locus-tag	class	description
AM681_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM681_RS00010	COG0592	DNA-directed DNA polymerase activity
AM681_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM681_RS00025	COG0187	DNA topoisomerase II activity
AM681_RS00030	COG0561	phosphatase activity
AM681_RS00035	COG2423	ornithine cyclodeaminase activity
AM681_RS00040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM681_RS00050	COG0823	Involved in the tonB-independent uptake of proteins
AM681_RS00055	COG5645	(Lipo)protein
AM681_RS00060	COG0071	Belongs to the small heat shock protein (HSP20) family
AM681_RS00080	COG0071	Belongs to the small heat shock protein (HSP20) family
AM681_RS00085	COG2985	domain, Protein
AM681_RS00095	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM681_RS00100	COG3977	Valine--pyruvate aminotransferase
AM681_RS00105	COG0366	Alpha amylase catalytic
AM681_RS00110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM681_RS00115	COG2814	Major facilitator Superfamily
AM681_RS00120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM681_RS00130	COG1609	Transcriptional regulator
AM681_RS00135	COG2885	chlorophyll binding
AM681_RS00145	COG2818	Glycosylase
AM681_RS00155	COG0752	glycyl-tRNA synthetase alpha subunit
AM681_RS00160	COG0751	glycine-tRNA ligase activity
AM681_RS00170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS00170	COG2213	PTS system mannitol-specific
AM681_RS00175	COG0246	Mannitol dehydrogenase
AM681_RS00180	COG3722	fumarate hydratase activity
AM681_RS00190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM681_RS00205	COG2258	MOSC domain
AM681_RS00215	COG0840	transmembrane signaling receptor activity
AM681_RS00220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM681_RS00225	COG0243	molybdopterin cofactor binding
AM681_RS00225	COG3383	formate dehydrogenase (NAD+) activity
AM681_RS00230	COG3383	formate dehydrogenase (NAD+) activity
AM681_RS00230	COG0243	molybdopterin cofactor binding
AM681_RS00235	COG0437	4 iron, 4 sulfur cluster binding
AM681_RS00240	COG2864	formate dehydrogenase
AM681_RS00245	COG3058	Necessary for formate dehydrogenase activity
AM681_RS00255	COG0625	glutathione transferase activity
AM681_RS00260	COG1921	L-seryl-tRNASec selenium transferase activity
AM681_RS00265	COG3276	selenocysteine insertion sequence binding
AM681_RS00270	COG0583	DNA-binding transcription factor activity
AM681_RS00285	COG3274	enterobacterial common antigen metabolic process
AM681_RS00295	COG1335	isochorismatase
AM681_RS00300	COG0402	S-adenosylhomocysteine deaminase activity
AM681_RS00315	COG0583	DNA-binding transcription factor activity
AM681_RS00320	COG2807	transmembrane transport
AM681_RS00345	COG2814	Major facilitator Superfamily
AM681_RS00380	COG1846	Transcriptional regulator
AM681_RS00385	COG1764	response to oxidative stress
AM681_RS00390	COG2194	sulfuric ester hydrolase activity
AM681_RS00395	COG2197	response regulator
AM681_RS00405	COG2271	Major facilitator Superfamily
AM681_RS00430	COG0747	negative chemotaxis
AM681_RS00435	COG0601	transmembrane transport
AM681_RS00440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM681_RS00445	COG0444	Belongs to the ABC transporter superfamily
AM681_RS00450	COG4608	Belongs to the ABC transporter superfamily
AM681_RS00455	COG2194	sulfuric ester hydrolase activity
AM681_RS00485	COG1215	transferase activity, transferring glycosyl groups
AM681_RS00490	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM681_RS00495	COG0457	Tetratricopeptide repeat
AM681_RS00495	COG3118	belongs to the thioredoxin family
AM681_RS00500	COG2200	EAL domain
AM681_RS00500	COG2199	diguanylate cyclase activity
AM681_RS00505	COG1301	dicarboxylic acid transport
AM681_RS00510	COG0612	Peptidase, M16
AM681_RS00515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM681_RS00525	COG0248	Ppx GppA phosphatase
AM681_RS00535	COG3118	belongs to the thioredoxin family
AM681_RS00540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM681_RS00545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM681_RS00555	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM681_RS00560	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM681_RS00565	COG1088	dTDP-glucose 4,6-dehydratase activity
AM681_RS00570	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM681_RS00580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM681_RS00585	COG2244	polysaccharide biosynthetic process
AM681_RS00590	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM681_RS00600	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM681_RS00635	COG3071	HemY protein
AM681_RS00640	COG2959	enzyme of heme biosynthesis
AM681_RS00650	COG0181	hydroxymethylbilane synthase activity
AM681_RS00655	COG3072	Adenylate cyclase
AM681_RS00660	COG1965	Belongs to the frataxin family
AM681_RS00665	COG5567	small periplasmic lipoprotein
AM681_RS00670	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM681_RS00675	COG3159	Protein conserved in bacteria
AM681_RS00685	COG1011	Hydrolase
AM681_RS00690	COG0210	DNA helicase
AM681_RS00710	COG2050	protein possibly involved in aromatic compounds catabolism
AM681_RS00720	COG0514	ATP-dependent DNA helicase (RecQ)
AM681_RS00725	COG1280	lysine exporter protein (LysE YggA)
AM681_RS00730	COG1280	lysine exporter protein (LysE YggA)
AM681_RS00735	COG2267	carboxylic ester hydrolase activity
AM681_RS00740	COG0561	phosphatase activity
AM681_RS00750	COG0584	glycerophosphoryl diester phosphodiesterase
AM681_RS00755	COG2271	Major facilitator Superfamily
AM681_RS00765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM681_RS00775	COG0247	lactate metabolic process
AM681_RS00790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM681_RS00795	COG0425	Belongs to the sulfur carrier protein TusA family
AM681_RS00810	COG2217	Heavy metal translocating P-type atpase
AM681_RS00825	COG3714	YhhN family
AM681_RS00835	COG3776	membrane
AM681_RS00840	COG0742	ribosomal rna small subunit methyltransferase
AM681_RS00845	COG0552	protein localization to endoplasmic reticulum
AM681_RS00845	COG0552	protein localization to endoplasmic reticulum
AM681_RS00850	COG2884	Cell division ATP-binding protein ftsE
AM681_RS00855	COG2177	Part of the ABC transporter FtsEX involved in
AM681_RS00880	COG0456	acetyltransferase
AM681_RS00890	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM681_RS00895	COG4177	L-phenylalanine transmembrane transporter activity
AM681_RS00905	COG0410	ABC transporter
AM681_RS00910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM681_RS00915	COG1653	transport
AM681_RS00920	COG1175	transmembrane transport
AM681_RS00930	COG3842	ATPase activity
AM681_RS00935	COG0584	glycerophosphoryl diester phosphodiesterase
AM681_RS00950	COG0697	spore germination
AM681_RS00960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM681_RS00965	COG0412	Dienelactone hydrolase
AM681_RS00985	COG0586	Pfam SNARE associated Golgi protein
AM681_RS00990	COG1322	Protein conserved in bacteria
AM681_RS00995	COG2226	methyltransferase
AM681_RS01000	COG3165	ubiquinone biosynthetic process from chorismate
AM681_RS01005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM681_RS01010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM681_RS01020	COG0805	protein transport
AM681_RS01025	COG0084	hydrolase, TatD family'
AM681_RS01055	COG0183	Belongs to the thiolase family
AM681_RS01060	COG1024	Enoyl-CoA hydratase
AM681_RS01060	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM681_RS01070	COG0006	proline dipeptidase activity
AM681_RS01075	COG1739	Uncharacterized protein family UPF0029
AM681_RS01080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM681_RS01110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM681_RS01115	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM681_RS01115	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM681_RS01120	COG1072	(Pantothenic acid kinase))
AM681_RS01155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM681_RS01165	COG0250	Participates in transcription elongation, termination and antitermination
AM681_RS01180	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM681_RS01190	COG0085	RNA polymerase activity
AM681_RS01195	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM681_RS01210	COG5002	protein histidine kinase activity
AM681_RS01225	COG2022	thiamine diphosphate biosynthetic process
AM681_RS01230	COG2104	thiamine diphosphate biosynthetic process
AM681_RS01235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM681_RS01240	COG0352	thiamine-phosphate diphosphorylase activity
AM681_RS01245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AM681_RS01250	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AM681_RS01255	COG2816	NAD+ diphosphatase activity
AM681_RS01260	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM681_RS01265	COG1515	deoxyribonuclease V activity
AM681_RS01285	COG0151	Belongs to the GarS family
AM681_RS01290	COG0138	bifunctional purine biosynthesis protein purh
AM681_RS01320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM681_RS01325	COG3162	membrane
AM681_RS01330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM681_RS01335	COG1301	dicarboxylic acid transport
AM681_RS01340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM681_RS01340	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM681_RS01345	COG3433	isochorismatase activity
AM681_RS01345	COG2226	methyltransferase
AM681_RS01345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM681_RS01350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM681_RS01355	COG4774	siderophore transport
AM681_RS01355	COG1629	transport
AM681_RS01360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM681_RS01365	COG3391	amine dehydrogenase activity
AM681_RS01370	COG4771	TonB-dependent receptor
AM681_RS01375	COG2382	esterase
AM681_RS01385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM681_RS01385	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM681_RS01395	COG1169	isochorismate synthase
AM681_RS01400	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM681_RS01405	COG1535	isochorismatase
AM681_RS01405	COG3433	isochorismatase activity
AM681_RS01415	COG3647	Membrane
AM681_RS01430	COG1309	transcriptional regulator
AM681_RS01435	COG4232	protein-disulfide reductase activity
AM681_RS01445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM681_RS01465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM681_RS01485	COG1509	lysine 2,3-aminomutase activity
AM681_RS01490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM681_RS01495	COG5510	response to toxic substance
AM681_RS01500	COG5510	response to toxic substance
AM681_RS01510	COG3040	lipid binding
AM681_RS01515	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM681_RS01520	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM681_RS01525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM681_RS01530	COG1053	succinate dehydrogenase
AM681_RS01535	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM681_RS01540	COG1511	domain protein
AM681_RS01540	COG3264	Mechanosensitive ion channel
AM681_RS01545	COG0688	phosphatidylethanolamine metabolic process
AM681_RS01550	COG1162	GTPase activity
AM681_RS01555	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM681_RS01575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM681_RS01580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM681_RS01580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM681_RS01585	COG0802	atpase or kinase
AM681_RS01595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM681_RS01600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM681_RS01610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM681_RS01615	COG0330	HflC and HflK could
AM681_RS01620	COG0330	HflC and HflK could
AM681_RS01625	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM681_RS01630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM681_RS01635	COG1959	2 iron, 2 sulfur cluster binding
AM681_RS01640	COG0557	exoribonuclease II activity
AM681_RS01645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM681_RS01650	COG1960	acyl-CoA dehydrogenase activity
AM681_RS01655	COG3766	membrane
AM681_RS01665	COG3650	response to hydrogen peroxide
AM681_RS01670	COG1073	alpha beta
AM681_RS01685	COG0360	Binds together with S18 to 16S ribosomal RNA
AM681_RS01695	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM681_RS01700	COG0359	binds to the 23S rRNA
AM681_RS01710	COG3061	Opacity-associated protein A
AM681_RS01715	COG0545	Peptidyl-prolyl cis-trans isomerase
AM681_RS01730	COG0737	Belongs to the 5'-nucleotidase family
AM681_RS01740	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM681_RS01750	COG1253	flavin adenine dinucleotide binding
AM681_RS01755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM681_RS01760	COG0729	surface antigen
AM681_RS01765	COG2911	Protein conserved in bacteria
AM681_RS01770	COG2105	PFAM AIG2 family protein
AM681_RS01775	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM681_RS01785	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM681_RS01790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM681_RS01805	COG1438	arginine binding
AM681_RS01810	COG0039	L-malate dehydrogenase activity
AM681_RS01815	COG3423	Transcriptional regulator
AM681_RS01825	COG0142	geranyltranstransferase activity
AM681_RS01830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM681_RS01835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM681_RS01840	COG0697	spore germination
AM681_RS01845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM681_RS01850	COG0642	Histidine kinase
AM681_RS01855	COG0745	RESPONSE REGULATOR receiver
AM681_RS01860	COG2027	D-alanyl-D-alanine carboxypeptidase
AM681_RS01870	COG1534	Rna-binding protein
AM681_RS01875	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AM681_RS01885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM681_RS01890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM681_RS01895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM681_RS01910	COG0779	Required for maturation of 30S ribosomal subunits
AM681_RS01915	COG0195	Participates in both transcription termination and antitermination
AM681_RS01920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM681_RS01925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM681_RS01930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM681_RS01935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM681_RS01945	COG1185	polyribonucleotide nucleotidyltransferase activity
AM681_RS01960	COG0513	Belongs to the DEAD box helicase family
AM681_RS01965	COG2391	methyltransferase activity
AM681_RS01970	COG0425	Belongs to the sulfur carrier protein TusA family
AM681_RS01975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM681_RS02005	COG0826	peptidase U32
AM681_RS02010	COG0826	peptidase U32
AM681_RS02015	COG3154	lipid carrier protein
AM681_RS02020	COG3153	acetyltransferase
AM681_RS02025	COG2827	Endonuclease containing a URI domain
AM681_RS02030	COG0531	amino acid
AM681_RS02035	COG1982	Orn Lys Arg decarboxylase major
AM681_RS02045	COG3787	Belongs to the UPF0306 family
AM681_RS02050	COG0702	epimerase
AM681_RS02055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM681_RS02065	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM681_RS02070	COG3454	Phosphonate metabolism
AM681_RS02075	COG4778	phosphonate C-P lyase system protein PhnL
AM681_RS02080	COG4107	phosphonate C-P lyase system protein PhnK
AM681_RS02085	COG3627	carbon phosphorus lyase activity
AM681_RS02090	COG3626	phosphonate metabolism
AM681_RS02095	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM681_RS02100	COG3624	Phosphonate C-P lyase system protein PhnG
AM681_RS02105	COG2188	Transcriptional regulator
AM681_RS02110	COG0701	Predicted permease
AM681_RS02125	COG0602	queuosine metabolic process
AM681_RS02140	COG0583	DNA-binding transcription factor activity
AM681_RS02145	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM681_RS02150	COG0366	Alpha amylase catalytic
AM681_RS02155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM681_RS02155	COG1263	PTS System
AM681_RS02165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM681_RS02170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AM681_RS02185	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AM681_RS02190	COG0540	Belongs to the ATCase OTCase family
AM681_RS02200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM681_RS02215	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM681_RS02220	COG0456	acetyltransferase
AM681_RS02230	COG2927	DNA polymerase III (CHI subunit)
AM681_RS02235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM681_RS02240	COG0795	lipopolysaccharide-transporting ATPase activity
AM681_RS02245	COG0795	lipopolysaccharide-transporting ATPase activity
AM681_RS02255	COG2610	gluconate transmembrane transporter activity
AM681_RS02260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM681_RS02265	COG1349	DNA-binding transcription factor activity
AM681_RS02300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM681_RS02325	COG3727	T/G mismatch-specific endonuclease activity
AM681_RS02365	COG0523	cobalamin synthesis protein
AM681_RS02370	COG2879	small protein
AM681_RS02375	COG1966	Carbon starvation protein
AM681_RS02400	COG1116	anion transmembrane transporter activity
AM681_RS02410	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM681_RS02420	COG0174	glutamine synthetase
AM681_RS02450	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AM681_RS02460	COG0583	DNA-binding transcription factor activity
AM681_RS02465	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM681_RS02485	COG2610	gluconate transmembrane transporter activity
AM681_RS02490	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS02500	COG2207	Transcriptional regulator
AM681_RS02515	COG1376	ErfK ybiS ycfS ynhG family protein
AM681_RS02550	COG0811	peptide transport
AM681_RS02570	COG1473	amidohydrolase
AM681_RS02595	COG1454	alcohol dehydrogenase
AM681_RS02605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM681_RS02615	COG2267	carboxylic ester hydrolase activity
AM681_RS02650	COG1113	amino acid transport
AM681_RS02670	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS02675	COG1846	Transcriptional regulator
AM681_RS02680	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM681_RS02690	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS02695	COG3384	dioxygenase
AM681_RS02705	COG3971	2-oxopent-4-enoate hydratase activity
AM681_RS02725	COG2368	4-hydroxyphenylacetate
AM681_RS02730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM681_RS02735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM681_RS02740	COG2186	Transcriptional regulator
AM681_RS02745	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS02755	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM681_RS02760	COG4948	Mandelate Racemase Muconate Lactonizing
AM681_RS02765	COG3618	amidohydrolase
AM681_RS02775	COG3254	rhamnose metabolic process
AM681_RS02780	COG0738	Major facilitator superfamily
AM681_RS02805	COG3706	GGDEF domain
AM681_RS02830	COG0583	DNA-binding transcription factor activity
AM681_RS02835	COG0667	Aldo Keto reductase
AM681_RS02840	COG2813	Specifically methylates the guanine in position
AM681_RS02845	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM681_RS02855	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM681_RS02860	COG2823	Periplasmic or secreted lipoprotein
AM681_RS02865	COG5487	UPF0391 membrane protein
AM681_RS02870	COG3237	CsbD-like
AM681_RS02875	COG4667	esterase of the alpha-beta hydrolase superfamily
AM681_RS02880	COG0084	hydrolase, TatD family'
AM681_RS02885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM681_RS02890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM681_RS02900	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM681_RS02905	COG0813	purine-nucleoside phosphorylase activity
AM681_RS02910	COG3550	peptidyl-serine autophosphorylation
AM681_RS02915	COG3726	membrane protein affecting hemolysin expression
AM681_RS02920	COG0560	Phosphoserine phosphatase
AM681_RS02940	COG0604	alcohol dehydrogenase
AM681_RS02950	COG0488	(ABC) transporter
AM681_RS02955	COG2885	chlorophyll binding
AM681_RS02960	COG2199	diguanylate cyclase activity
AM681_RS02970	COG0741	lytic transglycosylase activity
AM681_RS02975	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AM681_RS02980	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AM681_RS02985	COG0406	alpha-ribazole phosphatase activity
AM681_RS02990	COG3708	Transcriptional regulator
AM681_RS02990	COG2207	Transcriptional regulator
AM681_RS02995	COG3045	CreA protein
AM681_RS03000	COG0745	RESPONSE REGULATOR receiver
AM681_RS03030	COG3022	response to hydroperoxide
AM681_RS03035	COG1115	amino acid carrier protein
AM681_RS03040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM681_RS03045	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM681_RS03060	COG1584	GPR1 FUN34 yaaH family protein
AM681_RS03065	COG0443	Heat shock 70 kDa protein
AM681_RS03070	COG0484	heat shock protein binding
AM681_RS03075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM681_RS03080	COG0583	DNA-binding transcription factor activity
AM681_RS03085	COG0268	Binds directly to 16S ribosomal RNA
AM681_RS03095	COG0196	riboflavin kinase activity
AM681_RS03100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM681_RS03105	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM681_RS03110	COG1047	Peptidyl-prolyl cis-trans
AM681_RS03115	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AM681_RS03120	COG0583	DNA-binding transcription factor activity
AM681_RS03140	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM681_RS03145	COG0505	Belongs to the CarA family
AM681_RS03150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM681_RS03170	COG2966	Psort location CytoplasmicMembrane, score
AM681_RS03180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM681_RS03190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM681_RS03195	COG2967	ApaG domain
AM681_RS03200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM681_RS03205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM681_RS03215	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM681_RS03225	COG0564	pseudouridine synthase activity
AM681_RS03230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM681_RS03235	COG0417	DNA replication proofreading
AM681_RS03240	COG0586	Pfam SNARE associated Golgi protein
AM681_RS03245	COG0440	acetolactate synthase activity
AM681_RS03250	COG0028	Belongs to the TPP enzyme family
AM681_RS03265	COG1178	ABC-type Fe3 transport system permease component
AM681_RS03270	COG4143	(ABC) transporter
AM681_RS03285	COG2814	Major facilitator Superfamily
AM681_RS03290	COG0471	metal ion transport
AM681_RS03295	COG0066	3-isopropylmalate dehydratase activity
AM681_RS03300	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM681_RS03305	COG0473	3-isopropylmalate dehydrogenase activity
AM681_RS03310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM681_RS03325	COG1022	Amp-dependent synthetase and ligase
AM681_RS03330	COG0028	Belongs to the TPP enzyme family
AM681_RS03350	COG2001	Belongs to the MraZ family
AM681_RS03355	COG0275	rRNA processing
AM681_RS03360	COG3116	cell division
AM681_RS03365	COG0768	penicillin binding
AM681_RS03370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM681_RS03375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM681_RS03380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM681_RS03390	COG0772	Belongs to the SEDS family
AM681_RS03395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM681_RS03400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM681_RS03410	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM681_RS03415	COG0849	cell division
AM681_RS03420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM681_RS03440	COG0653	protein targeting
AM681_RS03445	COG0494	nUDIX hydrolase
AM681_RS03450	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM681_RS03455	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AM681_RS03465	COG0516	GMP reductase activity
AM681_RS03470	COG1459	type II secretion system
AM681_RS03475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM681_RS03480	COG4969	Belongs to the N-Me-Phe pilin family
AM681_RS03490	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM681_RS03495	COG3725	Membrane protein required for beta-lactamase induction
AM681_RS03500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM681_RS03510	COG0316	Belongs to the HesB IscA family
AM681_RS03520	COG2860	membrane
AM681_RS03530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM681_RS03535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AM681_RS03540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM681_RS03550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM681_RS03555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM681_RS03560	COG3956	TIGRFAM MazG family protein
AM681_RS03570	COG0504	CTP synthase activity
AM681_RS03580	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AM681_RS03595	COG2986	histidine ammonia-lyase
AM681_RS03605	COG2271	Major facilitator Superfamily
AM681_RS03610	COG0602	queuosine metabolic process
AM681_RS03615	COG0720	synthase
AM681_RS03620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM681_RS03625	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM681_RS03630	COG0175	sulfate reduction
AM681_RS03635	COG2234	aminopeptidase activity
AM681_RS03640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM681_RS03640	COG1648	precorrin-2 dehydrogenase activity
AM681_RS03645	COG0175	sulfate reduction
AM681_RS03650	COG2895	sulfate adenylyltransferase (ATP) activity
AM681_RS03670	COG0765	amino acid transport
AM681_RS03680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AM681_RS03685	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM681_RS03690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM681_RS03695	COG0585	pseudouridine synthase activity
AM681_RS03700	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM681_RS03705	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM681_RS03710	COG4942	peptidase
AM681_RS03710	COG1388	LysM domain
AM681_RS03715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM681_RS03720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM681_RS03725	COG0582	viral genome integration into host DNA
AM681_RS03795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AM681_RS03805	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM681_RS03845	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM681_RS03850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM681_RS03855	COG2723	6-phospho-beta-galactosidase activity
AM681_RS03860	COG2169	Transcriptional regulator
AM681_RS03860	COG1917	Cupin 2, conserved barrel domain protein
AM681_RS03885	COG2137	regulation of response to DNA damage stimulus
AM681_RS03890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM681_RS03895	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM681_RS03925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM681_RS03930	COG1238	metal cluster binding
AM681_RS03935	COG2918	glutathione biosynthetic process
AM681_RS03950	COG4536	flavin adenine dinucleotide binding
AM681_RS03955	COG4137	Cytochrome C assembly protein
AM681_RS03960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM681_RS03965	COG0228	four-way junction DNA binding
AM681_RS03970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM681_RS03980	COG0335	large ribosomal subunit rRNA binding
AM681_RS04000	COG3137	Salt-induced outer membrane protein
AM681_RS04005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM681_RS04010	COG0287	Prephenate dehydrogenase
AM681_RS04010	COG1605	Chorismate mutase
AM681_RS04015	COG0077	Prephenate dehydratase
AM681_RS04015	COG1605	Chorismate mutase
AM681_RS04025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM681_RS04030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM681_RS04040	COG0564	pseudouridine synthase activity
AM681_RS04050	COG0542	response to heat
AM681_RS04080	COG0656	L-ascorbic acid biosynthetic process
AM681_RS04085	COG0583	DNA-binding transcription factor activity
AM681_RS04095	COG0741	lytic transglycosylase activity
AM681_RS04095	COG1388	LysM domain
AM681_RS04100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM681_RS04105	COG2226	methyltransferase
AM681_RS04110	COG0328	RNA-DNA hybrid ribonuclease activity
AM681_RS04115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM681_RS04140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM681_RS04155	COG0436	Aminotransferase
AM681_RS04160	COG0235	Class ii aldolase
AM681_RS04165	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AM681_RS04170	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AM681_RS04175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AM681_RS04180	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AM681_RS04195	COG1960	acyl-CoA dehydrogenase activity
AM681_RS04200	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM681_RS04205	COG0121	glutamine amidotransferase
AM681_RS04210	COG3034	peptidoglycan biosynthetic process
AM681_RS04215	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM681_RS04220	COG1805	sodium ion transport
AM681_RS04225	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM681_RS04230	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM681_RS04235	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM681_RS04240	COG2871	sodium ion transport
AM681_RS04245	COG1477	protein flavinylation
AM681_RS04250	COG2991	Protein conserved in bacteria
AM681_RS04265	COG0584	glycerophosphoryl diester phosphodiesterase
AM681_RS04270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM681_RS04275	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM681_RS04280	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AM681_RS04285	COG1073	alpha beta
AM681_RS04310	COG2378	regulation of single-species biofilm formation
AM681_RS04325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM681_RS04330	COG0698	ribose 5-phosphate isomerase
AM681_RS04335	COG0149	triose-phosphate isomerase activity
AM681_RS04340	COG2390	Transcriptional regulator
AM681_RS04375	COG1129	ABC transporter
AM681_RS04380	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM681_RS04390	COG1349	DNA-binding transcription factor activity
AM681_RS04410	COG2003	Belongs to the UPF0758 family
AM681_RS04455	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM681_RS04465	COG2378	regulation of single-species biofilm formation
AM681_RS04475	COG2378	regulation of single-species biofilm formation
AM681_RS04485	COG3596	GTP binding
AM681_RS04515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM681_RS04540	COG0582	viral genome integration into host DNA
AM681_RS04550	COG2207	Transcriptional regulator
AM681_RS04565	COG3039	Transposase
AM681_RS04585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS04600	COG3009	Protein conserved in bacteria
AM681_RS04605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM681_RS04605	COG3008	intermembrane lipid transfer
AM681_RS04610	COG2995	paraquat-inducible protein a
AM681_RS04615	COG2990	Protein conserved in bacteria
AM681_RS04620	COG2819	hydrolase of the alpha beta superfamily
AM681_RS04625	COG2314	TM2 domain
AM681_RS04640	COG1335	isochorismatase
AM681_RS04665	COG3038	cytochrome b561
AM681_RS04670	COG0747	negative chemotaxis
AM681_RS04675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM681_RS04680	COG1733	regulation of RNA biosynthetic process
AM681_RS04685	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM681_RS04700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM681_RS04710	COG2207	Transcriptional regulator
AM681_RS04715	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS04725	COG2169	Transcriptional regulator
AM681_RS04725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM681_RS04745	COG3961	Belongs to the TPP enzyme family
AM681_RS04780	COG1349	DNA-binding transcription factor activity
AM681_RS04785	COG0346	lactoylglutathione lyase activity
AM681_RS04800	COG1335	isochorismatase
AM681_RS04810	COG3011	Protein conserved in bacteria
AM681_RS04820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM681_RS04825	COG3416	Protein conserved in bacteria
AM681_RS04835	COG2226	methyltransferase
AM681_RS04890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM681_RS04910	COG3123	guanosine phosphorylase activity
AM681_RS04915	COG2974	May be involved in recombination
AM681_RS04920	COG1940	carbohydrate kinase activity
AM681_RS04940	COG0419	ATPase involved in DNA repair
AM681_RS04945	COG0420	3'-5' exonuclease activity
AM681_RS04950	COG0745	RESPONSE REGULATOR receiver
AM681_RS04955	COG5002	protein histidine kinase activity
AM681_RS04980	COG0668	transmembrane transport
AM681_RS04985	COG0366	Alpha amylase catalytic
AM681_RS04995	COG0450	alkyl hydroperoxide reductase
AM681_RS05000	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AM681_RS05005	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM681_RS05010	COG0343	queuine tRNA-ribosyltransferase activity
AM681_RS05015	COG1862	Preprotein translocase
AM681_RS05025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM681_RS05030	COG4238	major outer membrane lipoprotein
AM681_RS05035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM681_RS05040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM681_RS05040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM681_RS05045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM681_RS05050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM681_RS05055	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM681_RS05060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM681_RS05065	COG0667	Aldo Keto reductase
AM681_RS05070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM681_RS05075	COG0142	geranyltranstransferase activity
AM681_RS05080	COG1722	exodeoxyribonuclease VII activity
AM681_RS05085	COG0301	tRNA thio-modification
AM681_RS05085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM681_RS05090	COG3210	domain, Protein
AM681_RS05095	COG2831	hemolysin activation secretion protein
AM681_RS05100	COG0693	protein deglycase activity
AM681_RS05105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM681_RS05110	COG1666	GTP binding
AM681_RS05115	COG2814	Major facilitator Superfamily
AM681_RS05120	COG0109	protoheme IX farnesyltransferase activity
AM681_RS05125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM681_RS05130	COG1845	cytochrome c oxidase, subunit III
AM681_RS05135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM681_RS05140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM681_RS05145	COG2223	nitrite transmembrane transporter activity
AM681_RS05150	COG3056	Lipoprotein
AM681_RS05155	COG0271	Belongs to the BolA IbaG family
AM681_RS05160	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM681_RS05170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM681_RS05175	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM681_RS05185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM681_RS05190	COG1555	photosystem II stabilization
AM681_RS05195	COG0824	Thioesterase
AM681_RS05200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM681_RS05205	COG4533	DNA binding
AM681_RS05210	COG0561	phosphatase activity
AM681_RS05220	COG1522	sequence-specific DNA binding
AM681_RS05225	COG1132	(ABC) transporter
AM681_RS05230	COG1132	(ABC) transporter
AM681_RS05235	COG0347	Belongs to the P(II) protein family
AM681_RS05240	COG0004	ammonium transporteR
AM681_RS05245	COG1946	Acyl-CoA thioesterase
AM681_RS05250	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM681_RS05255	COG3695	enzyme binding
AM681_RS05265	COG0582	viral genome integration into host DNA
AM681_RS05315	COG1121	(ABC) transporter
AM681_RS05320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM681_RS05325	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM681_RS05335	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM681_RS05340	COG0254	rRNA binding
AM681_RS05345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM681_RS05350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS05355	COG1309	transcriptional regulator
AM681_RS05360	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM681_RS05380	COG2832	Protein of unknown function (DUF454)
AM681_RS05385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM681_RS05390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM681_RS05400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM681_RS05405	COG0326	Molecular chaperone. Has ATPase activity
AM681_RS05415	COG0563	adenylate kinase activity
AM681_RS05420	COG3835	regulator
AM681_RS05425	COG2610	gluconate transmembrane transporter activity
AM681_RS05430	COG1929	Belongs to the glycerate kinase type-1 family
AM681_RS05435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM681_RS05440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM681_RS05450	COG4651	solute:proton antiporter activity
AM681_RS05450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM681_RS05455	COG2223	nitrite transmembrane transporter activity
AM681_RS05460	COG0737	Belongs to the 5'-nucleotidase family
AM681_RS05465	COG2027	D-alanyl-D-alanine carboxypeptidase
AM681_RS05470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM681_RS05475	COG3735	TraB family
AM681_RS05480	COG2217	Heavy metal translocating P-type atpase
AM681_RS05485	COG0789	Transcriptional regulator
AM681_RS05490	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM681_RS05495	COG0330	HflC and HflK could
AM681_RS05500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM681_RS05505	COG3118	belongs to the thioredoxin family
AM681_RS05510	COG0300	oxidoreductase activity
AM681_RS05515	COG2755	lipolytic protein G-D-S-L family
AM681_RS05520	COG4181	ATPase activity
AM681_RS05525	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM681_RS05530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM681_RS05535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM681_RS05540	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM681_RS05545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM681_RS05550	COG0215	cysteine-tRNA ligase activity
AM681_RS05555	COG2501	S4 domain
AM681_RS05560	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM681_RS05580	COG0582	viral genome integration into host DNA
AM681_RS05620	COG0577	efflux transmembrane transporter activity
AM681_RS05620	COG1136	(ABC) transporter
AM681_RS05660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM681_RS05665	COG2205	protein histidine kinase activity
AM681_RS05680	COG1368	sulfuric ester hydrolase activity
AM681_RS05695	COG2267	carboxylic ester hydrolase activity
AM681_RS05700	COG2072	flavoprotein involved in K transport
AM681_RS05730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM681_RS05750	COG2244	polysaccharide biosynthetic process
AM681_RS05755	COG1442	glycosyl transferase family 8
AM681_RS05755	COG1216	Glycosyl transferase, family 2
AM681_RS05770	COG2199	diguanylate cyclase activity
AM681_RS05775	COG1278	Cold shock
AM681_RS05785	COG1126	abc transporter atp-binding protein
AM681_RS05790	COG0765	amino acid transport
AM681_RS05800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM681_RS05805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM681_RS05810	COG1473	amidohydrolase
AM681_RS05820	COG2814	Major facilitator Superfamily
AM681_RS05825	COG1309	transcriptional regulator
AM681_RS05830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM681_RS05840	COG3706	GGDEF domain
AM681_RS05850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM681_RS05855	COG0321	lipoyl(octanoyl) transferase activity
AM681_RS05865	COG1686	Belongs to the peptidase S11 family
AM681_RS05870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM681_RS05875	COG0772	Belongs to the SEDS family
AM681_RS05880	COG0768	penicillin binding
AM681_RS05885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AM681_RS05890	COG0799	negative regulation of ribosome biogenesis
AM681_RS05895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM681_RS05900	COG1466	dna polymerase III delta subunit
AM681_RS05905	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AM681_RS05910	COG0495	leucyl-tRNA aminoacylation
AM681_RS05915	COG2888	peptidyl-tyrosine sulfation
AM681_RS05925	COG1957	nucleoside hydrolase
AM681_RS05930	COG1126	abc transporter atp-binding protein
AM681_RS05935	COG0765	amino acid transport
AM681_RS05940	COG0765	amino acid transport
AM681_RS05950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM681_RS05955	COG4535	Mg2 and Co2 transporter CorC
AM681_RS05960	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM681_RS05965	COG1702	phosphate starvation-inducible protein PhoH
AM681_RS05970	COG2824	Alkylphosphonate utilization operon protein PhnA
AM681_RS05975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM681_RS05980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM681_RS06020	COG0367	asparagine synthase
AM681_RS06025	COG3469	chitinase activity
AM681_RS06030	COG0647	UMP catabolic process
AM681_RS06035	COG1940	carbohydrate kinase activity
AM681_RS06035	COG1846	Transcriptional regulator
AM681_RS06040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM681_RS06045	COG0363	glucosamine-6-phosphate deaminase activity
AM681_RS06050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM681_RS06050	COG2190	(PTS) system
AM681_RS06050	COG1263	PTS System
AM681_RS06060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM681_RS06080	COG0735	belongs to the Fur family
AM681_RS06095	COG0596	Alpha beta hydrolase
AM681_RS06100	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AM681_RS06105	COG0033	Phosphoglucomutase
AM681_RS06110	COG1695	Transcriptional regulator
AM681_RS06120	COG0745	RESPONSE REGULATOR receiver
AM681_RS06125	COG2205	protein histidine kinase activity
AM681_RS06130	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AM681_RS06135	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM681_RS06140	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM681_RS06155	COG3272	Protein of unknown function (DUF1722)
AM681_RS06165	COG5212	phosphodiesterase
AM681_RS06170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM681_RS06175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM681_RS06180	COG1984	allophanate hydrolase subunit 2
AM681_RS06185	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AM681_RS06220	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM681_RS06225	COG1053	succinate dehydrogenase
AM681_RS06230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM681_RS06235	COG0567	Dehydrogenase, E1 component
AM681_RS06240	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM681_RS06245	COG0045	succinate-CoA ligase (ADP-forming) activity
AM681_RS06250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM681_RS06255	COG0737	Belongs to the 5'-nucleotidase family
AM681_RS06260	COG1271	oxidase subunit
AM681_RS06265	COG1294	oxidase, subunit
AM681_RS06270	COG4890	Cyd operon protein YbgT
AM681_RS06275	COG3790	cyd operon protein YbgE
AM681_RS06280	COG0824	Thioesterase
AM681_RS06285	COG0811	peptide transport
AM681_RS06290	COG0848	biopolymer transport protein
AM681_RS06295	COG3064	Membrane
AM681_RS06300	COG0823	Involved in the tonB-independent uptake of proteins
AM681_RS06305	COG2885	chlorophyll binding
AM681_RS06310	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM681_RS06355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM681_RS06365	COG1230	cation diffusion facilitator family transporter
AM681_RS06370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM681_RS06370	COG2205	protein histidine kinase activity
AM681_RS06375	COG2197	response regulator
AM681_RS06380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM681_RS06395	COG0588	phosphoglycerate mutase activity
AM681_RS06405	COG2017	converts alpha-aldose to the beta-anomer
AM681_RS06410	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AM681_RS06430	COG1119	ATPase activity
AM681_RS06435	COG3585	molybdate ion transport
AM681_RS06435	COG2005	Transcriptional regulator
AM681_RS06445	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM681_RS06450	COG4149	molybdate abc transporter
AM681_RS06460	COG0561	phosphatase activity
AM681_RS06465	COG2706	6-phosphogluconolactonase activity
AM681_RS06475	COG1881	PFAM PEBP family protein
AM681_RS06480	COG1230	cation diffusion facilitator family transporter
AM681_RS06530	COG0556	nucleotide-excision repair
AM681_RS06535	COG4628	conserved protein (DUF2132)
AM681_RS06540	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM681_RS06545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM681_RS06550	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM681_RS06555	COG0315	cyclic pyranopterin monophosphate synthase activity
AM681_RS06560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM681_RS06565	COG0314	molybdopterin synthase activity
AM681_RS06570	COG0670	Belongs to the BI1 family
AM681_RS06575	COG0842	Transport permease protein
AM681_RS06580	COG0842	Transport permease protein
AM681_RS06585	COG1131	(ABC) transporter
AM681_RS06590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS06595	COG1309	transcriptional regulator
AM681_RS06600	COG0513	Belongs to the DEAD box helicase family
AM681_RS06610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM681_RS06615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM681_RS06625	COG3842	ATPase activity
AM681_RS06635	COG1840	ABC-type Fe3 transport system, periplasmic component
AM681_RS06640	COG2271	Major facilitator Superfamily
AM681_RS06655	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM681_RS06670	COG0583	DNA-binding transcription factor activity
AM681_RS06690	COG0583	DNA-binding transcription factor activity
AM681_RS06700	COG0586	Pfam SNARE associated Golgi protein
AM681_RS06710	COG4977	sequence-specific DNA binding
AM681_RS06715	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM681_RS06720	COG1686	Belongs to the peptidase S11 family
AM681_RS06750	COG2354	Protein conserved in bacteria
AM681_RS06760	COG3692	DNA binding
AM681_RS06765	COG1464	Belongs to the NlpA lipoprotein family
AM681_RS06775	COG0456	acetyltransferase
AM681_RS06795	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM681_RS06805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM681_RS06810	COG0277	FAD linked oxidase domain protein
AM681_RS06825	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM681_RS06835	COG0436	Aminotransferase
AM681_RS06845	COG1472	Belongs to the glycosyl hydrolase 3 family
AM681_RS06855	COG2345	Transcriptional regulator
AM681_RS06870	COG2134	cdp-diacylglycerol pyrophosphatase
AM681_RS06880	COG1192	Involved in chromosome partitioning
AM681_RS06890	COG0583	DNA-binding transcription factor activity
AM681_RS06900	COG1070	Carbohydrate kinase
AM681_RS06905	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM681_RS06910	COG0697	spore germination
AM681_RS06960	COG1309	transcriptional regulator
AM681_RS06970	COG1464	Belongs to the NlpA lipoprotein family
AM681_RS06975	COG2011	ABC-type metal ion transport system permease component
AM681_RS06980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM681_RS06985	COG0519	Catalyzes the synthesis of GMP from XMP
AM681_RS07000	COG2084	Dehydrogenase
AM681_RS07015	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM681_RS07030	COG4807	Protein conserved in bacteria
AM681_RS07050	COG1802	Transcriptional regulator
AM681_RS07070	COG1129	ABC transporter
AM681_RS07095	COG0583	DNA-binding transcription factor activity
AM681_RS07100	COG2897	thiosulfate sulfurtransferase activity
AM681_RS07105	COG0494	nUDIX hydrolase
AM681_RS07110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM681_RS07120	COG0625	glutathione transferase activity
AM681_RS07130	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AM681_RS07140	COG1335	isochorismatase
AM681_RS07145	COG0583	DNA-binding transcription factor activity
AM681_RS07165	COG1732	Glycine betaine
AM681_RS07170	COG1174	glycine betaine transport
AM681_RS07175	COG1125	glycine betaine transport
AM681_RS07180	COG1174	glycine betaine transport
AM681_RS07205	COG0583	DNA-binding transcription factor activity
AM681_RS07210	COG0697	spore germination
AM681_RS07255	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AM681_RS07270	COG0625	glutathione transferase activity
AM681_RS07275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM681_RS07280	COG1942	4-Oxalocrotonate Tautomerase
AM681_RS07290	COG1522	sequence-specific DNA binding
AM681_RS07295	COG0697	spore germination
AM681_RS07320	COG2079	MmgE PrpD family protein
AM681_RS07325	COG1280	lysine exporter protein (LysE YggA)
AM681_RS07335	COG0477	Major facilitator Superfamily
AM681_RS07345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM681_RS07365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM681_RS07370	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AM681_RS07380	COG1309	transcriptional regulator
AM681_RS07395	COG0668	transmembrane transport
AM681_RS07400	COG1126	abc transporter atp-binding protein
AM681_RS07405	COG0765	amino acid transport
AM681_RS07410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM681_RS07420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM681_RS07435	COG2731	YhcH YjgK YiaL family protein
AM681_RS07445	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM681_RS07450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM681_RS07465	COG2610	gluconate transmembrane transporter activity
AM681_RS07470	COG3622	Belongs to the hyi family
AM681_RS07475	COG0235	Class ii aldolase
AM681_RS07480	COG3395	kinase activity
AM681_RS07485	COG2084	Dehydrogenase
AM681_RS07490	COG1349	DNA-binding transcription factor activity
AM681_RS07525	COG3188	usher protein
AM681_RS07540	COG5002	protein histidine kinase activity
AM681_RS07545	COG0745	RESPONSE REGULATOR receiver
AM681_RS07550	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM681_RS07555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM681_RS07570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM681_RS07575	COG1309	transcriptional regulator
AM681_RS07580	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS07585	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM681_RS07590	COG0069	glutamate synthase activity
AM681_RS07600	COG2200	EAL domain
AM681_RS07610	COG3121	Chaperone
AM681_RS07615	COG3188	usher protein
AM681_RS07630	COG4804	nuclease activity
AM681_RS07635	COG2003	Belongs to the UPF0758 family
AM681_RS07650	COG1475	DNA binding
AM681_RS07670	COG5489	Protein of unknown function (DUF736)
AM681_RS07720	COG4959	Type IV secretory pathway protease TraF
AM681_RS07745	COG1127	ABC transporter
AM681_RS07750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM681_RS07785	COG0583	DNA-binding transcription factor activity
AM681_RS07795	COG2076	Multidrug Resistance protein
AM681_RS07825	COG4962	Type ii secretion system protein e
AM681_RS07830	COG3838	Conjugal transfer protein Trbc
AM681_RS07840	COG3451	type IV secretory pathway VirB4
AM681_RS07855	COG3846	protein secretion by the type IV secretion system
AM681_RS07880	COG2207	Transcriptional regulator
AM681_RS07880	COG3708	Transcriptional regulator
AM681_RS07885	COG0579	oxidoreductase
AM681_RS07895	COG0625	glutathione transferase activity
AM681_RS07900	COG0640	Transcriptional regulator
AM681_RS07915	COG1335	isochorismatase
AM681_RS07920	COG0583	DNA-binding transcription factor activity
AM681_RS07935	COG3811	Belongs to the UPF0386 family
AM681_RS07940	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AM681_RS07950	COG0583	DNA-binding transcription factor activity
AM681_RS07965	COG1942	4-Oxalocrotonate Tautomerase
AM681_RS07990	COG0488	(ABC) transporter
AM681_RS08000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM681_RS08005	COG0303	'Molybdopterin
AM681_RS08020	COG4172	Belongs to the ABC transporter superfamily
AM681_RS08025	COG0747	negative chemotaxis
AM681_RS08030	COG0601	transmembrane transport
AM681_RS08035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM681_RS08055	COG0583	DNA-binding transcription factor activity
AM681_RS08060	COG0477	Major facilitator Superfamily
AM681_RS08065	COG0302	gtp cyclohydrolase
AM681_RS08070	COG2311	Membrane
AM681_RS08075	COG1609	Transcriptional regulator
AM681_RS08095	COG2949	membrane
AM681_RS08105	COG0281	malic enzyme
AM681_RS08110	COG0295	cytidine deaminase activity
AM681_RS08115	COG1346	cytolysis
AM681_RS08120	COG1380	Effector of murein hydrolase LrgA
AM681_RS08125	COG2814	Major facilitator Superfamily
AM681_RS08135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM681_RS08135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM681_RS08140	COG0489	protein tyrosine kinase activity
AM681_RS08150	COG0572	uridine kinase
AM681_RS08155	COG0717	Belongs to the dCTP deaminase family
AM681_RS08160	COG2982	Protein involved in outer membrane biogenesis
AM681_RS08165	COG3069	C4-dicarboxylate transmembrane transporter activity
AM681_RS08170	COG1253	flavin adenine dinucleotide binding
AM681_RS08175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM681_RS08190	COG3206	protein involved in exopolysaccharide biosynthesis
AM681_RS08190	COG0489	protein tyrosine kinase activity
AM681_RS08200	COG1215	transferase activity, transferring glycosyl groups
AM681_RS08210	COG0438	transferase activity, transferring glycosyl groups
AM681_RS08240	COG3206	protein involved in exopolysaccharide biosynthesis
AM681_RS08240	COG0489	protein tyrosine kinase activity
AM681_RS08265	COG0438	transferase activity, transferring glycosyl groups
AM681_RS08360	COG1216	Glycosyl transferase, family 2
AM681_RS08360	COG1442	glycosyl transferase family 8
AM681_RS08375	COG1216	Glycosyl transferase, family 2
AM681_RS08380	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM681_RS08390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM681_RS08395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM681_RS08395	COG0140	phosphoribosyl-ATP diphosphatase activity
AM681_RS08400	COG0107	imidazoleglycerol-phosphate synthase activity
AM681_RS08405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM681_RS08415	COG0131	Imidazoleglycerol-phosphate dehydratase
AM681_RS08415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM681_RS08420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM681_RS08430	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM681_RS08440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM681_RS08445	COG0583	DNA-binding transcription factor activity
AM681_RS08450	COG2814	Major facilitator Superfamily
AM681_RS08465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM681_RS08470	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM681_RS08475	COG3153	acetyltransferase
AM681_RS08475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM681_RS08480	COG0598	Magnesium transport protein CorA
AM681_RS08490	COG2133	pyrroloquinoline quinone binding
AM681_RS08495	COG0625	glutathione transferase activity
AM681_RS08515	COG0626	cystathionine gamma-synthase activity
AM681_RS08525	COG1686	Belongs to the peptidase S11 family
AM681_RS08530	COG1760	l-serine dehydratase
AM681_RS08535	COG0814	amino acid
AM681_RS08540	COG1349	DNA-binding transcription factor activity
AM681_RS08545	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM681_RS08555	COG0671	phosphoesterase, PA-phosphatase related
AM681_RS08570	COG4574	serine-type endopeptidase inhibitor activity
AM681_RS08580	COG3395	kinase activity
AM681_RS08585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM681_RS08640	COG2985	domain, Protein
AM681_RS08640	COG0569	domain protein
AM681_RS08660	COG0189	ligase activity
AM681_RS08670	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM681_RS08675	COG3842	ATPase activity
AM681_RS08680	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM681_RS08685	COG1177	transmembrane transport
AM681_RS08695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM681_RS08705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM681_RS08720	COG4160	amino acid transport
AM681_RS08725	COG4215	(ABC) transporter
AM681_RS08730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM681_RS08735	COG1126	abc transporter atp-binding protein
AM681_RS08745	COG0393	Putative heavy-metal-binding
AM681_RS08755	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM681_RS08760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM681_RS08765	COG0702	epimerase
AM681_RS08775	COG1737	Transcriptional regulator
AM681_RS08780	COG2190	(PTS) system
AM681_RS08780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM681_RS08780	COG1263	PTS System
AM681_RS08785	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AM681_RS08790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM681_RS08795	COG0028	Belongs to the TPP enzyme family
AM681_RS08800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM681_RS08805	COG1151	hydroxylamine reductase activity
AM681_RS08810	COG2431	L-lysine efflux transmembrane transporter activity
AM681_RS08815	COG3593	DNA synthesis involved in DNA repair
AM681_RS08820	COG2990	Protein conserved in bacteria
AM681_RS08825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS08835	COG1278	Cold shock
AM681_RS08840	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM681_RS08845	COG0542	response to heat
AM681_RS08850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM681_RS08855	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM681_RS08860	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM681_RS08875	COG0583	DNA-binding transcription factor activity
AM681_RS08880	COG0492	ferredoxin-NADP+ reductase activity
AM681_RS08890	COG3107	peptidoglycan biosynthetic process
AM681_RS08890	COG1674	ftsk spoiiie
AM681_RS08895	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM681_RS08900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM681_RS08905	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM681_RS08915	COG2814	Major facilitator Superfamily
AM681_RS08920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM681_RS08925	COG1882	Formate acetyltransferase
AM681_RS08930	COG2116	formate transmembrane transporter activity
AM681_RS08935	COG1944	ATP diphosphatase activity
AM681_RS08940	COG0252	asparaginase activity
AM681_RS08945	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AM681_RS08950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM681_RS08955	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM681_RS08960	COG0539	negative regulation of cytoplasmic translation
AM681_RS08970	COG2333	competence protein COMEC
AM681_RS08970	COG0658	competence protein
AM681_RS08975	COG1132	(ABC) transporter
AM681_RS08980	COG1663	tetraacyldisaccharide 4'-kinase activity
AM681_RS08985	COG5383	Protein conserved in bacteria
AM681_RS08995	COG1278	Cold shock
AM681_RS09000	COG3214	Protein conserved in bacteria
AM681_RS09005	COG2835	tetraacyldisaccharide 4'-kinase activity
AM681_RS09010	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM681_RS09015	COG3173	Aminoglycoside phosphotransferase
AM681_RS09020	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM681_RS09025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM681_RS09030	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AM681_RS09040	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM681_RS09045	COG2989	Protein conserved in bacteria
AM681_RS09050	COG3108	Peptidase M15
AM681_RS09055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM681_RS09060	COG1448	Aminotransferase
AM681_RS09070	COG0017	Asparaginyl-tRNA synthetase
AM681_RS09075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AM681_RS09080	COG3706	GGDEF domain
AM681_RS09085	COG0308	aminopeptidase N
AM681_RS09095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM681_RS09100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM681_RS09105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM681_RS09110	COG0431	NADPH-dependent FMN reductase
AM681_RS09115	COG0167	dihydroorotate dehydrogenase activity
AM681_RS09125	COG3217	Mosc domain protein beta barrel domain protein
AM681_RS09125	COG0633	Ferredoxin
AM681_RS09130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM681_RS09130	COG0116	Belongs to the methyltransferase superfamily
AM681_RS09135	COG0488	(ABC) transporter
AM681_RS09140	COG2995	paraquat-inducible protein a
AM681_RS09145	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM681_RS09145	COG3008	intermembrane lipid transfer
AM681_RS09150	COG3009	Protein conserved in bacteria
AM681_RS09155	COG3130	regulation of translation
AM681_RS09160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM681_RS09170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM681_RS09175	COG1067	ATP-dependent peptidase activity
AM681_RS09195	COG3070	regulator of competence-specific genes
AM681_RS09200	COG1289	transmembrane transporter activity
AM681_RS09205	COG3304	Inner membrane component domain
AM681_RS09210	COG0210	DNA helicase
AM681_RS09215	COG1803	Methylglyoxal synthase
AM681_RS09225	COG1832	CoA-binding protein
AM681_RS09230	COG3785	DNA binding
AM681_RS09235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM681_RS09240	COG1254	Belongs to the acylphosphatase family
AM681_RS09245	COG2920	part of a sulfur-relay system
AM681_RS09250	COG0670	Belongs to the BI1 family
AM681_RS09290	COG3121	Chaperone
AM681_RS09295	COG3188	usher protein
AM681_RS09305	COG0789	Transcriptional regulator
AM681_RS09310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS09315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM681_RS09325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM681_RS09335	COG0655	NAD(P)H dehydrogenase (quinone) activity
AM681_RS09355	COG1113	amino acid transport
AM681_RS09365	COG0586	Pfam SNARE associated Golgi protein
AM681_RS09370	COG2271	Major facilitator Superfamily
AM681_RS09390	COG1024	Enoyl-CoA hydratase
AM681_RS09395	COG2814	Major facilitator Superfamily
AM681_RS09400	COG0156	8-amino-7-oxononanoate synthase activity
AM681_RS09405	COG0183	Belongs to the thiolase family
AM681_RS09410	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM681_RS09415	COG2197	response regulator
AM681_RS09420	COG0589	response to stress
AM681_RS09435	COG0531	amino acid
AM681_RS09440	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS09445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM681_RS09470	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM681_RS09485	COG3136	membrane protein required for alginate biosynthesis
AM681_RS09495	COG2197	response regulator
AM681_RS09500	COG0322	excinuclease ABC activity
AM681_RS09535	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM681_RS09580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS09585	COG0322	excinuclease ABC activity
AM681_RS09620	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AM681_RS09625	COG2943	transferase activity, transferring hexosyl groups
AM681_RS09630	COG5645	(Lipo)protein
AM681_RS09645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM681_RS09655	COG0640	Transcriptional regulator
AM681_RS09670	COG0346	lactoylglutathione lyase activity
AM681_RS09680	COG2814	Major facilitator Superfamily
AM681_RS09690	COG1560	Kdo2-lipid A biosynthetic process
AM681_RS09700	COG1054	Belongs to the UPF0176 family
AM681_RS09705	COG2353	YceI-like domain
AM681_RS09710	COG3038	cytochrome b561
AM681_RS09715	COG0628	permease
AM681_RS09725	COG4264	IucA IucC family
AM681_RS09730	COG4774	siderophore transport
AM681_RS09735	COG0019	diaminopimelate decarboxylase activity
AM681_RS09740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM681_RS09750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AM681_RS09755	COG2814	Major facilitator Superfamily
AM681_RS09765	COG1104	cysteine desulfurase activity
AM681_RS09820	COG0418	dihydroorotase activity
AM681_RS09825	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM681_RS09830	COG1530	ribonuclease E activity
AM681_RS09840	COG0564	pseudouridine synthase activity
AM681_RS09850	COG1399	metal-binding, possibly nucleic acid-binding protein
AM681_RS09855	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM681_RS09860	COG0416	fatty acid biosynthetic process
AM681_RS09865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM681_RS09870	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM681_RS09880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM681_RS09885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM681_RS09890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM681_RS09895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM681_RS09900	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM681_RS09905	COG0470	DNA polymerase III
AM681_RS09910	COG0084	hydrolase, TatD family'
AM681_RS09915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM681_RS09915	COG1263	PTS System
AM681_RS10055	COG4695	Portal protein
AM681_RS10075	COG0464	growth
AM681_RS10125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM681_RS10165	COG1321	iron dependent repressor
AM681_RS10170	COG1914	H( )-stimulated, divalent metal cation uptake system
AM681_RS10175	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS10180	COG1733	regulation of RNA biosynthetic process
AM681_RS10190	COG0537	adenosine 5'-monophosphoramidase activity
AM681_RS10195	COG5633	Lipoprotein
AM681_RS10200	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AM681_RS10205	COG0510	thiamine kinase activity
AM681_RS10215	COG3150	esterase
AM681_RS10220	COG1252	NADH dehydrogenase
AM681_RS10225	COG3134	Outer membrane lipoprotein
AM681_RS10240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS10245	COG2207	Transcriptional regulator
AM681_RS10245	COG3708	Transcriptional regulator
AM681_RS10285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM681_RS10290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AM681_RS10295	COG3381	protein complex oligomerization
AM681_RS10300	COG2979	Protein of unknown function (DUF533)
AM681_RS10305	COG1770	oligopeptidase
AM681_RS10310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM681_RS10335	COG1528	Iron-storage protein
AM681_RS10340	COG2372	response to copper ion
AM681_RS10345	COG1276	copper resistance
AM681_RS10385	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM681_RS10395	COG3655	Transcriptional regulator
AM681_RS10420	COG4565	transcriptional regulatory protein
AM681_RS10425	COG3290	protein histidine kinase activity
AM681_RS10440	COG1129	ABC transporter
AM681_RS10445	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM681_RS10465	COG0579	oxidoreductase
AM681_RS10480	COG2358	TRAP transporter, solute receptor (TAXI family
AM681_RS10485	COG1464	Belongs to the NlpA lipoprotein family
AM681_RS10495	COG0589	response to stress
AM681_RS10500	COG3408	Glycogen debranching enzyme
AM681_RS10500	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AM681_RS10510	COG1609	Transcriptional regulator
AM681_RS10515	COG3250	beta-galactosidase activity
AM681_RS10520	COG2731	YhcH YjgK YiaL family protein
AM681_RS10525	COG0531	amino acid
AM681_RS10530	COG0640	Transcriptional regulator
AM681_RS10540	COG0740	serine-type endopeptidase activity
AM681_RS10565	COG3121	Chaperone
AM681_RS10590	COG0012	GTP binding
AM681_RS10595	COG0659	secondary active sulfate transmembrane transporter activity
AM681_RS10600	COG0193	aminoacyl-tRNA hydrolase activity
AM681_RS10610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM681_RS10615	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM681_RS10620	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM681_RS10625	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM681_RS10630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM681_RS10635	COG2890	protein-(glutamine-N5) methyltransferase activity
AM681_RS10640	COG3094	Invasion gene expression up-regulator, SirB
AM681_RS10645	COG2912	Transglutaminase-like superfamily
AM681_RS10650	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM681_RS10655	COG0659	secondary active sulfate transmembrane transporter activity
AM681_RS10660	COG4702	Belongs to the UPF0303 family
AM681_RS10665	COG3706	GGDEF domain
AM681_RS10670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM681_RS10685	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM681_RS10695	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM681_RS10720	COG1177	transmembrane transport
AM681_RS10735	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM681_RS10755	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM681_RS10765	COG2850	peptidyl-arginine hydroxylation
AM681_RS10775	COG0745	RESPONSE REGULATOR receiver
AM681_RS10780	COG1397	ADP-ribosylglycohydrolase
AM681_RS10785	COG2188	Transcriptional regulator
AM681_RS10800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM681_RS10805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM681_RS10810	COG2915	High frequency lysogenization protein hflD homolog
AM681_RS10820	COG0482	sulfurtransferase activity
AM681_RS10835	COG1187	pseudouridine synthase activity
AM681_RS10840	COG0538	isocitrate dehydrogenase activity
AM681_RS10930	COG1278	Cold shock
AM681_RS10940	COG1335	isochorismatase
AM681_RS10945	COG0589	response to stress
AM681_RS10950	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS10955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM681_RS10960	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS10965	COG1396	sequence-specific DNA binding
AM681_RS10965	COG1917	Cupin 2, conserved barrel domain protein
AM681_RS10970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM681_RS10975	COG0174	glutamine synthetase
AM681_RS10985	COG0531	amino acid
AM681_RS11015	COG1605	Chorismate mutase
AM681_RS11030	COG1228	amidohydrolase
AM681_RS11040	COG0402	S-adenosylhomocysteine deaminase activity
AM681_RS11060	COG2211	Major facilitator Superfamily
AM681_RS11065	COG0477	Major facilitator Superfamily
AM681_RS11085	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AM681_RS11090	COG3493	citrate carrier protein
AM681_RS11100	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM681_RS11170	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AM681_RS11170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM681_RS11175	COG3008	intermembrane lipid transfer
AM681_RS11180	COG2995	paraquat-inducible protein a
AM681_RS11185	COG1956	GAF domain-containing protein
AM681_RS11190	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM681_RS11195	COG0793	Belongs to the peptidase S41A family
AM681_RS11215	COG1120	ATPase activity
AM681_RS11220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM681_RS11225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM681_RS11230	COG0501	Belongs to the peptidase M48B family
AM681_RS11235	COG2814	Major facilitator Superfamily
AM681_RS11240	COG1414	Transcriptional regulator
AM681_RS11265	COG2188	Transcriptional regulator
AM681_RS11280	COG1823	symporter activity
AM681_RS11285	COG1988	membrane-bound metal-dependent
AM681_RS11290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM681_RS11305	COG3001	Fructosamine kinase
AM681_RS11310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM681_RS11315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM681_RS11320	COG1121	(ABC) transporter
AM681_RS11325	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM681_RS11355	COG0814	amino acid
AM681_RS11395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM681_RS11405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM681_RS11410	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM681_RS11420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM681_RS11440	COG4139	cobalamin transport
AM681_RS11445	COG0386	Belongs to the glutathione peroxidase family
AM681_RS11450	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AM681_RS11455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM681_RS11460	COG1215	transferase activity, transferring glycosyl groups
AM681_RS11465	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM681_RS11465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM681_RS11470	COG0726	polysaccharide deacetylase
AM681_RS11475	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM681_RS11480	COG2076	Multidrug Resistance protein
AM681_RS11485	COG2076	Multidrug Resistance protein
AM681_RS11490	COG0791	NLP P60 protein
AM681_RS11495	COG0095	Lipoate-protein ligase
AM681_RS11515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM681_RS11520	COG4558	Periplasmic binding protein
AM681_RS11525	COG3720	iron ion transport
AM681_RS11540	COG0386	Belongs to the glutathione peroxidase family
AM681_RS11545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM681_RS11550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AM681_RS11560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM681_RS11560	COG0574	Belongs to the PEP-utilizing enzyme family
AM681_RS11570	COG0628	permease
AM681_RS11575	COG0247	lactate metabolic process
AM681_RS11575	COG0277	FAD linked oxidase domain protein
AM681_RS11580	COG2050	protein possibly involved in aromatic compounds catabolism
AM681_RS11590	COG0316	Belongs to the HesB IscA family
AM681_RS11595	COG0719	Fe-S assembly protein
AM681_RS11600	COG0396	ATPase activity
AM681_RS11605	COG0719	Fe-S assembly protein
AM681_RS11610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM681_RS11615	COG2166	iron-sulfur cluster assembly
AM681_RS11620	COG1388	LysM domain
AM681_RS11620	COG1376	ErfK ybiS ycfS ynhG family protein
AM681_RS11630	COG0469	pyruvate kinase activity
AM681_RS11655	COG0534	Mate efflux family protein
AM681_RS11660	COG0307	riboflavin synthase, alpha
AM681_RS11670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM681_RS11675	COG2814	Major facilitator Superfamily
AM681_RS11680	COG0583	DNA-binding transcription factor activity
AM681_RS11685	COG1609	Transcriptional regulator
AM681_RS11700	COG0791	NLP P60 protein
AM681_RS11705	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM681_RS11715	COG0346	lactoylglutathione lyase activity
AM681_RS11720	COG1902	pentaerythritol trinitrate reductase activity
AM681_RS11725	COG1309	transcriptional regulator
AM681_RS11730	COG2194	sulfuric ester hydrolase activity
AM681_RS11740	COG0583	DNA-binding transcription factor activity
AM681_RS11745	COG3313	Fe-S protein
AM681_RS11750	COG4989	oxidoreductase activity
AM681_RS11755	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM681_RS11765	COG1289	transmembrane transporter activity
AM681_RS11770	COG1566	PFAM secretion protein HlyD family protein
AM681_RS11780	COG1846	Transcriptional regulator
AM681_RS11785	COG3133	Outer membrane lipoprotein
AM681_RS11795	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM681_RS11805	COG0259	pyridoxamine-phosphate oxidase activity
AM681_RS11810	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM681_RS11820	COG0625	glutathione transferase activity
AM681_RS11835	COG1418	mRNA catabolic process
AM681_RS11870	COG4122	O-methyltransferase activity
AM681_RS11875	COG3135	benzoate transporter
AM681_RS11880	COG1396	sequence-specific DNA binding
AM681_RS11885	COG1505	serine-type exopeptidase activity
AM681_RS11890	COG3104	oligopeptide transport
AM681_RS11895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM681_RS11905	COG4659	FMN binding
AM681_RS11915	COG3708	Transcriptional regulator
AM681_RS11915	COG2207	Transcriptional regulator
AM681_RS11920	COG4656	Part of a membrane complex involved in electron transport
AM681_RS11925	COG2878	Part of a membrane complex involved in electron transport
AM681_RS11930	COG4657	Part of a membrane complex involved in electron transport
AM681_RS11940	COG0673	inositol 2-dehydrogenase activity
AM681_RS11945	COG0385	Bile acid
AM681_RS11955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM681_RS11960	COG1349	DNA-binding transcription factor activity
AM681_RS11965	COG0494	nUDIX hydrolase
AM681_RS11975	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM681_RS11980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM681_RS11980	COG1263	PTS System
AM681_RS11985	COG1609	Transcriptional regulator
AM681_RS12000	COG0583	DNA-binding transcription factor activity
AM681_RS12010	COG5339	Protein conserved in bacteria
AM681_RS12030	COG0114	fumarate hydratase activity
AM681_RS12045	COG2378	regulation of single-species biofilm formation
AM681_RS12065	COG1649	PFAM Uncharacterised BCR, COG1649
AM681_RS12070	COG2814	Major facilitator Superfamily
AM681_RS12075	COG0583	DNA-binding transcription factor activity
AM681_RS12080	COG1940	carbohydrate kinase activity
AM681_RS12085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM681_RS12095	COG0789	Transcriptional regulator
AM681_RS12115	COG0477	Major facilitator Superfamily
AM681_RS12130	COG1742	UPF0060 membrane protein
AM681_RS12135	COG4221	oxidoreductase activity
AM681_RS12145	COG4772	TonB-dependent receptor
AM681_RS12150	COG3712	iron ion homeostasis
AM681_RS12155	COG1595	DNA-templated transcription, initiation
AM681_RS12160	COG0402	S-adenosylhomocysteine deaminase activity
AM681_RS12175	COG0339	signal peptide processing
AM681_RS12180	COG2271	Major facilitator Superfamily
AM681_RS12185	COG1335	isochorismatase
AM681_RS12190	COG3473	Maleate cis-trans isomerase
AM681_RS12195	COG0596	Alpha beta hydrolase
AM681_RS12200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM681_RS12205	COG2309	aminopeptidase activity
AM681_RS12210	COG1846	Transcriptional regulator
AM681_RS12215	COG2080	2 iron, 2 sulfur cluster binding
AM681_RS12220	COG2010	Cytochrome c
AM681_RS12220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM681_RS12275	COG1073	alpha beta
AM681_RS12280	COG2140	Oxalate decarboxylase
AM681_RS12290	COG2059	Chromate
AM681_RS12315	COG0596	Alpha beta hydrolase
AM681_RS12380	COG3209	COG3209 Rhs family protein
AM681_RS12380	COG4104	PAAR repeat-containing protein
AM681_RS12445	COG2814	Major facilitator Superfamily
AM681_RS12465	COG0768	penicillin binding
AM681_RS12490	COG0840	transmembrane signaling receptor activity
AM681_RS12515	COG0583	DNA-binding transcription factor activity
AM681_RS12525	COG2814	Major facilitator Superfamily
AM681_RS12535	COG1349	DNA-binding transcription factor activity
AM681_RS12540	COG0673	inositol 2-dehydrogenase activity
AM681_RS12545	COG2814	Major facilitator Superfamily
AM681_RS12565	COG1309	transcriptional regulator
AM681_RS12580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM681_RS12585	COG2862	Uncharacterized protein family, UPF0114
AM681_RS12590	COG2814	Major facilitator Superfamily
AM681_RS12595	COG0583	DNA-binding transcription factor activity
AM681_RS12605	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM681_RS12615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM681_RS12615	COG3453	Protein conserved in bacteria
AM681_RS12625	COG1064	alcohol dehydrogenase
AM681_RS12635	COG3284	Transcriptional regulator
AM681_RS12645	COG2814	Major facilitator Superfamily
AM681_RS12650	COG3300	MHYT domain
AM681_RS12650	COG5001	Diguanylate cyclase
AM681_RS12695	COG0583	DNA-binding transcription factor activity
AM681_RS12705	COG0076	glutamate decarboxylase activity
AM681_RS12710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM681_RS12715	COG1902	pentaerythritol trinitrate reductase activity
AM681_RS12715	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM681_RS12725	COG0148	phosphopyruvate hydratase activity
AM681_RS12735	COG1227	inorganic diphosphatase activity
AM681_RS12740	COG0058	SHG alpha-glucan phosphorylase activity
AM681_RS12765	COG5002	protein histidine kinase activity
AM681_RS12765	COG3447	MASE1 domain protein
AM681_RS12765	COG5001	Diguanylate cyclase
AM681_RS12770	COG3300	MHYT domain
AM681_RS12770	COG5001	Diguanylate cyclase
AM681_RS12775	COG3250	beta-galactosidase activity
AM681_RS12780	COG2205	protein histidine kinase activity
AM681_RS12780	COG5002	protein histidine kinase activity
AM681_RS12780	COG0784	Response regulator, receiver
AM681_RS12825	COG0583	DNA-binding transcription factor activity
AM681_RS12855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM681_RS12865	COG1063	alcohol dehydrogenase
AM681_RS12890	COG4221	oxidoreductase activity
AM681_RS12895	COG4221	oxidoreductase activity
AM681_RS12910	COG1082	Xylose isomerase domain protein TIM barrel
AM681_RS12915	COG0673	inositol 2-dehydrogenase activity
AM681_RS12940	COG2801	Transposase and inactivated derivatives
AM681_RS12965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM681_RS13005	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM681_RS13010	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM681_RS13015	COG1733	regulation of RNA biosynthetic process
AM681_RS13030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM681_RS13035	COG0318	PFAM AMP-dependent synthetase and ligase
AM681_RS13040	COG0693	protein deglycase activity
AM681_RS13055	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AM681_RS13060	COG2957	Belongs to the agmatine deiminase family
AM681_RS13065	COG0583	DNA-binding transcription factor activity
AM681_RS13080	COG1349	DNA-binding transcription factor activity
AM681_RS13095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM681_RS13100	COG3192	ethanolamine utilization protein
AM681_RS13130	COG0778	Nitroreductase
AM681_RS13155	COG1737	Transcriptional regulator
AM681_RS13160	COG2723	6-phospho-beta-galactosidase activity
AM681_RS13165	COG3048	D-serine ammonia-lyase activity
AM681_RS13180	COG5507	3-demethylubiquinone-9 3-methyltransferase
AM681_RS13185	COG2199	diguanylate cyclase activity
AM681_RS13210	COG1196	nuclear chromosome segregation
AM681_RS13210	COG3264	Mechanosensitive ion channel
AM681_RS13215	COG0488	(ABC) transporter
AM681_RS13230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM681_RS13240	COG2239	Acts as a magnesium transporter
AM681_RS13275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM681_RS13280	COG0697	spore germination
AM681_RS13330	COG3158	transport of potassium into the cell
AM681_RS13335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM681_RS13340	COG1116	anion transmembrane transporter activity
AM681_RS13420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM681_RS13440	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM681_RS13445	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AM681_RS13470	COG1175	transmembrane transport
AM681_RS13475	COG0395	ABC-type sugar transport system, permease component
AM681_RS13480	COG3842	ATPase activity
AM681_RS13485	COG0673	inositol 2-dehydrogenase activity
AM681_RS13490	COG1940	carbohydrate kinase activity
AM681_RS13495	COG1349	DNA-binding transcription factor activity
AM681_RS13500	COG2222	sugar isomerase
AM681_RS13515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM681_RS13530	COG0589	response to stress
AM681_RS13535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM681_RS13540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM681_RS13550	COG0531	amino acid
AM681_RS13575	COG0745	RESPONSE REGULATOR receiver
AM681_RS13580	COG2205	protein histidine kinase activity
AM681_RS13585	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AM681_RS13590	COG2267	carboxylic ester hydrolase activity
AM681_RS13600	COG3591	Belongs to the peptidase S1B family
AM681_RS13605	COG2207	Transcriptional regulator
AM681_RS13610	COG2814	Major facilitator Superfamily
AM681_RS13615	COG1643	Atp-dependent helicase
AM681_RS13620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM681_RS13625	COG3784	Protein of unknown function (DUF1318)
AM681_RS13635	COG2911	Protein conserved in bacteria
AM681_RS13640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM681_RS13645	COG3187	Heat shock protein
AM681_RS13650	COG3042	response to heat
AM681_RS13660	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM681_RS13660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM681_RS13660	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM681_RS13660	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM681_RS13670	COG0037	tRNA processing
AM681_RS13700	COG4166	transmembrane transport
AM681_RS13710	COG2866	Carboxypeptidase
AM681_RS13715	COG4948	Mandelate Racemase Muconate Lactonizing
AM681_RS13720	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM681_RS13730	COG3768	UPF0283 membrane protein
AM681_RS13735	COG3106	COG3106 Predicted ATPase
AM681_RS13745	COG1983	PspC domain protein
AM681_RS13755	COG1842	Phage shock protein A
AM681_RS13760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM681_RS13785	COG1469	GTP cyclohydrolase I activity
AM681_RS13800	COG4171	peptide transport system, permease
AM681_RS13805	COG4172	Belongs to the ABC transporter superfamily
AM681_RS13810	COG4172	Belongs to the ABC transporter superfamily
AM681_RS13830	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM681_RS13830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM681_RS13845	COG0243	molybdopterin cofactor binding
AM681_RS13860	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AM681_RS13865	COG0477	Major facilitator Superfamily
AM681_RS13870	COG1473	amidohydrolase
AM681_RS13875	COG1966	Carbon starvation protein
AM681_RS13880	COG0859	PFAM glycosyl transferase family 9
AM681_RS13890	COG3210	domain, Protein
AM681_RS13905	COG1196	nuclear chromosome segregation
AM681_RS13905	COG3264	Mechanosensitive ion channel
AM681_RS13990	COG2831	hemolysin activation secretion protein
AM681_RS13995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM681_RS14000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM681_RS14005	COG1882	Formate acetyltransferase
AM681_RS14010	COG1349	DNA-binding transcription factor activity
AM681_RS14020	COG0023	Translation Initiation Factor
AM681_RS14045	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM681_RS14050	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM681_RS14055	COG0671	phosphoesterase, PA-phosphatase related
AM681_RS14065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM681_RS14075	COG3039	Transposase
AM681_RS14085	COG0583	DNA-binding transcription factor activity
AM681_RS14105	COG0616	signal peptide processing
AM681_RS14110	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS14115	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM681_RS14120	COG1187	pseudouridine synthase activity
AM681_RS14140	COG4974	Belongs to the 'phage' integrase family
AM681_RS14210	COG0009	L-threonylcarbamoyladenylate synthase
AM681_RS14215	COG0613	PHP domain protein
AM681_RS14230	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM681_RS14240	COG0133	tryptophan synthase activity
AM681_RS14245	COG0159	tryptophan synthase activity
AM681_RS14260	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM681_RS14275	COG2917	probably involved in intracellular septation
AM681_RS14280	COG1607	acyl-coa hydrolase
AM681_RS14290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM681_RS14295	COG2350	Protein conserved in bacteria
AM681_RS14315	COG0783	Belongs to the Dps family
AM681_RS14325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM681_RS14330	COG3099	Belongs to the UPF0263 family
AM681_RS14340	COG0444	Belongs to the ABC transporter superfamily
AM681_RS14345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM681_RS14360	COG4166	transmembrane transport
AM681_RS14365	COG2095	MarC family integral membrane protein
AM681_RS14370	COG1454	alcohol dehydrogenase
AM681_RS14370	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS14400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM681_RS14405	COG0745	RESPONSE REGULATOR receiver
AM681_RS14410	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM681_RS14415	COG3012	SEC-C Motif Domain Protein
AM681_RS14420	COG0788	formyltetrahydrofolate deformylase activity
AM681_RS14455	COG0708	Exodeoxyribonuclease III
AM681_RS14460	COG0494	nUDIX hydrolase
AM681_RS14470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM681_RS14475	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AM681_RS14485	COG0778	Nitroreductase
AM681_RS14490	COG0616	signal peptide processing
AM681_RS14495	COG0252	asparaginase activity
AM681_RS14500	COG1335	isochorismatase
AM681_RS14510	COG3139	Protein of unknown function (DUF1315)
AM681_RS14515	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM681_RS14535	COG3713	MltA-interacting MipA family protein
AM681_RS14550	COG2766	serine protein kinase
AM681_RS14555	COG2718	Belongs to the UPF0229 family
AM681_RS14565	COG1595	DNA-templated transcription, initiation
AM681_RS14570	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AM681_RS14615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM681_RS14620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM681_RS14630	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM681_RS14635	COG2719	SpoVR family
AM681_RS14640	COG2186	Transcriptional regulator
AM681_RS14645	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM681_RS14650	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AM681_RS14695	COG2983	Belongs to the UPF0260 family
AM681_RS14700	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM681_RS14705	COG2951	lytic endotransglycosylase activity
AM681_RS14710	COG3100	YcgL domain-containing protein
AM681_RS14715	COG0850	regulation of cytokinetic process
AM681_RS14720	COG2894	cell division
AM681_RS14725	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AM681_RS14730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM681_RS14735	COG0318	PFAM AMP-dependent synthetase and ligase
AM681_RS14740	COG3065	identical protein binding
AM681_RS14750	COG1199	ATP-dependent helicase activity
AM681_RS14755	COG0251	oxidation-reduction process
AM681_RS14760	COG2076	Multidrug Resistance protein
AM681_RS14765	COG2076	Multidrug Resistance protein
AM681_RS14770	COG0800	Aldolase
AM681_RS14775	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM681_RS14780	COG1737	Transcriptional regulator
AM681_RS14785	COG0469	pyruvate kinase activity
AM681_RS14800	COG1560	Kdo2-lipid A biosynthetic process
AM681_RS14805	COG0739	heme binding
AM681_RS14810	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM681_RS14815	COG1121	(ABC) transporter
AM681_RS14820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM681_RS14825	COG2255	four-way junction helicase activity
AM681_RS14830	COG0632	four-way junction helicase activity
AM681_RS14835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM681_RS14840	COG0217	transcriptional regulatory protein
AM681_RS14845	COG0494	nUDIX hydrolase
AM681_RS14850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM681_RS14860	COG1335	isochorismatase
AM681_RS14865	COG1801	Protein of unknown function DUF72
AM681_RS14870	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM681_RS14875	COG2226	methyltransferase
AM681_RS14880	COG0500	methyltransferase
AM681_RS14885	COG0545	Peptidyl-prolyl cis-trans isomerase
AM681_RS14895	COG3142	Participates in the control of copper homeostasis
AM681_RS14900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM681_RS14905	COG3102	Protein conserved in bacteria
AM681_RS14910	COG0018	arginyl-trna synthetase
AM681_RS14920	COG0673	inositol 2-dehydrogenase activity
AM681_RS14925	COG3132	Protein of unknown function, DUF480
AM681_RS14930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM681_RS14935	COG0477	Major facilitator Superfamily
AM681_RS14945	COG2999	glutathione oxidoreductase activity
AM681_RS14970	COG3097	Belongs to the UPF0267 family
AM681_RS14975	COG3141	response to X-ray
AM681_RS14980	COG0513	Belongs to the DEAD box helicase family
AM681_RS14990	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AM681_RS14995	COG3140	Belongs to the UPF0181 family
AM681_RS15000	COG1216	Glycosyl transferase, family 2
AM681_RS15010	COG0494	nUDIX hydrolase
AM681_RS15015	COG1760	l-serine dehydratase
AM681_RS15020	COG2200	EAL domain
AM681_RS15025	COG1253	flavin adenine dinucleotide binding
AM681_RS15030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM681_RS15030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS15035	COG3715	PTS system
AM681_RS15040	COG3716	PTS system mannose fructose sorbose family IID component
AM681_RS15045	COG4811	Protein of unknown function (DUF986)
AM681_RS15050	COG1971	Probably functions as a manganese efflux pump
AM681_RS15055	COG2226	methyltransferase
AM681_RS15060	COG1496	oxidoreductase activity
AM681_RS15095	COG1113	amino acid transport
AM681_RS15140	COG2207	Transcriptional regulator
AM681_RS15155	COG1652	LysM domain
AM681_RS15175	COG2988	succinylglutamate desuccinylase activity
AM681_RS15180	COG3724	N-succinylarginine dihydrolase activity
AM681_RS15185	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS15190	COG3138	arginine N-succinyltransferase
AM681_RS15195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM681_RS15205	COG4608	Belongs to the ABC transporter superfamily
AM681_RS15210	COG0444	Belongs to the ABC transporter superfamily
AM681_RS15220	COG0601	transmembrane transport
AM681_RS15230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM681_RS15235	COG1271	oxidase subunit
AM681_RS15240	COG1294	oxidase, subunit
AM681_RS15285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM681_RS15290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM681_RS15295	COG2181	nitrate reductase activity
AM681_RS15300	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM681_RS15305	COG1140	nitrate reductase beta subunit
AM681_RS15310	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM681_RS15350	COG0489	protein tyrosine kinase activity
AM681_RS15350	COG3206	protein involved in exopolysaccharide biosynthesis
AM681_RS15360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM681_RS15365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM681_RS15370	COG3710	Transcriptional regulator
AM681_RS15375	COG2223	nitrite transmembrane transporter activity
AM681_RS15380	COG3850	Histidine kinase
AM681_RS15385	COG2197	response regulator
AM681_RS15390	COG4932	domain protein
AM681_RS15395	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AM681_RS15405	COG0747	negative chemotaxis
AM681_RS15410	COG4608	Belongs to the ABC transporter superfamily
AM681_RS15415	COG0444	Belongs to the ABC transporter superfamily
AM681_RS15420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM681_RS15425	COG0601	transmembrane transport
AM681_RS15440	COG0583	DNA-binding transcription factor activity
AM681_RS15445	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM681_RS15450	COG4572	Cation transport regulator
AM681_RS15455	COG2375	cellular response to nickel ion
AM681_RS15460	COG0387	Pfam Sodium calcium exchanger
AM681_RS15470	COG1702	phosphate starvation-inducible protein PhoH
AM681_RS15480	COG2822	iron ion transport
AM681_RS15485	COG0672	)-iron permease
AM681_RS15495	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM681_RS15495	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM681_RS15495	COG0506	proline dehydrogenase activity
AM681_RS15500	COG1126	abc transporter atp-binding protein
AM681_RS15505	COG0765	amino acid transport
AM681_RS15510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM681_RS15515	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AM681_RS15525	COG1191	sigma factor activity
AM681_RS15560	COG0583	DNA-binding transcription factor activity
AM681_RS15575	COG1677	Flagellar hook-basal body complex protein FliE
AM681_RS15585	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM681_RS15590	COG1317	bacterial-type flagellum organization
AM681_RS15595	COG1157	protein secretion by the type III secretion system
AM681_RS15600	COG2882	bacterial-type flagellum organization
AM681_RS15605	COG3144	bacterial-type flagellum assembly
AM681_RS15660	COG1256	bacterial-type flagellum assembly
AM681_RS15700	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AM681_RS15705	COG1558	bacterial-type flagellum-dependent cell motility
AM681_RS15710	COG1815	bacterial-type flagellum-dependent cell motility
AM681_RS15720	COG2747	anti-sigma28 factor FlgM
AM681_RS15725	COG3418	PFAM FlgN family protein
AM681_RS15740	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AM681_RS15750	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM681_RS15755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM681_RS15760	COG1487	ribonuclease activity
AM681_RS15770	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AM681_RS15775	COG0745	RESPONSE REGULATOR receiver
AM681_RS15785	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AM681_RS15790	COG0840	transmembrane signaling receptor activity
AM681_RS15795	COG0840	transmembrane signaling receptor activity
AM681_RS15800	COG0835	chemotaxis
AM681_RS15805	COG2198	Histidine kinase
AM681_RS15805	COG0643	Histidine kinase
AM681_RS15835	COG0589	response to stress
AM681_RS15840	COG2130	NADP-dependent
AM681_RS15845	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AM681_RS16035	COG3039	Transposase
AM681_RS16045	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM681_RS16050	COG3483	tryptophan 2,3-dioxygenase activity
AM681_RS16100	COG2814	Major facilitator Superfamily
AM681_RS16210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM681_RS16220	COG3781	membrane
AM681_RS16225	COG2837	iron assimilation
AM681_RS16235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM681_RS16245	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AM681_RS16270	COG1285	pathogenesis
AM681_RS16280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM681_RS16290	COG0076	glutamate decarboxylase activity
AM681_RS16435	COG3228	Belongs to the MtfA family
AM681_RS16445	COG0582	viral genome integration into host DNA
AM681_RS16580	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM681_RS16615	COG3311	Transcriptional regulator
AM681_RS16625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM681_RS16630	COG4977	sequence-specific DNA binding
AM681_RS16640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM681_RS16645	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM681_RS16650	COG1116	anion transmembrane transporter activity
AM681_RS16655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM681_RS16660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM681_RS16675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM681_RS16690	COG3238	Protein conserved in bacteria
AM681_RS16695	COG1247	-acetyltransferase
AM681_RS16715	COG0583	DNA-binding transcription factor activity
AM681_RS16725	COG0859	PFAM glycosyl transferase family 9
AM681_RS16745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM681_RS16765	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS16770	COG1169	isochorismate synthase
AM681_RS16785	COG0471	metal ion transport
AM681_RS16790	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AM681_RS16800	COG3051	citrate lyase alpha subunit
AM681_RS16805	COG2301	Belongs to the HpcH HpaI aldolase family
AM681_RS16810	COG3052	prosthetic group binding
AM681_RS16815	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AM681_RS16820	COG3250	beta-galactosidase activity
AM681_RS16855	COG1121	(ABC) transporter
AM681_RS16905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM681_RS16930	COG2197	response regulator
AM681_RS16945	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS16950	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AM681_RS16970	COG2070	2-Nitropropane dioxygenase
AM681_RS16990	COG2271	Major facilitator Superfamily
AM681_RS17020	COG0411	ABC transporter
AM681_RS17075	COG0583	DNA-binding transcription factor activity
AM681_RS17135	COG1609	Transcriptional regulator
AM681_RS17145	COG3623	hexulose-6-phosphate isomerase
AM681_RS17150	COG1070	Carbohydrate kinase
AM681_RS17155	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM681_RS17165	COG1879	ABC-type sugar transport system periplasmic component
AM681_RS17170	COG1063	alcohol dehydrogenase
AM681_RS17180	COG1473	amidohydrolase
AM681_RS17185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM681_RS17190	COG2926	Belongs to the UPF0265 family
AM681_RS17195	COG1289	transmembrane transporter activity
AM681_RS17200	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM681_RS17225	COG2925	Exonuclease
AM681_RS17230	COG0531	amino acid
AM681_RS17240	COG0174	glutamine synthetase
AM681_RS17245	COG1917	Cupin 2, conserved barrel domain protein
AM681_RS17245	COG1396	sequence-specific DNA binding
AM681_RS17250	COG1129	ABC transporter
AM681_RS17255	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM681_RS17260	COG4771	TonB-dependent receptor
AM681_RS17275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM681_RS17285	COG0833	amino acid
AM681_RS17290	COG0583	DNA-binding transcription factor activity
AM681_RS17300	COG2855	membrane
AM681_RS17305	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AM681_RS17315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM681_RS17315	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM681_RS17315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM681_RS17320	COG1105	Belongs to the carbohydrate kinase PfkB family
AM681_RS17325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS17325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS17330	COG0494	nUDIX hydrolase
AM681_RS17335	COG3005	denitrification pathway
AM681_RS17340	COG0243	molybdopterin cofactor binding
AM681_RS17360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM681_RS17365	COG1312	Catalyzes the dehydration of D-mannonate
AM681_RS17370	COG0246	Mannitol dehydrogenase
AM681_RS17380	COG0523	cobalamin synthesis protein
AM681_RS17385	COG0671	phosphoesterase, PA-phosphatase related
AM681_RS17395	COG0791	NLP P60 protein
AM681_RS17400	COG2200	EAL domain
AM681_RS17405	COG4166	transmembrane transport
AM681_RS17410	COG4174	ABC transporter (Permease)
AM681_RS17415	COG4239	(ABC) transporter, permease
AM681_RS17420	COG4172	Belongs to the ABC transporter superfamily
AM681_RS17430	COG2814	Major facilitator Superfamily
AM681_RS17435	COG1187	pseudouridine synthase activity
AM681_RS17440	COG1061	Type III restriction enzyme res subunit
AM681_RS17445	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AM681_RS17450	COG3081	Nucleoid-associated protein
AM681_RS17455	COG3082	Protein of unknown function (DUF1414)
AM681_RS17460	COG3083	sulfuric ester hydrolase activity
AM681_RS17505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM681_RS17540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM681_RS17555	COG0346	lactoylglutathione lyase activity
AM681_RS17580	COG2223	nitrite transmembrane transporter activity
AM681_RS17585	COG0642	Histidine kinase
AM681_RS17585	COG2198	Histidine kinase
AM681_RS17590	COG2197	response regulator
AM681_RS17595	COG0784	Response regulator, receiver
AM681_RS17595	COG2205	protein histidine kinase activity
AM681_RS17605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM681_RS17610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM681_RS17620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM681_RS17650	COG0814	amino acid
AM681_RS17675	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM681_RS17680	COG0596	Alpha beta hydrolase
AM681_RS17685	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AM681_RS17690	COG4575	ribosome binding
AM681_RS17695	COG1063	alcohol dehydrogenase
AM681_RS17700	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS17705	COG1609	Transcriptional regulator
AM681_RS17720	COG0583	DNA-binding transcription factor activity
AM681_RS17725	COG1007	ATP synthesis coupled electron transport
AM681_RS17730	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM681_RS17735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM681_RS17740	COG0713	ATP synthesis coupled electron transport
AM681_RS17745	COG0839	Belongs to the complex I subunit 6 family
AM681_RS17755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM681_RS17760	COG1034	ATP synthesis coupled electron transport
AM681_RS17775	COG0649	NAD binding
AM681_RS17775	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM681_RS17780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM681_RS17785	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM681_RS17790	COG0583	DNA-binding transcription factor activity
AM681_RS17795	COG0436	Aminotransferase
AM681_RS17800	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM681_RS17805	COG0471	metal ion transport
AM681_RS17805	COG0490	domain, Protein
AM681_RS17810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM681_RS17815	COG3013	Belongs to the UPF0304 family
AM681_RS17820	COG3092	negative regulation of chromosome organization
AM681_RS17825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM681_RS17830	COG0280	phosphate acetyltransferase
AM681_RS17830	COG0857	belongs to the CobB CobQ family
AM681_RS17845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM681_RS17850	COG3959	Transketolase, thiamine diphosphate binding domain
AM681_RS17855	COG3037	sugar-specific permease SgaT UlaA
AM681_RS17865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS17870	COG1609	Transcriptional regulator
AM681_RS17875	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM681_RS17880	COG0622	Phosphoesterase
AM681_RS17885	COG0625	glutathione transferase activity
AM681_RS17890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM681_RS17895	COG1090	epimerase
AM681_RS17900	COG4598	ABC transporter
AM681_RS17910	COG4215	(ABC) transporter
AM681_RS17915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM681_RS17920	COG0163	prenyltransferase activity
AM681_RS17925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM681_RS17930	COG1286	toxin biosynthetic process
AM681_RS17935	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM681_RS17940	COG0285	dihydrofolate synthase activity
AM681_RS17945	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM681_RS17950	COG0586	Pfam SNARE associated Golgi protein
AM681_RS17960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM681_RS17965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM681_RS17975	COG0697	spore germination
AM681_RS17980	COG0642	Histidine kinase
AM681_RS18020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM681_RS18025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM681_RS18065	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM681_RS18070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM681_RS18085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM681_RS18090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM681_RS18090	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM681_RS18100	COG3101	peptidyl-lysine hydroxylation
AM681_RS18105	COG0730	response to heat
AM681_RS18110	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AM681_RS18115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM681_RS18120	COG2890	protein-(glutamine-N5) methyltransferase activity
AM681_RS18125	COG2840	Smr protein MutS2
AM681_RS18130	COG2062	phosphohistidine phosphatase, SixA
AM681_RS18135	COG1024	Enoyl-CoA hydratase
AM681_RS18135	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM681_RS18140	COG0183	Belongs to the thiolase family
AM681_RS18145	COG3691	Protein conserved in bacteria
AM681_RS18160	COG3088	subunit of a heme lyase
AM681_RS18160	COG4235	cytochrome complex assembly
AM681_RS18165	COG4235	cytochrome complex assembly
AM681_RS18165	COG3088	subunit of a heme lyase
AM681_RS18170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM681_RS18175	COG1138	Cytochrome C-type biogenesis protein
AM681_RS18180	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AM681_RS18185	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM681_RS18190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM681_RS18195	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM681_RS18205	COG2116	formate transmembrane transporter activity
AM681_RS18220	COG3708	Transcriptional regulator
AM681_RS18220	COG2207	Transcriptional regulator
AM681_RS18235	COG2197	response regulator
AM681_RS18255	COG0583	DNA-binding transcription factor activity
AM681_RS18265	COG0697	spore germination
AM681_RS18280	COG2951	lytic endotransglycosylase activity
AM681_RS18295	COG1215	transferase activity, transferring glycosyl groups
AM681_RS18300	COG0726	polysaccharide deacetylase
AM681_RS18300	COG1649	PFAM Uncharacterised BCR, COG1649
AM681_RS18305	COG0457	Tetratricopeptide repeat
AM681_RS18310	COG1598	PFAM Uncharacterised protein family UPF0150
AM681_RS18330	COG3038	cytochrome b561
AM681_RS18335	COG0436	Aminotransferase
AM681_RS18350	COG3275	phosphorelay sensor kinase activity
AM681_RS18355	COG3279	Response regulator of the LytR AlgR family
AM681_RS18365	COG2223	nitrite transmembrane transporter activity
AM681_RS18380	COG1794	racemase activity, acting on amino acids and derivatives
AM681_RS18395	COG3961	Belongs to the TPP enzyme family
AM681_RS18400	COG0667	Aldo Keto reductase
AM681_RS18410	COG1914	H( )-stimulated, divalent metal cation uptake system
AM681_RS18415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM681_RS18435	COG2116	formate transmembrane transporter activity
AM681_RS18440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM681_RS18465	COG4592	Periplasmic binding protein
AM681_RS18470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM681_RS18475	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM681_RS18480	COG1120	ATPase activity
AM681_RS18490	COG0747	negative chemotaxis
AM681_RS18510	COG4302	ethanolamine ammonia-lyase activity
AM681_RS18515	COG4303	Ethanolamine ammonia lyase large subunit
AM681_RS18530	COG0583	DNA-binding transcription factor activity
AM681_RS18535	COG0385	Bile acid
AM681_RS18545	COG3530	Putative quorum-sensing-regulated virulence factor
AM681_RS18550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM681_RS18555	COG3115	cell septum assembly
AM681_RS18560	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AM681_RS18570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS18575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM681_RS18585	COG2205	protein histidine kinase activity
AM681_RS18590	COG0745	RESPONSE REGULATOR receiver
AM681_RS18605	COG4208	sulfate ABC transporter
AM681_RS18610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM681_RS18620	COG2837	iron assimilation
AM681_RS18635	COG3111	PFAM Bacterial OB fold (BOF) protein
AM681_RS18640	COG0456	acetyltransferase
AM681_RS18645	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM681_RS18650	COG0408	coproporphyrinogen oxidase activity
AM681_RS18665	COG1770	oligopeptidase
AM681_RS18680	COG0833	amino acid
AM681_RS18685	COG2040	homocysteine
AM681_RS18700	COG0281	malic enzyme
AM681_RS18700	COG0280	phosphate acetyltransferase
AM681_RS18725	COG0583	DNA-binding transcription factor activity
AM681_RS18730	COG3397	chitin binding
AM681_RS18740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM681_RS18745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM681_RS18750	COG0494	nUDIX hydrolase
AM681_RS18755	COG3850	Histidine kinase
AM681_RS18760	COG2197	response regulator
AM681_RS18770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM681_RS18790	COG0454	-acetyltransferase
AM681_RS18800	COG1393	Belongs to the ArsC family
AM681_RS18805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM681_RS18810	COG1876	peptidase activity
AM681_RS18820	COG0400	carboxylic ester hydrolase activity
AM681_RS18830	COG2321	neutral zinc metallopeptidase
AM681_RS18835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM681_RS18840	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM681_RS18845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM681_RS18850	COG2716	regulation of RNA biosynthetic process
AM681_RS18855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM681_RS18860	COG0628	permease
AM681_RS18910	COG4783	chaperone-mediated protein folding
AM681_RS18915	COG1393	Belongs to the ArsC family
AM681_RS18920	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM681_RS18930	COG3039	Transposase
AM681_RS18935	COG2261	transglycosylase associated protein
AM681_RS18940	COG2233	PERMEase
AM681_RS18945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM681_RS18950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM681_RS18955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM681_RS18960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM681_RS18975	COG0573	inorganic phosphate transmembrane transporter activity
AM681_RS18980	COG0573	inorganic phosphate transmembrane transporter activity
AM681_RS18985	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM681_RS19000	COG2239	Acts as a magnesium transporter
AM681_RS19005	COG3447	MASE1 domain protein
AM681_RS19005	COG5001	Diguanylate cyclase
AM681_RS19005	COG5002	protein histidine kinase activity
AM681_RS19020	COG0443	Heat shock 70 kDa protein
AM681_RS19035	COG0667	Aldo Keto reductase
AM681_RS19040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS19045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM681_RS19050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM681_RS19055	COG2814	Major facilitator Superfamily
AM681_RS19060	COG2205	protein histidine kinase activity
AM681_RS19065	COG0745	RESPONSE REGULATOR receiver
AM681_RS19080	COG3422	double-strand break repair
AM681_RS19085	COG0826	peptidase U32
AM681_RS19095	COG1597	lipid kinase activity
AM681_RS19105	COG1830	Aldolase
AM681_RS19110	COG3730	PTS system glucitol sorbitol-specific
AM681_RS19125	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS19130	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS19135	COG1349	DNA-binding transcription factor activity
AM681_RS19150	COG0351	phosphomethylpyrimidine kinase
AM681_RS19155	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AM681_RS19170	COG2814	Major facilitator Superfamily
AM681_RS19190	COG1187	pseudouridine synthase activity
AM681_RS19220	COG2198	Histidine kinase
AM681_RS19220	COG0784	Response regulator, receiver
AM681_RS19220	COG2205	protein histidine kinase activity
AM681_RS19235	COG0519	Catalyzes the synthesis of GMP from XMP
AM681_RS19235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM681_RS19240	COG0516	GMP reductase activity
AM681_RS19240	COG0517	IMP dehydrogenase activity
AM681_RS19250	COG1570	exodeoxyribonuclease VII activity
AM681_RS19260	COG2271	Major facilitator Superfamily
AM681_RS19265	COG1609	Transcriptional regulator
AM681_RS19280	COG1645	bacterial-type flagellum-dependent swarming motility
AM681_RS19290	COG1160	GTP binding
AM681_RS19295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM681_RS19300	COG2976	Protein conserved in bacteria
AM681_RS19305	COG0124	histidyl-tRNA synthetase
AM681_RS19310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM681_RS19315	COG1426	Protein conserved in bacteria
AM681_RS19325	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM681_RS19330	COG0105	UTP biosynthetic process
AM681_RS19340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM681_RS19350	COG2975	iron-sulfur cluster assembly
AM681_RS19355	COG0633	Ferredoxin
AM681_RS19360	COG0443	Heat shock 70 kDa protein
AM681_RS19365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM681_RS19370	COG0316	Belongs to the HesB IscA family
AM681_RS19375	COG0822	iron-sulfur transferase activity
AM681_RS19380	COG1104	cysteine desulfurase activity
AM681_RS19385	COG1959	2 iron, 2 sulfur cluster binding
AM681_RS19400	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM681_RS19405	COG3683	transport system, periplasmic component
AM681_RS19410	COG3711	transcriptional antiterminator
AM681_RS19415	COG2814	Major facilitator Superfamily
AM681_RS19420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM681_RS19430	COG1017	nitric oxide dioxygenase activity
AM681_RS19430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM681_RS19440	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AM681_RS19445	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS19450	COG1177	transmembrane transport
AM681_RS19455	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM681_RS19460	COG3842	ATPase activity
AM681_RS19465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM681_RS19475	COG0583	DNA-binding transcription factor activity
AM681_RS19485	COG0347	Belongs to the P(II) protein family
AM681_RS19490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM681_RS19490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM681_RS19495	COG2204	response regulator
AM681_RS19500	COG3170	Tfp pilus assembly protein FimV
AM681_RS19505	COG2205	protein histidine kinase activity
AM681_RS19515	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM681_RS19530	COG0560	Phosphoserine phosphatase
AM681_RS19535	COG1263	PTS System
AM681_RS19535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM681_RS19540	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM681_RS19545	COG1737	Transcriptional regulator
AM681_RS19550	COG2194	sulfuric ester hydrolase activity
AM681_RS19555	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM681_RS19560	COG0736	holo-[acyl-carrier-protein] synthase activity
AM681_RS19565	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM681_RS19570	COG1381	Involved in DNA repair and RecF pathway recombination
AM681_RS19575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM681_RS19580	COG0571	ribonuclease III activity
AM681_RS19590	COG0481	GTPase activity
AM681_RS19600	COG3086	response to oxidative stress
AM681_RS19605	COG3026	antisigma factor binding
AM681_RS19620	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM681_RS19625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM681_RS19630	COG0513	Belongs to the DEAD box helicase family
AM681_RS19650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM681_RS19655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM681_RS19660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM681_RS19665	COG0497	DNA recombination
AM681_RS19670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM681_RS19675	COG2914	Belongs to the UPF0125 (RnfH) family
AM681_RS19680	COG2867	negative regulation of translational initiation
AM681_RS19685	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM681_RS19705	COG3182	Iron-regulated membrane protein
AM681_RS19745	COG2388	GCN5-related N-acetyl-transferase
AM681_RS19750	COG3592	Divergent 4Fe-4S mono-cluster
AM681_RS19755	COG2259	Doxx family
AM681_RS19760	COG2840	Smr protein MutS2
AM681_RS19780	COG0477	Major facilitator Superfamily
AM681_RS19790	COG0477	Major facilitator Superfamily
AM681_RS19805	COG4575	ribosome binding
AM681_RS19815	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM681_RS19820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM681_RS19825	COG1780	Probably involved in ribonucleotide reductase function
AM681_RS19845	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS19855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM681_RS19860	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM681_RS19865	COG3493	citrate carrier protein
AM681_RS19885	COG4176	ABC-type proline glycine betaine transport system permease component
AM681_RS19890	COG2113	Glycine betaine
AM681_RS19895	COG0583	DNA-binding transcription factor activity
AM681_RS19900	COG2814	Major facilitator Superfamily
AM681_RS19905	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM681_RS19915	COG1846	Transcriptional regulator
AM681_RS19925	COG1566	PFAM secretion protein HlyD family protein
AM681_RS19930	COG2814	Major facilitator Superfamily
AM681_RS19935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM681_RS19940	COG3118	belongs to the thioredoxin family
AM681_RS19945	COG3148	PFAM DTW domain containing protein
AM681_RS19950	COG1042	CoA-binding domain protein
AM681_RS19950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM681_RS19950	COG0045	succinate-CoA ligase (ADP-forming) activity
AM681_RS19955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM681_RS19960	COG0477	Major facilitator Superfamily
AM681_RS19990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM681_RS20000	COG2011	ABC-type metal ion transport system permease component
AM681_RS20015	COG1720	tRNA m6t6A37 methyltransferase activity
AM681_RS20020	COG0442	prolyl-tRNA aminoacylation
AM681_RS20030	COG3015	lipoprotein NlpE involved in copper resistance
AM681_RS20035	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM681_RS20050	COG4568	rho-dependent transcription termination
AM681_RS20060	COG0037	tRNA processing
AM681_RS20065	COG3104	oligopeptide transport
AM681_RS20075	COG0531	amino acid
AM681_RS20080	COG3710	Transcriptional regulator
AM681_RS20085	COG0346	lactoylglutathione lyase activity
AM681_RS20090	COG1982	Orn Lys Arg decarboxylase major
AM681_RS20095	COG0825	malonyl-CoA metabolic process
AM681_RS20100	COG0587	DNA-directed DNA polymerase activity
AM681_RS20105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM681_RS20110	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM681_RS20115	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM681_RS20120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM681_RS20125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM681_RS20130	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM681_RS20135	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM681_RS20140	COG0750	zinc metalloprotease
AM681_RS20145	COG0575	Belongs to the CDS family
AM681_RS20150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM681_RS20155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM681_RS20160	COG0233	cytoplasmic translational termination
AM681_RS20165	COG0528	UMP kinase activity
AM681_RS20175	COG0052	Belongs to the universal ribosomal protein uS2 family
AM681_RS20185	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM681_RS20205	COG0564	pseudouridine synthase activity
AM681_RS20210	COG4953	penicillin-binding protein 1C
AM681_RS20215	COG2373	Large extracellular alpha-helical protein
AM681_RS20220	COG3098	single-species biofilm formation
AM681_RS20225	COG2814	Major facilitator Superfamily
AM681_RS20240	COG1611	Belongs to the LOG family
AM681_RS20245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM681_RS20250	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AM681_RS20255	COG2363	Small membrane protein
AM681_RS20260	COG0583	DNA-binding transcription factor activity
AM681_RS20270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM681_RS20275	COG2166	iron-sulfur cluster assembly
AM681_RS20280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM681_RS20285	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM681_RS20310	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM681_RS20315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM681_RS20315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM681_RS20320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM681_RS20325	COG1074	ATP-dependent DNA helicase activity
AM681_RS20330	COG1025	Belongs to the peptidase M16 family
AM681_RS20335	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM681_RS20355	COG2165	general secretion pathway protein
AM681_RS20360	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM681_RS20365	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM681_RS20375	COG0494	nUDIX hydrolase
AM681_RS20385	COG3066	DNA modification
AM681_RS20390	COG0861	Integral membrane protein TerC family
AM681_RS20400	COG0667	Aldo Keto reductase
AM681_RS20405	COG0477	Major facilitator Superfamily
AM681_RS20410	COG0204	Acyl-transferase
AM681_RS20410	COG0318	PFAM AMP-dependent synthetase and ligase
AM681_RS20430	COG1609	Transcriptional regulator
AM681_RS20450	COG0583	DNA-binding transcription factor activity
AM681_RS20455	COG0583	DNA-binding transcription factor activity
AM681_RS20475	COG4178	(ABC) transporter
AM681_RS20485	COG3716	PTS system mannose fructose sorbose family IID component
AM681_RS20490	COG3715	PTS system
AM681_RS20495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM681_RS20505	COG1349	DNA-binding transcription factor activity
AM681_RS20510	COG2807	transmembrane transport
AM681_RS20520	COG4615	Cyclic peptide transporter
AM681_RS20525	COG0583	DNA-binding transcription factor activity
AM681_RS20530	COG1620	l-lactate permease
AM681_RS20535	COG1304	FMN binding
AM681_RS20545	COG2814	Major facilitator Superfamily
AM681_RS20555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM681_RS20560	COG1309	transcriptional regulator
AM681_RS20565	COG5265	(ABC) transporter
AM681_RS20570	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM681_RS20575	COG4942	peptidase
AM681_RS20580	COG3247	response to pH
AM681_RS20595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM681_RS20605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM681_RS20615	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM681_RS20625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM681_RS20630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM681_RS20635	COG4974	Belongs to the 'phage' integrase family
AM681_RS20640	COG0716	FMN binding
AM681_RS20650	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM681_RS20655	COG0354	folic acid binding
AM681_RS20665	COG1272	protein, Hemolysin III
AM681_RS20675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM681_RS20680	COG1940	carbohydrate kinase activity
AM681_RS20685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM681_RS20695	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM681_RS20700	COG1129	ABC transporter
AM681_RS20710	COG1349	DNA-binding transcription factor activity
AM681_RS20725	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS20755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM681_RS20755	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM681_RS20760	COG0509	glycine decarboxylation via glycine cleavage system
AM681_RS20765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM681_RS20770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM681_RS20775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM681_RS20780	COG0006	proline dipeptidase activity
AM681_RS20785	COG3079	Belongs to the UPF0149 family
AM681_RS20790	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AM681_RS20800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM681_RS20805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM681_RS20815	COG0583	DNA-binding transcription factor activity
AM681_RS20825	COG1279	arginine transmembrane transporter activity
AM681_RS20830	COG0564	pseudouridine synthase activity
AM681_RS20835	COG3122	Protein conserved in bacteria
AM681_RS20850	COG2271	Major facilitator Superfamily
AM681_RS20875	COG0191	fructose-bisphosphate aldolase activity
AM681_RS20880	COG0126	phosphoglycerate kinase activity
AM681_RS20885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM681_RS20890	COG0583	DNA-binding transcription factor activity
AM681_RS20895	COG0473	3-isopropylmalate dehydrogenase activity
AM681_RS20900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM681_RS20905	COG4638	Rieske (2fe-2S)
AM681_RS20915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM681_RS20920	COG3842	ATPase activity
AM681_RS20925	COG1175	transmembrane transport
AM681_RS20940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM681_RS20950	COG1114	Component of the transport system for branched-chain amino acids
AM681_RS20955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM681_RS20960	COG0501	Belongs to the peptidase M48B family
AM681_RS20975	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AM681_RS20980	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS20985	COG2267	carboxylic ester hydrolase activity
AM681_RS21010	COG1414	Transcriptional regulator
AM681_RS21015	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS21030	COG2146	nitrite reductase [NAD(P)H] activity
AM681_RS21035	COG2271	Major facilitator Superfamily
AM681_RS21050	COG0010	Belongs to the arginase family
AM681_RS21080	COG3121	Chaperone
AM681_RS21090	COG1166	arginine decarboxylase activity
AM681_RS21105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM681_RS21120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM681_RS21125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM681_RS21130	COG1120	ATPase activity
AM681_RS21135	COG4774	siderophore transport
AM681_RS21140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM681_RS21145	COG1643	Atp-dependent helicase
AM681_RS21150	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM681_RS21155	COG1489	DNA binding
AM681_RS21170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM681_RS21175	COG0617	tRNA 3'-terminal CCA addition
AM681_RS21180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM681_RS21185	COG0642	Histidine kinase
AM681_RS21195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM681_RS21200	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM681_RS21205	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM681_RS21210	COG0726	polysaccharide deacetylase
AM681_RS21215	COG0842	Transport permease protein
AM681_RS21220	COG1131	(ABC) transporter
AM681_RS21225	COG0288	reversible hydration of carbon dioxide
AM681_RS21245	COG2132	Multicopper oxidase
AM681_RS21255	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AM681_RS21260	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AM681_RS21265	COG3112	Uncharacterised protein family (UPF0231)
AM681_RS21280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM681_RS21285	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM681_RS21290	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM681_RS21295	COG2186	Transcriptional regulator
AM681_RS21300	COG1113	amino acid transport
AM681_RS21310	COG2010	Cytochrome c
AM681_RS21310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM681_RS21320	COG2010	Cytochrome c
AM681_RS21320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM681_RS21330	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM681_RS21335	COG2207	Transcriptional regulator
AM681_RS21335	COG3708	Transcriptional regulator
AM681_RS21345	COG3091	SprT-like family
AM681_RS21350	COG2356	endonuclease I
AM681_RS21355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM681_RS21360	COG0189	ligase activity
AM681_RS21365	COG1678	Uncharacterized ACR, COG1678
AM681_RS21370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM681_RS21375	COG2805	Type II/IV secretion system protein
AM681_RS21380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM681_RS21385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM681_RS21390	COG0762	integral membrane protein
AM681_RS21395	COG1872	DUF167
AM681_RS21405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM681_RS21425	COG2066	Belongs to the glutaminase family
AM681_RS21430	COG3171	Protein conserved in bacteria
AM681_RS21435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM681_RS21445	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AM681_RS21450	COG0741	lytic transglycosylase activity
AM681_RS21455	COG1982	Orn Lys Arg decarboxylase major
AM681_RS21485	COG3539	Fimbrial protein
AM681_RS21495	COG3121	Chaperone
AM681_RS21505	COG3188	usher protein
AM681_RS21515	COG3188	usher protein
AM681_RS21555	COG2819	hydrolase of the alpha beta superfamily
AM681_RS21560	COG0454	-acetyltransferase
AM681_RS21585	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM681_RS21585	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM681_RS21620	COG0848	biopolymer transport protein
AM681_RS21635	COG0586	Pfam SNARE associated Golgi protein
AM681_RS21640	COG0583	DNA-binding transcription factor activity
AM681_RS21645	COG0604	alcohol dehydrogenase
AM681_RS21645	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS21645	COG3321	synthase
AM681_RS21650	COG2207	Transcriptional regulator
AM681_RS21655	COG1979	alcohol dehydrogenase
AM681_RS21660	COG0656	L-ascorbic acid biosynthetic process
AM681_RS21665	COG0741	lytic transglycosylase activity
AM681_RS21715	COG3436	PFAM IS66 Orf2 family protein
AM681_RS21735	COG2205	protein histidine kinase activity
AM681_RS21740	COG0745	RESPONSE REGULATOR receiver
AM681_RS21745	COG1276	copper resistance
AM681_RS21750	COG2372	response to copper ion
AM681_RS21755	COG3667	copper resistance
AM681_RS21770	COG2132	Multicopper oxidase
AM681_RS21780	COG0739	heme binding
AM681_RS21800	COG3436	PFAM IS66 Orf2 family protein
AM681_RS21805	COG2433	Pfam Transposase IS66
AM681_RS21830	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS21890	COG1595	DNA-templated transcription, initiation
AM681_RS21895	COG3712	iron ion homeostasis
AM681_RS21900	COG4772	TonB-dependent receptor
AM681_RS21905	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AM681_RS21910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM681_RS21915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM681_RS21920	COG1120	ATPase activity
AM681_RS21925	COG3436	PFAM IS66 Orf2 family protein
AM681_RS21955	COG0640	Transcriptional regulator
AM681_RS21960	COG0431	NADPH-dependent FMN reductase
AM681_RS21995	COG1609	Transcriptional regulator
AM681_RS22005	COG2223	nitrite transmembrane transporter activity
AM681_RS22010	COG0110	maltose O-acetyltransferase activity
AM681_RS22060	COG1234	tRNA 3'-trailer cleavage
AM681_RS22080	COG0583	DNA-binding transcription factor activity
AM681_RS22085	COG1902	pentaerythritol trinitrate reductase activity
AM681_RS22090	COG0640	Transcriptional regulator
AM681_RS22140	COG2186	Transcriptional regulator
AM681_RS22150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM681_RS22155	COG2211	Major facilitator Superfamily
AM681_RS22160	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM681_RS22165	COG0583	DNA-binding transcription factor activity
AM681_RS22170	COG2132	Multicopper oxidase
AM681_RS22175	COG0204	Acyl-transferase
AM681_RS22185	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM681_RS22190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM681_RS22195	COG0583	DNA-binding transcription factor activity
AM681_RS22200	COG0187	DNA topoisomerase II activity
AM681_RS22205	COG3150	esterase
AM681_RS22210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM681_RS22215	COG3151	Protein conserved in bacteria
AM681_RS22220	COG0494	nUDIX hydrolase
AM681_RS22225	COG1538	Outer membrane efflux protein
AM681_RS22235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS22235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM681_RS22235	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AM681_RS22240	COG1461	Dihydroxyacetone kinase
AM681_RS22245	COG2376	Dihydroxyacetone kinase
AM681_RS22255	COG5463	Belongs to the UPF0441 family
AM681_RS22260	COG0754	glutathionylspermidine amidase activity
AM681_RS22265	COG3384	dioxygenase
AM681_RS22275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM681_RS22285	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AM681_RS22285	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AM681_RS22290	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM681_RS22295	COG3025	triphosphatase activity
AM681_RS22300	COG4991	sh3 domain protein
AM681_RS22305	COG0617	tRNA 3'-terminal CCA addition
AM681_RS22310	COG1968	undecaprenyl-diphosphatase activity
AM681_RS22315	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM681_RS22320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AM681_RS22325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM681_RS22330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM681_RS22335	COG0358	DNA primase activity
AM681_RS22380	COG0625	glutathione transferase activity
AM681_RS22390	COG1012	belongs to the aldehyde dehydrogenase family
AM681_RS22395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM681_RS22405	COG0488	(ABC) transporter
AM681_RS22415	COG1902	pentaerythritol trinitrate reductase activity
AM681_RS22415	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM681_RS22420	COG2813	Specifically methylates the guanine in position
AM681_RS22425	COG1451	nucleotide metabolic process
AM681_RS22430	COG0673	inositol 2-dehydrogenase activity
AM681_RS22435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM681_RS22435	COG0519	Catalyzes the synthesis of GMP from XMP
AM681_RS22440	COG0861	Integral membrane protein TerC family
AM681_RS22445	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AM681_RS22450	COG2721	sulfolactate sulfo-lyase activity
AM681_RS22455	COG1904	glucuronate isomerase
AM681_RS22460	COG2271	Major facilitator Superfamily
AM681_RS22475	COG0586	Pfam SNARE associated Golgi protein
AM681_RS22480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM681_RS22490	COG4575	ribosome binding
AM681_RS22495	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM681_RS22505	COG2259	Doxx family
AM681_RS22510	COG0435	Glutathione S-transferase
AM681_RS22515	COG0583	DNA-binding transcription factor activity
AM681_RS22520	COG1741	Belongs to the pirin family
AM681_RS22530	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM681_RS22535	COG3107	peptidoglycan biosynthetic process
AM681_RS22540	COG0792	nuclease activity
AM681_RS22545	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM681_RS22550	COG2823	Periplasmic or secreted lipoprotein
AM681_RS22560	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM681_RS22565	COG5002	protein histidine kinase activity
AM681_RS22565	COG2198	Histidine kinase
AM681_RS22565	COG0784	Response regulator, receiver
AM681_RS22575	COG1242	4 iron, 4 sulfur cluster binding
AM681_RS22585	COG0070	glutamate synthase
AM681_RS22585	COG0069	glutamate synthase activity
AM681_RS22585	COG0067	glutamate synthase
AM681_RS22590	COG0493	'glutamate synthase
AM681_RS22600	COG2969	positive regulation of protein catabolic process
AM681_RS22605	COG0625	glutathione transferase activity
AM681_RS22610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM681_RS22615	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM681_RS22620	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM681_RS22625	COG3105	Protein conserved in bacteria
AM681_RS22630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM681_RS22635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM681_RS22640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM681_RS22645	COG5007	Belongs to the BolA IbaG family
AM681_RS22650	COG3113	response to antibiotic
AM681_RS22655	COG2854	intermembrane phospholipid transfer
AM681_RS22660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM681_RS22665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM681_RS22670	COG1127	ABC transporter
AM681_RS22675	COG0530	calcium, potassium:sodium antiporter activity
AM681_RS22680	COG0517	IMP dehydrogenase activity
AM681_RS22680	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM681_RS22685	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM681_RS22690	COG3117	lipopolysaccharide transmembrane transporter activity
AM681_RS22695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM681_RS22700	COG1137	ATPase activity
AM681_RS22705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM681_RS22720	COG1660	Displays ATPase and GTPase activities
AM681_RS22725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS22730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM681_RS22730	COG3711	transcriptional antiterminator
AM681_RS22750	COG3964	amidohydrolase
AM681_RS22780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM681_RS22790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM681_RS22800	COG2207	Transcriptional regulator
AM681_RS22805	COG3783	Cytochrome b(562)
AM681_RS22810	COG0312	modulator of DNA gyrase
AM681_RS22815	COG3028	Belongs to the UPF0307 family
AM681_RS22820	COG2732	(Barnase) inhibitor
AM681_RS22830	COG1289	transmembrane transporter activity
AM681_RS22835	COG1566	PFAM secretion protein HlyD family protein
AM681_RS22845	COG0583	DNA-binding transcription factor activity
AM681_RS22870	COG2134	cdp-diacylglycerol pyrophosphatase
AM681_RS22875	COG0312	modulator of DNA gyrase
AM681_RS22880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM681_RS22885	COG3164	Protein of unknown function
AM681_RS22890	COG1530	ribonuclease E activity
AM681_RS22895	COG0424	maF-like protein
AM681_RS22900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM681_RS22905	COG1792	Involved in formation and maintenance of cell shape
AM681_RS22910	COG1077	Cell shape determining protein MreB Mrl
AM681_RS22915	COG2200	EAL domain
AM681_RS22915	COG2199	diguanylate cyclase activity
AM681_RS22920	COG0604	alcohol dehydrogenase
AM681_RS22925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM681_RS22930	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AM681_RS22935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM681_RS22940	COG0511	ligase activity, forming carbon-carbon bonds
AM681_RS22945	COG0439	Biotin carboxylase
AM681_RS22950	COG3924	membrane
AM681_RS22955	COG4145	pantothenate transmembrane transporter activity
AM681_RS22960	COG2264	protein methyltransferase activity
AM681_RS22985	COG1560	Kdo2-lipid A biosynthetic process
AM681_RS22995	COG0504	CTP synthase activity
AM681_RS23015	COG1380	Effector of murein hydrolase LrgA
AM681_RS23020	COG0583	DNA-binding transcription factor activity
AM681_RS23025	COG0025	NhaP-type Na H and K H
AM681_RS23030	COG2252	PERMEase
AM681_RS23040	COG0625	glutathione transferase activity
AM681_RS23055	COG1028	Short-chain dehydrogenase reductase Sdr
AM681_RS23120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM681_RS23125	COG1064	alcohol dehydrogenase
AM681_RS23130	COG0110	maltose O-acetyltransferase activity
AM681_RS23135	COG2315	Protein conserved in bacteria
AM681_RS23140	COG0432	Pfam Uncharacterised protein family UPF0047
AM681_RS23145	COG1448	Aminotransferase
AM681_RS23150	COG1522	sequence-specific DNA binding
AM681_RS23170	COG0604	alcohol dehydrogenase
AM681_RS23180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM681_RS23190	COG0735	belongs to the Fur family
AM681_RS23195	COG3237	CsbD-like
AM681_RS23200	COG0534	Mate efflux family protein
AM681_RS23205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM681_RS23210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM681_RS23215	COG2937	Belongs to the GPAT DAPAT family
AM681_RS23220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM681_RS23225	COG3161	chorismate lyase activity
AM681_RS23230	COG0477	Major facilitator Superfamily
AM681_RS23235	COG1609	Transcriptional regulator
AM681_RS23250	COG4580	involved in the transport of maltose and maltodextrins
AM681_RS23260	COG0366	Alpha amylase catalytic
AM681_RS23265	COG2182	Extracellular solute-binding protein
AM681_RS23270	COG1175	transmembrane transport
AM681_RS23275	COG3833	ABC-type maltose transport systems, permease component
AM681_RS23280	COG3223	Belongs to the PsiE family
AM681_RS23290	COG0166	Belongs to the GPI family
AM681_RS23335	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM681_RS23405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM681_RS23430	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM681_RS23445	COG0395	ABC-type sugar transport system, permease component
AM681_RS23450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM681_RS23460	COG2188	Transcriptional regulator
AM681_RS23465	COG0646	methionine synthase
AM681_RS23465	COG1410	methionine synthase
AM681_RS23470	COG1414	Transcriptional regulator
AM681_RS23475	COG3265	gluconokinase activity
AM681_RS23480	COG2610	gluconate transmembrane transporter activity
AM681_RS23485	COG0129	dihydroxy-acid dehydratase activity
AM681_RS23490	COG0800	Aldolase
AM681_RS23495	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AM681_RS23505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM681_RS23510	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AM681_RS23545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM681_RS23550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM681_RS23555	COG0009	L-threonylcarbamoyladenylate synthase
AM681_RS23560	COG0551	DNA topoisomerase type I activity
AM681_RS23565	COG2922	Belongs to the Smg family
AM681_RS23570	COG0758	DNA mediated transformation
AM681_RS23575	COG0242	peptide deformylase activity
AM681_RS23580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM681_RS23585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM681_RS23585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM681_RS23590	COG0569	domain protein
AM681_RS23595	COG1970	mechanosensitive ion channel activity
AM681_RS23600	COG3036	rescue of stalled ribosome
AM681_RS23605	COG0789	Transcriptional regulator
AM681_RS23615	COG0203	ribosomal protein L17
AM681_RS23620	COG0202	RNA polymerase activity
AM681_RS23625	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM681_RS23630	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM681_RS23635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM681_RS23640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM681_RS23645	COG0201	protein transport
AM681_RS23655	COG1841	ribosomal large subunit assembly
AM681_RS23660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM681_RS23665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM681_RS23670	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM681_RS23710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM681_RS23715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AM681_RS23725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM681_RS23735	COG0089	rRNA binding
AM681_RS23740	COG0088	Forms part of the polypeptide exit tunnel
AM681_RS23745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM681_RS23750	COG0051	transcription antitermination factor activity, RNA binding
AM681_RS23765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM681_RS23775	COG0049	tRNA binding
AM681_RS23780	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM681_RS23785	COG2168	tRNA wobble position uridine thiolation
AM681_RS23790	COG2923	Belongs to the DsrF TusC family
AM681_RS23795	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM681_RS23800	COG2964	Protein conserved in bacteria
AM681_RS23805	COG0545	Peptidyl-prolyl cis-trans isomerase
AM681_RS23810	COG2900	Belongs to the SlyX family
AM681_RS23815	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM681_RS23820	COG1757	Na H antiporter
AM681_RS23825	COG1609	Transcriptional regulator
AM681_RS23830	COG1047	Peptidyl-prolyl cis-trans
AM681_RS23835	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM681_RS23845	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM681_RS23850	COG0488	(ABC) transporter
AM681_RS23855	COG2175	clavaminate synthase activity
AM681_RS23870	COG4521	taurine ABC transporter
AM681_RS23885	COG0429	hydrolase of the alpha beta-hydrolase fold
AM681_RS23890	COG3089	Belongs to the UPF0270 family
AM681_RS23895	COG3954	Phosphoribulokinase
AM681_RS23900	COG1765	OsmC-like protein
AM681_RS23905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM681_RS23910	COG1289	transmembrane transporter activity
AM681_RS23925	COG0433	COG0433 Predicted ATPase
AM681_RS23945	COG3275	phosphorelay sensor kinase activity
AM681_RS23950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM681_RS23960	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM681_RS23965	COG1486	melibiose metabolic process
AM681_RS23970	COG1609	Transcriptional regulator
AM681_RS23975	COG0738	Major facilitator superfamily
AM681_RS23995	COG0402	S-adenosylhomocysteine deaminase activity
AM681_RS24000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM681_RS24015	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM681_RS24015	COG1648	precorrin-2 dehydrogenase activity
AM681_RS24020	COG0180	Tryptophanyl-tRNA synthetase
AM681_RS24025	COG0546	phosphoglycolate phosphatase activity
AM681_RS24045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM681_RS24050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM681_RS24055	COG4796	Type ii and iii secretion system protein
AM681_RS24080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM681_RS24085	COG0494	nUDIX hydrolase
AM681_RS24095	COG1011	Hydrolase
AM681_RS24100	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM681_RS24105	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM681_RS24140	COG0484	heat shock protein binding
AM681_RS24145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM681_RS24150	COG2183	response to ionizing radiation
AM681_RS24155	COG1918	ferrous iron import across plasma membrane
AM681_RS24180	COG1040	competence protein
AM681_RS24185	COG0316	Belongs to the HesB IscA family
AM681_RS24185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM681_RS24190	COG1640	4-alpha-glucanotransferase
AM681_RS24195	COG0058	SHG alpha-glucan phosphorylase activity
AM681_RS24200	COG2909	trisaccharide binding
AM681_RS24205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM681_RS24210	COG0705	Rhomboid family
AM681_RS24215	COG1349	DNA-binding transcription factor activity
AM681_RS24220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM681_RS24225	COG0583	DNA-binding transcription factor activity
AM681_RS24235	COG1473	amidohydrolase
AM681_RS24250	COG0058	SHG alpha-glucan phosphorylase activity
AM681_RS24255	COG0297	glycogen (starch) synthase activity
AM681_RS24260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM681_RS24265	COG1523	belongs to the glycosyl hydrolase 13 family
AM681_RS24270	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AM681_RS24285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM681_RS24290	COG2095	MarC family integral membrane protein
AM681_RS24295	COG3265	gluconokinase activity
AM681_RS24300	COG2610	gluconate transmembrane transporter activity
AM681_RS24305	COG1609	Transcriptional regulator
AM681_RS24310	COG2188	Transcriptional regulator
AM681_RS24320	COG3457	Alanine racemase
AM681_RS24325	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM681_RS24330	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AM681_RS24365	COG1741	Belongs to the pirin family
AM681_RS24370	COG1247	-acetyltransferase
AM681_RS24375	COG3191	aminopeptidase activity
AM681_RS24380	COG1082	Xylose isomerase domain protein TIM barrel
AM681_RS24385	COG1082	Xylose isomerase domain protein TIM barrel
AM681_RS24390	COG0673	inositol 2-dehydrogenase activity
AM681_RS24395	COG3962	Belongs to the TPP enzyme family
AM681_RS24400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM681_RS24420	COG3718	enzyme involved in inositol metabolism
AM681_RS24430	COG2814	Major facilitator Superfamily
AM681_RS24430	COG0477	Major facilitator Superfamily
AM681_RS24440	COG0390	transport system, permease component
AM681_RS24445	COG4619	ABC transporter
AM681_RS24475	COG3188	usher protein
AM681_RS24480	COG3121	Chaperone
AM681_RS24500	COG2197	response regulator
AM681_RS24510	COG0697	spore germination
AM681_RS24550	COG2081	HI0933 family
AM681_RS24555	COG0306	phosphate transporter
AM681_RS24570	COG0583	DNA-binding transcription factor activity
AM681_RS24575	COG0589	response to stress
AM681_RS24590	COG1129	ABC transporter
AM681_RS24595	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM681_RS24600	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM681_RS24615	COG0742	ribosomal rna small subunit methyltransferase
AM681_RS24620	COG0339	signal peptide processing
AM681_RS24635	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM681_RS24640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM681_RS24650	COG2205	protein histidine kinase activity
AM681_RS24650	COG0784	Response regulator, receiver
AM681_RS24680	COG5441	Belongs to the UPF0261 family
AM681_RS24690	COG3678	ATP-independent chaperone mediated protein folding
AM681_RS24695	COG5001	Diguanylate cyclase
AM681_RS24700	COG1024	Enoyl-CoA hydratase
AM681_RS24705	COG1295	ribonuclease BN
AM681_RS24710	COG0477	Major facilitator Superfamily
AM681_RS24715	COG2134	cdp-diacylglycerol pyrophosphatase
AM681_RS24720	COG2982	Protein involved in outer membrane biogenesis
AM681_RS24725	COG2200	EAL domain
AM681_RS24730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM681_RS24740	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM681_RS24760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM681_RS24765	COG0129	dihydroxy-acid dehydratase activity
AM681_RS24770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM681_RS24775	COG3978	acetolactate synthase activity
AM681_RS24790	COG2814	Major facilitator Superfamily
AM681_RS24800	COG3085	chromosome segregation
AM681_RS24805	COG0583	DNA-binding transcription factor activity
AM681_RS24845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM681_RS24865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM681_RS24880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM681_RS24890	COG0678	peroxiredoxin activity
AM681_RS24890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM681_RS24895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM681_RS24910	COG0165	Argininosuccinate lyase
AM681_RS24915	COG0137	argininosuccinate synthase activity
AM681_RS24920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM681_RS24935	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AM681_RS24940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM681_RS24945	COG0460	homoserine dehydrogenase
AM681_RS24945	COG0527	aspartate kinase activity
AM681_RS24950	COG0626	cystathionine gamma-synthase activity
AM681_RS24955	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AM681_RS24960	COG0254	rRNA binding
AM681_RS24965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM681_RS24970	COG1609	Transcriptional regulator
AM681_RS24975	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM681_RS24980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AM681_RS24985	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AM681_RS24990	COG1575	Belongs to the MenA family. Type 1 subfamily
AM681_RS24995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM681_RS25000	COG3074	FtsZ-dependent cytokinesis
AM681_RS25015	COG1494	fructose-1,6-bisphosphatase
AM681_RS25020	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM681_RS25025	COG2814	Major facilitator Superfamily
AM681_RS25040	COG3152	Membrane
AM681_RS25050	COG0149	triose-phosphate isomerase activity
AM681_RS25055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM681_RS25065	COG0205	6-phosphofructokinase activity
AM681_RS25070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM681_RS25075	COG3678	ATP-independent chaperone mediated protein folding
AM681_RS25080	COG0745	RESPONSE REGULATOR receiver
AM681_RS25085	COG2205	protein histidine kinase activity
AM681_RS25090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM681_RS25125	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM681_RS25130	COG1045	serine acetyltransferase
AM681_RS25145	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM681_RS25150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM681_RS25155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM681_RS25160	COG4942	peptidase
AM681_RS25165	COG2861	carbohydrate metabolic process
AM681_RS25170	COG1063	alcohol dehydrogenase
AM681_RS25175	COG0156	8-amino-7-oxononanoate synthase activity
AM681_RS25180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM681_RS25185	COG0859	PFAM glycosyl transferase family 9
AM681_RS25190	COG0859	PFAM glycosyl transferase family 9
AM681_RS25195	COG0463	Glycosyl transferase, family 2
AM681_RS25200	COG1442	glycosyl transferase family 8
AM681_RS25220	COG0859	PFAM glycosyl transferase family 9
AM681_RS25225	COG0438	transferase activity, transferring glycosyl groups
AM681_RS25230	COG0438	transferase activity, transferring glycosyl groups
AM681_RS25240	COG1519	Transferase
AM681_RS25260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM681_RS25265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM681_RS25270	COG2003	Belongs to the UPF0758 family
AM681_RS25275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM681_RS25280	COG0756	dUTP diphosphatase activity
AM681_RS25285	COG1309	transcriptional regulator
AM681_RS25290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM681_RS25295	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM681_RS25300	COG1561	YicC-like family, N-terminal region
AM681_RS25385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM681_RS25395	COG2860	membrane
AM681_RS25400	COG0194	GDP metabolic process
AM681_RS25405	COG1758	RNA polymerase activity
AM681_RS25410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM681_RS25415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM681_RS25420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM681_RS25425	COG0786	glutamate:sodium symporter activity
AM681_RS25430	COG2233	PERMEase
AM681_RS25435	COG2982	Protein involved in outer membrane biogenesis
AM681_RS25440	COG0456	acetyltransferase
AM681_RS25445	COG1490	D-aminoacyl-tRNA deacylase activity
AM681_RS25450	COG1295	ribonuclease BN
AM681_RS25455	COG1011	Hydrolase
AM681_RS25460	COG1217	gtp-binding protein TYPA
AM681_RS25475	COG3852	Histidine kinase
AM681_RS25485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM681_RS25495	COG3078	GTPase activator activity
AM681_RS25505	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AM681_RS25510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM681_RS25510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM681_RS25515	COG0204	Acyl-transferase
AM681_RS25520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM681_RS25525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM681_RS25530	COG3084	Protein conserved in bacteria
AM681_RS25535	COG0746	molybdenum cofactor guanylyltransferase activity
AM681_RS25540	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM681_RS25565	COG2186	Transcriptional regulator
AM681_RS25570	COG0477	Major facilitator Superfamily
AM681_RS25575	COG1609	Transcriptional regulator
AM681_RS25580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM681_RS25590	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM681_RS25595	COG1129	ABC transporter
AM681_RS25600	COG1869	D-ribose catabolic process
AM681_RS25605	COG3158	transport of potassium into the cell
AM681_RS25610	COG0714	Associated with various cellular activities
AM681_RS25615	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM681_RS25620	COG2502	aspartate--ammonia ligase
AM681_RS25625	COG1522	sequence-specific DNA binding
AM681_RS25630	COG0716	FMN binding
AM681_RS25635	COG0445	tRNA wobble uridine modification
AM681_RS25640	COG0357	Ribosomal RNA small subunit methyltransferase G
AM681_RS25645	COG3312	ion transport
AM681_RS25660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM681_RS25665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM681_RS25670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM681_RS25675	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM681_RS25680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM681_RS25685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM681_RS25690	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM681_RS25700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM681_RS25705	COG0573	inorganic phosphate transmembrane transporter activity
AM681_RS25710	COG0581	inorganic phosphate transmembrane transporter activity
AM681_RS25720	COG0704	Plays a role in the regulation of phosphate uptake
AM681_RS25725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM681_RS25730	COG0765	amino acid transport
AM681_RS25735	COG0765	amino acid transport
AM681_RS25740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM681_RS25745	COG0494	nUDIX hydrolase
AM681_RS25750	COG2252	PERMEase
AM681_RS25760	COG0431	NADPH-dependent FMN reductase
AM681_RS25765	COG2091	lysine biosynthetic process via aminoadipic acid
AM681_RS25775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM681_RS25780	COG0706	membrane insertase activity
AM681_RS25785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM681_RS25790	COG0594	ribonuclease P activity
AM681_RS25900	COG3039	Transposase
AM681_RS25915	COG2894	cell division
AM681_RS25950	COG0484	heat shock protein binding
AM681_RS26095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM681_RS26160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM681_RS26170	COG0438	transferase activity, transferring glycosyl groups
AM681_RS26230	COG3039	Transposase
AM681_RS26280	COG2026	Addiction module toxin, RelE StbE family
AM681_RS26285	COG3077	Addiction module antitoxin, RelB DinJ family
AM681_RS26295	COG2826	transposase and inactivated derivatives, IS30 family
AM681_RS26305	COG4644	lycopene metabolic process
AM681_RS26315	COG2186	Transcriptional regulator
AM681_RS26325	COG0246	Mannitol dehydrogenase
AM681_RS26345	COG3039	Transposase
AM681_RS26365	COG1309	transcriptional regulator
AM681_RS26380	COG1136	(ABC) transporter
AM681_RS26420	COG0589	response to stress
AM681_RS26425	COG0659	secondary active sulfate transmembrane transporter activity
AM681_RS26480	COG2963	transposase activity
AM681_RS26485	COG2826	transposase and inactivated derivatives, IS30 family
AM681_RS26495	COG3436	PFAM IS66 Orf2 family protein
AM681_RS26500	COG2433	Pfam Transposase IS66
AM681_RS26550	COG2372	response to copper ion
AM681_RS26555	COG3667	copper resistance
AM681_RS26560	COG2132	Multicopper oxidase
AM681_RS26570	COG0739	heme binding
AM681_RS26600	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM681_RS27140	COG3621	Patatin-like phospholipase
AM681_RS27190	COG4372	Transposase
AM681_RS27195	COG3436	PFAM IS66 Orf2 family protein
AM681_RS27215	COG1401	restriction endodeoxyribonuclease activity
AM681_RS27215	COG1401	restriction endodeoxyribonuclease activity
AM681_RS27230	COG2801	Transposase and inactivated derivatives
AM681_RS27240	COG2801	Transposase and inactivated derivatives
AM681_RS27320	COG2205	protein histidine kinase activity
AM681_RS27390	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AM681_RS27405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM681_RS27415	COG0583	DNA-binding transcription factor activity
AM681_RS27425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM681_RS27430	COG0625	glutathione transferase activity
AM681_RS27460	COG3436	PFAM IS66 Orf2 family protein