locus-tag	class	description
FNA65_RS00280	COG2990	Protein conserved in bacteria
FNA65_RS00285	COG0297	glycogen (starch) synthase activity
FNA65_RS00290	COG0726	polysaccharide deacetylase
FNA65_RS00375	COG4372	Transposase
FNA65_RS00380	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS00435	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS00510	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS00515	COG4372	Transposase
FNA65_RS00575	COG4372	Transposase
FNA65_RS00605	COG3344	reverse transcriptase
FNA65_RS00735	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS00745	COG3385	transposase activity
FNA65_RS00845	COG3137	Salt-induced outer membrane protein
FNA65_RS00850	COG1105	Belongs to the carbohydrate kinase PfkB family
FNA65_RS00860	COG3001	Fructosamine kinase
FNA65_RS00870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNA65_RS00875	COG1988	membrane-bound metal-dependent
FNA65_RS00880	COG1823	symporter activity
FNA65_RS00905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FNA65_RS00910	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNA65_RS00920	COG0322	excinuclease ABC activity
FNA65_RS00930	COG3678	ATP-independent chaperone mediated protein folding
FNA65_RS00945	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS00970	COG0708	Exodeoxyribonuclease III
FNA65_RS00995	COG0398	Pfam SNARE associated Golgi protein
FNA65_RS01000	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNA65_RS01005	COG4134	Bacterial extracellular solute-binding protein
FNA65_RS01015	COG4136	ATPase activity
FNA65_RS01020	COG2897	thiosulfate sulfurtransferase activity
FNA65_RS01030	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNA65_RS01050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNA65_RS01070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNA65_RS01075	COG0709	Synthesizes selenophosphate from selenide and ATP
FNA65_RS01080	COG0778	Nitroreductase
FNA65_RS01085	COG0616	signal peptide processing
FNA65_RS01090	COG0252	asparaginase activity
FNA65_RS01095	COG1335	isochorismatase
FNA65_RS01100	COG3139	Protein of unknown function (DUF1315)
FNA65_RS01110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNA65_RS01115	COG3385	transposase activity
FNA65_RS01120	COG0676	glucose-6-phosphate 1-epimerase activity
FNA65_RS01125	COG0656	L-ascorbic acid biosynthetic process
FNA65_RS01130	COG3713	MltA-interacting MipA family protein
FNA65_RS01145	COG2199	diguanylate cyclase activity
FNA65_RS01165	COG2199	diguanylate cyclase activity
FNA65_RS01180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNA65_RS01200	COG2807	transmembrane transport
FNA65_RS01205	COG3189	MarR family transcriptional regulator
FNA65_RS01210	COG3042	response to heat
FNA65_RS01230	COG2261	transglycosylase associated protein
FNA65_RS01260	COG3385	transposase activity
FNA65_RS01270	COG0473	3-isopropylmalate dehydrogenase activity
FNA65_RS01290	COG4638	Rieske (2fe-2S)
FNA65_RS01295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNA65_RS01300	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FNA65_RS01305	COG0318	PFAM AMP-dependent synthetase and ligase
FNA65_RS01310	COG3065	identical protein binding
FNA65_RS01315	COG1214	PFAM Peptidase M22, glycoprotease
FNA65_RS01320	COG1199	ATP-dependent helicase activity
FNA65_RS01325	COG0251	oxidation-reduction process
FNA65_RS01345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNA65_RS01355	COG1760	l-serine dehydratase
FNA65_RS01375	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS01385	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS01385	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNA65_RS01390	COG3715	PTS system
FNA65_RS01395	COG3716	PTS system mannose fructose sorbose family IID component
FNA65_RS01410	COG2226	methyltransferase
FNA65_RS01445	COG1414	Transcriptional regulator
FNA65_RS01450	COG2814	Major facilitator Superfamily
FNA65_RS01460	COG0793	Belongs to the peptidase S41A family
FNA65_RS01470	COG1956	GAF domain-containing protein
FNA65_RS01475	COG2995	paraquat-inducible protein a
FNA65_RS01480	COG3008	intermembrane lipid transfer
FNA65_RS01515	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS01520	COG4372	Transposase
FNA65_RS01555	COG0582	viral genome integration into host DNA
FNA65_RS01565	COG1276	copper resistance
FNA65_RS01570	COG2372	response to copper ion
FNA65_RS01580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNA65_RS01585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNA65_RS01595	COG2979	Protein of unknown function (DUF533)
FNA65_RS01615	COG0800	Aldolase
FNA65_RS01620	COG0129	dihydroxy-acid dehydratase activity
FNA65_RS01625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNA65_RS01635	COG0469	pyruvate kinase activity
FNA65_RS01690	COG1175	transmembrane transport
FNA65_RS01695	COG2182	Extracellular solute-binding protein
FNA65_RS01705	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNA65_RS01730	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS01745	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS01805	COG1403	HNH endonuclease
FNA65_RS01815	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FNA65_RS01820	COG4725	Belongs to the MT-A70-like family
FNA65_RS01830	COG1846	Transcriptional regulator
FNA65_RS01850	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FNA65_RS01865	COG0243	molybdopterin cofactor binding
FNA65_RS01870	COG3005	denitrification pathway
FNA65_RS01880	COG3102	Protein conserved in bacteria
FNA65_RS01910	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FNA65_RS01915	COG0745	RESPONSE REGULATOR receiver
FNA65_RS01925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FNA65_RS01930	COG0840	transmembrane signaling receptor activity
FNA65_RS01935	COG0840	transmembrane signaling receptor activity
FNA65_RS01940	COG0835	chemotaxis
FNA65_RS01945	COG2198	Histidine kinase
FNA65_RS01945	COG0643	Histidine kinase
FNA65_RS02035	COG0582	viral genome integration into host DNA
FNA65_RS02040	COG1177	transmembrane transport
FNA65_RS02045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNA65_RS02055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNA65_RS02075	COG4591	ABC-type transport system involved in lipoprotein release permease component
FNA65_RS02080	COG4763	Acyl-transferase
FNA65_RS02085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FNA65_RS02090	COG1376	ErfK ybiS ycfS ynhG family protein
FNA65_RS02090	COG1388	LysM domain
FNA65_RS02100	COG1309	transcriptional regulator
FNA65_RS02105	COG3134	Outer membrane lipoprotein
FNA65_RS02110	COG1252	NADH dehydrogenase
FNA65_RS02135	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FNA65_RS02140	COG5633	Lipoprotein
FNA65_RS02145	COG0537	adenosine 5'-monophosphoramidase activity
FNA65_RS02150	COG4773	Receptor
FNA65_RS02155	COG1263	PTS System
FNA65_RS02155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNA65_RS02160	COG0084	hydrolase, TatD family'
FNA65_RS02165	COG0470	DNA polymerase III
FNA65_RS02175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FNA65_RS02180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNA65_RS02185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNA65_RS02195	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS02200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNA65_RS02220	COG1399	metal-binding, possibly nucleic acid-binding protein
FNA65_RS02225	COG0424	maF-like protein
FNA65_RS02230	COG0564	pseudouridine synthase activity
FNA65_RS02240	COG1530	ribonuclease E activity
FNA65_RS02245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FNA65_RS02250	COG1256	bacterial-type flagellum assembly
FNA65_RS02275	COG4787	bacterial-type flagellum-dependent cell motility
FNA65_RS02280	COG1749	Flagellar hook protein flgE
FNA65_RS02285	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FNA65_RS02290	COG1558	bacterial-type flagellum-dependent cell motility
FNA65_RS02295	COG1815	bacterial-type flagellum-dependent cell motility
FNA65_RS02300	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FNA65_RS02305	COG2747	anti-sigma28 factor FlgM
FNA65_RS02310	COG3418	PFAM FlgN family protein
FNA65_RS02315	COG0728	peptidoglycan biosynthetic process
FNA65_RS02320	COG0673	inositol 2-dehydrogenase activity
FNA65_RS02330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNA65_RS02340	COG2999	glutathione oxidoreductase activity
FNA65_RS02375	COG3038	cytochrome b561
FNA65_RS02380	COG2353	YceI-like domain
FNA65_RS02400	COG1560	Kdo2-lipid A biosynthetic process
FNA65_RS02415	COG5645	(Lipo)protein
FNA65_RS02420	COG3385	transposase activity
FNA65_RS02425	COG2943	transferase activity, transferring hexosyl groups
FNA65_RS02440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNA65_RS02445	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FNA65_RS02490	COG3381	protein complex oligomerization
FNA65_RS02530	COG1702	phosphate starvation-inducible protein PhoH
FNA65_RS02535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNA65_RS02545	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FNA65_RS02545	COG0506	proline dehydrogenase activity
FNA65_RS02545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FNA65_RS02550	COG1309	transcriptional regulator
FNA65_RS02615	COG0745	RESPONSE REGULATOR receiver
FNA65_RS02630	COG0348	domain, Protein
FNA65_RS02660	COG1278	Cold shock
FNA65_RS02665	COG1278	Cold shock
FNA65_RS02685	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNA65_RS02690	COG1596	polysaccharide export
FNA65_RS02695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNA65_RS02700	COG0489	protein tyrosine kinase activity
FNA65_RS02700	COG3206	protein involved in exopolysaccharide biosynthesis
FNA65_RS02715	COG1294	oxidase, subunit
FNA65_RS02720	COG1271	oxidase subunit
FNA65_RS02725	COG1773	rubredoxin
FNA65_RS02730	COG1999	signal sequence binding
FNA65_RS02735	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FNA65_RS02740	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FNA65_RS02745	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FNA65_RS02750	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FNA65_RS02760	COG0670	Belongs to the BI1 family
FNA65_RS02765	COG2920	part of a sulfur-relay system
FNA65_RS02770	COG1254	Belongs to the acylphosphatase family
FNA65_RS02785	COG1832	CoA-binding protein
FNA65_RS02800	COG0210	DNA helicase
FNA65_RS02805	COG3304	Inner membrane component domain
FNA65_RS02810	COG1289	transmembrane transporter activity
FNA65_RS02835	COG2885	chlorophyll binding
FNA65_RS02835	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FNA65_RS02845	COG1067	ATP-dependent peptidase activity
FNA65_RS02865	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS02870	COG4372	Transposase
FNA65_RS02875	COG3009	Protein conserved in bacteria
FNA65_RS02880	COG3008	intermembrane lipid transfer
FNA65_RS02880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FNA65_RS02885	COG2995	paraquat-inducible protein a
FNA65_RS02890	COG0488	(ABC) transporter
FNA65_RS02900	COG3217	Mosc domain protein beta barrel domain protein
FNA65_RS02900	COG0633	Ferredoxin
FNA65_RS02915	COG3121	Chaperone
FNA65_RS02920	COG3539	Fimbrial protein
FNA65_RS02925	COG3539	Fimbrial protein
FNA65_RS02930	COG3539	Fimbrial protein
FNA65_RS02945	COG3539	Fimbrial protein
FNA65_RS02950	COG0431	NADPH-dependent FMN reductase
FNA65_RS02955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNA65_RS02975	COG0308	aminopeptidase N
FNA65_RS03000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNA65_RS03005	COG3108	Peptidase M15
FNA65_RS03010	COG2989	Protein conserved in bacteria
FNA65_RS03030	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS03055	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FNA65_RS03065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNA65_RS03070	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FNA65_RS03075	COG3173	Aminoglycoside phosphotransferase
FNA65_RS03090	COG3214	Protein conserved in bacteria
FNA65_RS03100	COG1132	(ABC) transporter
FNA65_RS03110	COG4372	Transposase
FNA65_RS03115	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS03135	COG0539	negative regulation of cytoplasmic translation
FNA65_RS03160	COG2323	membrane
FNA65_RS03165	COG1944	ATP diphosphatase activity
FNA65_RS03170	COG2116	formate transmembrane transporter activity
FNA65_RS03175	COG1882	Formate acetyltransferase
FNA65_RS03180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNA65_RS03210	COG3302	dmso reductase anchor subunit
FNA65_RS03215	COG0437	4 iron, 4 sulfur cluster binding
FNA65_RS03230	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FNA65_RS03240	COG1178	ABC-type Fe3 transport system permease component
FNA65_RS03240	COG1674	ftsk spoiiie
FNA65_RS03245	COG1522	sequence-specific DNA binding
FNA65_RS03250	COG0492	ferredoxin-NADP+ reductase activity
FNA65_RS03255	COG4988	ABC transporter
FNA65_RS03260	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FNA65_RS03285	COG0542	response to heat
FNA65_RS03295	COG1278	Cold shock
FNA65_RS03305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNA65_RS03310	COG2990	Protein conserved in bacteria
FNA65_RS03330	COG2431	L-lysine efflux transmembrane transporter activity
FNA65_RS03340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNA65_RS03345	COG0028	Belongs to the TPP enzyme family
FNA65_RS03350	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FNA65_RS03355	COG0702	epimerase
FNA65_RS03360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNA65_RS03365	COG3023	N-Acetylmuramoyl-L-alanine amidase
FNA65_RS03380	COG1126	abc transporter atp-binding protein
FNA65_RS03385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA65_RS03390	COG4215	(ABC) transporter
FNA65_RS03395	COG4160	amino acid transport
FNA65_RS03400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA65_RS03415	COG1177	transmembrane transport
FNA65_RS03420	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNA65_RS03425	COG3842	ATPase activity
FNA65_RS03430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNA65_RS03445	COG0778	Nitroreductase
FNA65_RS03455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FNA65_RS03525	COG3226	Transcriptional regulator
FNA65_RS03530	COG0738	Major facilitator superfamily
FNA65_RS03535	COG0561	phosphatase activity
FNA65_RS03550	COG0671	phosphoesterase, PA-phosphatase related
FNA65_RS03555	COG1349	DNA-binding transcription factor activity
FNA65_RS03560	COG1686	Belongs to the peptidase S11 family
FNA65_RS03565	COG0625	glutathione transferase activity
FNA65_RS03570	COG2133	pyrroloquinoline quinone binding
FNA65_RS03585	COG2199	diguanylate cyclase activity
FNA65_RS03590	COG2200	EAL domain
FNA65_RS03615	COG0747	negative chemotaxis
FNA65_RS03625	COG1446	asparaginase
FNA65_RS03630	COG0303	'Molybdopterin
FNA65_RS03635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNA65_RS03640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNA65_RS03645	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNA65_RS03650	COG1882	Formate acetyltransferase
FNA65_RS03655	COG0561	phosphatase activity
FNA65_RS03665	COG0488	(ABC) transporter
FNA65_RS03670	COG1376	ErfK ybiS ycfS ynhG family protein
FNA65_RS03675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNA65_RS03680	COG1321	iron dependent repressor
FNA65_RS03690	COG2194	sulfuric ester hydrolase activity
FNA65_RS03695	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FNA65_RS03705	COG5006	permease, DMT superfamily
FNA65_RS03715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA65_RS03720	COG0765	amino acid transport
FNA65_RS03725	COG1126	abc transporter atp-binding protein
FNA65_RS03730	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS03735	COG0668	transmembrane transport
FNA65_RS03750	COG4774	siderophore transport
FNA65_RS03760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FNA65_RS03775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNA65_RS03780	COG1199	ATP-dependent helicase activity
FNA65_RS03790	COG0513	Belongs to the DEAD box helicase family
FNA65_RS03795	COG1309	transcriptional regulator
FNA65_RS03805	COG1131	(ABC) transporter
FNA65_RS03810	COG0842	Transport permease protein
FNA65_RS03815	COG0842	Transport permease protein
FNA65_RS03825	COG3568	Endonuclease Exonuclease Phosphatase
FNA65_RS03830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNA65_RS03835	COG0392	lysyltransferase activity
FNA65_RS03840	COG0670	Belongs to the BI1 family
FNA65_RS03845	COG0670	Belongs to the BI1 family
FNA65_RS03850	COG0314	molybdopterin synthase activity
FNA65_RS03855	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FNA65_RS03865	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNA65_RS03875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNA65_RS03885	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNA65_RS03890	COG2226	methyltransferase
FNA65_RS03905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNA65_RS03910	COG1881	PFAM PEBP family protein
FNA65_RS03915	COG4677	pectinesterase activity
FNA65_RS03920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FNA65_RS03945	COG2828	Protein conserved in bacteria
FNA65_RS03950	COG0583	DNA-binding transcription factor activity
FNA65_RS03960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FNA65_RS04015	COG4372	Transposase
FNA65_RS04020	COG4372	Transposase
FNA65_RS04025	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS04050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNA65_RS04065	COG3468	outer membrane autotransporter barrel domain protein
FNA65_RS04080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNA65_RS04085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNA65_RS04090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNA65_RS04100	COG4372	Transposase
FNA65_RS04105	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS04120	COG0584	glycerophosphoryl diester phosphodiesterase
FNA65_RS04125	COG2271	Major facilitator Superfamily
FNA65_RS04130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNA65_RS04140	COG0247	lactate metabolic process
FNA65_RS04145	COG5464	transposase or invertase
FNA65_RS04185	COG4372	Transposase
FNA65_RS04190	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS04200	COG0318	PFAM AMP-dependent synthetase and ligase
FNA65_RS04210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FNA65_RS04225	COG1169	isochorismate synthase
FNA65_RS04230	COG4575	ribosome binding
FNA65_RS04235	COG2153	protein acetylation
FNA65_RS04270	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNA65_RS04275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNA65_RS04285	COG0839	Belongs to the complex I subunit 6 family
FNA65_RS04300	COG1034	ATP synthesis coupled electron transport
FNA65_RS04305	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNA65_RS04310	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FNA65_RS04330	COG0583	DNA-binding transcription factor activity
FNA65_RS04335	COG0436	Aminotransferase
FNA65_RS04345	COG0471	metal ion transport
FNA65_RS04345	COG0490	domain, Protein
FNA65_RS04350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNA65_RS04365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNA65_RS04370	COG0857	belongs to the CobB CobQ family
FNA65_RS04370	COG0280	phosphate acetyltransferase
FNA65_RS04375	COG1288	antiporter activity
FNA65_RS04380	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNA65_RS04385	COG0622	Phosphoesterase
FNA65_RS04390	COG0625	glutathione transferase activity
FNA65_RS04400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNA65_RS04405	COG1090	epimerase
FNA65_RS04425	COG4598	ABC transporter
FNA65_RS04430	COG4160	amino acid transport
FNA65_RS04435	COG4215	(ABC) transporter
FNA65_RS04440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA65_RS04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA65_RS04450	COG0163	prenyltransferase activity
FNA65_RS04455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FNA65_RS04460	COG1286	toxin biosynthetic process
FNA65_RS04465	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FNA65_RS04470	COG0285	dihydrofolate synthase activity
FNA65_RS04480	COG0586	Pfam SNARE associated Golgi protein
FNA65_RS04490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNA65_RS04505	COG2814	Major facilitator Superfamily
FNA65_RS04510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNA65_RS04525	COG3101	peptidyl-lysine hydroxylation
FNA65_RS04530	COG0730	response to heat
FNA65_RS04545	COG2890	protein-(glutamine-N5) methyltransferase activity
FNA65_RS04570	COG4372	Transposase
FNA65_RS04575	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS04595	COG3539	Fimbrial protein
FNA65_RS04600	COG3539	Fimbrial protein
FNA65_RS04605	COG3121	Chaperone
FNA65_RS04610	COG3188	usher protein
FNA65_RS04615	COG3539	Fimbrial protein
FNA65_RS04620	COG3539	Fimbrial protein
FNA65_RS04625	COG2062	phosphohistidine phosphatase, SixA
FNA65_RS04640	COG3691	Protein conserved in bacteria
FNA65_RS04645	COG2067	long-chain fatty acid transport protein
FNA65_RS04650	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS04665	COG2853	Lipoprotein
FNA65_RS04670	COG2116	formate transmembrane transporter activity
FNA65_RS04695	COG0477	Major facilitator Superfamily
FNA65_RS04700	COG1566	PFAM secretion protein HlyD family protein
FNA65_RS04705	COG2197	response regulator
FNA65_RS04710	COG2205	protein histidine kinase activity
FNA65_RS04710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA65_RS04710	COG2198	Histidine kinase
FNA65_RS04710	COG0784	Response regulator, receiver
FNA65_RS04715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNA65_RS04720	COG0679	Auxin Efflux Carrier
FNA65_RS04725	COG0028	Belongs to the TPP enzyme family
FNA65_RS04750	COG1560	Kdo2-lipid A biosynthetic process
FNA65_RS04760	COG0436	Aminotransferase
FNA65_RS04765	COG3275	phosphorelay sensor kinase activity
FNA65_RS04770	COG3279	Response regulator of the LytR AlgR family
FNA65_RS04775	COG2207	Transcriptional regulator
FNA65_RS04790	COG0006	proline dipeptidase activity
FNA65_RS04795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNA65_RS04800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNA65_RS04825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNA65_RS04830	COG3385	transposase activity
FNA65_RS04870	COG3415	Transposase
FNA65_RS04875	COG3415	Transposase
FNA65_RS04910	COG0583	DNA-binding transcription factor activity
FNA65_RS04915	COG0385	Bile acid
FNA65_RS04920	COG3530	Putative quorum-sensing-regulated virulence factor
FNA65_RS04940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNA65_RS04945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS04950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNA65_RS04955	COG2190	(PTS) system
FNA65_RS04960	COG3385	transposase activity
FNA65_RS04975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNA65_RS04980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FNA65_RS04985	COG4208	sulfate ABC transporter
FNA65_RS04990	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FNA65_RS04995	COG4150	thiosulfate binding
FNA65_RS05000	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS05025	COG2837	iron assimilation
FNA65_RS05045	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNA65_RS05055	COG2207	Transcriptional regulator
FNA65_RS05060	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FNA65_RS05065	COG4816	utilization protein
FNA65_RS05080	COG4303	Ethanolamine ammonia lyase large subunit
FNA65_RS05085	COG4819	ethanolamine utilization protein
FNA65_RS05090	COG3192	ethanolamine utilization protein
FNA65_RS05095	COG1454	alcohol dehydrogenase
FNA65_RS05100	COG4820	ethanolamine utilization protein (EutJ)
FNA65_RS05105	COG1012	belongs to the aldehyde dehydrogenase family
FNA65_RS05110	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FNA65_RS05115	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FNA65_RS05120	COG0280	phosphate acetyltransferase
FNA65_RS05125	COG4812	Cobalamin adenosyltransferase
FNA65_RS05130	COG4766	ethanolamine catabolic process
FNA65_RS05135	COG4917	ethanolamine utilization protein
FNA65_RS05140	COG4810	utilization protein
FNA65_RS05145	COG0280	phosphate acetyltransferase
FNA65_RS05145	COG0281	malic enzyme
FNA65_RS05150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNA65_RS05155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FNA65_RS05160	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS05170	COG5342	invasion associated locus B
FNA65_RS05185	COG3850	Histidine kinase
FNA65_RS05205	COG1393	Belongs to the ArsC family
FNA65_RS05220	COG0400	carboxylic ester hydrolase activity
FNA65_RS05230	COG2321	neutral zinc metallopeptidase
FNA65_RS05240	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FNA65_RS05250	COG2716	regulation of RNA biosynthetic process
FNA65_RS05255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FNA65_RS05260	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNA65_RS05270	COG0650	Formate hydrogenlyase subunit 4
FNA65_RS05275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNA65_RS05285	COG4237	Hydrogenase 4 membrane
FNA65_RS05290	COG0651	ATP synthesis coupled electron transport
FNA65_RS05295	COG3261	NADH dehydrogenase
FNA65_RS05295	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FNA65_RS05300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNA65_RS05305	COG3260	NADH ubiquinone oxidoreductase 20
FNA65_RS05320	COG2116	formate transmembrane transporter activity
FNA65_RS05325	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS05330	COG2116	formate transmembrane transporter activity
FNA65_RS05335	COG0628	permease
FNA65_RS05340	COG4783	chaperone-mediated protein folding
FNA65_RS05345	COG1393	Belongs to the ArsC family
FNA65_RS05355	COG2233	PERMEase
FNA65_RS05370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FNA65_RS05375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FNA65_RS05380	COG0248	Ppx GppA phosphatase
FNA65_RS05410	COG0517	IMP dehydrogenase activity
FNA65_RS05410	COG0516	GMP reductase activity
FNA65_RS05420	COG1645	bacterial-type flagellum-dependent swarming motility
FNA65_RS05435	COG2976	Protein conserved in bacteria
FNA65_RS05470	COG2373	Large extracellular alpha-helical protein
FNA65_RS05490	COG2975	iron-sulfur cluster assembly
FNA65_RS05495	COG0633	Ferredoxin
FNA65_RS05515	COG0822	iron-sulfur transferase activity
FNA65_RS05535	COG0483	inositol monophosphate 1-phosphatase activity
FNA65_RS05540	COG1073	alpha beta
FNA65_RS05545	COG3711	transcriptional antiterminator
FNA65_RS05550	COG2814	Major facilitator Superfamily
FNA65_RS05555	COG0583	DNA-binding transcription factor activity
FNA65_RS05565	COG1940	carbohydrate kinase activity
FNA65_RS05575	COG1017	nitric oxide dioxygenase activity
FNA65_RS05575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNA65_RS05580	COG0347	Belongs to the P(II) protein family
FNA65_RS05585	COG2204	response regulator
FNA65_RS05590	COG3170	Tfp pilus assembly protein FimV
FNA65_RS05595	COG2205	protein histidine kinase activity
FNA65_RS05615	COG0560	Phosphoserine phosphatase
FNA65_RS05620	COG1737	Transcriptional regulator
FNA65_RS05625	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNA65_RS05660	COG0681	Belongs to the peptidase S26 family
FNA65_RS05670	COG3086	response to oxidative stress
FNA65_RS05675	COG3026	antisigma factor binding
FNA65_RS05680	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FNA65_RS05685	COG1595	DNA-templated transcription, initiation
FNA65_RS05695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNA65_RS05720	COG0513	Belongs to the DEAD box helicase family
FNA65_RS05740	COG4372	Transposase
FNA65_RS05745	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS05760	COG5544	Lipoprotein
FNA65_RS05765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNA65_RS05770	COG0045	succinate-CoA ligase (ADP-forming) activity
FNA65_RS05770	COG1042	CoA-binding domain protein
FNA65_RS05770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNA65_RS05775	COG3148	PFAM DTW domain containing protein
FNA65_RS05780	COG3118	belongs to the thioredoxin family
FNA65_RS05785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNA65_RS05815	COG4372	Transposase
FNA65_RS05820	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS05835	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS05840	COG4372	Transposase
FNA65_RS05870	COG0542	response to heat
FNA65_RS05880	COG0564	pseudouridine synthase activity
FNA65_RS05885	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNA65_RS05905	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNA65_RS05915	COG0077	Prephenate dehydratase
FNA65_RS05915	COG1605	Chorismate mutase
FNA65_RS05920	COG0287	Prephenate dehydrogenase
FNA65_RS05920	COG1605	Chorismate mutase
FNA65_RS05925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FNA65_RS05980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FNA65_RS05985	COG4137	Cytochrome C assembly protein
FNA65_RS05990	COG4536	flavin adenine dinucleotide binding
FNA65_RS06005	COG0497	DNA recombination
FNA65_RS06010	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNA65_RS06020	COG2867	negative regulation of translational initiation
FNA65_RS06045	COG0814	amino acid
FNA65_RS06050	COG0183	Belongs to the thiolase family
FNA65_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS06070	COG2814	Major facilitator Superfamily
FNA65_RS06075	COG1794	racemase activity, acting on amino acids and derivatives
FNA65_RS06080	COG0583	DNA-binding transcription factor activity
FNA65_RS06090	COG1609	Transcriptional regulator
FNA65_RS06110	COG0667	Aldo Keto reductase
FNA65_RS06120	COG0861	Integral membrane protein TerC family
FNA65_RS06140	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FNA65_RS06155	COG2165	general secretion pathway protein
FNA65_RS06160	COG4795	General secretion pathway protein
FNA65_RS06170	COG4967	type IV pilus modification protein PilV
FNA65_RS06175	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FNA65_RS06180	COG1025	Belongs to the peptidase M16 family
FNA65_RS06185	COG1074	ATP-dependent DNA helicase activity
FNA65_RS06190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNA65_RS06195	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FNA65_RS06195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNA65_RS06200	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNA65_RS06210	COG1263	PTS System
FNA65_RS06210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNA65_RS06250	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FNA65_RS06255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FNA65_RS06260	COG2166	iron-sulfur cluster assembly
FNA65_RS06265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNA65_RS06275	COG0583	DNA-binding transcription factor activity
FNA65_RS06280	COG2363	Small membrane protein
FNA65_RS06330	COG1760	l-serine dehydratase
FNA65_RS06335	COG0814	amino acid
FNA65_RS06340	COG1611	Belongs to the LOG family
FNA65_RS06355	COG3098	single-species biofilm formation
FNA65_RS06360	COG0564	pseudouridine synthase activity
FNA65_RS06365	COG0716	FMN binding
FNA65_RS06370	COG2271	Major facilitator Superfamily
FNA65_RS06380	COG4948	Mandelate Racemase Muconate Lactonizing
FNA65_RS06385	COG4999	Histidine kinase
FNA65_RS06385	COG3850	Histidine kinase
FNA65_RS06385	COG3437	response regulator, receiver
FNA65_RS06385	COG2205	protein histidine kinase activity
FNA65_RS06395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNA65_RS06400	COG2336	PFAM SpoVT AbrB
FNA65_RS06405	COG2337	Toxic component of a toxin-antitoxin (TA) module
FNA65_RS06410	COG3956	TIGRFAM MazG family protein
FNA65_RS06435	COG0602	queuosine metabolic process
FNA65_RS06445	COG0477	Major facilitator Superfamily
FNA65_RS06450	COG2086	electron transfer activity
FNA65_RS06455	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FNA65_RS06460	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FNA65_RS06465	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FNA65_RS06470	COG0644	oxidoreductase
FNA65_RS06475	COG0720	synthase
FNA65_RS06530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNA65_RS06535	COG2234	aminopeptidase activity
FNA65_RS06590	COG1388	LysM domain
FNA65_RS06590	COG4942	peptidase
FNA65_RS06600	COG2610	gluconate transmembrane transporter activity
FNA65_RS06605	COG3622	Belongs to the hyi family
FNA65_RS06610	COG0235	Class ii aldolase
FNA65_RS06620	COG2084	Dehydrogenase
FNA65_RS06625	COG1349	DNA-binding transcription factor activity
FNA65_RS06655	COG0309	Hydrogenase expression formation protein (HypE)
FNA65_RS06660	COG0409	Hydrogenase expression formation protein
FNA65_RS06665	COG0298	carbon dioxide binding
FNA65_RS06670	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNA65_RS06675	COG0375	protein maturation
FNA65_RS06690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNA65_RS06700	COG0650	Formate hydrogenlyase subunit 4
FNA65_RS06710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNA65_RS06725	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FNA65_RS06730	COG2723	6-phospho-beta-galactosidase activity
FNA65_RS06735	COG1263	PTS System
FNA65_RS06735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNA65_RS06740	COG1609	Transcriptional regulator
FNA65_RS06745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNA65_RS06750	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FNA65_RS06775	COG1349	DNA-binding transcription factor activity
FNA65_RS06780	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS06795	COG3732	PTS system glucitol sorbitol-specific
FNA65_RS06800	COG3730	PTS system glucitol sorbitol-specific
FNA65_RS06805	COG2951	lytic endotransglycosylase activity
FNA65_RS06810	COG1546	Belongs to the CinA family
FNA65_RS06830	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FNA65_RS06855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNA65_RS06860	COG1238	metal cluster binding
FNA65_RS06875	COG2814	Major facilitator Superfamily
FNA65_RS06880	COG1566	PFAM secretion protein HlyD family protein
FNA65_RS06885	COG1846	Transcriptional regulator
FNA65_RS06895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FNA65_RS06900	COG2814	Major facilitator Superfamily
FNA65_RS06920	COG2113	Glycine betaine
FNA65_RS06925	COG4176	ABC-type proline glycine betaine transport system permease component
FNA65_RS06930	COG4175	Glycine betaine
FNA65_RS06935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNA65_RS06940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNA65_RS06950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FNA65_RS06955	COG4575	ribosome binding
FNA65_RS06975	COG2916	Histone family protein nucleoid-structuring protein H-NS
FNA65_RS06980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNA65_RS06985	COG0640	Transcriptional regulator
FNA65_RS06990	COG0401	homolog of Blt101
FNA65_RS06995	COG1652	LysM domain
FNA65_RS07000	COG1802	Transcriptional regulator
FNA65_RS07005	COG1113	amino acid transport
FNA65_RS07020	COG0579	oxidoreductase
FNA65_RS07030	COG0366	Alpha amylase catalytic
FNA65_RS07065	COG2271	Major facilitator Superfamily
FNA65_RS07080	COG2084	Dehydrogenase
FNA65_RS07085	COG1929	Belongs to the glycerate kinase type-1 family
FNA65_RS07125	COG0583	DNA-binding transcription factor activity
FNA65_RS07130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNA65_RS07140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNA65_RS07145	COG1882	Formate acetyltransferase
FNA65_RS07150	COG0251	oxidation-reduction process
FNA65_RS07155	COG1760	l-serine dehydratase
FNA65_RS07165	COG0814	amino acid
FNA65_RS07180	COG1741	Belongs to the pirin family
FNA65_RS07200	COG3152	Membrane
FNA65_RS07210	COG4372	Transposase
FNA65_RS07215	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS07225	COG3152	Membrane
FNA65_RS07230	COG0435	Glutathione S-transferase
FNA65_RS07235	COG2259	Doxx family
FNA65_RS07245	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FNA65_RS07250	COG4575	ribosome binding
FNA65_RS07255	COG1422	Protein of unknown function (DUF1090)
FNA65_RS07265	COG0586	Pfam SNARE associated Golgi protein
FNA65_RS07270	COG2186	Transcriptional regulator
FNA65_RS07300	COG0583	DNA-binding transcription factor activity
FNA65_RS07305	COG0312	modulator of DNA gyrase
FNA65_RS07310	COG3164	Protein of unknown function
FNA65_RS07315	COG1530	ribonuclease E activity
FNA65_RS07325	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FNA65_RS07330	COG1792	Involved in formation and maintenance of cell shape
FNA65_RS07335	COG1077	Cell shape determining protein MreB Mrl
FNA65_RS07340	COG2199	diguanylate cyclase activity
FNA65_RS07340	COG2200	EAL domain
FNA65_RS07345	COG0604	alcohol dehydrogenase
FNA65_RS07350	COG0511	ligase activity, forming carbon-carbon bonds
FNA65_RS07355	COG0439	Biotin carboxylase
FNA65_RS07365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA65_RS07440	COG4974	Belongs to the 'phage' integrase family
FNA65_RS07450	COG4942	peptidase
FNA65_RS07485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FNA65_RS07490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FNA65_RS07495	COG4974	Belongs to the 'phage' integrase family
FNA65_RS07500	COG0716	FMN binding
FNA65_RS07510	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FNA65_RS07520	COG1272	protein, Hemolysin III
FNA65_RS07530	COG2723	6-phospho-beta-galactosidase activity
FNA65_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS07560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNA65_RS07565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNA65_RS07570	COG0006	proline dipeptidase activity
FNA65_RS07590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNA65_RS07605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNA65_RS07635	COG1703	isobutyryl-CoA mutase activity
FNA65_RS07640	COG1024	Enoyl-CoA hydratase
FNA65_RS07660	COG0583	DNA-binding transcription factor activity
FNA65_RS07665	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS07670	COG2968	Membrane
FNA65_RS07680	COG0668	transmembrane transport
FNA65_RS07685	COG0191	fructose-bisphosphate aldolase activity
FNA65_RS07715	COG1122	ATPase activity
FNA65_RS07720	COG1122	ATPase activity
FNA65_RS07725	COG1072	(Pantothenic acid kinase))
FNA65_RS07730	COG3722	fumarate hydratase activity
FNA65_RS07735	COG1494	fructose-1,6-bisphosphatase
FNA65_RS07740	COG1063	alcohol dehydrogenase
FNA65_RS07750	COG1063	alcohol dehydrogenase
FNA65_RS07755	COG2213	PTS system mannitol-specific
FNA65_RS07760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS07765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FNA65_RS07770	COG0501	Belongs to the peptidase M48B family
FNA65_RS07780	COG1166	arginine decarboxylase activity
FNA65_RS07795	COG2814	Major facilitator Superfamily
FNA65_RS07805	COG2356	endonuclease I
FNA65_RS07810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FNA65_RS07815	COG0189	ligase activity
FNA65_RS07830	COG2805	Type II/IV secretion system protein
FNA65_RS07835	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FNA65_RS07840	COG0762	integral membrane protein
FNA65_RS07855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNA65_RS07865	COG0252	asparaginase activity
FNA65_RS07875	COG3171	Protein conserved in bacteria
FNA65_RS07885	COG1194	a g-specific adenine glycosylase
FNA65_RS07900	COG2211	Major facilitator Superfamily
FNA65_RS07915	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS07925	COG1811	Na channel or pump
FNA65_RS07935	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FNA65_RS07965	COG2165	general secretion pathway protein
FNA65_RS07970	COG1459	type II secretion system
FNA65_RS07995	COG4372	Transposase
FNA65_RS08000	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS08015	COG4238	major outer membrane lipoprotein
FNA65_RS08025	COG0656	L-ascorbic acid biosynthetic process
FNA65_RS08035	COG4372	Transposase
FNA65_RS08040	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS08050	COG1979	alcohol dehydrogenase
FNA65_RS08055	COG2207	Transcriptional regulator
FNA65_RS08060	COG0586	Pfam SNARE associated Golgi protein
FNA65_RS08065	COG0626	cystathionine gamma-synthase activity
FNA65_RS08070	COG0811	peptide transport
FNA65_RS08075	COG0848	biopolymer transport protein
FNA65_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS08090	COG0667	Aldo Keto reductase
FNA65_RS08115	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FNA65_RS08120	COG0437	4 iron, 4 sulfur cluster binding
FNA65_RS08125	COG5557	Pfam Polysulphide reductase, NrfD
FNA65_RS08130	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FNA65_RS08135	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FNA65_RS08140	COG1773	rubredoxin
FNA65_RS08150	COG0298	carbon dioxide binding
FNA65_RS08155	COG0625	glutathione transferase activity
FNA65_RS08160	COG0754	glutathionylspermidine amidase activity
FNA65_RS08175	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS08180	COG4372	Transposase
FNA65_RS08190	COG1032	radical SAM domain protein
FNA65_RS08200	COG2132	Multicopper oxidase
FNA65_RS08205	COG0204	Acyl-transferase
FNA65_RS08210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNA65_RS08215	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FNA65_RS08220	COG3111	PFAM Bacterial OB fold (BOF) protein
FNA65_RS08225	COG0745	RESPONSE REGULATOR receiver
FNA65_RS08230	COG0642	Histidine kinase
FNA65_RS08235	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNA65_RS08240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FNA65_RS08245	COG0187	DNA topoisomerase II activity
FNA65_RS08250	COG3150	esterase
FNA65_RS08255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNA65_RS08260	COG3151	Protein conserved in bacteria
FNA65_RS08265	COG0494	nUDIX hydrolase
FNA65_RS08270	COG1538	Outer membrane efflux protein
FNA65_RS08280	COG0754	glutathionylspermidine amidase activity
FNA65_RS08285	COG3384	dioxygenase
FNA65_RS08305	COG2960	long-chain fatty acid transporting porin activity
FNA65_RS08310	COG3539	Fimbrial protein
FNA65_RS08345	COG3025	triphosphatase activity
FNA65_RS08365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNA65_RS08385	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FNA65_RS08395	COG0471	metal ion transport
FNA65_RS08405	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FNA65_RS08410	COG0358	DNA primase activity
FNA65_RS08415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNA65_RS08420	COG3385	transposase activity
FNA65_RS08435	COG2375	cellular response to nickel ion
FNA65_RS08440	COG1695	Transcriptional regulator
FNA65_RS08445	COG0840	transmembrane signaling receptor activity
FNA65_RS08475	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FNA65_RS08475	COG3408	Glycogen debranching enzyme
FNA65_RS08490	COG5499	transcription regulator containing HTH domain
FNA65_RS08495	COG4680	protein conserved in bacteria
FNA65_RS08505	COG1451	nucleotide metabolic process
FNA65_RS08510	COG2949	membrane
FNA65_RS08515	COG0673	inositol 2-dehydrogenase activity
FNA65_RS08520	COG0861	Integral membrane protein TerC family
FNA65_RS08535	COG2721	sulfolactate sulfo-lyase activity
FNA65_RS08545	COG2271	Major facilitator Superfamily
FNA65_RS08575	COG2732	(Barnase) inhibitor
FNA65_RS08595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNA65_RS08600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNA65_RS08605	COG3105	Protein conserved in bacteria
FNA65_RS08610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FNA65_RS08625	COG0625	glutathione transferase activity
FNA65_RS08630	COG2969	positive regulation of protein catabolic process
FNA65_RS08665	COG2731	YhcH YjgK YiaL family protein
FNA65_RS08675	COG4804	nuclease activity
FNA65_RS08680	COG0493	'glutamate synthase
FNA65_RS08685	COG0070	glutamate synthase
FNA65_RS08685	COG0069	glutamate synthase activity
FNA65_RS08685	COG0067	glutamate synthase
FNA65_RS08690	COG1242	4 iron, 4 sulfur cluster binding
FNA65_RS08695	COG2198	Histidine kinase
FNA65_RS08695	COG5002	protein histidine kinase activity
FNA65_RS08695	COG0784	Response regulator, receiver
FNA65_RS08700	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FNA65_RS08710	COG0515	serine threonine protein kinase
FNA65_RS08715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS08730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNA65_RS08735	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FNA65_RS08740	COG1137	ATPase activity
FNA65_RS08745	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FNA65_RS08750	COG3117	lipopolysaccharide transmembrane transporter activity
FNA65_RS08755	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FNA65_RS08760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNA65_RS08760	COG0517	IMP dehydrogenase activity
FNA65_RS08765	COG0530	calcium, potassium:sodium antiporter activity
FNA65_RS08770	COG1127	ABC transporter
FNA65_RS08775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNA65_RS08780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FNA65_RS08785	COG2854	intermembrane phospholipid transfer
FNA65_RS08790	COG3113	response to antibiotic
FNA65_RS08795	COG5007	Belongs to the BolA IbaG family
FNA65_RS08805	COG3423	Transcriptional regulator
FNA65_RS08810	COG0142	geranyltranstransferase activity
FNA65_RS08825	COG0697	spore germination
FNA65_RS08835	COG2027	D-alanyl-D-alanine carboxypeptidase
FNA65_RS08840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNA65_RS08845	COG1534	Rna-binding protein
FNA65_RS08855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNA65_RS08860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNA65_RS08870	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNA65_RS08880	COG2194	sulfuric ester hydrolase activity
FNA65_RS08920	COG0195	Participates in both transcription termination and antitermination
FNA65_RS08960	COG0513	Belongs to the DEAD box helicase family
FNA65_RS08965	COG0814	amino acid
FNA65_RS08970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNA65_RS08975	COG0826	peptidase U32
FNA65_RS08980	COG0826	peptidase U32
FNA65_RS08985	COG3154	lipid carrier protein
FNA65_RS08990	COG3153	acetyltransferase
FNA65_RS09005	COG0693	protein deglycase activity
FNA65_RS09010	COG0702	epimerase
FNA65_RS09015	COG0701	Predicted permease
FNA65_RS09020	COG2823	Periplasmic or secreted lipoprotein
FNA65_RS09040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FNA65_RS09090	COG1349	DNA-binding transcription factor activity
FNA65_RS09095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA65_RS09100	COG3924	membrane
FNA65_RS09105	COG4145	pantothenate transmembrane transporter activity
FNA65_RS09115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNA65_RS09125	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FNA65_RS09135	COG1309	transcriptional regulator
FNA65_RS09140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNA65_RS09155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA65_RS09195	COG0765	amino acid transport
FNA65_RS09200	COG1126	abc transporter atp-binding protein
FNA65_RS09245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FNA65_RS09265	COG0551	DNA topoisomerase type I activity
FNA65_RS09275	COG0758	DNA mediated transformation
FNA65_RS09295	COG0569	domain protein
FNA65_RS09305	COG3036	rescue of stalled ribosome
FNA65_RS09310	COG0789	Transcriptional regulator
FNA65_RS09350	COG0201	protein transport
FNA65_RS09440	COG0089	rRNA binding
FNA65_RS09475	COG4372	Transposase
FNA65_RS09480	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS09545	COG2964	Protein conserved in bacteria
FNA65_RS09550	COG0545	Peptidyl-prolyl cis-trans isomerase
FNA65_RS09560	COG1047	Peptidyl-prolyl cis-trans
FNA65_RS09565	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FNA65_RS09580	COG0488	(ABC) transporter
FNA65_RS09585	COG0429	hydrolase of the alpha beta-hydrolase fold
FNA65_RS09595	COG3954	Phosphoribulokinase
FNA65_RS09600	COG1765	OsmC-like protein
FNA65_RS09610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNA65_RS09615	COG1289	transmembrane transporter activity
FNA65_RS09625	COG0512	Glutamine amidotransferase of anthranilate synthase
FNA65_RS09630	COG2184	nucleotidyltransferase activity
FNA65_RS09640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNA65_RS09655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNA65_RS09660	COG2146	nitrite reductase [NAD(P)H] activity
FNA65_RS09665	COG2116	formate transmembrane transporter activity
FNA65_RS09685	COG0531	amino acid
FNA65_RS09695	COG1082	Xylose isomerase domain protein TIM barrel
FNA65_RS09700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA65_RS09705	COG2188	Transcriptional regulator
FNA65_RS09710	COG0626	cystathionine gamma-synthase activity
FNA65_RS09720	COG3385	transposase activity
FNA65_RS09735	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FNA65_RS09740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FNA65_RS09745	COG3457	Alanine racemase
FNA65_RS09755	COG2188	Transcriptional regulator
FNA65_RS09760	COG0180	Tryptophanyl-tRNA synthetase
FNA65_RS09770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNA65_RS09775	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FNA65_RS09780	COG3266	domain, Protein
FNA65_RS09795	COG4796	Type ii and iii secretion system protein
FNA65_RS09810	COG3166	PFAM Fimbrial assembly family protein
FNA65_RS09815	COG4972	Pilus assembly protein
FNA65_RS09820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNA65_RS09825	COG0494	nUDIX hydrolase
FNA65_RS09835	COG1011	Hydrolase
FNA65_RS09840	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FNA65_RS09850	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FNA65_RS09870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNA65_RS09875	COG2183	response to ionizing radiation
FNA65_RS09885	COG1918	ferrous iron import across plasma membrane
FNA65_RS09890	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FNA65_RS09900	COG5464	transposase or invertase
FNA65_RS09910	COG1040	competence protein
FNA65_RS09920	COG2610	gluconate transmembrane transporter activity
FNA65_RS09925	COG1640	4-alpha-glucanotransferase
FNA65_RS09930	COG0058	SHG alpha-glucan phosphorylase activity
FNA65_RS09945	COG1690	Belongs to the RtcB family
FNA65_RS09955	COG4650	regulator
FNA65_RS09960	COG1349	DNA-binding transcription factor activity
FNA65_RS09975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNA65_RS10015	COG1393	Belongs to the ArsC family
FNA65_RS10020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNA65_RS10025	COG0640	Transcriptional regulator
FNA65_RS10035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNA65_RS10040	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FNA65_RS10045	COG0339	signal peptide processing
FNA65_RS10055	COG3104	oligopeptide transport
FNA65_RS10065	COG0589	response to stress
FNA65_RS10075	COG0306	phosphate transporter
FNA65_RS10080	COG2081	HI0933 family
FNA65_RS10100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNA65_RS10105	COG1129	ABC transporter
FNA65_RS10105	COG0842	Transport permease protein
FNA65_RS10110	COG0842	Transport permease protein
FNA65_RS10135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA65_RS10140	COG0601	transmembrane transport
FNA65_RS10145	COG0747	negative chemotaxis
FNA65_RS10155	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS10160	COG2091	lysine biosynthetic process via aminoadipic acid
FNA65_RS10165	COG0628	permease
FNA65_RS10180	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FNA65_RS10195	COG3714	YhhN family
FNA65_RS10205	COG3776	membrane
FNA65_RS10210	COG0742	ribosomal rna small subunit methyltransferase
FNA65_RS10215	COG0552	protein localization to endoplasmic reticulum
FNA65_RS10220	COG2884	Cell division ATP-binding protein ftsE
FNA65_RS10225	COG2177	Part of the ABC transporter FtsEX involved in
FNA65_RS10230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNA65_RS10235	COG0683	leucine binding
FNA65_RS10240	COG0456	acetyltransferase
FNA65_RS10245	COG0683	leucine binding
FNA65_RS10250	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNA65_RS10255	COG4177	L-phenylalanine transmembrane transporter activity
FNA65_RS10260	COG0411	ABC transporter
FNA65_RS10265	COG0410	ABC transporter
FNA65_RS10270	COG1653	transport
FNA65_RS10275	COG1175	transmembrane transport
FNA65_RS10290	COG0584	glycerophosphoryl diester phosphodiesterase
FNA65_RS10300	COG0405	Gamma-glutamyltransferase
FNA65_RS10335	COG3157	Type VI secretion system effector, Hcp
FNA65_RS10340	COG1247	-acetyltransferase
FNA65_RS10345	COG0673	inositol 2-dehydrogenase activity
FNA65_RS10350	COG1741	Belongs to the pirin family
FNA65_RS10355	COG1609	Transcriptional regulator
FNA65_RS10360	COG3265	gluconokinase activity
FNA65_RS10365	COG2610	gluconate transmembrane transporter activity
FNA65_RS10370	COG2095	MarC family integral membrane protein
FNA65_RS10375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNA65_RS10400	COG0058	SHG alpha-glucan phosphorylase activity
FNA65_RS10415	COG4372	Transposase
FNA65_RS10420	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS10430	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS10435	COG4372	Transposase
FNA65_RS10460	COG3065	identical protein binding
FNA65_RS10465	COG2197	response regulator
FNA65_RS10470	COG1285	pathogenesis
FNA65_RS10485	COG3247	response to pH
FNA65_RS10490	COG2771	luxR family
FNA65_RS10500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNA65_RS10505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNA65_RS10510	COG2207	Transcriptional regulator
FNA65_RS10535	COG1858	cytochrome C peroxidase
FNA65_RS10560	COG3385	transposase activity
FNA65_RS10565	COG2197	response regulator
FNA65_RS10570	COG0583	DNA-binding transcription factor activity
FNA65_RS10575	COG1295	ribonuclease BN
FNA65_RS10580	COG0477	Major facilitator Superfamily
FNA65_RS10595	COG2982	Protein involved in outer membrane biogenesis
FNA65_RS10600	COG2200	EAL domain
FNA65_RS10610	COG0612	Peptidase, M16
FNA65_RS10620	COG2200	EAL domain
FNA65_RS10620	COG2199	diguanylate cyclase activity
FNA65_RS10635	COG1215	transferase activity, transferring glycosyl groups
FNA65_RS10640	COG1215	transferase activity, transferring glycosyl groups
FNA65_RS10665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FNA65_RS10680	COG1414	Transcriptional regulator
FNA65_RS10685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNA65_RS10690	COG3977	Valine--pyruvate aminotransferase
FNA65_RS10695	COG0366	Alpha amylase catalytic
FNA65_RS10700	COG2992	FlgJ-related protein
FNA65_RS10705	COG2207	Transcriptional regulator
FNA65_RS10705	COG1609	Transcriptional regulator
FNA65_RS10710	COG4214	carbohydrate transport
FNA65_RS10720	COG4213	ABC transporter substrate-binding protein
FNA65_RS10735	COG1070	Carbohydrate kinase
FNA65_RS10740	COG1070	Carbohydrate kinase
FNA65_RS10780	COG1278	Cold shock
FNA65_RS10785	COG2944	sequence-specific DNA binding
FNA65_RS10800	COG2885	chlorophyll binding
FNA65_RS10805	COG0243	molybdopterin cofactor binding
FNA65_RS10810	COG0456	acetyltransferase
FNA65_RS10815	COG2818	Glycosylase
FNA65_RS10820	COG5571	outer membrane autotransporter
FNA65_RS10825	COG2223	nitrite transmembrane transporter activity
FNA65_RS10845	COG2194	sulfuric ester hydrolase activity
FNA65_RS10855	COG0747	negative chemotaxis
FNA65_RS10860	COG0747	negative chemotaxis
FNA65_RS10865	COG0601	transmembrane transport
FNA65_RS10870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA65_RS10875	COG0444	Belongs to the ABC transporter superfamily
FNA65_RS10880	COG4608	Belongs to the ABC transporter superfamily
FNA65_RS10885	COG0814	amino acid
FNA65_RS10910	COG3385	transposase activity
FNA65_RS10940	COG1012	belongs to the aldehyde dehydrogenase family
FNA65_RS10945	COG1454	alcohol dehydrogenase
FNA65_RS10950	COG3276	selenocysteine insertion sequence binding
FNA65_RS10960	COG0625	glutathione transferase activity
FNA65_RS10965	COG3209	COG3209 Rhs family protein
FNA65_RS10970	COG3209	COG3209 Rhs family protein
FNA65_RS10980	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FNA65_RS11005	COG1566	PFAM secretion protein HlyD family protein
FNA65_RS11015	COG2213	PTS system mannitol-specific
FNA65_RS11015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS11025	COG3722	fumarate hydratase activity
FNA65_RS11070	COG1620	l-lactate permease
FNA65_RS11075	COG2186	Transcriptional regulator
FNA65_RS11085	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS11090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FNA65_RS11095	COG1045	serine acetyltransferase
FNA65_RS11110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FNA65_RS11115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNA65_RS11125	COG4942	peptidase
FNA65_RS11130	COG2861	carbohydrate metabolic process
FNA65_RS11135	COG1216	Glycosyl transferase, family 2
FNA65_RS11145	COG0156	8-amino-7-oxononanoate synthase activity
FNA65_RS11155	COG0859	PFAM glycosyl transferase family 9
FNA65_RS11160	COG0859	PFAM glycosyl transferase family 9
FNA65_RS11165	COG3307	-O-antigen
FNA65_RS11170	COG1216	Glycosyl transferase, family 2
FNA65_RS11175	COG1442	glycosyl transferase family 8
FNA65_RS11180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FNA65_RS11195	COG0515	serine threonine protein kinase
FNA65_RS11200	COG0438	transferase activity, transferring glycosyl groups
FNA65_RS11205	COG0859	PFAM glycosyl transferase family 9
FNA65_RS11210	COG1519	Transferase
FNA65_RS11240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNA65_RS11265	COG1561	YicC-like family, N-terminal region
FNA65_RS11390	COG3645	SOS response
FNA65_RS11395	COG2860	membrane
FNA65_RS11405	COG0194	GDP metabolic process
FNA65_RS11415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNA65_RS11420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNA65_RS11425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FNA65_RS11430	COG0786	glutamate:sodium symporter activity
FNA65_RS11435	COG2233	PERMEase
FNA65_RS11440	COG2982	Protein involved in outer membrane biogenesis
FNA65_RS11445	COG1501	Belongs to the glycosyl hydrolase 31 family
FNA65_RS11450	COG2211	Major facilitator Superfamily
FNA65_RS11475	COG3385	transposase activity
FNA65_RS11485	COG0697	spore germination
FNA65_RS11490	COG1464	Belongs to the NlpA lipoprotein family
FNA65_RS11505	COG0641	radical SAM
FNA65_RS11530	COG1113	amino acid transport
FNA65_RS11550	COG2244	polysaccharide biosynthetic process
FNA65_RS11555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNA65_RS11560	COG0456	acetyltransferase
FNA65_RS11565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FNA65_RS11570	COG1088	dTDP-glucose 4,6-dehydratase activity
FNA65_RS11580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FNA65_RS11590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNA65_RS11595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FNA65_RS11605	COG3118	belongs to the thioredoxin family
FNA65_RS11620	COG0210	DNA helicase
FNA65_RS11630	COG3692	DNA binding
FNA65_RS11635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNA65_RS11645	COG0583	DNA-binding transcription factor activity
FNA65_RS11650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNA65_RS11660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNA65_RS11665	COG3978	acetolactate synthase activity
FNA65_RS11685	COG0606	chelatase, subunit chli
FNA65_RS11690	COG3085	chromosome segregation
FNA65_RS11730	COG2186	Transcriptional regulator
FNA65_RS11735	COG0477	Major facilitator Superfamily
FNA65_RS11740	COG1609	Transcriptional regulator
FNA65_RS11745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA65_RS11775	COG3385	transposase activity
FNA65_RS11795	COG1522	sequence-specific DNA binding
FNA65_RS11800	COG0716	FMN binding
FNA65_RS11815	COG3312	ion transport
FNA65_RS11895	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS11900	COG4372	Transposase
FNA65_RS11915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FNA65_RS11920	COG0573	inorganic phosphate transmembrane transporter activity
FNA65_RS11925	COG0581	inorganic phosphate transmembrane transporter activity
FNA65_RS11930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNA65_RS11935	COG0704	Plays a role in the regulation of phosphate uptake
FNA65_RS11950	COG2252	PERMEase
FNA65_RS11955	COG0431	NADPH-dependent FMN reductase
FNA65_RS11960	COG2091	lysine biosynthetic process via aminoadipic acid
FNA65_RS11975	COG0814	amino acid
FNA65_RS12040	COG0592	DNA-directed DNA polymerase activity
FNA65_RS12050	COG0187	DNA topoisomerase II activity
FNA65_RS12055	COG3753	Protein conserved in bacteria
FNA65_RS12070	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS12090	COG0823	Involved in the tonB-independent uptake of proteins
FNA65_RS12095	COG5645	(Lipo)protein
FNA65_RS12115	COG2188	Transcriptional regulator
FNA65_RS12140	COG0675	Transposase, IS605 OrfB family
FNA65_RS12150	COG2149	membrane
FNA65_RS12160	COG0641	radical SAM
FNA65_RS12165	COG2814	Major facilitator Superfamily
FNA65_RS12180	COG0028	Belongs to the TPP enzyme family
FNA65_RS12185	COG0440	acetolactate synthase activity
FNA65_RS12190	COG2197	response regulator
FNA65_RS12195	COG3851	Histidine kinase
FNA65_RS12200	COG2271	Major facilitator Superfamily
FNA65_RS12205	COG2271	Major facilitator Superfamily
FNA65_RS12215	COG2252	PERMEase
FNA65_RS12235	COG3071	HemY protein
FNA65_RS12240	COG2959	enzyme of heme biosynthesis
FNA65_RS12245	COG1587	Uroporphyrinogen-III synthase
FNA65_RS12255	COG3072	Adenylate cyclase
FNA65_RS12270	COG5567	small periplasmic lipoprotein
FNA65_RS12280	COG3159	Protein conserved in bacteria
FNA65_RS12290	COG1011	Hydrolase
FNA65_RS12295	COG0210	DNA helicase
FNA65_RS12300	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
FNA65_RS12310	COG3698	Phosphodiester glycosidase
FNA65_RS12315	COG0598	Magnesium transport protein CorA
FNA65_RS12330	COG2962	Rard protein
FNA65_RS12335	COG2050	protein possibly involved in aromatic compounds catabolism
FNA65_RS12340	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FNA65_RS12345	COG0514	ATP-dependent DNA helicase (RecQ)
FNA65_RS12350	COG1280	lysine exporter protein (LysE YggA)
FNA65_RS12355	COG1280	lysine exporter protein (LysE YggA)
FNA65_RS12360	COG2267	carboxylic ester hydrolase activity
FNA65_RS12365	COG0561	phosphatase activity
FNA65_RS12370	COG0697	spore germination
FNA65_RS12375	COG0583	DNA-binding transcription factor activity
FNA65_RS12415	COG0412	Dienelactone hydrolase
FNA65_RS12420	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FNA65_RS12425	COG1322	Protein conserved in bacteria
FNA65_RS12435	COG3165	ubiquinone biosynthetic process from chorismate
FNA65_RS12445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNA65_RS12450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNA65_RS12455	COG0805	protein transport
FNA65_RS12465	COG0250	Participates in transcription elongation, termination and antitermination
FNA65_RS12475	COG0543	2 iron, 2 sulfur cluster binding
FNA65_RS12495	COG1739	Uncharacterized protein family UPF0029
FNA65_RS12500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNA65_RS12505	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FNA65_RS12535	COG1763	Mo-molybdopterin cofactor biosynthetic process
FNA65_RS12540	COG0746	molybdenum cofactor guanylyltransferase activity
FNA65_RS12545	COG3084	Protein conserved in bacteria
FNA65_RS12555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FNA65_RS12560	COG5339	Protein conserved in bacteria
FNA65_RS12565	COG0204	Acyl-transferase
FNA65_RS12575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNA65_RS12575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNA65_RS12590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNA65_RS12600	COG2204	response regulator
FNA65_RS12605	COG3852	Histidine kinase
FNA65_RS12610	COG0174	glutamine synthetase
FNA65_RS12615	COG1217	gtp-binding protein TYPA
FNA65_RS12620	COG1349	DNA-binding transcription factor activity
FNA65_RS12625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA65_RS12635	COG3684	Belongs to the aldolase LacD family
FNA65_RS12640	COG1063	alcohol dehydrogenase
FNA65_RS12680	COG1011	Hydrolase
FNA65_RS12695	COG0456	acetyltransferase
FNA65_RS12710	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FNA65_RS12715	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FNA65_RS12725	COG2864	formate dehydrogenase
FNA65_RS12730	COG0437	4 iron, 4 sulfur cluster binding
FNA65_RS12795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNA65_RS12805	COG2258	MOSC domain
FNA65_RS12810	COG2205	protein histidine kinase activity
FNA65_RS12815	COG0745	RESPONSE REGULATOR receiver
FNA65_RS12820	COG3678	ATP-independent chaperone mediated protein folding
FNA65_RS12835	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FNA65_RS12855	COG3152	Membrane
FNA65_RS12865	COG3691	Protein conserved in bacteria
FNA65_RS12870	COG0589	response to stress
FNA65_RS12880	COG1494	fructose-1,6-bisphosphatase
FNA65_RS12890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNA65_RS12905	COG1575	Belongs to the MenA family. Type 1 subfamily
FNA65_RS12920	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FNA65_RS12925	COG1609	Transcriptional regulator
FNA65_RS12930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FNA65_RS12955	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FNA65_RS12965	COG0626	cystathionine gamma-synthase activity
FNA65_RS12970	COG0460	homoserine dehydrogenase
FNA65_RS12970	COG0527	aspartate kinase activity
FNA65_RS12980	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FNA65_RS12990	COG0697	spore germination
FNA65_RS12995	COG3738	Protein conserved in bacteria
FNA65_RS13000	COG0371	Dehydrogenase
FNA65_RS13005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNA65_RS13010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNA65_RS13010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS13010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS13020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNA65_RS13025	COG1882	Formate acetyltransferase
FNA65_RS13030	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNA65_RS13035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNA65_RS13045	COG2194	sulfuric ester hydrolase activity
FNA65_RS13060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FNA65_RS13075	COG0583	DNA-binding transcription factor activity
FNA65_RS13085	COG1309	transcriptional regulator
FNA65_RS13105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNA65_RS13135	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FNA65_RS13135	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FNA65_RS13170	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNA65_RS13175	COG0250	Participates in transcription elongation, termination and antitermination
FNA65_RS13220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNA65_RS13230	COG2104	thiamine diphosphate biosynthetic process
FNA65_RS13270	COG3068	Protein conserved in bacteria
FNA65_RS13285	COG3678	ATP-independent chaperone mediated protein folding
FNA65_RS13290	COG4191	Histidine kinase
FNA65_RS13295	COG2204	response regulator
FNA65_RS13300	COG0151	Belongs to the GarS family
FNA65_RS13340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNA65_RS13345	COG2224	Isocitrate lyase
FNA65_RS13370	COG1283	sodium-dependent phosphate transmembrane transporter activity
FNA65_RS13435	COG0527	aspartate kinase activity
FNA65_RS13460	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNA65_RS13485	COG1448	Aminotransferase
FNA65_RS13495	COG0305	Participates in initiation and elongation during chromosome replication
FNA65_RS13500	COG0604	alcohol dehydrogenase
FNA65_RS13510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNA65_RS13530	COG0735	belongs to the Fur family
FNA65_RS13535	COG3237	CsbD-like
FNA65_RS13540	COG0534	Mate efflux family protein
FNA65_RS13550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FNA65_RS13610	COG3700	Belongs to the class B bacterial acid phosphatase family
FNA65_RS13615	COG0432	Pfam Uncharacterised protein family UPF0047
FNA65_RS13620	COG2315	Protein conserved in bacteria
FNA65_RS13625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNA65_RS13630	COG0629	single-stranded DNA binding
FNA65_RS13640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FNA65_RS13655	COG2207	Transcriptional regulator
FNA65_RS13660	COG0789	Transcriptional regulator
FNA65_RS13665	COG2252	PERMEase
FNA65_RS13670	COG0025	NhaP-type Na H and K H
FNA65_RS13690	COG3162	membrane
FNA65_RS13715	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FNA65_RS13720	COG0437	4 iron, 4 sulfur cluster binding
FNA65_RS13725	COG3301	Polysulphide reductase, NrfD
FNA65_RS13730	COG1138	Cytochrome C-type biogenesis protein
FNA65_RS13735	COG3088	subunit of a heme lyase
FNA65_RS13740	COG4235	cytochrome complex assembly
FNA65_RS13745	COG1301	dicarboxylic acid transport
FNA65_RS13765	COG3624	Phosphonate C-P lyase system protein PhnG
FNA65_RS13770	COG2188	Transcriptional regulator
FNA65_RS13775	COG3639	organic phosphonate transmembrane transporter activity
FNA65_RS13780	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FNA65_RS13790	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FNA65_RS13795	COG2824	Alkylphosphonate utilization operon protein PhnA
FNA65_RS13810	COG0531	amino acid
FNA65_RS13815	COG2207	Transcriptional regulator
FNA65_RS13820	COG1982	Orn Lys Arg decarboxylase major
FNA65_RS13825	COG2169	Transcriptional regulator
FNA65_RS13830	COG1486	melibiose metabolic process
FNA65_RS13875	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS13880	COG4372	Transposase
FNA65_RS13900	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS13905	COG4372	Transposase
FNA65_RS13910	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS13925	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS13975	COG4372	Transposase
FNA65_RS13980	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS14035	COG3468	outer membrane autotransporter barrel domain protein
FNA65_RS14045	COG4372	Transposase
FNA65_RS14050	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS14100	COG4771	TonB-dependent receptor
FNA65_RS14130	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS14135	COG4372	Transposase
FNA65_RS14160	COG1309	transcriptional regulator
FNA65_RS14175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FNA65_RS14190	COG0531	amino acid
FNA65_RS14215	COG1509	lysine 2,3-aminomutase activity
FNA65_RS14225	COG5510	response to toxic substance
FNA65_RS14230	COG5510	response to toxic substance
FNA65_RS14235	COG2076	Multidrug Resistance protein
FNA65_RS14240	COG3040	lipid binding
FNA65_RS14245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNA65_RS14260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNA65_RS14265	COG1053	succinate dehydrogenase
FNA65_RS14290	COG1511	domain protein
FNA65_RS14290	COG3264	Mechanosensitive ion channel
FNA65_RS14330	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FNA65_RS14335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FNA65_RS14335	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FNA65_RS14340	COG0802	atpase or kinase
FNA65_RS14345	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNA65_RS14365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNA65_RS14370	COG0330	HflC and HflK could
FNA65_RS14375	COG0330	HflC and HflK could
FNA65_RS14380	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FNA65_RS14395	COG0557	exoribonuclease II activity
FNA65_RS14400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNA65_RS14410	COG3766	membrane
FNA65_RS14415	COG5463	Belongs to the UPF0441 family
FNA65_RS14420	COG0754	glutathionylspermidine amidase activity
FNA65_RS14425	COG1960	acyl-CoA dehydrogenase activity
FNA65_RS14435	COG3650	response to hydrogen peroxide
FNA65_RS14440	COG1073	alpha beta
FNA65_RS14455	COG3037	sugar-specific permease SgaT UlaA
FNA65_RS14485	COG3477	response to acidic pH
FNA65_RS14510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNA65_RS14530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNA65_RS14535	COG4670	ketone body catabolic process
FNA65_RS14540	COG1024	Enoyl-CoA hydratase
FNA65_RS14555	COG1309	transcriptional regulator
FNA65_RS14560	COG3061	Opacity-associated protein A
FNA65_RS14570	COG0545	Peptidyl-prolyl cis-trans isomerase
FNA65_RS14575	COG1113	amino acid transport
FNA65_RS14585	COG0697	spore germination
FNA65_RS14590	COG0702	epimerase
FNA65_RS14595	COG1733	regulation of RNA biosynthetic process
FNA65_RS14615	COG1218	3'(2'),5'-bisphosphate nucleotidase
FNA65_RS14655	COG2814	Major facilitator Superfamily
FNA65_RS14670	COG1924	4 iron, 4 sulfur cluster binding
FNA65_RS14695	COG3366	ferrous iron transmembrane transporter activity
FNA65_RS14705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FNA65_RS14710	COG0583	DNA-binding transcription factor activity
FNA65_RS14750	COG2186	Transcriptional regulator
FNA65_RS14755	COG0246	Mannitol dehydrogenase
FNA65_RS14770	COG3539	Fimbrial protein
FNA65_RS14775	COG3539	Fimbrial protein
FNA65_RS14780	COG3539	Fimbrial protein
FNA65_RS14805	COG3539	Fimbrial protein
FNA65_RS14815	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FNA65_RS14845	COG0582	viral genome integration into host DNA
FNA65_RS14855	COG1064	alcohol dehydrogenase
FNA65_RS14860	COG0433	COG0433 Predicted ATPase
FNA65_RS14865	COG0795	lipopolysaccharide-transporting ATPase activity
FNA65_RS14870	COG0795	lipopolysaccharide-transporting ATPase activity
FNA65_RS14880	COG2927	DNA polymerase III (CHI subunit)
FNA65_RS14900	COG4269	membrane
FNA65_RS14910	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FNA65_RS14935	COG2731	YhcH YjgK YiaL family protein
FNA65_RS14945	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS14950	COG0251	oxidation-reduction process
FNA65_RS14970	COG0251	oxidation-reduction process
FNA65_RS14975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNA65_RS14985	COG1609	Transcriptional regulator
FNA65_RS14990	COG1263	PTS System
FNA65_RS14990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNA65_RS14995	COG0366	Alpha amylase catalytic
FNA65_RS15000	COG1328	CTP reductase activity
FNA65_RS15005	COG0602	queuosine metabolic process
FNA65_RS15010	COG3783	Cytochrome b(562)
FNA65_RS15015	COG0312	modulator of DNA gyrase
FNA65_RS15025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNA65_RS15035	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA65_RS15040	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA65_RS15050	COG1879	ABC-type sugar transport system periplasmic component
FNA65_RS15055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FNA65_RS15060	COG2105	PFAM AIG2 family protein
FNA65_RS15065	COG2911	Protein conserved in bacteria
FNA65_RS15070	COG0729	surface antigen
FNA65_RS15080	COG1253	flavin adenine dinucleotide binding
FNA65_RS15090	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FNA65_RS15135	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS15145	COG0523	cobalamin synthesis protein
FNA65_RS15155	COG1966	Carbon starvation protein
FNA65_RS15160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNA65_RS15165	COG2368	4-hydroxyphenylacetate
FNA65_RS15185	COG3971	2-oxopent-4-enoate hydratase activity
FNA65_RS15195	COG3384	dioxygenase
FNA65_RS15200	COG1012	belongs to the aldehyde dehydrogenase family
FNA65_RS15205	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNA65_RS15210	COG1846	Transcriptional regulator
FNA65_RS15215	COG0840	transmembrane signaling receptor activity
FNA65_RS15240	COG1063	alcohol dehydrogenase
FNA65_RS15255	COG1484	DNA-dependent DNA replication
FNA65_RS15270	COG2966	Psort location CytoplasmicMembrane, score
FNA65_RS15280	COG2197	response regulator
FNA65_RS15320	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FNA65_RS15325	COG0456	acetyltransferase
FNA65_RS15330	COG1011	Hydrolase
FNA65_RS15340	COG2823	Periplasmic or secreted lipoprotein
FNA65_RS15350	COG4667	esterase of the alpha-beta hydrolase superfamily
FNA65_RS15355	COG0084	hydrolase, TatD family'
FNA65_RS15360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNA65_RS15405	COG3726	membrane protein affecting hemolysin expression
FNA65_RS15410	COG0560	Phosphoserine phosphatase
FNA65_RS15415	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FNA65_RS15420	COG1056	cytidyltransferase-related domain
FNA65_RS15420	COG3172	ATPase kinase involved in NAD metabolism
FNA65_RS15425	COG0488	(ABC) transporter
FNA65_RS15430	COG0741	lytic transglycosylase activity
FNA65_RS15450	COG3708	Transcriptional regulator
FNA65_RS15450	COG2207	Transcriptional regulator
FNA65_RS15455	COG3045	CreA protein
FNA65_RS15460	COG0745	RESPONSE REGULATOR receiver
FNA65_RS15465	COG2205	protein histidine kinase activity
FNA65_RS15470	COG4452	Inner membrane protein CreD
FNA65_RS15475	COG0745	RESPONSE REGULATOR receiver
FNA65_RS15485	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FNA65_RS15495	COG0527	aspartate kinase activity
FNA65_RS15495	COG0460	homoserine dehydrogenase
FNA65_RS15505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNA65_RS15520	COG1115	amino acid carrier protein
FNA65_RS15530	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNA65_RS15535	COG1584	GPR1 FUN34 yaaH family protein
FNA65_RS15540	COG4735	regulation of single-species biofilm formation
FNA65_RS15585	COG0583	DNA-binding transcription factor activity
FNA65_RS15600	COG4372	Transposase
FNA65_RS15630	COG0196	riboflavin kinase activity
FNA65_RS15645	COG1047	Peptidyl-prolyl cis-trans
FNA65_RS15665	COG0505	Belongs to the CarA family
FNA65_RS15670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNA65_RS15695	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNA65_RS15720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNA65_RS15730	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FNA65_RS15735	COG0564	pseudouridine synthase activity
FNA65_RS15745	COG0417	DNA replication proofreading
FNA65_RS15750	COG0235	Class ii aldolase
FNA65_RS15765	COG4977	sequence-specific DNA binding
FNA65_RS15770	COG0586	Pfam SNARE associated Golgi protein
FNA65_RS15780	COG1178	ABC-type Fe3 transport system permease component
FNA65_RS15785	COG4143	(ABC) transporter
FNA65_RS15800	COG2814	Major facilitator Superfamily
FNA65_RS15830	COG0583	DNA-binding transcription factor activity
FNA65_RS15840	COG0440	acetolactate synthase activity
FNA65_RS15850	COG1609	Transcriptional regulator
FNA65_RS15865	COG3116	cell division
FNA65_RS15870	COG0768	penicillin binding
FNA65_RS15875	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNA65_RS15880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FNA65_RS15895	COG0772	Belongs to the SEDS family
FNA65_RS15910	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNA65_RS15915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FNA65_RS15920	COG0849	cell division
FNA65_RS15925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNA65_RS15945	COG0494	nUDIX hydrolase
FNA65_RS15960	COG0237	dephospho-CoA kinase activity
FNA65_RS15975	COG4372	Transposase
FNA65_RS15980	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS16015	COG0157	Belongs to the NadC ModD family
FNA65_RS16020	COG3023	N-Acetylmuramoyl-L-alanine amidase
FNA65_RS16025	COG3725	Membrane protein required for beta-lactamase induction
FNA65_RS16030	COG1113	amino acid transport
FNA65_RS16035	COG2186	Transcriptional regulator
FNA65_RS16040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNA65_RS16045	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNA65_RS16050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNA65_RS16055	COG3064	Membrane
FNA65_RS16060	COG1049	propionate catabolic process, 2-methylcitrate cycle
FNA65_RS16085	COG2132	Multicopper oxidase
FNA65_RS16090	COG4993	Dehydrogenase
FNA65_RS16095	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FNA65_RS16100	COG0288	reversible hydration of carbon dioxide
FNA65_RS16105	COG1131	(ABC) transporter
FNA65_RS16110	COG0842	Transport permease protein
FNA65_RS16115	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS16125	COG0726	polysaccharide deacetylase
FNA65_RS16135	COG5464	transposase or invertase
FNA65_RS16180	COG3539	Fimbrial protein
FNA65_RS16185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FNA65_RS16190	COG0617	tRNA 3'-terminal CCA addition
FNA65_RS16200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FNA65_RS16210	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FNA65_RS16215	COG1643	Atp-dependent helicase
FNA65_RS16220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNA65_RS16225	COG4774	siderophore transport
FNA65_RS16230	COG1120	ATPase activity
FNA65_RS16235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNA65_RS16240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNA65_RS16265	COG2860	membrane
FNA65_RS16270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNA65_RS16285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNA65_RS16290	COG3835	regulator
FNA65_RS16305	COG1408	metallophosphoesterase
FNA65_RS16320	COG0024	Methionine aminopeptidase
FNA65_RS16345	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FNA65_RS16355	COG0575	Belongs to the CDS family
FNA65_RS16360	COG0750	zinc metalloprotease
FNA65_RS16370	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FNA65_RS16375	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNA65_RS16400	COG0587	DNA-directed DNA polymerase activity
FNA65_RS16410	COG1982	Orn Lys Arg decarboxylase major
FNA65_RS16415	COG0346	lactoylglutathione lyase activity
FNA65_RS16425	COG4568	rho-dependent transcription termination
FNA65_RS16435	COG4681	YaeQ
FNA65_RS16440	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FNA65_RS16445	COG3015	lipoprotein NlpE involved in copper resistance
FNA65_RS16450	COG0791	NLP P60 protein
FNA65_RS16460	COG1720	tRNA m6t6A37 methyltransferase activity
FNA65_RS16470	COG1464	Belongs to the NlpA lipoprotein family
FNA65_RS16475	COG2011	ABC-type metal ion transport system permease component
FNA65_RS16480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNA65_RS16485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FNA65_RS16520	COG0656	L-ascorbic acid biosynthetic process
FNA65_RS16525	COG0583	DNA-binding transcription factor activity
FNA65_RS16535	COG2226	methyltransferase
FNA65_RS16540	COG1388	LysM domain
FNA65_RS16540	COG0741	lytic transglycosylase activity
FNA65_RS16550	COG2226	methyltransferase
FNA65_RS16560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNA65_RS16575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNA65_RS16585	COG1960	acyl-CoA dehydrogenase activity
FNA65_RS16595	COG0121	glutamine amidotransferase
FNA65_RS16600	COG3034	peptidoglycan biosynthetic process
FNA65_RS16610	COG0791	NLP P60 protein
FNA65_RS16640	COG0454	-acetyltransferase
FNA65_RS16645	COG1690	Belongs to the RtcB family
FNA65_RS16650	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS16665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FNA65_RS16670	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNA65_RS16690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FNA65_RS16735	COG4197	protein conserved in bacteria, prophage-related
FNA65_RS16740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNA65_RS16770	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS16775	COG4372	Transposase
FNA65_RS16780	COG1556	Lactate utilization protein
FNA65_RS16785	COG1139	Iron-sulfur cluster binding protein
FNA65_RS16790	COG0247	lactate metabolic process
FNA65_RS16800	COG2207	Transcriptional regulator
FNA65_RS16840	COG3059	membrane
FNA65_RS16845	COG0656	L-ascorbic acid biosynthetic process
FNA65_RS16850	COG3708	Transcriptional regulator
FNA65_RS16850	COG2207	Transcriptional regulator
FNA65_RS16875	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS16895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNA65_RS16900	COG4521	taurine ABC transporter
FNA65_RS16910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNA65_RS16915	COG2175	clavaminate synthase activity
FNA65_RS16930	COG0113	porphobilinogen synthase activity
FNA65_RS16955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNA65_RS16960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNA65_RS16965	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FNA65_RS16985	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNA65_RS16995	COG1785	Belongs to the alkaline phosphatase family
FNA65_RS17005	COG3706	GGDEF domain
FNA65_RS17010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNA65_RS17030	COG4126	flavin adenine dinucleotide binding
FNA65_RS17055	COG1940	carbohydrate kinase activity
FNA65_RS17060	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS17070	COG2814	Major facilitator Superfamily
FNA65_RS17075	COG0419	ATPase involved in DNA repair
FNA65_RS17080	COG0420	3'-5' exonuclease activity
FNA65_RS17085	COG0745	RESPONSE REGULATOR receiver
FNA65_RS17090	COG5002	protein histidine kinase activity
FNA65_RS17095	COG1114	Component of the transport system for branched-chain amino acids
FNA65_RS17100	COG1113	amino acid transport
FNA65_RS17125	COG1862	Preprotein translocase
FNA65_RS17130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNA65_RS17135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNA65_RS17140	COG1403	HNH endonuclease
FNA65_RS17150	COG3248	Nucleoside-binding outer membrane protein
FNA65_RS17165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNA65_RS17165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNA65_RS17180	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FNA65_RS17185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FNA65_RS17190	COG0667	Aldo Keto reductase
FNA65_RS17200	COG0142	geranyltranstransferase activity
FNA65_RS17215	COG0693	protein deglycase activity
FNA65_RS17220	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNA65_RS17230	COG2814	Major facilitator Superfamily
FNA65_RS17240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FNA65_RS17245	COG1845	cytochrome c oxidase, subunit III
FNA65_RS17250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNA65_RS17255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNA65_RS17260	COG2223	nitrite transmembrane transporter activity
FNA65_RS17265	COG3056	Lipoprotein
FNA65_RS17270	COG0271	Belongs to the BolA IbaG family
FNA65_RS17290	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNA65_RS17295	COG0776	regulation of translation
FNA65_RS17300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNA65_RS17305	COG1555	photosystem II stabilization
FNA65_RS17310	COG0824	Thioesterase
FNA65_RS17320	COG4533	DNA binding
FNA65_RS17330	COG1522	sequence-specific DNA binding
FNA65_RS17335	COG1132	(ABC) transporter
FNA65_RS17360	COG0347	Belongs to the P(II) protein family
FNA65_RS17365	COG0004	ammonium transporteR
FNA65_RS17370	COG1946	Acyl-CoA thioesterase
FNA65_RS17380	COG3385	transposase activity
FNA65_RS17385	COG3695	enzyme binding
FNA65_RS17395	COG5507	3-demethylubiquinone-9 3-methyltransferase
FNA65_RS17400	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FNA65_RS17415	COG0110	maltose O-acetyltransferase activity
FNA65_RS17430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNA65_RS17435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNA65_RS17440	COG1309	transcriptional regulator
FNA65_RS17445	COG1196	nuclear chromosome segregation
FNA65_RS17445	COG3264	Mechanosensitive ion channel
FNA65_RS17455	COG3923	Primosomal replication protein n
FNA65_RS17470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNA65_RS17505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA65_RS17510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNA65_RS17510	COG4651	solute:proton antiporter activity
FNA65_RS17515	COG2223	nitrite transmembrane transporter activity
FNA65_RS17530	COG0737	Belongs to the 5'-nucleotidase family
FNA65_RS17535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNA65_RS17540	COG3735	TraB family
FNA65_RS17550	COG3093	addiction module antidote protein HigA
FNA65_RS17555	COG2217	Heavy metal translocating P-type atpase
FNA65_RS17565	COG0531	amino acid
FNA65_RS17570	COG0789	Transcriptional regulator
FNA65_RS17575	COG1585	Membrane protein implicated in regulation of membrane protease activity
FNA65_RS17580	COG0330	HflC and HflK could
FNA65_RS17585	COG4619	ABC transporter
FNA65_RS17590	COG0390	transport system, permease component
FNA65_RS17595	COG3118	belongs to the thioredoxin family
FNA65_RS17600	COG0300	oxidoreductase activity
FNA65_RS17605	COG2755	lipolytic protein G-D-S-L family
FNA65_RS17610	COG4181	ATPase activity
FNA65_RS17615	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FNA65_RS17660	COG1414	Transcriptional regulator
FNA65_RS17665	COG3960	tartronate-semialdehyde synthase activity
FNA65_RS17670	COG3622	Belongs to the hyi family
FNA65_RS17695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FNA65_RS17710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FNA65_RS17715	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FNA65_RS17725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNA65_RS17735	COG1988	membrane-bound metal-dependent
FNA65_RS17740	COG2501	S4 domain
FNA65_RS17755	COG2197	response regulator
FNA65_RS17785	COG1113	amino acid transport
FNA65_RS17790	COG0668	transmembrane transport
FNA65_RS17795	COG0778	Nitroreductase
FNA65_RS17800	COG2315	Protein conserved in bacteria
FNA65_RS17810	COG3385	transposase activity
FNA65_RS17855	COG2977	Belongs to the P-Pant transferase superfamily
FNA65_RS17860	COG4771	TonB-dependent receptor
FNA65_RS17865	COG2382	esterase
FNA65_RS17870	COG3251	PFAM MbtH domain protein
FNA65_RS17875	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FNA65_RS17875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNA65_RS17880	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FNA65_RS17885	COG1120	ATPase activity
FNA65_RS17890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNA65_RS17895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNA65_RS17905	COG4592	Periplasmic binding protein
FNA65_RS17910	COG1169	isochorismate synthase
FNA65_RS17915	COG1021	2,3-dihydroxybenzoate-AMP ligase
FNA65_RS17920	COG1535	isochorismatase
FNA65_RS17920	COG3433	isochorismatase activity
FNA65_RS17925	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS17930	COG2050	protein possibly involved in aromatic compounds catabolism
FNA65_RS17935	COG1966	Carbon starvation protein
FNA65_RS17940	COG2879	small protein
FNA65_RS17945	COG0371	Dehydrogenase
FNA65_RS17970	COG3969	phosphoadenosine phosphosulfate
FNA65_RS17985	COG4372	Transposase
FNA65_RS17990	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS18020	COG0450	alkyl hydroperoxide reductase
FNA65_RS18025	COG3634	alkyl hydroperoxide reductase activity
FNA65_RS18030	COG0589	response to stress
FNA65_RS18040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNA65_RS18045	COG3719	Belongs to the RNase T2 family
FNA65_RS18065	COG3051	citrate lyase alpha subunit
FNA65_RS18070	COG2301	Belongs to the HpcH HpaI aldolase family
FNA65_RS18080	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FNA65_RS18100	COG4565	transcriptional regulatory protein
FNA65_RS18105	COG3069	C4-dicarboxylate transmembrane transporter activity
FNA65_RS18125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNA65_RS18130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNA65_RS18160	COG1686	Belongs to the peptidase S11 family
FNA65_RS18165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FNA65_RS18170	COG0772	Belongs to the SEDS family
FNA65_RS18175	COG0768	penicillin binding
FNA65_RS18185	COG0799	negative regulation of ribosome biogenesis
FNA65_RS18200	COG1466	dna polymerase III delta subunit
FNA65_RS18215	COG2888	peptidyl-tyrosine sulfation
FNA65_RS18220	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FNA65_RS18240	COG2214	Heat shock protein DnaJ domain protein
FNA65_RS18245	COG2214	Heat shock protein DnaJ domain protein
FNA65_RS18255	COG2214	Heat shock protein DnaJ domain protein
FNA65_RS18260	COG0443	Heat shock 70 kDa protein
FNA65_RS18270	COG1126	abc transporter atp-binding protein
FNA65_RS18275	COG0765	amino acid transport
FNA65_RS18280	COG0765	amino acid transport
FNA65_RS18300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FNA65_RS18305	COG4535	Mg2 and Co2 transporter CorC
FNA65_RS18315	COG1702	phosphate starvation-inducible protein PhoH
FNA65_RS18325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNA65_RS18365	COG0367	asparagine synthase
FNA65_RS18370	COG0647	UMP catabolic process
FNA65_RS18375	COG1940	carbohydrate kinase activity
FNA65_RS18375	COG1846	Transcriptional regulator
FNA65_RS18380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FNA65_RS18390	COG1263	PTS System
FNA65_RS18390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNA65_RS18390	COG2190	(PTS) system
FNA65_RS18410	COG0735	belongs to the Fur family
FNA65_RS18420	COG0716	FMN binding
FNA65_RS18430	COG0596	Alpha beta hydrolase
FNA65_RS18435	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FNA65_RS18440	COG0033	Phosphoglucomutase
FNA65_RS18465	COG0745	RESPONSE REGULATOR receiver
FNA65_RS18470	COG2205	protein histidine kinase activity
FNA65_RS18520	COG3209	COG3209 Rhs family protein
FNA65_RS18545	COG3272	Protein of unknown function (DUF1722)
FNA65_RS18550	COG0415	Belongs to the DNA photolyase family
FNA65_RS18560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FNA65_RS18565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNA65_RS18570	COG1984	allophanate hydrolase subunit 2
FNA65_RS18585	COG3180	Ammonia monooxygenase
FNA65_RS18595	COG3121	Chaperone
FNA65_RS18600	COG3188	usher protein
FNA65_RS18615	COG0372	Belongs to the citrate synthase family
FNA65_RS18625	COG2009	succinate dehydrogenase
FNA65_RS18630	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FNA65_RS18640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNA65_RS18645	COG0567	Dehydrogenase, E1 component
FNA65_RS18650	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNA65_RS18660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FNA65_RS18665	COG2188	Transcriptional regulator
FNA65_RS18670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNA65_RS18670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS18670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNA65_RS18705	COG1271	oxidase subunit
FNA65_RS18710	COG1294	oxidase, subunit
FNA65_RS18715	COG4890	Cyd operon protein YbgT
FNA65_RS18720	COG3790	cyd operon protein YbgE
FNA65_RS18725	COG0824	Thioesterase
FNA65_RS18730	COG0811	peptide transport
FNA65_RS18735	COG0848	biopolymer transport protein
FNA65_RS18740	COG3064	Membrane
FNA65_RS18750	COG2885	chlorophyll binding
FNA65_RS18755	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FNA65_RS18795	COG3201	nicotinamide mononucleotide transporter
FNA65_RS18800	COG1230	cation diffusion facilitator family transporter
FNA65_RS18810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FNA65_RS18820	COG2017	converts alpha-aldose to the beta-anomer
FNA65_RS18830	COG1085	galactose-1-phosphate uridylyltransferase
FNA65_RS18835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FNA65_RS18840	COG1119	ATPase activity
FNA65_RS18845	COG2005	Transcriptional regulator
FNA65_RS18845	COG3585	molybdate ion transport
FNA65_RS18860	COG4149	molybdate abc transporter
FNA65_RS18870	COG0561	phosphatase activity
FNA65_RS18875	COG0582	viral genome integration into host DNA
FNA65_RS18900	COG1396	sequence-specific DNA binding
FNA65_RS18910	COG3646	Phage regulatory protein
FNA65_RS18955	COG4372	Transposase
FNA65_RS18960	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS18990	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS18995	COG4372	Transposase
FNA65_RS19035	COG2205	protein histidine kinase activity
FNA65_RS19035	COG0784	Response regulator, receiver
FNA65_RS19040	COG2197	response regulator
FNA65_RS19045	COG2198	Histidine kinase
FNA65_RS19045	COG0642	Histidine kinase
FNA65_RS19050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FNA65_RS19055	COG1477	protein flavinylation
FNA65_RS19060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNA65_RS19060	COG2169	Transcriptional regulator
FNA65_RS19065	COG3145	DNA-N1-methyladenine dioxygenase activity
FNA65_RS19070	COG4615	Cyclic peptide transporter
FNA65_RS19085	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNA65_RS19085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNA65_RS19090	COG3062	negative regulation of establishment of protein localization
FNA65_RS19100	COG0437	4 iron, 4 sulfur cluster binding
FNA65_RS19105	COG0348	domain, Protein
FNA65_RS19110	COG3043	anaerobic respiration
FNA65_RS19115	COG3005	denitrification pathway
FNA65_RS19125	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNA65_RS19130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNA65_RS19135	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNA65_RS19145	COG1138	Cytochrome C-type biogenesis protein
FNA65_RS19150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNA65_RS19155	COG4235	cytochrome complex assembly
FNA65_RS19155	COG3088	subunit of a heme lyase
FNA65_RS19160	COG2197	response regulator
FNA65_RS19180	COG3083	sulfuric ester hydrolase activity
FNA65_RS19200	COG1061	Type III restriction enzyme res subunit
FNA65_RS19205	COG1187	pseudouridine synthase activity
FNA65_RS19220	COG4172	Belongs to the ABC transporter superfamily
FNA65_RS19225	COG4239	(ABC) transporter, permease
FNA65_RS19230	COG4174	ABC transporter (Permease)
FNA65_RS19235	COG4166	transmembrane transport
FNA65_RS19240	COG2200	EAL domain
FNA65_RS19245	COG0791	NLP P60 protein
FNA65_RS19250	COG0671	phosphoesterase, PA-phosphatase related
FNA65_RS19255	COG0523	cobalamin synthesis protein
FNA65_RS19285	COG2814	Major facilitator Superfamily
FNA65_RS19290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS19290	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS19295	COG1105	Belongs to the carbohydrate kinase PfkB family
FNA65_RS19300	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FNA65_RS19300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNA65_RS19300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNA65_RS19310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA65_RS19315	COG2313	pseudouridylate synthase activity
FNA65_RS19320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNA65_RS19335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNA65_RS19340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA65_RS19340	COG1522	sequence-specific DNA binding
FNA65_RS19350	COG2855	membrane
FNA65_RS19355	COG0583	DNA-binding transcription factor activity
FNA65_RS19360	COG0833	amino acid
FNA65_RS19380	COG2311	Membrane
FNA65_RS19390	COG1879	ABC-type sugar transport system periplasmic component
FNA65_RS19405	COG1129	ABC transporter
FNA65_RS19425	COG4211	Belongs to the binding-protein-dependent transport system permease family
FNA65_RS19430	COG0167	dihydroorotate dehydrogenase activity
FNA65_RS19430	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FNA65_RS19445	COG2949	membrane
FNA65_RS19455	COG1346	cytolysis
FNA65_RS19480	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS19495	COG1686	Belongs to the peptidase S11 family
FNA65_RS19500	COG0277	FAD linked oxidase domain protein
FNA65_RS19505	COG1472	Belongs to the glycosyl hydrolase 3 family
FNA65_RS19515	COG1174	glycine betaine transport
FNA65_RS19520	COG1125	glycine betaine transport
FNA65_RS19525	COG1174	glycine betaine transport
FNA65_RS19540	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS19545	COG4372	Transposase
FNA65_RS19560	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS19570	COG5455	response to cobalt ion
FNA65_RS19585	COG3539	Fimbrial protein
FNA65_RS19595	COG0489	protein tyrosine kinase activity
FNA65_RS19640	COG4807	Protein conserved in bacteria
FNA65_RS19645	COG3279	Response regulator of the LytR AlgR family
FNA65_RS19650	COG3275	phosphorelay sensor kinase activity
FNA65_RS19680	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FNA65_RS19685	COG5301	cellulose 1,4-beta-cellobiosidase activity
FNA65_RS19835	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS19840	COG4372	Transposase
FNA65_RS19860	COG3443	Belongs to the bacterial solute-binding protein 9 family
FNA65_RS19875	COG2351	hydroxyisourate hydrolase activity
FNA65_RS19880	COG0745	RESPONSE REGULATOR receiver
FNA65_RS19885	COG2205	protein histidine kinase activity
FNA65_RS19905	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FNA65_RS19925	COG1418	mRNA catabolic process
FNA65_RS19930	COG0270	DNA (cytosine-5-)-methyltransferase activity
FNA65_RS19935	COG3727	T/G mismatch-specific endonuclease activity
FNA65_RS20035	COG3772	lysozyme
FNA65_RS20075	COG1560	Kdo2-lipid A biosynthetic process
FNA65_RS20080	COG0739	heme binding
FNA65_RS20085	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FNA65_RS20095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNA65_RS20135	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FNA65_RS20150	COG1376	ErfK ybiS ycfS ynhG family protein
FNA65_RS20160	COG0583	DNA-binding transcription factor activity
FNA65_RS20165	COG0583	DNA-binding transcription factor activity
FNA65_RS20205	COG0582	viral genome integration into host DNA
FNA65_RS20225	COG0217	transcriptional regulatory protein
FNA65_RS20230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNA65_RS20245	COG0477	Major facilitator Superfamily
FNA65_RS20305	COG4372	Transposase
FNA65_RS20310	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS20320	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS20325	COG1403	HNH endonuclease
FNA65_RS20365	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS20370	COG4372	Transposase
FNA65_RS20400	COG3778	Protein conserved in bacteria
FNA65_RS20435	COG0500	methyltransferase
FNA65_RS20460	COG1877	trehalose-phosphatase activity
FNA65_RS20465	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA65_RS20475	COG1879	ABC-type sugar transport system periplasmic component
FNA65_RS20480	COG1528	Iron-storage protein
FNA65_RS20505	COG1528	Iron-storage protein
FNA65_RS20515	COG0814	amino acid
FNA65_RS20520	COG3318	Belongs to the UPF0149 family
FNA65_RS20520	COG3012	SEC-C Motif Domain Protein
FNA65_RS20550	COG2197	response regulator
FNA65_RS20565	COG2197	response regulator
FNA65_RS20570	COG1126	abc transporter atp-binding protein
FNA65_RS20575	COG0765	amino acid transport
FNA65_RS20585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA65_RS20605	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FNA65_RS20610	COG1516	flagellar protein fliS
FNA65_RS20620	COG0366	Alpha amylase catalytic
FNA65_RS20630	COG2391	methyltransferase activity
FNA65_RS20635	COG0425	Belongs to the sulfur carrier protein TusA family
FNA65_RS20640	COG2135	peptidase activity
FNA65_RS20645	COG0675	Transposase, IS605 OrfB family
FNA65_RS20660	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FNA65_RS20665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FNA65_RS20670	COG3190	flagellar
FNA65_RS20675	COG1338	Plays a role in the flagellum-specific transport system
FNA65_RS20680	COG1987	bacterial-type flagellum assembly
FNA65_RS20685	COG1684	flagellar biosynthetic protein fliR
FNA65_RS20690	COG2197	response regulator
FNA65_RS20720	COG5475	Uncharacterized small protein (DUF2158)
FNA65_RS20725	COG2354	Protein conserved in bacteria
FNA65_RS20755	COG2433	Pfam Transposase IS66
FNA65_RS20805	COG5301	cellulose 1,4-beta-cellobiosidase activity
FNA65_RS20850	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS20855	COG1335	isochorismatase
FNA65_RS20865	COG0494	nUDIX hydrolase
FNA65_RS20870	COG0217	transcriptional regulatory protein
FNA65_RS20890	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS20895	COG4372	Transposase
FNA65_RS20905	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS20930	COG2003	Belongs to the UPF0758 family
FNA65_RS20960	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS20980	COG0351	phosphomethylpyrimidine kinase
FNA65_RS20985	COG3757	hydrolase, family 25
FNA65_RS20990	COG2188	Transcriptional regulator
FNA65_RS20995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA65_RS21000	COG1397	ADP-ribosylglycohydrolase
FNA65_RS21005	COG2211	Major facilitator Superfamily
FNA65_RS21010	COG1830	Aldolase
FNA65_RS21025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS21030	COG3414	Phosphotransferase system galactitol-specific IIB component
FNA65_RS21035	COG3775	system Galactitol-specific IIC component
FNA65_RS21040	COG1063	alcohol dehydrogenase
FNA65_RS21065	COG0826	peptidase U32
FNA65_RS21075	COG3609	addiction module antidote protein, CC2985 family
FNA65_RS21085	COG0745	RESPONSE REGULATOR receiver
FNA65_RS21090	COG2205	protein histidine kinase activity
FNA65_RS21130	COG4245	von Willebrand factor, type A
FNA65_RS21135	COG0631	protein serine/threonine phosphatase activity
FNA65_RS21140	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FNA65_RS21145	COG0443	Heat shock 70 kDa protein
FNA65_RS21150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FNA65_RS21155	COG5002	protein histidine kinase activity
FNA65_RS21155	COG5001	Diguanylate cyclase
FNA65_RS21155	COG3447	MASE1 domain protein
FNA65_RS21160	COG0572	uridine kinase
FNA65_RS21170	COG2982	Protein involved in outer membrane biogenesis
FNA65_RS21175	COG1253	flavin adenine dinucleotide binding
FNA65_RS21180	COG1596	polysaccharide export
FNA65_RS21185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNA65_RS21190	COG3206	protein involved in exopolysaccharide biosynthesis
FNA65_RS21190	COG0489	protein tyrosine kinase activity
FNA65_RS21195	COG0463	Glycosyl transferase, family 2
FNA65_RS21200	COG1045	serine acetyltransferase
FNA65_RS21205	COG0438	transferase activity, transferring glycosyl groups
FNA65_RS21215	COG1216	Glycosyl transferase, family 2
FNA65_RS21220	COG0110	maltose O-acetyltransferase activity
FNA65_RS21225	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FNA65_RS21230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNA65_RS21235	COG1051	belongs to the nudix hydrolase family
FNA65_RS21240	COG0297	glycogen (starch) synthase activity
FNA65_RS21245	COG0662	Cupin 2, conserved barrel domain protein
FNA65_RS21245	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FNA65_RS21250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNA65_RS21255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNA65_RS21260	COG2244	polysaccharide biosynthetic process
FNA65_RS21265	COG2327	Polysaccharide pyruvyl transferase
FNA65_RS21270	COG0438	transferase activity, transferring glycosyl groups
FNA65_RS21280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNA65_RS21285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNA65_RS21290	COG1088	dTDP-glucose 4,6-dehydratase activity
FNA65_RS21335	COG0438	transferase activity, transferring glycosyl groups
FNA65_RS21340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNA65_RS21365	COG0140	phosphoribosyl-ATP diphosphatase activity
FNA65_RS21365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNA65_RS21380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNA65_RS21385	COG0131	Imidazoleglycerol-phosphate dehydratase
FNA65_RS21385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FNA65_RS21395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNA65_RS21410	COG2161	toxin-antitoxin pair type II binding
FNA65_RS21415	COG4115	mRNA cleavage
FNA65_RS21420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNA65_RS21425	COG0583	DNA-binding transcription factor activity
FNA65_RS21435	COG0531	amino acid
FNA65_RS21440	COG2391	methyltransferase activity
FNA65_RS21445	COG0425	Belongs to the sulfur carrier protein TusA family
FNA65_RS21450	COG2925	Exonuclease
FNA65_RS21485	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS21510	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS21565	COG3772	lysozyme
FNA65_RS21625	COG0484	heat shock protein binding
FNA65_RS21630	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FNA65_RS21650	COG1484	DNA-dependent DNA replication
FNA65_RS21675	COG3646	Phage regulatory protein
FNA65_RS21690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNA65_RS21785	COG0789	Transcriptional regulator
FNA65_RS21790	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS21835	COG2850	peptidyl-arginine hydroxylation
FNA65_RS21840	COG2205	protein histidine kinase activity
FNA65_RS21850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNA65_RS21870	COG1187	pseudouridine synthase activity
FNA65_RS21875	COG0538	isocitrate dehydrogenase activity
FNA65_RS21890	COG5562	phage envelope protein
FNA65_RS21895	COG0789	Transcriptional regulator
FNA65_RS21900	COG2200	EAL domain
FNA65_RS21980	COG2894	cell division
FNA65_RS22010	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNA65_RS22025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNA65_RS22050	COG2719	SpoVR family
FNA65_RS22060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNA65_RS22070	COG1619	proteins homologs of microcin C7 resistance protein MccF
FNA65_RS22080	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FNA65_RS22105	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FNA65_RS22105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA65_RS22105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNA65_RS22110	COG1461	Dihydroxyacetone kinase
FNA65_RS22115	COG2376	Dihydroxyacetone kinase
FNA65_RS22120	COG3284	Transcriptional regulator
FNA65_RS22140	COG0012	GTP binding
FNA65_RS22155	COG0659	secondary active sulfate transmembrane transporter activity
FNA65_RS22160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNA65_RS22185	COG2890	protein-(glutamine-N5) methyltransferase activity
FNA65_RS22190	COG3094	Invasion gene expression up-regulator, SirB
FNA65_RS22195	COG2912	Transglutaminase-like superfamily
FNA65_RS22235	COG0387	Pfam Sodium calcium exchanger
FNA65_RS22240	COG4572	Cation transport regulator
FNA65_RS22245	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FNA65_RS22250	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FNA65_RS22255	COG4932	domain protein
FNA65_RS22260	COG2197	response regulator
FNA65_RS22265	COG3850	Histidine kinase
FNA65_RS22275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FNA65_RS22280	COG1140	nitrate reductase beta subunit
FNA65_RS22285	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FNA65_RS22290	COG2181	nitrate reductase activity
FNA65_RS22310	COG0788	formyltetrahydrofolate deformylase activity
FNA65_RS22320	COG1752	Esterase of the alpha-beta hydrolase superfamily
FNA65_RS22325	COG0745	RESPONSE REGULATOR receiver
FNA65_RS22330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNA65_RS22340	COG1435	thymidine kinase activity
FNA65_RS22350	COG1454	alcohol dehydrogenase
FNA65_RS22350	COG1012	belongs to the aldehyde dehydrogenase family
FNA65_RS22355	COG2095	MarC family integral membrane protein
FNA65_RS22370	COG4166	transmembrane transport
FNA65_RS22375	COG0601	transmembrane transport
FNA65_RS22380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA65_RS22385	COG0444	Belongs to the ABC transporter superfamily
FNA65_RS22390	COG4608	Belongs to the ABC transporter superfamily
FNA65_RS22410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNA65_RS22415	COG2350	Protein conserved in bacteria
FNA65_RS22425	COG1607	acyl-coa hydrolase
FNA65_RS22445	COG3047	cAMP biosynthetic process
FNA65_RS22465	COG0135	phosphoribosylanthranilate isomerase activity
FNA65_RS22465	COG0134	indole-3-glycerol-phosphate synthase activity
FNA65_RS22470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNA65_RS22470	COG0512	Glutamine amidotransferase of anthranilate synthase
FNA65_RS22475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNA65_RS22485	COG0613	PHP domain protein
FNA65_RS22490	COG0009	L-threonylcarbamoyladenylate synthase
FNA65_RS22495	COG4907	membrane protein (DUF2207)
FNA65_RS22500	COG1187	pseudouridine synthase activity
FNA65_RS22510	COG1028	Short-chain dehydrogenase reductase Sdr
FNA65_RS22515	COG0616	signal peptide processing
FNA65_RS22525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNA65_RS22535	COG0583	DNA-binding transcription factor activity
FNA65_RS22565	COG0671	phosphoesterase, PA-phosphatase related
FNA65_RS22570	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FNA65_RS22575	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FNA65_RS22585	COG0023	Translation Initiation Factor
FNA65_RS22600	COG1349	DNA-binding transcription factor activity
FNA65_RS22610	COG5001	Diguanylate cyclase
FNA65_RS22630	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNA65_RS22630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNA65_RS22635	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNA65_RS22640	COG2852	Protein conserved in bacteria
FNA65_RS22645	COG4172	Belongs to the ABC transporter superfamily
FNA65_RS22650	COG4172	Belongs to the ABC transporter superfamily
FNA65_RS22660	COG4168	peptide transport system, permease
FNA65_RS22665	COG4166	transmembrane transport
FNA65_RS22675	COG0531	amino acid
FNA65_RS22685	COG0174	glutamine synthetase
FNA65_RS22695	COG1396	sequence-specific DNA binding
FNA65_RS22695	COG1917	Cupin 2, conserved barrel domain protein
FNA65_RS22700	COG1012	belongs to the aldehyde dehydrogenase family
FNA65_RS22705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNA65_RS22710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNA65_RS22715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FNA65_RS22720	COG1842	Phage shock protein A
FNA65_RS22730	COG1983	PspC domain protein
FNA65_RS22740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNA65_RS22745	COG0366	Alpha amylase catalytic
FNA65_RS22775	COG1609	Transcriptional regulator
FNA65_RS22780	COG3106	COG3106 Predicted ATPase
FNA65_RS22790	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FNA65_RS22795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FNA65_RS22800	COG4948	Mandelate Racemase Muconate Lactonizing
FNA65_RS22805	COG2866	Carboxypeptidase
FNA65_RS22830	COG1073	alpha beta
FNA65_RS22840	COG0583	DNA-binding transcription factor activity
FNA65_RS22850	COG0668	transmembrane transport
FNA65_RS22860	COG3182	Iron-regulated membrane protein
FNA65_RS22865	COG0589	response to stress
FNA65_RS22870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNA65_RS22875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNA65_RS22895	COG1473	amidohydrolase
FNA65_RS22905	COG0583	DNA-binding transcription factor activity
FNA65_RS22910	COG2840	Smr protein MutS2
FNA65_RS22915	COG3706	GGDEF domain
FNA65_RS22925	COG0513	Belongs to the DEAD box helicase family
FNA65_RS22960	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FNA65_RS23020	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS23040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNA65_RS23045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNA65_RS23050	COG1121	(ABC) transporter
FNA65_RS23060	COG0589	response to stress
FNA65_RS23065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FNA65_RS23070	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNA65_RS23070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNA65_RS23070	COG1013	pyruvate-flavodoxin oxidoreductase activity
FNA65_RS23070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNA65_RS23075	COG3042	response to heat
FNA65_RS23080	COG3187	Heat shock protein
FNA65_RS23085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNA65_RS23090	COG2911	Protein conserved in bacteria
FNA65_RS23100	COG3784	Protein of unknown function (DUF1318)
FNA65_RS23110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNA65_RS23130	COG0671	phosphoesterase, PA-phosphatase related
FNA65_RS23130	COG2453	phosphatase
FNA65_RS23140	COG1643	Atp-dependent helicase
FNA65_RS23145	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FNA65_RS23150	COG1012	belongs to the aldehyde dehydrogenase family
FNA65_RS23165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNA65_RS23170	COG3038	cytochrome b561
FNA65_RS23190	COG4372	Transposase
FNA65_RS23195	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS23205	COG0840	transmembrane signaling receptor activity
FNA65_RS23210	COG0583	DNA-binding transcription factor activity
FNA65_RS23215	COG5383	Protein conserved in bacteria
FNA65_RS23225	COG2841	Protein conserved in bacteria
FNA65_RS23230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNA65_RS23235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FNA65_RS23240	COG4372	Transposase
FNA65_RS23245	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS23255	COG0840	transmembrane signaling receptor activity
FNA65_RS23260	COG0583	DNA-binding transcription factor activity
FNA65_RS23265	COG5383	Protein conserved in bacteria
FNA65_RS23275	COG2841	Protein conserved in bacteria
FNA65_RS23280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNA65_RS23285	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FNA65_RS23290	COG4372	Transposase
FNA65_RS23295	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS23310	COG1275	C4-dicarboxylate transporter malic acid transport protein
FNA65_RS23315	COG0500	methyltransferase
FNA65_RS23355	COG4372	Transposase
FNA65_RS23375	COG2723	6-phospho-beta-galactosidase activity
FNA65_RS23395	COG4977	sequence-specific DNA binding
FNA65_RS23400	COG1846	Transcriptional regulator
FNA65_RS23405	COG2095	MarC family integral membrane protein
FNA65_RS23425	COG0583	DNA-binding transcription factor activity
FNA65_RS23430	COG1012	belongs to the aldehyde dehydrogenase family
FNA65_RS23435	COG2066	Belongs to the glutaminase family
FNA65_RS23445	COG2199	diguanylate cyclase activity
FNA65_RS23465	COG3781	membrane
FNA65_RS23520	COG1802	Transcriptional regulator
FNA65_RS23525	COG4221	oxidoreductase activity
FNA65_RS23530	COG0339	signal peptide processing
FNA65_RS23535	COG1546	Belongs to the CinA family
FNA65_RS23540	COG3111	PFAM Bacterial OB fold (BOF) protein
FNA65_RS23545	COG3706	GGDEF domain
FNA65_RS23605	COG3238	Protein conserved in bacteria
FNA65_RS23610	COG1247	-acetyltransferase
FNA65_RS23615	COG2130	NADP-dependent
FNA65_RS23630	COG4772	TonB-dependent receptor
FNA65_RS23635	COG3391	amine dehydrogenase activity
FNA65_RS23640	COG1113	amino acid transport
FNA65_RS23645	COG0625	glutathione transferase activity
FNA65_RS23665	COG3209	COG3209 Rhs family protein
FNA65_RS23695	COG0437	4 iron, 4 sulfur cluster binding
FNA65_RS23700	COG2864	formate dehydrogenase
FNA65_RS23705	COG3093	addiction module antidote protein HigA
FNA65_RS23730	COG1764	response to oxidative stress
FNA65_RS23735	COG4608	Belongs to the ABC transporter superfamily
FNA65_RS23740	COG0444	Belongs to the ABC transporter superfamily
FNA65_RS23760	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FNA65_RS23765	COG2199	diguanylate cyclase activity
FNA65_RS23765	COG2202	Pas domain
FNA65_RS23765	COG2200	EAL domain
FNA65_RS23775	COG1649	PFAM Uncharacterised BCR, COG1649
FNA65_RS23780	COG0531	amino acid
FNA65_RS23785	COG0076	glutamate decarboxylase activity
FNA65_RS23790	COG0612	Peptidase, M16
FNA65_RS23795	COG4771	TonB-dependent receptor
FNA65_RS23800	COG4178	(ABC) transporter
FNA65_RS23815	COG2207	Transcriptional regulator
FNA65_RS23825	COG0243	molybdopterin cofactor binding
FNA65_RS23840	COG3550	peptidyl-serine autophosphorylation
FNA65_RS23880	COG0243	molybdopterin cofactor binding
FNA65_RS23895	COG3302	dmso reductase anchor subunit
FNA65_RS23900	COG3381	protein complex oligomerization
FNA65_RS23910	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNA65_RS23915	COG1940	carbohydrate kinase activity
FNA65_RS23920	COG0583	DNA-binding transcription factor activity
FNA65_RS23940	COG3591	Belongs to the peptidase S1B family
FNA65_RS23945	COG3591	Belongs to the peptidase S1B family
FNA65_RS23965	COG0628	permease
FNA65_RS23970	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FNA65_RS23975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FNA65_RS23985	COG0531	amino acid
FNA65_RS23995	COG3136	membrane protein required for alginate biosynthesis
FNA65_RS24000	COG0745	RESPONSE REGULATOR receiver
FNA65_RS24005	COG2205	protein histidine kinase activity
FNA65_RS24015	COG0114	fumarate hydratase activity
FNA65_RS24020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FNA65_RS24020	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FNA65_RS24025	COG1482	cell wall glycoprotein biosynthetic process
FNA65_RS24030	COG5339	Protein conserved in bacteria
FNA65_RS24045	COG3250	beta-galactosidase activity
FNA65_RS24050	COG1309	transcriptional regulator
FNA65_RS24065	COG1609	Transcriptional regulator
FNA65_RS24075	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FNA65_RS24085	COG0673	inositol 2-dehydrogenase activity
FNA65_RS24125	COG4659	FMN binding
FNA65_RS24135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FNA65_RS24140	COG3104	oligopeptide transport
FNA65_RS24145	COG0625	glutathione transferase activity
FNA65_RS24150	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FNA65_RS24170	COG3895	Periplasmic Protein
FNA65_RS24180	COG3133	Outer membrane lipoprotein
FNA65_RS24195	COG1566	PFAM secretion protein HlyD family protein
FNA65_RS24205	COG2032	superoxide dismutase activity
FNA65_RS24210	COG4989	oxidoreductase activity
FNA65_RS24215	COG3313	Fe-S protein
FNA65_RS24220	COG1309	transcriptional regulator
FNA65_RS24225	COG1902	pentaerythritol trinitrate reductase activity
FNA65_RS24230	COG0346	lactoylglutathione lyase activity
FNA65_RS24255	COG4372	Transposase
FNA65_RS24265	COG3547	Transposase (IS116 IS110 IS902 family)
FNA65_RS24275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FNA65_RS24280	COG0791	NLP P60 protein
FNA65_RS24285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNA65_RS24290	COG2814	Major facilitator Superfamily
FNA65_RS24305	COG0583	DNA-binding transcription factor activity
FNA65_RS24310	COG2814	Major facilitator Superfamily
FNA65_RS24315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNA65_RS24320	COG0307	riboflavin synthase, alpha
FNA65_RS24330	COG3468	outer membrane autotransporter barrel domain protein
FNA65_RS24355	COG4372	Transposase
FNA65_RS24360	COG3436	PFAM IS66 Orf2 family protein
FNA65_RS24380	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FNA65_RS24385	COG0437	4 iron, 4 sulfur cluster binding
FNA65_RS24410	COG0469	pyruvate kinase activity
FNA65_RS24415	COG4238	major outer membrane lipoprotein
FNA65_RS24435	COG0719	Fe-S assembly protein
FNA65_RS24440	COG0396	ATPase activity
FNA65_RS24450	COG0316	Belongs to the HesB IscA family
FNA65_RS24460	COG2050	protein possibly involved in aromatic compounds catabolism
FNA65_RS24465	COG0277	FAD linked oxidase domain protein
FNA65_RS24465	COG0247	lactate metabolic process
FNA65_RS24470	COG0628	permease
FNA65_RS24495	COG2271	Major facilitator Superfamily
FNA65_RS24515	COG1960	acyl-CoA dehydrogenase activity
FNA65_RS24520	COG2207	Transcriptional regulator
FNA65_RS24520	COG1917	Cupin 2, conserved barrel domain protein
FNA65_RS24525	COG2086	electron transfer activity
FNA65_RS24530	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FNA65_RS24535	COG0644	oxidoreductase
FNA65_RS24540	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FNA65_RS24545	COG0318	PFAM AMP-dependent synthetase and ligase
FNA65_RS24550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNA65_RS24550	COG0574	Belongs to the PEP-utilizing enzyme family
FNA65_RS24565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FNA65_RS24570	COG4256	Hemin uptake protein
FNA65_RS24585	COG0791	NLP P60 protein
FNA65_RS24775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs