locus-tag	class	description
SDY_0002	COG0460	homoserine dehydrogenase
SDY_0002	COG0527	aspartate kinase activity
SDY_0004	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SDY_0009	COG0521	Mo-molybdopterin cofactor biosynthetic process
SDY_0010	COG1584	GPR1 FUN34 yaaH family protein
SDY_0011	COG4735	regulation of single-species biofilm formation
SDY_0019	COG0583	DNA-binding transcription factor activity
SDY_0025	COG1049	propionate catabolic process, 2-methylcitrate cycle
SDY_0030	COG2132	Multicopper oxidase
SDY_0034	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SDY_0035	COG0288	reversible hydration of carbon dioxide
SDY_0036	COG1131	(ABC) transporter
SDY_0037	COG0842	Transport permease protein
SDY_0038	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_0042	COG5464	transposase or invertase
SDY_0047	COG0196	riboflavin kinase activity
SDY_0050	COG1047	Peptidyl-prolyl cis-trans
SDY_0054	COG0505	Belongs to the CarA family
SDY_0055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SDY_0066	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SDY_0071	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SDY_0080	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SDY_0081	COG1357	PFAM Pentapeptide repeats (8 copies)
SDY_0082	COG0564	pseudouridine synthase activity
SDY_0088	COG0235	Class ii aldolase
SDY_0092	COG0586	Pfam SNARE associated Golgi protein
SDY_0094	COG1178	ABC-type Fe3 transport system permease component
SDY_0095	COG4143	(ABC) transporter
SDY_0104	COG0583	DNA-binding transcription factor activity
SDY_0107	COG0028	Belongs to the TPP enzyme family
SDY_0108	COG0440	acetolactate synthase activity
SDY_0110	COG1609	Transcriptional regulator
SDY_0113	COG3116	cell division
SDY_0114	COG0768	penicillin binding
SDY_0115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SDY_0116	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SDY_0119	COG0772	Belongs to the SEDS family
SDY_0122	COG1181	Belongs to the D-alanine--D-alanine ligase family
SDY_0124	COG0849	cell division
SDY_0125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SDY_0129	COG0494	nUDIX hydrolase
SDY_0133	COG0237	dephospho-CoA kinase activity
SDY_0138	COG4969	Belongs to the N-Me-Phe pilin family
SDY_0139	COG0157	Belongs to the NadC ModD family
SDY_0140	COG3023	N-Acetylmuramoyl-L-alanine amidase
SDY_0141	COG3725	Membrane protein required for beta-lactamase induction
SDY_0142	COG1113	amino acid transport
SDY_0143	COG2186	Transcriptional regulator
SDY_0144	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SDY_0145	COG0508	dehydrogenase complex catalyzes the overall conversion of
SDY_0146	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SDY_0151	COG3188	usher protein
SDY_0158	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SDY_0159	COG0617	tRNA 3'-terminal CCA addition
SDY_0160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SDY_0161	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SDY_0163	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SDY_0165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDY_0166	COG4774	siderophore transport
SDY_0167	COG1120	ATPase activity
SDY_0168	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SDY_0169	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDY_0173	COG2860	membrane
SDY_0174	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SDY_0178	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SDY_0184	COG0024	Methionine aminopeptidase
SDY_0189	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SDY_0190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SDY_0191	COG0575	Belongs to the CDS family
SDY_0192	COG0750	zinc metalloprotease
SDY_0194	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
SDY_0195	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SDY_0200	COG0587	DNA-directed DNA polymerase activity
SDY_0205	COG0346	lactoylglutathione lyase activity
SDY_0206	COG0037	tRNA processing
SDY_0207	COG4568	rho-dependent transcription termination
SDY_0209	COG4681	YaeQ
SDY_0210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SDY_0211	COG3015	lipoprotein NlpE involved in copper resistance
SDY_0212	COG0791	NLP P60 protein
SDY_0214	COG1720	tRNA m6t6A37 methyltransferase activity
SDY_0216	COG1464	Belongs to the NlpA lipoprotein family
SDY_0217	COG2011	ABC-type metal ion transport system permease component
SDY_0219	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SDY_0226	COG0656	L-ascorbic acid biosynthetic process
SDY_0227	COG0583	DNA-binding transcription factor activity
SDY_0230	COG1388	LysM domain
SDY_0230	COG0741	lytic transglycosylase activity
SDY_0232	COG2226	methyltransferase
SDY_0234	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDY_0245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SDY_0249	COG0121	glutamine amidotransferase
SDY_0250	COG3034	peptidoglycan biosynthetic process
SDY_0251	COG3041	Addiction module toxin RelE StbE family
SDY_0252	COG3077	Addiction module antitoxin, RelB DinJ family
SDY_0253	COG0791	NLP P60 protein
SDY_0254	COG1943	Transposase
SDY_0256	COG3121	Chaperone
SDY_0266	COG1215	transferase activity, transferring glycosyl groups
SDY_0268	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SDY_0269	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SDY_0274	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SDY_0275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SDY_0277	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SDY_0280	COG2501	S4 domain
SDY_0287	COG0824	Thioesterase
SDY_0290	COG1555	photosystem II stabilization
SDY_0291	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SDY_0292	COG0776	regulation of translation
SDY_0298	COG0271	Belongs to the BolA IbaG family
SDY_0299	COG3056	Lipoprotein
SDY_0300	COG2223	nitrite transmembrane transporter activity
SDY_0303	COG2814	Major facilitator Superfamily
SDY_0305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SDY_0306	COG0693	protein deglycase activity
SDY_0309	COG0142	geranyltranstransferase activity
SDY_0311	COG0667	Aldo Keto reductase
SDY_0316	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SDY_0317	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SDY_0320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SDY_0320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SDY_0322	COG4238	major outer membrane lipoprotein
SDY_0323	COG3248	Nucleoside-binding outer membrane protein
SDY_0324	COG1403	HNH endonuclease
SDY_0325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SDY_0326	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SDY_0327	COG1862	Preprotein translocase
SDY_0334	COG0366	Alpha amylase catalytic
SDY_0335	COG1113	amino acid transport
SDY_0336	COG1114	Component of the transport system for branched-chain amino acids
SDY_0340	COG3385	transposase activity
SDY_0341	COG0419	ATPase involved in DNA repair
SDY_0345	COG1940	carbohydrate kinase activity
SDY_0353	COG4126	flavin adenine dinucleotide binding
SDY_0356	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SDY_0358	COG3706	GGDEF domain
SDY_0365	COG1181	Belongs to the D-alanine--D-alanine ligase family
SDY_0369	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
SDY_0370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SDY_0371	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SDY_0373	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SDY_0376	COG2223	nitrite transmembrane transporter activity
SDY_0379	COG1609	Transcriptional regulator
SDY_0384	COG1522	sequence-specific DNA binding
SDY_0385	COG1132	(ABC) transporter
SDY_0386	COG1132	(ABC) transporter
SDY_0387	COG0347	Belongs to the P(II) protein family
SDY_0388	COG0004	ammonium transporteR
SDY_0389	COG1946	Acyl-CoA thioesterase
SDY_0391	COG3695	enzyme binding
SDY_0392	COG5507	3-demethylubiquinone-9 3-methyltransferase
SDY_0393	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SDY_0395	COG3960	tartronate-semialdehyde synthase activity
SDY_0396	COG1414	Transcriptional regulator
SDY_0398	COG0583	DNA-binding transcription factor activity
SDY_0400	COG2801	Transposase and inactivated derivatives
SDY_0404	COG2755	lipolytic protein G-D-S-L family
SDY_0405	COG4181	ATPase activity
SDY_0406	COG0300	oxidoreductase activity
SDY_0407	COG3118	belongs to the thioredoxin family
SDY_0408	COG0390	transport system, permease component
SDY_0409	COG4619	ABC transporter
SDY_0410	COG0330	HflC and HflK could
SDY_0411	COG1585	Membrane protein implicated in regulation of membrane protease activity
SDY_0415	COG0789	Transcriptional regulator
SDY_0432	COG0531	amino acid
SDY_0434	COG2217	Heavy metal translocating P-type atpase
SDY_0435	COG3093	addiction module antidote protein HigA
SDY_0436	COG3735	TraB family
SDY_0437	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SDY_0438	COG0737	Belongs to the 5'-nucleotidase family
SDY_0440	COG3385	transposase activity
SDY_0441	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SDY_0441	COG4651	solute:proton antiporter activity
SDY_0442	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDY_0449	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SDY_0451	COG2832	Protein of unknown function (DUF454)
SDY_0452	COG3923	Primosomal replication protein n
SDY_0454	COG1196	nuclear chromosome segregation
SDY_0454	COG3264	Mechanosensitive ion channel
SDY_0455	COG1309	transcriptional regulator
SDY_0456	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDY_0457	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SDY_0460	COG0110	maltose O-acetyltransferase activity
SDY_0462	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SDY_0480	COG2195	Cleaves the N-terminal amino acid of tripeptides
SDY_0481	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SDY_0482	COG1690	Belongs to the RtcB family
SDY_0485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SDY_0488	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SDY_0489	COG1113	amino acid transport
SDY_0490	COG0668	transmembrane transport
SDY_0491	COG0778	Nitroreductase
SDY_0492	COG2315	Protein conserved in bacteria
SDY_0498	COG3468	outer membrane autotransporter barrel domain protein
SDY_0501	COG0113	porphobilinogen synthase activity
SDY_0502	COG2175	clavaminate synthase activity
SDY_0503	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SDY_0505	COG4521	taurine ABC transporter
SDY_0511	COG2977	Belongs to the P-Pant transferase superfamily
SDY_0512	COG4771	TonB-dependent receptor
SDY_0513	COG2382	esterase
SDY_0514	COG3251	PFAM MbtH domain protein
SDY_0515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SDY_0515	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SDY_0518	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
SDY_0519	COG1120	ATPase activity
SDY_0520	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDY_0521	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDY_0523	COG4592	Periplasmic binding protein
SDY_0524	COG1169	isochorismate synthase
SDY_0525	COG1021	2,3-dihydroxybenzoate-AMP ligase
SDY_0526	COG1535	isochorismatase
SDY_0526	COG3433	isochorismatase activity
SDY_0527	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_0528	COG2050	protein possibly involved in aromatic compounds catabolism
SDY_0530	COG2879	small protein
SDY_0531	COG0371	Dehydrogenase
SDY_0534	COG3969	phosphoadenosine phosphosulfate
SDY_0537	COG3969	phosphoadenosine phosphosulfate
SDY_0540	COG0450	alkyl hydroperoxide reductase
SDY_0541	COG3634	alkyl hydroperoxide reductase activity
SDY_0542	COG0589	response to stress
SDY_0549	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SDY_0551	COG0583	DNA-binding transcription factor activity
SDY_0554	COG1686	Belongs to the peptidase S11 family
SDY_0555	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SDY_0556	COG0772	Belongs to the SEDS family
SDY_0557	COG0768	penicillin binding
SDY_0559	COG0799	negative regulation of ribosome biogenesis
SDY_0562	COG1466	dna polymerase III delta subunit
SDY_0567	COG2888	peptidyl-tyrosine sulfation
SDY_0568	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SDY_0588	COG0765	amino acid transport
SDY_0592	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDY_0593	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SDY_0594	COG4535	Mg2 and Co2 transporter CorC
SDY_0596	COG1702	phosphate starvation-inducible protein PhoH
SDY_0598	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SDY_0608	COG0367	asparagine synthase
SDY_0609	COG0647	UMP catabolic process
SDY_0610	COG1846	Transcriptional regulator
SDY_0610	COG1940	carbohydrate kinase activity
SDY_0611	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SDY_0613	COG2190	(PTS) system
SDY_0613	COG1263	PTS System
SDY_0613	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDY_0623	COG0735	belongs to the Fur family
SDY_0624	COG0716	FMN binding
SDY_0626	COG0596	Alpha beta hydrolase
SDY_0628	COG0033	Phosphoglucomutase
SDY_0629	COG0745	RESPONSE REGULATOR receiver
SDY_0636	COG3209	COG3209 Rhs family protein
SDY_0642	COG3272	Protein of unknown function (DUF1722)
SDY_0643	COG0415	Belongs to the DNA photolyase family
SDY_0645	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SDY_0646	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SDY_0647	COG1984	allophanate hydrolase subunit 2
SDY_0650	COG3180	Ammonia monooxygenase
SDY_0651	COG3539	Fimbrial protein
SDY_0652	COG3121	Chaperone
SDY_0655	COG3539	Fimbrial protein
SDY_0658	COG0372	Belongs to the citrate synthase family
SDY_0659	COG2009	succinate dehydrogenase
SDY_0660	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
SDY_0661	COG1053	succinate dehydrogenase
SDY_0662	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SDY_0664	COG0567	Dehydrogenase, E1 component
SDY_0665	COG0508	dehydrogenase complex catalyzes the overall conversion of
SDY_0667	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SDY_0673	COG3799	methylaspartate ammonia-lyase activity
SDY_0676	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SDY_0680	COG1271	oxidase subunit
SDY_0681	COG1294	oxidase, subunit
SDY_0682	COG4890	Cyd operon protein YbgT
SDY_0683	COG3790	cyd operon protein YbgE
SDY_0684	COG0824	Thioesterase
SDY_0685	COG0811	peptide transport
SDY_0686	COG0848	biopolymer transport protein
SDY_0687	COG3064	Membrane
SDY_0689	COG2885	chlorophyll binding
SDY_0690	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
SDY_0695	COG3201	nicotinamide mononucleotide transporter
SDY_0696	COG1230	cation diffusion facilitator family transporter
SDY_0701	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SDY_0703	COG2017	converts alpha-aldose to the beta-anomer
SDY_0705	COG1085	galactose-1-phosphate uridylyltransferase
SDY_0706	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SDY_0707	COG1119	ATPase activity
SDY_0708	COG2005	Transcriptional regulator
SDY_0708	COG3585	molybdate ion transport
SDY_0710	COG0725	ABC transporter, periplasmic molybdate-binding protein
SDY_0711	COG4149	molybdate abc transporter
SDY_0726	COG1783	phage Terminase large subunit
SDY_0738	COG1177	transmembrane transport
SDY_0739	COG1176	ABC-type spermidine putrescine transport system, permease component I
SDY_0740	COG3842	ATPase activity
SDY_0741	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SDY_0744	COG0778	Nitroreductase
SDY_0746	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SDY_0750	COG3226	Transcriptional regulator
SDY_0751	COG0738	Major facilitator superfamily
SDY_0752	COG0561	phosphatase activity
SDY_0759	COG1446	asparaginase
SDY_0760	COG0303	'Molybdopterin
SDY_0761	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SDY_0762	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SDY_0763	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDY_0764	COG1882	Formate acetyltransferase
SDY_0765	COG0561	phosphatase activity
SDY_0776	COG0488	(ABC) transporter
SDY_0777	COG1376	ErfK ybiS ycfS ynhG family protein
SDY_0779	COG1321	iron dependent repressor
SDY_0780	COG2194	sulfuric ester hydrolase activity
SDY_0781	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
SDY_0785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDY_0786	COG0765	amino acid transport
SDY_0787	COG1126	abc transporter atp-binding protein
SDY_0793	COG3385	transposase activity
SDY_0794	COG4774	siderophore transport
SDY_0796	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SDY_0798	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SDY_0799	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SDY_0800	COG1199	ATP-dependent helicase activity
SDY_0806	COG0513	Belongs to the DEAD box helicase family
SDY_0807	COG1309	transcriptional regulator
SDY_0809	COG1131	(ABC) transporter
SDY_0810	COG0842	Transport permease protein
SDY_0811	COG0842	Transport permease protein
SDY_0813	COG3568	Endonuclease Exonuclease Phosphatase
SDY_0814	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SDY_0815	COG0392	lysyltransferase activity
SDY_0817	COG0670	Belongs to the BI1 family
SDY_0821	COG0314	molybdopterin synthase activity
SDY_0822	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SDY_0824	COG0521	Mo-molybdopterin cofactor biosynthetic process
SDY_0826	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SDY_0828	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SDY_0829	COG2226	methyltransferase
SDY_0832	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SDY_0833	COG1881	PFAM PEBP family protein
SDY_0838	COG0625	glutathione transferase activity
SDY_0841	COG1686	Belongs to the peptidase S11 family
SDY_0842	COG1349	DNA-binding transcription factor activity
SDY_0843	COG0671	phosphoesterase, PA-phosphatase related
SDY_0852	COG2373	Large extracellular alpha-helical protein
SDY_0853	COG5445	Predicted secreted protein (DUF2300)
SDY_0856	COG0784	Response regulator, receiver
SDY_0856	COG2205	protein histidine kinase activity
SDY_0857	COG2197	response regulator
SDY_0858	COG0642	Histidine kinase
SDY_0858	COG2198	Histidine kinase
SDY_0861	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SDY_0862	COG1477	protein flavinylation
SDY_0863	COG2169	Transcriptional regulator
SDY_0863	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SDY_0864	COG3145	DNA-N1-methyladenine dioxygenase activity
SDY_0865	COG4615	Cyclic peptide transporter
SDY_0870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SDY_0870	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
SDY_0871	COG3062	negative regulation of establishment of protein localization
SDY_0873	COG0437	4 iron, 4 sulfur cluster binding
SDY_0874	COG0348	domain, Protein
SDY_0875	COG3043	anaerobic respiration
SDY_0876	COG3005	denitrification pathway
SDY_0878	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SDY_0879	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SDY_0880	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SDY_0882	COG1138	Cytochrome C-type biogenesis protein
SDY_0883	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDY_0884	COG4235	cytochrome complex assembly
SDY_0884	COG3088	subunit of a heme lyase
SDY_0885	COG2197	response regulator
SDY_0889	COG3468	outer membrane autotransporter barrel domain protein
SDY_0891	COG3083	sulfuric ester hydrolase activity
SDY_0895	COG1061	Type III restriction enzyme res subunit
SDY_0896	COG1187	pseudouridine synthase activity
SDY_0897	COG2814	Major facilitator Superfamily
SDY_0899	COG4172	Belongs to the ABC transporter superfamily
SDY_0900	COG4239	(ABC) transporter, permease
SDY_0901	COG4174	ABC transporter (Permease)
SDY_0902	COG4166	transmembrane transport
SDY_0903	COG2200	EAL domain
SDY_0904	COG0791	NLP P60 protein
SDY_0905	COG0671	phosphoesterase, PA-phosphatase related
SDY_0906	COG0523	cobalamin synthesis protein
SDY_0909	COG2814	Major facilitator Superfamily
SDY_0912	COG3188	usher protein
SDY_0914	COG3539	Fimbrial protein
SDY_0915	COG3539	Fimbrial protein
SDY_0916	COG3539	Fimbrial protein
SDY_0917	COG3121	Chaperone
SDY_0920	COG0633	Ferredoxin
SDY_0920	COG3217	Mosc domain protein beta barrel domain protein
SDY_0922	COG0488	(ABC) transporter
SDY_0923	COG2995	paraquat-inducible protein a
SDY_0924	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SDY_0924	COG3008	intermembrane lipid transfer
SDY_0925	COG3009	Protein conserved in bacteria
SDY_0926	COG3130	regulation of translation
SDY_0934	COG3070	regulator of competence-specific genes
SDY_0935	COG1289	transmembrane transporter activity
SDY_0936	COG3304	Inner membrane component domain
SDY_0937	COG0210	DNA helicase
SDY_0940	COG1832	CoA-binding protein
SDY_0943	COG1254	Belongs to the acylphosphatase family
SDY_0945	COG0670	Belongs to the BI1 family
SDY_0947	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SDY_0949	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
SDY_0950	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SDY_0951	COG1999	signal sequence binding
SDY_0953	COG1271	oxidase subunit
SDY_0954	COG1294	oxidase, subunit
SDY_0957	COG3206	protein involved in exopolysaccharide biosynthesis
SDY_0957	COG0489	protein tyrosine kinase activity
SDY_0958	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SDY_0959	COG1596	polysaccharide export
SDY_0960	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SDY_0964	COG1278	Cold shock
SDY_0966	COG0348	domain, Protein
SDY_0968	COG1879	ABC-type sugar transport system periplasmic component
SDY_0969	COG0745	RESPONSE REGULATOR receiver
SDY_0980a	COG3729	General stress protein
SDY_0981	COG2233	PERMEase
SDY_0988	COG1309	transcriptional regulator
SDY_0990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SDY_0996	COG2197	response regulator
SDY_0999	COG1462	curli production assembly transport component CsgG
SDY_1002	COG3381	protein complex oligomerization
SDY_1013	COG2003	Belongs to the UPF0758 family
SDY_1023	COG2819	hydrolase of the alpha beta superfamily
SDY_1024	COG2382	esterase
SDY_1033	COG3443	Belongs to the bacterial solute-binding protein 9 family
SDY_1038	COG2351	hydroxyisourate hydrolase activity
SDY_1039	COG0745	RESPONSE REGULATOR receiver
SDY_1045	COG0270	DNA (cytosine-5-)-methyltransferase activity
SDY_1046	COG3727	T/G mismatch-specific endonuclease activity
SDY_1047	COG0697	spore germination
SDY_1048	COG2354	Protein conserved in bacteria
SDY_1049	COG5475	Uncharacterized small protein (DUF2158)
SDY_1060	COG0500	methyltransferase
SDY_1065	COG5301	cellulose 1,4-beta-cellobiosidase activity
SDY_1074	COG2373	Large extracellular alpha-helical protein
SDY_1074	COG1388	LysM domain
SDY_1074	COG4932	domain protein
SDY_1075	COG4932	domain protein
SDY_1075	COG1388	LysM domain
SDY_1075	COG2373	Large extracellular alpha-helical protein
SDY_1076	COG1470	cell adhesion involved in biofilm formation
SDY_1076	COG1388	LysM domain
SDY_1077	COG4932	domain protein
SDY_1077	COG2373	Large extracellular alpha-helical protein
SDY_1077	COG1388	LysM domain
SDY_1084	COG2135	peptidase activity
SDY_1085	COG0425	Belongs to the sulfur carrier protein TusA family
SDY_1086	COG2391	methyltransferase activity
SDY_1088	COG0366	Alpha amylase catalytic
SDY_1090	COG1516	flagellar protein fliS
SDY_1091	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SDY_1095	COG1191	sigma factor activity
SDY_1097	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDY_1099	COG0765	amino acid transport
SDY_1100	COG1126	abc transporter atp-binding protein
SDY_1104	COG2197	response regulator
SDY_1110	COG3012	SEC-C Motif Domain Protein
SDY_1110	COG3318	Belongs to the UPF0149 family
SDY_1111	COG0814	amino acid
SDY_1113	COG1528	Iron-storage protein
SDY_1116	COG1528	Iron-storage protein
SDY_1120	COG1879	ABC-type sugar transport system periplasmic component
SDY_1122	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDY_1127	COG2372	response to copper ion
SDY_1129	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SDY_1130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDY_1131	COG1770	oligopeptidase
SDY_1132	COG2979	Protein of unknown function (DUF533)
SDY_1134	COG3141	response to X-ray
SDY_1136	COG0800	Aldolase
SDY_1137	COG0129	dihydroxy-acid dehydratase activity
SDY_1138	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SDY_1141	COG0469	pyruvate kinase activity
SDY_1142	COG1560	Kdo2-lipid A biosynthetic process
SDY_1143	COG0739	heme binding
SDY_1144	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
SDY_1146	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SDY_1152	COG0494	nUDIX hydrolase
SDY_1154	COG1335	isochorismatase
SDY_1155	COG3547	Transposase (IS116 IS110 IS902 family)
SDY_1167	COG1801	Protein of unknown function DUF72
SDY_1168	COG3788	relative of glutathione S-transferase, MAPEG superfamily
SDY_1171	COG0243	molybdopterin cofactor binding
SDY_1179	COG3102	Protein conserved in bacteria
SDY_1184	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SDY_1189	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SDY_1192	COG0589	response to stress
SDY_1194	COG1877	trehalose-phosphatase activity
SDY_1202	COG3468	outer membrane autotransporter barrel domain protein
SDY_1202	COG3468	outer membrane autotransporter barrel domain protein
SDY_1204	COG3468	outer membrane autotransporter barrel domain protein
SDY_1206	COG2894	cell division
SDY_1212	COG0179	Fumarylacetoacetate (FAA) hydrolase
SDY_1220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SDY_1221	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SDY_1222	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SDY_1225	COG2719	SpoVR family
SDY_1232	COG1619	proteins homologs of microcin C7 resistance protein MccF
SDY_1233	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
SDY_1236	COG0157	Belongs to the NadC ModD family
SDY_1239	COG0500	methyltransferase
SDY_1240	COG1120	ATPase activity
SDY_1241	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDY_1248	COG1461	Dihydroxyacetone kinase
SDY_1249	COG3284	Transcriptional regulator
SDY_1252	COG0012	GTP binding
SDY_1255	COG0659	secondary active sulfate transmembrane transporter activity
SDY_1256	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SDY_1262	COG3094	Invasion gene expression up-regulator, SirB
SDY_1263	COG2912	Transglutaminase-like superfamily
SDY_1266	COG0387	Pfam Sodium calcium exchanger
SDY_1269	COG4572	Cation transport regulator
SDY_1270	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
SDY_1271	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
SDY_1275	COG2197	response regulator
SDY_1276	COG3850	Histidine kinase
SDY_1278	COG2223	nitrite transmembrane transporter activity
SDY_1279	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SDY_1280	COG1140	nitrate reductase beta subunit
SDY_1281	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SDY_1282	COG2181	nitrate reductase activity
SDY_1284	COG0788	formyltetrahydrofolate deformylase activity
SDY_1287	COG0745	RESPONSE REGULATOR receiver
SDY_1288	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SDY_1292	COG3385	transposase activity
SDY_1295	COG1454	alcohol dehydrogenase
SDY_1295	COG1012	belongs to the aldehyde dehydrogenase family
SDY_1301	COG4166	transmembrane transport
SDY_1302	COG0601	transmembrane transport
SDY_1303	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SDY_1304	COG0444	Belongs to the ABC transporter superfamily
SDY_1305	COG4608	Belongs to the ABC transporter superfamily
SDY_1308	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SDY_1309	COG2350	Protein conserved in bacteria
SDY_1316	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
SDY_1317	COG1607	acyl-coa hydrolase
SDY_1320	COG3047	cAMP biosynthetic process
SDY_1321	COG3685	Protein conserved in bacteria
SDY_1330	COG0135	phosphoribosylanthranilate isomerase activity
SDY_1330	COG0134	indole-3-glycerol-phosphate synthase activity
SDY_1331	COG0512	Glutamine amidotransferase of anthranilate synthase
SDY_1331	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SDY_1332	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SDY_1334	COG0613	PHP domain protein
SDY_1335	COG0009	L-threonylcarbamoyladenylate synthase
SDY_1338	COG4907	membrane protein (DUF2207)
SDY_1339	COG1187	pseudouridine synthase activity
SDY_1340	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SDY_1341	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_1342	COG0616	signal peptide processing
SDY_1344	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SDY_1345	COG0583	DNA-binding transcription factor activity
SDY_1354	COG0671	phosphoesterase, PA-phosphatase related
SDY_1355	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
SDY_1356	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
SDY_1358	COG0023	Translation Initiation Factor
SDY_1361	COG1349	DNA-binding transcription factor activity
SDY_1368	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SDY_1372	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SDY_1375	COG2814	Major facilitator Superfamily
SDY_1376	COG3547	Transposase (IS116 IS110 IS902 family)
SDY_1377	COG4172	Belongs to the ABC transporter superfamily
SDY_1378	COG4172	Belongs to the ABC transporter superfamily
SDY_1379	COG4171	peptide transport system, permease
SDY_1385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDY_1394	COG3772	lysozyme
SDY_1398	COG1609	Transcriptional regulator
SDY_1399	COG3106	COG3106 Predicted ATPase
SDY_1401	COG3283	Transcriptional regulator of aromatic amino acids metabolism
SDY_1402	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SDY_1403	COG4948	Mandelate Racemase Muconate Lactonizing
SDY_1404	COG2866	Carboxypeptidase
SDY_1408	COG0583	DNA-binding transcription factor activity
SDY_1409	COG4166	transmembrane transport
SDY_1410	COG0668	transmembrane transport
SDY_1413	COG0589	response to stress
SDY_1416	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SDY_1419	COG2840	Smr protein MutS2
SDY_1420	COG3706	GGDEF domain
SDY_1423	COG3706	GGDEF domain
SDY_1427	COG0582	viral genome integration into host DNA
SDY_1434	COG1403	HNH endonuclease
SDY_1435	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
SDY_1436	COG0484	heat shock protein binding
SDY_1454	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SDY_1455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SDY_1456	COG1121	(ABC) transporter
SDY_1458	COG0589	response to stress
SDY_1461	COG0674	pyruvate-flavodoxin oxidoreductase activity
SDY_1461	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SDY_1461	COG1013	pyruvate-flavodoxin oxidoreductase activity
SDY_1461	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SDY_1462	COG3042	response to heat
SDY_1464	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SDY_1465	COG2911	Protein conserved in bacteria
SDY_1472	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SDY_1477	COG2271	Major facilitator Superfamily
SDY_1483	COG0738	Major facilitator superfamily
SDY_1485	COG3713	MltA-interacting MipA family protein
SDY_1486	COG0656	L-ascorbic acid biosynthetic process
SDY_1487	COG0676	glucose-6-phosphate 1-epimerase activity
SDY_1488	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SDY_1490	COG3139	Protein of unknown function (DUF1315)
SDY_1491	COG1063	alcohol dehydrogenase
SDY_1492	COG2271	Major facilitator Superfamily
SDY_1493	COG1063	alcohol dehydrogenase
SDY_1495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDY_1498	COG1349	DNA-binding transcription factor activity
SDY_1499	COG2814	Major facilitator Superfamily
SDY_1505	COG1335	isochorismatase
SDY_1506	COG0252	asparaginase activity
SDY_1507	COG0616	signal peptide processing
SDY_1508	COG0778	Nitroreductase
SDY_1509	COG0709	Synthesizes selenophosphate from selenide and ATP
SDY_1510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SDY_1514	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SDY_1516	COG0494	nUDIX hydrolase
SDY_1519	COG4136	ATPase activity
SDY_1523	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SDY_1524	COG0398	Pfam SNARE associated Golgi protein
SDY_1526	COG0398	Pfam SNARE associated Golgi protein
SDY_1527	COG0708	Exodeoxyribonuclease III
SDY_1534	COG3678	ATP-independent chaperone mediated protein folding
SDY_1539	COG0322	excinuclease ABC activity
SDY_1541	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SDY_1546	COG3136	membrane protein required for alginate biosynthesis
SDY_1548	COG0531	amino acid
SDY_1550	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SDY_1551	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SDY_1552	COG0628	permease
SDY_1555	COG3591	Belongs to the peptidase S1B family
SDY_1561	COG0583	DNA-binding transcription factor activity
SDY_1562	COG1940	carbohydrate kinase activity
SDY_1563	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SDY_1566	COG3302	dmso reductase anchor subunit
SDY_1567	COG0437	4 iron, 4 sulfur cluster binding
SDY_1575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SDY_1582	COG0477	Major facilitator Superfamily
SDY_1585	COG1802	Transcriptional regulator
SDY_1586	COG4221	oxidoreductase activity
SDY_1587	COG0339	signal peptide processing
SDY_1588	COG1546	Belongs to the CinA family
SDY_1589	COG3111	PFAM Bacterial OB fold (BOF) protein
SDY_1590	COG3706	GGDEF domain
SDY_1593	COG2814	Major facilitator Superfamily
SDY_1594	COG0697	spore germination
SDY_1596	COG4977	sequence-specific DNA binding
SDY_1597	COG1846	Transcriptional regulator
SDY_1603	COG0697	spore germination
SDY_1605	COG0437	4 iron, 4 sulfur cluster binding
SDY_1606	COG2864	formate dehydrogenase
SDY_1607	COG3093	addiction module antidote protein HigA
SDY_1608	COG1064	alcohol dehydrogenase
SDY_1610	COG1764	response to oxidative stress
SDY_1611	COG4608	Belongs to the ABC transporter superfamily
SDY_1613	COG1649	PFAM Uncharacterised BCR, COG1649
SDY_1614	COG0531	amino acid
SDY_1615	COG0076	glutamate decarboxylase activity
SDY_1618	COG2911	Protein conserved in bacteria
SDY_1618	COG3210	domain, Protein
SDY_1629	COG2199	diguanylate cyclase activity
SDY_1632	COG1012	belongs to the aldehyde dehydrogenase family
SDY_1633	COG0583	DNA-binding transcription factor activity
SDY_1636	COG0531	amino acid
SDY_1638	COG4166	transmembrane transport
SDY_1639	COG4168	peptide transport system, permease
SDY_1647	COG2223	nitrite transmembrane transporter activity
SDY_1651	COG1140	nitrate reductase beta subunit
SDY_1652	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SDY_1653	COG2181	nitrate reductase activity
SDY_1654	COG0384	phenazine biosynthesis protein PhzF
SDY_1655	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SDY_1657	COG3539	Fimbrial protein
SDY_1658	COG0243	molybdopterin cofactor binding
SDY_1660	COG2207	Transcriptional regulator
SDY_1661	COG3119	arylsulfatase activity
SDY_1668	COG4886	Leucine-rich repeat (LRR) protein
SDY_1674	COG2050	protein possibly involved in aromatic compounds catabolism
SDY_1675	COG0247	lactate metabolic process
SDY_1675	COG0277	FAD linked oxidase domain protein
SDY_1676	COG0628	permease
SDY_1682	COG0738	Major facilitator superfamily
SDY_1684	COG2199	diguanylate cyclase activity
SDY_1685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SDY_1688	COG2207	Transcriptional regulator
SDY_1689	COG2807	transmembrane transport
SDY_1690	COG3189	MarR family transcriptional regulator
SDY_1691	COG3042	response to heat
SDY_1692	COG2203	Gaf domain
SDY_1692	COG2199	diguanylate cyclase activity
SDY_1695	COG2261	transglycosylase associated protein
SDY_1697	COG3615	Tellurite resistance protein tehB
SDY_1700	COG0583	DNA-binding transcription factor activity
SDY_1701	COG0473	3-isopropylmalate dehydrogenase activity
SDY_1706	COG4638	Rieske (2fe-2S)
SDY_1707	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SDY_1708	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SDY_1709	COG0318	PFAM AMP-dependent synthetase and ligase
SDY_1710	COG3065	identical protein binding
SDY_1711	COG1214	PFAM Peptidase M22, glycoprotease
SDY_1712	COG1199	ATP-dependent helicase activity
SDY_1713	COG0251	oxidation-reduction process
SDY_1718	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SDY_1720	COG1760	l-serine dehydratase
SDY_1723	COG1802	Transcriptional regulator
SDY_1724	COG2130	NADP-dependent
SDY_1725	COG1247	-acetyltransferase
SDY_1726	COG3238	Protein conserved in bacteria
SDY_1733	COG3842	ATPase activity
SDY_1734	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SDY_1735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SDY_1736	COG1598	PFAM Uncharacterised protein family UPF0150
SDY_1740	COG0826	peptidase U32
SDY_1742	COG1396	sequence-specific DNA binding
SDY_1747	COG0500	methyltransferase
SDY_1748	COG1275	C4-dicarboxylate transporter malic acid transport protein
SDY_1751	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SDY_1752	COG2841	Protein conserved in bacteria
SDY_1757	COG5383	Protein conserved in bacteria
SDY_1758	COG0583	DNA-binding transcription factor activity
SDY_1760	COG0840	transmembrane signaling receptor activity
SDY_1764	COG3038	cytochrome b561
SDY_1774	COG1643	Atp-dependent helicase
SDY_1776	COG0671	phosphoesterase, PA-phosphatase related
SDY_1776	COG2453	phosphatase
SDY_1779	COG2267	carboxylic ester hydrolase activity
SDY_1783	COG1960	acyl-CoA dehydrogenase activity
SDY_1786	COG2207	Transcriptional regulator
SDY_1786	COG1917	Cupin 2, conserved barrel domain protein
SDY_1791	COG0644	oxidoreductase
SDY_1792	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SDY_1794	COG0574	Belongs to the PEP-utilizing enzyme family
SDY_1794	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SDY_1798	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SDY_1799	COG4256	Hemin uptake protein
SDY_1802	COG2200	EAL domain
SDY_1803	COG0791	NLP P60 protein
SDY_1805	COG0386	Belongs to the glutathione peroxidase family
SDY_1816	COG1105	Belongs to the carbohydrate kinase PfkB family
SDY_1818	COG3001	Fructosamine kinase
SDY_1820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDY_1821	COG1988	membrane-bound metal-dependent
SDY_1824	COG0745	RESPONSE REGULATOR receiver
SDY_1825	COG2205	protein histidine kinase activity
SDY_1827	COG0114	fumarate hydratase activity
SDY_1828	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SDY_1828	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SDY_1829	COG1482	cell wall glycoprotein biosynthetic process
SDY_1830	COG5339	Protein conserved in bacteria
SDY_1837	COG1309	transcriptional regulator
SDY_1838	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_1841	COG1609	Transcriptional regulator
SDY_1842	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDY_1842	COG1263	PTS System
SDY_1845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SDY_1847	COG0673	inositol 2-dehydrogenase activity
SDY_1854	COG4659	FMN binding
SDY_1856	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SDY_1857	COG3104	oligopeptide transport
SDY_1858	COG0625	glutathione transferase activity
SDY_1862	COG3895	Periplasmic Protein
SDY_1864	COG3133	Outer membrane lipoprotein
SDY_1867	COG1566	PFAM secretion protein HlyD family protein
SDY_1870	COG2032	superoxide dismutase activity
SDY_1871	COG4989	oxidoreductase activity
SDY_1872	COG1309	transcriptional regulator
SDY_1873	COG3313	Fe-S protein
SDY_1877	COG0346	lactoylglutathione lyase activity
SDY_1880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SDY_1881	COG0791	NLP P60 protein
SDY_1882	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SDY_1883	COG2814	Major facilitator Superfamily
SDY_1885	COG0583	DNA-binding transcription factor activity
SDY_1886	COG2814	Major facilitator Superfamily
SDY_1887	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SDY_1888	COG0307	riboflavin synthase, alpha
SDY_1891	COG3468	outer membrane autotransporter barrel domain protein
SDY_1898	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
SDY_1899	COG0437	4 iron, 4 sulfur cluster binding
SDY_1905	COG0469	pyruvate kinase activity
SDY_1908	COG4238	major outer membrane lipoprotein
SDY_1909	COG1376	ErfK ybiS ycfS ynhG family protein
SDY_1912	COG0719	Fe-S assembly protein
SDY_1913	COG0396	ATPase activity
SDY_1916	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SDY_1928	COG3646	Phage regulatory protein
SDY_1936	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SDY_1938	COG1983	PspC domain protein
SDY_1940	COG1842	Phage shock protein A
SDY_1941	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SDY_1943	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SDY_1945	COG1396	sequence-specific DNA binding
SDY_1945	COG1917	Cupin 2, conserved barrel domain protein
SDY_1948	COG0531	amino acid
SDY_1951	COG0625	glutathione transferase activity
SDY_1952	COG1113	amino acid transport
SDY_1953	COG3391	amine dehydrogenase activity
SDY_1954	COG4772	TonB-dependent receptor
SDY_1957	COG1802	Transcriptional regulator
SDY_1962	COG1253	flavin adenine dinucleotide binding
SDY_1963	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDY_1963	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_1965	COG3716	PTS system mannose fructose sorbose family IID component
SDY_1968	COG2226	methyltransferase
SDY_1975	COG1414	Transcriptional regulator
SDY_1976	COG2814	Major facilitator Superfamily
SDY_1978	COG0793	Belongs to the peptidase S41A family
SDY_1980	COG1956	GAF domain-containing protein
SDY_1981	COG2995	paraquat-inducible protein a
SDY_1982	COG2995	paraquat-inducible protein a
SDY_1984	COG2995	paraquat-inducible protein a
SDY_1985	COG3008	intermembrane lipid transfer
SDY_1989	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SDY_2012	COG0583	DNA-binding transcription factor activity
SDY_2016	COG0538	isocitrate dehydrogenase activity
SDY_2017	COG1187	pseudouridine synthase activity
SDY_2021	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SDY_2023	COG2205	protein histidine kinase activity
SDY_2024	COG2850	peptidyl-arginine hydroxylation
SDY_2027	COG1176	ABC-type spermidine putrescine transport system, permease component I
SDY_2028	COG1177	transmembrane transport
SDY_2029	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SDY_2030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SDY_2032	COG4591	ABC-type transport system involved in lipoprotein release permease component
SDY_2034	COG4591	ABC-type transport system involved in lipoprotein release permease component
SDY_2035	COG4763	Acyl-transferase
SDY_2036	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SDY_2037	COG1376	ErfK ybiS ycfS ynhG family protein
SDY_2037	COG1388	LysM domain
SDY_2039	COG1309	transcriptional regulator
SDY_2040	COG3134	Outer membrane lipoprotein
SDY_2041	COG1252	NADH dehydrogenase
SDY_2045	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
SDY_2046	COG5633	Lipoprotein
SDY_2047	COG0537	adenosine 5'-monophosphoramidase activity
SDY_2048	COG4773	Receptor
SDY_2049	COG1263	PTS System
SDY_2049	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDY_2050	COG0084	hydrolase, TatD family'
SDY_2051	COG0470	DNA polymerase III
SDY_2053	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SDY_2054	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SDY_2055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDY_2057	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_2058	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SDY_2062	COG1399	metal-binding, possibly nucleic acid-binding protein
SDY_2065	COG0564	pseudouridine synthase activity
SDY_2067	COG1530	ribonuclease E activity
SDY_2070	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDY_2070	COG3951	Flagellar rod assembly protein muramidase FlgJ
SDY_2075	COG1749	Flagellar hook protein flgE
SDY_2076	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SDY_2077	COG1558	bacterial-type flagellum-dependent cell motility
SDY_2078	COG1815	bacterial-type flagellum-dependent cell motility
SDY_2080	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
SDY_2081	COG2747	anti-sigma28 factor FlgM
SDY_2083	COG0728	peptidoglycan biosynthetic process
SDY_2084	COG0673	inositol 2-dehydrogenase activity
SDY_2086	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SDY_2089	COG2999	glutathione oxidoreductase activity
SDY_2099	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SDY_2103	COG3677	Transposase
SDY_2105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SDY_2106	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDY_2106	COG1522	sequence-specific DNA binding
SDY_2108	COG2855	membrane
SDY_2109	COG0583	DNA-binding transcription factor activity
SDY_2110	COG0833	amino acid
SDY_2129	COG1609	Transcriptional regulator
SDY_2130	COG1879	ABC-type sugar transport system periplasmic component
SDY_2137	COG4211	Belongs to the binding-protein-dependent transport system permease family
SDY_2140a	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SDY_2140a	COG0167	dihydroorotate dehydrogenase activity
SDY_2143	COG2949	membrane
SDY_2145	COG1346	cytolysis
SDY_2151	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_2152	COG0586	Pfam SNARE associated Golgi protein
SDY_2154	COG1686	Belongs to the peptidase S11 family
SDY_2155	COG0277	FAD linked oxidase domain protein
SDY_2156	COG1472	Belongs to the glycosyl hydrolase 3 family
SDY_2157	COG1732	Glycine betaine
SDY_2160	COG1174	glycine betaine transport
SDY_2162	COG0789	Transcriptional regulator
SDY_2163	COG3275	phosphorelay sensor kinase activity
SDY_2164	COG3279	Response regulator of the LytR AlgR family
SDY_2165	COG4807	Protein conserved in bacteria
SDY_2166	COG4808	Protein conserved in bacteria
SDY_2167	COG4715	Zinc finger, swim domain protein
SDY_2170	COG4715	Zinc finger, swim domain protein
SDY_2180	COG3831	ATPase activity
SDY_2182	COG0489	protein tyrosine kinase activity
SDY_2186	COG0745	RESPONSE REGULATOR receiver
SDY_2187	COG2205	protein histidine kinase activity
SDY_2189	COG3547	Transposase (IS116 IS110 IS902 family)
SDY_2190	COG4245	von Willebrand factor, type A
SDY_2191	COG0631	protein serine/threonine phosphatase activity
SDY_2192	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
SDY_2193	COG0443	Heat shock 70 kDa protein
SDY_2194	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
SDY_2196	COG0572	uridine kinase
SDY_2198	COG2982	Protein involved in outer membrane biogenesis
SDY_2201	COG1253	flavin adenine dinucleotide binding
SDY_2203	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SDY_2204	COG1088	dTDP-glucose 4,6-dehydratase activity
SDY_2205	COG1091	dTDP-4-dehydrorhamnose reductase activity
SDY_2212	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SDY_2213	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SDY_2218	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SDY_2219	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SDY_2219	COG0131	Imidazoleglycerol-phosphate dehydratase
SDY_2223	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SDY_2226	COG0531	amino acid
SDY_2227	COG2391	methyltransferase activity
SDY_2230	COG0425	Belongs to the sulfur carrier protein TusA family
SDY_2231	COG2925	Exonuclease
SDY_2233	COG1686	Belongs to the peptidase S11 family
SDY_2236	COG1289	transmembrane transporter activity
SDY_2240	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
SDY_2243	COG1376	ErfK ybiS ycfS ynhG family protein
SDY_2245	COG0583	DNA-binding transcription factor activity
SDY_2246	COG0583	DNA-binding transcription factor activity
SDY_2248	COG0534	Mate efflux family protein
SDY_2249	COG0534	Mate efflux family protein
SDY_2253	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SDY_2254	COG0477	Major facilitator Superfamily
SDY_2257	COG3609	addiction module antidote protein, CC2985 family
SDY_2259	COG0826	peptidase U32
SDY_2263	COG1063	alcohol dehydrogenase
SDY_2265	COG3414	Phosphotransferase system galactitol-specific IIB component
SDY_2270	COG1830	Aldolase
SDY_2271	COG2211	Major facilitator Superfamily
SDY_2272	COG1397	ADP-ribosylglycohydrolase
SDY_2273	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDY_2274	COG2188	Transcriptional regulator
SDY_2277	COG0351	phosphomethylpyrimidine kinase
SDY_2281	COG5455	response to cobalt ion
SDY_2287	COG3188	usher protein
SDY_2293	COG1560	Kdo2-lipid A biosynthetic process
SDY_2300	COG5645	(Lipo)protein
SDY_2301	COG2943	transferase activity, transferring hexosyl groups
SDY_2304	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SDY_2312	COG3038	cytochrome b561
SDY_2315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDY_2315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDY_2315	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SDY_2316	COG1105	Belongs to the carbohydrate kinase PfkB family
SDY_2317	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_2317	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_2319	COG0431	NADPH-dependent FMN reductase
SDY_2320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SDY_2323	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SDY_2325	COG0308	aminopeptidase N
SDY_2329	COG1448	Aminotransferase
SDY_2330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SDY_2331	COG3108	Peptidase M15
SDY_2332	COG2989	Protein conserved in bacteria
SDY_2335	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
SDY_2337	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SDY_2338	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SDY_2339	COG3173	Aminoglycoside phosphotransferase
SDY_2342	COG3214	Protein conserved in bacteria
SDY_2344	COG1132	(ABC) transporter
SDY_2345	COG2333	competence protein COMEC
SDY_2345	COG0658	competence protein
SDY_2347	COG0539	negative regulation of cytoplasmic translation
SDY_2349	COG0501	Belongs to the peptidase M48B family
SDY_2352	COG3385	transposase activity
SDY_2355	COG2323	membrane
SDY_2357	COG2116	formate transmembrane transporter activity
SDY_2358	COG1882	Formate acetyltransferase
SDY_2359	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDY_2365	COG3302	dmso reductase anchor subunit
SDY_2367	COG0243	molybdopterin cofactor binding
SDY_2369	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SDY_2371	COG1674	ftsk spoiiie
SDY_2371	COG1178	ABC-type Fe3 transport system permease component
SDY_2372	COG1522	sequence-specific DNA binding
SDY_2373	COG0492	ferredoxin-NADP+ reductase activity
SDY_2374	COG4988	ABC transporter
SDY_2375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SDY_2379	COG0542	response to heat
SDY_2381	COG1278	Cold shock
SDY_2383	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDY_2384	COG2990	Protein conserved in bacteria
SDY_2385	COG3593	DNA synthesis involved in DNA repair
SDY_2386	COG1662	PFAM IS1 transposase
SDY_2389	COG2431	L-lysine efflux transmembrane transporter activity
SDY_2391	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SDY_2392	COG0028	Belongs to the TPP enzyme family
SDY_2393	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
SDY_2394	COG0702	epimerase
SDY_2395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SDY_2396	COG3023	N-Acetylmuramoyl-L-alanine amidase
SDY_2404	COG1126	abc transporter atp-binding protein
SDY_2405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDY_2406	COG4215	(ABC) transporter
SDY_2407	COG4160	amino acid transport
SDY_2408	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDY_2420	COG0582	viral genome integration into host DNA
SDY_2421	COG3234	Protein of unknown function (DUF1175)
SDY_2422	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
SDY_2422	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
SDY_2423	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SDY_2428	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SDY_2429	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SDY_2430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SDY_2432	COG2814	Major facilitator Superfamily
SDY_2434	COG0584	glycerophosphoryl diester phosphodiesterase
SDY_2435	COG2271	Major facilitator Superfamily
SDY_2436	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SDY_2438	COG0247	lactate metabolic process
SDY_2439	COG5464	transposase or invertase
SDY_2456	COG0318	PFAM AMP-dependent synthetase and ligase
SDY_2458	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SDY_2461	COG1169	isochorismate synthase
SDY_2462	COG4575	ribosome binding
SDY_2463	COG2153	protein acetylation
SDY_2473	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SDY_2474	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SDY_2476	COG0839	Belongs to the complex I subunit 6 family
SDY_2479	COG1034	ATP synthesis coupled electron transport
SDY_2480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SDY_2481	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
SDY_2485	COG0583	DNA-binding transcription factor activity
SDY_2486	COG0436	Aminotransferase
SDY_2488	COG0490	domain, Protein
SDY_2488	COG0471	metal ion transport
SDY_2489	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDY_2492	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SDY_2493	COG0280	phosphate acetyltransferase
SDY_2493	COG0857	belongs to the CobB CobQ family
SDY_2494	COG1288	antiporter activity
SDY_2495	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SDY_2496	COG0622	Phosphoesterase
SDY_2499	COG0625	glutathione transferase activity
SDY_2500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SDY_2501	COG1090	epimerase
SDY_2502	COG5464	transposase or invertase
SDY_2505	COG4598	ABC transporter
SDY_2506	COG4160	amino acid transport
SDY_2507	COG4215	(ABC) transporter
SDY_2508	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDY_2509	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDY_2510	COG0163	prenyltransferase activity
SDY_2511	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SDY_2512	COG1286	toxin biosynthetic process
SDY_2513	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
SDY_2514	COG0285	dihydrofolate synthase activity
SDY_2516	COG0586	Pfam SNARE associated Golgi protein
SDY_2518	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SDY_2522	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDY_2525	COG3101	peptidyl-lysine hydroxylation
SDY_2532	COG3539	Fimbrial protein
SDY_2533	COG3539	Fimbrial protein
SDY_2534	COG3539	Fimbrial protein
SDY_2535	COG3121	Chaperone
SDY_2541	COG2062	phosphohistidine phosphatase, SixA
SDY_2544	COG3691	Protein conserved in bacteria
SDY_2545	COG2067	long-chain fatty acid transport protein
SDY_2550	COG2853	Lipoprotein
SDY_2551	COG2116	formate transmembrane transporter activity
SDY_2560	COG2610	gluconate transmembrane transporter activity
SDY_2562	COG0477	Major facilitator Superfamily
SDY_2563	COG1566	PFAM secretion protein HlyD family protein
SDY_2569	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SDY_2570	COG0679	Auxin Efflux Carrier
SDY_2571	COG0028	Belongs to the TPP enzyme family
SDY_2576	COG1560	Kdo2-lipid A biosynthetic process
SDY_2577	COG0436	Aminotransferase
SDY_2579	COG3275	phosphorelay sensor kinase activity
SDY_2583	COG1363	Peptidase, m42
SDY_2584	COG0006	proline dipeptidase activity
SDY_2585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDY_2586	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDY_2593	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SDY_2596	COG3415	Transposase
SDY_2597	COG3415	Transposase
SDY_2598	COG0675	Transposase, IS605 OrfB family
SDY_2606	COG0385	Bile acid
SDY_2607	COG3530	Putative quorum-sensing-regulated virulence factor
SDY_2611	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SDY_2612	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_2613	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SDY_2614	COG2190	(PTS) system
SDY_2617	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SDY_2618	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SDY_2619	COG4208	sulfate ABC transporter
SDY_2620	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SDY_2621	COG4150	thiosulfate binding
SDY_2622	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_2629	COG2837	iron assimilation
SDY_2633	COG0860	N-Acetylmuramoyl-L-alanine amidase
SDY_2635	COG2207	Transcriptional regulator
SDY_2636	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SDY_2637	COG4816	utilization protein
SDY_2639	COG4303	Ethanolamine ammonia lyase large subunit
SDY_2645	COG0281	malic enzyme
SDY_2645	COG0280	phosphate acetyltransferase
SDY_2649	COG5342	invasion associated locus B
SDY_2651	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SDY_2651	COG0493	'glutamate synthase
SDY_2653	COG3850	Histidine kinase
SDY_2654	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SDY_2655	COG1393	Belongs to the ArsC family
SDY_2661	COG1444	tRNA N-acetyltransferase activity
SDY_2666	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
SDY_2668	COG2716	regulation of RNA biosynthetic process
SDY_2669	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SDY_2670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SDY_2671	COG0651	ATP synthesis coupled electron transport
SDY_2672	COG0650	Formate hydrogenlyase subunit 4
SDY_2674	COG4237	Hydrogenase 4 membrane
SDY_2675	COG0651	ATP synthesis coupled electron transport
SDY_2676	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
SDY_2676	COG3261	NADH dehydrogenase
SDY_2678	COG3260	NADH ubiquinone oxidoreductase 20
SDY_2681	COG2116	formate transmembrane transporter activity
SDY_2682	COG0628	permease
SDY_2683	COG4783	chaperone-mediated protein folding
SDY_2684	COG1393	Belongs to the ArsC family
SDY_2686	COG2233	PERMEase
SDY_2689	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SDY_2690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SDY_2691	COG0248	Ppx GppA phosphatase
SDY_2699	COG3133	Outer membrane lipoprotein
SDY_2704	COG0516	GMP reductase activity
SDY_2704	COG0517	IMP dehydrogenase activity
SDY_2706	COG1645	bacterial-type flagellum-dependent swarming motility
SDY_2709	COG2976	Protein conserved in bacteria
SDY_2717	COG2897	thiosulfate sulfurtransferase activity
SDY_2720	COG2975	iron-sulfur cluster assembly
SDY_2721	COG0633	Ferredoxin
SDY_2725	COG0822	iron-sulfur transferase activity
SDY_2729	COG0483	inositol monophosphate 1-phosphatase activity
SDY_2730	COG1073	alpha beta
SDY_2731	COG3711	transcriptional antiterminator
SDY_2732	COG2814	Major facilitator Superfamily
SDY_2733	COG0583	DNA-binding transcription factor activity
SDY_2734	COG0583	DNA-binding transcription factor activity
SDY_2736	COG1879	ABC-type sugar transport system periplasmic component
SDY_2740	COG1940	carbohydrate kinase activity
SDY_2742	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SDY_2742	COG1017	nitric oxide dioxygenase activity
SDY_2743	COG0347	Belongs to the P(II) protein family
SDY_2744	COG2204	response regulator
SDY_2745	COG3170	Tfp pilus assembly protein FimV
SDY_2746	COG2205	protein histidine kinase activity
SDY_2749	COG0590	tRNA wobble adenosine to inosine editing
SDY_2750	COG0560	Phosphoserine phosphatase
SDY_2751	COG1737	Transcriptional regulator
SDY_2752	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SDY_2765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SDY_2766	COG0287	Prephenate dehydrogenase
SDY_2766	COG1605	Chorismate mutase
SDY_2767	COG0077	Prephenate dehydratase
SDY_2767	COG1605	Chorismate mutase
SDY_2768	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SDY_2769	COG3385	transposase activity
SDY_2784	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SDY_2785	COG4137	Cytochrome C assembly protein
SDY_2786	COG4536	flavin adenine dinucleotide binding
SDY_2789	COG0497	DNA recombination
SDY_2790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SDY_2792	COG2867	negative regulation of translational initiation
SDY_2801	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SDY_2809	COG0681	Belongs to the peptidase S26 family
SDY_2811	COG3086	response to oxidative stress
SDY_2812	COG3026	antisigma factor binding
SDY_2813	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
SDY_2814	COG1595	DNA-templated transcription, initiation
SDY_2815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SDY_2817	COG0513	Belongs to the DEAD box helicase family
SDY_2818	COG0583	DNA-binding transcription factor activity
SDY_2821	COG1280	lysine exporter protein (LysE YggA)
SDY_2824	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDY_2825	COG3118	belongs to the thioredoxin family
SDY_2826	COG3148	PFAM DTW domain containing protein
SDY_2827	COG1042	CoA-binding domain protein
SDY_2827	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SDY_2827	COG0045	succinate-CoA ligase (ADP-forming) activity
SDY_2828	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SDY_2829	COG5544	Lipoprotein
SDY_2830	COG0477	Major facilitator Superfamily
SDY_2835	COG0542	response to heat
SDY_2837	COG0564	pseudouridine synthase activity
SDY_2838	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SDY_2839	COG3385	transposase activity
SDY_2841	COG3436	PFAM IS66 Orf2 family protein
SDY_2851	COG1012	belongs to the aldehyde dehydrogenase family
SDY_2853	COG1113	amino acid transport
SDY_2854	COG1802	Transcriptional regulator
SDY_2855	COG1652	LysM domain
SDY_2856	COG0401	homolog of Blt101
SDY_2857	COG0640	Transcriptional regulator
SDY_2858	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SDY_2859	COG2916	Histone family protein nucleoid-structuring protein H-NS
SDY_2863	COG4575	ribosome binding
SDY_2865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SDY_2866	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SDY_2869	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SDY_2872	COG4175	Glycine betaine
SDY_2873	COG4176	ABC-type proline glycine betaine transport system permease component
SDY_2876	COG2814	Major facilitator Superfamily
SDY_2877	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SDY_2879	COG1846	Transcriptional regulator
SDY_2880	COG1566	PFAM secretion protein HlyD family protein
SDY_2887	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDY_2892	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SDY_2896	COG1546	Belongs to the CinA family
SDY_2897	COG2951	lytic endotransglycosylase activity
SDY_2898	COG3730	PTS system glucitol sorbitol-specific
SDY_2899	COG3732	PTS system glucitol sorbitol-specific
SDY_2902	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_2903	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_2904	COG1349	DNA-binding transcription factor activity
SDY_2905	COG0517	IMP dehydrogenase activity
SDY_2905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SDY_2909	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SDY_2910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SDY_2911	COG1609	Transcriptional regulator
SDY_2912	COG2723	6-phospho-beta-galactosidase activity
SDY_2913	COG5499	transcription regulator containing HTH domain
SDY_2914	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SDY_2917	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SDY_2918	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
SDY_2918	COG3261	NADH dehydrogenase
SDY_2921	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SDY_2923	COG0375	protein maturation
SDY_2924	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SDY_2925	COG0298	carbon dioxide binding
SDY_2926	COG0409	Hydrogenase expression formation protein
SDY_2927	COG0309	Hydrogenase expression formation protein (HypE)
SDY_2938	COG0163	prenyltransferase activity
SDY_2940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SDY_2941	COG1388	LysM domain
SDY_2941	COG4942	peptidase
SDY_2952	COG2234	aminopeptidase activity
SDY_2953	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDY_2967	COG0720	synthase
SDY_2968	COG0644	oxidoreductase
SDY_2969	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
SDY_2970	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SDY_2973	COG0477	Major facilitator Superfamily
SDY_2976	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_2978	COG1070	Carbohydrate kinase
SDY_2981	COG0602	queuosine metabolic process
SDY_2998	COG3956	TIGRFAM MazG family protein
SDY_2999	COG2337	Toxic component of a toxin-antitoxin (TA) module
SDY_3000	COG2336	PFAM SpoVT AbrB
SDY_3001	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SDY_3003	COG3437	response regulator, receiver
SDY_3003	COG4999	Histidine kinase
SDY_3003	COG3850	Histidine kinase
SDY_3003	COG2205	protein histidine kinase activity
SDY_3007	COG0716	FMN binding
SDY_3008	COG0564	pseudouridine synthase activity
SDY_3009	COG3098	single-species biofilm formation
SDY_3012	COG1611	Belongs to the LOG family
SDY_3013	COG0814	amino acid
SDY_3014	COG1760	l-serine dehydratase
SDY_3016	COG1454	alcohol dehydrogenase
SDY_3017	COG0235	Class ii aldolase
SDY_3021	COG1070	Carbohydrate kinase
SDY_3023	COG1349	DNA-binding transcription factor activity
SDY_3025	COG2363	Small membrane protein
SDY_3026	COG0583	DNA-binding transcription factor activity
SDY_3028	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SDY_3029	COG2166	iron-sulfur cluster assembly
SDY_3030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SDY_3031	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
SDY_3034	COG0860	N-Acetylmuramoyl-L-alanine amidase
SDY_3035	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SDY_3035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SDY_3036	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SDY_3037	COG1074	ATP-dependent DNA helicase activity
SDY_3038	COG1025	Belongs to the peptidase M16 family
SDY_3039	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SDY_3040	COG4967	type IV pilus modification protein PilV
SDY_3042	COG4795	General secretion pathway protein
SDY_3043	COG2165	general secretion pathway protein
SDY_3046	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
SDY_3049	COG0861	Integral membrane protein TerC family
SDY_3051	COG0667	Aldo Keto reductase
SDY_3054	COG1609	Transcriptional regulator
SDY_3056	COG0583	DNA-binding transcription factor activity
SDY_3057	COG1794	racemase activity, acting on amino acids and derivatives
SDY_3058	COG2814	Major facilitator Superfamily
SDY_3061	COG0656	L-ascorbic acid biosynthetic process
SDY_3062	COG2207	Transcriptional regulator
SDY_3063	COG1979	alcohol dehydrogenase
SDY_3064	COG0586	Pfam SNARE associated Golgi protein
SDY_3065	COG0626	cystathionine gamma-synthase activity
SDY_3067	COG0811	peptide transport
SDY_3068	COG0848	biopolymer transport protein
SDY_3069	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_3073	COG0667	Aldo Keto reductase
SDY_3076	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SDY_3077	COG0437	4 iron, 4 sulfur cluster binding
SDY_3078	COG5557	Pfam Polysulphide reductase, NrfD
SDY_3079	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SDY_3080	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SDY_3081	COG1773	rubredoxin
SDY_3083	COG0298	carbon dioxide binding
SDY_3084	COG0625	glutathione transferase activity
SDY_3085	COG0754	glutathionylspermidine amidase activity
SDY_3086	COG0306	phosphate transporter
SDY_3087	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SDY_3090	COG0318	PFAM AMP-dependent synthetase and ligase
SDY_3094	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SDY_3095	COG1459	type II secretion system
SDY_3096	COG2165	general secretion pathway protein
SDY_3107	COG1982	Orn Lys Arg decarboxylase major
SDY_3108	COG2211	Major facilitator Superfamily
SDY_3111	COG1194	a g-specific adenine glycosylase
SDY_3113	COG3171	Protein conserved in bacteria
SDY_3115	COG0252	asparaginase activity
SDY_3117	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SDY_3120	COG0762	integral membrane protein
SDY_3121	COG2805	Type II/IV secretion system protein
SDY_3122	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SDY_3125	COG0189	ligase activity
SDY_3126	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SDY_3127	COG2356	endonuclease I
SDY_3129	COG2814	Major facilitator Superfamily
SDY_3134	COG1166	arginine decarboxylase activity
SDY_3140	COG0501	Belongs to the peptidase M48B family
SDY_3141	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SDY_3143	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_3144	COG2213	PTS system mannitol-specific
SDY_3145	COG1063	alcohol dehydrogenase
SDY_3148	COG1072	(Pantothenic acid kinase))
SDY_3149	COG1122	ATPase activity
SDY_3157	COG0191	fructose-bisphosphate aldolase activity
SDY_3158	COG0668	transmembrane transport
SDY_3159	COG1279	arginine transmembrane transporter activity
SDY_3160	COG2968	Membrane
SDY_3169	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SDY_3170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SDY_3173	COG0006	proline dipeptidase activity
SDY_3174	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SDY_3175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SDY_3183	COG1272	protein, Hemolysin III
SDY_3185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
SDY_3187	COG0716	FMN binding
SDY_3188	COG4974	Belongs to the 'phage' integrase family
SDY_3189	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SDY_3190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SDY_3202	COG0754	glutathionylspermidine amidase activity
SDY_3205	COG1538	Outer membrane efflux protein
SDY_3206	COG0494	nUDIX hydrolase
SDY_3207	COG3151	Protein conserved in bacteria
SDY_3208	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SDY_3209	COG3150	esterase
SDY_3210	COG0187	DNA topoisomerase II activity
SDY_3211	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SDY_3212	COG2249	NAD(P)H dehydrogenase (quinone) activity
SDY_3213	COG0642	Histidine kinase
SDY_3214	COG0745	RESPONSE REGULATOR receiver
SDY_3215	COG3111	PFAM Bacterial OB fold (BOF) protein
SDY_3216	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
SDY_3217	COG4166	transmembrane transport
SDY_3218	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SDY_3219	COG0204	Acyl-transferase
SDY_3222	COG4238	major outer membrane lipoprotein
SDY_3234	COG2268	Band 7 protein
SDY_3237	COG3025	triphosphatase activity
SDY_3238	COG4991	sh3 domain protein
SDY_3241	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SDY_3243	COG0583	DNA-binding transcription factor activity
SDY_3249	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SDY_3250	COG0358	DNA primase activity
SDY_3251	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SDY_3254	COG2375	cellular response to nickel ion
SDY_3255	COG1695	Transcriptional regulator
SDY_3256	COG0840	transmembrane signaling receptor activity
SDY_3258	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SDY_3259	COG1609	Transcriptional regulator
SDY_3263	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SDY_3263	COG3408	Glycogen debranching enzyme
SDY_3265	COG1902	pentaerythritol trinitrate reductase activity
SDY_3265	COG0446	pyridine nucleotide-disulphide oxidoreductase
SDY_3266	COG5499	transcription regulator containing HTH domain
SDY_3268	COG1451	nucleotide metabolic process
SDY_3272	COG0673	inositol 2-dehydrogenase activity
SDY_3273	COG0861	Integral membrane protein TerC family
SDY_3276	COG2721	sulfolactate sulfo-lyase activity
SDY_3278	COG2271	Major facilitator Superfamily
SDY_3281	COG2186	Transcriptional regulator
SDY_3282	COG0586	Pfam SNARE associated Golgi protein
SDY_3284	COG1422	Protein of unknown function (DUF1090)
SDY_3285	COG4575	ribosome binding
SDY_3286	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
SDY_3290	COG2259	Doxx family
SDY_3291	COG0435	Glutathione S-transferase
SDY_3292	COG3152	Membrane
SDY_3297	COG0583	DNA-binding transcription factor activity
SDY_3298	COG1741	Belongs to the pirin family
SDY_3301	COG0814	amino acid
SDY_3304	COG1760	l-serine dehydratase
SDY_3306	COG1882	Formate acetyltransferase
SDY_3307	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SDY_3309	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SDY_3310	COG0583	DNA-binding transcription factor activity
SDY_3318	COG1929	Belongs to the glycerate kinase type-1 family
SDY_3319	COG2084	Dehydrogenase
SDY_3324	COG3539	Fimbrial protein
SDY_3325	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SDY_3329	COG2823	Periplasmic or secreted lipoprotein
SDY_3331	COG0702	epimerase
SDY_3332	COG0693	protein deglycase activity
SDY_3335	COG3153	acetyltransferase
SDY_3336	COG3154	lipid carrier protein
SDY_3337	COG0826	peptidase U32
SDY_3338	COG0826	peptidase U32
SDY_3339	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SDY_3340	COG0814	amino acid
SDY_3341	COG0513	Belongs to the DEAD box helicase family
SDY_3348	COG0195	Participates in both transcription termination and antitermination
SDY_3352	COG2194	sulfuric ester hydrolase activity
SDY_3356	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SDY_3358	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SDY_3359	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SDY_3361	COG1534	Rna-binding protein
SDY_3362	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SDY_3363	COG2027	D-alanyl-D-alanine carboxypeptidase
SDY_3365	COG0697	spore germination
SDY_3368	COG0142	geranyltranstransferase activity
SDY_3369	COG3423	Transcriptional regulator
SDY_3371	COG5007	Belongs to the BolA IbaG family
SDY_3372	COG3113	response to antibiotic
SDY_3373	COG2854	intermembrane phospholipid transfer
SDY_3374	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SDY_3375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SDY_3376	COG1127	ABC transporter
SDY_3377	COG0530	calcium, potassium:sodium antiporter activity
SDY_3378	COG0517	IMP dehydrogenase activity
SDY_3378	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SDY_3379	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SDY_3380	COG3117	lipopolysaccharide transmembrane transporter activity
SDY_3381	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
SDY_3382	COG1137	ATPase activity
SDY_3383	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SDY_3384	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SDY_3387	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_3388	COG0515	serine threonine protein kinase
SDY_3390	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
SDY_3391	COG0784	Response regulator, receiver
SDY_3391	COG2198	Histidine kinase
SDY_3391	COG5002	protein histidine kinase activity
SDY_3392	COG1242	4 iron, 4 sulfur cluster binding
SDY_3393	COG0069	glutamate synthase activity
SDY_3393	COG0070	glutamate synthase
SDY_3393	COG0067	glutamate synthase
SDY_3394	COG0493	'glutamate synthase
SDY_3395	COG4804	nuclease activity
SDY_3396	COG2731	YhcH YjgK YiaL family protein
SDY_3403	COG3069	C4-dicarboxylate transmembrane transporter activity
SDY_3404	COG2969	positive regulation of protein catabolic process
SDY_3405	COG0625	glutathione transferase activity
SDY_3408	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SDY_3409	COG3105	Protein conserved in bacteria
SDY_3410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SDY_3411	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SDY_3415	COG2732	(Barnase) inhibitor
SDY_3419	COG0583	DNA-binding transcription factor activity
SDY_3420	COG0312	modulator of DNA gyrase
SDY_3421	COG3164	Protein of unknown function
SDY_3422	COG1530	ribonuclease E activity
SDY_3424	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
SDY_3425	COG1792	Involved in formation and maintenance of cell shape
SDY_3426	COG1077	Cell shape determining protein MreB Mrl
SDY_3427	COG2199	diguanylate cyclase activity
SDY_3427	COG2200	EAL domain
SDY_3428	COG0604	alcohol dehydrogenase
SDY_3432	COG0511	ligase activity, forming carbon-carbon bonds
SDY_3433	COG0439	Biotin carboxylase
SDY_3434	COG3924	membrane
SDY_3435	COG4145	pantothenate transmembrane transporter activity
SDY_3437	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SDY_3439	COG2189	Belongs to the N(4) N(6)-methyltransferase family
SDY_3442	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDY_3445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDY_3447	COG0765	amino acid transport
SDY_3456	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SDY_3460	COG0551	DNA topoisomerase type I activity
SDY_3462	COG0758	DNA mediated transformation
SDY_3466	COG0569	domain protein
SDY_3468	COG0789	Transcriptional regulator
SDY_3476	COG0201	protein transport
SDY_3507	COG2964	Protein conserved in bacteria
SDY_3508	COG0545	Peptidyl-prolyl cis-trans isomerase
SDY_3510	COG1047	Peptidyl-prolyl cis-trans
SDY_3511	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
SDY_3514	COG0488	(ABC) transporter
SDY_3515	COG0429	hydrolase of the alpha beta-hydrolase fold
SDY_3518	COG1765	OsmC-like protein
SDY_3519	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SDY_3520	COG1289	transmembrane transporter activity
SDY_3521	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SDY_3522	COG0512	Glutamine amidotransferase of anthranilate synthase
SDY_3523	COG2184	nucleotidyltransferase activity
SDY_3525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SDY_3527	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SDY_3528	COG2146	nitrite reductase [NAD(P)H] activity
SDY_3529	COG2116	formate transmembrane transporter activity
SDY_3532	COG0076	glutamate decarboxylase activity
SDY_3533	COG2207	Transcriptional regulator
SDY_3537	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SDY_3538	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDY_3539	COG2771	luxR family
SDY_3542	COG3247	response to pH
SDY_3548	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDY_3550	COG3721	Heme iron utilization protein
SDY_3552	COG4558	Periplasmic binding protein
SDY_3554	COG4771	TonB-dependent receptor
SDY_3555	COG3720	iron ion transport
SDY_3556	COG2197	response regulator
SDY_3557	COG3065	identical protein binding
SDY_3559	COG1393	Belongs to the ArsC family
SDY_3560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SDY_3561	COG0640	Transcriptional regulator
SDY_3562	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SDY_3563	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
SDY_3564	COG0339	signal peptide processing
SDY_3567	COG0589	response to stress
SDY_3569	COG0306	phosphate transporter
SDY_3570	COG2081	HI0933 family
SDY_3574	COG0058	SHG alpha-glucan phosphorylase activity
SDY_3579	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SDY_3580	COG2095	MarC family integral membrane protein
SDY_3586	COG0514	ATP-dependent DNA helicase (RecQ)
SDY_3587	COG2610	gluconate transmembrane transporter activity
SDY_3588	COG3265	gluconokinase activity
SDY_3589	COG1609	Transcriptional regulator
SDY_3590	COG1741	Belongs to the pirin family
SDY_3591	COG0673	inositol 2-dehydrogenase activity
SDY_3592	COG1247	-acetyltransferase
SDY_3595	COG0405	Gamma-glutamyltransferase
SDY_3603	COG0410	ABC transporter
SDY_3604	COG0411	ABC transporter
SDY_3605	COG4177	L-phenylalanine transmembrane transporter activity
SDY_3606	COG0559	Belongs to the binding-protein-dependent transport system permease family
SDY_3607	COG0683	leucine binding
SDY_3610	COG0456	acetyltransferase
SDY_3611	COG0683	leucine binding
SDY_3612	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SDY_3613	COG2177	Part of the ABC transporter FtsEX involved in
SDY_3614	COG2884	Cell division ATP-binding protein ftsE
SDY_3615	COG0552	protein localization to endoplasmic reticulum
SDY_3616	COG0742	ribosomal rna small subunit methyltransferase
SDY_3617	COG3776	membrane
SDY_3622	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SDY_3629	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDY_3630	COG2091	lysine biosynthetic process via aminoadipic acid
SDY_3631	COG0747	negative chemotaxis
SDY_3632	COG0601	transmembrane transport
SDY_3633	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SDY_3642	COG3414	Phosphotransferase system galactitol-specific IIB component
SDY_3649	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SDY_3652	COG1349	DNA-binding transcription factor activity
SDY_3653	COG1690	Belongs to the RtcB family
SDY_3654	COG4650	regulator
SDY_3659	COG0058	SHG alpha-glucan phosphorylase activity
SDY_3660	COG1640	4-alpha-glucanotransferase
SDY_3661	COG2610	gluconate transmembrane transporter activity
SDY_3665	COG5464	transposase or invertase
SDY_3667	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SDY_3668	COG1918	ferrous iron import across plasma membrane
SDY_3669	COG2183	response to ionizing radiation
SDY_3670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SDY_3674	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
SDY_3678	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SDY_3679	COG1011	Hydrolase
SDY_3681	COG0494	nUDIX hydrolase
SDY_3682	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SDY_3685	COG3166	PFAM Fimbrial assembly family protein
SDY_3691	COG3266	domain, Protein
SDY_3692	COG0338	D12 class N6 adenine-specific DNA methyltransferase
SDY_3693	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SDY_3695	COG0180	Tryptophanyl-tRNA synthetase
SDY_3696	COG2188	Transcriptional regulator
SDY_3701	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SDY_3702	COG1735	metal-dependent hydrolase with the TIM-barrel fold
SDY_3706	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SDY_3707	COG3977	Valine--pyruvate aminotransferase
SDY_3709	COG2992	FlgJ-related protein
SDY_3710	COG2207	Transcriptional regulator
SDY_3710	COG1609	Transcriptional regulator
SDY_3721	COG0151	Belongs to the GarS family
SDY_3722	COG2204	response regulator
SDY_3723	COG4191	Histidine kinase
SDY_3724	COG3678	ATP-independent chaperone mediated protein folding
SDY_3727	COG3068	Protein conserved in bacteria
SDY_3734	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SDY_3735	COG2104	thiamine diphosphate biosynthetic process
SDY_3737	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SDY_3746	COG0250	Participates in transcription elongation, termination and antitermination
SDY_3747	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SDY_3755	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SDY_3755	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SDY_3761	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SDY_3765	COG1309	transcriptional regulator
SDY_3772	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
SDY_3774	COG0626	cystathionine gamma-synthase activity
SDY_3775	COG0527	aspartate kinase activity
SDY_3775	COG0460	homoserine dehydrogenase
SDY_3776	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SDY_3778	COG0697	spore germination
SDY_3779	COG3738	Protein conserved in bacteria
SDY_3780	COG0371	Dehydrogenase
SDY_3781	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SDY_3782	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_3782	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDY_3782	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SDY_3784	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDY_3785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDY_3786	COG1882	Formate acetyltransferase
SDY_3787	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDY_3788	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDY_3789	COG2207	Transcriptional regulator
SDY_3790	COG2194	sulfuric ester hydrolase activity
SDY_3793	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SDY_3796	COG0583	DNA-binding transcription factor activity
SDY_3800	COG3209	COG3209 Rhs family protein
SDY_3802	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SDY_3803	COG1609	Transcriptional regulator
SDY_3804	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SDY_3807	COG1575	Belongs to the MenA family. Type 1 subfamily
SDY_3817	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDY_3819	COG1494	fructose-1,6-bisphosphatase
SDY_3821	COG0589	response to stress
SDY_3822	COG3691	Protein conserved in bacteria
SDY_3824	COG3152	Membrane
SDY_3830	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
SDY_3833	COG3678	ATP-independent chaperone mediated protein folding
SDY_3834	COG0745	RESPONSE REGULATOR receiver
SDY_3835	COG2205	protein histidine kinase activity
SDY_3836	COG2258	MOSC domain
SDY_3838	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SDY_3850	COG0437	4 iron, 4 sulfur cluster binding
SDY_3851	COG2864	formate dehydrogenase
SDY_3855	COG0456	acetyltransferase
SDY_3858	COG1011	Hydrolase
SDY_3867	COG0477	Major facilitator Superfamily
SDY_3871	COG3385	transposase activity
SDY_3872	COG1217	gtp-binding protein TYPA
SDY_3873	COG0174	glutamine synthetase
SDY_3874	COG3852	Histidine kinase
SDY_3875	COG2204	response regulator
SDY_3876	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SDY_3877	COG3078	GTPase activator activity
SDY_3879	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDY_3879	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDY_3880	COG0204	Acyl-transferase
SDY_3885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SDY_3886	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SDY_3887	COG3084	Protein conserved in bacteria
SDY_3888	COG0746	molybdenum cofactor guanylyltransferase activity
SDY_3889	COG1763	Mo-molybdopterin cofactor biosynthetic process
SDY_3895	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
SDY_3896	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SDY_3897	COG1739	Uncharacterized protein family UPF0029
SDY_3901	COG0543	2 iron, 2 sulfur cluster binding
SDY_3903	COG0250	Participates in transcription elongation, termination and antitermination
SDY_3905	COG0805	protein transport
SDY_3907	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SDY_3909	COG3165	ubiquinone biosynthetic process from chorismate
SDY_3911	COG1322	Protein conserved in bacteria
SDY_3912	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SDY_3913	COG0412	Dienelactone hydrolase
SDY_3915	COG0583	DNA-binding transcription factor activity
SDY_3916	COG0697	spore germination
SDY_3917	COG0561	phosphatase activity
SDY_3918	COG2267	carboxylic ester hydrolase activity
SDY_3919	COG1280	lysine exporter protein (LysE YggA)
SDY_3920	COG1280	lysine exporter protein (LysE YggA)
SDY_3921	COG0514	ATP-dependent DNA helicase (RecQ)
SDY_3922	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
SDY_3923	COG2050	protein possibly involved in aromatic compounds catabolism
SDY_3924	COG2962	Rard protein
SDY_3929	COG0598	Magnesium transport protein CorA
SDY_3930	COG3698	Phosphodiester glycosidase
SDY_3931	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
SDY_3932	COG0210	DNA helicase
SDY_3933	COG1011	Hydrolase
SDY_3935	COG3159	Protein conserved in bacteria
SDY_3937	COG5567	small periplasmic lipoprotein
SDY_3940	COG3072	Adenylate cyclase
SDY_3942	COG1587	Uroporphyrinogen-III synthase
SDY_3943	COG2959	enzyme of heme biosynthesis
SDY_3944	COG3071	HemY protein
SDY_3945	COG3119	arylsulfatase activity
SDY_3952	COG1113	amino acid transport
SDY_3956	COG2244	polysaccharide biosynthetic process
SDY_3957	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SDY_3958	COG0456	acetyltransferase
SDY_3959	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SDY_3961	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SDY_3962	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SDY_3963	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
SDY_3964	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SDY_3966	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SDY_3968	COG3118	belongs to the thioredoxin family
SDY_3971	COG0210	DNA helicase
SDY_3972a	COG3692	DNA binding
SDY_3973	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SDY_3975	COG0583	DNA-binding transcription factor activity
SDY_3976	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SDY_3978	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SDY_3979	COG3978	acetolactate synthase activity
SDY_3983	COG3547	Transposase (IS116 IS110 IS902 family)
SDY_3984	COG3085	chromosome segregation
SDY_3992	COG2186	Transcriptional regulator
SDY_3993	COG0477	Major facilitator Superfamily
SDY_3994	COG1609	Transcriptional regulator
SDY_3995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDY_3997	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDY_4005	COG1522	sequence-specific DNA binding
SDY_4006	COG0716	FMN binding
SDY_4009	COG3312	ion transport
SDY_4019	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SDY_4022	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SDY_4023	COG0573	inorganic phosphate transmembrane transporter activity
SDY_4024	COG0581	inorganic phosphate transmembrane transporter activity
SDY_4025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SDY_4026	COG0704	Plays a role in the regulation of phosphate uptake
SDY_4033	COG5295	Hep Hag repeat protein
SDY_4034	COG5295	Hep Hag repeat protein
SDY_4035	COG5295	Hep Hag repeat protein
SDY_4036	COG1620	l-lactate permease
SDY_4037	COG2186	Transcriptional regulator
SDY_4039	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SDY_4040	COG1045	serine acetyltransferase
SDY_4043	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SDY_4044	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SDY_4046	COG4942	peptidase
SDY_4047	COG2861	carbohydrate metabolic process
SDY_4048	COG1216	Glycosyl transferase, family 2
SDY_4050	COG0156	8-amino-7-oxononanoate synthase activity
SDY_4052	COG0859	PFAM glycosyl transferase family 9
SDY_4053	COG0859	PFAM glycosyl transferase family 9
SDY_4054	COG3307	-O-antigen
SDY_4056	COG1442	glycosyl transferase family 8
SDY_4057	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SDY_4060	COG0515	serine threonine protein kinase
SDY_4061	COG0438	transferase activity, transferring glycosyl groups
SDY_4062	COG0859	PFAM glycosyl transferase family 9
SDY_4063	COG1519	Transferase
SDY_4069	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SDY_4075	COG1561	YicC-like family, N-terminal region
SDY_4076	COG3645	SOS response
SDY_4077	COG2860	membrane
SDY_4082	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SDY_4083	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDY_4084	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SDY_4085	COG0786	glutamate:sodium symporter activity
SDY_4086	COG2233	PERMEase
SDY_4087	COG2982	Protein involved in outer membrane biogenesis
SDY_4088	COG1501	Belongs to the glycosyl hydrolase 31 family
SDY_4091	COG2211	Major facilitator Superfamily
SDY_4092	COG1486	melibiose metabolic process
SDY_4094	COG1982	Orn Lys Arg decarboxylase major
SDY_4097	COG2207	Transcriptional regulator
SDY_4098	COG0531	amino acid
SDY_4099	COG2194	sulfuric ester hydrolase activity
SDY_4101	COG0642	Histidine kinase
SDY_4102	COG0477	Major facilitator Superfamily
SDY_4109	COG2824	Alkylphosphonate utilization operon protein PhnA
SDY_4112	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SDY_4113	COG3639	organic phosphonate transmembrane transporter activity
SDY_4114	COG2188	Transcriptional regulator
SDY_4116	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
SDY_4117	COG3626	phosphonate metabolism
SDY_4118	COG3627	carbon phosphorus lyase activity
SDY_4119	COG4107	phosphonate C-P lyase system protein PhnK
SDY_4120	COG4778	phosphonate C-P lyase system protein PhnL
SDY_4121	COG3454	Phosphonate metabolism
SDY_4123	COG0456	acetyltransferase
SDY_4124	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SDY_4137	COG1388	LysM domain
SDY_4137	COG1470	cell adhesion involved in biofilm formation
SDY_4138	COG1388	LysM domain
SDY_4138	COG1470	cell adhesion involved in biofilm formation
SDY_4147	COG2271	Major facilitator Superfamily
SDY_4148	COG2271	Major facilitator Superfamily
SDY_4149	COG3851	Histidine kinase
SDY_4150	COG2197	response regulator
SDY_4154	COG0440	acetolactate synthase activity
SDY_4155	COG0028	Belongs to the TPP enzyme family
SDY_4157	COG2814	Major facilitator Superfamily
SDY_4158	COG0641	radical SAM
SDY_4160	COG2149	membrane
SDY_4162	COG3119	arylsulfatase activity
SDY_4170	COG2188	Transcriptional regulator
SDY_4174	COG5645	(Lipo)protein
SDY_4175	COG0823	Involved in the tonB-independent uptake of proteins
SDY_4179	COG0561	phosphatase activity
SDY_4180	COG3753	Protein conserved in bacteria
SDY_4181	COG0187	DNA topoisomerase II activity
SDY_4183	COG0592	DNA-directed DNA polymerase activity
SDY_4198	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDY_4199	COG2252	PERMEase
SDY_4201	COG2091	lysine biosynthetic process via aminoadipic acid
SDY_4204	COG0814	amino acid
SDY_4210	COG3209	COG3209 Rhs family protein
SDY_4211	COG0625	glutathione transferase activity
SDY_4213	COG3276	selenocysteine insertion sequence binding
SDY_4227	COG0527	aspartate kinase activity
SDY_4231	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SDY_4231	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SDY_4232	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SDY_4237	COG4565	transcriptional regulatory protein
SDY_4238	COG3290	protein histidine kinase activity
SDY_4239	COG3592	Divergent 4Fe-4S mono-cluster
SDY_4240	COG2388	GCN5-related N-acetyl-transferase
SDY_4247	COG1129	ABC transporter
SDY_4248	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDY_4249	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDY_4251	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SDY_4253	COG0312	modulator of DNA gyrase
SDY_4255	COG3077	Addiction module antitoxin, RelB DinJ family
SDY_4255a	COG3783	Cytochrome b(562)
SDY_4256	COG0602	queuosine metabolic process
SDY_4257	COG1328	CTP reductase activity
SDY_4258	COG0366	Alpha amylase catalytic
SDY_4259	COG1263	PTS System
SDY_4259	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDY_4260	COG1609	Transcriptional regulator
SDY_4261	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SDY_4262	COG0251	oxidation-reduction process
SDY_4266	COG0251	oxidation-reduction process
SDY_4267	COG1028	Short-chain dehydrogenase reductase Sdr
SDY_4269	COG1309	transcriptional regulator
SDY_4270	COG2731	YhcH YjgK YiaL family protein
SDY_4277	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
SDY_4278	COG0456	acetyltransferase
SDY_4280	COG4269	membrane
SDY_4283	COG2927	DNA polymerase III (CHI subunit)
SDY_4285	COG0795	lipopolysaccharide-transporting ATPase activity
SDY_4286	COG0795	lipopolysaccharide-transporting ATPase activity
SDY_4287	COG0433	COG0433 Predicted ATPase
SDY_4288	COG1064	alcohol dehydrogenase
SDY_4290	COG0582	viral genome integration into host DNA
SDY_4293	COG1120	ATPase activity
SDY_4294	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDY_4295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDY_4297	COG4772	TonB-dependent receptor
SDY_4299	COG1595	DNA-templated transcription, initiation
SDY_4302	COG3677	Transposase
SDY_4310	COG1187	pseudouridine synthase activity
SDY_4319	COG1283	sodium-dependent phosphate transmembrane transporter activity
SDY_4322	COG0646	methionine synthase
SDY_4322	COG1410	methionine synthase
SDY_4323	COG1414	Transcriptional regulator
SDY_4328	COG2224	Isocitrate lyase
SDY_4333	COG0456	acetyltransferase
SDY_4335	COG3385	transposase activity
SDY_4336	COG4213	ABC transporter substrate-binding protein
SDY_4340	COG3274	enterobacterial common antigen metabolic process
SDY_4347	COG1278	Cold shock
SDY_4348	COG2944	sequence-specific DNA binding
SDY_4351	COG2885	chlorophyll binding
SDY_4352	COG0243	molybdopterin cofactor binding
SDY_4353	COG2818	Glycosylase
SDY_4358	COG3650	response to hydrogen peroxide
SDY_4359	COG1073	alpha beta
SDY_4371	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SDY_4376	COG3061	Opacity-associated protein A
SDY_4377	COG0545	Peptidyl-prolyl cis-trans isomerase
SDY_4378	COG1113	amino acid transport
SDY_4380	COG0697	spore germination
SDY_4381	COG1733	regulation of RNA biosynthetic process
SDY_4382	COG0702	epimerase
SDY_4383	COG0737	Belongs to the 5'-nucleotidase family
SDY_4385	COG1218	3'(2'),5'-bisphosphate nucleotidase
SDY_4389	COG1509	lysine 2,3-aminomutase activity
SDY_4391	COG5510	response to toxic substance
SDY_4392	COG2076	Multidrug Resistance protein
SDY_4393	COG3040	lipid binding
SDY_4394	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SDY_4397	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SDY_4398	COG1053	succinate dehydrogenase
SDY_4402	COG5463	Belongs to the UPF0441 family
SDY_4403	COG0754	glutathionylspermidine amidase activity
SDY_4404	COG1960	acyl-CoA dehydrogenase activity
SDY_4409	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDY_4410	COG0557	exoribonuclease II activity
SDY_4413	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
SDY_4414	COG0330	HflC and HflK could
SDY_4415	COG0330	HflC and HflK could
SDY_4416	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SDY_4420	COG0860	N-Acetylmuramoyl-L-alanine amidase
SDY_4421	COG0802	atpase or kinase
SDY_4426	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SDY_4426	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SDY_4433	COG3264	Mechanosensitive ion channel
SDY_4433	COG1511	domain protein
SDY_4434	COG0531	amino acid
SDY_4443	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SDY_4444	COG1027	Aspartate ammonia-lyase
SDY_4445	COG3030	protein affecting phage T7 exclusion by the F plasmid
SDY_4447	COG0531	amino acid
SDY_4453	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
SDY_4455	COG1253	flavin adenine dinucleotide binding
SDY_4457	COG0729	surface antigen
SDY_4458	COG2911	Protein conserved in bacteria
SDY_4459	COG2105	PFAM AIG2 family protein
SDY_4460	COG2336	PFAM SpoVT AbrB
SDY_4461	COG2337	Toxic component of a toxin-antitoxin (TA) module
SDY_4462	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SDY_4463	COG1879	ABC-type sugar transport system periplasmic component
SDY_4465	COG0531	amino acid
SDY_4467	COG3104	oligopeptide transport
SDY_4468	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SDY_4474	COG3328	transposase activity
SDY_4477	COG2197	response regulator
SDY_4478	COG2205	protein histidine kinase activity
SDY_4478	COG2198	Histidine kinase
SDY_4478	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDY_4478	COG0784	Response regulator, receiver
SDY_4479	COG4372	Transposase
SDY_4480	COG3436	PFAM IS66 Orf2 family protein
SDY_4481	COG3436	PFAM IS66 Orf2 family protein
SDY_4498	COG0697	spore germination
SDY_4499	COG1464	Belongs to the NlpA lipoprotein family
SDY_4502	COG0025	NhaP-type Na H and K H
SDY_4503	COG2252	PERMEase
SDY_4504	COG0789	Transcriptional regulator
SDY_4505	COG2207	Transcriptional regulator
SDY_4508	COG0629	single-stranded DNA binding
SDY_4509	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SDY_4510	COG2315	Protein conserved in bacteria
SDY_4511	COG0432	Pfam Uncharacterised protein family UPF0047
SDY_4520	COG1448	Aminotransferase
SDY_4522	COG0305	Participates in initiation and elongation during chromosome replication
SDY_4523	COG0604	alcohol dehydrogenase
SDY_4525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SDY_4528	COG0735	belongs to the Fur family
SDY_4529	COG3237	CsbD-like
SDY_4530	COG0534	Mate efflux family protein
SDY_4532	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SDY_4538	COG1566	PFAM secretion protein HlyD family protein
SDY_4539	COG0583	DNA-binding transcription factor activity
SDY_4541	COG0583	DNA-binding transcription factor activity
SDY_4542	COG1295	ribonuclease BN
SDY_4543	COG0477	Major facilitator Superfamily
SDY_4544	COG2982	Protein involved in outer membrane biogenesis
SDY_4545	COG2200	EAL domain
SDY_4547	COG0612	Peptidase, M16
SDY_4549	COG2200	EAL domain
SDY_4549	COG2199	diguanylate cyclase activity
SDY_4552	COG1215	transferase activity, transferring glycosyl groups
SDY_4553	COG1215	transferase activity, transferring glycosyl groups
SDY_4562	COG0814	amino acid
SDY_4563	COG4608	Belongs to the ABC transporter superfamily
SDY_4564	COG0444	Belongs to the ABC transporter superfamily
SDY_4565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SDY_4566	COG0601	transmembrane transport
SDY_4567	COG0747	negative chemotaxis
SDY_4569	COG2194	sulfuric ester hydrolase activity
SDY_4575	COG1501	Belongs to the glycosyl hydrolase 31 family
SDY_4578	COG2211	Major facilitator Superfamily
SDY_4580	COG0582	viral genome integration into host DNA
SDY_4587	COG3468	outer membrane autotransporter barrel domain protein
SDY_4590	COG2003	Belongs to the UPF0758 family
SDY_4596	COG1924	4 iron, 4 sulfur cluster binding
SDY_4599	COG2814	Major facilitator Superfamily
SDY_4601	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SDY_4602	COG5457	Domain of unknown function (DUF1127)
SDY_4605	COG0523	cobalamin synthesis protein
SDY_4606	COG2879	small protein
SDY_4607	COG1966	Carbon starvation protein
SDY_4612	COG1063	alcohol dehydrogenase
SDY_4615	COG1484	DNA-dependent DNA replication
SDY_4625	COG4114	ferric iron reductase
SDY_4631	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
SDY_4632	COG0456	acetyltransferase
SDY_4633	COG1011	Hydrolase
SDY_4636	COG2823	Periplasmic or secreted lipoprotein
SDY_4637	COG4667	esterase of the alpha-beta hydrolase superfamily
SDY_4638	COG0084	hydrolase, TatD family'
SDY_4639	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDY_4640	COG1328	CTP reductase activity
SDY_4648	COG3726	membrane protein affecting hemolysin expression
SDY_4649	COG0560	Phosphoserine phosphatase
SDY_4650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SDY_4651	COG3172	ATPase kinase involved in NAD metabolism
SDY_4651	COG1056	cytidyltransferase-related domain
SDY_4652	COG0488	(ABC) transporter
SDY_4653	COG0741	lytic transglycosylase activity
SDY_4657	COG2207	Transcriptional regulator
SDY_4657	COG3708	Transcriptional regulator
SDY_4658	COG3045	CreA protein
SDY_4659	COG0745	RESPONSE REGULATOR receiver
SDY_4662	COG0745	RESPONSE REGULATOR receiver
SDY_4664	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SDY_P003	COG0527	aspartate kinase activity
SDY_P003	COG0460	homoserine dehydrogenase
SDY_P026	COG1049	propionate catabolic process, 2-methylcitrate cycle
SDY_P044	COG0196	riboflavin kinase activity
SDY_P059	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SDY_P098	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SDY_P136	COG0028	Belongs to the TPP enzyme family
SDY_P167	COG1459	type II secretion system
SDY_P181	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SDY_P182	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SDY_P199	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SDY_P203	COG1643	Atp-dependent helicase
SDY_P209	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDY_PA01	COG0460	homoserine dehydrogenase
SDY_PA01	COG0527	aspartate kinase activity
SDY_PA02	COG0527	aspartate kinase activity
SDY_PA02	COG0460	homoserine dehydrogenase