locus-tag	class	description
SWP_RS00005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SWP_RS00010	COG1115	amino acid carrier protein
SWP_RS00020	COG3214	Protein conserved in bacteria
SWP_RS00025	COG0653	protein targeting
SWP_RS00050	COG1643	Atp-dependent helicase
SWP_RS00055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SWP_RS00060	COG0706	membrane insertase activity
SWP_RS00065	COG0594	ribonuclease P activity
SWP_RS00070	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SWP_RS00075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SWP_RS00085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SWP_RS00090	COG0187	DNA topoisomerase II activity
SWP_RS00095	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SWP_RS00100	COG0751	glycine-tRNA ligase activity
SWP_RS00105	COG0752	glycyl-tRNA synthetase alpha subunit
SWP_RS00110	COG2818	Glycosylase
SWP_RS00115	COG1506	peptidase
SWP_RS00115	COG0823	Involved in the tonB-independent uptake of proteins
SWP_RS00115	COG4946	Tricorn protease homolog
SWP_RS00125	COG0425	Belongs to the sulfur carrier protein TusA family
SWP_RS00130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SWP_RS00160	COG0741	lytic transglycosylase activity
SWP_RS00165	COG0183	Belongs to the thiolase family
SWP_RS00170	COG1250	3-hydroxyacyl-CoA dehydrogenase
SWP_RS00170	COG1024	Enoyl-CoA hydratase
SWP_RS00195	COG0318	PFAM AMP-dependent synthetase and ligase
SWP_RS00200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SWP_RS00200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SWP_RS00200	COG3321	synthase
SWP_RS00200	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SWP_RS00225	COG0006	proline dipeptidase activity
SWP_RS00230	COG1739	Uncharacterized protein family UPF0029
SWP_RS00235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SWP_RS00240	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
SWP_RS00245	COG0640	Transcriptional regulator
SWP_RS00250	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
SWP_RS00255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SWP_RS00260	COG0569	domain protein
SWP_RS00265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SWP_RS00265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SWP_RS00270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SWP_RS00275	COG0242	peptide deformylase activity
SWP_RS00285	COG0758	DNA mediated transformation
SWP_RS00290	COG2922	Belongs to the Smg family
SWP_RS00295	COG3291	Pkd domain containing protein
SWP_RS00300	COG0551	DNA topoisomerase type I activity
SWP_RS00305	COG0009	L-threonylcarbamoyladenylate synthase
SWP_RS00310	COG0408	coproporphyrinogen oxidase activity
SWP_RS00315	COG2346	COG2346, Truncated hemoglobins
SWP_RS00320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SWP_RS00330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SWP_RS00360	COG1959	2 iron, 2 sulfur cluster binding
SWP_RS00365	COG2861	carbohydrate metabolic process
SWP_RS00370	COG0793	Belongs to the peptidase S41A family
SWP_RS00375	COG4942	peptidase
SWP_RS00380	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SWP_RS00385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SWP_RS00390	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
SWP_RS00395	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SWP_RS00400	COG2081	HI0933 family
SWP_RS00405	COG4774	siderophore transport
SWP_RS00425	COG2814	Major facilitator Superfamily
SWP_RS00435	COG0019	diaminopimelate decarboxylase activity
SWP_RS00450	COG0697	spore germination
SWP_RS00460	COG3706	GGDEF domain
SWP_RS00480	COG0791	NLP P60 protein
SWP_RS00485	COG0521	Mo-molybdopterin cofactor biosynthetic process
SWP_RS00495	COG2207	Transcriptional regulator
SWP_RS00495	COG1917	Cupin 2, conserved barrel domain protein
SWP_RS00505	COG1668	transmembrane transport
SWP_RS00510	COG4555	ABC transporter
SWP_RS00520	COG2188	Transcriptional regulator
SWP_RS00525	COG1131	(ABC) transporter
SWP_RS00535	COG1022	Amp-dependent synthetase and ligase
SWP_RS00575	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SWP_RS00600	COG1136	(ABC) transporter
SWP_RS00600	COG0577	efflux transmembrane transporter activity
SWP_RS00610	COG1228	amidohydrolase
SWP_RS00615	COG2188	Transcriptional regulator
SWP_RS00620	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SWP_RS00625	COG2986	histidine ammonia-lyase
SWP_RS00655	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SWP_RS00675	COG0668	transmembrane transport
SWP_RS00690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SWP_RS00700	COG3220	belongs to the UPF0276 family
SWP_RS00710	COG1595	DNA-templated transcription, initiation
SWP_RS00725	COG2801	Transposase and inactivated derivatives
SWP_RS00730	COG2963	transposase activity
SWP_RS00760	COG1629	transport
SWP_RS00760	COG4774	siderophore transport
SWP_RS00780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SWP_RS00785	COG0303	'Molybdopterin
SWP_RS00790	COG1528	Iron-storage protein
SWP_RS00800	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SWP_RS00805	COG1770	oligopeptidase
SWP_RS00815	COG0730	response to heat
SWP_RS00825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SWP_RS00855	COG1476	TRANSCRIPTIONal
SWP_RS00865	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SWP_RS00870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SWP_RS00875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SWP_RS00890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SWP_RS00895	COG1459	type II secretion system
SWP_RS00900	COG2165	general secretion pathway protein
SWP_RS00910	COG2165	general secretion pathway protein
SWP_RS00915	COG4795	General secretion pathway protein
SWP_RS00920	COG3156	type II secretion system protein K
SWP_RS00940	COG1011	Hydrolase
SWP_RS00945	COG0494	nUDIX hydrolase
SWP_RS00950	COG1218	3'(2'),5'-bisphosphate nucleotidase
SWP_RS00955	COG0477	Major facilitator Superfamily
SWP_RS00960	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SWP_RS00980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SWP_RS00985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SWP_RS01010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SWP_RS01020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SWP_RS01025	COG1328	CTP reductase activity
SWP_RS01035	COG0604	alcohol dehydrogenase
SWP_RS01050	COG1053	succinate dehydrogenase
SWP_RS01075	COG0583	DNA-binding transcription factor activity
SWP_RS01090	COG0306	phosphate transporter
SWP_RS01115	COG2954	triphosphatase activity
SWP_RS01130	COG2801	Transposase and inactivated derivatives
SWP_RS01135	COG2205	protein histidine kinase activity
SWP_RS01140	COG0745	RESPONSE REGULATOR receiver
SWP_RS01145	COG3678	ATP-independent chaperone mediated protein folding
SWP_RS01170	COG3852	Histidine kinase
SWP_RS01200	COG1979	alcohol dehydrogenase
SWP_RS01205	COG1309	transcriptional regulator
SWP_RS01210	COG1522	sequence-specific DNA binding
SWP_RS01220	COG3844	kynureninase activity
SWP_RS01245	COG1301	dicarboxylic acid transport
SWP_RS01255	COG0174	glutamine synthetase
SWP_RS01260	COG1217	gtp-binding protein TYPA
SWP_RS01285	COG2311	Membrane
SWP_RS01290	COG0348	domain, Protein
SWP_RS01305	COG1295	ribonuclease BN
SWP_RS01320	COG1490	D-aminoacyl-tRNA deacylase activity
SWP_RS01325	COG0456	acetyltransferase
SWP_RS01335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SWP_RS01340	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS01350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SWP_RS01380	COG2986	histidine ammonia-lyase
SWP_RS01390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SWP_RS01395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SWP_RS01405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SWP_RS01410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SWP_RS01415	COG0204	Acyl-transferase
SWP_RS01415	COG0318	PFAM AMP-dependent synthetase and ligase
SWP_RS01430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SWP_RS01435	COG2197	response regulator
SWP_RS01440	COG4585	Histidine kinase
SWP_RS01455	COG1022	Amp-dependent synthetase and ligase
SWP_RS01460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SWP_RS01470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SWP_RS01475	COG1758	RNA polymerase activity
SWP_RS01500	COG0427	acetyl-CoA hydrolase
SWP_RS01520	COG2267	carboxylic ester hydrolase activity
SWP_RS01545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SWP_RS01555	COG0204	Acyl-transferase
SWP_RS01560	COG0204	Acyl-transferase
SWP_RS01565	COG0606	chelatase, subunit chli
SWP_RS01595	COG2194	sulfuric ester hydrolase activity
SWP_RS01620	COG0583	DNA-binding transcription factor activity
SWP_RS01625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SWP_RS01635	COG3978	acetolactate synthase activity
SWP_RS01645	COG0129	dihydroxy-acid dehydratase activity
SWP_RS01650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SWP_RS01660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SWP_RS01680	COG1309	transcriptional regulator
SWP_RS01690	COG0733	neurotransmitter:sodium symporter activity
SWP_RS01695	COG1522	sequence-specific DNA binding
SWP_RS01700	COG0671	phosphoesterase, PA-phosphatase related
SWP_RS01715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SWP_RS01720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS01725	COG1309	transcriptional regulator
SWP_RS01760	COG3713	MltA-interacting MipA family protein
SWP_RS01770	COG2205	protein histidine kinase activity
SWP_RS01775	COG0745	RESPONSE REGULATOR receiver
SWP_RS01805	COG1538	Outer membrane efflux protein
SWP_RS01810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS01840	COG2959	enzyme of heme biosynthesis
SWP_RS01850	COG0181	hydroxymethylbilane synthase activity
SWP_RS01855	COG3072	Adenylate cyclase
SWP_RS01865	COG0019	diaminopimelate decarboxylase activity
SWP_RS01870	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SWP_RS01880	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SWP_RS01885	COG1011	Hydrolase
SWP_RS01930	COG0519	Catalyzes the synthesis of GMP from XMP
SWP_RS01945	COG0174	glutamine synthetase
SWP_RS01950	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
SWP_RS01955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SWP_RS01960	COG2264	protein methyltransferase activity
SWP_RS01975	COG1053	succinate dehydrogenase
SWP_RS01980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SWP_RS01990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SWP_RS01995	COG3118	belongs to the thioredoxin family
SWP_RS02000	COG0513	Belongs to the DEAD box helicase family
SWP_RS02005	COG0248	Ppx GppA phosphatase
SWP_RS02030	COG4251	negative regulation of phosphorylation
SWP_RS02030	COG3706	GGDEF domain
SWP_RS02030	COG2203	Gaf domain
SWP_RS02030	COG5001	Diguanylate cyclase
SWP_RS02045	COG0805	protein transport
SWP_RS02050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SWP_RS02055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SWP_RS02060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SWP_RS02070	COG2226	methyltransferase
SWP_RS02075	COG0010	Belongs to the arginase family
SWP_RS02085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SWP_RS02095	COG0671	phosphoesterase, PA-phosphatase related
SWP_RS02115	COG0813	purine-nucleoside phosphorylase activity
SWP_RS02125	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SWP_RS02130	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SWP_RS02190	COG0018	arginyl-trna synthetase
SWP_RS02195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SWP_RS02205	COG0254	rRNA binding
SWP_RS02215	COG0281	malic enzyme
SWP_RS02250	COG3267	Type II secretory pathway component ExeA
SWP_RS02250	COG3409	Peptidoglycan-binding domain 1 protein
SWP_RS02260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SWP_RS02265	COG1459	type II secretion system
SWP_RS02275	COG2165	general secretion pathway protein
SWP_RS02280	COG2165	general secretion pathway protein
SWP_RS02315	COG1077	Cell shape determining protein MreB Mrl
SWP_RS02320	COG1792	Involved in formation and maintenance of cell shape
SWP_RS02325	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
SWP_RS02335	COG1530	ribonuclease E activity
SWP_RS02340	COG3164	Protein of unknown function
SWP_RS02345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SWP_RS02350	COG0312	modulator of DNA gyrase
SWP_RS02360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS02385	COG0312	modulator of DNA gyrase
SWP_RS02395	COG0640	Transcriptional regulator
SWP_RS02400	COG0798	PFAM Bile acid sodium symporter
SWP_RS02405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SWP_RS02415	COG1115	amino acid carrier protein
SWP_RS02435	COG0776	regulation of translation
SWP_RS02470	COG5001	Diguanylate cyclase
SWP_RS02470	COG3300	MHYT domain
SWP_RS02490	COG4989	oxidoreductase activity
SWP_RS02495	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SWP_RS02500	COG0668	transmembrane transport
SWP_RS02530	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
SWP_RS02535	COG3706	GGDEF domain
SWP_RS02540	COG2201	protein-glutamate methylesterase activity
SWP_RS02545	COG1024	Enoyl-CoA hydratase
SWP_RS02560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SWP_RS02565	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SWP_RS02570	COG3850	Histidine kinase
SWP_RS02570	COG2205	protein histidine kinase activity
SWP_RS02570	COG3437	response regulator, receiver
SWP_RS02570	COG4999	Histidine kinase
SWP_RS02605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS02610	COG0583	DNA-binding transcription factor activity
SWP_RS02620	COG0534	Mate efflux family protein
SWP_RS02625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SWP_RS02630	COG0459	protein refolding
SWP_RS02655	COG0671	phosphoesterase, PA-phosphatase related
SWP_RS02690	COG3961	Belongs to the TPP enzyme family
SWP_RS02695	COG0583	DNA-binding transcription factor activity
SWP_RS02735	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
SWP_RS02740	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
SWP_RS02745	COG1342	Belongs to the UPF0251 family
SWP_RS02760	COG0697	spore germination
SWP_RS02765	COG1846	Transcriptional regulator
SWP_RS02785	COG0640	Transcriptional regulator
SWP_RS02815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SWP_RS02820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SWP_RS02830	COG2203	Gaf domain
SWP_RS02830	COG5001	Diguanylate cyclase
SWP_RS02830	COG4251	negative regulation of phosphorylation
SWP_RS02830	COG3706	GGDEF domain
SWP_RS02845	COG4249	Peptidase C14 caspase catalytic subunit p20
SWP_RS02845	COG2319	Wd-40 repeat
SWP_RS02855	COG3585	molybdate ion transport
SWP_RS02865	COG0644	oxidoreductase
SWP_RS02915	COG5002	protein histidine kinase activity
SWP_RS02915	COG3850	Histidine kinase
SWP_RS02920	COG0745	RESPONSE REGULATOR receiver
SWP_RS02925	COG0463	Glycosyl transferase, family 2
SWP_RS02960	COG2885	chlorophyll binding
SWP_RS02970	COG2239	Acts as a magnesium transporter
SWP_RS02975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SWP_RS02980	COG1660	Displays ATPase and GTPase activities
SWP_RS02985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SWP_RS02995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SWP_RS03000	COG1137	ATPase activity
SWP_RS03015	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SWP_RS03020	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SWP_RS03020	COG0517	IMP dehydrogenase activity
SWP_RS03030	COG1127	ABC transporter
SWP_RS03035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SWP_RS03040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SWP_RS03045	COG2854	intermembrane phospholipid transfer
SWP_RS03050	COG3113	response to antibiotic
SWP_RS03055	COG5007	Belongs to the BolA IbaG family
SWP_RS03060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SWP_RS03080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SWP_RS03085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SWP_RS03095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SWP_RS03100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SWP_RS03105	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SWP_RS03110	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
SWP_RS03115	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SWP_RS03120	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SWP_RS03125	COG0557	exoribonuclease II activity
SWP_RS03130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SWP_RS03135	COG1505	serine-type exopeptidase activity
SWP_RS03145	COG0360	Binds together with S18 to 16S ribosomal RNA
SWP_RS03150	COG2965	DNA replication, synthesis of RNA primer
SWP_RS03155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SWP_RS03160	COG0359	binds to the 23S rRNA
SWP_RS03170	COG4990	cell redox homeostasis
SWP_RS03170	COG3591	Belongs to the peptidase S1B family
SWP_RS03180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SWP_RS03200	COG0583	DNA-binding transcription factor activity
SWP_RS03205	COG0243	molybdopterin cofactor binding
SWP_RS03210	COG0437	4 iron, 4 sulfur cluster binding
SWP_RS03215	COG3381	protein complex oligomerization
SWP_RS03230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SWP_RS03245	COG1024	Enoyl-CoA hydratase
SWP_RS03270	COG0488	(ABC) transporter
SWP_RS03275	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
SWP_RS03285	COG0513	Belongs to the DEAD box helicase family
SWP_RS03295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SWP_RS03305	COG1012	belongs to the aldehyde dehydrogenase family
SWP_RS03340	COG3954	Phosphoribulokinase
SWP_RS03350	COG0429	hydrolase of the alpha beta-hydrolase fold
SWP_RS03360	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SWP_RS03365	COG1538	Outer membrane efflux protein
SWP_RS03370	COG0494	nUDIX hydrolase
SWP_RS03375	COG3151	Protein conserved in bacteria
SWP_RS03385	COG3150	esterase
SWP_RS03390	COG0187	DNA topoisomerase II activity
SWP_RS03420	COG0584	glycerophosphoryl diester phosphodiesterase
SWP_RS03425	COG3264	Mechanosensitive ion channel
SWP_RS03425	COG1511	domain protein
SWP_RS03430	COG0697	spore germination
SWP_RS03435	COG0688	phosphatidylethanolamine metabolic process
SWP_RS03440	COG1162	GTPase activity
SWP_RS03445	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SWP_RS03475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SWP_RS03475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SWP_RS03480	COG0802	atpase or kinase
SWP_RS03485	COG0860	N-Acetylmuramoyl-L-alanine amidase
SWP_RS03490	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SWP_RS03495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SWP_RS03500	COG1923	regulation of RNA biosynthetic process
SWP_RS03505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SWP_RS03510	COG0330	HflC and HflK could
SWP_RS03515	COG0330	HflC and HflK could
SWP_RS03520	COG0723	plastoquinol--plastocyanin reductase activity
SWP_RS03525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SWP_RS03530	COG2857	Cytochrome c1
SWP_RS03535	COG0625	glutathione transferase activity
SWP_RS03540	COG2969	positive regulation of protein catabolic process
SWP_RS03545	COG0512	Glutamine amidotransferase of anthranilate synthase
SWP_RS03555	COG0513	Belongs to the DEAD box helicase family
SWP_RS03570	COG4988	ABC transporter
SWP_RS03575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SWP_RS03590	COG4991	sh3 domain protein
SWP_RS03595	COG0306	phosphate transporter
SWP_RS03600	COG1392	Phosphate transport regulator
SWP_RS03605	COG3025	triphosphatase activity
SWP_RS03610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SWP_RS03630	COG3789	protein conserved in bacteria
SWP_RS03635	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SWP_RS03650	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SWP_RS03680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SWP_RS03685	COG0612	Peptidase, M16
SWP_RS03695	COG3604	Transcriptional regulator
SWP_RS03705	COG1560	Kdo2-lipid A biosynthetic process
SWP_RS03755	COG0705	Rhomboid family
SWP_RS03785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SWP_RS03790	COG0175	sulfate reduction
SWP_RS03815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SWP_RS03825	COG2354	Protein conserved in bacteria
SWP_RS03870	COG2900	Belongs to the SlyX family
SWP_RS03875	COG0545	Peptidyl-prolyl cis-trans isomerase
SWP_RS03885	COG3313	Fe-S protein
SWP_RS03895	COG0745	RESPONSE REGULATOR receiver
SWP_RS03920	COG0589	response to stress
SWP_RS03945	COG0431	NADPH-dependent FMN reductase
SWP_RS03970	COG1584	GPR1 FUN34 yaaH family protein
SWP_RS03985	COG1346	cytolysis
SWP_RS04000	COG0525	valine-tRNA ligase activity
SWP_RS04005	COG2927	DNA polymerase III (CHI subunit)
SWP_RS04020	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
SWP_RS04025	COG3079	Belongs to the UPF0149 family
SWP_RS04030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SWP_RS04035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SWP_RS04040	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SWP_RS04045	COG0509	glycine decarboxylation via glycine cleavage system
SWP_RS04050	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SWP_RS04050	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SWP_RS04065	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
SWP_RS04095	COG0804	urea catabolic process
SWP_RS04110	COG0651	ATP synthesis coupled electron transport
SWP_RS04120	COG0651	ATP synthesis coupled electron transport
SWP_RS04125	COG0651	ATP synthesis coupled electron transport
SWP_RS04130	COG1006	Multisubunit Na H antiporter MnhC subunit
SWP_RS04140	COG1320	monovalent cation:proton antiporter activity
SWP_RS04165	COG1757	Na H antiporter
SWP_RS04175	COG2366	antibiotic biosynthetic process
SWP_RS04260	COG0583	DNA-binding transcription factor activity
SWP_RS04280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SWP_RS04290	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SWP_RS04295	COG1902	pentaerythritol trinitrate reductase activity
SWP_RS04305	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SWP_RS04320	COG3321	synthase
SWP_RS04320	COG0604	alcohol dehydrogenase
SWP_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS04345	COG0583	DNA-binding transcription factor activity
SWP_RS04355	COG2072	flavoprotein involved in K transport
SWP_RS04370	COG1120	ATPase activity
SWP_RS04375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SWP_RS04380	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SWP_RS04385	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SWP_RS04395	COG1492	cobalamin metabolic process
SWP_RS04400	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SWP_RS04530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SWP_RS04535	COG2814	Major facilitator Superfamily
SWP_RS04575	COG0641	radical SAM
SWP_RS04595	COG1136	(ABC) transporter
SWP_RS04605	COG0577	efflux transmembrane transporter activity
SWP_RS04605	COG1136	(ABC) transporter
SWP_RS04610	COG2204	response regulator
SWP_RS04615	COG3852	Histidine kinase
SWP_RS04630	COG1538	Outer membrane efflux protein
SWP_RS04640	COG1309	transcriptional regulator
SWP_RS04655	COG0589	response to stress
SWP_RS04705	COG0745	RESPONSE REGULATOR receiver
SWP_RS04715	COG2205	protein histidine kinase activity
SWP_RS04715	COG0784	Response regulator, receiver
SWP_RS04715	COG2198	Histidine kinase
SWP_RS04730	COG1278	Cold shock
SWP_RS04755	COG1902	pentaerythritol trinitrate reductase activity
SWP_RS04760	COG0346	lactoylglutathione lyase activity
SWP_RS04795	COG2205	protein histidine kinase activity
SWP_RS04795	COG0784	Response regulator, receiver
SWP_RS04815	COG3590	peptidase
SWP_RS04855	COG0330	HflC and HflK could
SWP_RS04875	COG1966	Carbon starvation protein
SWP_RS04890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SWP_RS04895	COG0358	DNA primase activity
SWP_RS04900	COG1610	YqeY-like protein
SWP_RS04905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SWP_RS04910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SWP_RS04915	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SWP_RS04920	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SWP_RS04930	COG1968	undecaprenyl-diphosphatase activity
SWP_RS04935	COG2226	methyltransferase
SWP_RS04940	COG1376	ErfK ybiS ycfS ynhG family protein
SWP_RS04940	COG1388	LysM domain
SWP_RS04950	COG0617	tRNA 3'-terminal CCA addition
SWP_RS04955	COG3267	Type II secretory pathway component ExeA
SWP_RS04955	COG3409	Peptidoglycan-binding domain 1 protein
SWP_RS04975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SWP_RS04980	COG0540	Belongs to the ATCase OTCase family
SWP_RS04990	COG1477	protein flavinylation
SWP_RS04995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SWP_RS05020	COG3094	Invasion gene expression up-regulator, SirB
SWP_RS05035	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SWP_RS05040	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SWP_RS05055	COG0733	neurotransmitter:sodium symporter activity
SWP_RS05060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SWP_RS05070	COG1666	GTP binding
SWP_RS05075	COG2211	Major facilitator Superfamily
SWP_RS05120	COG2813	Specifically methylates the guanine in position
SWP_RS05135	COG0271	Belongs to the BolA IbaG family
SWP_RS05140	COG1854	S-ribosylhomocysteine lyase activity
SWP_RS05145	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SWP_RS05150	COG1805	sodium ion transport
SWP_RS05155	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SWP_RS05160	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SWP_RS05165	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SWP_RS05170	COG2871	sodium ion transport
SWP_RS05175	COG1477	protein flavinylation
SWP_RS05180	COG2991	Protein conserved in bacteria
SWP_RS05190	COG2193	ferroxidase activity
SWP_RS05205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SWP_RS05210	COG2195	Cleaves the N-terminal amino acid of tripeptides
SWP_RS05215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SWP_RS05245	COG2252	PERMEase
SWP_RS05250	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SWP_RS05255	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SWP_RS05265	COG0697	spore germination
SWP_RS05270	COG0443	Heat shock 70 kDa protein
SWP_RS05275	COG0484	heat shock protein binding
SWP_RS05285	COG0545	Peptidyl-prolyl cis-trans isomerase
SWP_RS05290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SWP_RS05295	COG0505	Belongs to the CarA family
SWP_RS05300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SWP_RS05315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SWP_RS05320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SWP_RS05325	COG1534	Rna-binding protein
SWP_RS05330	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
SWP_RS05340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SWP_RS05345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SWP_RS05350	COG0149	triose-phosphate isomerase activity
SWP_RS05355	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SWP_RS05370	COG0779	Required for maturation of 30S ribosomal subunits
SWP_RS05375	COG0195	Participates in both transcription termination and antitermination
SWP_RS05380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SWP_RS05385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SWP_RS05390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SWP_RS05395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SWP_RS05405	COG1185	polyribonucleotide nucleotidyltransferase activity
SWP_RS05415	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SWP_RS05420	COG0084	hydrolase, TatD family'
SWP_RS05425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SWP_RS05435	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SWP_RS05440	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SWP_RS05450	COG0813	purine-nucleoside phosphorylase activity
SWP_RS05460	COG0560	Phosphoserine phosphatase
SWP_RS05485	COG0437	4 iron, 4 sulfur cluster binding
SWP_RS05490	COG3301	Polysulphide reductase, NrfD
SWP_RS05500	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SWP_RS05520	COG0513	Belongs to the DEAD box helicase family
SWP_RS05560	COG2252	PERMEase
SWP_RS05575	COG3314	Sporulation integral membrane protein YlbJ
SWP_RS05580	COG0840	transmembrane signaling receptor activity
SWP_RS05590	COG0826	peptidase U32
SWP_RS05595	COG0826	peptidase U32
SWP_RS05600	COG3154	lipid carrier protein
SWP_RS05605	COG2974	May be involved in recombination
SWP_RS05615	COG0745	RESPONSE REGULATOR receiver
SWP_RS05620	COG5002	protein histidine kinase activity
SWP_RS05640	COG0386	Belongs to the glutathione peroxidase family
SWP_RS05670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SWP_RS05670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SWP_RS05690	COG1671	Belongs to the UPF0178 family
SWP_RS05700	COG0668	transmembrane transport
SWP_RS05705	COG2860	membrane
SWP_RS05710	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
SWP_RS05720	COG1785	Belongs to the alkaline phosphatase family
SWP_RS05725	COG1785	Belongs to the alkaline phosphatase family
SWP_RS05740	COG1252	NADH dehydrogenase
SWP_RS05750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS05795	COG1454	alcohol dehydrogenase
SWP_RS05800	COG1640	4-alpha-glucanotransferase
SWP_RS05815	COG0058	SHG alpha-glucan phosphorylase activity
SWP_RS05820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SWP_RS05870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SWP_RS05875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS05895	COG0488	(ABC) transporter
SWP_RS05905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SWP_RS05910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SWP_RS05915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SWP_RS05915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SWP_RS05930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SWP_RS05935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SWP_RS05945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SWP_RS05950	COG0497	DNA recombination
SWP_RS05960	COG0583	DNA-binding transcription factor activity
SWP_RS05975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SWP_RS05980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SWP_RS05985	COG3956	TIGRFAM MazG family protein
SWP_RS05990	COG0504	CTP synthase activity
SWP_RS05995	COG0148	phosphopyruvate hydratase activity
SWP_RS06000	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
SWP_RS06005	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SWP_RS06010	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SWP_RS06015	COG0585	pseudouridine synthase activity
SWP_RS06020	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SWP_RS06025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SWP_RS06030	COG1388	LysM domain
SWP_RS06030	COG4942	peptidase
SWP_RS06040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SWP_RS06045	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SWP_RS06050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SWP_RS06055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SWP_RS06095	COG3119	arylsulfatase activity
SWP_RS06100	COG0714	Associated with various cellular activities
SWP_RS06130	COG3630	sodium ion export across plasma membrane
SWP_RS06135	COG0511	ligase activity, forming carbon-carbon bonds
SWP_RS06135	COG5016	pyruvate
SWP_RS06140	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SWP_RS06150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS06165	COG1301	dicarboxylic acid transport
SWP_RS06170	COG0612	Peptidase, M16
SWP_RS06175	COG2918	glutathione biosynthetic process
SWP_RS06195	COG3706	GGDEF domain
SWP_RS06200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SWP_RS06220	COG0793	Belongs to the peptidase S41A family
SWP_RS06220	COG4946	Tricorn protease homolog
SWP_RS06240	COG3437	response regulator, receiver
SWP_RS06265	COG0438	transferase activity, transferring glycosyl groups
SWP_RS06290	COG0778	Nitroreductase
SWP_RS06295	COG2824	Alkylphosphonate utilization operon protein PhnA
SWP_RS06305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SWP_RS06330	COG0339	signal peptide processing
SWP_RS06335	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SWP_RS06340	COG2867	negative regulation of translational initiation
SWP_RS06345	COG2914	Belongs to the UPF0125 (RnfH) family
SWP_RS06350	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SWP_RS06355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SWP_RS06370	COG3228	Belongs to the MtfA family
SWP_RS06385	COG3530	Putative quorum-sensing-regulated virulence factor
SWP_RS06405	COG0737	Belongs to the 5'-nucleotidase family
SWP_RS06410	COG1253	flavin adenine dinucleotide binding
SWP_RS06430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SWP_RS06435	COG0124	histidyl-tRNA synthetase
SWP_RS06440	COG2976	Protein conserved in bacteria
SWP_RS06445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SWP_RS06450	COG1160	GTP binding
SWP_RS06465	COG3620	sequence-specific DNA binding
SWP_RS06490	COG1570	exodeoxyribonuclease VII activity
SWP_RS06495	COG0516	GMP reductase activity
SWP_RS06495	COG0517	IMP dehydrogenase activity
SWP_RS06500	COG0519	Catalyzes the synthesis of GMP from XMP
SWP_RS06500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SWP_RS06510	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SWP_RS06525	COG1294	oxidase, subunit
SWP_RS06605	COG3291	Pkd domain containing protein
SWP_RS06645	COG0784	Response regulator, receiver
SWP_RS06645	COG0835	chemotaxis
SWP_RS06650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SWP_RS06655	COG1815	bacterial-type flagellum-dependent cell motility
SWP_RS06660	COG1558	bacterial-type flagellum-dependent cell motility
SWP_RS06670	COG1749	Flagellar hook protein flgE
SWP_RS06675	COG4787	bacterial-type flagellum-dependent cell motility
SWP_RS06690	COG1706	bacterial-type flagellum-dependent cell motility
SWP_RS06695	COG1705	Flagellar rod assembly protein muramidase FlgJ
SWP_RS06695	COG3951	Flagellar rod assembly protein muramidase FlgJ
SWP_RS06720	COG1334	flagellar protein FlaG
SWP_RS06735	COG1516	flagellar protein fliS
SWP_RS06755	COG1677	Flagellar hook-basal body complex protein FliE
SWP_RS06765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SWP_RS06780	COG2882	bacterial-type flagellum organization
SWP_RS06815	COG1987	bacterial-type flagellum assembly
SWP_RS06825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SWP_RS06855	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
SWP_RS06860	COG2198	Histidine kinase
SWP_RS06860	COG0643	Histidine kinase
SWP_RS06860	COG0784	Response regulator, receiver
SWP_RS06875	COG1192	Involved in chromosome partitioning
SWP_RS06885	COG0835	chemotaxis
SWP_RS06915	COG3104	oligopeptide transport
SWP_RS06935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SWP_RS06945	COG1216	Glycosyl transferase, family 2
SWP_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS06995	COG1596	polysaccharide export
SWP_RS07010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SWP_RS07035	COG0438	transferase activity, transferring glycosyl groups
SWP_RS07055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SWP_RS07060	COG0175	sulfate reduction
SWP_RS07065	COG2895	sulfate adenylyltransferase (ATP) activity
SWP_RS07070	COG3273	potassium ion transport
SWP_RS07070	COG0471	metal ion transport
SWP_RS07075	COG0529	Catalyzes the synthesis of activated sulfate
SWP_RS07100	COG1088	dTDP-glucose 4,6-dehydratase activity
SWP_RS07110	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SWP_RS07125	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SWP_RS07130	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SWP_RS07135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SWP_RS07145	COG2244	polysaccharide biosynthetic process
SWP_RS07165	COG1366	Belongs to the anti-sigma-factor antagonist family
SWP_RS07175	COG0745	RESPONSE REGULATOR receiver
SWP_RS07190	COG2204	response regulator
SWP_RS07195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SWP_RS07210	COG1472	Belongs to the glycosyl hydrolase 3 family
SWP_RS07245	COG1609	Transcriptional regulator
SWP_RS07250	COG2211	Major facilitator Superfamily
SWP_RS07280	COG1940	carbohydrate kinase activity
SWP_RS07285	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SWP_RS07300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SWP_RS07300	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
SWP_RS07305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SWP_RS07310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SWP_RS07320	COG2154	pterin-4-alpha-carbinolamine dehydratase
SWP_RS07335	COG0625	glutathione transferase activity
SWP_RS07340	COG0583	DNA-binding transcription factor activity
SWP_RS07345	COG2814	Major facilitator Superfamily
SWP_RS07375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SWP_RS07420	COG1132	(ABC) transporter
SWP_RS07430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SWP_RS07435	COG0513	Belongs to the DEAD box helicase family
SWP_RS07445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SWP_RS07450	COG0784	Response regulator, receiver
SWP_RS07450	COG0835	chemotaxis
SWP_RS07455	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
SWP_RS07460	COG0673	inositol 2-dehydrogenase activity
SWP_RS07470	COG0564	pseudouridine synthase activity
SWP_RS07480	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SWP_RS07485	COG0343	queuine tRNA-ribosyltransferase activity
SWP_RS07490	COG1862	Preprotein translocase
SWP_RS07495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SWP_RS07500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SWP_RS07515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SWP_RS07515	COG1648	precorrin-2 dehydrogenase activity
SWP_RS07520	COG4681	YaeQ
SWP_RS07540	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SWP_RS07550	COG1959	2 iron, 2 sulfur cluster binding
SWP_RS07555	COG1104	cysteine desulfurase activity
SWP_RS07560	COG0822	iron-sulfur transferase activity
SWP_RS07565	COG0316	Belongs to the HesB IscA family
SWP_RS07570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SWP_RS07575	COG0443	Heat shock 70 kDa protein
SWP_RS07585	COG2975	iron-sulfur cluster assembly
SWP_RS07590	COG0105	UTP biosynthetic process
SWP_RS07605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SWP_RS07615	COG3220	belongs to the UPF0276 family
SWP_RS07625	COG2832	Protein of unknown function (DUF454)
SWP_RS07630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SWP_RS07635	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SWP_RS07640	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SWP_RS07645	COG0641	radical SAM
SWP_RS07650	COG2197	response regulator
SWP_RS07660	COG3119	arylsulfatase activity
SWP_RS07665	COG0714	Associated with various cellular activities
SWP_RS07685	COG2304	oxidoreductase activity
SWP_RS07700	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SWP_RS07705	COG0326	Molecular chaperone. Has ATPase activity
SWP_RS07710	COG3118	belongs to the thioredoxin family
SWP_RS07715	COG0563	adenylate kinase activity
SWP_RS07720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SWP_RS07725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SWP_RS07730	COG0110	maltose O-acetyltransferase activity
SWP_RS07735	COG1301	dicarboxylic acid transport
SWP_RS07745	COG3724	N-succinylarginine dihydrolase activity
SWP_RS07765	COG1760	l-serine dehydratase
SWP_RS07770	COG1472	Belongs to the glycosyl hydrolase 3 family
SWP_RS07780	COG3150	esterase
SWP_RS07790	COG1254	Belongs to the acylphosphatase family
SWP_RS07800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SWP_RS07810	COG4591	ABC-type transport system involved in lipoprotein release permease component
SWP_RS07820	COG4591	ABC-type transport system involved in lipoprotein release permease component
SWP_RS07860	COG3102	Protein conserved in bacteria
SWP_RS07870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SWP_RS07885	COG3097	Belongs to the UPF0267 family
SWP_RS08000	COG0367	asparagine synthase
SWP_RS08020	COG1620	l-lactate permease
SWP_RS08045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SWP_RS08050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SWP_RS08055	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SWP_RS08060	COG2056	Na+-H+ antiporter family
SWP_RS08065	COG0450	alkyl hydroperoxide reductase
SWP_RS08080	COG2885	chlorophyll binding
SWP_RS08085	COG1505	serine-type exopeptidase activity
SWP_RS08090	COG0824	Thioesterase
SWP_RS08095	COG0811	peptide transport
SWP_RS08110	COG0823	Involved in the tonB-independent uptake of proteins
SWP_RS08115	COG2885	chlorophyll binding
SWP_RS08120	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
SWP_RS08145	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SWP_RS08150	COG1061	Type III restriction enzyme res subunit
SWP_RS08155	COG0583	DNA-binding transcription factor activity
SWP_RS08160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SWP_RS08165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SWP_RS08170	COG5002	protein histidine kinase activity
SWP_RS08180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SWP_RS08190	COG1607	acyl-coa hydrolase
SWP_RS08200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SWP_RS08205	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SWP_RS08210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SWP_RS08210	COG0574	Belongs to the PEP-utilizing enzyme family
SWP_RS08215	COG0277	FAD linked oxidase domain protein
SWP_RS08215	COG0247	lactate metabolic process
SWP_RS08255	COG2850	peptidyl-arginine hydroxylation
SWP_RS08260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SWP_RS08265	COG2915	High frequency lysogenization protein hflD homolog
SWP_RS08270	COG0482	sulfurtransferase activity
SWP_RS08280	COG1187	pseudouridine synthase activity
SWP_RS08290	COG1278	Cold shock
SWP_RS08295	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SWP_RS08300	COG0542	response to heat
SWP_RS08305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SWP_RS08310	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
SWP_RS08315	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
SWP_RS08320	COG3134	Outer membrane lipoprotein
SWP_RS08335	COG1506	peptidase
SWP_RS08335	COG0823	Involved in the tonB-independent uptake of proteins
SWP_RS08335	COG4946	Tricorn protease homolog
SWP_RS08350	COG1054	Belongs to the UPF0176 family
SWP_RS08355	COG0330	HflC and HflK could
SWP_RS08365	COG0443	Heat shock 70 kDa protein
SWP_RS08380	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
SWP_RS08385	COG1162	GTPase activity
SWP_RS08405	COG1716	ATPase activity
SWP_RS08405	COG5001	Diguanylate cyclase
SWP_RS08420	COG2350	Protein conserved in bacteria
SWP_RS08425	COG2917	probably involved in intracellular septation
SWP_RS08495	COG0133	tryptophan synthase activity
SWP_RS08500	COG0135	phosphoribosylanthranilate isomerase activity
SWP_RS08500	COG0134	indole-3-glycerol-phosphate synthase activity
SWP_RS08510	COG0512	Glutamine amidotransferase of anthranilate synthase
SWP_RS08515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SWP_RS08525	COG0009	L-threonylcarbamoyladenylate synthase
SWP_RS08535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SWP_RS08540	COG1187	pseudouridine synthase activity
SWP_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS08550	COG2267	carboxylic ester hydrolase activity
SWP_RS08555	COG0616	signal peptide processing
SWP_RS08585	COG4181	ATPase activity
SWP_RS08590	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
SWP_RS08595	COG1090	epimerase
SWP_RS08600	COG0628	permease
SWP_RS08605	COG0116	Belongs to the methyltransferase superfamily
SWP_RS08605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SWP_RS08615	COG0280	phosphate acetyltransferase
SWP_RS08615	COG0857	belongs to the CobB CobQ family
SWP_RS08620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SWP_RS08625	COG3092	negative regulation of chromosome organization
SWP_RS08630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SWP_RS08635	COG1882	Formate acetyltransferase
SWP_RS08645	COG2116	formate transmembrane transporter activity
SWP_RS08650	COG0583	DNA-binding transcription factor activity
SWP_RS08655	COG1288	antiporter activity
SWP_RS08660	COG4206	TonB-dependent receptor
SWP_RS08680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SWP_RS08705	COG1196	nuclear chromosome segregation
SWP_RS08710	COG3115	cell septum assembly
SWP_RS08715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SWP_RS08745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SWP_RS08750	COG0517	IMP dehydrogenase activity
SWP_RS08750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SWP_RS08760	COG0784	Response regulator, receiver
SWP_RS08760	COG2205	protein histidine kinase activity
SWP_RS08775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SWP_RS08785	COG1012	belongs to the aldehyde dehydrogenase family
SWP_RS08790	COG3938	Belongs to the proline racemase family
SWP_RS08800	COG3938	Belongs to the proline racemase family
SWP_RS08805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SWP_RS08810	COG0006	proline dipeptidase activity
SWP_RS08815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SWP_RS08850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SWP_RS08855	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SWP_RS08855	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SWP_RS08860	COG1072	(Pantothenic acid kinase))
SWP_RS08880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SWP_RS08895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SWP_RS08900	COG0081	regulation of translation
SWP_RS08905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SWP_RS08910	COG0222	ribosome binding
SWP_RS08915	COG0085	RNA polymerase activity
SWP_RS08920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SWP_RS08925	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SWP_RS08930	COG0049	tRNA binding
SWP_RS08935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SWP_RS08940	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SWP_RS08950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SWP_RS08955	COG0088	Forms part of the polypeptide exit tunnel
SWP_RS08960	COG0089	rRNA binding
SWP_RS08965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SWP_RS08970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SWP_RS08975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SWP_RS08980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SWP_RS08985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SWP_RS08990	COG0255	Belongs to the universal ribosomal protein uL29 family
SWP_RS08995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SWP_RS09000	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SWP_RS09005	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SWP_RS09010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SWP_RS09015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SWP_RS09020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SWP_RS09025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SWP_RS09030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SWP_RS09035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SWP_RS09040	COG1841	ribosomal large subunit assembly
SWP_RS09045	COG0200	Binds to the 23S rRNA
SWP_RS09050	COG0201	protein transport
SWP_RS09055	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SWP_RS09060	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SWP_RS09065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SWP_RS09070	COG0202	RNA polymerase activity
SWP_RS09075	COG0203	ribosomal protein L17
SWP_RS09080	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
SWP_RS09085	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SWP_RS09090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SWP_RS09095	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SWP_RS09110	COG3088	subunit of a heme lyase
SWP_RS09110	COG4235	cytochrome complex assembly
SWP_RS09125	COG4235	cytochrome complex assembly
SWP_RS09125	COG3088	subunit of a heme lyase
SWP_RS09130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SWP_RS09150	COG1546	Belongs to the CinA family
SWP_RS09150	COG1058	Belongs to the CinA family
SWP_RS09160	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SWP_RS09170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SWP_RS09175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SWP_RS09180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SWP_RS09185	COG0137	argininosuccinate synthase activity
SWP_RS09190	COG0165	Argininosuccinate lyase
SWP_RS09195	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SWP_RS09225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SWP_RS09230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SWP_RS09240	COG0338	D12 class N6 adenine-specific DNA methyltransferase
SWP_RS09255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SWP_RS09265	COG0180	Tryptophanyl-tRNA synthetase
SWP_RS09270	COG0583	DNA-binding transcription factor activity
SWP_RS09275	COG0697	spore germination
SWP_RS09280	COG2823	Periplasmic or secreted lipoprotein
SWP_RS09285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SWP_RS09290	COG0792	nuclease activity
SWP_RS09300	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SWP_RS09310	COG4771	TonB-dependent receptor
SWP_RS09320	COG1858	cytochrome C peroxidase
SWP_RS09330	COG1752	Esterase of the alpha-beta hydrolase superfamily
SWP_RS09335	COG0583	DNA-binding transcription factor activity
SWP_RS09340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SWP_RS09345	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SWP_RS09355	COG3708	Transcriptional regulator
SWP_RS09355	COG2207	Transcriptional regulator
SWP_RS09370	COG1120	ATPase activity
SWP_RS09375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SWP_RS09405	COG4948	Mandelate Racemase Muconate Lactonizing
SWP_RS09415	COG0583	DNA-binding transcription factor activity
SWP_RS09420	COG1757	Na H antiporter
SWP_RS09425	COG4206	TonB-dependent receptor
SWP_RS09445	COG1252	NADH dehydrogenase
SWP_RS09465	COG1404	Belongs to the peptidase S8 family
SWP_RS09475	COG0823	Involved in the tonB-independent uptake of proteins
SWP_RS09495	COG1032	radical SAM domain protein
SWP_RS09550	COG3381	protein complex oligomerization
SWP_RS09555	COG0437	4 iron, 4 sulfur cluster binding
SWP_RS09560	COG0243	molybdopterin cofactor binding
SWP_RS09670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SWP_RS09675	COG1366	Belongs to the anti-sigma-factor antagonist family
SWP_RS09680	COG0745	RESPONSE REGULATOR receiver
SWP_RS09705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SWP_RS09710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SWP_RS09720	COG3074	FtsZ-dependent cytokinesis
SWP_RS09725	COG1757	Na H antiporter
SWP_RS09740	COG0243	molybdopterin cofactor binding
SWP_RS09760	COG3550	peptidyl-serine autophosphorylation
SWP_RS09805	COG1561	YicC-like family, N-terminal region
SWP_RS09810	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SWP_RS09815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SWP_RS09820	COG0302	gtp cyclohydrolase
SWP_RS09830	COG1309	transcriptional regulator
SWP_RS09835	COG0756	dUTP diphosphatase activity
SWP_RS09845	COG2003	Belongs to the UPF0758 family
SWP_RS09850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SWP_RS09855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SWP_RS09860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SWP_RS09860	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SWP_RS09870	COG2962	Rard protein
SWP_RS09875	COG2050	protein possibly involved in aromatic compounds catabolism
SWP_RS09890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SWP_RS09895	COG0473	3-isopropylmalate dehydrogenase activity
SWP_RS09900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SWP_RS09905	COG0066	3-isopropylmalate dehydratase activity
SWP_RS09910	COG2067	long-chain fatty acid transport protein
SWP_RS09920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SWP_RS09930	COG2001	Belongs to the MraZ family
SWP_RS09935	COG0275	rRNA processing
SWP_RS09940	COG3116	cell division
SWP_RS09945	COG0768	penicillin binding
SWP_RS09950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SWP_RS09955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SWP_RS09960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SWP_RS09965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SWP_RS09970	COG0772	Belongs to the SEDS family
SWP_RS09975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SWP_RS09980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SWP_RS09985	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SWP_RS09990	COG0849	cell division
SWP_RS09995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SWP_RS10000	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SWP_RS10010	COG0739	heme binding
SWP_RS10015	COG0653	protein targeting
SWP_RS10035	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
SWP_RS10045	COG0598	Magnesium transport protein CorA
SWP_RS10075	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SWP_RS10080	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SWP_RS10085	COG3639	organic phosphonate transmembrane transporter activity
SWP_RS10105	COG2204	response regulator
SWP_RS10110	COG1280	lysine exporter protein (LysE YggA)
SWP_RS10120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SWP_RS10135	COG3706	GGDEF domain
SWP_RS10155	COG3082	Protein of unknown function (DUF1414)
SWP_RS10160	COG3081	Nucleoid-associated protein
SWP_RS10180	COG0658	competence protein
SWP_RS10180	COG2333	competence protein COMEC
SWP_RS10185	COG1132	(ABC) transporter
SWP_RS10190	COG1663	tetraacyldisaccharide 4'-kinase activity
SWP_RS10195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SWP_RS10200	COG0339	signal peptide processing
SWP_RS10210	COG1214	PFAM Peptidase M22, glycoprotease
SWP_RS10230	COG2267	carboxylic ester hydrolase activity
SWP_RS10235	COG0318	PFAM AMP-dependent synthetase and ligase
SWP_RS10240	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SWP_RS10245	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SWP_RS10250	COG2894	cell division
SWP_RS10255	COG0850	regulation of cytokinetic process
SWP_RS10260	COG3100	YcgL domain-containing protein
SWP_RS10265	COG2951	lytic endotransglycosylase activity
SWP_RS10270	COG2983	Belongs to the UPF0260 family
SWP_RS10275	COG1388	LysM domain
SWP_RS10275	COG0741	lytic transglycosylase activity
SWP_RS10280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SWP_RS10285	COG2226	methyltransferase
SWP_RS10290	COG0583	DNA-binding transcription factor activity
SWP_RS10295	COG0328	RNA-DNA hybrid ribonuclease activity
SWP_RS10300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SWP_RS10335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SWP_RS10350	COG0121	glutamine amidotransferase
SWP_RS10355	COG3437	response regulator, receiver
SWP_RS10360	COG0784	Response regulator, receiver
SWP_RS10360	COG2205	protein histidine kinase activity
SWP_RS10360	COG5002	protein histidine kinase activity
SWP_RS10380	COG0477	Major facilitator Superfamily
SWP_RS10385	COG0242	peptide deformylase activity
SWP_RS10400	COG0587	DNA-directed DNA polymerase activity
SWP_RS10415	COG1272	protein, Hemolysin III
SWP_RS10425	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SWP_RS10435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SWP_RS10445	COG2022	thiamine diphosphate biosynthetic process
SWP_RS10450	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SWP_RS10460	COG0745	RESPONSE REGULATOR receiver
SWP_RS10495	COG0189	ligase activity
SWP_RS10495	COG4067	protein conserved in archaea
SWP_RS10500	COG0500	methyltransferase
SWP_RS10505	COG2226	methyltransferase
SWP_RS10515	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SWP_RS10520	COG0217	transcriptional regulatory protein
SWP_RS10525	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SWP_RS10530	COG0632	four-way junction helicase activity
SWP_RS10535	COG2255	four-way junction helicase activity
SWP_RS10570	COG0346	lactoylglutathione lyase activity
SWP_RS10575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SWP_RS10580	COG4660	Part of a membrane complex involved in electron transport
SWP_RS10585	COG4659	FMN binding
SWP_RS10590	COG4658	electron transport chain
SWP_RS10600	COG2878	Part of a membrane complex involved in electron transport
SWP_RS10605	COG4657	Part of a membrane complex involved in electron transport
SWP_RS10610	COG2200	EAL domain
SWP_RS10640	COG0556	nucleotide-excision repair
SWP_RS10650	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SWP_RS10655	COG0602	queuosine metabolic process
SWP_RS10660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SWP_RS10695	COG3012	SEC-C Motif Domain Protein
SWP_RS10705	COG2840	Smr protein MutS2
SWP_RS10720	COG1960	acyl-CoA dehydrogenase activity
SWP_RS10725	COG0469	pyruvate kinase activity
SWP_RS10730	COG1737	Transcriptional regulator
SWP_RS10735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SWP_RS10740	COG0363	glucosamine-6-phosphate deaminase activity
SWP_RS10745	COG0129	dihydroxy-acid dehydratase activity
SWP_RS10750	COG0800	Aldolase
SWP_RS10755	COG4574	serine-type endopeptidase inhibitor activity
SWP_RS10760	COG1230	cation diffusion facilitator family transporter
SWP_RS10770	COG2194	sulfuric ester hydrolase activity
SWP_RS10780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SWP_RS10780	COG1042	CoA-binding domain protein
SWP_RS10780	COG0045	succinate-CoA ligase (ADP-forming) activity
SWP_RS10785	COG0714	Associated with various cellular activities
SWP_RS10805	COG2304	oxidoreductase activity
SWP_RS10835	COG0641	radical SAM
SWP_RS10855	COG4585	Histidine kinase
SWP_RS10860	COG3119	arylsulfatase activity
SWP_RS10875	COG0583	DNA-binding transcription factor activity
SWP_RS10880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS10890	COG1538	Outer membrane efflux protein
SWP_RS10895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS10910	COG1802	Transcriptional regulator
SWP_RS10915	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SWP_RS10920	COG0372	Belongs to the citrate synthase family
SWP_RS10925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SWP_RS10955	COG1566	PFAM secretion protein HlyD family protein
SWP_RS10975	COG1944	ATP diphosphatase activity
SWP_RS10985	COG0488	(ABC) transporter
SWP_RS10990	COG4628	conserved protein (DUF2132)
SWP_RS10995	COG3119	arylsulfatase activity
SWP_RS11000	COG2169	Transcriptional regulator
SWP_RS11010	COG4948	Mandelate Racemase Muconate Lactonizing
SWP_RS11015	COG1757	Na H antiporter
SWP_RS11020	COG0626	cystathionine gamma-synthase activity
SWP_RS11065	COG0534	Mate efflux family protein
SWP_RS11070	COG0307	riboflavin synthase, alpha
SWP_RS11080	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS11090	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SWP_RS11095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SWP_RS11100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SWP_RS11105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SWP_RS11110	COG0492	ferredoxin-NADP+ reductase activity
SWP_RS11115	COG2866	Carboxypeptidase
SWP_RS11125	COG3139	Protein of unknown function (DUF1315)
SWP_RS11130	COG0252	asparaginase activity
SWP_RS11135	COG0616	signal peptide processing
SWP_RS11140	COG0446	pyridine nucleotide-disulphide oxidoreductase
SWP_RS11140	COG1902	pentaerythritol trinitrate reductase activity
SWP_RS11155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SWP_RS11165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SWP_RS11175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SWP_RS11190	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SWP_RS11195	COG1448	Aminotransferase
SWP_RS11200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SWP_RS11205	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SWP_RS11210	COG0539	negative regulation of cytoplasmic translation
SWP_RS11215	COG0776	regulation of translation
SWP_RS11225	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
SWP_RS11230	COG0284	orotidine-5'-phosphate decarboxylase activity
SWP_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS11240	COG3122	Protein conserved in bacteria
SWP_RS11260	COG1960	acyl-CoA dehydrogenase activity
SWP_RS11265	COG2027	D-alanyl-D-alanine carboxypeptidase
SWP_RS11275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SWP_RS11280	COG3148	PFAM DTW domain containing protein
SWP_RS11290	COG2963	transposase activity
SWP_RS11295	COG2801	Transposase and inactivated derivatives
SWP_RS11300	COG4566	intracellular signal transduction
SWP_RS11310	COG1477	protein flavinylation
SWP_RS11325	COG0564	pseudouridine synthase activity
SWP_RS11330	COG0308	aminopeptidase N
SWP_RS11335	COG0737	Belongs to the 5'-nucleotidase family
SWP_RS11380	COG0456	acetyltransferase
SWP_RS11385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SWP_RS11400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SWP_RS11430	COG2920	part of a sulfur-relay system
SWP_RS11435	COG2168	tRNA wobble position uridine thiolation
SWP_RS11440	COG2923	Belongs to the DsrF TusC family
SWP_RS11445	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
SWP_RS11450	COG0670	Belongs to the BI1 family
SWP_RS11455	COG0583	DNA-binding transcription factor activity
SWP_RS11460	COG2814	Major facilitator Superfamily
SWP_RS11480	COG0653	protein targeting
SWP_RS11485	COG1227	inorganic diphosphatase activity
SWP_RS11490	COG1067	ATP-dependent peptidase activity
SWP_RS11495	COG0826	peptidase U32
SWP_RS11520	COG2910	NAD(P)H-binding
SWP_RS11525	COG0583	DNA-binding transcription factor activity
SWP_RS11585	COG3278	Belongs to the heme-copper respiratory oxidase family
SWP_RS11600	COG2010	Cytochrome c
SWP_RS11610	COG2217	Heavy metal translocating P-type atpase
SWP_RS11625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SWP_RS11630	COG0589	response to stress
SWP_RS11635	COG0037	tRNA processing
SWP_RS11645	COG2992	FlgJ-related protein
SWP_RS11655	COG1448	Aminotransferase
SWP_RS11660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SWP_RS11665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SWP_RS11670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SWP_RS11675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SWP_RS11680	COG0531	amino acid
SWP_RS11680	COG1674	ftsk spoiiie
SWP_RS11690	COG0686	Belongs to the AlaDH PNT family
SWP_RS11695	COG0745	RESPONSE REGULATOR receiver
SWP_RS11705	COG0514	ATP-dependent DNA helicase (RecQ)
SWP_RS11710	COG3021	interspecies interaction between organisms
SWP_RS11745	COG0022	dehydrogenase e1 component
SWP_RS11755	COG2988	succinylglutamate desuccinylase activity
SWP_RS11760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SWP_RS11765	COG0033	Phosphoglucomutase
SWP_RS11770	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
SWP_RS11775	COG0596	Alpha beta hydrolase
SWP_RS11800	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SWP_RS11805	COG0436	Aminotransferase
SWP_RS11810	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
SWP_RS11815	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SWP_RS11820	COG2095	MarC family integral membrane protein
SWP_RS11825	COG1012	belongs to the aldehyde dehydrogenase family
SWP_RS11825	COG1454	alcohol dehydrogenase
SWP_RS11830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SWP_RS11850	COG2329	Antibiotic biosynthesis monooxygenase
SWP_RS11855	COG1506	peptidase
SWP_RS11855	COG0823	Involved in the tonB-independent uptake of proteins
SWP_RS11870	COG0494	nUDIX hydrolase
SWP_RS11880	COG0017	Asparaginyl-tRNA synthetase
SWP_RS11885	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SWP_RS11890	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SWP_RS11895	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
SWP_RS11900	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SWP_RS11910	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SWP_RS11915	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SWP_RS11920	COG0298	carbon dioxide binding
SWP_RS11925	COG0409	Hydrogenase expression formation protein
SWP_RS11930	COG0309	Hydrogenase expression formation protein (HypE)
SWP_RS11935	COG0375	protein maturation
SWP_RS11970	COG4964	Belongs to the GSP D family
SWP_RS12000	COG2989	Protein conserved in bacteria
SWP_RS12020	COG0432	Pfam Uncharacterised protein family UPF0047
SWP_RS12025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SWP_RS12025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SWP_RS12035	COG0366	Alpha amylase catalytic
SWP_RS12045	COG0366	Alpha amylase catalytic
SWP_RS12055	COG1082	Xylose isomerase domain protein TIM barrel
SWP_RS12060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SWP_RS12095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SWP_RS12105	COG2850	peptidyl-arginine hydroxylation
SWP_RS12115	COG1230	cation diffusion facilitator family transporter
SWP_RS12130	COG0840	transmembrane signaling receptor activity
SWP_RS12140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SWP_RS12145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SWP_RS12155	COG1393	Belongs to the ArsC family
SWP_RS12160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SWP_RS12165	COG1876	peptidase activity
SWP_RS12170	COG0596	Alpha beta hydrolase
SWP_RS12175	COG0288	reversible hydration of carbon dioxide
SWP_RS12180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SWP_RS12185	COG1454	alcohol dehydrogenase
SWP_RS12190	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SWP_RS12210	COG3209	COG3209 Rhs family protein
SWP_RS12225	COG4974	Belongs to the 'phage' integrase family
SWP_RS12235	COG1484	DNA-dependent DNA replication
SWP_RS12275	COG2963	transposase activity
SWP_RS12280	COG2801	Transposase and inactivated derivatives
SWP_RS12310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SWP_RS12315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS12320	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
SWP_RS12325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SWP_RS12330	COG2716	regulation of RNA biosynthetic process
SWP_RS12335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SWP_RS12340	COG1279	arginine transmembrane transporter activity
SWP_RS12360	COG4783	chaperone-mediated protein folding
SWP_RS12365	COG1393	Belongs to the ArsC family
SWP_RS12395	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SWP_RS12430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SWP_RS12435	COG1322	Protein conserved in bacteria
SWP_RS12440	COG0741	lytic transglycosylase activity
SWP_RS12450	COG0714	Associated with various cellular activities
SWP_RS12465	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SWP_RS12470	COG1074	ATP-dependent DNA helicase activity
SWP_RS12475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SWP_RS12480	COG1181	Belongs to the D-alanine--D-alanine ligase family
SWP_RS12485	COG3005	denitrification pathway
SWP_RS12495	COG0243	molybdopterin cofactor binding
SWP_RS12505	COG1643	Atp-dependent helicase
SWP_RS12525	COG1446	asparaginase
SWP_RS12530	COG0729	surface antigen
SWP_RS12540	COG2186	Transcriptional regulator
SWP_RS12545	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SWP_RS12550	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SWP_RS12555	COG2766	serine protein kinase
SWP_RS12560	COG2718	Belongs to the UPF0229 family
SWP_RS12565	COG2719	SpoVR family
SWP_RS12570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SWP_RS12575	COG3108	Peptidase M15
SWP_RS12580	COG2989	Protein conserved in bacteria
SWP_RS12585	COG2165	general secretion pathway protein
SWP_RS12610	COG0322	excinuclease ABC activity
SWP_RS12625	COG1067	ATP-dependent peptidase activity
SWP_RS12630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SWP_RS12635	COG3130	regulation of translation
SWP_RS12645	COG0488	(ABC) transporter
SWP_RS12655	COG0116	Belongs to the methyltransferase superfamily
SWP_RS12655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SWP_RS12660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SWP_RS12670	COG0167	dihydroorotate dehydrogenase activity
SWP_RS12700	COG0308	aminopeptidase N
SWP_RS12705	COG0793	Belongs to the peptidase S41A family
SWP_RS12710	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
SWP_RS12715	COG1956	GAF domain-containing protein
SWP_RS12720	COG3141	response to X-ray
SWP_RS12725	COG2995	paraquat-inducible protein a
SWP_RS12730	COG2995	paraquat-inducible protein a
SWP_RS12735	COG3008	intermembrane lipid transfer
SWP_RS12740	COG2715	membrane protein required for spore maturation
SWP_RS12745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SWP_RS12745	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SWP_RS12750	COG0084	hydrolase, TatD family'
SWP_RS12770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SWP_RS12775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SWP_RS12780	COG0572	uridine kinase
SWP_RS12785	COG0489	protein tyrosine kinase activity
SWP_RS12790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SWP_RS12790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SWP_RS12795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SWP_RS12805	COG2814	Major facilitator Superfamily
SWP_RS12810	COG0028	Belongs to the TPP enzyme family
SWP_RS12830	COG0400	carboxylic ester hydrolase activity
SWP_RS12835	COG0435	Glutathione S-transferase
SWP_RS12855	COG2951	lytic endotransglycosylase activity
SWP_RS12870	COG0784	Response regulator, receiver
SWP_RS12870	COG0835	chemotaxis
SWP_RS12875	COG0668	transmembrane transport
SWP_RS12890	COG2267	carboxylic ester hydrolase activity
SWP_RS12910	COG1858	cytochrome C peroxidase
SWP_RS12925	COG0583	DNA-binding transcription factor activity
SWP_RS12940	COG1280	lysine exporter protein (LysE YggA)
SWP_RS12950	COG0405	Gamma-glutamyltransferase
SWP_RS12965	COG2871	sodium ion transport
SWP_RS12970	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SWP_RS12975	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SWP_RS12980	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SWP_RS12985	COG1805	sodium ion transport
SWP_RS12990	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SWP_RS13000	COG0577	efflux transmembrane transporter activity
SWP_RS13000	COG1136	(ABC) transporter
SWP_RS13020	COG0577	efflux transmembrane transporter activity
SWP_RS13020	COG1136	(ABC) transporter
SWP_RS13040	COG0778	Nitroreductase
SWP_RS13070	COG4773	Receptor
SWP_RS13090	COG0537	adenosine 5'-monophosphoramidase activity
SWP_RS13095	COG2197	response regulator
SWP_RS13105	COG2815	serine threonine protein kinase
SWP_RS13105	COG0515	serine threonine protein kinase
SWP_RS13110	COG2223	nitrite transmembrane transporter activity
SWP_RS13120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SWP_RS13120	COG2146	nitrite reductase [NAD(P)H] activity
SWP_RS13140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SWP_RS13140	COG1648	precorrin-2 dehydrogenase activity
SWP_RS13145	COG0243	molybdopterin cofactor binding
SWP_RS13150	COG1053	succinate dehydrogenase
SWP_RS13155	COG0501	Belongs to the peptidase M48B family
SWP_RS13160	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SWP_RS13165	COG2226	methyltransferase
SWP_RS13170	COG0156	8-amino-7-oxononanoate synthase activity
SWP_RS13175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SWP_RS13180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SWP_RS13195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SWP_RS13210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SWP_RS13215	COG0735	belongs to the Fur family
SWP_RS13225	COG0069	glutamate synthase activity
SWP_RS13245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SWP_RS13250	COG0045	succinate-CoA ligase (ADP-forming) activity
SWP_RS13255	COG0508	dehydrogenase complex catalyzes the overall conversion of
SWP_RS13260	COG0567	Dehydrogenase, E1 component
SWP_RS13265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SWP_RS13275	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
SWP_RS13290	COG0372	Belongs to the citrate synthase family
SWP_RS13300	COG0346	lactoylglutathione lyase activity
SWP_RS13305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SWP_RS13310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS13350	COG1011	Hydrolase
SWP_RS13365	COG1960	acyl-CoA dehydrogenase activity
SWP_RS13370	COG0676	glucose-6-phosphate 1-epimerase activity
SWP_RS13385	COG3784	Protein of unknown function (DUF1318)
SWP_RS13390	COG0628	permease
SWP_RS13410	COG3710	Transcriptional regulator
SWP_RS13425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS13430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SWP_RS13450	COG1199	ATP-dependent helicase activity
SWP_RS13455	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SWP_RS13460	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SWP_RS13465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SWP_RS13470	COG0131	Imidazoleglycerol-phosphate dehydratase
SWP_RS13470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SWP_RS13475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SWP_RS13480	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SWP_RS13485	COG0107	imidazoleglycerol-phosphate synthase activity
SWP_RS13490	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SWP_RS13490	COG0140	phosphoribosyl-ATP diphosphatase activity
SWP_RS13500	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SWP_RS13505	COG1560	Kdo2-lipid A biosynthetic process
SWP_RS13510	COG0776	regulation of translation
SWP_RS13515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SWP_RS13515	COG0072	phenylalanine-tRNA ligase activity
SWP_RS13520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SWP_RS13535	COG0189	ligase activity
SWP_RS13535	COG4067	protein conserved in archaea
SWP_RS13555	COG0259	pyridoxamine-phosphate oxidase activity
SWP_RS13560	COG0010	Belongs to the arginase family
SWP_RS13570	COG1166	arginine decarboxylase activity
SWP_RS13580	COG3132	Protein of unknown function, DUF480
SWP_RS13595	COG1278	Cold shock
SWP_RS13600	COG2226	methyltransferase
SWP_RS13610	COG2925	Exonuclease
SWP_RS13615	COG0295	cytidine deaminase activity
SWP_RS13620	COG2084	Dehydrogenase
SWP_RS13635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SWP_RS13640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SWP_RS13645	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS13650	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SWP_RS13655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SWP_RS13660	COG0416	fatty acid biosynthetic process
SWP_RS13665	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SWP_RS13670	COG1399	metal-binding, possibly nucleic acid-binding protein
SWP_RS13685	COG0546	phosphoglycolate phosphatase activity
SWP_RS13695	COG1530	ribonuclease E activity
SWP_RS13700	COG0659	secondary active sulfate transmembrane transporter activity
SWP_RS13705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SWP_RS13715	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SWP_RS13760	COG0745	RESPONSE REGULATOR receiver
SWP_RS13770	COG0811	peptide transport
SWP_RS13785	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
SWP_RS13805	COG1793	dna ligase
SWP_RS13810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SWP_RS13825	COG3706	GGDEF domain
SWP_RS13840	COG2885	chlorophyll binding
SWP_RS13840	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
SWP_RS13845	COG0745	RESPONSE REGULATOR receiver
SWP_RS13850	COG2205	protein histidine kinase activity
SWP_RS13855	COG0626	cystathionine gamma-synthase activity
SWP_RS13860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SWP_RS13915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SWP_RS13925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SWP_RS13930	COG1286	toxin biosynthetic process
SWP_RS13935	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
SWP_RS13940	COG0285	dihydrofolate synthase activity
SWP_RS13945	COG0101	tRNA pseudouridine synthase activity
SWP_RS13960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SWP_RS13970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SWP_RS13975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SWP_RS14005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SWP_RS14010	COG2890	protein-(glutamine-N5) methyltransferase activity
SWP_RS14015	COG2840	Smr protein MutS2
SWP_RS14020	COG2062	phosphohistidine phosphatase, SixA
SWP_RS14025	COG1025	Belongs to the peptidase M16 family
SWP_RS14030	COG5001	Diguanylate cyclase
SWP_RS14030	COG3300	MHYT domain
SWP_RS14045	COG1250	3-hydroxyacyl-CoA dehydrogenase
SWP_RS14045	COG1024	Enoyl-CoA hydratase
SWP_RS14050	COG0183	Belongs to the thiolase family
SWP_RS14055	COG0714	Associated with various cellular activities
SWP_RS14085	COG1595	DNA-templated transcription, initiation
SWP_RS14095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SWP_RS14135	COG4628	conserved protein (DUF2132)
SWP_RS14145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SWP_RS14155	COG0602	queuosine metabolic process
SWP_RS14170	COG1846	Transcriptional regulator
SWP_RS14175	COG2130	NADP-dependent
SWP_RS14180	COG1752	Esterase of the alpha-beta hydrolase superfamily
SWP_RS14185	COG0513	Belongs to the DEAD box helicase family
SWP_RS14200	COG1451	nucleotide metabolic process
SWP_RS14210	COG0739	heme binding
SWP_RS14215	COG0419	ATPase involved in DNA repair
SWP_RS14220	COG0420	3'-5' exonuclease activity
SWP_RS14230	COG0745	RESPONSE REGULATOR receiver
SWP_RS14245	COG3977	Valine--pyruvate aminotransferase
SWP_RS14250	COG4206	TonB-dependent receptor
SWP_RS14295	COG0730	response to heat
SWP_RS14300	COG0583	DNA-binding transcription factor activity
SWP_RS14325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SWP_RS14350	COG0848	biopolymer transport protein
SWP_RS14355	COG0811	peptide transport
SWP_RS14360	COG0811	peptide transport
SWP_RS14370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SWP_RS14375	COG0417	DNA replication proofreading
SWP_RS14380	COG1199	ATP-dependent helicase activity
SWP_RS14385	COG0730	response to heat
SWP_RS14400	COG0123	including yeast histone deacetylase and acetoin utilization protein
SWP_RS14515	COG0471	metal ion transport
SWP_RS14525	COG3768	UPF0283 membrane protein
SWP_RS14530	COG3106	COG3106 Predicted ATPase
SWP_RS14535	COG1983	PspC domain protein
SWP_RS14545	COG1842	Phage shock protein A
SWP_RS14550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SWP_RS14555	COG0747	negative chemotaxis
SWP_RS14560	COG4168	peptide transport system, permease
SWP_RS14565	COG4171	peptide transport system, permease
SWP_RS14575	COG4172	Belongs to the ABC transporter superfamily
SWP_RS14580	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SWP_RS14585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SWP_RS14595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SWP_RS14600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SWP_RS14605	COG0740	serine-type endopeptidase activity
SWP_RS14610	COG0544	peptidyl-prolyl cis-trans isomerase activity
SWP_RS14630	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SWP_RS14635	COG0215	cysteine-tRNA ligase activity
SWP_RS14640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SWP_RS14645	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SWP_RS14660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SWP_RS14730	COG1573	uracil-dna glycosylase
SWP_RS14755	COG3835	regulator
SWP_RS14760	COG2165	general secretion pathway protein
SWP_RS14770	COG1929	Belongs to the glycerate kinase type-1 family
SWP_RS14775	COG0076	glutamate decarboxylase activity
SWP_RS14780	COG4106	trans-aconitate 2-methyltransferase activity
SWP_RS14795	COG3344	reverse transcriptase
SWP_RS14800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SWP_RS14805	COG0564	pseudouridine synthase activity
SWP_RS14820	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS14845	COG0826	peptidase U32
SWP_RS14870	COG0517	IMP dehydrogenase activity
SWP_RS14880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SWP_RS14890	COG1741	Belongs to the pirin family
SWP_RS14895	COG0583	DNA-binding transcription factor activity
SWP_RS14900	COG1335	isochorismatase
SWP_RS14915	COG3852	Histidine kinase
SWP_RS14920	COG2204	response regulator
SWP_RS14925	COG0577	efflux transmembrane transporter activity
SWP_RS14925	COG1136	(ABC) transporter
SWP_RS14930	COG0577	efflux transmembrane transporter activity
SWP_RS14930	COG1136	(ABC) transporter
SWP_RS14945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SWP_RS14950	COG0318	PFAM AMP-dependent synthetase and ligase
SWP_RS14955	COG0596	Alpha beta hydrolase
SWP_RS14960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SWP_RS14985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SWP_RS14990	COG0704	Plays a role in the regulation of phosphate uptake
SWP_RS15000	COG0573	inorganic phosphate transmembrane transporter activity
SWP_RS15030	COG3291	Pkd domain containing protein
SWP_RS15055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SWP_RS15135	COG0488	(ABC) transporter
SWP_RS15140	COG2217	Heavy metal translocating P-type atpase
SWP_RS15140	COG2608	mercury ion transmembrane transporter activity
SWP_RS15145	COG0789	Transcriptional regulator
SWP_RS15160	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS15170	COG1024	Enoyl-CoA hydratase
SWP_RS15175	COG1024	Enoyl-CoA hydratase
SWP_RS15180	COG1960	acyl-CoA dehydrogenase activity
SWP_RS15200	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SWP_RS15205	COG3126	Type III secretion system lipoprotein chaperone (YscW)
SWP_RS15215	COG3047	cAMP biosynthetic process
SWP_RS15230	COG1946	Acyl-CoA thioesterase
SWP_RS15235	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS15240	COG1575	Belongs to the MenA family. Type 1 subfamily
SWP_RS15245	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
SWP_RS15260	COG2249	NAD(P)H dehydrogenase (quinone) activity
SWP_RS15320	COG1960	acyl-CoA dehydrogenase activity
SWP_RS15340	COG0456	acetyltransferase
SWP_RS15355	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SWP_RS15370	COG3344	reverse transcriptase
SWP_RS15385	COG1960	acyl-CoA dehydrogenase activity
SWP_RS15390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SWP_RS15395	COG1024	Enoyl-CoA hydratase
SWP_RS15400	COG4770	biotin carboxylase activity
SWP_RS15410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SWP_RS15415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SWP_RS15425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SWP_RS15445	COG0437	4 iron, 4 sulfur cluster binding
SWP_RS15450	COG0243	molybdopterin cofactor binding
SWP_RS15465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SWP_RS15480	COG1435	thymidine kinase activity
SWP_RS15485	COG0339	signal peptide processing
SWP_RS15490	COG1757	Na H antiporter
SWP_RS15515	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SWP_RS15525	COG1720	tRNA m6t6A37 methyltransferase activity
SWP_RS15530	COG0110	maltose O-acetyltransferase activity
SWP_RS15545	COG3152	Membrane
SWP_RS15550	COG0442	prolyl-tRNA aminoacylation
SWP_RS15615	COG0604	alcohol dehydrogenase
SWP_RS15630	COG2259	Doxx family
SWP_RS15645	COG2199	diguanylate cyclase activity
SWP_RS15650	COG0037	tRNA processing
SWP_RS15655	COG0587	DNA-directed DNA polymerase activity
SWP_RS15660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SWP_RS15665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SWP_RS15670	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SWP_RS15675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SWP_RS15680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SWP_RS15695	COG0750	zinc metalloprotease
SWP_RS15700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SWP_RS15705	COG0575	Belongs to the CDS family
SWP_RS15710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SWP_RS15715	COG0233	cytoplasmic translational termination
SWP_RS15720	COG0528	UMP kinase activity
SWP_RS15725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SWP_RS15730	COG0052	Belongs to the universal ribosomal protein uS2 family
SWP_RS15735	COG0024	Methionine aminopeptidase
SWP_RS15740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SWP_RS15745	COG2171	N-acyltransferase activity
SWP_RS15755	COG0788	formyltetrahydrofolate deformylase activity
SWP_RS15760	COG0716	FMN binding
SWP_RS15765	COG0564	pseudouridine synthase activity
SWP_RS15770	COG3098	single-species biofilm formation
SWP_RS15825	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
SWP_RS15840	COG0583	DNA-binding transcription factor activity
SWP_RS15845	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SWP_RS15880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SWP_RS15880	COG2070	2-Nitropropane dioxygenase
SWP_RS15885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SWP_RS15895	COG3706	GGDEF domain
SWP_RS15925	COG0513	Belongs to the DEAD box helicase family
SWP_RS15935	COG1473	amidohydrolase
SWP_RS15965	COG2205	protein histidine kinase activity
SWP_RS15970	COG3064	Membrane
SWP_RS15995	COG5001	Diguanylate cyclase
SWP_RS15995	COG3300	MHYT domain
SWP_RS16010	COG0390	transport system, permease component
SWP_RS16015	COG2195	Cleaves the N-terminal amino acid of tripeptides
SWP_RS16025	COG2384	SAM-dependent methyltransferase
SWP_RS16040	COG1595	DNA-templated transcription, initiation
SWP_RS16045	COG0786	glutamate:sodium symporter activity
SWP_RS16060	COG0023	Translation Initiation Factor
SWP_RS16065	COG1678	Uncharacterized ACR, COG1678
SWP_RS16070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SWP_RS16080	COG1506	peptidase
SWP_RS16080	COG0823	Involved in the tonB-independent uptake of proteins
SWP_RS16080	COG4946	Tricorn protease homolog
SWP_RS16085	COG0473	3-isopropylmalate dehydrogenase activity
SWP_RS16095	COG2363	Small membrane protein
SWP_RS16105	COG0583	DNA-binding transcription factor activity
SWP_RS16115	COG0301	tRNA thio-modification
SWP_RS16115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SWP_RS16125	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SWP_RS16135	COG1722	exodeoxyribonuclease VII activity
SWP_RS16140	COG0142	geranyltranstransferase activity
SWP_RS16145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SWP_RS16180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SWP_RS16185	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SWP_RS16200	COG0247	lactate metabolic process
SWP_RS16205	COG1139	Iron-sulfur cluster binding protein
SWP_RS16220	COG0523	cobalamin synthesis protein
SWP_RS16245	COG1595	DNA-templated transcription, initiation
SWP_RS16255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SWP_RS16265	COG0513	Belongs to the DEAD box helicase family
SWP_RS16295	COG0826	peptidase U32
SWP_RS16315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SWP_RS16335	COG1611	Belongs to the LOG family
SWP_RS16340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SWP_RS16350	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SWP_RS16365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SWP_RS16370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SWP_RS16375	COG0762	integral membrane protein
SWP_RS16390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SWP_RS16395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SWP_RS16420	COG3171	Protein conserved in bacteria
SWP_RS16425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SWP_RS16435	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
SWP_RS16445	COG3038	cytochrome b561
SWP_RS16480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SWP_RS16510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SWP_RS16515	COG2971	BadF BadG BcrA BcrD
SWP_RS16560	COG1609	Transcriptional regulator
SWP_RS16575	COG4968	Prepilin-type N-terminal cleavage methylation domain
SWP_RS16610	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SWP_RS16615	COG1047	Peptidyl-prolyl cis-trans
SWP_RS16620	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SWP_RS16625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SWP_RS16630	COG0196	riboflavin kinase activity
SWP_RS16635	COG0728	peptidoglycan biosynthetic process
SWP_RS16640	COG0268	Binds directly to 16S ribosomal RNA
SWP_RS16645	COG0640	Transcriptional regulator
SWP_RS16655	COG3022	response to hydroperoxide
SWP_RS16660	COG1115	amino acid carrier protein
SWP_RS16665	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SWP_RS16675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SWP_RS16680	COG0166	Belongs to the GPI family
SWP_RS16705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SWP_RS16710	COG0083	homoserine kinase activity
SWP_RS16715	COG0460	homoserine dehydrogenase
SWP_RS16715	COG0527	aspartate kinase activity
SWP_RS16730	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
SWP_RS16745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SWP_RS16750	COG0077	Prephenate dehydratase
SWP_RS16750	COG1605	Chorismate mutase
SWP_RS16765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SWP_RS16770	COG1151	hydroxylamine reductase activity
SWP_RS16775	COG1605	Chorismate mutase
SWP_RS16775	COG0287	Prephenate dehydrogenase
SWP_RS16780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SWP_RS16785	COG0335	large ribosomal subunit rRNA binding
SWP_RS16790	COG0336	Belongs to the RNA methyltransferase TrmD family
SWP_RS16795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SWP_RS16800	COG0228	four-way junction DNA binding
SWP_RS16810	COG4137	Cytochrome C assembly protein
SWP_RS16815	COG4536	flavin adenine dinucleotide binding
SWP_RS16830	COG0736	holo-[acyl-carrier-protein] synthase activity
SWP_RS16835	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SWP_RS16840	COG1381	Involved in DNA repair and RecF pathway recombination
SWP_RS16850	COG0571	ribonuclease III activity
SWP_RS16860	COG0481	GTPase activity
SWP_RS16870	COG3026	antisigma factor binding
SWP_RS16880	COG1595	DNA-templated transcription, initiation
SWP_RS16885	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SWP_RS16890	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
SWP_RS16895	COG0583	DNA-binding transcription factor activity
SWP_RS16905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SWP_RS16910	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SWP_RS16915	COG0730	response to heat
SWP_RS16925	COG0494	nUDIX hydrolase
SWP_RS16935	COG3066	DNA modification
SWP_RS16945	COG0583	DNA-binding transcription factor activity
SWP_RS16950	COG5002	protein histidine kinase activity
SWP_RS16950	COG0784	Response regulator, receiver
SWP_RS16950	COG2198	Histidine kinase
SWP_RS16955	COG1242	4 iron, 4 sulfur cluster binding
SWP_RS16960	COG0070	glutamate synthase
SWP_RS16960	COG0069	glutamate synthase activity
SWP_RS16960	COG0067	glutamate synthase
SWP_RS16965	COG0493	'glutamate synthase
SWP_RS16970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SWP_RS16990	COG1309	transcriptional regulator
SWP_RS17040	COG0454	-acetyltransferase
SWP_RS17075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SWP_RS17105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SWP_RS17110	COG0739	heme binding
SWP_RS17110	COG1196	nuclear chromosome segregation
SWP_RS17110	COG0741	lytic transglycosylase activity
SWP_RS17115	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SWP_RS17120	COG0745	RESPONSE REGULATOR receiver
SWP_RS17125	COG4206	TonB-dependent receptor
SWP_RS17130	COG1785	Belongs to the alkaline phosphatase family
SWP_RS17135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SWP_RS17150	COG0316	Belongs to the HesB IscA family
SWP_RS17200	COG2423	ornithine cyclodeaminase activity
SWP_RS17220	COG0583	DNA-binding transcription factor activity
SWP_RS17225	COG1404	Belongs to the peptidase S8 family
SWP_RS17235	COG3590	peptidase
SWP_RS17275	COG4807	Protein conserved in bacteria
SWP_RS17280	COG0281	malic enzyme
SWP_RS17300	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SWP_RS17305	COG3360	Dodecin
SWP_RS17310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SWP_RS17330	COG2890	protein-(glutamine-N5) methyltransferase activity
SWP_RS17335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SWP_RS17340	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SWP_RS17345	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
SWP_RS17350	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SWP_RS17355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SWP_RS17420	COG0193	aminoacyl-tRNA hydrolase activity
SWP_RS17425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SWP_RS17435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SWP_RS17440	COG1702	phosphate starvation-inducible protein PhoH
SWP_RS17445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SWP_RS17450	COG4535	Mg2 and Co2 transporter CorC
SWP_RS17455	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SWP_RS17470	COG0495	leucyl-tRNA aminoacylation
SWP_RS17475	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
SWP_RS17485	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SWP_RS17490	COG0799	negative regulation of ribosome biogenesis
SWP_RS17495	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SWP_RS17500	COG0768	penicillin binding
SWP_RS17505	COG0772	Belongs to the SEDS family
SWP_RS17510	COG2951	lytic endotransglycosylase activity
SWP_RS17515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SWP_RS17520	COG1686	Belongs to the peptidase S11 family
SWP_RS17525	COG2921	Belongs to the UPF0250 family
SWP_RS17530	COG0321	lipoyl(octanoyl) transferase activity
SWP_RS17535	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SWP_RS17585	COG0542	response to heat
SWP_RS17595	COG0564	pseudouridine synthase activity
SWP_RS17600	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SWP_RS17625	COG4206	TonB-dependent receptor
SWP_RS17645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SWP_RS17660	COG0004	ammonium transporteR
SWP_RS17665	COG0347	Belongs to the P(II) protein family
SWP_RS17675	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
SWP_RS17680	COG3850	Histidine kinase
SWP_RS17685	COG2197	response regulator
SWP_RS17695	COG3604	Transcriptional regulator
SWP_RS17700	COG0348	domain, Protein
SWP_RS17705	COG0318	PFAM AMP-dependent synthetase and ligase
SWP_RS17725	COG2165	general secretion pathway protein
SWP_RS17735	COG3040	lipid binding
SWP_RS17740	COG1132	(ABC) transporter
SWP_RS17745	COG0748	coenzyme F420 binding
SWP_RS17750	COG3721	Heme iron utilization protein
SWP_RS17755	COG4771	TonB-dependent receptor
SWP_RS17765	COG0811	peptide transport
SWP_RS17770	COG0848	biopolymer transport protein
SWP_RS17775	COG4558	Periplasmic binding protein
SWP_RS17780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SWP_RS17785	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SWP_RS17810	COG3005	denitrification pathway
SWP_RS17820	COG3381	protein complex oligomerization
SWP_RS17845	COG2314	TM2 domain
SWP_RS17855	COG0745	RESPONSE REGULATOR receiver
SWP_RS17860	COG2205	protein histidine kinase activity
SWP_RS17875	COG3655	Transcriptional regulator
SWP_RS17920	COG1252	NADH dehydrogenase
SWP_RS17930	COG2207	Transcriptional regulator
SWP_RS17950	COG4206	TonB-dependent receptor
SWP_RS17955	COG1757	Na H antiporter
SWP_RS17970	COG3036	rescue of stalled ribosome
SWP_RS17990	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SWP_RS18000	COG1741	Belongs to the pirin family
SWP_RS18020	COG0583	DNA-binding transcription factor activity
SWP_RS18025	COG2203	Gaf domain
SWP_RS18025	COG4251	negative regulation of phosphorylation
SWP_RS18025	COG5001	Diguanylate cyclase
SWP_RS18025	COG3706	GGDEF domain
SWP_RS18050	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
SWP_RS18060	COG3487	Iron-regulated protein
SWP_RS18095	COG0529	Catalyzes the synthesis of activated sulfate
SWP_RS18100	COG3273	potassium ion transport
SWP_RS18100	COG0471	metal ion transport
SWP_RS18105	COG2895	sulfate adenylyltransferase (ATP) activity
SWP_RS18110	COG0175	sulfate reduction
SWP_RS18115	COG1648	precorrin-2 dehydrogenase activity
SWP_RS18115	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SWP_RS18120	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
SWP_RS18135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SWP_RS18140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SWP_RS18145	COG2165	general secretion pathway protein
SWP_RS18170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SWP_RS18175	COG1566	PFAM secretion protein HlyD family protein
SWP_RS18185	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SWP_RS18190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SWP_RS18200	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SWP_RS18205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SWP_RS18225	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SWP_RS18230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SWP_RS18235	COG2967	ApaG domain
SWP_RS18240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SWP_RS18260	COG3610	response to peptide
SWP_RS18265	COG2966	Psort location CytoplasmicMembrane, score
SWP_RS18270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SWP_RS18275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SWP_RS18280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SWP_RS18285	COG0142	geranyltranstransferase activity
SWP_RS18290	COG0039	L-malate dehydrogenase activity
SWP_RS18295	COG1438	arginine binding
SWP_RS18305	COG2837	iron assimilation
SWP_RS18315	COG1178	ABC-type Fe3 transport system permease component
SWP_RS18320	COG1840	ABC-type Fe3 transport system, periplasmic component
SWP_RS18330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SWP_RS18350	COG5265	(ABC) transporter
SWP_RS18355	COG3301	Polysulphide reductase, NrfD
SWP_RS18360	COG0437	4 iron, 4 sulfur cluster binding
SWP_RS18375	COG0583	DNA-binding transcription factor activity
SWP_RS18390	COG0583	DNA-binding transcription factor activity
SWP_RS18410	COG1187	pseudouridine synthase activity
SWP_RS18420	COG0418	dihydroorotase activity
SWP_RS18445	COG0189	ligase activity
SWP_RS18475	COG1858	cytochrome C peroxidase
SWP_RS18480	COG2010	Cytochrome c
SWP_RS18490	COG3278	Belongs to the heme-copper respiratory oxidase family
SWP_RS18515	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SWP_RS18530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SWP_RS18535	COG1177	transmembrane transport
SWP_RS18540	COG1176	ABC-type spermidine putrescine transport system, permease component I
SWP_RS18545	COG3842	ATPase activity
SWP_RS18555	COG0174	glutamine synthetase
SWP_RS18560	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SWP_RS18570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SWP_RS18580	COG1506	peptidase
SWP_RS18585	COG1247	-acetyltransferase
SWP_RS18595	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SWP_RS18615	COG3209	COG3209 Rhs family protein
SWP_RS18630	COG3209	COG3209 Rhs family protein
SWP_RS18640	COG1012	belongs to the aldehyde dehydrogenase family
SWP_RS18645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SWP_RS18715	COG0545	Peptidyl-prolyl cis-trans isomerase
SWP_RS18725	COG1940	carbohydrate kinase activity
SWP_RS18730	COG2814	Major facilitator Superfamily
SWP_RS18735	COG0006	proline dipeptidase activity
SWP_RS18745	COG0513	Belongs to the DEAD box helicase family
SWP_RS18760	COG1404	Belongs to the peptidase S8 family
SWP_RS18765	COG2268	Band 7 protein
SWP_RS18800	COG0795	lipopolysaccharide-transporting ATPase activity
SWP_RS18805	COG0795	lipopolysaccharide-transporting ATPase activity
SWP_RS18810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SWP_RS18840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SWP_RS18845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SWP_RS18850	COG4974	Belongs to the 'phage' integrase family
SWP_RS18860	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SWP_RS18865	COG0513	Belongs to the DEAD box helicase family
SWP_RS18870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS18915	COG0191	fructose-bisphosphate aldolase activity
SWP_RS18920	COG0126	phosphoglycerate kinase activity
SWP_RS18925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SWP_RS18930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SWP_RS18935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SWP_RS18995	COG1301	dicarboxylic acid transport
SWP_RS19010	COG1760	l-serine dehydratase
SWP_RS19015	COG0814	amino acid
SWP_RS19025	COG0456	acetyltransferase
SWP_RS19030	COG0667	Aldo Keto reductase
SWP_RS19040	COG2166	iron-sulfur cluster assembly
SWP_RS19050	COG2358	TRAP transporter, solute receptor (TAXI family
SWP_RS19060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SWP_RS19075	COG0826	peptidase U32
SWP_RS19095	COG3604	Transcriptional regulator
SWP_RS19110	COG1017	nitric oxide dioxygenase activity
SWP_RS19110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SWP_RS19130	COG0363	glucosamine-6-phosphate deaminase activity
SWP_RS19135	COG1187	pseudouridine synthase activity
SWP_RS19155	COG3265	gluconokinase activity
SWP_RS19160	COG3459	Glycosyltransferase 36 associated
SWP_RS19165	COG2211	Major facilitator Superfamily
SWP_RS19175	COG0583	DNA-binding transcription factor activity
SWP_RS19190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SWP_RS19195	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SWP_RS19210	COG2801	Transposase and inactivated derivatives
SWP_RS19215	COG2963	transposase activity
SWP_RS19250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SWP_RS19255	COG1846	Transcriptional regulator
SWP_RS19260	COG1764	response to oxidative stress
SWP_RS19285	COG3634	alkyl hydroperoxide reductase activity
SWP_RS19310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SWP_RS19340	COG0564	pseudouridine synthase activity
SWP_RS19345	COG1522	sequence-specific DNA binding
SWP_RS19365	COG0527	aspartate kinase activity
SWP_RS19375	COG0745	RESPONSE REGULATOR receiver
SWP_RS19385	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SWP_RS19395	COG0583	DNA-binding transcription factor activity
SWP_RS19400	COG1053	succinate dehydrogenase
SWP_RS19405	COG4191	Histidine kinase
SWP_RS19405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SWP_RS19410	COG2204	response regulator
SWP_RS19415	COG1301	dicarboxylic acid transport
SWP_RS19440	COG1115	amino acid carrier protein
SWP_RS19465	COG1028	Short-chain dehydrogenase reductase Sdr
SWP_RS19475	COG1730	sister chromatid segregation
SWP_RS19510	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SWP_RS19525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SWP_RS19530	COG1643	Atp-dependent helicase
SWP_RS19555	COG1489	DNA binding
SWP_RS19565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SWP_RS19575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SWP_RS19580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SWP_RS19585	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SWP_RS19605	COG0842	Transport permease protein
SWP_RS19610	COG1131	(ABC) transporter
SWP_RS19620	COG0163	prenyltransferase activity
SWP_RS19625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SWP_RS19635	COG0659	secondary active sulfate transmembrane transporter activity
SWP_RS19640	COG0589	response to stress
SWP_RS19645	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SWP_RS19650	COG0778	Nitroreductase
SWP_RS19670	COG3706	GGDEF domain
SWP_RS19675	COG2873	o-acetylhomoserine
SWP_RS19685	COG1757	Na H antiporter
SWP_RS19690	COG3706	GGDEF domain
SWP_RS19695	COG0823	Involved in the tonB-independent uptake of proteins
SWP_RS19695	COG1506	peptidase
SWP_RS19710	COG1187	pseudouridine synthase activity
SWP_RS19735	COG0814	amino acid
SWP_RS19740	COG2119	membrane
SWP_RS19755	COG2050	protein possibly involved in aromatic compounds catabolism
SWP_RS19760	COG0813	purine-nucleoside phosphorylase activity
SWP_RS19765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SWP_RS19775	COG0737	Belongs to the 5'-nucleotidase family
SWP_RS19805	COG3647	Membrane
SWP_RS19810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SWP_RS19815	COG0354	folic acid binding
SWP_RS19825	COG2205	protein histidine kinase activity
SWP_RS19825	COG5002	protein histidine kinase activity
SWP_RS19825	COG0784	Response regulator, receiver
SWP_RS19835	COG0577	efflux transmembrane transporter activity
SWP_RS19850	COG0243	molybdopterin cofactor binding
SWP_RS19855	COG3043	anaerobic respiration
SWP_RS19875	COG1280	lysine exporter protein (LysE YggA)
SWP_RS19885	COG0583	DNA-binding transcription factor activity
SWP_RS19895	COG0439	Biotin carboxylase
SWP_RS19900	COG0583	DNA-binding transcription factor activity
SWP_RS19915	COG3091	SprT-like family
SWP_RS19925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SWP_RS19930	COG0189	ligase activity
SWP_RS19935	COG1785	Belongs to the alkaline phosphatase family
SWP_RS19940	COG2813	Specifically methylates the guanine in position
SWP_RS20000	COG2963	transposase activity
SWP_RS20035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SWP_RS20065	COG0270	DNA (cytosine-5-)-methyltransferase activity
SWP_RS20085	COG0326	Molecular chaperone. Has ATPase activity
SWP_RS20100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SWP_RS20115	COG0500	methyltransferase
SWP_RS20135	COG1324	tolerance protein
SWP_RS20140	COG4232	protein-disulfide reductase activity
SWP_RS20145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SWP_RS20145	COG4651	solute:proton antiporter activity
SWP_RS20150	COG3250	beta-galactosidase activity
SWP_RS20155	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SWP_RS20160	COG1085	galactose-1-phosphate uridylyltransferase
SWP_RS20165	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SWP_RS20170	COG2017	converts alpha-aldose to the beta-anomer
SWP_RS20185	COG0629	single-stranded DNA binding
SWP_RS20245	COG2814	Major facilitator Superfamily
SWP_RS20250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SWP_RS20260	COG2234	aminopeptidase activity
SWP_RS20280	COG3258	Cytochrome c
SWP_RS20290	COG0527	aspartate kinase activity
SWP_RS20290	COG0460	homoserine dehydrogenase
SWP_RS20295	COG0626	cystathionine gamma-synthase activity
SWP_RS20300	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
SWP_RS20320	COG0673	inositol 2-dehydrogenase activity
SWP_RS20365	COG0583	DNA-binding transcription factor activity
SWP_RS20370	COG4221	oxidoreductase activity
SWP_RS20390	COG4988	ABC transporter
SWP_RS20395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SWP_RS20400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS20420	COG1902	pentaerythritol trinitrate reductase activity
SWP_RS20445	COG2199	diguanylate cyclase activity
SWP_RS20445	COG2203	Gaf domain
SWP_RS20470	COG0564	pseudouridine synthase activity
SWP_RS20490	COG2731	YhcH YjgK YiaL family protein
SWP_RS20500	COG1104	cysteine desulfurase activity
SWP_RS20505	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
SWP_RS20510	COG2205	protein histidine kinase activity
SWP_RS20510	COG0784	Response regulator, receiver
SWP_RS20515	COG1858	cytochrome C peroxidase
SWP_RS20560	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SWP_RS20570	COG4221	oxidoreductase activity
SWP_RS20590	COG3708	Transcriptional regulator
SWP_RS20590	COG2207	Transcriptional regulator
SWP_RS20605	COG4977	sequence-specific DNA binding
SWP_RS20605	COG1917	Cupin 2, conserved barrel domain protein
SWP_RS20625	COG0681	Belongs to the peptidase S26 family
SWP_RS20670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SWP_RS20705	COG3301	Polysulphide reductase, NrfD
SWP_RS20710	COG0437	4 iron, 4 sulfur cluster binding
SWP_RS20720	COG0545	Peptidyl-prolyl cis-trans isomerase
SWP_RS20730	COG0484	heat shock protein binding
SWP_RS20735	COG1138	Cytochrome C-type biogenesis protein
SWP_RS20740	COG3088	subunit of a heme lyase
SWP_RS20740	COG4235	cytochrome complex assembly
SWP_RS20755	COG1757	Na H antiporter
SWP_RS20780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SWP_RS20820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SWP_RS20830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SWP_RS20885	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SWP_RS20890	COG0210	DNA helicase
SWP_RS20895	COG0251	oxidation-reduction process
SWP_RS20905	COG0494	nUDIX hydrolase
SWP_RS20910	COG0330	HflC and HflK could
SWP_RS20915	COG0330	HflC and HflK could
SWP_RS20930	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SWP_RS20935	COG2841	Protein conserved in bacteria
SWP_RS20945	COG0668	transmembrane transport
SWP_RS20955	COG2153	protein acetylation
SWP_RS20980	COG0583	DNA-binding transcription factor activity
SWP_RS20985	COG0217	transcriptional regulatory protein
SWP_RS20990	COG3011	Protein conserved in bacteria
SWP_RS21005	COG0789	Transcriptional regulator
SWP_RS21010	COG0138	bifunctional purine biosynthesis protein purh
SWP_RS21015	COG0151	Belongs to the GarS family
SWP_RS21040	COG0745	RESPONSE REGULATOR receiver
SWP_RS21045	COG5002	protein histidine kinase activity
SWP_RS21055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SWP_RS21065	COG1049	propionate catabolic process, 2-methylcitrate cycle
SWP_RS21070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SWP_RS21080	COG3344	reverse transcriptase
SWP_RS21085	COG3590	peptidase
SWP_RS21090	COG1752	Esterase of the alpha-beta hydrolase superfamily
SWP_RS21100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SWP_RS21105	COG0508	dehydrogenase complex catalyzes the overall conversion of
SWP_RS21110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SWP_RS21115	COG2186	Transcriptional regulator
SWP_RS21140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SWP_RS21145	COG1459	type II secretion system
SWP_RS21150	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SWP_RS21155	COG0237	dephospho-CoA kinase activity
SWP_RS21165	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
SWP_RS21170	COG0494	nUDIX hydrolase
SWP_RS21180	COG0612	Peptidase, M16
SWP_RS21265	COG0531	amino acid
SWP_RS21270	COG1522	sequence-specific DNA binding
SWP_RS21275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SWP_RS21280	COG0596	Alpha beta hydrolase
SWP_RS21285	COG1441	menaquinone biosynthetic process
SWP_RS21305	COG2177	Part of the ABC transporter FtsEX involved in
SWP_RS21310	COG2884	Cell division ATP-binding protein ftsE
SWP_RS21315	COG0552	protein localization to endoplasmic reticulum
SWP_RS21320	COG0742	ribosomal rna small subunit methyltransferase
SWP_RS21330	COG3005	denitrification pathway
SWP_RS21360	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SWP_RS21370	COG3706	GGDEF domain
SWP_RS21375	COG1566	PFAM secretion protein HlyD family protein
SWP_RS21390	COG0814	amino acid
SWP_RS21395	COG2937	Belongs to the GPAT DAPAT family
SWP_RS21400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SWP_RS21410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SWP_RS21415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SWP_RS21420	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
SWP_RS21445	COG1612	heme a metabolic process
SWP_RS21450	COG0109	protoheme IX farnesyltransferase activity
SWP_RS21455	COG1999	signal sequence binding
SWP_RS21470	COG0534	Mate efflux family protein
SWP_RS21475	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SWP_RS21475	COG0316	Belongs to the HesB IscA family
SWP_RS21485	COG1040	competence protein
SWP_RS21490	COG0596	Alpha beta hydrolase
SWP_RS21500	COG1368	sulfuric ester hydrolase activity
SWP_RS21505	COG2183	response to ionizing radiation
SWP_RS21510	COG3710	Transcriptional regulator
SWP_RS21520	COG3291	Pkd domain containing protein
SWP_RS21530	COG1404	Belongs to the peptidase S8 family
SWP_RS21535	COG1770	oligopeptidase
SWP_RS21550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SWP_RS21585	COG0678	peroxiredoxin activity
SWP_RS21605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SWP_RS21610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SWP_RS21615	COG0671	phosphoesterase, PA-phosphatase related
SWP_RS21650	COG0346	lactoylglutathione lyase activity
SWP_RS21655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SWP_RS21670	COG3291	Pkd domain containing protein
SWP_RS21690	COG0742	ribosomal rna small subunit methyltransferase
SWP_RS21700	COG3291	Pkd domain containing protein
SWP_RS21705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
SWP_RS21720	COG0583	DNA-binding transcription factor activity
SWP_RS21725	COG0534	Mate efflux family protein
SWP_RS21730	COG1196	nuclear chromosome segregation
SWP_RS21730	COG0739	heme binding
SWP_RS21730	COG0741	lytic transglycosylase activity
SWP_RS21740	COG1704	LemA family
SWP_RS21745	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SWP_RS21750	COG3344	reverse transcriptase
SWP_RS21780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SWP_RS21785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SWP_RS21820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SWP_RS21825	COG0583	DNA-binding transcription factor activity
SWP_RS21830	COG0657	acetylesterase activity
SWP_RS21880	COG0644	oxidoreductase
SWP_RS21885	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SWP_RS21890	COG2271	Major facilitator Superfamily
SWP_RS21915	COG0848	biopolymer transport protein
SWP_RS21935	COG4178	(ABC) transporter
SWP_RS21940	COG0612	Peptidase, M16
SWP_RS21955	COG2855	membrane
SWP_RS21990	COG1122	ATPase activity
SWP_RS22000	COG1169	isochorismate synthase
SWP_RS22005	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SWP_RS22015	COG3852	Histidine kinase
SWP_RS22020	COG2204	response regulator
SWP_RS22035	COG3842	ATPase activity
SWP_RS22040	COG0746	molybdenum cofactor guanylyltransferase activity
SWP_RS22045	COG0303	'Molybdopterin
SWP_RS22050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SWP_RS22065	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SWP_RS22075	COG0519	Catalyzes the synthesis of GMP from XMP
SWP_RS22090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SWP_RS22105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SWP_RS22110	COG0564	pseudouridine synthase activity
SWP_RS22115	COG2205	protein histidine kinase activity
SWP_RS22120	COG0745	RESPONSE REGULATOR receiver
SWP_RS22130	COG3111	PFAM Bacterial OB fold (BOF) protein
SWP_RS22135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SWP_RS22150	COG0314	molybdopterin synthase activity
SWP_RS22155	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SWP_RS22160	COG0315	cyclic pyranopterin monophosphate synthase activity
SWP_RS22165	COG0521	Mo-molybdopterin cofactor biosynthetic process
SWP_RS22170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SWP_RS22180	COG0840	transmembrane signaling receptor activity
SWP_RS22190	COG2258	MOSC domain
SWP_RS22225	COG0641	radical SAM
SWP_RS22245	COG0437	4 iron, 4 sulfur cluster binding
SWP_RS22250	COG3383	formate dehydrogenase (NAD+) activity
SWP_RS22250	COG0243	molybdopterin cofactor binding
SWP_RS22265	COG0437	4 iron, 4 sulfur cluster binding
SWP_RS22270	COG0243	molybdopterin cofactor binding
SWP_RS22270	COG3383	formate dehydrogenase (NAD+) activity
SWP_RS22320	COG1580	Controls the rotational direction of flagella during chemotaxis
SWP_RS22325	COG3161	chorismate lyase activity
SWP_RS22335	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SWP_RS22335	COG3408	Glycogen debranching enzyme
SWP_RS22340	COG2095	MarC family integral membrane protein
SWP_RS22370	COG0786	glutamate:sodium symporter activity
SWP_RS22375	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SWP_RS22375	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SWP_RS22380	COG0859	PFAM glycosyl transferase family 9
SWP_RS22385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SWP_RS22415	COG0859	PFAM glycosyl transferase family 9
SWP_RS22420	COG3642	lipopolysaccharide core region biosynthetic process
SWP_RS22425	COG1519	Transferase
SWP_RS22450	COG1063	alcohol dehydrogenase
SWP_RS22455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SWP_RS22460	COG0705	Rhomboid family
SWP_RS22470	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
SWP_RS22475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SWP_RS22475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SWP_RS22480	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SWP_RS22495	COG3078	GTPase activator activity
SWP_RS22505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SWP_RS22515	COG2267	carboxylic ester hydrolase activity
SWP_RS22525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SWP_RS22530	COG1684	flagellar biosynthetic protein fliR
SWP_RS22545	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SWP_RS22570	COG1766	The M ring may be actively involved in energy transduction
SWP_RS22600	COG1595	DNA-templated transcription, initiation
SWP_RS22630	COG1815	bacterial-type flagellum-dependent cell motility
SWP_RS22640	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SWP_RS22650	COG4786	Flagellar basal body rod
SWP_RS22655	COG4786	Flagellar basal body rod
SWP_RS22660	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
SWP_RS22665	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
SWP_RS22670	COG1706	bacterial-type flagellum-dependent cell motility
SWP_RS22675	COG1705	Flagellar rod assembly protein muramidase FlgJ
SWP_RS22675	COG3951	Flagellar rod assembly protein muramidase FlgJ
SWP_RS22680	COG1256	bacterial-type flagellum assembly
SWP_RS22685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SWP_RS22700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SWP_RS22705	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SWP_RS22730	COG1191	sigma factor activity
SWP_RS22735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SWP_RS22740	COG1360	Flagellar Motor Protein
SWP_RS22820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SWP_RS22830	COG0581	inorganic phosphate transmembrane transporter activity
SWP_RS22835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SWP_RS22850	COG4206	TonB-dependent receptor
SWP_RS22855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SWP_RS22860	COG1349	DNA-binding transcription factor activity
SWP_RS22865	COG4774	siderophore transport
SWP_RS22870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SWP_RS22880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SWP_RS22885	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SWP_RS22890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SWP_RS22895	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SWP_RS22900	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SWP_RS22905	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SWP_RS22915	COG0356	it plays a direct role in the translocation of protons across the membrane
SWP_RS22920	COG3312	ion transport
SWP_RS22925	COG1475	DNA binding
SWP_RS22930	COG1192	Involved in chromosome partitioning
SWP_RS22935	COG0357	Ribosomal RNA small subunit methyltransferase G
SWP_RS22940	COG0445	tRNA wobble uridine modification
SWP_RS22960	COG2165	general secretion pathway protein
SWP_RS23005	COG2205	protein histidine kinase activity
SWP_RS23005	COG0784	Response regulator, receiver
SWP_RS23005	COG5002	protein histidine kinase activity
SWP_RS23050	COG3291	Pkd domain containing protein
SWP_RS23090	COG1620	l-lactate permease
SWP_RS23120	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SWP_RS23135	COG0811	peptide transport
SWP_RS23195	COG2165	general secretion pathway protein
SWP_RS23210	COG3209	COG3209 Rhs family protein
SWP_RS23230	COG2165	general secretion pathway protein
SWP_RS23235	COG2356	endonuclease I
SWP_RS23240	COG0811	peptide transport
SWP_RS23260	COG4890	Cyd operon protein YbgT