacetone kinase
AL485_RS15790	COG1461	Dihydroxyacetone kinase
AL485_RS15805	COG1312	Catalyzes the dehydration of D-mannonate
AL485_RS15810	COG1538	Outer membrane efflux protein
AL485_RS15815	COG0494	nUDIX hydrolase
AL485_RS15820	COG3151	Protein conserved in bacteria
AL485_RS15825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL485_RS15830	COG3150	esterase
AL485_RS15840	COG0583	DNA-binding transcription factor activity
AL485_RS15845	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL485_RS15850	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL485_RS15860	COG0204	Acyl-transferase
AL485_RS15865	COG2132	Multicopper oxidase
AL485_RS15870	COG0583	DNA-binding transcription factor activity
AL485_RS15875	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL485_RS15880	COG2211	Major facilitator Superfamily
AL485_RS15885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL485_RS15895	COG0741	lytic transglycosylase activity
AL485_RS15900	COG1940	carbohydrate kinase activity
AL485_RS15905	COG0457	Tetratricopeptide repeat
AL485_RS15910	COG2814	Major facilitator Superfamily
AL485_RS15910	COG0477	Major facilitator Superfamily
AL485_RS15915	COG1879	ABC-type sugar transport system periplasmic component
AL485_RS15920	COG1129	ABC transporter
AL485_RS15925	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS15930	COG1063	alcohol dehydrogenase
AL485_RS15935	COG2017	converts alpha-aldose to the beta-anomer
AL485_RS15945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL485_RS15950	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL485_RS15955	COG2723	6-phospho-beta-galactosidase activity
AL485_RS15965	COG0402	S-adenosylhomocysteine deaminase activity
AL485_RS15970	COG0656	L-ascorbic acid biosynthetic process
AL485_RS15975	COG1979	alcohol dehydrogenase
AL485_RS15980	COG2207	Transcriptional regulator
AL485_RS15985	COG0604	alcohol dehydrogenase
AL485_RS15985	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS15985	COG3321	synthase
AL485_RS15990	COG0583	DNA-binding transcription factor activity
AL485_RS15995	COG0586	Pfam SNARE associated Golgi protein
AL485_RS16010	COG0848	biopolymer transport protein
AL485_RS16015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL485_RS16045	COG2831	hemolysin activation secretion protein
AL485_RS16050	COG2994	toxin metabolic process
AL485_RS16075	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL485_RS16080	COG1473	amidohydrolase
AL485_RS16085	COG1473	amidohydrolase
AL485_RS16090	COG0583	DNA-binding transcription factor activity
AL485_RS16095	COG4772	TonB-dependent receptor
AL485_RS16110	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL485_RS16110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL485_RS16135	COG0454	-acetyltransferase
AL485_RS16175	COG2003	Belongs to the UPF0758 family
AL485_RS16190	COG0859	PFAM glycosyl transferase family 9
AL485_RS16225	COG2378	regulation of single-species biofilm formation
AL485_RS16230	COG3596	GTP binding
AL485_RS16295	COG0791	NLP P60 protein
AL485_RS16305	COG3753	Protein conserved in bacteria
AL485_RS16330	COG0582	viral genome integration into host DNA
AL485_RS16355	COG3121	Chaperone
AL485_RS16360	COG3121	Chaperone
AL485_RS16365	COG3188	usher protein
AL485_RS16445	COG4974	Belongs to the 'phage' integrase family
AL485_RS16455	COG3436	PFAM IS66 Orf2 family protein
AL485_RS16485	COG0582	viral genome integration into host DNA
AL485_RS16495	COG1982	Orn Lys Arg decarboxylase major
AL485_RS16500	COG0741	lytic transglycosylase activity
AL485_RS16505	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL485_RS16515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL485_RS16520	COG3171	Protein conserved in bacteria
AL485_RS16525	COG2066	Belongs to the glutaminase family
AL485_RS16545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL485_RS16550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL485_RS16555	COG1872	DUF167
AL485_RS16560	COG0762	integral membrane protein
AL485_RS16565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL485_RS16570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL485_RS16575	COG2805	Type II/IV secretion system protein
AL485_RS16580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL485_RS16585	COG1678	Uncharacterized ACR, COG1678
AL485_RS16590	COG0189	ligase activity
AL485_RS16595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL485_RS16600	COG2356	endonuclease I
AL485_RS16605	COG3091	SprT-like family
AL485_RS16610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL485_RS16610	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL485_RS16615	COG2207	Transcriptional regulator
AL485_RS16615	COG3708	Transcriptional regulator
AL485_RS16620	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AL485_RS16630	COG2010	Cytochrome c
AL485_RS16630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL485_RS16640	COG2010	Cytochrome c
AL485_RS16640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL485_RS16645	COG1113	amino acid transport
AL485_RS16650	COG2186	Transcriptional regulator
AL485_RS16655	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL485_RS16660	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL485_RS16665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL485_RS16675	COG3112	Uncharacterised protein family (UPF0231)
AL485_RS16680	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AL485_RS16685	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL485_RS16695	COG2132	Multicopper oxidase
AL485_RS16705	COG0288	reversible hydration of carbon dioxide
AL485_RS16710	COG1131	(ABC) transporter
AL485_RS16715	COG0842	Transport permease protein
AL485_RS16720	COG0726	polysaccharide deacetylase
AL485_RS16725	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL485_RS16730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL485_RS16740	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL485_RS16750	COG0642	Histidine kinase
AL485_RS16755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL485_RS16760	COG0617	tRNA 3'-terminal CCA addition
AL485_RS16765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL485_RS16780	COG1489	DNA binding
AL485_RS16785	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AL485_RS16790	COG1643	Atp-dependent helicase
AL485_RS16795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL485_RS16800	COG4774	siderophore transport
AL485_RS16805	COG1120	ATPase activity
AL485_RS16810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL485_RS16815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL485_RS16825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL485_RS16830	COG1166	arginine decarboxylase activity
AL485_RS16845	COG0010	Belongs to the arginase family
AL485_RS16850	COG1187	pseudouridine synthase activity
AL485_RS16855	COG2271	Major facilitator Superfamily
AL485_RS16860	COG2146	nitrite reductase [NAD(P)H] activity
AL485_RS16880	COG1414	Transcriptional regulator
AL485_RS16895	COG2271	Major facilitator Superfamily
AL485_RS16905	COG2267	carboxylic ester hydrolase activity
AL485_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS16915	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AL485_RS16930	COG0501	Belongs to the peptidase M48B family
AL485_RS16935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL485_RS16945	COG1175	transmembrane transport
AL485_RS16950	COG3842	ATPase activity
AL485_RS16955	COG0473	3-isopropylmalate dehydrogenase activity
AL485_RS16960	COG0583	DNA-binding transcription factor activity
AL485_RS16965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL485_RS16970	COG0126	phosphoglycerate kinase activity
AL485_RS16975	COG0191	fructose-bisphosphate aldolase activity
AL485_RS16990	COG2271	Major facilitator Superfamily
AL485_RS17000	COG0235	Class ii aldolase
AL485_RS17005	COG3623	hexulose-6-phosphate isomerase
AL485_RS17010	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AL485_RS17015	COG1070	Carbohydrate kinase
AL485_RS17025	COG2731	YhcH YjgK YiaL family protein
AL485_RS17045	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS17050	COG1129	ABC transporter
AL485_RS17055	COG1414	Transcriptional regulator
AL485_RS17060	COG1279	arginine transmembrane transporter activity
AL485_RS17075	COG0583	DNA-binding transcription factor activity
AL485_RS17080	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AL485_RS17085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL485_RS17090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL485_RS17100	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL485_RS17105	COG3079	Belongs to the UPF0149 family
AL485_RS17110	COG0006	proline dipeptidase activity
AL485_RS17115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL485_RS17120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL485_RS17130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL485_RS17135	COG0509	glycine decarboxylation via glycine cleavage system
AL485_RS17140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL485_RS17140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL485_RS17180	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS17215	COG1272	protein, Hemolysin III
AL485_RS17225	COG0354	folic acid binding
AL485_RS17230	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL485_RS17240	COG0745	RESPONSE REGULATOR receiver
AL485_RS17245	COG2205	protein histidine kinase activity
AL485_RS17250	COG4452	Inner membrane protein CreD
AL485_RS17255	COG0716	FMN binding
AL485_RS17260	COG4974	Belongs to the 'phage' integrase family
AL485_RS17265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL485_RS17270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL485_RS17280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL485_RS17330	COG3539	Fimbrial protein
AL485_RS17335	COG3121	Chaperone
AL485_RS17340	COG3188	usher protein
AL485_RS17350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL485_RS17360	COG2186	Transcriptional regulator
AL485_RS17370	COG2197	response regulator
AL485_RS17390	COG0484	heat shock protein binding
AL485_RS17395	COG3247	response to pH
AL485_RS17400	COG0583	DNA-binding transcription factor activity
AL485_RS17405	COG1335	isochorismatase
AL485_RS17410	COG5265	(ABC) transporter
AL485_RS17415	COG1942	4-Oxalocrotonate Tautomerase
AL485_RS17425	COG1304	FMN binding
AL485_RS17430	COG1620	l-lactate permease
AL485_RS17440	COG4615	Cyclic peptide transporter
AL485_RS17450	COG2807	transmembrane transport
AL485_RS17455	COG1349	DNA-binding transcription factor activity
AL485_RS17465	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS17470	COG3715	PTS system
AL485_RS17475	COG3716	PTS system mannose fructose sorbose family IID component
AL485_RS17485	COG4178	(ABC) transporter
AL485_RS17505	COG0583	DNA-binding transcription factor activity
AL485_RS17510	COG2814	Major facilitator Superfamily
AL485_RS17515	COG0583	DNA-binding transcription factor activity
AL485_RS17535	COG1609	Transcriptional regulator
AL485_RS17545	COG1609	Transcriptional regulator
AL485_RS17555	COG0204	Acyl-transferase
AL485_RS17555	COG0318	PFAM AMP-dependent synthetase and ligase
AL485_RS17560	COG0477	Major facilitator Superfamily
AL485_RS17565	COG0667	Aldo Keto reductase
AL485_RS17575	COG0861	Integral membrane protein TerC family
AL485_RS17580	COG3066	DNA modification
AL485_RS17590	COG0494	nUDIX hydrolase
AL485_RS17600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AL485_RS17605	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL485_RS17630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL485_RS17635	COG1025	Belongs to the peptidase M16 family
AL485_RS17640	COG1074	ATP-dependent DNA helicase activity
AL485_RS17645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL485_RS17650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL485_RS17650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL485_RS17655	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL485_RS17680	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL485_RS17685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL485_RS17690	COG2166	iron-sulfur cluster assembly
AL485_RS17695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL485_RS17705	COG0583	DNA-binding transcription factor activity
AL485_RS17710	COG2363	Small membrane protein
AL485_RS17715	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AL485_RS17720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL485_RS17725	COG1611	Belongs to the LOG family
AL485_RS17745	COG3098	single-species biofilm formation
AL485_RS17750	COG2373	Large extracellular alpha-helical protein
AL485_RS17755	COG4953	penicillin-binding protein 1C
AL485_RS17760	COG0564	pseudouridine synthase activity
AL485_RS17780	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL485_RS17795	COG0052	Belongs to the universal ribosomal protein uS2 family
AL485_RS17800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL485_RS17805	COG0528	UMP kinase activity
AL485_RS17810	COG0233	cytoplasmic translational termination
AL485_RS17815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL485_RS17820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL485_RS17825	COG0575	Belongs to the CDS family
AL485_RS17830	COG0750	zinc metalloprotease
AL485_RS17835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL485_RS17840	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL485_RS17845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL485_RS17850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL485_RS17855	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL485_RS17860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL485_RS17865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL485_RS17875	COG0825	malonyl-CoA metabolic process
AL485_RS17880	COG1982	Orn Lys Arg decarboxylase major
AL485_RS17895	COG0346	lactoylglutathione lyase activity
AL485_RS17900	COG3710	Transcriptional regulator
AL485_RS17905	COG0531	amino acid
AL485_RS17915	COG3104	oligopeptide transport
AL485_RS17920	COG0037	tRNA processing
AL485_RS17930	COG4568	rho-dependent transcription termination
AL485_RS17945	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL485_RS17950	COG3015	lipoprotein NlpE involved in copper resistance
AL485_RS17955	COG0442	prolyl-tRNA aminoacylation
AL485_RS17960	COG1720	tRNA m6t6A37 methyltransferase activity
AL485_RS17975	COG2011	ABC-type metal ion transport system permease component
AL485_RS17985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL485_RS18015	COG0477	Major facilitator Superfamily
AL485_RS18020	COG5544	Lipoprotein
AL485_RS18025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL485_RS18030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL485_RS18030	COG0045	succinate-CoA ligase (ADP-forming) activity
AL485_RS18030	COG1042	CoA-binding domain protein
AL485_RS18035	COG3148	PFAM DTW domain containing protein
AL485_RS18040	COG3118	belongs to the thioredoxin family
AL485_RS18045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL485_RS18050	COG2814	Major facilitator Superfamily
AL485_RS18055	COG1566	PFAM secretion protein HlyD family protein
AL485_RS18060	COG1538	Outer membrane efflux protein
AL485_RS18065	COG1846	Transcriptional regulator
AL485_RS18075	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AL485_RS18080	COG2814	Major facilitator Superfamily
AL485_RS18085	COG0583	DNA-binding transcription factor activity
AL485_RS18090	COG2113	Glycine betaine
AL485_RS18095	COG2113	Glycine betaine
AL485_RS18100	COG4176	ABC-type proline glycine betaine transport system permease component
AL485_RS18105	COG4175	Glycine betaine
AL485_RS18120	COG3493	citrate carrier protein
AL485_RS18135	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS18155	COG1780	Probably involved in ribonucleotide reductase function
AL485_RS18160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL485_RS18165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL485_RS18175	COG4575	ribosome binding
AL485_RS18195	COG0583	DNA-binding transcription factor activity
AL485_RS18205	COG3708	Transcriptional regulator
AL485_RS18205	COG2207	Transcriptional regulator
AL485_RS18225	COG2840	Smr protein MutS2
AL485_RS18230	COG2259	Doxx family
AL485_RS18235	COG2388	GCN5-related N-acetyl-transferase
AL485_RS18245	COG2226	methyltransferase
AL485_RS18260	COG3713	MltA-interacting MipA family protein
AL485_RS18265	COG0583	DNA-binding transcription factor activity
AL485_RS18280	COG1566	PFAM secretion protein HlyD family protein
AL485_RS18295	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS18330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL485_RS18335	COG2867	negative regulation of translational initiation
AL485_RS18340	COG2914	Belongs to the UPF0125 (RnfH) family
AL485_RS18350	COG0497	DNA recombination
AL485_RS18355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL485_RS18360	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL485_RS18365	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL485_RS18370	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AL485_RS18385	COG0513	Belongs to the DEAD box helicase family
AL485_RS18390	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AL485_RS18395	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL485_RS18410	COG3026	antisigma factor binding
AL485_RS18415	COG3086	response to oxidative stress
AL485_RS18445	COG3561	AntA/AntB antirepressor
AL485_RS18550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL485_RS18760	COG0481	GTPase activity
AL485_RS18765	COG0681	Belongs to the peptidase S26 family
AL485_RS18770	COG0571	ribonuclease III activity
AL485_RS18775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL485_RS18780	COG1381	Involved in DNA repair and RecF pathway recombination
AL485_RS18785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL485_RS18790	COG0736	holo-[acyl-carrier-protein] synthase activity
AL485_RS18795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL485_RS18805	COG1737	Transcriptional regulator
AL485_RS18810	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL485_RS18815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS18815	COG1263	PTS System
AL485_RS18820	COG0560	Phosphoserine phosphatase
AL485_RS18825	COG1454	alcohol dehydrogenase
AL485_RS18840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL485_RS18850	COG2205	protein histidine kinase activity
AL485_RS18855	COG3170	Tfp pilus assembly protein FimV
AL485_RS18860	COG2204	response regulator
AL485_RS18865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL485_RS18865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL485_RS18870	COG0347	Belongs to the P(II) protein family
AL485_RS18890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL485_RS18895	COG3842	ATPase activity
AL485_RS18900	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL485_RS18905	COG1177	transmembrane transport
AL485_RS18910	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS18915	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AL485_RS18925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL485_RS18925	COG1017	nitric oxide dioxygenase activity
AL485_RS18930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL485_RS18935	COG2814	Major facilitator Superfamily
AL485_RS18940	COG3711	transcriptional antiterminator
AL485_RS18945	COG3683	transport system, periplasmic component
AL485_RS18950	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL485_RS18965	COG1959	2 iron, 2 sulfur cluster binding
AL485_RS18970	COG1104	cysteine desulfurase activity
AL485_RS18975	COG0822	iron-sulfur transferase activity
AL485_RS18980	COG0316	Belongs to the HesB IscA family
AL485_RS18985	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL485_RS18990	COG0443	Heat shock 70 kDa protein
AL485_RS18995	COG0633	Ferredoxin
AL485_RS19000	COG2975	iron-sulfur cluster assembly
AL485_RS19005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL485_RS19015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL485_RS19020	COG1757	Na H antiporter
AL485_RS19025	COG1609	Transcriptional regulator
AL485_RS19030	COG0105	UTP biosynthetic process
AL485_RS19035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL485_RS19045	COG1426	Protein conserved in bacteria
AL485_RS19050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL485_RS19055	COG0124	histidyl-tRNA synthetase
AL485_RS19060	COG2976	Protein conserved in bacteria
AL485_RS19065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL485_RS19070	COG1160	GTP binding
AL485_RS19100	COG2271	Major facilitator Superfamily
AL485_RS19110	COG1570	exodeoxyribonuclease VII activity
AL485_RS19120	COG0516	GMP reductase activity
AL485_RS19120	COG0517	IMP dehydrogenase activity
AL485_RS19125	COG0519	Catalyzes the synthesis of GMP from XMP
AL485_RS19125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL485_RS19145	COG1733	regulation of RNA biosynthetic process
AL485_RS19155	COG2198	Histidine kinase
AL485_RS19155	COG0784	Response regulator, receiver
AL485_RS19155	COG2205	protein histidine kinase activity
AL485_RS19160	COG2197	response regulator
AL485_RS19195	COG2814	Major facilitator Superfamily
AL485_RS19200	COG2188	Transcriptional regulator
AL485_RS19205	COG1082	Xylose isomerase domain protein TIM barrel
AL485_RS19210	COG2271	Major facilitator Superfamily
AL485_RS19220	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AL485_RS19225	COG0351	phosphomethylpyrimidine kinase
AL485_RS19245	COG1349	DNA-binding transcription factor activity
AL485_RS19250	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL485_RS19255	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS19270	COG3730	PTS system glucitol sorbitol-specific
AL485_RS19275	COG1830	Aldolase
AL485_RS19280	COG1802	Transcriptional regulator
AL485_RS19285	COG0246	Mannitol dehydrogenase
AL485_RS19290	COG2271	Major facilitator Superfamily
AL485_RS19300	COG1063	alcohol dehydrogenase
AL485_RS19305	COG4948	Mandelate Racemase Muconate Lactonizing
AL485_RS19310	COG1597	lipid kinase activity
AL485_RS19315	COG0826	peptidase U32
AL485_RS19320	COG3422	double-strand break repair
AL485_RS19335	COG0745	RESPONSE REGULATOR receiver
AL485_RS19340	COG2205	protein histidine kinase activity
AL485_RS19345	COG2814	Major facilitator Superfamily
AL485_RS19350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL485_RS19355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL485_RS19360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS19365	COG0667	Aldo Keto reductase
AL485_RS19375	COG0443	Heat shock 70 kDa protein
AL485_RS19380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL485_RS19390	COG5002	protein histidine kinase activity
AL485_RS19390	COG5001	Diguanylate cyclase
AL485_RS19390	COG3447	MASE1 domain protein
AL485_RS19395	COG2239	Acts as a magnesium transporter
AL485_RS19405	COG2200	EAL domain
AL485_RS19415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL485_RS19420	COG0573	inorganic phosphate transmembrane transporter activity
AL485_RS19425	COG0573	inorganic phosphate transmembrane transporter activity
AL485_RS19470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL485_RS19475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL485_RS19480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL485_RS19490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL485_RS19495	COG2233	PERMEase
AL485_RS19500	COG2261	transglycosylase associated protein
AL485_RS19510	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL485_RS19515	COG1393	Belongs to the ArsC family
AL485_RS19520	COG4783	chaperone-mediated protein folding
AL485_RS19555	COG2005	Transcriptional regulator
AL485_RS19555	COG3585	molybdate ion transport
AL485_RS19570	COG0628	permease
AL485_RS19575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL485_RS19580	COG2716	regulation of RNA biosynthetic process
AL485_RS19585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL485_RS19590	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL485_RS19595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL485_RS19600	COG2321	neutral zinc metallopeptidase
AL485_RS19605	COG1444	tRNA N-acetyltransferase activity
AL485_RS19610	COG0400	carboxylic ester hydrolase activity
AL485_RS19620	COG1876	peptidase activity
AL485_RS19625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL485_RS19630	COG1393	Belongs to the ArsC family
AL485_RS19645	COG0456	acetyltransferase
AL485_RS19665	COG4771	TonB-dependent receptor
AL485_RS19675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL485_RS19685	COG2197	response regulator
AL485_RS19690	COG3850	Histidine kinase
AL485_RS19695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL485_RS19695	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL485_RS19700	COG3062	negative regulation of establishment of protein localization
AL485_RS19705	COG0243	molybdopterin cofactor binding
AL485_RS19710	COG3043	anaerobic respiration
AL485_RS19715	COG3005	denitrification pathway
AL485_RS19720	COG0494	nUDIX hydrolase
AL485_RS19725	COG3708	Transcriptional regulator
AL485_RS19725	COG2207	Transcriptional regulator
AL485_RS19730	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AL485_RS19735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL485_RS19740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL485_RS19745	COG3397	chitin binding
AL485_RS19750	COG0583	DNA-binding transcription factor activity
AL485_RS19780	COG2040	homocysteine
AL485_RS19785	COG0833	amino acid
AL485_RS19800	COG1770	oligopeptidase
AL485_RS19810	COG1671	Belongs to the UPF0178 family
AL485_RS19815	COG0408	coproporphyrinogen oxidase activity
AL485_RS19825	COG0456	acetyltransferase
AL485_RS19830	COG3111	PFAM Bacterial OB fold (BOF) protein
AL485_RS19845	COG2837	iron assimilation
AL485_RS19850	COG4150	thiosulfate binding
AL485_RS19855	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL485_RS19860	COG4208	sulfate ABC transporter
AL485_RS19870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL485_RS19880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS19885	COG0745	RESPONSE REGULATOR receiver
AL485_RS19890	COG2205	protein histidine kinase activity
AL485_RS19900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL485_RS19905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL485_RS19915	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AL485_RS19920	COG3115	cell septum assembly
AL485_RS19925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL485_RS19930	COG3530	Putative quorum-sensing-regulated virulence factor
AL485_RS19935	COG0385	Bile acid
AL485_RS19940	COG0583	DNA-binding transcription factor activity
AL485_RS19955	COG4303	Ethanolamine ammonia lyase large subunit
AL485_RS19960	COG4302	ethanolamine ammonia-lyase activity
AL485_RS19980	COG0747	negative chemotaxis
AL485_RS19985	COG4771	TonB-dependent receptor
AL485_RS19990	COG2382	esterase
AL485_RS19995	COG3251	PFAM MbtH domain protein
AL485_RS20000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL485_RS20000	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AL485_RS20005	COG1120	ATPase activity
AL485_RS20010	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL485_RS20015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL485_RS20025	COG4592	Periplasmic binding protein
AL485_RS20030	COG1169	isochorismate synthase
AL485_RS20035	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL485_RS20040	COG1535	isochorismatase
AL485_RS20040	COG3433	isochorismatase activity
AL485_RS20045	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS20075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL485_RS20080	COG2116	formate transmembrane transporter activity
AL485_RS20095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL485_RS20100	COG1914	H( )-stimulated, divalent metal cation uptake system
AL485_RS20110	COG0667	Aldo Keto reductase
AL485_RS20115	COG3961	Belongs to the TPP enzyme family
AL485_RS20130	COG1794	racemase activity, acting on amino acids and derivatives
AL485_RS20145	COG2223	nitrite transmembrane transporter activity
AL485_RS20155	COG3279	Response regulator of the LytR AlgR family
AL485_RS20160	COG3275	phosphorelay sensor kinase activity
AL485_RS20175	COG0436	Aminotransferase
AL485_RS20180	COG3038	cytochrome b561
AL485_RS20190	COG1598	PFAM Uncharacterised protein family UPF0150
AL485_RS20200	COG2951	lytic endotransglycosylase activity
AL485_RS20215	COG0697	spore germination
AL485_RS20225	COG0583	DNA-binding transcription factor activity
AL485_RS20230	COG3122	Protein conserved in bacteria
AL485_RS20240	COG2116	formate transmembrane transporter activity
AL485_RS20250	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL485_RS20255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL485_RS20260	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL485_RS20265	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL485_RS20270	COG1138	Cytochrome C-type biogenesis protein
AL485_RS20275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL485_RS20280	COG3088	subunit of a heme lyase
AL485_RS20280	COG4235	cytochrome complex assembly
AL485_RS20285	COG3088	subunit of a heme lyase
AL485_RS20285	COG4235	cytochrome complex assembly
AL485_RS20300	COG3691	Protein conserved in bacteria
AL485_RS20305	COG0183	Belongs to the thiolase family
AL485_RS20310	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL485_RS20310	COG1024	Enoyl-CoA hydratase
AL485_RS20315	COG2062	phosphohistidine phosphatase, SixA
AL485_RS20320	COG2840	Smr protein MutS2
AL485_RS20325	COG2890	protein-(glutamine-N5) methyltransferase activity
AL485_RS20330	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL485_RS20335	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AL485_RS20340	COG0730	response to heat
AL485_RS20345	COG3101	peptidyl-lysine hydroxylation
AL485_RS20355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL485_RS20355	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL485_RS20360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL485_RS20385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS20390	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL485_RS20395	COG1477	protein flavinylation
AL485_RS20400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL485_RS20405	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL485_RS20445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL485_RS20450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL485_RS20490	COG0642	Histidine kinase
AL485_RS20495	COG0697	spore germination
AL485_RS20505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL485_RS20510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL485_RS20520	COG0586	Pfam SNARE associated Golgi protein
AL485_RS20525	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL485_RS20530	COG0285	dihydrofolate synthase activity
AL485_RS20535	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL485_RS20540	COG1286	toxin biosynthetic process
AL485_RS20545	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL485_RS20550	COG0163	prenyltransferase activity
AL485_RS20555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL485_RS20560	COG4215	(ABC) transporter
AL485_RS20570	COG4598	ABC transporter
AL485_RS20575	COG1090	epimerase
AL485_RS20580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL485_RS20585	COG0625	glutathione transferase activity
AL485_RS20590	COG0622	Phosphoesterase
AL485_RS20595	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AL485_RS20600	COG0857	belongs to the CobB CobQ family
AL485_RS20600	COG0280	phosphate acetyltransferase
AL485_RS20605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL485_RS20610	COG3092	negative regulation of chromosome organization
AL485_RS20615	COG3013	Belongs to the UPF0304 family
AL485_RS20620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL485_RS20625	COG0490	domain, Protein
AL485_RS20625	COG0471	metal ion transport
AL485_RS20630	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL485_RS20635	COG0436	Aminotransferase
AL485_RS20640	COG0583	DNA-binding transcription factor activity
AL485_RS20645	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL485_RS20650	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL485_RS20655	COG0649	NAD binding
AL485_RS20655	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL485_RS20670	COG1034	ATP synthesis coupled electron transport
AL485_RS20675	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL485_RS20685	COG0839	Belongs to the complex I subunit 6 family
AL485_RS20690	COG0713	ATP synthesis coupled electron transport
AL485_RS20695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL485_RS20700	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL485_RS20705	COG1007	ATP synthesis coupled electron transport
AL485_RS20715	COG0028	Belongs to the TPP enzyme family
AL485_RS20740	COG1609	Transcriptional regulator
AL485_RS20745	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS20750	COG1063	alcohol dehydrogenase
AL485_RS20755	COG4575	ribosome binding
AL485_RS20760	COG3459	Glycosyltransferase 36 associated
AL485_RS20765	COG1169	isochorismate synthase
AL485_RS20770	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AL485_RS20775	COG0596	Alpha beta hydrolase
AL485_RS20780	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL485_RS20805	COG0814	amino acid
AL485_RS20815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL485_RS20820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL485_RS20830	COG2721	sulfolactate sulfo-lyase activity
AL485_RS20840	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS20845	COG1063	alcohol dehydrogenase
AL485_RS20850	COG2271	Major facilitator Superfamily
AL485_RS20855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL485_RS20855	COG0473	3-isopropylmalate dehydrogenase activity
AL485_RS20865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL485_RS20875	COG0784	Response regulator, receiver
AL485_RS20875	COG2205	protein histidine kinase activity
AL485_RS20885	COG2198	Histidine kinase
AL485_RS20885	COG0642	Histidine kinase
AL485_RS20890	COG2223	nitrite transmembrane transporter activity
AL485_RS20905	COG0346	lactoylglutathione lyase activity
AL485_RS20940	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL485_RS20975	COG3082	Protein of unknown function (DUF1414)
AL485_RS20980	COG3081	Nucleoid-associated protein
AL485_RS20985	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL485_RS20990	COG1061	Type III restriction enzyme res subunit
AL485_RS20995	COG1187	pseudouridine synthase activity
AL485_RS21000	COG2814	Major facilitator Superfamily
AL485_RS21010	COG4172	Belongs to the ABC transporter superfamily
AL485_RS21015	COG4239	(ABC) transporter, permease
AL485_RS21020	COG4174	ABC transporter (Permease)
AL485_RS21025	COG4166	transmembrane transport
AL485_RS21030	COG2200	EAL domain
AL485_RS21035	COG0791	NLP P60 protein
AL485_RS21045	COG0671	phosphoesterase, PA-phosphatase related
AL485_RS21050	COG0523	cobalamin synthesis protein
AL485_RS21060	COG0246	Mannitol dehydrogenase
AL485_RS21065	COG1312	Catalyzes the dehydration of D-mannonate
AL485_RS21070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL485_RS21090	COG0243	molybdopterin cofactor binding
AL485_RS21095	COG3005	denitrification pathway
AL485_RS21100	COG0494	nUDIX hydrolase
AL485_RS21110	COG1105	Belongs to the carbohydrate kinase PfkB family
AL485_RS21115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL485_RS21115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL485_RS21115	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL485_RS21120	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AL485_RS21125	COG2855	membrane
AL485_RS21130	COG0583	DNA-binding transcription factor activity
AL485_RS21135	COG0833	amino acid
AL485_RS21145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL485_RS21160	COG4771	TonB-dependent receptor
AL485_RS21165	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL485_RS21170	COG1129	ABC transporter
AL485_RS21175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL485_RS21180	COG1917	Cupin 2, conserved barrel domain protein
AL485_RS21180	COG1396	sequence-specific DNA binding
AL485_RS21185	COG0174	glutamine synthetase
AL485_RS21195	COG0531	amino acid
AL485_RS21200	COG2925	Exonuclease
AL485_RS21225	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL485_RS21230	COG1289	transmembrane transporter activity
AL485_RS21235	COG2926	Belongs to the UPF0265 family
AL485_RS21240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL485_RS21245	COG1473	amidohydrolase
AL485_RS21280	COG0411	ABC transporter
AL485_RS21295	COG1609	Transcriptional regulator
AL485_RS21300	COG0673	inositol 2-dehydrogenase activity
AL485_RS21305	COG1082	Xylose isomerase domain protein TIM barrel
AL485_RS21315	COG2271	Major facilitator Superfamily
AL485_RS21320	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AL485_RS21330	COG4122	O-methyltransferase activity
AL485_RS21340	COG3250	beta-galactosidase activity
AL485_RS21345	COG4565	transcriptional regulatory protein
AL485_RS21350	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AL485_RS21355	COG3052	prosthetic group binding
AL485_RS21360	COG2301	Belongs to the HpcH HpaI aldolase family
AL485_RS21365	COG3051	citrate lyase alpha subunit
AL485_RS21380	COG0471	metal ion transport
AL485_RS21390	COG2977	Belongs to the P-Pant transferase superfamily
AL485_RS21410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL485_RS21420	COG0747	negative chemotaxis
AL485_RS21425	COG0601	transmembrane transport
AL485_RS21430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL485_RS21435	COG4172	Belongs to the ABC transporter superfamily
AL485_RS21440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL485_RS21455	COG0583	DNA-binding transcription factor activity
AL485_RS21480	COG3238	Protein conserved in bacteria
AL485_RS21495	COG0583	DNA-binding transcription factor activity
AL485_RS21535	COG0642	Histidine kinase
AL485_RS21545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS21560	COG3781	membrane
AL485_RS21565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL485_RS21580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL485_RS21585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL485_RS21590	COG1116	anion transmembrane transporter activity
AL485_RS21595	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL485_RS21600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL485_RS21605	COG4977	sequence-specific DNA binding
AL485_RS21610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL485_RS21620	COG3842	ATPase activity
AL485_RS21630	COG1840	ABC-type Fe3 transport system, periplasmic component
AL485_RS21635	COG1609	Transcriptional regulator
AL485_RS21665	COG0583	DNA-binding transcription factor activity
AL485_RS21670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL485_RS21680	COG3228	Belongs to the MtfA family
AL485_RS21690	COG4977	sequence-specific DNA binding
AL485_RS21695	COG1335	isochorismatase
AL485_RS21730	COG0795	lipopolysaccharide-transporting ATPase activity
AL485_RS21735	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL485_RS21745	COG2244	polysaccharide biosynthetic process
AL485_RS21750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL485_RS21755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL485_RS21760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL485_RS21765	COG0156	8-amino-7-oxononanoate synthase activity
AL485_RS21770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL485_RS21785	COG0456	acetyltransferase
AL485_RS21795	COG0534	Mate efflux family protein
AL485_RS21805	COG1486	melibiose metabolic process
AL485_RS21810	COG2223	nitrite transmembrane transporter activity
AL485_RS21820	COG4993	Dehydrogenase
AL485_RS21825	COG0667	Aldo Keto reductase
AL485_RS21855	COG0625	glutathione transferase activity
AL485_RS21860	COG0583	DNA-binding transcription factor activity
AL485_RS21880	COG1113	amino acid transport
AL485_RS21885	COG0697	spore germination
AL485_RS21895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL485_RS21900	COG3327	negative regulation of DNA-templated transcription, initiation
AL485_RS21905	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AL485_RS21910	COG0183	Belongs to the thiolase family
AL485_RS21915	COG2050	protein possibly involved in aromatic compounds catabolism
AL485_RS21920	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL485_RS21925	COG1024	Enoyl-CoA hydratase
AL485_RS21930	COG1024	Enoyl-CoA hydratase
AL485_RS21935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL485_RS21940	COG2151	metal-sulfur cluster biosynthetic enzyme
AL485_RS21945	COG3396	Phenylacetate-CoA oxygenase
AL485_RS21950	COG3460	Phenylacetate-CoA oxygenase
AL485_RS21955	COG3396	Phenylacetate-CoA oxygenase
AL485_RS21960	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS21960	COG2030	dehydratase
AL485_RS21965	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL485_RS21975	COG5001	Diguanylate cyclase
AL485_RS21975	COG4251	negative regulation of phosphorylation
AL485_RS21975	COG3706	GGDEF domain
AL485_RS21975	COG2203	Gaf domain
AL485_RS21985	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL485_RS21990	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS21995	COG0583	DNA-binding transcription factor activity
AL485_RS22000	COG2261	transglycosylase associated protein
AL485_RS22005	COG3753	Protein conserved in bacteria
AL485_RS22025	COG3321	synthase
AL485_RS22025	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS22025	COG0604	alcohol dehydrogenase
AL485_RS22040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL485_RS22060	COG0076	glutamate decarboxylase activity
AL485_RS22070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL485_RS22080	COG1285	pathogenesis
AL485_RS22125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL485_RS22135	COG0431	NADPH-dependent FMN reductase
AL485_RS22140	COG2837	iron assimilation
AL485_RS22165	COG0156	8-amino-7-oxononanoate synthase activity
AL485_RS22175	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AL485_RS22180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL485_RS22195	COG3483	tryptophan 2,3-dioxygenase activity
AL485_RS22200	COG0583	DNA-binding transcription factor activity
AL485_RS22205	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL485_RS22210	COG2130	NADP-dependent
AL485_RS22250	COG2198	Histidine kinase
AL485_RS22250	COG0643	Histidine kinase
AL485_RS22255	COG0835	chemotaxis
AL485_RS22260	COG0840	transmembrane signaling receptor activity
AL485_RS22265	COG0840	transmembrane signaling receptor activity
AL485_RS22270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL485_RS22285	COG0745	RESPONSE REGULATOR receiver
AL485_RS22290	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL485_RS22295	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL485_RS22300	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL485_RS22315	COG0583	DNA-binding transcription factor activity
AL485_RS22325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL485_RS22335	COG3418	PFAM FlgN family protein
AL485_RS22340	COG2747	anti-sigma28 factor FlgM
AL485_RS22350	COG1815	bacterial-type flagellum-dependent cell motility
AL485_RS22355	COG1558	bacterial-type flagellum-dependent cell motility
AL485_RS22360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL485_RS22395	COG1256	bacterial-type flagellum assembly
AL485_RS22410	COG1987	bacterial-type flagellum assembly
AL485_RS22435	COG1580	Controls the rotational direction of flagella during chemotaxis
AL485_RS22445	COG2882	bacterial-type flagellum organization
AL485_RS22450	COG1157	protein secretion by the type III secretion system
AL485_RS22455	COG1317	bacterial-type flagellum organization
AL485_RS22460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL485_RS22470	COG1677	Flagellar hook-basal body complex protein FliE
AL485_RS22505	COG1191	sigma factor activity
AL485_RS22515	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL485_RS22520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL485_RS22525	COG0765	amino acid transport
AL485_RS22530	COG1126	abc transporter atp-binding protein
AL485_RS22545	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL485_RS22545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL485_RS22545	COG0506	proline dehydrogenase activity
AL485_RS22555	COG0672	)-iron permease
AL485_RS22560	COG2822	iron ion transport
AL485_RS22570	COG4772	TonB-dependent receptor
AL485_RS22575	COG1702	phosphate starvation-inducible protein PhoH
AL485_RS22585	COG0437	4 iron, 4 sulfur cluster binding
AL485_RS22590	COG0243	molybdopterin cofactor binding
AL485_RS22600	COG0387	Pfam Sodium calcium exchanger
AL485_RS22610	COG4572	Cation transport regulator
AL485_RS22615	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AL485_RS22620	COG0583	DNA-binding transcription factor activity
AL485_RS22630	COG4166	transmembrane transport
AL485_RS22635	COG0601	transmembrane transport
AL485_RS22640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL485_RS22645	COG0444	Belongs to the ABC transporter superfamily
AL485_RS22650	COG4608	Belongs to the ABC transporter superfamily
AL485_RS22670	COG4932	domain protein
AL485_RS22675	COG2197	response regulator
AL485_RS22680	COG3850	Histidine kinase
AL485_RS22685	COG2223	nitrite transmembrane transporter activity
AL485_RS22690	COG3710	Transcriptional regulator
AL485_RS22695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL485_RS22700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL485_RS22710	COG0489	protein tyrosine kinase activity
AL485_RS22710	COG3206	protein involved in exopolysaccharide biosynthesis
AL485_RS22730	COG0438	transferase activity, transferring glycosyl groups
AL485_RS22745	COG1216	Glycosyl transferase, family 2
AL485_RS22750	COG1216	Glycosyl transferase, family 2
AL485_RS22750	COG0463	Glycosyl transferase, family 2
AL485_RS22760	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL485_RS22765	COG1140	nitrate reductase beta subunit
AL485_RS22770	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL485_RS22775	COG2181	nitrate reductase activity
AL485_RS22780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL485_RS22785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL485_RS22835	COG1294	oxidase, subunit
AL485_RS22840	COG1271	oxidase subunit
AL485_RS22845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL485_RS22855	COG0601	transmembrane transport
AL485_RS22865	COG0444	Belongs to the ABC transporter superfamily
AL485_RS22870	COG4608	Belongs to the ABC transporter superfamily
AL485_RS22885	COG1609	Transcriptional regulator
AL485_RS22895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL485_RS22900	COG0395	ABC-type sugar transport system, permease component
AL485_RS22905	COG1175	transmembrane transport
AL485_RS22915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL485_RS22920	COG3138	arginine N-succinyltransferase
AL485_RS22925	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS22930	COG3724	N-succinylarginine dihydrolase activity
AL485_RS22935	COG2988	succinylglutamate desuccinylase activity
AL485_RS22955	COG1652	LysM domain
AL485_RS22970	COG2207	Transcriptional regulator
AL485_RS23015	COG1113	amino acid transport
AL485_RS23045	COG2226	methyltransferase
AL485_RS23050	COG1971	Probably functions as a manganese efflux pump
AL485_RS23055	COG4811	Protein of unknown function (DUF986)
AL485_RS23060	COG3716	PTS system mannose fructose sorbose family IID component
AL485_RS23065	COG3715	PTS system
AL485_RS23070	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS23070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL485_RS23075	COG1253	flavin adenine dinucleotide binding
AL485_RS23080	COG2200	EAL domain
AL485_RS23085	COG1760	l-serine dehydratase
AL485_RS23090	COG0494	nUDIX hydrolase
AL485_RS23100	COG1216	Glycosyl transferase, family 2
AL485_RS23105	COG3140	Belongs to the UPF0181 family
AL485_RS23110	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL485_RS23115	COG0513	Belongs to the DEAD box helicase family
AL485_RS23120	COG3141	response to X-ray
AL485_RS23125	COG3097	Belongs to the UPF0267 family
AL485_RS23145	COG2999	glutathione oxidoreductase activity
AL485_RS23155	COG0477	Major facilitator Superfamily
AL485_RS23160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL485_RS23165	COG3132	Protein of unknown function, DUF480
AL485_RS23180	COG0018	arginyl-trna synthetase
AL485_RS23185	COG3102	Protein conserved in bacteria
AL485_RS23190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL485_RS23195	COG3142	Participates in the control of copper homeostasis
AL485_RS23205	COG0500	methyltransferase
AL485_RS23210	COG2226	methyltransferase
AL485_RS23215	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AL485_RS23220	COG1801	Protein of unknown function DUF72
AL485_RS23225	COG1335	isochorismatase
AL485_RS23235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL485_RS23240	COG0494	nUDIX hydrolase
AL485_RS23245	COG0217	transcriptional regulatory protein
AL485_RS23250	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AL485_RS23255	COG0632	four-way junction helicase activity
AL485_RS23260	COG2255	four-way junction helicase activity
AL485_RS23265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL485_RS23270	COG1121	(ABC) transporter
AL485_RS23275	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL485_RS23280	COG0739	heme binding
AL485_RS23285	COG1560	Kdo2-lipid A biosynthetic process
AL485_RS23295	COG0469	pyruvate kinase activity
AL485_RS23300	COG1737	Transcriptional regulator
AL485_RS23305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL485_RS23310	COG0800	Aldolase
AL485_RS23315	COG2076	Multidrug Resistance protein
AL485_RS23320	COG2076	Multidrug Resistance protein
AL485_RS23325	COG0251	oxidation-reduction process
AL485_RS23330	COG1199	ATP-dependent helicase activity
AL485_RS23340	COG3065	identical protein binding
AL485_RS23345	COG0318	PFAM AMP-dependent synthetase and ligase
AL485_RS23350	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL485_RS23355	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL485_RS23360	COG2894	cell division
AL485_RS23365	COG0850	regulation of cytokinetic process
AL485_RS23370	COG3100	YcgL domain-containing protein
AL485_RS23375	COG2951	lytic endotransglycosylase activity
AL485_RS23380	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL485_RS23390	COG2983	Belongs to the UPF0260 family
AL485_RS23395	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL485_RS23400	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL485_RS23405	COG2186	Transcriptional regulator
AL485_RS23410	COG2719	SpoVR family
AL485_RS23415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL485_RS23420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL485_RS23450	COG0444	Belongs to the ABC transporter superfamily
AL485_RS23465	COG4774	siderophore transport
AL485_RS23475	COG0401	homolog of Blt101
AL485_RS23510	COG2718	Belongs to the UPF0229 family
AL485_RS23520	COG2766	serine protein kinase
AL485_RS23525	COG3713	MltA-interacting MipA family protein
AL485_RS23535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL485_RS23540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL485_RS23545	COG3139	Protein of unknown function (DUF1315)
AL485_RS23555	COG1335	isochorismatase
AL485_RS23560	COG0252	asparaginase activity
AL485_RS23565	COG0616	signal peptide processing
AL485_RS23570	COG0778	Nitroreductase
AL485_RS23580	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AL485_RS23585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL485_RS23595	COG0494	nUDIX hydrolase
AL485_RS23600	COG0708	Exodeoxyribonuclease III
AL485_RS23630	COG0788	formyltetrahydrofolate deformylase activity
AL485_RS23635	COG3012	SEC-C Motif Domain Protein
AL485_RS23640	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL485_RS23645	COG0745	RESPONSE REGULATOR receiver
AL485_RS23650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL485_RS23675	COG1012	belongs to the aldehyde dehydrogenase family
AL485_RS23675	COG1454	alcohol dehydrogenase
AL485_RS23680	COG2095	MarC family integral membrane protein
AL485_RS23685	COG4166	transmembrane transport
AL485_RS23700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL485_RS23705	COG0444	Belongs to the ABC transporter superfamily
AL485_RS23730	COG3192	ethanolamine utilization protein
AL485_RS23735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL485_RS23745	COG3099	Belongs to the UPF0263 family
AL485_RS23750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL485_RS23760	COG0783	Belongs to the Dps family
AL485_RS23785	COG0582	viral genome integration into host DNA
AL485_RS23910	COG3179	chitinase
AL485_RS23990	COG0741	lytic transglycosylase activity
AL485_RS24010	COG2350	Protein conserved in bacteria
AL485_RS24015	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL485_RS24035	COG1609	Transcriptional regulator
AL485_RS24040	COG1607	acyl-coa hydrolase
AL485_RS24045	COG2917	probably involved in intracellular septation
AL485_RS24060	COG0727	PFAM Uncharacterised protein family (UPF0153)
AL485_RS24065	COG3047	cAMP biosynthetic process
AL485_RS24075	COG0159	tryptophan synthase activity
AL485_RS24080	COG0133	tryptophan synthase activity
AL485_RS24090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL485_RS24105	COG0613	PHP domain protein
AL485_RS24110	COG0009	L-threonylcarbamoyladenylate synthase
AL485_RS24125	COG1187	pseudouridine synthase activity
AL485_RS24130	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL485_RS24135	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS24140	COG0616	signal peptide processing
AL485_RS24155	COG0583	DNA-binding transcription factor activity
AL485_RS24165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL485_RS24175	COG0671	phosphoesterase, PA-phosphatase related
AL485_RS24180	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL485_RS24185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL485_RS24205	COG0023	Translation Initiation Factor
AL485_RS24215	COG0235	Class ii aldolase
AL485_RS24220	COG1349	DNA-binding transcription factor activity
AL485_RS24225	COG1882	Formate acetyltransferase
AL485_RS24230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL485_RS24235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL485_RS24240	COG1966	Carbon starvation protein
AL485_RS24245	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL485_RS24260	COG0243	molybdopterin cofactor binding
AL485_RS24270	COG0583	DNA-binding transcription factor activity
AL485_RS24275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL485_RS24275	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL485_RS24295	COG4171	peptide transport system, permease
AL485_RS24310	COG1469	GTP cyclohydrolase I activity
AL485_RS24325	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL485_RS24330	COG1842	Phage shock protein A
AL485_RS24340	COG1983	PspC domain protein
AL485_RS24350	COG3106	COG3106 Predicted ATPase
AL485_RS24355	COG3768	UPF0283 membrane protein
AL485_RS24365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL485_RS24370	COG4948	Mandelate Racemase Muconate Lactonizing
AL485_RS24375	COG2866	Carboxypeptidase
AL485_RS24385	COG4166	transmembrane transport
AL485_RS24410	COG0037	tRNA processing
AL485_RS24425	COG0789	Transcriptional regulator
AL485_RS24450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL485_RS24455	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL485_RS24455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AL485_RS24455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL485_RS24455	COG0674	pyruvate-flavodoxin oxidoreductase activity
AL485_RS24465	COG3042	response to heat
AL485_RS24470	COG3187	Heat shock protein
AL485_RS24475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL485_RS24480	COG2911	Protein conserved in bacteria
AL485_RS24490	COG3784	Protein of unknown function (DUF1318)
AL485_RS24495	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL485_RS24500	COG1643	Atp-dependent helicase
AL485_RS24505	COG2814	Major facilitator Superfamily
AL485_RS24515	COG3591	Belongs to the peptidase S1B family
AL485_RS24525	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL485_RS24530	COG2205	protein histidine kinase activity
AL485_RS24535	COG0745	RESPONSE REGULATOR receiver
AL485_RS24540	COG1028	Short-chain dehydrogenase reductase Sdr
AL485_RS24550	COG0531	amino acid
AL485_RS24565	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL485_RS24570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL485_RS24575	COG0589	response to stress
AL485_RS24585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL485_RS24600	COG2222	sugar isomerase
AL485_RS24605	COG1349	DNA-binding transcription factor activity
AL485_RS24610	COG1940	carbohydrate kinase activity
AL485_RS24620	COG3842	ATPase activity
AL485_RS24625	COG0395	ABC-type sugar transport system, permease component
AL485_RS24630	COG1175	transmembrane transport
AL485_RS24655	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AL485_RS24680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL485_RS24695	COG0306	phosphate transporter
AL485_RS24755	COG3158	transport of potassium into the cell
AL485_RS24765	COG1309	transcriptional regulator
AL485_RS24795	COG0697	spore germination
AL485_RS24800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL485_RS24825	COG2239	Acts as a magnesium transporter
AL485_RS24845	COG0488	(ABC) transporter
AL485_RS24850	COG1511	domain protein
AL485_RS24850	COG3264	Mechanosensitive ion channel
AL485_RS24855	COG1054	Belongs to the UPF0176 family
AL485_RS24860	COG2190	(PTS) system
AL485_RS24860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL485_RS24860	COG1263	PTS System
AL485_RS24865	COG0583	DNA-binding transcription factor activity
AL485_RS24870	COG1653	transport
AL485_RS24890	COG3842	ATPase activity
AL485_RS24895	COG0366	Alpha amylase catalytic
AL485_RS24900	COG2199	diguanylate cyclase activity
AL485_RS24905	COG5507	3-demethylubiquinone-9 3-methyltransferase
AL485_RS24915	COG3048	D-serine ammonia-lyase activity
AL485_RS24940	COG2723	6-phospho-beta-galactosidase activity
AL485_RS24945	COG1737	Transcriptional regulator
AL485_RS24950	COG2271	Major facilitator Superfamily
AL485_RS24955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL485_RS24960	COG2080	2 iron, 2 sulfur cluster binding
AL485_RS24965	COG2010	Cytochrome c
AL485_RS24965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL485_RS24970	COG2010	Cytochrome c
AL485_RS24970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL485_RS24985	COG1396	sequence-specific DNA binding
AL485_RS25000	COG0583	DNA-binding transcription factor activity
AL485_RS25005	COG2957	Belongs to the agmatine deiminase family
AL485_RS25030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL485_RS25045	COG0693	protein deglycase activity
AL485_RS25050	COG0318	PFAM AMP-dependent synthetase and ligase
AL485_RS25055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL485_RS25060	COG1113	amino acid transport
AL485_RS25070	COG1846	Transcriptional regulator
AL485_RS25070	COG0456	acetyltransferase
AL485_RS25085	COG0583	DNA-binding transcription factor activity
AL485_RS25100	COG2272	Belongs to the type-B carboxylesterase lipase family
AL485_RS25105	COG0583	DNA-binding transcription factor activity
AL485_RS25110	COG2610	gluconate transmembrane transporter activity
AL485_RS25115	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL485_RS25115	COG1902	pentaerythritol trinitrate reductase activity
AL485_RS25120	COG0789	Transcriptional regulator
AL485_RS25150	COG2197	response regulator