locus-tag	class	description
FM037_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FM037_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FM037_RS00020	COG0187	DNA topoisomerase II activity
FM037_RS00050	COG1984	allophanate hydrolase subunit 2
FM037_RS00055	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FM037_RS00065	COG0751	glycine-tRNA ligase activity
FM037_RS00070	COG0752	glycyl-tRNA synthetase alpha subunit
FM037_RS00075	COG2818	Glycosylase
FM037_RS00095	COG0425	Belongs to the sulfur carrier protein TusA family
FM037_RS00100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FM037_RS00110	COG0183	Belongs to the thiolase family
FM037_RS00115	COG1024	Enoyl-CoA hydratase
FM037_RS00115	COG1250	3-hydroxyacyl-CoA dehydrogenase
FM037_RS00120	COG0006	proline dipeptidase activity
FM037_RS00125	COG1739	Uncharacterized protein family UPF0029
FM037_RS00135	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FM037_RS00150	COG0640	Transcriptional regulator
FM037_RS00170	COG0569	domain protein
FM037_RS00175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FM037_RS00175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FM037_RS00180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FM037_RS00185	COG0242	peptide deformylase activity
FM037_RS00195	COG0758	DNA mediated transformation
FM037_RS00200	COG2922	Belongs to the Smg family
FM037_RS00205	COG3291	Pkd domain containing protein
FM037_RS00215	COG0009	L-threonylcarbamoyladenylate synthase
FM037_RS00220	COG0408	coproporphyrinogen oxidase activity
FM037_RS00225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FM037_RS00235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FM037_RS00270	COG1360	Flagellar Motor Protein
FM037_RS00275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FM037_RS00280	COG1191	sigma factor activity
FM037_RS00285	COG1580	Controls the rotational direction of flagella during chemotaxis
FM037_RS00305	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FM037_RS00310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FM037_RS00335	COG3951	Flagellar rod assembly protein muramidase FlgJ
FM037_RS00335	COG1705	Flagellar rod assembly protein muramidase FlgJ
FM037_RS00340	COG1706	bacterial-type flagellum-dependent cell motility
FM037_RS00345	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FM037_RS00350	COG4786	Flagellar basal body rod
FM037_RS00355	COG4787	bacterial-type flagellum-dependent cell motility
FM037_RS00360	COG1749	Flagellar hook protein flgE
FM037_RS00365	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FM037_RS00370	COG1558	bacterial-type flagellum-dependent cell motility
FM037_RS00375	COG1815	bacterial-type flagellum-dependent cell motility
FM037_RS00440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FM037_RS00460	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FM037_RS00470	COG2267	carboxylic ester hydrolase activity
FM037_RS00480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FM037_RS00490	COG3078	GTPase activator activity
FM037_RS00505	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FM037_RS00510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FM037_RS00510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FM037_RS00515	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FM037_RS00520	COG0705	Rhomboid family
FM037_RS00525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM037_RS00530	COG1063	alcohol dehydrogenase
FM037_RS00545	COG1519	Transferase
FM037_RS00550	COG3642	lipopolysaccharide core region biosynthetic process
FM037_RS00555	COG1091	dTDP-4-dehydrorhamnose reductase activity
FM037_RS00570	COG0859	PFAM glycosyl transferase family 9
FM037_RS00625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FM037_RS00640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FM037_RS00655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FM037_RS00660	COG0303	'Molybdopterin
FM037_RS00665	COG0746	molybdenum cofactor guanylyltransferase activity
FM037_RS00670	COG1136	(ABC) transporter
FM037_RS00685	COG2204	response regulator
FM037_RS00690	COG3852	Histidine kinase
FM037_RS00695	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FM037_RS00705	COG1169	isochorismate synthase
FM037_RS00720	COG2205	protein histidine kinase activity
FM037_RS00720	COG5002	protein histidine kinase activity
FM037_RS00720	COG0784	Response regulator, receiver
FM037_RS00725	COG2855	membrane
FM037_RS00745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FM037_RS00760	COG0339	signal peptide processing
FM037_RS00795	COG2814	Major facilitator Superfamily
FM037_RS00810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS00815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM037_RS00835	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FM037_RS00840	COG1704	LemA family
FM037_RS00850	COG1196	nuclear chromosome segregation
FM037_RS00850	COG0739	heme binding
FM037_RS00850	COG0741	lytic transglycosylase activity
FM037_RS00860	COG0583	DNA-binding transcription factor activity
FM037_RS00870	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FM037_RS00875	COG0742	ribosomal rna small subunit methyltransferase
FM037_RS00885	COG1566	PFAM secretion protein HlyD family protein
FM037_RS00890	COG0678	peroxiredoxin activity
FM037_RS00900	COG0840	transmembrane signaling receptor activity
FM037_RS00915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FM037_RS00930	COG2183	response to ionizing radiation
FM037_RS00945	COG0596	Alpha beta hydrolase
FM037_RS00950	COG1040	competence protein
FM037_RS00960	COG0316	Belongs to the HesB IscA family
FM037_RS00960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FM037_RS00965	COG0534	Mate efflux family protein
FM037_RS00970	COG0726	polysaccharide deacetylase
FM037_RS00975	COG2201	protein-glutamate methylesterase activity
FM037_RS00980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FM037_RS00985	COG0840	transmembrane signaling receptor activity
FM037_RS00990	COG0835	chemotaxis
FM037_RS00995	COG0643	Histidine kinase
FM037_RS00995	COG2198	Histidine kinase
FM037_RS01000	COG0745	RESPONSE REGULATOR receiver
FM037_RS01015	COG0109	protoheme IX farnesyltransferase activity
FM037_RS01020	COG1612	heme a metabolic process
FM037_RS01045	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FM037_RS01050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FM037_RS01055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FM037_RS01060	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
FM037_RS01065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FM037_RS01070	COG2937	Belongs to the GPAT DAPAT family
FM037_RS01075	COG0814	amino acid
FM037_RS01080	COG0778	Nitroreductase
FM037_RS01095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS01105	COG1017	nitric oxide dioxygenase activity
FM037_RS01105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FM037_RS01125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS01150	COG3005	denitrification pathway
FM037_RS01155	COG2207	Transcriptional regulator
FM037_RS01155	COG3708	Transcriptional regulator
FM037_RS01170	COG1120	ATPase activity
FM037_RS01175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FM037_RS01190	COG0742	ribosomal rna small subunit methyltransferase
FM037_RS01195	COG0552	protein localization to endoplasmic reticulum
FM037_RS01200	COG2884	Cell division ATP-binding protein ftsE
FM037_RS01205	COG2177	Part of the ABC transporter FtsEX involved in
FM037_RS01220	COG0318	PFAM AMP-dependent synthetase and ligase
FM037_RS01230	COG0596	Alpha beta hydrolase
FM037_RS01235	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FM037_RS01250	COG0243	molybdopterin cofactor binding
FM037_RS01255	COG0437	4 iron, 4 sulfur cluster binding
FM037_RS01260	COG3381	protein complex oligomerization
FM037_RS01270	COG1522	sequence-specific DNA binding
FM037_RS01330	COG1716	ATPase activity
FM037_RS01330	COG5001	Diguanylate cyclase
FM037_RS01350	COG0612	Peptidase, M16
FM037_RS01370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FM037_RS01380	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FM037_RS01385	COG1328	CTP reductase activity
FM037_RS01395	COG3284	Transcriptional regulator
FM037_RS01400	COG0753	catalase activity
FM037_RS01405	COG3568	Endonuclease Exonuclease Phosphatase
FM037_RS01420	COG0604	alcohol dehydrogenase
FM037_RS01430	COG1053	succinate dehydrogenase
FM037_RS01445	COG0583	DNA-binding transcription factor activity
FM037_RS01455	COG2205	protein histidine kinase activity
FM037_RS01460	COG0745	RESPONSE REGULATOR receiver
FM037_RS01465	COG3678	ATP-independent chaperone mediated protein folding
FM037_RS01505	COG1058	Belongs to the CinA family
FM037_RS01505	COG1546	Belongs to the CinA family
FM037_RS01515	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FM037_RS01520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FM037_RS01525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FM037_RS01530	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FM037_RS01535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FM037_RS01545	COG0165	Argininosuccinate lyase
FM037_RS01550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FM037_RS01580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FM037_RS01595	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FM037_RS01610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FM037_RS01615	COG0546	phosphoglycolate phosphatase activity
FM037_RS01620	COG0180	Tryptophanyl-tRNA synthetase
FM037_RS01625	COG0583	DNA-binding transcription factor activity
FM037_RS01635	COG2823	Periplasmic or secreted lipoprotein
FM037_RS01640	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FM037_RS01645	COG0792	nuclease activity
FM037_RS01655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FM037_RS01665	COG4175	Glycine betaine
FM037_RS01665	COG3448	diguanylate cyclase activity
FM037_RS01670	COG4176	ABC-type proline glycine betaine transport system permease component
FM037_RS01680	COG0494	nUDIX hydrolase
FM037_RS01685	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FM037_RS01695	COG0237	dephospho-CoA kinase activity
FM037_RS01700	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FM037_RS01705	COG1459	type II secretion system
FM037_RS01710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FM037_RS01740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FM037_RS01745	COG0508	dehydrogenase complex catalyzes the overall conversion of
FM037_RS01750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FM037_RS01760	COG1752	Esterase of the alpha-beta hydrolase superfamily
FM037_RS01765	COG3590	peptidase
FM037_RS01770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FM037_RS01775	COG1049	propionate catabolic process, 2-methylcitrate cycle
FM037_RS01785	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FM037_RS01790	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FM037_RS01800	COG0018	arginyl-trna synthetase
FM037_RS01805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FM037_RS01815	COG0254	rRNA binding
FM037_RS01825	COG0281	malic enzyme
FM037_RS01830	COG2199	diguanylate cyclase activity
FM037_RS01830	COG2200	EAL domain
FM037_RS01860	COG3409	Peptidoglycan-binding domain 1 protein
FM037_RS01860	COG3267	Type II secretory pathway component ExeA
FM037_RS01870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FM037_RS01875	COG1459	type II secretion system
FM037_RS01885	COG2165	general secretion pathway protein
FM037_RS01890	COG2165	general secretion pathway protein
FM037_RS01895	COG2165	general secretion pathway protein
FM037_RS01900	COG2165	general secretion pathway protein
FM037_RS01935	COG1792	Involved in formation and maintenance of cell shape
FM037_RS01940	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FM037_RS01950	COG1530	ribonuclease E activity
FM037_RS01955	COG3164	Protein of unknown function
FM037_RS01960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FM037_RS01965	COG0312	modulator of DNA gyrase
FM037_RS01975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS02000	COG0312	modulator of DNA gyrase
FM037_RS02005	COG0640	Transcriptional regulator
FM037_RS02010	COG0798	PFAM Bile acid sodium symporter
FM037_RS02015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FM037_RS02025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FM037_RS02055	COG1115	amino acid carrier protein
FM037_RS02060	COG0842	Transport permease protein
FM037_RS02070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS02085	COG0745	RESPONSE REGULATOR receiver
FM037_RS02130	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FM037_RS02140	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FM037_RS02145	COG0668	transmembrane transport
FM037_RS02175	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FM037_RS02180	COG3706	GGDEF domain
FM037_RS02185	COG2201	protein-glutamate methylesterase activity
FM037_RS02190	COG1024	Enoyl-CoA hydratase
FM037_RS02200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FM037_RS02205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FM037_RS02210	COG2205	protein histidine kinase activity
FM037_RS02210	COG3437	response regulator, receiver
FM037_RS02210	COG3850	Histidine kinase
FM037_RS02210	COG4999	Histidine kinase
FM037_RS02250	COG0583	DNA-binding transcription factor activity
FM037_RS02275	COG0534	Mate efflux family protein
FM037_RS02280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FM037_RS02285	COG0459	protein refolding
FM037_RS02330	COG4221	oxidoreductase activity
FM037_RS02385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FM037_RS02400	COG2197	response regulator
FM037_RS02405	COG3850	Histidine kinase
FM037_RS02410	COG2223	nitrite transmembrane transporter activity
FM037_RS02420	COG1140	nitrate reductase beta subunit
FM037_RS02425	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FM037_RS02430	COG2181	nitrate reductase activity
FM037_RS02450	COG0702	epimerase
FM037_RS02510	COG2703	oxygen carrier activity
FM037_RS02515	COG0437	4 iron, 4 sulfur cluster binding
FM037_RS02535	COG0437	4 iron, 4 sulfur cluster binding
FM037_RS02540	COG0243	molybdopterin cofactor binding
FM037_RS02550	COG3123	guanosine phosphorylase activity
FM037_RS02560	COG1846	Transcriptional regulator
FM037_RS02590	COG3682	Transcriptional regulator
FM037_RS02600	COG0477	Major facilitator Superfamily
FM037_RS02630	COG0116	Belongs to the methyltransferase superfamily
FM037_RS02630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FM037_RS02640	COG2962	Rard protein
FM037_RS02680	COG5002	protein histidine kinase activity
FM037_RS02680	COG3850	Histidine kinase
FM037_RS02690	COG2885	chlorophyll binding
FM037_RS02700	COG2239	Acts as a magnesium transporter
FM037_RS02705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FM037_RS02715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FM037_RS02730	COG1137	ATPase activity
FM037_RS02745	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FM037_RS02750	COG0517	IMP dehydrogenase activity
FM037_RS02750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FM037_RS02760	COG1127	ABC transporter
FM037_RS02765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FM037_RS02770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FM037_RS02775	COG2854	intermembrane phospholipid transfer
FM037_RS02780	COG3113	response to antibiotic
FM037_RS02785	COG5007	Belongs to the BolA IbaG family
FM037_RS02790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FM037_RS02795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FM037_RS02800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FM037_RS02815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FM037_RS02820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FM037_RS02825	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FM037_RS02835	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FM037_RS02840	COG0557	exoribonuclease II activity
FM037_RS02845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FM037_RS02865	COG0360	Binds together with S18 to 16S ribosomal RNA
FM037_RS02870	COG2965	DNA replication, synthesis of RNA primer
FM037_RS02875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FM037_RS02880	COG0359	binds to the 23S rRNA
FM037_RS02895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FM037_RS03065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FM037_RS03070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FM037_RS03080	COG2356	endonuclease I
FM037_RS03090	COG4227	nucleotidyltransferase activity
FM037_RS03120	COG2205	protein histidine kinase activity
FM037_RS03125	COG0326	Molecular chaperone. Has ATPase activity
FM037_RS03320	COG3550	peptidyl-serine autophosphorylation
FM037_RS03370	COG3177	Filamentation induced by cAMP protein fic
FM037_RS03430	COG1401	restriction endodeoxyribonuclease activity
FM037_RS03485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FM037_RS03505	COG1024	Enoyl-CoA hydratase
FM037_RS03525	COG1538	Outer membrane efflux protein
FM037_RS03530	COG0494	nUDIX hydrolase
FM037_RS03540	COG3151	Protein conserved in bacteria
FM037_RS03550	COG3150	esterase
FM037_RS03575	COG0840	transmembrane signaling receptor activity
FM037_RS03590	COG0584	glycerophosphoryl diester phosphodiesterase
FM037_RS03595	COG3264	Mechanosensitive ion channel
FM037_RS03595	COG1511	domain protein
FM037_RS03610	COG1162	GTPase activity
FM037_RS03615	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FM037_RS03645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FM037_RS03645	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FM037_RS03650	COG0802	atpase or kinase
FM037_RS03660	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FM037_RS03665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FM037_RS03670	COG1923	regulation of RNA biosynthetic process
FM037_RS03675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FM037_RS03680	COG0330	HflC and HflK could
FM037_RS03685	COG0330	HflC and HflK could
FM037_RS03690	COG0723	plastoquinol--plastocyanin reductase activity
FM037_RS03695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FM037_RS03700	COG2857	Cytochrome c1
FM037_RS03705	COG0625	glutathione transferase activity
FM037_RS03710	COG2969	positive regulation of protein catabolic process
FM037_RS03730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FM037_RS03785	COG0429	hydrolase of the alpha beta-hydrolase fold
FM037_RS03795	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FM037_RS03805	COG0488	(ABC) transporter
FM037_RS03810	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FM037_RS03855	COG2813	Specifically methylates the guanine in position
FM037_RS03875	COG1785	Belongs to the alkaline phosphatase family
FM037_RS03880	COG0189	ligase activity
FM037_RS03885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FM037_RS03895	COG3091	SprT-like family
FM037_RS03905	COG0583	DNA-binding transcription factor activity
FM037_RS03910	COG0439	Biotin carboxylase
FM037_RS03915	COG4067	protein conserved in archaea
FM037_RS03915	COG0189	ligase activity
FM037_RS03930	COG3300	MHYT domain
FM037_RS03930	COG5001	Diguanylate cyclase
FM037_RS03940	COG1357	PFAM Pentapeptide repeats (8 copies)
FM037_RS04010	COG0243	molybdopterin cofactor binding
FM037_RS04015	COG3062	negative regulation of establishment of protein localization
FM037_RS04025	COG0577	efflux transmembrane transporter activity
FM037_RS04030	COG1136	(ABC) transporter
FM037_RS04035	COG0730	response to heat
FM037_RS04060	COG0354	folic acid binding
FM037_RS04065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FM037_RS04070	COG3647	Membrane
FM037_RS04085	COG2050	protein possibly involved in aromatic compounds catabolism
FM037_RS04100	COG2119	membrane
FM037_RS04105	COG0814	amino acid
FM037_RS04110	COG4990	cell redox homeostasis
FM037_RS04110	COG3591	Belongs to the peptidase S1B family
FM037_RS04135	COG1187	pseudouridine synthase activity
FM037_RS04145	COG1757	Na H antiporter
FM037_RS04170	COG1280	lysine exporter protein (LysE YggA)
FM037_RS04185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FM037_RS04200	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FM037_RS04205	COG3263	regulation of cellular component size
FM037_RS04240	COG0840	transmembrane signaling receptor activity
FM037_RS04245	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FM037_RS04250	COG0612	Peptidase, M16
FM037_RS04265	COG1560	Kdo2-lipid A biosynthetic process
FM037_RS04290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FM037_RS04295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FM037_RS04300	COG0175	sulfate reduction
FM037_RS04340	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FM037_RS04365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FM037_RS04365	COG1648	precorrin-2 dehydrogenase activity
FM037_RS04385	COG3487	Iron-regulated protein
FM037_RS04410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FM037_RS04420	COG3706	GGDEF domain
FM037_RS04420	COG4251	negative regulation of phosphorylation
FM037_RS04420	COG5001	Diguanylate cyclase
FM037_RS04420	COG2203	Gaf domain
FM037_RS04460	COG1566	PFAM secretion protein HlyD family protein
FM037_RS04470	COG0628	permease
FM037_RS04495	COG0697	spore germination
FM037_RS04530	COG5002	protein histidine kinase activity
FM037_RS04530	COG2205	protein histidine kinase activity
FM037_RS04530	COG0784	Response regulator, receiver
FM037_RS04565	COG1129	ABC transporter
FM037_RS04570	COG1172	Belongs to the binding-protein-dependent transport system permease family
FM037_RS04575	COG1879	ABC-type sugar transport system periplasmic component
FM037_RS04580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FM037_RS04585	COG1609	Transcriptional regulator
FM037_RS04625	COG0583	DNA-binding transcription factor activity
FM037_RS04635	COG1294	oxidase, subunit
FM037_RS04655	COG3220	belongs to the UPF0276 family
FM037_RS04695	COG4191	Histidine kinase
FM037_RS04695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM037_RS04700	COG2314	TM2 domain
FM037_RS04705	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FM037_RS04770	COG0785	Cytochrome C biogenesis protein
FM037_RS04775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FM037_RS04790	COG2423	ornithine cyclodeaminase activity
FM037_RS04795	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FM037_RS04825	COG2814	Major facilitator Superfamily
FM037_RS04830	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS04835	COG0583	DNA-binding transcription factor activity
FM037_RS04870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM037_RS04870	COG4191	Histidine kinase
FM037_RS04880	COG1120	ATPase activity
FM037_RS04885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM037_RS04895	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FM037_RS04905	COG1492	cobalamin metabolic process
FM037_RS04920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FM037_RS04930	COG3038	cytochrome b561
FM037_RS04935	COG3397	chitin binding
FM037_RS04955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS04970	COG1136	(ABC) transporter
FM037_RS04975	COG1136	(ABC) transporter
FM037_RS04975	COG0577	efflux transmembrane transporter activity
FM037_RS04980	COG1136	(ABC) transporter
FM037_RS04980	COG0577	efflux transmembrane transporter activity
FM037_RS04990	COG3852	Histidine kinase
FM037_RS05010	COG1309	transcriptional regulator
FM037_RS05035	COG1902	pentaerythritol trinitrate reductase activity
FM037_RS05040	COG3621	Patatin-like phospholipase
FM037_RS05140	COG1017	nitric oxide dioxygenase activity
FM037_RS05140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FM037_RS05155	COG3604	Transcriptional regulator
FM037_RS05180	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FM037_RS05190	COG2985	domain, Protein
FM037_RS05205	COG2358	TRAP transporter, solute receptor (TAXI family
FM037_RS05230	COG0436	Aminotransferase
FM037_RS05235	COG2166	iron-sulfur cluster assembly
FM037_RS05250	COG0667	Aldo Keto reductase
FM037_RS05260	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FM037_RS05265	COG0814	amino acid
FM037_RS05270	COG1760	l-serine dehydratase
FM037_RS05320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FM037_RS05325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FM037_RS05340	COG0191	fructose-bisphosphate aldolase activity
FM037_RS05385	COG0513	Belongs to the DEAD box helicase family
FM037_RS05390	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FM037_RS05400	COG4974	Belongs to the 'phage' integrase family
FM037_RS05405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FM037_RS05410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FM037_RS05415	COG2264	protein methyltransferase activity
FM037_RS05435	COG0653	protein targeting
FM037_RS05455	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FM037_RS05460	COG2354	Protein conserved in bacteria
FM037_RS05465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FM037_RS05470	COG0583	DNA-binding transcription factor activity
FM037_RS05520	COG0242	peptide deformylase activity
FM037_RS05525	COG2900	Belongs to the SlyX family
FM037_RS05535	COG0545	Peptidyl-prolyl cis-trans isomerase
FM037_RS05540	COG3112	Uncharacterised protein family (UPF0231)
FM037_RS05545	COG2197	response regulator
FM037_RS05550	COG3850	Histidine kinase
FM037_RS05555	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FM037_RS05575	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FM037_RS05590	COG0513	Belongs to the DEAD box helicase family
FM037_RS05600	COG3135	benzoate transporter
FM037_RS05605	COG1396	sequence-specific DNA binding
FM037_RS05620	COG2814	Major facilitator Superfamily
FM037_RS05625	COG1940	carbohydrate kinase activity
FM037_RS05625	COG1846	Transcriptional regulator
FM037_RS05635	COG0006	proline dipeptidase activity
FM037_RS05650	COG0545	Peptidyl-prolyl cis-trans isomerase
FM037_RS05720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FM037_RS05730	COG1301	dicarboxylic acid transport
FM037_RS05745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FM037_RS05750	COG1917	Cupin 2, conserved barrel domain protein
FM037_RS05755	COG0519	Catalyzes the synthesis of GMP from XMP
FM037_RS05755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FM037_RS05780	COG1176	ABC-type spermidine putrescine transport system, permease component I
FM037_RS05785	COG1177	transmembrane transport
FM037_RS05800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FM037_RS05805	COG0358	DNA primase activity
FM037_RS05810	COG1610	YqeY-like protein
FM037_RS05815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FM037_RS05820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FM037_RS05840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FM037_RS05845	COG0069	glutamate synthase activity
FM037_RS05890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FM037_RS05910	COG2124	cytochrome p450
FM037_RS05915	COG2197	response regulator
FM037_RS05920	COG1278	Cold shock
FM037_RS05925	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FM037_RS05935	COG3360	Dodecin
FM037_RS05940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FM037_RS05950	COG0840	transmembrane signaling receptor activity
FM037_RS05955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FM037_RS05965	COG3706	GGDEF domain
FM037_RS05985	COG1228	amidohydrolase
FM037_RS06010	COG0281	malic enzyme
FM037_RS06030	COG2204	response regulator
FM037_RS06055	COG3290	protein histidine kinase activity
FM037_RS06060	COG4565	transcriptional regulatory protein
FM037_RS06065	COG4206	TonB-dependent receptor
FM037_RS06070	COG0625	glutathione transferase activity
FM037_RS06090	COG3590	peptidase
FM037_RS06095	COG1187	pseudouridine synthase activity
FM037_RS06115	COG2423	ornithine cyclodeaminase activity
FM037_RS06130	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FM037_RS06135	COG0564	pseudouridine synthase activity
FM037_RS06145	COG0542	response to heat
FM037_RS06160	COG1183	phosphatidylcholine synthase activity
FM037_RS06190	COG0783	Belongs to the Dps family
FM037_RS06205	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FM037_RS06210	COG0321	lipoyl(octanoyl) transferase activity
FM037_RS06215	COG2921	Belongs to the UPF0250 family
FM037_RS06220	COG1686	Belongs to the peptidase S11 family
FM037_RS06225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FM037_RS06230	COG2951	lytic endotransglycosylase activity
FM037_RS06235	COG0772	Belongs to the SEDS family
FM037_RS06240	COG0768	penicillin binding
FM037_RS06245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FM037_RS06250	COG0799	negative regulation of ribosome biogenesis
FM037_RS06265	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FM037_RS06270	COG0495	leucyl-tRNA aminoacylation
FM037_RS06285	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FM037_RS06295	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FM037_RS06300	COG1702	phosphate starvation-inducible protein PhoH
FM037_RS06305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FM037_RS06315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FM037_RS06320	COG0193	aminoacyl-tRNA hydrolase activity
FM037_RS06325	COG0012	GTP binding
FM037_RS06385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FM037_RS06390	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FM037_RS06395	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FM037_RS06400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FM037_RS06410	COG2890	protein-(glutamine-N5) methyltransferase activity
FM037_RS06425	COG3094	Invasion gene expression up-regulator, SirB
FM037_RS06440	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FM037_RS06445	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FM037_RS06465	COG0733	neurotransmitter:sodium symporter activity
FM037_RS06470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FM037_RS06480	COG1666	GTP binding
FM037_RS06485	COG2211	Major facilitator Superfamily
FM037_RS06530	COG2813	Specifically methylates the guanine in position
FM037_RS06540	COG0271	Belongs to the BolA IbaG family
FM037_RS06560	COG1854	S-ribosylhomocysteine lyase activity
FM037_RS06565	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FM037_RS06570	COG1805	sodium ion transport
FM037_RS06575	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FM037_RS06580	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FM037_RS06585	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FM037_RS06590	COG2871	sodium ion transport
FM037_RS06595	COG1477	protein flavinylation
FM037_RS06600	COG2991	Protein conserved in bacteria
FM037_RS06610	COG2193	ferroxidase activity
FM037_RS06625	COG0583	DNA-binding transcription factor activity
FM037_RS06635	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FM037_RS06650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FM037_RS06655	COG2195	Cleaves the N-terminal amino acid of tripeptides
FM037_RS06660	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FM037_RS06675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FM037_RS06680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FM037_RS06715	COG0443	Heat shock 70 kDa protein
FM037_RS06720	COG0484	heat shock protein binding
FM037_RS06730	COG0545	Peptidyl-prolyl cis-trans isomerase
FM037_RS06735	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FM037_RS06740	COG0505	Belongs to the CarA family
FM037_RS06745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FM037_RS06750	COG0840	transmembrane signaling receptor activity
FM037_RS06775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FM037_RS06780	COG1534	Rna-binding protein
FM037_RS06785	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FM037_RS06795	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FM037_RS06800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FM037_RS06805	COG0149	triose-phosphate isomerase activity
FM037_RS06810	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FM037_RS06825	COG0779	Required for maturation of 30S ribosomal subunits
FM037_RS06830	COG0195	Participates in both transcription termination and antitermination
FM037_RS06835	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FM037_RS06840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FM037_RS06845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FM037_RS06850	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FM037_RS06855	COG3300	MHYT domain
FM037_RS06855	COG5001	Diguanylate cyclase
FM037_RS06860	COG1185	polyribonucleotide nucleotidyltransferase activity
FM037_RS06870	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FM037_RS06880	COG0084	hydrolase, TatD family'
FM037_RS06885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FM037_RS06895	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FM037_RS06900	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FM037_RS06905	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FM037_RS06910	COG0813	purine-nucleoside phosphorylase activity
FM037_RS06920	COG0560	Phosphoserine phosphatase
FM037_RS06935	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FM037_RS06945	COG1335	isochorismatase
FM037_RS06975	COG0745	RESPONSE REGULATOR receiver
FM037_RS06985	COG2205	protein histidine kinase activity
FM037_RS06985	COG2198	Histidine kinase
FM037_RS06985	COG0784	Response regulator, receiver
FM037_RS06990	COG0513	Belongs to the DEAD box helicase family
FM037_RS06995	COG0167	dihydroorotate dehydrogenase activity
FM037_RS07000	COG3381	protein complex oligomerization
FM037_RS07010	COG3005	denitrification pathway
FM037_RS07020	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FM037_RS07025	COG2252	PERMEase
FM037_RS07030	COG0517	IMP dehydrogenase activity
FM037_RS07030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FM037_RS07035	COG2205	protein histidine kinase activity
FM037_RS07035	COG0745	RESPONSE REGULATOR receiver
FM037_RS07035	COG3292	Two component regulator propeller
FM037_RS07040	COG3314	Sporulation integral membrane protein YlbJ
FM037_RS07050	COG0840	transmembrane signaling receptor activity
FM037_RS07060	COG0826	peptidase U32
FM037_RS07065	COG0826	peptidase U32
FM037_RS07070	COG3154	lipid carrier protein
FM037_RS07085	COG2608	mercury ion transmembrane transporter activity
FM037_RS07110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FM037_RS07115	COG0826	peptidase U32
FM037_RS07145	COG0513	Belongs to the DEAD box helicase family
FM037_RS07170	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FM037_RS07180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FM037_RS07190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FM037_RS07195	COG3713	MltA-interacting MipA family protein
FM037_RS07215	COG0745	RESPONSE REGULATOR receiver
FM037_RS07230	COG2205	protein histidine kinase activity
FM037_RS07235	COG0745	RESPONSE REGULATOR receiver
FM037_RS07250	COG2814	Major facilitator Superfamily
FM037_RS07270	COG0813	purine-nucleoside phosphorylase activity
FM037_RS07275	COG4774	siderophore transport
FM037_RS07290	COG1187	pseudouridine synthase activity
FM037_RS07295	COG3064	Membrane
FM037_RS07300	COG2315	Protein conserved in bacteria
FM037_RS07385	COG3344	reverse transcriptase
FM037_RS07395	COG0488	(ABC) transporter
FM037_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FM037_RS07430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FM037_RS07435	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FM037_RS07440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM037_RS07440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM037_RS07455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FM037_RS07460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FM037_RS07465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FM037_RS07470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FM037_RS07480	COG0497	DNA recombination
FM037_RS07505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FM037_RS07510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FM037_RS07515	COG3956	TIGRFAM MazG family protein
FM037_RS07520	COG0504	CTP synthase activity
FM037_RS07525	COG0148	phosphopyruvate hydratase activity
FM037_RS07530	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FM037_RS07535	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FM037_RS07540	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FM037_RS07545	COG0585	pseudouridine synthase activity
FM037_RS07550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FM037_RS07555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FM037_RS07560	COG4942	peptidase
FM037_RS07560	COG1388	LysM domain
FM037_RS07570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FM037_RS07575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FM037_RS07580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FM037_RS07585	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FM037_RS07635	COG3630	sodium ion export across plasma membrane
FM037_RS07640	COG5016	pyruvate
FM037_RS07640	COG0511	ligase activity, forming carbon-carbon bonds
FM037_RS07645	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FM037_RS07655	COG5002	protein histidine kinase activity
FM037_RS07655	COG2205	protein histidine kinase activity
FM037_RS07655	COG0784	Response regulator, receiver
FM037_RS07675	COG0653	protein targeting
FM037_RS07685	COG1301	dicarboxylic acid transport
FM037_RS07690	COG1238	metal cluster binding
FM037_RS07695	COG0612	Peptidase, M16
FM037_RS07700	COG2918	glutathione biosynthetic process
FM037_RS07715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FM037_RS07750	COG4667	esterase of the alpha-beta hydrolase superfamily
FM037_RS07770	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FM037_RS07775	COG2304	oxidoreductase activity
FM037_RS07795	COG0793	Belongs to the peptidase S41A family
FM037_RS07795	COG4946	Tricorn protease homolog
FM037_RS07855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM037_RS07860	COG1902	pentaerythritol trinitrate reductase activity
FM037_RS07865	COG0583	DNA-binding transcription factor activity
FM037_RS07880	COG2197	response regulator
FM037_RS07885	COG4585	Histidine kinase
FM037_RS07915	COG2824	Alkylphosphonate utilization operon protein PhnA
FM037_RS07945	COG3119	arylsulfatase activity
FM037_RS07960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FM037_RS07960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FM037_RS07985	COG0745	RESPONSE REGULATOR receiver
FM037_RS08035	COG2200	EAL domain
FM037_RS08040	COG3710	Transcriptional regulator
FM037_RS08075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FM037_RS08085	COG1012	belongs to the aldehyde dehydrogenase family
FM037_RS08095	COG0583	DNA-binding transcription factor activity
FM037_RS08140	COG0745	RESPONSE REGULATOR receiver
FM037_RS08160	COG0583	DNA-binding transcription factor activity
FM037_RS08215	COG0583	DNA-binding transcription factor activity
FM037_RS08260	COG2186	Transcriptional regulator
FM037_RS08280	COG2197	response regulator
FM037_RS08310	COG2957	Belongs to the agmatine deiminase family
FM037_RS08335	COG2198	Histidine kinase
FM037_RS08335	COG0784	Response regulator, receiver
FM037_RS08335	COG5002	protein histidine kinase activity
FM037_RS08340	COG3710	Transcriptional regulator
FM037_RS08350	COG1671	Belongs to the UPF0178 family
FM037_RS08360	COG1301	dicarboxylic acid transport
FM037_RS08380	COG0786	glutamate:sodium symporter activity
FM037_RS08415	COG1162	GTPase activity
FM037_RS08425	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS08455	COG1960	acyl-CoA dehydrogenase activity
FM037_RS08525	COG1764	response to oxidative stress
FM037_RS08540	COG3829	transcription factor binding
FM037_RS08545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FM037_RS08550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FM037_RS08555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FM037_RS08565	COG0549	Belongs to the carbamate kinase family
FM037_RS08570	COG0493	'glutamate synthase
FM037_RS08575	COG1013	pyruvate-flavodoxin oxidoreductase activity
FM037_RS08575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FM037_RS08575	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FM037_RS08575	COG0674	pyruvate-flavodoxin oxidoreductase activity
FM037_RS08580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FM037_RS08580	COG3608	succinylglutamate desuccinylase aspartoacylase
FM037_RS08585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FM037_RS08590	COG2068	MobA-Related Protein
FM037_RS08595	COG0493	'glutamate synthase
FM037_RS08595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FM037_RS08600	COG0402	S-adenosylhomocysteine deaminase activity
FM037_RS08615	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FM037_RS08620	COG0540	Belongs to the ATCase OTCase family
FM037_RS08625	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FM037_RS08630	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FM037_RS08635	COG2080	2 iron, 2 sulfur cluster binding
FM037_RS08635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FM037_RS08645	COG0402	S-adenosylhomocysteine deaminase activity
FM037_RS08650	COG2252	PERMEase
FM037_RS08680	COG2010	Cytochrome c
FM037_RS08730	COG0688	phosphatidylethanolamine metabolic process
FM037_RS08745	COG3550	peptidyl-serine autophosphorylation
FM037_RS08765	COG0154	amidase activity
FM037_RS08810	COG2030	dehydratase
FM037_RS08810	COG1012	belongs to the aldehyde dehydrogenase family
FM037_RS08820	COG1024	Enoyl-CoA hydratase
FM037_RS08825	COG2050	protein possibly involved in aromatic compounds catabolism
FM037_RS08830	COG0183	Belongs to the thiolase family
FM037_RS08835	COG3396	Phenylacetate-CoA oxygenase
FM037_RS08840	COG3460	Phenylacetate-CoA oxygenase
FM037_RS08845	COG3396	Phenylacetate-CoA oxygenase
FM037_RS08850	COG2151	metal-sulfur cluster biosynthetic enzyme
FM037_RS08855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FM037_RS08860	COG3327	negative regulation of DNA-templated transcription, initiation
FM037_RS08905	COG0318	PFAM AMP-dependent synthetase and ligase
FM037_RS08930	COG2165	general secretion pathway protein
FM037_RS08970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FM037_RS08975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FM037_RS09180	COG3710	Transcriptional regulator
FM037_RS09200	COG1620	l-lactate permease
FM037_RS09205	COG0583	DNA-binding transcription factor activity
FM037_RS09225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FM037_RS09230	COG2867	negative regulation of translational initiation
FM037_RS09235	COG2914	Belongs to the UPF0125 (RnfH) family
FM037_RS09240	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FM037_RS09260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FM037_RS09280	COG3228	Belongs to the MtfA family
FM037_RS09295	COG3530	Putative quorum-sensing-regulated virulence factor
FM037_RS09315	COG1253	flavin adenine dinucleotide binding
FM037_RS09320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FM037_RS09335	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FM037_RS09340	COG0124	histidyl-tRNA synthetase
FM037_RS09345	COG2976	Protein conserved in bacteria
FM037_RS09355	COG1160	GTP binding
FM037_RS09365	COG1570	exodeoxyribonuclease VII activity
FM037_RS09370	COG0516	GMP reductase activity
FM037_RS09370	COG0517	IMP dehydrogenase activity
FM037_RS09375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FM037_RS09375	COG0519	Catalyzes the synthesis of GMP from XMP
FM037_RS09385	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FM037_RS09400	COG1294	oxidase, subunit
FM037_RS09405	COG4890	Cyd operon protein YbgT
FM037_RS09410	COG0840	transmembrane signaling receptor activity
FM037_RS09410	COG3290	protein histidine kinase activity
FM037_RS09425	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FM037_RS09430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FM037_RS09475	COG1086	Polysaccharide biosynthesis protein
FM037_RS09480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FM037_RS09485	COG1083	cytidylyl-transferase
FM037_RS09495	COG2089	acid synthase
FM037_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS09515	COG0318	PFAM AMP-dependent synthetase and ligase
FM037_RS09540	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FM037_RS09550	COG1215	transferase activity, transferring glycosyl groups
FM037_RS09555	COG0673	inositol 2-dehydrogenase activity
FM037_RS09625	COG0784	Response regulator, receiver
FM037_RS09625	COG0835	chemotaxis
FM037_RS09630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FM037_RS09635	COG1815	bacterial-type flagellum-dependent cell motility
FM037_RS09645	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FM037_RS09655	COG1749	Flagellar hook protein flgE
FM037_RS09660	COG4787	bacterial-type flagellum-dependent cell motility
FM037_RS09675	COG1706	bacterial-type flagellum-dependent cell motility
FM037_RS09680	COG3951	Flagellar rod assembly protein muramidase FlgJ
FM037_RS09680	COG1705	Flagellar rod assembly protein muramidase FlgJ
FM037_RS09685	COG1256	bacterial-type flagellum assembly
FM037_RS09685	COG4786	Flagellar basal body rod
FM037_RS09690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FM037_RS09705	COG1334	flagellar protein FlaG
FM037_RS09710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FM037_RS09720	COG1516	flagellar protein fliS
FM037_RS09740	COG1677	Flagellar hook-basal body complex protein FliE
FM037_RS09750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FM037_RS09800	COG1987	bacterial-type flagellum assembly
FM037_RS09840	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FM037_RS09845	COG2198	Histidine kinase
FM037_RS09845	COG0784	Response regulator, receiver
FM037_RS09845	COG0643	Histidine kinase
FM037_RS09860	COG1192	Involved in chromosome partitioning
FM037_RS09870	COG0835	chemotaxis
FM037_RS09895	COG0745	RESPONSE REGULATOR receiver
FM037_RS09905	COG3104	oligopeptide transport
FM037_RS09910	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FM037_RS09935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FM037_RS09940	COG1051	belongs to the nudix hydrolase family
FM037_RS09945	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FM037_RS09945	COG0662	Cupin 2, conserved barrel domain protein
FM037_RS09995	COG1215	transferase activity, transferring glycosyl groups
FM037_RS10010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FM037_RS10020	COG1696	Membrane protein involved in D-alanine export
FM037_RS10055	COG1331	Highly conserved protein containing a thioredoxin domain
FM037_RS10060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FM037_RS10065	COG0175	sulfate reduction
FM037_RS10070	COG2895	sulfate adenylyltransferase (ATP) activity
FM037_RS10075	COG3273	potassium ion transport
FM037_RS10075	COG0471	metal ion transport
FM037_RS10080	COG0529	Catalyzes the synthesis of activated sulfate
FM037_RS10095	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FM037_RS10110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FM037_RS10125	COG1366	Belongs to the anti-sigma-factor antagonist family
FM037_RS10150	COG2204	response regulator
FM037_RS10155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FM037_RS10170	COG1940	carbohydrate kinase activity
FM037_RS10190	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FM037_RS10190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FM037_RS10195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FM037_RS10225	COG0625	glutathione transferase activity
FM037_RS10235	COG0583	DNA-binding transcription factor activity
FM037_RS10255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FM037_RS10265	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FM037_RS10310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FM037_RS10370	COG1132	(ABC) transporter
FM037_RS10380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FM037_RS10385	COG0513	Belongs to the DEAD box helicase family
FM037_RS10395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FM037_RS10400	COG0784	Response regulator, receiver
FM037_RS10400	COG0835	chemotaxis
FM037_RS10405	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FM037_RS10425	COG0438	transferase activity, transferring glycosyl groups
FM037_RS10485	COG0438	transferase activity, transferring glycosyl groups
FM037_RS10490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FM037_RS10490	COG2755	lipolytic protein G-D-S-L family
FM037_RS10510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FM037_RS10515	COG0343	queuine tRNA-ribosyltransferase activity
FM037_RS10520	COG1862	Preprotein translocase
FM037_RS10525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FM037_RS10530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FM037_RS10545	COG4681	YaeQ
FM037_RS10590	COG1959	2 iron, 2 sulfur cluster binding
FM037_RS10595	COG1104	cysteine desulfurase activity
FM037_RS10600	COG0822	iron-sulfur transferase activity
FM037_RS10610	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FM037_RS10615	COG0443	Heat shock 70 kDa protein
FM037_RS10620	COG0633	Ferredoxin
FM037_RS10625	COG2975	iron-sulfur cluster assembly
FM037_RS10630	COG0105	UTP biosynthetic process
FM037_RS10660	COG5001	Diguanylate cyclase
FM037_RS10660	COG3300	MHYT domain
FM037_RS10675	COG4181	ATPase activity
FM037_RS10690	COG1090	epimerase
FM037_RS10695	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FM037_RS10700	COG0628	permease
FM037_RS10705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FM037_RS10720	COG0280	phosphate acetyltransferase
FM037_RS10720	COG0857	belongs to the CobB CobQ family
FM037_RS10725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FM037_RS10730	COG3092	negative regulation of chromosome organization
FM037_RS10735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FM037_RS10740	COG1882	Formate acetyltransferase
FM037_RS10745	COG2116	formate transmembrane transporter activity
FM037_RS10750	COG1288	antiporter activity
FM037_RS10770	COG1007	ATP synthesis coupled electron transport
FM037_RS10775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM037_RS10785	COG0713	ATP synthesis coupled electron transport
FM037_RS10795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM037_RS10800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FM037_RS10820	COG0649	NAD binding
FM037_RS10825	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM037_RS10830	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM037_RS10835	COG0516	GMP reductase activity
FM037_RS10835	COG0517	IMP dehydrogenase activity
FM037_RS10845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FM037_RS10880	COG1012	belongs to the aldehyde dehydrogenase family
FM037_RS10885	COG1309	transcriptional regulator
FM037_RS10895	COG1944	ATP diphosphatase activity
FM037_RS10910	COG2153	protein acetylation
FM037_RS10915	COG0697	spore germination
FM037_RS10920	COG1522	sequence-specific DNA binding
FM037_RS10930	COG0671	phosphoesterase, PA-phosphatase related
FM037_RS10950	COG4968	Prepilin-type N-terminal cleavage methylation domain
FM037_RS10990	COG1196	nuclear chromosome segregation
FM037_RS10995	COG3115	cell septum assembly
FM037_RS11010	COG0583	DNA-binding transcription factor activity
FM037_RS11015	COG2885	chlorophyll binding
FM037_RS11035	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FM037_RS11040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FM037_RS11055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FM037_RS11060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FM037_RS11070	COG1733	regulation of RNA biosynthetic process
FM037_RS11075	COG1012	belongs to the aldehyde dehydrogenase family
FM037_RS11085	COG0589	response to stress
FM037_RS11130	COG1597	lipid kinase activity
FM037_RS11165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FM037_RS11185	COG0517	IMP dehydrogenase activity
FM037_RS11185	COG0516	GMP reductase activity
FM037_RS11190	COG2176	DNA-directed DNA polymerase activity
FM037_RS11200	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FM037_RS11205	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FM037_RS11215	COG2080	2 iron, 2 sulfur cluster binding
FM037_RS11220	COG2010	Cytochrome c
FM037_RS11220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FM037_RS11240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FM037_RS11250	COG1012	belongs to the aldehyde dehydrogenase family
FM037_RS11255	COG3938	Belongs to the proline racemase family
FM037_RS11265	COG3938	Belongs to the proline racemase family
FM037_RS11270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FM037_RS11305	COG0006	proline dipeptidase activity
FM037_RS11310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FM037_RS11345	COG4667	esterase of the alpha-beta hydrolase superfamily
FM037_RS11390	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FM037_RS11420	COG2204	response regulator
FM037_RS11425	COG2239	Acts as a magnesium transporter
FM037_RS11435	COG1280	lysine exporter protein (LysE YggA)
FM037_RS11445	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FM037_RS11460	COG3706	GGDEF domain
FM037_RS11465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FM037_RS11485	COG3082	Protein of unknown function (DUF1414)
FM037_RS11490	COG3081	Nucleoid-associated protein
FM037_RS11510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FM037_RS11550	COG0840	transmembrane signaling receptor activity
FM037_RS11570	COG2205	protein histidine kinase activity
FM037_RS11570	COG0784	Response regulator, receiver
FM037_RS11590	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FM037_RS11620	COG4774	siderophore transport
FM037_RS11625	COG3102	Protein conserved in bacteria
FM037_RS11635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FM037_RS11665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FM037_RS11665	COG1017	nitric oxide dioxygenase activity
FM037_RS11700	COG0367	asparagine synthase
FM037_RS11705	COG2234	aminopeptidase activity
FM037_RS11710	COG0647	UMP catabolic process
FM037_RS11755	COG0671	phosphoesterase, PA-phosphatase related
FM037_RS11760	COG2610	gluconate transmembrane transporter activity
FM037_RS11765	COG3265	gluconokinase activity
FM037_RS11785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FM037_RS11790	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FM037_RS11795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FM037_RS11800	COG2056	Na+-H+ antiporter family
FM037_RS11805	COG0450	alkyl hydroperoxide reductase
FM037_RS11815	COG2885	chlorophyll binding
FM037_RS11825	COG0824	Thioesterase
FM037_RS11830	COG0811	peptide transport
FM037_RS11845	COG0823	Involved in the tonB-independent uptake of proteins
FM037_RS11850	COG2885	chlorophyll binding
FM037_RS11855	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FM037_RS11910	COG1061	Type III restriction enzyme res subunit
FM037_RS11915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FM037_RS11925	COG0179	Fumarylacetoacetate (FAA) hydrolase
FM037_RS11930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FM037_RS11940	COG1607	acyl-coa hydrolase
FM037_RS11955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FM037_RS11960	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FM037_RS11965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FM037_RS11965	COG0574	Belongs to the PEP-utilizing enzyme family
FM037_RS11970	COG0277	FAD linked oxidase domain protein
FM037_RS11970	COG0247	lactate metabolic process
FM037_RS12005	COG2850	peptidyl-arginine hydroxylation
FM037_RS12010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FM037_RS12015	COG2915	High frequency lysogenization protein hflD homolog
FM037_RS12020	COG0482	sulfurtransferase activity
FM037_RS12030	COG1187	pseudouridine synthase activity
FM037_RS12040	COG1278	Cold shock
FM037_RS12045	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FM037_RS12050	COG0542	response to heat
FM037_RS12055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FM037_RS12060	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FM037_RS12070	COG3134	Outer membrane lipoprotein
FM037_RS12080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FM037_RS12095	COG0626	cystathionine gamma-synthase activity
FM037_RS12100	COG2205	protein histidine kinase activity
FM037_RS12105	COG0745	RESPONSE REGULATOR receiver
FM037_RS12125	COG3706	GGDEF domain
FM037_RS12130	COG3008	intermembrane lipid transfer
FM037_RS12135	COG2995	paraquat-inducible protein a
FM037_RS12140	COG2995	paraquat-inducible protein a
FM037_RS12145	COG3141	response to X-ray
FM037_RS12150	COG1956	GAF domain-containing protein
FM037_RS12155	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FM037_RS12165	COG0308	aminopeptidase N
FM037_RS12185	COG4447	cellulose binding
FM037_RS12200	COG0167	dihydroorotate dehydrogenase activity
FM037_RS12210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FM037_RS12210	COG0116	Belongs to the methyltransferase superfamily
FM037_RS12220	COG0488	(ABC) transporter
FM037_RS12230	COG3130	regulation of translation
FM037_RS12235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FM037_RS12240	COG1067	ATP-dependent peptidase activity
FM037_RS12250	COG2197	response regulator
FM037_RS12255	COG0322	excinuclease ABC activity
FM037_RS12290	COG2989	Protein conserved in bacteria
FM037_RS12295	COG3108	Peptidase M15
FM037_RS12300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FM037_RS12305	COG2719	SpoVR family
FM037_RS12310	COG2718	Belongs to the UPF0229 family
FM037_RS12315	COG2766	serine protein kinase
FM037_RS12325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FM037_RS12355	COG1393	Belongs to the ArsC family
FM037_RS12360	COG4783	chaperone-mediated protein folding
FM037_RS12375	COG0583	DNA-binding transcription factor activity
FM037_RS12385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FM037_RS12390	COG2716	regulation of RNA biosynthetic process
FM037_RS12395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FM037_RS12400	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FM037_RS12410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM037_RS12435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FM037_RS12445	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FM037_RS12450	COG1454	alcohol dehydrogenase
FM037_RS12455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FM037_RS12460	COG0288	reversible hydration of carbon dioxide
FM037_RS12465	COG0596	Alpha beta hydrolase
FM037_RS12480	COG1393	Belongs to the ArsC family
FM037_RS12500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FM037_RS12505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FM037_RS12525	COG2176	DNA-directed DNA polymerase activity
FM037_RS12530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FM037_RS12535	COG2850	peptidyl-arginine hydroxylation
FM037_RS12570	COG0840	transmembrane signaling receptor activity
FM037_RS12585	COG0697	spore germination
FM037_RS12590	COG0346	lactoylglutathione lyase activity
FM037_RS12595	COG1082	Xylose isomerase domain protein TIM barrel
FM037_RS12600	COG2808	Putative FMN-binding domain
FM037_RS12610	COG0393	Putative heavy-metal-binding
FM037_RS12620	COG0454	-acetyltransferase
FM037_RS12625	COG0569	domain protein
FM037_RS12655	COG1760	l-serine dehydratase
FM037_RS12660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FM037_RS12665	COG0509	glycine decarboxylation via glycine cleavage system
FM037_RS12670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FM037_RS12670	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FM037_RS12685	COG1757	Na H antiporter
FM037_RS12690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FM037_RS12720	COG2207	Transcriptional regulator
FM037_RS12725	COG2807	transmembrane transport
FM037_RS12730	COG0513	Belongs to the DEAD box helicase family
FM037_RS12735	COG1523	belongs to the glycosyl hydrolase 13 family
FM037_RS12740	COG0366	Alpha amylase catalytic
FM037_RS12750	COG0366	Alpha amylase catalytic
FM037_RS12760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FM037_RS12760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FM037_RS12775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FM037_RS12780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FM037_RS12805	COG3706	GGDEF domain
FM037_RS12845	COG3706	GGDEF domain
FM037_RS12855	COG0463	Glycosyl transferase, family 2
FM037_RS12880	COG2989	Protein conserved in bacteria
FM037_RS12960	COG0017	Asparaginyl-tRNA synthetase
FM037_RS12975	COG0494	nUDIX hydrolase
FM037_RS12980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FM037_RS12990	COG0823	Involved in the tonB-independent uptake of proteins
FM037_RS12990	COG1506	peptidase
FM037_RS13025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FM037_RS13030	COG1454	alcohol dehydrogenase
FM037_RS13030	COG1012	belongs to the aldehyde dehydrogenase family
FM037_RS13035	COG2095	MarC family integral membrane protein
FM037_RS13055	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FM037_RS13060	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FM037_RS13070	COG0436	Aminotransferase
FM037_RS13075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FM037_RS13085	COG0716	FMN binding
FM037_RS13100	COG0596	Alpha beta hydrolase
FM037_RS13105	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FM037_RS13110	COG0033	Phosphoglucomutase
FM037_RS13115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FM037_RS13120	COG2988	succinylglutamate desuccinylase activity
FM037_RS13130	COG0022	dehydrogenase e1 component
FM037_RS13145	COG0840	transmembrane signaling receptor activity
FM037_RS13175	COG0514	ATP-dependent DNA helicase (RecQ)
FM037_RS13185	COG0745	RESPONSE REGULATOR receiver
FM037_RS13190	COG2866	Carboxypeptidase
FM037_RS13200	COG3139	Protein of unknown function (DUF1315)
FM037_RS13205	COG0252	asparaginase activity
FM037_RS13210	COG0616	signal peptide processing
FM037_RS13215	COG0446	pyridine nucleotide-disulphide oxidoreductase
FM037_RS13215	COG1902	pentaerythritol trinitrate reductase activity
FM037_RS13235	COG1487	ribonuclease activity
FM037_RS13260	COG3501	Rhs element vgr protein
FM037_RS13315	COG2197	response regulator
FM037_RS13325	COG0583	DNA-binding transcription factor activity
FM037_RS13355	COG2207	Transcriptional regulator
FM037_RS13360	COG0840	transmembrane signaling receptor activity
FM037_RS13365	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FM037_RS13380	COG4680	protein conserved in bacteria
FM037_RS13465	COG2003	Belongs to the UPF0758 family
FM037_RS13495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM037_RS13495	COG4191	Histidine kinase
FM037_RS13515	COG3077	Addiction module antitoxin, RelB DinJ family
FM037_RS13580	COG0644	oxidoreductase
FM037_RS13690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FM037_RS13695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FM037_RS13700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FM037_RS13710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FM037_RS13720	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FM037_RS13725	COG1448	Aminotransferase
FM037_RS13730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FM037_RS13735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FM037_RS13740	COG0539	negative regulation of cytoplasmic translation
FM037_RS13745	COG0776	regulation of translation
FM037_RS13755	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FM037_RS13760	COG0284	orotidine-5'-phosphate decarboxylase activity
FM037_RS13770	COG3122	Protein conserved in bacteria
FM037_RS13775	COG1960	acyl-CoA dehydrogenase activity
FM037_RS13780	COG2027	D-alanyl-D-alanine carboxypeptidase
FM037_RS13795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FM037_RS13800	COG2814	Major facilitator Superfamily
FM037_RS13805	COG3148	PFAM DTW domain containing protein
FM037_RS13850	COG2205	protein histidine kinase activity
FM037_RS13850	COG0784	Response regulator, receiver
FM037_RS13870	COG2814	Major facilitator Superfamily
FM037_RS13880	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FM037_RS13935	COG1715	Restriction endonuclease
FM037_RS13970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM037_RS13990	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FM037_RS14000	COG0583	DNA-binding transcription factor activity
FM037_RS14020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FM037_RS14050	COG2165	general secretion pathway protein
FM037_RS14075	COG0488	(ABC) transporter
FM037_RS14080	COG0318	PFAM AMP-dependent synthetase and ligase
FM037_RS14095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM037_RS14100	COG1404	Belongs to the peptidase S8 family
FM037_RS14110	COG0564	pseudouridine synthase activity
FM037_RS14165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FM037_RS14190	COG2193	ferroxidase activity
FM037_RS14200	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FM037_RS14205	COG3706	GGDEF domain
FM037_RS14210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FM037_RS14245	COG1448	Aminotransferase
FM037_RS14255	COG2992	FlgJ-related protein
FM037_RS14265	COG0037	tRNA processing
FM037_RS14270	COG0589	response to stress
FM037_RS14275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FM037_RS14290	COG2217	Heavy metal translocating P-type atpase
FM037_RS14300	COG2010	Cytochrome c
FM037_RS14315	COG3278	Belongs to the heme-copper respiratory oxidase family
FM037_RS14325	COG3437	response regulator, receiver
FM037_RS14325	COG0784	Response regulator, receiver
FM037_RS14340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FM037_RS14345	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS14375	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FM037_RS14380	COG1280	lysine exporter protein (LysE YggA)
FM037_RS14410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM037_RS14410	COG4191	Histidine kinase
FM037_RS14415	COG2072	flavoprotein involved in K transport
FM037_RS14435	COG5001	Diguanylate cyclase
FM037_RS14435	COG2203	Gaf domain
FM037_RS14435	COG4251	negative regulation of phosphorylation
FM037_RS14435	COG3706	GGDEF domain
FM037_RS14440	COG1027	Aspartate ammonia-lyase
FM037_RS14450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FM037_RS14460	COG0583	DNA-binding transcription factor activity
FM037_RS14465	COG3706	GGDEF domain
FM037_RS14490	COG1067	ATP-dependent peptidase activity
FM037_RS14510	COG1227	inorganic diphosphatase activity
FM037_RS14620	COG2207	Transcriptional regulator
FM037_RS14705	COG1404	Belongs to the peptidase S8 family
FM037_RS14715	COG2197	response regulator
FM037_RS14720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FM037_RS14740	COG3209	COG3209 Rhs family protein
FM037_RS14775	COG3501	Rhs element vgr protein
FM037_RS14805	COG3829	transcription factor binding
FM037_RS14865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS14870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM037_RS14885	COG2814	Major facilitator Superfamily
FM037_RS14890	COG0583	DNA-binding transcription factor activity
FM037_RS14895	COG0670	Belongs to the BI1 family
FM037_RS14900	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FM037_RS14905	COG2923	Belongs to the DsrF TusC family
FM037_RS14920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FM037_RS14925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FM037_RS14930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FM037_RS14940	COG0531	amino acid
FM037_RS14940	COG1674	ftsk spoiiie
FM037_RS14950	COG0686	Belongs to the AlaDH PNT family
FM037_RS14955	COG0492	ferredoxin-NADP+ reductase activity
FM037_RS14960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FM037_RS14970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FM037_RS14975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FM037_RS14980	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS14990	COG0307	riboflavin synthase, alpha
FM037_RS14995	COG0534	Mate efflux family protein
FM037_RS15065	COG0281	malic enzyme
FM037_RS15075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FM037_RS15080	COG2252	PERMEase
FM037_RS15090	COG1414	Transcriptional regulator
FM037_RS15100	COG3616	Alanine racemase, N-terminal domain
FM037_RS15105	COG2423	ornithine cyclodeaminase activity
FM037_RS15155	COG1960	acyl-CoA dehydrogenase activity
FM037_RS15160	COG0469	pyruvate kinase activity
FM037_RS15165	COG1737	Transcriptional regulator
FM037_RS15170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FM037_RS15175	COG0363	glucosamine-6-phosphate deaminase activity
FM037_RS15180	COG0129	dihydroxy-acid dehydratase activity
FM037_RS15185	COG0800	Aldolase
FM037_RS15210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FM037_RS15230	COG3424	synthase
FM037_RS15240	COG2194	sulfuric ester hydrolase activity
FM037_RS15250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM037_RS15250	COG0045	succinate-CoA ligase (ADP-forming) activity
FM037_RS15250	COG1042	CoA-binding domain protein
FM037_RS15260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FM037_RS15270	COG4266	Belongs to the allantoicase family
FM037_RS15280	COG2351	hydroxyisourate hydrolase activity
FM037_RS15290	COG0402	S-adenosylhomocysteine deaminase activity
FM037_RS15300	COG1309	transcriptional regulator
FM037_RS15305	COG4413	Urea transporter
FM037_RS15335	COG0602	queuosine metabolic process
FM037_RS15340	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FM037_RS15350	COG0556	nucleotide-excision repair
FM037_RS15390	COG4657	Part of a membrane complex involved in electron transport
FM037_RS15395	COG2878	Part of a membrane complex involved in electron transport
FM037_RS15405	COG4658	electron transport chain
FM037_RS15415	COG4660	Part of a membrane complex involved in electron transport
FM037_RS15420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FM037_RS15460	COG2255	four-way junction helicase activity
FM037_RS15465	COG0632	four-way junction helicase activity
FM037_RS15470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FM037_RS15475	COG0217	transcriptional regulatory protein
FM037_RS15480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FM037_RS15490	COG2226	methyltransferase
FM037_RS15500	COG0189	ligase activity
FM037_RS15500	COG4067	protein conserved in archaea
FM037_RS15540	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FM037_RS15545	COG2022	thiamine diphosphate biosynthetic process
FM037_RS15555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FM037_RS15575	COG1272	protein, Hemolysin III
FM037_RS15590	COG0242	peptide deformylase activity
FM037_RS15610	COG0121	glutamine amidotransferase
FM037_RS15615	COG1960	acyl-CoA dehydrogenase activity
FM037_RS15645	COG0328	RNA-DNA hybrid ribonuclease activity
FM037_RS15650	COG0583	DNA-binding transcription factor activity
FM037_RS15655	COG2226	methyltransferase
FM037_RS15665	COG0741	lytic transglycosylase activity
FM037_RS15665	COG1388	LysM domain
FM037_RS15680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FM037_RS15700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FM037_RS15705	COG1322	Protein conserved in bacteria
FM037_RS15710	COG0741	lytic transglycosylase activity
FM037_RS15720	COG0714	Associated with various cellular activities
FM037_RS15755	COG2132	Multicopper oxidase
FM037_RS15770	COG0739	heme binding
FM037_RS15780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FM037_RS15785	COG1074	ATP-dependent DNA helicase activity
FM037_RS15790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FM037_RS15810	COG1247	-acetyltransferase
FM037_RS15830	COG1181	Belongs to the D-alanine--D-alanine ligase family
FM037_RS15875	COG1643	Atp-dependent helicase
FM037_RS15880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FM037_RS15885	COG0402	S-adenosylhomocysteine deaminase activity
FM037_RS15910	COG3436	PFAM IS66 Orf2 family protein
FM037_RS15930	COG3344	reverse transcriptase
FM037_RS15945	COG0113	porphobilinogen synthase activity
FM037_RS15975	COG0583	DNA-binding transcription factor activity
FM037_RS15980	COG0517	IMP dehydrogenase activity
FM037_RS15980	COG1125	glycine betaine transport
FM037_RS15985	COG1280	lysine exporter protein (LysE YggA)
FM037_RS16005	COG2911	Protein conserved in bacteria
FM037_RS16015	COG2186	Transcriptional regulator
FM037_RS16020	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FM037_RS16025	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FM037_RS16030	COG2983	Belongs to the UPF0260 family
FM037_RS16040	COG3100	YcgL domain-containing protein
FM037_RS16045	COG0850	regulation of cytokinetic process
FM037_RS16050	COG2894	cell division
FM037_RS16055	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FM037_RS16060	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FM037_RS16065	COG0318	PFAM AMP-dependent synthetase and ligase
FM037_RS16090	COG1214	PFAM Peptidase M22, glycoprotease
FM037_RS16095	COG0519	Catalyzes the synthesis of GMP from XMP
FM037_RS16105	COG1012	belongs to the aldehyde dehydrogenase family
FM037_RS16110	COG0174	glutamine synthetase
FM037_RS16120	COG0583	DNA-binding transcription factor activity
FM037_RS16125	COG1252	NADH dehydrogenase
FM037_RS16140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FM037_RS16155	COG1199	ATP-dependent helicase activity
FM037_RS16165	COG2964	Protein conserved in bacteria
FM037_RS16170	COG3681	Belongs to the UPF0597 family
FM037_RS16195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FM037_RS16200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FM037_RS16210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FM037_RS16215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FM037_RS16220	COG0107	imidazoleglycerol-phosphate synthase activity
FM037_RS16225	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FM037_RS16225	COG0140	phosphoribosyl-ATP diphosphatase activity
FM037_RS16240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FM037_RS16245	COG0589	response to stress
FM037_RS16250	COG0659	secondary active sulfate transmembrane transporter activity
FM037_RS16265	COG0776	regulation of translation
FM037_RS16270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FM037_RS16270	COG0072	phenylalanine-tRNA ligase activity
FM037_RS16275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FM037_RS16320	COG0010	Belongs to the arginase family
FM037_RS16330	COG1166	arginine decarboxylase activity
FM037_RS16340	COG3132	Protein of unknown function, DUF480
FM037_RS16350	COG1131	(ABC) transporter
FM037_RS16355	COG1278	Cold shock
FM037_RS16360	COG2226	methyltransferase
FM037_RS16460	COG3941	tape measure
FM037_RS16490	COG0740	serine-type endopeptidase activity
FM037_RS16525	COG3772	lysozyme
FM037_RS16535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FM037_RS16660	COG2925	Exonuclease
FM037_RS16665	COG0295	cytidine deaminase activity
FM037_RS16670	COG2084	Dehydrogenase
FM037_RS16695	COG3706	GGDEF domain
FM037_RS16720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FM037_RS16725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FM037_RS16730	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS16740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FM037_RS16745	COG0416	fatty acid biosynthetic process
FM037_RS16750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FM037_RS16755	COG1399	metal-binding, possibly nucleic acid-binding protein
FM037_RS16760	COG0424	maF-like protein
FM037_RS16770	COG0546	phosphoglycolate phosphatase activity
FM037_RS16780	COG1530	ribonuclease E activity
FM037_RS16800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FM037_RS16805	COG1793	dna ligase
FM037_RS16810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FM037_RS16820	COG2715	membrane protein required for spore maturation
FM037_RS16825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FM037_RS16825	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FM037_RS16830	COG0084	hydrolase, TatD family'
FM037_RS16845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FM037_RS16850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FM037_RS16855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FM037_RS16860	COG0717	Belongs to the dCTP deaminase family
FM037_RS16865	COG0572	uridine kinase
FM037_RS16875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FM037_RS16875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FM037_RS16880	COG2897	thiosulfate sulfurtransferase activity
FM037_RS16885	COG0456	acetyltransferase
FM037_RS16900	COG0443	Heat shock 70 kDa protein
FM037_RS16910	COG0442	prolyl-tRNA aminoacylation
FM037_RS16915	COG1030	water channel activity
FM037_RS16925	COG1054	Belongs to the UPF0176 family
FM037_RS16935	COG0456	acetyltransferase
FM037_RS16945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM037_RS16950	COG2814	Major facilitator Superfamily
FM037_RS16955	COG0028	Belongs to the TPP enzyme family
FM037_RS16960	COG0440	acetolactate synthase activity
FM037_RS16975	COG0737	Belongs to the 5'-nucleotidase family
FM037_RS16980	COG0400	carboxylic ester hydrolase activity
FM037_RS16985	COG0435	Glutathione S-transferase
FM037_RS17005	COG2951	lytic endotransglycosylase activity
FM037_RS17020	COG0835	chemotaxis
FM037_RS17020	COG0784	Response regulator, receiver
FM037_RS17025	COG0668	transmembrane transport
FM037_RS17055	COG1858	cytochrome C peroxidase
FM037_RS17075	COG1280	lysine exporter protein (LysE YggA)
FM037_RS17085	COG0405	Gamma-glutamyltransferase
FM037_RS17090	COG0339	signal peptide processing
FM037_RS17100	COG0737	Belongs to the 5'-nucleotidase family
FM037_RS17110	COG0384	phenazine biosynthesis protein PhzF
FM037_RS17125	COG3033	Beta-eliminating lyase
FM037_RS17140	COG2205	protein histidine kinase activity
FM037_RS17145	COG0745	RESPONSE REGULATOR receiver
FM037_RS17160	COG0583	DNA-binding transcription factor activity
FM037_RS17180	COG0840	transmembrane signaling receptor activity
FM037_RS17190	COG1881	PFAM PEBP family protein
FM037_RS17195	COG1960	acyl-CoA dehydrogenase activity
FM037_RS17215	COG3784	Protein of unknown function (DUF1318)
FM037_RS17225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FM037_RS17310	COG1794	racemase activity, acting on amino acids and derivatives
FM037_RS17380	COG1429	ligase activity, forming nitrogen-metal bonds
FM037_RS17390	COG1136	(ABC) transporter
FM037_RS17390	COG0577	efflux transmembrane transporter activity
FM037_RS17440	COG0745	RESPONSE REGULATOR receiver
FM037_RS17485	COG0778	Nitroreductase
FM037_RS17510	COG4773	Receptor
FM037_RS17525	COG0537	adenosine 5'-monophosphoramidase activity
FM037_RS17530	COG1309	transcriptional regulator
FM037_RS17555	COG2197	response regulator
FM037_RS17585	COG0515	serine threonine protein kinase
FM037_RS17585	COG2815	serine threonine protein kinase
FM037_RS17590	COG2223	nitrite transmembrane transporter activity
FM037_RS17595	COG2146	nitrite reductase [NAD(P)H] activity
FM037_RS17600	COG2146	nitrite reductase [NAD(P)H] activity
FM037_RS17600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FM037_RS17610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FM037_RS17615	COG1648	precorrin-2 dehydrogenase activity
FM037_RS17615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FM037_RS17625	COG1053	succinate dehydrogenase
FM037_RS17630	COG0501	Belongs to the peptidase M48B family
FM037_RS17635	COG0339	signal peptide processing
FM037_RS17645	COG2226	methyltransferase
FM037_RS17655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FM037_RS17660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FM037_RS17660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FM037_RS17680	COG0583	DNA-binding transcription factor activity
FM037_RS17690	COG4948	Mandelate Racemase Muconate Lactonizing
FM037_RS17700	COG0437	4 iron, 4 sulfur cluster binding
FM037_RS17705	COG0243	molybdopterin cofactor binding
FM037_RS17710	COG4574	serine-type endopeptidase inhibitor activity
FM037_RS17745	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FM037_RS17750	COG0735	belongs to the Fur family
FM037_RS17760	COG0069	glutamate synthase activity
FM037_RS17770	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FM037_RS17775	COG0045	succinate-CoA ligase (ADP-forming) activity
FM037_RS17780	COG0508	dehydrogenase complex catalyzes the overall conversion of
FM037_RS17785	COG0567	Dehydrogenase, E1 component
FM037_RS17790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FM037_RS17795	COG1053	succinate dehydrogenase
FM037_RS17800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FM037_RS17830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS17855	COG0515	serine threonine protein kinase
FM037_RS17860	COG2835	tetraacyldisaccharide 4'-kinase activity
FM037_RS17865	COG1663	tetraacyldisaccharide 4'-kinase activity
FM037_RS17870	COG1132	(ABC) transporter
FM037_RS17885	COG4591	ABC-type transport system involved in lipoprotein release permease component
FM037_RS17890	COG1136	(ABC) transporter
FM037_RS17895	COG4591	ABC-type transport system involved in lipoprotein release permease component
FM037_RS17905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FM037_RS17915	COG1254	Belongs to the acylphosphatase family
FM037_RS17920	COG3150	esterase
FM037_RS17925	COG1472	Belongs to the glycosyl hydrolase 3 family
FM037_RS17930	COG1760	l-serine dehydratase
FM037_RS17950	COG3724	N-succinylarginine dihydrolase activity
FM037_RS17960	COG1301	dicarboxylic acid transport
FM037_RS17965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FM037_RS17970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FM037_RS17975	COG0563	adenylate kinase activity
FM037_RS17980	COG3118	belongs to the thioredoxin family
FM037_RS17985	COG0326	Molecular chaperone. Has ATPase activity
FM037_RS17990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FM037_RS17995	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FM037_RS18005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FM037_RS18010	COG2832	Protein of unknown function (DUF454)
FM037_RS18020	COG3220	belongs to the UPF0276 family
FM037_RS18040	COG0616	signal peptide processing
FM037_RS18045	COG2267	carboxylic ester hydrolase activity
FM037_RS18050	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS18060	COG1187	pseudouridine synthase activity
FM037_RS18065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FM037_RS18075	COG0009	L-threonylcarbamoyladenylate synthase
FM037_RS18080	COG0613	PHP domain protein
FM037_RS18085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FM037_RS18090	COG0512	Glutamine amidotransferase of anthranilate synthase
FM037_RS18095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FM037_RS18100	COG0134	indole-3-glycerol-phosphate synthase activity
FM037_RS18100	COG0135	phosphoribosylanthranilate isomerase activity
FM037_RS18105	COG0133	tryptophan synthase activity
FM037_RS18110	COG0159	tryptophan synthase activity
FM037_RS18120	COG4946	Tricorn protease homolog
FM037_RS18120	COG1506	peptidase
FM037_RS18120	COG0823	Involved in the tonB-independent uptake of proteins
FM037_RS18130	COG2917	probably involved in intracellular septation
FM037_RS18145	COG0318	PFAM AMP-dependent synthetase and ligase
FM037_RS18150	COG4977	sequence-specific DNA binding
FM037_RS18155	COG1902	pentaerythritol trinitrate reductase activity
FM037_RS18155	COG0446	pyridine nucleotide-disulphide oxidoreductase
FM037_RS18165	COG2203	Gaf domain
FM037_RS18165	COG3706	GGDEF domain
FM037_RS18165	COG4251	negative regulation of phosphorylation
FM037_RS18165	COG5001	Diguanylate cyclase
FM037_RS18205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM037_RS18220	COG0604	alcohol dehydrogenase
FM037_RS18225	COG0583	DNA-binding transcription factor activity
FM037_RS18230	COG2137	regulation of response to DNA damage stimulus
FM037_RS18245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FM037_RS18265	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FM037_RS18315	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FM037_RS18330	COG0456	acetyltransferase
FM037_RS18355	COG0583	DNA-binding transcription factor activity
FM037_RS18395	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FM037_RS18400	COG1286	toxin biosynthetic process
FM037_RS18405	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FM037_RS18410	COG0285	dihydrofolate synthase activity
FM037_RS18415	COG0101	tRNA pseudouridine synthase activity
FM037_RS18425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FM037_RS18430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FM037_RS18435	COG2977	Belongs to the P-Pant transferase superfamily
FM037_RS18445	COG1917	Cupin 2, conserved barrel domain protein
FM037_RS18445	COG4977	sequence-specific DNA binding
FM037_RS18450	COG4771	TonB-dependent receptor
FM037_RS18480	COG1169	isochorismate synthase
FM037_RS18485	COG1021	2,3-dihydroxybenzoate-AMP ligase
FM037_RS18490	COG1132	(ABC) transporter
FM037_RS18500	COG1063	alcohol dehydrogenase
FM037_RS18510	COG0826	peptidase U32
FM037_RS18515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FM037_RS18555	COG2890	protein-(glutamine-N5) methyltransferase activity
FM037_RS18560	COG2840	Smr protein MutS2
FM037_RS18565	COG2062	phosphohistidine phosphatase, SixA
FM037_RS18570	COG1025	Belongs to the peptidase M16 family
FM037_RS18575	COG5001	Diguanylate cyclase
FM037_RS18575	COG3300	MHYT domain
FM037_RS18595	COG1250	3-hydroxyacyl-CoA dehydrogenase
FM037_RS18595	COG1024	Enoyl-CoA hydratase
FM037_RS18600	COG0183	Belongs to the thiolase family
FM037_RS18605	COG0714	Associated with various cellular activities
FM037_RS18625	COG2304	oxidoreductase activity
FM037_RS18635	COG1595	DNA-templated transcription, initiation
FM037_RS18650	COG2067	long-chain fatty acid transport protein
FM037_RS18660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM037_RS18670	COG4628	conserved protein (DUF2132)
FM037_RS18695	COG0604	alcohol dehydrogenase
FM037_RS18695	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS18695	COG3321	synthase
FM037_RS18710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FM037_RS18720	COG0602	queuosine metabolic process
FM037_RS18735	COG1846	Transcriptional regulator
FM037_RS18740	COG2130	NADP-dependent
FM037_RS18745	COG1752	Esterase of the alpha-beta hydrolase superfamily
FM037_RS18755	COG0513	Belongs to the DEAD box helicase family
FM037_RS18765	COG1451	nucleotide metabolic process
FM037_RS18770	COG0739	heme binding
FM037_RS18775	COG0419	ATPase involved in DNA repair
FM037_RS18790	COG0745	RESPONSE REGULATOR receiver
FM037_RS18800	COG3977	Valine--pyruvate aminotransferase
FM037_RS18805	COG1278	Cold shock
FM037_RS18810	COG0730	response to heat
FM037_RS18815	COG0583	DNA-binding transcription factor activity
FM037_RS18820	COG0515	serine threonine protein kinase
FM037_RS18835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM037_RS18840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FM037_RS18865	COG0848	biopolymer transport protein
FM037_RS18870	COG0811	peptide transport
FM037_RS18875	COG0811	peptide transport
FM037_RS18900	COG1199	ATP-dependent helicase activity
FM037_RS18905	COG0730	response to heat
FM037_RS18915	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FM037_RS18930	COG1555	photosystem II stabilization
FM037_RS18930	COG1596	polysaccharide export
FM037_RS18935	COG0471	metal ion transport
FM037_RS18945	COG3768	UPF0283 membrane protein
FM037_RS18965	COG1842	Phage shock protein A
FM037_RS18970	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FM037_RS18975	COG0747	negative chemotaxis
FM037_RS18980	COG4168	peptide transport system, permease
FM037_RS18985	COG4171	peptide transport system, permease
FM037_RS18995	COG4172	Belongs to the ABC transporter superfamily
FM037_RS19000	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FM037_RS19005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FM037_RS19015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FM037_RS19020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FM037_RS19025	COG0740	serine-type endopeptidase activity
FM037_RS19030	COG0544	peptidyl-prolyl cis-trans isomerase activity
FM037_RS19050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FM037_RS19055	COG0215	cysteine-tRNA ligase activity
FM037_RS19060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FM037_RS19065	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FM037_RS19080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FM037_RS19140	COG1573	uracil-dna glycosylase
FM037_RS19145	COG3706	GGDEF domain
FM037_RS19155	COG3835	regulator
FM037_RS19160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM037_RS19210	COG0583	DNA-binding transcription factor activity
FM037_RS19220	COG1929	Belongs to the glycerate kinase type-1 family
FM037_RS19225	COG0076	glutamate decarboxylase activity
FM037_RS19245	COG1121	(ABC) transporter
FM037_RS19250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FM037_RS19255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FM037_RS19265	COG3011	Protein conserved in bacteria
FM037_RS19320	COG0612	Peptidase, M16
FM037_RS19350	COG0776	regulation of translation
FM037_RS19365	COG2076	Multidrug Resistance protein
FM037_RS19370	COG0564	pseudouridine synthase activity
FM037_RS19405	COG3059	membrane
FM037_RS19435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FM037_RS19440	COG0318	PFAM AMP-dependent synthetase and ligase
FM037_RS19445	COG0596	Alpha beta hydrolase
FM037_RS19450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FM037_RS19480	COG0704	Plays a role in the regulation of phosphate uptake
FM037_RS19485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FM037_RS19490	COG0581	inorganic phosphate transmembrane transporter activity
FM037_RS19520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FM037_RS19550	COG1957	nucleoside hydrolase
FM037_RS19560	COG3341	Caulimovirus viroplasmin
FM037_RS19560	COG0328	RNA-DNA hybrid ribonuclease activity
FM037_RS19575	COG0583	DNA-binding transcription factor activity
FM037_RS19590	COG0583	DNA-binding transcription factor activity
FM037_RS19620	COG3483	tryptophan 2,3-dioxygenase activity
FM037_RS19625	COG0384	phenazine biosynthesis protein PhzF
FM037_RS19640	COG1073	alpha beta
FM037_RS19645	COG2226	methyltransferase
FM037_RS19650	COG0346	lactoylglutathione lyase activity
FM037_RS19680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FM037_RS19685	COG0372	Belongs to the citrate synthase family
FM037_RS19690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FM037_RS19705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FM037_RS19710	COG0488	(ABC) transporter
FM037_RS19715	COG2608	mercury ion transmembrane transporter activity
FM037_RS19715	COG2217	Heavy metal translocating P-type atpase
FM037_RS19735	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS19745	COG1024	Enoyl-CoA hydratase
FM037_RS19755	COG1960	acyl-CoA dehydrogenase activity
FM037_RS19780	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FM037_RS19820	COG3047	cAMP biosynthetic process
FM037_RS19840	COG1946	Acyl-CoA thioesterase
FM037_RS19845	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS19850	COG1575	Belongs to the MenA family. Type 1 subfamily
FM037_RS19875	COG0826	peptidase U32
FM037_RS19890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FM037_RS19905	COG3501	Rhs element vgr protein
FM037_RS19915	COG0564	pseudouridine synthase activity
FM037_RS19920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FM037_RS19935	COG1960	acyl-CoA dehydrogenase activity
FM037_RS19940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FM037_RS19945	COG1024	Enoyl-CoA hydratase
FM037_RS19950	COG4770	biotin carboxylase activity
FM037_RS19965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FM037_RS19980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FM037_RS19990	COG1435	thymidine kinase activity
FM037_RS19995	COG1757	Na H antiporter
FM037_RS20015	COG0804	urea catabolic process
FM037_RS20030	COG1720	tRNA m6t6A37 methyltransferase activity
FM037_RS20035	COG0110	maltose O-acetyltransferase activity
FM037_RS20070	COG0442	prolyl-tRNA aminoacylation
FM037_RS20095	COG3706	GGDEF domain
FM037_RS20105	COG0587	DNA-directed DNA polymerase activity
FM037_RS20110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FM037_RS20115	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FM037_RS20120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FM037_RS20125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FM037_RS20145	COG0750	zinc metalloprotease
FM037_RS20150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FM037_RS20155	COG0575	Belongs to the CDS family
FM037_RS20160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FM037_RS20165	COG0233	cytoplasmic translational termination
FM037_RS20170	COG0528	UMP kinase activity
FM037_RS20175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FM037_RS20180	COG0052	Belongs to the universal ribosomal protein uS2 family
FM037_RS20185	COG0024	Methionine aminopeptidase
FM037_RS20190	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FM037_RS20195	COG2171	N-acyltransferase activity
FM037_RS20210	COG0788	formyltetrahydrofolate deformylase activity
FM037_RS20220	COG0716	FMN binding
FM037_RS20230	COG0564	pseudouridine synthase activity
FM037_RS20235	COG3098	single-species biofilm formation
FM037_RS20275	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FM037_RS20290	COG0583	DNA-binding transcription factor activity
FM037_RS20295	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FM037_RS20305	COG2091	lysine biosynthetic process via aminoadipic acid
FM037_RS20335	COG1136	(ABC) transporter
FM037_RS20335	COG0577	efflux transmembrane transporter activity
FM037_RS20360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM037_RS20365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS20380	COG3710	Transcriptional regulator
FM037_RS20410	COG2070	2-Nitropropane dioxygenase
FM037_RS20410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FM037_RS20420	COG2233	PERMEase
FM037_RS20445	COG0583	DNA-binding transcription factor activity
FM037_RS20450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FM037_RS20490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM037_RS20510	COG1566	PFAM secretion protein HlyD family protein
FM037_RS20515	COG0583	DNA-binding transcription factor activity
FM037_RS20530	COG3291	Pkd domain containing protein
FM037_RS20535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FM037_RS20600	COG0745	RESPONSE REGULATOR receiver
FM037_RS20610	COG2974	May be involved in recombination
FM037_RS20630	COG1611	Belongs to the LOG family
FM037_RS20635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FM037_RS20645	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS20655	COG2095	MarC family integral membrane protein
FM037_RS20660	COG1506	peptidase
FM037_RS20660	COG0823	Involved in the tonB-independent uptake of proteins
FM037_RS20660	COG4946	Tricorn protease homolog
FM037_RS20665	COG0473	3-isopropylmalate dehydrogenase activity
FM037_RS20670	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FM037_RS20685	COG0583	DNA-binding transcription factor activity
FM037_RS20695	COG0301	tRNA thio-modification
FM037_RS20695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM037_RS20705	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FM037_RS20710	COG1722	exodeoxyribonuclease VII activity
FM037_RS20715	COG0142	geranyltranstransferase activity
FM037_RS20720	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FM037_RS20725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FM037_RS20730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FM037_RS20740	COG0523	cobalamin synthesis protein
FM037_RS20800	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FM037_RS20805	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FM037_RS20815	COG1805	sodium ion transport
FM037_RS20820	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FM037_RS20835	COG4232	protein-disulfide reductase activity
FM037_RS20930	COG1404	Belongs to the peptidase S8 family
FM037_RS20945	COG3314	Sporulation integral membrane protein YlbJ
FM037_RS20955	COG0625	glutathione transferase activity
FM037_RS20960	COG3097	Belongs to the UPF0267 family
FM037_RS20965	COG0840	transmembrane signaling receptor activity
FM037_RS20980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FM037_RS20980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FM037_RS21000	COG0386	Belongs to the glutathione peroxidase family
FM037_RS21005	COG3291	Pkd domain containing protein
FM037_RS21050	COG1454	alcohol dehydrogenase
FM037_RS21065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS21085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FM037_RS21090	COG1607	acyl-coa hydrolase
FM037_RS21100	COG1785	Belongs to the alkaline phosphatase family
FM037_RS21110	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FM037_RS21115	COG2860	membrane
FM037_RS21120	COG0668	transmembrane transport
FM037_RS21135	COG0583	DNA-binding transcription factor activity
FM037_RS21155	COG0023	Translation Initiation Factor
FM037_RS21160	COG1678	Uncharacterized ACR, COG1678
FM037_RS21165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FM037_RS21185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FM037_RS21190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FM037_RS21195	COG0762	integral membrane protein
FM037_RS21205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FM037_RS21210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FM037_RS21220	COG0583	DNA-binding transcription factor activity
FM037_RS21230	COG2066	Belongs to the glutaminase family
FM037_RS21235	COG3171	Protein conserved in bacteria
FM037_RS21240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FM037_RS21245	COG1194	a g-specific adenine glycosylase
FM037_RS21250	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FM037_RS21255	COG2353	YceI-like domain
FM037_RS21260	COG3038	cytochrome b561
FM037_RS21285	COG0738	Major facilitator superfamily
FM037_RS21295	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FM037_RS21300	COG2971	BadF BadG BcrA BcrD
FM037_RS21335	COG1609	Transcriptional regulator
FM037_RS21385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FM037_RS21390	COG1047	Peptidyl-prolyl cis-trans
FM037_RS21395	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FM037_RS21400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FM037_RS21405	COG0196	riboflavin kinase activity
FM037_RS21415	COG0268	Binds directly to 16S ribosomal RNA
FM037_RS21420	COG0640	Transcriptional regulator
FM037_RS21435	COG3022	response to hydroperoxide
FM037_RS21440	COG1115	amino acid carrier protein
FM037_RS21445	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FM037_RS21455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FM037_RS21460	COG0166	Belongs to the GPI family
FM037_RS21475	COG0745	RESPONSE REGULATOR receiver
FM037_RS21480	COG4191	Histidine kinase
FM037_RS21480	COG0784	Response regulator, receiver
FM037_RS21485	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FM037_RS21495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FM037_RS21500	COG0083	homoserine kinase activity
FM037_RS21505	COG0527	aspartate kinase activity
FM037_RS21505	COG0460	homoserine dehydrogenase
FM037_RS21510	COG1047	Peptidyl-prolyl cis-trans
FM037_RS21520	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FM037_RS21535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FM037_RS21550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FM037_RS21555	COG1151	hydroxylamine reductase activity
FM037_RS21560	COG0287	Prephenate dehydrogenase
FM037_RS21560	COG1605	Chorismate mutase
FM037_RS21565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FM037_RS21570	COG0335	large ribosomal subunit rRNA binding
FM037_RS21575	COG0336	Belongs to the RNA methyltransferase TrmD family
FM037_RS21580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FM037_RS21585	COG0228	four-way junction DNA binding
FM037_RS21590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FM037_RS21595	COG4137	Cytochrome C assembly protein
FM037_RS21600	COG4536	flavin adenine dinucleotide binding
FM037_RS21615	COG0583	DNA-binding transcription factor activity
FM037_RS21620	COG3048	D-serine ammonia-lyase activity
FM037_RS21625	COG2610	gluconate transmembrane transporter activity
FM037_RS21635	COG0736	holo-[acyl-carrier-protein] synthase activity
FM037_RS21640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FM037_RS21660	COG0571	ribonuclease III activity
FM037_RS21670	COG0481	GTPase activity
FM037_RS21675	COG3086	response to oxidative stress
FM037_RS21690	COG1595	DNA-templated transcription, initiation
FM037_RS21695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FM037_RS21705	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FM037_RS21710	COG0583	DNA-binding transcription factor activity
FM037_RS21720	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FM037_RS21725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FM037_RS21730	COG0730	response to heat
FM037_RS21735	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FM037_RS21740	COG0494	nUDIX hydrolase
FM037_RS21745	COG3066	DNA modification
FM037_RS21755	COG0583	DNA-binding transcription factor activity
FM037_RS21765	COG2198	Histidine kinase
FM037_RS21765	COG5002	protein histidine kinase activity
FM037_RS21765	COG0784	Response regulator, receiver
FM037_RS21770	COG1242	4 iron, 4 sulfur cluster binding
FM037_RS21780	COG0493	'glutamate synthase
FM037_RS21785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FM037_RS21920	COG4790	Type iii secretion
FM037_RS21930	COG3710	Transcriptional regulator
FM037_RS21960	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FM037_RS22040	COG3104	oligopeptide transport
FM037_RS22055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FM037_RS22060	COG0739	heme binding
FM037_RS22060	COG0741	lytic transglycosylase activity
FM037_RS22060	COG1196	nuclear chromosome segregation
FM037_RS22065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FM037_RS22075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FM037_RS22090	COG0316	Belongs to the HesB IscA family
FM037_RS22110	COG0861	Integral membrane protein TerC family
FM037_RS22145	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FM037_RS22165	COG3267	Type II secretory pathway component ExeA
FM037_RS22165	COG3409	Peptidoglycan-binding domain 1 protein
FM037_RS22170	COG0617	tRNA 3'-terminal CCA addition
FM037_RS22180	COG1388	LysM domain
FM037_RS22180	COG1376	ErfK ybiS ycfS ynhG family protein
FM037_RS22185	COG2226	methyltransferase
FM037_RS22190	COG1968	undecaprenyl-diphosphatase activity
FM037_RS22200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FM037_RS22205	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FM037_RS22210	COG4206	TonB-dependent receptor
FM037_RS22215	COG3682	Transcriptional regulator
FM037_RS22225	COG3152	Membrane
FM037_RS22235	COG1228	amidohydrolase
FM037_RS22265	COG3447	MASE1 domain protein
FM037_RS22265	COG5002	protein histidine kinase activity
FM037_RS22265	COG5001	Diguanylate cyclase
FM037_RS22275	COG1070	Carbohydrate kinase
FM037_RS22290	COG2814	Major facilitator Superfamily
FM037_RS22295	COG0583	DNA-binding transcription factor activity
FM037_RS22425	COG3119	arylsulfatase activity
FM037_RS22430	COG0418	dihydroorotase activity
FM037_RS22435	COG5001	Diguanylate cyclase
FM037_RS22435	COG3706	GGDEF domain
FM037_RS22435	COG2203	Gaf domain
FM037_RS22435	COG4251	negative regulation of phosphorylation
FM037_RS22455	COG2319	Wd-40 repeat
FM037_RS22455	COG4249	Peptidase C14 caspase catalytic subunit p20
FM037_RS22470	COG1595	DNA-templated transcription, initiation
FM037_RS22475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FM037_RS22495	COG2267	carboxylic ester hydrolase activity
FM037_RS22505	COG1966	Carbon starvation protein
FM037_RS22510	COG4783	chaperone-mediated protein folding
FM037_RS22525	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FM037_RS22535	COG0625	glutathione transferase activity
FM037_RS22540	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FM037_RS22550	COG4628	conserved protein (DUF2132)
FM037_RS22555	COG1280	lysine exporter protein (LysE YggA)
FM037_RS22570	COG3590	peptidase
FM037_RS22575	COG0625	glutathione transferase activity
FM037_RS22585	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FM037_RS22590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FM037_RS22605	COG2837	iron assimilation
FM037_RS22610	COG3842	ATPase activity
FM037_RS22615	COG0395	ABC-type sugar transport system, permease component
FM037_RS22620	COG1840	ABC-type Fe3 transport system, periplasmic component
FM037_RS22630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FM037_RS22655	COG5265	(ABC) transporter
FM037_RS22695	COG0347	Belongs to the P(II) protein family
FM037_RS22700	COG0795	lipopolysaccharide-transporting ATPase activity
FM037_RS22705	COG0795	lipopolysaccharide-transporting ATPase activity
FM037_RS22710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FM037_RS22720	COG0583	DNA-binding transcription factor activity
FM037_RS22725	COG1280	lysine exporter protein (LysE YggA)
FM037_RS22760	COG2927	DNA polymerase III (CHI subunit)
FM037_RS22765	COG0525	valine-tRNA ligase activity
FM037_RS22775	COG1355	regulation of microtubule-based process
FM037_RS22785	COG0840	transmembrane signaling receptor activity
FM037_RS22800	COG1584	GPR1 FUN34 yaaH family protein
FM037_RS22830	COG3615	Tellurite resistance protein tehB
FM037_RS22865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FM037_RS22870	COG0022	dehydrogenase e1 component
FM037_RS22875	COG1960	acyl-CoA dehydrogenase activity
FM037_RS22895	COG0745	RESPONSE REGULATOR receiver
FM037_RS22905	COG3313	Fe-S protein
FM037_RS22915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FM037_RS22920	COG1566	PFAM secretion protein HlyD family protein
FM037_RS22930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FM037_RS22940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FM037_RS22945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FM037_RS22965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FM037_RS22970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FM037_RS22975	COG2967	ApaG domain
FM037_RS22980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FM037_RS23000	COG3610	response to peptide
FM037_RS23005	COG2966	Psort location CytoplasmicMembrane, score
FM037_RS23010	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FM037_RS23015	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FM037_RS23020	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FM037_RS23025	COG0142	geranyltranstransferase activity
FM037_RS23030	COG0039	L-malate dehydrogenase activity
FM037_RS23035	COG1438	arginine binding
FM037_RS23055	COG1278	Cold shock
FM037_RS23090	COG1253	flavin adenine dinucleotide binding
FM037_RS23140	COG0583	DNA-binding transcription factor activity
FM037_RS23150	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FM037_RS23150	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FM037_RS23155	COG0509	glycine decarboxylation via glycine cleavage system
FM037_RS23160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FM037_RS23165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FM037_RS23180	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FM037_RS23205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FM037_RS23215	COG3015	lipoprotein NlpE involved in copper resistance
FM037_RS23220	COG3291	Pkd domain containing protein
FM037_RS23225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FM037_RS23230	COG2165	general secretion pathway protein
FM037_RS23260	COG0348	domain, Protein
FM037_RS23280	COG3547	Transposase (IS116 IS110 IS902 family)
FM037_RS23290	COG1522	sequence-specific DNA binding
FM037_RS23295	COG1132	(ABC) transporter
FM037_RS23300	COG0748	coenzyme F420 binding
FM037_RS23305	COG3721	Heme iron utilization protein
FM037_RS23315	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FM037_RS23320	COG0811	peptide transport
FM037_RS23325	COG0848	biopolymer transport protein
FM037_RS23330	COG4558	Periplasmic binding protein
FM037_RS23335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM037_RS23360	COG0778	Nitroreductase
FM037_RS23370	COG0363	glucosamine-6-phosphate deaminase activity
FM037_RS23375	COG1187	pseudouridine synthase activity
FM037_RS23390	COG0004	ammonium transporteR
FM037_RS23405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FM037_RS23425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FM037_RS23450	COG0840	transmembrane signaling receptor activity
FM037_RS23465	COG2203	Gaf domain
FM037_RS23465	COG3706	GGDEF domain
FM037_RS23465	COG4251	negative regulation of phosphorylation
FM037_RS23465	COG5001	Diguanylate cyclase
FM037_RS23470	COG3634	alkyl hydroperoxide reductase activity
FM037_RS23490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FM037_RS23520	COG0564	pseudouridine synthase activity
FM037_RS23525	COG1522	sequence-specific DNA binding
FM037_RS23550	COG0745	RESPONSE REGULATOR receiver
FM037_RS23560	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FM037_RS23565	COG1053	succinate dehydrogenase
FM037_RS23570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM037_RS23570	COG4191	Histidine kinase
FM037_RS23575	COG2204	response regulator
FM037_RS23615	COG1115	amino acid carrier protein
FM037_RS23625	COG4772	TonB-dependent receptor
FM037_RS23630	COG1730	sister chromatid segregation
FM037_RS23655	COG3501	Rhs element vgr protein
FM037_RS23680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FM037_RS23685	COG1643	Atp-dependent helicase
FM037_RS23715	COG1489	DNA binding
FM037_RS23720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FM037_RS23725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FM037_RS23735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FM037_RS23740	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FM037_RS23745	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FM037_RS23760	COG0842	Transport permease protein
FM037_RS23775	COG0163	prenyltransferase activity
FM037_RS23780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FM037_RS23785	COG0390	transport system, permease component
FM037_RS23790	COG1335	isochorismatase
FM037_RS23800	COG0583	DNA-binding transcription factor activity
FM037_RS23825	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FM037_RS23840	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FM037_RS23865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FM037_RS23870	COG3025	triphosphatase activity
FM037_RS23875	COG1392	Phosphate transport regulator
FM037_RS23880	COG0306	phosphate transporter
FM037_RS23885	COG4991	sh3 domain protein
FM037_RS23900	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FM037_RS23905	COG4988	ABC transporter
FM037_RS23920	COG0513	Belongs to the DEAD box helicase family
FM037_RS23940	COG0513	Belongs to the DEAD box helicase family
FM037_RS23955	COG0840	transmembrane signaling receptor activity
FM037_RS23975	COG3335	DDE superfamily endonuclease
FM037_RS24035	COG4191	Histidine kinase
FM037_RS24035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM037_RS24040	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FM037_RS24055	COG0500	methyltransferase
FM037_RS24075	COG1324	tolerance protein
FM037_RS24080	COG4232	protein-disulfide reductase activity
FM037_RS24085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FM037_RS24085	COG4651	solute:proton antiporter activity
FM037_RS24095	COG3250	beta-galactosidase activity
FM037_RS24100	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FM037_RS24105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FM037_RS24120	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS24120	COG3321	synthase
FM037_RS24120	COG0604	alcohol dehydrogenase
FM037_RS24125	COG3291	Pkd domain containing protein
FM037_RS24170	COG2814	Major facilitator Superfamily
FM037_RS24210	COG0583	DNA-binding transcription factor activity
FM037_RS24225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FM037_RS24240	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FM037_RS24245	COG0460	homoserine dehydrogenase
FM037_RS24245	COG0527	aspartate kinase activity
FM037_RS24250	COG0626	cystathionine gamma-synthase activity
FM037_RS24255	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FM037_RS24270	COG2885	chlorophyll binding
FM037_RS24320	COG4964	Belongs to the GSP D family
FM037_RS24350	COG0583	DNA-binding transcription factor activity
FM037_RS24365	COG1773	rubredoxin
FM037_RS24365	COG0426	domain, Protein
FM037_RS24390	COG3301	Polysulphide reductase, NrfD
FM037_RS24395	COG0437	4 iron, 4 sulfur cluster binding
FM037_RS24425	COG1902	pentaerythritol trinitrate reductase activity
FM037_RS24430	COG0583	DNA-binding transcription factor activity
FM037_RS24445	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FM037_RS24510	COG2731	YhcH YjgK YiaL family protein
FM037_RS24520	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FM037_RS24740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FM037_RS24745	COG0511	ligase activity, forming carbon-carbon bonds
FM037_RS24750	COG0439	Biotin carboxylase
FM037_RS24815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FM037_RS24840	COG0010	Belongs to the arginase family
FM037_RS24850	COG0583	DNA-binding transcription factor activity
FM037_RS24855	COG2226	methyltransferase
FM037_RS24870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FM037_RS24875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FM037_RS24880	COG0805	protein transport
FM037_RS24890	COG0084	hydrolase, TatD family'
FM037_RS24895	COG5001	Diguanylate cyclase
FM037_RS24895	COG4251	negative regulation of phosphorylation
FM037_RS24895	COG3706	GGDEF domain
FM037_RS24895	COG2203	Gaf domain
FM037_RS24920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS24925	COG1538	Outer membrane efflux protein
FM037_RS24950	COG0248	Ppx GppA phosphatase
FM037_RS24955	COG0513	Belongs to the DEAD box helicase family
FM037_RS24960	COG3118	belongs to the thioredoxin family
FM037_RS24975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FM037_RS24980	COG1053	succinate dehydrogenase
FM037_RS24995	COG2264	protein methyltransferase activity
FM037_RS25000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FM037_RS25005	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FM037_RS25010	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FM037_RS25015	COG1011	Hydrolase
FM037_RS25020	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FM037_RS25030	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FM037_RS25035	COG0019	diaminopimelate decarboxylase activity
FM037_RS25050	COG3072	Adenylate cyclase
FM037_RS25055	COG0181	hydroxymethylbilane synthase activity
FM037_RS25060	COG1587	Uroporphyrinogen-III synthase
FM037_RS25065	COG2959	enzyme of heme biosynthesis
FM037_RS25195	COG1538	Outer membrane efflux protein
FM037_RS25250	COG1309	transcriptional regulator
FM037_RS25255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM037_RS25275	COG4452	Inner membrane protein CreD
FM037_RS25280	COG0671	phosphoesterase, PA-phosphatase related
FM037_RS25285	COG1522	sequence-specific DNA binding
FM037_RS25290	COG0733	neurotransmitter:sodium symporter activity
FM037_RS25295	COG1309	transcriptional regulator
FM037_RS25310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FM037_RS25320	COG0129	dihydroxy-acid dehydratase activity
FM037_RS25325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FM037_RS25330	COG3978	acetolactate synthase activity
FM037_RS25345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FM037_RS25360	COG3706	GGDEF domain
FM037_RS25365	COG1045	serine acetyltransferase
FM037_RS25385	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FM037_RS25390	COG0210	DNA helicase
FM037_RS25395	COG0251	oxidation-reduction process
FM037_RS25415	COG0330	HflC and HflK could
FM037_RS25420	COG0330	HflC and HflK could
FM037_RS25435	COG1473	amidohydrolase
FM037_RS25440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FM037_RS25450	COG2964	Protein conserved in bacteria
FM037_RS25455	COG0251	oxidation-reduction process
FM037_RS25460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FM037_RS25485	COG0668	transmembrane transport
FM037_RS25515	COG2153	protein acetylation
FM037_RS25520	COG0641	radical SAM
FM037_RS25540	COG3119	arylsulfatase activity
FM037_RS25550	COG0583	DNA-binding transcription factor activity
FM037_RS25575	COG2358	TRAP transporter, solute receptor (TAXI family
FM037_RS25580	COG0217	transcriptional regulatory protein
FM037_RS25605	COG0789	Transcriptional regulator
FM037_RS25610	COG0138	bifunctional purine biosynthesis protein purh
FM037_RS25615	COG0151	Belongs to the GarS family
FM037_RS25630	COG4221	oxidoreductase activity
FM037_RS25635	COG5001	Diguanylate cyclase
FM037_RS25635	COG5002	protein histidine kinase activity
FM037_RS25650	COG0745	RESPONSE REGULATOR receiver
FM037_RS25655	COG5002	protein histidine kinase activity
FM037_RS25660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FM037_RS25695	COG1011	Hydrolase
FM037_RS25730	COG0835	chemotaxis
FM037_RS25730	COG0784	Response regulator, receiver
FM037_RS25755	COG3655	Transcriptional regulator
FM037_RS25770	COG1757	Na H antiporter
FM037_RS25775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FM037_RS25800	COG3547	Transposase (IS116 IS110 IS902 family)
FM037_RS25855	COG1979	alcohol dehydrogenase
FM037_RS25860	COG1309	transcriptional regulator
FM037_RS25870	COG3243	poly(R)-hydroxyalkanoic acid synthase
FM037_RS25885	COG0204	Acyl-transferase
FM037_RS25890	COG0204	Acyl-transferase
FM037_RS25900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FM037_RS25935	COG3074	FtsZ-dependent cytokinesis
FM037_RS25945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FM037_RS25950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FM037_RS26015	COG0243	molybdopterin cofactor binding
FM037_RS26020	COG0437	4 iron, 4 sulfur cluster binding
FM037_RS26025	COG3381	protein complex oligomerization
FM037_RS26045	COG1335	isochorismatase
FM037_RS26055	COG1032	radical SAM domain protein
FM037_RS26115	COG0653	protein targeting
FM037_RS26120	COG0739	heme binding
FM037_RS26130	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FM037_RS26135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FM037_RS26140	COG0849	cell division
FM037_RS26145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FM037_RS26150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FM037_RS26155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FM037_RS26160	COG0772	Belongs to the SEDS family
FM037_RS26165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FM037_RS26175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FM037_RS26180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FM037_RS26185	COG0768	penicillin binding
FM037_RS26190	COG3116	cell division
FM037_RS26195	COG0275	rRNA processing
FM037_RS26200	COG2001	Belongs to the MraZ family
FM037_RS26210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FM037_RS26220	COG2067	long-chain fatty acid transport protein
FM037_RS26225	COG0066	3-isopropylmalate dehydratase activity
FM037_RS26230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FM037_RS26235	COG0473	3-isopropylmalate dehydrogenase activity
FM037_RS26240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FM037_RS26250	COG0514	ATP-dependent DNA helicase (RecQ)
FM037_RS26255	COG2050	protein possibly involved in aromatic compounds catabolism
FM037_RS26260	COG2962	Rard protein
FM037_RS26270	COG4771	TonB-dependent receptor
FM037_RS26290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FM037_RS26290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FM037_RS26295	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FM037_RS26300	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FM037_RS26305	COG2003	Belongs to the UPF0758 family
FM037_RS26310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FM037_RS26315	COG0756	dUTP diphosphatase activity
FM037_RS26320	COG1309	transcriptional regulator
FM037_RS26330	COG0302	gtp cyclohydrolase
FM037_RS26335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FM037_RS26340	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FM037_RS26345	COG1561	YicC-like family, N-terminal region
FM037_RS26390	COG1758	RNA polymerase activity
FM037_RS26395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FM037_RS26405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FM037_RS26410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM037_RS26410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM037_RS26415	COG1022	Amp-dependent synthetase and ligase
FM037_RS26430	COG4585	Histidine kinase
FM037_RS26435	COG2197	response regulator
FM037_RS26440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FM037_RS26465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FM037_RS26470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FM037_RS26485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FM037_RS26495	COG2986	histidine ammonia-lyase
FM037_RS26535	COG1028	Short-chain dehydrogenase reductase Sdr
FM037_RS26545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FM037_RS26555	COG0456	acetyltransferase
FM037_RS26560	COG1490	D-aminoacyl-tRNA deacylase activity
FM037_RS26575	COG1295	ribonuclease BN
FM037_RS26600	COG1217	gtp-binding protein TYPA
FM037_RS26605	COG0174	glutamine synthetase
FM037_RS26625	COG3852	Histidine kinase
FM037_RS26630	COG2204	response regulator
FM037_RS26650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FM037_RS26655	COG3088	subunit of a heme lyase
FM037_RS26655	COG4235	cytochrome complex assembly
FM037_RS26670	COG4235	cytochrome complex assembly
FM037_RS26670	COG3088	subunit of a heme lyase
FM037_RS26675	COG3245	cytochrome
FM037_RS26685	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FM037_RS26690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FM037_RS26695	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FM037_RS26700	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FM037_RS26710	COG0203	ribosomal protein L17
FM037_RS26715	COG0202	RNA polymerase activity
FM037_RS26720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FM037_RS26725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FM037_RS26730	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FM037_RS26740	COG0201	protein transport
FM037_RS26745	COG0200	Binds to the 23S rRNA
FM037_RS26750	COG1841	ribosomal large subunit assembly
FM037_RS26755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FM037_RS26760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FM037_RS26765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FM037_RS26770	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FM037_RS26775	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FM037_RS26780	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FM037_RS26790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FM037_RS26795	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FM037_RS26800	COG0255	Belongs to the universal ribosomal protein uL29 family
FM037_RS26805	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FM037_RS26810	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FM037_RS26815	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FM037_RS26820	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FM037_RS26825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FM037_RS26830	COG0089	rRNA binding
FM037_RS26835	COG0088	Forms part of the polypeptide exit tunnel
FM037_RS26840	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FM037_RS26845	COG0051	transcription antitermination factor activity, RNA binding
FM037_RS26850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FM037_RS26860	COG0049	tRNA binding
FM037_RS26865	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FM037_RS26880	COG0222	ribosome binding
FM037_RS26885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FM037_RS26890	COG0081	regulation of translation
FM037_RS26895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FM037_RS26910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FM037_RS26930	COG1072	(Pantothenic acid kinase))
FM037_RS26980	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FM037_RS26985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FM037_RS27000	COG0709	Synthesizes selenophosphate from selenide and ATP
FM037_RS27005	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FM037_RS27015	COG1218	3'(2'),5'-bisphosphate nucleotidase
FM037_RS27020	COG0494	nUDIX hydrolase
FM037_RS27025	COG1011	Hydrolase
FM037_RS27045	COG3156	type II secretion system protein K
FM037_RS27055	COG2165	general secretion pathway protein
FM037_RS27065	COG2165	general secretion pathway protein
FM037_RS27070	COG1459	type II secretion system
FM037_RS27075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FM037_RS27090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FM037_RS27095	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FM037_RS27100	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FM037_RS27125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FM037_RS27135	COG0671	phosphoesterase, PA-phosphatase related
FM037_RS27140	COG0671	phosphoesterase, PA-phosphatase related
FM037_RS27155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FM037_RS27165	COG1528	Iron-storage protein
FM037_RS27180	COG0303	'Molybdopterin
FM037_RS27185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FM037_RS27220	COG3220	belongs to the UPF0276 family
FM037_RS27230	COG0786	glutamate:sodium symporter activity
FM037_RS27245	COG0401	homolog of Blt101
FM037_RS27250	COG0564	pseudouridine synthase activity
FM037_RS27260	COG0745	RESPONSE REGULATOR receiver
FM037_RS27270	COG3111	PFAM Bacterial OB fold (BOF) protein
FM037_RS27275	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FM037_RS27290	COG0314	molybdopterin synthase activity
FM037_RS27295	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FM037_RS27300	COG0315	cyclic pyranopterin monophosphate synthase activity
FM037_RS27305	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FM037_RS27315	COG0840	transmembrane signaling receptor activity
FM037_RS27325	COG2258	MOSC domain
FM037_RS27335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FM037_RS27340	COG0456	acetyltransferase
FM037_RS27360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FM037_RS27370	COG0437	4 iron, 4 sulfur cluster binding
FM037_RS27375	COG0243	molybdopterin cofactor binding
FM037_RS27375	COG3383	formate dehydrogenase (NAD+) activity
FM037_RS27405	COG0437	4 iron, 4 sulfur cluster binding
FM037_RS27420	COG3381	protein complex oligomerization
FM037_RS27475	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FM037_RS27485	COG3161	chorismate lyase activity
FM037_RS27500	COG3408	Glycogen debranching enzyme
FM037_RS27500	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FM037_RS27505	COG2095	MarC family integral membrane protein
FM037_RS27530	COG0204	Acyl-transferase
FM037_RS27690	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FM037_RS27720	COG4790	Type iii secretion
FM037_RS27725	COG4794	Type iii secretion
FM037_RS27730	COG4791	protein targeting
FM037_RS27735	COG4792	protein secretion
FM037_RS27755	COG0668	transmembrane transport
FM037_RS27770	COG2986	histidine ammonia-lyase
FM037_RS27775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FM037_RS27780	COG2188	Transcriptional regulator
FM037_RS27795	COG4977	sequence-specific DNA binding
FM037_RS27795	COG1917	Cupin 2, conserved barrel domain protein
FM037_RS27810	COG4774	siderophore transport
FM037_RS27820	COG1181	Belongs to the D-alanine--D-alanine ligase family
FM037_RS27840	COG0019	diaminopimelate decarboxylase activity
FM037_RS27855	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FM037_RS27880	COG1022	Amp-dependent synthetase and ligase
FM037_RS27895	COG2188	Transcriptional regulator
FM037_RS27905	COG4555	ABC transporter
FM037_RS27910	COG1668	transmembrane transport
FM037_RS27940	COG0521	Mo-molybdopterin cofactor biosynthetic process
FM037_RS27945	COG0791	NLP P60 protein
FM037_RS27950	COG2081	HI0933 family
FM037_RS27955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FM037_RS27960	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FM037_RS27965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM037_RS27970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FM037_RS27975	COG4942	peptidase
FM037_RS27990	COG1959	2 iron, 2 sulfur cluster binding
FM037_RS28040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FM037_RS28045	COG0573	inorganic phosphate transmembrane transporter activity
FM037_RS28050	COG0581	inorganic phosphate transmembrane transporter activity
FM037_RS28055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FM037_RS28065	COG0109	protoheme IX farnesyltransferase activity
FM037_RS28085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FM037_RS28095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FM037_RS28100	COG1349	DNA-binding transcription factor activity
FM037_RS28105	COG4774	siderophore transport
FM037_RS28110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FM037_RS28115	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FM037_RS28120	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FM037_RS28125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FM037_RS28130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FM037_RS28135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FM037_RS28140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FM037_RS28145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FM037_RS28155	COG0356	it plays a direct role in the translocation of protons across the membrane
FM037_RS28165	COG1475	DNA binding
FM037_RS28170	COG1192	Involved in chromosome partitioning
FM037_RS28175	COG0357	Ribosomal RNA small subunit methyltransferase G
FM037_RS28180	COG0445	tRNA wobble uridine modification
FM037_RS28185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FM037_RS28190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FM037_RS28200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FM037_RS28210	COG1845	cytochrome c oxidase, subunit III
FM037_RS28215	COG1845	cytochrome c oxidase, subunit III
FM037_RS28245	COG3214	Protein conserved in bacteria
FM037_RS28250	COG3012	SEC-C Motif Domain Protein
FM037_RS28250	COG3318	Belongs to the UPF0149 family
FM037_RS28290	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FM037_RS28310	COG1643	Atp-dependent helicase
FM037_RS28335	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FM037_RS28340	COG0706	membrane insertase activity
FM037_RS28345	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FM037_RS28350	COG0594	ribonuclease P activity