locus-tag	class	description
AM371_RS00010	COG0457	Tetratricopeptide repeat
AM371_RS00015	COG1598	PFAM Uncharacterised protein family UPF0150
AM371_RS00025	COG3038	cytochrome b561
AM371_RS00030	COG0436	Aminotransferase
AM371_RS00045	COG3275	phosphorelay sensor kinase activity
AM371_RS00050	COG3279	Response regulator of the LytR AlgR family
AM371_RS00060	COG2223	nitrite transmembrane transporter activity
AM371_RS00075	COG1794	racemase activity, acting on amino acids and derivatives
AM371_RS00090	COG3961	Belongs to the TPP enzyme family
AM371_RS00095	COG0667	Aldo Keto reductase
AM371_RS00105	COG1914	H( )-stimulated, divalent metal cation uptake system
AM371_RS00110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM371_RS00125	COG3121	Chaperone
AM371_RS00130	COG3188	usher protein
AM371_RS00155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM371_RS00185	COG4592	Periplasmic binding protein
AM371_RS00190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM371_RS00195	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM371_RS00200	COG1120	ATPase activity
AM371_RS00205	COG2382	esterase
AM371_RS00210	COG4774	siderophore transport
AM371_RS00215	COG0747	negative chemotaxis
AM371_RS00235	COG4302	ethanolamine ammonia-lyase activity
AM371_RS00240	COG4303	Ethanolamine ammonia lyase large subunit
AM371_RS00255	COG0583	DNA-binding transcription factor activity
AM371_RS00260	COG0385	Bile acid
AM371_RS00265	COG3530	Putative quorum-sensing-regulated virulence factor
AM371_RS00270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM371_RS00275	COG3115	cell septum assembly
AM371_RS00280	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AM371_RS00290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS00295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM371_RS00305	COG2205	protein histidine kinase activity
AM371_RS00310	COG0745	RESPONSE REGULATOR receiver
AM371_RS00325	COG4208	sulfate ABC transporter
AM371_RS00330	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM371_RS00340	COG2837	iron assimilation
AM371_RS00355	COG3111	PFAM Bacterial OB fold (BOF) protein
AM371_RS00360	COG0456	acetyltransferase
AM371_RS00365	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM371_RS00370	COG0408	coproporphyrinogen oxidase activity
AM371_RS00375	COG1671	Belongs to the UPF0178 family
AM371_RS00385	COG1770	oligopeptidase
AM371_RS00400	COG0833	amino acid
AM371_RS00405	COG2040	homocysteine
AM371_RS00410	COG0280	phosphate acetyltransferase
AM371_RS00410	COG0281	malic enzyme
AM371_RS00435	COG0583	DNA-binding transcription factor activity
AM371_RS00440	COG3397	chitin binding
AM371_RS00445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM371_RS00450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM371_RS00455	COG0494	nUDIX hydrolase
AM371_RS00465	COG3850	Histidine kinase
AM371_RS00470	COG2197	response regulator
AM371_RS00480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM371_RS00500	COG1393	Belongs to the ArsC family
AM371_RS00505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM371_RS00510	COG1876	peptidase activity
AM371_RS00520	COG0400	carboxylic ester hydrolase activity
AM371_RS00525	COG1444	tRNA N-acetyltransferase activity
AM371_RS00530	COG2321	neutral zinc metallopeptidase
AM371_RS00535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM371_RS00540	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM371_RS00545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM371_RS00550	COG2716	regulation of RNA biosynthetic process
AM371_RS00555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM371_RS00560	COG0628	permease
AM371_RS00605	COG4783	chaperone-mediated protein folding
AM371_RS00610	COG1393	Belongs to the ArsC family
AM371_RS00615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM371_RS00625	COG2261	transglycosylase associated protein
AM371_RS00635	COG2233	PERMEase
AM371_RS00640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM371_RS00645	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM371_RS00650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM371_RS00655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM371_RS00685	COG3210	domain, Protein
AM371_RS00710	COG0573	inorganic phosphate transmembrane transporter activity
AM371_RS00715	COG0573	inorganic phosphate transmembrane transporter activity
AM371_RS00720	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM371_RS00735	COG2239	Acts as a magnesium transporter
AM371_RS00740	COG3447	MASE1 domain protein
AM371_RS00740	COG5002	protein histidine kinase activity
AM371_RS00740	COG5001	Diguanylate cyclase
AM371_RS00755	COG0443	Heat shock 70 kDa protein
AM371_RS00770	COG0667	Aldo Keto reductase
AM371_RS00775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM371_RS00780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM371_RS00785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM371_RS00790	COG2814	Major facilitator Superfamily
AM371_RS00795	COG2205	protein histidine kinase activity
AM371_RS00800	COG0745	RESPONSE REGULATOR receiver
AM371_RS00815	COG3422	double-strand break repair
AM371_RS00820	COG0826	peptidase U32
AM371_RS00825	COG1597	lipid kinase activity
AM371_RS00830	COG1830	Aldolase
AM371_RS00840	COG3730	PTS system glucitol sorbitol-specific
AM371_RS00855	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS00860	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS00865	COG1349	DNA-binding transcription factor activity
AM371_RS00880	COG0351	phosphomethylpyrimidine kinase
AM371_RS00885	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AM371_RS00900	COG2814	Major facilitator Superfamily
AM371_RS00920	COG1187	pseudouridine synthase activity
AM371_RS00940	COG0784	Response regulator, receiver
AM371_RS00940	COG2205	protein histidine kinase activity
AM371_RS00940	COG5002	protein histidine kinase activity
AM371_RS00950	COG1733	regulation of RNA biosynthetic process
AM371_RS01195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM371_RS01225	COG0582	viral genome integration into host DNA
AM371_RS01230	COG0519	Catalyzes the synthesis of GMP from XMP
AM371_RS01230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM371_RS01235	COG0517	IMP dehydrogenase activity
AM371_RS01235	COG0516	GMP reductase activity
AM371_RS01245	COG1570	exodeoxyribonuclease VII activity
AM371_RS01255	COG2271	Major facilitator Superfamily
AM371_RS01260	COG1609	Transcriptional regulator
AM371_RS01275	COG1645	bacterial-type flagellum-dependent swarming motility
AM371_RS01285	COG1160	GTP binding
AM371_RS01290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM371_RS01295	COG2976	Protein conserved in bacteria
AM371_RS01300	COG0124	histidyl-tRNA synthetase
AM371_RS01305	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM371_RS01310	COG1426	Protein conserved in bacteria
AM371_RS01320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM371_RS01325	COG0105	UTP biosynthetic process
AM371_RS01335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM371_RS01340	COG2975	iron-sulfur cluster assembly
AM371_RS01345	COG0633	Ferredoxin
AM371_RS01350	COG0443	Heat shock 70 kDa protein
AM371_RS01355	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM371_RS01360	COG0316	Belongs to the HesB IscA family
AM371_RS01365	COG0822	iron-sulfur transferase activity
AM371_RS01370	COG1104	cysteine desulfurase activity
AM371_RS01375	COG1959	2 iron, 2 sulfur cluster binding
AM371_RS01390	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM371_RS01395	COG3683	transport system, periplasmic component
AM371_RS01400	COG3711	transcriptional antiterminator
AM371_RS01405	COG2814	Major facilitator Superfamily
AM371_RS01410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM371_RS01415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM371_RS01415	COG1017	nitric oxide dioxygenase activity
AM371_RS01425	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AM371_RS01430	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS01435	COG1177	transmembrane transport
AM371_RS01440	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM371_RS01445	COG3842	ATPase activity
AM371_RS01450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM371_RS01460	COG0583	DNA-binding transcription factor activity
AM371_RS01475	COG0347	Belongs to the P(II) protein family
AM371_RS01480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM371_RS01480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM371_RS01485	COG2204	response regulator
AM371_RS01490	COG3170	Tfp pilus assembly protein FimV
AM371_RS01495	COG2205	protein histidine kinase activity
AM371_RS01505	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM371_RS01520	COG0560	Phosphoserine phosphatase
AM371_RS01525	COG1263	PTS System
AM371_RS01525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM371_RS01530	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM371_RS01535	COG1737	Transcriptional regulator
AM371_RS01540	COG2194	sulfuric ester hydrolase activity
AM371_RS01545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM371_RS01550	COG0736	holo-[acyl-carrier-protein] synthase activity
AM371_RS01555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM371_RS01560	COG1381	Involved in DNA repair and RecF pathway recombination
AM371_RS01565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM371_RS01570	COG0571	ribonuclease III activity
AM371_RS01580	COG0481	GTPase activity
AM371_RS01590	COG3086	response to oxidative stress
AM371_RS01595	COG3026	antisigma factor binding
AM371_RS01610	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM371_RS01615	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM371_RS01620	COG0513	Belongs to the DEAD box helicase family
AM371_RS01640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM371_RS01645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM371_RS01650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM371_RS01655	COG0497	DNA recombination
AM371_RS01660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM371_RS01665	COG2914	Belongs to the UPF0125 (RnfH) family
AM371_RS01670	COG2867	negative regulation of translational initiation
AM371_RS01675	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM371_RS01685	COG0582	viral genome integration into host DNA
AM371_RS01820	COG3182	Iron-regulated membrane protein
AM371_RS01830	COG0454	-acetyltransferase
AM371_RS01860	COG2388	GCN5-related N-acetyl-transferase
AM371_RS01865	COG3592	Divergent 4Fe-4S mono-cluster
AM371_RS01870	COG2259	Doxx family
AM371_RS01875	COG2840	Smr protein MutS2
AM371_RS01895	COG0477	Major facilitator Superfamily
AM371_RS01905	COG0477	Major facilitator Superfamily
AM371_RS01920	COG4575	ribosome binding
AM371_RS01930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM371_RS01935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM371_RS01940	COG1780	Probably involved in ribonucleotide reductase function
AM371_RS01970	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS01975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM371_RS01980	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM371_RS01985	COG3493	citrate carrier protein
AM371_RS02005	COG4176	ABC-type proline glycine betaine transport system permease component
AM371_RS02010	COG2113	Glycine betaine
AM371_RS02020	COG2814	Major facilitator Superfamily
AM371_RS02025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM371_RS02035	COG1846	Transcriptional regulator
AM371_RS02045	COG1566	PFAM secretion protein HlyD family protein
AM371_RS02050	COG2814	Major facilitator Superfamily
AM371_RS02055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM371_RS02060	COG3118	belongs to the thioredoxin family
AM371_RS02065	COG3148	PFAM DTW domain containing protein
AM371_RS02070	COG0045	succinate-CoA ligase (ADP-forming) activity
AM371_RS02070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM371_RS02070	COG1042	CoA-binding domain protein
AM371_RS02075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM371_RS02080	COG0477	Major facilitator Superfamily
AM371_RS02115	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM371_RS02125	COG2011	ABC-type metal ion transport system permease component
AM371_RS02140	COG1720	tRNA m6t6A37 methyltransferase activity
AM371_RS02145	COG0442	prolyl-tRNA aminoacylation
AM371_RS02150	COG3015	lipoprotein NlpE involved in copper resistance
AM371_RS02155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM371_RS02170	COG4568	rho-dependent transcription termination
AM371_RS02180	COG0037	tRNA processing
AM371_RS02185	COG3104	oligopeptide transport
AM371_RS02195	COG0531	amino acid
AM371_RS02200	COG3710	Transcriptional regulator
AM371_RS02205	COG0346	lactoylglutathione lyase activity
AM371_RS02215	COG1982	Orn Lys Arg decarboxylase major
AM371_RS02220	COG0825	malonyl-CoA metabolic process
AM371_RS02225	COG0587	DNA-directed DNA polymerase activity
AM371_RS02230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM371_RS02235	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM371_RS02240	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM371_RS02245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM371_RS02250	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM371_RS02255	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM371_RS02260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM371_RS02265	COG0750	zinc metalloprotease
AM371_RS02270	COG0575	Belongs to the CDS family
AM371_RS02280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM371_RS02285	COG0233	cytoplasmic translational termination
AM371_RS02290	COG0528	UMP kinase activity
AM371_RS02300	COG0052	Belongs to the universal ribosomal protein uS2 family
AM371_RS02310	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM371_RS02330	COG0564	pseudouridine synthase activity
AM371_RS02335	COG4953	penicillin-binding protein 1C
AM371_RS02340	COG2373	Large extracellular alpha-helical protein
AM371_RS02345	COG3098	single-species biofilm formation
AM371_RS02350	COG2814	Major facilitator Superfamily
AM371_RS02365	COG1611	Belongs to the LOG family
AM371_RS02370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM371_RS02375	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AM371_RS02380	COG2363	Small membrane protein
AM371_RS02385	COG0583	DNA-binding transcription factor activity
AM371_RS02395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM371_RS02400	COG2166	iron-sulfur cluster assembly
AM371_RS02405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM371_RS02410	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM371_RS02430	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM371_RS02435	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM371_RS02435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM371_RS02440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM371_RS02445	COG1074	ATP-dependent DNA helicase activity
AM371_RS02450	COG1025	Belongs to the peptidase M16 family
AM371_RS02455	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM371_RS02475	COG2165	general secretion pathway protein
AM371_RS02480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM371_RS02485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM371_RS02495	COG0494	nUDIX hydrolase
AM371_RS02500	COG3066	DNA modification
AM371_RS02505	COG0861	Integral membrane protein TerC family
AM371_RS02515	COG0667	Aldo Keto reductase
AM371_RS02520	COG0477	Major facilitator Superfamily
AM371_RS02525	COG0318	PFAM AMP-dependent synthetase and ligase
AM371_RS02525	COG0204	Acyl-transferase
AM371_RS02540	COG1609	Transcriptional regulator
AM371_RS02560	COG0583	DNA-binding transcription factor activity
AM371_RS02565	COG0583	DNA-binding transcription factor activity
AM371_RS02585	COG4178	(ABC) transporter
AM371_RS02595	COG3716	PTS system mannose fructose sorbose family IID component
AM371_RS02600	COG3715	PTS system
AM371_RS02605	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM371_RS02615	COG1349	DNA-binding transcription factor activity
AM371_RS02620	COG2807	transmembrane transport
AM371_RS02630	COG4615	Cyclic peptide transporter
AM371_RS02635	COG0582	viral genome integration into host DNA
AM371_RS02640	COG2197	response regulator
AM371_RS02645	COG2197	response regulator
AM371_RS02650	COG3539	Fimbrial protein
AM371_RS02665	COG3121	Chaperone
AM371_RS02675	COG0582	viral genome integration into host DNA
AM371_RS02685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM371_RS02700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM371_RS02725	COG0583	DNA-binding transcription factor activity
AM371_RS02730	COG1620	l-lactate permease
AM371_RS02735	COG1304	FMN binding
AM371_RS02745	COG2814	Major facilitator Superfamily
AM371_RS02755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM371_RS02760	COG1309	transcriptional regulator
AM371_RS02765	COG5265	(ABC) transporter
AM371_RS02770	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM371_RS02775	COG4942	peptidase
AM371_RS02780	COG3247	response to pH
AM371_RS02800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM371_RS02810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM371_RS02820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM371_RS02830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM371_RS02835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM371_RS02840	COG4974	Belongs to the 'phage' integrase family
AM371_RS02845	COG0716	FMN binding
AM371_RS02850	COG4452	Inner membrane protein CreD
AM371_RS02855	COG2205	protein histidine kinase activity
AM371_RS02860	COG0745	RESPONSE REGULATOR receiver
AM371_RS02870	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM371_RS02875	COG0354	folic acid binding
AM371_RS02885	COG1272	protein, Hemolysin III
AM371_RS02905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM371_RS02910	COG1940	carbohydrate kinase activity
AM371_RS02915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM371_RS02920	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS02925	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS02930	COG1129	ABC transporter
AM371_RS02940	COG1349	DNA-binding transcription factor activity
AM371_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS03010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM371_RS03010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM371_RS03015	COG0509	glycine decarboxylation via glycine cleavage system
AM371_RS03020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM371_RS03025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM371_RS03030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM371_RS03035	COG0006	proline dipeptidase activity
AM371_RS03040	COG3079	Belongs to the UPF0149 family
AM371_RS03045	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AM371_RS03055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM371_RS03060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM371_RS03070	COG0583	DNA-binding transcription factor activity
AM371_RS03080	COG1279	arginine transmembrane transporter activity
AM371_RS03085	COG1414	Transcriptional regulator
AM371_RS03090	COG1129	ABC transporter
AM371_RS03095	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS03115	COG2731	YhcH YjgK YiaL family protein
AM371_RS03125	COG1070	Carbohydrate kinase
AM371_RS03130	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AM371_RS03135	COG3623	hexulose-6-phosphate isomerase
AM371_RS03140	COG0235	Class ii aldolase
AM371_RS03145	COG0564	pseudouridine synthase activity
AM371_RS03150	COG3122	Protein conserved in bacteria
AM371_RS03165	COG2271	Major facilitator Superfamily
AM371_RS03180	COG0191	fructose-bisphosphate aldolase activity
AM371_RS03185	COG0126	phosphoglycerate kinase activity
AM371_RS03190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM371_RS03195	COG3842	ATPase activity
AM371_RS03200	COG1175	transmembrane transport
AM371_RS03215	COG1114	Component of the transport system for branched-chain amino acids
AM371_RS03220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM371_RS03225	COG0501	Belongs to the peptidase M48B family
AM371_RS03240	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AM371_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS03250	COG2267	carboxylic ester hydrolase activity
AM371_RS03275	COG1414	Transcriptional regulator
AM371_RS03280	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS03295	COG2146	nitrite reductase [NAD(P)H] activity
AM371_RS03300	COG2271	Major facilitator Superfamily
AM371_RS03310	COG0010	Belongs to the arginase family
AM371_RS03315	COG1166	arginine decarboxylase activity
AM371_RS03325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM371_RS03340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM371_RS03345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM371_RS03350	COG1120	ATPase activity
AM371_RS03355	COG4774	siderophore transport
AM371_RS03360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM371_RS03365	COG1643	Atp-dependent helicase
AM371_RS03370	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM371_RS03375	COG1489	DNA binding
AM371_RS03390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM371_RS03395	COG0617	tRNA 3'-terminal CCA addition
AM371_RS03400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM371_RS03410	COG2149	membrane
AM371_RS03415	COG0642	Histidine kinase
AM371_RS03425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM371_RS03430	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM371_RS03435	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM371_RS03440	COG0726	polysaccharide deacetylase
AM371_RS03445	COG0842	Transport permease protein
AM371_RS03450	COG1131	(ABC) transporter
AM371_RS03455	COG0288	reversible hydration of carbon dioxide
AM371_RS03465	COG2132	Multicopper oxidase
AM371_RS03475	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AM371_RS03480	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AM371_RS03485	COG3112	Uncharacterised protein family (UPF0231)
AM371_RS03495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM371_RS03500	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM371_RS03505	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM371_RS03510	COG2186	Transcriptional regulator
AM371_RS03515	COG1113	amino acid transport
AM371_RS03520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM371_RS03520	COG2010	Cytochrome c
AM371_RS03530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM371_RS03530	COG2010	Cytochrome c
AM371_RS03540	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM371_RS03545	COG3708	Transcriptional regulator
AM371_RS03545	COG2207	Transcriptional regulator
AM371_RS03555	COG3091	SprT-like family
AM371_RS03560	COG2356	endonuclease I
AM371_RS03565	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM371_RS03570	COG0189	ligase activity
AM371_RS03575	COG1678	Uncharacterized ACR, COG1678
AM371_RS03580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM371_RS03585	COG2805	Type II/IV secretion system protein
AM371_RS03590	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM371_RS03595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM371_RS03600	COG0762	integral membrane protein
AM371_RS03605	COG1872	DUF167
AM371_RS03615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM371_RS03630	COG2066	Belongs to the glutaminase family
AM371_RS03635	COG3171	Protein conserved in bacteria
AM371_RS03640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM371_RS03650	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AM371_RS03655	COG0741	lytic transglycosylase activity
AM371_RS03660	COG1982	Orn Lys Arg decarboxylase major
AM371_RS03685	COG3539	Fimbrial protein
AM371_RS03695	COG3121	Chaperone
AM371_RS03705	COG3188	usher protein
AM371_RS03745	COG2819	hydrolase of the alpha beta superfamily
AM371_RS03750	COG0454	-acetyltransferase
AM371_RS03790	COG4772	TonB-dependent receptor
AM371_RS03795	COG0583	DNA-binding transcription factor activity
AM371_RS03800	COG1473	amidohydrolase
AM371_RS03805	COG1473	amidohydrolase
AM371_RS03810	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM371_RS03840	COG0848	biopolymer transport protein
AM371_RS03855	COG0586	Pfam SNARE associated Golgi protein
AM371_RS03860	COG2207	Transcriptional regulator
AM371_RS03865	COG1979	alcohol dehydrogenase
AM371_RS03870	COG0656	L-ascorbic acid biosynthetic process
AM371_RS03875	COG0741	lytic transglycosylase activity
AM371_RS03895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM371_RS03900	COG2211	Major facilitator Superfamily
AM371_RS03905	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM371_RS03910	COG0583	DNA-binding transcription factor activity
AM371_RS03915	COG2132	Multicopper oxidase
AM371_RS03920	COG0204	Acyl-transferase
AM371_RS03925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM371_RS03930	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM371_RS03935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM371_RS03940	COG0583	DNA-binding transcription factor activity
AM371_RS03945	COG0187	DNA topoisomerase II activity
AM371_RS03950	COG3150	esterase
AM371_RS03955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM371_RS03960	COG3151	Protein conserved in bacteria
AM371_RS03965	COG0494	nUDIX hydrolase
AM371_RS03970	COG1538	Outer membrane efflux protein
AM371_RS03980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM371_RS03980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS03980	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AM371_RS03985	COG1461	Dihydroxyacetone kinase
AM371_RS03990	COG2376	Dihydroxyacetone kinase
AM371_RS04000	COG5463	Belongs to the UPF0441 family
AM371_RS04005	COG0754	glutathionylspermidine amidase activity
AM371_RS04010	COG3384	dioxygenase
AM371_RS04020	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM371_RS04030	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AM371_RS04030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AM371_RS04035	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM371_RS04040	COG3025	triphosphatase activity
AM371_RS04045	COG4991	sh3 domain protein
AM371_RS04050	COG0617	tRNA 3'-terminal CCA addition
AM371_RS04055	COG1968	undecaprenyl-diphosphatase activity
AM371_RS04060	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM371_RS04065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AM371_RS04070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM371_RS04075	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM371_RS04080	COG0358	DNA primase activity
AM371_RS04145	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM371_RS04225	COG4695	Portal protein
AM371_RS04240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM371_RS04275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM371_RS04310	COG4974	Belongs to the 'phage' integrase family
AM371_RS04325	COG0625	glutathione transferase activity
AM371_RS04335	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS04340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM371_RS04350	COG0488	(ABC) transporter
AM371_RS04355	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM371_RS04355	COG1902	pentaerythritol trinitrate reductase activity
AM371_RS04360	COG2813	Specifically methylates the guanine in position
AM371_RS04365	COG1451	nucleotide metabolic process
AM371_RS04370	COG0673	inositol 2-dehydrogenase activity
AM371_RS04380	COG0861	Integral membrane protein TerC family
AM371_RS04385	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AM371_RS04390	COG2721	sulfolactate sulfo-lyase activity
AM371_RS04395	COG1904	glucuronate isomerase
AM371_RS04400	COG2271	Major facilitator Superfamily
AM371_RS04415	COG0586	Pfam SNARE associated Golgi protein
AM371_RS04420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM371_RS04430	COG4575	ribosome binding
AM371_RS04435	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM371_RS04445	COG2259	Doxx family
AM371_RS04450	COG0435	Glutathione S-transferase
AM371_RS04455	COG0583	DNA-binding transcription factor activity
AM371_RS04460	COG1741	Belongs to the pirin family
AM371_RS04470	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM371_RS04475	COG3107	peptidoglycan biosynthetic process
AM371_RS04480	COG0792	nuclease activity
AM371_RS04485	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM371_RS04490	COG2823	Periplasmic or secreted lipoprotein
AM371_RS04500	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM371_RS04505	COG0784	Response regulator, receiver
AM371_RS04505	COG2198	Histidine kinase
AM371_RS04505	COG5002	protein histidine kinase activity
AM371_RS04515	COG1242	4 iron, 4 sulfur cluster binding
AM371_RS04525	COG0069	glutamate synthase activity
AM371_RS04525	COG0067	glutamate synthase
AM371_RS04525	COG0070	glutamate synthase
AM371_RS04530	COG0493	'glutamate synthase
AM371_RS04540	COG2969	positive regulation of protein catabolic process
AM371_RS04545	COG0625	glutathione transferase activity
AM371_RS04555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM371_RS04560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM371_RS04565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM371_RS04570	COG3105	Protein conserved in bacteria
AM371_RS04575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM371_RS04580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM371_RS04585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM371_RS04590	COG5007	Belongs to the BolA IbaG family
AM371_RS04595	COG3113	response to antibiotic
AM371_RS04600	COG2854	intermembrane phospholipid transfer
AM371_RS04605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM371_RS04610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM371_RS04615	COG1127	ABC transporter
AM371_RS04620	COG0530	calcium, potassium:sodium antiporter activity
AM371_RS04625	COG0517	IMP dehydrogenase activity
AM371_RS04625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM371_RS04630	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM371_RS04635	COG3117	lipopolysaccharide transmembrane transporter activity
AM371_RS04640	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM371_RS04645	COG1137	ATPase activity
AM371_RS04650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM371_RS04665	COG1660	Displays ATPase and GTPase activities
AM371_RS04670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS04675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS04675	COG3711	transcriptional antiterminator
AM371_RS04695	COG3964	amidohydrolase
AM371_RS04725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM371_RS04735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM371_RS04745	COG2207	Transcriptional regulator
AM371_RS04750	COG3783	Cytochrome b(562)
AM371_RS04755	COG0312	modulator of DNA gyrase
AM371_RS04770	COG3028	Belongs to the UPF0307 family
AM371_RS04775	COG2732	(Barnase) inhibitor
AM371_RS04785	COG1289	transmembrane transporter activity
AM371_RS04790	COG1566	PFAM secretion protein HlyD family protein
AM371_RS04800	COG0583	DNA-binding transcription factor activity
AM371_RS04825	COG2134	cdp-diacylglycerol pyrophosphatase
AM371_RS04830	COG0312	modulator of DNA gyrase
AM371_RS04835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM371_RS04840	COG3164	Protein of unknown function
AM371_RS04845	COG1530	ribonuclease E activity
AM371_RS04850	COG0424	maF-like protein
AM371_RS04855	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM371_RS04860	COG1792	Involved in formation and maintenance of cell shape
AM371_RS04865	COG1077	Cell shape determining protein MreB Mrl
AM371_RS04870	COG2200	EAL domain
AM371_RS04870	COG2199	diguanylate cyclase activity
AM371_RS04875	COG0604	alcohol dehydrogenase
AM371_RS04880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM371_RS04885	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AM371_RS04890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM371_RS04895	COG0511	ligase activity, forming carbon-carbon bonds
AM371_RS04900	COG0439	Biotin carboxylase
AM371_RS04905	COG3924	membrane
AM371_RS04910	COG4145	pantothenate transmembrane transporter activity
AM371_RS04915	COG2264	protein methyltransferase activity
AM371_RS04940	COG1560	Kdo2-lipid A biosynthetic process
AM371_RS04945	COG0504	CTP synthase activity
AM371_RS04960	COG1380	Effector of murein hydrolase LrgA
AM371_RS04965	COG0583	DNA-binding transcription factor activity
AM371_RS04970	COG0025	NhaP-type Na H and K H
AM371_RS04975	COG2252	PERMEase
AM371_RS04985	COG0625	glutathione transferase activity
AM371_RS05000	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS05015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM371_RS05020	COG1064	alcohol dehydrogenase
AM371_RS05025	COG0110	maltose O-acetyltransferase activity
AM371_RS05030	COG2315	Protein conserved in bacteria
AM371_RS05040	COG1448	Aminotransferase
AM371_RS05045	COG1522	sequence-specific DNA binding
AM371_RS05065	COG0604	alcohol dehydrogenase
AM371_RS05075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM371_RS05085	COG0735	belongs to the Fur family
AM371_RS05090	COG3237	CsbD-like
AM371_RS05095	COG0534	Mate efflux family protein
AM371_RS05100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM371_RS05105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM371_RS05110	COG2937	Belongs to the GPAT DAPAT family
AM371_RS05115	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM371_RS05120	COG3161	chorismate lyase activity
AM371_RS05125	COG0477	Major facilitator Superfamily
AM371_RS05130	COG1609	Transcriptional regulator
AM371_RS05145	COG4580	involved in the transport of maltose and maltodextrins
AM371_RS05155	COG0366	Alpha amylase catalytic
AM371_RS05160	COG2182	Extracellular solute-binding protein
AM371_RS05165	COG1175	transmembrane transport
AM371_RS05170	COG3833	ABC-type maltose transport systems, permease component
AM371_RS05175	COG3223	Belongs to the PsiE family
AM371_RS05185	COG0166	Belongs to the GPI family
AM371_RS05195	COG0527	aspartate kinase activity
AM371_RS05215	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM371_RS05220	COG3842	ATPase activity
AM371_RS05230	COG0395	ABC-type sugar transport system, permease component
AM371_RS05245	COG2188	Transcriptional regulator
AM371_RS05250	COG0646	methionine synthase
AM371_RS05250	COG1410	methionine synthase
AM371_RS05255	COG1414	Transcriptional regulator
AM371_RS05260	COG3265	gluconokinase activity
AM371_RS05265	COG2610	gluconate transmembrane transporter activity
AM371_RS05270	COG0129	dihydroxy-acid dehydratase activity
AM371_RS05275	COG0800	Aldolase
AM371_RS05280	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AM371_RS05290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM371_RS05295	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AM371_RS05330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM371_RS05335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM371_RS05340	COG0009	L-threonylcarbamoyladenylate synthase
AM371_RS05345	COG0551	DNA topoisomerase type I activity
AM371_RS05350	COG2922	Belongs to the Smg family
AM371_RS05355	COG0758	DNA mediated transformation
AM371_RS05360	COG0242	peptide deformylase activity
AM371_RS05365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM371_RS05370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM371_RS05370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM371_RS05375	COG0569	domain protein
AM371_RS05380	COG1970	mechanosensitive ion channel activity
AM371_RS05385	COG3036	rescue of stalled ribosome
AM371_RS05390	COG0789	Transcriptional regulator
AM371_RS05400	COG0203	ribosomal protein L17
AM371_RS05405	COG0202	RNA polymerase activity
AM371_RS05410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM371_RS05415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM371_RS05420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM371_RS05425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM371_RS05430	COG0201	protein transport
AM371_RS05440	COG1841	ribosomal large subunit assembly
AM371_RS05445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM371_RS05450	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM371_RS05455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM371_RS05495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM371_RS05500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AM371_RS05510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM371_RS05520	COG0089	rRNA binding
AM371_RS05525	COG0088	Forms part of the polypeptide exit tunnel
AM371_RS05530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM371_RS05535	COG0051	transcription antitermination factor activity, RNA binding
AM371_RS05550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM371_RS05560	COG0049	tRNA binding
AM371_RS05565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM371_RS05570	COG2168	tRNA wobble position uridine thiolation
AM371_RS05575	COG2923	Belongs to the DsrF TusC family
AM371_RS05580	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM371_RS05585	COG2964	Protein conserved in bacteria
AM371_RS05590	COG0545	Peptidyl-prolyl cis-trans isomerase
AM371_RS05595	COG2900	Belongs to the SlyX family
AM371_RS05600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM371_RS05605	COG1757	Na H antiporter
AM371_RS05610	COG1609	Transcriptional regulator
AM371_RS05615	COG1047	Peptidyl-prolyl cis-trans
AM371_RS05620	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM371_RS05630	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM371_RS05635	COG0488	(ABC) transporter
AM371_RS05640	COG2175	clavaminate synthase activity
AM371_RS05645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM371_RS05655	COG4521	taurine ABC transporter
AM371_RS05670	COG0429	hydrolase of the alpha beta-hydrolase fold
AM371_RS05675	COG3089	Belongs to the UPF0270 family
AM371_RS05680	COG3954	Phosphoribulokinase
AM371_RS05685	COG1765	OsmC-like protein
AM371_RS05690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM371_RS05695	COG1289	transmembrane transporter activity
AM371_RS05710	COG0433	COG0433 Predicted ATPase
AM371_RS05730	COG3275	phosphorelay sensor kinase activity
AM371_RS05735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM371_RS05745	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM371_RS05750	COG1486	melibiose metabolic process
AM371_RS05755	COG1609	Transcriptional regulator
AM371_RS05760	COG0738	Major facilitator superfamily
AM371_RS05765	COG0402	S-adenosylhomocysteine deaminase activity
AM371_RS05775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM371_RS05790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM371_RS05790	COG1648	precorrin-2 dehydrogenase activity
AM371_RS05795	COG0180	Tryptophanyl-tRNA synthetase
AM371_RS05800	COG0546	phosphoglycolate phosphatase activity
AM371_RS05820	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM371_RS05825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM371_RS05830	COG4796	Type ii and iii secretion system protein
AM371_RS05855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM371_RS05860	COG0494	nUDIX hydrolase
AM371_RS05870	COG1011	Hydrolase
AM371_RS05875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM371_RS05880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM371_RS05915	COG0484	heat shock protein binding
AM371_RS05920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM371_RS05925	COG2183	response to ionizing radiation
AM371_RS05930	COG1918	ferrous iron import across plasma membrane
AM371_RS05955	COG1040	competence protein
AM371_RS05960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM371_RS05960	COG0316	Belongs to the HesB IscA family
AM371_RS05965	COG1640	4-alpha-glucanotransferase
AM371_RS05970	COG0058	SHG alpha-glucan phosphorylase activity
AM371_RS05975	COG2909	trisaccharide binding
AM371_RS06020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM371_RS06025	COG0705	Rhomboid family
AM371_RS06030	COG1349	DNA-binding transcription factor activity
AM371_RS06035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM371_RS06040	COG0058	SHG alpha-glucan phosphorylase activity
AM371_RS06045	COG0297	glycogen (starch) synthase activity
AM371_RS06050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM371_RS06055	COG1523	belongs to the glycosyl hydrolase 13 family
AM371_RS06060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AM371_RS06065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM371_RS06070	COG2095	MarC family integral membrane protein
AM371_RS06075	COG3265	gluconokinase activity
AM371_RS06080	COG2610	gluconate transmembrane transporter activity
AM371_RS06085	COG1609	Transcriptional regulator
AM371_RS06090	COG1741	Belongs to the pirin family
AM371_RS06095	COG1247	-acetyltransferase
AM371_RS06100	COG3191	aminopeptidase activity
AM371_RS06105	COG1082	Xylose isomerase domain protein TIM barrel
AM371_RS06110	COG1082	Xylose isomerase domain protein TIM barrel
AM371_RS06115	COG0673	inositol 2-dehydrogenase activity
AM371_RS06120	COG3962	Belongs to the TPP enzyme family
AM371_RS06125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM371_RS06145	COG3718	enzyme involved in inositol metabolism
AM371_RS06155	COG2814	Major facilitator Superfamily
AM371_RS06155	COG0477	Major facilitator Superfamily
AM371_RS06165	COG0390	transport system, permease component
AM371_RS06170	COG4619	ABC transporter
AM371_RS06190	COG3188	usher protein
AM371_RS06215	COG2197	response regulator
AM371_RS06225	COG2130	NADP-dependent
AM371_RS06250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM371_RS06265	COG0697	spore germination
AM371_RS06285	COG0346	lactoylglutathione lyase activity
AM371_RS06290	COG2081	HI0933 family
AM371_RS06295	COG0306	phosphate transporter
AM371_RS06315	COG0475	glutathione-regulated potassium exporter activity
AM371_RS06315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM371_RS06325	COG0583	DNA-binding transcription factor activity
AM371_RS06330	COG0589	response to stress
AM371_RS06345	COG1129	ABC transporter
AM371_RS06350	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS06355	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS06370	COG0742	ribosomal rna small subunit methyltransferase
AM371_RS06375	COG0339	signal peptide processing
AM371_RS06400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM371_RS06405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM371_RS06415	COG2205	protein histidine kinase activity
AM371_RS06415	COG0784	Response regulator, receiver
AM371_RS06440	COG5441	Belongs to the UPF0261 family
AM371_RS06445	COG3678	ATP-independent chaperone mediated protein folding
AM371_RS06450	COG5001	Diguanylate cyclase
AM371_RS06455	COG1024	Enoyl-CoA hydratase
AM371_RS06460	COG1295	ribonuclease BN
AM371_RS06465	COG0477	Major facilitator Superfamily
AM371_RS06470	COG2134	cdp-diacylglycerol pyrophosphatase
AM371_RS06475	COG2982	Protein involved in outer membrane biogenesis
AM371_RS06480	COG2200	EAL domain
AM371_RS06485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM371_RS06495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM371_RS06515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM371_RS06520	COG0129	dihydroxy-acid dehydratase activity
AM371_RS06525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM371_RS06530	COG3978	acetolactate synthase activity
AM371_RS06545	COG2814	Major facilitator Superfamily
AM371_RS06555	COG3085	chromosome segregation
AM371_RS06560	COG0583	DNA-binding transcription factor activity
AM371_RS06600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM371_RS06605	COG4206	TonB-dependent receptor
AM371_RS06610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM371_RS06625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM371_RS06635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM371_RS06635	COG0678	peroxiredoxin activity
AM371_RS06640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM371_RS06650	COG0165	Argininosuccinate lyase
AM371_RS06655	COG0137	argininosuccinate synthase activity
AM371_RS06660	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM371_RS06675	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AM371_RS06685	COG0460	homoserine dehydrogenase
AM371_RS06685	COG0527	aspartate kinase activity
AM371_RS06690	COG0626	cystathionine gamma-synthase activity
AM371_RS06695	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AM371_RS06700	COG0254	rRNA binding
AM371_RS06705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM371_RS06710	COG1609	Transcriptional regulator
AM371_RS06715	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM371_RS06720	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AM371_RS06725	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AM371_RS06730	COG1575	Belongs to the MenA family. Type 1 subfamily
AM371_RS06735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM371_RS06740	COG3074	FtsZ-dependent cytokinesis
AM371_RS06755	COG1494	fructose-1,6-bisphosphatase
AM371_RS06760	COG2814	Major facilitator Superfamily
AM371_RS06775	COG3152	Membrane
AM371_RS06785	COG0149	triose-phosphate isomerase activity
AM371_RS06790	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM371_RS06795	COG0205	6-phosphofructokinase activity
AM371_RS06800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM371_RS06805	COG3678	ATP-independent chaperone mediated protein folding
AM371_RS06810	COG0745	RESPONSE REGULATOR receiver
AM371_RS06815	COG2205	protein histidine kinase activity
AM371_RS06820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM371_RS06835	COG1045	serine acetyltransferase
AM371_RS06850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM371_RS06855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM371_RS06860	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM371_RS06865	COG4942	peptidase
AM371_RS06870	COG2861	carbohydrate metabolic process
AM371_RS06875	COG1063	alcohol dehydrogenase
AM371_RS06880	COG0156	8-amino-7-oxononanoate synthase activity
AM371_RS06885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM371_RS06890	COG0859	PFAM glycosyl transferase family 9
AM371_RS06895	COG0859	PFAM glycosyl transferase family 9
AM371_RS06900	COG0438	transferase activity, transferring glycosyl groups
AM371_RS06905	COG3307	-O-antigen
AM371_RS06910	COG1442	glycosyl transferase family 8
AM371_RS06910	COG1216	Glycosyl transferase, family 2
AM371_RS06925	COG0859	PFAM glycosyl transferase family 9
AM371_RS06930	COG0438	transferase activity, transferring glycosyl groups
AM371_RS06935	COG0438	transferase activity, transferring glycosyl groups
AM371_RS06945	COG1519	Transferase
AM371_RS06970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM371_RS06975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM371_RS06980	COG2003	Belongs to the UPF0758 family
AM371_RS06985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM371_RS06990	COG0756	dUTP diphosphatase activity
AM371_RS06995	COG1309	transcriptional regulator
AM371_RS07000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM371_RS07005	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM371_RS07010	COG1561	YicC-like family, N-terminal region
AM371_RS07020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM371_RS07030	COG2860	membrane
AM371_RS07035	COG0194	GDP metabolic process
AM371_RS07040	COG1758	RNA polymerase activity
AM371_RS07045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM371_RS07050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM371_RS07055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM371_RS07060	COG0786	glutamate:sodium symporter activity
AM371_RS07065	COG2233	PERMEase
AM371_RS07070	COG2982	Protein involved in outer membrane biogenesis
AM371_RS07075	COG0456	acetyltransferase
AM371_RS07080	COG1490	D-aminoacyl-tRNA deacylase activity
AM371_RS07085	COG1295	ribonuclease BN
AM371_RS07090	COG1011	Hydrolase
AM371_RS07095	COG1217	gtp-binding protein TYPA
AM371_RS07110	COG3852	Histidine kinase
AM371_RS07120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM371_RS07130	COG3078	GTPase activator activity
AM371_RS07140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AM371_RS07145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM371_RS07145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM371_RS07150	COG0204	Acyl-transferase
AM371_RS07155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM371_RS07160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM371_RS07165	COG3084	Protein conserved in bacteria
AM371_RS07170	COG0746	molybdenum cofactor guanylyltransferase activity
AM371_RS07175	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM371_RS07200	COG2186	Transcriptional regulator
AM371_RS07205	COG0477	Major facilitator Superfamily
AM371_RS07210	COG1609	Transcriptional regulator
AM371_RS07215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM371_RS07225	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS07230	COG1129	ABC transporter
AM371_RS07235	COG1869	D-ribose catabolic process
AM371_RS07240	COG3158	transport of potassium into the cell
AM371_RS07245	COG0714	Associated with various cellular activities
AM371_RS07250	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM371_RS07255	COG2502	aspartate--ammonia ligase
AM371_RS07260	COG1522	sequence-specific DNA binding
AM371_RS07265	COG0716	FMN binding
AM371_RS07270	COG0445	tRNA wobble uridine modification
AM371_RS07275	COG0357	Ribosomal RNA small subunit methyltransferase G
AM371_RS07280	COG3312	ion transport
AM371_RS07295	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM371_RS07300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM371_RS07305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM371_RS07310	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM371_RS07315	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM371_RS07320	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM371_RS07325	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM371_RS07335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM371_RS07340	COG0573	inorganic phosphate transmembrane transporter activity
AM371_RS07345	COG0581	inorganic phosphate transmembrane transporter activity
AM371_RS07355	COG0704	Plays a role in the regulation of phosphate uptake
AM371_RS07360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM371_RS07365	COG0765	amino acid transport
AM371_RS07370	COG0765	amino acid transport
AM371_RS07375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM371_RS07380	COG0494	nUDIX hydrolase
AM371_RS07385	COG2252	PERMEase
AM371_RS07395	COG0431	NADPH-dependent FMN reductase
AM371_RS07400	COG2091	lysine biosynthetic process via aminoadipic acid
AM371_RS07410	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM371_RS07415	COG0706	membrane insertase activity
AM371_RS07420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM371_RS07425	COG0594	ribonuclease P activity
AM371_RS07435	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM371_RS07440	COG0592	DNA-directed DNA polymerase activity
AM371_RS07445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM371_RS07450	COG0187	DNA topoisomerase II activity
AM371_RS07455	COG0561	phosphatase activity
AM371_RS07460	COG2423	ornithine cyclodeaminase activity
AM371_RS07465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM371_RS07475	COG0823	Involved in the tonB-independent uptake of proteins
AM371_RS07480	COG5645	(Lipo)protein
AM371_RS07485	COG0071	Belongs to the small heat shock protein (HSP20) family
AM371_RS07490	COG0071	Belongs to the small heat shock protein (HSP20) family
AM371_RS07495	COG2985	domain, Protein
AM371_RS07510	COG3977	Valine--pyruvate aminotransferase
AM371_RS07515	COG0366	Alpha amylase catalytic
AM371_RS07520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM371_RS07525	COG2814	Major facilitator Superfamily
AM371_RS07530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM371_RS07540	COG1609	Transcriptional regulator
AM371_RS07545	COG2885	chlorophyll binding
AM371_RS07555	COG2818	Glycosylase
AM371_RS07565	COG0752	glycyl-tRNA synthetase alpha subunit
AM371_RS07570	COG0751	glycine-tRNA ligase activity
AM371_RS07580	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS07580	COG2213	PTS system mannitol-specific
AM371_RS07585	COG0246	Mannitol dehydrogenase
AM371_RS07590	COG3722	fumarate hydratase activity
AM371_RS07600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM371_RS07615	COG2258	MOSC domain
AM371_RS07620	COG0840	transmembrane signaling receptor activity
AM371_RS07625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM371_RS07630	COG3383	formate dehydrogenase (NAD+) activity
AM371_RS07630	COG0243	molybdopterin cofactor binding
AM371_RS07635	COG3383	formate dehydrogenase (NAD+) activity
AM371_RS07635	COG0243	molybdopterin cofactor binding
AM371_RS07640	COG0437	4 iron, 4 sulfur cluster binding
AM371_RS07645	COG2864	formate dehydrogenase
AM371_RS07650	COG3058	Necessary for formate dehydrogenase activity
AM371_RS07660	COG0625	glutathione transferase activity
AM371_RS07665	COG1921	L-seryl-tRNASec selenium transferase activity
AM371_RS07670	COG3276	selenocysteine insertion sequence binding
AM371_RS07685	COG0583	DNA-binding transcription factor activity
AM371_RS07700	COG3274	enterobacterial common antigen metabolic process
AM371_RS07710	COG1335	isochorismatase
AM371_RS07715	COG0402	S-adenosylhomocysteine deaminase activity
AM371_RS07730	COG0583	DNA-binding transcription factor activity
AM371_RS07735	COG2807	transmembrane transport
AM371_RS07745	COG0582	viral genome integration into host DNA
AM371_RS07845	COG2814	Major facilitator Superfamily
AM371_RS07875	COG1846	Transcriptional regulator
AM371_RS07880	COG1764	response to oxidative stress
AM371_RS07885	COG2194	sulfuric ester hydrolase activity
AM371_RS07890	COG2197	response regulator
AM371_RS07900	COG2271	Major facilitator Superfamily
AM371_RS07920	COG0747	negative chemotaxis
AM371_RS07925	COG0601	transmembrane transport
AM371_RS07930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM371_RS07935	COG0444	Belongs to the ABC transporter superfamily
AM371_RS07940	COG4608	Belongs to the ABC transporter superfamily
AM371_RS07945	COG2194	sulfuric ester hydrolase activity
AM371_RS07975	COG1215	transferase activity, transferring glycosyl groups
AM371_RS07980	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM371_RS07985	COG0457	Tetratricopeptide repeat
AM371_RS07985	COG3118	belongs to the thioredoxin family
AM371_RS07990	COG2200	EAL domain
AM371_RS07990	COG2199	diguanylate cyclase activity
AM371_RS07995	COG1301	dicarboxylic acid transport
AM371_RS08000	COG0612	Peptidase, M16
AM371_RS08005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM371_RS08015	COG0248	Ppx GppA phosphatase
AM371_RS08025	COG3118	belongs to the thioredoxin family
AM371_RS08030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM371_RS08035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM371_RS08045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM371_RS08050	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM371_RS08055	COG1088	dTDP-glucose 4,6-dehydratase activity
AM371_RS08060	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM371_RS08065	COG0456	acetyltransferase
AM371_RS08070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM371_RS08075	COG2244	polysaccharide biosynthetic process
AM371_RS08080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM371_RS08090	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM371_RS08120	COG3071	HemY protein
AM371_RS08125	COG2959	enzyme of heme biosynthesis
AM371_RS08130	COG1587	Uroporphyrinogen-III synthase
AM371_RS08135	COG0181	hydroxymethylbilane synthase activity
AM371_RS08140	COG3072	Adenylate cyclase
AM371_RS08145	COG1965	Belongs to the frataxin family
AM371_RS08150	COG5567	small periplasmic lipoprotein
AM371_RS08155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM371_RS08160	COG3159	Protein conserved in bacteria
AM371_RS08170	COG1011	Hydrolase
AM371_RS08175	COG0210	DNA helicase
AM371_RS08200	COG2050	protein possibly involved in aromatic compounds catabolism
AM371_RS08210	COG0514	ATP-dependent DNA helicase (RecQ)
AM371_RS08215	COG1280	lysine exporter protein (LysE YggA)
AM371_RS08220	COG1280	lysine exporter protein (LysE YggA)
AM371_RS08225	COG2267	carboxylic ester hydrolase activity
AM371_RS08230	COG0561	phosphatase activity
AM371_RS08235	COG0584	glycerophosphoryl diester phosphodiesterase
AM371_RS08240	COG2271	Major facilitator Superfamily
AM371_RS08250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM371_RS08260	COG0247	lactate metabolic process
AM371_RS08275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM371_RS08280	COG0425	Belongs to the sulfur carrier protein TusA family
AM371_RS08285	COG2217	Heavy metal translocating P-type atpase
AM371_RS08300	COG3714	YhhN family
AM371_RS08310	COG3776	membrane
AM371_RS08315	COG0742	ribosomal rna small subunit methyltransferase
AM371_RS08320	COG0552	protein localization to endoplasmic reticulum
AM371_RS08320	COG0552	protein localization to endoplasmic reticulum
AM371_RS08325	COG2884	Cell division ATP-binding protein ftsE
AM371_RS08330	COG2177	Part of the ABC transporter FtsEX involved in
AM371_RS08350	COG0456	acetyltransferase
AM371_RS08360	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM371_RS08365	COG4177	L-phenylalanine transmembrane transporter activity
AM371_RS08375	COG0410	ABC transporter
AM371_RS08380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM371_RS08385	COG1653	transport
AM371_RS08390	COG1175	transmembrane transport
AM371_RS08400	COG3842	ATPase activity
AM371_RS08405	COG0584	glycerophosphoryl diester phosphodiesterase
AM371_RS08420	COG0697	spore germination
AM371_RS08430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM371_RS08435	COG0412	Dienelactone hydrolase
AM371_RS08450	COG0586	Pfam SNARE associated Golgi protein
AM371_RS08455	COG1322	Protein conserved in bacteria
AM371_RS08460	COG2226	methyltransferase
AM371_RS08465	COG3165	ubiquinone biosynthetic process from chorismate
AM371_RS08470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM371_RS08475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM371_RS08485	COG0805	protein transport
AM371_RS08490	COG0084	hydrolase, TatD family'
AM371_RS08520	COG0183	Belongs to the thiolase family
AM371_RS08525	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM371_RS08525	COG1024	Enoyl-CoA hydratase
AM371_RS08530	COG0006	proline dipeptidase activity
AM371_RS08535	COG1739	Uncharacterized protein family UPF0029
AM371_RS08540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM371_RS08570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM371_RS08575	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM371_RS08575	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM371_RS08580	COG1072	(Pantothenic acid kinase))
AM371_RS08615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM371_RS08625	COG0250	Participates in transcription elongation, termination and antitermination
AM371_RS08640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM371_RS08650	COG0085	RNA polymerase activity
AM371_RS08655	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM371_RS08670	COG5002	protein histidine kinase activity
AM371_RS08685	COG2022	thiamine diphosphate biosynthetic process
AM371_RS08690	COG2104	thiamine diphosphate biosynthetic process
AM371_RS08695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM371_RS08700	COG0352	thiamine-phosphate diphosphorylase activity
AM371_RS08705	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AM371_RS08710	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AM371_RS08715	COG2816	NAD+ diphosphatase activity
AM371_RS08720	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM371_RS08725	COG1515	deoxyribonuclease V activity
AM371_RS08745	COG0151	Belongs to the GarS family
AM371_RS08750	COG0138	bifunctional purine biosynthesis protein purh
AM371_RS08780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM371_RS08785	COG3162	membrane
AM371_RS08790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM371_RS08795	COG1301	dicarboxylic acid transport
AM371_RS08800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM371_RS08800	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM371_RS08805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM371_RS08805	COG2226	methyltransferase
AM371_RS08805	COG3433	isochorismatase activity
AM371_RS08810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM371_RS08815	COG1629	transport
AM371_RS08815	COG4774	siderophore transport
AM371_RS08820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM371_RS08825	COG3391	amine dehydrogenase activity
AM371_RS08830	COG4771	TonB-dependent receptor
AM371_RS08835	COG2382	esterase
AM371_RS08845	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM371_RS08845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM371_RS08855	COG1169	isochorismate synthase
AM371_RS08860	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM371_RS08865	COG3433	isochorismatase activity
AM371_RS08865	COG1535	isochorismatase
AM371_RS08875	COG3647	Membrane
AM371_RS08890	COG1309	transcriptional regulator
AM371_RS08895	COG4232	protein-disulfide reductase activity
AM371_RS08905	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM371_RS08920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM371_RS08930	COG0840	transmembrane signaling receptor activity
AM371_RS08940	COG1509	lysine 2,3-aminomutase activity
AM371_RS08945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM371_RS08950	COG5510	response to toxic substance
AM371_RS08955	COG5510	response to toxic substance
AM371_RS08970	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM371_RS08975	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM371_RS08980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM371_RS08985	COG1053	succinate dehydrogenase
AM371_RS08990	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM371_RS08995	COG3264	Mechanosensitive ion channel
AM371_RS08995	COG1511	domain protein
AM371_RS09000	COG0688	phosphatidylethanolamine metabolic process
AM371_RS09005	COG1162	GTPase activity
AM371_RS09010	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM371_RS09030	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM371_RS09035	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM371_RS09035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM371_RS09040	COG0802	atpase or kinase
AM371_RS09045	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM371_RS09050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM371_RS09055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM371_RS09065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM371_RS09070	COG0330	HflC and HflK could
AM371_RS09075	COG0330	HflC and HflK could
AM371_RS09080	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM371_RS09085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM371_RS09090	COG1959	2 iron, 2 sulfur cluster binding
AM371_RS09095	COG0557	exoribonuclease II activity
AM371_RS09100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM371_RS09105	COG1960	acyl-CoA dehydrogenase activity
AM371_RS09110	COG3766	membrane
AM371_RS09120	COG3650	response to hydrogen peroxide
AM371_RS09125	COG1073	alpha beta
AM371_RS09140	COG0360	Binds together with S18 to 16S ribosomal RNA
AM371_RS09150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM371_RS09155	COG0359	binds to the 23S rRNA
AM371_RS09165	COG3061	Opacity-associated protein A
AM371_RS09170	COG0545	Peptidyl-prolyl cis-trans isomerase
AM371_RS09180	COG0737	Belongs to the 5'-nucleotidase family
AM371_RS09190	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM371_RS09200	COG1253	flavin adenine dinucleotide binding
AM371_RS09205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM371_RS09210	COG0729	surface antigen
AM371_RS09215	COG2911	Protein conserved in bacteria
AM371_RS09220	COG2105	PFAM AIG2 family protein
AM371_RS09225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM371_RS09235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM371_RS09240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM371_RS09255	COG1438	arginine binding
AM371_RS09260	COG0039	L-malate dehydrogenase activity
AM371_RS09265	COG3423	Transcriptional regulator
AM371_RS09275	COG0142	geranyltranstransferase activity
AM371_RS09280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM371_RS09285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM371_RS09290	COG0697	spore germination
AM371_RS09295	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM371_RS09300	COG0642	Histidine kinase
AM371_RS09305	COG0745	RESPONSE REGULATOR receiver
AM371_RS09310	COG2027	D-alanyl-D-alanine carboxypeptidase
AM371_RS09320	COG1534	Rna-binding protein
AM371_RS09325	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AM371_RS09335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM371_RS09340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM371_RS09345	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM371_RS09360	COG0779	Required for maturation of 30S ribosomal subunits
AM371_RS09365	COG0195	Participates in both transcription termination and antitermination
AM371_RS09370	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM371_RS09375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM371_RS09380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM371_RS09385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM371_RS09395	COG1185	polyribonucleotide nucleotidyltransferase activity
AM371_RS09410	COG0513	Belongs to the DEAD box helicase family
AM371_RS09415	COG2391	methyltransferase activity
AM371_RS09420	COG0425	Belongs to the sulfur carrier protein TusA family
AM371_RS09425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM371_RS09450	COG0826	peptidase U32
AM371_RS09455	COG0826	peptidase U32
AM371_RS09460	COG3154	lipid carrier protein
AM371_RS09465	COG3153	acetyltransferase
AM371_RS09470	COG2827	Endonuclease containing a URI domain
AM371_RS09475	COG0531	amino acid
AM371_RS09480	COG1982	Orn Lys Arg decarboxylase major
AM371_RS09490	COG3787	Belongs to the UPF0306 family
AM371_RS09495	COG0702	epimerase
AM371_RS09500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM371_RS09510	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM371_RS09515	COG3454	Phosphonate metabolism
AM371_RS09520	COG4778	phosphonate C-P lyase system protein PhnL
AM371_RS09525	COG4107	phosphonate C-P lyase system protein PhnK
AM371_RS09530	COG3627	carbon phosphorus lyase activity
AM371_RS09535	COG3626	phosphonate metabolism
AM371_RS09540	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM371_RS09545	COG3624	Phosphonate C-P lyase system protein PhnG
AM371_RS09550	COG2188	Transcriptional regulator
AM371_RS09555	COG0701	Predicted permease
AM371_RS09565	COG2207	Transcriptional regulator
AM371_RS09575	COG0602	queuosine metabolic process
AM371_RS09590	COG0583	DNA-binding transcription factor activity
AM371_RS09595	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM371_RS09600	COG0366	Alpha amylase catalytic
AM371_RS09605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM371_RS09605	COG1263	PTS System
AM371_RS09615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM371_RS09620	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AM371_RS09635	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AM371_RS09640	COG0540	Belongs to the ATCase OTCase family
AM371_RS09650	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM371_RS09665	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM371_RS09670	COG0456	acetyltransferase
AM371_RS09680	COG2927	DNA polymerase III (CHI subunit)
AM371_RS09685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM371_RS09690	COG0795	lipopolysaccharide-transporting ATPase activity
AM371_RS09695	COG0795	lipopolysaccharide-transporting ATPase activity
AM371_RS09720	COG0738	Major facilitator superfamily
AM371_RS09740	COG2610	gluconate transmembrane transporter activity
AM371_RS09745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM371_RS09750	COG1349	DNA-binding transcription factor activity
AM371_RS09760	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AM371_RS09785	COG1196	nuclear chromosome segregation
AM371_RS09825	COG2723	6-phospho-beta-galactosidase activity
AM371_RS09845	COG0523	cobalamin synthesis protein
AM371_RS09850	COG2879	small protein
AM371_RS09855	COG1966	Carbon starvation protein
AM371_RS09860	COG0583	DNA-binding transcription factor activity
AM371_RS09880	COG1116	anion transmembrane transporter activity
AM371_RS09890	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM371_RS09900	COG0174	glutamine synthetase
AM371_RS09920	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AM371_RS09930	COG0583	DNA-binding transcription factor activity
AM371_RS09935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM371_RS09950	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM371_RS09955	COG2610	gluconate transmembrane transporter activity
AM371_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS09970	COG2207	Transcriptional regulator
AM371_RS09980	COG3708	Transcriptional regulator
AM371_RS09980	COG2207	Transcriptional regulator
AM371_RS09985	COG1376	ErfK ybiS ycfS ynhG family protein
AM371_RS10015	COG0811	peptide transport
AM371_RS10050	COG1454	alcohol dehydrogenase
AM371_RS10060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM371_RS10070	COG2267	carboxylic ester hydrolase activity
AM371_RS10100	COG1113	amino acid transport
AM371_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS10125	COG1846	Transcriptional regulator
AM371_RS10135	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM371_RS10145	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS10160	COG3971	2-oxopent-4-enoate hydratase activity
AM371_RS10180	COG2368	4-hydroxyphenylacetate
AM371_RS10185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM371_RS10190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM371_RS10195	COG2186	Transcriptional regulator
AM371_RS10200	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS10205	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM371_RS10210	COG4948	Mandelate Racemase Muconate Lactonizing
AM371_RS10215	COG3618	amidohydrolase
AM371_RS10225	COG3254	rhamnose metabolic process
AM371_RS10230	COG0738	Major facilitator superfamily
AM371_RS10255	COG3706	GGDEF domain
AM371_RS10285	COG0667	Aldo Keto reductase
AM371_RS10290	COG2813	Specifically methylates the guanine in position
AM371_RS10295	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM371_RS10305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM371_RS10310	COG2823	Periplasmic or secreted lipoprotein
AM371_RS10315	COG5487	UPF0391 membrane protein
AM371_RS10320	COG3237	CsbD-like
AM371_RS10325	COG4667	esterase of the alpha-beta hydrolase superfamily
AM371_RS10330	COG0084	hydrolase, TatD family'
AM371_RS10335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM371_RS10340	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM371_RS10350	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM371_RS10355	COG0813	purine-nucleoside phosphorylase activity
AM371_RS10360	COG3550	peptidyl-serine autophosphorylation
AM371_RS10365	COG3726	membrane protein affecting hemolysin expression
AM371_RS10370	COG0560	Phosphoserine phosphatase
AM371_RS10390	COG0604	alcohol dehydrogenase
AM371_RS10400	COG2130	NADP-dependent
AM371_RS10415	COG0488	(ABC) transporter
AM371_RS10420	COG2885	chlorophyll binding
AM371_RS10425	COG2199	diguanylate cyclase activity
AM371_RS10435	COG0741	lytic transglycosylase activity
AM371_RS10440	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AM371_RS10445	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AM371_RS10450	COG0406	alpha-ribazole phosphatase activity
AM371_RS10455	COG2207	Transcriptional regulator
AM371_RS10455	COG3708	Transcriptional regulator
AM371_RS10460	COG3045	CreA protein
AM371_RS10465	COG0745	RESPONSE REGULATOR receiver
AM371_RS10495	COG3022	response to hydroperoxide
AM371_RS10500	COG1115	amino acid carrier protein
AM371_RS10505	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM371_RS10510	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM371_RS10520	COG1584	GPR1 FUN34 yaaH family protein
AM371_RS10525	COG0443	Heat shock 70 kDa protein
AM371_RS10530	COG0484	heat shock protein binding
AM371_RS10535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM371_RS10540	COG0583	DNA-binding transcription factor activity
AM371_RS10545	COG0268	Binds directly to 16S ribosomal RNA
AM371_RS10555	COG0196	riboflavin kinase activity
AM371_RS10560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM371_RS10565	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM371_RS10570	COG1047	Peptidyl-prolyl cis-trans
AM371_RS10575	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AM371_RS10600	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM371_RS10605	COG0505	Belongs to the CarA family
AM371_RS10610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM371_RS10630	COG2966	Psort location CytoplasmicMembrane, score
AM371_RS10640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM371_RS10650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM371_RS10655	COG2967	ApaG domain
AM371_RS10660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM371_RS10665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM371_RS10675	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM371_RS10685	COG0564	pseudouridine synthase activity
AM371_RS10690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM371_RS10695	COG0417	DNA replication proofreading
AM371_RS10700	COG0586	Pfam SNARE associated Golgi protein
AM371_RS10705	COG0440	acetolactate synthase activity
AM371_RS10710	COG0028	Belongs to the TPP enzyme family
AM371_RS10725	COG1178	ABC-type Fe3 transport system permease component
AM371_RS10730	COG4143	(ABC) transporter
AM371_RS10745	COG2814	Major facilitator Superfamily
AM371_RS10750	COG0471	metal ion transport
AM371_RS10755	COG0066	3-isopropylmalate dehydratase activity
AM371_RS10760	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM371_RS10765	COG0473	3-isopropylmalate dehydrogenase activity
AM371_RS10770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM371_RS10780	COG0583	DNA-binding transcription factor activity
AM371_RS10785	COG1022	Amp-dependent synthetase and ligase
AM371_RS10790	COG0028	Belongs to the TPP enzyme family
AM371_RS10810	COG2001	Belongs to the MraZ family
AM371_RS10815	COG0275	rRNA processing
AM371_RS10820	COG3116	cell division
AM371_RS10825	COG0768	penicillin binding
AM371_RS10830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM371_RS10835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM371_RS10840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM371_RS10850	COG0772	Belongs to the SEDS family
AM371_RS10855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM371_RS10860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM371_RS10870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM371_RS10875	COG0849	cell division
AM371_RS10880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM371_RS10900	COG0653	protein targeting
AM371_RS10905	COG0494	nUDIX hydrolase
AM371_RS10910	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM371_RS10915	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AM371_RS10925	COG0516	GMP reductase activity
AM371_RS10930	COG1459	type II secretion system
AM371_RS10935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM371_RS10940	COG4969	Belongs to the N-Me-Phe pilin family
AM371_RS10950	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM371_RS10955	COG3725	Membrane protein required for beta-lactamase induction
AM371_RS10960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM371_RS10970	COG0316	Belongs to the HesB IscA family
AM371_RS10980	COG2860	membrane
AM371_RS10990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM371_RS10995	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AM371_RS11000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM371_RS11010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM371_RS11015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM371_RS11020	COG3956	TIGRFAM MazG family protein
AM371_RS11025	COG0504	CTP synthase activity
AM371_RS11055	COG2986	histidine ammonia-lyase
AM371_RS11060	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AM371_RS11065	COG2271	Major facilitator Superfamily
AM371_RS11070	COG0602	queuosine metabolic process
AM371_RS11075	COG0720	synthase
AM371_RS11080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM371_RS11085	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM371_RS11090	COG0175	sulfate reduction
AM371_RS11095	COG2234	aminopeptidase activity
AM371_RS11100	COG1648	precorrin-2 dehydrogenase activity
AM371_RS11100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM371_RS11105	COG0175	sulfate reduction
AM371_RS11110	COG2895	sulfate adenylyltransferase (ATP) activity
AM371_RS11130	COG0765	amino acid transport
AM371_RS11140	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AM371_RS11145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM371_RS11150	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM371_RS11155	COG0585	pseudouridine synthase activity
AM371_RS11160	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM371_RS11165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM371_RS11170	COG4942	peptidase
AM371_RS11170	COG1388	LysM domain
AM371_RS11175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM371_RS11180	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM371_RS11200	COG0667	Aldo Keto reductase
AM371_RS11215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM371_RS11220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM371_RS11225	COG2723	6-phospho-beta-galactosidase activity
AM371_RS11230	COG1917	Cupin 2, conserved barrel domain protein
AM371_RS11230	COG2169	Transcriptional regulator
AM371_RS11255	COG2137	regulation of response to DNA damage stimulus
AM371_RS11260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM371_RS11265	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM371_RS11290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM371_RS11295	COG1238	metal cluster binding
AM371_RS11300	COG2918	glutathione biosynthetic process
AM371_RS11310	COG4536	flavin adenine dinucleotide binding
AM371_RS11315	COG4137	Cytochrome C assembly protein
AM371_RS11320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM371_RS11325	COG0228	four-way junction DNA binding
AM371_RS11330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM371_RS11340	COG0335	large ribosomal subunit rRNA binding
AM371_RS11360	COG3137	Salt-induced outer membrane protein
AM371_RS11365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM371_RS11370	COG0287	Prephenate dehydrogenase
AM371_RS11370	COG1605	Chorismate mutase
AM371_RS11375	COG1605	Chorismate mutase
AM371_RS11375	COG0077	Prephenate dehydratase
AM371_RS11385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM371_RS11390	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM371_RS11400	COG0564	pseudouridine synthase activity
AM371_RS11410	COG0542	response to heat
AM371_RS11440	COG0656	L-ascorbic acid biosynthetic process
AM371_RS11445	COG0583	DNA-binding transcription factor activity
AM371_RS11450	COG3021	interspecies interaction between organisms
AM371_RS11455	COG1388	LysM domain
AM371_RS11455	COG0741	lytic transglycosylase activity
AM371_RS11460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM371_RS11465	COG2226	methyltransferase
AM371_RS11470	COG0328	RNA-DNA hybrid ribonuclease activity
AM371_RS11475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM371_RS11500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM371_RS11515	COG0436	Aminotransferase
AM371_RS11520	COG0235	Class ii aldolase
AM371_RS11525	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AM371_RS11530	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AM371_RS11535	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AM371_RS11540	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AM371_RS11550	COG1960	acyl-CoA dehydrogenase activity
AM371_RS11555	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM371_RS11560	COG0121	glutamine amidotransferase
AM371_RS11565	COG3034	peptidoglycan biosynthetic process
AM371_RS11570	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM371_RS11575	COG1805	sodium ion transport
AM371_RS11580	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM371_RS11585	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM371_RS11590	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM371_RS11595	COG2871	sodium ion transport
AM371_RS11600	COG1477	protein flavinylation
AM371_RS11605	COG2991	Protein conserved in bacteria
AM371_RS11630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM371_RS11635	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM371_RS11640	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AM371_RS11645	COG1073	alpha beta
AM371_RS11670	COG0582	viral genome integration into host DNA
AM371_RS11750	COG3188	usher protein
AM371_RS11755	COG3121	Chaperone
AM371_RS11805	COG0583	DNA-binding transcription factor activity
AM371_RS11810	COG2314	TM2 domain
AM371_RS11840	COG3038	cytochrome b561
AM371_RS11845	COG0747	negative chemotaxis
AM371_RS11850	COG1733	regulation of RNA biosynthetic process
AM371_RS11855	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM371_RS11870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM371_RS11875	COG2207	Transcriptional regulator
AM371_RS11880	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS11890	COG2169	Transcriptional regulator
AM371_RS11890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM371_RS11910	COG3961	Belongs to the TPP enzyme family
AM371_RS11940	COG1349	DNA-binding transcription factor activity
AM371_RS11945	COG0346	lactoylglutathione lyase activity
AM371_RS11960	COG1335	isochorismatase
AM371_RS11975	COG3011	Protein conserved in bacteria
AM371_RS11985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM371_RS11990	COG3416	Protein conserved in bacteria
AM371_RS12000	COG2226	methyltransferase
AM371_RS12045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM371_RS12065	COG1595	DNA-templated transcription, initiation
AM371_RS12115	COG4126	flavin adenine dinucleotide binding
AM371_RS12120	COG3123	guanosine phosphorylase activity
AM371_RS12125	COG2974	May be involved in recombination
AM371_RS12130	COG1940	carbohydrate kinase activity
AM371_RS12150	COG0419	ATPase involved in DNA repair
AM371_RS12155	COG0420	3'-5' exonuclease activity
AM371_RS12160	COG0745	RESPONSE REGULATOR receiver
AM371_RS12165	COG5002	protein histidine kinase activity
AM371_RS12190	COG0668	transmembrane transport
AM371_RS12195	COG0366	Alpha amylase catalytic
AM371_RS12205	COG0450	alkyl hydroperoxide reductase
AM371_RS12210	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AM371_RS12215	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM371_RS12220	COG0343	queuine tRNA-ribosyltransferase activity
AM371_RS12225	COG1862	Preprotein translocase
AM371_RS12235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM371_RS12240	COG4238	major outer membrane lipoprotein
AM371_RS12245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM371_RS12250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM371_RS12250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM371_RS12255	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM371_RS12260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM371_RS12265	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM371_RS12270	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM371_RS12275	COG0667	Aldo Keto reductase
AM371_RS12280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM371_RS12285	COG0142	geranyltranstransferase activity
AM371_RS12290	COG1722	exodeoxyribonuclease VII activity
AM371_RS12295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM371_RS12295	COG0301	tRNA thio-modification
AM371_RS12300	COG3210	domain, Protein
AM371_RS12305	COG2831	hemolysin activation secretion protein
AM371_RS12310	COG0693	protein deglycase activity
AM371_RS12315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM371_RS12320	COG1666	GTP binding
AM371_RS12325	COG2814	Major facilitator Superfamily
AM371_RS12330	COG0109	protoheme IX farnesyltransferase activity
AM371_RS12335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM371_RS12340	COG1845	cytochrome c oxidase, subunit III
AM371_RS12345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM371_RS12350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM371_RS12355	COG2223	nitrite transmembrane transporter activity
AM371_RS12360	COG3056	Lipoprotein
AM371_RS12365	COG0271	Belongs to the BolA IbaG family
AM371_RS12370	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM371_RS12380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM371_RS12385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM371_RS12395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM371_RS12400	COG1555	photosystem II stabilization
AM371_RS12405	COG0824	Thioesterase
AM371_RS12410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM371_RS12415	COG4533	DNA binding
AM371_RS12420	COG0561	phosphatase activity
AM371_RS12430	COG1522	sequence-specific DNA binding
AM371_RS12435	COG1132	(ABC) transporter
AM371_RS12440	COG1132	(ABC) transporter
AM371_RS12445	COG0347	Belongs to the P(II) protein family
AM371_RS12450	COG0004	ammonium transporteR
AM371_RS12455	COG1946	Acyl-CoA thioesterase
AM371_RS12460	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM371_RS12465	COG3695	enzyme binding
AM371_RS12500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM371_RS12555	COG3397	chitin binding
AM371_RS12580	COG1121	(ABC) transporter
AM371_RS12585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM371_RS12590	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM371_RS12595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM371_RS12600	COG0254	rRNA binding
AM371_RS12605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM371_RS12610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM371_RS12615	COG1309	transcriptional regulator
AM371_RS12620	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM371_RS12635	COG2832	Protein of unknown function (DUF454)
AM371_RS12640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM371_RS12645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM371_RS12655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM371_RS12660	COG0326	Molecular chaperone. Has ATPase activity
AM371_RS12670	COG0563	adenylate kinase activity
AM371_RS12675	COG3835	regulator
AM371_RS12680	COG2610	gluconate transmembrane transporter activity
AM371_RS12685	COG1929	Belongs to the glycerate kinase type-1 family
AM371_RS12690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM371_RS12695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM371_RS12700	COG4651	solute:proton antiporter activity
AM371_RS12700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM371_RS12705	COG2223	nitrite transmembrane transporter activity
AM371_RS12710	COG0737	Belongs to the 5'-nucleotidase family
AM371_RS12720	COG2814	Major facilitator Superfamily
AM371_RS12730	COG3483	tryptophan 2,3-dioxygenase activity
AM371_RS12755	COG2027	D-alanyl-D-alanine carboxypeptidase
AM371_RS12760	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM371_RS12765	COG3735	TraB family
AM371_RS12770	COG2217	Heavy metal translocating P-type atpase
AM371_RS12775	COG0789	Transcriptional regulator
AM371_RS12780	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM371_RS12785	COG0330	HflC and HflK could
AM371_RS12790	COG0583	DNA-binding transcription factor activity
AM371_RS12805	COG3960	tartronate-semialdehyde synthase activity
AM371_RS12810	COG3622	Belongs to the hyi family
AM371_RS12815	COG2084	Dehydrogenase
AM371_RS12820	COG2271	Major facilitator Superfamily
AM371_RS12825	COG1929	Belongs to the glycerate kinase type-1 family
AM371_RS12830	COG3257	ureidoglycine aminohydrolase activity
AM371_RS12840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM371_RS12845	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM371_RS12850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM371_RS12855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM371_RS12865	COG0549	Belongs to the carbamate kinase family
AM371_RS12870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM371_RS12875	COG3118	belongs to the thioredoxin family
AM371_RS12880	COG0300	oxidoreductase activity
AM371_RS12885	COG2755	lipolytic protein G-D-S-L family
AM371_RS12890	COG4181	ATPase activity
AM371_RS12895	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM371_RS12900	COG2814	Major facilitator Superfamily
AM371_RS12905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM371_RS12910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM371_RS12915	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM371_RS12920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM371_RS12925	COG0215	cysteine-tRNA ligase activity
AM371_RS12930	COG2501	S4 domain
AM371_RS12935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM371_RS12970	COG2199	diguanylate cyclase activity
AM371_RS12975	COG1278	Cold shock
AM371_RS12985	COG1126	abc transporter atp-binding protein
AM371_RS12990	COG0765	amino acid transport
AM371_RS13005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM371_RS13010	COG1473	amidohydrolase
AM371_RS13020	COG2814	Major facilitator Superfamily
AM371_RS13025	COG1309	transcriptional regulator
AM371_RS13030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM371_RS13035	COG3706	GGDEF domain
AM371_RS13045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM371_RS13050	COG0321	lipoyl(octanoyl) transferase activity
AM371_RS13060	COG1686	Belongs to the peptidase S11 family
AM371_RS13065	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM371_RS13070	COG0772	Belongs to the SEDS family
AM371_RS13075	COG0768	penicillin binding
AM371_RS13080	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AM371_RS13085	COG0799	negative regulation of ribosome biogenesis
AM371_RS13090	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM371_RS13095	COG1466	dna polymerase III delta subunit
AM371_RS13100	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AM371_RS13105	COG0495	leucyl-tRNA aminoacylation
AM371_RS13110	COG2888	peptidyl-tyrosine sulfation
AM371_RS13120	COG1957	nucleoside hydrolase
AM371_RS13130	COG1126	abc transporter atp-binding protein
AM371_RS13135	COG0765	amino acid transport
AM371_RS13140	COG0765	amino acid transport
AM371_RS13150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM371_RS13155	COG4535	Mg2 and Co2 transporter CorC
AM371_RS13160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM371_RS13165	COG1702	phosphate starvation-inducible protein PhoH
AM371_RS13170	COG2824	Alkylphosphonate utilization operon protein PhnA
AM371_RS13175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM371_RS13180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM371_RS13215	COG0367	asparagine synthase
AM371_RS13220	COG3469	chitinase activity
AM371_RS13225	COG0647	UMP catabolic process
AM371_RS13230	COG1940	carbohydrate kinase activity
AM371_RS13230	COG1846	Transcriptional regulator
AM371_RS13235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM371_RS13240	COG0363	glucosamine-6-phosphate deaminase activity
AM371_RS13245	COG1263	PTS System
AM371_RS13245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM371_RS13245	COG2190	(PTS) system
AM371_RS13250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM371_RS13270	COG0735	belongs to the Fur family
AM371_RS13285	COG0596	Alpha beta hydrolase
AM371_RS13290	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AM371_RS13295	COG0033	Phosphoglucomutase
AM371_RS13300	COG1695	Transcriptional regulator
AM371_RS13310	COG0745	RESPONSE REGULATOR receiver
AM371_RS13315	COG2205	protein histidine kinase activity
AM371_RS13320	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AM371_RS13325	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM371_RS13330	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM371_RS13345	COG3272	Protein of unknown function (DUF1722)
AM371_RS13355	COG5212	phosphodiesterase
AM371_RS13360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM371_RS13365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM371_RS13370	COG1984	allophanate hydrolase subunit 2
AM371_RS13375	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AM371_RS13410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM371_RS13415	COG1053	succinate dehydrogenase
AM371_RS13420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM371_RS13425	COG0567	Dehydrogenase, E1 component
AM371_RS13430	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM371_RS13435	COG0045	succinate-CoA ligase (ADP-forming) activity
AM371_RS13440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM371_RS13445	COG0737	Belongs to the 5'-nucleotidase family
AM371_RS13450	COG1271	oxidase subunit
AM371_RS13455	COG1294	oxidase, subunit
AM371_RS13460	COG4890	Cyd operon protein YbgT
AM371_RS13465	COG3790	cyd operon protein YbgE
AM371_RS13470	COG0824	Thioesterase
AM371_RS13475	COG0811	peptide transport
AM371_RS13480	COG0848	biopolymer transport protein
AM371_RS13485	COG3064	Membrane
AM371_RS13485	COG3064	Membrane
AM371_RS13490	COG0823	Involved in the tonB-independent uptake of proteins
AM371_RS13495	COG2885	chlorophyll binding
AM371_RS13500	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM371_RS13540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM371_RS13550	COG1230	cation diffusion facilitator family transporter
AM371_RS13555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM371_RS13555	COG2205	protein histidine kinase activity
AM371_RS13560	COG2197	response regulator
AM371_RS13565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM371_RS13580	COG0588	phosphoglycerate mutase activity
AM371_RS13590	COG2017	converts alpha-aldose to the beta-anomer
AM371_RS13595	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AM371_RS13600	COG1085	galactose-1-phosphate uridylyltransferase
AM371_RS13615	COG1119	ATPase activity
AM371_RS13620	COG3585	molybdate ion transport
AM371_RS13620	COG2005	Transcriptional regulator
AM371_RS13625	COG4774	siderophore transport
AM371_RS13635	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM371_RS13640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM371_RS13645	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM371_RS13655	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM371_RS13660	COG4149	molybdate abc transporter
AM371_RS13670	COG0561	phosphatase activity
AM371_RS13675	COG2706	6-phosphogluconolactonase activity
AM371_RS13680	COG1881	PFAM PEBP family protein
AM371_RS13720	COG0556	nucleotide-excision repair
AM371_RS13725	COG4628	conserved protein (DUF2132)
AM371_RS13730	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM371_RS13735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM371_RS13740	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM371_RS13745	COG0315	cyclic pyranopterin monophosphate synthase activity
AM371_RS13750	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM371_RS13755	COG0314	molybdopterin synthase activity
AM371_RS13760	COG0670	Belongs to the BI1 family
AM371_RS13765	COG0842	Transport permease protein
AM371_RS13770	COG0842	Transport permease protein
AM371_RS13775	COG1131	(ABC) transporter
AM371_RS13780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM371_RS13785	COG1309	transcriptional regulator
AM371_RS13790	COG0513	Belongs to the DEAD box helicase family
AM371_RS13795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM371_RS13800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM371_RS13810	COG3842	ATPase activity
AM371_RS13820	COG1840	ABC-type Fe3 transport system, periplasmic component
AM371_RS13825	COG2271	Major facilitator Superfamily
AM371_RS13845	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS13850	COG0583	DNA-binding transcription factor activity
AM371_RS13870	COG0583	DNA-binding transcription factor activity
AM371_RS13875	COG0586	Pfam SNARE associated Golgi protein
AM371_RS13885	COG4977	sequence-specific DNA binding
AM371_RS13890	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM371_RS13895	COG1686	Belongs to the peptidase S11 family
AM371_RS13915	COG2354	Protein conserved in bacteria
AM371_RS13925	COG1464	Belongs to the NlpA lipoprotein family
AM371_RS13935	COG0456	acetyltransferase
AM371_RS13955	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM371_RS13965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM371_RS13970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM371_RS13975	COG0840	transmembrane signaling receptor activity
AM371_RS13980	COG0277	FAD linked oxidase domain protein
AM371_RS13995	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM371_RS14005	COG0436	Aminotransferase
AM371_RS14015	COG1472	Belongs to the glycosyl hydrolase 3 family
AM371_RS14035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM371_RS14040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM371_RS14045	COG1120	ATPase activity
AM371_RS14055	COG0596	Alpha beta hydrolase
AM371_RS14060	COG2134	cdp-diacylglycerol pyrophosphatase
AM371_RS14090	COG1192	Involved in chromosome partitioning
AM371_RS14100	COG0583	DNA-binding transcription factor activity
AM371_RS14110	COG1070	Carbohydrate kinase
AM371_RS14115	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM371_RS14120	COG0697	spore germination
AM371_RS14175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM371_RS14190	COG1309	transcriptional regulator
AM371_RS14195	COG1464	Belongs to the NlpA lipoprotein family
AM371_RS14200	COG2011	ABC-type metal ion transport system permease component
AM371_RS14205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM371_RS14210	COG0519	Catalyzes the synthesis of GMP from XMP
AM371_RS14230	COG2084	Dehydrogenase
AM371_RS14245	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM371_RS14260	COG4807	Protein conserved in bacteria
AM371_RS14280	COG1802	Transcriptional regulator
AM371_RS14300	COG0411	ABC transporter
AM371_RS14340	COG0583	DNA-binding transcription factor activity
AM371_RS14345	COG2897	thiosulfate sulfurtransferase activity
AM371_RS14350	COG0494	nUDIX hydrolase
AM371_RS14355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM371_RS14365	COG0625	glutathione transferase activity
AM371_RS14375	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AM371_RS14385	COG1335	isochorismatase
AM371_RS14390	COG0583	DNA-binding transcription factor activity
AM371_RS14405	COG1732	Glycine betaine
AM371_RS14410	COG1174	glycine betaine transport
AM371_RS14415	COG1125	glycine betaine transport
AM371_RS14420	COG1174	glycine betaine transport
AM371_RS14440	COG0697	spore germination
AM371_RS14475	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AM371_RS14490	COG0625	glutathione transferase activity
AM371_RS14495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM371_RS14500	COG1942	4-Oxalocrotonate Tautomerase
AM371_RS14510	COG1522	sequence-specific DNA binding
AM371_RS14515	COG0697	spore germination
AM371_RS14535	COG2079	MmgE PrpD family protein
AM371_RS14540	COG1280	lysine exporter protein (LysE YggA)
AM371_RS14550	COG0477	Major facilitator Superfamily
AM371_RS14560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM371_RS14580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM371_RS14585	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AM371_RS14600	COG0668	transmembrane transport
AM371_RS14605	COG1126	abc transporter atp-binding protein
AM371_RS14610	COG0765	amino acid transport
AM371_RS14615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM371_RS14620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM371_RS14635	COG2731	YhcH YjgK YiaL family protein
AM371_RS14645	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM371_RS14650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM371_RS14665	COG2610	gluconate transmembrane transporter activity
AM371_RS14670	COG3622	Belongs to the hyi family
AM371_RS14675	COG0235	Class ii aldolase
AM371_RS14680	COG3395	kinase activity
AM371_RS14685	COG2084	Dehydrogenase
AM371_RS14690	COG1349	DNA-binding transcription factor activity
AM371_RS14700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM371_RS14705	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM371_RS14745	COG3188	usher protein
AM371_RS14760	COG5002	protein histidine kinase activity
AM371_RS14765	COG0745	RESPONSE REGULATOR receiver
AM371_RS14770	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM371_RS14775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM371_RS14790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM371_RS14795	COG1309	transcriptional regulator
AM371_RS14800	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS14805	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM371_RS14810	COG0069	glutamate synthase activity
AM371_RS14820	COG2200	EAL domain
AM371_RS14830	COG3121	Chaperone
AM371_RS14835	COG3188	usher protein
AM371_RS14845	COG3708	Transcriptional regulator
AM371_RS14845	COG2207	Transcriptional regulator
AM371_RS14850	COG0579	oxidoreductase
AM371_RS14860	COG0625	glutathione transferase activity
AM371_RS14865	COG0640	Transcriptional regulator
AM371_RS14875	COG1335	isochorismatase
AM371_RS14880	COG0583	DNA-binding transcription factor activity
AM371_RS14895	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AM371_RS14905	COG0583	DNA-binding transcription factor activity
AM371_RS14915	COG0488	(ABC) transporter
AM371_RS14920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM371_RS14925	COG0303	'Molybdopterin
AM371_RS14940	COG4172	Belongs to the ABC transporter superfamily
AM371_RS14945	COG0747	negative chemotaxis
AM371_RS14950	COG0601	transmembrane transport
AM371_RS14955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM371_RS14980	COG0583	DNA-binding transcription factor activity
AM371_RS14985	COG0477	Major facilitator Superfamily
AM371_RS14990	COG0302	gtp cyclohydrolase
AM371_RS14995	COG2311	Membrane
AM371_RS15000	COG1609	Transcriptional regulator
AM371_RS15020	COG2949	membrane
AM371_RS15025	COG0281	malic enzyme
AM371_RS15030	COG0295	cytidine deaminase activity
AM371_RS15035	COG1346	cytolysis
AM371_RS15040	COG1380	Effector of murein hydrolase LrgA
AM371_RS15045	COG2814	Major facilitator Superfamily
AM371_RS15055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM371_RS15055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM371_RS15060	COG0489	protein tyrosine kinase activity
AM371_RS15070	COG0572	uridine kinase
AM371_RS15075	COG0717	Belongs to the dCTP deaminase family
AM371_RS15080	COG2982	Protein involved in outer membrane biogenesis
AM371_RS15085	COG3069	C4-dicarboxylate transmembrane transporter activity
AM371_RS15090	COG1253	flavin adenine dinucleotide binding
AM371_RS15095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM371_RS15110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM371_RS15115	COG0489	protein tyrosine kinase activity
AM371_RS15115	COG3206	protein involved in exopolysaccharide biosynthesis
AM371_RS15120	COG1083	cytidylyl-transferase
AM371_RS15125	COG2089	acid synthase
AM371_RS15130	COG2244	polysaccharide biosynthetic process
AM371_RS15135	COG0110	maltose O-acetyltransferase activity
AM371_RS15225	COG1091	dTDP-4-dehydrorhamnose reductase activity
AM371_RS15265	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM371_RS15270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM371_RS15270	COG0140	phosphoribosyl-ATP diphosphatase activity
AM371_RS15275	COG0107	imidazoleglycerol-phosphate synthase activity
AM371_RS15280	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM371_RS15295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM371_RS15300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM371_RS15305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM371_RS15315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM371_RS15330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM371_RS15335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM371_RS15335	COG3153	acetyltransferase
AM371_RS15340	COG0598	Magnesium transport protein CorA
AM371_RS15350	COG2133	pyrroloquinoline quinone binding
AM371_RS15355	COG0625	glutathione transferase activity
AM371_RS15370	COG0626	cystathionine gamma-synthase activity
AM371_RS15380	COG1686	Belongs to the peptidase S11 family
AM371_RS15405	COG3539	Fimbrial protein
AM371_RS15410	COG3188	usher protein
AM371_RS15415	COG3121	Chaperone
AM371_RS15435	COG0545	Peptidyl-prolyl cis-trans isomerase
AM371_RS15440	COG2197	response regulator
AM371_RS15445	COG1760	l-serine dehydratase
AM371_RS15450	COG0814	amino acid
AM371_RS15455	COG1349	DNA-binding transcription factor activity
AM371_RS15460	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM371_RS15470	COG0671	phosphoesterase, PA-phosphatase related
AM371_RS15485	COG4574	serine-type endopeptidase inhibitor activity
AM371_RS15495	COG3395	kinase activity
AM371_RS15500	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM371_RS15520	COG0666	response to abiotic stimulus
AM371_RS15525	COG1595	DNA-templated transcription, initiation
AM371_RS15530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM371_RS15540	COG0569	domain protein
AM371_RS15540	COG2985	domain, Protein
AM371_RS15560	COG0189	ligase activity
AM371_RS15570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM371_RS15575	COG3842	ATPase activity
AM371_RS15580	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM371_RS15585	COG1177	transmembrane transport
AM371_RS15595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM371_RS15600	COG2026	Addiction module toxin, RelE StbE family
AM371_RS15610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM371_RS15615	COG4160	amino acid transport
AM371_RS15620	COG4215	(ABC) transporter
AM371_RS15625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM371_RS15630	COG1126	abc transporter atp-binding protein
AM371_RS15640	COG0393	Putative heavy-metal-binding
AM371_RS15645	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM371_RS15650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM371_RS15655	COG0702	epimerase
AM371_RS15665	COG1737	Transcriptional regulator
AM371_RS15670	COG2190	(PTS) system
AM371_RS15670	COG1263	PTS System
AM371_RS15670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM371_RS15675	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AM371_RS15680	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM371_RS15685	COG0028	Belongs to the TPP enzyme family
AM371_RS15690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM371_RS15695	COG1151	hydroxylamine reductase activity
AM371_RS15700	COG2431	L-lysine efflux transmembrane transporter activity
AM371_RS15705	COG3593	DNA synthesis involved in DNA repair
AM371_RS15710	COG2990	Protein conserved in bacteria
AM371_RS15715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM371_RS15725	COG1278	Cold shock
AM371_RS15730	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM371_RS15735	COG0542	response to heat
AM371_RS15740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM371_RS15745	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM371_RS15750	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM371_RS15760	COG0492	ferredoxin-NADP+ reductase activity
AM371_RS15770	COG1674	ftsk spoiiie
AM371_RS15770	COG3107	peptidoglycan biosynthetic process
AM371_RS15775	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM371_RS15780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM371_RS15785	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM371_RS15795	COG2814	Major facilitator Superfamily
AM371_RS15800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM371_RS15805	COG1882	Formate acetyltransferase
AM371_RS15810	COG2116	formate transmembrane transporter activity
AM371_RS15815	COG1944	ATP diphosphatase activity
AM371_RS15830	COG0252	asparaginase activity
AM371_RS15835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AM371_RS15840	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM371_RS15845	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM371_RS15850	COG0539	negative regulation of cytoplasmic translation
AM371_RS15860	COG0658	competence protein
AM371_RS15860	COG2333	competence protein COMEC
AM371_RS15865	COG1132	(ABC) transporter
AM371_RS15870	COG1663	tetraacyldisaccharide 4'-kinase activity
AM371_RS15875	COG5383	Protein conserved in bacteria
AM371_RS15885	COG1278	Cold shock
AM371_RS15890	COG3214	Protein conserved in bacteria
AM371_RS15895	COG2835	tetraacyldisaccharide 4'-kinase activity
AM371_RS15900	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM371_RS15905	COG3173	Aminoglycoside phosphotransferase
AM371_RS15910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM371_RS15915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM371_RS15920	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AM371_RS15930	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM371_RS15935	COG2989	Protein conserved in bacteria
AM371_RS15940	COG3108	Peptidase M15
AM371_RS15945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM371_RS15950	COG1448	Aminotransferase
AM371_RS15965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AM371_RS15970	COG3706	GGDEF domain
AM371_RS15975	COG0308	aminopeptidase N
AM371_RS15985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM371_RS15990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM371_RS15995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM371_RS16000	COG0431	NADPH-dependent FMN reductase
AM371_RS16005	COG0167	dihydroorotate dehydrogenase activity
AM371_RS16015	COG3217	Mosc domain protein beta barrel domain protein
AM371_RS16015	COG0633	Ferredoxin
AM371_RS16020	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM371_RS16020	COG0116	Belongs to the methyltransferase superfamily
AM371_RS16025	COG0488	(ABC) transporter
AM371_RS16030	COG2995	paraquat-inducible protein a
AM371_RS16035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM371_RS16035	COG3008	intermembrane lipid transfer
AM371_RS16040	COG3009	Protein conserved in bacteria
AM371_RS16045	COG3130	regulation of translation
AM371_RS16050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM371_RS16060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM371_RS16065	COG1067	ATP-dependent peptidase activity
AM371_RS16085	COG3070	regulator of competence-specific genes
AM371_RS16090	COG1289	transmembrane transporter activity
AM371_RS16095	COG3304	Inner membrane component domain
AM371_RS16100	COG0210	DNA helicase
AM371_RS16105	COG1803	Methylglyoxal synthase
AM371_RS16115	COG1832	CoA-binding protein
AM371_RS16120	COG3785	DNA binding
AM371_RS16125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM371_RS16135	COG3594	Acyltransferase
AM371_RS16140	COG1254	Belongs to the acylphosphatase family
AM371_RS16145	COG2920	part of a sulfur-relay system
AM371_RS16150	COG0670	Belongs to the BI1 family
AM371_RS16175	COG2197	response regulator
AM371_RS16185	COG3121	Chaperone
AM371_RS16190	COG3188	usher protein
AM371_RS16210	COG0789	Transcriptional regulator
AM371_RS16220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM371_RS16225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM371_RS16235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM371_RS16245	COG0655	NAD(P)H dehydrogenase (quinone) activity
AM371_RS16260	COG1113	amino acid transport
AM371_RS16270	COG0586	Pfam SNARE associated Golgi protein
AM371_RS16275	COG2271	Major facilitator Superfamily
AM371_RS16300	COG2814	Major facilitator Superfamily
AM371_RS16305	COG0156	8-amino-7-oxononanoate synthase activity
AM371_RS16310	COG0183	Belongs to the thiolase family
AM371_RS16315	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM371_RS16320	COG2197	response regulator
AM371_RS16325	COG0589	response to stress
AM371_RS16340	COG0531	amino acid
AM371_RS16345	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS16350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM371_RS16375	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM371_RS16390	COG3136	membrane protein required for alginate biosynthesis
AM371_RS16400	COG2197	response regulator
AM371_RS16405	COG0322	excinuclease ABC activity
AM371_RS16490	COG1846	Transcriptional regulator
AM371_RS16505	COG1403	HNH endonuclease
AM371_RS16535	COG3772	lysozyme
AM371_RS16570	COG0740	serine-type endopeptidase activity
AM371_RS16645	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM371_RS16660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM371_RS16665	COG2135	peptidase activity
AM371_RS16675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM371_RS16710	COG1538	Outer membrane efflux protein
AM371_RS16720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM371_RS16725	COG0322	excinuclease ABC activity
AM371_RS16765	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AM371_RS16770	COG2943	transferase activity, transferring hexosyl groups
AM371_RS16775	COG5645	(Lipo)protein
AM371_RS16790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM371_RS16800	COG0640	Transcriptional regulator
AM371_RS16815	COG0346	lactoylglutathione lyase activity
AM371_RS16825	COG2814	Major facilitator Superfamily
AM371_RS16835	COG1560	Kdo2-lipid A biosynthetic process
AM371_RS16845	COG1054	Belongs to the UPF0176 family
AM371_RS16850	COG2353	YceI-like domain
AM371_RS16855	COG3038	cytochrome b561
AM371_RS16860	COG0628	permease
AM371_RS16900	COG0418	dihydroorotase activity
AM371_RS16905	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM371_RS16910	COG1530	ribonuclease E activity
AM371_RS16920	COG0564	pseudouridine synthase activity
AM371_RS16930	COG1399	metal-binding, possibly nucleic acid-binding protein
AM371_RS16935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM371_RS16940	COG0416	fatty acid biosynthetic process
AM371_RS16945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM371_RS16950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM371_RS16960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM371_RS16965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM371_RS16970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM371_RS16975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM371_RS16980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM371_RS16985	COG0470	DNA polymerase III
AM371_RS16990	COG0084	hydrolase, TatD family'
AM371_RS16995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM371_RS16995	COG1263	PTS System
AM371_RS17005	COG1321	iron dependent repressor
AM371_RS17010	COG1914	H( )-stimulated, divalent metal cation uptake system
AM371_RS17015	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS17020	COG1733	regulation of RNA biosynthetic process
AM371_RS17030	COG0537	adenosine 5'-monophosphoramidase activity
AM371_RS17035	COG5633	Lipoprotein
AM371_RS17040	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AM371_RS17055	COG3150	esterase
AM371_RS17060	COG1252	NADH dehydrogenase
AM371_RS17065	COG3134	Outer membrane lipoprotein
AM371_RS17080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM371_RS17085	COG2207	Transcriptional regulator
AM371_RS17085	COG3708	Transcriptional regulator
AM371_RS17115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM371_RS17120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AM371_RS17125	COG3381	protein complex oligomerization
AM371_RS17130	COG2979	Protein of unknown function (DUF533)
AM371_RS17135	COG1770	oligopeptidase
AM371_RS17140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM371_RS17160	COG1528	Iron-storage protein
AM371_RS17165	COG2372	response to copper ion
AM371_RS17170	COG1276	copper resistance
AM371_RS17195	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM371_RS17215	COG4565	transcriptional regulatory protein
AM371_RS17220	COG3290	protein histidine kinase activity
AM371_RS17235	COG1129	ABC transporter
AM371_RS17240	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS17255	COG0579	oxidoreductase
AM371_RS17270	COG2358	TRAP transporter, solute receptor (TAXI family
AM371_RS17275	COG1464	Belongs to the NlpA lipoprotein family
AM371_RS17285	COG0589	response to stress
AM371_RS17290	COG3408	Glycogen debranching enzyme
AM371_RS17290	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AM371_RS17300	COG1609	Transcriptional regulator
AM371_RS17305	COG3250	beta-galactosidase activity
AM371_RS17310	COG2731	YhcH YjgK YiaL family protein
AM371_RS17315	COG0531	amino acid
AM371_RS17320	COG0640	Transcriptional regulator
AM371_RS17330	COG0740	serine-type endopeptidase activity
AM371_RS17355	COG3121	Chaperone
AM371_RS17395	COG0012	GTP binding
AM371_RS17400	COG0659	secondary active sulfate transmembrane transporter activity
AM371_RS17405	COG0193	aminoacyl-tRNA hydrolase activity
AM371_RS17415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM371_RS17420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM371_RS17425	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM371_RS17430	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM371_RS17435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM371_RS17440	COG2890	protein-(glutamine-N5) methyltransferase activity
AM371_RS17445	COG3094	Invasion gene expression up-regulator, SirB
AM371_RS17450	COG2912	Transglutaminase-like superfamily
AM371_RS17455	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM371_RS17460	COG0659	secondary active sulfate transmembrane transporter activity
AM371_RS17465	COG4702	Belongs to the UPF0303 family
AM371_RS17470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM371_RS17480	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM371_RS17490	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM371_RS17515	COG1486	melibiose metabolic process
AM371_RS17520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM371_RS17520	COG1263	PTS System
AM371_RS17525	COG1177	transmembrane transport
AM371_RS17540	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM371_RS17560	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM371_RS17565	COG2850	peptidyl-arginine hydroxylation
AM371_RS17575	COG0745	RESPONSE REGULATOR receiver
AM371_RS17580	COG1397	ADP-ribosylglycohydrolase
AM371_RS17585	COG2188	Transcriptional regulator
AM371_RS17600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM371_RS17605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM371_RS17610	COG2915	High frequency lysogenization protein hflD homolog
AM371_RS17620	COG0482	sulfurtransferase activity
AM371_RS17635	COG1187	pseudouridine synthase activity
AM371_RS17640	COG0538	isocitrate dehydrogenase activity
AM371_RS17660	COG3064	Membrane
AM371_RS17720	COG1278	Cold shock
AM371_RS17730	COG1335	isochorismatase
AM371_RS17735	COG0589	response to stress
AM371_RS17740	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS17745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM371_RS17750	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS17755	COG1396	sequence-specific DNA binding
AM371_RS17755	COG1917	Cupin 2, conserved barrel domain protein
AM371_RS17760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM371_RS17765	COG0174	glutamine synthetase
AM371_RS17775	COG0531	amino acid
AM371_RS17805	COG1605	Chorismate mutase
AM371_RS17820	COG1228	amidohydrolase
AM371_RS17830	COG0402	S-adenosylhomocysteine deaminase activity
AM371_RS17850	COG2211	Major facilitator Superfamily
AM371_RS17855	COG0477	Major facilitator Superfamily
AM371_RS17860	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AM371_RS17865	COG3493	citrate carrier protein
AM371_RS17925	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AM371_RS17925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM371_RS17930	COG3008	intermembrane lipid transfer
AM371_RS17935	COG2995	paraquat-inducible protein a
AM371_RS17940	COG1956	GAF domain-containing protein
AM371_RS17945	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM371_RS17950	COG0793	Belongs to the peptidase S41A family
AM371_RS17955	COG0501	Belongs to the peptidase M48B family
AM371_RS17965	COG2814	Major facilitator Superfamily
AM371_RS17995	COG2188	Transcriptional regulator
AM371_RS18010	COG1823	symporter activity
AM371_RS18015	COG1988	membrane-bound metal-dependent
AM371_RS18020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM371_RS18035	COG3001	Fructosamine kinase
AM371_RS18040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM371_RS18045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM371_RS18050	COG1121	(ABC) transporter
AM371_RS18055	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM371_RS18085	COG0814	amino acid
AM371_RS18110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM371_RS18120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM371_RS18125	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM371_RS18130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM371_RS18150	COG4139	cobalamin transport
AM371_RS18155	COG0386	Belongs to the glutathione peroxidase family
AM371_RS18165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM371_RS18170	COG1215	transferase activity, transferring glycosyl groups
AM371_RS18175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM371_RS18175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM371_RS18180	COG0726	polysaccharide deacetylase
AM371_RS18185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM371_RS18190	COG2076	Multidrug Resistance protein
AM371_RS18195	COG2076	Multidrug Resistance protein
AM371_RS18200	COG0791	NLP P60 protein
AM371_RS18205	COG0095	Lipoate-protein ligase
AM371_RS18225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM371_RS18230	COG4558	Periplasmic binding protein
AM371_RS18235	COG3720	iron ion transport
AM371_RS18250	COG0386	Belongs to the glutathione peroxidase family
AM371_RS18255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM371_RS18260	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AM371_RS18270	COG0574	Belongs to the PEP-utilizing enzyme family
AM371_RS18270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM371_RS18280	COG0628	permease
AM371_RS18285	COG0247	lactate metabolic process
AM371_RS18285	COG0277	FAD linked oxidase domain protein
AM371_RS18290	COG2050	protein possibly involved in aromatic compounds catabolism
AM371_RS18300	COG0316	Belongs to the HesB IscA family
AM371_RS18305	COG0719	Fe-S assembly protein
AM371_RS18310	COG0396	ATPase activity
AM371_RS18315	COG0719	Fe-S assembly protein
AM371_RS18320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM371_RS18325	COG2166	iron-sulfur cluster assembly
AM371_RS18330	COG1388	LysM domain
AM371_RS18330	COG1376	ErfK ybiS ycfS ynhG family protein
AM371_RS18340	COG0469	pyruvate kinase activity
AM371_RS18365	COG0534	Mate efflux family protein
AM371_RS18370	COG0307	riboflavin synthase, alpha
AM371_RS18380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM371_RS18385	COG2814	Major facilitator Superfamily
AM371_RS18390	COG0583	DNA-binding transcription factor activity
AM371_RS18395	COG1609	Transcriptional regulator
AM371_RS18410	COG0791	NLP P60 protein
AM371_RS18415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM371_RS18425	COG0346	lactoylglutathione lyase activity
AM371_RS18430	COG1902	pentaerythritol trinitrate reductase activity
AM371_RS18435	COG1309	transcriptional regulator
AM371_RS18440	COG2194	sulfuric ester hydrolase activity
AM371_RS18450	COG0583	DNA-binding transcription factor activity
AM371_RS18455	COG3313	Fe-S protein
AM371_RS18460	COG4989	oxidoreductase activity
AM371_RS18465	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM371_RS18475	COG1289	transmembrane transporter activity
AM371_RS18480	COG1566	PFAM secretion protein HlyD family protein
AM371_RS18490	COG1846	Transcriptional regulator
AM371_RS18495	COG3133	Outer membrane lipoprotein
AM371_RS18500	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM371_RS18510	COG0259	pyridoxamine-phosphate oxidase activity
AM371_RS18515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM371_RS18530	COG0625	glutathione transferase activity
AM371_RS18545	COG1418	mRNA catabolic process
AM371_RS18580	COG3135	benzoate transporter
AM371_RS18585	COG1396	sequence-specific DNA binding
AM371_RS18590	COG1505	serine-type exopeptidase activity
AM371_RS18595	COG3104	oligopeptide transport
AM371_RS18600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM371_RS18610	COG4659	FMN binding
AM371_RS18620	COG2207	Transcriptional regulator
AM371_RS18620	COG3708	Transcriptional regulator
AM371_RS18625	COG4656	Part of a membrane complex involved in electron transport
AM371_RS18630	COG2878	Part of a membrane complex involved in electron transport
AM371_RS18635	COG4657	Part of a membrane complex involved in electron transport
AM371_RS18645	COG0673	inositol 2-dehydrogenase activity
AM371_RS18650	COG0385	Bile acid
AM371_RS18660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM371_RS18665	COG1349	DNA-binding transcription factor activity
AM371_RS18670	COG0494	nUDIX hydrolase
AM371_RS18680	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM371_RS18685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM371_RS18685	COG1263	PTS System
AM371_RS18690	COG1609	Transcriptional regulator
AM371_RS18705	COG0583	DNA-binding transcription factor activity
AM371_RS18715	COG5339	Protein conserved in bacteria
AM371_RS18730	COG0114	fumarate hydratase activity
AM371_RS18735	COG2378	regulation of single-species biofilm formation
AM371_RS18750	COG1472	Belongs to the glycosyl hydrolase 3 family
AM371_RS18755	COG1649	PFAM Uncharacterised BCR, COG1649
AM371_RS18760	COG2814	Major facilitator Superfamily
AM371_RS18765	COG0583	DNA-binding transcription factor activity
AM371_RS18770	COG1940	carbohydrate kinase activity
AM371_RS18775	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM371_RS18785	COG0789	Transcriptional regulator
AM371_RS18815	COG0477	Major facilitator Superfamily
AM371_RS18830	COG1742	UPF0060 membrane protein
AM371_RS18835	COG4221	oxidoreductase activity
AM371_RS18845	COG4772	TonB-dependent receptor
AM371_RS18850	COG3712	iron ion homeostasis
AM371_RS18855	COG1595	DNA-templated transcription, initiation
AM371_RS18860	COG0402	S-adenosylhomocysteine deaminase activity
AM371_RS18910	COG0339	signal peptide processing
AM371_RS18915	COG2271	Major facilitator Superfamily
AM371_RS18920	COG1335	isochorismatase
AM371_RS18925	COG3473	Maleate cis-trans isomerase
AM371_RS18930	COG0596	Alpha beta hydrolase
AM371_RS18935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM371_RS18940	COG2309	aminopeptidase activity
AM371_RS18945	COG1846	Transcriptional regulator
AM371_RS18950	COG2080	2 iron, 2 sulfur cluster binding
AM371_RS18955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM371_RS18955	COG2010	Cytochrome c
AM371_RS18965	COG0583	DNA-binding transcription factor activity
AM371_RS19025	COG2140	Oxalate decarboxylase
AM371_RS19060	COG0596	Alpha beta hydrolase
AM371_RS19125	COG2814	Major facilitator Superfamily
AM371_RS19145	COG0768	penicillin binding
AM371_RS19160	COG0840	transmembrane signaling receptor activity
AM371_RS19190	COG1349	DNA-binding transcription factor activity
AM371_RS19195	COG0673	inositol 2-dehydrogenase activity
AM371_RS19200	COG2814	Major facilitator Superfamily
AM371_RS19220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM371_RS19225	COG2862	Uncharacterized protein family, UPF0114
AM371_RS19240	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM371_RS19250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM371_RS19250	COG3453	Protein conserved in bacteria
AM371_RS19255	COG1064	alcohol dehydrogenase
AM371_RS19265	COG3284	Transcriptional regulator
AM371_RS19275	COG2814	Major facilitator Superfamily
AM371_RS19280	COG3300	MHYT domain
AM371_RS19280	COG5001	Diguanylate cyclase
AM371_RS19300	COG1802	Transcriptional regulator
AM371_RS19310	COG2267	carboxylic ester hydrolase activity
AM371_RS19315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM371_RS19320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM371_RS19325	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS19330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM371_RS19370	COG0583	DNA-binding transcription factor activity
AM371_RS19375	COG0076	glutamate decarboxylase activity
AM371_RS19380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM371_RS19385	COG1902	pentaerythritol trinitrate reductase activity
AM371_RS19385	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM371_RS19395	COG0148	phosphopyruvate hydratase activity
AM371_RS19405	COG1227	inorganic diphosphatase activity
AM371_RS19410	COG5002	protein histidine kinase activity
AM371_RS19410	COG5001	Diguanylate cyclase
AM371_RS19410	COG3447	MASE1 domain protein
AM371_RS19435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM371_RS19445	COG0583	DNA-binding transcription factor activity
AM371_RS19470	COG4221	oxidoreductase activity
AM371_RS19475	COG4221	oxidoreductase activity
AM371_RS19490	COG1082	Xylose isomerase domain protein TIM barrel
AM371_RS19495	COG0673	inositol 2-dehydrogenase activity
AM371_RS19530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM371_RS19560	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM371_RS19565	COG1733	regulation of RNA biosynthetic process
AM371_RS19570	COG0477	Major facilitator Superfamily
AM371_RS19585	COG2382	esterase
AM371_RS19590	COG4774	siderophore transport
AM371_RS19600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM371_RS19605	COG0318	PFAM AMP-dependent synthetase and ligase
AM371_RS19610	COG0693	protein deglycase activity
AM371_RS19625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM371_RS19635	COG2890	protein-(glutamine-N5) methyltransferase activity
AM371_RS19640	COG2957	Belongs to the agmatine deiminase family
AM371_RS19645	COG0583	DNA-binding transcription factor activity
AM371_RS19670	COG0778	Nitroreductase
AM371_RS19675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM371_RS19675	COG2010	Cytochrome c
AM371_RS19680	COG2010	Cytochrome c
AM371_RS19680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM371_RS19685	COG2080	2 iron, 2 sulfur cluster binding
AM371_RS19690	COG1737	Transcriptional regulator
AM371_RS19695	COG2723	6-phospho-beta-galactosidase activity
AM371_RS19705	COG2814	Major facilitator Superfamily
AM371_RS19710	COG3048	D-serine ammonia-lyase activity
AM371_RS19725	COG5507	3-demethylubiquinone-9 3-methyltransferase
AM371_RS19730	COG2199	diguanylate cyclase activity
AM371_RS19755	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS19760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM371_RS19765	COG0697	spore germination
AM371_RS19770	COG2271	Major facilitator Superfamily
AM371_RS19785	COG1196	nuclear chromosome segregation
AM371_RS19785	COG3264	Mechanosensitive ion channel
AM371_RS19790	COG0488	(ABC) transporter
AM371_RS19800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM371_RS19805	COG0483	inositol monophosphate 1-phosphatase activity
AM371_RS19810	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM371_RS19820	COG2239	Acts as a magnesium transporter
AM371_RS19840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM371_RS19845	COG0697	spore germination
AM371_RS19940	COG0306	phosphate transporter
AM371_RS19960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM371_RS19980	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM371_RS19985	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AM371_RS20000	COG2222	sugar isomerase
AM371_RS20015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM371_RS20025	COG0589	response to stress
AM371_RS20030	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM371_RS20035	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM371_RS20045	COG0531	amino acid
AM371_RS20070	COG0745	RESPONSE REGULATOR receiver
AM371_RS20075	COG2205	protein histidine kinase activity
AM371_RS20080	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AM371_RS20085	COG2267	carboxylic ester hydrolase activity
AM371_RS20095	COG3591	Belongs to the peptidase S1B family
AM371_RS20100	COG1643	Atp-dependent helicase
AM371_RS20105	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM371_RS20110	COG3784	Protein of unknown function (DUF1318)
AM371_RS20120	COG2911	Protein conserved in bacteria
AM371_RS20135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM371_RS20140	COG3187	Heat shock protein
AM371_RS20145	COG3042	response to heat
AM371_RS20155	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM371_RS20155	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM371_RS20155	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM371_RS20155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM371_RS20160	COG0037	tRNA processing
AM371_RS20190	COG4166	transmembrane transport
AM371_RS20200	COG2866	Carboxypeptidase
AM371_RS20205	COG4948	Mandelate Racemase Muconate Lactonizing
AM371_RS20210	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM371_RS20220	COG3768	UPF0283 membrane protein
AM371_RS20225	COG3106	COG3106 Predicted ATPase
AM371_RS20235	COG1983	PspC domain protein
AM371_RS20245	COG1842	Phage shock protein A
AM371_RS20250	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM371_RS20265	COG1469	GTP cyclohydrolase I activity
AM371_RS20280	COG4171	peptide transport system, permease
AM371_RS20285	COG4172	Belongs to the ABC transporter superfamily
AM371_RS20290	COG4172	Belongs to the ABC transporter superfamily
AM371_RS20300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM371_RS20300	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM371_RS20320	COG0243	molybdopterin cofactor binding
AM371_RS20335	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AM371_RS20340	COG0477	Major facilitator Superfamily
AM371_RS20345	COG1473	amidohydrolase
AM371_RS20350	COG1966	Carbon starvation protein
AM371_RS20365	COG3210	domain, Protein
AM371_RS20410	COG3210	domain, Protein
AM371_RS20415	COG2831	hemolysin activation secretion protein
AM371_RS20420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM371_RS20425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM371_RS20430	COG1882	Formate acetyltransferase
AM371_RS20435	COG1349	DNA-binding transcription factor activity
AM371_RS20445	COG0023	Translation Initiation Factor
AM371_RS20465	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM371_RS20470	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM371_RS20475	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS20480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM371_RS20485	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS20490	COG1129	ABC transporter
AM371_RS20500	COG1879	ABC-type sugar transport system periplasmic component
AM371_RS20505	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS20510	COG3958	Transketolase
AM371_RS20515	COG3959	Transketolase, thiamine diphosphate binding domain
AM371_RS20520	COG1349	DNA-binding transcription factor activity
AM371_RS20525	COG0671	phosphoesterase, PA-phosphatase related
AM371_RS20535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM371_RS20540	COG0583	DNA-binding transcription factor activity
AM371_RS20555	COG0616	signal peptide processing
AM371_RS20560	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS20565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM371_RS20570	COG1187	pseudouridine synthase activity
AM371_RS20585	COG0009	L-threonylcarbamoyladenylate synthase
AM371_RS20590	COG0613	PHP domain protein
AM371_RS20605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM371_RS20615	COG0133	tryptophan synthase activity
AM371_RS20620	COG0159	tryptophan synthase activity
AM371_RS20635	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM371_RS20650	COG2917	probably involved in intracellular septation
AM371_RS20655	COG1607	acyl-coa hydrolase
AM371_RS20665	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM371_RS20670	COG2350	Protein conserved in bacteria
AM371_RS20680	COG0583	DNA-binding transcription factor activity
AM371_RS20690	COG1609	Transcriptional regulator
AM371_RS20710	COG1070	Carbohydrate kinase
AM371_RS20715	COG1129	ABC transporter
AM371_RS20720	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS20725	COG1879	ABC-type sugar transport system periplasmic component
AM371_RS20740	COG0783	Belongs to the Dps family
AM371_RS20750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM371_RS20755	COG3099	Belongs to the UPF0263 family
AM371_RS20765	COG0444	Belongs to the ABC transporter superfamily
AM371_RS20770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM371_RS20785	COG4166	transmembrane transport
AM371_RS20790	COG2095	MarC family integral membrane protein
AM371_RS20795	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS20795	COG1454	alcohol dehydrogenase
AM371_RS20820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM371_RS20825	COG0745	RESPONSE REGULATOR receiver
AM371_RS20830	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM371_RS20835	COG3012	SEC-C Motif Domain Protein
AM371_RS20840	COG0788	formyltetrahydrofolate deformylase activity
AM371_RS20870	COG0708	Exodeoxyribonuclease III
AM371_RS20875	COG0494	nUDIX hydrolase
AM371_RS20890	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AM371_RS20900	COG0778	Nitroreductase
AM371_RS20905	COG0616	signal peptide processing
AM371_RS20910	COG0252	asparaginase activity
AM371_RS20915	COG1335	isochorismatase
AM371_RS20925	COG3139	Protein of unknown function (DUF1315)
AM371_RS20930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM371_RS20950	COG3713	MltA-interacting MipA family protein
AM371_RS20955	COG2766	serine protein kinase
AM371_RS20960	COG2718	Belongs to the UPF0229 family
AM371_RS21005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM371_RS21010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM371_RS21020	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM371_RS21025	COG2719	SpoVR family
AM371_RS21030	COG2186	Transcriptional regulator
AM371_RS21035	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM371_RS21040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AM371_RS21045	COG2983	Belongs to the UPF0260 family
AM371_RS21050	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM371_RS21055	COG2951	lytic endotransglycosylase activity
AM371_RS21060	COG3100	YcgL domain-containing protein
AM371_RS21065	COG0850	regulation of cytokinetic process
AM371_RS21070	COG2894	cell division
AM371_RS21075	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AM371_RS21080	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM371_RS21085	COG0318	PFAM AMP-dependent synthetase and ligase
AM371_RS21090	COG3065	identical protein binding
AM371_RS21100	COG1199	ATP-dependent helicase activity
AM371_RS21105	COG0251	oxidation-reduction process
AM371_RS21110	COG2076	Multidrug Resistance protein
AM371_RS21115	COG2076	Multidrug Resistance protein
AM371_RS21120	COG0800	Aldolase
AM371_RS21125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM371_RS21130	COG1737	Transcriptional regulator
AM371_RS21135	COG0469	pyruvate kinase activity
AM371_RS21145	COG1560	Kdo2-lipid A biosynthetic process
AM371_RS21150	COG0739	heme binding
AM371_RS21155	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM371_RS21160	COG1121	(ABC) transporter
AM371_RS21165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM371_RS21170	COG2255	four-way junction helicase activity
AM371_RS21175	COG0632	four-way junction helicase activity
AM371_RS21180	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM371_RS21185	COG0217	transcriptional regulatory protein
AM371_RS21190	COG0494	nUDIX hydrolase
AM371_RS21195	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM371_RS21205	COG1335	isochorismatase
AM371_RS21210	COG1801	Protein of unknown function DUF72
AM371_RS21215	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM371_RS21220	COG2226	methyltransferase
AM371_RS21225	COG0500	methyltransferase
AM371_RS21230	COG0545	Peptidyl-prolyl cis-trans isomerase
AM371_RS21240	COG3142	Participates in the control of copper homeostasis
AM371_RS21245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM371_RS21250	COG3102	Protein conserved in bacteria
AM371_RS21255	COG0018	arginyl-trna synthetase
AM371_RS21265	COG0673	inositol 2-dehydrogenase activity
AM371_RS21270	COG3132	Protein of unknown function, DUF480
AM371_RS21275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM371_RS21280	COG0477	Major facilitator Superfamily
AM371_RS21290	COG2999	glutathione oxidoreductase activity
AM371_RS21310	COG3097	Belongs to the UPF0267 family
AM371_RS21315	COG3141	response to X-ray
AM371_RS21320	COG0513	Belongs to the DEAD box helicase family
AM371_RS21330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AM371_RS21335	COG3140	Belongs to the UPF0181 family
AM371_RS21340	COG1216	Glycosyl transferase, family 2
AM371_RS21350	COG0494	nUDIX hydrolase
AM371_RS21355	COG1760	l-serine dehydratase
AM371_RS21360	COG2200	EAL domain
AM371_RS21365	COG1253	flavin adenine dinucleotide binding
AM371_RS21370	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS21370	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM371_RS21375	COG3715	PTS system
AM371_RS21380	COG3716	PTS system mannose fructose sorbose family IID component
AM371_RS21385	COG4811	Protein of unknown function (DUF986)
AM371_RS21390	COG1971	Probably functions as a manganese efflux pump
AM371_RS21395	COG2226	methyltransferase
AM371_RS21400	COG1496	oxidoreductase activity
AM371_RS21425	COG1113	amino acid transport
AM371_RS21470	COG2207	Transcriptional regulator
AM371_RS21485	COG1652	LysM domain
AM371_RS21510	COG2988	succinylglutamate desuccinylase activity
AM371_RS21515	COG3724	N-succinylarginine dihydrolase activity
AM371_RS21520	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS21525	COG3138	arginine N-succinyltransferase
AM371_RS21530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM371_RS21540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM371_RS21545	COG1271	oxidase subunit
AM371_RS21550	COG1294	oxidase, subunit
AM371_RS21600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM371_RS21605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM371_RS21610	COG2181	nitrate reductase activity
AM371_RS21615	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM371_RS21620	COG1140	nitrate reductase beta subunit
AM371_RS21625	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM371_RS21675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM371_RS21680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM371_RS21685	COG3710	Transcriptional regulator
AM371_RS21690	COG2223	nitrite transmembrane transporter activity
AM371_RS21695	COG3850	Histidine kinase
AM371_RS21700	COG2197	response regulator
AM371_RS21705	COG4932	domain protein
AM371_RS21720	COG4608	Belongs to the ABC transporter superfamily
AM371_RS21725	COG0444	Belongs to the ABC transporter superfamily
AM371_RS21730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM371_RS21735	COG0601	transmembrane transport
AM371_RS21745	COG0583	DNA-binding transcription factor activity
AM371_RS21750	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM371_RS21755	COG4572	Cation transport regulator
AM371_RS21760	COG2375	cellular response to nickel ion
AM371_RS21765	COG0387	Pfam Sodium calcium exchanger
AM371_RS21775	COG1702	phosphate starvation-inducible protein PhoH
AM371_RS21785	COG2822	iron ion transport
AM371_RS21790	COG0672	)-iron permease
AM371_RS21800	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM371_RS21800	COG0506	proline dehydrogenase activity
AM371_RS21800	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM371_RS21805	COG1126	abc transporter atp-binding protein
AM371_RS21810	COG0765	amino acid transport
AM371_RS21815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM371_RS21820	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AM371_RS21830	COG1191	sigma factor activity
AM371_RS21875	COG0583	DNA-binding transcription factor activity
AM371_RS21890	COG1677	Flagellar hook-basal body complex protein FliE
AM371_RS21900	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM371_RS21905	COG1317	bacterial-type flagellum organization
AM371_RS21910	COG1157	protein secretion by the type III secretion system
AM371_RS21915	COG2882	bacterial-type flagellum organization
AM371_RS21975	COG1256	bacterial-type flagellum assembly
AM371_RS22015	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AM371_RS22020	COG1558	bacterial-type flagellum-dependent cell motility
AM371_RS22025	COG1815	bacterial-type flagellum-dependent cell motility
AM371_RS22035	COG2747	anti-sigma28 factor FlgM
AM371_RS22040	COG3418	PFAM FlgN family protein
AM371_RS22060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM371_RS22065	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM371_RS22070	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AM371_RS22075	COG0745	RESPONSE REGULATOR receiver
AM371_RS22085	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AM371_RS22090	COG0840	transmembrane signaling receptor activity
AM371_RS22095	COG0840	transmembrane signaling receptor activity
AM371_RS22100	COG0835	chemotaxis
AM371_RS22105	COG2198	Histidine kinase
AM371_RS22105	COG0643	Histidine kinase
AM371_RS22140	COG0589	response to stress
AM371_RS22145	COG2130	NADP-dependent
AM371_RS22150	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AM371_RS22325	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM371_RS22330	COG3483	tryptophan 2,3-dioxygenase activity
AM371_RS22335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM371_RS22345	COG3059	membrane
AM371_RS22350	COG2207	Transcriptional regulator
AM371_RS22355	COG1609	Transcriptional regulator
AM371_RS22380	COG1335	isochorismatase
AM371_RS22385	COG4977	sequence-specific DNA binding
AM371_RS22390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM371_RS22400	COG3712	iron ion homeostasis
AM371_RS22405	COG1595	DNA-templated transcription, initiation
AM371_RS22410	COG1629	transport
AM371_RS22415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM371_RS22490	COG3781	membrane
AM371_RS22495	COG2837	iron assimilation
AM371_RS22505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM371_RS22515	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AM371_RS22540	COG1285	pathogenesis
AM371_RS22550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM371_RS22560	COG0076	glutamate decarboxylase activity
AM371_RS22595	COG3321	synthase
AM371_RS22595	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS22595	COG0604	alcohol dehydrogenase
AM371_RS22605	COG0583	DNA-binding transcription factor activity
AM371_RS22610	COG3753	Protein conserved in bacteria
AM371_RS22615	COG2261	transglycosylase associated protein
AM371_RS22625	COG1560	Kdo2-lipid A biosynthetic process
AM371_RS22630	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM371_RS22640	COG5001	Diguanylate cyclase
AM371_RS22640	COG4251	negative regulation of phosphorylation
AM371_RS22640	COG3706	GGDEF domain
AM371_RS22640	COG2203	Gaf domain
AM371_RS22650	COG2030	dehydratase
AM371_RS22650	COG1012	belongs to the aldehyde dehydrogenase family
AM371_RS22655	COG3396	Phenylacetate-CoA oxygenase
AM371_RS22660	COG3460	Phenylacetate-CoA oxygenase
AM371_RS22665	COG3396	Phenylacetate-CoA oxygenase
AM371_RS22670	COG2151	metal-sulfur cluster biosynthetic enzyme
AM371_RS22675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM371_RS22680	COG1024	Enoyl-CoA hydratase
AM371_RS22685	COG1024	Enoyl-CoA hydratase
AM371_RS22690	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM371_RS22695	COG2050	protein possibly involved in aromatic compounds catabolism
AM371_RS22700	COG0183	Belongs to the thiolase family
AM371_RS22705	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM371_RS22710	COG3327	negative regulation of DNA-templated transcription, initiation
AM371_RS22715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM371_RS22720	COG1113	amino acid transport
AM371_RS22740	COG0583	DNA-binding transcription factor activity
AM371_RS22745	COG0625	glutathione transferase activity
AM371_RS22780	COG0667	Aldo Keto reductase
AM371_RS22790	COG4772	TonB-dependent receptor
AM371_RS22795	COG4993	Dehydrogenase
AM371_RS22830	COG3539	Fimbrial protein
AM371_RS22840	COG3121	Chaperone
AM371_RS22845	COG3188	usher protein
AM371_RS22850	COG3539	Fimbrial protein
AM371_RS22865	COG0534	Mate efflux family protein
AM371_RS22895	COG1414	Transcriptional regulator
AM371_RS22900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM371_RS22905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM371_RS22910	COG0183	Belongs to the thiolase family
AM371_RS22920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM371_RS22925	COG0583	DNA-binding transcription factor activity
AM371_RS22930	COG3485	protocatechuate 3,4-dioxygenase
AM371_RS22935	COG3485	protocatechuate 3,4-dioxygenase
AM371_RS22960	COG3228	Belongs to the MtfA family
AM371_RS22970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM371_RS22975	COG4977	sequence-specific DNA binding
AM371_RS22985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM371_RS22990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM371_RS22995	COG1116	anion transmembrane transporter activity
AM371_RS23000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM371_RS23005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM371_RS23020	COG0656	L-ascorbic acid biosynthetic process
AM371_RS23035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM371_RS23050	COG3238	Protein conserved in bacteria
AM371_RS23055	COG1247	-acetyltransferase
AM371_RS23075	COG0583	DNA-binding transcription factor activity
AM371_RS23085	COG0859	PFAM glycosyl transferase family 9
AM371_RS23105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM371_RS23125	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS23130	COG1169	isochorismate synthase
AM371_RS23145	COG0471	metal ion transport
AM371_RS23150	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AM371_RS23160	COG3051	citrate lyase alpha subunit
AM371_RS23165	COG2301	Belongs to the HpcH HpaI aldolase family
AM371_RS23170	COG3052	prosthetic group binding
AM371_RS23175	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AM371_RS23180	COG4565	transcriptional regulatory protein
AM371_RS23185	COG3250	beta-galactosidase activity
AM371_RS23215	COG2197	response regulator
AM371_RS23245	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AM371_RS23265	COG2070	2-Nitropropane dioxygenase
AM371_RS23285	COG2271	Major facilitator Superfamily
AM371_RS23315	COG0411	ABC transporter
AM371_RS23365	COG0583	DNA-binding transcription factor activity
AM371_RS23375	COG0456	acetyltransferase
AM371_RS23390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM371_RS23395	COG0156	8-amino-7-oxononanoate synthase activity
AM371_RS23400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM371_RS23405	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM371_RS23410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM371_RS23415	COG2244	polysaccharide biosynthetic process
AM371_RS23425	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM371_RS23430	COG0795	lipopolysaccharide-transporting ATPase activity
AM371_RS23460	COG0583	DNA-binding transcription factor activity
AM371_RS23470	COG1609	Transcriptional regulator
AM371_RS23480	COG3623	hexulose-6-phosphate isomerase
AM371_RS23485	COG1070	Carbohydrate kinase
AM371_RS23490	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS23500	COG1879	ABC-type sugar transport system periplasmic component
AM371_RS23505	COG1063	alcohol dehydrogenase
AM371_RS23515	COG1473	amidohydrolase
AM371_RS23520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM371_RS23525	COG2926	Belongs to the UPF0265 family
AM371_RS23530	COG1289	transmembrane transporter activity
AM371_RS23535	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM371_RS23560	COG2925	Exonuclease
AM371_RS23565	COG0531	amino acid
AM371_RS23575	COG0174	glutamine synthetase
AM371_RS23580	COG1396	sequence-specific DNA binding
AM371_RS23580	COG1917	Cupin 2, conserved barrel domain protein
AM371_RS23585	COG1129	ABC transporter
AM371_RS23590	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM371_RS23595	COG4771	TonB-dependent receptor
AM371_RS23610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM371_RS23620	COG0833	amino acid
AM371_RS23625	COG0583	DNA-binding transcription factor activity
AM371_RS23635	COG2855	membrane
AM371_RS23640	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AM371_RS23645	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM371_RS23645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM371_RS23645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM371_RS23650	COG1105	Belongs to the carbohydrate kinase PfkB family
AM371_RS23655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS23655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS23665	COG0494	nUDIX hydrolase
AM371_RS23670	COG3005	denitrification pathway
AM371_RS23675	COG0243	molybdopterin cofactor binding
AM371_RS23695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM371_RS23700	COG1312	Catalyzes the dehydration of D-mannonate
AM371_RS23705	COG0246	Mannitol dehydrogenase
AM371_RS23715	COG0523	cobalamin synthesis protein
AM371_RS23720	COG0671	phosphoesterase, PA-phosphatase related
AM371_RS23730	COG0791	NLP P60 protein
AM371_RS23735	COG2200	EAL domain
AM371_RS23740	COG4166	transmembrane transport
AM371_RS23745	COG4174	ABC transporter (Permease)
AM371_RS23750	COG4239	(ABC) transporter, permease
AM371_RS23755	COG4172	Belongs to the ABC transporter superfamily
AM371_RS23765	COG2814	Major facilitator Superfamily
AM371_RS23770	COG1187	pseudouridine synthase activity
AM371_RS23775	COG1061	Type III restriction enzyme res subunit
AM371_RS23780	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AM371_RS23785	COG3081	Nucleoid-associated protein
AM371_RS23790	COG3082	Protein of unknown function (DUF1414)
AM371_RS23795	COG3083	sulfuric ester hydrolase activity
AM371_RS23805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM371_RS23810	COG0625	glutathione transferase activity
AM371_RS23825	COG2271	Major facilitator Superfamily
AM371_RS23875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM371_RS23890	COG0346	lactoylglutathione lyase activity
AM371_RS23905	COG2223	nitrite transmembrane transporter activity
AM371_RS23910	COG0642	Histidine kinase
AM371_RS23910	COG2198	Histidine kinase
AM371_RS23920	COG0784	Response regulator, receiver
AM371_RS23920	COG2205	protein histidine kinase activity
AM371_RS23930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM371_RS23935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM371_RS23945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM371_RS23965	COG0814	amino acid
AM371_RS23980	COG0318	PFAM AMP-dependent synthetase and ligase
AM371_RS23990	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM371_RS23995	COG0596	Alpha beta hydrolase
AM371_RS24000	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AM371_RS24005	COG4575	ribosome binding
AM371_RS24010	COG1063	alcohol dehydrogenase
AM371_RS24015	COG1028	Short-chain dehydrogenase reductase Sdr
AM371_RS24020	COG1609	Transcriptional regulator
AM371_RS24035	COG0583	DNA-binding transcription factor activity
AM371_RS24040	COG1007	ATP synthesis coupled electron transport
AM371_RS24045	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM371_RS24050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM371_RS24055	COG0713	ATP synthesis coupled electron transport
AM371_RS24060	COG0839	Belongs to the complex I subunit 6 family
AM371_RS24070	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM371_RS24075	COG1034	ATP synthesis coupled electron transport
AM371_RS24090	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM371_RS24090	COG0649	NAD binding
AM371_RS24095	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM371_RS24100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM371_RS24105	COG0583	DNA-binding transcription factor activity
AM371_RS24110	COG0436	Aminotransferase
AM371_RS24115	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM371_RS24120	COG0471	metal ion transport
AM371_RS24120	COG0490	domain, Protein
AM371_RS24125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM371_RS24130	COG3013	Belongs to the UPF0304 family
AM371_RS24135	COG3092	negative regulation of chromosome organization
AM371_RS24140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM371_RS24145	COG0857	belongs to the CobB CobQ family
AM371_RS24145	COG0280	phosphate acetyltransferase
AM371_RS24160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM371_RS24165	COG3959	Transketolase, thiamine diphosphate binding domain
AM371_RS24170	COG3037	sugar-specific permease SgaT UlaA
AM371_RS24180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM371_RS24185	COG1609	Transcriptional regulator
AM371_RS24190	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM371_RS24195	COG0622	Phosphoesterase
AM371_RS24200	COG0625	glutathione transferase activity
AM371_RS24205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM371_RS24210	COG1090	epimerase
AM371_RS24215	COG4598	ABC transporter
AM371_RS24225	COG4215	(ABC) transporter
AM371_RS24230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM371_RS24235	COG0163	prenyltransferase activity
AM371_RS24240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM371_RS24245	COG1286	toxin biosynthetic process
AM371_RS24250	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM371_RS24255	COG0285	dihydrofolate synthase activity
AM371_RS24260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM371_RS24265	COG0586	Pfam SNARE associated Golgi protein
AM371_RS24275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM371_RS24280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM371_RS24290	COG0697	spore germination
AM371_RS24295	COG0642	Histidine kinase
AM371_RS24335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM371_RS24340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM371_RS24380	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM371_RS24385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM371_RS24400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM371_RS24405	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM371_RS24405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM371_RS24415	COG3101	peptidyl-lysine hydroxylation
AM371_RS24420	COG0730	response to heat
AM371_RS24430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM371_RS24435	COG2890	protein-(glutamine-N5) methyltransferase activity
AM371_RS24440	COG2840	Smr protein MutS2
AM371_RS24445	COG2062	phosphohistidine phosphatase, SixA
AM371_RS24450	COG1024	Enoyl-CoA hydratase
AM371_RS24450	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM371_RS24455	COG0183	Belongs to the thiolase family
AM371_RS24460	COG3691	Protein conserved in bacteria
AM371_RS24475	COG4235	cytochrome complex assembly
AM371_RS24475	COG3088	subunit of a heme lyase
AM371_RS24480	COG4235	cytochrome complex assembly
AM371_RS24480	COG3088	subunit of a heme lyase
AM371_RS24485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM371_RS24490	COG1138	Cytochrome C-type biogenesis protein
AM371_RS24495	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AM371_RS24500	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM371_RS24505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM371_RS24510	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM371_RS24520	COG2116	formate transmembrane transporter activity
AM371_RS24530	COG2706	6-phosphogluconolactonase activity
AM371_RS24535	COG3708	Transcriptional regulator
AM371_RS24535	COG2207	Transcriptional regulator
AM371_RS24550	COG2197	response regulator
AM371_RS24560	COG0583	DNA-binding transcription factor activity
AM371_RS24570	COG0697	spore germination
AM371_RS24585	COG2951	lytic endotransglycosylase activity
AM371_RS24600	COG1215	transferase activity, transferring glycosyl groups