locus-tag	class	description
B7485_RS00010	COG0527	aspartate kinase activity
B7485_RS00010	COG0460	homoserine dehydrogenase
B7485_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7485_RS00040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7485_RS00045	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7485_RS00050	COG1584	GPR1 FUN34 yaaH family protein
B7485_RS00055	COG4735	regulation of single-species biofilm formation
B7485_RS00085	COG0583	DNA-binding transcription factor activity
B7485_RS00110	COG0196	riboflavin kinase activity
B7485_RS00125	COG1047	Peptidyl-prolyl cis-trans
B7485_RS00145	COG0505	Belongs to the CarA family
B7485_RS00150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7485_RS00210	COG2271	Major facilitator Superfamily
B7485_RS00225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7485_RS00250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7485_RS00260	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B7485_RS00265	COG0564	pseudouridine synthase activity
B7485_RS00275	COG0417	DNA replication proofreading
B7485_RS00280	COG0235	Class ii aldolase
B7485_RS00295	COG4977	sequence-specific DNA binding
B7485_RS00300	COG0586	Pfam SNARE associated Golgi protein
B7485_RS00310	COG1178	ABC-type Fe3 transport system permease component
B7485_RS00315	COG4143	(ABC) transporter
B7485_RS00330	COG2814	Major facilitator Superfamily
B7485_RS00360	COG0583	DNA-binding transcription factor activity
B7485_RS00365	COG0028	Belongs to the TPP enzyme family
B7485_RS00370	COG0440	acetolactate synthase activity
B7485_RS00380	COG1609	Transcriptional regulator
B7485_RS00400	COG3116	cell division
B7485_RS00405	COG0768	penicillin binding
B7485_RS00415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B7485_RS00430	COG0772	Belongs to the SEDS family
B7485_RS00450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B7485_RS00455	COG0849	cell division
B7485_RS00460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B7485_RS00480	COG0494	nUDIX hydrolase
B7485_RS00505	COG1459	type II secretion system
B7485_RS00515	COG4969	Belongs to the N-Me-Phe pilin family
B7485_RS00520	COG0157	Belongs to the NadC ModD family
B7485_RS00525	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7485_RS00530	COG3725	Membrane protein required for beta-lactamase induction
B7485_RS00540	COG2186	Transcriptional regulator
B7485_RS00545	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B7485_RS00550	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7485_RS00555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7485_RS00565	COG1049	propionate catabolic process, 2-methylcitrate cycle
B7485_RS00590	COG2132	Multicopper oxidase
B7485_RS00595	COG4993	Dehydrogenase
B7485_RS00600	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B7485_RS00605	COG0288	reversible hydration of carbon dioxide
B7485_RS00610	COG1131	(ABC) transporter
B7485_RS00615	COG0842	Transport permease protein
B7485_RS00620	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS00625	COG0726	polysaccharide deacetylase
B7485_RS00635	COG5464	transposase or invertase
B7485_RS00660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B7485_RS00665	COG0617	tRNA 3'-terminal CCA addition
B7485_RS00675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7485_RS00685	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B7485_RS00690	COG1643	Atp-dependent helicase
B7485_RS00695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7485_RS00700	COG4774	siderophore transport
B7485_RS00705	COG1120	ATPase activity
B7485_RS00710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7485_RS00715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7485_RS00740	COG2860	membrane
B7485_RS00760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7485_RS00785	COG0024	Methionine aminopeptidase
B7485_RS00815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7485_RS00820	COG0575	Belongs to the CDS family
B7485_RS00825	COG0750	zinc metalloprotease
B7485_RS00835	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B7485_RS00840	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7485_RS00865	COG0587	DNA-directed DNA polymerase activity
B7485_RS00875	COG1982	Orn Lys Arg decarboxylase major
B7485_RS00880	COG0346	lactoylglutathione lyase activity
B7485_RS00890	COG4568	rho-dependent transcription termination
B7485_RS00900	COG4681	YaeQ
B7485_RS00905	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B7485_RS00910	COG3015	lipoprotein NlpE involved in copper resistance
B7485_RS00915	COG0791	NLP P60 protein
B7485_RS00925	COG1720	tRNA m6t6A37 methyltransferase activity
B7485_RS00935	COG1464	Belongs to the NlpA lipoprotein family
B7485_RS00940	COG2011	ABC-type metal ion transport system permease component
B7485_RS00945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7485_RS00950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B7485_RS00985	COG0656	L-ascorbic acid biosynthetic process
B7485_RS00990	COG3385	transposase activity
B7485_RS00995	COG0583	DNA-binding transcription factor activity
B7485_RS01005	COG2226	methyltransferase
B7485_RS01010	COG1388	LysM domain
B7485_RS01010	COG0741	lytic transglycosylase activity
B7485_RS01020	COG2226	methyltransferase
B7485_RS01030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7485_RS01165	COG1785	Belongs to the alkaline phosphatase family
B7485_RS01175	COG1181	Belongs to the D-alanine--D-alanine ligase family
B7485_RS01195	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
B7485_RS01200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7485_RS01205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7485_RS01250	COG0113	porphobilinogen synthase activity
B7485_RS01255	COG2175	clavaminate synthase activity
B7485_RS01260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7485_RS01270	COG4521	taurine ABC transporter
B7485_RS01290	COG1556	Lactate utilization protein
B7485_RS01295	COG1139	Iron-sulfur cluster binding protein
B7485_RS01300	COG0247	lactate metabolic process
B7485_RS01360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7485_RS01370	COG1960	acyl-CoA dehydrogenase activity
B7485_RS01380	COG0121	glutamine amidotransferase
B7485_RS01385	COG3034	peptidoglycan biosynthetic process
B7485_RS01390	COG0791	NLP P60 protein
B7485_RS01395	COG1943	Transposase
B7485_RS01415	COG2161	toxin-antitoxin pair type II binding
B7485_RS01425	COG0454	-acetyltransferase
B7485_RS01430	COG1690	Belongs to the RtcB family
B7485_RS01440	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7485_RS01460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B7485_RS01525	COG2246	polysaccharide biosynthetic process
B7485_RS01595	COG3706	GGDEF domain
B7485_RS01600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7485_RS01620	COG4126	flavin adenine dinucleotide binding
B7485_RS01645	COG1940	carbohydrate kinase activity
B7485_RS01650	COG2814	Major facilitator Superfamily
B7485_RS01655	COG0419	ATPase involved in DNA repair
B7485_RS01660	COG0420	3'-5' exonuclease activity
B7485_RS01665	COG0745	RESPONSE REGULATOR receiver
B7485_RS01670	COG5002	protein histidine kinase activity
B7485_RS01675	COG1114	Component of the transport system for branched-chain amino acids
B7485_RS01680	COG1113	amino acid transport
B7485_RS01685	COG0366	Alpha amylase catalytic
B7485_RS01705	COG1862	Preprotein translocase
B7485_RS01710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7485_RS01715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7485_RS01720	COG1403	HNH endonuclease
B7485_RS01725	COG3248	Nucleoside-binding outer membrane protein
B7485_RS01730	COG4238	major outer membrane lipoprotein
B7485_RS01740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7485_RS01740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7485_RS01755	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B7485_RS01760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B7485_RS01765	COG0667	Aldo Keto reductase
B7485_RS01775	COG0142	geranyltranstransferase activity
B7485_RS01790	COG0693	protein deglycase activity
B7485_RS01795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B7485_RS01840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7485_RS01845	COG1845	cytochrome c oxidase, subunit III
B7485_RS01870	COG3436	PFAM IS66 Orf2 family protein
B7485_RS01880	COG2223	nitrite transmembrane transporter activity
B7485_RS01885	COG3056	Lipoprotein
B7485_RS01890	COG0271	Belongs to the BolA IbaG family
B7485_RS01910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B7485_RS01915	COG0776	regulation of translation
B7485_RS01920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7485_RS01925	COG1555	photosystem II stabilization
B7485_RS01930	COG0824	Thioesterase
B7485_RS01940	COG4533	DNA binding
B7485_RS01950	COG1522	sequence-specific DNA binding
B7485_RS01955	COG1132	(ABC) transporter
B7485_RS01960	COG1132	(ABC) transporter
B7485_RS01965	COG0347	Belongs to the P(II) protein family
B7485_RS01970	COG0004	ammonium transporteR
B7485_RS01975	COG1946	Acyl-CoA thioesterase
B7485_RS01980	COG3126	Type III secretion system lipoprotein chaperone (YscW)
B7485_RS01985	COG3385	transposase activity
B7485_RS01990	COG3695	enzyme binding
B7485_RS02000	COG5507	3-demethylubiquinone-9 3-methyltransferase
B7485_RS02005	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B7485_RS02015	COG0110	maltose O-acetyltransferase activity
B7485_RS02030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7485_RS02035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS02040	COG1309	transcriptional regulator
B7485_RS02045	COG1196	nuclear chromosome segregation
B7485_RS02045	COG3264	Mechanosensitive ion channel
B7485_RS02055	COG3923	Primosomal replication protein n
B7485_RS02060	COG2832	Protein of unknown function (DUF454)
B7485_RS02070	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7485_RS02110	COG4651	solute:proton antiporter activity
B7485_RS02110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7485_RS02115	COG2223	nitrite transmembrane transporter activity
B7485_RS02120	COG0737	Belongs to the 5'-nucleotidase family
B7485_RS02125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7485_RS02130	COG3735	TraB family
B7485_RS02140	COG3093	addiction module antidote protein HigA
B7485_RS02145	COG2217	Heavy metal translocating P-type atpase
B7485_RS02155	COG0531	amino acid
B7485_RS02160	COG0789	Transcriptional regulator
B7485_RS02165	COG1585	Membrane protein implicated in regulation of membrane protease activity
B7485_RS02170	COG0330	HflC and HflK could
B7485_RS02175	COG4619	ABC transporter
B7485_RS02180	COG0390	transport system, permease component
B7485_RS02185	COG3118	belongs to the thioredoxin family
B7485_RS02190	COG0300	oxidoreductase activity
B7485_RS02200	COG4181	ATPase activity
B7485_RS02205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B7485_RS02210	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B7485_RS02220	COG0583	DNA-binding transcription factor activity
B7485_RS02230	COG1414	Transcriptional regulator
B7485_RS02235	COG3960	tartronate-semialdehyde synthase activity
B7485_RS02250	COG3257	ureidoglycine aminohydrolase activity
B7485_RS02255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7485_RS02265	COG0549	Belongs to the carbamate kinase family
B7485_RS02270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B7485_RS02275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B7485_RS02285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7485_RS02295	COG1988	membrane-bound metal-dependent
B7485_RS02300	COG2501	S4 domain
B7485_RS02310	COG3539	Fimbrial protein
B7485_RS02315	COG3121	Chaperone
B7485_RS02340	COG2207	Transcriptional regulator
B7485_RS02350	COG4783	chaperone-mediated protein folding
B7485_RS02355	COG4783	chaperone-mediated protein folding
B7485_RS02360	COG4783	chaperone-mediated protein folding
B7485_RS02365	COG1215	transferase activity, transferring glycosyl groups
B7485_RS02370	COG5002	protein histidine kinase activity
B7485_RS02375	COG0745	RESPONSE REGULATOR receiver
B7485_RS02380	COG1538	Outer membrane efflux protein
B7485_RS02390	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS02430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7485_RS02435	COG1113	amino acid transport
B7485_RS02440	COG0668	transmembrane transport
B7485_RS02445	COG0778	Nitroreductase
B7485_RS02450	COG2315	Protein conserved in bacteria
B7485_RS02500	COG2977	Belongs to the P-Pant transferase superfamily
B7485_RS02505	COG4771	TonB-dependent receptor
B7485_RS02510	COG2382	esterase
B7485_RS02515	COG3251	PFAM MbtH domain protein
B7485_RS02535	COG1120	ATPase activity
B7485_RS02540	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7485_RS02545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7485_RS02555	COG4592	Periplasmic binding protein
B7485_RS02565	COG1021	2,3-dihydroxybenzoate-AMP ligase
B7485_RS02570	COG3433	isochorismatase activity
B7485_RS02570	COG1535	isochorismatase
B7485_RS02575	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS02580	COG2050	protein possibly involved in aromatic compounds catabolism
B7485_RS02585	COG1966	Carbon starvation protein
B7485_RS02590	COG2879	small protein
B7485_RS02595	COG0371	Dehydrogenase
B7485_RS02600	COG0436	Aminotransferase
B7485_RS02640	COG0583	DNA-binding transcription factor activity
B7485_RS02645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7485_RS02650	COG0450	alkyl hydroperoxide reductase
B7485_RS02655	COG3634	alkyl hydroperoxide reductase activity
B7485_RS02665	COG1063	alcohol dehydrogenase
B7485_RS02670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7485_RS02675	COG3719	Belongs to the RNase T2 family
B7485_RS02695	COG3051	citrate lyase alpha subunit
B7485_RS02700	COG2301	Belongs to the HpcH HpaI aldolase family
B7485_RS02710	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
B7485_RS02720	COG0582	viral genome integration into host DNA
B7485_RS02725	COG0561	phosphatase activity
B7485_RS02735	COG4149	molybdate abc transporter
B7485_RS02740	COG0725	ABC transporter, periplasmic molybdate-binding protein
B7485_RS02750	COG3585	molybdate ion transport
B7485_RS02750	COG2005	Transcriptional regulator
B7485_RS02755	COG1119	ATPase activity
B7485_RS02760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7485_RS02765	COG1085	galactose-1-phosphate uridylyltransferase
B7485_RS02775	COG2017	converts alpha-aldose to the beta-anomer
B7485_RS02785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7485_RS02800	COG3201	nicotinamide mononucleotide transporter
B7485_RS02835	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
B7485_RS02840	COG2885	chlorophyll binding
B7485_RS02850	COG3064	Membrane
B7485_RS02855	COG0848	biopolymer transport protein
B7485_RS02860	COG0811	peptide transport
B7485_RS02865	COG0824	Thioesterase
B7485_RS02870	COG3790	cyd operon protein YbgE
B7485_RS02875	COG4890	Cyd operon protein YbgT
B7485_RS02880	COG1294	oxidase, subunit
B7485_RS02885	COG1271	oxidase subunit
B7485_RS02895	COG0383	alpha-mannosidase activity
B7485_RS02900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS02900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS02900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS02905	COG2188	Transcriptional regulator
B7485_RS02910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B7485_RS02920	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7485_RS02925	COG0567	Dehydrogenase, E1 component
B7485_RS02930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7485_RS02935	COG1053	succinate dehydrogenase
B7485_RS02940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B7485_RS02945	COG2009	succinate dehydrogenase
B7485_RS02955	COG0372	Belongs to the citrate synthase family
B7485_RS02960	COG3539	Fimbrial protein
B7485_RS02980	COG3121	Chaperone
B7485_RS02990	COG3180	Ammonia monooxygenase
B7485_RS03010	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B7485_RS03015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7485_RS03025	COG0415	Belongs to the DNA photolyase family
B7485_RS03030	COG3272	Protein of unknown function (DUF1722)
B7485_RS03045	COG3209	COG3209 Rhs family protein
B7485_RS03090	COG0745	RESPONSE REGULATOR receiver
B7485_RS03110	COG0531	amino acid
B7485_RS03115	COG0033	Phosphoglucomutase
B7485_RS03120	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
B7485_RS03125	COG0596	Alpha beta hydrolase
B7485_RS03135	COG0716	FMN binding
B7485_RS03145	COG0735	belongs to the Fur family
B7485_RS03165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS03165	COG1263	PTS System
B7485_RS03165	COG2190	(PTS) system
B7485_RS03175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B7485_RS03180	COG1940	carbohydrate kinase activity
B7485_RS03180	COG1846	Transcriptional regulator
B7485_RS03185	COG0647	UMP catabolic process
B7485_RS03190	COG0367	asparagine synthase
B7485_RS03235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7485_RS03245	COG1702	phosphate starvation-inducible protein PhoH
B7485_RS03255	COG4535	Mg2 and Co2 transporter CorC
B7485_RS03265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS03270	COG0765	amino acid transport
B7485_RS03275	COG0765	amino acid transport
B7485_RS03280	COG1126	abc transporter atp-binding protein
B7485_RS03295	COG2214	Heat shock protein DnaJ domain protein
B7485_RS03305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B7485_RS03310	COG2214	Heat shock protein DnaJ domain protein
B7485_RS03320	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B7485_RS03325	COG2888	peptidyl-tyrosine sulfation
B7485_RS03340	COG1466	dna polymerase III delta subunit
B7485_RS03350	COG0406	alpha-ribazole phosphatase activity
B7485_RS03355	COG0799	negative regulation of ribosome biogenesis
B7485_RS03365	COG0768	penicillin binding
B7485_RS03370	COG0772	Belongs to the SEDS family
B7485_RS03375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B7485_RS03380	COG1686	Belongs to the peptidase S11 family
B7485_RS03395	COG0583	DNA-binding transcription factor activity
B7485_RS03405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7485_RS03410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7485_RS03430	COG3069	C4-dicarboxylate transmembrane transporter activity
B7485_RS03445	COG3423	Transcriptional regulator
B7485_RS03510	COG1783	phage Terminase large subunit
B7485_RS03540	COG0582	viral genome integration into host DNA
B7485_RS03545	COG4677	pectinesterase activity
B7485_RS03550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7485_RS03555	COG0471	metal ion transport
B7485_RS03560	COG2828	Protein conserved in bacteria
B7485_RS03575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B7485_RS03605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7485_RS03620	COG3646	Phage regulatory protein
B7485_RS03645	COG1396	sequence-specific DNA binding
B7485_RS03680	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B7485_RS03830	COG1484	DNA-dependent DNA replication
B7485_RS03835	COG0305	Participates in initiation and elongation during chromosome replication
B7485_RS03885	COG3772	lysozyme
B7485_RS04085	COG1881	PFAM PEBP family protein
B7485_RS04090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7485_RS04105	COG2226	methyltransferase
B7485_RS04110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B7485_RS04120	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B7485_RS04130	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7485_RS04140	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B7485_RS04145	COG0314	molybdopterin synthase activity
B7485_RS04150	COG0670	Belongs to the BI1 family
B7485_RS04155	COG0670	Belongs to the BI1 family
B7485_RS04160	COG0392	lysyltransferase activity
B7485_RS04170	COG3568	Endonuclease Exonuclease Phosphatase
B7485_RS04180	COG0842	Transport permease protein
B7485_RS04185	COG0842	Transport permease protein
B7485_RS04190	COG1131	(ABC) transporter
B7485_RS04200	COG1309	transcriptional regulator
B7485_RS04220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7485_RS04225	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B7485_RS04235	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7485_RS04250	COG3385	transposase activity
B7485_RS04275	COG1126	abc transporter atp-binding protein
B7485_RS04280	COG0765	amino acid transport
B7485_RS04285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS04295	COG5006	permease, DMT superfamily
B7485_RS04305	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B7485_RS04310	COG2194	sulfuric ester hydrolase activity
B7485_RS04320	COG1321	iron dependent repressor
B7485_RS04325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7485_RS04330	COG1376	ErfK ybiS ycfS ynhG family protein
B7485_RS04335	COG0488	(ABC) transporter
B7485_RS04345	COG0561	phosphatase activity
B7485_RS04350	COG1882	Formate acetyltransferase
B7485_RS04355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B7485_RS04360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7485_RS04365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7485_RS04370	COG0303	'Molybdopterin
B7485_RS04375	COG1446	asparaginase
B7485_RS04400	COG2200	EAL domain
B7485_RS04405	COG2199	diguanylate cyclase activity
B7485_RS04420	COG2133	pyrroloquinoline quinone binding
B7485_RS04425	COG2133	pyrroloquinoline quinone binding
B7485_RS04430	COG0625	glutathione transferase activity
B7485_RS04435	COG1686	Belongs to the peptidase S11 family
B7485_RS04450	COG1349	DNA-binding transcription factor activity
B7485_RS04455	COG0671	phosphoesterase, PA-phosphatase related
B7485_RS04460	COG2814	Major facilitator Superfamily
B7485_RS04470	COG0561	phosphatase activity
B7485_RS04475	COG0738	Major facilitator superfamily
B7485_RS04480	COG3226	Transcriptional regulator
B7485_RS04495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7485_RS04505	COG0778	Nitroreductase
B7485_RS04520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B7485_RS04525	COG3842	ATPase activity
B7485_RS04530	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7485_RS04535	COG1177	transmembrane transport
B7485_RS04550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS04555	COG4160	amino acid transport
B7485_RS04560	COG4215	(ABC) transporter
B7485_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS04570	COG1126	abc transporter atp-binding protein
B7485_RS04600	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7485_RS04605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7485_RS04610	COG0702	epimerase
B7485_RS04615	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
B7485_RS04620	COG0028	Belongs to the TPP enzyme family
B7485_RS04625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7485_RS04635	COG2431	L-lysine efflux transmembrane transporter activity
B7485_RS04655	COG3593	DNA synthesis involved in DNA repair
B7485_RS04660	COG2990	Protein conserved in bacteria
B7485_RS04665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS04675	COG1278	Cold shock
B7485_RS04685	COG0542	response to heat
B7485_RS04710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B7485_RS04715	COG4988	ABC transporter
B7485_RS04720	COG0492	ferredoxin-NADP+ reductase activity
B7485_RS04725	COG1522	sequence-specific DNA binding
B7485_RS04740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7485_RS04755	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS04760	COG3302	dmso reductase anchor subunit
B7485_RS04765	COG1335	isochorismatase
B7485_RS04785	COG3436	PFAM IS66 Orf2 family protein
B7485_RS04820	COG0583	DNA-binding transcription factor activity
B7485_RS04835	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7485_RS04845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B7485_RS04850	COG1882	Formate acetyltransferase
B7485_RS04855	COG2116	formate transmembrane transporter activity
B7485_RS04860	COG1944	ATP diphosphatase activity
B7485_RS04880	COG3385	transposase activity
B7485_RS04885	COG0501	Belongs to the peptidase M48B family
B7485_RS04895	COG0539	negative regulation of cytoplasmic translation
B7485_RS04920	COG3214	Protein conserved in bacteria
B7485_RS04935	COG3173	Aminoglycoside phosphotransferase
B7485_RS04940	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B7485_RS04945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B7485_RS04955	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
B7485_RS04965	COG3385	transposase activity
B7485_RS04970	COG2989	Protein conserved in bacteria
B7485_RS04975	COG3108	Peptidase M15
B7485_RS04980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7485_RS04985	COG1448	Aminotransferase
B7485_RS05005	COG0308	aminopeptidase N
B7485_RS05025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7485_RS05035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7485_RS05040	COG0431	NADPH-dependent FMN reductase
B7485_RS05060	COG3188	usher protein
B7485_RS05065	COG3539	Fimbrial protein
B7485_RS05070	COG3539	Fimbrial protein
B7485_RS05075	COG3539	Fimbrial protein
B7485_RS05095	COG3217	Mosc domain protein beta barrel domain protein
B7485_RS05095	COG0633	Ferredoxin
B7485_RS05105	COG0488	(ABC) transporter
B7485_RS05110	COG2995	paraquat-inducible protein a
B7485_RS05115	COG3008	intermembrane lipid transfer
B7485_RS05115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7485_RS05120	COG3009	Protein conserved in bacteria
B7485_RS05125	COG3130	regulation of translation
B7485_RS05135	COG1067	ATP-dependent peptidase activity
B7485_RS05155	COG3070	regulator of competence-specific genes
B7485_RS05165	COG1289	transmembrane transporter activity
B7485_RS05170	COG3304	Inner membrane component domain
B7485_RS05175	COG0210	DNA helicase
B7485_RS05190	COG1832	CoA-binding protein
B7485_RS05205	COG1254	Belongs to the acylphosphatase family
B7485_RS05210	COG2920	part of a sulfur-relay system
B7485_RS05215	COG0670	Belongs to the BI1 family
B7485_RS05225	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
B7485_RS05230	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B7485_RS05235	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
B7485_RS05240	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B7485_RS05245	COG1999	signal sequence binding
B7485_RS05250	COG1773	rubredoxin
B7485_RS05255	COG1271	oxidase subunit
B7485_RS05260	COG1294	oxidase, subunit
B7485_RS05275	COG3206	protein involved in exopolysaccharide biosynthesis
B7485_RS05275	COG0489	protein tyrosine kinase activity
B7485_RS05280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7485_RS05285	COG1596	polysaccharide export
B7485_RS05290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS05310	COG1278	Cold shock
B7485_RS05325	COG1879	ABC-type sugar transport system periplasmic component
B7485_RS05330	COG0745	RESPONSE REGULATOR receiver
B7485_RS05335	COG3005	denitrification pathway
B7485_RS05340	COG0243	molybdopterin cofactor binding
B7485_RS05390	COG3729	General stress protein
B7485_RS05395	COG2233	PERMEase
B7485_RS05435	COG1309	transcriptional regulator
B7485_RS05455	COG2822	iron ion transport
B7485_RS05465	COG1702	phosphate starvation-inducible protein PhoH
B7485_RS05470	COG3658	cytochrome
B7485_RS05500	COG3381	protein complex oligomerization
B7485_RS05525	COG2197	response regulator
B7485_RS05565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7485_RS05580	COG2943	transferase activity, transferring hexosyl groups
B7485_RS05665	COG1560	Kdo2-lipid A biosynthetic process
B7485_RS05680	COG3038	cytochrome b561
B7485_RS05715	COG2999	glutathione oxidoreductase activity
B7485_RS05725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7485_RS05735	COG0673	inositol 2-dehydrogenase activity
B7485_RS05740	COG0728	peptidoglycan biosynthetic process
B7485_RS05745	COG3418	PFAM FlgN family protein
B7485_RS05750	COG2747	anti-sigma28 factor FlgM
B7485_RS05755	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
B7485_RS05760	COG1815	bacterial-type flagellum-dependent cell motility
B7485_RS05770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B7485_RS05775	COG1749	Flagellar hook protein flgE
B7485_RS05785	COG4786	Flagellar basal body rod
B7485_RS05800	COG1705	Flagellar rod assembly protein muramidase FlgJ
B7485_RS05800	COG3951	Flagellar rod assembly protein muramidase FlgJ
B7485_RS05810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7485_RS05815	COG1530	ribonuclease E activity
B7485_RS05820	COG0564	pseudouridine synthase activity
B7485_RS05825	COG0424	maF-like protein
B7485_RS05830	COG1399	metal-binding, possibly nucleic acid-binding protein
B7485_RS05850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B7485_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS05865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7485_RS05870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7485_RS05875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7485_RS05885	COG0470	DNA polymerase III
B7485_RS05890	COG0084	hydrolase, TatD family'
B7485_RS05895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS05895	COG1263	PTS System
B7485_RS05910	COG0537	adenosine 5'-monophosphoramidase activity
B7485_RS05915	COG5633	Lipoprotein
B7485_RS05920	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
B7485_RS05940	COG1252	NADH dehydrogenase
B7485_RS05950	COG1309	transcriptional regulator
B7485_RS05960	COG1388	LysM domain
B7485_RS05960	COG1376	ErfK ybiS ycfS ynhG family protein
B7485_RS05965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B7485_RS05970	COG4763	Acyl-transferase
B7485_RS05975	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7485_RS05985	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7485_RS06000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B7485_RS06005	COG1177	transmembrane transport
B7485_RS06015	COG3842	ATPase activity
B7485_RS06025	COG2850	peptidyl-arginine hydroxylation
B7485_RS06145	COG4626	Terminase
B7485_RS06145	COG1802	Transcriptional regulator
B7485_RS06165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7485_RS06190	COG0538	isocitrate dehydrogenase activity
B7485_RS06200	COG2200	EAL domain
B7485_RS06255	COG2894	cell division
B7485_RS06300	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7485_RS06315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B7485_RS06320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7485_RS06340	COG2719	SpoVR family
B7485_RS06350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7485_RS06365	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7485_RS06375	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B7485_RS06390	COG0157	Belongs to the NadC ModD family
B7485_RS06395	COG0500	methyltransferase
B7485_RS06400	COG1120	ATPase activity
B7485_RS06405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7485_RS06410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7485_RS06435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7485_RS06435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS06435	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
B7485_RS06440	COG1461	Dihydroxyacetone kinase
B7485_RS06445	COG2376	Dihydroxyacetone kinase
B7485_RS06450	COG3284	Transcriptional regulator
B7485_RS06455	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS06460	COG0012	GTP binding
B7485_RS06475	COG0659	secondary active sulfate transmembrane transporter activity
B7485_RS06480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7485_RS06505	COG2890	protein-(glutamine-N5) methyltransferase activity
B7485_RS06510	COG3094	Invasion gene expression up-regulator, SirB
B7485_RS06535	COG0387	Pfam Sodium calcium exchanger
B7485_RS06540	COG4572	Cation transport regulator
B7485_RS06545	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B7485_RS06550	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B7485_RS06555	COG4932	domain protein
B7485_RS06560	COG2197	response regulator
B7485_RS06565	COG3850	Histidine kinase
B7485_RS06570	COG2223	nitrite transmembrane transporter activity
B7485_RS06575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B7485_RS06580	COG1140	nitrate reductase beta subunit
B7485_RS06585	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B7485_RS06590	COG2181	nitrate reductase activity
B7485_RS06605	COG0788	formyltetrahydrofolate deformylase activity
B7485_RS06615	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7485_RS06620	COG0745	RESPONSE REGULATOR receiver
B7485_RS06625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7485_RS06635	COG1435	thymidine kinase activity
B7485_RS06640	COG3385	transposase activity
B7485_RS06645	COG1454	alcohol dehydrogenase
B7485_RS06645	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS06650	COG2095	MarC family integral membrane protein
B7485_RS06655	COG4166	transmembrane transport
B7485_RS06660	COG0601	transmembrane transport
B7485_RS06665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7485_RS06670	COG0444	Belongs to the ABC transporter superfamily
B7485_RS06675	COG4608	Belongs to the ABC transporter superfamily
B7485_RS06695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7485_RS06705	COG2350	Protein conserved in bacteria
B7485_RS06710	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
B7485_RS06715	COG1607	acyl-coa hydrolase
B7485_RS06735	COG3047	cAMP biosynthetic process
B7485_RS06740	COG3685	Protein conserved in bacteria
B7485_RS06745	COG3685	Protein conserved in bacteria
B7485_RS06750	COG3729	General stress protein
B7485_RS06765	COG0134	indole-3-glycerol-phosphate synthase activity
B7485_RS06765	COG0135	phosphoribosylanthranilate isomerase activity
B7485_RS06770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7485_RS06770	COG0512	Glutamine amidotransferase of anthranilate synthase
B7485_RS06775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7485_RS06785	COG0613	PHP domain protein
B7485_RS06790	COG0009	L-threonylcarbamoyladenylate synthase
B7485_RS06800	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
B7485_RS06805	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS06810	COG0616	signal peptide processing
B7485_RS06820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7485_RS06825	COG0583	DNA-binding transcription factor activity
B7485_RS06845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7485_RS06855	COG0671	phosphoesterase, PA-phosphatase related
B7485_RS06860	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
B7485_RS06865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B7485_RS06875	COG0023	Translation Initiation Factor
B7485_RS06885	COG1349	DNA-binding transcription factor activity
B7485_RS06905	COG5001	Diguanylate cyclase
B7485_RS06920	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7485_RS06920	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7485_RS06925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B7485_RS06930	COG2852	Protein conserved in bacteria
B7485_RS06935	COG4172	Belongs to the ABC transporter superfamily
B7485_RS06940	COG4172	Belongs to the ABC transporter superfamily
B7485_RS06945	COG4171	peptide transport system, permease
B7485_RS06950	COG4168	peptide transport system, permease
B7485_RS06955	COG4166	transmembrane transport
B7485_RS06965	COG0531	amino acid
B7485_RS06975	COG0174	glutamine synthetase
B7485_RS06985	COG1917	Cupin 2, conserved barrel domain protein
B7485_RS06985	COG1396	sequence-specific DNA binding
B7485_RS06990	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS06995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7485_RS07000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7485_RS07005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B7485_RS07010	COG1842	Phage shock protein A
B7485_RS07020	COG1983	PspC domain protein
B7485_RS07030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7485_RS07035	COG0366	Alpha amylase catalytic
B7485_RS07055	COG1175	transmembrane transport
B7485_RS07060	COG0395	ABC-type sugar transport system, permease component
B7485_RS07065	COG1063	alcohol dehydrogenase
B7485_RS07080	COG1554	hydrolase, family 65, central catalytic
B7485_RS07085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS07100	COG1609	Transcriptional regulator
B7485_RS07105	COG3106	COG3106 Predicted ATPase
B7485_RS07115	COG3283	Transcriptional regulator of aromatic amino acids metabolism
B7485_RS07120	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B7485_RS07125	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS07130	COG2866	Carboxypeptidase
B7485_RS07135	COG0702	epimerase
B7485_RS07145	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS07155	COG3756	Protein conserved in bacteria
B7485_RS07160	COG1484	DNA-dependent DNA replication
B7485_RS07265	COG4974	Belongs to the 'phage' integrase family
B7485_RS07310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7485_RS07315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7485_RS07320	COG1121	(ABC) transporter
B7485_RS07330	COG0582	viral genome integration into host DNA
B7485_RS07475	COG1956	GAF domain-containing protein
B7485_RS07485	COG0793	Belongs to the peptidase S41A family
B7485_RS07495	COG2814	Major facilitator Superfamily
B7485_RS07500	COG1414	Transcriptional regulator
B7485_RS07530	COG2226	methyltransferase
B7485_RS07550	COG3716	PTS system mannose fructose sorbose family IID component
B7485_RS07555	COG3715	PTS system
B7485_RS07560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS07560	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS07565	COG1253	flavin adenine dinucleotide binding
B7485_RS07570	COG2200	EAL domain
B7485_RS07575	COG1760	l-serine dehydratase
B7485_RS07585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7485_RS07600	COG0251	oxidation-reduction process
B7485_RS07605	COG1199	ATP-dependent helicase activity
B7485_RS07610	COG1214	PFAM Peptidase M22, glycoprotease
B7485_RS07615	COG3065	identical protein binding
B7485_RS07620	COG0318	PFAM AMP-dependent synthetase and ligase
B7485_RS07625	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B7485_RS07630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7485_RS07635	COG4638	Rieske (2fe-2S)
B7485_RS07660	COG3713	MltA-interacting MipA family protein
B7485_RS07665	COG0656	L-ascorbic acid biosynthetic process
B7485_RS07670	COG0676	glucose-6-phosphate 1-epimerase activity
B7485_RS07675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7485_RS07685	COG3139	Protein of unknown function (DUF1315)
B7485_RS07690	COG1063	alcohol dehydrogenase
B7485_RS07695	COG2271	Major facilitator Superfamily
B7485_RS07705	COG0191	fructose-bisphosphate aldolase activity
B7485_RS07710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS07715	COG0667	Aldo Keto reductase
B7485_RS07720	COG1349	DNA-binding transcription factor activity
B7485_RS07725	COG2814	Major facilitator Superfamily
B7485_RS07730	COG1335	isochorismatase
B7485_RS07735	COG0252	asparaginase activity
B7485_RS07740	COG0616	signal peptide processing
B7485_RS07745	COG0778	Nitroreductase
B7485_RS07755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7485_RS07775	COG0494	nUDIX hydrolase
B7485_RS07780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7485_RS07790	COG4136	ATPase activity
B7485_RS07795	COG4135	transport system, permease component
B7485_RS07800	COG4135	transport system, permease component
B7485_RS07805	COG4135	transport system, permease component
B7485_RS07815	COG3385	transposase activity
B7485_RS07825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7485_RS07830	COG0398	Pfam SNARE associated Golgi protein
B7485_RS07845	COG0708	Exodeoxyribonuclease III
B7485_RS07875	COG3678	ATP-independent chaperone mediated protein folding
B7485_RS07895	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS07900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7485_RS07905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7485_RS07910	COG1447	Phosphotransferase system cellobiose-specific component IIA
B7485_RS07920	COG1486	melibiose metabolic process
B7485_RS07930	COG0753	catalase activity
B7485_RS07950	COG1988	membrane-bound metal-dependent
B7485_RS07955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS07965	COG3001	Fructosamine kinase
B7485_RS07975	COG1105	Belongs to the carbohydrate kinase PfkB family
B7485_RS07985	COG3137	Salt-induced outer membrane protein
B7485_RS08055	COG0386	Belongs to the glutathione peroxidase family
B7485_RS08065	COG0791	NLP P60 protein
B7485_RS08070	COG2200	EAL domain
B7485_RS08080	COG4256	Hemin uptake protein
B7485_RS08095	COG0574	Belongs to the PEP-utilizing enzyme family
B7485_RS08095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7485_RS08100	COG0318	PFAM AMP-dependent synthetase and ligase
B7485_RS08105	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B7485_RS08110	COG0644	oxidoreductase
B7485_RS08120	COG2086	electron transfer activity
B7485_RS08125	COG2207	Transcriptional regulator
B7485_RS08125	COG1917	Cupin 2, conserved barrel domain protein
B7485_RS08135	COG3119	arylsulfatase activity
B7485_RS08175	COG3077	Addiction module antitoxin, RelB DinJ family
B7485_RS08180	COG2026	Addiction module toxin, RelE StbE family
B7485_RS08200	COG1403	HNH endonuclease
B7485_RS08205	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B7485_RS08210	COG0484	heat shock protein binding
B7485_RS08260	COG0246	Mannitol dehydrogenase
B7485_RS08270	COG1802	Transcriptional regulator
B7485_RS08280	COG0339	signal peptide processing
B7485_RS08285	COG1546	Belongs to the CinA family
B7485_RS08305	COG2814	Major facilitator Superfamily
B7485_RS08310	COG0697	spore germination
B7485_RS08320	COG4977	sequence-specific DNA binding
B7485_RS08325	COG1846	Transcriptional regulator
B7485_RS08345	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS08360	COG2199	diguanylate cyclase activity
B7485_RS08380	COG3781	membrane
B7485_RS08445	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS08510	COG0243	molybdopterin cofactor binding
B7485_RS08525	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS08530	COG3302	dmso reductase anchor subunit
B7485_RS08535	COG3381	protein complex oligomerization
B7485_RS08545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B7485_RS08550	COG1940	carbohydrate kinase activity
B7485_RS08555	COG0583	DNA-binding transcription factor activity
B7485_RS08575	COG3591	Belongs to the peptidase S1B family
B7485_RS08595	COG0628	permease
B7485_RS08600	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B7485_RS08605	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B7485_RS08615	COG0531	amino acid
B7485_RS08625	COG3136	membrane protein required for alginate biosynthesis
B7485_RS08630	COG0745	RESPONSE REGULATOR receiver
B7485_RS08635	COG1823	symporter activity
B7485_RS08640	COG2205	protein histidine kinase activity
B7485_RS08655	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS08655	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS08665	COG5339	Protein conserved in bacteria
B7485_RS08680	COG3250	beta-galactosidase activity
B7485_RS08685	COG1309	transcriptional regulator
B7485_RS08700	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS08705	COG1609	Transcriptional regulator
B7485_RS08710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS08710	COG1263	PTS System
B7485_RS08715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B7485_RS08725	COG0673	inositol 2-dehydrogenase activity
B7485_RS08765	COG4659	FMN binding
B7485_RS08775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7485_RS08780	COG3104	oligopeptide transport
B7485_RS08785	COG0625	glutathione transferase activity
B7485_RS08825	COG3133	Outer membrane lipoprotein
B7485_RS08840	COG1566	PFAM secretion protein HlyD family protein
B7485_RS08850	COG2032	superoxide dismutase activity
B7485_RS08855	COG4989	oxidoreductase activity
B7485_RS08860	COG3313	Fe-S protein
B7485_RS08865	COG1309	transcriptional regulator
B7485_RS08870	COG1902	pentaerythritol trinitrate reductase activity
B7485_RS08875	COG0346	lactoylglutathione lyase activity
B7485_RS08890	COG0675	Transposase, IS605 OrfB family
B7485_RS08900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B7485_RS08905	COG0791	NLP P60 protein
B7485_RS08910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7485_RS08915	COG2814	Major facilitator Superfamily
B7485_RS08930	COG0583	DNA-binding transcription factor activity
B7485_RS08935	COG2814	Major facilitator Superfamily
B7485_RS08940	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7485_RS08945	COG0307	riboflavin synthase, alpha
B7485_RS08955	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS08975	COG4529	Protein conserved in bacteria
B7485_RS08985	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
B7485_RS08990	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS09005	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS09020	COG0469	pyruvate kinase activity
B7485_RS09025	COG4238	major outer membrane lipoprotein
B7485_RS09030	COG1376	ErfK ybiS ycfS ynhG family protein
B7485_RS09045	COG0719	Fe-S assembly protein
B7485_RS09050	COG0396	ATPase activity
B7485_RS09055	COG0719	Fe-S assembly protein
B7485_RS09060	COG0316	Belongs to the HesB IscA family
B7485_RS09070	COG2050	protein possibly involved in aromatic compounds catabolism
B7485_RS09075	COG0277	FAD linked oxidase domain protein
B7485_RS09075	COG0247	lactate metabolic process
B7485_RS09080	COG0628	permease
B7485_RS09095	COG0738	Major facilitator superfamily
B7485_RS09100	COG2271	Major facilitator Superfamily
B7485_RS09125	COG0641	radical SAM
B7485_RS09140	COG4771	TonB-dependent receptor
B7485_RS09145	COG0612	Peptidase, M16
B7485_RS09155	COG0076	glutamate decarboxylase activity
B7485_RS09160	COG0531	amino acid
B7485_RS09165	COG1649	PFAM Uncharacterised BCR, COG1649
B7485_RS09185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7485_RS09190	COG0444	Belongs to the ABC transporter superfamily
B7485_RS09200	COG1764	response to oxidative stress
B7485_RS09220	COG3093	addiction module antidote protein HigA
B7485_RS09225	COG2864	formate dehydrogenase
B7485_RS09230	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS09240	COG0697	spore germination
B7485_RS09255	COG4886	Leucine-rich repeat (LRR) protein
B7485_RS09275	COG1140	nitrate reductase beta subunit
B7485_RS09300	COG1802	Transcriptional regulator
B7485_RS09305	COG2130	NADP-dependent
B7485_RS09320	COG1247	-acetyltransferase
B7485_RS09325	COG3238	Protein conserved in bacteria
B7485_RS09355	COG1177	transmembrane transport
B7485_RS09395	COG0500	methyltransferase
B7485_RS09400	COG1275	C4-dicarboxylate transporter malic acid transport protein
B7485_RS09405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B7485_RS09410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7485_RS09415	COG2841	Protein conserved in bacteria
B7485_RS09425	COG5383	Protein conserved in bacteria
B7485_RS09430	COG0583	DNA-binding transcription factor activity
B7485_RS09435	COG0840	transmembrane signaling receptor activity
B7485_RS09470	COG3038	cytochrome b561
B7485_RS09475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7485_RS09480	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS09510	COG1643	Atp-dependent helicase
B7485_RS09535	COG2267	carboxylic ester hydrolase activity
B7485_RS09540	COG4589	Belongs to the CDS family
B7485_RS09545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7485_RS09575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7485_RS09580	COG2911	Protein conserved in bacteria
B7485_RS09590	COG3784	Protein of unknown function (DUF1318)
B7485_RS09605	COG3042	response to heat
B7485_RS09610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B7485_RS09610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7485_RS09610	COG1013	pyruvate-flavodoxin oxidoreductase activity
B7485_RS09610	COG0674	pyruvate-flavodoxin oxidoreductase activity
B7485_RS09630	COG0589	response to stress
B7485_RS09640	COG0513	Belongs to the DEAD box helicase family
B7485_RS09655	COG2840	Smr protein MutS2
B7485_RS09695	COG2207	Transcriptional regulator
B7485_RS09705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7485_RS09710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7485_RS09715	COG0589	response to stress
B7485_RS09745	COG0668	transmembrane transport
B7485_RS09750	COG4166	transmembrane transport
B7485_RS09820	COG2372	response to copper ion
B7485_RS09835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7485_RS09840	COG1770	oligopeptidase
B7485_RS09845	COG2979	Protein of unknown function (DUF533)
B7485_RS09865	COG0800	Aldolase
B7485_RS09870	COG0129	dihydroxy-acid dehydratase activity
B7485_RS09875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B7485_RS09880	COG1737	Transcriptional regulator
B7485_RS09885	COG0469	pyruvate kinase activity
B7485_RS09895	COG0739	heme binding
B7485_RS09900	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
B7485_RS09910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7485_RS09940	COG0217	transcriptional regulatory protein
B7485_RS09945	COG0494	nUDIX hydrolase
B7485_RS09955	COG1335	isochorismatase
B7485_RS09960	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS10070	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS10105	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B7485_RS10165	COG1801	Protein of unknown function DUF72
B7485_RS10170	COG3788	relative of glutathione S-transferase, MAPEG superfamily
B7485_RS10185	COG0243	molybdopterin cofactor binding
B7485_RS10190	COG3005	denitrification pathway
B7485_RS10200	COG3102	Protein conserved in bacteria
B7485_RS10210	COG3755	Protein conserved in bacteria
B7485_RS10225	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7485_RS10230	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7485_RS10235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7485_RS10240	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B7485_RS10270	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B7485_RS10275	COG0745	RESPONSE REGULATOR receiver
B7485_RS10285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7485_RS10290	COG0840	transmembrane signaling receptor activity
B7485_RS10295	COG0840	transmembrane signaling receptor activity
B7485_RS10300	COG0835	chemotaxis
B7485_RS10310	COG1360	Flagellar Motor Protein
B7485_RS10315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B7485_RS10335	COG0589	response to stress
B7485_RS10345	COG1877	trehalose-phosphatase activity
B7485_RS10350	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7485_RS10365	COG1528	Iron-storage protein
B7485_RS10385	COG1528	Iron-storage protein
B7485_RS10395	COG0814	amino acid
B7485_RS10400	COG3318	Belongs to the UPF0149 family
B7485_RS10400	COG3012	SEC-C Motif Domain Protein
B7485_RS10430	COG2197	response regulator
B7485_RS10450	COG1126	abc transporter atp-binding protein
B7485_RS10455	COG0765	amino acid transport
B7485_RS10465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS10475	COG1191	sigma factor activity
B7485_RS10485	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B7485_RS10490	COG1516	flagellar protein fliS
B7485_RS10500	COG0366	Alpha amylase catalytic
B7485_RS10510	COG2391	methyltransferase activity
B7485_RS10515	COG0425	Belongs to the sulfur carrier protein TusA family
B7485_RS10550	COG1881	PFAM PEBP family protein
B7485_RS10555	COG2076	Multidrug Resistance protein
B7485_RS10580	COG1317	bacterial-type flagellum organization
B7485_RS10585	COG1157	protein secretion by the type III secretion system
B7485_RS10595	COG3144	bacterial-type flagellum assembly
B7485_RS10600	COG1580	Controls the rotational direction of flagella during chemotaxis
B7485_RS10605	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7485_RS10610	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7485_RS10615	COG3190	flagellar
B7485_RS10620	COG1338	Plays a role in the flagellum-specific transport system
B7485_RS10625	COG1987	bacterial-type flagellum assembly
B7485_RS10630	COG1684	flagellar biosynthetic protein fliR
B7485_RS10635	COG2197	response regulator
B7485_RS10665	COG5475	Uncharacterized small protein (DUF2158)
B7485_RS10670	COG2354	Protein conserved in bacteria
B7485_RS10675	COG0697	spore germination
B7485_RS10680	COG3727	T/G mismatch-specific endonuclease activity
B7485_RS10685	COG0270	DNA (cytosine-5-)-methyltransferase activity
B7485_RS10730	COG0745	RESPONSE REGULATOR receiver
B7485_RS10735	COG2351	hydroxyisourate hydrolase activity
B7485_RS10750	COG3443	Belongs to the bacterial solute-binding protein 9 family
B7485_RS10765	COG0500	methyltransferase
B7485_RS10835	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B7485_RS10840	COG1403	HNH endonuclease
B7485_RS10910	COG0477	Major facilitator Superfamily
B7485_RS11065	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B7485_RS11070	COG1403	HNH endonuclease
B7485_RS11140	COG0477	Major facilitator Superfamily
B7485_RS11175	COG4372	Transposase
B7485_RS11200	COG0582	viral genome integration into host DNA
B7485_RS11205	COG2925	Exonuclease
B7485_RS11210	COG0425	Belongs to the sulfur carrier protein TusA family
B7485_RS11215	COG2391	methyltransferase activity
B7485_RS11220	COG0531	amino acid
B7485_RS11230	COG0583	DNA-binding transcription factor activity
B7485_RS11235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7485_RS11240	COG4115	mRNA cleavage
B7485_RS11395	COG0438	transferase activity, transferring glycosyl groups
B7485_RS11400	COG2327	Polysaccharide pyruvyl transferase
B7485_RS11405	COG2244	polysaccharide biosynthetic process
B7485_RS11410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7485_RS11415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7485_RS11420	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
B7485_RS11420	COG0662	Cupin 2, conserved barrel domain protein
B7485_RS11425	COG0297	glycogen (starch) synthase activity
B7485_RS11430	COG1051	belongs to the nudix hydrolase family
B7485_RS11440	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B7485_RS11445	COG0110	maltose O-acetyltransferase activity
B7485_RS11465	COG0438	transferase activity, transferring glycosyl groups
B7485_RS11470	COG1045	serine acetyltransferase
B7485_RS11475	COG0463	Glycosyl transferase, family 2
B7485_RS11480	COG3206	protein involved in exopolysaccharide biosynthesis
B7485_RS11480	COG0489	protein tyrosine kinase activity
B7485_RS11485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7485_RS11490	COG1596	polysaccharide export
B7485_RS11500	COG2982	Protein involved in outer membrane biogenesis
B7485_RS11510	COG0572	uridine kinase
B7485_RS11520	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS11525	COG4245	von Willebrand factor, type A
B7485_RS11530	COG0631	protein serine/threonine phosphatase activity
B7485_RS11535	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
B7485_RS11540	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
B7485_RS11550	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B7485_RS11560	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS11585	COG2205	protein histidine kinase activity
B7485_RS11590	COG0745	RESPONSE REGULATOR receiver
B7485_RS11600	COG0826	peptidase U32
B7485_RS11625	COG1063	alcohol dehydrogenase
B7485_RS11630	COG3775	system Galactitol-specific IIC component
B7485_RS11635	COG3414	Phosphotransferase system galactitol-specific IIB component
B7485_RS11640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS11655	COG1830	Aldolase
B7485_RS11660	COG2211	Major facilitator Superfamily
B7485_RS11670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS11675	COG2188	Transcriptional regulator
B7485_RS11680	COG3757	hydrolase, family 25
B7485_RS11685	COG0351	phosphomethylpyrimidine kinase
B7485_RS11705	COG5455	response to cobalt ion
B7485_RS11715	COG3188	usher protein
B7485_RS11720	COG3121	Chaperone
B7485_RS11725	COG3539	Fimbrial protein
B7485_RS11735	COG0489	protein tyrosine kinase activity
B7485_RS11780	COG0714	Associated with various cellular activities
B7485_RS11785	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B7485_RS11790	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B7485_RS11795	COG4715	Zinc finger, swim domain protein
B7485_RS11805	COG4808	Protein conserved in bacteria
B7485_RS11810	COG4807	Protein conserved in bacteria
B7485_RS11820	COG3275	phosphorelay sensor kinase activity
B7485_RS11825	COG3385	transposase activity
B7485_RS11845	COG0500	methyltransferase
B7485_RS11865	COG5301	cellulose 1,4-beta-cellobiosidase activity
B7485_RS11890	COG0789	Transcriptional regulator
B7485_RS11910	COG1174	glycine betaine transport
B7485_RS11915	COG1125	glycine betaine transport
B7485_RS11920	COG1174	glycine betaine transport
B7485_RS11925	COG1732	Glycine betaine
B7485_RS11930	COG1472	Belongs to the glycosyl hydrolase 3 family
B7485_RS11935	COG0277	FAD linked oxidase domain protein
B7485_RS11940	COG1686	Belongs to the peptidase S11 family
B7485_RS11950	COG0586	Pfam SNARE associated Golgi protein
B7485_RS11980	COG1346	cytolysis
B7485_RS11990	COG2949	membrane
B7485_RS12000	COG0493	'glutamate synthase
B7485_RS12010	COG4211	Belongs to the binding-protein-dependent transport system permease family
B7485_RS12015	COG1129	ABC transporter
B7485_RS12020	COG1879	ABC-type sugar transport system periplasmic component
B7485_RS12025	COG1609	Transcriptional regulator
B7485_RS12030	COG2311	Membrane
B7485_RS12045	COG4771	TonB-dependent receptor
B7485_RS12050	COG0833	amino acid
B7485_RS12055	COG0583	DNA-binding transcription factor activity
B7485_RS12060	COG2855	membrane
B7485_RS12070	COG1522	sequence-specific DNA binding
B7485_RS12070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS12075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7485_RS12090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7485_RS12095	COG2313	pseudouridylate synthase activity
B7485_RS12100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS12105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS12105	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B7485_RS12105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS12110	COG1105	Belongs to the carbohydrate kinase PfkB family
B7485_RS12115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS12115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS12120	COG2814	Major facilitator Superfamily
B7485_RS12140	COG0246	Mannitol dehydrogenase
B7485_RS12145	COG0523	cobalamin synthesis protein
B7485_RS12150	COG0671	phosphoesterase, PA-phosphatase related
B7485_RS12155	COG0791	NLP P60 protein
B7485_RS12160	COG2200	EAL domain
B7485_RS12165	COG4166	transmembrane transport
B7485_RS12170	COG4174	ABC transporter (Permease)
B7485_RS12175	COG4239	(ABC) transporter, permease
B7485_RS12180	COG4172	Belongs to the ABC transporter superfamily
B7485_RS12190	COG2814	Major facilitator Superfamily
B7485_RS12195	COG1187	pseudouridine synthase activity
B7485_RS12200	COG1061	Type III restriction enzyme res subunit
B7485_RS12220	COG3083	sulfuric ester hydrolase activity
B7485_RS12230	COG0582	viral genome integration into host DNA
B7485_RS12280	COG2963	transposase activity
B7485_RS12285	COG2826	transposase and inactivated derivatives, IS30 family
B7485_RS12305	COG3344	reverse transcriptase
B7485_RS12330	COG2246	polysaccharide biosynthetic process
B7485_RS12335	COG0463	Glycosyl transferase, family 2
B7485_RS12370	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS12375	COG2197	response regulator
B7485_RS12380	COG4235	cytochrome complex assembly
B7485_RS12380	COG3088	subunit of a heme lyase
B7485_RS12385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7485_RS12390	COG1138	Cytochrome C-type biogenesis protein
B7485_RS12400	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7485_RS12405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7485_RS12410	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7485_RS12420	COG3005	denitrification pathway
B7485_RS12425	COG3043	anaerobic respiration
B7485_RS12430	COG0348	domain, Protein
B7485_RS12435	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS12445	COG3062	negative regulation of establishment of protein localization
B7485_RS12450	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS12450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS12470	COG4615	Cyclic peptide transporter
B7485_RS12475	COG3145	DNA-N1-methyladenine dioxygenase activity
B7485_RS12480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7485_RS12480	COG2169	Transcriptional regulator
B7485_RS12485	COG1477	protein flavinylation
B7485_RS12495	COG2198	Histidine kinase
B7485_RS12495	COG0642	Histidine kinase
B7485_RS12500	COG2197	response regulator
B7485_RS12505	COG0784	Response regulator, receiver
B7485_RS12505	COG2205	protein histidine kinase activity
B7485_RS12510	COG4676	Protein conserved in bacteria
B7485_RS12540	COG3234	Protein of unknown function (DUF1175)
B7485_RS12550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7485_RS12560	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS12565	COG3468	outer membrane autotransporter barrel domain protein
B7485_RS12580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7485_RS12585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7485_RS12590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7485_RS12595	COG3642	lipopolysaccharide core region biosynthetic process
B7485_RS12605	COG0584	glycerophosphoryl diester phosphodiesterase
B7485_RS12610	COG2271	Major facilitator Superfamily
B7485_RS12615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7485_RS12625	COG0247	lactate metabolic process
B7485_RS12630	COG5464	transposase or invertase
B7485_RS12700	COG0318	PFAM AMP-dependent synthetase and ligase
B7485_RS12710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B7485_RS12725	COG1169	isochorismate synthase
B7485_RS12730	COG4575	ribosome binding
B7485_RS12735	COG2153	protein acetylation
B7485_RS12775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7485_RS12780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7485_RS12790	COG0839	Belongs to the complex I subunit 6 family
B7485_RS12810	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B7485_RS12815	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B7485_RS12835	COG0583	DNA-binding transcription factor activity
B7485_RS12840	COG0436	Aminotransferase
B7485_RS12850	COG0490	domain, Protein
B7485_RS12850	COG0471	metal ion transport
B7485_RS12855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS12870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7485_RS12875	COG0857	belongs to the CobB CobQ family
B7485_RS12875	COG0280	phosphate acetyltransferase
B7485_RS12880	COG1288	antiporter activity
B7485_RS12890	COG0622	Phosphoesterase
B7485_RS12895	COG0625	glutathione transferase activity
B7485_RS12900	COG0625	glutathione transferase activity
B7485_RS12905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B7485_RS12910	COG1090	epimerase
B7485_RS12915	COG5464	transposase or invertase
B7485_RS12920	COG4598	ABC transporter
B7485_RS12925	COG4160	amino acid transport
B7485_RS12930	COG4215	(ABC) transporter
B7485_RS12935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS12945	COG0163	prenyltransferase activity
B7485_RS12950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B7485_RS12955	COG1286	toxin biosynthetic process
B7485_RS12960	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
B7485_RS12965	COG0285	dihydrofolate synthase activity
B7485_RS12975	COG0586	Pfam SNARE associated Golgi protein
B7485_RS12985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B7485_RS13005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7485_RS13020	COG3101	peptidyl-lysine hydroxylation
B7485_RS13025	COG0730	response to heat
B7485_RS13055	COG3539	Fimbrial protein
B7485_RS13060	COG3539	Fimbrial protein
B7485_RS13070	COG3539	Fimbrial protein
B7485_RS13085	COG3539	Fimbrial protein
B7485_RS13095	COG2062	phosphohistidine phosphatase, SixA
B7485_RS13110	COG3691	Protein conserved in bacteria
B7485_RS13130	COG2116	formate transmembrane transporter activity
B7485_RS13140	COG0582	viral genome integration into host DNA
B7485_RS13175	COG0477	Major facilitator Superfamily
B7485_RS13180	COG1566	PFAM secretion protein HlyD family protein
B7485_RS13185	COG2197	response regulator
B7485_RS13190	COG2198	Histidine kinase
B7485_RS13190	COG2205	protein histidine kinase activity
B7485_RS13190	COG0784	Response regulator, receiver
B7485_RS13190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS13195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7485_RS13200	COG0679	Auxin Efflux Carrier
B7485_RS13205	COG0028	Belongs to the TPP enzyme family
B7485_RS13230	COG1560	Kdo2-lipid A biosynthetic process
B7485_RS13245	COG0436	Aminotransferase
B7485_RS13255	COG3279	Response regulator of the LytR AlgR family
B7485_RS13260	COG2207	Transcriptional regulator
B7485_RS13270	COG1363	Peptidase, m42
B7485_RS13280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS13310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7485_RS13320	COG2200	EAL domain
B7485_RS13320	COG2199	diguanylate cyclase activity
B7485_RS13335	COG3415	Transposase
B7485_RS13340	COG3415	Transposase
B7485_RS13375	COG0583	DNA-binding transcription factor activity
B7485_RS13380	COG0385	Bile acid
B7485_RS13385	COG3530	Putative quorum-sensing-regulated virulence factor
B7485_RS13405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7485_RS13410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS13415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7485_RS13420	COG2190	(PTS) system
B7485_RS13440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7485_RS13450	COG4208	sulfate ABC transporter
B7485_RS13455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B7485_RS13460	COG4150	thiosulfate binding
B7485_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS13485	COG2837	iron assimilation
B7485_RS13505	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7485_RS13520	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
B7485_RS13525	COG4816	utilization protein
B7485_RS13565	COG0076	glutamate decarboxylase activity
B7485_RS13570	COG0076	glutamate decarboxylase activity
B7485_RS13575	COG0531	amino acid
B7485_RS13580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7485_RS13595	COG4819	ethanolamine utilization protein
B7485_RS13600	COG4917	ethanolamine utilization protein
B7485_RS13605	COG4810	utilization protein
B7485_RS13610	COG0281	malic enzyme
B7485_RS13610	COG0280	phosphate acetyltransferase
B7485_RS13620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7485_RS13625	COG5342	invasion associated locus B
B7485_RS13635	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS13635	COG0493	'glutamate synthase
B7485_RS13645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7485_RS13660	COG1393	Belongs to the ArsC family
B7485_RS13675	COG0400	carboxylic ester hydrolase activity
B7485_RS13685	COG2321	neutral zinc metallopeptidase
B7485_RS13695	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B7485_RS13705	COG2716	regulation of RNA biosynthetic process
B7485_RS13710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B7485_RS13715	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS13725	COG0650	Formate hydrogenlyase subunit 4
B7485_RS13730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7485_RS13735	COG4237	Hydrogenase 4 membrane
B7485_RS13740	COG0651	ATP synthesis coupled electron transport
B7485_RS13750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7485_RS13755	COG3260	NADH ubiquinone oxidoreductase 20
B7485_RS13765	COG3604	Transcriptional regulator
B7485_RS13775	COG0628	permease
B7485_RS13780	COG4783	chaperone-mediated protein folding
B7485_RS13785	COG1393	Belongs to the ArsC family
B7485_RS13795	COG2233	PERMEase
B7485_RS13810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B7485_RS13815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B7485_RS13820	COG0248	Ppx GppA phosphatase
B7485_RS13845	COG3133	Outer membrane lipoprotein
B7485_RS13860	COG0516	GMP reductase activity
B7485_RS13860	COG0517	IMP dehydrogenase activity
B7485_RS13870	COG1645	bacterial-type flagellum-dependent swarming motility
B7485_RS13885	COG2976	Protein conserved in bacteria
B7485_RS13920	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS13940	COG2975	iron-sulfur cluster assembly
B7485_RS13945	COG0633	Ferredoxin
B7485_RS13965	COG0822	iron-sulfur transferase activity
B7485_RS13985	COG0483	inositol monophosphate 1-phosphatase activity
B7485_RS13990	COG1073	alpha beta
B7485_RS13995	COG3711	transcriptional antiterminator
B7485_RS14000	COG2814	Major facilitator Superfamily
B7485_RS14005	COG0583	DNA-binding transcription factor activity
B7485_RS14035	COG2259	Doxx family
B7485_RS14040	COG2017	converts alpha-aldose to the beta-anomer
B7485_RS14045	COG1063	alcohol dehydrogenase
B7485_RS14050	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7485_RS14055	COG1129	ABC transporter
B7485_RS14060	COG1879	ABC-type sugar transport system periplasmic component
B7485_RS14065	COG0457	Tetratricopeptide repeat
B7485_RS14070	COG1940	carbohydrate kinase activity
B7485_RS14085	COG0347	Belongs to the P(II) protein family
B7485_RS14090	COG2204	response regulator
B7485_RS14095	COG3170	Tfp pilus assembly protein FimV
B7485_RS14100	COG2205	protein histidine kinase activity
B7485_RS14120	COG0560	Phosphoserine phosphatase
B7485_RS14125	COG1737	Transcriptional regulator
B7485_RS14160	COG5301	cellulose 1,4-beta-cellobiosidase activity
B7485_RS14205	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS14240	COG0681	Belongs to the peptidase S26 family
B7485_RS14250	COG3086	response to oxidative stress
B7485_RS14255	COG3026	antisigma factor binding
B7485_RS14260	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
B7485_RS14265	COG1595	DNA-templated transcription, initiation
B7485_RS14285	COG0513	Belongs to the DEAD box helicase family
B7485_RS14290	COG0583	DNA-binding transcription factor activity
B7485_RS14310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7485_RS14315	COG3118	belongs to the thioredoxin family
B7485_RS14320	COG3148	PFAM DTW domain containing protein
B7485_RS14325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7485_RS14325	COG1042	CoA-binding domain protein
B7485_RS14325	COG0045	succinate-CoA ligase (ADP-forming) activity
B7485_RS14330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7485_RS14335	COG5544	Lipoprotein
B7485_RS14340	COG0477	Major facilitator Superfamily
B7485_RS14370	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS14375	COG0564	pseudouridine synthase activity
B7485_RS14385	COG0542	response to heat
B7485_RS14395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B7485_RS14405	COG0077	Prephenate dehydratase
B7485_RS14405	COG1605	Chorismate mutase
B7485_RS14410	COG1605	Chorismate mutase
B7485_RS14410	COG0287	Prephenate dehydrogenase
B7485_RS14415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7485_RS14435	COG2885	chlorophyll binding
B7485_RS14460	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B7485_RS14465	COG4137	Cytochrome C assembly protein
B7485_RS14470	COG4536	flavin adenine dinucleotide binding
B7485_RS14485	COG0497	DNA recombination
B7485_RS14490	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS14500	COG2867	negative regulation of translational initiation
B7485_RS14515	COG0582	viral genome integration into host DNA
B7485_RS14535	COG0366	Alpha amylase catalytic
B7485_RS14545	COG0579	oxidoreductase
B7485_RS14555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7485_RS14560	COG1113	amino acid transport
B7485_RS14565	COG1802	Transcriptional regulator
B7485_RS14570	COG1652	LysM domain
B7485_RS14575	COG0401	homolog of Blt101
B7485_RS14585	COG0640	Transcriptional regulator
B7485_RS14590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7485_RS14595	COG2916	Histone family protein nucleoid-structuring protein H-NS
B7485_RS14610	COG4575	ribosome binding
B7485_RS14620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7485_RS14630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7485_RS14635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7485_RS14640	COG4175	Glycine betaine
B7485_RS14645	COG4176	ABC-type proline glycine betaine transport system permease component
B7485_RS14650	COG2113	Glycine betaine
B7485_RS14660	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7485_RS14670	COG1846	Transcriptional regulator
B7485_RS14680	COG2814	Major facilitator Superfamily
B7485_RS14695	COG1238	metal cluster binding
B7485_RS14700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS14730	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B7485_RS14750	COG1546	Belongs to the CinA family
B7485_RS14755	COG2951	lytic endotransglycosylase activity
B7485_RS14765	COG3732	PTS system glucitol sorbitol-specific
B7485_RS14775	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS14785	COG1349	DNA-binding transcription factor activity
B7485_RS14810	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B7485_RS14815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS14820	COG1609	Transcriptional regulator
B7485_RS14825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7485_RS14830	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
B7485_RS14830	COG3261	NADH dehydrogenase
B7485_RS14835	COG0650	Formate hydrogenlyase subunit 4
B7485_RS14840	COG0651	ATP synthesis coupled electron transport
B7485_RS14845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS14860	COG0375	protein maturation
B7485_RS14865	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B7485_RS14870	COG0298	carbon dioxide binding
B7485_RS14875	COG0409	Hydrogenase expression formation protein
B7485_RS14880	COG0309	Hydrogenase expression formation protein (HypE)
B7485_RS14885	COG3604	Transcriptional regulator
B7485_RS14915	COG1349	DNA-binding transcription factor activity
B7485_RS14920	COG2084	Dehydrogenase
B7485_RS14940	COG3423	Transcriptional regulator
B7485_RS14970	COG1388	LysM domain
B7485_RS14970	COG4942	peptidase
B7485_RS15025	COG2234	aminopeptidase activity
B7485_RS15060	COG0720	synthase
B7485_RS15065	COG0644	oxidoreductase
B7485_RS15070	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B7485_RS15090	COG0477	Major facilitator Superfamily
B7485_RS15095	COG0277	FAD linked oxidase domain protein
B7485_RS15105	COG0602	queuosine metabolic process
B7485_RS15140	COG3956	TIGRFAM MazG family protein
B7485_RS15145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7485_RS15160	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS15165	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS15170	COG2271	Major facilitator Superfamily
B7485_RS15175	COG0716	FMN binding
B7485_RS15180	COG0564	pseudouridine synthase activity
B7485_RS15185	COG3098	single-species biofilm formation
B7485_RS15200	COG1611	Belongs to the LOG family
B7485_RS15205	COG3385	transposase activity
B7485_RS15210	COG0814	amino acid
B7485_RS15215	COG1760	l-serine dehydratase
B7485_RS15225	COG1454	alcohol dehydrogenase
B7485_RS15230	COG0235	Class ii aldolase
B7485_RS15235	COG0738	Major facilitator superfamily
B7485_RS15255	COG1349	DNA-binding transcription factor activity
B7485_RS15265	COG2363	Small membrane protein
B7485_RS15270	COG0583	DNA-binding transcription factor activity
B7485_RS15280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7485_RS15285	COG2166	iron-sulfur cluster assembly
B7485_RS15290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B7485_RS15295	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B7485_RS15310	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7485_RS15320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7485_RS15325	COG1074	ATP-dependent DNA helicase activity
B7485_RS15335	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B7485_RS15340	COG4967	type IV pilus modification protein PilV
B7485_RS15350	COG4795	General secretion pathway protein
B7485_RS15370	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
B7485_RS15390	COG0861	Integral membrane protein TerC family
B7485_RS15400	COG0667	Aldo Keto reductase
B7485_RS15420	COG1609	Transcriptional regulator
B7485_RS15430	COG0583	DNA-binding transcription factor activity
B7485_RS15435	COG1794	racemase activity, acting on amino acids and derivatives
B7485_RS15440	COG2814	Major facilitator Superfamily
B7485_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS15455	COG0183	Belongs to the thiolase family
B7485_RS15460	COG0814	amino acid
B7485_RS15465	COG2771	luxR family
B7485_RS15500	COG4974	Belongs to the 'phage' integrase family
B7485_RS15510	COG4942	peptidase
B7485_RS15515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7485_RS15520	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B7485_RS15525	COG2080	2 iron, 2 sulfur cluster binding
B7485_RS15550	COG2233	PERMEase
B7485_RS15580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B7485_RS15585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7485_RS15595	COG0716	FMN binding
B7485_RS15615	COG1272	protein, Hemolysin III
B7485_RS15625	COG2723	6-phospho-beta-galactosidase activity
B7485_RS15630	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS15655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7485_RS15660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7485_RS15665	COG0006	proline dipeptidase activity
B7485_RS15685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B7485_RS15700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7485_RS15715	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7485_RS15715	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7485_RS15720	COG1703	isobutyryl-CoA mutase activity
B7485_RS15725	COG1024	Enoyl-CoA hydratase
B7485_RS15730	COG0427	acetyl-CoA hydrolase
B7485_RS15735	COG0583	DNA-binding transcription factor activity
B7485_RS15740	COG2968	Membrane
B7485_RS15750	COG0668	transmembrane transport
B7485_RS15755	COG0191	fructose-bisphosphate aldolase activity
B7485_RS15790	COG1122	ATPase activity
B7485_RS15795	COG1122	ATPase activity
B7485_RS15800	COG1072	(Pantothenic acid kinase))
B7485_RS15810	COG1494	fructose-1,6-bisphosphatase
B7485_RS15815	COG1063	alcohol dehydrogenase
B7485_RS15825	COG0330	HflC and HflK could
B7485_RS15830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7485_RS15835	COG0501	Belongs to the peptidase M48B family
B7485_RS15870	COG2814	Major facilitator Superfamily
B7485_RS15880	COG2356	endonuclease I
B7485_RS15885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7485_RS15905	COG2805	Type II/IV secretion system protein
B7485_RS15910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B7485_RS15915	COG0762	integral membrane protein
B7485_RS15930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7485_RS15940	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B7485_RS15960	COG0252	asparaginase activity
B7485_RS15970	COG3171	Protein conserved in bacteria
B7485_RS15980	COG1194	a g-specific adenine glycosylase
B7485_RS15995	COG2211	Major facilitator Superfamily
B7485_RS16000	COG1982	Orn Lys Arg decarboxylase major
B7485_RS16005	COG1811	Na channel or pump
B7485_RS16045	COG1620	l-lactate permease
B7485_RS16055	COG3193	protein, possibly involved in utilization of glycolate and propanediol
B7485_RS16065	COG0277	FAD linked oxidase domain protein
B7485_RS16075	COG2186	Transcriptional regulator
B7485_RS16095	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B7485_RS16100	COG0306	phosphate transporter
B7485_RS16105	COG0754	glutathionylspermidine amidase activity
B7485_RS16110	COG0625	glutathione transferase activity
B7485_RS16115	COG0298	carbon dioxide binding
B7485_RS16125	COG1773	rubredoxin
B7485_RS16130	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B7485_RS16135	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B7485_RS16140	COG5557	Pfam Polysulphide reductase, NrfD
B7485_RS16145	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS16150	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
B7485_RS16165	COG0667	Aldo Keto reductase
B7485_RS16175	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS16180	COG0848	biopolymer transport protein
B7485_RS16185	COG0811	peptide transport
B7485_RS16190	COG0626	cystathionine gamma-synthase activity
B7485_RS16195	COG0586	Pfam SNARE associated Golgi protein
B7485_RS16200	COG2207	Transcriptional regulator
B7485_RS16205	COG1979	alcohol dehydrogenase
B7485_RS16210	COG0656	L-ascorbic acid biosynthetic process
B7485_RS16220	COG4238	major outer membrane lipoprotein
B7485_RS16230	COG2132	Multicopper oxidase
B7485_RS16235	COG0204	Acyl-transferase
B7485_RS16240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7485_RS16245	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B7485_RS16250	COG3111	PFAM Bacterial OB fold (BOF) protein
B7485_RS16255	COG0745	RESPONSE REGULATOR receiver
B7485_RS16260	COG0642	Histidine kinase
B7485_RS16280	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7485_RS16285	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B7485_RS16290	COG0187	DNA topoisomerase II activity
B7485_RS16295	COG3150	esterase
B7485_RS16300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7485_RS16305	COG3151	Protein conserved in bacteria
B7485_RS16310	COG0494	nUDIX hydrolase
B7485_RS16315	COG1538	Outer membrane efflux protein
B7485_RS16325	COG0754	glutathionylspermidine amidase activity
B7485_RS16330	COG3384	dioxygenase
B7485_RS16345	COG2960	long-chain fatty acid transporting porin activity
B7485_RS16395	COG3025	triphosphatase activity
B7485_RS16400	COG4991	sh3 domain protein
B7485_RS16415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B7485_RS16435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS16450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B7485_RS16455	COG0358	DNA primase activity
B7485_RS16460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7485_RS16485	COG1695	Transcriptional regulator
B7485_RS16505	COG1609	Transcriptional regulator
B7485_RS16510	COG3250	beta-galactosidase activity
B7485_RS16515	COG2731	YhcH YjgK YiaL family protein
B7485_RS16520	COG0531	amino acid
B7485_RS16530	COG3408	Glycogen debranching enzyme
B7485_RS16530	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
B7485_RS16535	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7485_RS16535	COG1902	pentaerythritol trinitrate reductase activity
B7485_RS16540	COG5499	transcription regulator containing HTH domain
B7485_RS16545	COG4680	protein conserved in bacteria
B7485_RS16555	COG1451	nucleotide metabolic process
B7485_RS16560	COG2949	membrane
B7485_RS16565	COG0673	inositol 2-dehydrogenase activity
B7485_RS16570	COG0861	Integral membrane protein TerC family
B7485_RS16585	COG2721	sulfolactate sulfo-lyase activity
B7485_RS16595	COG2271	Major facilitator Superfamily
B7485_RS16625	COG2186	Transcriptional regulator
B7485_RS16630	COG0586	Pfam SNARE associated Golgi protein
B7485_RS16645	COG4575	ribosome binding
B7485_RS16650	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
B7485_RS16660	COG2259	Doxx family
B7485_RS16665	COG0435	Glutathione S-transferase
B7485_RS16670	COG3152	Membrane
B7485_RS16675	COG0583	DNA-binding transcription factor activity
B7485_RS16680	COG1741	Belongs to the pirin family
B7485_RS16695	COG0814	amino acid
B7485_RS16700	COG1760	l-serine dehydratase
B7485_RS16705	COG0251	oxidation-reduction process
B7485_RS16710	COG1882	Formate acetyltransferase
B7485_RS16715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7485_RS16725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7485_RS16730	COG0583	DNA-binding transcription factor activity
B7485_RS16760	COG1929	Belongs to the glycerate kinase type-1 family
B7485_RS16765	COG2084	Dehydrogenase
B7485_RS16775	COG2271	Major facilitator Superfamily
B7485_RS16780	COG2721	sulfolactate sulfo-lyase activity
B7485_RS16785	COG1349	DNA-binding transcription factor activity
B7485_RS16795	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS16805	COG3716	PTS system mannose fructose sorbose family IID component
B7485_RS16810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS16830	COG3715	PTS system
B7485_RS16835	COG3716	PTS system mannose fructose sorbose family IID component
B7485_RS16840	COG0363	glucosamine-6-phosphate deaminase activity
B7485_RS16860	COG3121	Chaperone
B7485_RS16880	COG3539	Fimbrial protein
B7485_RS16885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B7485_RS16905	COG2823	Periplasmic or secreted lipoprotein
B7485_RS16910	COG0701	Predicted permease
B7485_RS16915	COG0702	epimerase
B7485_RS16920	COG0693	protein deglycase activity
B7485_RS16935	COG3153	acetyltransferase
B7485_RS16940	COG3154	lipid carrier protein
B7485_RS16945	COG0826	peptidase U32
B7485_RS16950	COG0826	peptidase U32
B7485_RS16955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7485_RS16960	COG0814	amino acid
B7485_RS16965	COG0513	Belongs to the DEAD box helicase family
B7485_RS17005	COG0195	Participates in both transcription termination and antitermination
B7485_RS17035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7485_RS17045	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7485_RS17050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7485_RS17060	COG1534	Rna-binding protein
B7485_RS17065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7485_RS17070	COG2027	D-alanyl-D-alanine carboxypeptidase
B7485_RS17080	COG0697	spore germination
B7485_RS17095	COG0142	geranyltranstransferase activity
B7485_RS17100	COG3423	Transcriptional regulator
B7485_RS17110	COG5007	Belongs to the BolA IbaG family
B7485_RS17115	COG3113	response to antibiotic
B7485_RS17120	COG2854	intermembrane phospholipid transfer
B7485_RS17125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7485_RS17130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7485_RS17135	COG1127	ABC transporter
B7485_RS17140	COG0530	calcium, potassium:sodium antiporter activity
B7485_RS17150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B7485_RS17155	COG3117	lipopolysaccharide transmembrane transporter activity
B7485_RS17160	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B7485_RS17165	COG1137	ATPase activity
B7485_RS17170	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B7485_RS17175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B7485_RS17190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS17195	COG0515	serine threonine protein kinase
B7485_RS17205	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
B7485_RS17210	COG0784	Response regulator, receiver
B7485_RS17210	COG2198	Histidine kinase
B7485_RS17210	COG5002	protein histidine kinase activity
B7485_RS17215	COG1242	4 iron, 4 sulfur cluster binding
B7485_RS17220	COG0067	glutamate synthase
B7485_RS17220	COG0069	glutamate synthase activity
B7485_RS17220	COG0070	glutamate synthase
B7485_RS17225	COG0493	'glutamate synthase
B7485_RS17230	COG4804	nuclease activity
B7485_RS17245	COG2731	YhcH YjgK YiaL family protein
B7485_RS17280	COG3069	C4-dicarboxylate transmembrane transporter activity
B7485_RS17285	COG2969	positive regulation of protein catabolic process
B7485_RS17290	COG0625	glutathione transferase activity
B7485_RS17305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B7485_RS17310	COG3105	Protein conserved in bacteria
B7485_RS17320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7485_RS17340	COG2732	(Barnase) inhibitor
B7485_RS17360	COG0583	DNA-binding transcription factor activity
B7485_RS17365	COG0312	modulator of DNA gyrase
B7485_RS17370	COG3164	Protein of unknown function
B7485_RS17375	COG1530	ribonuclease E activity
B7485_RS17385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B7485_RS17390	COG1792	Involved in formation and maintenance of cell shape
B7485_RS17395	COG1077	Cell shape determining protein MreB Mrl
B7485_RS17400	COG2200	EAL domain
B7485_RS17400	COG2199	diguanylate cyclase activity
B7485_RS17405	COG0604	alcohol dehydrogenase
B7485_RS17410	COG0511	ligase activity, forming carbon-carbon bonds
B7485_RS17415	COG0439	Biotin carboxylase
B7485_RS17420	COG3924	membrane
B7485_RS17425	COG4145	pantothenate transmembrane transporter activity
B7485_RS17445	COG2189	Belongs to the N(4) N(6)-methyltransferase family
B7485_RS17460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7485_RS17475	COG4597	amino acid ABC transporter
B7485_RS17480	COG0765	amino acid transport
B7485_RS17485	COG1126	abc transporter atp-binding protein
B7485_RS17525	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B7485_RS17545	COG0551	DNA topoisomerase type I activity
B7485_RS17555	COG0758	DNA mediated transformation
B7485_RS17575	COG0569	domain protein
B7485_RS17585	COG3436	PFAM IS66 Orf2 family protein
B7485_RS17590	COG4372	Transposase
B7485_RS17630	COG0201	protein transport
B7485_RS17720	COG0089	rRNA binding
B7485_RS17790	COG2964	Protein conserved in bacteria
B7485_RS17795	COG0545	Peptidyl-prolyl cis-trans isomerase
B7485_RS17805	COG1047	Peptidyl-prolyl cis-trans
B7485_RS17810	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
B7485_RS17825	COG0488	(ABC) transporter
B7485_RS17830	COG0429	hydrolase of the alpha beta-hydrolase fold
B7485_RS17840	COG3954	Phosphoribulokinase
B7485_RS17845	COG1765	OsmC-like protein
B7485_RS17850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7485_RS17855	COG1289	transmembrane transporter activity
B7485_RS17865	COG0512	Glutamine amidotransferase of anthranilate synthase
B7485_RS17870	COG2184	nucleotidyltransferase activity
B7485_RS17880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7485_RS17895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7485_RS17900	COG2146	nitrite reductase [NAD(P)H] activity
B7485_RS17905	COG2116	formate transmembrane transporter activity
B7485_RS17925	COG2222	sugar isomerase
B7485_RS17930	COG1082	Xylose isomerase domain protein TIM barrel
B7485_RS17945	COG0626	cystathionine gamma-synthase activity
B7485_RS17960	COG1735	metal-dependent hydrolase with the TIM-barrel fold
B7485_RS17965	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B7485_RS17970	COG3457	Alanine racemase
B7485_RS17980	COG2188	Transcriptional regulator
B7485_RS17995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7485_RS18000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B7485_RS18005	COG3266	domain, Protein
B7485_RS18020	COG4796	Type ii and iii secretion system protein
B7485_RS18035	COG3166	PFAM Fimbrial assembly family protein
B7485_RS18040	COG4972	Pilus assembly protein
B7485_RS18045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B7485_RS18050	COG0494	nUDIX hydrolase
B7485_RS18060	COG1011	Hydrolase
B7485_RS18065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B7485_RS18075	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B7485_RS18095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7485_RS18100	COG2183	response to ionizing radiation
B7485_RS18105	COG1918	ferrous iron import across plasma membrane
B7485_RS18120	COG5464	transposase or invertase
B7485_RS18155	COG2610	gluconate transmembrane transporter activity
B7485_RS18160	COG1640	4-alpha-glucanotransferase
B7485_RS18165	COG0058	SHG alpha-glucan phosphorylase activity
B7485_RS18180	COG1690	Belongs to the RtcB family
B7485_RS18185	COG4650	regulator
B7485_RS18190	COG1349	DNA-binding transcription factor activity
B7485_RS18205	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7485_RS18215	COG3385	transposase activity
B7485_RS18220	COG0058	SHG alpha-glucan phosphorylase activity
B7485_RS18245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B7485_RS18250	COG2095	MarC family integral membrane protein
B7485_RS18255	COG2610	gluconate transmembrane transporter activity
B7485_RS18260	COG3265	gluconokinase activity
B7485_RS18265	COG1609	Transcriptional regulator
B7485_RS18270	COG1741	Belongs to the pirin family
B7485_RS18275	COG0673	inositol 2-dehydrogenase activity
B7485_RS18280	COG1247	-acetyltransferase
B7485_RS18285	COG0405	Gamma-glutamyltransferase
B7485_RS18295	COG0584	glycerophosphoryl diester phosphodiesterase
B7485_RS18320	COG0410	ABC transporter
B7485_RS18325	COG0411	ABC transporter
B7485_RS18330	COG4177	L-phenylalanine transmembrane transporter activity
B7485_RS18335	COG0559	Belongs to the binding-protein-dependent transport system permease family
B7485_RS18340	COG0683	leucine binding
B7485_RS18345	COG0456	acetyltransferase
B7485_RS18350	COG0683	leucine binding
B7485_RS18355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7485_RS18360	COG2177	Part of the ABC transporter FtsEX involved in
B7485_RS18365	COG2884	Cell division ATP-binding protein ftsE
B7485_RS18370	COG0552	protein localization to endoplasmic reticulum
B7485_RS18375	COG0742	ribosomal rna small subunit methyltransferase
B7485_RS18380	COG3776	membrane
B7485_RS18390	COG3714	YhhN family
B7485_RS18405	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B7485_RS18420	COG0628	permease
B7485_RS18425	COG2091	lysine biosynthetic process via aminoadipic acid
B7485_RS18430	COG0747	negative chemotaxis
B7485_RS18435	COG0601	transmembrane transport
B7485_RS18440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7485_RS18470	COG0842	Transport permease protein
B7485_RS18475	COG0842	Transport permease protein
B7485_RS18475	COG1129	ABC transporter
B7485_RS18480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS18565	COG2081	HI0933 family
B7485_RS18570	COG0306	phosphate transporter
B7485_RS18580	COG0589	response to stress
B7485_RS18600	COG0339	signal peptide processing
B7485_RS18605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B7485_RS18610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7485_RS18620	COG0640	Transcriptional regulator
B7485_RS18625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7485_RS18630	COG1393	Belongs to the ArsC family
B7485_RS18655	COG3065	identical protein binding
B7485_RS18680	COG3247	response to pH
B7485_RS18685	COG2771	luxR family
B7485_RS18695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7485_RS18715	COG1278	Cold shock
B7485_RS18735	COG2885	chlorophyll binding
B7485_RS18740	COG0243	molybdopterin cofactor binding
B7485_RS18745	COG0456	acetyltransferase
B7485_RS18750	COG2818	Glycosylase
B7485_RS18755	COG5571	outer membrane autotransporter
B7485_RS18760	COG2223	nitrite transmembrane transporter activity
B7485_RS18765	COG2194	sulfuric ester hydrolase activity
B7485_RS18775	COG0747	negative chemotaxis
B7485_RS18780	COG0601	transmembrane transport
B7485_RS18785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7485_RS18790	COG0444	Belongs to the ABC transporter superfamily
B7485_RS18795	COG4608	Belongs to the ABC transporter superfamily
B7485_RS18800	COG0814	amino acid
B7485_RS18845	COG2194	sulfuric ester hydrolase activity
B7485_RS18870	COG1215	transferase activity, transferring glycosyl groups
B7485_RS18880	COG1215	transferase activity, transferring glycosyl groups
B7485_RS18885	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B7485_RS18905	COG2200	EAL domain
B7485_RS18905	COG2199	diguanylate cyclase activity
B7485_RS18915	COG0612	Peptidase, M16
B7485_RS18925	COG2200	EAL domain
B7485_RS18930	COG2982	Protein involved in outer membrane biogenesis
B7485_RS18935	COG0477	Major facilitator Superfamily
B7485_RS18940	COG1295	ribonuclease BN
B7485_RS18945	COG0583	DNA-binding transcription factor activity
B7485_RS18950	COG2197	response regulator
B7485_RS18955	COG3385	transposase activity
B7485_RS18975	COG1858	cytochrome C peroxidase
B7485_RS18990	COG2207	Transcriptional regulator
B7485_RS19025	COG3274	enterobacterial common antigen metabolic process
B7485_RS19030	COG4682	membrane
B7485_RS19035	COG4682	membrane
B7485_RS19040	COG1070	Carbohydrate kinase
B7485_RS19060	COG4214	carbohydrate transport
B7485_RS19070	COG2992	FlgJ-related protein
B7485_RS19075	COG0366	Alpha amylase catalytic
B7485_RS19080	COG3977	Valine--pyruvate aminotransferase
B7485_RS19085	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7485_RS19090	COG1414	Transcriptional regulator
B7485_RS19115	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B7485_RS19120	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B7485_RS19125	COG1070	Carbohydrate kinase
B7485_RS19130	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B7485_RS19135	COG3623	hexulose-6-phosphate isomerase
B7485_RS19140	COG0235	Class ii aldolase
B7485_RS19150	COG2211	Major facilitator Superfamily
B7485_RS19160	COG3713	MltA-interacting MipA family protein
B7485_RS19180	COG1566	PFAM secretion protein HlyD family protein
B7485_RS19195	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS19200	COG1454	alcohol dehydrogenase
B7485_RS19205	COG3276	selenocysteine insertion sequence binding
B7485_RS19215	COG0625	glutathione transferase activity
B7485_RS19220	COG1566	PFAM secretion protein HlyD family protein
B7485_RS19230	COG2213	PTS system mannitol-specific
B7485_RS19230	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS19240	COG3722	fumarate hydratase activity
B7485_RS19270	COG1620	l-lactate permease
B7485_RS19275	COG2186	Transcriptional regulator
B7485_RS19285	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B7485_RS19290	COG1045	serine acetyltransferase
B7485_RS19305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7485_RS19310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7485_RS19320	COG4942	peptidase
B7485_RS19325	COG2861	carbohydrate metabolic process
B7485_RS19345	COG0156	8-amino-7-oxononanoate synthase activity
B7485_RS19360	COG0859	PFAM glycosyl transferase family 9
B7485_RS19365	COG0859	PFAM glycosyl transferase family 9
B7485_RS19385	COG3642	lipopolysaccharide core region biosynthetic process
B7485_RS19395	COG0515	serine threonine protein kinase
B7485_RS19400	COG0438	transferase activity, transferring glycosyl groups
B7485_RS19405	COG0859	PFAM glycosyl transferase family 9
B7485_RS19415	COG1519	Transferase
B7485_RS19445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7485_RS19470	COG1561	YicC-like family, N-terminal region
B7485_RS19480	COG3645	SOS response
B7485_RS19485	COG2860	membrane
B7485_RS19495	COG0194	GDP metabolic process
B7485_RS19505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7485_RS19510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7485_RS19515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7485_RS19520	COG0786	glutamate:sodium symporter activity
B7485_RS19525	COG2233	PERMEase
B7485_RS19530	COG2982	Protein involved in outer membrane biogenesis
B7485_RS19535	COG1501	Belongs to the glycosyl hydrolase 31 family
B7485_RS19550	COG0582	viral genome integration into host DNA
B7485_RS19700	COG2252	PERMEase
B7485_RS19710	COG2271	Major facilitator Superfamily
B7485_RS19715	COG2271	Major facilitator Superfamily
B7485_RS19720	COG3851	Histidine kinase
B7485_RS19725	COG2197	response regulator
B7485_RS19730	COG0440	acetolactate synthase activity
B7485_RS19735	COG0028	Belongs to the TPP enzyme family
B7485_RS19750	COG2814	Major facilitator Superfamily
B7485_RS19755	COG0641	radical SAM
B7485_RS19765	COG2149	membrane
B7485_RS19780	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7485_RS19785	COG2207	Transcriptional regulator
B7485_RS19800	COG2188	Transcriptional regulator
B7485_RS19820	COG5645	(Lipo)protein
B7485_RS19825	COG0823	Involved in the tonB-independent uptake of proteins
B7485_RS19835	COG2271	Major facilitator Superfamily
B7485_RS19845	COG0800	Aldolase
B7485_RS19850	COG3734	2-keto-3-deoxy-galactonokinase
B7485_RS19855	COG2186	Transcriptional regulator
B7485_RS19865	COG0561	phosphatase activity
B7485_RS19870	COG3753	Protein conserved in bacteria
B7485_RS19875	COG0187	DNA topoisomerase II activity
B7485_RS19885	COG0592	DNA-directed DNA polymerase activity
B7485_RS19940	COG0814	amino acid
B7485_RS19965	COG2091	lysine biosynthetic process via aminoadipic acid
B7485_RS19970	COG0431	NADPH-dependent FMN reductase
B7485_RS19975	COG2252	PERMEase
B7485_RS19980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7485_RS19995	COG3436	PFAM IS66 Orf2 family protein
B7485_RS20000	COG4372	Transposase
B7485_RS20005	COG3196	Protein conserved in bacteria
B7485_RS20010	COG0363	glucosamine-6-phosphate deaminase activity
B7485_RS20025	COG2723	6-phospho-beta-galactosidase activity
B7485_RS20030	COG2190	(PTS) system
B7485_RS20030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS20030	COG1263	PTS System
B7485_RS20035	COG3711	transcriptional antiterminator
B7485_RS20040	COG0704	Plays a role in the regulation of phosphate uptake
B7485_RS20045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7485_RS20050	COG0581	inorganic phosphate transmembrane transporter activity
B7485_RS20055	COG0573	inorganic phosphate transmembrane transporter activity
B7485_RS20060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7485_RS20100	COG3385	transposase activity
B7485_RS20155	COG3312	ion transport
B7485_RS20170	COG0716	FMN binding
B7485_RS20175	COG1522	sequence-specific DNA binding
B7485_RS20195	COG3385	transposase activity
B7485_RS20210	COG1129	ABC transporter
B7485_RS20225	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7485_RS20235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS20240	COG1609	Transcriptional regulator
B7485_RS20245	COG0477	Major facilitator Superfamily
B7485_RS20250	COG2186	Transcriptional regulator
B7485_RS20290	COG3085	chromosome segregation
B7485_RS20295	COG0606	chelatase, subunit chli
B7485_RS20315	COG3978	acetolactate synthase activity
B7485_RS20320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7485_RS20330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7485_RS20335	COG0583	DNA-binding transcription factor activity
B7485_RS20345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7485_RS20350	COG0210	DNA helicase
B7485_RS20365	COG3118	belongs to the thioredoxin family
B7485_RS20375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B7485_RS20380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7485_RS20385	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
B7485_RS20390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B7485_RS20395	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B7485_RS20400	COG1088	dTDP-glucose 4,6-dehydratase activity
B7485_RS20405	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B7485_RS20410	COG0456	acetyltransferase
B7485_RS20415	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7485_RS20420	COG2244	polysaccharide biosynthetic process
B7485_RS20440	COG1113	amino acid transport
B7485_RS20465	COG0641	radical SAM
B7485_RS20475	COG3071	HemY protein
B7485_RS20480	COG2959	enzyme of heme biosynthesis
B7485_RS20485	COG1587	Uroporphyrinogen-III synthase
B7485_RS20495	COG3072	Adenylate cyclase
B7485_RS20525	COG5567	small periplasmic lipoprotein
B7485_RS20535	COG3159	Protein conserved in bacteria
B7485_RS20545	COG1011	Hydrolase
B7485_RS20550	COG0210	DNA helicase
B7485_RS20555	COG3698	Phosphodiester glycosidase
B7485_RS20560	COG3385	transposase activity
B7485_RS20565	COG3698	Phosphodiester glycosidase
B7485_RS20570	COG0598	Magnesium transport protein CorA
B7485_RS20585	COG2962	Rard protein
B7485_RS20590	COG2050	protein possibly involved in aromatic compounds catabolism
B7485_RS20595	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
B7485_RS20600	COG0514	ATP-dependent DNA helicase (RecQ)
B7485_RS20605	COG1280	lysine exporter protein (LysE YggA)
B7485_RS20610	COG1280	lysine exporter protein (LysE YggA)
B7485_RS20615	COG2267	carboxylic ester hydrolase activity
B7485_RS20620	COG0561	phosphatase activity
B7485_RS20625	COG0697	spore germination
B7485_RS20630	COG0583	DNA-binding transcription factor activity
B7485_RS20640	COG0412	Dienelactone hydrolase
B7485_RS20645	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
B7485_RS20650	COG1322	Protein conserved in bacteria
B7485_RS20660	COG3165	ubiquinone biosynthetic process from chorismate
B7485_RS20670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7485_RS20675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7485_RS20680	COG0805	protein transport
B7485_RS20690	COG0250	Participates in transcription elongation, termination and antitermination
B7485_RS20700	COG0543	2 iron, 2 sulfur cluster binding
B7485_RS20720	COG1739	Uncharacterized protein family UPF0029
B7485_RS20725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7485_RS20730	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
B7485_RS20760	COG1763	Mo-molybdopterin cofactor biosynthetic process
B7485_RS20765	COG0746	molybdenum cofactor guanylyltransferase activity
B7485_RS20770	COG3084	Protein conserved in bacteria
B7485_RS20785	COG5339	Protein conserved in bacteria
B7485_RS20790	COG0204	Acyl-transferase
B7485_RS20800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7485_RS20800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7485_RS20815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7485_RS20825	COG2204	response regulator
B7485_RS20830	COG3852	Histidine kinase
B7485_RS20840	COG0174	glutamine synthetase
B7485_RS20845	COG1217	gtp-binding protein TYPA
B7485_RS20850	COG2188	Transcriptional regulator
B7485_RS20855	COG1082	Xylose isomerase domain protein TIM barrel
B7485_RS20860	COG2271	Major facilitator Superfamily
B7485_RS20875	COG2211	Major facilitator Superfamily
B7485_RS20885	COG1501	Belongs to the glycosyl hydrolase 31 family
B7485_RS20890	COG2017	converts alpha-aldose to the beta-anomer
B7485_RS20895	COG2942	2-epimerase
B7485_RS20910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7485_RS20915	COG1349	DNA-binding transcription factor activity
B7485_RS20920	COG1011	Hydrolase
B7485_RS20935	COG0456	acetyltransferase
B7485_RS20960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7485_RS20965	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7485_RS20975	COG2864	formate dehydrogenase
B7485_RS20980	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS21000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS21000	COG3711	transcriptional antiterminator
B7485_RS21005	COG1363	Peptidase, m42
B7485_RS21010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7485_RS21055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7485_RS21070	COG2258	MOSC domain
B7485_RS21075	COG2205	protein histidine kinase activity
B7485_RS21080	COG0745	RESPONSE REGULATOR receiver
B7485_RS21085	COG3678	ATP-independent chaperone mediated protein folding
B7485_RS21100	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B7485_RS21125	COG3691	Protein conserved in bacteria
B7485_RS21130	COG0589	response to stress
B7485_RS21140	COG1494	fructose-1,6-bisphosphatase
B7485_RS21165	COG1575	Belongs to the MenA family. Type 1 subfamily
B7485_RS21180	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B7485_RS21185	COG1609	Transcriptional regulator
B7485_RS21190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7485_RS21200	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
B7485_RS21210	COG0626	cystathionine gamma-synthase activity
B7485_RS21215	COG0527	aspartate kinase activity
B7485_RS21215	COG0460	homoserine dehydrogenase
B7485_RS21220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B7485_RS21230	COG0697	spore germination
B7485_RS21235	COG3738	Protein conserved in bacteria
B7485_RS21255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21265	COG1882	Formate acetyltransferase
B7485_RS21270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B7485_RS21275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7485_RS21280	COG2207	Transcriptional regulator
B7485_RS21285	COG2194	sulfuric ester hydrolase activity
B7485_RS21315	COG3385	transposase activity
B7485_RS21320	COG4948	Mandelate Racemase Muconate Lactonizing
B7485_RS21340	COG0583	DNA-binding transcription factor activity
B7485_RS21350	COG1309	transcriptional regulator
B7485_RS21365	COG4206	TonB-dependent receptor
B7485_RS21370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7485_RS21400	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B7485_RS21400	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B7485_RS21435	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7485_RS21440	COG0250	Participates in transcription elongation, termination and antitermination
B7485_RS21475	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B7485_RS21485	COG2104	thiamine diphosphate biosynthetic process
B7485_RS21490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7485_RS21525	COG3068	Protein conserved in bacteria
B7485_RS21540	COG3678	ATP-independent chaperone mediated protein folding
B7485_RS21545	COG4191	Histidine kinase
B7485_RS21550	COG2204	response regulator
B7485_RS21555	COG0151	Belongs to the GarS family
B7485_RS21585	COG0456	acetyltransferase
B7485_RS21600	COG2224	Isocitrate lyase
B7485_RS21615	COG1414	Transcriptional regulator
B7485_RS21620	COG1410	methionine synthase
B7485_RS21620	COG0646	methionine synthase
B7485_RS21625	COG1283	sodium-dependent phosphate transmembrane transporter activity
B7485_RS21685	COG3592	Divergent 4Fe-4S mono-cluster
B7485_RS21700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B7485_RS21705	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS21705	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B7485_RS21710	COG3647	Membrane
B7485_RS21715	COG2211	Major facilitator Superfamily
B7485_RS21720	COG1486	melibiose metabolic process
B7485_RS21725	COG2169	Transcriptional regulator
B7485_RS21730	COG1982	Orn Lys Arg decarboxylase major
B7485_RS21735	COG2207	Transcriptional regulator
B7485_RS21740	COG0531	amino acid
B7485_RS21745	COG2194	sulfuric ester hydrolase activity
B7485_RS21750	COG0745	RESPONSE REGULATOR receiver
B7485_RS21755	COG0642	Histidine kinase
B7485_RS21765	COG0477	Major facilitator Superfamily
B7485_RS21775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B7485_RS21780	COG2824	Alkylphosphonate utilization operon protein PhnA
B7485_RS21785	COG2764	glyoxalase bleomycin resistance protein dioxygenase
B7485_RS21795	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B7485_RS21800	COG3639	organic phosphonate transmembrane transporter activity
B7485_RS21820	COG2207	Transcriptional regulator
B7485_RS21825	COG0789	Transcriptional regulator
B7485_RS21830	COG2252	PERMEase
B7485_RS21835	COG0025	NhaP-type Na H and K H
B7485_RS21840	COG1357	PFAM Pentapeptide repeats (8 copies)
B7485_RS21850	COG3162	membrane
B7485_RS21855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7485_RS21865	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
B7485_RS21870	COG0437	4 iron, 4 sulfur cluster binding
B7485_RS21875	COG3301	Polysulphide reductase, NrfD
B7485_RS21880	COG1138	Cytochrome C-type biogenesis protein
B7485_RS21885	COG3088	subunit of a heme lyase
B7485_RS21890	COG4235	cytochrome complex assembly
B7485_RS21895	COG1301	dicarboxylic acid transport
B7485_RS21900	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B7485_RS21930	COG0629	single-stranded DNA binding
B7485_RS21935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7485_RS21940	COG2315	Protein conserved in bacteria
B7485_RS21945	COG0432	Pfam Uncharacterised protein family UPF0047
B7485_RS21950	COG3700	Belongs to the class B bacterial acid phosphatase family
B7485_RS21960	COG1448	Aminotransferase
B7485_RS21965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7485_RS21970	COG0305	Participates in initiation and elongation during chromosome replication
B7485_RS21975	COG0604	alcohol dehydrogenase
B7485_RS21985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7485_RS22005	COG0735	belongs to the Fur family
B7485_RS22010	COG3237	CsbD-like
B7485_RS22015	COG0534	Mate efflux family protein
B7485_RS22025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B7485_RS22065	COG2182	Extracellular solute-binding protein
B7485_RS22070	COG1175	transmembrane transport
B7485_RS22075	COG3833	ABC-type maltose transport systems, permease component
B7485_RS22080	COG2814	Major facilitator Superfamily
B7485_RS22080	COG0477	Major facilitator Superfamily
B7485_RS22095	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7485_RS22120	COG0527	aspartate kinase activity
B7485_RS22125	COG4372	Transposase
B7485_RS22130	COG3436	PFAM IS66 Orf2 family protein
B7485_RS22150	COG3366	ferrous iron transmembrane transporter activity
B7485_RS22155	COG0700	Nucleoside recognition
B7485_RS22160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B7485_RS22165	COG0583	DNA-binding transcription factor activity
B7485_RS22190	COG2186	Transcriptional regulator
B7485_RS22195	COG0246	Mannitol dehydrogenase
B7485_RS22205	COG2610	gluconate transmembrane transporter activity
B7485_RS22210	COG3539	Fimbrial protein
B7485_RS22215	COG3539	Fimbrial protein
B7485_RS22220	COG3539	Fimbrial protein
B7485_RS22225	COG3188	usher protein
B7485_RS22230	COG3121	Chaperone
B7485_RS22235	COG3539	Fimbrial protein
B7485_RS22245	COG4974	Belongs to the 'phage' integrase family
B7485_RS22255	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B7485_RS22275	COG1349	DNA-binding transcription factor activity
B7485_RS22280	COG0440	acetolactate synthase activity
B7485_RS22320	COG0582	viral genome integration into host DNA
B7485_RS22330	COG1064	alcohol dehydrogenase
B7485_RS22335	COG0433	COG0433 Predicted ATPase
B7485_RS22340	COG0795	lipopolysaccharide-transporting ATPase activity
B7485_RS22345	COG0795	lipopolysaccharide-transporting ATPase activity
B7485_RS22355	COG2927	DNA polymerase III (CHI subunit)
B7485_RS22365	COG4269	membrane
B7485_RS22370	COG0456	acetyltransferase
B7485_RS22375	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
B7485_RS22395	COG2731	YhcH YjgK YiaL family protein
B7485_RS22400	COG1309	transcriptional regulator
B7485_RS22405	COG1028	Short-chain dehydrogenase reductase Sdr
B7485_RS22410	COG0251	oxidation-reduction process
B7485_RS22430	COG0251	oxidation-reduction process
B7485_RS22435	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7485_RS22445	COG1609	Transcriptional regulator
B7485_RS22450	COG1263	PTS System
B7485_RS22450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7485_RS22455	COG0366	Alpha amylase catalytic
B7485_RS22460	COG1328	CTP reductase activity
B7485_RS22465	COG0602	queuosine metabolic process
B7485_RS22470	COG3783	Cytochrome b(562)
B7485_RS22475	COG0312	modulator of DNA gyrase
B7485_RS22485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7485_RS22505	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7485_RS22510	COG1129	ABC transporter
B7485_RS22520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B7485_RS22525	COG2105	PFAM AIG2 family protein
B7485_RS22530	COG2911	Protein conserved in bacteria
B7485_RS22535	COG0729	surface antigen
B7485_RS22545	COG1253	flavin adenine dinucleotide binding
B7485_RS22555	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
B7485_RS22570	COG0737	Belongs to the 5'-nucleotidase family
B7485_RS22575	COG1733	regulation of RNA biosynthetic process
B7485_RS22580	COG0702	epimerase
B7485_RS22585	COG0697	spore germination
B7485_RS22595	COG1113	amino acid transport
B7485_RS22600	COG0545	Peptidyl-prolyl cis-trans isomerase
B7485_RS22610	COG3061	Opacity-associated protein A
B7485_RS22615	COG1309	transcriptional regulator
B7485_RS22655	COG1309	transcriptional regulator
B7485_RS22670	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B7485_RS22675	COG1027	Aspartate ammonia-lyase
B7485_RS22680	COG3030	protein affecting phage T7 exclusion by the F plasmid
B7485_RS22685	COG0531	amino acid
B7485_RS22720	COG1509	lysine 2,3-aminomutase activity
B7485_RS22730	COG5510	response to toxic substance
B7485_RS22735	COG5510	response to toxic substance
B7485_RS22740	COG2076	Multidrug Resistance protein
B7485_RS22745	COG3040	lipid binding
B7485_RS22750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7485_RS22765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7485_RS22770	COG1053	succinate dehydrogenase
B7485_RS22780	COG0531	amino acid
B7485_RS22795	COG1511	domain protein
B7485_RS22795	COG3264	Mechanosensitive ion channel
B7485_RS22840	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B7485_RS22845	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B7485_RS22845	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B7485_RS22850	COG0802	atpase or kinase
B7485_RS22855	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7485_RS22875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7485_RS22880	COG0330	HflC and HflK could
B7485_RS22885	COG0330	HflC and HflK could
B7485_RS22890	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
B7485_RS22905	COG0557	exoribonuclease II activity
B7485_RS22910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7485_RS22920	COG3766	membrane
B7485_RS22925	COG5463	Belongs to the UPF0441 family
B7485_RS22930	COG0754	glutathionylspermidine amidase activity
B7485_RS22935	COG1960	acyl-CoA dehydrogenase activity
B7485_RS22945	COG3650	response to hydrogen peroxide
B7485_RS22950	COG1073	alpha beta
B7485_RS23010	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B7485_RS23050	COG0732	type I restriction modification DNA specificity domain
B7485_RS23075	COG0523	cobalamin synthesis protein
B7485_RS23080	COG2879	small protein
B7485_RS23085	COG1966	Carbon starvation protein
B7485_RS23090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7485_RS23120	COG3971	2-oxopent-4-enoate hydratase activity
B7485_RS23130	COG3384	dioxygenase
B7485_RS23135	COG1012	belongs to the aldehyde dehydrogenase family
B7485_RS23140	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7485_RS23145	COG1846	Transcriptional regulator
B7485_RS23150	COG0840	transmembrane signaling receptor activity
B7485_RS23160	COG1802	Transcriptional regulator
B7485_RS23180	COG1484	DNA-dependent DNA replication
B7485_RS23195	COG2966	Psort location CytoplasmicMembrane, score
B7485_RS23210	COG2197	response regulator
B7485_RS23215	COG4114	ferric iron reductase
B7485_RS23245	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
B7485_RS23250	COG0456	acetyltransferase
B7485_RS23255	COG1011	Hydrolase
B7485_RS23265	COG2823	Periplasmic or secreted lipoprotein
B7485_RS23275	COG4667	esterase of the alpha-beta hydrolase superfamily
B7485_RS23280	COG0084	hydrolase, TatD family'
B7485_RS23285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B7485_RS23290	COG1328	CTP reductase activity
B7485_RS23325	COG3726	membrane protein affecting hemolysin expression
B7485_RS23330	COG0560	Phosphoserine phosphatase
B7485_RS23335	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B7485_RS23340	COG1056	cytidyltransferase-related domain
B7485_RS23340	COG3172	ATPase kinase involved in NAD metabolism
B7485_RS23345	COG0488	(ABC) transporter
B7485_RS23350	COG0741	lytic transglycosylase activity
B7485_RS23370	COG2207	Transcriptional regulator
B7485_RS23370	COG3708	Transcriptional regulator
B7485_RS23375	COG3045	CreA protein
B7485_RS23380	COG0745	RESPONSE REGULATOR receiver
B7485_RS23385	COG2205	protein histidine kinase activity
B7485_RS23390	COG4452	Inner membrane protein CreD
B7485_RS23395	COG0745	RESPONSE REGULATOR receiver
B7485_RS23405	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
B7485_RS23520	COG3385	transposase activity
B7485_RS23530	COG3436	PFAM IS66 Orf2 family protein
B7485_RS23650	COG3344	reverse transcriptase
B7485_RS23715	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS23815	COG2271	Major facilitator Superfamily
B7485_RS23890	COG4372	Transposase
B7485_RS24010	COG3436	PFAM IS66 Orf2 family protein
B7485_RS24045	COG3547	Transposase (IS116 IS110 IS902 family)
B7485_RS24325	COG3344	reverse transcriptase
B7485_RS24475	COG4372	Transposase
B7485_RS24480	COG3436	PFAM IS66 Orf2 family protein
B7485_RS24520	COG3436	PFAM IS66 Orf2 family protein
B7485_RS24625	COG3385	transposase activity
B7485_RS24655	COG0726	polysaccharide deacetylase
B7485_RS24660	COG0297	glycogen (starch) synthase activity
B7485_RS24665	COG2990	Protein conserved in bacteria
B7485_RS24715	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
B7485_RS24795	COG3385	transposase activity