locus-tag	class	description
B7485_RS00010	COG0527	aspartate kinase activity
B7485_RS00010	COG0460	homoserine dehydrogenase
B7485_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7485_RS00040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7485_RS00045	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7485_RS00050	COG1584	GPR1 FUN34 yaaH family protein
B7485_RS00055	COG4735	regulation of single-species biofilm formation
B7485_RS00085	COG0583	DNA-binding transcription factor activity
B7485_RS00110	COG0196	riboflavin kinase activity
B7485_RS00125	COG1047	Peptidyl-prolyl cis-trans
B7485_RS00145	COG0505	Belongs to the CarA family
B7485_RS00150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7485_RS00210	COG2271	Major facilitator Superfamily
B7485_RS00225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7485_RS00250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7485_RS00260	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B7485_RS00265	COG0564	pseudouridine synthase activity
B7485_RS00275	COG0417	DNA replication proofreading
B7485_RS00280	COG0235	Class ii aldolase
B7485_RS00295	COG4977	sequence-specific DNA binding
B7485_RS00300	COG0586	Pfam SNARE associated Golgi protein
B7485_RS00310	COG1178	ABC-type Fe3 transport system permease component
B7485_RS00315	COG4143	(ABC) transporter
B7485_RS00330	COG2814	Major facilitator Superfamily
B7485_RS00360	COG0583	DNA-binding transcription factor activity
B7485_RS00365	COG0028	Belongs to the TPP enzyme family
B7485_RS00370	COG0440	acetolactate synthase activity
B7485_RS00380	COG1609	Transcriptional regulator
B7485_RS00400	COG3116	cell division
B7485_RS00405	COG0768	penicillin binding
B7485_RS00415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B7485_RS00430	COG0772	Belongs to the SEDS family
B7485_RS00450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B7485_RS00455	COG0849	cell division
B7485_RS00460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B7485_RS00480	COG0494	nUDIX hydrolase
B7485_RS00505	COG1459	type II secretion system
B7485_RS00515	COG4969	Belongs to the N-Me-Phe pilin family
B7485_RS00520	COG0157	Belongs to the NadC ModD family
B7485_RS00525	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7485_RS00530	COG3725	Membrane protein required for beta-lactamase induction
B7485_RS00540	COG2186	Transcriptional regulator
B7485_RS00545	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B7485_RS00550	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7485_RS00555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7485_RS00565	COG1049	propionate catabolic process, 2-methylcitrate cycle
B7485_RS00590	COG2132	Multicopper oxidase
B7485_RS00595	COG4993	Dehydrogenase
B7485_RS00600	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B7485_RS00605	COG0288	reversible hydration of carbon dioxide
B7485_RS00610	COG1131	(ABC) transporter
B7485_RS00615	COG0842	Transport permease protein
B7485_RS00620	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS00625	COG0726	polysaccharide deacetylase
B7485_RS00635	COG5464	transposase or invertase
B7485_RS00660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B7485_RS00665	COG0617	tRNA 3'-terminal CCA addition
B7485_RS00675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7485_RS00685	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B7485_RS00690	COG1643	Atp-dependent helicase
B7485_RS00695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7485_RS00700	COG4774	siderophore transport
B7485_RS00705	COG1120	ATPase activity
B7485_RS00710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7485_RS00715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7485_RS00740	COG2860	membrane
B7485_RS00760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7485_RS00785	COG0024	Methionine aminopeptidase
B7485_RS00815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7485_RS00820	COG0575	Belongs to the CDS family
B7485_RS00825	COG0750	zinc metalloprotease
B7485_RS00835	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B7485_RS00840	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7485_RS00865	COG0587	DNA-directed DNA polymerase activity
B7485_RS00875	COG1982	Orn Lys Arg decarboxylase major
B7485_RS00880	COG0346	lactoylglutathione lyase activity
B7485_RS00890	COG4568	rho-dependent transcription termination
B7485_RS00900	COG4681	YaeQ
B7485_RS00905	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B7485_RS00910	COG3015	lipoprotein NlpE involved in copper resistance
B7485_RS00915	COG0791	NLP P60 protein
B7485_RS00925	COG1720	tRNA m6t6A37 methyltransferase activity
B7485_RS00935	COG1464	Belongs to the NlpA lipoprotein family
B7485_RS00940	COG2011	ABC-type metal ion transport system permease component
B7485_RS00945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7485_RS00950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B7485_RS00985	COG0656	L-ascorbic acid biosynthetic process
B7485_RS00990	COG3385	transposase activity
B7485_RS00995	COG0583	DNA-binding transcription factor activity
B7485_RS01005	COG2226	methyltransferase
B7485_RS01010	COG1388	LysM domain
B7485_RS01010	COG0741	lytic transglycosylase activity
B7485_RS01020	COG2226	methyltransferase
B7485_RS01030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7485_RS01165	COG1785	Belongs to the alkaline phosphatase family
B7485_RS01175	COG1181	Belongs to the D-alanine--D-alanine ligase family
B7485_RS01195	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
B7485_RS01200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7485_RS01205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7485_RS01250	COG0113	porphobilinogen synthase activity
B7485_RS01255	COG2175	clavaminate synthase activity
B7485_RS01260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7485_RS01270	COG4521	taurine ABC transporter
B7485_RS01290	COG1556	Lactate utilization protein
B7485_RS01295	COG1139	Iron-sulfur cluster binding protein
B7485_RS01300	COG0247	lactate metabolic process
B7485_RS01360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7485_RS01370	COG1960	acyl-CoA dehydrogenase activity
B7485_RS01380	COG0121	glutamine amidotransferase
B7485_RS01385	COG3034	peptidoglycan biosynthetic process
B7485_RS01390	COG0791	NLP P60 protein
B7485_RS01395	COG1943	Transposase
B7485_RS01415	COG2161	toxin-antitoxin pair type II binding
B7485_RS01425	COG0454	-acetyltransferase
B7485_RS01430	COG1690	Belongs to the RtcB family
B7485_RS01440	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7485_RS01460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B7485_RS01485	COG0582	viral genome integration into host DNA
B7485_RS01525	COG2246	polysaccharide biosynthetic process
B7485_RS01570	COG0582	viral genome integration into host DNA
B7485_RS01595	COG3706	GGDEF domain
B7485_RS01600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7485_RS01620	COG4126	flavin adenine dinucleotide binding
B7485_RS01645	COG1940	carbohydrate kinase activity
B7485_RS01650	COG2814	Major facilitator Superfamily
B7485_RS01655	COG0419	ATPase involved in DNA repair
B7485_RS01660	COG0420	3'-5' exonuclease activity
B7485_RS01665	COG0745	RESPONSE REGULATOR receiver
B7485_RS01670	COG5002	protein histidine kinase activity
B7485_RS01675	COG1114	Component of the transport system for branched-chain amino acids
B7485_RS01680	COG1113	amino acid transport
B7485_RS01685	COG0366	Alpha amylase catalytic
B7485_RS01705	COG1862	Preprotein translocase
B7485_RS01710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7485_RS01715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7485_RS01720	COG1403	HNH endonuclease
B7485_RS01725	COG3248	Nucleoside-binding outer membrane protein
B7485_RS01730	COG4238	major outer membrane lipoprotein
B7485_RS01740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7485_RS01740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7485_RS01755	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B7485_RS01760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B7485_RS01765	COG0667	Aldo Keto reductase
B7485_RS01775	COG0142	geranyltranstransferase activity
B7485_RS01790	COG0693	protein deglycase activity
B7485_RS01795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B7485_RS01840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7485_RS01845	COG1845	cytochrome c oxidase, subunit III
B7485_RS01865	COG3436	PFAM IS66 Orf2 family protein
B7485_RS01880	COG2223	nitrite transmembrane transporter activity
B7485_RS01885	COG3056	Lipoprotein
B7485_RS01890	COG0271	Belongs to the BolA IbaG family
B7485_RS01910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B7485_RS01915	COG0776	regulation of translation
B7485_RS01920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7485_RS01925	COG1555	photosystem II stabilization
B7485_RS01930	COG0824	Thioesterase
B7485_RS01940	COG4533	DNA binding
B7485_RS01950	COG1522	sequence-specific DNA binding
B7485_RS01955	COG1132	(ABC) transporter
B7485_RS01960	COG1132	(ABC) transporter
B7485_RS01965	COG0347	Belongs to the P(II) protein family
B7485_RS01970	COG0004	ammonium transporteR
B7485_RS01975	COG1946	Acyl-CoA thioesterase
B7485_RS01980	COG3126	Type III secretion system lipoprotein chaperone (YscW)
B7485_RS01985	COG3385	transposase activity
B7485_RS01990	COG3695	enzyme binding
B7485_RS02000	COG5507	3-demethylubiquinone-9 3-methyltransferase
B7485_RS02005	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B7485_RS02015	COG0110	maltose O-acetyltransferase activity
B7485_RS02030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7485_RS02035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS02040	COG1309	transcriptional regulator
B7485_RS02045	COG3264	Mechanosensitive ion channel
B7485_RS02045	COG1196	nuclear chromosome segregation
B7485_RS02055	COG3923	Primosomal replication protein n
B7485_RS02060	COG2832	Protein of unknown function (DUF454)
B7485_RS02070	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7485_RS02110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7485_RS02110	COG4651	solute:proton antiporter activity
B7485_RS02115	COG2223	nitrite transmembrane transporter activity
B7485_RS02120	COG0737	Belongs to the 5'-nucleotidase family
B7485_RS02125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7485_RS02130	COG3735	TraB family
B7485_RS02140	COG3093	addiction module antidote protein HigA
B7485_RS02145	COG2217	Heavy metal translocating P-type atpase
B7485_RS02155	COG0531	amino acid
B7485_RS02160	COG0789	Transcriptional regulator
B7485_RS02165	COG1585	Membrane protein implicated in regulation of membrane protease activity
B7485_RS02170	COG0330	HflC and HflK could
B7485_RS02175	COG4619	ABC transporter
B7485_RS02180	COG0390	transport system, permease component
B7485_RS02185	COG3118	belongs to the thioredoxin family
B7485_RS02190	COG0300	oxidoreductase activity
B7485_RS02200	COG4181	ATPase activity
B7485_RS02205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B7485_RS02210	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B7485_RS02220	COG0583	DNA-binding transcription factor activity
B7485_RS02230	COG1414	Transcriptional regulator
B7485_RS02235	COG3960	tartronate-semialdehyde synthase activity
B7485_RS02250	COG3257	ureidoglycine aminohydrolase activity
B7485_RS02255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7485_RS02265	COG0549	Belongs to the carbamate kinase family
B7485_RS02270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B7485_RS02275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B7485_RS02285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7485_RS02295	COG1988	membrane-bound metal-dependent
B7485_RS02300	COG2501	S4 domain
B7485_RS02310	COG3539	Fimbrial protein
B7485_RS02315	COG3121	Chaperone
B7485_RS02340	COG2207	Transcriptional regulator
B7485_RS02355	COG1215	transferase activity, transferring glycosyl groups
B7485_RS02360	COG5002	protein histidine kinase activity
B7485_RS02365	COG0745	RESPONSE REGULATOR receiver
B7485_RS02370	COG1538	Outer membrane efflux protein
B7485_RS02380	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS02420	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7485_RS02425	COG1113	amino acid transport
B7485_RS02430	COG0668	transmembrane transport
B7485_RS02435	COG0778	Nitroreductase
B7485_RS02440	COG2315	Protein conserved in bacteria
B7485_RS02490	COG2977	Belongs to the P-Pant transferase superfamily
B7485_RS02495	COG4771	TonB-dependent receptor
B7485_RS02500	COG2382	esterase
B7485_RS02505	COG3251	PFAM MbtH domain protein
B7485_RS02525	COG1120	ATPase activity
B7485_RS02530	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7485_RS02535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7485_RS02545	COG4592	Periplasmic binding protein
B7485_RS02555	COG1021	2,3-dihydroxybenzoate-AMP ligase
B7485_RS02560	COG1535	isochorismatase
B7485_RS02560	COG3433	isochorismatase activity
B7485_RS02565	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS02570	COG2050	protein possibly involved in aromatic compounds catabolism
B7485_RS02575	COG1966	Carbon starvation protein
B7485_RS02580	COG2879	small protein
B7485_RS02585	COG0371	Dehydrogenase
B7485_RS02590	COG0436	Aminotransferase
B7485_RS02605	COG1475	DNA binding
B7485_RS02630	COG0583	DNA-binding transcription factor activity
B7485_RS02635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7485_RS02640	COG0450	alkyl hydroperoxide reductase
B7485_RS02645	COG3634	alkyl hydroperoxide reductase activity
B7485_RS02655	COG1063	alcohol dehydrogenase
B7485_RS02660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7485_RS02665	COG3719	Belongs to the RNase T2 family
B7485_RS02685	COG3051	citrate lyase alpha subunit
B7485_RS02690	COG2301	Belongs to the HpcH HpaI aldolase family
B7485_RS02700	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
B7485_RS02710	COG0582	viral genome integration into host DNA
B7485_RS02715	COG0561	phosphatase activity
B7485_RS02725	COG4149	molybdate abc transporter
B7485_RS02730	COG0725	ABC transporter, periplasmic molybdate-binding protein
B7485_RS02740	COG2005	Transcriptional regulator
B7485_RS02740	COG3585	molybdate ion transport
B7485_RS02745	COG1119	ATPase activity
B7485_RS02750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7485_RS02755	COG1085	galactose-1-phosphate uridylyltransferase
B7485_RS02765	COG2017	converts alpha-aldose to the beta-anomer
B7485_RS02775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7485_RS02790	COG3201	nicotinamide mononucleotide transporter
B7485_RS02825	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
B7485_RS02830	COG2885	chlorophyll binding
B7485_RS02840	COG3064	Membrane
B7485_RS02845	COG0848	biopolymer transport protein
B7485_RS02850	COG0811	peptide transport
B7485_RS02855	COG0824	Thioesterase
B7485_RS02860	COG3790	cyd operon protein YbgE
B7485_RS02865	COG4890	Cyd operon protein YbgT
B7485_RS02870	COG1294	oxidase, subunit
B7485_RS02875	COG1271	oxidase subunit
B7485_RS02880	COG0383	alpha-mannosidase activity
B7485_RS02885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS02885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS02885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS02890	COG2188	Transcriptional regulator
B7485_RS02895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B7485_RS02905	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7485_RS02910	COG0567	Dehydrogenase, E1 component
B7485_RS02915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7485_RS02920	COG1053	succinate dehydrogenase
B7485_RS02925	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B7485_RS02930	COG2009	succinate dehydrogenase
B7485_RS02940	COG0372	Belongs to the citrate synthase family
B7485_RS02945	COG3539	Fimbrial protein
B7485_RS02965	COG3121	Chaperone
B7485_RS02975	COG3180	Ammonia monooxygenase
B7485_RS02995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B7485_RS03000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7485_RS03010	COG0415	Belongs to the DNA photolyase family
B7485_RS03015	COG3272	Protein of unknown function (DUF1722)
B7485_RS03030	COG3209	COG3209 Rhs family protein
B7485_RS03075	COG0745	RESPONSE REGULATOR receiver
B7485_RS03095	COG0531	amino acid
B7485_RS03100	COG0033	Phosphoglucomutase
B7485_RS03105	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
B7485_RS03110	COG0596	Alpha beta hydrolase
B7485_RS03120	COG0716	FMN binding
B7485_RS03130	COG0735	belongs to the Fur family
B7485_RS03150	COG1263	PTS System
B7485_RS03150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS03150	COG2190	(PTS) system
B7485_RS03160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B7485_RS03165	COG1846	Transcriptional regulator
B7485_RS03165	COG1940	carbohydrate kinase activity
B7485_RS03170	COG0647	UMP catabolic process
B7485_RS03175	COG0367	asparagine synthase
B7485_RS03220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7485_RS03230	COG1702	phosphate starvation-inducible protein PhoH
B7485_RS03240	COG4535	Mg2 and Co2 transporter CorC
B7485_RS03250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS03255	COG0765	amino acid transport
B7485_RS03260	COG0765	amino acid transport
B7485_RS03265	COG1126	abc transporter atp-binding protein
B7485_RS03280	COG2214	Heat shock protein DnaJ domain protein
B7485_RS03290	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B7485_RS03295	COG2214	Heat shock protein DnaJ domain protein
B7485_RS03305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B7485_RS03310	COG2888	peptidyl-tyrosine sulfation
B7485_RS03325	COG1466	dna polymerase III delta subunit
B7485_RS03335	COG0406	alpha-ribazole phosphatase activity
B7485_RS03340	COG0799	negative regulation of ribosome biogenesis
B7485_RS03350	COG0768	penicillin binding
B7485_RS03355	COG0772	Belongs to the SEDS family
B7485_RS03360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B7485_RS03365	COG1686	Belongs to the peptidase S11 family
B7485_RS03380	COG0583	DNA-binding transcription factor activity
B7485_RS03390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7485_RS03395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7485_RS03415	COG3069	C4-dicarboxylate transmembrane transporter activity
B7485_RS03430	COG3423	Transcriptional regulator
B7485_RS03495	COG1783	phage Terminase large subunit
B7485_RS03525	COG0582	viral genome integration into host DNA
B7485_RS03530	COG4677	pectinesterase activity
B7485_RS03535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7485_RS03540	COG0471	metal ion transport
B7485_RS03545	COG2828	Protein conserved in bacteria
B7485_RS03560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B7485_RS03590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7485_RS03605	COG3646	Phage regulatory protein
B7485_RS03630	COG1396	sequence-specific DNA binding
B7485_RS03665	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B7485_RS03815	COG1484	DNA-dependent DNA replication
B7485_RS03820	COG0305	Participates in initiation and elongation during chromosome replication
B7485_RS03870	COG3772	lysozyme
B7485_RS04070	COG1881	PFAM PEBP family protein
B7485_RS04075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7485_RS04090	COG2226	methyltransferase
B7485_RS04095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B7485_RS04105	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B7485_RS04115	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7485_RS04125	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B7485_RS04130	COG0314	molybdopterin synthase activity
B7485_RS04135	COG0670	Belongs to the BI1 family
B7485_RS04140	COG0670	Belongs to the BI1 family
B7485_RS04145	COG0392	lysyltransferase activity
B7485_RS04155	COG3568	Endonuclease Exonuclease Phosphatase
B7485_RS04165	COG0842	Transport permease protein
B7485_RS04170	COG0842	Transport permease protein
B7485_RS04175	COG1131	(ABC) transporter
B7485_RS04185	COG1309	transcriptional regulator
B7485_RS04205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7485_RS04210	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B7485_RS04220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7485_RS04235	COG3385	transposase activity
B7485_RS04260	COG1126	abc transporter atp-binding protein
B7485_RS04265	COG0765	amino acid transport
B7485_RS04270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS04280	COG5006	permease, DMT superfamily
B7485_RS04290	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B7485_RS04295	COG2194	sulfuric ester hydrolase activity
B7485_RS04305	COG1321	iron dependent repressor
B7485_RS04310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7485_RS04315	COG1376	ErfK ybiS ycfS ynhG family protein
B7485_RS04320	COG0488	(ABC) transporter
B7485_RS04330	COG0561	phosphatase activity
B7485_RS04335	COG1882	Formate acetyltransferase
B7485_RS04340	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B7485_RS04345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7485_RS04350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7485_RS04355	COG0303	'Molybdopterin
B7485_RS04360	COG1446	asparaginase
B7485_RS04385	COG2200	EAL domain
B7485_RS04390	COG2199	diguanylate cyclase activity
B7485_RS04405	COG2133	pyrroloquinoline quinone binding
B7485_RS04410	COG2133	pyrroloquinoline quinone binding
B7485_RS04415	COG0625	glutathione transferase activity
B7485_RS04420	COG1686	Belongs to the peptidase S11 family
B7485_RS04435	COG1349	DNA-binding transcription factor activity
B7485_RS04440	COG0671	phosphoesterase, PA-phosphatase related
B7485_RS04445	COG2814	Major facilitator Superfamily
B7485_RS04455	COG0561	phosphatase activity
B7485_RS04460	COG0738	Major facilitator superfamily
B7485_RS04465	COG3226	Transcriptional regulator
B7485_RS04480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7485_RS04490	COG0778	Nitroreductase
B7485_RS04505	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B7485_RS04510	COG3842	ATPase activity
B7485_RS04515	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7485_RS04520	COG1177	transmembrane transport
B7485_RS04535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS04540	COG4160	amino acid transport
B7485_RS04545	COG4215	(ABC) transporter
B7485_RS04550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS04555	COG1126	abc transporter atp-binding protein
B7485_RS04585	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7485_RS04590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7485_RS04595	COG0702	epimerase
B7485_RS04600	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
B7485_RS04605	COG0028	Belongs to the TPP enzyme family
B7485_RS04610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7485_RS04620	COG2431	L-lysine efflux transmembrane transporter activity
B7485_RS04640	COG3593	DNA synthesis involved in DNA repair
B7485_RS04645	COG2990	Protein conserved in bacteria
B7485_RS04650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS04660	COG1278	Cold shock
B7485_RS04670	COG0542	response to heat
B7485_RS04695	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B7485_RS04700	COG4988	ABC transporter
B7485_RS04705	COG0492	ferredoxin-NADP+ reductase activity
B7485_RS04710	COG1522	sequence-specific DNA binding
B7485_RS04725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7485_RS04740	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS04745	COG3302	dmso reductase anchor subunit
B7485_RS04750	COG1335	isochorismatase
B7485_RS04770	COG3436	PFAM IS66 Orf2 family protein
B7485_RS04805	COG0583	DNA-binding transcription factor activity
B7485_RS04820	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7485_RS04830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B7485_RS04835	COG1882	Formate acetyltransferase
B7485_RS04840	COG2116	formate transmembrane transporter activity
B7485_RS04845	COG1944	ATP diphosphatase activity
B7485_RS04865	COG3385	transposase activity
B7485_RS04870	COG0501	Belongs to the peptidase M48B family
B7485_RS04880	COG0539	negative regulation of cytoplasmic translation
B7485_RS04905	COG3214	Protein conserved in bacteria
B7485_RS04920	COG3173	Aminoglycoside phosphotransferase
B7485_RS04925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B7485_RS04930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B7485_RS04940	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
B7485_RS04950	COG3385	transposase activity
B7485_RS04955	COG2989	Protein conserved in bacteria
B7485_RS04960	COG3108	Peptidase M15
B7485_RS04965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7485_RS04970	COG1448	Aminotransferase
B7485_RS04990	COG0308	aminopeptidase N
B7485_RS05010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7485_RS05020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7485_RS05025	COG0431	NADPH-dependent FMN reductase
B7485_RS05045	COG3188	usher protein
B7485_RS05050	COG3539	Fimbrial protein
B7485_RS05055	COG3539	Fimbrial protein
B7485_RS05060	COG3539	Fimbrial protein
B7485_RS05080	COG3217	Mosc domain protein beta barrel domain protein
B7485_RS05080	COG0633	Ferredoxin
B7485_RS05090	COG0488	(ABC) transporter
B7485_RS05095	COG2995	paraquat-inducible protein a
B7485_RS05100	COG3008	intermembrane lipid transfer
B7485_RS05100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7485_RS05105	COG3009	Protein conserved in bacteria
B7485_RS05110	COG3130	regulation of translation
B7485_RS05120	COG1067	ATP-dependent peptidase activity
B7485_RS05140	COG3070	regulator of competence-specific genes
B7485_RS05150	COG1289	transmembrane transporter activity
B7485_RS05155	COG3304	Inner membrane component domain
B7485_RS05160	COG0210	DNA helicase
B7485_RS05175	COG1832	CoA-binding protein
B7485_RS05190	COG1254	Belongs to the acylphosphatase family
B7485_RS05195	COG2920	part of a sulfur-relay system
B7485_RS05200	COG0670	Belongs to the BI1 family
B7485_RS05210	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
B7485_RS05215	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B7485_RS05220	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
B7485_RS05225	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B7485_RS05230	COG1999	signal sequence binding
B7485_RS05235	COG1773	rubredoxin
B7485_RS05240	COG1271	oxidase subunit
B7485_RS05245	COG1294	oxidase, subunit
B7485_RS05260	COG0489	protein tyrosine kinase activity
B7485_RS05260	COG3206	protein involved in exopolysaccharide biosynthesis
B7485_RS05265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7485_RS05270	COG1596	polysaccharide export
B7485_RS05275	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS05295	COG1278	Cold shock
B7485_RS05310	COG1879	ABC-type sugar transport system periplasmic component
B7485_RS05315	COG0745	RESPONSE REGULATOR receiver
B7485_RS05320	COG3005	denitrification pathway
B7485_RS05325	COG0243	molybdopterin cofactor binding
B7485_RS05375	COG3729	General stress protein
B7485_RS05380	COG2233	PERMEase
B7485_RS05420	COG1309	transcriptional regulator
B7485_RS05440	COG2822	iron ion transport
B7485_RS05450	COG1702	phosphate starvation-inducible protein PhoH
B7485_RS05455	COG3658	cytochrome
B7485_RS05485	COG3381	protein complex oligomerization
B7485_RS05510	COG2197	response regulator
B7485_RS05550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7485_RS05565	COG2943	transferase activity, transferring hexosyl groups
B7485_RS05655	COG1560	Kdo2-lipid A biosynthetic process
B7485_RS05670	COG3038	cytochrome b561
B7485_RS05705	COG2999	glutathione oxidoreductase activity
B7485_RS05715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7485_RS05725	COG0673	inositol 2-dehydrogenase activity
B7485_RS05730	COG0728	peptidoglycan biosynthetic process
B7485_RS05735	COG3418	PFAM FlgN family protein
B7485_RS05740	COG2747	anti-sigma28 factor FlgM
B7485_RS05745	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
B7485_RS05750	COG1815	bacterial-type flagellum-dependent cell motility
B7485_RS05760	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B7485_RS05765	COG1749	Flagellar hook protein flgE
B7485_RS05775	COG4786	Flagellar basal body rod
B7485_RS05790	COG3951	Flagellar rod assembly protein muramidase FlgJ
B7485_RS05790	COG1705	Flagellar rod assembly protein muramidase FlgJ
B7485_RS05800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7485_RS05805	COG1530	ribonuclease E activity
B7485_RS05815	COG0564	pseudouridine synthase activity
B7485_RS05820	COG0424	maF-like protein
B7485_RS05825	COG1399	metal-binding, possibly nucleic acid-binding protein
B7485_RS05845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B7485_RS05850	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS05860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7485_RS05865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7485_RS05870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7485_RS05880	COG0470	DNA polymerase III
B7485_RS05885	COG0084	hydrolase, TatD family'
B7485_RS05890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS05890	COG1263	PTS System
B7485_RS05905	COG0537	adenosine 5'-monophosphoramidase activity
B7485_RS05910	COG5633	Lipoprotein
B7485_RS05915	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
B7485_RS05935	COG1252	NADH dehydrogenase
B7485_RS05945	COG1309	transcriptional regulator
B7485_RS05955	COG1376	ErfK ybiS ycfS ynhG family protein
B7485_RS05955	COG1388	LysM domain
B7485_RS05960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B7485_RS05965	COG4763	Acyl-transferase
B7485_RS05970	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7485_RS05980	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7485_RS05995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B7485_RS06000	COG1177	transmembrane transport
B7485_RS06010	COG3842	ATPase activity
B7485_RS06020	COG2850	peptidyl-arginine hydroxylation
B7485_RS06140	COG4626	Terminase
B7485_RS06140	COG1802	Transcriptional regulator
B7485_RS06160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7485_RS06185	COG0538	isocitrate dehydrogenase activity
B7485_RS06195	COG2200	EAL domain
B7485_RS06245	COG2894	cell division
B7485_RS06290	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7485_RS06305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B7485_RS06310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7485_RS06330	COG2719	SpoVR family
B7485_RS06340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7485_RS06355	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7485_RS06365	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B7485_RS06380	COG0157	Belongs to the NadC ModD family
B7485_RS06385	COG0500	methyltransferase
B7485_RS06390	COG1120	ATPase activity
B7485_RS06395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7485_RS06400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7485_RS06425	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
B7485_RS06425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS06425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7485_RS06430	COG1461	Dihydroxyacetone kinase
B7485_RS06435	COG2376	Dihydroxyacetone kinase
B7485_RS06440	COG3284	Transcriptional regulator
B7485_RS06445	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS06450	COG0012	GTP binding
B7485_RS06465	COG0659	secondary active sulfate transmembrane transporter activity
B7485_RS06470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7485_RS06495	COG2890	protein-(glutamine-N5) methyltransferase activity
B7485_RS06500	COG3094	Invasion gene expression up-regulator, SirB
B7485_RS06520	COG0387	Pfam Sodium calcium exchanger
B7485_RS06525	COG4572	Cation transport regulator
B7485_RS06530	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B7485_RS06535	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B7485_RS06540	COG4932	domain protein
B7485_RS06545	COG2197	response regulator
B7485_RS06550	COG3850	Histidine kinase
B7485_RS06555	COG2223	nitrite transmembrane transporter activity
B7485_RS06560	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B7485_RS06565	COG1140	nitrate reductase beta subunit
B7485_RS06570	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B7485_RS06575	COG2181	nitrate reductase activity
B7485_RS06590	COG0788	formyltetrahydrofolate deformylase activity
B7485_RS06600	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7485_RS06605	COG0745	RESPONSE REGULATOR receiver
B7485_RS06610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7485_RS06620	COG1435	thymidine kinase activity
B7485_RS06625	COG3385	transposase activity
B7485_RS06630	COG1454	alcohol dehydrogenase
B7485_RS06630	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS06635	COG2095	MarC family integral membrane protein
B7485_RS06640	COG4166	transmembrane transport
B7485_RS06645	COG0601	transmembrane transport
B7485_RS06650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7485_RS06655	COG0444	Belongs to the ABC transporter superfamily
B7485_RS06660	COG4608	Belongs to the ABC transporter superfamily
B7485_RS06680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7485_RS06690	COG2350	Protein conserved in bacteria
B7485_RS06695	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
B7485_RS06700	COG1607	acyl-coa hydrolase
B7485_RS06720	COG3047	cAMP biosynthetic process
B7485_RS06725	COG3685	Protein conserved in bacteria
B7485_RS06730	COG3685	Protein conserved in bacteria
B7485_RS06735	COG3729	General stress protein
B7485_RS06750	COG0134	indole-3-glycerol-phosphate synthase activity
B7485_RS06750	COG0135	phosphoribosylanthranilate isomerase activity
B7485_RS06755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7485_RS06755	COG0512	Glutamine amidotransferase of anthranilate synthase
B7485_RS06760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7485_RS06770	COG0613	PHP domain protein
B7485_RS06775	COG0009	L-threonylcarbamoyladenylate synthase
B7485_RS06785	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
B7485_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS06795	COG0616	signal peptide processing
B7485_RS06805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7485_RS06810	COG0583	DNA-binding transcription factor activity
B7485_RS06830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7485_RS06840	COG0671	phosphoesterase, PA-phosphatase related
B7485_RS06845	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
B7485_RS06850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B7485_RS06860	COG0023	Translation Initiation Factor
B7485_RS06870	COG1349	DNA-binding transcription factor activity
B7485_RS06895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7485_RS06895	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7485_RS06900	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B7485_RS06905	COG2852	Protein conserved in bacteria
B7485_RS06910	COG4172	Belongs to the ABC transporter superfamily
B7485_RS06915	COG4172	Belongs to the ABC transporter superfamily
B7485_RS06920	COG4171	peptide transport system, permease
B7485_RS06925	COG4168	peptide transport system, permease
B7485_RS06930	COG4166	transmembrane transport
B7485_RS06940	COG0531	amino acid
B7485_RS06950	COG0174	glutamine synthetase
B7485_RS06960	COG1396	sequence-specific DNA binding
B7485_RS06960	COG1917	Cupin 2, conserved barrel domain protein
B7485_RS06965	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS06970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7485_RS06975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7485_RS06980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B7485_RS06985	COG1842	Phage shock protein A
B7485_RS06995	COG1983	PspC domain protein
B7485_RS07005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7485_RS07010	COG0366	Alpha amylase catalytic
B7485_RS07030	COG1175	transmembrane transport
B7485_RS07035	COG0395	ABC-type sugar transport system, permease component
B7485_RS07040	COG1063	alcohol dehydrogenase
B7485_RS07055	COG1554	hydrolase, family 65, central catalytic
B7485_RS07060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS07075	COG1609	Transcriptional regulator
B7485_RS07080	COG3106	COG3106 Predicted ATPase
B7485_RS07090	COG3283	Transcriptional regulator of aromatic amino acids metabolism
B7485_RS07095	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B7485_RS07100	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS07105	COG2866	Carboxypeptidase
B7485_RS07110	COG0702	epimerase
B7485_RS07115	COG1073	alpha beta
B7485_RS07120	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS07130	COG3756	Protein conserved in bacteria
B7485_RS07135	COG1484	DNA-dependent DNA replication
B7485_RS07240	COG4974	Belongs to the 'phage' integrase family
B7485_RS07285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7485_RS07290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7485_RS07295	COG1121	(ABC) transporter
B7485_RS07305	COG0582	viral genome integration into host DNA
B7485_RS07460	COG1956	GAF domain-containing protein
B7485_RS07470	COG0793	Belongs to the peptidase S41A family
B7485_RS07480	COG2814	Major facilitator Superfamily
B7485_RS07485	COG1414	Transcriptional regulator
B7485_RS07515	COG2226	methyltransferase
B7485_RS07535	COG3716	PTS system mannose fructose sorbose family IID component
B7485_RS07540	COG3715	PTS system
B7485_RS07545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS07545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS07550	COG1253	flavin adenine dinucleotide binding
B7485_RS07555	COG2200	EAL domain
B7485_RS07560	COG1760	l-serine dehydratase
B7485_RS07570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7485_RS07585	COG0251	oxidation-reduction process
B7485_RS07590	COG1199	ATP-dependent helicase activity
B7485_RS07595	COG1214	PFAM Peptidase M22, glycoprotease
B7485_RS07600	COG3065	identical protein binding
B7485_RS07605	COG0318	PFAM AMP-dependent synthetase and ligase
B7485_RS07610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B7485_RS07615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7485_RS07620	COG4638	Rieske (2fe-2S)
B7485_RS07645	COG3713	MltA-interacting MipA family protein
B7485_RS07650	COG0656	L-ascorbic acid biosynthetic process
B7485_RS07655	COG0676	glucose-6-phosphate 1-epimerase activity
B7485_RS07660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7485_RS07670	COG3139	Protein of unknown function (DUF1315)
B7485_RS07675	COG1063	alcohol dehydrogenase
B7485_RS07680	COG2271	Major facilitator Superfamily
B7485_RS07690	COG0191	fructose-bisphosphate aldolase activity
B7485_RS07695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS07700	COG0667	Aldo Keto reductase
B7485_RS07705	COG1349	DNA-binding transcription factor activity
B7485_RS07710	COG2814	Major facilitator Superfamily
B7485_RS07715	COG1335	isochorismatase
B7485_RS07720	COG0252	asparaginase activity
B7485_RS07725	COG0616	signal peptide processing
B7485_RS07730	COG0778	Nitroreductase
B7485_RS07740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7485_RS07760	COG0494	nUDIX hydrolase
B7485_RS07765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7485_RS07775	COG4136	ATPase activity
B7485_RS07790	COG3385	transposase activity
B7485_RS07795	COG4134	Bacterial extracellular solute-binding protein
B7485_RS07800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7485_RS07805	COG0398	Pfam SNARE associated Golgi protein
B7485_RS07820	COG0708	Exodeoxyribonuclease III
B7485_RS07850	COG3678	ATP-independent chaperone mediated protein folding
B7485_RS07870	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS07880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7485_RS07885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7485_RS07890	COG1447	Phosphotransferase system cellobiose-specific component IIA
B7485_RS07900	COG1486	melibiose metabolic process
B7485_RS07910	COG0753	catalase activity
B7485_RS07930	COG1988	membrane-bound metal-dependent
B7485_RS07935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS07945	COG3001	Fructosamine kinase
B7485_RS07955	COG1105	Belongs to the carbohydrate kinase PfkB family
B7485_RS07965	COG3137	Salt-induced outer membrane protein
B7485_RS08035	COG0386	Belongs to the glutathione peroxidase family
B7485_RS08045	COG0791	NLP P60 protein
B7485_RS08050	COG2200	EAL domain
B7485_RS08060	COG4256	Hemin uptake protein
B7485_RS08075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7485_RS08075	COG0574	Belongs to the PEP-utilizing enzyme family
B7485_RS08080	COG0318	PFAM AMP-dependent synthetase and ligase
B7485_RS08085	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B7485_RS08090	COG0644	oxidoreductase
B7485_RS08100	COG2086	electron transfer activity
B7485_RS08105	COG1917	Cupin 2, conserved barrel domain protein
B7485_RS08105	COG2207	Transcriptional regulator
B7485_RS08115	COG3119	arylsulfatase activity
B7485_RS08155	COG3077	Addiction module antitoxin, RelB DinJ family
B7485_RS08160	COG2026	Addiction module toxin, RelE StbE family
B7485_RS08180	COG1403	HNH endonuclease
B7485_RS08185	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B7485_RS08190	COG0484	heat shock protein binding
B7485_RS08240	COG0246	Mannitol dehydrogenase
B7485_RS08250	COG1802	Transcriptional regulator
B7485_RS08260	COG0339	signal peptide processing
B7485_RS08265	COG1546	Belongs to the CinA family
B7485_RS08285	COG2814	Major facilitator Superfamily
B7485_RS08290	COG0697	spore germination
B7485_RS08300	COG4977	sequence-specific DNA binding
B7485_RS08305	COG1846	Transcriptional regulator
B7485_RS08325	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS08340	COG2199	diguanylate cyclase activity
B7485_RS08360	COG3781	membrane
B7485_RS08425	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS08485	COG0243	molybdopterin cofactor binding
B7485_RS08500	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS08505	COG3302	dmso reductase anchor subunit
B7485_RS08510	COG3381	protein complex oligomerization
B7485_RS08520	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B7485_RS08525	COG1940	carbohydrate kinase activity
B7485_RS08530	COG0583	DNA-binding transcription factor activity
B7485_RS08550	COG3591	Belongs to the peptidase S1B family
B7485_RS08570	COG0628	permease
B7485_RS08575	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B7485_RS08580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B7485_RS08590	COG0531	amino acid
B7485_RS08600	COG3136	membrane protein required for alginate biosynthesis
B7485_RS08605	COG0745	RESPONSE REGULATOR receiver
B7485_RS08610	COG1823	symporter activity
B7485_RS08615	COG2205	protein histidine kinase activity
B7485_RS08630	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS08630	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS08640	COG5339	Protein conserved in bacteria
B7485_RS08655	COG3250	beta-galactosidase activity
B7485_RS08660	COG1309	transcriptional regulator
B7485_RS08675	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS08680	COG1609	Transcriptional regulator
B7485_RS08685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS08685	COG1263	PTS System
B7485_RS08690	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B7485_RS08700	COG0673	inositol 2-dehydrogenase activity
B7485_RS08740	COG4659	FMN binding
B7485_RS08750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7485_RS08760	COG3104	oligopeptide transport
B7485_RS08765	COG0625	glutathione transferase activity
B7485_RS08805	COG3133	Outer membrane lipoprotein
B7485_RS08820	COG1566	PFAM secretion protein HlyD family protein
B7485_RS08830	COG2032	superoxide dismutase activity
B7485_RS08835	COG4989	oxidoreductase activity
B7485_RS08840	COG3313	Fe-S protein
B7485_RS08845	COG1309	transcriptional regulator
B7485_RS08850	COG1902	pentaerythritol trinitrate reductase activity
B7485_RS08855	COG0346	lactoylglutathione lyase activity
B7485_RS08870	COG0675	Transposase, IS605 OrfB family
B7485_RS08880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B7485_RS08885	COG0791	NLP P60 protein
B7485_RS08890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7485_RS08895	COG2814	Major facilitator Superfamily
B7485_RS08910	COG0583	DNA-binding transcription factor activity
B7485_RS08915	COG2814	Major facilitator Superfamily
B7485_RS08920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7485_RS08925	COG0307	riboflavin synthase, alpha
B7485_RS08935	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS08955	COG4529	Protein conserved in bacteria
B7485_RS08965	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
B7485_RS08970	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS08985	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS09000	COG0469	pyruvate kinase activity
B7485_RS09005	COG4238	major outer membrane lipoprotein
B7485_RS09010	COG1376	ErfK ybiS ycfS ynhG family protein
B7485_RS09025	COG0719	Fe-S assembly protein
B7485_RS09030	COG0396	ATPase activity
B7485_RS09035	COG0719	Fe-S assembly protein
B7485_RS09040	COG0316	Belongs to the HesB IscA family
B7485_RS09050	COG2050	protein possibly involved in aromatic compounds catabolism
B7485_RS09055	COG0277	FAD linked oxidase domain protein
B7485_RS09055	COG0247	lactate metabolic process
B7485_RS09060	COG0628	permease
B7485_RS09075	COG0738	Major facilitator superfamily
B7485_RS09080	COG2271	Major facilitator Superfamily
B7485_RS09105	COG0641	radical SAM
B7485_RS09120	COG4771	TonB-dependent receptor
B7485_RS09125	COG0612	Peptidase, M16
B7485_RS09135	COG0076	glutamate decarboxylase activity
B7485_RS09140	COG0531	amino acid
B7485_RS09145	COG1649	PFAM Uncharacterised BCR, COG1649
B7485_RS09165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7485_RS09170	COG0444	Belongs to the ABC transporter superfamily
B7485_RS09180	COG1764	response to oxidative stress
B7485_RS09200	COG3093	addiction module antidote protein HigA
B7485_RS09205	COG2864	formate dehydrogenase
B7485_RS09210	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS09220	COG0697	spore germination
B7485_RS09235	COG4886	Leucine-rich repeat (LRR) protein
B7485_RS09260	COG1140	nitrate reductase beta subunit
B7485_RS09285	COG1802	Transcriptional regulator
B7485_RS09290	COG2130	NADP-dependent
B7485_RS09305	COG1247	-acetyltransferase
B7485_RS09310	COG3238	Protein conserved in bacteria
B7485_RS09340	COG1177	transmembrane transport
B7485_RS09390	COG0500	methyltransferase
B7485_RS09395	COG1275	C4-dicarboxylate transporter malic acid transport protein
B7485_RS09400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B7485_RS09405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7485_RS09410	COG2841	Protein conserved in bacteria
B7485_RS09420	COG5383	Protein conserved in bacteria
B7485_RS09425	COG0583	DNA-binding transcription factor activity
B7485_RS09430	COG0840	transmembrane signaling receptor activity
B7485_RS09470	COG3038	cytochrome b561
B7485_RS09475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7485_RS09480	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS09510	COG1643	Atp-dependent helicase
B7485_RS09535	COG2267	carboxylic ester hydrolase activity
B7485_RS09540	COG4589	Belongs to the CDS family
B7485_RS09545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7485_RS09575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7485_RS09580	COG2911	Protein conserved in bacteria
B7485_RS09590	COG3784	Protein of unknown function (DUF1318)
B7485_RS09605	COG3042	response to heat
B7485_RS09610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7485_RS09610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B7485_RS09610	COG1013	pyruvate-flavodoxin oxidoreductase activity
B7485_RS09610	COG0674	pyruvate-flavodoxin oxidoreductase activity
B7485_RS09630	COG0589	response to stress
B7485_RS09640	COG0513	Belongs to the DEAD box helicase family
B7485_RS09655	COG2840	Smr protein MutS2
B7485_RS09695	COG2207	Transcriptional regulator
B7485_RS09705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7485_RS09710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7485_RS09715	COG0589	response to stress
B7485_RS09745	COG0668	transmembrane transport
B7485_RS09750	COG4166	transmembrane transport
B7485_RS09820	COG2372	response to copper ion
B7485_RS09835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7485_RS09840	COG1770	oligopeptidase
B7485_RS09845	COG2979	Protein of unknown function (DUF533)
B7485_RS09865	COG0800	Aldolase
B7485_RS09870	COG0129	dihydroxy-acid dehydratase activity
B7485_RS09875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B7485_RS09880	COG1737	Transcriptional regulator
B7485_RS09885	COG0469	pyruvate kinase activity
B7485_RS09895	COG0739	heme binding
B7485_RS09900	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
B7485_RS09910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7485_RS09940	COG0217	transcriptional regulatory protein
B7485_RS09945	COG0494	nUDIX hydrolase
B7485_RS09955	COG1335	isochorismatase
B7485_RS09960	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS10070	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS10105	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B7485_RS10165	COG1801	Protein of unknown function DUF72
B7485_RS10170	COG3788	relative of glutathione S-transferase, MAPEG superfamily
B7485_RS10185	COG0243	molybdopterin cofactor binding
B7485_RS10190	COG3005	denitrification pathway
B7485_RS10200	COG3102	Protein conserved in bacteria
B7485_RS10210	COG3755	Protein conserved in bacteria
B7485_RS10225	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7485_RS10230	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7485_RS10235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7485_RS10240	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B7485_RS10270	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B7485_RS10275	COG0745	RESPONSE REGULATOR receiver
B7485_RS10285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7485_RS10290	COG0840	transmembrane signaling receptor activity
B7485_RS10295	COG0840	transmembrane signaling receptor activity
B7485_RS10300	COG0835	chemotaxis
B7485_RS10310	COG1360	Flagellar Motor Protein
B7485_RS10315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B7485_RS10335	COG0589	response to stress
B7485_RS10345	COG1877	trehalose-phosphatase activity
B7485_RS10350	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7485_RS10365	COG1528	Iron-storage protein
B7485_RS10385	COG1528	Iron-storage protein
B7485_RS10395	COG0814	amino acid
B7485_RS10400	COG3012	SEC-C Motif Domain Protein
B7485_RS10400	COG3318	Belongs to the UPF0149 family
B7485_RS10430	COG2197	response regulator
B7485_RS10445	COG2197	response regulator
B7485_RS10450	COG1126	abc transporter atp-binding protein
B7485_RS10455	COG0765	amino acid transport
B7485_RS10465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS10475	COG1191	sigma factor activity
B7485_RS10485	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B7485_RS10490	COG1516	flagellar protein fliS
B7485_RS10500	COG0366	Alpha amylase catalytic
B7485_RS10510	COG2391	methyltransferase activity
B7485_RS10515	COG0425	Belongs to the sulfur carrier protein TusA family
B7485_RS10550	COG1881	PFAM PEBP family protein
B7485_RS10555	COG2076	Multidrug Resistance protein
B7485_RS10580	COG1317	bacterial-type flagellum organization
B7485_RS10585	COG1157	protein secretion by the type III secretion system
B7485_RS10595	COG3144	bacterial-type flagellum assembly
B7485_RS10600	COG1580	Controls the rotational direction of flagella during chemotaxis
B7485_RS10605	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7485_RS10610	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7485_RS10615	COG3190	flagellar
B7485_RS10620	COG1338	Plays a role in the flagellum-specific transport system
B7485_RS10625	COG1987	bacterial-type flagellum assembly
B7485_RS10630	COG1684	flagellar biosynthetic protein fliR
B7485_RS10635	COG2197	response regulator
B7485_RS10665	COG5475	Uncharacterized small protein (DUF2158)
B7485_RS10670	COG2354	Protein conserved in bacteria
B7485_RS10675	COG0697	spore germination
B7485_RS10680	COG3727	T/G mismatch-specific endonuclease activity
B7485_RS10685	COG0270	DNA (cytosine-5-)-methyltransferase activity
B7485_RS10730	COG0745	RESPONSE REGULATOR receiver
B7485_RS10735	COG2351	hydroxyisourate hydrolase activity
B7485_RS10750	COG3443	Belongs to the bacterial solute-binding protein 9 family
B7485_RS10765	COG0500	methyltransferase
B7485_RS10835	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B7485_RS10840	COG1403	HNH endonuclease
B7485_RS10910	COG0477	Major facilitator Superfamily
B7485_RS11070	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B7485_RS11075	COG1403	HNH endonuclease
B7485_RS11145	COG0477	Major facilitator Superfamily
B7485_RS11180	COG4372	Transposase
B7485_RS11210	COG0582	viral genome integration into host DNA
B7485_RS11215	COG2925	Exonuclease
B7485_RS11220	COG0425	Belongs to the sulfur carrier protein TusA family
B7485_RS11225	COG2391	methyltransferase activity
B7485_RS11230	COG0531	amino acid
B7485_RS11240	COG0583	DNA-binding transcription factor activity
B7485_RS11245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7485_RS11250	COG4115	mRNA cleavage
B7485_RS11405	COG0438	transferase activity, transferring glycosyl groups
B7485_RS11410	COG2327	Polysaccharide pyruvyl transferase
B7485_RS11415	COG2244	polysaccharide biosynthetic process
B7485_RS11420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7485_RS11425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7485_RS11430	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
B7485_RS11430	COG0662	Cupin 2, conserved barrel domain protein
B7485_RS11435	COG0297	glycogen (starch) synthase activity
B7485_RS11440	COG1051	belongs to the nudix hydrolase family
B7485_RS11450	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B7485_RS11455	COG0110	maltose O-acetyltransferase activity
B7485_RS11475	COG0438	transferase activity, transferring glycosyl groups
B7485_RS11480	COG1045	serine acetyltransferase
B7485_RS11485	COG0463	Glycosyl transferase, family 2
B7485_RS11490	COG0489	protein tyrosine kinase activity
B7485_RS11490	COG3206	protein involved in exopolysaccharide biosynthesis
B7485_RS11495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7485_RS11500	COG1596	polysaccharide export
B7485_RS11510	COG2982	Protein involved in outer membrane biogenesis
B7485_RS11520	COG0572	uridine kinase
B7485_RS11530	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS11535	COG4245	von Willebrand factor, type A
B7485_RS11540	COG0631	protein serine/threonine phosphatase activity
B7485_RS11545	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
B7485_RS11550	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
B7485_RS11560	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B7485_RS11570	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS11595	COG2205	protein histidine kinase activity
B7485_RS11600	COG0745	RESPONSE REGULATOR receiver
B7485_RS11610	COG0826	peptidase U32
B7485_RS11635	COG1063	alcohol dehydrogenase
B7485_RS11640	COG3775	system Galactitol-specific IIC component
B7485_RS11645	COG3414	Phosphotransferase system galactitol-specific IIB component
B7485_RS11650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS11665	COG1830	Aldolase
B7485_RS11670	COG2211	Major facilitator Superfamily
B7485_RS11680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS11685	COG2188	Transcriptional regulator
B7485_RS11690	COG3757	hydrolase, family 25
B7485_RS11695	COG0351	phosphomethylpyrimidine kinase
B7485_RS11715	COG5455	response to cobalt ion
B7485_RS11725	COG3188	usher protein
B7485_RS11730	COG3121	Chaperone
B7485_RS11735	COG3539	Fimbrial protein
B7485_RS11745	COG0489	protein tyrosine kinase activity
B7485_RS11790	COG0714	Associated with various cellular activities
B7485_RS11795	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B7485_RS11800	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B7485_RS11805	COG4715	Zinc finger, swim domain protein
B7485_RS11815	COG4808	Protein conserved in bacteria
B7485_RS11820	COG4807	Protein conserved in bacteria
B7485_RS11830	COG3275	phosphorelay sensor kinase activity
B7485_RS11835	COG3385	transposase activity
B7485_RS11855	COG0500	methyltransferase
B7485_RS11875	COG5301	cellulose 1,4-beta-cellobiosidase activity
B7485_RS11895	COG0582	viral genome integration into host DNA
B7485_RS11900	COG0789	Transcriptional regulator
B7485_RS11920	COG1174	glycine betaine transport
B7485_RS11925	COG1125	glycine betaine transport
B7485_RS11930	COG1174	glycine betaine transport
B7485_RS11935	COG1732	Glycine betaine
B7485_RS11940	COG1472	Belongs to the glycosyl hydrolase 3 family
B7485_RS11945	COG0277	FAD linked oxidase domain protein
B7485_RS11950	COG1686	Belongs to the peptidase S11 family
B7485_RS11960	COG0586	Pfam SNARE associated Golgi protein
B7485_RS11990	COG1346	cytolysis
B7485_RS12000	COG2949	membrane
B7485_RS12010	COG0493	'glutamate synthase
B7485_RS12020	COG4211	Belongs to the binding-protein-dependent transport system permease family
B7485_RS12025	COG1129	ABC transporter
B7485_RS12030	COG1879	ABC-type sugar transport system periplasmic component
B7485_RS12035	COG1609	Transcriptional regulator
B7485_RS12040	COG2311	Membrane
B7485_RS12055	COG4771	TonB-dependent receptor
B7485_RS12065	COG0833	amino acid
B7485_RS12070	COG0583	DNA-binding transcription factor activity
B7485_RS12075	COG2855	membrane
B7485_RS12085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS12085	COG1522	sequence-specific DNA binding
B7485_RS12090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7485_RS12105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7485_RS12110	COG2313	pseudouridylate synthase activity
B7485_RS12115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS12120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS12120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS12120	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B7485_RS12125	COG1105	Belongs to the carbohydrate kinase PfkB family
B7485_RS12130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS12130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS12135	COG2814	Major facilitator Superfamily
B7485_RS12155	COG0246	Mannitol dehydrogenase
B7485_RS12160	COG0523	cobalamin synthesis protein
B7485_RS12165	COG0671	phosphoesterase, PA-phosphatase related
B7485_RS12170	COG0791	NLP P60 protein
B7485_RS12175	COG2200	EAL domain
B7485_RS12180	COG4166	transmembrane transport
B7485_RS12185	COG4174	ABC transporter (Permease)
B7485_RS12190	COG4239	(ABC) transporter, permease
B7485_RS12195	COG4172	Belongs to the ABC transporter superfamily
B7485_RS12205	COG2814	Major facilitator Superfamily
B7485_RS12210	COG1187	pseudouridine synthase activity
B7485_RS12215	COG1061	Type III restriction enzyme res subunit
B7485_RS12235	COG3083	sulfuric ester hydrolase activity
B7485_RS12245	COG0582	viral genome integration into host DNA
B7485_RS12295	COG2963	transposase activity
B7485_RS12300	COG2826	transposase and inactivated derivatives, IS30 family
B7485_RS12320	COG3344	reverse transcriptase
B7485_RS12345	COG2246	polysaccharide biosynthetic process
B7485_RS12350	COG0463	Glycosyl transferase, family 2
B7485_RS12390	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS12395	COG2197	response regulator
B7485_RS12400	COG4235	cytochrome complex assembly
B7485_RS12400	COG3088	subunit of a heme lyase
B7485_RS12405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7485_RS12410	COG1138	Cytochrome C-type biogenesis protein
B7485_RS12420	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7485_RS12425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7485_RS12430	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7485_RS12440	COG3005	denitrification pathway
B7485_RS12445	COG3043	anaerobic respiration
B7485_RS12450	COG0348	domain, Protein
B7485_RS12455	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS12465	COG3062	negative regulation of establishment of protein localization
B7485_RS12470	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS12470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS12490	COG4615	Cyclic peptide transporter
B7485_RS12495	COG3145	DNA-N1-methyladenine dioxygenase activity
B7485_RS12500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7485_RS12500	COG2169	Transcriptional regulator
B7485_RS12505	COG1477	protein flavinylation
B7485_RS12515	COG0642	Histidine kinase
B7485_RS12515	COG2198	Histidine kinase
B7485_RS12520	COG2197	response regulator
B7485_RS12525	COG0784	Response regulator, receiver
B7485_RS12525	COG2205	protein histidine kinase activity
B7485_RS12530	COG4676	Protein conserved in bacteria
B7485_RS12560	COG3234	Protein of unknown function (DUF1175)
B7485_RS12570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7485_RS12580	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS12585	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS12600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7485_RS12605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7485_RS12610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7485_RS12615	COG3642	lipopolysaccharide core region biosynthetic process
B7485_RS12625	COG0584	glycerophosphoryl diester phosphodiesterase
B7485_RS12630	COG2271	Major facilitator Superfamily
B7485_RS12635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7485_RS12645	COG0247	lactate metabolic process
B7485_RS12650	COG5464	transposase or invertase
B7485_RS12720	COG0318	PFAM AMP-dependent synthetase and ligase
B7485_RS12730	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B7485_RS12745	COG1169	isochorismate synthase
B7485_RS12750	COG4575	ribosome binding
B7485_RS12755	COG2153	protein acetylation
B7485_RS12795	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7485_RS12800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7485_RS12810	COG0839	Belongs to the complex I subunit 6 family
B7485_RS12830	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B7485_RS12835	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B7485_RS12855	COG0583	DNA-binding transcription factor activity
B7485_RS12860	COG0436	Aminotransferase
B7485_RS12870	COG0471	metal ion transport
B7485_RS12870	COG0490	domain, Protein
B7485_RS12875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS12890	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7485_RS12895	COG0857	belongs to the CobB CobQ family
B7485_RS12895	COG0280	phosphate acetyltransferase
B7485_RS12900	COG1288	antiporter activity
B7485_RS12910	COG0622	Phosphoesterase
B7485_RS12915	COG0625	glutathione transferase activity
B7485_RS12920	COG0625	glutathione transferase activity
B7485_RS12925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B7485_RS12930	COG1090	epimerase
B7485_RS12935	COG5464	transposase or invertase
B7485_RS12940	COG4598	ABC transporter
B7485_RS12945	COG4160	amino acid transport
B7485_RS12950	COG4215	(ABC) transporter
B7485_RS12955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS12965	COG0163	prenyltransferase activity
B7485_RS12970	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B7485_RS12975	COG1286	toxin biosynthetic process
B7485_RS12980	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
B7485_RS12985	COG0285	dihydrofolate synthase activity
B7485_RS12995	COG0586	Pfam SNARE associated Golgi protein
B7485_RS13005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B7485_RS13025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7485_RS13040	COG3101	peptidyl-lysine hydroxylation
B7485_RS13045	COG0730	response to heat
B7485_RS13075	COG3539	Fimbrial protein
B7485_RS13080	COG3539	Fimbrial protein
B7485_RS13090	COG3539	Fimbrial protein
B7485_RS13105	COG3539	Fimbrial protein
B7485_RS13115	COG2062	phosphohistidine phosphatase, SixA
B7485_RS13130	COG3691	Protein conserved in bacteria
B7485_RS13150	COG2116	formate transmembrane transporter activity
B7485_RS13160	COG0582	viral genome integration into host DNA
B7485_RS13195	COG0477	Major facilitator Superfamily
B7485_RS13200	COG1566	PFAM secretion protein HlyD family protein
B7485_RS13205	COG2197	response regulator
B7485_RS13210	COG2198	Histidine kinase
B7485_RS13210	COG2205	protein histidine kinase activity
B7485_RS13210	COG0784	Response regulator, receiver
B7485_RS13210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS13215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7485_RS13220	COG0679	Auxin Efflux Carrier
B7485_RS13225	COG0028	Belongs to the TPP enzyme family
B7485_RS13250	COG1560	Kdo2-lipid A biosynthetic process
B7485_RS13265	COG0436	Aminotransferase
B7485_RS13275	COG3279	Response regulator of the LytR AlgR family
B7485_RS13280	COG2207	Transcriptional regulator
B7485_RS13290	COG1363	Peptidase, m42
B7485_RS13300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS13330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7485_RS13340	COG2199	diguanylate cyclase activity
B7485_RS13340	COG2200	EAL domain
B7485_RS13355	COG3415	Transposase
B7485_RS13360	COG3415	Transposase
B7485_RS13395	COG0583	DNA-binding transcription factor activity
B7485_RS13400	COG0385	Bile acid
B7485_RS13405	COG3530	Putative quorum-sensing-regulated virulence factor
B7485_RS13425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7485_RS13430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS13435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7485_RS13440	COG2190	(PTS) system
B7485_RS13460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7485_RS13470	COG4208	sulfate ABC transporter
B7485_RS13475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B7485_RS13480	COG4150	thiosulfate binding
B7485_RS13485	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS13505	COG2837	iron assimilation
B7485_RS13525	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7485_RS13540	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
B7485_RS13545	COG4816	utilization protein
B7485_RS13585	COG0076	glutamate decarboxylase activity
B7485_RS13590	COG0076	glutamate decarboxylase activity
B7485_RS13595	COG0531	amino acid
B7485_RS13600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7485_RS13610	COG4819	ethanolamine utilization protein
B7485_RS13615	COG4917	ethanolamine utilization protein
B7485_RS13620	COG4810	utilization protein
B7485_RS13625	COG0280	phosphate acetyltransferase
B7485_RS13625	COG0281	malic enzyme
B7485_RS13635	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7485_RS13640	COG5342	invasion associated locus B
B7485_RS13650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS13650	COG0493	'glutamate synthase
B7485_RS13660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7485_RS13675	COG1393	Belongs to the ArsC family
B7485_RS13690	COG0400	carboxylic ester hydrolase activity
B7485_RS13700	COG2321	neutral zinc metallopeptidase
B7485_RS13710	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B7485_RS13720	COG2716	regulation of RNA biosynthetic process
B7485_RS13725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B7485_RS13730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS13740	COG0650	Formate hydrogenlyase subunit 4
B7485_RS13745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7485_RS13750	COG4237	Hydrogenase 4 membrane
B7485_RS13755	COG0651	ATP synthesis coupled electron transport
B7485_RS13765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7485_RS13770	COG3260	NADH ubiquinone oxidoreductase 20
B7485_RS13780	COG3604	Transcriptional regulator
B7485_RS13790	COG0628	permease
B7485_RS13795	COG4783	chaperone-mediated protein folding
B7485_RS13800	COG1393	Belongs to the ArsC family
B7485_RS13810	COG2233	PERMEase
B7485_RS13825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B7485_RS13830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B7485_RS13835	COG0248	Ppx GppA phosphatase
B7485_RS13860	COG3133	Outer membrane lipoprotein
B7485_RS13875	COG0517	IMP dehydrogenase activity
B7485_RS13875	COG0516	GMP reductase activity
B7485_RS13885	COG1645	bacterial-type flagellum-dependent swarming motility
B7485_RS13900	COG2976	Protein conserved in bacteria
B7485_RS13935	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS13955	COG2975	iron-sulfur cluster assembly
B7485_RS13960	COG0633	Ferredoxin
B7485_RS13980	COG0822	iron-sulfur transferase activity
B7485_RS14000	COG0483	inositol monophosphate 1-phosphatase activity
B7485_RS14005	COG1073	alpha beta
B7485_RS14010	COG3711	transcriptional antiterminator
B7485_RS14015	COG2814	Major facilitator Superfamily
B7485_RS14020	COG0583	DNA-binding transcription factor activity
B7485_RS14050	COG2259	Doxx family
B7485_RS14055	COG2017	converts alpha-aldose to the beta-anomer
B7485_RS14060	COG1063	alcohol dehydrogenase
B7485_RS14065	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7485_RS14070	COG1129	ABC transporter
B7485_RS14075	COG1879	ABC-type sugar transport system periplasmic component
B7485_RS14080	COG0457	Tetratricopeptide repeat
B7485_RS14085	COG1940	carbohydrate kinase activity
B7485_RS14100	COG0347	Belongs to the P(II) protein family
B7485_RS14105	COG2204	response regulator
B7485_RS14110	COG3170	Tfp pilus assembly protein FimV
B7485_RS14115	COG2205	protein histidine kinase activity
B7485_RS14135	COG0560	Phosphoserine phosphatase
B7485_RS14140	COG1737	Transcriptional regulator
B7485_RS14175	COG5301	cellulose 1,4-beta-cellobiosidase activity
B7485_RS14220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS14255	COG0681	Belongs to the peptidase S26 family
B7485_RS14265	COG3086	response to oxidative stress
B7485_RS14270	COG3026	antisigma factor binding
B7485_RS14275	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
B7485_RS14280	COG1595	DNA-templated transcription, initiation
B7485_RS14300	COG0513	Belongs to the DEAD box helicase family
B7485_RS14305	COG0583	DNA-binding transcription factor activity
B7485_RS14325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7485_RS14330	COG3118	belongs to the thioredoxin family
B7485_RS14335	COG3148	PFAM DTW domain containing protein
B7485_RS14340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7485_RS14340	COG1042	CoA-binding domain protein
B7485_RS14340	COG0045	succinate-CoA ligase (ADP-forming) activity
B7485_RS14345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7485_RS14350	COG5544	Lipoprotein
B7485_RS14355	COG0477	Major facilitator Superfamily
B7485_RS14385	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS14390	COG0564	pseudouridine synthase activity
B7485_RS14400	COG0542	response to heat
B7485_RS14410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B7485_RS14420	COG1605	Chorismate mutase
B7485_RS14420	COG0077	Prephenate dehydratase
B7485_RS14425	COG1605	Chorismate mutase
B7485_RS14425	COG0287	Prephenate dehydrogenase
B7485_RS14430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7485_RS14450	COG2885	chlorophyll binding
B7485_RS14475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B7485_RS14480	COG4137	Cytochrome C assembly protein
B7485_RS14485	COG4536	flavin adenine dinucleotide binding
B7485_RS14505	COG0497	DNA recombination
B7485_RS14510	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS14520	COG2867	negative regulation of translational initiation
B7485_RS14535	COG0582	viral genome integration into host DNA
B7485_RS14555	COG0366	Alpha amylase catalytic
B7485_RS14565	COG0579	oxidoreductase
B7485_RS14575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7485_RS14580	COG1113	amino acid transport
B7485_RS14585	COG1802	Transcriptional regulator
B7485_RS14590	COG1652	LysM domain
B7485_RS14595	COG0401	homolog of Blt101
B7485_RS14605	COG0640	Transcriptional regulator
B7485_RS14610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7485_RS14615	COG2916	Histone family protein nucleoid-structuring protein H-NS
B7485_RS14630	COG4575	ribosome binding
B7485_RS14640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7485_RS14650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7485_RS14655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7485_RS14660	COG4175	Glycine betaine
B7485_RS14665	COG4176	ABC-type proline glycine betaine transport system permease component
B7485_RS14670	COG2113	Glycine betaine
B7485_RS14680	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7485_RS14690	COG1846	Transcriptional regulator
B7485_RS14700	COG2814	Major facilitator Superfamily
B7485_RS14715	COG1238	metal cluster binding
B7485_RS14720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS14750	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B7485_RS14770	COG1546	Belongs to the CinA family
B7485_RS14775	COG2951	lytic endotransglycosylase activity
B7485_RS14785	COG3732	PTS system glucitol sorbitol-specific
B7485_RS14795	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS14805	COG1349	DNA-binding transcription factor activity
B7485_RS14830	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B7485_RS14835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS14840	COG1609	Transcriptional regulator
B7485_RS14845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7485_RS14850	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
B7485_RS14850	COG3261	NADH dehydrogenase
B7485_RS14855	COG0650	Formate hydrogenlyase subunit 4
B7485_RS14860	COG0651	ATP synthesis coupled electron transport
B7485_RS14865	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS14880	COG0375	protein maturation
B7485_RS14885	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B7485_RS14890	COG0298	carbon dioxide binding
B7485_RS14895	COG0409	Hydrogenase expression formation protein
B7485_RS14900	COG0309	Hydrogenase expression formation protein (HypE)
B7485_RS14905	COG3604	Transcriptional regulator
B7485_RS14935	COG1349	DNA-binding transcription factor activity
B7485_RS14940	COG2084	Dehydrogenase
B7485_RS14960	COG3423	Transcriptional regulator
B7485_RS14990	COG1388	LysM domain
B7485_RS14990	COG4942	peptidase
B7485_RS15045	COG2234	aminopeptidase activity
B7485_RS15080	COG0720	synthase
B7485_RS15085	COG0644	oxidoreductase
B7485_RS15090	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B7485_RS15110	COG0477	Major facilitator Superfamily
B7485_RS15115	COG0277	FAD linked oxidase domain protein
B7485_RS15125	COG0602	queuosine metabolic process
B7485_RS15160	COG3956	TIGRFAM MazG family protein
B7485_RS15165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7485_RS15180	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS15185	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS15190	COG2271	Major facilitator Superfamily
B7485_RS15195	COG0716	FMN binding
B7485_RS15200	COG0564	pseudouridine synthase activity
B7485_RS15205	COG3098	single-species biofilm formation
B7485_RS15220	COG1611	Belongs to the LOG family
B7485_RS15225	COG3385	transposase activity
B7485_RS15230	COG0814	amino acid
B7485_RS15235	COG1760	l-serine dehydratase
B7485_RS15245	COG1454	alcohol dehydrogenase
B7485_RS15250	COG0235	Class ii aldolase
B7485_RS15255	COG0738	Major facilitator superfamily
B7485_RS15275	COG1349	DNA-binding transcription factor activity
B7485_RS15285	COG2363	Small membrane protein
B7485_RS15290	COG0583	DNA-binding transcription factor activity
B7485_RS15300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7485_RS15305	COG2166	iron-sulfur cluster assembly
B7485_RS15310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B7485_RS15315	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B7485_RS15330	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7485_RS15340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7485_RS15345	COG1074	ATP-dependent DNA helicase activity
B7485_RS15355	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B7485_RS15360	COG4967	type IV pilus modification protein PilV
B7485_RS15370	COG4795	General secretion pathway protein
B7485_RS15390	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
B7485_RS15410	COG0861	Integral membrane protein TerC family
B7485_RS15420	COG0667	Aldo Keto reductase
B7485_RS15435	COG1609	Transcriptional regulator
B7485_RS15445	COG0583	DNA-binding transcription factor activity
B7485_RS15450	COG1794	racemase activity, acting on amino acids and derivatives
B7485_RS15455	COG2814	Major facilitator Superfamily
B7485_RS15460	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS15470	COG0183	Belongs to the thiolase family
B7485_RS15475	COG0814	amino acid
B7485_RS15480	COG2771	luxR family
B7485_RS15515	COG4974	Belongs to the 'phage' integrase family
B7485_RS15525	COG4942	peptidase
B7485_RS15530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7485_RS15535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B7485_RS15540	COG2080	2 iron, 2 sulfur cluster binding
B7485_RS15565	COG2233	PERMEase
B7485_RS15595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B7485_RS15600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7485_RS15610	COG0716	FMN binding
B7485_RS15630	COG1272	protein, Hemolysin III
B7485_RS15640	COG2723	6-phospho-beta-galactosidase activity
B7485_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS15670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7485_RS15675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7485_RS15680	COG0006	proline dipeptidase activity
B7485_RS15700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B7485_RS15715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7485_RS15730	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7485_RS15730	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7485_RS15735	COG1703	isobutyryl-CoA mutase activity
B7485_RS15740	COG1024	Enoyl-CoA hydratase
B7485_RS15745	COG0427	acetyl-CoA hydrolase
B7485_RS15750	COG0583	DNA-binding transcription factor activity
B7485_RS15755	COG2968	Membrane
B7485_RS15765	COG0668	transmembrane transport
B7485_RS15770	COG0191	fructose-bisphosphate aldolase activity
B7485_RS15805	COG1122	ATPase activity
B7485_RS15810	COG1122	ATPase activity
B7485_RS15815	COG1072	(Pantothenic acid kinase))
B7485_RS15825	COG1494	fructose-1,6-bisphosphatase
B7485_RS15830	COG1063	alcohol dehydrogenase
B7485_RS15845	COG0330	HflC and HflK could
B7485_RS15850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7485_RS15855	COG0501	Belongs to the peptidase M48B family
B7485_RS15900	COG2814	Major facilitator Superfamily
B7485_RS15910	COG2356	endonuclease I
B7485_RS15915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7485_RS15935	COG2805	Type II/IV secretion system protein
B7485_RS15940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B7485_RS15945	COG0762	integral membrane protein
B7485_RS15960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7485_RS15970	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B7485_RS15990	COG0252	asparaginase activity
B7485_RS16000	COG3171	Protein conserved in bacteria
B7485_RS16010	COG1194	a g-specific adenine glycosylase
B7485_RS16025	COG2211	Major facilitator Superfamily
B7485_RS16030	COG1982	Orn Lys Arg decarboxylase major
B7485_RS16035	COG1811	Na channel or pump
B7485_RS16075	COG1620	l-lactate permease
B7485_RS16085	COG3193	protein, possibly involved in utilization of glycolate and propanediol
B7485_RS16095	COG0277	FAD linked oxidase domain protein
B7485_RS16105	COG2186	Transcriptional regulator
B7485_RS16125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B7485_RS16130	COG0306	phosphate transporter
B7485_RS16135	COG0754	glutathionylspermidine amidase activity
B7485_RS16140	COG0625	glutathione transferase activity
B7485_RS16145	COG0298	carbon dioxide binding
B7485_RS16155	COG1773	rubredoxin
B7485_RS16160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B7485_RS16165	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B7485_RS16170	COG5557	Pfam Polysulphide reductase, NrfD
B7485_RS16175	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS16180	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
B7485_RS16195	COG0667	Aldo Keto reductase
B7485_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS16210	COG0848	biopolymer transport protein
B7485_RS16215	COG0811	peptide transport
B7485_RS16220	COG0626	cystathionine gamma-synthase activity
B7485_RS16225	COG0586	Pfam SNARE associated Golgi protein
B7485_RS16230	COG2207	Transcriptional regulator
B7485_RS16235	COG1979	alcohol dehydrogenase
B7485_RS16240	COG0656	L-ascorbic acid biosynthetic process
B7485_RS16250	COG4238	major outer membrane lipoprotein
B7485_RS16260	COG2132	Multicopper oxidase
B7485_RS16265	COG0204	Acyl-transferase
B7485_RS16270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7485_RS16275	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B7485_RS16280	COG3111	PFAM Bacterial OB fold (BOF) protein
B7485_RS16285	COG0745	RESPONSE REGULATOR receiver
B7485_RS16290	COG0642	Histidine kinase
B7485_RS16310	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7485_RS16315	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B7485_RS16320	COG0187	DNA topoisomerase II activity
B7485_RS16325	COG3150	esterase
B7485_RS16330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7485_RS16335	COG3151	Protein conserved in bacteria
B7485_RS16340	COG0494	nUDIX hydrolase
B7485_RS16345	COG1538	Outer membrane efflux protein
B7485_RS16355	COG0754	glutathionylspermidine amidase activity
B7485_RS16360	COG3384	dioxygenase
B7485_RS16375	COG2960	long-chain fatty acid transporting porin activity
B7485_RS16425	COG3025	triphosphatase activity
B7485_RS16430	COG4991	sh3 domain protein
B7485_RS16445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B7485_RS16465	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS16480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B7485_RS16485	COG0358	DNA primase activity
B7485_RS16490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7485_RS16515	COG1695	Transcriptional regulator
B7485_RS16535	COG1609	Transcriptional regulator
B7485_RS16540	COG3250	beta-galactosidase activity
B7485_RS16545	COG2731	YhcH YjgK YiaL family protein
B7485_RS16550	COG0531	amino acid
B7485_RS16560	COG3408	Glycogen debranching enzyme
B7485_RS16560	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
B7485_RS16565	COG1902	pentaerythritol trinitrate reductase activity
B7485_RS16565	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7485_RS16570	COG5499	transcription regulator containing HTH domain
B7485_RS16575	COG4680	protein conserved in bacteria
B7485_RS16585	COG1451	nucleotide metabolic process
B7485_RS16590	COG2949	membrane
B7485_RS16595	COG0673	inositol 2-dehydrogenase activity
B7485_RS16600	COG0861	Integral membrane protein TerC family
B7485_RS16615	COG2721	sulfolactate sulfo-lyase activity
B7485_RS16625	COG2271	Major facilitator Superfamily
B7485_RS16655	COG2186	Transcriptional regulator
B7485_RS16660	COG0586	Pfam SNARE associated Golgi protein
B7485_RS16675	COG4575	ribosome binding
B7485_RS16680	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
B7485_RS16690	COG2259	Doxx family
B7485_RS16695	COG0435	Glutathione S-transferase
B7485_RS16700	COG3152	Membrane
B7485_RS16705	COG0583	DNA-binding transcription factor activity
B7485_RS16710	COG1741	Belongs to the pirin family
B7485_RS16725	COG0814	amino acid
B7485_RS16730	COG1760	l-serine dehydratase
B7485_RS16735	COG0251	oxidation-reduction process
B7485_RS16740	COG1882	Formate acetyltransferase
B7485_RS16745	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7485_RS16755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7485_RS16760	COG0583	DNA-binding transcription factor activity
B7485_RS16790	COG1929	Belongs to the glycerate kinase type-1 family
B7485_RS16795	COG2084	Dehydrogenase
B7485_RS16805	COG2271	Major facilitator Superfamily
B7485_RS16810	COG2721	sulfolactate sulfo-lyase activity
B7485_RS16815	COG1349	DNA-binding transcription factor activity
B7485_RS16825	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS16835	COG3716	PTS system mannose fructose sorbose family IID component
B7485_RS16840	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS16860	COG3715	PTS system
B7485_RS16865	COG3716	PTS system mannose fructose sorbose family IID component
B7485_RS16870	COG0363	glucosamine-6-phosphate deaminase activity
B7485_RS16885	COG3539	Fimbrial protein
B7485_RS16890	COG3121	Chaperone
B7485_RS16910	COG3539	Fimbrial protein
B7485_RS16915	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B7485_RS16935	COG2823	Periplasmic or secreted lipoprotein
B7485_RS16940	COG0701	Predicted permease
B7485_RS16945	COG0702	epimerase
B7485_RS16950	COG0693	protein deglycase activity
B7485_RS16965	COG3153	acetyltransferase
B7485_RS16970	COG3154	lipid carrier protein
B7485_RS16975	COG0826	peptidase U32
B7485_RS16980	COG0826	peptidase U32
B7485_RS16985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7485_RS16990	COG0814	amino acid
B7485_RS16995	COG0513	Belongs to the DEAD box helicase family
B7485_RS17035	COG0195	Participates in both transcription termination and antitermination
B7485_RS17065	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7485_RS17075	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7485_RS17080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7485_RS17090	COG1534	Rna-binding protein
B7485_RS17095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7485_RS17100	COG2027	D-alanyl-D-alanine carboxypeptidase
B7485_RS17110	COG0697	spore germination
B7485_RS17125	COG0142	geranyltranstransferase activity
B7485_RS17130	COG3423	Transcriptional regulator
B7485_RS17140	COG5007	Belongs to the BolA IbaG family
B7485_RS17145	COG3113	response to antibiotic
B7485_RS17150	COG2854	intermembrane phospholipid transfer
B7485_RS17155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7485_RS17160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7485_RS17165	COG1127	ABC transporter
B7485_RS17170	COG0530	calcium, potassium:sodium antiporter activity
B7485_RS17180	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B7485_RS17185	COG3117	lipopolysaccharide transmembrane transporter activity
B7485_RS17190	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B7485_RS17195	COG1137	ATPase activity
B7485_RS17200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B7485_RS17205	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B7485_RS17220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS17225	COG0515	serine threonine protein kinase
B7485_RS17235	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
B7485_RS17240	COG0784	Response regulator, receiver
B7485_RS17240	COG5002	protein histidine kinase activity
B7485_RS17240	COG2198	Histidine kinase
B7485_RS17245	COG1242	4 iron, 4 sulfur cluster binding
B7485_RS17250	COG0070	glutamate synthase
B7485_RS17250	COG0067	glutamate synthase
B7485_RS17250	COG0069	glutamate synthase activity
B7485_RS17255	COG0493	'glutamate synthase
B7485_RS17260	COG4804	nuclease activity
B7485_RS17275	COG2731	YhcH YjgK YiaL family protein
B7485_RS17310	COG3069	C4-dicarboxylate transmembrane transporter activity
B7485_RS17315	COG2969	positive regulation of protein catabolic process
B7485_RS17320	COG0625	glutathione transferase activity
B7485_RS17335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B7485_RS17340	COG3105	Protein conserved in bacteria
B7485_RS17350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7485_RS17370	COG2732	(Barnase) inhibitor
B7485_RS17390	COG0583	DNA-binding transcription factor activity
B7485_RS17395	COG0312	modulator of DNA gyrase
B7485_RS17400	COG3164	Protein of unknown function
B7485_RS17405	COG1530	ribonuclease E activity
B7485_RS17415	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B7485_RS17420	COG1792	Involved in formation and maintenance of cell shape
B7485_RS17425	COG1077	Cell shape determining protein MreB Mrl
B7485_RS17435	COG2199	diguanylate cyclase activity
B7485_RS17435	COG2200	EAL domain
B7485_RS17440	COG0604	alcohol dehydrogenase
B7485_RS17445	COG0511	ligase activity, forming carbon-carbon bonds
B7485_RS17450	COG0439	Biotin carboxylase
B7485_RS17455	COG3924	membrane
B7485_RS17460	COG4145	pantothenate transmembrane transporter activity
B7485_RS17480	COG2189	Belongs to the N(4) N(6)-methyltransferase family
B7485_RS17495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS17510	COG4597	amino acid ABC transporter
B7485_RS17515	COG0765	amino acid transport
B7485_RS17520	COG1126	abc transporter atp-binding protein
B7485_RS17560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B7485_RS17580	COG0551	DNA topoisomerase type I activity
B7485_RS17590	COG0758	DNA mediated transformation
B7485_RS17610	COG0569	domain protein
B7485_RS17620	COG3436	PFAM IS66 Orf2 family protein
B7485_RS17625	COG4372	Transposase
B7485_RS17670	COG0201	protein transport
B7485_RS17760	COG0089	rRNA binding
B7485_RS17830	COG2964	Protein conserved in bacteria
B7485_RS17835	COG0545	Peptidyl-prolyl cis-trans isomerase
B7485_RS17845	COG1047	Peptidyl-prolyl cis-trans
B7485_RS17850	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
B7485_RS17865	COG0488	(ABC) transporter
B7485_RS17870	COG0429	hydrolase of the alpha beta-hydrolase fold
B7485_RS17880	COG3954	Phosphoribulokinase
B7485_RS17885	COG1765	OsmC-like protein
B7485_RS17890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7485_RS17895	COG1289	transmembrane transporter activity
B7485_RS17905	COG0512	Glutamine amidotransferase of anthranilate synthase
B7485_RS17910	COG2184	nucleotidyltransferase activity
B7485_RS17920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7485_RS17935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7485_RS17940	COG2146	nitrite reductase [NAD(P)H] activity
B7485_RS17945	COG2116	formate transmembrane transporter activity
B7485_RS17965	COG2222	sugar isomerase
B7485_RS17970	COG1082	Xylose isomerase domain protein TIM barrel
B7485_RS17985	COG0626	cystathionine gamma-synthase activity
B7485_RS18000	COG1735	metal-dependent hydrolase with the TIM-barrel fold
B7485_RS18005	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B7485_RS18010	COG3457	Alanine racemase
B7485_RS18020	COG2188	Transcriptional regulator
B7485_RS18035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7485_RS18040	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B7485_RS18045	COG3266	domain, Protein
B7485_RS18060	COG4796	Type ii and iii secretion system protein
B7485_RS18075	COG3166	PFAM Fimbrial assembly family protein
B7485_RS18080	COG4972	Pilus assembly protein
B7485_RS18085	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B7485_RS18090	COG0494	nUDIX hydrolase
B7485_RS18100	COG1011	Hydrolase
B7485_RS18105	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B7485_RS18115	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B7485_RS18135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7485_RS18140	COG2183	response to ionizing radiation
B7485_RS18145	COG1918	ferrous iron import across plasma membrane
B7485_RS18160	COG5464	transposase or invertase
B7485_RS18195	COG2610	gluconate transmembrane transporter activity
B7485_RS18200	COG1640	4-alpha-glucanotransferase
B7485_RS18205	COG0058	SHG alpha-glucan phosphorylase activity
B7485_RS18220	COG1690	Belongs to the RtcB family
B7485_RS18225	COG4650	regulator
B7485_RS18230	COG1349	DNA-binding transcription factor activity
B7485_RS18245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7485_RS18255	COG3385	transposase activity
B7485_RS18260	COG0058	SHG alpha-glucan phosphorylase activity
B7485_RS18285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B7485_RS18290	COG2095	MarC family integral membrane protein
B7485_RS18295	COG2610	gluconate transmembrane transporter activity
B7485_RS18300	COG3265	gluconokinase activity
B7485_RS18305	COG1609	Transcriptional regulator
B7485_RS18310	COG1741	Belongs to the pirin family
B7485_RS18315	COG0673	inositol 2-dehydrogenase activity
B7485_RS18320	COG1247	-acetyltransferase
B7485_RS18325	COG0405	Gamma-glutamyltransferase
B7485_RS18335	COG0584	glycerophosphoryl diester phosphodiesterase
B7485_RS18360	COG0410	ABC transporter
B7485_RS18365	COG0411	ABC transporter
B7485_RS18370	COG4177	L-phenylalanine transmembrane transporter activity
B7485_RS18375	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7485_RS18380	COG0683	leucine binding
B7485_RS18385	COG0456	acetyltransferase
B7485_RS18390	COG0683	leucine binding
B7485_RS18395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7485_RS18400	COG2177	Part of the ABC transporter FtsEX involved in
B7485_RS18405	COG2884	Cell division ATP-binding protein ftsE
B7485_RS18410	COG0552	protein localization to endoplasmic reticulum
B7485_RS18415	COG0742	ribosomal rna small subunit methyltransferase
B7485_RS18420	COG3776	membrane
B7485_RS18430	COG3714	YhhN family
B7485_RS18445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B7485_RS18460	COG0628	permease
B7485_RS18465	COG2091	lysine biosynthetic process via aminoadipic acid
B7485_RS18470	COG0747	negative chemotaxis
B7485_RS18475	COG0601	transmembrane transport
B7485_RS18480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7485_RS18510	COG0842	Transport permease protein
B7485_RS18515	COG0842	Transport permease protein
B7485_RS18515	COG1129	ABC transporter
B7485_RS18520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS18605	COG2081	HI0933 family
B7485_RS18610	COG0306	phosphate transporter
B7485_RS18620	COG0589	response to stress
B7485_RS18640	COG0339	signal peptide processing
B7485_RS18645	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B7485_RS18650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7485_RS18660	COG0640	Transcriptional regulator
B7485_RS18665	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7485_RS18670	COG1393	Belongs to the ArsC family
B7485_RS18695	COG3065	identical protein binding
B7485_RS18720	COG3247	response to pH
B7485_RS18725	COG2771	luxR family
B7485_RS18735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS18755	COG1278	Cold shock
B7485_RS18775	COG2885	chlorophyll binding
B7485_RS18780	COG0243	molybdopterin cofactor binding
B7485_RS18785	COG0456	acetyltransferase
B7485_RS18790	COG2818	Glycosylase
B7485_RS18795	COG5571	outer membrane autotransporter
B7485_RS18800	COG2223	nitrite transmembrane transporter activity
B7485_RS18805	COG2194	sulfuric ester hydrolase activity
B7485_RS18815	COG0747	negative chemotaxis
B7485_RS18820	COG0601	transmembrane transport
B7485_RS18825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7485_RS18830	COG0444	Belongs to the ABC transporter superfamily
B7485_RS18835	COG4608	Belongs to the ABC transporter superfamily
B7485_RS18840	COG0814	amino acid
B7485_RS18880	COG2194	sulfuric ester hydrolase activity
B7485_RS18905	COG1215	transferase activity, transferring glycosyl groups
B7485_RS18915	COG1215	transferase activity, transferring glycosyl groups
B7485_RS18920	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B7485_RS18940	COG2200	EAL domain
B7485_RS18940	COG2199	diguanylate cyclase activity
B7485_RS18950	COG0612	Peptidase, M16
B7485_RS18960	COG2200	EAL domain
B7485_RS18965	COG2982	Protein involved in outer membrane biogenesis
B7485_RS18970	COG0477	Major facilitator Superfamily
B7485_RS18975	COG1295	ribonuclease BN
B7485_RS18980	COG0583	DNA-binding transcription factor activity
B7485_RS18985	COG2197	response regulator
B7485_RS18990	COG3385	transposase activity
B7485_RS19010	COG1858	cytochrome C peroxidase
B7485_RS19025	COG2207	Transcriptional regulator
B7485_RS19060	COG3274	enterobacterial common antigen metabolic process
B7485_RS19065	COG4682	membrane
B7485_RS19070	COG4682	membrane
B7485_RS19075	COG1070	Carbohydrate kinase
B7485_RS19095	COG4214	carbohydrate transport
B7485_RS19105	COG2992	FlgJ-related protein
B7485_RS19110	COG0366	Alpha amylase catalytic
B7485_RS19115	COG3977	Valine--pyruvate aminotransferase
B7485_RS19120	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS19125	COG1414	Transcriptional regulator
B7485_RS19150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B7485_RS19155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B7485_RS19160	COG1070	Carbohydrate kinase
B7485_RS19165	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B7485_RS19170	COG3623	hexulose-6-phosphate isomerase
B7485_RS19175	COG0235	Class ii aldolase
B7485_RS19185	COG2211	Major facilitator Superfamily
B7485_RS19195	COG3713	MltA-interacting MipA family protein
B7485_RS19215	COG1566	PFAM secretion protein HlyD family protein
B7485_RS19230	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS19235	COG1454	alcohol dehydrogenase
B7485_RS19240	COG3276	selenocysteine insertion sequence binding
B7485_RS19250	COG0625	glutathione transferase activity
B7485_RS19255	COG1566	PFAM secretion protein HlyD family protein
B7485_RS19265	COG2213	PTS system mannitol-specific
B7485_RS19265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS19275	COG3722	fumarate hydratase activity
B7485_RS19305	COG1620	l-lactate permease
B7485_RS19310	COG2186	Transcriptional regulator
B7485_RS19320	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B7485_RS19325	COG1045	serine acetyltransferase
B7485_RS19340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7485_RS19345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7485_RS19360	COG4942	peptidase
B7485_RS19365	COG2861	carbohydrate metabolic process
B7485_RS19385	COG0156	8-amino-7-oxononanoate synthase activity
B7485_RS19400	COG0859	PFAM glycosyl transferase family 9
B7485_RS19405	COG0859	PFAM glycosyl transferase family 9
B7485_RS19425	COG3642	lipopolysaccharide core region biosynthetic process
B7485_RS19435	COG0515	serine threonine protein kinase
B7485_RS19440	COG0438	transferase activity, transferring glycosyl groups
B7485_RS19445	COG0859	PFAM glycosyl transferase family 9
B7485_RS19455	COG1519	Transferase
B7485_RS19485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7485_RS19510	COG1561	YicC-like family, N-terminal region
B7485_RS19520	COG3645	SOS response
B7485_RS19525	COG2860	membrane
B7485_RS19535	COG0194	GDP metabolic process
B7485_RS19545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7485_RS19550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7485_RS19555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7485_RS19560	COG0786	glutamate:sodium symporter activity
B7485_RS19565	COG2233	PERMEase
B7485_RS19570	COG2982	Protein involved in outer membrane biogenesis
B7485_RS19575	COG1501	Belongs to the glycosyl hydrolase 31 family
B7485_RS19590	COG0582	viral genome integration into host DNA
B7485_RS19745	COG2252	PERMEase
B7485_RS19755	COG2271	Major facilitator Superfamily
B7485_RS19760	COG2271	Major facilitator Superfamily
B7485_RS19765	COG3851	Histidine kinase
B7485_RS19770	COG2197	response regulator
B7485_RS19775	COG0440	acetolactate synthase activity
B7485_RS19780	COG0028	Belongs to the TPP enzyme family
B7485_RS19795	COG2814	Major facilitator Superfamily
B7485_RS19800	COG0641	radical SAM
B7485_RS19810	COG2149	membrane
B7485_RS19825	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7485_RS19830	COG2207	Transcriptional regulator
B7485_RS19845	COG2188	Transcriptional regulator
B7485_RS19865	COG5645	(Lipo)protein
B7485_RS19870	COG0823	Involved in the tonB-independent uptake of proteins
B7485_RS19880	COG2271	Major facilitator Superfamily
B7485_RS19890	COG0800	Aldolase
B7485_RS19895	COG3734	2-keto-3-deoxy-galactonokinase
B7485_RS19900	COG2186	Transcriptional regulator
B7485_RS19910	COG0561	phosphatase activity
B7485_RS19915	COG3753	Protein conserved in bacteria
B7485_RS19920	COG0187	DNA topoisomerase II activity
B7485_RS19930	COG0592	DNA-directed DNA polymerase activity
B7485_RS19985	COG0814	amino acid
B7485_RS20010	COG2091	lysine biosynthetic process via aminoadipic acid
B7485_RS20015	COG0431	NADPH-dependent FMN reductase
B7485_RS20020	COG2252	PERMEase
B7485_RS20025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS20040	COG3436	PFAM IS66 Orf2 family protein
B7485_RS20045	COG4372	Transposase
B7485_RS20050	COG3196	Protein conserved in bacteria
B7485_RS20055	COG0363	glucosamine-6-phosphate deaminase activity
B7485_RS20070	COG2723	6-phospho-beta-galactosidase activity
B7485_RS20075	COG2190	(PTS) system
B7485_RS20075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS20075	COG1263	PTS System
B7485_RS20080	COG3711	transcriptional antiterminator
B7485_RS20085	COG0704	Plays a role in the regulation of phosphate uptake
B7485_RS20090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7485_RS20095	COG0581	inorganic phosphate transmembrane transporter activity
B7485_RS20100	COG0573	inorganic phosphate transmembrane transporter activity
B7485_RS20105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7485_RS20145	COG3385	transposase activity
B7485_RS20200	COG3312	ion transport
B7485_RS20215	COG0716	FMN binding
B7485_RS20220	COG1522	sequence-specific DNA binding
B7485_RS20240	COG3385	transposase activity
B7485_RS20255	COG1129	ABC transporter
B7485_RS20270	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7485_RS20280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS20285	COG1609	Transcriptional regulator
B7485_RS20290	COG0477	Major facilitator Superfamily
B7485_RS20295	COG2186	Transcriptional regulator
B7485_RS20335	COG3085	chromosome segregation
B7485_RS20340	COG0606	chelatase, subunit chli
B7485_RS20360	COG3978	acetolactate synthase activity
B7485_RS20365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7485_RS20375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7485_RS20380	COG0583	DNA-binding transcription factor activity
B7485_RS20390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7485_RS20395	COG0210	DNA helicase
B7485_RS20410	COG3118	belongs to the thioredoxin family
B7485_RS20420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B7485_RS20425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7485_RS20430	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
B7485_RS20435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B7485_RS20440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B7485_RS20445	COG1088	dTDP-glucose 4,6-dehydratase activity
B7485_RS20450	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B7485_RS20455	COG0456	acetyltransferase
B7485_RS20460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7485_RS20465	COG2244	polysaccharide biosynthetic process
B7485_RS20485	COG1113	amino acid transport
B7485_RS20510	COG0641	radical SAM
B7485_RS20520	COG3071	HemY protein
B7485_RS20525	COG2959	enzyme of heme biosynthesis
B7485_RS20530	COG1587	Uroporphyrinogen-III synthase
B7485_RS20540	COG3072	Adenylate cyclase
B7485_RS20575	COG5567	small periplasmic lipoprotein
B7485_RS20585	COG3159	Protein conserved in bacteria
B7485_RS20595	COG1011	Hydrolase
B7485_RS20600	COG0210	DNA helicase
B7485_RS20605	COG3698	Phosphodiester glycosidase
B7485_RS20610	COG3385	transposase activity
B7485_RS20615	COG3698	Phosphodiester glycosidase
B7485_RS20620	COG0598	Magnesium transport protein CorA
B7485_RS20635	COG2962	Rard protein
B7485_RS20640	COG2050	protein possibly involved in aromatic compounds catabolism
B7485_RS20645	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
B7485_RS20650	COG0514	ATP-dependent DNA helicase (RecQ)
B7485_RS20655	COG1280	lysine exporter protein (LysE YggA)
B7485_RS20660	COG1280	lysine exporter protein (LysE YggA)
B7485_RS20665	COG2267	carboxylic ester hydrolase activity
B7485_RS20670	COG0561	phosphatase activity
B7485_RS20675	COG0697	spore germination
B7485_RS20680	COG0583	DNA-binding transcription factor activity
B7485_RS20690	COG0412	Dienelactone hydrolase
B7485_RS20695	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
B7485_RS20700	COG1322	Protein conserved in bacteria
B7485_RS20710	COG3165	ubiquinone biosynthetic process from chorismate
B7485_RS20720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7485_RS20725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7485_RS20730	COG0805	protein transport
B7485_RS20740	COG0250	Participates in transcription elongation, termination and antitermination
B7485_RS20750	COG0543	2 iron, 2 sulfur cluster binding
B7485_RS20770	COG1739	Uncharacterized protein family UPF0029
B7485_RS20775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7485_RS20780	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
B7485_RS20810	COG1763	Mo-molybdopterin cofactor biosynthetic process
B7485_RS20815	COG0746	molybdenum cofactor guanylyltransferase activity
B7485_RS20820	COG3084	Protein conserved in bacteria
B7485_RS20835	COG5339	Protein conserved in bacteria
B7485_RS20840	COG0204	Acyl-transferase
B7485_RS20850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7485_RS20850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7485_RS20865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7485_RS20875	COG2204	response regulator
B7485_RS20880	COG3852	Histidine kinase
B7485_RS20890	COG0174	glutamine synthetase
B7485_RS20895	COG1217	gtp-binding protein TYPA
B7485_RS20900	COG2188	Transcriptional regulator
B7485_RS20905	COG1082	Xylose isomerase domain protein TIM barrel
B7485_RS20910	COG2271	Major facilitator Superfamily
B7485_RS20925	COG2211	Major facilitator Superfamily
B7485_RS20935	COG1501	Belongs to the glycosyl hydrolase 31 family
B7485_RS20940	COG2017	converts alpha-aldose to the beta-anomer
B7485_RS20945	COG2942	2-epimerase
B7485_RS20960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS20965	COG1349	DNA-binding transcription factor activity
B7485_RS20970	COG1011	Hydrolase
B7485_RS20985	COG0456	acetyltransferase
B7485_RS21010	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7485_RS21015	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7485_RS21025	COG2864	formate dehydrogenase
B7485_RS21030	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS21050	COG3711	transcriptional antiterminator
B7485_RS21050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS21055	COG1363	Peptidase, m42
B7485_RS21060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS21105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7485_RS21120	COG2258	MOSC domain
B7485_RS21125	COG2205	protein histidine kinase activity
B7485_RS21130	COG0745	RESPONSE REGULATOR receiver
B7485_RS21135	COG3678	ATP-independent chaperone mediated protein folding
B7485_RS21150	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B7485_RS21175	COG3691	Protein conserved in bacteria
B7485_RS21180	COG0589	response to stress
B7485_RS21190	COG1494	fructose-1,6-bisphosphatase
B7485_RS21215	COG1575	Belongs to the MenA family. Type 1 subfamily
B7485_RS21230	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B7485_RS21235	COG1609	Transcriptional regulator
B7485_RS21240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7485_RS21250	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
B7485_RS21260	COG0626	cystathionine gamma-synthase activity
B7485_RS21265	COG0460	homoserine dehydrogenase
B7485_RS21265	COG0527	aspartate kinase activity
B7485_RS21270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B7485_RS21280	COG0697	spore germination
B7485_RS21285	COG3738	Protein conserved in bacteria
B7485_RS21305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21315	COG1882	Formate acetyltransferase
B7485_RS21320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B7485_RS21325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21330	COG2207	Transcriptional regulator
B7485_RS21335	COG2194	sulfuric ester hydrolase activity
B7485_RS21365	COG3385	transposase activity
B7485_RS21370	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS21390	COG0583	DNA-binding transcription factor activity
B7485_RS21400	COG1309	transcriptional regulator
B7485_RS21415	COG4206	TonB-dependent receptor
B7485_RS21420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7485_RS21450	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B7485_RS21450	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B7485_RS21485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7485_RS21490	COG0250	Participates in transcription elongation, termination and antitermination
B7485_RS21525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B7485_RS21535	COG2104	thiamine diphosphate biosynthetic process
B7485_RS21540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7485_RS21575	COG3068	Protein conserved in bacteria
B7485_RS21590	COG3678	ATP-independent chaperone mediated protein folding
B7485_RS21595	COG4191	Histidine kinase
B7485_RS21600	COG2204	response regulator
B7485_RS21605	COG0151	Belongs to the GarS family
B7485_RS21635	COG0456	acetyltransferase
B7485_RS21650	COG2224	Isocitrate lyase
B7485_RS21665	COG1414	Transcriptional regulator
B7485_RS21670	COG0646	methionine synthase
B7485_RS21670	COG1410	methionine synthase
B7485_RS21675	COG1283	sodium-dependent phosphate transmembrane transporter activity
B7485_RS21735	COG3592	Divergent 4Fe-4S mono-cluster
B7485_RS21750	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B7485_RS21755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS21755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS21760	COG3647	Membrane
B7485_RS21765	COG2211	Major facilitator Superfamily
B7485_RS21770	COG1486	melibiose metabolic process
B7485_RS21775	COG2169	Transcriptional regulator
B7485_RS21780	COG1982	Orn Lys Arg decarboxylase major
B7485_RS21785	COG2207	Transcriptional regulator
B7485_RS21790	COG0531	amino acid
B7485_RS21795	COG2194	sulfuric ester hydrolase activity
B7485_RS21800	COG0745	RESPONSE REGULATOR receiver
B7485_RS21805	COG0642	Histidine kinase
B7485_RS21815	COG0477	Major facilitator Superfamily
B7485_RS21825	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B7485_RS21830	COG2824	Alkylphosphonate utilization operon protein PhnA
B7485_RS21835	COG2764	glyoxalase bleomycin resistance protein dioxygenase
B7485_RS21845	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B7485_RS21850	COG3639	organic phosphonate transmembrane transporter activity
B7485_RS21870	COG2207	Transcriptional regulator
B7485_RS21875	COG0789	Transcriptional regulator
B7485_RS21880	COG2252	PERMEase
B7485_RS21885	COG0025	NhaP-type Na H and K H
B7485_RS21890	COG1357	PFAM Pentapeptide repeats (8 copies)
B7485_RS21900	COG3162	membrane
B7485_RS21905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7485_RS21915	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
B7485_RS21920	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS21925	COG3301	Polysulphide reductase, NrfD
B7485_RS21930	COG1138	Cytochrome C-type biogenesis protein
B7485_RS21935	COG3088	subunit of a heme lyase
B7485_RS21940	COG4235	cytochrome complex assembly
B7485_RS21945	COG1301	dicarboxylic acid transport
B7485_RS21950	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B7485_RS21980	COG0629	single-stranded DNA binding
B7485_RS21985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7485_RS21990	COG2315	Protein conserved in bacteria
B7485_RS21995	COG0432	Pfam Uncharacterised protein family UPF0047
B7485_RS22000	COG3700	Belongs to the class B bacterial acid phosphatase family
B7485_RS22010	COG1448	Aminotransferase
B7485_RS22015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7485_RS22020	COG0305	Participates in initiation and elongation during chromosome replication
B7485_RS22025	COG0604	alcohol dehydrogenase
B7485_RS22035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7485_RS22055	COG0735	belongs to the Fur family
B7485_RS22060	COG3237	CsbD-like
B7485_RS22065	COG0534	Mate efflux family protein
B7485_RS22075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B7485_RS22115	COG2182	Extracellular solute-binding protein
B7485_RS22120	COG1175	transmembrane transport
B7485_RS22125	COG3833	ABC-type maltose transport systems, permease component
B7485_RS22130	COG0477	Major facilitator Superfamily
B7485_RS22130	COG2814	Major facilitator Superfamily
B7485_RS22145	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS22175	COG0527	aspartate kinase activity
B7485_RS22180	COG4372	Transposase
B7485_RS22185	COG3436	PFAM IS66 Orf2 family protein
B7485_RS22205	COG3366	ferrous iron transmembrane transporter activity
B7485_RS22210	COG0700	Nucleoside recognition
B7485_RS22215	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B7485_RS22220	COG0583	DNA-binding transcription factor activity
B7485_RS22245	COG2186	Transcriptional regulator
B7485_RS22250	COG0246	Mannitol dehydrogenase
B7485_RS22260	COG2610	gluconate transmembrane transporter activity
B7485_RS22265	COG3539	Fimbrial protein
B7485_RS22270	COG3539	Fimbrial protein
B7485_RS22275	COG3539	Fimbrial protein
B7485_RS22280	COG3188	usher protein
B7485_RS22285	COG3121	Chaperone
B7485_RS22290	COG3539	Fimbrial protein
B7485_RS22300	COG4974	Belongs to the 'phage' integrase family
B7485_RS22310	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B7485_RS22330	COG1349	DNA-binding transcription factor activity
B7485_RS22335	COG0440	acetolactate synthase activity
B7485_RS22375	COG0582	viral genome integration into host DNA
B7485_RS22385	COG1064	alcohol dehydrogenase
B7485_RS22390	COG0433	COG0433 Predicted ATPase
B7485_RS22395	COG0795	lipopolysaccharide-transporting ATPase activity
B7485_RS22400	COG0795	lipopolysaccharide-transporting ATPase activity
B7485_RS22410	COG2927	DNA polymerase III (CHI subunit)
B7485_RS22420	COG4269	membrane
B7485_RS22425	COG0456	acetyltransferase
B7485_RS22430	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
B7485_RS22450	COG2731	YhcH YjgK YiaL family protein
B7485_RS22455	COG1309	transcriptional regulator
B7485_RS22460	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS22465	COG0251	oxidation-reduction process
B7485_RS22485	COG0251	oxidation-reduction process
B7485_RS22490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7485_RS22500	COG1609	Transcriptional regulator
B7485_RS22505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS22505	COG1263	PTS System
B7485_RS22510	COG0366	Alpha amylase catalytic
B7485_RS22515	COG1328	CTP reductase activity
B7485_RS22520	COG0602	queuosine metabolic process
B7485_RS22525	COG3783	Cytochrome b(562)
B7485_RS22530	COG0312	modulator of DNA gyrase
B7485_RS22540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7485_RS22560	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7485_RS22565	COG1129	ABC transporter
B7485_RS22575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B7485_RS22580	COG2105	PFAM AIG2 family protein
B7485_RS22585	COG2911	Protein conserved in bacteria
B7485_RS22590	COG0729	surface antigen
B7485_RS22600	COG1253	flavin adenine dinucleotide binding
B7485_RS22610	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
B7485_RS22625	COG0737	Belongs to the 5'-nucleotidase family
B7485_RS22630	COG1733	regulation of RNA biosynthetic process
B7485_RS22635	COG0702	epimerase
B7485_RS22640	COG0697	spore germination
B7485_RS22650	COG1113	amino acid transport
B7485_RS22655	COG0545	Peptidyl-prolyl cis-trans isomerase
B7485_RS22665	COG3061	Opacity-associated protein A
B7485_RS22670	COG1309	transcriptional regulator
B7485_RS22710	COG1309	transcriptional regulator
B7485_RS22725	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B7485_RS22730	COG1027	Aspartate ammonia-lyase
B7485_RS22735	COG3030	protein affecting phage T7 exclusion by the F plasmid
B7485_RS22740	COG0531	amino acid
B7485_RS22775	COG1509	lysine 2,3-aminomutase activity
B7485_RS22785	COG5510	response to toxic substance
B7485_RS22790	COG5510	response to toxic substance
B7485_RS22795	COG2076	Multidrug Resistance protein
B7485_RS22800	COG3040	lipid binding
B7485_RS22805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7485_RS22820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7485_RS22825	COG1053	succinate dehydrogenase
B7485_RS22835	COG0531	amino acid
B7485_RS22850	COG3264	Mechanosensitive ion channel
B7485_RS22850	COG1511	domain protein
B7485_RS22895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B7485_RS22900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B7485_RS22900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B7485_RS22905	COG0802	atpase or kinase
B7485_RS22910	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7485_RS22930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7485_RS22935	COG0330	HflC and HflK could
B7485_RS22940	COG0330	HflC and HflK could
B7485_RS22945	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
B7485_RS22960	COG0557	exoribonuclease II activity
B7485_RS22965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7485_RS22975	COG3766	membrane
B7485_RS22980	COG5463	Belongs to the UPF0441 family
B7485_RS22985	COG0754	glutathionylspermidine amidase activity
B7485_RS22990	COG1960	acyl-CoA dehydrogenase activity
B7485_RS23000	COG3650	response to hydrogen peroxide
B7485_RS23005	COG1073	alpha beta
B7485_RS23065	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B7485_RS23105	COG0732	type I restriction modification DNA specificity domain
B7485_RS23130	COG0523	cobalamin synthesis protein
B7485_RS23135	COG2879	small protein
B7485_RS23140	COG1966	Carbon starvation protein
B7485_RS23145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7485_RS23175	COG3971	2-oxopent-4-enoate hydratase activity
B7485_RS23185	COG3384	dioxygenase
B7485_RS23190	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS23195	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7485_RS23200	COG1846	Transcriptional regulator
B7485_RS23205	COG0840	transmembrane signaling receptor activity
B7485_RS23215	COG1802	Transcriptional regulator
B7485_RS23235	COG1484	DNA-dependent DNA replication
B7485_RS23250	COG2966	Psort location CytoplasmicMembrane, score
B7485_RS23265	COG2197	response regulator
B7485_RS23270	COG4114	ferric iron reductase
B7485_RS23300	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
B7485_RS23305	COG0456	acetyltransferase
B7485_RS23310	COG1011	Hydrolase
B7485_RS23320	COG2823	Periplasmic or secreted lipoprotein
B7485_RS23330	COG4667	esterase of the alpha-beta hydrolase superfamily
B7485_RS23335	COG0084	hydrolase, TatD family'
B7485_RS23340	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B7485_RS23345	COG1328	CTP reductase activity
B7485_RS23380	COG3726	membrane protein affecting hemolysin expression
B7485_RS23385	COG0560	Phosphoserine phosphatase
B7485_RS23390	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B7485_RS23395	COG1056	cytidyltransferase-related domain
B7485_RS23395	COG3172	ATPase kinase involved in NAD metabolism
B7485_RS23400	COG0488	(ABC) transporter
B7485_RS23405	COG0741	lytic transglycosylase activity
B7485_RS23425	COG2207	Transcriptional regulator
B7485_RS23425	COG3708	Transcriptional regulator
B7485_RS23430	COG3045	CreA protein
B7485_RS23435	COG0745	RESPONSE REGULATOR receiver
B7485_RS23440	COG2205	protein histidine kinase activity
B7485_RS23445	COG4452	Inner membrane protein CreD
B7485_RS23450	COG0745	RESPONSE REGULATOR receiver
B7485_RS23460	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA