locus-tag	class	description
AN479_RS00040	COG3772	lysozyme
AN479_RS00060	COG1403	HNH endonuclease
AN479_RS00070	COG1846	Transcriptional regulator
AN479_RS00095	COG1475	DNA binding
AN479_RS00110	COG0582	viral genome integration into host DNA
AN479_RS00125	COG0538	isocitrate dehydrogenase activity
AN479_RS00130	COG1187	pseudouridine synthase activity
AN479_RS00145	COG0482	sulfurtransferase activity
AN479_RS00155	COG2915	High frequency lysogenization protein hflD homolog
AN479_RS00160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AN479_RS00165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN479_RS00180	COG2188	Transcriptional regulator
AN479_RS00185	COG1397	ADP-ribosylglycohydrolase
AN479_RS00190	COG0745	RESPONSE REGULATOR receiver
AN479_RS00200	COG2850	peptidyl-arginine hydroxylation
AN479_RS00205	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AN479_RS00210	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN479_RS00225	COG1177	transmembrane transport
AN479_RS00245	COG4591	ABC-type transport system involved in lipoprotein release permease component
AN479_RS00255	COG4591	ABC-type transport system involved in lipoprotein release permease component
AN479_RS00265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AN479_RS00270	COG3706	GGDEF domain
AN479_RS00275	COG4702	Belongs to the UPF0303 family
AN479_RS00280	COG0659	secondary active sulfate transmembrane transporter activity
AN479_RS00285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AN479_RS00290	COG2912	Transglutaminase-like superfamily
AN479_RS00295	COG3094	Invasion gene expression up-regulator, SirB
AN479_RS00300	COG2890	protein-(glutamine-N5) methyltransferase activity
AN479_RS00305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AN479_RS00310	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AN479_RS00315	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AN479_RS00320	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AN479_RS00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AN479_RS00335	COG0193	aminoacyl-tRNA hydrolase activity
AN479_RS00340	COG0659	secondary active sulfate transmembrane transporter activity
AN479_RS00345	COG0012	GTP binding
AN479_RS00370	COG3121	Chaperone
AN479_RS00375	COG3188	usher protein
AN479_RS00395	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AN479_RS00400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AN479_RS00410	COG0135	phosphoribosylanthranilate isomerase activity
AN479_RS00415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AN479_RS00420	COG1335	isochorismatase
AN479_RS00435	COG0740	serine-type endopeptidase activity
AN479_RS00445	COG0640	Transcriptional regulator
AN479_RS00450	COG0589	response to stress
AN479_RS00460	COG1464	Belongs to the NlpA lipoprotein family
AN479_RS00475	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN479_RS00480	COG1129	ABC transporter
AN479_RS00495	COG3290	protein histidine kinase activity
AN479_RS00500	COG4565	transcriptional regulatory protein
AN479_RS00520	COG3655	Transcriptional regulator
AN479_RS00530	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AN479_RS00570	COG1276	copper resistance
AN479_RS00575	COG2372	response to copper ion
AN479_RS00580	COG1528	Iron-storage protein
AN479_RS00600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN479_RS00605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN479_RS00610	COG1770	oligopeptidase
AN479_RS00615	COG2979	Protein of unknown function (DUF533)
AN479_RS00620	COG3381	protein complex oligomerization
AN479_RS00625	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AN479_RS00630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN479_RS00660	COG2207	Transcriptional regulator
AN479_RS00660	COG3708	Transcriptional regulator
AN479_RS00680	COG3134	Outer membrane lipoprotein
AN479_RS00685	COG1252	NADH dehydrogenase
AN479_RS00690	COG3150	esterase
AN479_RS00700	COG0510	thiamine kinase activity
AN479_RS00705	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AN479_RS00710	COG5633	Lipoprotein
AN479_RS00715	COG0537	adenosine 5'-monophosphoramidase activity
AN479_RS00720	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AN479_RS00725	COG1733	regulation of RNA biosynthetic process
AN479_RS00730	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS00745	COG1914	H( )-stimulated, divalent metal cation uptake system
AN479_RS00750	COG1321	iron dependent repressor
AN479_RS00775	COG1263	PTS System
AN479_RS00775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN479_RS00780	COG0084	hydrolase, TatD family'
AN479_RS00785	COG0470	DNA polymerase III
AN479_RS00790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AN479_RS00795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AN479_RS00800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN479_RS00805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN479_RS00810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN479_RS00825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN479_RS00830	COG0416	fatty acid biosynthetic process
AN479_RS00835	COG1399	metal-binding, possibly nucleic acid-binding protein
AN479_RS00845	COG0564	pseudouridine synthase activity
AN479_RS00850	COG1530	ribonuclease E activity
AN479_RS00855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN479_RS00860	COG0418	dihydroorotase activity
AN479_RS00900	COG0628	permease
AN479_RS00905	COG3038	cytochrome b561
AN479_RS00910	COG2353	YceI-like domain
AN479_RS00915	COG1054	Belongs to the UPF0176 family
AN479_RS00920	COG1560	Kdo2-lipid A biosynthetic process
AN479_RS00930	COG2814	Major facilitator Superfamily
AN479_RS00940	COG0346	lactoylglutathione lyase activity
AN479_RS00955	COG0640	Transcriptional regulator
AN479_RS00965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN479_RS00980	COG5645	(Lipo)protein
AN479_RS00985	COG2943	transferase activity, transferring hexosyl groups
AN479_RS00990	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AN479_RS01025	COG0322	excinuclease ABC activity
AN479_RS01030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN479_RS01040	COG1538	Outer membrane efflux protein
AN479_RS01050	COG0583	DNA-binding transcription factor activity
AN479_RS01080	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AN479_RS01110	COG0322	excinuclease ABC activity
AN479_RS01115	COG2197	response regulator
AN479_RS01125	COG3136	membrane protein required for alginate biosynthesis
AN479_RS01155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN479_RS01170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN479_RS01175	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS01180	COG0531	amino acid
AN479_RS01195	COG0589	response to stress
AN479_RS01200	COG2197	response regulator
AN479_RS01205	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN479_RS01210	COG0183	Belongs to the thiolase family
AN479_RS01215	COG0156	8-amino-7-oxononanoate synthase activity
AN479_RS01220	COG2814	Major facilitator Superfamily
AN479_RS01245	COG2271	Major facilitator Superfamily
AN479_RS01260	COG1113	amino acid transport
AN479_RS01290	COG0655	NAD(P)H dehydrogenase (quinone) activity
AN479_RS01320	COG3188	usher protein
AN479_RS01325	COG3121	Chaperone
AN479_RS01345	COG0670	Belongs to the BI1 family
AN479_RS01350	COG2920	part of a sulfur-relay system
AN479_RS01355	COG1254	Belongs to the acylphosphatase family
AN479_RS01360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AN479_RS01365	COG3785	DNA binding
AN479_RS01370	COG1832	CoA-binding protein
AN479_RS01380	COG1803	Methylglyoxal synthase
AN479_RS01385	COG0210	DNA helicase
AN479_RS01390	COG3304	Inner membrane component domain
AN479_RS01395	COG1289	transmembrane transporter activity
AN479_RS01400	COG3070	regulator of competence-specific genes
AN479_RS01420	COG1067	ATP-dependent peptidase activity
AN479_RS01425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AN479_RS01435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN479_RS01440	COG3009	Protein conserved in bacteria
AN479_RS01445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AN479_RS01445	COG3008	intermembrane lipid transfer
AN479_RS01450	COG2995	paraquat-inducible protein a
AN479_RS01455	COG0488	(ABC) transporter
AN479_RS01460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AN479_RS01460	COG0116	Belongs to the methyltransferase superfamily
AN479_RS01465	COG3217	Mosc domain protein beta barrel domain protein
AN479_RS01465	COG0633	Ferredoxin
AN479_RS01475	COG0167	dihydroorotate dehydrogenase activity
AN479_RS01480	COG0431	NADPH-dependent FMN reductase
AN479_RS01485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN479_RS01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN479_RS01495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN479_RS01505	COG0308	aminopeptidase N
AN479_RS01510	COG3706	GGDEF domain
AN479_RS01515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AN479_RS01520	COG0017	Asparaginyl-tRNA synthetase
AN479_RS01530	COG1448	Aminotransferase
AN479_RS01535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN479_RS01540	COG3108	Peptidase M15
AN479_RS01545	COG2989	Protein conserved in bacteria
AN479_RS01550	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AN479_RS01560	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AN479_RS01565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AN479_RS01570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AN479_RS01575	COG3173	Aminoglycoside phosphotransferase
AN479_RS01580	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AN479_RS01585	COG2835	tetraacyldisaccharide 4'-kinase activity
AN479_RS01590	COG3214	Protein conserved in bacteria
AN479_RS01595	COG1278	Cold shock
AN479_RS01605	COG5383	Protein conserved in bacteria
AN479_RS01610	COG1663	tetraacyldisaccharide 4'-kinase activity
AN479_RS01620	COG2333	competence protein COMEC
AN479_RS01620	COG0658	competence protein
AN479_RS01630	COG0539	negative regulation of cytoplasmic translation
AN479_RS01635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AN479_RS01640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AN479_RS01645	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AN479_RS01650	COG0252	asparaginase activity
AN479_RS01655	COG1944	ATP diphosphatase activity
AN479_RS01660	COG2116	formate transmembrane transporter activity
AN479_RS01665	COG1882	Formate acetyltransferase
AN479_RS01670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AN479_RS01675	COG2814	Major facilitator Superfamily
AN479_RS01685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AN479_RS01690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AN479_RS01695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AN479_RS01700	COG1674	ftsk spoiiie
AN479_RS01700	COG3107	peptidoglycan biosynthetic process
AN479_RS01710	COG0492	ferredoxin-NADP+ reductase activity
AN479_RS01720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AN479_RS01725	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AN479_RS01730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AN479_RS01735	COG0542	response to heat
AN479_RS01740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AN479_RS01745	COG1278	Cold shock
AN479_RS01755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN479_RS01760	COG2990	Protein conserved in bacteria
AN479_RS01765	COG3593	DNA synthesis involved in DNA repair
AN479_RS01770	COG2431	L-lysine efflux transmembrane transporter activity
AN479_RS01775	COG1151	hydroxylamine reductase activity
AN479_RS01780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN479_RS01785	COG0028	Belongs to the TPP enzyme family
AN479_RS01790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AN479_RS01800	COG0702	epimerase
AN479_RS01805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN479_RS01810	COG3023	N-Acetylmuramoyl-L-alanine amidase
AN479_RS01820	COG0393	Putative heavy-metal-binding
AN479_RS01830	COG1126	abc transporter atp-binding protein
AN479_RS01835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN479_RS01840	COG4215	(ABC) transporter
AN479_RS01845	COG4160	amino acid transport
AN479_RS01850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN479_RS01860	COG2026	Addiction module toxin, RelE StbE family
AN479_RS01865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN479_RS01875	COG1177	transmembrane transport
AN479_RS01880	COG1176	ABC-type spermidine putrescine transport system, permease component I
AN479_RS01885	COG3842	ATPase activity
AN479_RS01890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AN479_RS01900	COG0189	ligase activity
AN479_RS01920	COG0569	domain protein
AN479_RS01920	COG2985	domain, Protein
AN479_RS01940	COG4574	serine-type endopeptidase inhibitor activity
AN479_RS01950	COG0671	phosphoesterase, PA-phosphatase related
AN479_RS01960	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AN479_RS01965	COG1349	DNA-binding transcription factor activity
AN479_RS01970	COG0814	amino acid
AN479_RS01975	COG1760	l-serine dehydratase
AN479_RS01980	COG2197	response regulator
AN479_RS01985	COG0545	Peptidyl-prolyl cis-trans isomerase
AN479_RS02005	COG3121	Chaperone
AN479_RS02010	COG3188	usher protein
AN479_RS02040	COG1686	Belongs to the peptidase S11 family
AN479_RS02050	COG0626	cystathionine gamma-synthase activity
AN479_RS02065	COG0625	glutathione transferase activity
AN479_RS02070	COG2133	pyrroloquinoline quinone binding
AN479_RS02080	COG0598	Magnesium transport protein CorA
AN479_RS02085	COG3153	acetyltransferase
AN479_RS02085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN479_RS02090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AN479_RS02095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN479_RS02110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN479_RS02115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AN479_RS02125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AN479_RS02130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AN479_RS02130	COG0131	Imidazoleglycerol-phosphate dehydratase
AN479_RS02140	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AN479_RS02145	COG0107	imidazoleglycerol-phosphate synthase activity
AN479_RS02150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AN479_RS02150	COG0140	phosphoribosyl-ATP diphosphatase activity
AN479_RS02155	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AN479_RS02175	COG0438	transferase activity, transferring glycosyl groups
AN479_RS02180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AN479_RS02205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN479_RS02245	COG0297	glycogen (starch) synthase activity
AN479_RS02280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN479_RS02285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN479_RS02290	COG1253	flavin adenine dinucleotide binding
AN479_RS02295	COG3069	C4-dicarboxylate transmembrane transporter activity
AN479_RS02300	COG2982	Protein involved in outer membrane biogenesis
AN479_RS02305	COG0717	Belongs to the dCTP deaminase family
AN479_RS02310	COG0572	uridine kinase
AN479_RS02320	COG0489	protein tyrosine kinase activity
AN479_RS02325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN479_RS02325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN479_RS02335	COG2814	Major facilitator Superfamily
AN479_RS02340	COG1380	Effector of murein hydrolase LrgA
AN479_RS02345	COG1346	cytolysis
AN479_RS02350	COG0295	cytidine deaminase activity
AN479_RS02355	COG0281	malic enzyme
AN479_RS02360	COG2949	membrane
AN479_RS02380	COG1609	Transcriptional regulator
AN479_RS02385	COG2311	Membrane
AN479_RS02390	COG0302	gtp cyclohydrolase
AN479_RS02395	COG0477	Major facilitator Superfamily
AN479_RS02400	COG0583	DNA-binding transcription factor activity
AN479_RS02415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN479_RS02420	COG0601	transmembrane transport
AN479_RS02425	COG0747	negative chemotaxis
AN479_RS02430	COG4172	Belongs to the ABC transporter superfamily
AN479_RS02445	COG0303	'Molybdopterin
AN479_RS02455	COG0488	(ABC) transporter
AN479_RS02485	COG0583	DNA-binding transcription factor activity
AN479_RS02495	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AN479_RS02500	COG3811	Belongs to the UPF0386 family
AN479_RS02515	COG0583	DNA-binding transcription factor activity
AN479_RS02520	COG1335	isochorismatase
AN479_RS02540	COG0625	glutathione transferase activity
AN479_RS02550	COG0579	oxidoreductase
AN479_RS02555	COG2207	Transcriptional regulator
AN479_RS02555	COG3708	Transcriptional regulator
AN479_RS02565	COG3188	usher protein
AN479_RS02570	COG3121	Chaperone
AN479_RS02580	COG2200	EAL domain
AN479_RS02590	COG0069	glutamate synthase activity
AN479_RS02595	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AN479_RS02600	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS02605	COG1309	transcriptional regulator
AN479_RS02610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN479_RS02625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AN479_RS02630	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AN479_RS02635	COG0745	RESPONSE REGULATOR receiver
AN479_RS02640	COG5002	protein histidine kinase activity
AN479_RS02660	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AN479_RS02665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AN479_RS02670	COG1349	DNA-binding transcription factor activity
AN479_RS02675	COG2084	Dehydrogenase
AN479_RS02680	COG3395	kinase activity
AN479_RS02685	COG0235	Class ii aldolase
AN479_RS02690	COG3622	Belongs to the hyi family
AN479_RS02695	COG2610	gluconate transmembrane transporter activity
AN479_RS02710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN479_RS02715	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AN479_RS02725	COG2731	YhcH YjgK YiaL family protein
AN479_RS02730	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AN479_RS02740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN479_RS02745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN479_RS02750	COG0765	amino acid transport
AN479_RS02755	COG1126	abc transporter atp-binding protein
AN479_RS02760	COG0668	transmembrane transport
AN479_RS02770	COG1214	PFAM Peptidase M22, glycoprotease
AN479_RS02770	COG0456	acetyltransferase
AN479_RS02775	COG1309	transcriptional regulator
AN479_RS02785	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AN479_RS02790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN479_RS02815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AN479_RS02825	COG0477	Major facilitator Superfamily
AN479_RS02835	COG1280	lysine exporter protein (LysE YggA)
AN479_RS02840	COG2079	MmgE PrpD family protein
AN479_RS02860	COG0697	spore germination
AN479_RS02865	COG1522	sequence-specific DNA binding
AN479_RS02875	COG1942	4-Oxalocrotonate Tautomerase
AN479_RS02885	COG0625	glutathione transferase activity
AN479_RS02900	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AN479_RS02930	COG0697	spore germination
AN479_RS02935	COG0583	DNA-binding transcription factor activity
AN479_RS02960	COG1174	glycine betaine transport
AN479_RS02965	COG1125	glycine betaine transport
AN479_RS02970	COG1174	glycine betaine transport
AN479_RS02975	COG1732	Glycine betaine
AN479_RS02990	COG0583	DNA-binding transcription factor activity
AN479_RS02995	COG1335	isochorismatase
AN479_RS03005	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AN479_RS03015	COG0625	glutathione transferase activity
AN479_RS03020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN479_RS03035	COG0494	nUDIX hydrolase
AN479_RS03040	COG2897	thiosulfate sulfurtransferase activity
AN479_RS03045	COG0583	DNA-binding transcription factor activity
AN479_RS03080	COG0411	ABC transporter
AN479_RS03100	COG1802	Transcriptional regulator
AN479_RS03120	COG4807	Protein conserved in bacteria
AN479_RS03135	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AN479_RS03150	COG2084	Dehydrogenase
AN479_RS03170	COG0519	Catalyzes the synthesis of GMP from XMP
AN479_RS03175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AN479_RS03180	COG2011	ABC-type metal ion transport system permease component
AN479_RS03185	COG1464	Belongs to the NlpA lipoprotein family
AN479_RS03190	COG1309	transcriptional regulator
AN479_RS03205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AN479_RS03260	COG0697	spore germination
AN479_RS03265	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN479_RS03270	COG1070	Carbohydrate kinase
AN479_RS03280	COG0583	DNA-binding transcription factor activity
AN479_RS03295	COG1192	Involved in chromosome partitioning
AN479_RS03320	COG1846	Transcriptional regulator
AN479_RS03360	COG1472	Belongs to the glycosyl hydrolase 3 family
AN479_RS03370	COG0436	Aminotransferase
AN479_RS03380	COG1181	Belongs to the D-alanine--D-alanine ligase family
AN479_RS03395	COG0277	FAD linked oxidase domain protein
AN479_RS03400	COG0840	transmembrane signaling receptor activity
AN479_RS03410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN479_RS03420	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AN479_RS03440	COG0456	acetyltransferase
AN479_RS03450	COG1464	Belongs to the NlpA lipoprotein family
AN479_RS03460	COG2354	Protein conserved in bacteria
AN479_RS03480	COG1686	Belongs to the peptidase S11 family
AN479_RS03485	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AN479_RS03500	COG0586	Pfam SNARE associated Golgi protein
AN479_RS03505	COG0583	DNA-binding transcription factor activity
AN479_RS03525	COG0583	DNA-binding transcription factor activity
AN479_RS03560	COG2271	Major facilitator Superfamily
AN479_RS03565	COG1840	ABC-type Fe3 transport system, periplasmic component
AN479_RS03575	COG3842	ATPase activity
AN479_RS03585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN479_RS03590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AN479_RS03595	COG0513	Belongs to the DEAD box helicase family
AN479_RS03600	COG1309	transcriptional regulator
AN479_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN479_RS03610	COG1131	(ABC) transporter
AN479_RS03615	COG0842	Transport permease protein
AN479_RS03620	COG0842	Transport permease protein
AN479_RS03625	COG0670	Belongs to the BI1 family
AN479_RS03630	COG0314	molybdopterin synthase activity
AN479_RS03635	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AN479_RS03640	COG0315	cyclic pyranopterin monophosphate synthase activity
AN479_RS03645	COG0521	Mo-molybdopterin cofactor biosynthetic process
AN479_RS03650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AN479_RS03655	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AN479_RS03660	COG4628	conserved protein (DUF2132)
AN479_RS03665	COG0556	nucleotide-excision repair
AN479_RS03720	COG1881	PFAM PEBP family protein
AN479_RS03725	COG2706	6-phosphogluconolactonase activity
AN479_RS03730	COG0561	phosphatase activity
AN479_RS03740	COG4149	molybdate abc transporter
AN479_RS03745	COG0725	ABC transporter, periplasmic molybdate-binding protein
AN479_RS03750	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AN479_RS03755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN479_RS03760	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AN479_RS03770	COG4774	siderophore transport
AN479_RS03775	COG2005	Transcriptional regulator
AN479_RS03775	COG3585	molybdate ion transport
AN479_RS03780	COG1119	ATPase activity
AN479_RS03800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AN479_RS03805	COG2017	converts alpha-aldose to the beta-anomer
AN479_RS03815	COG0588	phosphoglycerate mutase activity
AN479_RS03830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN479_RS03835	COG2197	response regulator
AN479_RS03840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN479_RS03840	COG2205	protein histidine kinase activity
AN479_RS03845	COG1230	cation diffusion facilitator family transporter
AN479_RS03855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AN479_RS03905	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AN479_RS03910	COG2885	chlorophyll binding
AN479_RS03915	COG0823	Involved in the tonB-independent uptake of proteins
AN479_RS03920	COG3064	Membrane
AN479_RS03925	COG0848	biopolymer transport protein
AN479_RS03930	COG0811	peptide transport
AN479_RS03935	COG0824	Thioesterase
AN479_RS03940	COG3790	cyd operon protein YbgE
AN479_RS03945	COG4890	Cyd operon protein YbgT
AN479_RS03950	COG1294	oxidase, subunit
AN479_RS03955	COG1271	oxidase subunit
AN479_RS03960	COG0737	Belongs to the 5'-nucleotidase family
AN479_RS03965	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AN479_RS03970	COG0045	succinate-CoA ligase (ADP-forming) activity
AN479_RS03975	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN479_RS03980	COG0567	Dehydrogenase, E1 component
AN479_RS03985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AN479_RS03990	COG1053	succinate dehydrogenase
AN479_RS03995	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AN479_RS04030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AN479_RS04035	COG1984	allophanate hydrolase subunit 2
AN479_RS04040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AN479_RS04045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AN479_RS04050	COG5212	phosphodiesterase
AN479_RS04055	COG0415	Belongs to the DNA photolyase family
AN479_RS04060	COG3272	Protein of unknown function (DUF1722)
AN479_RS04075	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AN479_RS04080	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AN479_RS04085	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AN479_RS04090	COG2205	protein histidine kinase activity
AN479_RS04095	COG0745	RESPONSE REGULATOR receiver
AN479_RS04105	COG1695	Transcriptional regulator
AN479_RS04110	COG0033	Phosphoglucomutase
AN479_RS04115	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AN479_RS04120	COG0596	Alpha beta hydrolase
AN479_RS04140	COG0735	belongs to the Fur family
AN479_RS04160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN479_RS04165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN479_RS04165	COG1263	PTS System
AN479_RS04165	COG2190	(PTS) system
AN479_RS04170	COG0363	glucosamine-6-phosphate deaminase activity
AN479_RS04175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AN479_RS04180	COG1846	Transcriptional regulator
AN479_RS04180	COG1940	carbohydrate kinase activity
AN479_RS04185	COG0647	UMP catabolic process
AN479_RS04190	COG3469	chitinase activity
AN479_RS04195	COG0367	asparagine synthase
AN479_RS04230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN479_RS04235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AN479_RS04240	COG2824	Alkylphosphonate utilization operon protein PhnA
AN479_RS04245	COG1702	phosphate starvation-inducible protein PhoH
AN479_RS04250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AN479_RS04255	COG4535	Mg2 and Co2 transporter CorC
AN479_RS04260	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AN479_RS04270	COG0765	amino acid transport
AN479_RS04275	COG0765	amino acid transport
AN479_RS04280	COG1126	abc transporter atp-binding protein
AN479_RS04285	COG1957	nucleoside hydrolase
AN479_RS04295	COG2888	peptidyl-tyrosine sulfation
AN479_RS04300	COG0495	leucyl-tRNA aminoacylation
AN479_RS04305	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AN479_RS04310	COG1466	dna polymerase III delta subunit
AN479_RS04315	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AN479_RS04320	COG0799	negative regulation of ribosome biogenesis
AN479_RS04325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AN479_RS04330	COG0768	penicillin binding
AN479_RS04335	COG0772	Belongs to the SEDS family
AN479_RS04340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AN479_RS04345	COG1686	Belongs to the peptidase S11 family
AN479_RS04355	COG0321	lipoyl(octanoyl) transferase activity
AN479_RS04360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AN479_RS04370	COG3706	GGDEF domain
AN479_RS04380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AN479_RS04385	COG1309	transcriptional regulator
AN479_RS04390	COG2814	Major facilitator Superfamily
AN479_RS04400	COG1473	amidohydrolase
AN479_RS04405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN479_RS04410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN479_RS04420	COG0765	amino acid transport
AN479_RS04425	COG1126	abc transporter atp-binding protein
AN479_RS04435	COG1278	Cold shock
AN479_RS04440	COG2199	diguanylate cyclase activity
AN479_RS04470	COG1953	Uracil, thiamine, allantoin
AN479_RS04480	COG0859	PFAM glycosyl transferase family 9
AN479_RS04500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AN479_RS04505	COG2501	S4 domain
AN479_RS04510	COG0215	cysteine-tRNA ligase activity
AN479_RS04515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AN479_RS04520	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN479_RS04525	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AN479_RS04530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AN479_RS04535	COG2814	Major facilitator Superfamily
AN479_RS04540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AN479_RS04545	COG4181	ATPase activity
AN479_RS04550	COG2755	lipolytic protein G-D-S-L family
AN479_RS04555	COG0300	oxidoreductase activity
AN479_RS04560	COG3118	belongs to the thioredoxin family
AN479_RS04565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AN479_RS04570	COG0330	HflC and HflK could
AN479_RS04575	COG1585	Membrane protein implicated in regulation of membrane protease activity
AN479_RS04585	COG2217	Heavy metal translocating P-type atpase
AN479_RS04590	COG3735	TraB family
AN479_RS04595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AN479_RS04600	COG2027	D-alanyl-D-alanine carboxypeptidase
AN479_RS04620	COG3483	tryptophan 2,3-dioxygenase activity
AN479_RS04630	COG2814	Major facilitator Superfamily
AN479_RS04640	COG0737	Belongs to the 5'-nucleotidase family
AN479_RS04645	COG2223	nitrite transmembrane transporter activity
AN479_RS04650	COG4651	solute:proton antiporter activity
AN479_RS04650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN479_RS04655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN479_RS04660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AN479_RS04665	COG1929	Belongs to the glycerate kinase type-1 family
AN479_RS04670	COG2610	gluconate transmembrane transporter activity
AN479_RS04675	COG3835	regulator
AN479_RS04680	COG0563	adenylate kinase activity
AN479_RS04685	COG0326	Molecular chaperone. Has ATPase activity
AN479_RS04690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AN479_RS04700	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AN479_RS04705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN479_RS04710	COG2832	Protein of unknown function (DUF454)
AN479_RS04725	COG1196	nuclear chromosome segregation
AN479_RS04725	COG3264	Mechanosensitive ion channel
AN479_RS04730	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AN479_RS04735	COG1309	transcriptional regulator
AN479_RS04740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN479_RS04745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN479_RS04750	COG0254	rRNA binding
AN479_RS04755	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AN479_RS04760	COG0803	Belongs to the bacterial solute-binding protein 9 family
AN479_RS04765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN479_RS04770	COG1121	(ABC) transporter
AN479_RS04795	COG3397	chitin binding
AN479_RS04850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN479_RS04860	COG3031	protein transport across the cell outer membrane
AN479_RS04885	COG3695	enzyme binding
AN479_RS04890	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AN479_RS04895	COG1946	Acyl-CoA thioesterase
AN479_RS04900	COG0004	ammonium transporteR
AN479_RS04905	COG0347	Belongs to the P(II) protein family
AN479_RS04910	COG1132	(ABC) transporter
AN479_RS04915	COG1132	(ABC) transporter
AN479_RS04920	COG1522	sequence-specific DNA binding
AN479_RS04930	COG0561	phosphatase activity
AN479_RS04935	COG4533	DNA binding
AN479_RS04940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AN479_RS04945	COG0824	Thioesterase
AN479_RS04950	COG1555	photosystem II stabilization
AN479_RS04955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN479_RS04965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AN479_RS04970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AN479_RS04980	COG0544	peptidyl-prolyl cis-trans isomerase activity
AN479_RS04985	COG0271	Belongs to the BolA IbaG family
AN479_RS04990	COG3056	Lipoprotein
AN479_RS04995	COG2223	nitrite transmembrane transporter activity
AN479_RS05000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AN479_RS05005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AN479_RS05010	COG1845	cytochrome c oxidase, subunit III
AN479_RS05015	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AN479_RS05020	COG0109	protoheme IX farnesyltransferase activity
AN479_RS05025	COG2814	Major facilitator Superfamily
AN479_RS05030	COG1666	GTP binding
AN479_RS05035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AN479_RS05040	COG0693	protein deglycase activity
AN479_RS05045	COG0301	tRNA thio-modification
AN479_RS05045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN479_RS05050	COG1722	exodeoxyribonuclease VII activity
AN479_RS05055	COG0142	geranyltranstransferase activity
AN479_RS05060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AN479_RS05065	COG0667	Aldo Keto reductase
AN479_RS05070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AN479_RS05075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AN479_RS05080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN479_RS05085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AN479_RS05090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN479_RS05090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN479_RS05095	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AN479_RS05100	COG4238	major outer membrane lipoprotein
AN479_RS05105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN479_RS05115	COG1862	Preprotein translocase
AN479_RS05120	COG0343	queuine tRNA-ribosyltransferase activity
AN479_RS05125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AN479_RS05130	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AN479_RS05135	COG0450	alkyl hydroperoxide reductase
AN479_RS05145	COG0366	Alpha amylase catalytic
AN479_RS05150	COG0668	transmembrane transport
AN479_RS05175	COG5002	protein histidine kinase activity
AN479_RS05180	COG0745	RESPONSE REGULATOR receiver
AN479_RS05185	COG0420	3'-5' exonuclease activity
AN479_RS05190	COG0419	ATPase involved in DNA repair
AN479_RS05210	COG1940	carbohydrate kinase activity
AN479_RS05215	COG2974	May be involved in recombination
AN479_RS05220	COG3123	guanosine phosphorylase activity
AN479_RS05255	COG1595	DNA-templated transcription, initiation
AN479_RS05275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AN479_RS05325	COG2226	methyltransferase
AN479_RS05335	COG3416	Protein conserved in bacteria
AN479_RS05340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN479_RS05350	COG3011	Protein conserved in bacteria
AN479_RS05360	COG1335	isochorismatase
AN479_RS05380	COG1349	DNA-binding transcription factor activity
AN479_RS05410	COG3961	Belongs to the TPP enzyme family
AN479_RS05430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN479_RS05430	COG2169	Transcriptional regulator
AN479_RS05440	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS05445	COG2207	Transcriptional regulator
AN479_RS05455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN479_RS05470	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN479_RS05475	COG1733	regulation of RNA biosynthetic process
AN479_RS05480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN479_RS05485	COG0747	negative chemotaxis
AN479_RS05490	COG3038	cytochrome b561
AN479_RS05520	COG2314	TM2 domain
AN479_RS05525	COG2819	hydrolase of the alpha beta superfamily
AN479_RS05550	COG1073	alpha beta
AN479_RS05555	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AN479_RS05560	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN479_RS05565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN479_RS05570	COG0584	glycerophosphoryl diester phosphodiesterase
AN479_RS05575	COG2991	Protein conserved in bacteria
AN479_RS05580	COG1477	protein flavinylation
AN479_RS05585	COG2871	sodium ion transport
AN479_RS05590	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AN479_RS05595	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AN479_RS05600	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AN479_RS05605	COG1805	sodium ion transport
AN479_RS05610	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AN479_RS05615	COG3034	peptidoglycan biosynthetic process
AN479_RS05620	COG0121	glutamine amidotransferase
AN479_RS05625	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AN479_RS05630	COG1960	acyl-CoA dehydrogenase activity
AN479_RS05640	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AN479_RS05645	COG4413	Urea transporter
AN479_RS05650	COG0829	nickel cation binding
AN479_RS05655	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AN479_RS05660	COG0830	nickel cation binding
AN479_RS05665	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AN479_RS05670	COG0804	urea catabolic process
AN479_RS05675	COG0832	Belongs to the urease beta subunit family
AN479_RS05680	COG0831	urea catabolic process
AN479_RS05685	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AN479_RS05690	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AN479_RS05695	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AN479_RS05700	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AN479_RS05705	COG0235	Class ii aldolase
AN479_RS05710	COG0436	Aminotransferase
AN479_RS05725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AN479_RS05735	COG0765	amino acid transport
AN479_RS05790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN479_RS05795	COG0328	RNA-DNA hybrid ribonuclease activity
AN479_RS05800	COG2226	methyltransferase
AN479_RS05810	COG0741	lytic transglycosylase activity
AN479_RS05810	COG1388	LysM domain
AN479_RS05820	COG2814	Major facilitator Superfamily
AN479_RS05825	COG0583	DNA-binding transcription factor activity
AN479_RS05830	COG0656	L-ascorbic acid biosynthetic process
AN479_RS05860	COG0542	response to heat
AN479_RS05870	COG0564	pseudouridine synthase activity
AN479_RS05875	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN479_RS05880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AN479_RS05885	COG1605	Chorismate mutase
AN479_RS05885	COG0077	Prephenate dehydratase
AN479_RS05890	COG0287	Prephenate dehydrogenase
AN479_RS05890	COG1605	Chorismate mutase
AN479_RS05895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN479_RS05900	COG3137	Salt-induced outer membrane protein
AN479_RS05970	COG5301	cellulose 1,4-beta-cellobiosidase activity
AN479_RS06020	COG0335	large ribosomal subunit rRNA binding
AN479_RS06025	COG0336	Belongs to the RNA methyltransferase TrmD family
AN479_RS06030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AN479_RS06035	COG0228	four-way junction DNA binding
AN479_RS06040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AN479_RS06045	COG4137	Cytochrome C assembly protein
AN479_RS06050	COG4536	flavin adenine dinucleotide binding
AN479_RS06060	COG2918	glutathione biosynthetic process
AN479_RS06065	COG1238	metal cluster binding
AN479_RS06070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN479_RS06100	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AN479_RS06105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AN479_RS06110	COG2137	regulation of response to DNA damage stimulus
AN479_RS06135	COG1917	Cupin 2, conserved barrel domain protein
AN479_RS06135	COG2169	Transcriptional regulator
AN479_RS06140	COG2723	6-phospho-beta-galactosidase activity
AN479_RS06145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN479_RS06150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN479_RS06165	COG0667	Aldo Keto reductase
AN479_RS06185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AN479_RS06190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AN479_RS06195	COG4942	peptidase
AN479_RS06195	COG1388	LysM domain
AN479_RS06200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AN479_RS06205	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AN479_RS06210	COG0585	pseudouridine synthase activity
AN479_RS06215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AN479_RS06220	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AN479_RS06225	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AN479_RS06235	COG0765	amino acid transport
AN479_RS06255	COG2895	sulfate adenylyltransferase (ATP) activity
AN479_RS06260	COG0175	sulfate reduction
AN479_RS06265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN479_RS06265	COG1648	precorrin-2 dehydrogenase activity
AN479_RS06270	COG2234	aminopeptidase activity
AN479_RS06275	COG0175	sulfate reduction
AN479_RS06280	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN479_RS06285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN479_RS06290	COG0720	synthase
AN479_RS06300	COG0602	queuosine metabolic process
AN479_RS06305	COG2271	Major facilitator Superfamily
AN479_RS06310	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AN479_RS06315	COG2986	histidine ammonia-lyase
AN479_RS06345	COG0504	CTP synthase activity
AN479_RS06355	COG3956	TIGRFAM MazG family protein
AN479_RS06360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN479_RS06365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN479_RS06375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN479_RS06380	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AN479_RS06385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AN479_RS06395	COG2860	membrane
AN479_RS06400	COG0316	Belongs to the HesB IscA family
AN479_RS06410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AN479_RS06415	COG3725	Membrane protein required for beta-lactamase induction
AN479_RS06420	COG3023	N-Acetylmuramoyl-L-alanine amidase
AN479_RS06430	COG4969	Belongs to the N-Me-Phe pilin family
AN479_RS06435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN479_RS06440	COG1459	type II secretion system
AN479_RS06445	COG0516	GMP reductase activity
AN479_RS06455	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AN479_RS06460	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AN479_RS06465	COG0494	nUDIX hydrolase
AN479_RS06470	COG0653	protein targeting
AN479_RS06490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AN479_RS06495	COG0849	cell division
AN479_RS06500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AN479_RS06510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AN479_RS06515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AN479_RS06520	COG0772	Belongs to the SEDS family
AN479_RS06530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN479_RS06535	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AN479_RS06540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AN479_RS06545	COG0768	penicillin binding
AN479_RS06550	COG3116	cell division
AN479_RS06555	COG0275	rRNA processing
AN479_RS06560	COG2001	Belongs to the MraZ family
AN479_RS06580	COG0028	Belongs to the TPP enzyme family
AN479_RS06585	COG1022	Amp-dependent synthetase and ligase
AN479_RS06590	COG0583	DNA-binding transcription factor activity
AN479_RS06595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN479_RS06600	COG0473	3-isopropylmalate dehydrogenase activity
AN479_RS06605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AN479_RS06610	COG0066	3-isopropylmalate dehydratase activity
AN479_RS06615	COG0471	metal ion transport
AN479_RS06620	COG2814	Major facilitator Superfamily
AN479_RS06630	COG4143	(ABC) transporter
AN479_RS06635	COG1178	ABC-type Fe3 transport system permease component
AN479_RS06645	COG0028	Belongs to the TPP enzyme family
AN479_RS06650	COG0440	acetolactate synthase activity
AN479_RS06655	COG0586	Pfam SNARE associated Golgi protein
AN479_RS06660	COG0417	DNA replication proofreading
AN479_RS06665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AN479_RS06670	COG0564	pseudouridine synthase activity
AN479_RS06680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AN479_RS06690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AN479_RS06695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AN479_RS06700	COG2967	ApaG domain
AN479_RS06705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AN479_RS06715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AN479_RS06725	COG2966	Psort location CytoplasmicMembrane, score
AN479_RS06745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AN479_RS06750	COG0505	Belongs to the CarA family
AN479_RS06755	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AN479_RS06775	COG0583	DNA-binding transcription factor activity
AN479_RS06780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AN479_RS06785	COG1047	Peptidyl-prolyl cis-trans
AN479_RS06790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AN479_RS06795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AN479_RS06800	COG0196	riboflavin kinase activity
AN479_RS06805	COG0268	Binds directly to 16S ribosomal RNA
AN479_RS06810	COG0583	DNA-binding transcription factor activity
AN479_RS06815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AN479_RS06820	COG0484	heat shock protein binding
AN479_RS06825	COG0443	Heat shock 70 kDa protein
AN479_RS06830	COG1584	GPR1 FUN34 yaaH family protein
AN479_RS06840	COG0521	Mo-molybdopterin cofactor biosynthetic process
AN479_RS06845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AN479_RS06850	COG1115	amino acid carrier protein
AN479_RS06855	COG3022	response to hydroperoxide
AN479_RS06880	COG0745	RESPONSE REGULATOR receiver
AN479_RS06885	COG3045	CreA protein
AN479_RS06890	COG2207	Transcriptional regulator
AN479_RS06890	COG3708	Transcriptional regulator
AN479_RS06895	COG0406	alpha-ribazole phosphatase activity
AN479_RS06900	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AN479_RS06905	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AN479_RS06910	COG0741	lytic transglycosylase activity
AN479_RS06920	COG2199	diguanylate cyclase activity
AN479_RS06925	COG2885	chlorophyll binding
AN479_RS06930	COG0488	(ABC) transporter
AN479_RS06945	COG0604	alcohol dehydrogenase
AN479_RS06965	COG0560	Phosphoserine phosphatase
AN479_RS06970	COG3726	membrane protein affecting hemolysin expression
AN479_RS06975	COG0813	purine-nucleoside phosphorylase activity
AN479_RS06980	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AN479_RS06985	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AN479_RS06990	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AN479_RS06995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN479_RS07000	COG0084	hydrolase, TatD family'
AN479_RS07005	COG4667	esterase of the alpha-beta hydrolase superfamily
AN479_RS07010	COG3237	CsbD-like
AN479_RS07015	COG2823	Periplasmic or secreted lipoprotein
AN479_RS07020	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AN479_RS07030	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AN479_RS07035	COG2813	Specifically methylates the guanine in position
AN479_RS07040	COG0667	Aldo Keto reductase
AN479_RS07070	COG3706	GGDEF domain
AN479_RS07075	COG1309	transcriptional regulator
AN479_RS07095	COG0738	Major facilitator superfamily
AN479_RS07100	COG3254	rhamnose metabolic process
AN479_RS07105	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS07110	COG3618	amidohydrolase
AN479_RS07115	COG4948	Mandelate Racemase Muconate Lactonizing
AN479_RS07120	COG0179	Fumarylacetoacetate (FAA) hydrolase
AN479_RS07125	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS07130	COG2186	Transcriptional regulator
AN479_RS07135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN479_RS07140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN479_RS07145	COG2368	4-hydroxyphenylacetate
AN479_RS07165	COG3971	2-oxopent-4-enoate hydratase activity
AN479_RS07180	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS07195	COG1846	Transcriptional regulator
AN479_RS07200	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS07220	COG1113	amino acid transport
AN479_RS07250	COG2267	carboxylic ester hydrolase activity
AN479_RS07260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN479_RS07270	COG1454	alcohol dehydrogenase
AN479_RS07305	COG0811	peptide transport
AN479_RS07330	COG1376	ErfK ybiS ycfS ynhG family protein
AN479_RS07335	COG3708	Transcriptional regulator
AN479_RS07335	COG2207	Transcriptional regulator
AN479_RS07345	COG2207	Transcriptional regulator
AN479_RS07355	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS07360	COG2610	gluconate transmembrane transporter activity
AN479_RS07365	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN479_RS07380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN479_RS07385	COG0583	DNA-binding transcription factor activity
AN479_RS07410	COG0174	glutamine synthetase
AN479_RS07420	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AN479_RS07430	COG1116	anion transmembrane transporter activity
AN479_RS07460	COG1966	Carbon starvation protein
AN479_RS07465	COG2879	small protein
AN479_RS07470	COG0523	cobalamin synthesis protein
AN479_RS07485	COG1609	Transcriptional regulator
AN479_RS07490	COG1263	PTS System
AN479_RS07490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN479_RS07495	COG2723	6-phospho-beta-galactosidase activity
AN479_RS07530	COG0795	lipopolysaccharide-transporting ATPase activity
AN479_RS07535	COG0795	lipopolysaccharide-transporting ATPase activity
AN479_RS07540	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AN479_RS07545	COG2927	DNA polymerase III (CHI subunit)
AN479_RS07555	COG0456	acetyltransferase
AN479_RS07560	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AN479_RS07575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AN479_RS07580	COG4166	transmembrane transport
AN479_RS07585	COG0540	Belongs to the ATCase OTCase family
AN479_RS07605	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AN479_RS07610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AN479_RS07620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN479_RS07620	COG1263	PTS System
AN479_RS07625	COG0366	Alpha amylase catalytic
AN479_RS07630	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN479_RS07635	COG0583	DNA-binding transcription factor activity
AN479_RS07645	COG0602	queuosine metabolic process
AN479_RS07670	COG0701	Predicted permease
AN479_RS07675	COG2188	Transcriptional regulator
AN479_RS07680	COG3624	Phosphonate C-P lyase system protein PhnG
AN479_RS07685	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AN479_RS07690	COG3626	phosphonate metabolism
AN479_RS07695	COG3627	carbon phosphorus lyase activity
AN479_RS07700	COG4107	phosphonate C-P lyase system protein PhnK
AN479_RS07705	COG4778	phosphonate C-P lyase system protein PhnL
AN479_RS07710	COG3454	Phosphonate metabolism
AN479_RS07715	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AN479_RS07725	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AN479_RS07730	COG0702	epimerase
AN479_RS07735	COG3787	Belongs to the UPF0306 family
AN479_RS07740	COG1982	Orn Lys Arg decarboxylase major
AN479_RS07745	COG0531	amino acid
AN479_RS07750	COG2827	Endonuclease containing a URI domain
AN479_RS07755	COG3153	acetyltransferase
AN479_RS07760	COG3154	lipid carrier protein
AN479_RS07765	COG0826	peptidase U32
AN479_RS07770	COG0826	peptidase U32
AN479_RS07775	COG1605	Chorismate mutase
AN479_RS07780	COG2819	hydrolase of the alpha beta superfamily
AN479_RS07800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN479_RS07805	COG0425	Belongs to the sulfur carrier protein TusA family
AN479_RS07810	COG2391	methyltransferase activity
AN479_RS07815	COG0513	Belongs to the DEAD box helicase family
AN479_RS07825	COG1185	polyribonucleotide nucleotidyltransferase activity
AN479_RS07830	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AN479_RS07835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AN479_RS07840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AN479_RS07845	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AN479_RS07850	COG0195	Participates in both transcription termination and antitermination
AN479_RS07855	COG0779	Required for maturation of 30S ribosomal subunits
AN479_RS07870	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AN479_RS07875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN479_RS07880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AN479_RS07890	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AN479_RS07895	COG1534	Rna-binding protein
AN479_RS07905	COG2027	D-alanyl-D-alanine carboxypeptidase
AN479_RS07910	COG0745	RESPONSE REGULATOR receiver
AN479_RS07915	COG0642	Histidine kinase
AN479_RS07920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AN479_RS07925	COG0697	spore germination
AN479_RS07930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AN479_RS07935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AN479_RS07940	COG0142	geranyltranstransferase activity
AN479_RS07950	COG3423	Transcriptional regulator
AN479_RS07955	COG0039	L-malate dehydrogenase activity
AN479_RS07960	COG1438	arginine binding
AN479_RS07975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AN479_RS07980	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AN479_RS07990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AN479_RS07995	COG2105	PFAM AIG2 family protein
AN479_RS08000	COG2911	Protein conserved in bacteria
AN479_RS08005	COG0729	surface antigen
AN479_RS08010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN479_RS08015	COG1253	flavin adenine dinucleotide binding
AN479_RS08025	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AN479_RS08035	COG0737	Belongs to the 5'-nucleotidase family
AN479_RS08040	COG0545	Peptidyl-prolyl cis-trans isomerase
AN479_RS08045	COG3061	Opacity-associated protein A
AN479_RS08055	COG0359	binds to the 23S rRNA
AN479_RS08060	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AN479_RS08065	COG0360	Binds together with S18 to 16S ribosomal RNA
AN479_RS08080	COG1073	alpha beta
AN479_RS08085	COG3650	response to hydrogen peroxide
AN479_RS08095	COG3766	membrane
AN479_RS08100	COG1960	acyl-CoA dehydrogenase activity
AN479_RS08105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN479_RS08110	COG0557	exoribonuclease II activity
AN479_RS08115	COG1959	2 iron, 2 sulfur cluster binding
AN479_RS08120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AN479_RS08125	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AN479_RS08130	COG0330	HflC and HflK could
AN479_RS08135	COG0330	HflC and HflK could
AN479_RS08140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AN479_RS08150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AN479_RS08155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AN479_RS08160	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN479_RS08165	COG0802	atpase or kinase
AN479_RS08170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AN479_RS08170	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AN479_RS08175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AN479_RS08195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AN479_RS08200	COG1162	GTPase activity
AN479_RS08205	COG0688	phosphatidylethanolamine metabolic process
AN479_RS08210	COG1511	domain protein
AN479_RS08210	COG3264	Mechanosensitive ion channel
AN479_RS08215	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AN479_RS08220	COG1053	succinate dehydrogenase
AN479_RS08225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AN479_RS08230	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AN479_RS08235	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AN479_RS08240	COG3040	lipid binding
AN479_RS08250	COG5510	response to toxic substance
AN479_RS08255	COG5510	response to toxic substance
AN479_RS08260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AN479_RS08265	COG1509	lysine 2,3-aminomutase activity
AN479_RS08275	COG0840	transmembrane signaling receptor activity
AN479_RS08285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AN479_RS08300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AN479_RS08310	COG4232	protein-disulfide reductase activity
AN479_RS08315	COG1309	transcriptional regulator
AN479_RS08350	COG3121	Chaperone
AN479_RS08355	COG3188	usher protein
AN479_RS08385	COG3647	Membrane
AN479_RS08395	COG1535	isochorismatase
AN479_RS08395	COG3433	isochorismatase activity
AN479_RS08400	COG1021	2,3-dihydroxybenzoate-AMP ligase
AN479_RS08405	COG1169	isochorismate synthase
AN479_RS08415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN479_RS08415	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AN479_RS08425	COG2382	esterase
AN479_RS08430	COG4771	TonB-dependent receptor
AN479_RS08435	COG3391	amine dehydrogenase activity
AN479_RS08440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN479_RS08445	COG4774	siderophore transport
AN479_RS08445	COG1629	transport
AN479_RS08450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN479_RS08455	COG2226	methyltransferase
AN479_RS08455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN479_RS08455	COG3433	isochorismatase activity
AN479_RS08460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN479_RS08460	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AN479_RS08465	COG1301	dicarboxylic acid transport
AN479_RS08470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN479_RS08475	COG3162	membrane
AN479_RS08480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN479_RS08510	COG0138	bifunctional purine biosynthesis protein purh
AN479_RS08515	COG0151	Belongs to the GarS family
AN479_RS08535	COG1515	deoxyribonuclease V activity
AN479_RS08540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AN479_RS08545	COG2816	NAD+ diphosphatase activity
AN479_RS08550	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AN479_RS08560	COG0352	thiamine-phosphate diphosphorylase activity
AN479_RS08565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AN479_RS08570	COG2104	thiamine diphosphate biosynthetic process
AN479_RS08575	COG2022	thiamine diphosphate biosynthetic process
AN479_RS08590	COG5002	protein histidine kinase activity
AN479_RS08590	COG3850	Histidine kinase
AN479_RS08605	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AN479_RS08610	COG0085	RNA polymerase activity
AN479_RS08620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AN479_RS08635	COG0250	Participates in transcription elongation, termination and antitermination
AN479_RS08645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AN479_RS08680	COG1072	(Pantothenic acid kinase))
AN479_RS08685	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AN479_RS08685	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AN479_RS08690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AN479_RS08720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN479_RS08725	COG1739	Uncharacterized protein family UPF0029
AN479_RS08730	COG0006	proline dipeptidase activity
AN479_RS08740	COG1024	Enoyl-CoA hydratase
AN479_RS08740	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN479_RS08745	COG0183	Belongs to the thiolase family
AN479_RS08775	COG0084	hydrolase, TatD family'
AN479_RS08780	COG0805	protein transport
AN479_RS08790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN479_RS08795	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AN479_RS08800	COG3165	ubiquinone biosynthetic process from chorismate
AN479_RS08805	COG2226	methyltransferase
AN479_RS08810	COG1322	Protein conserved in bacteria
AN479_RS08815	COG0586	Pfam SNARE associated Golgi protein
AN479_RS08830	COG0412	Dienelactone hydrolase
AN479_RS08835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AN479_RS08845	COG0697	spore germination
AN479_RS08860	COG0584	glycerophosphoryl diester phosphodiesterase
AN479_RS08865	COG3842	ATPase activity
AN479_RS08875	COG1175	transmembrane transport
AN479_RS08880	COG1653	transport
AN479_RS08885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN479_RS08900	COG4177	L-phenylalanine transmembrane transporter activity
AN479_RS08905	COG0559	Belongs to the binding-protein-dependent transport system permease family
AN479_RS08915	COG0456	acetyltransferase
AN479_RS08935	COG2177	Part of the ABC transporter FtsEX involved in
AN479_RS08940	COG2884	Cell division ATP-binding protein ftsE
AN479_RS08945	COG0552	protein localization to endoplasmic reticulum
AN479_RS08950	COG0742	ribosomal rna small subunit methyltransferase
AN479_RS08955	COG3776	membrane
AN479_RS08965	COG3714	YhhN family
AN479_RS08980	COG2217	Heavy metal translocating P-type atpase
AN479_RS08985	COG0425	Belongs to the sulfur carrier protein TusA family
AN479_RS08990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AN479_RS09005	COG0247	lactate metabolic process
AN479_RS09015	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AN479_RS09020	COG2271	Major facilitator Superfamily
AN479_RS09025	COG0584	glycerophosphoryl diester phosphodiesterase
AN479_RS09030	COG0561	phosphatase activity
AN479_RS09035	COG2267	carboxylic ester hydrolase activity
AN479_RS09040	COG1280	lysine exporter protein (LysE YggA)
AN479_RS09045	COG1280	lysine exporter protein (LysE YggA)
AN479_RS09050	COG0514	ATP-dependent DNA helicase (RecQ)
AN479_RS09055	COG2050	protein possibly involved in aromatic compounds catabolism
AN479_RS09075	COG0210	DNA helicase
AN479_RS09080	COG1011	Hydrolase
AN479_RS09090	COG3159	Protein conserved in bacteria
AN479_RS09095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AN479_RS09100	COG5567	small periplasmic lipoprotein
AN479_RS09105	COG1965	Belongs to the frataxin family
AN479_RS09110	COG3072	Adenylate cyclase
AN479_RS09115	COG0181	hydroxymethylbilane synthase activity
AN479_RS09125	COG2959	enzyme of heme biosynthesis
AN479_RS09130	COG3071	HemY protein
AN479_RS09165	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AN479_RS09175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AN479_RS09180	COG2244	polysaccharide biosynthetic process
AN479_RS09185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN479_RS09190	COG0456	acetyltransferase
AN479_RS09195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AN479_RS09200	COG1088	dTDP-glucose 4,6-dehydratase activity
AN479_RS09205	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AN479_RS09210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AN479_RS09220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN479_RS09225	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AN479_RS09230	COG3118	belongs to the thioredoxin family
AN479_RS09240	COG0248	Ppx GppA phosphatase
AN479_RS09250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN479_RS09255	COG0612	Peptidase, M16
AN479_RS09260	COG1301	dicarboxylic acid transport
AN479_RS09265	COG2199	diguanylate cyclase activity
AN479_RS09265	COG2200	EAL domain
AN479_RS09270	COG3118	belongs to the thioredoxin family
AN479_RS09270	COG0457	Tetratricopeptide repeat
AN479_RS09275	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AN479_RS09280	COG1215	transferase activity, transferring glycosyl groups
AN479_RS09285	COG1215	transferase activity, transferring glycosyl groups
AN479_RS09310	COG2194	sulfuric ester hydrolase activity
AN479_RS09315	COG4608	Belongs to the ABC transporter superfamily
AN479_RS09320	COG0444	Belongs to the ABC transporter superfamily
AN479_RS09325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN479_RS09330	COG0601	transmembrane transport
AN479_RS09335	COG0747	negative chemotaxis
AN479_RS09350	COG2271	Major facilitator Superfamily
AN479_RS09360	COG2197	response regulator
AN479_RS09365	COG2194	sulfuric ester hydrolase activity
AN479_RS09370	COG1764	response to oxidative stress
AN479_RS09375	COG1846	Transcriptional regulator
AN479_RS09405	COG2814	Major facilitator Superfamily
AN479_RS09410	COG1902	pentaerythritol trinitrate reductase activity
AN479_RS09460	COG2807	transmembrane transport
AN479_RS09465	COG0583	DNA-binding transcription factor activity
AN479_RS09480	COG0402	S-adenosylhomocysteine deaminase activity
AN479_RS09485	COG1335	isochorismatase
AN479_RS09495	COG3274	enterobacterial common antigen metabolic process
AN479_RS09515	COG3276	selenocysteine insertion sequence binding
AN479_RS09520	COG1921	L-seryl-tRNASec selenium transferase activity
AN479_RS09525	COG0625	glutathione transferase activity
AN479_RS09535	COG3058	Necessary for formate dehydrogenase activity
AN479_RS09540	COG2864	formate dehydrogenase
AN479_RS09545	COG0437	4 iron, 4 sulfur cluster binding
AN479_RS09550	COG3383	formate dehydrogenase (NAD+) activity
AN479_RS09550	COG0243	molybdopterin cofactor binding
AN479_RS09555	COG0243	molybdopterin cofactor binding
AN479_RS09555	COG3383	formate dehydrogenase (NAD+) activity
AN479_RS09560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AN479_RS09565	COG0840	transmembrane signaling receptor activity
AN479_RS09575	COG2258	MOSC domain
AN479_RS09590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN479_RS09600	COG3722	fumarate hydratase activity
AN479_RS09605	COG0246	Mannitol dehydrogenase
AN479_RS09610	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS09610	COG2213	PTS system mannitol-specific
AN479_RS09625	COG0751	glycine-tRNA ligase activity
AN479_RS09630	COG0752	glycyl-tRNA synthetase alpha subunit
AN479_RS09640	COG2771	luxR family
AN479_RS09650	COG2818	Glycosylase
AN479_RS09660	COG2885	chlorophyll binding
AN479_RS09665	COG1609	Transcriptional regulator
AN479_RS09675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN479_RS09680	COG2814	Major facilitator Superfamily
AN479_RS09685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AN479_RS09700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN479_RS09705	COG0626	cystathionine gamma-synthase activity
AN479_RS09715	COG3977	Valine--pyruvate aminotransferase
AN479_RS09720	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AN479_RS09730	COG2985	domain, Protein
AN479_RS09735	COG0071	Belongs to the small heat shock protein (HSP20) family
AN479_RS09740	COG0071	Belongs to the small heat shock protein (HSP20) family
AN479_RS09745	COG5645	(Lipo)protein
AN479_RS09750	COG0823	Involved in the tonB-independent uptake of proteins
AN479_RS09755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AN479_RS09765	COG0561	phosphatase activity
AN479_RS09770	COG0187	DNA topoisomerase II activity
AN479_RS09775	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AN479_RS09780	COG0592	DNA-directed DNA polymerase activity
AN479_RS09790	COG0594	ribonuclease P activity
AN479_RS09795	COG0706	membrane insertase activity
AN479_RS09800	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AN479_RS09820	COG2091	lysine biosynthetic process via aminoadipic acid
AN479_RS09825	COG0431	NADPH-dependent FMN reductase
AN479_RS09835	COG2252	PERMEase
AN479_RS09840	COG2816	NAD+ diphosphatase activity
AN479_RS09845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN479_RS09850	COG0765	amino acid transport
AN479_RS09855	COG0765	amino acid transport
AN479_RS09860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN479_RS09865	COG0704	Plays a role in the regulation of phosphate uptake
AN479_RS09875	COG0581	inorganic phosphate transmembrane transporter activity
AN479_RS09880	COG0573	inorganic phosphate transmembrane transporter activity
AN479_RS09885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AN479_RS09895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AN479_RS09900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AN479_RS09905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AN479_RS09910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AN479_RS09915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AN479_RS09920	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AN479_RS09925	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AN479_RS09940	COG3312	ion transport
AN479_RS09945	COG0357	Ribosomal RNA small subunit methyltransferase G
AN479_RS09950	COG0445	tRNA wobble uridine modification
AN479_RS09955	COG0716	FMN binding
AN479_RS09960	COG1522	sequence-specific DNA binding
AN479_RS09965	COG2502	aspartate--ammonia ligase
AN479_RS09970	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AN479_RS09975	COG0714	Associated with various cellular activities
AN479_RS09980	COG3158	transport of potassium into the cell
AN479_RS09985	COG1869	D-ribose catabolic process
AN479_RS09990	COG1129	ABC transporter
AN479_RS09995	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN479_RS10005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN479_RS10010	COG1609	Transcriptional regulator
AN479_RS10015	COG0477	Major facilitator Superfamily
AN479_RS10020	COG2186	Transcriptional regulator
AN479_RS10045	COG1763	Mo-molybdopterin cofactor biosynthetic process
AN479_RS10050	COG0746	molybdenum cofactor guanylyltransferase activity
AN479_RS10055	COG3084	Protein conserved in bacteria
AN479_RS10060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN479_RS10065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN479_RS10070	COG0204	Acyl-transferase
AN479_RS10075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN479_RS10075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN479_RS10080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AN479_RS10090	COG3078	GTPase activator activity
AN479_RS10095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN479_RS10105	COG3852	Histidine kinase
AN479_RS10110	COG0174	glutamine synthetase
AN479_RS10115	COG1217	gtp-binding protein TYPA
AN479_RS10120	COG1011	Hydrolase
AN479_RS10125	COG1295	ribonuclease BN
AN479_RS10130	COG1490	D-aminoacyl-tRNA deacylase activity
AN479_RS10135	COG0456	acetyltransferase
AN479_RS10140	COG2982	Protein involved in outer membrane biogenesis
AN479_RS10145	COG2233	PERMEase
AN479_RS10150	COG0786	glutamate:sodium symporter activity
AN479_RS10155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AN479_RS10160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN479_RS10165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN479_RS10170	COG1758	RNA polymerase activity
AN479_RS10175	COG0194	GDP metabolic process
AN479_RS10180	COG2860	membrane
AN479_RS10190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN479_RS10200	COG1561	YicC-like family, N-terminal region
AN479_RS10205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AN479_RS10210	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AN479_RS10215	COG1309	transcriptional regulator
AN479_RS10220	COG0756	dUTP diphosphatase activity
AN479_RS10225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AN479_RS10230	COG2003	Belongs to the UPF0758 family
AN479_RS10235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AN479_RS10255	COG1519	Transferase
AN479_RS10265	COG0438	transferase activity, transferring glycosyl groups
AN479_RS10270	COG0438	transferase activity, transferring glycosyl groups
AN479_RS10275	COG0859	PFAM glycosyl transferase family 9
AN479_RS10290	COG1442	glycosyl transferase family 8
AN479_RS10290	COG1216	Glycosyl transferase, family 2
AN479_RS10295	COG3307	-O-antigen
AN479_RS10300	COG0438	transferase activity, transferring glycosyl groups
AN479_RS10305	COG0859	PFAM glycosyl transferase family 9
AN479_RS10310	COG0859	PFAM glycosyl transferase family 9
AN479_RS10315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN479_RS10320	COG0156	8-amino-7-oxononanoate synthase activity
AN479_RS10325	COG1063	alcohol dehydrogenase
AN479_RS10330	COG2861	carbohydrate metabolic process
AN479_RS10335	COG4942	peptidase
AN479_RS10340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AN479_RS10345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN479_RS10350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN479_RS10365	COG1045	serine acetyltransferase
AN479_RS10380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AN479_RS10385	COG2205	protein histidine kinase activity
AN479_RS10390	COG0745	RESPONSE REGULATOR receiver
AN479_RS10395	COG3678	ATP-independent chaperone mediated protein folding
AN479_RS10400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN479_RS10405	COG0205	6-phosphofructokinase activity
AN479_RS10410	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AN479_RS10415	COG0149	triose-phosphate isomerase activity
AN479_RS10425	COG3152	Membrane
AN479_RS10440	COG2814	Major facilitator Superfamily
AN479_RS10445	COG1494	fructose-1,6-bisphosphatase
AN479_RS10460	COG3074	FtsZ-dependent cytokinesis
AN479_RS10465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AN479_RS10470	COG1575	Belongs to the MenA family. Type 1 subfamily
AN479_RS10475	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AN479_RS10480	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AN479_RS10485	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AN479_RS10490	COG1609	Transcriptional regulator
AN479_RS10495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AN479_RS10500	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AN479_RS10505	COG0626	cystathionine gamma-synthase activity
AN479_RS10510	COG0527	aspartate kinase activity
AN479_RS10510	COG0460	homoserine dehydrogenase
AN479_RS10515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AN479_RS10520	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AN479_RS10535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AN479_RS10540	COG0137	argininosuccinate synthase activity
AN479_RS10545	COG0165	Argininosuccinate lyase
AN479_RS10560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN479_RS10565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN479_RS10565	COG0678	peroxiredoxin activity
AN479_RS10575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN479_RS10590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN479_RS10595	COG4206	TonB-dependent receptor
AN479_RS10600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AN479_RS10640	COG0583	DNA-binding transcription factor activity
AN479_RS10645	COG3085	chromosome segregation
AN479_RS10655	COG2814	Major facilitator Superfamily
AN479_RS10665	COG3978	acetolactate synthase activity
AN479_RS10670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN479_RS10675	COG0129	dihydroxy-acid dehydratase activity
AN479_RS10680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AN479_RS10700	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AN479_RS10705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN479_RS10710	COG2200	EAL domain
AN479_RS10715	COG2982	Protein involved in outer membrane biogenesis
AN479_RS10720	COG2134	cdp-diacylglycerol pyrophosphatase
AN479_RS10725	COG0477	Major facilitator Superfamily
AN479_RS10730	COG1295	ribonuclease BN
AN479_RS10735	COG1024	Enoyl-CoA hydratase
AN479_RS10740	COG5001	Diguanylate cyclase
AN479_RS10745	COG3678	ATP-independent chaperone mediated protein folding
AN479_RS10750	COG5441	Belongs to the UPF0261 family
AN479_RS10775	COG2205	protein histidine kinase activity
AN479_RS10775	COG0784	Response regulator, receiver
AN479_RS10785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN479_RS10790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AN479_RS10805	COG0339	signal peptide processing
AN479_RS10810	COG0742	ribosomal rna small subunit methyltransferase
AN479_RS10825	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN479_RS10830	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN479_RS10835	COG1129	ABC transporter
AN479_RS10850	COG0589	response to stress
AN479_RS10855	COG0583	DNA-binding transcription factor activity
AN479_RS10870	COG0306	phosphate transporter
AN479_RS10875	COG2081	HI0933 family
AN479_RS10895	COG0346	lactoylglutathione lyase activity
AN479_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS10915	COG0583	DNA-binding transcription factor activity
AN479_RS10935	COG0697	spore germination
AN479_RS10945	COG2197	response regulator
AN479_RS10965	COG3121	Chaperone
AN479_RS10970	COG3188	usher protein
AN479_RS11000	COG4619	ABC transporter
AN479_RS11005	COG0390	transport system, permease component
AN479_RS11015	COG2814	Major facilitator Superfamily
AN479_RS11015	COG0477	Major facilitator Superfamily
AN479_RS11025	COG3718	enzyme involved in inositol metabolism
AN479_RS11035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN479_RS11040	COG3962	Belongs to the TPP enzyme family
AN479_RS11045	COG0673	inositol 2-dehydrogenase activity
AN479_RS11050	COG1082	Xylose isomerase domain protein TIM barrel
AN479_RS11055	COG1082	Xylose isomerase domain protein TIM barrel
AN479_RS11060	COG3191	aminopeptidase activity
AN479_RS11065	COG1247	-acetyltransferase
AN479_RS11070	COG1741	Belongs to the pirin family
AN479_RS11075	COG1609	Transcriptional regulator
AN479_RS11080	COG2610	gluconate transmembrane transporter activity
AN479_RS11085	COG3265	gluconokinase activity
AN479_RS11090	COG2095	MarC family integral membrane protein
AN479_RS11095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AN479_RS11110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AN479_RS11115	COG1523	belongs to the glycosyl hydrolase 13 family
AN479_RS11120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AN479_RS11125	COG0297	glycogen (starch) synthase activity
AN479_RS11130	COG0058	SHG alpha-glucan phosphorylase activity
AN479_RS11135	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AN479_RS11140	COG1349	DNA-binding transcription factor activity
AN479_RS11145	COG0705	Rhomboid family
AN479_RS11150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN479_RS11195	COG2909	trisaccharide binding
AN479_RS11200	COG0058	SHG alpha-glucan phosphorylase activity
AN479_RS11205	COG1640	4-alpha-glucanotransferase
AN479_RS11210	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AN479_RS11210	COG0316	Belongs to the HesB IscA family
AN479_RS11215	COG1040	competence protein
AN479_RS11240	COG1918	ferrous iron import across plasma membrane
AN479_RS11245	COG2183	response to ionizing radiation
AN479_RS11250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN479_RS11255	COG0484	heat shock protein binding
AN479_RS11290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AN479_RS11295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AN479_RS11300	COG1011	Hydrolase
AN479_RS11310	COG0494	nUDIX hydrolase
AN479_RS11315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AN479_RS11340	COG4796	Type ii and iii secretion system protein
AN479_RS11345	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AN479_RS11350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AN479_RS11370	COG0546	phosphoglycolate phosphatase activity
AN479_RS11375	COG0180	Tryptophanyl-tRNA synthetase
AN479_RS11380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN479_RS11380	COG1648	precorrin-2 dehydrogenase activity
AN479_RS11390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN479_RS11395	COG0402	S-adenosylhomocysteine deaminase activity
AN479_RS11400	COG0738	Major facilitator superfamily
AN479_RS11405	COG1609	Transcriptional regulator
AN479_RS11410	COG1486	melibiose metabolic process
AN479_RS11415	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN479_RS11420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AN479_RS11425	COG3275	phosphorelay sensor kinase activity
AN479_RS11435	COG0433	COG0433 Predicted ATPase
AN479_RS11450	COG1289	transmembrane transporter activity
AN479_RS11455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN479_RS11460	COG1765	OsmC-like protein
AN479_RS11465	COG3954	Phosphoribulokinase
AN479_RS11470	COG3089	Belongs to the UPF0270 family
AN479_RS11475	COG0429	hydrolase of the alpha beta-hydrolase fold
AN479_RS11490	COG4521	taurine ABC transporter
AN479_RS11500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN479_RS11505	COG2175	clavaminate synthase activity
AN479_RS11510	COG0488	(ABC) transporter
AN479_RS11515	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN479_RS11525	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AN479_RS11530	COG1047	Peptidyl-prolyl cis-trans
AN479_RS11540	COG0545	Peptidyl-prolyl cis-trans isomerase
AN479_RS11545	COG2964	Protein conserved in bacteria
AN479_RS11550	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AN479_RS11555	COG2923	Belongs to the DsrF TusC family
AN479_RS11560	COG2168	tRNA wobble position uridine thiolation
AN479_RS11570	COG0049	tRNA binding
AN479_RS11580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AN479_RS11590	COG0051	transcription antitermination factor activity, RNA binding
AN479_RS11595	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AN479_RS11600	COG0088	Forms part of the polypeptide exit tunnel
AN479_RS11605	COG0089	rRNA binding
AN479_RS11615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AN479_RS11625	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AN479_RS11630	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AN479_RS11665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AN479_RS11670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AN479_RS11675	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AN479_RS11685	COG0201	protein transport
AN479_RS11690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AN479_RS11695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AN479_RS11700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AN479_RS11705	COG0202	RNA polymerase activity
AN479_RS11710	COG0203	ribosomal protein L17
AN479_RS11720	COG0789	Transcriptional regulator
AN479_RS11725	COG3036	rescue of stalled ribosome
AN479_RS11730	COG1970	mechanosensitive ion channel activity
AN479_RS11735	COG0569	domain protein
AN479_RS11740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN479_RS11740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AN479_RS11745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AN479_RS11750	COG0242	peptide deformylase activity
AN479_RS11755	COG0758	DNA mediated transformation
AN479_RS11760	COG2922	Belongs to the Smg family
AN479_RS11765	COG0551	DNA topoisomerase type I activity
AN479_RS11770	COG0009	L-threonylcarbamoyladenylate synthase
AN479_RS11775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AN479_RS11780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AN479_RS11820	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AN479_RS11825	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AN479_RS11835	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AN479_RS11840	COG0800	Aldolase
AN479_RS11845	COG0129	dihydroxy-acid dehydratase activity
AN479_RS11850	COG2610	gluconate transmembrane transporter activity
AN479_RS11855	COG3265	gluconokinase activity
AN479_RS11860	COG1414	Transcriptional regulator
AN479_RS11865	COG1410	methionine synthase
AN479_RS11865	COG0646	methionine synthase
AN479_RS11870	COG2188	Transcriptional regulator
AN479_RS11880	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AN479_RS11885	COG0395	ABC-type sugar transport system, permease component
AN479_RS11895	COG3842	ATPase activity
AN479_RS11900	COG1283	sodium-dependent phosphate transmembrane transporter activity
AN479_RS11920	COG0527	aspartate kinase activity
AN479_RS11930	COG0166	Belongs to the GPI family
AN479_RS11940	COG3223	Belongs to the PsiE family
AN479_RS11945	COG3833	ABC-type maltose transport systems, permease component
AN479_RS11950	COG1175	transmembrane transport
AN479_RS11955	COG2182	Extracellular solute-binding protein
AN479_RS11960	COG0366	Alpha amylase catalytic
AN479_RS11970	COG4580	involved in the transport of maltose and maltodextrins
AN479_RS11985	COG1609	Transcriptional regulator
AN479_RS11990	COG0477	Major facilitator Superfamily
AN479_RS11995	COG3161	chorismate lyase activity
AN479_RS12000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AN479_RS12005	COG2937	Belongs to the GPAT DAPAT family
AN479_RS12010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AN479_RS12015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AN479_RS12020	COG0534	Mate efflux family protein
AN479_RS12025	COG3237	CsbD-like
AN479_RS12030	COG0735	belongs to the Fur family
AN479_RS12050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN479_RS12060	COG0604	alcohol dehydrogenase
AN479_RS12080	COG1522	sequence-specific DNA binding
AN479_RS12085	COG1448	Aminotransferase
AN479_RS12095	COG2315	Protein conserved in bacteria
AN479_RS12100	COG0110	maltose O-acetyltransferase activity
AN479_RS12110	COG3713	MltA-interacting MipA family protein
AN479_RS12115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AN479_RS12135	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS12150	COG0625	glutathione transferase activity
AN479_RS12160	COG2252	PERMEase
AN479_RS12165	COG0025	NhaP-type Na H and K H
AN479_RS12170	COG0583	DNA-binding transcription factor activity
AN479_RS12175	COG1380	Effector of murein hydrolase LrgA
AN479_RS12195	COG1560	Kdo2-lipid A biosynthetic process
AN479_RS12220	COG2264	protein methyltransferase activity
AN479_RS12225	COG4145	pantothenate transmembrane transporter activity
AN479_RS12230	COG3924	membrane
AN479_RS12235	COG0439	Biotin carboxylase
AN479_RS12240	COG0511	ligase activity, forming carbon-carbon bonds
AN479_RS12245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AN479_RS12250	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AN479_RS12255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AN479_RS12260	COG0604	alcohol dehydrogenase
AN479_RS12265	COG2200	EAL domain
AN479_RS12265	COG2199	diguanylate cyclase activity
AN479_RS12270	COG1077	Cell shape determining protein MreB Mrl
AN479_RS12275	COG1792	Involved in formation and maintenance of cell shape
AN479_RS12280	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AN479_RS12285	COG0424	maF-like protein
AN479_RS12290	COG1530	ribonuclease E activity
AN479_RS12295	COG3164	Protein of unknown function
AN479_RS12300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN479_RS12305	COG0312	modulator of DNA gyrase
AN479_RS12310	COG2134	cdp-diacylglycerol pyrophosphatase
AN479_RS12335	COG0583	DNA-binding transcription factor activity
AN479_RS12345	COG1566	PFAM secretion protein HlyD family protein
AN479_RS12350	COG1289	transmembrane transporter activity
AN479_RS12360	COG2732	(Barnase) inhibitor
AN479_RS12365	COG3028	Belongs to the UPF0307 family
AN479_RS12370	COG0312	modulator of DNA gyrase
AN479_RS12375	COG3783	Cytochrome b(562)
AN479_RS12380	COG2207	Transcriptional regulator
AN479_RS12390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AN479_RS12400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN479_RS12430	COG3964	amidohydrolase
AN479_RS12450	COG3711	transcriptional antiterminator
AN479_RS12450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS12455	COG5499	transcription regulator containing HTH domain
AN479_RS12460	COG4680	protein conserved in bacteria
AN479_RS12465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS12470	COG1660	Displays ATPase and GTPase activities
AN479_RS12485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AN479_RS12490	COG1137	ATPase activity
AN479_RS12495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AN479_RS12500	COG3117	lipopolysaccharide transmembrane transporter activity
AN479_RS12505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AN479_RS12510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AN479_RS12510	COG0517	IMP dehydrogenase activity
AN479_RS12515	COG0530	calcium, potassium:sodium antiporter activity
AN479_RS12520	COG1127	ABC transporter
AN479_RS12525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AN479_RS12530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AN479_RS12535	COG2854	intermembrane phospholipid transfer
AN479_RS12540	COG3113	response to antibiotic
AN479_RS12545	COG5007	Belongs to the BolA IbaG family
AN479_RS12550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN479_RS12555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN479_RS12560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN479_RS12565	COG3105	Protein conserved in bacteria
AN479_RS12570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AN479_RS12575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AN479_RS12580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AN479_RS12585	COG0625	glutathione transferase activity
AN479_RS12590	COG2969	positive regulation of protein catabolic process
AN479_RS12600	COG0493	'glutamate synthase
AN479_RS12605	COG0067	glutamate synthase
AN479_RS12605	COG0069	glutamate synthase activity
AN479_RS12605	COG0070	glutamate synthase
AN479_RS12610	COG1242	4 iron, 4 sulfur cluster binding
AN479_RS12615	COG2198	Histidine kinase
AN479_RS12615	COG5002	protein histidine kinase activity
AN479_RS12615	COG0784	Response regulator, receiver
AN479_RS12620	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AN479_RS12635	COG2823	Periplasmic or secreted lipoprotein
AN479_RS12640	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AN479_RS12645	COG0792	nuclease activity
AN479_RS12650	COG3107	peptidoglycan biosynthetic process
AN479_RS12655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AN479_RS12665	COG1741	Belongs to the pirin family
AN479_RS12670	COG0583	DNA-binding transcription factor activity
AN479_RS12675	COG0435	Glutathione S-transferase
AN479_RS12680	COG2259	Doxx family
AN479_RS12690	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AN479_RS12695	COG4575	ribosome binding
AN479_RS12705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN479_RS12710	COG0586	Pfam SNARE associated Golgi protein
AN479_RS12725	COG2271	Major facilitator Superfamily
AN479_RS12730	COG1904	glucuronate isomerase
AN479_RS12735	COG2721	sulfolactate sulfo-lyase activity
AN479_RS12740	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AN479_RS12745	COG0861	Integral membrane protein TerC family
AN479_RS12750	COG0519	Catalyzes the synthesis of GMP from XMP
AN479_RS12755	COG0673	inositol 2-dehydrogenase activity
AN479_RS12760	COG1451	nucleotide metabolic process
AN479_RS12765	COG3093	addiction module antidote protein HigA
AN479_RS12770	COG3549	Plasmid maintenance system killer
AN479_RS12775	COG2813	Specifically methylates the guanine in position
AN479_RS12780	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN479_RS12780	COG1902	pentaerythritol trinitrate reductase activity
AN479_RS12785	COG0488	(ABC) transporter
AN479_RS12795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN479_RS12800	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS12810	COG0625	glutathione transferase activity
AN479_RS12855	COG0358	DNA primase activity
AN479_RS12860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AN479_RS12865	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AN479_RS12870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AN479_RS12875	COG1968	undecaprenyl-diphosphatase activity
AN479_RS12880	COG0617	tRNA 3'-terminal CCA addition
AN479_RS12885	COG4991	sh3 domain protein
AN479_RS12890	COG3025	triphosphatase activity
AN479_RS12895	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AN479_RS12900	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AN479_RS12900	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AN479_RS12910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AN479_RS12920	COG3384	dioxygenase
AN479_RS12925	COG0754	glutathionylspermidine amidase activity
AN479_RS12930	COG5463	Belongs to the UPF0441 family
AN479_RS12940	COG2376	Dihydroxyacetone kinase
AN479_RS12945	COG1461	Dihydroxyacetone kinase
AN479_RS12950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN479_RS12950	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AN479_RS12950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS12960	COG1538	Outer membrane efflux protein
AN479_RS12965	COG0494	nUDIX hydrolase
AN479_RS12970	COG3151	Protein conserved in bacteria
AN479_RS12975	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AN479_RS12980	COG3150	esterase
AN479_RS12985	COG0187	DNA topoisomerase II activity
AN479_RS12990	COG0583	DNA-binding transcription factor activity
AN479_RS12995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN479_RS13000	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN479_RS13005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AN479_RS13010	COG0204	Acyl-transferase
AN479_RS13015	COG2132	Multicopper oxidase
AN479_RS13020	COG0583	DNA-binding transcription factor activity
AN479_RS13025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AN479_RS13030	COG2211	Major facilitator Superfamily
AN479_RS13035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN479_RS13060	COG0656	L-ascorbic acid biosynthetic process
AN479_RS13065	COG1979	alcohol dehydrogenase
AN479_RS13070	COG2207	Transcriptional regulator
AN479_RS13075	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS13075	COG3321	synthase
AN479_RS13075	COG0604	alcohol dehydrogenase
AN479_RS13080	COG0583	DNA-binding transcription factor activity
AN479_RS13085	COG0586	Pfam SNARE associated Golgi protein
AN479_RS13100	COG0848	biopolymer transport protein
AN479_RS13130	COG4772	TonB-dependent receptor
AN479_RS13145	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AN479_RS13145	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AN479_RS13170	COG0454	-acetyltransferase
AN479_RS13175	COG2819	hydrolase of the alpha beta superfamily
AN479_RS13190	COG2706	6-phosphogluconolactonase activity
AN479_RS13215	COG1982	Orn Lys Arg decarboxylase major
AN479_RS13220	COG0741	lytic transglycosylase activity
AN479_RS13225	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AN479_RS13235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AN479_RS13240	COG3171	Protein conserved in bacteria
AN479_RS13245	COG2066	Belongs to the glutaminase family
AN479_RS13260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN479_RS13270	COG1872	DUF167
AN479_RS13275	COG0762	integral membrane protein
AN479_RS13280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN479_RS13285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AN479_RS13290	COG2805	Type II/IV secretion system protein
AN479_RS13295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AN479_RS13300	COG1678	Uncharacterized ACR, COG1678
AN479_RS13305	COG0189	ligase activity
AN479_RS13310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AN479_RS13315	COG2356	endonuclease I
AN479_RS13320	COG3091	SprT-like family
AN479_RS13330	COG2207	Transcriptional regulator
AN479_RS13330	COG3708	Transcriptional regulator
AN479_RS13335	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AN479_RS13345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AN479_RS13345	COG2010	Cytochrome c
AN479_RS13355	COG2010	Cytochrome c
AN479_RS13355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AN479_RS13360	COG1113	amino acid transport
AN479_RS13365	COG2186	Transcriptional regulator
AN479_RS13370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AN479_RS13375	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN479_RS13380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN479_RS13390	COG3112	Uncharacterised protein family (UPF0231)
AN479_RS13395	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AN479_RS13400	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AN479_RS13410	COG2132	Multicopper oxidase
AN479_RS13420	COG0288	reversible hydration of carbon dioxide
AN479_RS13425	COG1131	(ABC) transporter
AN479_RS13430	COG0842	Transport permease protein
AN479_RS13435	COG0726	polysaccharide deacetylase
AN479_RS13440	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AN479_RS13445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AN479_RS13450	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AN479_RS13460	COG0642	Histidine kinase
AN479_RS13465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AN479_RS13470	COG0617	tRNA 3'-terminal CCA addition
AN479_RS13475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN479_RS13485	COG1489	DNA binding
AN479_RS13490	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AN479_RS13495	COG1643	Atp-dependent helicase
AN479_RS13500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN479_RS13505	COG4774	siderophore transport
AN479_RS13510	COG1120	ATPase activity
AN479_RS13515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN479_RS13520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN479_RS13530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AN479_RS13535	COG1166	arginine decarboxylase activity
AN479_RS13540	COG0010	Belongs to the arginase family
AN479_RS13550	COG2271	Major facilitator Superfamily
AN479_RS13555	COG2146	nitrite reductase [NAD(P)H] activity
AN479_RS13570	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS13575	COG1414	Transcriptional regulator
AN479_RS13600	COG2267	carboxylic ester hydrolase activity
AN479_RS13605	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS13610	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AN479_RS13625	COG0501	Belongs to the peptidase M48B family
AN479_RS13630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AN479_RS13635	COG1114	Component of the transport system for branched-chain amino acids
AN479_RS13645	COG1175	transmembrane transport
AN479_RS13650	COG3842	ATPase activity
AN479_RS13655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN479_RS13665	COG4638	Rieske (2fe-2S)
AN479_RS13670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN479_RS13675	COG0473	3-isopropylmalate dehydrogenase activity
AN479_RS13680	COG0583	DNA-binding transcription factor activity
AN479_RS13685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN479_RS13690	COG0126	phosphoglycerate kinase activity
AN479_RS13695	COG0191	fructose-bisphosphate aldolase activity
AN479_RS13710	COG2271	Major facilitator Superfamily
AN479_RS13715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AN479_RS13725	COG3122	Protein conserved in bacteria
AN479_RS13735	COG1279	arginine transmembrane transporter activity
AN479_RS13745	COG0583	DNA-binding transcription factor activity
AN479_RS13755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN479_RS13760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AN479_RS13770	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AN479_RS13775	COG3079	Belongs to the UPF0149 family
AN479_RS13780	COG0006	proline dipeptidase activity
AN479_RS13785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN479_RS13790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN479_RS13795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AN479_RS13800	COG0509	glycine decarboxylation via glycine cleavage system
AN479_RS13805	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AN479_RS13805	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AN479_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS13850	COG1349	DNA-binding transcription factor activity
AN479_RS13860	COG1129	ABC transporter
AN479_RS13865	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN479_RS13875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AN479_RS13880	COG1940	carbohydrate kinase activity
AN479_RS13885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN479_RS13895	COG1272	protein, Hemolysin III
AN479_RS13905	COG0354	folic acid binding
AN479_RS13910	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AN479_RS13920	COG0745	RESPONSE REGULATOR receiver
AN479_RS13925	COG2205	protein histidine kinase activity
AN479_RS13930	COG4452	Inner membrane protein CreD
AN479_RS13935	COG0716	FMN binding
AN479_RS13940	COG4974	Belongs to the 'phage' integrase family
AN479_RS13945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN479_RS13950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AN479_RS13955	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AN479_RS13960	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AN479_RS13990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN479_RS13995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN479_RS14010	COG3247	response to pH
AN479_RS14015	COG4942	peptidase
AN479_RS14020	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AN479_RS14025	COG5265	(ABC) transporter
AN479_RS14030	COG1309	transcriptional regulator
AN479_RS14035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN479_RS14050	COG2814	Major facilitator Superfamily
AN479_RS14060	COG1304	FMN binding
AN479_RS14065	COG1620	l-lactate permease
AN479_RS14070	COG0583	DNA-binding transcription factor activity
AN479_RS14095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN479_RS14100	COG0577	efflux transmembrane transporter activity
AN479_RS14100	COG1136	(ABC) transporter
AN479_RS14110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN479_RS14115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN479_RS14120	COG0582	viral genome integration into host DNA
AN479_RS14125	COG3539	Fimbrial protein
AN479_RS14150	COG2197	response regulator
AN479_RS14155	COG2197	response regulator
AN479_RS14160	COG0582	viral genome integration into host DNA
AN479_RS14165	COG4615	Cyclic peptide transporter
AN479_RS14170	COG2807	transmembrane transport
AN479_RS14175	COG1349	DNA-binding transcription factor activity
AN479_RS14185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN479_RS14190	COG3715	PTS system
AN479_RS14195	COG3716	PTS system mannose fructose sorbose family IID component
AN479_RS14205	COG4178	(ABC) transporter
AN479_RS14225	COG0583	DNA-binding transcription factor activity
AN479_RS14230	COG0583	DNA-binding transcription factor activity
AN479_RS14250	COG1609	Transcriptional regulator
AN479_RS14260	COG0318	PFAM AMP-dependent synthetase and ligase
AN479_RS14260	COG0204	Acyl-transferase
AN479_RS14265	COG0477	Major facilitator Superfamily
AN479_RS14270	COG0667	Aldo Keto reductase
AN479_RS14280	COG0861	Integral membrane protein TerC family
AN479_RS14285	COG3066	DNA modification
AN479_RS14290	COG0494	nUDIX hydrolase
AN479_RS14300	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AN479_RS14305	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AN479_RS14310	COG2165	general secretion pathway protein
AN479_RS14330	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AN479_RS14335	COG1025	Belongs to the peptidase M16 family
AN479_RS14340	COG1074	ATP-dependent DNA helicase activity
AN479_RS14345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AN479_RS14350	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AN479_RS14350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AN479_RS14355	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN479_RS14375	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AN479_RS14380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AN479_RS14385	COG2166	iron-sulfur cluster assembly
AN479_RS14390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN479_RS14400	COG0583	DNA-binding transcription factor activity
AN479_RS14405	COG2363	Small membrane protein
AN479_RS14410	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AN479_RS14415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN479_RS14420	COG1611	Belongs to the LOG family
AN479_RS14435	COG2814	Major facilitator Superfamily
AN479_RS14440	COG3098	single-species biofilm formation
AN479_RS14445	COG2373	Large extracellular alpha-helical protein
AN479_RS14450	COG4953	penicillin-binding protein 1C
AN479_RS14455	COG0564	pseudouridine synthase activity
AN479_RS14475	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AN479_RS14485	COG0052	Belongs to the universal ribosomal protein uS2 family
AN479_RS14495	COG0528	UMP kinase activity
AN479_RS14500	COG0233	cytoplasmic translational termination
AN479_RS14505	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AN479_RS14515	COG0575	Belongs to the CDS family
AN479_RS14520	COG0750	zinc metalloprotease
AN479_RS14525	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN479_RS14530	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AN479_RS14535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN479_RS14540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AN479_RS14545	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN479_RS14550	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN479_RS14555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AN479_RS14560	COG0587	DNA-directed DNA polymerase activity
AN479_RS14565	COG0825	malonyl-CoA metabolic process
AN479_RS14570	COG1982	Orn Lys Arg decarboxylase major
AN479_RS14575	COG0346	lactoylglutathione lyase activity
AN479_RS14580	COG3710	Transcriptional regulator
AN479_RS14585	COG0531	amino acid
AN479_RS14595	COG3104	oligopeptide transport
AN479_RS14600	COG0037	tRNA processing
AN479_RS14610	COG4568	rho-dependent transcription termination
AN479_RS14620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AN479_RS14625	COG3015	lipoprotein NlpE involved in copper resistance
AN479_RS14630	COG0442	prolyl-tRNA aminoacylation
AN479_RS14635	COG1720	tRNA m6t6A37 methyltransferase activity
AN479_RS14650	COG2011	ABC-type metal ion transport system permease component
AN479_RS14660	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AN479_RS14690	COG0477	Major facilitator Superfamily
AN479_RS14695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN479_RS14700	COG0045	succinate-CoA ligase (ADP-forming) activity
AN479_RS14700	COG1042	CoA-binding domain protein
AN479_RS14700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN479_RS14705	COG3148	PFAM DTW domain containing protein
AN479_RS14710	COG3118	belongs to the thioredoxin family
AN479_RS14715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN479_RS14720	COG2814	Major facilitator Superfamily
AN479_RS14725	COG1566	PFAM secretion protein HlyD family protein
AN479_RS14735	COG1846	Transcriptional regulator
AN479_RS14745	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AN479_RS14750	COG2814	Major facilitator Superfamily
AN479_RS14755	COG0583	DNA-binding transcription factor activity
AN479_RS14760	COG2113	Glycine betaine
AN479_RS14765	COG4176	ABC-type proline glycine betaine transport system permease component
AN479_RS14775	COG4565	transcriptional regulatory protein
AN479_RS14785	COG3493	citrate carrier protein
AN479_RS14790	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN479_RS14795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AN479_RS14800	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS14830	COG1780	Probably involved in ribonucleotide reductase function
AN479_RS14835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN479_RS14840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN479_RS14850	COG4575	ribosome binding
AN479_RS14865	COG0477	Major facilitator Superfamily
AN479_RS14875	COG0477	Major facilitator Superfamily
AN479_RS14895	COG2840	Smr protein MutS2
AN479_RS14900	COG2259	Doxx family
AN479_RS14905	COG3592	Divergent 4Fe-4S mono-cluster
AN479_RS14910	COG2388	GCN5-related N-acetyl-transferase
AN479_RS14935	COG0454	-acetyltransferase
AN479_RS14945	COG3182	Iron-regulated membrane protein
AN479_RS14950	COG0583	DNA-binding transcription factor activity
AN479_RS14965	COG1566	PFAM secretion protein HlyD family protein
AN479_RS14975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AN479_RS14980	COG2867	negative regulation of translational initiation
AN479_RS14985	COG2914	Belongs to the UPF0125 (RnfH) family
AN479_RS14990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN479_RS14995	COG0497	DNA recombination
AN479_RS15000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN479_RS15005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AN479_RS15010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AN479_RS15030	COG0513	Belongs to the DEAD box helicase family
AN479_RS15035	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AN479_RS15040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AN479_RS15055	COG3026	antisigma factor binding
AN479_RS15060	COG3086	response to oxidative stress
AN479_RS15070	COG0481	GTPase activity
AN479_RS15080	COG0571	ribonuclease III activity
AN479_RS15085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AN479_RS15090	COG1381	Involved in DNA repair and RecF pathway recombination
AN479_RS15095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AN479_RS15100	COG0736	holo-[acyl-carrier-protein] synthase activity
AN479_RS15105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AN479_RS15110	COG1737	Transcriptional regulator
AN479_RS15115	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AN479_RS15120	COG1263	PTS System
AN479_RS15120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN479_RS15125	COG0560	Phosphoserine phosphatase
AN479_RS15140	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AN479_RS15150	COG2205	protein histidine kinase activity
AN479_RS15155	COG3170	Tfp pilus assembly protein FimV
AN479_RS15160	COG2204	response regulator
AN479_RS15165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN479_RS15165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AN479_RS15170	COG0347	Belongs to the P(II) protein family
AN479_RS15175	COG0583	DNA-binding transcription factor activity
AN479_RS15185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AN479_RS15190	COG3842	ATPase activity
AN479_RS15195	COG1176	ABC-type spermidine putrescine transport system, permease component I
AN479_RS15200	COG1177	transmembrane transport
AN479_RS15205	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS15210	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AN479_RS15220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN479_RS15220	COG1017	nitric oxide dioxygenase activity
AN479_RS15225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AN479_RS15230	COG2814	Major facilitator Superfamily
AN479_RS15235	COG3711	transcriptional antiterminator
AN479_RS15240	COG3683	transport system, periplasmic component
AN479_RS15245	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AN479_RS15260	COG1959	2 iron, 2 sulfur cluster binding
AN479_RS15265	COG1104	cysteine desulfurase activity
AN479_RS15270	COG0822	iron-sulfur transferase activity
AN479_RS15275	COG0316	Belongs to the HesB IscA family
AN479_RS15280	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AN479_RS15285	COG0443	Heat shock 70 kDa protein
AN479_RS15290	COG0633	Ferredoxin
AN479_RS15295	COG2975	iron-sulfur cluster assembly
AN479_RS15300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AN479_RS15310	COG0105	UTP biosynthetic process
AN479_RS15315	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AN479_RS15325	COG1426	Protein conserved in bacteria
AN479_RS15330	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AN479_RS15335	COG0124	histidyl-tRNA synthetase
AN479_RS15340	COG2976	Protein conserved in bacteria
AN479_RS15345	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN479_RS15350	COG1160	GTP binding
AN479_RS15360	COG1645	bacterial-type flagellum-dependent swarming motility
AN479_RS15375	COG1609	Transcriptional regulator
AN479_RS15380	COG2271	Major facilitator Superfamily
AN479_RS15390	COG1570	exodeoxyribonuclease VII activity
AN479_RS15395	COG0516	GMP reductase activity
AN479_RS15395	COG0517	IMP dehydrogenase activity
AN479_RS15400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AN479_RS15400	COG0519	Catalyzes the synthesis of GMP from XMP
AN479_RS15405	COG3708	Transcriptional regulator
AN479_RS15405	COG2207	Transcriptional regulator
AN479_RS15430	COG0784	Response regulator, receiver
AN479_RS15430	COG5002	protein histidine kinase activity
AN479_RS15430	COG2205	protein histidine kinase activity
AN479_RS15435	COG2197	response regulator
AN479_RS15460	COG1187	pseudouridine synthase activity
AN479_RS15475	COG2814	Major facilitator Superfamily
AN479_RS15485	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AN479_RS15490	COG0351	phosphomethylpyrimidine kinase
AN479_RS15505	COG1349	DNA-binding transcription factor activity
AN479_RS15510	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS15530	COG3730	PTS system glucitol sorbitol-specific
AN479_RS15535	COG1830	Aldolase
AN479_RS15540	COG1802	Transcriptional regulator
AN479_RS15550	COG0246	Mannitol dehydrogenase
AN479_RS15555	COG2271	Major facilitator Superfamily
AN479_RS15560	COG1063	alcohol dehydrogenase
AN479_RS15570	COG1597	lipid kinase activity
AN479_RS15575	COG0826	peptidase U32
AN479_RS15580	COG3422	double-strand break repair
AN479_RS15590	COG0745	RESPONSE REGULATOR receiver
AN479_RS15595	COG2205	protein histidine kinase activity
AN479_RS15600	COG2814	Major facilitator Superfamily
AN479_RS15605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN479_RS15610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN479_RS15615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN479_RS15620	COG0667	Aldo Keto reductase
AN479_RS15635	COG0443	Heat shock 70 kDa protein
AN479_RS15650	COG0300	oxidoreductase activity
AN479_RS15665	COG5002	protein histidine kinase activity
AN479_RS15665	COG5001	Diguanylate cyclase
AN479_RS15665	COG3447	MASE1 domain protein
AN479_RS15670	COG2239	Acts as a magnesium transporter
AN479_RS15685	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AN479_RS15690	COG0573	inorganic phosphate transmembrane transporter activity
AN479_RS15695	COG0573	inorganic phosphate transmembrane transporter activity
AN479_RS15710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN479_RS15730	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AN479_RS15730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN479_RS15755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN479_RS15800	COG1131	(ABC) transporter
AN479_RS15805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AN479_RS15810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AN479_RS15815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AN479_RS15820	COG2233	PERMEase
AN479_RS15825	COG2261	transglycosylase associated protein
AN479_RS15835	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AN479_RS15850	COG1393	Belongs to the ArsC family
AN479_RS15855	COG4783	chaperone-mediated protein folding
AN479_RS15905	COG0628	permease
AN479_RS15910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AN479_RS15920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN479_RS15925	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AN479_RS15930	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AN479_RS15935	COG2321	neutral zinc metallopeptidase
AN479_RS15940	COG1444	tRNA N-acetyltransferase activity
AN479_RS15945	COG0400	carboxylic ester hydrolase activity
AN479_RS15955	COG1876	peptidase activity
AN479_RS15960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN479_RS15965	COG1393	Belongs to the ArsC family
AN479_RS15985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN479_RS15995	COG2197	response regulator
AN479_RS16000	COG3850	Histidine kinase
AN479_RS16005	COG0494	nUDIX hydrolase
AN479_RS16010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AN479_RS16015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AN479_RS16020	COG0698	ribose 5-phosphate isomerase
AN479_RS16025	COG1063	alcohol dehydrogenase
AN479_RS16030	COG2814	Major facilitator Superfamily
AN479_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS16040	COG2376	Dihydroxyacetone kinase
AN479_RS16055	COG3397	chitin binding
AN479_RS16060	COG0583	DNA-binding transcription factor activity
AN479_RS16090	COG2040	homocysteine
AN479_RS16095	COG0833	amino acid
AN479_RS16110	COG1770	oligopeptidase
AN479_RS16120	COG1671	Belongs to the UPF0178 family
AN479_RS16125	COG0408	coproporphyrinogen oxidase activity
AN479_RS16130	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN479_RS16135	COG0456	acetyltransferase
AN479_RS16140	COG3111	PFAM Bacterial OB fold (BOF) protein
AN479_RS16155	COG2837	iron assimilation
AN479_RS16165	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AN479_RS16170	COG4208	sulfate ABC transporter
AN479_RS16185	COG0745	RESPONSE REGULATOR receiver
AN479_RS16190	COG2205	protein histidine kinase activity
AN479_RS16200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN479_RS16205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS16215	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AN479_RS16220	COG3115	cell septum assembly
AN479_RS16225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AN479_RS16230	COG3530	Putative quorum-sensing-regulated virulence factor
AN479_RS16235	COG0385	Bile acid
AN479_RS16240	COG0583	DNA-binding transcription factor activity
AN479_RS16255	COG4303	Ethanolamine ammonia lyase large subunit
AN479_RS16260	COG4302	ethanolamine ammonia-lyase activity
AN479_RS16285	COG0747	negative chemotaxis
AN479_RS16290	COG1120	ATPase activity
AN479_RS16295	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN479_RS16300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN479_RS16305	COG4592	Periplasmic binding protein
AN479_RS16335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN479_RS16340	COG2116	formate transmembrane transporter activity
AN479_RS16355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN479_RS16360	COG1914	H( )-stimulated, divalent metal cation uptake system
AN479_RS16370	COG0667	Aldo Keto reductase
AN479_RS16375	COG3961	Belongs to the TPP enzyme family
AN479_RS16390	COG1794	racemase activity, acting on amino acids and derivatives
AN479_RS16395	COG0038	chloride channel
AN479_RS16405	COG2223	nitrite transmembrane transporter activity
AN479_RS16415	COG3279	Response regulator of the LytR AlgR family
AN479_RS16420	COG3275	phosphorelay sensor kinase activity
AN479_RS16435	COG0436	Aminotransferase
AN479_RS16440	COG3038	cytochrome b561
AN479_RS16450	COG1598	PFAM Uncharacterised protein family UPF0150
AN479_RS16460	COG2951	lytic endotransglycosylase activity
AN479_RS16475	COG0697	spore germination
AN479_RS16485	COG0583	DNA-binding transcription factor activity
AN479_RS16495	COG2197	response regulator
AN479_RS16510	COG2207	Transcriptional regulator
AN479_RS16510	COG3708	Transcriptional regulator
AN479_RS16545	COG2116	formate transmembrane transporter activity
AN479_RS16555	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AN479_RS16560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AN479_RS16565	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AN479_RS16570	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AN479_RS16575	COG1138	Cytochrome C-type biogenesis protein
AN479_RS16580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN479_RS16585	COG3088	subunit of a heme lyase
AN479_RS16585	COG4235	cytochrome complex assembly
AN479_RS16590	COG4235	cytochrome complex assembly
AN479_RS16590	COG3088	subunit of a heme lyase
AN479_RS16605	COG3691	Protein conserved in bacteria
AN479_RS16610	COG0183	Belongs to the thiolase family
AN479_RS16615	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN479_RS16615	COG1024	Enoyl-CoA hydratase
AN479_RS16620	COG2062	phosphohistidine phosphatase, SixA
AN479_RS16625	COG2840	Smr protein MutS2
AN479_RS16630	COG2890	protein-(glutamine-N5) methyltransferase activity
AN479_RS16635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AN479_RS16640	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AN479_RS16645	COG0730	response to heat
AN479_RS16650	COG3101	peptidyl-lysine hydroxylation
AN479_RS16660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN479_RS16660	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AN479_RS16665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN479_RS16680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AN479_RS16685	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN479_RS16725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN479_RS16730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN479_RS16770	COG0642	Histidine kinase
AN479_RS16775	COG0697	spore germination
AN479_RS16785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN479_RS16790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AN479_RS16800	COG0586	Pfam SNARE associated Golgi protein
AN479_RS16805	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AN479_RS16810	COG0285	dihydrofolate synthase activity
AN479_RS16815	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AN479_RS16820	COG1286	toxin biosynthetic process
AN479_RS16825	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AN479_RS16830	COG0163	prenyltransferase activity
AN479_RS16835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN479_RS16840	COG4215	(ABC) transporter
AN479_RS16850	COG4598	ABC transporter
AN479_RS16855	COG1090	epimerase
AN479_RS16860	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AN479_RS16865	COG0625	glutathione transferase activity
AN479_RS16870	COG0622	Phosphoesterase
AN479_RS16875	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AN479_RS16880	COG1609	Transcriptional regulator
AN479_RS16885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS16895	COG3037	sugar-specific permease SgaT UlaA
AN479_RS16900	COG3959	Transketolase, thiamine diphosphate binding domain
AN479_RS16905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AN479_RS16920	COG0280	phosphate acetyltransferase
AN479_RS16920	COG0857	belongs to the CobB CobQ family
AN479_RS16925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AN479_RS16930	COG3092	negative regulation of chromosome organization
AN479_RS16935	COG3013	Belongs to the UPF0304 family
AN479_RS16940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN479_RS16945	COG0471	metal ion transport
AN479_RS16945	COG0490	domain, Protein
AN479_RS16950	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AN479_RS16955	COG0436	Aminotransferase
AN479_RS16960	COG0583	DNA-binding transcription factor activity
AN479_RS16965	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AN479_RS16970	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AN479_RS16975	COG0649	NAD binding
AN479_RS16975	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AN479_RS16990	COG1034	ATP synthesis coupled electron transport
AN479_RS16995	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AN479_RS17005	COG0839	Belongs to the complex I subunit 6 family
AN479_RS17010	COG0713	ATP synthesis coupled electron transport
AN479_RS17015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN479_RS17020	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AN479_RS17025	COG1007	ATP synthesis coupled electron transport
AN479_RS17045	COG1609	Transcriptional regulator
AN479_RS17050	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS17055	COG1063	alcohol dehydrogenase
AN479_RS17060	COG4575	ribosome binding
AN479_RS17065	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AN479_RS17070	COG0596	Alpha beta hydrolase
AN479_RS17075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AN479_RS17085	COG0318	PFAM AMP-dependent synthetase and ligase
AN479_RS17100	COG0814	amino acid
AN479_RS17125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN479_RS17135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN479_RS17140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AN479_RS17150	COG0784	Response regulator, receiver
AN479_RS17150	COG2205	protein histidine kinase activity
AN479_RS17155	COG2197	response regulator
AN479_RS17160	COG0642	Histidine kinase
AN479_RS17160	COG2198	Histidine kinase
AN479_RS17165	COG2223	nitrite transmembrane transporter activity
AN479_RS17180	COG0346	lactoylglutathione lyase activity
AN479_RS17195	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN479_RS17210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AN479_RS17210	COG2755	lipolytic protein G-D-S-L family
AN479_RS17225	COG2271	Major facilitator Superfamily
AN479_RS17240	COG0625	glutathione transferase activity
AN479_RS17250	COG3083	sulfuric ester hydrolase activity
AN479_RS17255	COG3082	Protein of unknown function (DUF1414)
AN479_RS17260	COG3081	Nucleoid-associated protein
AN479_RS17265	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AN479_RS17270	COG1061	Type III restriction enzyme res subunit
AN479_RS17275	COG1187	pseudouridine synthase activity
AN479_RS17280	COG2814	Major facilitator Superfamily
AN479_RS17290	COG4172	Belongs to the ABC transporter superfamily
AN479_RS17295	COG4239	(ABC) transporter, permease
AN479_RS17300	COG4174	ABC transporter (Permease)
AN479_RS17305	COG4166	transmembrane transport
AN479_RS17310	COG2200	EAL domain
AN479_RS17315	COG0791	NLP P60 protein
AN479_RS17320	COG0671	phosphoesterase, PA-phosphatase related
AN479_RS17325	COG0523	cobalamin synthesis protein
AN479_RS17335	COG0246	Mannitol dehydrogenase
AN479_RS17340	COG1312	Catalyzes the dehydration of D-mannonate
AN479_RS17345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AN479_RS17365	COG0243	molybdopterin cofactor binding
AN479_RS17370	COG3005	denitrification pathway
AN479_RS17375	COG0494	nUDIX hydrolase
AN479_RS17380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS17380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS17385	COG1105	Belongs to the carbohydrate kinase PfkB family
AN479_RS17390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AN479_RS17390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN479_RS17390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN479_RS17400	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AN479_RS17405	COG2855	membrane
AN479_RS17415	COG0583	DNA-binding transcription factor activity
AN479_RS17420	COG0833	amino acid
AN479_RS17430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN479_RS17445	COG4771	TonB-dependent receptor
AN479_RS17450	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN479_RS17455	COG1129	ABC transporter
AN479_RS17460	COG1396	sequence-specific DNA binding
AN479_RS17460	COG1917	Cupin 2, conserved barrel domain protein
AN479_RS17465	COG0174	glutamine synthetase
AN479_RS17470	COG0531	amino acid
AN479_RS17475	COG2925	Exonuclease
AN479_RS17500	COG3023	N-Acetylmuramoyl-L-alanine amidase
AN479_RS17505	COG1289	transmembrane transporter activity
AN479_RS17510	COG2926	Belongs to the UPF0265 family
AN479_RS17515	COG1063	alcohol dehydrogenase
AN479_RS17520	COG1879	ABC-type sugar transport system periplasmic component
AN479_RS17530	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN479_RS17535	COG1070	Carbohydrate kinase
AN479_RS17540	COG3623	hexulose-6-phosphate isomerase
AN479_RS17550	COG1609	Transcriptional regulator
AN479_RS17565	COG0583	DNA-binding transcription factor activity
AN479_RS17590	COG0795	lipopolysaccharide-transporting ATPase activity
AN479_RS17595	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AN479_RS17605	COG2244	polysaccharide biosynthetic process
AN479_RS17610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AN479_RS17615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AN479_RS17620	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AN479_RS17625	COG0156	8-amino-7-oxononanoate synthase activity
AN479_RS17630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN479_RS17645	COG0456	acetyltransferase
AN479_RS17655	COG0583	DNA-binding transcription factor activity
AN479_RS17720	COG0411	ABC transporter
AN479_RS17750	COG2271	Major facilitator Superfamily
AN479_RS17770	COG2070	2-Nitropropane dioxygenase
AN479_RS17790	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AN479_RS17795	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS17815	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN479_RS17820	COG2814	Major facilitator Superfamily
AN479_RS17835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN479_RS17840	COG1121	(ABC) transporter
AN479_RS17850	COG2197	response regulator
AN479_RS17855	COG0583	DNA-binding transcription factor activity
AN479_RS17895	COG2207	Transcriptional regulator
AN479_RS17900	COG0300	oxidoreductase activity
AN479_RS17910	COG3250	beta-galactosidase activity
AN479_RS17915	COG4565	transcriptional regulatory protein
AN479_RS17920	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AN479_RS17925	COG3052	prosthetic group binding
AN479_RS17930	COG2301	Belongs to the HpcH HpaI aldolase family
AN479_RS17935	COG3051	citrate lyase alpha subunit
AN479_RS17945	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AN479_RS17950	COG0471	metal ion transport
AN479_RS17965	COG1169	isochorismate synthase
AN479_RS17970	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS17990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AN479_RS18000	COG0463	Glycosyl transferase, family 2
AN479_RS18005	COG0025	NhaP-type Na H and K H
AN479_RS18010	COG4993	Dehydrogenase
AN479_RS18030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN479_RS18045	COG0583	DNA-binding transcription factor activity
AN479_RS18065	COG1247	-acetyltransferase
AN479_RS18070	COG3238	Protein conserved in bacteria
AN479_RS18085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AN479_RS18100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN479_RS18105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN479_RS18110	COG1116	anion transmembrane transporter activity
AN479_RS18115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AN479_RS18120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN479_RS18130	COG4977	sequence-specific DNA binding
AN479_RS18135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN479_RS18145	COG3228	Belongs to the MtfA family
AN479_RS18165	COG3485	protocatechuate 3,4-dioxygenase
AN479_RS18170	COG3485	protocatechuate 3,4-dioxygenase
AN479_RS18175	COG0583	DNA-binding transcription factor activity
AN479_RS18180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AN479_RS18190	COG0183	Belongs to the thiolase family
AN479_RS18195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN479_RS18200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN479_RS18205	COG1414	Transcriptional regulator
AN479_RS18320	COG2197	response regulator
AN479_RS18335	COG0561	phosphatase activity
AN479_RS18400	COG0534	Mate efflux family protein
AN479_RS18410	COG3539	Fimbrial protein
AN479_RS18415	COG3188	usher protein
AN479_RS18420	COG3121	Chaperone
AN479_RS18430	COG3539	Fimbrial protein
AN479_RS18465	COG4993	Dehydrogenase
AN479_RS18470	COG4772	TonB-dependent receptor
AN479_RS18480	COG0667	Aldo Keto reductase
AN479_RS18520	COG0625	glutathione transferase activity
AN479_RS18525	COG0583	DNA-binding transcription factor activity
AN479_RS18545	COG1113	amino acid transport
AN479_RS18550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AN479_RS18555	COG3327	negative regulation of DNA-templated transcription, initiation
AN479_RS18560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AN479_RS18565	COG0183	Belongs to the thiolase family
AN479_RS18570	COG2050	protein possibly involved in aromatic compounds catabolism
AN479_RS18575	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN479_RS18580	COG1024	Enoyl-CoA hydratase
AN479_RS18585	COG1024	Enoyl-CoA hydratase
AN479_RS18590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN479_RS18595	COG2151	metal-sulfur cluster biosynthetic enzyme
AN479_RS18600	COG3396	Phenylacetate-CoA oxygenase
AN479_RS18605	COG3460	Phenylacetate-CoA oxygenase
AN479_RS18610	COG3396	Phenylacetate-CoA oxygenase
AN479_RS18615	COG2030	dehydratase
AN479_RS18615	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS18625	COG2203	Gaf domain
AN479_RS18625	COG3706	GGDEF domain
AN479_RS18625	COG4251	negative regulation of phosphorylation
AN479_RS18625	COG5001	Diguanylate cyclase
AN479_RS18635	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AN479_RS18640	COG1560	Kdo2-lipid A biosynthetic process
AN479_RS18650	COG2261	transglycosylase associated protein
AN479_RS18655	COG3753	Protein conserved in bacteria
AN479_RS18660	COG0583	DNA-binding transcription factor activity
AN479_RS18670	COG3321	synthase
AN479_RS18670	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS18670	COG0604	alcohol dehydrogenase
AN479_RS18705	COG0076	glutamate decarboxylase activity
AN479_RS18715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AN479_RS18725	COG1285	pathogenesis
AN479_RS18750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AN479_RS18760	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AN479_RS18765	COG1393	Belongs to the ArsC family
AN479_RS18770	COG2837	iron assimilation
AN479_RS18775	COG3781	membrane
AN479_RS18790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AN479_RS18795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN479_RS18840	COG3483	tryptophan 2,3-dioxygenase activity
AN479_RS18845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AN479_RS19015	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AN479_RS19020	COG2130	NADP-dependent
AN479_RS19025	COG0589	response to stress
AN479_RS19060	COG0643	Histidine kinase
AN479_RS19060	COG2198	Histidine kinase
AN479_RS19065	COG0835	chemotaxis
AN479_RS19070	COG0840	transmembrane signaling receptor activity
AN479_RS19075	COG0840	transmembrane signaling receptor activity
AN479_RS19080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AN479_RS19090	COG0745	RESPONSE REGULATOR receiver
AN479_RS19095	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AN479_RS19100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AN479_RS19105	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AN479_RS19125	COG3418	PFAM FlgN family protein
AN479_RS19130	COG2747	anti-sigma28 factor FlgM
AN479_RS19140	COG1815	bacterial-type flagellum-dependent cell motility
AN479_RS19145	COG1558	bacterial-type flagellum-dependent cell motility
AN479_RS19150	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AN479_RS19185	COG1256	bacterial-type flagellum assembly
AN479_RS19235	COG2882	bacterial-type flagellum organization
AN479_RS19240	COG1157	protein secretion by the type III secretion system
AN479_RS19245	COG1317	bacterial-type flagellum organization
AN479_RS19250	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AN479_RS19260	COG1677	Flagellar hook-basal body complex protein FliE
AN479_RS19275	COG0583	DNA-binding transcription factor activity
AN479_RS19305	COG1191	sigma factor activity
AN479_RS19315	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AN479_RS19320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN479_RS19325	COG0765	amino acid transport
AN479_RS19330	COG1126	abc transporter atp-binding protein
AN479_RS19335	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AN479_RS19335	COG0506	proline dehydrogenase activity
AN479_RS19335	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AN479_RS19345	COG0672	)-iron permease
AN479_RS19350	COG2822	iron ion transport
AN479_RS19360	COG1702	phosphate starvation-inducible protein PhoH
AN479_RS19370	COG0387	Pfam Sodium calcium exchanger
AN479_RS19375	COG2375	cellular response to nickel ion
AN479_RS19380	COG4572	Cation transport regulator
AN479_RS19385	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AN479_RS19390	COG0583	DNA-binding transcription factor activity
AN479_RS19410	COG0601	transmembrane transport
AN479_RS19415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN479_RS19420	COG0444	Belongs to the ABC transporter superfamily
AN479_RS19425	COG4608	Belongs to the ABC transporter superfamily
AN479_RS19440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AN479_RS19445	COG4932	domain protein
AN479_RS19450	COG2197	response regulator
AN479_RS19455	COG3850	Histidine kinase
AN479_RS19460	COG2223	nitrite transmembrane transporter activity
AN479_RS19465	COG3710	Transcriptional regulator
AN479_RS19470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN479_RS19475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN479_RS19485	COG3206	protein involved in exopolysaccharide biosynthesis
AN479_RS19485	COG0489	protein tyrosine kinase activity
AN479_RS19510	COG1216	Glycosyl transferase, family 2
AN479_RS19520	COG1216	Glycosyl transferase, family 2
AN479_RS19525	COG1215	transferase activity, transferring glycosyl groups
AN479_RS19530	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AN479_RS19535	COG1140	nitrate reductase beta subunit
AN479_RS19540	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AN479_RS19545	COG2181	nitrate reductase activity
AN479_RS19550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN479_RS19555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN479_RS19600	COG1294	oxidase, subunit
AN479_RS19605	COG1271	oxidase subunit
AN479_RS19610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN479_RS19620	COG0601	transmembrane transport
AN479_RS19630	COG0444	Belongs to the ABC transporter superfamily
AN479_RS19635	COG4608	Belongs to the ABC transporter superfamily
AN479_RS19645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN479_RS19650	COG3138	arginine N-succinyltransferase
AN479_RS19655	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS19660	COG3724	N-succinylarginine dihydrolase activity
AN479_RS19665	COG2988	succinylglutamate desuccinylase activity
AN479_RS19685	COG1652	LysM domain
AN479_RS19700	COG2207	Transcriptional regulator
AN479_RS19745	COG1113	amino acid transport
AN479_RS19765	COG1496	oxidoreductase activity
AN479_RS19770	COG2226	methyltransferase
AN479_RS19775	COG1971	Probably functions as a manganese efflux pump
AN479_RS19780	COG4811	Protein of unknown function (DUF986)
AN479_RS19785	COG3716	PTS system mannose fructose sorbose family IID component
AN479_RS19790	COG3715	PTS system
AN479_RS19795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN479_RS19795	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN479_RS19800	COG1253	flavin adenine dinucleotide binding
AN479_RS19805	COG2200	EAL domain
AN479_RS19810	COG1760	l-serine dehydratase
AN479_RS19815	COG0494	nUDIX hydrolase
AN479_RS19825	COG1216	Glycosyl transferase, family 2
AN479_RS19830	COG3140	Belongs to the UPF0181 family
AN479_RS19835	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AN479_RS19845	COG0513	Belongs to the DEAD box helicase family
AN479_RS19850	COG3141	response to X-ray
AN479_RS19855	COG3097	Belongs to the UPF0267 family
AN479_RS19875	COG2999	glutathione oxidoreductase activity
AN479_RS19885	COG0477	Major facilitator Superfamily
AN479_RS19890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN479_RS19895	COG3132	Protein of unknown function, DUF480
AN479_RS19900	COG0673	inositol 2-dehydrogenase activity
AN479_RS19910	COG0018	arginyl-trna synthetase
AN479_RS19915	COG3102	Protein conserved in bacteria
AN479_RS19920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AN479_RS19925	COG3142	Participates in the control of copper homeostasis
AN479_RS19940	COG0545	Peptidyl-prolyl cis-trans isomerase
AN479_RS19945	COG0500	methyltransferase
AN479_RS19950	COG2226	methyltransferase
AN479_RS19955	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AN479_RS19960	COG1801	Protein of unknown function DUF72
AN479_RS19965	COG1335	isochorismatase
AN479_RS19970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AN479_RS19975	COG0494	nUDIX hydrolase
AN479_RS19980	COG0217	transcriptional regulatory protein
AN479_RS19985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AN479_RS19990	COG0632	four-way junction helicase activity
AN479_RS19995	COG2255	four-way junction helicase activity
AN479_RS20000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN479_RS20005	COG1121	(ABC) transporter
AN479_RS20010	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AN479_RS20015	COG0739	heme binding
AN479_RS20020	COG1560	Kdo2-lipid A biosynthetic process
AN479_RS20030	COG0469	pyruvate kinase activity
AN479_RS20035	COG1737	Transcriptional regulator
AN479_RS20040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AN479_RS20045	COG0800	Aldolase
AN479_RS20050	COG2076	Multidrug Resistance protein
AN479_RS20055	COG2076	Multidrug Resistance protein
AN479_RS20060	COG0251	oxidation-reduction process
AN479_RS20065	COG1199	ATP-dependent helicase activity
AN479_RS20075	COG3065	identical protein binding
AN479_RS20080	COG0318	PFAM AMP-dependent synthetase and ligase
AN479_RS20085	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AN479_RS20090	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AN479_RS20095	COG2894	cell division
AN479_RS20100	COG0850	regulation of cytokinetic process
AN479_RS20105	COG3100	YcgL domain-containing protein
AN479_RS20110	COG2951	lytic endotransglycosylase activity
AN479_RS20115	COG0179	Fumarylacetoacetate (FAA) hydrolase
AN479_RS20120	COG2983	Belongs to the UPF0260 family
AN479_RS20130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AN479_RS20135	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AN479_RS20140	COG2186	Transcriptional regulator
AN479_RS20145	COG2719	SpoVR family
AN479_RS20150	COG3443	Belongs to the bacterial solute-binding protein 9 family
AN479_RS20160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN479_RS20165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN479_RS20205	COG2718	Belongs to the UPF0229 family
AN479_RS20210	COG2766	serine protein kinase
AN479_RS20215	COG3713	MltA-interacting MipA family protein
AN479_RS20230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN479_RS20235	COG3139	Protein of unknown function (DUF1315)
AN479_RS20245	COG1335	isochorismatase
AN479_RS20250	COG0252	asparaginase activity
AN479_RS20255	COG0616	signal peptide processing
AN479_RS20260	COG0778	Nitroreductase
AN479_RS20270	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AN479_RS20275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AN479_RS20285	COG0494	nUDIX hydrolase
AN479_RS20290	COG0708	Exodeoxyribonuclease III
AN479_RS20310	COG0788	formyltetrahydrofolate deformylase activity
AN479_RS20315	COG3012	SEC-C Motif Domain Protein
AN479_RS20320	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN479_RS20325	COG0745	RESPONSE REGULATOR receiver
AN479_RS20330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN479_RS20355	COG1454	alcohol dehydrogenase
AN479_RS20355	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS20360	COG2095	MarC family integral membrane protein
AN479_RS20365	COG4166	transmembrane transport
AN479_RS20380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN479_RS20385	COG0444	Belongs to the ABC transporter superfamily
AN479_RS20395	COG3099	Belongs to the UPF0263 family
AN479_RS20400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN479_RS20410	COG0783	Belongs to the Dps family
AN479_RS20425	COG1879	ABC-type sugar transport system periplasmic component
AN479_RS20430	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN479_RS20435	COG1129	ABC transporter
AN479_RS20440	COG1070	Carbohydrate kinase
AN479_RS20455	COG1609	Transcriptional regulator
AN479_RS20465	COG0583	DNA-binding transcription factor activity
AN479_RS20470	COG2350	Protein conserved in bacteria
AN479_RS20475	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AN479_RS20485	COG1607	acyl-coa hydrolase
AN479_RS20490	COG2917	probably involved in intracellular septation
AN479_RS20505	COG0727	PFAM Uncharacterised protein family (UPF0153)
AN479_RS20520	COG0159	tryptophan synthase activity
AN479_RS20525	COG0133	tryptophan synthase activity
AN479_RS20535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AN479_RS20550	COG0613	PHP domain protein
AN479_RS20555	COG0009	L-threonylcarbamoyladenylate synthase
AN479_RS20565	COG0596	Alpha beta hydrolase
AN479_RS20565	COG2945	thiolester hydrolase activity
AN479_RS20570	COG1187	pseudouridine synthase activity
AN479_RS20575	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AN479_RS20580	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS20585	COG0616	signal peptide processing
AN479_RS20600	COG0583	DNA-binding transcription factor activity
AN479_RS20610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AN479_RS20620	COG0671	phosphoesterase, PA-phosphatase related
AN479_RS20625	COG1349	DNA-binding transcription factor activity
AN479_RS20630	COG3959	Transketolase, thiamine diphosphate binding domain
AN479_RS20635	COG3958	Transketolase
AN479_RS20640	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS20655	COG1129	ABC transporter
AN479_RS20660	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN479_RS20665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AN479_RS20670	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS20675	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AN479_RS20680	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AN479_RS20700	COG0023	Translation Initiation Factor
AN479_RS20710	COG1349	DNA-binding transcription factor activity
AN479_RS20715	COG1882	Formate acetyltransferase
AN479_RS20720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AN479_RS20725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AN479_RS20730	COG1966	Carbon starvation protein
AN479_RS20735	COG1473	amidohydrolase
AN479_RS20740	COG0477	Major facilitator Superfamily
AN479_RS20745	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AN479_RS20760	COG0243	molybdopterin cofactor binding
AN479_RS20780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN479_RS20780	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN479_RS20790	COG4172	Belongs to the ABC transporter superfamily
AN479_RS20795	COG4172	Belongs to the ABC transporter superfamily
AN479_RS20800	COG4171	peptide transport system, permease
AN479_RS20815	COG1469	GTP cyclohydrolase I activity
AN479_RS20830	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS20840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AN479_RS20845	COG1842	Phage shock protein A
AN479_RS20855	COG1983	PspC domain protein
AN479_RS20865	COG3106	COG3106 Predicted ATPase
AN479_RS20870	COG3768	UPF0283 membrane protein
AN479_RS20880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AN479_RS20885	COG4948	Mandelate Racemase Muconate Lactonizing
AN479_RS20890	COG2866	Carboxypeptidase
AN479_RS20900	COG4166	transmembrane transport
AN479_RS20930	COG0037	tRNA processing
AN479_RS20935	COG0674	pyruvate-flavodoxin oxidoreductase activity
AN479_RS20935	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AN479_RS20935	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AN479_RS20935	COG1013	pyruvate-flavodoxin oxidoreductase activity
AN479_RS20945	COG3042	response to heat
AN479_RS20950	COG3187	Heat shock protein
AN479_RS20955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AN479_RS20960	COG2911	Protein conserved in bacteria
AN479_RS20970	COG3784	Protein of unknown function (DUF1318)
AN479_RS20975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AN479_RS20980	COG1643	Atp-dependent helicase
AN479_RS20985	COG3591	Belongs to the peptidase S1B family
AN479_RS21000	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AN479_RS21005	COG2205	protein histidine kinase activity
AN479_RS21010	COG0745	RESPONSE REGULATOR receiver
AN479_RS21035	COG0531	amino acid
AN479_RS21045	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AN479_RS21050	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AN479_RS21055	COG0589	response to stress
AN479_RS21065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN479_RS21080	COG2222	sugar isomerase
AN479_RS21095	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AN479_RS21100	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AN479_RS21120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN479_RS21200	COG3158	transport of potassium into the cell
AN479_RS21205	COG0363	glucosamine-6-phosphate deaminase activity
AN479_RS21255	COG0697	spore germination
AN479_RS21260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AN479_RS21310	COG2239	Acts as a magnesium transporter
AN479_RS21320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN479_RS21330	COG0488	(ABC) transporter
AN479_RS21335	COG3264	Mechanosensitive ion channel
AN479_RS21335	COG1196	nuclear chromosome segregation
AN479_RS21355	COG2199	diguanylate cyclase activity
AN479_RS21360	COG5507	3-demethylubiquinone-9 3-methyltransferase
AN479_RS21375	COG3048	D-serine ammonia-lyase activity
AN479_RS21380	COG2814	Major facilitator Superfamily
AN479_RS21390	COG2723	6-phospho-beta-galactosidase activity
AN479_RS21395	COG1737	Transcriptional regulator
AN479_RS21400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN479_RS21415	COG2080	2 iron, 2 sulfur cluster binding
AN479_RS21420	COG2010	Cytochrome c
AN479_RS21420	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AN479_RS21425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AN479_RS21425	COG2010	Cytochrome c
AN479_RS21430	COG0778	Nitroreductase
AN479_RS21455	COG3192	ethanolamine utilization protein
AN479_RS21460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AN479_RS21475	COG1349	DNA-binding transcription factor activity
AN479_RS21480	COG0243	molybdopterin cofactor binding
AN479_RS21490	COG0583	DNA-binding transcription factor activity
AN479_RS21495	COG2957	Belongs to the agmatine deiminase family
AN479_RS21515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN479_RS21530	COG0693	protein deglycase activity
AN479_RS21535	COG0318	PFAM AMP-dependent synthetase and ligase
AN479_RS21540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN479_RS21555	COG4774	siderophore transport
AN479_RS21560	COG2382	esterase
AN479_RS21575	COG0477	Major facilitator Superfamily
AN479_RS21580	COG1733	regulation of RNA biosynthetic process
AN479_RS21585	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN479_RS21590	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN479_RS21630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AN479_RS21690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN479_RS21710	COG4774	siderophore transport
AN479_RS21720	COG1309	transcriptional regulator
AN479_RS21725	COG0477	Major facilitator Superfamily
AN479_RS21735	COG0640	Transcriptional regulator
AN479_RS21750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN479_RS21775	COG0583	DNA-binding transcription factor activity
AN479_RS21790	COG5002	protein histidine kinase activity
AN479_RS21790	COG5001	Diguanylate cyclase
AN479_RS21790	COG3447	MASE1 domain protein
AN479_RS21795	COG1227	inorganic diphosphatase activity
AN479_RS21805	COG0148	phosphopyruvate hydratase activity
AN479_RS21810	COG0789	Transcriptional regulator
AN479_RS21815	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN479_RS21815	COG1902	pentaerythritol trinitrate reductase activity
AN479_RS21820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN479_RS21825	COG0076	glutamate decarboxylase activity
AN479_RS21835	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AN479_RS21890	COG4993	Dehydrogenase
AN479_RS21905	COG3300	MHYT domain
AN479_RS21905	COG5001	Diguanylate cyclase
AN479_RS21920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN479_RS21930	COG2223	nitrite transmembrane transporter activity
AN479_RS21940	COG2814	Major facilitator Superfamily
AN479_RS21950	COG3284	Transcriptional regulator
AN479_RS21960	COG1064	alcohol dehydrogenase
AN479_RS21975	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN479_RS21985	COG0583	DNA-binding transcription factor activity
AN479_RS21990	COG2814	Major facilitator Superfamily
AN479_RS21995	COG2862	Uncharacterized protein family, UPF0114
AN479_RS22000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AN479_RS22025	COG2814	Major facilitator Superfamily
AN479_RS22030	COG0673	inositol 2-dehydrogenase activity
AN479_RS22035	COG1349	DNA-binding transcription factor activity
AN479_RS22065	COG0768	penicillin binding
AN479_RS22085	COG2814	Major facilitator Superfamily
AN479_RS22105	COG2169	Transcriptional regulator
AN479_RS22105	COG1917	Cupin 2, conserved barrel domain protein
AN479_RS22150	COG0596	Alpha beta hydrolase
AN479_RS22175	COG2059	Chromate
AN479_RS22185	COG2140	Oxalate decarboxylase
AN479_RS22235	COG0583	DNA-binding transcription factor activity
AN479_RS22245	COG2080	2 iron, 2 sulfur cluster binding
AN479_RS22250	COG1846	Transcriptional regulator
AN479_RS22255	COG2309	aminopeptidase activity
AN479_RS22260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN479_RS22265	COG0596	Alpha beta hydrolase
AN479_RS22270	COG3473	Maleate cis-trans isomerase
AN479_RS22275	COG1335	isochorismatase
AN479_RS22280	COG2271	Major facilitator Superfamily
AN479_RS22290	COG0339	signal peptide processing
AN479_RS22295	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AN479_RS22300	COG0402	S-adenosylhomocysteine deaminase activity
AN479_RS22305	COG1595	DNA-templated transcription, initiation
AN479_RS22310	COG3712	iron ion homeostasis
AN479_RS22315	COG4772	TonB-dependent receptor
AN479_RS22325	COG4221	oxidoreductase activity
AN479_RS22330	COG1742	UPF0060 membrane protein
AN479_RS22345	COG0477	Major facilitator Superfamily
AN479_RS22375	COG0789	Transcriptional regulator
AN479_RS22385	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AN479_RS22390	COG1940	carbohydrate kinase activity
AN479_RS22395	COG0583	DNA-binding transcription factor activity
AN479_RS22400	COG2814	Major facilitator Superfamily
AN479_RS22405	COG1649	PFAM Uncharacterised BCR, COG1649
AN479_RS22410	COG1472	Belongs to the glycosyl hydrolase 3 family
AN479_RS22425	COG2378	regulation of single-species biofilm formation
AN479_RS22430	COG0114	fumarate hydratase activity
AN479_RS22445	COG5339	Protein conserved in bacteria
AN479_RS22455	COG0583	DNA-binding transcription factor activity
AN479_RS22470	COG1609	Transcriptional regulator
AN479_RS22475	COG1263	PTS System
AN479_RS22475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN479_RS22480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AN479_RS22490	COG0494	nUDIX hydrolase
AN479_RS22495	COG1349	DNA-binding transcription factor activity
AN479_RS22500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AN479_RS22510	COG0385	Bile acid
AN479_RS22515	COG0673	inositol 2-dehydrogenase activity
AN479_RS22525	COG4657	Part of a membrane complex involved in electron transport
AN479_RS22530	COG2878	Part of a membrane complex involved in electron transport
AN479_RS22535	COG4656	Part of a membrane complex involved in electron transport
AN479_RS22540	COG2207	Transcriptional regulator
AN479_RS22540	COG3708	Transcriptional regulator
AN479_RS22550	COG4659	FMN binding
AN479_RS22560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AN479_RS22565	COG3104	oligopeptide transport
AN479_RS22570	COG1505	serine-type exopeptidase activity
AN479_RS22575	COG1396	sequence-specific DNA binding
AN479_RS22580	COG3135	benzoate transporter
AN479_RS22615	COG1418	mRNA catabolic process
AN479_RS22630	COG0625	glutathione transferase activity
AN479_RS22640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AN479_RS22645	COG0259	pyridoxamine-phosphate oxidase activity
AN479_RS22655	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AN479_RS22660	COG3133	Outer membrane lipoprotein
AN479_RS22665	COG1846	Transcriptional regulator
AN479_RS22670	COG1566	PFAM secretion protein HlyD family protein
AN479_RS22675	COG1289	transmembrane transporter activity
AN479_RS22685	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AN479_RS22690	COG4989	oxidoreductase activity
AN479_RS22695	COG3313	Fe-S protein
AN479_RS22700	COG0583	DNA-binding transcription factor activity
AN479_RS22710	COG2194	sulfuric ester hydrolase activity
AN479_RS22715	COG1309	transcriptional regulator
AN479_RS22720	COG1902	pentaerythritol trinitrate reductase activity
AN479_RS22725	COG0346	lactoylglutathione lyase activity
AN479_RS22735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AN479_RS22740	COG0791	NLP P60 protein
AN479_RS22750	COG1609	Transcriptional regulator
AN479_RS22755	COG0583	DNA-binding transcription factor activity
AN479_RS22760	COG2814	Major facilitator Superfamily
AN479_RS22765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AN479_RS22775	COG0307	riboflavin synthase, alpha
AN479_RS22780	COG0534	Mate efflux family protein
AN479_RS22805	COG0469	pyruvate kinase activity
AN479_RS22815	COG1376	ErfK ybiS ycfS ynhG family protein
AN479_RS22815	COG1388	LysM domain
AN479_RS22820	COG2166	iron-sulfur cluster assembly
AN479_RS22825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN479_RS22830	COG0719	Fe-S assembly protein
AN479_RS22835	COG0396	ATPase activity
AN479_RS22840	COG0719	Fe-S assembly protein
AN479_RS22845	COG0316	Belongs to the HesB IscA family
AN479_RS22855	COG2050	protein possibly involved in aromatic compounds catabolism
AN479_RS22860	COG0247	lactate metabolic process
AN479_RS22860	COG0277	FAD linked oxidase domain protein
AN479_RS22865	COG0628	permease
AN479_RS22875	COG0574	Belongs to the PEP-utilizing enzyme family
AN479_RS22875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN479_RS22885	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AN479_RS22890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN479_RS22895	COG0386	Belongs to the glutathione peroxidase family
AN479_RS22910	COG3720	iron ion transport
AN479_RS22915	COG4558	Periplasmic binding protein
AN479_RS22920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN479_RS22940	COG0095	Lipoate-protein ligase
AN479_RS22945	COG0791	NLP P60 protein
AN479_RS22950	COG2076	Multidrug Resistance protein
AN479_RS22955	COG2076	Multidrug Resistance protein
AN479_RS22960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AN479_RS22965	COG0726	polysaccharide deacetylase
AN479_RS22970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN479_RS22970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AN479_RS22975	COG1215	transferase activity, transferring glycosyl groups
AN479_RS22980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN479_RS22990	COG0386	Belongs to the glutathione peroxidase family
AN479_RS22995	COG4139	cobalamin transport
AN479_RS23015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AN479_RS23020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AN479_RS23025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AN479_RS23035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AN479_RS23065	COG0814	amino acid
AN479_RS23095	COG0803	Belongs to the bacterial solute-binding protein 9 family
AN479_RS23100	COG1121	(ABC) transporter
AN479_RS23105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN479_RS23110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN479_RS23115	COG3001	Fructosamine kinase
AN479_RS23130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN479_RS23135	COG1988	membrane-bound metal-dependent
AN479_RS23140	COG1823	symporter activity
AN479_RS23155	COG2188	Transcriptional regulator
AN479_RS23180	COG1414	Transcriptional regulator
AN479_RS23185	COG2814	Major facilitator Superfamily
AN479_RS23195	COG0501	Belongs to the peptidase M48B family
AN479_RS23200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN479_RS23205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN479_RS23210	COG1120	ATPase activity
AN479_RS23230	COG0793	Belongs to the peptidase S41A family
AN479_RS23235	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AN479_RS23240	COG1956	GAF domain-containing protein
AN479_RS23245	COG2995	paraquat-inducible protein a
AN479_RS23250	COG3008	intermembrane lipid transfer
AN479_RS23255	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AN479_RS23255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AN479_RS23315	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AN479_RS23320	COG3493	citrate carrier protein
AN479_RS23325	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AN479_RS23345	COG0477	Major facilitator Superfamily
AN479_RS23350	COG2211	Major facilitator Superfamily
AN479_RS23370	COG0402	S-adenosylhomocysteine deaminase activity
AN479_RS23380	COG1228	amidohydrolase
AN479_RS23395	COG1605	Chorismate mutase
AN479_RS23425	COG0531	amino acid
AN479_RS23430	COG0174	glutamine synthetase
AN479_RS23435	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AN479_RS23440	COG1396	sequence-specific DNA binding
AN479_RS23440	COG1917	Cupin 2, conserved barrel domain protein
AN479_RS23445	COG1012	belongs to the aldehyde dehydrogenase family
AN479_RS23450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN479_RS23455	COG1028	Short-chain dehydrogenase reductase Sdr
AN479_RS23460	COG0589	response to stress
AN479_RS23465	COG1335	isochorismatase
AN479_RS23475	COG1278	Cold shock
AN479_RS23540	COG3064	Membrane
AN479_RS23565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN479_RS23670	COG5410	chromosome segregation
AN479_RS23695	COG3772	lysozyme
AN479_RS23715	COG1403	HNH endonuclease
AN479_RS23725	COG1846	Transcriptional regulator
AN479_RS23750	COG1475	DNA binding
AN479_RS23765	COG0582	viral genome integration into host DNA