locus-tag	class	description
FG173_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FG173_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FG173_RS00020	COG0187	DNA topoisomerase II activity
FG173_RS00025	COG0561	phosphatase activity
FG173_RS00030	COG2423	ornithine cyclodeaminase activity
FG173_RS00035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FG173_RS00050	COG5645	(Lipo)protein
FG173_RS00055	COG0071	Belongs to the small heat shock protein (HSP20) family
FG173_RS00060	COG0071	Belongs to the small heat shock protein (HSP20) family
FG173_RS00065	COG2985	domain, Protein
FG173_RS00080	COG3977	Valine--pyruvate aminotransferase
FG173_RS00085	COG0366	Alpha amylase catalytic
FG173_RS00095	COG2814	Major facilitator Superfamily
FG173_RS00115	COG2885	chlorophyll binding
FG173_RS00125	COG2818	Glycosylase
FG173_RS00135	COG0752	glycyl-tRNA synthetase alpha subunit
FG173_RS00140	COG0751	glycine-tRNA ligase activity
FG173_RS00150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FG173_RS00150	COG2213	PTS system mannitol-specific
FG173_RS00155	COG0246	Mannitol dehydrogenase
FG173_RS00160	COG3722	fumarate hydratase activity
FG173_RS00170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FG173_RS00185	COG2258	MOSC domain
FG173_RS00190	COG0840	transmembrane signaling receptor activity
FG173_RS00205	COG0437	4 iron, 4 sulfur cluster binding
FG173_RS00210	COG2864	formate dehydrogenase
FG173_RS00215	COG3058	Necessary for formate dehydrogenase activity
FG173_RS00255	COG3274	enterobacterial common antigen metabolic process
FG173_RS00265	COG1335	isochorismatase
FG173_RS00270	COG0402	S-adenosylhomocysteine deaminase activity
FG173_RS00275	COG0583	DNA-binding transcription factor activity
FG173_RS00280	COG2807	transmembrane transport
FG173_RS00290	COG0582	viral genome integration into host DNA
FG173_RS00320	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FG173_RS00330	COG1715	Restriction endonuclease
FG173_RS00350	COG3596	GTP binding
FG173_RS00365	COG2003	Belongs to the UPF0758 family
FG173_RS00435	COG2814	Major facilitator Superfamily
FG173_RS00480	COG1846	Transcriptional regulator
FG173_RS00490	COG2194	sulfuric ester hydrolase activity
FG173_RS00495	COG2197	response regulator
FG173_RS00505	COG2271	Major facilitator Superfamily
FG173_RS00525	COG0747	negative chemotaxis
FG173_RS00530	COG0601	transmembrane transport
FG173_RS00535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FG173_RS00540	COG0444	Belongs to the ABC transporter superfamily
FG173_RS00545	COG4608	Belongs to the ABC transporter superfamily
FG173_RS00550	COG2194	sulfuric ester hydrolase activity
FG173_RS00575	COG1215	transferase activity, transferring glycosyl groups
FG173_RS00595	COG2200	EAL domain
FG173_RS00595	COG2199	diguanylate cyclase activity
FG173_RS00600	COG1301	dicarboxylic acid transport
FG173_RS00605	COG0612	Peptidase, M16
FG173_RS00610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FG173_RS00620	COG0248	Ppx GppA phosphatase
FG173_RS00630	COG3118	belongs to the thioredoxin family
FG173_RS00635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FG173_RS00640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FG173_RS00650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FG173_RS00655	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FG173_RS00660	COG1088	dTDP-glucose 4,6-dehydratase activity
FG173_RS00665	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FG173_RS00670	COG0456	acetyltransferase
FG173_RS00675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FG173_RS00680	COG2244	polysaccharide biosynthetic process
FG173_RS00685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FG173_RS00695	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FG173_RS00735	COG3071	HemY protein
FG173_RS00745	COG1587	Uroporphyrinogen-III synthase
FG173_RS00750	COG0181	hydroxymethylbilane synthase activity
FG173_RS00755	COG3072	Adenylate cyclase
FG173_RS00760	COG1965	Belongs to the frataxin family
FG173_RS00765	COG5567	small periplasmic lipoprotein
FG173_RS00770	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FG173_RS00775	COG3159	Protein conserved in bacteria
FG173_RS00785	COG1011	Hydrolase
FG173_RS00790	COG0210	DNA helicase
FG173_RS00810	COG2050	protein possibly involved in aromatic compounds catabolism
FG173_RS00820	COG0514	ATP-dependent DNA helicase (RecQ)
FG173_RS00825	COG1280	lysine exporter protein (LysE YggA)
FG173_RS00830	COG1280	lysine exporter protein (LysE YggA)
FG173_RS00835	COG2267	carboxylic ester hydrolase activity
FG173_RS00840	COG0561	phosphatase activity
FG173_RS00845	COG0584	glycerophosphoryl diester phosphodiesterase
FG173_RS00850	COG2271	Major facilitator Superfamily
FG173_RS00860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FG173_RS00870	COG0247	lactate metabolic process
FG173_RS00885	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FG173_RS00890	COG0425	Belongs to the sulfur carrier protein TusA family
FG173_RS00910	COG3714	YhhN family
FG173_RS00920	COG3776	membrane
FG173_RS00925	COG0742	ribosomal rna small subunit methyltransferase
FG173_RS00935	COG2884	Cell division ATP-binding protein ftsE
FG173_RS00940	COG2177	Part of the ABC transporter FtsEX involved in
FG173_RS00960	COG0456	acetyltransferase
FG173_RS00970	COG0559	Belongs to the binding-protein-dependent transport system permease family
FG173_RS00985	COG0410	ABC transporter
FG173_RS00990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FG173_RS00995	COG1653	transport
FG173_RS01000	COG1175	transmembrane transport
FG173_RS01010	COG3842	ATPase activity
FG173_RS01015	COG0584	glycerophosphoryl diester phosphodiesterase
FG173_RS01045	COG0412	Dienelactone hydrolase
FG173_RS01065	COG1322	Protein conserved in bacteria
FG173_RS01070	COG2226	methyltransferase
FG173_RS01075	COG3165	ubiquinone biosynthetic process from chorismate
FG173_RS01080	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FG173_RS01095	COG0805	protein transport
FG173_RS01100	COG0084	hydrolase, TatD family'
FG173_RS01135	COG1024	Enoyl-CoA hydratase
FG173_RS01135	COG1250	3-hydroxyacyl-CoA dehydrogenase
FG173_RS01145	COG0006	proline dipeptidase activity
FG173_RS01150	COG1739	Uncharacterized protein family UPF0029
FG173_RS01185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FG173_RS01190	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FG173_RS01190	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FG173_RS01195	COG1072	(Pantothenic acid kinase))
FG173_RS01230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FG173_RS01240	COG0250	Participates in transcription elongation, termination and antitermination
FG173_RS01255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FG173_RS01265	COG0085	RNA polymerase activity
FG173_RS01270	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FG173_RS01300	COG2022	thiamine diphosphate biosynthetic process
FG173_RS01305	COG2104	thiamine diphosphate biosynthetic process
FG173_RS01310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FG173_RS01315	COG0352	thiamine-phosphate diphosphorylase activity
FG173_RS01320	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FG173_RS01325	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FG173_RS01330	COG2816	NAD+ diphosphatase activity
FG173_RS01335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FG173_RS01340	COG1515	deoxyribonuclease V activity
FG173_RS01365	COG0138	bifunctional purine biosynthesis protein purh
FG173_RS01395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FG173_RS01400	COG3162	membrane
FG173_RS01405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FG173_RS01410	COG1301	dicarboxylic acid transport
FG173_RS01430	COG1629	transport
FG173_RS01430	COG4774	siderophore transport
FG173_RS01440	COG3391	amine dehydrogenase activity
FG173_RS01445	COG4771	TonB-dependent receptor
FG173_RS01450	COG2382	esterase
FG173_RS01475	COG1021	2,3-dihydroxybenzoate-AMP ligase
FG173_RS01480	COG3433	isochorismatase activity
FG173_RS01480	COG1535	isochorismatase
FG173_RS01490	COG3647	Membrane
FG173_RS01520	COG3188	usher protein
FG173_RS01525	COG3121	Chaperone
FG173_RS01570	COG1309	transcriptional regulator
FG173_RS01575	COG4232	protein-disulfide reductase activity
FG173_RS01585	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FG173_RS01600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FG173_RS01610	COG0840	transmembrane signaling receptor activity
FG173_RS01620	COG1509	lysine 2,3-aminomutase activity
FG173_RS01625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FG173_RS01630	COG5510	response to toxic substance
FG173_RS01635	COG5510	response to toxic substance
FG173_RS01645	COG3040	lipid binding
FG173_RS01650	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FG173_RS01655	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FG173_RS01660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FG173_RS01665	COG1053	succinate dehydrogenase
FG173_RS01670	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FG173_RS01690	COG1162	GTPase activity
FG173_RS01695	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FG173_RS01720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FG173_RS01720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FG173_RS01725	COG0802	atpase or kinase
FG173_RS01735	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FG173_RS01740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FG173_RS01750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FG173_RS01755	COG0330	HflC and HflK could
FG173_RS01760	COG0330	HflC and HflK could
FG173_RS01765	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FG173_RS01770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FG173_RS01775	COG1959	2 iron, 2 sulfur cluster binding
FG173_RS01780	COG0557	exoribonuclease II activity
FG173_RS01785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FG173_RS01790	COG1960	acyl-CoA dehydrogenase activity
FG173_RS01795	COG3766	membrane
FG173_RS01805	COG3650	response to hydrogen peroxide
FG173_RS01830	COG0360	Binds together with S18 to 16S ribosomal RNA
FG173_RS01840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FG173_RS01845	COG0359	binds to the 23S rRNA
FG173_RS01855	COG3061	Opacity-associated protein A
FG173_RS01860	COG0545	Peptidyl-prolyl cis-trans isomerase
FG173_RS01870	COG0737	Belongs to the 5'-nucleotidase family
FG173_RS01880	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FG173_RS01890	COG1253	flavin adenine dinucleotide binding
FG173_RS01895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FG173_RS01900	COG0729	surface antigen
FG173_RS01910	COG2105	PFAM AIG2 family protein
FG173_RS01915	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FG173_RS01925	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FG173_RS01930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FG173_RS01945	COG1438	arginine binding
FG173_RS01950	COG0039	L-malate dehydrogenase activity
FG173_RS01955	COG3423	Transcriptional regulator
FG173_RS01965	COG0142	geranyltranstransferase activity
FG173_RS01970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FG173_RS01975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FG173_RS01980	COG0697	spore germination
FG173_RS01985	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FG173_RS01990	COG0642	Histidine kinase
FG173_RS01995	COG0745	RESPONSE REGULATOR receiver
FG173_RS02000	COG2027	D-alanyl-D-alanine carboxypeptidase
FG173_RS02010	COG1534	Rna-binding protein
FG173_RS02015	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FG173_RS02025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FG173_RS02030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FG173_RS02035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FG173_RS02050	COG0779	Required for maturation of 30S ribosomal subunits
FG173_RS02055	COG0195	Participates in both transcription termination and antitermination
FG173_RS02065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FG173_RS02070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FG173_RS02075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FG173_RS02080	COG1185	polyribonucleotide nucleotidyltransferase activity
FG173_RS02095	COG0513	Belongs to the DEAD box helicase family
FG173_RS02100	COG2391	methyltransferase activity
FG173_RS02105	COG0425	Belongs to the sulfur carrier protein TusA family
FG173_RS02130	COG0826	peptidase U32
FG173_RS02135	COG0826	peptidase U32
FG173_RS02140	COG3154	lipid carrier protein
FG173_RS02145	COG3153	acetyltransferase
FG173_RS02150	COG2827	Endonuclease containing a URI domain
FG173_RS02155	COG0531	amino acid
FG173_RS02160	COG1982	Orn Lys Arg decarboxylase major
FG173_RS02170	COG3787	Belongs to the UPF0306 family
FG173_RS02175	COG0702	epimerase
FG173_RS02180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FG173_RS02190	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FG173_RS02195	COG3454	Phosphonate metabolism
FG173_RS02200	COG4778	phosphonate C-P lyase system protein PhnL
FG173_RS02205	COG4107	phosphonate C-P lyase system protein PhnK
FG173_RS02210	COG3627	carbon phosphorus lyase activity
FG173_RS02215	COG3626	phosphonate metabolism
FG173_RS02220	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FG173_RS02225	COG3624	Phosphonate C-P lyase system protein PhnG
FG173_RS02230	COG2188	Transcriptional regulator
FG173_RS02235	COG0701	Predicted permease
FG173_RS02255	COG0602	queuosine metabolic process
FG173_RS02265	COG0583	DNA-binding transcription factor activity
FG173_RS02270	COG2249	NAD(P)H dehydrogenase (quinone) activity
FG173_RS02275	COG0366	Alpha amylase catalytic
FG173_RS02280	COG1263	PTS System
FG173_RS02280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FG173_RS02295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FG173_RS02315	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FG173_RS02320	COG0540	Belongs to the ATCase OTCase family
FG173_RS02330	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FG173_RS02355	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FG173_RS02360	COG0456	acetyltransferase
FG173_RS02370	COG2927	DNA polymerase III (CHI subunit)
FG173_RS02375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FG173_RS02380	COG0795	lipopolysaccharide-transporting ATPase activity
FG173_RS02385	COG0795	lipopolysaccharide-transporting ATPase activity
FG173_RS02410	COG0738	Major facilitator superfamily
FG173_RS02445	COG3550	peptidyl-serine autophosphorylation
FG173_RS02450	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FG173_RS02495	COG2879	small protein
FG173_RS02505	COG0583	DNA-binding transcription factor activity
FG173_RS02525	COG1116	anion transmembrane transporter activity
FG173_RS02535	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FG173_RS02545	COG0174	glutamine synthetase
FG173_RS02580	COG0583	DNA-binding transcription factor activity
FG173_RS02585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FG173_RS02600	COG1250	3-hydroxyacyl-CoA dehydrogenase
FG173_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS02625	COG2207	Transcriptional regulator
FG173_RS02635	COG2207	Transcriptional regulator
FG173_RS02635	COG3708	Transcriptional regulator
FG173_RS02640	COG1376	ErfK ybiS ycfS ynhG family protein
FG173_RS02645	COG1846	Transcriptional regulator
FG173_RS02655	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FG173_RS02690	COG0811	peptide transport
FG173_RS02725	COG1454	alcohol dehydrogenase
FG173_RS02745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FG173_RS02755	COG2267	carboxylic ester hydrolase activity
FG173_RS02805	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS02810	COG1846	Transcriptional regulator
FG173_RS02825	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS02840	COG3971	2-oxopent-4-enoate hydratase activity
FG173_RS02860	COG2368	4-hydroxyphenylacetate
FG173_RS02865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FG173_RS02870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FG173_RS02875	COG2186	Transcriptional regulator
FG173_RS02880	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS02885	COG0179	Fumarylacetoacetate (FAA) hydrolase
FG173_RS02890	COG4948	Mandelate Racemase Muconate Lactonizing
FG173_RS02895	COG3618	amidohydrolase
FG173_RS02905	COG3254	rhamnose metabolic process
FG173_RS02910	COG0738	Major facilitator superfamily
FG173_RS02960	COG0667	Aldo Keto reductase
FG173_RS02965	COG2813	Specifically methylates the guanine in position
FG173_RS02970	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FG173_RS02980	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FG173_RS02990	COG5487	UPF0391 membrane protein
FG173_RS02995	COG3237	CsbD-like
FG173_RS03000	COG4667	esterase of the alpha-beta hydrolase superfamily
FG173_RS03005	COG0084	hydrolase, TatD family'
FG173_RS03010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FG173_RS03015	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FG173_RS03020	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FG173_RS03025	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FG173_RS03030	COG0813	purine-nucleoside phosphorylase activity
FG173_RS03035	COG3726	membrane protein affecting hemolysin expression
FG173_RS03040	COG0560	Phosphoserine phosphatase
FG173_RS03060	COG0604	alcohol dehydrogenase
FG173_RS03070	COG2130	NADP-dependent
FG173_RS03085	COG0488	(ABC) transporter
FG173_RS03090	COG2885	chlorophyll binding
FG173_RS03095	COG2199	diguanylate cyclase activity
FG173_RS03105	COG0741	lytic transglycosylase activity
FG173_RS03110	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FG173_RS03115	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FG173_RS03120	COG0406	alpha-ribazole phosphatase activity
FG173_RS03125	COG3708	Transcriptional regulator
FG173_RS03125	COG2207	Transcriptional regulator
FG173_RS03130	COG3045	CreA protein
FG173_RS03140	COG0745	RESPONSE REGULATOR receiver
FG173_RS03170	COG3022	response to hydroperoxide
FG173_RS03175	COG1115	amino acid carrier protein
FG173_RS03180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FG173_RS03185	COG0521	Mo-molybdopterin cofactor biosynthetic process
FG173_RS03195	COG1584	GPR1 FUN34 yaaH family protein
FG173_RS03200	COG0443	Heat shock 70 kDa protein
FG173_RS03205	COG0484	heat shock protein binding
FG173_RS03210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FG173_RS03215	COG0583	DNA-binding transcription factor activity
FG173_RS03220	COG0268	Binds directly to 16S ribosomal RNA
FG173_RS03230	COG0196	riboflavin kinase activity
FG173_RS03235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FG173_RS03240	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FG173_RS03245	COG1047	Peptidyl-prolyl cis-trans
FG173_RS03250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FG173_RS03275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FG173_RS03280	COG0505	Belongs to the CarA family
FG173_RS03285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FG173_RS03305	COG2966	Psort location CytoplasmicMembrane, score
FG173_RS03315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FG173_RS03325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FG173_RS03330	COG2967	ApaG domain
FG173_RS03335	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FG173_RS03340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FG173_RS03350	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FG173_RS03360	COG0564	pseudouridine synthase activity
FG173_RS03365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FG173_RS03370	COG0417	DNA replication proofreading
FG173_RS03375	COG0586	Pfam SNARE associated Golgi protein
FG173_RS03380	COG0440	acetolactate synthase activity
FG173_RS03385	COG0028	Belongs to the TPP enzyme family
FG173_RS03400	COG1178	ABC-type Fe3 transport system permease component
FG173_RS03405	COG4143	(ABC) transporter
FG173_RS03420	COG2814	Major facilitator Superfamily
FG173_RS03425	COG0471	metal ion transport
FG173_RS03430	COG0066	3-isopropylmalate dehydratase activity
FG173_RS03435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FG173_RS03440	COG0473	3-isopropylmalate dehydrogenase activity
FG173_RS03445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FG173_RS03455	COG0583	DNA-binding transcription factor activity
FG173_RS03460	COG1022	Amp-dependent synthetase and ligase
FG173_RS03465	COG0028	Belongs to the TPP enzyme family
FG173_RS03485	COG2001	Belongs to the MraZ family
FG173_RS03490	COG0275	rRNA processing
FG173_RS03495	COG3116	cell division
FG173_RS03500	COG0768	penicillin binding
FG173_RS03505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FG173_RS03510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FG173_RS03515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FG173_RS03525	COG0772	Belongs to the SEDS family
FG173_RS03530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FG173_RS03535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FG173_RS03545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FG173_RS03550	COG0849	cell division
FG173_RS03555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FG173_RS03575	COG0653	protein targeting
FG173_RS03580	COG0494	nUDIX hydrolase
FG173_RS03585	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FG173_RS03590	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FG173_RS03600	COG0516	GMP reductase activity
FG173_RS03605	COG1459	type II secretion system
FG173_RS03615	COG4969	Belongs to the N-Me-Phe pilin family
FG173_RS03625	COG3023	N-Acetylmuramoyl-L-alanine amidase
FG173_RS03630	COG3725	Membrane protein required for beta-lactamase induction
FG173_RS03635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FG173_RS03645	COG0316	Belongs to the HesB IscA family
FG173_RS03655	COG2860	membrane
FG173_RS03665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FG173_RS03670	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FG173_RS03675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FG173_RS03685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FG173_RS03690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FG173_RS03695	COG3956	TIGRFAM MazG family protein
FG173_RS03700	COG0504	CTP synthase activity
FG173_RS03715	COG2986	histidine ammonia-lyase
FG173_RS03720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FG173_RS03725	COG2271	Major facilitator Superfamily
FG173_RS03730	COG0602	queuosine metabolic process
FG173_RS03735	COG0720	synthase
FG173_RS03740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FG173_RS03745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FG173_RS03750	COG0175	sulfate reduction
FG173_RS03755	COG2234	aminopeptidase activity
FG173_RS03760	COG1648	precorrin-2 dehydrogenase activity
FG173_RS03760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FG173_RS03770	COG2895	sulfate adenylyltransferase (ATP) activity
FG173_RS03790	COG0765	amino acid transport
FG173_RS03800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FG173_RS03805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FG173_RS03810	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FG173_RS03815	COG0585	pseudouridine synthase activity
FG173_RS03820	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FG173_RS03825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FG173_RS03830	COG4942	peptidase
FG173_RS03830	COG1388	LysM domain
FG173_RS03835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FG173_RS03850	COG0667	Aldo Keto reductase
FG173_RS03865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FG173_RS03870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FG173_RS03875	COG2723	6-phospho-beta-galactosidase activity
FG173_RS03880	COG2169	Transcriptional regulator
FG173_RS03880	COG1917	Cupin 2, conserved barrel domain protein
FG173_RS03905	COG2137	regulation of response to DNA damage stimulus
FG173_RS03910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FG173_RS03915	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FG173_RS03940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FG173_RS03945	COG1238	metal cluster binding
FG173_RS03950	COG2918	glutathione biosynthetic process
FG173_RS03960	COG4536	flavin adenine dinucleotide binding
FG173_RS03965	COG4137	Cytochrome C assembly protein
FG173_RS03970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FG173_RS03975	COG0228	four-way junction DNA binding
FG173_RS03980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FG173_RS03990	COG0335	large ribosomal subunit rRNA binding
FG173_RS04110	COG3137	Salt-induced outer membrane protein
FG173_RS04115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FG173_RS04125	COG1605	Chorismate mutase
FG173_RS04125	COG0077	Prephenate dehydratase
FG173_RS04135	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FG173_RS04140	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FG173_RS04150	COG0564	pseudouridine synthase activity
FG173_RS04160	COG0542	response to heat
FG173_RS04190	COG0656	L-ascorbic acid biosynthetic process
FG173_RS04195	COG0583	DNA-binding transcription factor activity
FG173_RS04210	COG1388	LysM domain
FG173_RS04210	COG0741	lytic transglycosylase activity
FG173_RS04215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FG173_RS04220	COG2226	methyltransferase
FG173_RS04225	COG0328	RNA-DNA hybrid ribonuclease activity
FG173_RS04230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FG173_RS04255	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FG173_RS04270	COG0436	Aminotransferase
FG173_RS04275	COG0235	Class ii aldolase
FG173_RS04280	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FG173_RS04285	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FG173_RS04290	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FG173_RS04295	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FG173_RS04300	COG0831	urea catabolic process
FG173_RS04305	COG0832	Belongs to the urease beta subunit family
FG173_RS04310	COG0804	urea catabolic process
FG173_RS04315	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FG173_RS04320	COG0830	nickel cation binding
FG173_RS04325	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FG173_RS04330	COG0829	nickel cation binding
FG173_RS04340	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FG173_RS04350	COG1960	acyl-CoA dehydrogenase activity
FG173_RS04355	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FG173_RS04360	COG0121	glutamine amidotransferase
FG173_RS04365	COG3034	peptidoglycan biosynthetic process
FG173_RS04370	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FG173_RS04375	COG1805	sodium ion transport
FG173_RS04380	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FG173_RS04385	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FG173_RS04390	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FG173_RS04395	COG2871	sodium ion transport
FG173_RS04400	COG1477	protein flavinylation
FG173_RS04405	COG2991	Protein conserved in bacteria
FG173_RS04420	COG0584	glycerophosphoryl diester phosphodiesterase
FG173_RS04425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FG173_RS04430	COG2195	Cleaves the N-terminal amino acid of tripeptides
FG173_RS04435	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FG173_RS04440	COG1073	alpha beta
FG173_RS04465	COG0582	viral genome integration into host DNA
FG173_RS04520	COG3188	usher protein
FG173_RS04525	COG3121	Chaperone
FG173_RS04595	COG2314	TM2 domain
FG173_RS04625	COG3038	cytochrome b561
FG173_RS04630	COG0747	negative chemotaxis
FG173_RS04635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FG173_RS04640	COG1733	regulation of RNA biosynthetic process
FG173_RS04645	COG2249	NAD(P)H dehydrogenase (quinone) activity
FG173_RS04660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FG173_RS04670	COG2207	Transcriptional regulator
FG173_RS04675	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS04685	COG2169	Transcriptional regulator
FG173_RS04685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FG173_RS04705	COG3961	Belongs to the TPP enzyme family
FG173_RS04740	COG1349	DNA-binding transcription factor activity
FG173_RS04760	COG1335	isochorismatase
FG173_RS04770	COG3011	Protein conserved in bacteria
FG173_RS04780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FG173_RS04785	COG3416	Protein conserved in bacteria
FG173_RS04795	COG2226	methyltransferase
FG173_RS04850	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FG173_RS04870	COG1595	DNA-templated transcription, initiation
FG173_RS04920	COG4126	flavin adenine dinucleotide binding
FG173_RS04925	COG3123	guanosine phosphorylase activity
FG173_RS04930	COG2974	May be involved in recombination
FG173_RS04935	COG1940	carbohydrate kinase activity
FG173_RS04960	COG0420	3'-5' exonuclease activity
FG173_RS04965	COG0745	RESPONSE REGULATOR receiver
FG173_RS04970	COG5002	protein histidine kinase activity
FG173_RS04990	COG3093	addiction module antidote protein HigA
FG173_RS05005	COG0668	transmembrane transport
FG173_RS05010	COG0366	Alpha amylase catalytic
FG173_RS05020	COG0450	alkyl hydroperoxide reductase
FG173_RS05030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FG173_RS05035	COG0343	queuine tRNA-ribosyltransferase activity
FG173_RS05040	COG1862	Preprotein translocase
FG173_RS05050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FG173_RS05055	COG4238	major outer membrane lipoprotein
FG173_RS05060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FG173_RS05065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FG173_RS05065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FG173_RS05070	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FG173_RS05075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FG173_RS05080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FG173_RS05085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FG173_RS05090	COG0667	Aldo Keto reductase
FG173_RS05095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FG173_RS05100	COG0142	geranyltranstransferase activity
FG173_RS05105	COG1722	exodeoxyribonuclease VII activity
FG173_RS05110	COG0301	tRNA thio-modification
FG173_RS05110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FG173_RS05115	COG0693	protein deglycase activity
FG173_RS05120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FG173_RS05125	COG1666	GTP binding
FG173_RS05130	COG2814	Major facilitator Superfamily
FG173_RS05140	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FG173_RS05145	COG1845	cytochrome c oxidase, subunit III
FG173_RS05150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FG173_RS05155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FG173_RS05160	COG2223	nitrite transmembrane transporter activity
FG173_RS05165	COG3056	Lipoprotein
FG173_RS05170	COG0271	Belongs to the BolA IbaG family
FG173_RS05175	COG0544	peptidyl-prolyl cis-trans isomerase activity
FG173_RS05185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FG173_RS05190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FG173_RS05200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FG173_RS05205	COG1555	photosystem II stabilization
FG173_RS05210	COG0824	Thioesterase
FG173_RS05215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FG173_RS05220	COG4533	DNA binding
FG173_RS05225	COG0561	phosphatase activity
FG173_RS05235	COG1522	sequence-specific DNA binding
FG173_RS05240	COG1132	(ABC) transporter
FG173_RS05245	COG1132	(ABC) transporter
FG173_RS05250	COG0347	Belongs to the P(II) protein family
FG173_RS05255	COG0004	ammonium transporteR
FG173_RS05260	COG1946	Acyl-CoA thioesterase
FG173_RS05265	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FG173_RS05305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FG173_RS05360	COG3397	chitin binding
FG173_RS05385	COG1121	(ABC) transporter
FG173_RS05390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FG173_RS05395	COG0803	Belongs to the bacterial solute-binding protein 9 family
FG173_RS05400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FG173_RS05405	COG0254	rRNA binding
FG173_RS05410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FG173_RS05415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FG173_RS05425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FG173_RS05430	COG1196	nuclear chromosome segregation
FG173_RS05430	COG3264	Mechanosensitive ion channel
FG173_RS05445	COG2832	Protein of unknown function (DUF454)
FG173_RS05450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FG173_RS05465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FG173_RS05470	COG0326	Molecular chaperone. Has ATPase activity
FG173_RS05475	COG0563	adenylate kinase activity
FG173_RS05480	COG3835	regulator
FG173_RS05485	COG2610	gluconate transmembrane transporter activity
FG173_RS05490	COG1929	Belongs to the glycerate kinase type-1 family
FG173_RS05495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FG173_RS05500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FG173_RS05505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FG173_RS05505	COG4651	solute:proton antiporter activity
FG173_RS05510	COG2223	nitrite transmembrane transporter activity
FG173_RS05515	COG0737	Belongs to the 5'-nucleotidase family
FG173_RS05520	COG2027	D-alanyl-D-alanine carboxypeptidase
FG173_RS05530	COG3735	TraB family
FG173_RS05535	COG2217	Heavy metal translocating P-type atpase
FG173_RS05540	COG0789	Transcriptional regulator
FG173_RS05545	COG1585	Membrane protein implicated in regulation of membrane protease activity
FG173_RS05550	COG0330	HflC and HflK could
FG173_RS05570	COG3960	tartronate-semialdehyde synthase activity
FG173_RS05575	COG3622	Belongs to the hyi family
FG173_RS05580	COG2084	Dehydrogenase
FG173_RS05585	COG2271	Major facilitator Superfamily
FG173_RS05590	COG1929	Belongs to the glycerate kinase type-1 family
FG173_RS05595	COG3257	ureidoglycine aminohydrolase activity
FG173_RS05605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FG173_RS05615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FG173_RS05620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FG173_RS05630	COG0549	Belongs to the carbamate kinase family
FG173_RS05635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FG173_RS05640	COG3118	belongs to the thioredoxin family
FG173_RS05645	COG0300	oxidoreductase activity
FG173_RS05650	COG2755	lipolytic protein G-D-S-L family
FG173_RS05655	COG4181	ATPase activity
FG173_RS05660	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FG173_RS05665	COG2814	Major facilitator Superfamily
FG173_RS05670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FG173_RS05675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FG173_RS05680	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FG173_RS05685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FG173_RS05690	COG0215	cysteine-tRNA ligase activity
FG173_RS05695	COG2501	S4 domain
FG173_RS05700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FG173_RS05715	COG0582	viral genome integration into host DNA
FG173_RS05740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FG173_RS05755	COG0025	NhaP-type Na H and K H
FG173_RS05780	COG0745	RESPONSE REGULATOR receiver
FG173_RS05795	COG3188	usher protein
FG173_RS05800	COG3121	Chaperone
FG173_RS05820	COG3539	Fimbrial protein
FG173_RS05880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FG173_RS05890	COG1609	Transcriptional regulator
FG173_RS05915	COG0259	pyridoxamine-phosphate oxidase activity
FG173_RS05945	COG0859	PFAM glycosyl transferase family 9
FG173_RS05960	COG2003	Belongs to the UPF0758 family
FG173_RS05995	COG2199	diguanylate cyclase activity
FG173_RS06000	COG1278	Cold shock
FG173_RS06010	COG1126	abc transporter atp-binding protein
FG173_RS06015	COG0765	amino acid transport
FG173_RS06025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FG173_RS06030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FG173_RS06045	COG2814	Major facilitator Superfamily
FG173_RS06050	COG1309	transcriptional regulator
FG173_RS06055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FG173_RS06065	COG3706	GGDEF domain
FG173_RS06075	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FG173_RS06080	COG0321	lipoyl(octanoyl) transferase activity
FG173_RS06090	COG1686	Belongs to the peptidase S11 family
FG173_RS06100	COG0772	Belongs to the SEDS family
FG173_RS06105	COG0768	penicillin binding
FG173_RS06110	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FG173_RS06115	COG0799	negative regulation of ribosome biogenesis
FG173_RS06120	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FG173_RS06125	COG1466	dna polymerase III delta subunit
FG173_RS06130	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FG173_RS06135	COG0495	leucyl-tRNA aminoacylation
FG173_RS06140	COG2888	peptidyl-tyrosine sulfation
FG173_RS06160	COG1126	abc transporter atp-binding protein
FG173_RS06165	COG0765	amino acid transport
FG173_RS06170	COG0765	amino acid transport
FG173_RS06180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FG173_RS06190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FG173_RS06195	COG1702	phosphate starvation-inducible protein PhoH
FG173_RS06200	COG2824	Alkylphosphonate utilization operon protein PhnA
FG173_RS06205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FG173_RS06210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FG173_RS06245	COG0367	asparagine synthase
FG173_RS06250	COG3469	chitinase activity
FG173_RS06255	COG0647	UMP catabolic process
FG173_RS06260	COG1940	carbohydrate kinase activity
FG173_RS06260	COG1846	Transcriptional regulator
FG173_RS06265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FG173_RS06270	COG0363	glucosamine-6-phosphate deaminase activity
FG173_RS06275	COG2190	(PTS) system
FG173_RS06275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FG173_RS06275	COG1263	PTS System
FG173_RS06280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FG173_RS06300	COG0735	belongs to the Fur family
FG173_RS06315	COG0596	Alpha beta hydrolase
FG173_RS06320	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FG173_RS06325	COG0033	Phosphoglucomutase
FG173_RS06340	COG0745	RESPONSE REGULATOR receiver
FG173_RS06345	COG2205	protein histidine kinase activity
FG173_RS06350	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FG173_RS06355	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FG173_RS06360	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FG173_RS06375	COG3272	Protein of unknown function (DUF1722)
FG173_RS06385	COG5212	phosphodiesterase
FG173_RS06390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FG173_RS06395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FG173_RS06405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FG173_RS06440	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FG173_RS06450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FG173_RS06455	COG0567	Dehydrogenase, E1 component
FG173_RS06460	COG0508	dehydrogenase complex catalyzes the overall conversion of
FG173_RS06465	COG0045	succinate-CoA ligase (ADP-forming) activity
FG173_RS06470	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FG173_RS06475	COG0737	Belongs to the 5'-nucleotidase family
FG173_RS06480	COG1271	oxidase subunit
FG173_RS06485	COG1294	oxidase, subunit
FG173_RS06490	COG4890	Cyd operon protein YbgT
FG173_RS06495	COG3790	cyd operon protein YbgE
FG173_RS06500	COG0824	Thioesterase
FG173_RS06505	COG0811	peptide transport
FG173_RS06510	COG0848	biopolymer transport protein
FG173_RS06515	COG3064	Membrane
FG173_RS06520	COG0823	Involved in the tonB-independent uptake of proteins
FG173_RS06525	COG2885	chlorophyll binding
FG173_RS06530	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FG173_RS06580	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FG173_RS06590	COG1230	cation diffusion facilitator family transporter
FG173_RS06595	COG2205	protein histidine kinase activity
FG173_RS06595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FG173_RS06605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FG173_RS06620	COG0588	phosphoglycerate mutase activity
FG173_RS06630	COG2017	converts alpha-aldose to the beta-anomer
FG173_RS06635	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FG173_RS06640	COG1085	galactose-1-phosphate uridylyltransferase
FG173_RS06655	COG1119	ATPase activity
FG173_RS06660	COG2005	Transcriptional regulator
FG173_RS06660	COG3585	molybdate ion transport
FG173_RS06665	COG4774	siderophore transport
FG173_RS06675	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FG173_RS06680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS06685	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FG173_RS06695	COG0725	ABC transporter, periplasmic molybdate-binding protein
FG173_RS06700	COG4149	molybdate abc transporter
FG173_RS06710	COG0561	phosphatase activity
FG173_RS06715	COG2706	6-phosphogluconolactonase activity
FG173_RS06720	COG1881	PFAM PEBP family protein
FG173_RS06775	COG0556	nucleotide-excision repair
FG173_RS06780	COG4628	conserved protein (DUF2132)
FG173_RS06785	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FG173_RS06790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FG173_RS06795	COG0521	Mo-molybdopterin cofactor biosynthetic process
FG173_RS06800	COG0315	cyclic pyranopterin monophosphate synthase activity
FG173_RS06805	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FG173_RS06810	COG0314	molybdopterin synthase activity
FG173_RS06815	COG0670	Belongs to the BI1 family
FG173_RS06820	COG0842	Transport permease protein
FG173_RS06825	COG0842	Transport permease protein
FG173_RS06830	COG1131	(ABC) transporter
FG173_RS06840	COG1309	transcriptional regulator
FG173_RS06845	COG0513	Belongs to the DEAD box helicase family
FG173_RS06855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FG173_RS06865	COG3842	ATPase activity
FG173_RS06875	COG1840	ABC-type Fe3 transport system, periplasmic component
FG173_RS06880	COG2271	Major facilitator Superfamily
FG173_RS06895	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FG173_RS06900	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS06910	COG0583	DNA-binding transcription factor activity
FG173_RS06930	COG0583	DNA-binding transcription factor activity
FG173_RS06935	COG0586	Pfam SNARE associated Golgi protein
FG173_RS06945	COG4977	sequence-specific DNA binding
FG173_RS06950	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FG173_RS06985	COG2354	Protein conserved in bacteria
FG173_RS06995	COG1464	Belongs to the NlpA lipoprotein family
FG173_RS07005	COG0456	acetyltransferase
FG173_RS07025	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FG173_RS07035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS07045	COG0840	transmembrane signaling receptor activity
FG173_RS07050	COG0277	FAD linked oxidase domain protein
FG173_RS07065	COG1181	Belongs to the D-alanine--D-alanine ligase family
FG173_RS07075	COG0436	Aminotransferase
FG173_RS07085	COG1472	Belongs to the glycosyl hydrolase 3 family
FG173_RS07105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FG173_RS07110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS07115	COG1120	ATPase activity
FG173_RS07130	COG2134	cdp-diacylglycerol pyrophosphatase
FG173_RS07160	COG1192	Involved in chromosome partitioning
FG173_RS07170	COG0583	DNA-binding transcription factor activity
FG173_RS07180	COG1070	Carbohydrate kinase
FG173_RS07185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FG173_RS07255	COG1309	transcriptional regulator
FG173_RS07260	COG1464	Belongs to the NlpA lipoprotein family
FG173_RS07265	COG2011	ABC-type metal ion transport system permease component
FG173_RS07270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FG173_RS07275	COG0519	Catalyzes the synthesis of GMP from XMP
FG173_RS07295	COG2084	Dehydrogenase
FG173_RS07310	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FG173_RS07325	COG4807	Protein conserved in bacteria
FG173_RS07345	COG1802	Transcriptional regulator
FG173_RS07365	COG0411	ABC transporter
FG173_RS07415	COG0583	DNA-binding transcription factor activity
FG173_RS07420	COG2897	thiosulfate sulfurtransferase activity
FG173_RS07425	COG0494	nUDIX hydrolase
FG173_RS07430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FG173_RS07440	COG0625	glutathione transferase activity
FG173_RS07450	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FG173_RS07460	COG1335	isochorismatase
FG173_RS07465	COG0583	DNA-binding transcription factor activity
FG173_RS07485	COG1732	Glycine betaine
FG173_RS07490	COG1174	glycine betaine transport
FG173_RS07495	COG1125	glycine betaine transport
FG173_RS07500	COG1174	glycine betaine transport
FG173_RS07515	COG0583	DNA-binding transcription factor activity
FG173_RS07520	COG0697	spore germination
FG173_RS07565	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FG173_RS07580	COG0625	glutathione transferase activity
FG173_RS07585	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FG173_RS07590	COG1942	4-Oxalocrotonate Tautomerase
FG173_RS07600	COG1522	sequence-specific DNA binding
FG173_RS07625	COG2079	MmgE PrpD family protein
FG173_RS07630	COG1280	lysine exporter protein (LysE YggA)
FG173_RS07650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FG173_RS07680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FG173_RS07685	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FG173_RS07695	COG1309	transcriptional regulator
FG173_RS07700	COG0456	acetyltransferase
FG173_RS07700	COG1214	PFAM Peptidase M22, glycoprotease
FG173_RS07715	COG1126	abc transporter atp-binding protein
FG173_RS07720	COG0765	amino acid transport
FG173_RS07725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FG173_RS07730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FG173_RS07745	COG2731	YhcH YjgK YiaL family protein
FG173_RS07755	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FG173_RS07760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FG173_RS07775	COG2610	gluconate transmembrane transporter activity
FG173_RS07780	COG3622	Belongs to the hyi family
FG173_RS07785	COG0235	Class ii aldolase
FG173_RS07790	COG3395	kinase activity
FG173_RS07795	COG2084	Dehydrogenase
FG173_RS07800	COG1349	DNA-binding transcription factor activity
FG173_RS07810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FG173_RS07815	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FG173_RS07855	COG3188	usher protein
FG173_RS07870	COG5002	protein histidine kinase activity
FG173_RS07875	COG0745	RESPONSE REGULATOR receiver
FG173_RS07880	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FG173_RS07885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FG173_RS07900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FG173_RS07905	COG1309	transcriptional regulator
FG173_RS07910	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS07915	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FG173_RS07920	COG0069	glutamate synthase activity
FG173_RS07930	COG2200	EAL domain
FG173_RS07935	COG3539	Fimbrial protein
FG173_RS07955	COG2207	Transcriptional regulator
FG173_RS07955	COG3708	Transcriptional regulator
FG173_RS07960	COG0579	oxidoreductase
FG173_RS07970	COG0625	glutathione transferase activity
FG173_RS07975	COG0640	Transcriptional regulator
FG173_RS07995	COG0583	DNA-binding transcription factor activity
FG173_RS08010	COG3811	Belongs to the UPF0386 family
FG173_RS08015	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FG173_RS08025	COG0583	DNA-binding transcription factor activity
FG173_RS08045	COG0488	(ABC) transporter
FG173_RS08075	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FG173_RS08075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FG173_RS08100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FG173_RS08105	COG0303	'Molybdopterin
FG173_RS08120	COG4172	Belongs to the ABC transporter superfamily
FG173_RS08125	COG0747	negative chemotaxis
FG173_RS08130	COG0601	transmembrane transport
FG173_RS08135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FG173_RS08160	COG0583	DNA-binding transcription factor activity
FG173_RS08165	COG0477	Major facilitator Superfamily
FG173_RS08170	COG0302	gtp cyclohydrolase
FG173_RS08175	COG2311	Membrane
FG173_RS08180	COG1609	Transcriptional regulator
FG173_RS08200	COG2949	membrane
FG173_RS08205	COG0281	malic enzyme
FG173_RS08210	COG0295	cytidine deaminase activity
FG173_RS08215	COG1346	cytolysis
FG173_RS08220	COG1380	Effector of murein hydrolase LrgA
FG173_RS08225	COG2814	Major facilitator Superfamily
FG173_RS08235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FG173_RS08235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FG173_RS08240	COG0489	protein tyrosine kinase activity
FG173_RS08250	COG0572	uridine kinase
FG173_RS08255	COG0717	Belongs to the dCTP deaminase family
FG173_RS08260	COG2982	Protein involved in outer membrane biogenesis
FG173_RS08270	COG1253	flavin adenine dinucleotide binding
FG173_RS08275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FG173_RS08280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FG173_RS08300	COG1083	cytidylyl-transferase
FG173_RS08305	COG2089	acid synthase
FG173_RS08310	COG2244	polysaccharide biosynthetic process
FG173_RS08380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FG173_RS08410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FG173_RS08435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FG173_RS08440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FG173_RS08440	COG0140	phosphoribosyl-ATP diphosphatase activity
FG173_RS08445	COG0107	imidazoleglycerol-phosphate synthase activity
FG173_RS08450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FG173_RS08465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FG173_RS08470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FG173_RS08475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FG173_RS08485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FG173_RS08490	COG0583	DNA-binding transcription factor activity
FG173_RS08495	COG2814	Major facilitator Superfamily
FG173_RS08515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FG173_RS08520	COG3153	acetyltransferase
FG173_RS08520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FG173_RS08525	COG0598	Magnesium transport protein CorA
FG173_RS08535	COG2133	pyrroloquinoline quinone binding
FG173_RS08540	COG0625	glutathione transferase activity
FG173_RS08555	COG0626	cystathionine gamma-synthase activity
FG173_RS08565	COG1686	Belongs to the peptidase S11 family
FG173_RS08590	COG3539	Fimbrial protein
FG173_RS08595	COG3188	usher protein
FG173_RS08600	COG3121	Chaperone
FG173_RS08620	COG0545	Peptidyl-prolyl cis-trans isomerase
FG173_RS08625	COG2197	response regulator
FG173_RS08630	COG1760	l-serine dehydratase
FG173_RS08635	COG0814	amino acid
FG173_RS08640	COG1349	DNA-binding transcription factor activity
FG173_RS08645	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FG173_RS08655	COG0671	phosphoesterase, PA-phosphatase related
FG173_RS08670	COG4574	serine-type endopeptidase inhibitor activity
FG173_RS08680	COG3395	kinase activity
FG173_RS08715	COG2985	domain, Protein
FG173_RS08715	COG0569	domain protein
FG173_RS08735	COG0189	ligase activity
FG173_RS08745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FG173_RS08750	COG3842	ATPase activity
FG173_RS08755	COG1176	ABC-type spermidine putrescine transport system, permease component I
FG173_RS08760	COG1177	transmembrane transport
FG173_RS08770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FG173_RS08775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FG173_RS08780	COG4160	amino acid transport
FG173_RS08785	COG4215	(ABC) transporter
FG173_RS08790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FG173_RS08795	COG1126	abc transporter atp-binding protein
FG173_RS08805	COG0393	Putative heavy-metal-binding
FG173_RS08815	COG3023	N-Acetylmuramoyl-L-alanine amidase
FG173_RS08820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FG173_RS08825	COG0702	epimerase
FG173_RS08835	COG1737	Transcriptional regulator
FG173_RS08840	COG1263	PTS System
FG173_RS08840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FG173_RS08840	COG2190	(PTS) system
FG173_RS08845	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FG173_RS08850	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FG173_RS08855	COG0028	Belongs to the TPP enzyme family
FG173_RS08860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FG173_RS08870	COG2431	L-lysine efflux transmembrane transporter activity
FG173_RS08875	COG3593	DNA synthesis involved in DNA repair
FG173_RS08880	COG2990	Protein conserved in bacteria
FG173_RS08885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FG173_RS08895	COG1278	Cold shock
FG173_RS08900	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FG173_RS08905	COG0542	response to heat
FG173_RS08910	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FG173_RS08915	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FG173_RS08920	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FG173_RS08930	COG0492	ferredoxin-NADP+ reductase activity
FG173_RS08940	COG1674	ftsk spoiiie
FG173_RS08940	COG3107	peptidoglycan biosynthetic process
FG173_RS08945	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FG173_RS08950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FG173_RS08955	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FG173_RS08965	COG2814	Major facilitator Superfamily
FG173_RS08970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FG173_RS08975	COG1882	Formate acetyltransferase
FG173_RS08980	COG2116	formate transmembrane transporter activity
FG173_RS08985	COG1944	ATP diphosphatase activity
FG173_RS08995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FG173_RS09000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FG173_RS09005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FG173_RS09010	COG0539	negative regulation of cytoplasmic translation
FG173_RS09020	COG0658	competence protein
FG173_RS09020	COG2333	competence protein COMEC
FG173_RS09025	COG1132	(ABC) transporter
FG173_RS09030	COG1663	tetraacyldisaccharide 4'-kinase activity
FG173_RS09035	COG5383	Protein conserved in bacteria
FG173_RS09045	COG1278	Cold shock
FG173_RS09050	COG3214	Protein conserved in bacteria
FG173_RS09055	COG2835	tetraacyldisaccharide 4'-kinase activity
FG173_RS09060	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FG173_RS09065	COG3173	Aminoglycoside phosphotransferase
FG173_RS09070	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FG173_RS09075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FG173_RS09080	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FG173_RS09090	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FG173_RS09095	COG2989	Protein conserved in bacteria
FG173_RS09100	COG3108	Peptidase M15
FG173_RS09105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FG173_RS09125	COG0017	Asparaginyl-tRNA synthetase
FG173_RS09130	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FG173_RS09135	COG3706	GGDEF domain
FG173_RS09140	COG0308	aminopeptidase N
FG173_RS09150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FG173_RS09155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FG173_RS09165	COG0431	NADPH-dependent FMN reductase
FG173_RS09170	COG0167	dihydroorotate dehydrogenase activity
FG173_RS09180	COG3217	Mosc domain protein beta barrel domain protein
FG173_RS09180	COG0633	Ferredoxin
FG173_RS09185	COG0116	Belongs to the methyltransferase superfamily
FG173_RS09185	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FG173_RS09190	COG0488	(ABC) transporter
FG173_RS09195	COG2995	paraquat-inducible protein a
FG173_RS09200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FG173_RS09200	COG3008	intermembrane lipid transfer
FG173_RS09205	COG3009	Protein conserved in bacteria
FG173_RS09210	COG3130	regulation of translation
FG173_RS09215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FG173_RS09225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FG173_RS09230	COG1067	ATP-dependent peptidase activity
FG173_RS09250	COG3070	regulator of competence-specific genes
FG173_RS09255	COG1289	transmembrane transporter activity
FG173_RS09260	COG3304	Inner membrane component domain
FG173_RS09265	COG0210	DNA helicase
FG173_RS09270	COG1803	Methylglyoxal synthase
FG173_RS09280	COG1832	CoA-binding protein
FG173_RS09285	COG3785	DNA binding
FG173_RS09290	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FG173_RS09300	COG3594	Acyltransferase
FG173_RS09305	COG1254	Belongs to the acylphosphatase family
FG173_RS09310	COG2920	part of a sulfur-relay system
FG173_RS09315	COG0670	Belongs to the BI1 family
FG173_RS09335	COG3121	Chaperone
FG173_RS09340	COG3188	usher protein
FG173_RS09360	COG0789	Transcriptional regulator
FG173_RS09365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FG173_RS09370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FG173_RS09380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FG173_RS09390	COG0655	NAD(P)H dehydrogenase (quinone) activity
FG173_RS09410	COG1113	amino acid transport
FG173_RS09420	COG0586	Pfam SNARE associated Golgi protein
FG173_RS09425	COG2271	Major facilitator Superfamily
FG173_RS09445	COG2814	Major facilitator Superfamily
FG173_RS09450	COG2197	response regulator
FG173_RS09455	COG0589	response to stress
FG173_RS09470	COG0531	amino acid
FG173_RS09480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FG173_RS09525	COG3136	membrane protein required for alginate biosynthesis
FG173_RS09535	COG2197	response regulator
FG173_RS09540	COG0322	excinuclease ABC activity
FG173_RS09575	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FG173_RS09615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FG173_RS09620	COG0322	excinuclease ABC activity
FG173_RS09655	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FG173_RS09660	COG2943	transferase activity, transferring hexosyl groups
FG173_RS09665	COG5645	(Lipo)protein
FG173_RS09680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FG173_RS09690	COG0640	Transcriptional regulator
FG173_RS09705	COG0346	lactoylglutathione lyase activity
FG173_RS09715	COG2814	Major facilitator Superfamily
FG173_RS09725	COG1560	Kdo2-lipid A biosynthetic process
FG173_RS09735	COG1054	Belongs to the UPF0176 family
FG173_RS09740	COG2353	YceI-like domain
FG173_RS09745	COG3038	cytochrome b561
FG173_RS09750	COG0628	permease
FG173_RS09800	COG0418	dihydroorotase activity
FG173_RS09815	COG0564	pseudouridine synthase activity
FG173_RS09825	COG1399	metal-binding, possibly nucleic acid-binding protein
FG173_RS09830	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FG173_RS09835	COG0416	fatty acid biosynthetic process
FG173_RS09840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FG173_RS09845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FG173_RS09855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FG173_RS09860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FG173_RS09865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FG173_RS09870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FG173_RS09875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FG173_RS09880	COG0470	DNA polymerase III
FG173_RS09885	COG0084	hydrolase, TatD family'
FG173_RS09890	COG1263	PTS System
FG173_RS09890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FG173_RS09900	COG1321	iron dependent repressor
FG173_RS09905	COG1914	H( )-stimulated, divalent metal cation uptake system
FG173_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS09915	COG1733	regulation of RNA biosynthetic process
FG173_RS09920	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FG173_RS09925	COG0537	adenosine 5'-monophosphoramidase activity
FG173_RS09930	COG5633	Lipoprotein
FG173_RS09935	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FG173_RS09950	COG3150	esterase
FG173_RS09955	COG1252	NADH dehydrogenase
FG173_RS09960	COG3134	Outer membrane lipoprotein
FG173_RS09975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FG173_RS09980	COG3708	Transcriptional regulator
FG173_RS09980	COG2207	Transcriptional regulator
FG173_RS10010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FG173_RS10015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FG173_RS10020	COG3381	protein complex oligomerization
FG173_RS10025	COG2979	Protein of unknown function (DUF533)
FG173_RS10030	COG1770	oligopeptidase
FG173_RS10035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FG173_RS10060	COG1528	Iron-storage protein
FG173_RS10065	COG2372	response to copper ion
FG173_RS10070	COG1276	copper resistance
FG173_RS10080	COG0582	viral genome integration into host DNA
FG173_RS10205	COG2801	Transposase and inactivated derivatives
FG173_RS10235	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FG173_RS10255	COG4565	transcriptional regulatory protein
FG173_RS10260	COG3290	protein histidine kinase activity
FG173_RS10275	COG1129	ABC transporter
FG173_RS10280	COG1172	Belongs to the binding-protein-dependent transport system permease family
FG173_RS10295	COG0579	oxidoreductase
FG173_RS10310	COG2358	TRAP transporter, solute receptor (TAXI family
FG173_RS10315	COG1464	Belongs to the NlpA lipoprotein family
FG173_RS10325	COG0589	response to stress
FG173_RS10330	COG3408	Glycogen debranching enzyme
FG173_RS10330	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FG173_RS10340	COG1609	Transcriptional regulator
FG173_RS10345	COG3250	beta-galactosidase activity
FG173_RS10350	COG2731	YhcH YjgK YiaL family protein
FG173_RS10355	COG0531	amino acid
FG173_RS10360	COG0640	Transcriptional regulator
FG173_RS10370	COG0740	serine-type endopeptidase activity
FG173_RS10430	COG0012	GTP binding
FG173_RS10435	COG0659	secondary active sulfate transmembrane transporter activity
FG173_RS10440	COG0193	aminoacyl-tRNA hydrolase activity
FG173_RS10450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FG173_RS10455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FG173_RS10460	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FG173_RS10465	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FG173_RS10470	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FG173_RS10485	COG2912	Transglutaminase-like superfamily
FG173_RS10500	COG4702	Belongs to the UPF0303 family
FG173_RS10505	COG3706	GGDEF domain
FG173_RS10510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FG173_RS10525	COG4591	ABC-type transport system involved in lipoprotein release permease component
FG173_RS10535	COG4591	ABC-type transport system involved in lipoprotein release permease component
FG173_RS10560	COG1486	melibiose metabolic process
FG173_RS10565	COG1263	PTS System
FG173_RS10565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FG173_RS10570	COG1177	transmembrane transport
FG173_RS10590	COG2195	Cleaves the N-terminal amino acid of tripeptides
FG173_RS10595	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FG173_RS10600	COG2850	peptidyl-arginine hydroxylation
FG173_RS10610	COG0745	RESPONSE REGULATOR receiver
FG173_RS10620	COG2188	Transcriptional regulator
FG173_RS10635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FG173_RS10645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FG173_RS10650	COG2915	High frequency lysogenization protein hflD homolog
FG173_RS10660	COG0482	sulfurtransferase activity
FG173_RS10675	COG1187	pseudouridine synthase activity
FG173_RS10680	COG0538	isocitrate dehydrogenase activity
FG173_RS10700	COG3064	Membrane
FG173_RS10760	COG1278	Cold shock
FG173_RS10770	COG1335	isochorismatase
FG173_RS10775	COG0589	response to stress
FG173_RS10780	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS10785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FG173_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS10795	COG1917	Cupin 2, conserved barrel domain protein
FG173_RS10795	COG1396	sequence-specific DNA binding
FG173_RS10800	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FG173_RS10805	COG0174	glutamine synthetase
FG173_RS10815	COG0531	amino acid
FG173_RS10830	COG4977	sequence-specific DNA binding
FG173_RS10855	COG1605	Chorismate mutase
FG173_RS10870	COG1228	amidohydrolase
FG173_RS10880	COG0402	S-adenosylhomocysteine deaminase activity
FG173_RS10900	COG2211	Major facilitator Superfamily
FG173_RS10905	COG0477	Major facilitator Superfamily
FG173_RS10925	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FG173_RS10930	COG3493	citrate carrier protein
FG173_RS10940	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FG173_RS11005	COG3008	intermembrane lipid transfer
FG173_RS11010	COG2995	paraquat-inducible protein a
FG173_RS11015	COG1956	GAF domain-containing protein
FG173_RS11025	COG0793	Belongs to the peptidase S41A family
FG173_RS11045	COG1120	ATPase activity
FG173_RS11050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS11055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FG173_RS11060	COG0501	Belongs to the peptidase M48B family
FG173_RS11070	COG1414	Transcriptional regulator
FG173_RS11095	COG2188	Transcriptional regulator
FG173_RS11110	COG1823	symporter activity
FG173_RS11115	COG1988	membrane-bound metal-dependent
FG173_RS11120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FG173_RS11135	COG3001	Fructosamine kinase
FG173_RS11140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FG173_RS11145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FG173_RS11150	COG1121	(ABC) transporter
FG173_RS11155	COG0803	Belongs to the bacterial solute-binding protein 9 family
FG173_RS11185	COG0814	amino acid
FG173_RS11215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FG173_RS11225	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FG173_RS11230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FG173_RS11240	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FG173_RS11260	COG4139	cobalamin transport
FG173_RS11265	COG0386	Belongs to the glutathione peroxidase family
FG173_RS11275	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FG173_RS11280	COG1215	transferase activity, transferring glycosyl groups
FG173_RS11290	COG0726	polysaccharide deacetylase
FG173_RS11295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FG173_RS11300	COG2076	Multidrug Resistance protein
FG173_RS11305	COG2076	Multidrug Resistance protein
FG173_RS11310	COG0791	NLP P60 protein
FG173_RS11315	COG0095	Lipoate-protein ligase
FG173_RS11335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS11360	COG0386	Belongs to the glutathione peroxidase family
FG173_RS11370	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FG173_RS11380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FG173_RS11380	COG0574	Belongs to the PEP-utilizing enzyme family
FG173_RS11390	COG0628	permease
FG173_RS11395	COG0247	lactate metabolic process
FG173_RS11395	COG0277	FAD linked oxidase domain protein
FG173_RS11400	COG2050	protein possibly involved in aromatic compounds catabolism
FG173_RS11410	COG0316	Belongs to the HesB IscA family
FG173_RS11415	COG0719	Fe-S assembly protein
FG173_RS11420	COG0396	ATPase activity
FG173_RS11425	COG0719	Fe-S assembly protein
FG173_RS11430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FG173_RS11435	COG2166	iron-sulfur cluster assembly
FG173_RS11440	COG1388	LysM domain
FG173_RS11440	COG1376	ErfK ybiS ycfS ynhG family protein
FG173_RS11450	COG0469	pyruvate kinase activity
FG173_RS11480	COG0307	riboflavin synthase, alpha
FG173_RS11490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FG173_RS11495	COG2814	Major facilitator Superfamily
FG173_RS11500	COG0583	DNA-binding transcription factor activity
FG173_RS11505	COG1609	Transcriptional regulator
FG173_RS11525	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FG173_RS11535	COG0346	lactoylglutathione lyase activity
FG173_RS11540	COG1902	pentaerythritol trinitrate reductase activity
FG173_RS11545	COG1309	transcriptional regulator
FG173_RS11550	COG2194	sulfuric ester hydrolase activity
FG173_RS11560	COG0583	DNA-binding transcription factor activity
FG173_RS11565	COG3313	Fe-S protein
FG173_RS11570	COG4989	oxidoreductase activity
FG173_RS11575	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FG173_RS11585	COG1289	transmembrane transporter activity
FG173_RS11590	COG1566	PFAM secretion protein HlyD family protein
FG173_RS11600	COG1846	Transcriptional regulator
FG173_RS11605	COG3133	Outer membrane lipoprotein
FG173_RS11610	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FG173_RS11620	COG0259	pyridoxamine-phosphate oxidase activity
FG173_RS11625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FG173_RS11635	COG0625	glutathione transferase activity
FG173_RS11650	COG1418	mRNA catabolic process
FG173_RS11695	COG3135	benzoate transporter
FG173_RS11700	COG1396	sequence-specific DNA binding
FG173_RS11710	COG3104	oligopeptide transport
FG173_RS11715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FG173_RS11725	COG4659	FMN binding
FG173_RS11735	COG2207	Transcriptional regulator
FG173_RS11735	COG3708	Transcriptional regulator
FG173_RS11740	COG4656	Part of a membrane complex involved in electron transport
FG173_RS11745	COG2878	Part of a membrane complex involved in electron transport
FG173_RS11750	COG4657	Part of a membrane complex involved in electron transport
FG173_RS11760	COG0673	inositol 2-dehydrogenase activity
FG173_RS11765	COG0385	Bile acid
FG173_RS11775	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FG173_RS11780	COG1349	DNA-binding transcription factor activity
FG173_RS11795	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FG173_RS11800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FG173_RS11800	COG1263	PTS System
FG173_RS11805	COG1609	Transcriptional regulator
FG173_RS11820	COG0583	DNA-binding transcription factor activity
FG173_RS11830	COG5339	Protein conserved in bacteria
FG173_RS11845	COG0114	fumarate hydratase activity
FG173_RS11860	COG2378	regulation of single-species biofilm formation
FG173_RS11880	COG1649	PFAM Uncharacterised BCR, COG1649
FG173_RS11885	COG2814	Major facilitator Superfamily
FG173_RS11890	COG0583	DNA-binding transcription factor activity
FG173_RS11895	COG1940	carbohydrate kinase activity
FG173_RS11900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FG173_RS11910	COG0789	Transcriptional regulator
FG173_RS11940	COG0477	Major facilitator Superfamily
FG173_RS11955	COG1742	UPF0060 membrane protein
FG173_RS11960	COG4221	oxidoreductase activity
FG173_RS11970	COG4772	TonB-dependent receptor
FG173_RS11980	COG3712	iron ion homeostasis
FG173_RS11985	COG1595	DNA-templated transcription, initiation
FG173_RS11995	COG0402	S-adenosylhomocysteine deaminase activity
FG173_RS12010	COG0339	signal peptide processing
FG173_RS12015	COG2271	Major facilitator Superfamily
FG173_RS12020	COG1335	isochorismatase
FG173_RS12025	COG3473	Maleate cis-trans isomerase
FG173_RS12030	COG0596	Alpha beta hydrolase
FG173_RS12035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FG173_RS12040	COG2309	aminopeptidase activity
FG173_RS12045	COG1846	Transcriptional regulator
FG173_RS12050	COG2080	2 iron, 2 sulfur cluster binding
FG173_RS12065	COG0583	DNA-binding transcription factor activity
FG173_RS12150	COG4221	oxidoreductase activity
FG173_RS12155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FG173_RS12165	COG1280	lysine exporter protein (LysE YggA)
FG173_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS12190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FG173_RS12205	COG1073	alpha beta
FG173_RS12210	COG2140	Oxalate decarboxylase
FG173_RS12245	COG0596	Alpha beta hydrolase
FG173_RS12265	COG3209	COG3209 Rhs family protein
FG173_RS12305	COG2814	Major facilitator Superfamily
FG173_RS12325	COG0768	penicillin binding
FG173_RS12345	COG0840	transmembrane signaling receptor activity
FG173_RS12370	COG0583	DNA-binding transcription factor activity
FG173_RS12380	COG2814	Major facilitator Superfamily
FG173_RS12390	COG1349	DNA-binding transcription factor activity
FG173_RS12395	COG0673	inositol 2-dehydrogenase activity
FG173_RS12425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FG173_RS12430	COG2862	Uncharacterized protein family, UPF0114
FG173_RS12445	COG0446	pyridine nucleotide-disulphide oxidoreductase
FG173_RS12455	COG3453	Protein conserved in bacteria
FG173_RS12455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FG173_RS12460	COG1064	alcohol dehydrogenase
FG173_RS12475	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FG173_RS12515	COG2223	nitrite transmembrane transporter activity
FG173_RS12525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FG173_RS12540	COG3300	MHYT domain
FG173_RS12540	COG5001	Diguanylate cyclase
FG173_RS12560	COG1802	Transcriptional regulator
FG173_RS12570	COG2267	carboxylic ester hydrolase activity
FG173_RS12585	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS12590	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FG173_RS12630	COG0583	DNA-binding transcription factor activity
FG173_RS12635	COG0076	glutamate decarboxylase activity
FG173_RS12640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FG173_RS12655	COG0148	phosphopyruvate hydratase activity
FG173_RS12665	COG1227	inorganic diphosphatase activity
FG173_RS12670	COG5001	Diguanylate cyclase
FG173_RS12670	COG5002	protein histidine kinase activity
FG173_RS12670	COG3447	MASE1 domain protein
FG173_RS12690	COG0583	DNA-binding transcription factor activity
FG173_RS12715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FG173_RS12725	COG0583	DNA-binding transcription factor activity
FG173_RS12750	COG4221	oxidoreductase activity
FG173_RS12755	COG4221	oxidoreductase activity
FG173_RS12770	COG1082	Xylose isomerase domain protein TIM barrel
FG173_RS12775	COG0673	inositol 2-dehydrogenase activity
FG173_RS12810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FG173_RS12850	COG2249	NAD(P)H dehydrogenase (quinone) activity
FG173_RS12855	COG2249	NAD(P)H dehydrogenase (quinone) activity
FG173_RS12860	COG1733	regulation of RNA biosynthetic process
FG173_RS12865	COG0477	Major facilitator Superfamily
FG173_RS12885	COG4774	siderophore transport
FG173_RS12900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FG173_RS12905	COG0318	PFAM AMP-dependent synthetase and ligase
FG173_RS12910	COG0693	protein deglycase activity
FG173_RS12945	COG2957	Belongs to the agmatine deiminase family
FG173_RS12950	COG0583	DNA-binding transcription factor activity
FG173_RS12985	COG0778	Nitroreductase
FG173_RS12990	COG2010	Cytochrome c
FG173_RS12990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FG173_RS12995	COG2010	Cytochrome c
FG173_RS12995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FG173_RS13000	COG2080	2 iron, 2 sulfur cluster binding
FG173_RS13015	COG1737	Transcriptional regulator
FG173_RS13020	COG2723	6-phospho-beta-galactosidase activity
FG173_RS13040	COG5507	3-demethylubiquinone-9 3-methyltransferase
FG173_RS13045	COG2199	diguanylate cyclase activity
FG173_RS13075	COG0488	(ABC) transporter
FG173_RS13090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FG173_RS13105	COG2239	Acts as a magnesium transporter
FG173_RS13140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FG173_RS13195	COG3158	transport of potassium into the cell
FG173_RS13200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FG173_RS13205	COG1116	anion transmembrane transporter activity
FG173_RS13290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FG173_RS13310	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FG173_RS13360	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FG173_RS13385	COG1175	transmembrane transport
FG173_RS13390	COG0395	ABC-type sugar transport system, permease component
FG173_RS13395	COG3842	ATPase activity
FG173_RS13400	COG0673	inositol 2-dehydrogenase activity
FG173_RS13410	COG1349	DNA-binding transcription factor activity
FG173_RS13415	COG2222	sugar isomerase
FG173_RS13430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FG173_RS13440	COG0589	response to stress
FG173_RS13465	COG0531	amino acid
FG173_RS13490	COG0745	RESPONSE REGULATOR receiver
FG173_RS13495	COG2205	protein histidine kinase activity
FG173_RS13500	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FG173_RS13520	COG2207	Transcriptional regulator
FG173_RS13525	COG2814	Major facilitator Superfamily
FG173_RS13535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FG173_RS13540	COG3784	Protein of unknown function (DUF1318)
FG173_RS13555	COG0583	DNA-binding transcription factor activity
FG173_RS13565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FG173_RS13570	COG3187	Heat shock protein
FG173_RS13575	COG3042	response to heat
FG173_RS13585	COG0674	pyruvate-flavodoxin oxidoreductase activity
FG173_RS13585	COG1013	pyruvate-flavodoxin oxidoreductase activity
FG173_RS13585	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FG173_RS13585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FG173_RS13595	COG0037	tRNA processing
FG173_RS13620	COG4166	transmembrane transport
FG173_RS13630	COG2866	Carboxypeptidase
FG173_RS13635	COG4948	Mandelate Racemase Muconate Lactonizing
FG173_RS13640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FG173_RS13655	COG3106	COG3106 Predicted ATPase
FG173_RS13665	COG1983	PspC domain protein
FG173_RS13685	COG0738	Major facilitator superfamily
FG173_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS13710	COG1469	GTP cyclohydrolase I activity
FG173_RS13725	COG4171	peptide transport system, permease
FG173_RS13730	COG4172	Belongs to the ABC transporter superfamily
FG173_RS13745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FG173_RS13745	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FG173_RS13760	COG0243	molybdopterin cofactor binding
FG173_RS13775	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FG173_RS13780	COG0477	Major facilitator Superfamily
FG173_RS13785	COG1473	amidohydrolase
FG173_RS13790	COG1966	Carbon starvation protein
FG173_RS13795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FG173_RS13800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FG173_RS13805	COG1882	Formate acetyltransferase
FG173_RS13810	COG1349	DNA-binding transcription factor activity
FG173_RS13820	COG0023	Translation Initiation Factor
FG173_RS13840	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FG173_RS13845	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FG173_RS13850	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS13860	COG1172	Belongs to the binding-protein-dependent transport system permease family
FG173_RS13865	COG1129	ABC transporter
FG173_RS13875	COG1879	ABC-type sugar transport system periplasmic component
FG173_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS13885	COG3958	Transketolase
FG173_RS13890	COG3959	Transketolase, thiamine diphosphate binding domain
FG173_RS13895	COG1349	DNA-binding transcription factor activity
FG173_RS13900	COG0671	phosphoesterase, PA-phosphatase related
FG173_RS13910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FG173_RS13920	COG0583	DNA-binding transcription factor activity
FG173_RS13935	COG0616	signal peptide processing
FG173_RS13940	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS13945	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FG173_RS13950	COG1187	pseudouridine synthase activity
FG173_RS13965	COG0009	L-threonylcarbamoyladenylate synthase
FG173_RS13970	COG0613	PHP domain protein
FG173_RS13985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FG173_RS13995	COG0133	tryptophan synthase activity
FG173_RS14000	COG0159	tryptophan synthase activity
FG173_RS14015	COG0727	PFAM Uncharacterised protein family (UPF0153)
FG173_RS14030	COG2917	probably involved in intracellular septation
FG173_RS14035	COG1607	acyl-coa hydrolase
FG173_RS14045	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FG173_RS14050	COG2350	Protein conserved in bacteria
FG173_RS14060	COG0583	DNA-binding transcription factor activity
FG173_RS14070	COG1609	Transcriptional regulator
FG173_RS14085	COG1070	Carbohydrate kinase
FG173_RS14090	COG1129	ABC transporter
FG173_RS14095	COG1172	Belongs to the binding-protein-dependent transport system permease family
FG173_RS14100	COG1879	ABC-type sugar transport system periplasmic component
FG173_RS14115	COG0783	Belongs to the Dps family
FG173_RS14125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FG173_RS14130	COG3099	Belongs to the UPF0263 family
FG173_RS14140	COG0444	Belongs to the ABC transporter superfamily
FG173_RS14145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FG173_RS14160	COG4166	transmembrane transport
FG173_RS14165	COG2095	MarC family integral membrane protein
FG173_RS14170	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS14170	COG1454	alcohol dehydrogenase
FG173_RS14195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FG173_RS14200	COG0745	RESPONSE REGULATOR receiver
FG173_RS14205	COG1752	Esterase of the alpha-beta hydrolase superfamily
FG173_RS14210	COG3012	SEC-C Motif Domain Protein
FG173_RS14215	COG0788	formyltetrahydrofolate deformylase activity
FG173_RS14255	COG0708	Exodeoxyribonuclease III
FG173_RS14260	COG0494	nUDIX hydrolase
FG173_RS14270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FG173_RS14285	COG0778	Nitroreductase
FG173_RS14295	COG0252	asparaginase activity
FG173_RS14300	COG1335	isochorismatase
FG173_RS14310	COG3139	Protein of unknown function (DUF1315)
FG173_RS14315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FG173_RS14330	COG3713	MltA-interacting MipA family protein
FG173_RS14335	COG2766	serine protein kinase
FG173_RS14340	COG2718	Belongs to the UPF0229 family
FG173_RS14390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FG173_RS14395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FG173_RS14405	COG3443	Belongs to the bacterial solute-binding protein 9 family
FG173_RS14410	COG2719	SpoVR family
FG173_RS14415	COG2186	Transcriptional regulator
FG173_RS14425	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FG173_RS14440	COG2983	Belongs to the UPF0260 family
FG173_RS14445	COG0179	Fumarylacetoacetate (FAA) hydrolase
FG173_RS14450	COG2951	lytic endotransglycosylase activity
FG173_RS14455	COG3100	YcgL domain-containing protein
FG173_RS14460	COG0850	regulation of cytokinetic process
FG173_RS14465	COG2894	cell division
FG173_RS14470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FG173_RS14475	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FG173_RS14480	COG0318	PFAM AMP-dependent synthetase and ligase
FG173_RS14485	COG3065	identical protein binding
FG173_RS14495	COG1199	ATP-dependent helicase activity
FG173_RS14500	COG0251	oxidation-reduction process
FG173_RS14505	COG2076	Multidrug Resistance protein
FG173_RS14510	COG2076	Multidrug Resistance protein
FG173_RS14515	COG0800	Aldolase
FG173_RS14520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FG173_RS14525	COG1737	Transcriptional regulator
FG173_RS14530	COG0469	pyruvate kinase activity
FG173_RS14540	COG1560	Kdo2-lipid A biosynthetic process
FG173_RS14545	COG0739	heme binding
FG173_RS14550	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FG173_RS14555	COG1121	(ABC) transporter
FG173_RS14560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FG173_RS14565	COG2255	four-way junction helicase activity
FG173_RS14570	COG0632	four-way junction helicase activity
FG173_RS14575	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FG173_RS14580	COG0217	transcriptional regulatory protein
FG173_RS14585	COG0494	nUDIX hydrolase
FG173_RS14590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FG173_RS14600	COG1335	isochorismatase
FG173_RS14610	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FG173_RS14615	COG2226	methyltransferase
FG173_RS14620	COG0500	methyltransferase
FG173_RS14645	COG3142	Participates in the control of copper homeostasis
FG173_RS14650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FG173_RS14655	COG3102	Protein conserved in bacteria
FG173_RS14660	COG0018	arginyl-trna synthetase
FG173_RS14670	COG0673	inositol 2-dehydrogenase activity
FG173_RS14675	COG3132	Protein of unknown function, DUF480
FG173_RS14680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FG173_RS14685	COG0477	Major facilitator Superfamily
FG173_RS14715	COG3097	Belongs to the UPF0267 family
FG173_RS14720	COG3141	response to X-ray
FG173_RS14725	COG0513	Belongs to the DEAD box helicase family
FG173_RS14735	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FG173_RS14740	COG3140	Belongs to the UPF0181 family
FG173_RS14745	COG1216	Glycosyl transferase, family 2
FG173_RS14755	COG0494	nUDIX hydrolase
FG173_RS14760	COG1760	l-serine dehydratase
FG173_RS14765	COG2200	EAL domain
FG173_RS14770	COG1253	flavin adenine dinucleotide binding
FG173_RS14780	COG3715	PTS system
FG173_RS14785	COG3716	PTS system mannose fructose sorbose family IID component
FG173_RS14790	COG4811	Protein of unknown function (DUF986)
FG173_RS14795	COG1971	Probably functions as a manganese efflux pump
FG173_RS14800	COG2226	methyltransferase
FG173_RS14805	COG1496	oxidoreductase activity
FG173_RS14830	COG1113	amino acid transport
FG173_RS14875	COG2207	Transcriptional regulator
FG173_RS14890	COG1652	LysM domain
FG173_RS14910	COG2988	succinylglutamate desuccinylase activity
FG173_RS14925	COG3138	arginine N-succinyltransferase
FG173_RS14930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FG173_RS14945	COG0444	Belongs to the ABC transporter superfamily
FG173_RS14955	COG0601	transmembrane transport
FG173_RS14965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FG173_RS14970	COG1271	oxidase subunit
FG173_RS15025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FG173_RS15030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FG173_RS15035	COG2181	nitrate reductase activity
FG173_RS15040	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FG173_RS15045	COG1140	nitrate reductase beta subunit
FG173_RS15090	COG0489	protein tyrosine kinase activity
FG173_RS15090	COG3206	protein involved in exopolysaccharide biosynthesis
FG173_RS15100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FG173_RS15105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FG173_RS15110	COG3710	Transcriptional regulator
FG173_RS15115	COG2223	nitrite transmembrane transporter activity
FG173_RS15120	COG3850	Histidine kinase
FG173_RS15125	COG2197	response regulator
FG173_RS15130	COG4932	domain protein
FG173_RS15135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FG173_RS15145	COG0747	negative chemotaxis
FG173_RS15150	COG4608	Belongs to the ABC transporter superfamily
FG173_RS15155	COG0444	Belongs to the ABC transporter superfamily
FG173_RS15165	COG0601	transmembrane transport
FG173_RS15185	COG0583	DNA-binding transcription factor activity
FG173_RS15190	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FG173_RS15195	COG4572	Cation transport regulator
FG173_RS15200	COG2375	cellular response to nickel ion
FG173_RS15205	COG0387	Pfam Sodium calcium exchanger
FG173_RS15215	COG1702	phosphate starvation-inducible protein PhoH
FG173_RS15225	COG2822	iron ion transport
FG173_RS15230	COG0672	)-iron permease
FG173_RS15240	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FG173_RS15240	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FG173_RS15240	COG0506	proline dehydrogenase activity
FG173_RS15250	COG1126	abc transporter atp-binding protein
FG173_RS15255	COG0765	amino acid transport
FG173_RS15260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FG173_RS15265	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FG173_RS15310	COG0583	DNA-binding transcription factor activity
FG173_RS15320	COG1677	Flagellar hook-basal body complex protein FliE
FG173_RS15330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FG173_RS15340	COG1157	protein secretion by the type III secretion system
FG173_RS15345	COG2882	bacterial-type flagellum organization
FG173_RS15395	COG1256	bacterial-type flagellum assembly
FG173_RS15430	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FG173_RS15435	COG1558	bacterial-type flagellum-dependent cell motility
FG173_RS15440	COG1815	bacterial-type flagellum-dependent cell motility
FG173_RS15450	COG2747	anti-sigma28 factor FlgM
FG173_RS15455	COG3418	PFAM FlgN family protein
FG173_RS15475	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FG173_RS15480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FG173_RS15485	COG1487	ribonuclease activity
FG173_RS15495	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FG173_RS15500	COG0745	RESPONSE REGULATOR receiver
FG173_RS15510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FG173_RS15515	COG0840	transmembrane signaling receptor activity
FG173_RS15520	COG0840	transmembrane signaling receptor activity
FG173_RS15525	COG0835	chemotaxis
FG173_RS15530	COG0643	Histidine kinase
FG173_RS15530	COG2198	Histidine kinase
FG173_RS15560	COG0589	response to stress
FG173_RS15565	COG2130	NADP-dependent
FG173_RS15570	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FG173_RS15755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FG173_RS15760	COG3483	tryptophan 2,3-dioxygenase activity
FG173_RS15765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FG173_RS15775	COG3059	membrane
FG173_RS15780	COG2207	Transcriptional regulator
FG173_RS15785	COG1609	Transcriptional regulator
FG173_RS15805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FG173_RS15815	COG3712	iron ion homeostasis
FG173_RS15820	COG1595	DNA-templated transcription, initiation
FG173_RS15825	COG1629	transport
FG173_RS15830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FG173_RS15870	COG3781	membrane
FG173_RS15875	COG2837	iron assimilation
FG173_RS15885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FG173_RS15895	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FG173_RS15930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FG173_RS15940	COG0076	glutamate decarboxylase activity
FG173_RS15975	COG3321	synthase
FG173_RS15975	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS15975	COG0604	alcohol dehydrogenase
FG173_RS15985	COG0583	DNA-binding transcription factor activity
FG173_RS15990	COG3753	Protein conserved in bacteria
FG173_RS15995	COG2261	transglycosylase associated protein
FG173_RS16005	COG1560	Kdo2-lipid A biosynthetic process
FG173_RS16010	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FG173_RS16020	COG4251	negative regulation of phosphorylation
FG173_RS16020	COG2203	Gaf domain
FG173_RS16020	COG5001	Diguanylate cyclase
FG173_RS16020	COG3706	GGDEF domain
FG173_RS16030	COG2030	dehydratase
FG173_RS16030	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS16035	COG3396	Phenylacetate-CoA oxygenase
FG173_RS16040	COG3460	Phenylacetate-CoA oxygenase
FG173_RS16045	COG3396	Phenylacetate-CoA oxygenase
FG173_RS16050	COG2151	metal-sulfur cluster biosynthetic enzyme
FG173_RS16055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FG173_RS16060	COG1024	Enoyl-CoA hydratase
FG173_RS16065	COG1024	Enoyl-CoA hydratase
FG173_RS16070	COG1250	3-hydroxyacyl-CoA dehydrogenase
FG173_RS16075	COG2050	protein possibly involved in aromatic compounds catabolism
FG173_RS16080	COG0183	Belongs to the thiolase family
FG173_RS16085	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FG173_RS16090	COG3327	negative regulation of DNA-templated transcription, initiation
FG173_RS16095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FG173_RS16100	COG1113	amino acid transport
FG173_RS16120	COG0583	DNA-binding transcription factor activity
FG173_RS16125	COG0625	glutathione transferase activity
FG173_RS16160	COG0583	DNA-binding transcription factor activity
FG173_RS16180	COG4122	O-methyltransferase activity
FG173_RS16185	COG2207	Transcriptional regulator
FG173_RS16185	COG3708	Transcriptional regulator
FG173_RS16200	COG0667	Aldo Keto reductase
FG173_RS16205	COG4772	TonB-dependent receptor
FG173_RS16210	COG4993	Dehydrogenase
FG173_RS16245	COG3539	Fimbrial protein
FG173_RS16255	COG3121	Chaperone
FG173_RS16260	COG3188	usher protein
FG173_RS16265	COG3539	Fimbrial protein
FG173_RS16280	COG0534	Mate efflux family protein
FG173_RS16345	COG0561	phosphatase activity
FG173_RS16360	COG2197	response regulator
FG173_RS16480	COG3228	Belongs to the MtfA family
FG173_RS16490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FG173_RS16505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FG173_RS16510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FG173_RS16515	COG1116	anion transmembrane transporter activity
FG173_RS16520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FG173_RS16525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FG173_RS16540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FG173_RS16555	COG3238	Protein conserved in bacteria
FG173_RS16560	COG1247	-acetyltransferase
FG173_RS16580	COG0583	DNA-binding transcription factor activity
FG173_RS16590	COG1802	Transcriptional regulator
FG173_RS16610	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS16635	COG0859	PFAM glycosyl transferase family 9
FG173_RS16655	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FG173_RS16675	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS16680	COG1169	isochorismate synthase
FG173_RS16705	COG0471	metal ion transport
FG173_RS16710	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FG173_RS16720	COG3051	citrate lyase alpha subunit
FG173_RS16725	COG2301	Belongs to the HpcH HpaI aldolase family
FG173_RS16730	COG3052	prosthetic group binding
FG173_RS16735	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FG173_RS16740	COG4565	transcriptional regulatory protein
FG173_RS16745	COG3250	beta-galactosidase activity
FG173_RS16755	COG0300	oxidoreductase activity
FG173_RS16760	COG2207	Transcriptional regulator
FG173_RS16765	COG0667	Aldo Keto reductase
FG173_RS16775	COG1064	alcohol dehydrogenase
FG173_RS16815	COG2999	glutathione oxidoreductase activity
FG173_RS16840	COG0583	DNA-binding transcription factor activity
FG173_RS16845	COG2197	response regulator
FG173_RS16855	COG1121	(ABC) transporter
FG173_RS16860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS16875	COG2814	Major facilitator Superfamily
FG173_RS16880	COG0860	N-Acetylmuramoyl-L-alanine amidase
FG173_RS16895	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS16900	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FG173_RS16955	COG2271	Major facilitator Superfamily
FG173_RS16975	COG0411	ABC transporter
FG173_RS17025	COG0583	DNA-binding transcription factor activity
FG173_RS17035	COG0456	acetyltransferase
FG173_RS17040	COG0318	PFAM AMP-dependent synthetase and ligase
FG173_RS17050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FG173_RS17055	COG0156	8-amino-7-oxononanoate synthase activity
FG173_RS17065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FG173_RS17070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FG173_RS17075	COG2244	polysaccharide biosynthetic process
FG173_RS17085	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FG173_RS17090	COG0795	lipopolysaccharide-transporting ATPase activity
FG173_RS17105	COG0626	cystathionine gamma-synthase activity
FG173_RS17135	COG0583	DNA-binding transcription factor activity
FG173_RS17145	COG1609	Transcriptional regulator
FG173_RS17155	COG3623	hexulose-6-phosphate isomerase
FG173_RS17165	COG1172	Belongs to the binding-protein-dependent transport system permease family
FG173_RS17175	COG1879	ABC-type sugar transport system periplasmic component
FG173_RS17180	COG1063	alcohol dehydrogenase
FG173_RS17190	COG1473	amidohydrolase
FG173_RS17195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FG173_RS17200	COG2926	Belongs to the UPF0265 family
FG173_RS17205	COG1289	transmembrane transporter activity
FG173_RS17210	COG3023	N-Acetylmuramoyl-L-alanine amidase
FG173_RS17235	COG2925	Exonuclease
FG173_RS17240	COG0531	amino acid
FG173_RS17250	COG0174	glutamine synthetase
FG173_RS17255	COG1917	Cupin 2, conserved barrel domain protein
FG173_RS17255	COG1396	sequence-specific DNA binding
FG173_RS17260	COG1129	ABC transporter
FG173_RS17265	COG1172	Belongs to the binding-protein-dependent transport system permease family
FG173_RS17270	COG4771	TonB-dependent receptor
FG173_RS17285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS17295	COG0833	amino acid
FG173_RS17300	COG0583	DNA-binding transcription factor activity
FG173_RS17310	COG2855	membrane
FG173_RS17315	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FG173_RS17325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FG173_RS17325	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FG173_RS17325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FG173_RS17330	COG1105	Belongs to the carbohydrate kinase PfkB family
FG173_RS17335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FG173_RS17335	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FG173_RS17340	COG0494	nUDIX hydrolase
FG173_RS17345	COG3005	denitrification pathway
FG173_RS17350	COG0243	molybdopterin cofactor binding
FG173_RS17370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FG173_RS17375	COG1312	Catalyzes the dehydration of D-mannonate
FG173_RS17380	COG0246	Mannitol dehydrogenase
FG173_RS17390	COG0523	cobalamin synthesis protein
FG173_RS17395	COG0671	phosphoesterase, PA-phosphatase related
FG173_RS17405	COG0791	NLP P60 protein
FG173_RS17410	COG2200	EAL domain
FG173_RS17415	COG4166	transmembrane transport
FG173_RS17420	COG4174	ABC transporter (Permease)
FG173_RS17425	COG4239	(ABC) transporter, permease
FG173_RS17430	COG4172	Belongs to the ABC transporter superfamily
FG173_RS17440	COG2814	Major facilitator Superfamily
FG173_RS17445	COG1187	pseudouridine synthase activity
FG173_RS17450	COG1061	Type III restriction enzyme res subunit
FG173_RS17455	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FG173_RS17460	COG3081	Nucleoid-associated protein
FG173_RS17465	COG3082	Protein of unknown function (DUF1414)
FG173_RS17470	COG3083	sulfuric ester hydrolase activity
FG173_RS17525	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FG173_RS17540	COG0346	lactoylglutathione lyase activity
FG173_RS17555	COG2223	nitrite transmembrane transporter activity
FG173_RS17560	COG2198	Histidine kinase
FG173_RS17560	COG0642	Histidine kinase
FG173_RS17565	COG2197	response regulator
FG173_RS17570	COG0784	Response regulator, receiver
FG173_RS17570	COG2205	protein histidine kinase activity
FG173_RS17580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FG173_RS17585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FG173_RS17595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FG173_RS17620	COG0814	amino acid
FG173_RS17645	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FG173_RS17650	COG0596	Alpha beta hydrolase
FG173_RS17655	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FG173_RS17660	COG4575	ribosome binding
FG173_RS17665	COG1063	alcohol dehydrogenase
FG173_RS17670	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS17675	COG1609	Transcriptional regulator
FG173_RS17705	COG0028	Belongs to the TPP enzyme family
FG173_RS17710	COG0583	DNA-binding transcription factor activity
FG173_RS17715	COG1007	ATP synthesis coupled electron transport
FG173_RS17720	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FG173_RS17730	COG0713	ATP synthesis coupled electron transport
FG173_RS17735	COG0839	Belongs to the complex I subunit 6 family
FG173_RS17745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FG173_RS17750	COG1034	ATP synthesis coupled electron transport
FG173_RS17765	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FG173_RS17765	COG0649	NAD binding
FG173_RS17770	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FG173_RS17775	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FG173_RS17780	COG0583	DNA-binding transcription factor activity
FG173_RS17785	COG0436	Aminotransferase
FG173_RS17790	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FG173_RS17795	COG0471	metal ion transport
FG173_RS17795	COG0490	domain, Protein
FG173_RS17800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FG173_RS17805	COG3013	Belongs to the UPF0304 family
FG173_RS17810	COG3092	negative regulation of chromosome organization
FG173_RS17815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FG173_RS17820	COG0857	belongs to the CobB CobQ family
FG173_RS17820	COG0280	phosphate acetyltransferase
FG173_RS17830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FG173_RS17835	COG3959	Transketolase, thiamine diphosphate binding domain
FG173_RS17840	COG3037	sugar-specific permease SgaT UlaA
FG173_RS17850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FG173_RS17855	COG1609	Transcriptional regulator
FG173_RS17860	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FG173_RS17865	COG0622	Phosphoesterase
FG173_RS17870	COG0625	glutathione transferase activity
FG173_RS17875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FG173_RS17880	COG1090	epimerase
FG173_RS17885	COG4598	ABC transporter
FG173_RS17895	COG4215	(ABC) transporter
FG173_RS17900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FG173_RS17905	COG0163	prenyltransferase activity
FG173_RS17910	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FG173_RS17915	COG1286	toxin biosynthetic process
FG173_RS17935	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FG173_RS17940	COG0285	dihydrofolate synthase activity
FG173_RS17945	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FG173_RS17950	COG0586	Pfam SNARE associated Golgi protein
FG173_RS17960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FG173_RS17965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FG173_RS17975	COG0697	spore germination
FG173_RS17980	COG0642	Histidine kinase
FG173_RS18025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FG173_RS18065	COG2195	Cleaves the N-terminal amino acid of tripeptides
FG173_RS18070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FG173_RS18085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FG173_RS18100	COG3101	peptidyl-lysine hydroxylation
FG173_RS18105	COG0730	response to heat
FG173_RS18110	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FG173_RS18115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FG173_RS18120	COG2890	protein-(glutamine-N5) methyltransferase activity
FG173_RS18125	COG2840	Smr protein MutS2
FG173_RS18130	COG2062	phosphohistidine phosphatase, SixA
FG173_RS18135	COG1024	Enoyl-CoA hydratase
FG173_RS18135	COG1250	3-hydroxyacyl-CoA dehydrogenase
FG173_RS18140	COG0183	Belongs to the thiolase family
FG173_RS18145	COG3691	Protein conserved in bacteria
FG173_RS18160	COG3088	subunit of a heme lyase
FG173_RS18160	COG4235	cytochrome complex assembly
FG173_RS18165	COG3088	subunit of a heme lyase
FG173_RS18165	COG4235	cytochrome complex assembly
FG173_RS18170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FG173_RS18175	COG1138	Cytochrome C-type biogenesis protein
FG173_RS18180	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FG173_RS18185	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FG173_RS18190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FG173_RS18195	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FG173_RS18205	COG2116	formate transmembrane transporter activity
FG173_RS18215	COG2706	6-phosphogluconolactonase activity
FG173_RS18235	COG2197	response regulator
FG173_RS18255	COG0583	DNA-binding transcription factor activity
FG173_RS18265	COG0697	spore germination
FG173_RS18280	COG2951	lytic endotransglycosylase activity
FG173_RS18290	COG1598	PFAM Uncharacterised protein family UPF0150
FG173_RS18300	COG3038	cytochrome b561
FG173_RS18305	COG0436	Aminotransferase
FG173_RS18320	COG3275	phosphorelay sensor kinase activity
FG173_RS18325	COG3279	Response regulator of the LytR AlgR family
FG173_RS18335	COG2223	nitrite transmembrane transporter activity
FG173_RS18350	COG1794	racemase activity, acting on amino acids and derivatives
FG173_RS18365	COG3961	Belongs to the TPP enzyme family
FG173_RS18370	COG0667	Aldo Keto reductase
FG173_RS18380	COG1914	H( )-stimulated, divalent metal cation uptake system
FG173_RS18385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FG173_RS18400	COG3121	Chaperone
FG173_RS18425	COG2116	formate transmembrane transporter activity
FG173_RS18430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FG173_RS18460	COG4592	Periplasmic binding protein
FG173_RS18465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS18470	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS18475	COG1120	ATPase activity
FG173_RS18480	COG0747	negative chemotaxis
FG173_RS18500	COG4302	ethanolamine ammonia-lyase activity
FG173_RS18505	COG4303	Ethanolamine ammonia lyase large subunit
FG173_RS18525	COG0385	Bile acid
FG173_RS18530	COG3530	Putative quorum-sensing-regulated virulence factor
FG173_RS18535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FG173_RS18540	COG3115	cell septum assembly
FG173_RS18545	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FG173_RS18555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FG173_RS18560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FG173_RS18570	COG2205	protein histidine kinase activity
FG173_RS18575	COG0745	RESPONSE REGULATOR receiver
FG173_RS18590	COG4208	sulfate ABC transporter
FG173_RS18595	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FG173_RS18605	COG2837	iron assimilation
FG173_RS18620	COG3111	PFAM Bacterial OB fold (BOF) protein
FG173_RS18625	COG0456	acetyltransferase
FG173_RS18630	COG0860	N-Acetylmuramoyl-L-alanine amidase
FG173_RS18635	COG0408	coproporphyrinogen oxidase activity
FG173_RS18640	COG1671	Belongs to the UPF0178 family
FG173_RS18650	COG1770	oligopeptidase
FG173_RS18665	COG0833	amino acid
FG173_RS18670	COG2040	homocysteine
FG173_RS18700	COG0583	DNA-binding transcription factor activity
FG173_RS18705	COG3397	chitin binding
FG173_RS18720	COG2376	Dihydroxyacetone kinase
FG173_RS18725	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS18730	COG2814	Major facilitator Superfamily
FG173_RS18735	COG1063	alcohol dehydrogenase
FG173_RS18740	COG0698	ribose 5-phosphate isomerase
FG173_RS18745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FG173_RS18750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FG173_RS18755	COG0494	nUDIX hydrolase
FG173_RS18760	COG3850	Histidine kinase
FG173_RS18765	COG2197	response regulator
FG173_RS18775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FG173_RS18795	COG0454	-acetyltransferase
FG173_RS18805	COG1393	Belongs to the ArsC family
FG173_RS18810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FG173_RS18815	COG1876	peptidase activity
FG173_RS18825	COG0400	carboxylic ester hydrolase activity
FG173_RS18835	COG2321	neutral zinc metallopeptidase
FG173_RS18840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FG173_RS18845	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FG173_RS18850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FG173_RS18855	COG2716	regulation of RNA biosynthetic process
FG173_RS18860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FG173_RS18865	COG0628	permease
FG173_RS18915	COG4783	chaperone-mediated protein folding
FG173_RS18920	COG1393	Belongs to the ArsC family
FG173_RS18925	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FG173_RS18935	COG2261	transglycosylase associated protein
FG173_RS18945	COG2233	PERMEase
FG173_RS18950	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FG173_RS18955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FG173_RS18960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FG173_RS18965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FG173_RS18990	COG0573	inorganic phosphate transmembrane transporter activity
FG173_RS18995	COG0573	inorganic phosphate transmembrane transporter activity
FG173_RS19000	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FG173_RS19015	COG2239	Acts as a magnesium transporter
FG173_RS19020	COG3447	MASE1 domain protein
FG173_RS19020	COG5002	protein histidine kinase activity
FG173_RS19020	COG5001	Diguanylate cyclase
FG173_RS19035	COG0443	Heat shock 70 kDa protein
FG173_RS19050	COG0667	Aldo Keto reductase
FG173_RS19055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FG173_RS19060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FG173_RS19065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FG173_RS19070	COG2814	Major facilitator Superfamily
FG173_RS19075	COG2205	protein histidine kinase activity
FG173_RS19080	COG0745	RESPONSE REGULATOR receiver
FG173_RS19095	COG3422	double-strand break repair
FG173_RS19100	COG0826	peptidase U32
FG173_RS19105	COG1597	lipid kinase activity
FG173_RS19110	COG4948	Mandelate Racemase Muconate Lactonizing
FG173_RS19115	COG1063	alcohol dehydrogenase
FG173_RS19120	COG2271	Major facilitator Superfamily
FG173_RS19135	COG1802	Transcriptional regulator
FG173_RS19140	COG1830	Aldolase
FG173_RS19145	COG3730	PTS system glucitol sorbitol-specific
FG173_RS19160	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS19165	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FG173_RS19170	COG1349	DNA-binding transcription factor activity
FG173_RS19185	COG0351	phosphomethylpyrimidine kinase
FG173_RS19190	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FG173_RS19205	COG2814	Major facilitator Superfamily
FG173_RS19230	COG1187	pseudouridine synthase activity
FG173_RS19250	COG2205	protein histidine kinase activity
FG173_RS19250	COG2198	Histidine kinase
FG173_RS19250	COG0784	Response regulator, receiver
FG173_RS19255	COG5285	phytanoyl-CoA dioxygenase
FG173_RS19265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FG173_RS19265	COG0519	Catalyzes the synthesis of GMP from XMP
FG173_RS19270	COG0516	GMP reductase activity
FG173_RS19270	COG0517	IMP dehydrogenase activity
FG173_RS19280	COG1570	exodeoxyribonuclease VII activity
FG173_RS19290	COG2271	Major facilitator Superfamily
FG173_RS19295	COG1609	Transcriptional regulator
FG173_RS19310	COG1645	bacterial-type flagellum-dependent swarming motility
FG173_RS19320	COG1160	GTP binding
FG173_RS19330	COG2976	Protein conserved in bacteria
FG173_RS19335	COG0124	histidyl-tRNA synthetase
FG173_RS19340	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FG173_RS19355	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FG173_RS19360	COG0105	UTP biosynthetic process
FG173_RS19375	COG2975	iron-sulfur cluster assembly
FG173_RS19380	COG0633	Ferredoxin
FG173_RS19385	COG0443	Heat shock 70 kDa protein
FG173_RS19390	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FG173_RS19395	COG0316	Belongs to the HesB IscA family
FG173_RS19400	COG0822	iron-sulfur transferase activity
FG173_RS19405	COG1104	cysteine desulfurase activity
FG173_RS19410	COG1959	2 iron, 2 sulfur cluster binding
FG173_RS19425	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FG173_RS19430	COG3683	transport system, periplasmic component
FG173_RS19435	COG3711	transcriptional antiterminator
FG173_RS19440	COG2814	Major facilitator Superfamily
FG173_RS19445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FG173_RS19450	COG1017	nitric oxide dioxygenase activity
FG173_RS19450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FG173_RS19460	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FG173_RS19465	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS19470	COG1177	transmembrane transport
FG173_RS19480	COG3842	ATPase activity
FG173_RS19485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FG173_RS19495	COG0583	DNA-binding transcription factor activity
FG173_RS19500	COG0347	Belongs to the P(II) protein family
FG173_RS19505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FG173_RS19505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FG173_RS19510	COG2204	response regulator
FG173_RS19515	COG3170	Tfp pilus assembly protein FimV
FG173_RS19520	COG2205	protein histidine kinase activity
FG173_RS19530	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FG173_RS19555	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FG173_RS19560	COG1737	Transcriptional regulator
FG173_RS19565	COG2194	sulfuric ester hydrolase activity
FG173_RS19570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FG173_RS19575	COG0736	holo-[acyl-carrier-protein] synthase activity
FG173_RS19580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FG173_RS19585	COG1381	Involved in DNA repair and RecF pathway recombination
FG173_RS19590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FG173_RS19595	COG0571	ribonuclease III activity
FG173_RS19605	COG0481	GTPase activity
FG173_RS19615	COG3086	response to oxidative stress
FG173_RS19620	COG3026	antisigma factor binding
FG173_RS19635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FG173_RS19640	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FG173_RS19645	COG0513	Belongs to the DEAD box helicase family
FG173_RS19665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FG173_RS19675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FG173_RS19680	COG0497	DNA recombination
FG173_RS19685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FG173_RS19690	COG2914	Belongs to the UPF0125 (RnfH) family
FG173_RS19695	COG2867	negative regulation of translational initiation
FG173_RS19700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FG173_RS19710	COG1566	PFAM secretion protein HlyD family protein
FG173_RS19725	COG0583	DNA-binding transcription factor activity
FG173_RS19730	COG3182	Iron-regulated membrane protein
FG173_RS19740	COG0454	-acetyltransferase
FG173_RS19770	COG2388	GCN5-related N-acetyl-transferase
FG173_RS19775	COG3592	Divergent 4Fe-4S mono-cluster
FG173_RS19780	COG2259	Doxx family
FG173_RS19785	COG2840	Smr protein MutS2
FG173_RS19805	COG0477	Major facilitator Superfamily
FG173_RS19815	COG0477	Major facilitator Superfamily
FG173_RS19830	COG4575	ribosome binding
FG173_RS19840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FG173_RS19845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FG173_RS19850	COG1780	Probably involved in ribonucleotide reductase function
FG173_RS19870	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS19885	COG1752	Esterase of the alpha-beta hydrolase superfamily
FG173_RS19890	COG3493	citrate carrier protein
FG173_RS19915	COG4176	ABC-type proline glycine betaine transport system permease component
FG173_RS19920	COG2113	Glycine betaine
FG173_RS19935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FG173_RS19955	COG1566	PFAM secretion protein HlyD family protein
FG173_RS19970	COG3118	belongs to the thioredoxin family
FG173_RS20030	COG2011	ABC-type metal ion transport system permease component
FG173_RS20060	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FG173_RS20075	COG4568	rho-dependent transcription termination
FG173_RS20090	COG3104	oligopeptide transport
FG173_RS20110	COG0346	lactoylglutathione lyase activity
FG173_RS20120	COG0825	malonyl-CoA metabolic process
FG173_RS20130	COG0587	DNA-directed DNA polymerase activity
FG173_RS20135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FG173_RS20140	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FG173_RS20145	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FG173_RS20150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FG173_RS20155	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FG173_RS20160	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FG173_RS20170	COG0750	zinc metalloprotease
FG173_RS20180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FG173_RS20195	COG0528	UMP kinase activity
FG173_RS20205	COG0052	Belongs to the universal ribosomal protein uS2 family
FG173_RS20215	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FG173_RS20235	COG0564	pseudouridine synthase activity
FG173_RS20245	COG2373	Large extracellular alpha-helical protein
FG173_RS20250	COG3098	single-species biofilm formation
FG173_RS20255	COG2814	Major facilitator Superfamily
FG173_RS20270	COG1611	Belongs to the LOG family
FG173_RS20280	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FG173_RS20285	COG2363	Small membrane protein
FG173_RS20290	COG0583	DNA-binding transcription factor activity
FG173_RS20300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FG173_RS20305	COG2166	iron-sulfur cluster assembly
FG173_RS20315	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FG173_RS20335	COG0860	N-Acetylmuramoyl-L-alanine amidase
FG173_RS20340	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FG173_RS20340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FG173_RS20345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FG173_RS20350	COG1074	ATP-dependent DNA helicase activity
FG173_RS20355	COG1025	Belongs to the peptidase M16 family
FG173_RS20360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FG173_RS20380	COG2165	general secretion pathway protein
FG173_RS20385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FG173_RS20390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FG173_RS20400	COG0494	nUDIX hydrolase
FG173_RS20415	COG0861	Integral membrane protein TerC family
FG173_RS20425	COG0667	Aldo Keto reductase
FG173_RS20430	COG0477	Major facilitator Superfamily
FG173_RS20435	COG0318	PFAM AMP-dependent synthetase and ligase
FG173_RS20435	COG0204	Acyl-transferase
FG173_RS20445	COG1609	Transcriptional regulator
FG173_RS20455	COG0583	DNA-binding transcription factor activity
FG173_RS20460	COG0583	DNA-binding transcription factor activity
FG173_RS20480	COG4178	(ABC) transporter
FG173_RS20490	COG3716	PTS system mannose fructose sorbose family IID component
FG173_RS20495	COG3715	PTS system
FG173_RS20500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FG173_RS20510	COG1349	DNA-binding transcription factor activity
FG173_RS20530	COG0582	viral genome integration into host DNA
FG173_RS20535	COG2197	response regulator
FG173_RS20540	COG2197	response regulator
FG173_RS20560	COG3121	Chaperone
FG173_RS20570	COG0582	viral genome integration into host DNA
FG173_RS20575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FG173_RS20580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FG173_RS20595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FG173_RS20620	COG0583	DNA-binding transcription factor activity
FG173_RS20625	COG1620	l-lactate permease
FG173_RS20630	COG1304	FMN binding
FG173_RS20640	COG2814	Major facilitator Superfamily
FG173_RS20650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FG173_RS20655	COG1309	transcriptional regulator
FG173_RS20660	COG5265	(ABC) transporter
FG173_RS20665	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FG173_RS20670	COG4942	peptidase
FG173_RS20675	COG3247	response to pH
FG173_RS20695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FG173_RS20705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FG173_RS20715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FG173_RS20735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FG173_RS20740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FG173_RS20745	COG4974	Belongs to the 'phage' integrase family
FG173_RS20750	COG0716	FMN binding
FG173_RS20760	COG2205	protein histidine kinase activity
FG173_RS20765	COG0745	RESPONSE REGULATOR receiver
FG173_RS20775	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FG173_RS20780	COG0354	folic acid binding
FG173_RS20790	COG1272	protein, Hemolysin III
FG173_RS20800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FG173_RS20805	COG1940	carbohydrate kinase activity
FG173_RS20810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FG173_RS20820	COG1172	Belongs to the binding-protein-dependent transport system permease family
FG173_RS20825	COG1129	ABC transporter
FG173_RS20835	COG1349	DNA-binding transcription factor activity
FG173_RS20850	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS20880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FG173_RS20880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FG173_RS20885	COG0509	glycine decarboxylation via glycine cleavage system
FG173_RS20890	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FG173_RS20895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FG173_RS20900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FG173_RS20905	COG0006	proline dipeptidase activity
FG173_RS20910	COG3079	Belongs to the UPF0149 family
FG173_RS20925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FG173_RS20930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FG173_RS20940	COG0583	DNA-binding transcription factor activity
FG173_RS20950	COG1279	arginine transmembrane transporter activity
FG173_RS20960	COG3122	Protein conserved in bacteria
FG173_RS20975	COG2271	Major facilitator Superfamily
FG173_RS20995	COG0191	fructose-bisphosphate aldolase activity
FG173_RS21000	COG0126	phosphoglycerate kinase activity
FG173_RS21005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FG173_RS21010	COG0583	DNA-binding transcription factor activity
FG173_RS21015	COG0473	3-isopropylmalate dehydrogenase activity
FG173_RS21025	COG4638	Rieske (2fe-2S)
FG173_RS21035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FG173_RS21040	COG3842	ATPase activity
FG173_RS21045	COG1175	transmembrane transport
FG173_RS21060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FG173_RS21070	COG1114	Component of the transport system for branched-chain amino acids
FG173_RS21080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FG173_RS21085	COG0501	Belongs to the peptidase M48B family
FG173_RS21100	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FG173_RS21105	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS21110	COG2267	carboxylic ester hydrolase activity
FG173_RS21135	COG1414	Transcriptional regulator
FG173_RS21140	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS21155	COG2146	nitrite reductase [NAD(P)H] activity
FG173_RS21160	COG2271	Major facilitator Superfamily
FG173_RS21170	COG0010	Belongs to the arginase family
FG173_RS21175	COG1166	arginine decarboxylase activity
FG173_RS21185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FG173_RS21195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FG173_RS21200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FG173_RS21205	COG1120	ATPase activity
FG173_RS21210	COG4774	siderophore transport
FG173_RS21220	COG1643	Atp-dependent helicase
FG173_RS21225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FG173_RS21230	COG1489	DNA binding
FG173_RS21240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FG173_RS21245	COG0617	tRNA 3'-terminal CCA addition
FG173_RS21250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FG173_RS21255	COG0642	Histidine kinase
FG173_RS21265	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FG173_RS21270	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FG173_RS21275	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FG173_RS21280	COG0726	polysaccharide deacetylase
FG173_RS21285	COG0842	Transport permease protein
FG173_RS21290	COG1131	(ABC) transporter
FG173_RS21295	COG0288	reversible hydration of carbon dioxide
FG173_RS21315	COG2132	Multicopper oxidase
FG173_RS21325	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FG173_RS21330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FG173_RS21335	COG3112	Uncharacterised protein family (UPF0231)
FG173_RS21350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FG173_RS21355	COG0508	dehydrogenase complex catalyzes the overall conversion of
FG173_RS21360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FG173_RS21365	COG2186	Transcriptional regulator
FG173_RS21370	COG1113	amino acid transport
FG173_RS21375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FG173_RS21375	COG2010	Cytochrome c
FG173_RS21385	COG2010	Cytochrome c
FG173_RS21385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FG173_RS21395	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FG173_RS21400	COG2207	Transcriptional regulator
FG173_RS21400	COG3708	Transcriptional regulator
FG173_RS21410	COG3091	SprT-like family
FG173_RS21415	COG2356	endonuclease I
FG173_RS21420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FG173_RS21425	COG0189	ligase activity
FG173_RS21430	COG1678	Uncharacterized ACR, COG1678
FG173_RS21435	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FG173_RS21445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FG173_RS21460	COG1872	DUF167
FG173_RS21470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FG173_RS21485	COG2066	Belongs to the glutaminase family
FG173_RS21490	COG3171	Protein conserved in bacteria
FG173_RS21495	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FG173_RS21505	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FG173_RS21510	COG0741	lytic transglycosylase activity
FG173_RS21535	COG2819	hydrolase of the alpha beta superfamily
FG173_RS21540	COG0454	-acetyltransferase
FG173_RS21565	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FG173_RS21565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FG173_RS21600	COG0848	biopolymer transport protein
FG173_RS21615	COG0586	Pfam SNARE associated Golgi protein
FG173_RS21620	COG0583	DNA-binding transcription factor activity
FG173_RS21630	COG2207	Transcriptional regulator
FG173_RS21640	COG0656	L-ascorbic acid biosynthetic process
FG173_RS21645	COG0741	lytic transglycosylase activity
FG173_RS21655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FG173_RS21665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FG173_RS21670	COG2211	Major facilitator Superfamily
FG173_RS21675	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FG173_RS21680	COG0583	DNA-binding transcription factor activity
FG173_RS21685	COG2132	Multicopper oxidase
FG173_RS21690	COG0204	Acyl-transferase
FG173_RS21700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FG173_RS21705	COG2249	NAD(P)H dehydrogenase (quinone) activity
FG173_RS21710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FG173_RS21715	COG0583	DNA-binding transcription factor activity
FG173_RS21720	COG0187	DNA topoisomerase II activity
FG173_RS21725	COG3150	esterase
FG173_RS21730	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FG173_RS21735	COG3151	Protein conserved in bacteria
FG173_RS21740	COG0494	nUDIX hydrolase
FG173_RS21745	COG1538	Outer membrane efflux protein
FG173_RS21755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FG173_RS21755	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FG173_RS21755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FG173_RS21760	COG1461	Dihydroxyacetone kinase
FG173_RS21765	COG2376	Dihydroxyacetone kinase
FG173_RS21775	COG5463	Belongs to the UPF0441 family
FG173_RS21780	COG0754	glutathionylspermidine amidase activity
FG173_RS21785	COG3384	dioxygenase
FG173_RS21795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FG173_RS21805	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FG173_RS21805	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FG173_RS21810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FG173_RS21815	COG3025	triphosphatase activity
FG173_RS21820	COG4991	sh3 domain protein
FG173_RS21825	COG0617	tRNA 3'-terminal CCA addition
FG173_RS21830	COG1968	undecaprenyl-diphosphatase activity
FG173_RS21835	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FG173_RS21840	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FG173_RS21845	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FG173_RS21850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FG173_RS21855	COG0358	DNA primase activity
FG173_RS22005	COG4695	Portal protein
FG173_RS22030	COG0758	DNA mediated transformation
FG173_RS22030	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FG173_RS22060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FG173_RS22095	COG4974	Belongs to the 'phage' integrase family
FG173_RS22115	COG0625	glutathione transferase activity
FG173_RS22125	COG1012	belongs to the aldehyde dehydrogenase family
FG173_RS22130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FG173_RS22140	COG0488	(ABC) transporter
FG173_RS22145	COG1902	pentaerythritol trinitrate reductase activity
FG173_RS22145	COG0446	pyridine nucleotide-disulphide oxidoreductase
FG173_RS22150	COG2813	Specifically methylates the guanine in position
FG173_RS22155	COG1451	nucleotide metabolic process
FG173_RS22160	COG0673	inositol 2-dehydrogenase activity
FG173_RS22165	COG0519	Catalyzes the synthesis of GMP from XMP
FG173_RS22165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FG173_RS22170	COG0861	Integral membrane protein TerC family
FG173_RS22175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FG173_RS22180	COG2721	sulfolactate sulfo-lyase activity
FG173_RS22185	COG1904	glucuronate isomerase
FG173_RS22190	COG2271	Major facilitator Superfamily
FG173_RS22205	COG0586	Pfam SNARE associated Golgi protein
FG173_RS22210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FG173_RS22220	COG4575	ribosome binding
FG173_RS22225	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FG173_RS22235	COG2259	Doxx family
FG173_RS22240	COG0435	Glutathione S-transferase
FG173_RS22245	COG0583	DNA-binding transcription factor activity
FG173_RS22250	COG1741	Belongs to the pirin family
FG173_RS22265	COG3107	peptidoglycan biosynthetic process
FG173_RS22270	COG0792	nuclease activity
FG173_RS22275	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FG173_RS22280	COG2823	Periplasmic or secreted lipoprotein
FG173_RS22290	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FG173_RS22295	COG2198	Histidine kinase
FG173_RS22295	COG0784	Response regulator, receiver
FG173_RS22295	COG5002	protein histidine kinase activity
FG173_RS22300	COG1242	4 iron, 4 sulfur cluster binding
FG173_RS22305	COG0069	glutamate synthase activity
FG173_RS22305	COG0070	glutamate synthase
FG173_RS22305	COG0067	glutamate synthase
FG173_RS22310	COG0493	'glutamate synthase
FG173_RS22320	COG2969	positive regulation of protein catabolic process
FG173_RS22325	COG0625	glutathione transferase activity
FG173_RS22330	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FG173_RS22335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FG173_RS22345	COG3105	Protein conserved in bacteria
FG173_RS22355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FG173_RS22360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FG173_RS22365	COG5007	Belongs to the BolA IbaG family
FG173_RS22370	COG3113	response to antibiotic
FG173_RS22375	COG2854	intermembrane phospholipid transfer
FG173_RS22380	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FG173_RS22385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FG173_RS22390	COG1127	ABC transporter
FG173_RS22395	COG0530	calcium, potassium:sodium antiporter activity
FG173_RS22400	COG0517	IMP dehydrogenase activity
FG173_RS22400	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FG173_RS22405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FG173_RS22410	COG3117	lipopolysaccharide transmembrane transporter activity
FG173_RS22415	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FG173_RS22420	COG1137	ATPase activity
FG173_RS22425	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FG173_RS22440	COG1660	Displays ATPase and GTPase activities
FG173_RS22445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FG173_RS22450	COG4680	protein conserved in bacteria
FG173_RS22455	COG5499	transcription regulator containing HTH domain
FG173_RS22460	COG3711	transcriptional antiterminator
FG173_RS22460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FG173_RS22480	COG3964	amidohydrolase
FG173_RS22510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FG173_RS22520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FG173_RS22530	COG2207	Transcriptional regulator
FG173_RS22535	COG3783	Cytochrome b(562)
FG173_RS22540	COG0312	modulator of DNA gyrase
FG173_RS22555	COG3028	Belongs to the UPF0307 family
FG173_RS22560	COG2732	(Barnase) inhibitor
FG173_RS22570	COG1289	transmembrane transporter activity
FG173_RS22575	COG1566	PFAM secretion protein HlyD family protein
FG173_RS22585	COG0583	DNA-binding transcription factor activity
FG173_RS22610	COG2134	cdp-diacylglycerol pyrophosphatase
FG173_RS22620	COG0312	modulator of DNA gyrase
FG173_RS22625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FG173_RS22635	COG1530	ribonuclease E activity
FG173_RS22640	COG0424	maF-like protein
FG173_RS22645	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FG173_RS22650	COG1792	Involved in formation and maintenance of cell shape
FG173_RS22655	COG1077	Cell shape determining protein MreB Mrl
FG173_RS22660	COG2200	EAL domain
FG173_RS22660	COG2199	diguanylate cyclase activity
FG173_RS22665	COG0604	alcohol dehydrogenase
FG173_RS22670	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FG173_RS22675	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FG173_RS22680	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FG173_RS22685	COG0511	ligase activity, forming carbon-carbon bonds
FG173_RS22690	COG0439	Biotin carboxylase
FG173_RS22695	COG3924	membrane
FG173_RS22705	COG2264	protein methyltransferase activity
FG173_RS22735	COG1560	Kdo2-lipid A biosynthetic process
FG173_RS22780	COG1380	Effector of murein hydrolase LrgA
FG173_RS22785	COG0583	DNA-binding transcription factor activity
FG173_RS22790	COG0025	NhaP-type Na H and K H
FG173_RS22795	COG2252	PERMEase
FG173_RS22805	COG0625	glutathione transferase activity
FG173_RS22820	COG0583	DNA-binding transcription factor activity
FG173_RS22825	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS22850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FG173_RS22855	COG3713	MltA-interacting MipA family protein
FG173_RS22865	COG0110	maltose O-acetyltransferase activity
FG173_RS22870	COG2315	Protein conserved in bacteria
FG173_RS22875	COG0432	Pfam Uncharacterised protein family UPF0047
FG173_RS22880	COG1448	Aminotransferase
FG173_RS22885	COG1522	sequence-specific DNA binding
FG173_RS22905	COG0604	alcohol dehydrogenase
FG173_RS22915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FG173_RS22925	COG1595	DNA-templated transcription, initiation
FG173_RS22935	COG0735	belongs to the Fur family
FG173_RS22940	COG3237	CsbD-like
FG173_RS22945	COG0534	Mate efflux family protein
FG173_RS22950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FG173_RS22955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FG173_RS22960	COG2937	Belongs to the GPAT DAPAT family
FG173_RS22965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FG173_RS22970	COG3161	chorismate lyase activity
FG173_RS22975	COG0477	Major facilitator Superfamily
FG173_RS22980	COG1609	Transcriptional regulator
FG173_RS22995	COG4580	involved in the transport of maltose and maltodextrins
FG173_RS23005	COG0366	Alpha amylase catalytic
FG173_RS23010	COG2182	Extracellular solute-binding protein
FG173_RS23015	COG1175	transmembrane transport
FG173_RS23020	COG3833	ABC-type maltose transport systems, permease component
FG173_RS23025	COG3223	Belongs to the PsiE family
FG173_RS23035	COG0166	Belongs to the GPI family
FG173_RS23045	COG0527	aspartate kinase activity
FG173_RS23065	COG1283	sodium-dependent phosphate transmembrane transporter activity
FG173_RS23080	COG0395	ABC-type sugar transport system, permease component
FG173_RS23085	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FG173_RS23095	COG2188	Transcriptional regulator
FG173_RS23100	COG0646	methionine synthase
FG173_RS23100	COG1410	methionine synthase
FG173_RS23105	COG1414	Transcriptional regulator
FG173_RS23110	COG3265	gluconokinase activity
FG173_RS23120	COG0129	dihydroxy-acid dehydratase activity
FG173_RS23125	COG0800	Aldolase
FG173_RS23130	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FG173_RS23140	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FG173_RS23145	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FG173_RS23180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FG173_RS23185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FG173_RS23190	COG0009	L-threonylcarbamoyladenylate synthase
FG173_RS23195	COG0551	DNA topoisomerase type I activity
FG173_RS23200	COG2922	Belongs to the Smg family
FG173_RS23205	COG0758	DNA mediated transformation
FG173_RS23210	COG0242	peptide deformylase activity
FG173_RS23215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FG173_RS23220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FG173_RS23220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FG173_RS23225	COG0569	domain protein
FG173_RS23230	COG1970	mechanosensitive ion channel activity
FG173_RS23235	COG3036	rescue of stalled ribosome
FG173_RS23240	COG0789	Transcriptional regulator
FG173_RS23250	COG0203	ribosomal protein L17
FG173_RS23255	COG0202	RNA polymerase activity
FG173_RS23260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FG173_RS23265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FG173_RS23270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FG173_RS23275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FG173_RS23280	COG0201	protein transport
FG173_RS23290	COG1841	ribosomal large subunit assembly
FG173_RS23295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FG173_RS23300	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FG173_RS23305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FG173_RS23345	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FG173_RS23350	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FG173_RS23360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FG173_RS23370	COG0089	rRNA binding
FG173_RS23375	COG0088	Forms part of the polypeptide exit tunnel
FG173_RS23380	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FG173_RS23385	COG0051	transcription antitermination factor activity, RNA binding
FG173_RS23400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FG173_RS23410	COG0049	tRNA binding
FG173_RS23415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FG173_RS23420	COG2168	tRNA wobble position uridine thiolation
FG173_RS23425	COG2923	Belongs to the DsrF TusC family
FG173_RS23430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FG173_RS23435	COG2964	Protein conserved in bacteria
FG173_RS23440	COG0545	Peptidyl-prolyl cis-trans isomerase
FG173_RS23445	COG2900	Belongs to the SlyX family
FG173_RS23450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FG173_RS23455	COG1757	Na H antiporter
FG173_RS23460	COG1609	Transcriptional regulator
FG173_RS23465	COG1047	Peptidyl-prolyl cis-trans
FG173_RS23470	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FG173_RS23480	COG2249	NAD(P)H dehydrogenase (quinone) activity
FG173_RS23485	COG0488	(ABC) transporter
FG173_RS23490	COG2175	clavaminate synthase activity
FG173_RS23495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FG173_RS23505	COG4521	taurine ABC transporter
FG173_RS23520	COG0429	hydrolase of the alpha beta-hydrolase fold
FG173_RS23525	COG3089	Belongs to the UPF0270 family
FG173_RS23530	COG3954	Phosphoribulokinase
FG173_RS23535	COG1765	OsmC-like protein
FG173_RS23540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FG173_RS23545	COG1289	transmembrane transporter activity
FG173_RS23560	COG0433	COG0433 Predicted ATPase
FG173_RS23585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FG173_RS23595	COG1447	Phosphotransferase system cellobiose-specific component IIA
FG173_RS23600	COG1486	melibiose metabolic process
FG173_RS23605	COG1609	Transcriptional regulator
FG173_RS23610	COG0738	Major facilitator superfamily
FG173_RS23615	COG0402	S-adenosylhomocysteine deaminase activity
FG173_RS23625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FG173_RS23640	COG1648	precorrin-2 dehydrogenase activity
FG173_RS23640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FG173_RS23645	COG0180	Tryptophanyl-tRNA synthetase
FG173_RS23650	COG0546	phosphoglycolate phosphatase activity
FG173_RS23670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FG173_RS23675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FG173_RS23680	COG4796	Type ii and iii secretion system protein
FG173_RS23705	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FG173_RS23710	COG0494	nUDIX hydrolase
FG173_RS23720	COG1011	Hydrolase
FG173_RS23725	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FG173_RS23730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FG173_RS23745	COG1487	ribonuclease activity
FG173_RS23765	COG0484	heat shock protein binding
FG173_RS23770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FG173_RS23775	COG2183	response to ionizing radiation
FG173_RS23780	COG1918	ferrous iron import across plasma membrane
FG173_RS23805	COG1040	competence protein
FG173_RS23810	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FG173_RS23810	COG0316	Belongs to the HesB IscA family
FG173_RS23820	COG0058	SHG alpha-glucan phosphorylase activity
FG173_RS23825	COG2909	trisaccharide binding
FG173_RS23870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FG173_RS23875	COG0705	Rhomboid family
FG173_RS23880	COG1349	DNA-binding transcription factor activity
FG173_RS23885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FG173_RS23890	COG0058	SHG alpha-glucan phosphorylase activity
FG173_RS23895	COG0297	glycogen (starch) synthase activity
FG173_RS23900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FG173_RS23920	COG2095	MarC family integral membrane protein
FG173_RS23925	COG3265	gluconokinase activity
FG173_RS23930	COG2610	gluconate transmembrane transporter activity
FG173_RS23935	COG1609	Transcriptional regulator
FG173_RS23940	COG1741	Belongs to the pirin family
FG173_RS23945	COG1247	-acetyltransferase
FG173_RS23950	COG3191	aminopeptidase activity
FG173_RS23955	COG1082	Xylose isomerase domain protein TIM barrel
FG173_RS23960	COG1082	Xylose isomerase domain protein TIM barrel
FG173_RS23965	COG0673	inositol 2-dehydrogenase activity
FG173_RS23970	COG3962	Belongs to the TPP enzyme family
FG173_RS23975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FG173_RS23995	COG3718	enzyme involved in inositol metabolism
FG173_RS24005	COG0477	Major facilitator Superfamily
FG173_RS24005	COG2814	Major facilitator Superfamily
FG173_RS24015	COG0390	transport system, permease component
FG173_RS24020	COG4619	ABC transporter
FG173_RS24050	COG3188	usher protein
FG173_RS24055	COG3121	Chaperone
FG173_RS24075	COG2197	response regulator
FG173_RS24085	COG0697	spore germination
FG173_RS24130	COG0306	phosphate transporter
FG173_RS24140	COG1028	Short-chain dehydrogenase reductase Sdr
FG173_RS24150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FG173_RS24150	COG0475	glutathione-regulated potassium exporter activity
FG173_RS24160	COG0583	DNA-binding transcription factor activity
FG173_RS24165	COG0589	response to stress
FG173_RS24180	COG1129	ABC transporter
FG173_RS24185	COG1172	Belongs to the binding-protein-dependent transport system permease family
FG173_RS24190	COG1172	Belongs to the binding-protein-dependent transport system permease family
FG173_RS24240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FG173_RS24250	COG0784	Response regulator, receiver
FG173_RS24250	COG2205	protein histidine kinase activity
FG173_RS24275	COG5441	Belongs to the UPF0261 family
FG173_RS24280	COG3678	ATP-independent chaperone mediated protein folding
FG173_RS24285	COG5001	Diguanylate cyclase
FG173_RS24295	COG1295	ribonuclease BN
FG173_RS24305	COG2134	cdp-diacylglycerol pyrophosphatase
FG173_RS24315	COG2200	EAL domain
FG173_RS24320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FG173_RS24330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FG173_RS24350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FG173_RS24355	COG0129	dihydroxy-acid dehydratase activity
FG173_RS24360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FG173_RS24365	COG3978	acetolactate synthase activity
FG173_RS24380	COG2814	Major facilitator Superfamily
FG173_RS24390	COG3085	chromosome segregation
FG173_RS24395	COG0583	DNA-binding transcription factor activity
FG173_RS24435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FG173_RS24440	COG4206	TonB-dependent receptor
FG173_RS24445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FG173_RS24460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FG173_RS24470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FG173_RS24470	COG0678	peroxiredoxin activity
FG173_RS24475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FG173_RS24485	COG0165	Argininosuccinate lyase
FG173_RS24490	COG0137	argininosuccinate synthase activity
FG173_RS24495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FG173_RS24510	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FG173_RS24515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FG173_RS24520	COG0527	aspartate kinase activity
FG173_RS24520	COG0460	homoserine dehydrogenase
FG173_RS24525	COG0626	cystathionine gamma-synthase activity
FG173_RS24530	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FG173_RS24535	COG0254	rRNA binding
FG173_RS24540	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FG173_RS24550	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FG173_RS24555	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FG173_RS24560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FG173_RS24570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FG173_RS24580	COG3074	FtsZ-dependent cytokinesis
FG173_RS24600	COG1494	fructose-1,6-bisphosphatase
FG173_RS24610	COG2814	Major facilitator Superfamily
FG173_RS24635	COG0149	triose-phosphate isomerase activity
FG173_RS24640	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FG173_RS24645	COG0205	6-phosphofructokinase activity
FG173_RS24650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FG173_RS24655	COG3678	ATP-independent chaperone mediated protein folding
FG173_RS24660	COG0745	RESPONSE REGULATOR receiver
FG173_RS24665	COG2205	protein histidine kinase activity
FG173_RS24670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FG173_RS24685	COG1045	serine acetyltransferase
FG173_RS24700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FG173_RS24705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FG173_RS24710	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FG173_RS24715	COG4942	peptidase
FG173_RS24725	COG1063	alcohol dehydrogenase
FG173_RS24730	COG0156	8-amino-7-oxononanoate synthase activity
FG173_RS24735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FG173_RS24740	COG0859	PFAM glycosyl transferase family 9
FG173_RS24745	COG0859	PFAM glycosyl transferase family 9
FG173_RS24750	COG0438	transferase activity, transferring glycosyl groups
FG173_RS24755	COG3307	-O-antigen
FG173_RS24760	COG1442	glycosyl transferase family 8
FG173_RS24760	COG1216	Glycosyl transferase, family 2
FG173_RS24775	COG0859	PFAM glycosyl transferase family 9
FG173_RS24780	COG0438	transferase activity, transferring glycosyl groups
FG173_RS24785	COG0438	transferase activity, transferring glycosyl groups
FG173_RS24795	COG1519	Transferase
FG173_RS24815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FG173_RS24820	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FG173_RS24825	COG2003	Belongs to the UPF0758 family
FG173_RS24835	COG0756	dUTP diphosphatase activity
FG173_RS24840	COG1309	transcriptional regulator
FG173_RS24845	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FG173_RS24850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FG173_RS24865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FG173_RS24875	COG2860	membrane
FG173_RS24880	COG0194	GDP metabolic process
FG173_RS24885	COG1758	RNA polymerase activity
FG173_RS24890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FG173_RS24895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FG173_RS24905	COG0786	glutamate:sodium symporter activity
FG173_RS24910	COG2233	PERMEase
FG173_RS24920	COG0456	acetyltransferase
FG173_RS24925	COG1490	D-aminoacyl-tRNA deacylase activity
FG173_RS24930	COG1295	ribonuclease BN
FG173_RS24935	COG1011	Hydrolase
FG173_RS24940	COG1217	gtp-binding protein TYPA
FG173_RS24945	COG0174	glutamine synthetase
FG173_RS24965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FG173_RS24975	COG3078	GTPase activator activity
FG173_RS24985	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FG173_RS24990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FG173_RS24990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FG173_RS24995	COG0204	Acyl-transferase
FG173_RS25000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FG173_RS25005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FG173_RS25010	COG3084	Protein conserved in bacteria
FG173_RS25015	COG0746	molybdenum cofactor guanylyltransferase activity
FG173_RS25020	COG1763	Mo-molybdopterin cofactor biosynthetic process
FG173_RS25045	COG2186	Transcriptional regulator
FG173_RS25050	COG0477	Major facilitator Superfamily
FG173_RS25055	COG1609	Transcriptional regulator
FG173_RS25060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FG173_RS25070	COG1172	Belongs to the binding-protein-dependent transport system permease family
FG173_RS25080	COG1869	D-ribose catabolic process
FG173_RS25085	COG3158	transport of potassium into the cell
FG173_RS25090	COG0714	Associated with various cellular activities
FG173_RS25095	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FG173_RS25100	COG2502	aspartate--ammonia ligase
FG173_RS25105	COG1522	sequence-specific DNA binding
FG173_RS25110	COG0716	FMN binding
FG173_RS25120	COG0357	Ribosomal RNA small subunit methyltransferase G
FG173_RS25125	COG3312	ion transport
FG173_RS25140	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FG173_RS25145	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FG173_RS25150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FG173_RS25155	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FG173_RS25160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FG173_RS25165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FG173_RS25170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FG173_RS25185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FG173_RS25190	COG0573	inorganic phosphate transmembrane transporter activity
FG173_RS25195	COG0581	inorganic phosphate transmembrane transporter activity
FG173_RS25205	COG0704	Plays a role in the regulation of phosphate uptake
FG173_RS25210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FG173_RS25215	COG0765	amino acid transport
FG173_RS25220	COG0765	amino acid transport
FG173_RS25230	COG0494	nUDIX hydrolase
FG173_RS25235	COG2252	PERMEase
FG173_RS25245	COG0431	NADPH-dependent FMN reductase
FG173_RS25250	COG2091	lysine biosynthetic process via aminoadipic acid
FG173_RS25270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FG173_RS25275	COG0706	membrane insertase activity
FG173_RS25280	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FG173_RS25285	COG0594	ribonuclease P activity