locus-tag	class	description
AM354_RS00010	COG0500	methyltransferase
AM354_RS00015	COG2226	methyltransferase
AM354_RS00020	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM354_RS00025	COG1801	Protein of unknown function DUF72
AM354_RS00030	COG1335	isochorismatase
AM354_RS00040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM354_RS00045	COG0494	nUDIX hydrolase
AM354_RS00050	COG0217	transcriptional regulatory protein
AM354_RS00055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM354_RS00060	COG0632	four-way junction helicase activity
AM354_RS00065	COG2255	four-way junction helicase activity
AM354_RS00070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM354_RS00075	COG1121	(ABC) transporter
AM354_RS00080	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM354_RS00085	COG0739	heme binding
AM354_RS00090	COG1560	Kdo2-lipid A biosynthetic process
AM354_RS00100	COG0469	pyruvate kinase activity
AM354_RS00105	COG1737	Transcriptional regulator
AM354_RS00110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM354_RS00115	COG0800	Aldolase
AM354_RS00120	COG2076	Multidrug Resistance protein
AM354_RS00125	COG2076	Multidrug Resistance protein
AM354_RS00130	COG0251	oxidation-reduction process
AM354_RS00135	COG1199	ATP-dependent helicase activity
AM354_RS00145	COG3065	identical protein binding
AM354_RS00150	COG0318	PFAM AMP-dependent synthetase and ligase
AM354_RS00155	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM354_RS00160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AM354_RS00165	COG2894	cell division
AM354_RS00170	COG0850	regulation of cytokinetic process
AM354_RS00175	COG3100	YcgL domain-containing protein
AM354_RS00180	COG2951	lytic endotransglycosylase activity
AM354_RS00185	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM354_RS00190	COG2983	Belongs to the UPF0260 family
AM354_RS00195	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AM354_RS00200	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM354_RS00205	COG2186	Transcriptional regulator
AM354_RS00210	COG2719	SpoVR family
AM354_RS00215	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM354_RS00225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM354_RS00230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM354_RS00280	COG2718	Belongs to the UPF0229 family
AM354_RS00285	COG2766	serine protein kinase
AM354_RS00290	COG3713	MltA-interacting MipA family protein
AM354_RS00305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM354_RS00310	COG3139	Protein of unknown function (DUF1315)
AM354_RS00320	COG1335	isochorismatase
AM354_RS00325	COG0252	asparaginase activity
AM354_RS00330	COG0616	signal peptide processing
AM354_RS00335	COG0778	Nitroreductase
AM354_RS00345	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AM354_RS00350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM354_RS00360	COG0494	nUDIX hydrolase
AM354_RS00365	COG0708	Exodeoxyribonuclease III
AM354_RS00395	COG0788	formyltetrahydrofolate deformylase activity
AM354_RS00400	COG3012	SEC-C Motif Domain Protein
AM354_RS00405	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM354_RS00410	COG0745	RESPONSE REGULATOR receiver
AM354_RS00415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM354_RS00440	COG1454	alcohol dehydrogenase
AM354_RS00440	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS00445	COG2095	MarC family integral membrane protein
AM354_RS00450	COG4166	transmembrane transport
AM354_RS00465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM354_RS00470	COG0444	Belongs to the ABC transporter superfamily
AM354_RS00480	COG3099	Belongs to the UPF0263 family
AM354_RS00485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM354_RS00495	COG0783	Belongs to the Dps family
AM354_RS00510	COG1879	ABC-type sugar transport system periplasmic component
AM354_RS00515	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS00520	COG1129	ABC transporter
AM354_RS00525	COG1070	Carbohydrate kinase
AM354_RS00540	COG1609	Transcriptional regulator
AM354_RS00550	COG0583	DNA-binding transcription factor activity
AM354_RS00665	COG3179	chitinase
AM354_RS00745	COG0741	lytic transglycosylase activity
AM354_RS00770	COG2350	Protein conserved in bacteria
AM354_RS00775	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM354_RS00785	COG1607	acyl-coa hydrolase
AM354_RS00790	COG2917	probably involved in intracellular septation
AM354_RS00805	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM354_RS00820	COG0159	tryptophan synthase activity
AM354_RS00825	COG0133	tryptophan synthase activity
AM354_RS00835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM354_RS00850	COG0613	PHP domain protein
AM354_RS00855	COG0009	L-threonylcarbamoyladenylate synthase
AM354_RS00870	COG1187	pseudouridine synthase activity
AM354_RS00875	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM354_RS00880	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS00885	COG0616	signal peptide processing
AM354_RS00900	COG0583	DNA-binding transcription factor activity
AM354_RS00905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM354_RS00915	COG0671	phosphoesterase, PA-phosphatase related
AM354_RS00920	COG1349	DNA-binding transcription factor activity
AM354_RS00925	COG3959	Transketolase, thiamine diphosphate binding domain
AM354_RS00930	COG3958	Transketolase
AM354_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS00940	COG1879	ABC-type sugar transport system periplasmic component
AM354_RS00950	COG1129	ABC transporter
AM354_RS00955	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS00960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM354_RS00965	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS00970	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM354_RS00975	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM354_RS00995	COG0023	Translation Initiation Factor
AM354_RS01005	COG1349	DNA-binding transcription factor activity
AM354_RS01010	COG1882	Formate acetyltransferase
AM354_RS01015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM354_RS01020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM354_RS01025	COG2831	hemolysin activation secretion protein
AM354_RS01045	COG3210	domain, Protein
AM354_RS01090	COG3210	domain, Protein
AM354_RS01110	COG1966	Carbon starvation protein
AM354_RS01115	COG1473	amidohydrolase
AM354_RS01120	COG0477	Major facilitator Superfamily
AM354_RS01125	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AM354_RS01140	COG0243	molybdopterin cofactor binding
AM354_RS01160	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM354_RS01160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM354_RS01170	COG4172	Belongs to the ABC transporter superfamily
AM354_RS01175	COG4172	Belongs to the ABC transporter superfamily
AM354_RS01180	COG4171	peptide transport system, permease
AM354_RS01195	COG1469	GTP cyclohydrolase I activity
AM354_RS01210	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS01220	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM354_RS01225	COG1842	Phage shock protein A
AM354_RS01235	COG1983	PspC domain protein
AM354_RS01245	COG3106	COG3106 Predicted ATPase
AM354_RS01250	COG3768	UPF0283 membrane protein
AM354_RS01260	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM354_RS01265	COG4948	Mandelate Racemase Muconate Lactonizing
AM354_RS01270	COG2866	Carboxypeptidase
AM354_RS01280	COG4166	transmembrane transport
AM354_RS01310	COG0037	tRNA processing
AM354_RS01315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM354_RS01315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM354_RS01315	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM354_RS01315	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM354_RS01325	COG3042	response to heat
AM354_RS01330	COG3187	Heat shock protein
AM354_RS01335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM354_RS01350	COG2911	Protein conserved in bacteria
AM354_RS01360	COG3784	Protein of unknown function (DUF1318)
AM354_RS01365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM354_RS01370	COG1643	Atp-dependent helicase
AM354_RS01385	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS01390	COG3591	Belongs to the peptidase S1B family
AM354_RS01400	COG2267	carboxylic ester hydrolase activity
AM354_RS01405	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AM354_RS01410	COG2205	protein histidine kinase activity
AM354_RS01415	COG0745	RESPONSE REGULATOR receiver
AM354_RS01440	COG0531	amino acid
AM354_RS01450	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM354_RS01455	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM354_RS01460	COG0589	response to stress
AM354_RS01470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM354_RS01485	COG2222	sugar isomerase
AM354_RS01500	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AM354_RS01505	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM354_RS01525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM354_RS01545	COG0306	phosphate transporter
AM354_RS01650	COG0697	spore germination
AM354_RS01655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM354_RS01700	COG2239	Acts as a magnesium transporter
AM354_RS01710	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM354_RS01715	COG0483	inositol monophosphate 1-phosphatase activity
AM354_RS01720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM354_RS01730	COG0488	(ABC) transporter
AM354_RS01735	COG1196	nuclear chromosome segregation
AM354_RS01735	COG3264	Mechanosensitive ion channel
AM354_RS01750	COG2271	Major facilitator Superfamily
AM354_RS01755	COG0697	spore germination
AM354_RS01760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM354_RS01765	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS01790	COG2199	diguanylate cyclase activity
AM354_RS01795	COG5507	3-demethylubiquinone-9 3-methyltransferase
AM354_RS01805	COG3048	D-serine ammonia-lyase activity
AM354_RS01810	COG2814	Major facilitator Superfamily
AM354_RS01820	COG2723	6-phospho-beta-galactosidase activity
AM354_RS01825	COG1737	Transcriptional regulator
AM354_RS01830	COG2080	2 iron, 2 sulfur cluster binding
AM354_RS01835	COG2010	Cytochrome c
AM354_RS01835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM354_RS01840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM354_RS01840	COG2010	Cytochrome c
AM354_RS01845	COG0778	Nitroreductase
AM354_RS01870	COG3192	ethanolamine utilization protein
AM354_RS01875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM354_RS01890	COG1349	DNA-binding transcription factor activity
AM354_RS01895	COG0243	molybdopterin cofactor binding
AM354_RS01905	COG0583	DNA-binding transcription factor activity
AM354_RS01910	COG2957	Belongs to the agmatine deiminase family
AM354_RS01925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM354_RS01945	COG0789	Transcriptional regulator
AM354_RS01965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS01970	COG0693	protein deglycase activity
AM354_RS01975	COG0318	PFAM AMP-dependent synthetase and ligase
AM354_RS01980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM354_RS01990	COG4774	siderophore transport
AM354_RS01995	COG2382	esterase
AM354_RS02010	COG0477	Major facilitator Superfamily
AM354_RS02015	COG1733	regulation of RNA biosynthetic process
AM354_RS02020	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM354_RS02050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM354_RS02085	COG0673	inositol 2-dehydrogenase activity
AM354_RS02090	COG1082	Xylose isomerase domain protein TIM barrel
AM354_RS02095	COG1648	precorrin-2 dehydrogenase activity
AM354_RS02095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM354_RS02100	COG0243	molybdopterin cofactor binding
AM354_RS02105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM354_RS02105	COG2146	nitrite reductase [NAD(P)H] activity
AM354_RS02110	COG1116	anion transmembrane transporter activity
AM354_RS02115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM354_RS02120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM354_RS02125	COG3707	response regulator
AM354_RS02130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM354_RS02155	COG5002	protein histidine kinase activity
AM354_RS02155	COG3447	MASE1 domain protein
AM354_RS02155	COG5001	Diguanylate cyclase
AM354_RS02165	COG1902	pentaerythritol trinitrate reductase activity
AM354_RS02165	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM354_RS02170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM354_RS02175	COG0076	glutamate decarboxylase activity
AM354_RS02180	COG0583	DNA-binding transcription factor activity
AM354_RS02220	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM354_RS02225	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS02230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM354_RS02235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM354_RS02240	COG2267	carboxylic ester hydrolase activity
AM354_RS02250	COG1802	Transcriptional regulator
AM354_RS02270	COG5001	Diguanylate cyclase
AM354_RS02270	COG3300	MHYT domain
AM354_RS02275	COG2814	Major facilitator Superfamily
AM354_RS02285	COG3284	Transcriptional regulator
AM354_RS02295	COG1064	alcohol dehydrogenase
AM354_RS02300	COG3453	Protein conserved in bacteria
AM354_RS02300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM354_RS02310	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM354_RS02325	COG2862	Uncharacterized protein family, UPF0114
AM354_RS02330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM354_RS02350	COG2814	Major facilitator Superfamily
AM354_RS02355	COG0673	inositol 2-dehydrogenase activity
AM354_RS02360	COG1349	DNA-binding transcription factor activity
AM354_RS02370	COG2814	Major facilitator Superfamily
AM354_RS02380	COG0583	DNA-binding transcription factor activity
AM354_RS02405	COG0840	transmembrane signaling receptor activity
AM354_RS02420	COG0768	penicillin binding
AM354_RS02440	COG2814	Major facilitator Superfamily
AM354_RS02505	COG0596	Alpha beta hydrolase
AM354_RS02540	COG2140	Oxalate decarboxylase
AM354_RS02600	COG0583	DNA-binding transcription factor activity
AM354_RS02610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM354_RS02610	COG2010	Cytochrome c
AM354_RS02615	COG2080	2 iron, 2 sulfur cluster binding
AM354_RS02620	COG1846	Transcriptional regulator
AM354_RS02625	COG2309	aminopeptidase activity
AM354_RS02630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM354_RS02635	COG0596	Alpha beta hydrolase
AM354_RS02640	COG3473	Maleate cis-trans isomerase
AM354_RS02645	COG1335	isochorismatase
AM354_RS02650	COG2271	Major facilitator Superfamily
AM354_RS02655	COG0339	signal peptide processing
AM354_RS02665	COG0402	S-adenosylhomocysteine deaminase activity
AM354_RS02670	COG1595	DNA-templated transcription, initiation
AM354_RS02675	COG3712	iron ion homeostasis
AM354_RS02680	COG4772	TonB-dependent receptor
AM354_RS02690	COG4221	oxidoreductase activity
AM354_RS02695	COG1742	UPF0060 membrane protein
AM354_RS02710	COG0477	Major facilitator Superfamily
AM354_RS02740	COG0789	Transcriptional regulator
AM354_RS02750	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM354_RS02755	COG1940	carbohydrate kinase activity
AM354_RS02760	COG0583	DNA-binding transcription factor activity
AM354_RS02765	COG2814	Major facilitator Superfamily
AM354_RS02770	COG1649	PFAM Uncharacterised BCR, COG1649
AM354_RS02775	COG1472	Belongs to the glycosyl hydrolase 3 family
AM354_RS02790	COG2378	regulation of single-species biofilm formation
AM354_RS02795	COG0114	fumarate hydratase activity
AM354_RS02810	COG5339	Protein conserved in bacteria
AM354_RS02820	COG0583	DNA-binding transcription factor activity
AM354_RS02835	COG1609	Transcriptional regulator
AM354_RS02840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS02840	COG1263	PTS System
AM354_RS02845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM354_RS02855	COG0494	nUDIX hydrolase
AM354_RS02860	COG1349	DNA-binding transcription factor activity
AM354_RS02865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM354_RS02875	COG0385	Bile acid
AM354_RS02880	COG0673	inositol 2-dehydrogenase activity
AM354_RS02890	COG4657	Part of a membrane complex involved in electron transport
AM354_RS02895	COG2878	Part of a membrane complex involved in electron transport
AM354_RS02900	COG4656	Part of a membrane complex involved in electron transport
AM354_RS02905	COG2207	Transcriptional regulator
AM354_RS02905	COG3708	Transcriptional regulator
AM354_RS02915	COG4659	FMN binding
AM354_RS02925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM354_RS02930	COG3104	oligopeptide transport
AM354_RS02935	COG1505	serine-type exopeptidase activity
AM354_RS02940	COG1396	sequence-specific DNA binding
AM354_RS02945	COG3135	benzoate transporter
AM354_RS02980	COG1418	mRNA catabolic process
AM354_RS02995	COG0625	glutathione transferase activity
AM354_RS03005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM354_RS03010	COG0259	pyridoxamine-phosphate oxidase activity
AM354_RS03020	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM354_RS03025	COG3133	Outer membrane lipoprotein
AM354_RS03030	COG1846	Transcriptional regulator
AM354_RS03040	COG1566	PFAM secretion protein HlyD family protein
AM354_RS03045	COG1289	transmembrane transporter activity
AM354_RS03055	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM354_RS03060	COG4989	oxidoreductase activity
AM354_RS03065	COG3313	Fe-S protein
AM354_RS03070	COG0583	DNA-binding transcription factor activity
AM354_RS03080	COG2194	sulfuric ester hydrolase activity
AM354_RS03085	COG1309	transcriptional regulator
AM354_RS03090	COG1902	pentaerythritol trinitrate reductase activity
AM354_RS03095	COG0346	lactoylglutathione lyase activity
AM354_RS03105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM354_RS03110	COG0791	NLP P60 protein
AM354_RS03125	COG1609	Transcriptional regulator
AM354_RS03130	COG0583	DNA-binding transcription factor activity
AM354_RS03135	COG2814	Major facilitator Superfamily
AM354_RS03140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM354_RS03150	COG0307	riboflavin synthase, alpha
AM354_RS03155	COG0534	Mate efflux family protein
AM354_RS03180	COG0469	pyruvate kinase activity
AM354_RS03190	COG1376	ErfK ybiS ycfS ynhG family protein
AM354_RS03190	COG1388	LysM domain
AM354_RS03195	COG2166	iron-sulfur cluster assembly
AM354_RS03200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM354_RS03205	COG0719	Fe-S assembly protein
AM354_RS03210	COG0396	ATPase activity
AM354_RS03215	COG0719	Fe-S assembly protein
AM354_RS03220	COG0316	Belongs to the HesB IscA family
AM354_RS03230	COG2050	protein possibly involved in aromatic compounds catabolism
AM354_RS03235	COG0277	FAD linked oxidase domain protein
AM354_RS03235	COG0247	lactate metabolic process
AM354_RS03240	COG0628	permease
AM354_RS03250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM354_RS03250	COG0574	Belongs to the PEP-utilizing enzyme family
AM354_RS03260	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AM354_RS03265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM354_RS03270	COG0386	Belongs to the glutathione peroxidase family
AM354_RS03285	COG3720	iron ion transport
AM354_RS03290	COG4558	Periplasmic binding protein
AM354_RS03295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS03315	COG0095	Lipoate-protein ligase
AM354_RS03320	COG0791	NLP P60 protein
AM354_RS03325	COG2076	Multidrug Resistance protein
AM354_RS03330	COG2076	Multidrug Resistance protein
AM354_RS03335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM354_RS03340	COG0726	polysaccharide deacetylase
AM354_RS03345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM354_RS03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM354_RS03350	COG1215	transferase activity, transferring glycosyl groups
AM354_RS03355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM354_RS03365	COG0386	Belongs to the glutathione peroxidase family
AM354_RS03370	COG4139	cobalamin transport
AM354_RS03390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM354_RS03395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM354_RS03400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM354_RS03410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM354_RS03435	COG0814	amino acid
AM354_RS03465	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM354_RS03470	COG1121	(ABC) transporter
AM354_RS03475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM354_RS03480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM354_RS03485	COG3001	Fructosamine kinase
AM354_RS03500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM354_RS03505	COG1988	membrane-bound metal-dependent
AM354_RS03510	COG1823	symporter activity
AM354_RS03525	COG2188	Transcriptional regulator
AM354_RS03550	COG1414	Transcriptional regulator
AM354_RS03555	COG2814	Major facilitator Superfamily
AM354_RS03560	COG0501	Belongs to the peptidase M48B family
AM354_RS03565	COG0793	Belongs to the peptidase S41A family
AM354_RS03570	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM354_RS03575	COG1956	GAF domain-containing protein
AM354_RS03580	COG2995	paraquat-inducible protein a
AM354_RS03585	COG3008	intermembrane lipid transfer
AM354_RS03590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM354_RS03590	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AM354_RS03650	COG3493	citrate carrier protein
AM354_RS03655	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AM354_RS03660	COG0477	Major facilitator Superfamily
AM354_RS03665	COG2211	Major facilitator Superfamily
AM354_RS03685	COG0402	S-adenosylhomocysteine deaminase activity
AM354_RS03695	COG1228	amidohydrolase
AM354_RS03710	COG1605	Chorismate mutase
AM354_RS03740	COG0531	amino acid
AM354_RS03750	COG0174	glutamine synthetase
AM354_RS03755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM354_RS03760	COG1917	Cupin 2, conserved barrel domain protein
AM354_RS03760	COG1396	sequence-specific DNA binding
AM354_RS03765	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS03770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM354_RS03775	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS03780	COG0589	response to stress
AM354_RS03785	COG1335	isochorismatase
AM354_RS03795	COG1278	Cold shock
AM354_RS03855	COG3064	Membrane
AM354_RS03920	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM354_RS03925	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM354_RS03980	COG0616	signal peptide processing
AM354_RS04000	COG4220	transposase activity
AM354_RS04045	COG1403	HNH endonuclease
AM354_RS04140	COG0582	viral genome integration into host DNA
AM354_RS04150	COG0538	isocitrate dehydrogenase activity
AM354_RS04155	COG1187	pseudouridine synthase activity
AM354_RS04170	COG0482	sulfurtransferase activity
AM354_RS04180	COG2915	High frequency lysogenization protein hflD homolog
AM354_RS04185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM354_RS04190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM354_RS04205	COG2188	Transcriptional regulator
AM354_RS04210	COG1397	ADP-ribosylglycohydrolase
AM354_RS04215	COG0745	RESPONSE REGULATOR receiver
AM354_RS04225	COG2850	peptidyl-arginine hydroxylation
AM354_RS04230	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM354_RS04235	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM354_RS04250	COG1177	transmembrane transport
AM354_RS04255	COG1263	PTS System
AM354_RS04255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS04260	COG1486	melibiose metabolic process
AM354_RS04285	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM354_RS04295	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM354_RS04300	COG1045	serine acetyltransferase
AM354_RS04305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM354_RS04310	COG4702	Belongs to the UPF0303 family
AM354_RS04315	COG0659	secondary active sulfate transmembrane transporter activity
AM354_RS04320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM354_RS04325	COG2912	Transglutaminase-like superfamily
AM354_RS04330	COG3094	Invasion gene expression up-regulator, SirB
AM354_RS04335	COG2890	protein-(glutamine-N5) methyltransferase activity
AM354_RS04340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM354_RS04345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM354_RS04350	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM354_RS04355	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM354_RS04360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM354_RS04370	COG0193	aminoacyl-tRNA hydrolase activity
AM354_RS04375	COG0659	secondary active sulfate transmembrane transporter activity
AM354_RS04380	COG0012	GTP binding
AM354_RS04390	COG0442	prolyl-tRNA aminoacylation
AM354_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS04395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM354_RS04395	COG0318	PFAM AMP-dependent synthetase and ligase
AM354_RS04395	COG0300	oxidoreductase activity
AM354_RS04395	COG3321	synthase
AM354_RS04400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM354_RS04410	COG4221	oxidoreductase activity
AM354_RS04425	COG2423	ornithine cyclodeaminase activity
AM354_RS04435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM354_RS04445	COG0740	serine-type endopeptidase activity
AM354_RS04455	COG0640	Transcriptional regulator
AM354_RS04460	COG0531	amino acid
AM354_RS04465	COG2731	YhcH YjgK YiaL family protein
AM354_RS04470	COG3250	beta-galactosidase activity
AM354_RS04475	COG1609	Transcriptional regulator
AM354_RS04485	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AM354_RS04485	COG3408	Glycogen debranching enzyme
AM354_RS04490	COG0589	response to stress
AM354_RS04500	COG1464	Belongs to the NlpA lipoprotein family
AM354_RS04505	COG2358	TRAP transporter, solute receptor (TAXI family
AM354_RS04520	COG0579	oxidoreductase
AM354_RS04535	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS04540	COG1129	ABC transporter
AM354_RS04555	COG3290	protein histidine kinase activity
AM354_RS04560	COG4565	transcriptional regulatory protein
AM354_RS04580	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM354_RS04605	COG1276	copper resistance
AM354_RS04610	COG2372	response to copper ion
AM354_RS04615	COG1528	Iron-storage protein
AM354_RS04635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM354_RS04640	COG1770	oligopeptidase
AM354_RS04645	COG2979	Protein of unknown function (DUF533)
AM354_RS04650	COG3381	protein complex oligomerization
AM354_RS04655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AM354_RS04660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM354_RS04695	COG2207	Transcriptional regulator
AM354_RS04695	COG3708	Transcriptional regulator
AM354_RS04700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS04715	COG3134	Outer membrane lipoprotein
AM354_RS04720	COG1252	NADH dehydrogenase
AM354_RS04725	COG3150	esterase
AM354_RS04740	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AM354_RS04745	COG5633	Lipoprotein
AM354_RS04750	COG0537	adenosine 5'-monophosphoramidase activity
AM354_RS04755	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM354_RS04760	COG1733	regulation of RNA biosynthetic process
AM354_RS04765	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS04770	COG1914	H( )-stimulated, divalent metal cation uptake system
AM354_RS04775	COG1321	iron dependent repressor
AM354_RS04785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS04785	COG1263	PTS System
AM354_RS04790	COG0084	hydrolase, TatD family'
AM354_RS04795	COG0470	DNA polymerase III
AM354_RS04800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM354_RS04805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM354_RS04810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM354_RS04815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM354_RS04820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM354_RS04830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM354_RS04835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM354_RS04840	COG0416	fatty acid biosynthetic process
AM354_RS04845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM354_RS04850	COG1399	metal-binding, possibly nucleic acid-binding protein
AM354_RS04860	COG0564	pseudouridine synthase activity
AM354_RS04870	COG1530	ribonuclease E activity
AM354_RS04875	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM354_RS04880	COG0418	dihydroorotase activity
AM354_RS04920	COG0628	permease
AM354_RS04925	COG3038	cytochrome b561
AM354_RS04930	COG2353	YceI-like domain
AM354_RS04935	COG1054	Belongs to the UPF0176 family
AM354_RS04945	COG1560	Kdo2-lipid A biosynthetic process
AM354_RS04955	COG2814	Major facilitator Superfamily
AM354_RS04965	COG0346	lactoylglutathione lyase activity
AM354_RS04980	COG0640	Transcriptional regulator
AM354_RS04990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM354_RS05005	COG5645	(Lipo)protein
AM354_RS05010	COG2943	transferase activity, transferring hexosyl groups
AM354_RS05015	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AM354_RS05050	COG0322	excinuclease ABC activity
AM354_RS05055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS05065	COG1538	Outer membrane efflux protein
AM354_RS05100	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM354_RS05125	COG0322	excinuclease ABC activity
AM354_RS05130	COG2197	response regulator
AM354_RS05140	COG3136	membrane protein required for alginate biosynthesis
AM354_RS05155	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM354_RS05180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM354_RS05185	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS05190	COG0531	amino acid
AM354_RS05205	COG0589	response to stress
AM354_RS05210	COG2197	response regulator
AM354_RS05215	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM354_RS05220	COG0183	Belongs to the thiolase family
AM354_RS05225	COG0156	8-amino-7-oxononanoate synthase activity
AM354_RS05230	COG2814	Major facilitator Superfamily
AM354_RS05255	COG2271	Major facilitator Superfamily
AM354_RS05270	COG1113	amino acid transport
AM354_RS05285	COG0655	NAD(P)H dehydrogenase (quinone) activity
AM354_RS05295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM354_RS05305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM354_RS05310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS05320	COG0789	Transcriptional regulator
AM354_RS05340	COG3188	usher protein
AM354_RS05345	COG3121	Chaperone
AM354_RS05355	COG2197	response regulator
AM354_RS05380	COG0670	Belongs to the BI1 family
AM354_RS05385	COG2920	part of a sulfur-relay system
AM354_RS05390	COG1254	Belongs to the acylphosphatase family
AM354_RS05395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM354_RS05400	COG3785	DNA binding
AM354_RS05405	COG1832	CoA-binding protein
AM354_RS05415	COG1803	Methylglyoxal synthase
AM354_RS05420	COG0210	DNA helicase
AM354_RS05425	COG3304	Inner membrane component domain
AM354_RS05430	COG1289	transmembrane transporter activity
AM354_RS05435	COG3070	regulator of competence-specific genes
AM354_RS05455	COG1067	ATP-dependent peptidase activity
AM354_RS05460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM354_RS05470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM354_RS05475	COG3130	regulation of translation
AM354_RS05480	COG3009	Protein conserved in bacteria
AM354_RS05485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM354_RS05485	COG3008	intermembrane lipid transfer
AM354_RS05490	COG2995	paraquat-inducible protein a
AM354_RS05495	COG0488	(ABC) transporter
AM354_RS05500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM354_RS05500	COG0116	Belongs to the methyltransferase superfamily
AM354_RS05505	COG3217	Mosc domain protein beta barrel domain protein
AM354_RS05505	COG0633	Ferredoxin
AM354_RS05515	COG0167	dihydroorotate dehydrogenase activity
AM354_RS05520	COG0431	NADPH-dependent FMN reductase
AM354_RS05525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM354_RS05530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM354_RS05535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM354_RS05545	COG0308	aminopeptidase N
AM354_RS05550	COG3706	GGDEF domain
AM354_RS05555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AM354_RS05570	COG1448	Aminotransferase
AM354_RS05575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM354_RS05580	COG3108	Peptidase M15
AM354_RS05585	COG2989	Protein conserved in bacteria
AM354_RS05590	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM354_RS05600	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AM354_RS05605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM354_RS05610	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM354_RS05615	COG3173	Aminoglycoside phosphotransferase
AM354_RS05620	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM354_RS05625	COG2835	tetraacyldisaccharide 4'-kinase activity
AM354_RS05630	COG3214	Protein conserved in bacteria
AM354_RS05635	COG1278	Cold shock
AM354_RS05645	COG5383	Protein conserved in bacteria
AM354_RS05650	COG1663	tetraacyldisaccharide 4'-kinase activity
AM354_RS05655	COG1132	(ABC) transporter
AM354_RS05660	COG0658	competence protein
AM354_RS05660	COG2333	competence protein COMEC
AM354_RS05670	COG0539	negative regulation of cytoplasmic translation
AM354_RS05675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM354_RS05680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM354_RS05685	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AM354_RS05690	COG0252	asparaginase activity
AM354_RS05695	COG1944	ATP diphosphatase activity
AM354_RS05700	COG2116	formate transmembrane transporter activity
AM354_RS05705	COG1882	Formate acetyltransferase
AM354_RS05710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM354_RS05715	COG2814	Major facilitator Superfamily
AM354_RS05725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM354_RS05730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM354_RS05735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM354_RS05740	COG3107	peptidoglycan biosynthetic process
AM354_RS05740	COG1674	ftsk spoiiie
AM354_RS05750	COG0492	ferredoxin-NADP+ reductase activity
AM354_RS05760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM354_RS05765	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM354_RS05770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM354_RS05775	COG0542	response to heat
AM354_RS05780	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM354_RS05785	COG1278	Cold shock
AM354_RS05795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS05800	COG2990	Protein conserved in bacteria
AM354_RS05805	COG3593	DNA synthesis involved in DNA repair
AM354_RS05810	COG2431	L-lysine efflux transmembrane transporter activity
AM354_RS05815	COG1151	hydroxylamine reductase activity
AM354_RS05820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM354_RS05825	COG0028	Belongs to the TPP enzyme family
AM354_RS05830	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM354_RS05835	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AM354_RS05840	COG2190	(PTS) system
AM354_RS05840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS05840	COG1263	PTS System
AM354_RS05845	COG1737	Transcriptional regulator
AM354_RS05855	COG0702	epimerase
AM354_RS05860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM354_RS05865	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM354_RS05870	COG0393	Putative heavy-metal-binding
AM354_RS05880	COG1126	abc transporter atp-binding protein
AM354_RS05885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM354_RS05890	COG4215	(ABC) transporter
AM354_RS05895	COG4160	amino acid transport
AM354_RS05900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM354_RS05905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM354_RS05915	COG1177	transmembrane transport
AM354_RS05920	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM354_RS05925	COG3842	ATPase activity
AM354_RS05930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM354_RS05940	COG0189	ligase activity
AM354_RS05960	COG2985	domain, Protein
AM354_RS05960	COG0569	domain protein
AM354_RS05980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM354_RS05985	COG3395	kinase activity
AM354_RS05995	COG4574	serine-type endopeptidase inhibitor activity
AM354_RS06010	COG0671	phosphoesterase, PA-phosphatase related
AM354_RS06020	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM354_RS06025	COG1349	DNA-binding transcription factor activity
AM354_RS06030	COG0814	amino acid
AM354_RS06035	COG1760	l-serine dehydratase
AM354_RS06040	COG2197	response regulator
AM354_RS06045	COG0545	Peptidyl-prolyl cis-trans isomerase
AM354_RS06065	COG3121	Chaperone
AM354_RS06070	COG3188	usher protein
AM354_RS06075	COG3539	Fimbrial protein
AM354_RS06100	COG1686	Belongs to the peptidase S11 family
AM354_RS06110	COG0626	cystathionine gamma-synthase activity
AM354_RS06125	COG0625	glutathione transferase activity
AM354_RS06130	COG2133	pyrroloquinoline quinone binding
AM354_RS06140	COG0598	Magnesium transport protein CorA
AM354_RS06145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM354_RS06145	COG3153	acetyltransferase
AM354_RS06150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM354_RS06165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM354_RS06175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM354_RS06180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM354_RS06185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM354_RS06200	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM354_RS06205	COG0107	imidazoleglycerol-phosphate synthase activity
AM354_RS06210	COG0140	phosphoribosyl-ATP diphosphatase activity
AM354_RS06210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM354_RS06215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM354_RS06225	COG0438	transferase activity, transferring glycosyl groups
AM354_RS06235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM354_RS06265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM354_RS06305	COG0438	transferase activity, transferring glycosyl groups
AM354_RS06335	COG0489	protein tyrosine kinase activity
AM354_RS06335	COG3206	protein involved in exopolysaccharide biosynthesis
AM354_RS06355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM354_RS06360	COG1253	flavin adenine dinucleotide binding
AM354_RS06365	COG3069	C4-dicarboxylate transmembrane transporter activity
AM354_RS06370	COG2982	Protein involved in outer membrane biogenesis
AM354_RS06375	COG0717	Belongs to the dCTP deaminase family
AM354_RS06380	COG0572	uridine kinase
AM354_RS06390	COG0489	protein tyrosine kinase activity
AM354_RS06395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM354_RS06395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM354_RS06405	COG2814	Major facilitator Superfamily
AM354_RS06410	COG1380	Effector of murein hydrolase LrgA
AM354_RS06415	COG1346	cytolysis
AM354_RS06420	COG0295	cytidine deaminase activity
AM354_RS06425	COG0281	malic enzyme
AM354_RS06430	COG2949	membrane
AM354_RS06450	COG1609	Transcriptional regulator
AM354_RS06455	COG2311	Membrane
AM354_RS06460	COG0302	gtp cyclohydrolase
AM354_RS06465	COG0477	Major facilitator Superfamily
AM354_RS06470	COG0583	DNA-binding transcription factor activity
AM354_RS06485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM354_RS06490	COG0601	transmembrane transport
AM354_RS06495	COG0747	negative chemotaxis
AM354_RS06500	COG4172	Belongs to the ABC transporter superfamily
AM354_RS06515	COG0303	'Molybdopterin
AM354_RS06520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM354_RS06525	COG0488	(ABC) transporter
AM354_RS06535	COG0583	DNA-binding transcription factor activity
AM354_RS06545	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AM354_RS06560	COG0583	DNA-binding transcription factor activity
AM354_RS06565	COG1335	isochorismatase
AM354_RS06575	COG0640	Transcriptional regulator
AM354_RS06580	COG0625	glutathione transferase activity
AM354_RS06590	COG0579	oxidoreductase
AM354_RS06595	COG3708	Transcriptional regulator
AM354_RS06595	COG2207	Transcriptional regulator
AM354_RS06605	COG3188	usher protein
AM354_RS06610	COG3121	Chaperone
AM354_RS06620	COG2200	EAL domain
AM354_RS06630	COG0069	glutamate synthase activity
AM354_RS06635	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM354_RS06640	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS06645	COG1309	transcriptional regulator
AM354_RS06650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM354_RS06665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM354_RS06670	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM354_RS06675	COG0745	RESPONSE REGULATOR receiver
AM354_RS06680	COG5002	protein histidine kinase activity
AM354_RS06695	COG3188	usher protein
AM354_RS06735	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM354_RS06740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM354_RS06750	COG1349	DNA-binding transcription factor activity
AM354_RS06755	COG2084	Dehydrogenase
AM354_RS06760	COG3395	kinase activity
AM354_RS06765	COG0235	Class ii aldolase
AM354_RS06770	COG3622	Belongs to the hyi family
AM354_RS06775	COG2610	gluconate transmembrane transporter activity
AM354_RS06790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM354_RS06795	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM354_RS06805	COG2731	YhcH YjgK YiaL family protein
AM354_RS06820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM354_RS06825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM354_RS06830	COG0765	amino acid transport
AM354_RS06835	COG1126	abc transporter atp-binding protein
AM354_RS06840	COG0668	transmembrane transport
AM354_RS06850	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AM354_RS06855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM354_RS06875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM354_RS06885	COG0477	Major facilitator Superfamily
AM354_RS06895	COG1280	lysine exporter protein (LysE YggA)
AM354_RS06900	COG2079	MmgE PrpD family protein
AM354_RS06920	COG0697	spore germination
AM354_RS06925	COG1522	sequence-specific DNA binding
AM354_RS06935	COG1942	4-Oxalocrotonate Tautomerase
AM354_RS06940	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM354_RS06945	COG0625	glutathione transferase activity
AM354_RS06960	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AM354_RS06995	COG0697	spore germination
AM354_RS07015	COG1174	glycine betaine transport
AM354_RS07020	COG1125	glycine betaine transport
AM354_RS07025	COG1174	glycine betaine transport
AM354_RS07030	COG1732	Glycine betaine
AM354_RS07045	COG0583	DNA-binding transcription factor activity
AM354_RS07050	COG1335	isochorismatase
AM354_RS07060	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AM354_RS07070	COG0625	glutathione transferase activity
AM354_RS07080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM354_RS07085	COG0494	nUDIX hydrolase
AM354_RS07090	COG2897	thiosulfate sulfurtransferase activity
AM354_RS07095	COG0583	DNA-binding transcription factor activity
AM354_RS07135	COG0411	ABC transporter
AM354_RS07155	COG1802	Transcriptional regulator
AM354_RS07175	COG4807	Protein conserved in bacteria
AM354_RS07190	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM354_RS07205	COG2084	Dehydrogenase
AM354_RS07225	COG0519	Catalyzes the synthesis of GMP from XMP
AM354_RS07230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM354_RS07235	COG2011	ABC-type metal ion transport system permease component
AM354_RS07240	COG1464	Belongs to the NlpA lipoprotein family
AM354_RS07245	COG1309	transcriptional regulator
AM354_RS07260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM354_RS07315	COG0697	spore germination
AM354_RS07320	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM354_RS07325	COG1070	Carbohydrate kinase
AM354_RS07335	COG0583	DNA-binding transcription factor activity
AM354_RS07345	COG1192	Involved in chromosome partitioning
AM354_RS07375	COG2134	cdp-diacylglycerol pyrophosphatase
AM354_RS07380	COG0596	Alpha beta hydrolase
AM354_RS07390	COG1120	ATPase activity
AM354_RS07395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS07400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM354_RS07420	COG1472	Belongs to the glycosyl hydrolase 3 family
AM354_RS07430	COG0436	Aminotransferase
AM354_RS07440	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM354_RS07455	COG0277	FAD linked oxidase domain protein
AM354_RS07460	COG0840	transmembrane signaling receptor activity
AM354_RS07470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS07485	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM354_RS07505	COG0456	acetyltransferase
AM354_RS07515	COG1464	Belongs to the NlpA lipoprotein family
AM354_RS07525	COG2354	Protein conserved in bacteria
AM354_RS07545	COG1686	Belongs to the peptidase S11 family
AM354_RS07550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM354_RS07555	COG4977	sequence-specific DNA binding
AM354_RS07565	COG0586	Pfam SNARE associated Golgi protein
AM354_RS07570	COG0583	DNA-binding transcription factor activity
AM354_RS07590	COG0583	DNA-binding transcription factor activity
AM354_RS07595	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS07615	COG2271	Major facilitator Superfamily
AM354_RS07620	COG1840	ABC-type Fe3 transport system, periplasmic component
AM354_RS07630	COG3842	ATPase activity
AM354_RS07640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM354_RS07645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM354_RS07650	COG0513	Belongs to the DEAD box helicase family
AM354_RS07655	COG1309	transcriptional regulator
AM354_RS07660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS07665	COG1131	(ABC) transporter
AM354_RS07670	COG0842	Transport permease protein
AM354_RS07675	COG0842	Transport permease protein
AM354_RS07680	COG0670	Belongs to the BI1 family
AM354_RS07685	COG0314	molybdopterin synthase activity
AM354_RS07690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM354_RS07695	COG0315	cyclic pyranopterin monophosphate synthase activity
AM354_RS07700	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM354_RS07705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM354_RS07710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM354_RS07715	COG4628	conserved protein (DUF2132)
AM354_RS07720	COG0556	nucleotide-excision repair
AM354_RS07760	COG1881	PFAM PEBP family protein
AM354_RS07765	COG2706	6-phosphogluconolactonase activity
AM354_RS07770	COG0561	phosphatase activity
AM354_RS07780	COG4149	molybdate abc transporter
AM354_RS07785	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM354_RS07795	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM354_RS07800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS07805	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM354_RS07815	COG4774	siderophore transport
AM354_RS07820	COG3585	molybdate ion transport
AM354_RS07820	COG2005	Transcriptional regulator
AM354_RS07825	COG1119	ATPase activity
AM354_RS07845	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AM354_RS07850	COG2017	converts alpha-aldose to the beta-anomer
AM354_RS07860	COG0588	phosphoglycerate mutase activity
AM354_RS07875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM354_RS07880	COG2197	response regulator
AM354_RS07885	COG2205	protein histidine kinase activity
AM354_RS07885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM354_RS07890	COG1230	cation diffusion facilitator family transporter
AM354_RS07900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM354_RS07945	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM354_RS07950	COG2885	chlorophyll binding
AM354_RS07955	COG0823	Involved in the tonB-independent uptake of proteins
AM354_RS07960	COG3064	Membrane
AM354_RS07960	COG3064	Membrane
AM354_RS07965	COG0848	biopolymer transport protein
AM354_RS07970	COG0811	peptide transport
AM354_RS07975	COG0824	Thioesterase
AM354_RS07980	COG3790	cyd operon protein YbgE
AM354_RS07985	COG4890	Cyd operon protein YbgT
AM354_RS07990	COG1294	oxidase, subunit
AM354_RS07995	COG1271	oxidase subunit
AM354_RS08000	COG0737	Belongs to the 5'-nucleotidase family
AM354_RS08005	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM354_RS08010	COG0045	succinate-CoA ligase (ADP-forming) activity
AM354_RS08015	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM354_RS08020	COG0567	Dehydrogenase, E1 component
AM354_RS08025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM354_RS08030	COG1053	succinate dehydrogenase
AM354_RS08035	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM354_RS08070	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AM354_RS08075	COG1984	allophanate hydrolase subunit 2
AM354_RS08080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM354_RS08085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM354_RS08090	COG5212	phosphodiesterase
AM354_RS08100	COG3272	Protein of unknown function (DUF1722)
AM354_RS08115	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM354_RS08120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM354_RS08125	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AM354_RS08130	COG2205	protein histidine kinase activity
AM354_RS08135	COG0745	RESPONSE REGULATOR receiver
AM354_RS08145	COG1695	Transcriptional regulator
AM354_RS08150	COG0033	Phosphoglucomutase
AM354_RS08155	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AM354_RS08160	COG0596	Alpha beta hydrolase
AM354_RS08175	COG0735	belongs to the Fur family
AM354_RS08195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM354_RS08200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS08200	COG1263	PTS System
AM354_RS08200	COG2190	(PTS) system
AM354_RS08205	COG0363	glucosamine-6-phosphate deaminase activity
AM354_RS08210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM354_RS08215	COG1940	carbohydrate kinase activity
AM354_RS08215	COG1846	Transcriptional regulator
AM354_RS08220	COG0647	UMP catabolic process
AM354_RS08225	COG3469	chitinase activity
AM354_RS08230	COG0367	asparagine synthase
AM354_RS08265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM354_RS08270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM354_RS08275	COG2824	Alkylphosphonate utilization operon protein PhnA
AM354_RS08280	COG1702	phosphate starvation-inducible protein PhoH
AM354_RS08285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM354_RS08290	COG4535	Mg2 and Co2 transporter CorC
AM354_RS08295	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM354_RS08305	COG0765	amino acid transport
AM354_RS08310	COG0765	amino acid transport
AM354_RS08315	COG1126	abc transporter atp-binding protein
AM354_RS08330	COG2888	peptidyl-tyrosine sulfation
AM354_RS08335	COG0495	leucyl-tRNA aminoacylation
AM354_RS08340	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AM354_RS08345	COG1466	dna polymerase III delta subunit
AM354_RS08350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM354_RS08355	COG0799	negative regulation of ribosome biogenesis
AM354_RS08360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AM354_RS08365	COG0768	penicillin binding
AM354_RS08370	COG0772	Belongs to the SEDS family
AM354_RS08375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM354_RS08380	COG1686	Belongs to the peptidase S11 family
AM354_RS08390	COG0321	lipoyl(octanoyl) transferase activity
AM354_RS08395	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM354_RS08405	COG3706	GGDEF domain
AM354_RS08410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM354_RS08415	COG1309	transcriptional regulator
AM354_RS08420	COG2814	Major facilitator Superfamily
AM354_RS08430	COG1473	amidohydrolase
AM354_RS08435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM354_RS08450	COG0765	amino acid transport
AM354_RS08455	COG1126	abc transporter atp-binding protein
AM354_RS08465	COG1278	Cold shock
AM354_RS08470	COG2199	diguanylate cyclase activity
AM354_RS08480	COG0583	DNA-binding transcription factor activity
AM354_RS08485	COG0667	Aldo Keto reductase
AM354_RS08495	COG0604	alcohol dehydrogenase
AM354_RS08530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM354_RS08535	COG2501	S4 domain
AM354_RS08540	COG0215	cysteine-tRNA ligase activity
AM354_RS08545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM354_RS08550	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM354_RS08555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM354_RS08560	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM354_RS08570	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM354_RS08575	COG4181	ATPase activity
AM354_RS08580	COG2755	lipolytic protein G-D-S-L family
AM354_RS08585	COG0300	oxidoreductase activity
AM354_RS08590	COG3118	belongs to the thioredoxin family
AM354_RS08595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM354_RS08600	COG0549	Belongs to the carbamate kinase family
AM354_RS08610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM354_RS08615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM354_RS08620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM354_RS08625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM354_RS08635	COG3257	ureidoglycine aminohydrolase activity
AM354_RS08640	COG1929	Belongs to the glycerate kinase type-1 family
AM354_RS08645	COG2271	Major facilitator Superfamily
AM354_RS08650	COG2084	Dehydrogenase
AM354_RS08655	COG3622	Belongs to the hyi family
AM354_RS08660	COG3960	tartronate-semialdehyde synthase activity
AM354_RS08675	COG0583	DNA-binding transcription factor activity
AM354_RS08680	COG0330	HflC and HflK could
AM354_RS08685	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM354_RS08690	COG0789	Transcriptional regulator
AM354_RS08695	COG2217	Heavy metal translocating P-type atpase
AM354_RS08700	COG3735	TraB family
AM354_RS08705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM354_RS08710	COG2027	D-alanyl-D-alanine carboxypeptidase
AM354_RS08735	COG3483	tryptophan 2,3-dioxygenase activity
AM354_RS08745	COG2814	Major facilitator Superfamily
AM354_RS08755	COG0737	Belongs to the 5'-nucleotidase family
AM354_RS08760	COG2223	nitrite transmembrane transporter activity
AM354_RS08765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM354_RS08765	COG4651	solute:proton antiporter activity
AM354_RS08770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM354_RS08775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM354_RS08780	COG1929	Belongs to the glycerate kinase type-1 family
AM354_RS08785	COG2610	gluconate transmembrane transporter activity
AM354_RS08790	COG3835	regulator
AM354_RS08795	COG0563	adenylate kinase activity
AM354_RS08800	COG0326	Molecular chaperone. Has ATPase activity
AM354_RS08805	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM354_RS08815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM354_RS08820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM354_RS08825	COG2832	Protein of unknown function (DUF454)
AM354_RS08840	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM354_RS08845	COG1309	transcriptional regulator
AM354_RS08850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS08855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM354_RS08860	COG0254	rRNA binding
AM354_RS08865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM354_RS08870	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM354_RS08875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM354_RS08880	COG1121	(ABC) transporter
AM354_RS08905	COG3397	chitin binding
AM354_RS08960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM354_RS08995	COG3695	enzyme binding
AM354_RS09000	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM354_RS09005	COG1946	Acyl-CoA thioesterase
AM354_RS09010	COG0004	ammonium transporteR
AM354_RS09015	COG0347	Belongs to the P(II) protein family
AM354_RS09020	COG1132	(ABC) transporter
AM354_RS09025	COG1132	(ABC) transporter
AM354_RS09030	COG1522	sequence-specific DNA binding
AM354_RS09040	COG0561	phosphatase activity
AM354_RS09045	COG4533	DNA binding
AM354_RS09050	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM354_RS09055	COG0824	Thioesterase
AM354_RS09060	COG1555	photosystem II stabilization
AM354_RS09065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM354_RS09075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM354_RS09080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM354_RS09090	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM354_RS09095	COG0271	Belongs to the BolA IbaG family
AM354_RS09100	COG3056	Lipoprotein
AM354_RS09105	COG2223	nitrite transmembrane transporter activity
AM354_RS09110	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM354_RS09115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM354_RS09120	COG1845	cytochrome c oxidase, subunit III
AM354_RS09125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM354_RS09130	COG0109	protoheme IX farnesyltransferase activity
AM354_RS09135	COG2814	Major facilitator Superfamily
AM354_RS09140	COG1666	GTP binding
AM354_RS09145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM354_RS09150	COG0693	protein deglycase activity
AM354_RS09155	COG2831	hemolysin activation secretion protein
AM354_RS09160	COG3210	domain, Protein
AM354_RS09165	COG0301	tRNA thio-modification
AM354_RS09165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM354_RS09170	COG1722	exodeoxyribonuclease VII activity
AM354_RS09175	COG0142	geranyltranstransferase activity
AM354_RS09180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM354_RS09185	COG0667	Aldo Keto reductase
AM354_RS09190	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM354_RS09195	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM354_RS09200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM354_RS09205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM354_RS09210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM354_RS09210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM354_RS09215	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM354_RS09220	COG4238	major outer membrane lipoprotein
AM354_RS09225	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM354_RS09235	COG1862	Preprotein translocase
AM354_RS09240	COG0343	queuine tRNA-ribosyltransferase activity
AM354_RS09245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM354_RS09250	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AM354_RS09255	COG0450	alkyl hydroperoxide reductase
AM354_RS09265	COG0366	Alpha amylase catalytic
AM354_RS09270	COG0668	transmembrane transport
AM354_RS09285	COG3093	addiction module antidote protein HigA
AM354_RS09305	COG5002	protein histidine kinase activity
AM354_RS09310	COG0745	RESPONSE REGULATOR receiver
AM354_RS09315	COG0420	3'-5' exonuclease activity
AM354_RS09320	COG0419	ATPase involved in DNA repair
AM354_RS09340	COG1940	carbohydrate kinase activity
AM354_RS09345	COG2974	May be involved in recombination
AM354_RS09350	COG3123	guanosine phosphorylase activity
AM354_RS09355	COG4126	flavin adenine dinucleotide binding
AM354_RS09405	COG1595	DNA-templated transcription, initiation
AM354_RS09425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM354_RS09470	COG2226	methyltransferase
AM354_RS09480	COG3416	Protein conserved in bacteria
AM354_RS09485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM354_RS09495	COG3011	Protein conserved in bacteria
AM354_RS09505	COG1335	isochorismatase
AM354_RS09520	COG0346	lactoylglutathione lyase activity
AM354_RS09525	COG1349	DNA-binding transcription factor activity
AM354_RS09555	COG3961	Belongs to the TPP enzyme family
AM354_RS09575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM354_RS09575	COG2169	Transcriptional regulator
AM354_RS09585	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS09590	COG2207	Transcriptional regulator
AM354_RS09595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM354_RS09610	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM354_RS09615	COG1733	regulation of RNA biosynthetic process
AM354_RS09620	COG0747	negative chemotaxis
AM354_RS09625	COG3038	cytochrome b561
AM354_RS09655	COG2314	TM2 domain
AM354_RS09660	COG0583	DNA-binding transcription factor activity
AM354_RS09675	COG0702	epimerase
AM354_RS09685	COG0656	L-ascorbic acid biosynthetic process
AM354_RS09710	COG5002	protein histidine kinase activity
AM354_RS09725	COG2814	Major facilitator Superfamily
AM354_RS09740	COG2801	Transposase and inactivated derivatives
AM354_RS09755	COG2801	Transposase and inactivated derivatives
AM354_RS09775	COG1073	alpha beta
AM354_RS09780	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AM354_RS09785	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM354_RS09790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM354_RS09810	COG2991	Protein conserved in bacteria
AM354_RS09815	COG1477	protein flavinylation
AM354_RS09820	COG2871	sodium ion transport
AM354_RS09825	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM354_RS09830	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM354_RS09835	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM354_RS09840	COG1805	sodium ion transport
AM354_RS09845	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM354_RS09850	COG3034	peptidoglycan biosynthetic process
AM354_RS09855	COG0121	glutamine amidotransferase
AM354_RS09860	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM354_RS09865	COG1960	acyl-CoA dehydrogenase activity
AM354_RS09875	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AM354_RS09880	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AM354_RS09885	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AM354_RS09890	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AM354_RS09895	COG0235	Class ii aldolase
AM354_RS09900	COG0436	Aminotransferase
AM354_RS09915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM354_RS09940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM354_RS09945	COG0328	RNA-DNA hybrid ribonuclease activity
AM354_RS09950	COG2226	methyltransferase
AM354_RS09955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM354_RS09960	COG1388	LysM domain
AM354_RS09960	COG0741	lytic transglycosylase activity
AM354_RS09965	COG3021	interspecies interaction between organisms
AM354_RS09970	COG0583	DNA-binding transcription factor activity
AM354_RS09975	COG0656	L-ascorbic acid biosynthetic process
AM354_RS10010	COG0542	response to heat
AM354_RS10020	COG0564	pseudouridine synthase activity
AM354_RS10030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM354_RS10035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM354_RS10045	COG0077	Prephenate dehydratase
AM354_RS10045	COG1605	Chorismate mutase
AM354_RS10050	COG1605	Chorismate mutase
AM354_RS10050	COG0287	Prephenate dehydrogenase
AM354_RS10055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM354_RS10060	COG3137	Salt-induced outer membrane protein
AM354_RS10080	COG0335	large ribosomal subunit rRNA binding
AM354_RS10090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM354_RS10095	COG0228	four-way junction DNA binding
AM354_RS10100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM354_RS10105	COG4137	Cytochrome C assembly protein
AM354_RS10110	COG4536	flavin adenine dinucleotide binding
AM354_RS10120	COG2918	glutathione biosynthetic process
AM354_RS10125	COG1238	metal cluster binding
AM354_RS10130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM354_RS10160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM354_RS10165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM354_RS10170	COG2137	regulation of response to DNA damage stimulus
AM354_RS10195	COG1917	Cupin 2, conserved barrel domain protein
AM354_RS10195	COG2169	Transcriptional regulator
AM354_RS10200	COG2723	6-phospho-beta-galactosidase activity
AM354_RS10205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM354_RS10210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM354_RS10225	COG0667	Aldo Keto reductase
AM354_RS10240	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM354_RS10245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM354_RS10250	COG4942	peptidase
AM354_RS10250	COG1388	LysM domain
AM354_RS10255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM354_RS10260	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM354_RS10265	COG0585	pseudouridine synthase activity
AM354_RS10270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM354_RS10275	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM354_RS10280	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AM354_RS10290	COG0765	amino acid transport
AM354_RS10310	COG2895	sulfate adenylyltransferase (ATP) activity
AM354_RS10315	COG0175	sulfate reduction
AM354_RS10320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM354_RS10320	COG1648	precorrin-2 dehydrogenase activity
AM354_RS10325	COG2234	aminopeptidase activity
AM354_RS10330	COG0175	sulfate reduction
AM354_RS10335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM354_RS10340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM354_RS10345	COG0720	synthase
AM354_RS10350	COG0602	queuosine metabolic process
AM354_RS10355	COG2271	Major facilitator Superfamily
AM354_RS10360	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AM354_RS10365	COG2986	histidine ammonia-lyase
AM354_RS10395	COG0504	CTP synthase activity
AM354_RS10400	COG3956	TIGRFAM MazG family protein
AM354_RS10405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM354_RS10410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM354_RS10420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM354_RS10425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AM354_RS10430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM354_RS10440	COG2860	membrane
AM354_RS10450	COG0316	Belongs to the HesB IscA family
AM354_RS10460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM354_RS10465	COG3725	Membrane protein required for beta-lactamase induction
AM354_RS10470	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM354_RS10480	COG4969	Belongs to the N-Me-Phe pilin family
AM354_RS10485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM354_RS10490	COG1459	type II secretion system
AM354_RS10495	COG0516	GMP reductase activity
AM354_RS10505	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AM354_RS10510	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM354_RS10515	COG0494	nUDIX hydrolase
AM354_RS10520	COG0653	protein targeting
AM354_RS10540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM354_RS10545	COG0849	cell division
AM354_RS10550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM354_RS10560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM354_RS10565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM354_RS10570	COG0772	Belongs to the SEDS family
AM354_RS10580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM354_RS10585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM354_RS10590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM354_RS10595	COG0768	penicillin binding
AM354_RS10600	COG3116	cell division
AM354_RS10605	COG0275	rRNA processing
AM354_RS10610	COG2001	Belongs to the MraZ family
AM354_RS10630	COG0028	Belongs to the TPP enzyme family
AM354_RS10635	COG1022	Amp-dependent synthetase and ligase
AM354_RS10640	COG0583	DNA-binding transcription factor activity
AM354_RS10645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM354_RS10650	COG0473	3-isopropylmalate dehydrogenase activity
AM354_RS10655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM354_RS10660	COG0066	3-isopropylmalate dehydratase activity
AM354_RS10665	COG0471	metal ion transport
AM354_RS10670	COG2814	Major facilitator Superfamily
AM354_RS10685	COG4143	(ABC) transporter
AM354_RS10690	COG1178	ABC-type Fe3 transport system permease component
AM354_RS10705	COG0028	Belongs to the TPP enzyme family
AM354_RS10710	COG0440	acetolactate synthase activity
AM354_RS10715	COG0586	Pfam SNARE associated Golgi protein
AM354_RS10720	COG0417	DNA replication proofreading
AM354_RS10725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM354_RS10730	COG0564	pseudouridine synthase activity
AM354_RS10740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM354_RS10750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM354_RS10755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM354_RS10760	COG2967	ApaG domain
AM354_RS10765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM354_RS10775	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM354_RS10785	COG2966	Psort location CytoplasmicMembrane, score
AM354_RS10805	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM354_RS10810	COG0505	Belongs to the CarA family
AM354_RS10815	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM354_RS10840	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AM354_RS10845	COG1047	Peptidyl-prolyl cis-trans
AM354_RS10850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM354_RS10855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM354_RS10860	COG0196	riboflavin kinase activity
AM354_RS10865	COG0268	Binds directly to 16S ribosomal RNA
AM354_RS10870	COG0583	DNA-binding transcription factor activity
AM354_RS10875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM354_RS10880	COG0484	heat shock protein binding
AM354_RS10885	COG0443	Heat shock 70 kDa protein
AM354_RS10890	COG1584	GPR1 FUN34 yaaH family protein
AM354_RS10900	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM354_RS10905	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM354_RS10910	COG1115	amino acid carrier protein
AM354_RS10915	COG3022	response to hydroperoxide
AM354_RS10945	COG0745	RESPONSE REGULATOR receiver
AM354_RS10950	COG3045	CreA protein
AM354_RS10955	COG2207	Transcriptional regulator
AM354_RS10955	COG3708	Transcriptional regulator
AM354_RS10960	COG0406	alpha-ribazole phosphatase activity
AM354_RS10965	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AM354_RS10970	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AM354_RS10975	COG0741	lytic transglycosylase activity
AM354_RS10985	COG2199	diguanylate cyclase activity
AM354_RS10990	COG2885	chlorophyll binding
AM354_RS10995	COG0488	(ABC) transporter
AM354_RS11010	COG2130	NADP-dependent
AM354_RS11020	COG0604	alcohol dehydrogenase
AM354_RS11040	COG0560	Phosphoserine phosphatase
AM354_RS11045	COG3726	membrane protein affecting hemolysin expression
AM354_RS11055	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM354_RS11065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM354_RS11070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM354_RS11075	COG0084	hydrolase, TatD family'
AM354_RS11080	COG4667	esterase of the alpha-beta hydrolase superfamily
AM354_RS11085	COG3237	CsbD-like
AM354_RS11090	COG5487	UPF0391 membrane protein
AM354_RS11095	COG2823	Periplasmic or secreted lipoprotein
AM354_RS11100	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM354_RS11110	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM354_RS11115	COG2813	Specifically methylates the guanine in position
AM354_RS11120	COG0667	Aldo Keto reductase
AM354_RS11150	COG3706	GGDEF domain
AM354_RS11155	COG1309	transcriptional regulator
AM354_RS11175	COG0738	Major facilitator superfamily
AM354_RS11180	COG3254	rhamnose metabolic process
AM354_RS11190	COG3618	amidohydrolase
AM354_RS11195	COG4948	Mandelate Racemase Muconate Lactonizing
AM354_RS11200	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM354_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS11215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM354_RS11220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM354_RS11225	COG2368	4-hydroxyphenylacetate
AM354_RS11245	COG3971	2-oxopent-4-enoate hydratase activity
AM354_RS11260	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS11275	COG1846	Transcriptional regulator
AM354_RS11280	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS11300	COG1113	amino acid transport
AM354_RS11330	COG2267	carboxylic ester hydrolase activity
AM354_RS11340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM354_RS11350	COG1454	alcohol dehydrogenase
AM354_RS11385	COG0811	peptide transport
AM354_RS11410	COG1376	ErfK ybiS ycfS ynhG family protein
AM354_RS11415	COG2207	Transcriptional regulator
AM354_RS11415	COG3708	Transcriptional regulator
AM354_RS11425	COG2207	Transcriptional regulator
AM354_RS11435	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS11440	COG2610	gluconate transmembrane transporter activity
AM354_RS11445	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM354_RS11460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM354_RS11465	COG0583	DNA-binding transcription factor activity
AM354_RS11485	COG0174	glutamine synthetase
AM354_RS11495	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM354_RS11505	COG1116	anion transmembrane transporter activity
AM354_RS11525	COG0583	DNA-binding transcription factor activity
AM354_RS11530	COG1966	Carbon starvation protein
AM354_RS11535	COG2879	small protein
AM354_RS11540	COG0523	cobalamin synthesis protein
AM354_RS11550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM354_RS11565	COG1088	dTDP-glucose 4,6-dehydratase activity
AM354_RS11570	COG1609	Transcriptional regulator
AM354_RS11575	COG1263	PTS System
AM354_RS11575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS11580	COG2723	6-phospho-beta-galactosidase activity
AM354_RS11590	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM354_RS11610	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM354_RS11615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM354_RS11625	COG1349	DNA-binding transcription factor activity
AM354_RS11630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM354_RS11635	COG2610	gluconate transmembrane transporter activity
AM354_RS11650	COG0738	Major facilitator superfamily
AM354_RS11675	COG0795	lipopolysaccharide-transporting ATPase activity
AM354_RS11680	COG0795	lipopolysaccharide-transporting ATPase activity
AM354_RS11685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM354_RS11690	COG2927	DNA polymerase III (CHI subunit)
AM354_RS11700	COG0456	acetyltransferase
AM354_RS11705	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM354_RS11720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM354_RS11730	COG0540	Belongs to the ATCase OTCase family
AM354_RS11735	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AM354_RS11750	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AM354_RS11755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM354_RS11765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS11765	COG1263	PTS System
AM354_RS11770	COG0366	Alpha amylase catalytic
AM354_RS11775	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM354_RS11780	COG0583	DNA-binding transcription factor activity
AM354_RS11810	COG0701	Predicted permease
AM354_RS11815	COG2188	Transcriptional regulator
AM354_RS11820	COG3624	Phosphonate C-P lyase system protein PhnG
AM354_RS11825	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM354_RS11830	COG3626	phosphonate metabolism
AM354_RS11835	COG3627	carbon phosphorus lyase activity
AM354_RS11840	COG4107	phosphonate C-P lyase system protein PhnK
AM354_RS11845	COG4778	phosphonate C-P lyase system protein PhnL
AM354_RS11850	COG3454	Phosphonate metabolism
AM354_RS11855	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM354_RS11865	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM354_RS11870	COG0702	epimerase
AM354_RS11875	COG3787	Belongs to the UPF0306 family
AM354_RS11885	COG1982	Orn Lys Arg decarboxylase major
AM354_RS11890	COG0531	amino acid
AM354_RS11895	COG2827	Endonuclease containing a URI domain
AM354_RS11900	COG3153	acetyltransferase
AM354_RS11905	COG3154	lipid carrier protein
AM354_RS11910	COG0826	peptidase U32
AM354_RS11915	COG0826	peptidase U32
AM354_RS11935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM354_RS11940	COG0425	Belongs to the sulfur carrier protein TusA family
AM354_RS11945	COG2391	methyltransferase activity
AM354_RS11950	COG0513	Belongs to the DEAD box helicase family
AM354_RS11965	COG1185	polyribonucleotide nucleotidyltransferase activity
AM354_RS11975	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM354_RS11980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM354_RS11985	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM354_RS11990	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM354_RS11995	COG0195	Participates in both transcription termination and antitermination
AM354_RS12000	COG0779	Required for maturation of 30S ribosomal subunits
AM354_RS12015	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM354_RS12020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM354_RS12025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM354_RS12035	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AM354_RS12040	COG1534	Rna-binding protein
AM354_RS12050	COG2027	D-alanyl-D-alanine carboxypeptidase
AM354_RS12055	COG0745	RESPONSE REGULATOR receiver
AM354_RS12060	COG0642	Histidine kinase
AM354_RS12065	COG2801	Transposase and inactivated derivatives
AM354_RS12080	COG2801	Transposase and inactivated derivatives
AM354_RS12090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM354_RS12095	COG0697	spore germination
AM354_RS12100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM354_RS12105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM354_RS12110	COG0142	geranyltranstransferase activity
AM354_RS12120	COG3423	Transcriptional regulator
AM354_RS12125	COG0039	L-malate dehydrogenase activity
AM354_RS12130	COG1438	arginine binding
AM354_RS12145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM354_RS12150	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM354_RS12160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM354_RS12165	COG2105	PFAM AIG2 family protein
AM354_RS12170	COG2911	Protein conserved in bacteria
AM354_RS12175	COG0729	surface antigen
AM354_RS12180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM354_RS12185	COG1253	flavin adenine dinucleotide binding
AM354_RS12195	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM354_RS12205	COG0737	Belongs to the 5'-nucleotidase family
AM354_RS12215	COG0545	Peptidyl-prolyl cis-trans isomerase
AM354_RS12220	COG3061	Opacity-associated protein A
AM354_RS12230	COG0359	binds to the 23S rRNA
AM354_RS12235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM354_RS12245	COG0360	Binds together with S18 to 16S ribosomal RNA
AM354_RS12260	COG1073	alpha beta
AM354_RS12265	COG3650	response to hydrogen peroxide
AM354_RS12275	COG3766	membrane
AM354_RS12280	COG1960	acyl-CoA dehydrogenase activity
AM354_RS12285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM354_RS12290	COG0557	exoribonuclease II activity
AM354_RS12295	COG1959	2 iron, 2 sulfur cluster binding
AM354_RS12300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM354_RS12305	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM354_RS12310	COG0330	HflC and HflK could
AM354_RS12315	COG0330	HflC and HflK could
AM354_RS12320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM354_RS12330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM354_RS12335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM354_RS12340	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM354_RS12345	COG0802	atpase or kinase
AM354_RS12350	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM354_RS12350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM354_RS12355	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM354_RS12375	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM354_RS12380	COG1162	GTPase activity
AM354_RS12385	COG0688	phosphatidylethanolamine metabolic process
AM354_RS12390	COG3264	Mechanosensitive ion channel
AM354_RS12390	COG1511	domain protein
AM354_RS12395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM354_RS12400	COG1053	succinate dehydrogenase
AM354_RS12405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM354_RS12410	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM354_RS12415	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM354_RS12430	COG5510	response to toxic substance
AM354_RS12435	COG5510	response to toxic substance
AM354_RS12440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM354_RS12445	COG1509	lysine 2,3-aminomutase activity
AM354_RS12455	COG0840	transmembrane signaling receptor activity
AM354_RS12465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM354_RS12480	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM354_RS12490	COG4232	protein-disulfide reductase activity
AM354_RS12495	COG1309	transcriptional regulator
AM354_RS12510	COG3647	Membrane
AM354_RS12520	COG1535	isochorismatase
AM354_RS12520	COG3433	isochorismatase activity
AM354_RS12525	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM354_RS12530	COG1169	isochorismate synthase
AM354_RS12540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM354_RS12540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM354_RS12550	COG2382	esterase
AM354_RS12555	COG4771	TonB-dependent receptor
AM354_RS12560	COG3391	amine dehydrogenase activity
AM354_RS12565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM354_RS12570	COG4774	siderophore transport
AM354_RS12570	COG1629	transport
AM354_RS12575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM354_RS12580	COG3433	isochorismatase activity
AM354_RS12580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM354_RS12580	COG2226	methyltransferase
AM354_RS12585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM354_RS12585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM354_RS12590	COG1301	dicarboxylic acid transport
AM354_RS12595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM354_RS12600	COG3162	membrane
AM354_RS12605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM354_RS12635	COG0138	bifunctional purine biosynthesis protein purh
AM354_RS12640	COG0151	Belongs to the GarS family
AM354_RS12660	COG1515	deoxyribonuclease V activity
AM354_RS12665	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM354_RS12670	COG2816	NAD+ diphosphatase activity
AM354_RS12675	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AM354_RS12680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AM354_RS12685	COG0352	thiamine-phosphate diphosphorylase activity
AM354_RS12690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM354_RS12695	COG2104	thiamine diphosphate biosynthetic process
AM354_RS12700	COG2022	thiamine diphosphate biosynthetic process
AM354_RS12720	COG5002	protein histidine kinase activity
AM354_RS12735	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM354_RS12740	COG0085	RNA polymerase activity
AM354_RS12750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM354_RS12765	COG0250	Participates in transcription elongation, termination and antitermination
AM354_RS12775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM354_RS12810	COG1072	(Pantothenic acid kinase))
AM354_RS12815	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM354_RS12815	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM354_RS12820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM354_RS12850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM354_RS12855	COG1739	Uncharacterized protein family UPF0029
AM354_RS12860	COG0006	proline dipeptidase activity
AM354_RS12865	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM354_RS12865	COG1024	Enoyl-CoA hydratase
AM354_RS12870	COG0183	Belongs to the thiolase family
AM354_RS12900	COG0084	hydrolase, TatD family'
AM354_RS12905	COG0805	protein transport
AM354_RS12915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM354_RS12920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM354_RS12925	COG3165	ubiquinone biosynthetic process from chorismate
AM354_RS12930	COG2226	methyltransferase
AM354_RS12935	COG1322	Protein conserved in bacteria
AM354_RS12940	COG0586	Pfam SNARE associated Golgi protein
AM354_RS12955	COG0412	Dienelactone hydrolase
AM354_RS12960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM354_RS12970	COG0697	spore germination
AM354_RS12985	COG0584	glycerophosphoryl diester phosphodiesterase
AM354_RS12990	COG3842	ATPase activity
AM354_RS13000	COG1175	transmembrane transport
AM354_RS13005	COG1653	transport
AM354_RS13010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM354_RS13025	COG4177	L-phenylalanine transmembrane transporter activity
AM354_RS13030	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM354_RS13040	COG0456	acetyltransferase
AM354_RS13060	COG2177	Part of the ABC transporter FtsEX involved in
AM354_RS13065	COG2884	Cell division ATP-binding protein ftsE
AM354_RS13070	COG0552	protein localization to endoplasmic reticulum
AM354_RS13070	COG0552	protein localization to endoplasmic reticulum
AM354_RS13075	COG0742	ribosomal rna small subunit methyltransferase
AM354_RS13080	COG3776	membrane
AM354_RS13090	COG3714	YhhN family
AM354_RS13105	COG2217	Heavy metal translocating P-type atpase
AM354_RS13120	COG0425	Belongs to the sulfur carrier protein TusA family
AM354_RS13125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM354_RS13140	COG0247	lactate metabolic process
AM354_RS13150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM354_RS13160	COG2271	Major facilitator Superfamily
AM354_RS13165	COG0584	glycerophosphoryl diester phosphodiesterase
AM354_RS13170	COG0561	phosphatase activity
AM354_RS13175	COG2267	carboxylic ester hydrolase activity
AM354_RS13180	COG1280	lysine exporter protein (LysE YggA)
AM354_RS13185	COG1280	lysine exporter protein (LysE YggA)
AM354_RS13190	COG0514	ATP-dependent DNA helicase (RecQ)
AM354_RS13200	COG2050	protein possibly involved in aromatic compounds catabolism
AM354_RS13225	COG0210	DNA helicase
AM354_RS13230	COG1011	Hydrolase
AM354_RS13240	COG3159	Protein conserved in bacteria
AM354_RS13245	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM354_RS13250	COG5567	small periplasmic lipoprotein
AM354_RS13255	COG1965	Belongs to the frataxin family
AM354_RS13260	COG3072	Adenylate cyclase
AM354_RS13265	COG0181	hydroxymethylbilane synthase activity
AM354_RS13275	COG2959	enzyme of heme biosynthesis
AM354_RS13280	COG3071	HemY protein
AM354_RS13310	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM354_RS13320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM354_RS13325	COG2244	polysaccharide biosynthetic process
AM354_RS13330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM354_RS13335	COG0456	acetyltransferase
AM354_RS13340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM354_RS13345	COG1088	dTDP-glucose 4,6-dehydratase activity
AM354_RS13350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM354_RS13355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM354_RS13365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM354_RS13370	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM354_RS13375	COG3118	belongs to the thioredoxin family
AM354_RS13385	COG0248	Ppx GppA phosphatase
AM354_RS13395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM354_RS13400	COG0612	Peptidase, M16
AM354_RS13405	COG1301	dicarboxylic acid transport
AM354_RS13410	COG2200	EAL domain
AM354_RS13410	COG2199	diguanylate cyclase activity
AM354_RS13415	COG0457	Tetratricopeptide repeat
AM354_RS13415	COG3118	belongs to the thioredoxin family
AM354_RS13420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM354_RS13425	COG1215	transferase activity, transferring glycosyl groups
AM354_RS13455	COG2194	sulfuric ester hydrolase activity
AM354_RS13460	COG4608	Belongs to the ABC transporter superfamily
AM354_RS13465	COG0444	Belongs to the ABC transporter superfamily
AM354_RS13470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM354_RS13475	COG0601	transmembrane transport
AM354_RS13480	COG0747	negative chemotaxis
AM354_RS13500	COG2271	Major facilitator Superfamily
AM354_RS13510	COG2197	response regulator
AM354_RS13515	COG2194	sulfuric ester hydrolase activity
AM354_RS13520	COG1764	response to oxidative stress
AM354_RS13525	COG1846	Transcriptional regulator
AM354_RS13555	COG2814	Major facilitator Superfamily
AM354_RS13570	COG2807	transmembrane transport
AM354_RS13575	COG0583	DNA-binding transcription factor activity
AM354_RS13590	COG0402	S-adenosylhomocysteine deaminase activity
AM354_RS13595	COG1335	isochorismatase
AM354_RS13605	COG3274	enterobacterial common antigen metabolic process
AM354_RS13620	COG0583	DNA-binding transcription factor activity
AM354_RS13635	COG3276	selenocysteine insertion sequence binding
AM354_RS13640	COG1921	L-seryl-tRNASec selenium transferase activity
AM354_RS13645	COG0625	glutathione transferase activity
AM354_RS13655	COG3058	Necessary for formate dehydrogenase activity
AM354_RS13660	COG2864	formate dehydrogenase
AM354_RS13665	COG0437	4 iron, 4 sulfur cluster binding
AM354_RS13675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM354_RS13680	COG0840	transmembrane signaling receptor activity
AM354_RS13685	COG2258	MOSC domain
AM354_RS13700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM354_RS13710	COG3722	fumarate hydratase activity
AM354_RS13715	COG0246	Mannitol dehydrogenase
AM354_RS13720	COG2213	PTS system mannitol-specific
AM354_RS13720	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS13735	COG0751	glycine-tRNA ligase activity
AM354_RS13740	COG0752	glycyl-tRNA synthetase alpha subunit
AM354_RS13750	COG2818	Glycosylase
AM354_RS13760	COG2885	chlorophyll binding
AM354_RS13765	COG1609	Transcriptional regulator
AM354_RS13775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM354_RS13780	COG2814	Major facilitator Superfamily
AM354_RS13785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM354_RS13790	COG0366	Alpha amylase catalytic
AM354_RS13795	COG3977	Valine--pyruvate aminotransferase
AM354_RS13810	COG2985	domain, Protein
AM354_RS13815	COG0071	Belongs to the small heat shock protein (HSP20) family
AM354_RS13820	COG0071	Belongs to the small heat shock protein (HSP20) family
AM354_RS13825	COG5645	(Lipo)protein
AM354_RS13830	COG0823	Involved in the tonB-independent uptake of proteins
AM354_RS13840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM354_RS13845	COG2423	ornithine cyclodeaminase activity
AM354_RS13850	COG0561	phosphatase activity
AM354_RS13855	COG0187	DNA topoisomerase II activity
AM354_RS13860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM354_RS13865	COG0592	DNA-directed DNA polymerase activity
AM354_RS13870	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM354_RS13880	COG0594	ribonuclease P activity
AM354_RS13885	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM354_RS13890	COG0706	membrane insertase activity
AM354_RS13895	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM354_RS13905	COG2091	lysine biosynthetic process via aminoadipic acid
AM354_RS13910	COG0431	NADPH-dependent FMN reductase
AM354_RS13920	COG2252	PERMEase
AM354_RS13925	COG0494	nUDIX hydrolase
AM354_RS13930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM354_RS13935	COG0765	amino acid transport
AM354_RS13940	COG0765	amino acid transport
AM354_RS13945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM354_RS13950	COG0704	Plays a role in the regulation of phosphate uptake
AM354_RS13960	COG0581	inorganic phosphate transmembrane transporter activity
AM354_RS13965	COG0573	inorganic phosphate transmembrane transporter activity
AM354_RS13970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM354_RS13980	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM354_RS13985	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM354_RS13990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM354_RS13995	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM354_RS14000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM354_RS14005	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM354_RS14010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM354_RS14025	COG3312	ion transport
AM354_RS14030	COG0357	Ribosomal RNA small subunit methyltransferase G
AM354_RS14035	COG0445	tRNA wobble uridine modification
AM354_RS14040	COG0716	FMN binding
AM354_RS14045	COG1522	sequence-specific DNA binding
AM354_RS14050	COG2502	aspartate--ammonia ligase
AM354_RS14055	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM354_RS14060	COG0714	Associated with various cellular activities
AM354_RS14065	COG3158	transport of potassium into the cell
AM354_RS14070	COG1869	D-ribose catabolic process
AM354_RS14075	COG1129	ABC transporter
AM354_RS14080	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS14090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM354_RS14095	COG1609	Transcriptional regulator
AM354_RS14100	COG0477	Major facilitator Superfamily
AM354_RS14105	COG2186	Transcriptional regulator
AM354_RS14130	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM354_RS14135	COG0746	molybdenum cofactor guanylyltransferase activity
AM354_RS14140	COG3084	Protein conserved in bacteria
AM354_RS14145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM354_RS14150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM354_RS14155	COG0204	Acyl-transferase
AM354_RS14160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM354_RS14160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM354_RS14165	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AM354_RS14175	COG3078	GTPase activator activity
AM354_RS14185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM354_RS14195	COG3852	Histidine kinase
AM354_RS14205	COG1217	gtp-binding protein TYPA
AM354_RS14210	COG1011	Hydrolase
AM354_RS14215	COG1295	ribonuclease BN
AM354_RS14220	COG1490	D-aminoacyl-tRNA deacylase activity
AM354_RS14225	COG0456	acetyltransferase
AM354_RS14230	COG2982	Protein involved in outer membrane biogenesis
AM354_RS14235	COG2233	PERMEase
AM354_RS14240	COG0786	glutamate:sodium symporter activity
AM354_RS14245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM354_RS14250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM354_RS14255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM354_RS14260	COG1758	RNA polymerase activity
AM354_RS14265	COG0194	GDP metabolic process
AM354_RS14270	COG2860	membrane
AM354_RS14280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM354_RS14290	COG1561	YicC-like family, N-terminal region
AM354_RS14295	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM354_RS14300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM354_RS14305	COG1309	transcriptional regulator
AM354_RS14310	COG0756	dUTP diphosphatase activity
AM354_RS14315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM354_RS14320	COG2003	Belongs to the UPF0758 family
AM354_RS14325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM354_RS14330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM354_RS14350	COG1519	Transferase
AM354_RS14360	COG0438	transferase activity, transferring glycosyl groups
AM354_RS14370	COG0859	PFAM glycosyl transferase family 9
AM354_RS14385	COG1442	glycosyl transferase family 8
AM354_RS14385	COG1216	Glycosyl transferase, family 2
AM354_RS14390	COG3307	-O-antigen
AM354_RS14395	COG0438	transferase activity, transferring glycosyl groups
AM354_RS14400	COG0859	PFAM glycosyl transferase family 9
AM354_RS14405	COG0859	PFAM glycosyl transferase family 9
AM354_RS14410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM354_RS14415	COG0156	8-amino-7-oxononanoate synthase activity
AM354_RS14420	COG1063	alcohol dehydrogenase
AM354_RS14425	COG2861	carbohydrate metabolic process
AM354_RS14430	COG4942	peptidase
AM354_RS14435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM354_RS14440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM354_RS14445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM354_RS14460	COG1045	serine acetyltransferase
AM354_RS14475	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM354_RS14480	COG2205	protein histidine kinase activity
AM354_RS14485	COG0745	RESPONSE REGULATOR receiver
AM354_RS14490	COG3678	ATP-independent chaperone mediated protein folding
AM354_RS14495	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM354_RS14500	COG0205	6-phosphofructokinase activity
AM354_RS14505	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM354_RS14510	COG0149	triose-phosphate isomerase activity
AM354_RS14520	COG3152	Membrane
AM354_RS14535	COG2814	Major facilitator Superfamily
AM354_RS14540	COG1494	fructose-1,6-bisphosphatase
AM354_RS14555	COG3074	FtsZ-dependent cytokinesis
AM354_RS14560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM354_RS14565	COG1575	Belongs to the MenA family. Type 1 subfamily
AM354_RS14570	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AM354_RS14575	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AM354_RS14580	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM354_RS14585	COG1609	Transcriptional regulator
AM354_RS14590	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM354_RS14595	COG0254	rRNA binding
AM354_RS14600	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AM354_RS14605	COG0626	cystathionine gamma-synthase activity
AM354_RS14610	COG0460	homoserine dehydrogenase
AM354_RS14610	COG0527	aspartate kinase activity
AM354_RS14620	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AM354_RS14635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM354_RS14640	COG0137	argininosuccinate synthase activity
AM354_RS14645	COG0165	Argininosuccinate lyase
AM354_RS14655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM354_RS14660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM354_RS14660	COG0678	peroxiredoxin activity
AM354_RS14670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM354_RS14685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM354_RS14690	COG4206	TonB-dependent receptor
AM354_RS14695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM354_RS14735	COG0583	DNA-binding transcription factor activity
AM354_RS14740	COG3085	chromosome segregation
AM354_RS14750	COG2814	Major facilitator Superfamily
AM354_RS14765	COG3978	acetolactate synthase activity
AM354_RS14770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM354_RS14775	COG0129	dihydroxy-acid dehydratase activity
AM354_RS14780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM354_RS14805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM354_RS14810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM354_RS14815	COG2200	EAL domain
AM354_RS14820	COG2982	Protein involved in outer membrane biogenesis
AM354_RS14825	COG2134	cdp-diacylglycerol pyrophosphatase
AM354_RS14830	COG0477	Major facilitator Superfamily
AM354_RS14835	COG1295	ribonuclease BN
AM354_RS14840	COG1024	Enoyl-CoA hydratase
AM354_RS14845	COG5001	Diguanylate cyclase
AM354_RS14850	COG3678	ATP-independent chaperone mediated protein folding
AM354_RS14855	COG5441	Belongs to the UPF0261 family
AM354_RS14880	COG2205	protein histidine kinase activity
AM354_RS14880	COG0784	Response regulator, receiver
AM354_RS14890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM354_RS14895	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM354_RS14905	COG0339	signal peptide processing
AM354_RS14910	COG0742	ribosomal rna small subunit methyltransferase
AM354_RS14925	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS14930	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS14935	COG1129	ABC transporter
AM354_RS14950	COG0589	response to stress
AM354_RS14955	COG0583	DNA-binding transcription factor activity
AM354_RS14970	COG0306	phosphate transporter
AM354_RS14975	COG2081	HI0933 family
AM354_RS14980	COG0346	lactoylglutathione lyase activity
AM354_RS15005	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM354_RS15015	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM354_RS15025	COG3299	homolog of phage Mu protein gp47
AM354_RS15035	COG4384	Bacteriophage Mu Gp45 protein
AM354_RS15055	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
AM354_RS15065	COG4386	tail sheath protein
AM354_RS15095	COG4397	Mu-like prophage major head subunit gpT
AM354_RS15115	COG4373	Mu-like prophage FluMu protein gp28
AM354_RS15205	COG2842	Transposition protein
AM354_RS15210	COG2801	Transposase and inactivated derivatives
AM354_RS15215	COG3423	Transcriptional regulator
AM354_RS15230	COG0697	spore germination
AM354_RS15245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM354_RS15270	COG2130	NADP-dependent
AM354_RS15280	COG2197	response regulator
AM354_RS15305	COG3188	usher protein
AM354_RS15325	COG4619	ABC transporter
AM354_RS15330	COG0390	transport system, permease component
AM354_RS15340	COG0477	Major facilitator Superfamily
AM354_RS15340	COG2814	Major facilitator Superfamily
AM354_RS15350	COG3718	enzyme involved in inositol metabolism
AM354_RS15360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM354_RS15365	COG3962	Belongs to the TPP enzyme family
AM354_RS15370	COG0673	inositol 2-dehydrogenase activity
AM354_RS15375	COG1082	Xylose isomerase domain protein TIM barrel
AM354_RS15380	COG1082	Xylose isomerase domain protein TIM barrel
AM354_RS15385	COG3191	aminopeptidase activity
AM354_RS15390	COG1247	-acetyltransferase
AM354_RS15395	COG1741	Belongs to the pirin family
AM354_RS15420	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AM354_RS15425	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM354_RS15430	COG3457	Alanine racemase
AM354_RS15440	COG2188	Transcriptional regulator
AM354_RS15445	COG1609	Transcriptional regulator
AM354_RS15450	COG2610	gluconate transmembrane transporter activity
AM354_RS15455	COG3265	gluconokinase activity
AM354_RS15460	COG2095	MarC family integral membrane protein
AM354_RS15465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM354_RS15470	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AM354_RS15475	COG1523	belongs to the glycosyl hydrolase 13 family
AM354_RS15480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM354_RS15485	COG0297	glycogen (starch) synthase activity
AM354_RS15490	COG0058	SHG alpha-glucan phosphorylase activity
AM354_RS15495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM354_RS15500	COG1349	DNA-binding transcription factor activity
AM354_RS15505	COG0705	Rhomboid family
AM354_RS15510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM354_RS15555	COG2909	trisaccharide binding
AM354_RS15560	COG0058	SHG alpha-glucan phosphorylase activity
AM354_RS15565	COG1640	4-alpha-glucanotransferase
AM354_RS15570	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM354_RS15570	COG0316	Belongs to the HesB IscA family
AM354_RS15575	COG1040	competence protein
AM354_RS15600	COG1918	ferrous iron import across plasma membrane
AM354_RS15605	COG2183	response to ionizing radiation
AM354_RS15610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM354_RS15615	COG0484	heat shock protein binding
AM354_RS15650	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM354_RS15655	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM354_RS15660	COG1011	Hydrolase
AM354_RS15670	COG0494	nUDIX hydrolase
AM354_RS15675	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM354_RS15700	COG4796	Type ii and iii secretion system protein
AM354_RS15705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM354_RS15710	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM354_RS15730	COG0546	phosphoglycolate phosphatase activity
AM354_RS15735	COG0180	Tryptophanyl-tRNA synthetase
AM354_RS15740	COG1648	precorrin-2 dehydrogenase activity
AM354_RS15740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM354_RS15745	COG2116	formate transmembrane transporter activity
AM354_RS15755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM354_RS15760	COG0402	S-adenosylhomocysteine deaminase activity
AM354_RS15775	COG0738	Major facilitator superfamily
AM354_RS15780	COG1609	Transcriptional regulator
AM354_RS15785	COG1486	melibiose metabolic process
AM354_RS15790	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM354_RS15800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM354_RS15805	COG3275	phosphorelay sensor kinase activity
AM354_RS15825	COG0433	COG0433 Predicted ATPase
AM354_RS15840	COG1289	transmembrane transporter activity
AM354_RS15845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM354_RS15850	COG1765	OsmC-like protein
AM354_RS15855	COG3954	Phosphoribulokinase
AM354_RS15860	COG3089	Belongs to the UPF0270 family
AM354_RS15865	COG0429	hydrolase of the alpha beta-hydrolase fold
AM354_RS15880	COG4521	taurine ABC transporter
AM354_RS15890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM354_RS15895	COG2175	clavaminate synthase activity
AM354_RS15900	COG0488	(ABC) transporter
AM354_RS15905	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM354_RS15915	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM354_RS15920	COG1047	Peptidyl-prolyl cis-trans
AM354_RS15925	COG1609	Transcriptional regulator
AM354_RS15930	COG1757	Na H antiporter
AM354_RS15935	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM354_RS15940	COG2900	Belongs to the SlyX family
AM354_RS15945	COG0545	Peptidyl-prolyl cis-trans isomerase
AM354_RS15950	COG2964	Protein conserved in bacteria
AM354_RS15955	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM354_RS15960	COG2923	Belongs to the DsrF TusC family
AM354_RS15965	COG2168	tRNA wobble position uridine thiolation
AM354_RS15970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM354_RS15975	COG0049	tRNA binding
AM354_RS15985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM354_RS16000	COG0051	transcription antitermination factor activity, RNA binding
AM354_RS16005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM354_RS16010	COG0088	Forms part of the polypeptide exit tunnel
AM354_RS16015	COG0089	rRNA binding
AM354_RS16025	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM354_RS16035	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AM354_RS16040	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM354_RS16080	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM354_RS16085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM354_RS16090	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM354_RS16095	COG1841	ribosomal large subunit assembly
AM354_RS16105	COG0201	protein transport
AM354_RS16110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM354_RS16115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM354_RS16120	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM354_RS16125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM354_RS16130	COG0202	RNA polymerase activity
AM354_RS16135	COG0203	ribosomal protein L17
AM354_RS16145	COG0789	Transcriptional regulator
AM354_RS16150	COG3036	rescue of stalled ribosome
AM354_RS16155	COG1970	mechanosensitive ion channel activity
AM354_RS16160	COG0569	domain protein
AM354_RS16165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM354_RS16165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM354_RS16170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM354_RS16175	COG0242	peptide deformylase activity
AM354_RS16180	COG0758	DNA mediated transformation
AM354_RS16185	COG2922	Belongs to the Smg family
AM354_RS16190	COG0551	DNA topoisomerase type I activity
AM354_RS16195	COG0009	L-threonylcarbamoyladenylate synthase
AM354_RS16200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM354_RS16205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM354_RS16240	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AM354_RS16245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM354_RS16255	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AM354_RS16260	COG0800	Aldolase
AM354_RS16265	COG0129	dihydroxy-acid dehydratase activity
AM354_RS16270	COG2610	gluconate transmembrane transporter activity
AM354_RS16275	COG3265	gluconokinase activity
AM354_RS16280	COG1414	Transcriptional regulator
AM354_RS16285	COG1410	methionine synthase
AM354_RS16285	COG0646	methionine synthase
AM354_RS16290	COG2801	Transposase and inactivated derivatives
AM354_RS16305	COG2801	Transposase and inactivated derivatives
AM354_RS16315	COG2188	Transcriptional regulator
AM354_RS16330	COG0395	ABC-type sugar transport system, permease component
AM354_RS16340	COG3842	ATPase activity
AM354_RS16345	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM354_RS16365	COG0527	aspartate kinase activity
AM354_RS16375	COG0166	Belongs to the GPI family
AM354_RS16385	COG3223	Belongs to the PsiE family
AM354_RS16390	COG3833	ABC-type maltose transport systems, permease component
AM354_RS16395	COG1175	transmembrane transport
AM354_RS16400	COG2182	Extracellular solute-binding protein
AM354_RS16405	COG0366	Alpha amylase catalytic
AM354_RS16415	COG4580	involved in the transport of maltose and maltodextrins
AM354_RS16430	COG1609	Transcriptional regulator
AM354_RS16435	COG0477	Major facilitator Superfamily
AM354_RS16440	COG3161	chorismate lyase activity
AM354_RS16445	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM354_RS16450	COG2937	Belongs to the GPAT DAPAT family
AM354_RS16455	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM354_RS16460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM354_RS16465	COG0534	Mate efflux family protein
AM354_RS16470	COG3237	CsbD-like
AM354_RS16475	COG0735	belongs to the Fur family
AM354_RS16485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM354_RS16495	COG0604	alcohol dehydrogenase
AM354_RS16515	COG1522	sequence-specific DNA binding
AM354_RS16520	COG1448	Aminotransferase
AM354_RS16525	COG0432	Pfam Uncharacterised protein family UPF0047
AM354_RS16530	COG2315	Protein conserved in bacteria
AM354_RS16535	COG0110	maltose O-acetyltransferase activity
AM354_RS16540	COG1064	alcohol dehydrogenase
AM354_RS16545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM354_RS16560	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS16575	COG0625	glutathione transferase activity
AM354_RS16585	COG2252	PERMEase
AM354_RS16590	COG0025	NhaP-type Na H and K H
AM354_RS16595	COG0583	DNA-binding transcription factor activity
AM354_RS16600	COG1380	Effector of murein hydrolase LrgA
AM354_RS16615	COG0504	CTP synthase activity
AM354_RS16620	COG1560	Kdo2-lipid A biosynthetic process
AM354_RS16645	COG2264	protein methyltransferase activity
AM354_RS16650	COG4145	pantothenate transmembrane transporter activity
AM354_RS16655	COG3924	membrane
AM354_RS16660	COG0439	Biotin carboxylase
AM354_RS16665	COG0511	ligase activity, forming carbon-carbon bonds
AM354_RS16670	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM354_RS16675	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AM354_RS16680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM354_RS16685	COG0604	alcohol dehydrogenase
AM354_RS16690	COG2200	EAL domain
AM354_RS16690	COG2199	diguanylate cyclase activity
AM354_RS16695	COG1077	Cell shape determining protein MreB Mrl
AM354_RS16700	COG1792	Involved in formation and maintenance of cell shape
AM354_RS16705	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM354_RS16710	COG0424	maF-like protein
AM354_RS16715	COG1530	ribonuclease E activity
AM354_RS16720	COG3164	Protein of unknown function
AM354_RS16725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM354_RS16730	COG0312	modulator of DNA gyrase
AM354_RS16735	COG2134	cdp-diacylglycerol pyrophosphatase
AM354_RS16760	COG0583	DNA-binding transcription factor activity
AM354_RS16770	COG1566	PFAM secretion protein HlyD family protein
AM354_RS16775	COG1289	transmembrane transporter activity
AM354_RS16785	COG2732	(Barnase) inhibitor
AM354_RS16790	COG3028	Belongs to the UPF0307 family
AM354_RS16795	COG0312	modulator of DNA gyrase
AM354_RS16800	COG3783	Cytochrome b(562)
AM354_RS16805	COG2207	Transcriptional regulator
AM354_RS16815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM354_RS16825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM354_RS16855	COG3964	amidohydrolase
AM354_RS16875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS16875	COG3711	transcriptional antiterminator
AM354_RS16880	COG5499	transcription regulator containing HTH domain
AM354_RS16885	COG4680	protein conserved in bacteria
AM354_RS16890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS16895	COG1660	Displays ATPase and GTPase activities
AM354_RS16910	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM354_RS16915	COG1137	ATPase activity
AM354_RS16920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM354_RS16925	COG3117	lipopolysaccharide transmembrane transporter activity
AM354_RS16930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM354_RS16935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM354_RS16935	COG0517	IMP dehydrogenase activity
AM354_RS16940	COG0530	calcium, potassium:sodium antiporter activity
AM354_RS16945	COG1127	ABC transporter
AM354_RS16950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM354_RS16955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM354_RS16960	COG2854	intermembrane phospholipid transfer
AM354_RS16965	COG3113	response to antibiotic
AM354_RS16970	COG5007	Belongs to the BolA IbaG family
AM354_RS16975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM354_RS16980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM354_RS16985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM354_RS16990	COG3105	Protein conserved in bacteria
AM354_RS16995	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM354_RS17000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM354_RS17005	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM354_RS17015	COG0625	glutathione transferase activity
AM354_RS17020	COG2969	positive regulation of protein catabolic process
AM354_RS17030	COG0493	'glutamate synthase
AM354_RS17035	COG0069	glutamate synthase activity
AM354_RS17035	COG0070	glutamate synthase
AM354_RS17035	COG0067	glutamate synthase
AM354_RS17045	COG1242	4 iron, 4 sulfur cluster binding
AM354_RS17055	COG5002	protein histidine kinase activity
AM354_RS17055	COG0784	Response regulator, receiver
AM354_RS17055	COG2198	Histidine kinase
AM354_RS17060	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM354_RS17065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM354_RS17070	COG2823	Periplasmic or secreted lipoprotein
AM354_RS17075	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM354_RS17080	COG0792	nuclease activity
AM354_RS17085	COG3107	peptidoglycan biosynthetic process
AM354_RS17090	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM354_RS17100	COG1741	Belongs to the pirin family
AM354_RS17105	COG0583	DNA-binding transcription factor activity
AM354_RS17110	COG0435	Glutathione S-transferase
AM354_RS17115	COG2259	Doxx family
AM354_RS17125	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM354_RS17130	COG4575	ribosome binding
AM354_RS17140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM354_RS17145	COG0586	Pfam SNARE associated Golgi protein
AM354_RS17160	COG2271	Major facilitator Superfamily
AM354_RS17165	COG1904	glucuronate isomerase
AM354_RS17170	COG2721	sulfolactate sulfo-lyase activity
AM354_RS17175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AM354_RS17180	COG0861	Integral membrane protein TerC family
AM354_RS17185	COG0519	Catalyzes the synthesis of GMP from XMP
AM354_RS17185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM354_RS17190	COG0673	inositol 2-dehydrogenase activity
AM354_RS17195	COG1451	nucleotide metabolic process
AM354_RS17200	COG2813	Specifically methylates the guanine in position
AM354_RS17205	COG1902	pentaerythritol trinitrate reductase activity
AM354_RS17205	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM354_RS17210	COG0488	(ABC) transporter
AM354_RS17220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM354_RS17225	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS17235	COG0625	glutathione transferase activity
AM354_RS17265	COG0358	DNA primase activity
AM354_RS17270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM354_RS17275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM354_RS17280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AM354_RS17285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM354_RS17290	COG1968	undecaprenyl-diphosphatase activity
AM354_RS17295	COG0617	tRNA 3'-terminal CCA addition
AM354_RS17300	COG4991	sh3 domain protein
AM354_RS17305	COG3025	triphosphatase activity
AM354_RS17310	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM354_RS17315	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AM354_RS17315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AM354_RS17325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM354_RS17335	COG3384	dioxygenase
AM354_RS17340	COG0754	glutathionylspermidine amidase activity
AM354_RS17345	COG5463	Belongs to the UPF0441 family
AM354_RS17355	COG2376	Dihydroxyacetone kinase
AM354_RS17360	COG1461	Dihydroxyacetone kinase
AM354_RS17365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS17365	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AM354_RS17365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM354_RS17375	COG1538	Outer membrane efflux protein
AM354_RS17380	COG0494	nUDIX hydrolase
AM354_RS17385	COG3151	Protein conserved in bacteria
AM354_RS17390	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM354_RS17395	COG3150	esterase
AM354_RS17400	COG0187	DNA topoisomerase II activity
AM354_RS17405	COG0583	DNA-binding transcription factor activity
AM354_RS17410	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM354_RS17415	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM354_RS17420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM354_RS17430	COG2132	Multicopper oxidase
AM354_RS17435	COG0583	DNA-binding transcription factor activity
AM354_RS17440	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM354_RS17445	COG2211	Major facilitator Superfamily
AM354_RS17450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM354_RS17500	COG0640	Transcriptional regulator
AM354_RS17505	COG1902	pentaerythritol trinitrate reductase activity
AM354_RS17510	COG0583	DNA-binding transcription factor activity
AM354_RS17520	COG1234	tRNA 3'-trailer cleavage
AM354_RS17565	COG0110	maltose O-acetyltransferase activity
AM354_RS17570	COG2223	nitrite transmembrane transporter activity
AM354_RS17580	COG1609	Transcriptional regulator
AM354_RS17615	COG0431	NADPH-dependent FMN reductase
AM354_RS17620	COG0640	Transcriptional regulator
AM354_RS17660	COG3436	PFAM IS66 Orf2 family protein
AM354_RS17665	COG1120	ATPase activity
AM354_RS17670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS17675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS17680	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AM354_RS17685	COG4772	TonB-dependent receptor
AM354_RS17690	COG3712	iron ion homeostasis
AM354_RS17695	COG1595	DNA-templated transcription, initiation
AM354_RS17715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM354_RS17740	COG0431	NADPH-dependent FMN reductase
AM354_RS17770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM354_RS17830	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS17860	COG0739	heme binding
AM354_RS17870	COG2132	Multicopper oxidase
AM354_RS17875	COG3667	copper resistance
AM354_RS17880	COG2372	response to copper ion
AM354_RS17885	COG1276	copper resistance
AM354_RS17890	COG0745	RESPONSE REGULATOR receiver
AM354_RS17895	COG2205	protein histidine kinase activity
AM354_RS17910	COG3436	PFAM IS66 Orf2 family protein
AM354_RS17995	COG0741	lytic transglycosylase activity
AM354_RS18000	COG0656	L-ascorbic acid biosynthetic process
AM354_RS18005	COG1979	alcohol dehydrogenase
AM354_RS18010	COG2207	Transcriptional regulator
AM354_RS18015	COG0586	Pfam SNARE associated Golgi protein
AM354_RS18030	COG0848	biopolymer transport protein
AM354_RS18060	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM354_RS18065	COG1473	amidohydrolase
AM354_RS18070	COG1473	amidohydrolase
AM354_RS18075	COG0583	DNA-binding transcription factor activity
AM354_RS18080	COG4772	TonB-dependent receptor
AM354_RS18120	COG0454	-acetyltransferase
AM354_RS18125	COG2819	hydrolase of the alpha beta superfamily
AM354_RS18165	COG3188	usher protein
AM354_RS18170	COG3121	Chaperone
AM354_RS18175	COG3539	Fimbrial protein
AM354_RS18250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM354_RS18275	COG0789	Transcriptional regulator
AM354_RS18285	COG0629	single-stranded DNA binding
AM354_RS18445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM354_RS18450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM354_RS18510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM354_RS18520	COG0789	Transcriptional regulator
AM354_RS18610	COG0431	NADPH-dependent FMN reductase
AM354_RS18615	COG1393	Belongs to the ArsC family
AM354_RS18620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM354_RS18630	COG0659	secondary active sulfate transmembrane transporter activity
AM354_RS18635	COG0589	response to stress
AM354_RS18645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM354_RS18775	COG0210	DNA helicase
AM354_RS18785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM354_RS18795	COG1982	Orn Lys Arg decarboxylase major
AM354_RS18800	COG0741	lytic transglycosylase activity
AM354_RS18805	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AM354_RS18815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM354_RS18820	COG3171	Protein conserved in bacteria
AM354_RS18825	COG2066	Belongs to the glutaminase family
AM354_RS18840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM354_RS18850	COG1872	DUF167
AM354_RS18855	COG0762	integral membrane protein
AM354_RS18860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM354_RS18865	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM354_RS18870	COG2805	Type II/IV secretion system protein
AM354_RS18875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM354_RS18880	COG1678	Uncharacterized ACR, COG1678
AM354_RS18885	COG0189	ligase activity
AM354_RS18890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM354_RS18895	COG2356	endonuclease I
AM354_RS18900	COG3091	SprT-like family
AM354_RS18910	COG3708	Transcriptional regulator
AM354_RS18910	COG2207	Transcriptional regulator
AM354_RS18915	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM354_RS18925	COG2010	Cytochrome c
AM354_RS18925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM354_RS18935	COG2010	Cytochrome c
AM354_RS18935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM354_RS18940	COG1113	amino acid transport
AM354_RS18945	COG2186	Transcriptional regulator
AM354_RS18950	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM354_RS18955	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM354_RS18960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM354_RS18970	COG3112	Uncharacterised protein family (UPF0231)
AM354_RS18975	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AM354_RS18980	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AM354_RS18990	COG2132	Multicopper oxidase
AM354_RS19000	COG0288	reversible hydration of carbon dioxide
AM354_RS19005	COG1131	(ABC) transporter
AM354_RS19010	COG0842	Transport permease protein
AM354_RS19015	COG0726	polysaccharide deacetylase
AM354_RS19020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM354_RS19025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM354_RS19030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM354_RS19040	COG0642	Histidine kinase
AM354_RS19045	COG2149	membrane
AM354_RS19055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM354_RS19060	COG0617	tRNA 3'-terminal CCA addition
AM354_RS19065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM354_RS19080	COG1489	DNA binding
AM354_RS19085	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM354_RS19090	COG1643	Atp-dependent helicase
AM354_RS19095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM354_RS19100	COG4774	siderophore transport
AM354_RS19105	COG1120	ATPase activity
AM354_RS19110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM354_RS19115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS19130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM354_RS19135	COG1166	arginine decarboxylase activity
AM354_RS19140	COG0010	Belongs to the arginase family
AM354_RS19150	COG2271	Major facilitator Superfamily
AM354_RS19155	COG2146	nitrite reductase [NAD(P)H] activity
AM354_RS19170	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS19175	COG1414	Transcriptional regulator
AM354_RS19200	COG2267	carboxylic ester hydrolase activity
AM354_RS19205	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS19210	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AM354_RS19225	COG0501	Belongs to the peptidase M48B family
AM354_RS19230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM354_RS19235	COG1114	Component of the transport system for branched-chain amino acids
AM354_RS19255	COG3842	ATPase activity
AM354_RS19260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM354_RS19270	COG4638	Rieske (2fe-2S)
AM354_RS19275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM354_RS19280	COG0473	3-isopropylmalate dehydrogenase activity
AM354_RS19285	COG0583	DNA-binding transcription factor activity
AM354_RS19290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM354_RS19295	COG0126	phosphoglycerate kinase activity
AM354_RS19300	COG0191	fructose-bisphosphate aldolase activity
AM354_RS19315	COG2271	Major facilitator Superfamily
AM354_RS19330	COG3122	Protein conserved in bacteria
AM354_RS19340	COG0235	Class ii aldolase
AM354_RS19345	COG3623	hexulose-6-phosphate isomerase
AM354_RS19350	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AM354_RS19355	COG1070	Carbohydrate kinase
AM354_RS19365	COG2731	YhcH YjgK YiaL family protein
AM354_RS19385	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS19390	COG1129	ABC transporter
AM354_RS19395	COG1414	Transcriptional regulator
AM354_RS19400	COG1279	arginine transmembrane transporter activity
AM354_RS19410	COG0583	DNA-binding transcription factor activity
AM354_RS19420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM354_RS19425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM354_RS19435	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AM354_RS19440	COG3079	Belongs to the UPF0149 family
AM354_RS19445	COG0006	proline dipeptidase activity
AM354_RS19450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM354_RS19455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM354_RS19460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM354_RS19465	COG0509	glycine decarboxylation via glycine cleavage system
AM354_RS19470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM354_RS19470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM354_RS19500	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS19540	COG1349	DNA-binding transcription factor activity
AM354_RS19550	COG1129	ABC transporter
AM354_RS19555	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS19565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM354_RS19570	COG1940	carbohydrate kinase activity
AM354_RS19575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM354_RS19585	COG1272	protein, Hemolysin III
AM354_RS19595	COG0354	folic acid binding
AM354_RS19600	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM354_RS19610	COG0745	RESPONSE REGULATOR receiver
AM354_RS19615	COG2205	protein histidine kinase activity
AM354_RS19620	COG4452	Inner membrane protein CreD
AM354_RS19625	COG0716	FMN binding
AM354_RS19630	COG4974	Belongs to the 'phage' integrase family
AM354_RS19635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM354_RS19640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM354_RS19650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM354_RS19660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM354_RS19670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM354_RS19685	COG3247	response to pH
AM354_RS19690	COG0583	DNA-binding transcription factor activity
AM354_RS19695	COG1335	isochorismatase
AM354_RS19700	COG4942	peptidase
AM354_RS19705	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM354_RS19710	COG5265	(ABC) transporter
AM354_RS19715	COG1309	transcriptional regulator
AM354_RS19720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM354_RS19730	COG2814	Major facilitator Superfamily
AM354_RS19740	COG1304	FMN binding
AM354_RS19745	COG1620	l-lactate permease
AM354_RS19775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS19790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM354_RS19800	COG0582	viral genome integration into host DNA
AM354_RS19810	COG3121	Chaperone
AM354_RS19825	COG3539	Fimbrial protein
AM354_RS19830	COG2197	response regulator
AM354_RS19835	COG2197	response regulator
AM354_RS19840	COG0582	viral genome integration into host DNA
AM354_RS19845	COG4615	Cyclic peptide transporter
AM354_RS19855	COG2807	transmembrane transport
AM354_RS19860	COG1349	DNA-binding transcription factor activity
AM354_RS19870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS19875	COG3715	PTS system
AM354_RS19880	COG3716	PTS system mannose fructose sorbose family IID component
AM354_RS19890	COG4178	(ABC) transporter
AM354_RS19910	COG0583	DNA-binding transcription factor activity
AM354_RS19915	COG0583	DNA-binding transcription factor activity
AM354_RS19935	COG1609	Transcriptional regulator
AM354_RS19950	COG0318	PFAM AMP-dependent synthetase and ligase
AM354_RS19950	COG0204	Acyl-transferase
AM354_RS19955	COG0477	Major facilitator Superfamily
AM354_RS19960	COG0667	Aldo Keto reductase
AM354_RS19970	COG0861	Integral membrane protein TerC family
AM354_RS19975	COG3066	DNA modification
AM354_RS19980	COG0494	nUDIX hydrolase
AM354_RS19990	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM354_RS19995	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM354_RS20000	COG2165	general secretion pathway protein
AM354_RS20020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM354_RS20025	COG1025	Belongs to the peptidase M16 family
AM354_RS20030	COG1074	ATP-dependent DNA helicase activity
AM354_RS20035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM354_RS20040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM354_RS20040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM354_RS20045	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM354_RS20065	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM354_RS20070	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM354_RS20075	COG2166	iron-sulfur cluster assembly
AM354_RS20080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM354_RS20090	COG0583	DNA-binding transcription factor activity
AM354_RS20095	COG2363	Small membrane protein
AM354_RS20100	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AM354_RS20105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM354_RS20110	COG1611	Belongs to the LOG family
AM354_RS20125	COG2814	Major facilitator Superfamily
AM354_RS20130	COG3098	single-species biofilm formation
AM354_RS20135	COG2373	Large extracellular alpha-helical protein
AM354_RS20140	COG4953	penicillin-binding protein 1C
AM354_RS20145	COG0564	pseudouridine synthase activity
AM354_RS20165	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM354_RS20175	COG0052	Belongs to the universal ribosomal protein uS2 family
AM354_RS20185	COG0528	UMP kinase activity
AM354_RS20190	COG0233	cytoplasmic translational termination
AM354_RS20195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM354_RS20205	COG0575	Belongs to the CDS family
AM354_RS20210	COG0750	zinc metalloprotease
AM354_RS20215	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM354_RS20220	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM354_RS20225	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM354_RS20230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM354_RS20235	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM354_RS20240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM354_RS20245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM354_RS20250	COG0587	DNA-directed DNA polymerase activity
AM354_RS20255	COG0825	malonyl-CoA metabolic process
AM354_RS20260	COG1982	Orn Lys Arg decarboxylase major
AM354_RS20270	COG0346	lactoylglutathione lyase activity
AM354_RS20275	COG3710	Transcriptional regulator
AM354_RS20280	COG0531	amino acid
AM354_RS20290	COG3104	oligopeptide transport
AM354_RS20295	COG0037	tRNA processing
AM354_RS20305	COG4568	rho-dependent transcription termination
AM354_RS20320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM354_RS20325	COG3015	lipoprotein NlpE involved in copper resistance
AM354_RS20330	COG0442	prolyl-tRNA aminoacylation
AM354_RS20335	COG1720	tRNA m6t6A37 methyltransferase activity
AM354_RS20345	COG1464	Belongs to the NlpA lipoprotein family
AM354_RS20350	COG2011	ABC-type metal ion transport system permease component
AM354_RS20360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM354_RS20385	COG0477	Major facilitator Superfamily
AM354_RS20390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM354_RS20395	COG1042	CoA-binding domain protein
AM354_RS20395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM354_RS20395	COG0045	succinate-CoA ligase (ADP-forming) activity
AM354_RS20400	COG3148	PFAM DTW domain containing protein
AM354_RS20405	COG3118	belongs to the thioredoxin family
AM354_RS20410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM354_RS20415	COG2814	Major facilitator Superfamily
AM354_RS20420	COG1566	PFAM secretion protein HlyD family protein
AM354_RS20430	COG1846	Transcriptional regulator
AM354_RS20440	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM354_RS20445	COG2814	Major facilitator Superfamily
AM354_RS20450	COG0583	DNA-binding transcription factor activity
AM354_RS20455	COG2113	Glycine betaine
AM354_RS20460	COG4176	ABC-type proline glycine betaine transport system permease component
AM354_RS20480	COG3493	citrate carrier protein
AM354_RS20485	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM354_RS20490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM354_RS20495	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS20515	COG1780	Probably involved in ribonucleotide reductase function
AM354_RS20520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM354_RS20525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM354_RS20535	COG4575	ribosome binding
AM354_RS20550	COG0477	Major facilitator Superfamily
AM354_RS20560	COG0477	Major facilitator Superfamily
AM354_RS20580	COG2840	Smr protein MutS2
AM354_RS20585	COG2259	Doxx family
AM354_RS20590	COG3592	Divergent 4Fe-4S mono-cluster
AM354_RS20595	COG2388	GCN5-related N-acetyl-transferase
AM354_RS20630	COG0641	radical SAM
AM354_RS20640	COG2149	membrane
AM354_RS20645	COG2188	Transcriptional regulator
AM354_RS20665	COG3182	Iron-regulated membrane protein
AM354_RS20670	COG0583	DNA-binding transcription factor activity
AM354_RS20685	COG1566	PFAM secretion protein HlyD family protein
AM354_RS20700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM354_RS20705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS20715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM354_RS20725	COG1309	transcriptional regulator
AM354_RS20785	COG4695	Portal protein
AM354_RS20930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM354_RS20935	COG2867	negative regulation of translational initiation
AM354_RS20940	COG2914	Belongs to the UPF0125 (RnfH) family
AM354_RS20945	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM354_RS20950	COG0497	DNA recombination
AM354_RS20955	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM354_RS20960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM354_RS20965	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM354_RS20985	COG0513	Belongs to the DEAD box helicase family
AM354_RS20990	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM354_RS20995	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM354_RS21010	COG3026	antisigma factor binding
AM354_RS21015	COG3086	response to oxidative stress
AM354_RS21025	COG0481	GTPase activity
AM354_RS21035	COG0571	ribonuclease III activity
AM354_RS21040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM354_RS21045	COG1381	Involved in DNA repair and RecF pathway recombination
AM354_RS21050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM354_RS21055	COG0736	holo-[acyl-carrier-protein] synthase activity
AM354_RS21060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM354_RS21065	COG1737	Transcriptional regulator
AM354_RS21070	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM354_RS21075	COG1263	PTS System
AM354_RS21075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS21080	COG0560	Phosphoserine phosphatase
AM354_RS21095	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM354_RS21105	COG2205	protein histidine kinase activity
AM354_RS21110	COG3170	Tfp pilus assembly protein FimV
AM354_RS21115	COG2204	response regulator
AM354_RS21120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM354_RS21120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM354_RS21125	COG0347	Belongs to the P(II) protein family
AM354_RS21140	COG0583	DNA-binding transcription factor activity
AM354_RS21150	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM354_RS21155	COG3842	ATPase activity
AM354_RS21160	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM354_RS21165	COG1177	transmembrane transport
AM354_RS21170	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS21175	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AM354_RS21185	COG1017	nitric oxide dioxygenase activity
AM354_RS21185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM354_RS21190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM354_RS21195	COG2814	Major facilitator Superfamily
AM354_RS21200	COG3711	transcriptional antiterminator
AM354_RS21205	COG3683	transport system, periplasmic component
AM354_RS21210	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM354_RS21225	COG1959	2 iron, 2 sulfur cluster binding
AM354_RS21230	COG1104	cysteine desulfurase activity
AM354_RS21235	COG0822	iron-sulfur transferase activity
AM354_RS21240	COG0316	Belongs to the HesB IscA family
AM354_RS21245	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM354_RS21250	COG0443	Heat shock 70 kDa protein
AM354_RS21255	COG0633	Ferredoxin
AM354_RS21260	COG2975	iron-sulfur cluster assembly
AM354_RS21265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM354_RS21275	COG0105	UTP biosynthetic process
AM354_RS21280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM354_RS21290	COG1426	Protein conserved in bacteria
AM354_RS21295	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM354_RS21300	COG0124	histidyl-tRNA synthetase
AM354_RS21305	COG2976	Protein conserved in bacteria
AM354_RS21310	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM354_RS21315	COG1160	GTP binding
AM354_RS21325	COG1645	bacterial-type flagellum-dependent swarming motility
AM354_RS21340	COG1609	Transcriptional regulator
AM354_RS21345	COG2271	Major facilitator Superfamily
AM354_RS21355	COG1570	exodeoxyribonuclease VII activity
AM354_RS21365	COG0517	IMP dehydrogenase activity
AM354_RS21365	COG0516	GMP reductase activity
AM354_RS21370	COG0519	Catalyzes the synthesis of GMP from XMP
AM354_RS21370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM354_RS21375	COG0582	viral genome integration into host DNA
AM354_RS21395	COG3723	Recombinational DNA repair protein, rece pathway
AM354_RS21410	COG1475	DNA binding
AM354_RS21590	COG3646	Phage regulatory protein
AM354_RS21630	COG1733	regulation of RNA biosynthetic process
AM354_RS21640	COG5002	protein histidine kinase activity
AM354_RS21640	COG2205	protein histidine kinase activity
AM354_RS21640	COG0784	Response regulator, receiver
AM354_RS21660	COG1187	pseudouridine synthase activity
AM354_RS21685	COG2814	Major facilitator Superfamily
AM354_RS21700	COG1289	transmembrane transporter activity
AM354_RS21720	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AM354_RS21725	COG0351	phosphomethylpyrimidine kinase
AM354_RS21740	COG1349	DNA-binding transcription factor activity
AM354_RS21745	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS21750	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS21765	COG3730	PTS system glucitol sorbitol-specific
AM354_RS21775	COG1830	Aldolase
AM354_RS21780	COG1597	lipid kinase activity
AM354_RS21785	COG0826	peptidase U32
AM354_RS21790	COG3422	double-strand break repair
AM354_RS21805	COG0745	RESPONSE REGULATOR receiver
AM354_RS21810	COG2205	protein histidine kinase activity
AM354_RS21815	COG2814	Major facilitator Superfamily
AM354_RS21820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM354_RS21825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM354_RS21830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM354_RS21835	COG0667	Aldo Keto reductase
AM354_RS21850	COG0443	Heat shock 70 kDa protein
AM354_RS21865	COG5001	Diguanylate cyclase
AM354_RS21865	COG3447	MASE1 domain protein
AM354_RS21865	COG5002	protein histidine kinase activity
AM354_RS21870	COG2239	Acts as a magnesium transporter
AM354_RS21885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM354_RS21890	COG0573	inorganic phosphate transmembrane transporter activity
AM354_RS21895	COG0573	inorganic phosphate transmembrane transporter activity
AM354_RS21915	COG2831	hemolysin activation secretion protein
AM354_RS21920	COG3210	domain, Protein
AM354_RS21945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM354_RS21950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM354_RS21955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM354_RS21960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM354_RS21965	COG2233	PERMEase
AM354_RS21975	COG2261	transglycosylase associated protein
AM354_RS21985	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM354_RS22000	COG1393	Belongs to the ArsC family
AM354_RS22005	COG4783	chaperone-mediated protein folding
AM354_RS22050	COG0628	permease
AM354_RS22055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM354_RS22060	COG2716	regulation of RNA biosynthetic process
AM354_RS22065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM354_RS22070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM354_RS22075	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM354_RS22080	COG2321	neutral zinc metallopeptidase
AM354_RS22085	COG1444	tRNA N-acetyltransferase activity
AM354_RS22090	COG0400	carboxylic ester hydrolase activity
AM354_RS22100	COG1876	peptidase activity
AM354_RS22105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM354_RS22110	COG1393	Belongs to the ArsC family
AM354_RS22130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM354_RS22140	COG2197	response regulator
AM354_RS22145	COG3850	Histidine kinase
AM354_RS22155	COG0494	nUDIX hydrolase
AM354_RS22160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM354_RS22165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM354_RS22170	COG3397	chitin binding
AM354_RS22175	COG0583	DNA-binding transcription factor activity
AM354_RS22215	COG2040	homocysteine
AM354_RS22220	COG0833	amino acid
AM354_RS22235	COG1770	oligopeptidase
AM354_RS22245	COG1671	Belongs to the UPF0178 family
AM354_RS22250	COG0408	coproporphyrinogen oxidase activity
AM354_RS22255	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM354_RS22260	COG0456	acetyltransferase
AM354_RS22265	COG3111	PFAM Bacterial OB fold (BOF) protein
AM354_RS22280	COG2837	iron assimilation
AM354_RS22290	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM354_RS22295	COG4208	sulfate ABC transporter
AM354_RS22310	COG0745	RESPONSE REGULATOR receiver
AM354_RS22315	COG2205	protein histidine kinase activity
AM354_RS22325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM354_RS22330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS22340	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AM354_RS22345	COG3115	cell septum assembly
AM354_RS22355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM354_RS22360	COG3530	Putative quorum-sensing-regulated virulence factor
AM354_RS22365	COG0385	Bile acid
AM354_RS22370	COG0583	DNA-binding transcription factor activity
AM354_RS22385	COG4303	Ethanolamine ammonia lyase large subunit
AM354_RS22390	COG4302	ethanolamine ammonia-lyase activity
AM354_RS22410	COG0747	negative chemotaxis
AM354_RS22415	COG4774	siderophore transport
AM354_RS22420	COG2382	esterase
AM354_RS22425	COG1120	ATPase activity
AM354_RS22430	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS22435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS22440	COG4592	Periplasmic binding protein
AM354_RS22470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM354_RS22475	COG2116	formate transmembrane transporter activity
AM354_RS22500	COG3188	usher protein
AM354_RS22505	COG3121	Chaperone
AM354_RS22520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM354_RS22525	COG1914	H( )-stimulated, divalent metal cation uptake system
AM354_RS22535	COG0667	Aldo Keto reductase
AM354_RS22540	COG3961	Belongs to the TPP enzyme family
AM354_RS22555	COG1794	racemase activity, acting on amino acids and derivatives
AM354_RS22570	COG2223	nitrite transmembrane transporter activity
AM354_RS22580	COG3279	Response regulator of the LytR AlgR family
AM354_RS22585	COG3275	phosphorelay sensor kinase activity
AM354_RS22600	COG0436	Aminotransferase
AM354_RS22605	COG3038	cytochrome b561
AM354_RS22615	COG1598	PFAM Uncharacterised protein family UPF0150
AM354_RS22620	COG0457	Tetratricopeptide repeat
AM354_RS22625	COG0726	polysaccharide deacetylase
AM354_RS22625	COG1649	PFAM Uncharacterised BCR, COG1649
AM354_RS22630	COG1215	transferase activity, transferring glycosyl groups
AM354_RS22645	COG2951	lytic endotransglycosylase activity
AM354_RS22665	COG0583	DNA-binding transcription factor activity
AM354_RS22675	COG2197	response regulator
AM354_RS22690	COG3708	Transcriptional regulator
AM354_RS22690	COG2207	Transcriptional regulator
AM354_RS22695	COG2706	6-phosphogluconolactonase activity
AM354_RS22705	COG2116	formate transmembrane transporter activity
AM354_RS22715	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM354_RS22720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM354_RS22725	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM354_RS22730	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AM354_RS22735	COG1138	Cytochrome C-type biogenesis protein
AM354_RS22740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM354_RS22745	COG4235	cytochrome complex assembly
AM354_RS22745	COG3088	subunit of a heme lyase
AM354_RS22750	COG3088	subunit of a heme lyase
AM354_RS22750	COG4235	cytochrome complex assembly
AM354_RS22765	COG3691	Protein conserved in bacteria
AM354_RS22770	COG0183	Belongs to the thiolase family
AM354_RS22775	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM354_RS22775	COG1024	Enoyl-CoA hydratase
AM354_RS22780	COG2062	phosphohistidine phosphatase, SixA
AM354_RS22785	COG2840	Smr protein MutS2
AM354_RS22790	COG2890	protein-(glutamine-N5) methyltransferase activity
AM354_RS22795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM354_RS22805	COG0730	response to heat
AM354_RS22810	COG3101	peptidyl-lysine hydroxylation
AM354_RS22820	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM354_RS22820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM354_RS22825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM354_RS22840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM354_RS22845	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM354_RS22885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM354_RS22890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM354_RS22930	COG0642	Histidine kinase
AM354_RS22935	COG0697	spore germination
AM354_RS22945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM354_RS22950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM354_RS22960	COG0586	Pfam SNARE associated Golgi protein
AM354_RS22965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM354_RS22970	COG0285	dihydrofolate synthase activity
AM354_RS22975	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM354_RS22980	COG1286	toxin biosynthetic process
AM354_RS22985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM354_RS22990	COG0163	prenyltransferase activity
AM354_RS22995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM354_RS23000	COG4215	(ABC) transporter
AM354_RS23010	COG4598	ABC transporter
AM354_RS23015	COG1090	epimerase
AM354_RS23020	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM354_RS23025	COG0625	glutathione transferase activity
AM354_RS23030	COG0622	Phosphoesterase
AM354_RS23035	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM354_RS23040	COG1609	Transcriptional regulator
AM354_RS23045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS23055	COG3037	sugar-specific permease SgaT UlaA
AM354_RS23060	COG3959	Transketolase, thiamine diphosphate binding domain
AM354_RS23065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM354_RS23080	COG0857	belongs to the CobB CobQ family
AM354_RS23080	COG0280	phosphate acetyltransferase
AM354_RS23085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM354_RS23090	COG3092	negative regulation of chromosome organization
AM354_RS23095	COG3013	Belongs to the UPF0304 family
AM354_RS23100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM354_RS23105	COG0490	domain, Protein
AM354_RS23105	COG0471	metal ion transport
AM354_RS23110	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM354_RS23115	COG0436	Aminotransferase
AM354_RS23120	COG0583	DNA-binding transcription factor activity
AM354_RS23125	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM354_RS23130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM354_RS23135	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM354_RS23135	COG0649	NAD binding
AM354_RS23150	COG1034	ATP synthesis coupled electron transport
AM354_RS23155	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM354_RS23165	COG0839	Belongs to the complex I subunit 6 family
AM354_RS23170	COG0713	ATP synthesis coupled electron transport
AM354_RS23175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM354_RS23180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM354_RS23185	COG1007	ATP synthesis coupled electron transport
AM354_RS23190	COG0583	DNA-binding transcription factor activity
AM354_RS23205	COG1609	Transcriptional regulator
AM354_RS23210	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS23215	COG1063	alcohol dehydrogenase
AM354_RS23220	COG4575	ribosome binding
AM354_RS23225	COG3459	Glycosyltransferase 36 associated
AM354_RS23230	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AM354_RS23235	COG0596	Alpha beta hydrolase
AM354_RS23240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM354_RS23250	COG0318	PFAM AMP-dependent synthetase and ligase
AM354_RS23265	COG0814	amino acid
AM354_RS23290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM354_RS23300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM354_RS23305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM354_RS23315	COG2205	protein histidine kinase activity
AM354_RS23315	COG0784	Response regulator, receiver
AM354_RS23320	COG2197	response regulator
AM354_RS23325	COG2198	Histidine kinase
AM354_RS23325	COG0642	Histidine kinase
AM354_RS23330	COG2223	nitrite transmembrane transporter activity
AM354_RS23345	COG0346	lactoylglutathione lyase activity
AM354_RS23360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM354_RS23500	COG3083	sulfuric ester hydrolase activity
AM354_RS23505	COG3082	Protein of unknown function (DUF1414)
AM354_RS23510	COG3081	Nucleoid-associated protein
AM354_RS23515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AM354_RS23520	COG1061	Type III restriction enzyme res subunit
AM354_RS23525	COG1187	pseudouridine synthase activity
AM354_RS23530	COG2814	Major facilitator Superfamily
AM354_RS23540	COG4172	Belongs to the ABC transporter superfamily
AM354_RS23545	COG4239	(ABC) transporter, permease
AM354_RS23550	COG4174	ABC transporter (Permease)
AM354_RS23555	COG4166	transmembrane transport
AM354_RS23560	COG2200	EAL domain
AM354_RS23565	COG0791	NLP P60 protein
AM354_RS23575	COG0671	phosphoesterase, PA-phosphatase related
AM354_RS23580	COG0523	cobalamin synthesis protein
AM354_RS23590	COG0246	Mannitol dehydrogenase
AM354_RS23595	COG1312	Catalyzes the dehydration of D-mannonate
AM354_RS23600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM354_RS23620	COG0243	molybdopterin cofactor binding
AM354_RS23625	COG3005	denitrification pathway
AM354_RS23630	COG0494	nUDIX hydrolase
AM354_RS23640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS23640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS23645	COG1105	Belongs to the carbohydrate kinase PfkB family
AM354_RS23650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM354_RS23650	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM354_RS23650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM354_RS23655	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AM354_RS23660	COG2855	membrane
AM354_RS23670	COG0583	DNA-binding transcription factor activity
AM354_RS23675	COG0833	amino acid
AM354_RS23685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS23700	COG4771	TonB-dependent receptor
AM354_RS23705	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS23710	COG1129	ABC transporter
AM354_RS23715	COG1396	sequence-specific DNA binding
AM354_RS23715	COG1917	Cupin 2, conserved barrel domain protein
AM354_RS23720	COG0174	glutamine synthetase
AM354_RS23730	COG0531	amino acid
AM354_RS23735	COG2925	Exonuclease
AM354_RS23760	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM354_RS23765	COG1289	transmembrane transporter activity
AM354_RS23770	COG2926	Belongs to the UPF0265 family
AM354_RS23775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM354_RS23780	COG1473	amidohydrolase
AM354_RS23790	COG1063	alcohol dehydrogenase
AM354_RS23795	COG1879	ABC-type sugar transport system periplasmic component
AM354_RS23805	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM354_RS23810	COG1070	Carbohydrate kinase
AM354_RS23815	COG3623	hexulose-6-phosphate isomerase
AM354_RS23825	COG1609	Transcriptional regulator
AM354_RS23845	COG0583	DNA-binding transcription factor activity
AM354_RS23875	COG0795	lipopolysaccharide-transporting ATPase activity
AM354_RS23880	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM354_RS23890	COG2244	polysaccharide biosynthetic process
AM354_RS23895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM354_RS23900	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM354_RS23905	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM354_RS23910	COG0156	8-amino-7-oxononanoate synthase activity
AM354_RS23915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM354_RS23930	COG0456	acetyltransferase
AM354_RS23940	COG0583	DNA-binding transcription factor activity
AM354_RS23990	COG0411	ABC transporter
AM354_RS24020	COG2271	Major facilitator Superfamily
AM354_RS24040	COG2070	2-Nitropropane dioxygenase
AM354_RS24075	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AM354_RS24100	COG2814	Major facilitator Superfamily
AM354_RS24115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM354_RS24120	COG1121	(ABC) transporter
AM354_RS24130	COG2197	response regulator
AM354_RS24135	COG0583	DNA-binding transcription factor activity
AM354_RS24145	COG2207	Transcriptional regulator
AM354_RS24150	COG0300	oxidoreductase activity
AM354_RS24160	COG3250	beta-galactosidase activity
AM354_RS24165	COG4565	transcriptional regulatory protein
AM354_RS24170	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AM354_RS24175	COG3052	prosthetic group binding
AM354_RS24180	COG2301	Belongs to the HpcH HpaI aldolase family
AM354_RS24185	COG3051	citrate lyase alpha subunit
AM354_RS24195	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AM354_RS24200	COG0471	metal ion transport
AM354_RS24225	COG1169	isochorismate synthase
AM354_RS24230	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS24250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM354_RS24265	COG0025	NhaP-type Na H and K H
AM354_RS24285	COG0583	DNA-binding transcription factor activity
AM354_RS24305	COG1247	-acetyltransferase
AM354_RS24310	COG3238	Protein conserved in bacteria
AM354_RS24325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM354_RS24340	COG0656	L-ascorbic acid biosynthetic process
AM354_RS24355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM354_RS24360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM354_RS24365	COG1116	anion transmembrane transporter activity
AM354_RS24370	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM354_RS24375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM354_RS24385	COG4977	sequence-specific DNA binding
AM354_RS24390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM354_RS24400	COG3228	Belongs to the MtfA family
AM354_RS24425	COG3485	protocatechuate 3,4-dioxygenase
AM354_RS24430	COG3485	protocatechuate 3,4-dioxygenase
AM354_RS24435	COG0583	DNA-binding transcription factor activity
AM354_RS24440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM354_RS24450	COG0183	Belongs to the thiolase family
AM354_RS24455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM354_RS24460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM354_RS24465	COG1414	Transcriptional regulator
AM354_RS24510	COG3539	Fimbrial protein
AM354_RS24515	COG3188	usher protein
AM354_RS24520	COG3121	Chaperone
AM354_RS24530	COG3539	Fimbrial protein
AM354_RS24565	COG4993	Dehydrogenase
AM354_RS24570	COG4772	TonB-dependent receptor
AM354_RS24580	COG0667	Aldo Keto reductase
AM354_RS24620	COG0625	glutathione transferase activity
AM354_RS24625	COG0583	DNA-binding transcription factor activity
AM354_RS24645	COG1113	amino acid transport
AM354_RS24650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM354_RS24655	COG3327	negative regulation of DNA-templated transcription, initiation
AM354_RS24660	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM354_RS24665	COG0183	Belongs to the thiolase family
AM354_RS24670	COG2050	protein possibly involved in aromatic compounds catabolism
AM354_RS24675	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM354_RS24680	COG1024	Enoyl-CoA hydratase
AM354_RS24685	COG1024	Enoyl-CoA hydratase
AM354_RS24690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM354_RS24695	COG2151	metal-sulfur cluster biosynthetic enzyme
AM354_RS24700	COG3396	Phenylacetate-CoA oxygenase
AM354_RS24705	COG3460	Phenylacetate-CoA oxygenase
AM354_RS24710	COG3396	Phenylacetate-CoA oxygenase
AM354_RS24715	COG2030	dehydratase
AM354_RS24715	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS24725	COG3706	GGDEF domain
AM354_RS24725	COG4251	negative regulation of phosphorylation
AM354_RS24725	COG5001	Diguanylate cyclase
AM354_RS24725	COG2203	Gaf domain
AM354_RS24735	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM354_RS24740	COG1560	Kdo2-lipid A biosynthetic process
AM354_RS24750	COG2261	transglycosylase associated protein
AM354_RS24755	COG3753	Protein conserved in bacteria
AM354_RS24760	COG0583	DNA-binding transcription factor activity
AM354_RS24770	COG1028	Short-chain dehydrogenase reductase Sdr
AM354_RS24770	COG0604	alcohol dehydrogenase
AM354_RS24770	COG3321	synthase
AM354_RS24805	COG0076	glutamate decarboxylase activity
AM354_RS24815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM354_RS24825	COG1285	pathogenesis
AM354_RS24850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AM354_RS24860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM354_RS24870	COG2837	iron assimilation
AM354_RS24875	COG3781	membrane
AM354_RS24910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM354_RS24915	COG1629	transport
AM354_RS24920	COG1595	DNA-templated transcription, initiation
AM354_RS24925	COG3712	iron ion homeostasis
AM354_RS24935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM354_RS24940	COG4977	sequence-specific DNA binding
AM354_RS24945	COG1335	isochorismatase
AM354_RS24975	COG2207	Transcriptional regulator
AM354_RS24980	COG3059	membrane
AM354_RS24990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM354_RS24995	COG3483	tryptophan 2,3-dioxygenase activity
AM354_RS25000	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM354_RS25185	COG2130	NADP-dependent
AM354_RS25190	COG0589	response to stress
AM354_RS25230	COG0643	Histidine kinase
AM354_RS25230	COG2198	Histidine kinase
AM354_RS25235	COG0835	chemotaxis
AM354_RS25240	COG0840	transmembrane signaling receptor activity
AM354_RS25245	COG0840	transmembrane signaling receptor activity
AM354_RS25250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AM354_RS25260	COG0745	RESPONSE REGULATOR receiver
AM354_RS25265	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AM354_RS25270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM354_RS25275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM354_RS25285	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AM354_RS25300	COG3418	PFAM FlgN family protein
AM354_RS25305	COG2747	anti-sigma28 factor FlgM
AM354_RS25315	COG1815	bacterial-type flagellum-dependent cell motility
AM354_RS25320	COG1558	bacterial-type flagellum-dependent cell motility
AM354_RS25325	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AM354_RS25365	COG1256	bacterial-type flagellum assembly
AM354_RS25425	COG2882	bacterial-type flagellum organization
AM354_RS25430	COG1157	protein secretion by the type III secretion system
AM354_RS25435	COG1317	bacterial-type flagellum organization
AM354_RS25440	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM354_RS25450	COG1677	Flagellar hook-basal body complex protein FliE
AM354_RS25465	COG0583	DNA-binding transcription factor activity
AM354_RS25500	COG1191	sigma factor activity
AM354_RS25510	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AM354_RS25515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM354_RS25520	COG0765	amino acid transport
AM354_RS25525	COG1126	abc transporter atp-binding protein
AM354_RS25530	COG0506	proline dehydrogenase activity
AM354_RS25530	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM354_RS25530	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM354_RS25540	COG0672	)-iron permease
AM354_RS25545	COG2822	iron ion transport
AM354_RS25555	COG1702	phosphate starvation-inducible protein PhoH
AM354_RS25565	COG0387	Pfam Sodium calcium exchanger
AM354_RS25570	COG2375	cellular response to nickel ion
AM354_RS25575	COG4572	Cation transport regulator
AM354_RS25580	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM354_RS25585	COG0583	DNA-binding transcription factor activity
AM354_RS25605	COG0601	transmembrane transport
AM354_RS25610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM354_RS25615	COG0444	Belongs to the ABC transporter superfamily
AM354_RS25620	COG4608	Belongs to the ABC transporter superfamily
AM354_RS25635	COG4932	domain protein
AM354_RS25640	COG2197	response regulator
AM354_RS25645	COG3850	Histidine kinase
AM354_RS25650	COG2223	nitrite transmembrane transporter activity
AM354_RS25655	COG3710	Transcriptional regulator
AM354_RS25660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM354_RS25665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM354_RS25695	COG1215	transferase activity, transferring glycosyl groups
AM354_RS25715	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM354_RS25720	COG1140	nitrate reductase beta subunit
AM354_RS25725	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM354_RS25730	COG2181	nitrate reductase activity
AM354_RS25735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM354_RS25740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM354_RS25790	COG1294	oxidase, subunit
AM354_RS25795	COG1271	oxidase subunit
AM354_RS25800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM354_RS25810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM354_RS25815	COG3138	arginine N-succinyltransferase
AM354_RS25820	COG1012	belongs to the aldehyde dehydrogenase family
AM354_RS25825	COG3724	N-succinylarginine dihydrolase activity
AM354_RS25830	COG2988	succinylglutamate desuccinylase activity
AM354_RS25855	COG1652	LysM domain
AM354_RS25870	COG2207	Transcriptional regulator
AM354_RS25915	COG1113	amino acid transport
AM354_RS25940	COG1496	oxidoreductase activity
AM354_RS25945	COG2226	methyltransferase
AM354_RS25950	COG1971	Probably functions as a manganese efflux pump
AM354_RS25955	COG4811	Protein of unknown function (DUF986)
AM354_RS25960	COG3716	PTS system mannose fructose sorbose family IID component
AM354_RS25965	COG3715	PTS system
AM354_RS25970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM354_RS25970	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM354_RS25975	COG1253	flavin adenine dinucleotide binding
AM354_RS25980	COG2200	EAL domain
AM354_RS25985	COG1760	l-serine dehydratase
AM354_RS25990	COG0494	nUDIX hydrolase
AM354_RS26000	COG1216	Glycosyl transferase, family 2
AM354_RS26005	COG3140	Belongs to the UPF0181 family
AM354_RS26010	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AM354_RS26020	COG0513	Belongs to the DEAD box helicase family
AM354_RS26025	COG3141	response to X-ray
AM354_RS26030	COG3097	Belongs to the UPF0267 family
AM354_RS26050	COG2999	glutathione oxidoreductase activity
AM354_RS26060	COG0477	Major facilitator Superfamily
AM354_RS26065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM354_RS26070	COG3132	Protein of unknown function, DUF480
AM354_RS26075	COG0673	inositol 2-dehydrogenase activity
AM354_RS26085	COG0018	arginyl-trna synthetase
AM354_RS26090	COG3102	Protein conserved in bacteria
AM354_RS26095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM354_RS26100	COG3142	Participates in the control of copper homeostasis
AM354_RS26165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM354_RS26170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM354_RS26180	COG1192	Involved in chromosome partitioning
AM354_RS26200	COG1525	nuclease
AM354_RS26225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD