locus-tag	class	description
BS653_RS00055	COG1783	phage Terminase large subunit
BS653_RS00085	COG1484	DNA-dependent DNA replication
BS653_RS00090	COG0305	Participates in initiation and elongation during chromosome replication
BS653_RS00140	COG3772	lysozyme
BS653_RS00280	COG0582	viral genome integration into host DNA
BS653_RS00290	COG1881	PFAM PEBP family protein
BS653_RS00295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS653_RS00310	COG2226	methyltransferase
BS653_RS00315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BS653_RS00325	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BS653_RS00335	COG0521	Mo-molybdopterin cofactor biosynthetic process
BS653_RS00345	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BS653_RS00350	COG0314	molybdopterin synthase activity
BS653_RS00355	COG0670	Belongs to the BI1 family
BS653_RS00360	COG0670	Belongs to the BI1 family
BS653_RS00365	COG0392	lysyltransferase activity
BS653_RS00375	COG3568	Endonuclease Exonuclease Phosphatase
BS653_RS00385	COG0842	Transport permease protein
BS653_RS00390	COG0842	Transport permease protein
BS653_RS00395	COG1131	(ABC) transporter
BS653_RS00405	COG1309	transcriptional regulator
BS653_RS00410	COG0513	Belongs to the DEAD box helicase family
BS653_RS00430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BS653_RS00435	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BS653_RS00445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS653_RS00460	COG3385	transposase activity
BS653_RS00485	COG1126	abc transporter atp-binding protein
BS653_RS00490	COG0765	amino acid transport
BS653_RS00495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS653_RS00515	COG5006	permease, DMT superfamily
BS653_RS00520	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BS653_RS00525	COG2194	sulfuric ester hydrolase activity
BS653_RS00540	COG2194	sulfuric ester hydrolase activity
BS653_RS00550	COG1321	iron dependent repressor
BS653_RS00555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS653_RS00560	COG1376	ErfK ybiS ycfS ynhG family protein
BS653_RS00565	COG0488	(ABC) transporter
BS653_RS00575	COG0561	phosphatase activity
BS653_RS00580	COG1882	Formate acetyltransferase
BS653_RS00585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BS653_RS00590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BS653_RS00595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS653_RS00600	COG0303	'Molybdopterin
BS653_RS00605	COG1446	asparaginase
BS653_RS00630	COG2200	EAL domain
BS653_RS00635	COG2200	EAL domain
BS653_RS00640	COG2199	diguanylate cyclase activity
BS653_RS00655	COG2133	pyrroloquinoline quinone binding
BS653_RS00660	COG2133	pyrroloquinoline quinone binding
BS653_RS00665	COG0625	glutathione transferase activity
BS653_RS00670	COG1686	Belongs to the peptidase S11 family
BS653_RS00680	COG1686	Belongs to the peptidase S11 family
BS653_RS00685	COG1349	DNA-binding transcription factor activity
BS653_RS00690	COG0671	phosphoesterase, PA-phosphatase related
BS653_RS00695	COG2814	Major facilitator Superfamily
BS653_RS00705	COG0561	phosphatase activity
BS653_RS00710	COG0738	Major facilitator superfamily
BS653_RS00715	COG3226	Transcriptional regulator
BS653_RS00730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BS653_RS00740	COG0778	Nitroreductase
BS653_RS00760	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BS653_RS00765	COG3842	ATPase activity
BS653_RS00770	COG1176	ABC-type spermidine putrescine transport system, permease component I
BS653_RS00775	COG1177	transmembrane transport
BS653_RS00790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS653_RS00795	COG4160	amino acid transport
BS653_RS00800	COG4215	(ABC) transporter
BS653_RS00805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS653_RS00810	COG1126	abc transporter atp-binding protein
BS653_RS00840	COG3023	N-Acetylmuramoyl-L-alanine amidase
BS653_RS00845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS653_RS00850	COG0702	epimerase
BS653_RS00855	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BS653_RS00860	COG0028	Belongs to the TPP enzyme family
BS653_RS00865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS653_RS00875	COG2431	L-lysine efflux transmembrane transporter activity
BS653_RS00900	COG3593	DNA synthesis involved in DNA repair
BS653_RS00905	COG2990	Protein conserved in bacteria
BS653_RS00910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS653_RS00920	COG1278	Cold shock
BS653_RS00930	COG0542	response to heat
BS653_RS00955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BS653_RS00960	COG4988	ABC transporter
BS653_RS00965	COG0492	ferredoxin-NADP+ reductase activity
BS653_RS00975	COG1522	sequence-specific DNA binding
BS653_RS00990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BS653_RS01000	COG0243	molybdopterin cofactor binding
BS653_RS01005	COG0243	molybdopterin cofactor binding
BS653_RS01010	COG0437	4 iron, 4 sulfur cluster binding
BS653_RS01015	COG3302	dmso reductase anchor subunit
BS653_RS01020	COG1335	isochorismatase
BS653_RS01040	COG3436	PFAM IS66 Orf2 family protein
BS653_RS01045	COG4372	Transposase
BS653_RS01070	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BS653_RS01105	COG1396	sequence-specific DNA binding
BS653_RS01135	COG3646	Phage regulatory protein
BS653_RS01150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS653_RS01185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS653_RS01200	COG2828	Protein conserved in bacteria
BS653_RS01205	COG0471	metal ion transport
BS653_RS01210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BS653_RS01215	COG4677	pectinesterase activity
BS653_RS01220	COG0582	viral genome integration into host DNA
BS653_RS01235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BS653_RS01240	COG1882	Formate acetyltransferase
BS653_RS01245	COG2116	formate transmembrane transporter activity
BS653_RS01250	COG1944	ATP diphosphatase activity
BS653_RS01270	COG3385	transposase activity
BS653_RS01275	COG0501	Belongs to the peptidase M48B family
BS653_RS01285	COG0539	negative regulation of cytoplasmic translation
BS653_RS01315	COG3214	Protein conserved in bacteria
BS653_RS01330	COG3173	Aminoglycoside phosphotransferase
BS653_RS01335	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BS653_RS01345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BS653_RS01355	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BS653_RS01370	COG2989	Protein conserved in bacteria
BS653_RS01380	COG3108	Peptidase M15
BS653_RS01385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS653_RS01395	COG1448	Aminotransferase
BS653_RS01415	COG0308	aminopeptidase N
BS653_RS01425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS653_RS01435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS653_RS01445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS653_RS01450	COG0431	NADPH-dependent FMN reductase
BS653_RS01465	COG3539	Fimbrial protein
BS653_RS01475	COG3188	usher protein
BS653_RS01480	COG3539	Fimbrial protein
BS653_RS01490	COG3539	Fimbrial protein
BS653_RS01495	COG3121	Chaperone
BS653_RS01510	COG0633	Ferredoxin
BS653_RS01510	COG3217	Mosc domain protein beta barrel domain protein
BS653_RS01520	COG0488	(ABC) transporter
BS653_RS01525	COG2995	paraquat-inducible protein a
BS653_RS01530	COG3008	intermembrane lipid transfer
BS653_RS01530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BS653_RS01535	COG3009	Protein conserved in bacteria
BS653_RS01540	COG3130	regulation of translation
BS653_RS01550	COG1067	ATP-dependent peptidase activity
BS653_RS01575	COG3070	regulator of competence-specific genes
BS653_RS01585	COG1289	transmembrane transporter activity
BS653_RS01590	COG3304	Inner membrane component domain
BS653_RS01595	COG0210	DNA helicase
BS653_RS01610	COG1832	CoA-binding protein
BS653_RS01630	COG2920	part of a sulfur-relay system
BS653_RS01635	COG0670	Belongs to the BI1 family
BS653_RS01645	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BS653_RS01650	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BS653_RS01655	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BS653_RS01660	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BS653_RS01665	COG1999	signal sequence binding
BS653_RS01670	COG1773	rubredoxin
BS653_RS01675	COG1271	oxidase subunit
BS653_RS01680	COG1294	oxidase, subunit
BS653_RS01695	COG0489	protein tyrosine kinase activity
BS653_RS01695	COG3206	protein involved in exopolysaccharide biosynthesis
BS653_RS01700	COG3206	protein involved in exopolysaccharide biosynthesis
BS653_RS01700	COG0489	protein tyrosine kinase activity
BS653_RS01705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS653_RS01710	COG1596	polysaccharide export
BS653_RS01715	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BS653_RS01735	COG1278	Cold shock
BS653_RS01750	COG1278	Cold shock
BS653_RS01770	COG0348	domain, Protein
BS653_RS01775	COG0784	Response regulator, receiver
BS653_RS01775	COG2198	Histidine kinase
BS653_RS01775	COG2205	protein histidine kinase activity
BS653_RS01780	COG2198	Histidine kinase
BS653_RS01780	COG2205	protein histidine kinase activity
BS653_RS01780	COG0784	Response regulator, receiver
BS653_RS01785	COG1879	ABC-type sugar transport system periplasmic component
BS653_RS01790	COG0745	RESPONSE REGULATOR receiver
BS653_RS01795	COG3005	denitrification pathway
BS653_RS01850	COG3729	General stress protein
BS653_RS01855	COG2233	PERMEase
BS653_RS01890	COG1309	transcriptional regulator
BS653_RS01920	COG2822	iron ion transport
BS653_RS01930	COG1702	phosphate starvation-inducible protein PhoH
BS653_RS01950	COG0582	viral genome integration into host DNA
BS653_RS02020	COG1309	transcriptional regulator
BS653_RS02040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BS653_RS02060	COG0438	transferase activity, transferring glycosyl groups
BS653_RS02155	COG1662	PFAM IS1 transposase
BS653_RS02155	COG3677	Transposase
BS653_RS02160	COG1662	PFAM IS1 transposase
BS653_RS02195	COG2003	Belongs to the UPF0758 family
BS653_RS02260	COG3381	protein complex oligomerization
BS653_RS02285	COG2197	response regulator
BS653_RS02345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS653_RS02370	COG2943	transferase activity, transferring hexosyl groups
BS653_RS02425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS653_RS02435	COG1560	Kdo2-lipid A biosynthetic process
BS653_RS02450	COG3038	cytochrome b561
BS653_RS02485	COG2999	glutathione oxidoreductase activity
BS653_RS02495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS653_RS02505	COG0673	inositol 2-dehydrogenase activity
BS653_RS02510	COG0728	peptidoglycan biosynthetic process
BS653_RS02515	COG3418	PFAM FlgN family protein
BS653_RS02520	COG2747	anti-sigma28 factor FlgM
BS653_RS02525	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BS653_RS02530	COG1815	bacterial-type flagellum-dependent cell motility
BS653_RS02540	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BS653_RS02545	COG1749	Flagellar hook protein flgE
BS653_RS02555	COG4786	Flagellar basal body rod
BS653_RS02570	COG3951	Flagellar rod assembly protein muramidase FlgJ
BS653_RS02570	COG1705	Flagellar rod assembly protein muramidase FlgJ
BS653_RS02585	COG1530	ribonuclease E activity
BS653_RS02595	COG0564	pseudouridine synthase activity
BS653_RS02600	COG0424	maF-like protein
BS653_RS02605	COG1399	metal-binding, possibly nucleic acid-binding protein
BS653_RS02625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BS653_RS02630	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS02640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS653_RS02645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS653_RS02650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS653_RS02660	COG0470	DNA polymerase III
BS653_RS02665	COG0084	hydrolase, TatD family'
BS653_RS02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS653_RS02670	COG1263	PTS System
BS653_RS02680	COG0537	adenosine 5'-monophosphoramidase activity
BS653_RS02685	COG5633	Lipoprotein
BS653_RS02690	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BS653_RS02710	COG1252	NADH dehydrogenase
BS653_RS02720	COG3134	Outer membrane lipoprotein
BS653_RS02725	COG1309	transcriptional regulator
BS653_RS02735	COG1376	ErfK ybiS ycfS ynhG family protein
BS653_RS02735	COG1388	LysM domain
BS653_RS02740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BS653_RS02745	COG4763	Acyl-transferase
BS653_RS02750	COG4591	ABC-type transport system involved in lipoprotein release permease component
BS653_RS02760	COG4591	ABC-type transport system involved in lipoprotein release permease component
BS653_RS02775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BS653_RS02780	COG1177	transmembrane transport
BS653_RS02790	COG3842	ATPase activity
BS653_RS02805	COG2850	peptidyl-arginine hydroxylation
BS653_RS02915	COG1802	Transcriptional regulator
BS653_RS02915	COG4626	Terminase
BS653_RS02935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BS653_RS02960	COG0538	isocitrate dehydrogenase activity
BS653_RS02970	COG2200	EAL domain
BS653_RS03030	COG2894	cell division
BS653_RS03080	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS653_RS03095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS653_RS03100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS653_RS03120	COG2719	SpoVR family
BS653_RS03130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS653_RS03145	COG1619	proteins homologs of microcin C7 resistance protein MccF
BS653_RS03160	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BS653_RS03175	COG0157	Belongs to the NadC ModD family
BS653_RS03180	COG0500	methyltransferase
BS653_RS03185	COG1120	ATPase activity
BS653_RS03190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS653_RS03195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS653_RS03225	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BS653_RS03225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS653_RS03225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS03230	COG1461	Dihydroxyacetone kinase
BS653_RS03235	COG2376	Dihydroxyacetone kinase
BS653_RS03240	COG3284	Transcriptional regulator
BS653_RS03245	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS03260	COG0012	GTP binding
BS653_RS03275	COG0659	secondary active sulfate transmembrane transporter activity
BS653_RS03280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BS653_RS03305	COG2890	protein-(glutamine-N5) methyltransferase activity
BS653_RS03310	COG3094	Invasion gene expression up-regulator, SirB
BS653_RS03315	COG2912	Transglutaminase-like superfamily
BS653_RS03335	COG0387	Pfam Sodium calcium exchanger
BS653_RS03340	COG4572	Cation transport regulator
BS653_RS03345	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BS653_RS03350	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BS653_RS03355	COG4932	domain protein
BS653_RS03360	COG2197	response regulator
BS653_RS03365	COG3850	Histidine kinase
BS653_RS03375	COG2223	nitrite transmembrane transporter activity
BS653_RS03380	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BS653_RS03385	COG1140	nitrate reductase beta subunit
BS653_RS03390	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BS653_RS03395	COG2181	nitrate reductase activity
BS653_RS03410	COG0788	formyltetrahydrofolate deformylase activity
BS653_RS03420	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS653_RS03425	COG0745	RESPONSE REGULATOR receiver
BS653_RS03430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS653_RS03440	COG1435	thymidine kinase activity
BS653_RS03445	COG3385	transposase activity
BS653_RS03450	COG1012	belongs to the aldehyde dehydrogenase family
BS653_RS03450	COG1454	alcohol dehydrogenase
BS653_RS03455	COG2095	MarC family integral membrane protein
BS653_RS03465	COG4166	transmembrane transport
BS653_RS03470	COG0601	transmembrane transport
BS653_RS03475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS653_RS03480	COG0444	Belongs to the ABC transporter superfamily
BS653_RS03485	COG4608	Belongs to the ABC transporter superfamily
BS653_RS03505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BS653_RS03515	COG2350	Protein conserved in bacteria
BS653_RS03520	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BS653_RS03525	COG1607	acyl-coa hydrolase
BS653_RS03545	COG3047	cAMP biosynthetic process
BS653_RS03550	COG3685	Protein conserved in bacteria
BS653_RS03555	COG3685	Protein conserved in bacteria
BS653_RS03560	COG3729	General stress protein
BS653_RS03575	COG0134	indole-3-glycerol-phosphate synthase activity
BS653_RS03575	COG0135	phosphoribosylanthranilate isomerase activity
BS653_RS03580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BS653_RS03580	COG0512	Glutamine amidotransferase of anthranilate synthase
BS653_RS03585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BS653_RS03595	COG0613	PHP domain protein
BS653_RS03600	COG0009	L-threonylcarbamoyladenylate synthase
BS653_RS03610	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BS653_RS03615	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS03620	COG0616	signal peptide processing
BS653_RS03635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS653_RS03645	COG0583	DNA-binding transcription factor activity
BS653_RS03665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BS653_RS03675	COG0671	phosphoesterase, PA-phosphatase related
BS653_RS03680	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BS653_RS03685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BS653_RS03695	COG0023	Translation Initiation Factor
BS653_RS03705	COG1349	DNA-binding transcription factor activity
BS653_RS03735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS653_RS03735	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS653_RS03740	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BS653_RS03745	COG2852	Protein conserved in bacteria
BS653_RS03750	COG4172	Belongs to the ABC transporter superfamily
BS653_RS03755	COG4172	Belongs to the ABC transporter superfamily
BS653_RS03760	COG4171	peptide transport system, permease
BS653_RS03765	COG4168	peptide transport system, permease
BS653_RS03770	COG4166	transmembrane transport
BS653_RS03785	COG0531	amino acid
BS653_RS03790	COG0174	glutamine synthetase
BS653_RS03800	COG1917	Cupin 2, conserved barrel domain protein
BS653_RS03800	COG1396	sequence-specific DNA binding
BS653_RS03805	COG1012	belongs to the aldehyde dehydrogenase family
BS653_RS03810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS653_RS03815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BS653_RS03820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BS653_RS03825	COG1842	Phage shock protein A
BS653_RS03835	COG1983	PspC domain protein
BS653_RS03845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS653_RS03850	COG0366	Alpha amylase catalytic
BS653_RS03860	COG0366	Alpha amylase catalytic
BS653_RS03870	COG1175	transmembrane transport
BS653_RS03875	COG0395	ABC-type sugar transport system, permease component
BS653_RS03880	COG1063	alcohol dehydrogenase
BS653_RS03895	COG1554	hydrolase, family 65, central catalytic
BS653_RS03900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS653_RS03920	COG1609	Transcriptional regulator
BS653_RS03925	COG3106	COG3106 Predicted ATPase
BS653_RS03935	COG3283	Transcriptional regulator of aromatic amino acids metabolism
BS653_RS03940	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BS653_RS03945	COG4948	Mandelate Racemase Muconate Lactonizing
BS653_RS03950	COG2866	Carboxypeptidase
BS653_RS03955	COG0702	epimerase
BS653_RS03960	COG1073	alpha beta
BS653_RS03965	COG3547	Transposase (IS116 IS110 IS902 family)
BS653_RS03975	COG1073	alpha beta
BS653_RS03980	COG0583	DNA-binding transcription factor activity
BS653_RS03990	COG3756	Protein conserved in bacteria
BS653_RS04000	COG3756	Protein conserved in bacteria
BS653_RS04005	COG1484	DNA-dependent DNA replication
BS653_RS04115	COG4974	Belongs to the 'phage' integrase family
BS653_RS04160	COG5301	cellulose 1,4-beta-cellobiosidase activity
BS653_RS04170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS653_RS04175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS653_RS04180	COG1121	(ABC) transporter
BS653_RS04190	COG0582	viral genome integration into host DNA
BS653_RS04200	COG0582	viral genome integration into host DNA
BS653_RS04230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS653_RS04295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BS653_RS04305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BS653_RS04330	COG2995	paraquat-inducible protein a
BS653_RS04335	COG1956	GAF domain-containing protein
BS653_RS04345	COG0793	Belongs to the peptidase S41A family
BS653_RS04355	COG2814	Major facilitator Superfamily
BS653_RS04360	COG1414	Transcriptional regulator
BS653_RS04395	COG2226	methyltransferase
BS653_RS04420	COG3716	PTS system mannose fructose sorbose family IID component
BS653_RS04425	COG3715	PTS system
BS653_RS04430	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS653_RS04430	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS04445	COG1253	flavin adenine dinucleotide binding
BS653_RS04450	COG2200	EAL domain
BS653_RS04455	COG1760	l-serine dehydratase
BS653_RS04465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BS653_RS04480	COG0251	oxidation-reduction process
BS653_RS04485	COG1199	ATP-dependent helicase activity
BS653_RS04490	COG1214	PFAM Peptidase M22, glycoprotease
BS653_RS04495	COG3065	identical protein binding
BS653_RS04500	COG0318	PFAM AMP-dependent synthetase and ligase
BS653_RS04505	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BS653_RS04510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS653_RS04515	COG4638	Rieske (2fe-2S)
BS653_RS04555	COG2199	diguanylate cyclase activity
BS653_RS04555	COG2203	Gaf domain
BS653_RS04560	COG3042	response to heat
BS653_RS04565	COG3189	MarR family transcriptional regulator
BS653_RS04590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BS653_RS04595	COG2199	diguanylate cyclase activity
BS653_RS04605	COG2766	serine protein kinase
BS653_RS04610	COG3713	MltA-interacting MipA family protein
BS653_RS04615	COG0656	L-ascorbic acid biosynthetic process
BS653_RS04620	COG0676	glucose-6-phosphate 1-epimerase activity
BS653_RS04625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS653_RS04635	COG3139	Protein of unknown function (DUF1315)
BS653_RS04640	COG1063	alcohol dehydrogenase
BS653_RS04645	COG2271	Major facilitator Superfamily
BS653_RS04655	COG0191	fructose-bisphosphate aldolase activity
BS653_RS04660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS653_RS04665	COG0667	Aldo Keto reductase
BS653_RS04670	COG1349	DNA-binding transcription factor activity
BS653_RS04675	COG2814	Major facilitator Superfamily
BS653_RS04680	COG1335	isochorismatase
BS653_RS04685	COG0252	asparaginase activity
BS653_RS04690	COG0616	signal peptide processing
BS653_RS04700	COG0778	Nitroreductase
BS653_RS04715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS653_RS04730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS653_RS04740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS653_RS04750	COG0494	nUDIX hydrolase
BS653_RS04755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BS653_RS04765	COG4136	ATPase activity
BS653_RS04785	COG4134	Bacterial extracellular solute-binding protein
BS653_RS04790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS653_RS04795	COG0398	Pfam SNARE associated Golgi protein
BS653_RS04805	COG0398	Pfam SNARE associated Golgi protein
BS653_RS04810	COG0708	Exodeoxyribonuclease III
BS653_RS04845	COG3678	ATP-independent chaperone mediated protein folding
BS653_RS04865	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BS653_RS04875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS653_RS04885	COG1447	Phosphotransferase system cellobiose-specific component IIA
BS653_RS04905	COG1988	membrane-bound metal-dependent
BS653_RS04910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS653_RS04920	COG3001	Fructosamine kinase
BS653_RS04930	COG1105	Belongs to the carbohydrate kinase PfkB family
BS653_RS04935	COG3137	Salt-induced outer membrane protein
BS653_RS05005	COG0386	Belongs to the glutathione peroxidase family
BS653_RS05015	COG0791	NLP P60 protein
BS653_RS05020	COG2200	EAL domain
BS653_RS05030	COG4256	Hemin uptake protein
BS653_RS05050	COG0574	Belongs to the PEP-utilizing enzyme family
BS653_RS05050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS653_RS05055	COG0318	PFAM AMP-dependent synthetase and ligase
BS653_RS05060	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BS653_RS05065	COG0644	oxidoreductase
BS653_RS05070	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BS653_RS05075	COG2086	electron transfer activity
BS653_RS05085	COG2207	Transcriptional regulator
BS653_RS05085	COG1917	Cupin 2, conserved barrel domain protein
BS653_RS05095	COG3119	arylsulfatase activity
BS653_RS05115	COG3539	Fimbrial protein
BS653_RS05170	COG0484	heat shock protein binding
BS653_RS05175	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BS653_RS05180	COG1403	HNH endonuclease
BS653_RS05200	COG2026	Addiction module toxin, RelE StbE family
BS653_RS05205	COG3077	Addiction module antitoxin, RelB DinJ family
BS653_RS05220	COG0477	Major facilitator Superfamily
BS653_RS05225	COG0246	Mannitol dehydrogenase
BS653_RS05235	COG1802	Transcriptional regulator
BS653_RS05250	COG0339	signal peptide processing
BS653_RS05260	COG1546	Belongs to the CinA family
BS653_RS05265	COG3111	PFAM Bacterial OB fold (BOF) protein
BS653_RS05280	COG2814	Major facilitator Superfamily
BS653_RS05285	COG0697	spore germination
BS653_RS05295	COG4977	sequence-specific DNA binding
BS653_RS05300	COG1846	Transcriptional regulator
BS653_RS05320	COG1012	belongs to the aldehyde dehydrogenase family
BS653_RS05340	COG2199	diguanylate cyclase activity
BS653_RS05370	COG3781	membrane
BS653_RS05440	COG4948	Mandelate Racemase Muconate Lactonizing
BS653_RS05480	COG0243	molybdopterin cofactor binding
BS653_RS05545	COG0243	molybdopterin cofactor binding
BS653_RS05555	COG0437	4 iron, 4 sulfur cluster binding
BS653_RS05560	COG3302	dmso reductase anchor subunit
BS653_RS05565	COG3381	protein complex oligomerization
BS653_RS05580	COG1940	carbohydrate kinase activity
BS653_RS05585	COG0583	DNA-binding transcription factor activity
BS653_RS05610	COG3591	Belongs to the peptidase S1B family
BS653_RS05630	COG0628	permease
BS653_RS05635	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BS653_RS05640	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BS653_RS05655	COG0531	amino acid
BS653_RS05665	COG3136	membrane protein required for alginate biosynthesis
BS653_RS05670	COG0745	RESPONSE REGULATOR receiver
BS653_RS05675	COG1823	symporter activity
BS653_RS05685	COG2205	protein histidine kinase activity
BS653_RS05700	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BS653_RS05700	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BS653_RS05710	COG5339	Protein conserved in bacteria
BS653_RS05725	COG3250	beta-galactosidase activity
BS653_RS05730	COG1309	transcriptional regulator
BS653_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS05745	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS05750	COG1609	Transcriptional regulator
BS653_RS05755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS653_RS05755	COG1263	PTS System
BS653_RS05760	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BS653_RS05770	COG0673	inositol 2-dehydrogenase activity
BS653_RS05815	COG4659	FMN binding
BS653_RS05825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BS653_RS05835	COG3104	oligopeptide transport
BS653_RS05840	COG0625	glutathione transferase activity
BS653_RS05860	COG3895	Periplasmic Protein
BS653_RS05870	COG3895	Periplasmic Protein
BS653_RS05880	COG3133	Outer membrane lipoprotein
BS653_RS05895	COG1566	PFAM secretion protein HlyD family protein
BS653_RS05905	COG2032	superoxide dismutase activity
BS653_RS05910	COG4989	oxidoreductase activity
BS653_RS05915	COG3313	Fe-S protein
BS653_RS05920	COG1309	transcriptional regulator
BS653_RS05925	COG1902	pentaerythritol trinitrate reductase activity
BS653_RS05930	COG0346	lactoylglutathione lyase activity
BS653_RS05945	COG0675	Transposase, IS605 OrfB family
BS653_RS05955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BS653_RS05960	COG0791	NLP P60 protein
BS653_RS05965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS653_RS05970	COG2814	Major facilitator Superfamily
BS653_RS05990	COG0583	DNA-binding transcription factor activity
BS653_RS05995	COG2814	Major facilitator Superfamily
BS653_RS06000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BS653_RS06005	COG0307	riboflavin synthase, alpha
BS653_RS06015	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS06045	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BS653_RS06050	COG0437	4 iron, 4 sulfur cluster binding
BS653_RS06065	COG2414	aldehyde ferredoxin oxidoreductase
BS653_RS06070	COG0437	4 iron, 4 sulfur cluster binding
BS653_RS06085	COG0469	pyruvate kinase activity
BS653_RS06090	COG4238	major outer membrane lipoprotein
BS653_RS06095	COG1376	ErfK ybiS ycfS ynhG family protein
BS653_RS06110	COG0719	Fe-S assembly protein
BS653_RS06115	COG0396	ATPase activity
BS653_RS06120	COG0719	Fe-S assembly protein
BS653_RS06125	COG0316	Belongs to the HesB IscA family
BS653_RS06135	COG2050	protein possibly involved in aromatic compounds catabolism
BS653_RS06140	COG0247	lactate metabolic process
BS653_RS06140	COG0277	FAD linked oxidase domain protein
BS653_RS06150	COG0628	permease
BS653_RS06165	COG0738	Major facilitator superfamily
BS653_RS06195	COG3119	arylsulfatase activity
BS653_RS06200	COG0641	radical SAM
BS653_RS06210	COG4771	TonB-dependent receptor
BS653_RS06215	COG0612	Peptidase, M16
BS653_RS06225	COG0612	Peptidase, M16
BS653_RS06240	COG0076	glutamate decarboxylase activity
BS653_RS06245	COG0531	amino acid
BS653_RS06250	COG1649	PFAM Uncharacterised BCR, COG1649
BS653_RS06260	COG2200	EAL domain
BS653_RS06260	COG2199	diguanylate cyclase activity
BS653_RS06260	COG2202	Pas domain
BS653_RS06265	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BS653_RS06270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS653_RS06275	COG0444	Belongs to the ABC transporter superfamily
BS653_RS06285	COG1764	response to oxidative stress
BS653_RS06300	COG1064	alcohol dehydrogenase
BS653_RS06305	COG3093	addiction module antidote protein HigA
BS653_RS06310	COG2864	formate dehydrogenase
BS653_RS06315	COG0437	4 iron, 4 sulfur cluster binding
BS653_RS06325	COG0697	spore germination
BS653_RS06340	COG4886	Leucine-rich repeat (LRR) protein
BS653_RS06345	COG4886	Leucine-rich repeat (LRR) protein
BS653_RS06355	COG2223	nitrite transmembrane transporter activity
BS653_RS06365	COG1140	nitrate reductase beta subunit
BS653_RS06380	COG1802	Transcriptional regulator
BS653_RS06385	COG2130	NADP-dependent
BS653_RS06395	COG1247	-acetyltransferase
BS653_RS06400	COG3238	Protein conserved in bacteria
BS653_RS06435	COG1177	transmembrane transport
BS653_RS06440	COG1176	ABC-type spermidine putrescine transport system, permease component I
BS653_RS06480	COG0500	methyltransferase
BS653_RS06485	COG1275	C4-dicarboxylate transporter malic acid transport protein
BS653_RS06490	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BS653_RS06495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS653_RS06500	COG2841	Protein conserved in bacteria
BS653_RS06520	COG5383	Protein conserved in bacteria
BS653_RS06525	COG0583	DNA-binding transcription factor activity
BS653_RS06530	COG0840	transmembrane signaling receptor activity
BS653_RS06550	COG2801	Transposase and inactivated derivatives
BS653_RS06565	COG3038	cytochrome b561
BS653_RS06575	COG1012	belongs to the aldehyde dehydrogenase family
BS653_RS06580	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BS653_RS06600	COG1643	Atp-dependent helicase
BS653_RS06610	COG0671	phosphoesterase, PA-phosphatase related
BS653_RS06610	COG2453	phosphatase
BS653_RS06620	COG0671	phosphoesterase, PA-phosphatase related
BS653_RS06620	COG2453	phosphatase
BS653_RS06625	COG2267	carboxylic ester hydrolase activity
BS653_RS06635	COG2267	carboxylic ester hydrolase activity
BS653_RS06645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BS653_RS06660	COG3187	Heat shock protein
BS653_RS06665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS653_RS06670	COG2911	Protein conserved in bacteria
BS653_RS06680	COG3784	Protein of unknown function (DUF1318)
BS653_RS06685	COG2207	Transcriptional regulator
BS653_RS06695	COG3042	response to heat
BS653_RS06700	COG1013	pyruvate-flavodoxin oxidoreductase activity
BS653_RS06700	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BS653_RS06700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS653_RS06700	COG0674	pyruvate-flavodoxin oxidoreductase activity
BS653_RS06710	COG0589	response to stress
BS653_RS06720	COG0513	Belongs to the DEAD box helicase family
BS653_RS06770	COG2207	Transcriptional regulator
BS653_RS06780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BS653_RS06785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS653_RS06790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS653_RS06795	COG0589	response to stress
BS653_RS06825	COG0668	transmembrane transport
BS653_RS06830	COG4166	transmembrane transport
BS653_RS06835	COG0583	DNA-binding transcription factor activity
BS653_RS06880	COG2372	response to copper ion
BS653_RS06895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS653_RS06900	COG1770	oligopeptidase
BS653_RS06910	COG2979	Protein of unknown function (DUF533)
BS653_RS06930	COG0800	Aldolase
BS653_RS06935	COG0129	dihydroxy-acid dehydratase activity
BS653_RS06940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BS653_RS06945	COG1737	Transcriptional regulator
BS653_RS06950	COG0469	pyruvate kinase activity
BS653_RS06960	COG0739	heme binding
BS653_RS06965	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BS653_RS06975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS653_RS07005	COG0217	transcriptional regulatory protein
BS653_RS07010	COG0494	nUDIX hydrolase
BS653_RS07020	COG1335	isochorismatase
BS653_RS07025	COG3547	Transposase (IS116 IS110 IS902 family)
BS653_RS07030	COG1335	isochorismatase
BS653_RS07140	COG3547	Transposase (IS116 IS110 IS902 family)
BS653_RS07175	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BS653_RS07240	COG1801	Protein of unknown function DUF72
BS653_RS07245	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BS653_RS07260	COG0243	molybdopterin cofactor binding
BS653_RS07265	COG3005	denitrification pathway
BS653_RS07275	COG3102	Protein conserved in bacteria
BS653_RS07290	COG3755	Protein conserved in bacteria
BS653_RS07310	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS653_RS07315	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BS653_RS07350	COG0745	RESPONSE REGULATOR receiver
BS653_RS07360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BS653_RS07365	COG0840	transmembrane signaling receptor activity
BS653_RS07370	COG0840	transmembrane signaling receptor activity
BS653_RS07375	COG0835	chemotaxis
BS653_RS07380	COG0643	Histidine kinase
BS653_RS07380	COG2198	Histidine kinase
BS653_RS07385	COG1360	Flagellar Motor Protein
BS653_RS07390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS653_RS07415	COG1877	trehalose-phosphatase activity
BS653_RS07420	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS653_RS07440	COG1528	Iron-storage protein
BS653_RS07460	COG1528	Iron-storage protein
BS653_RS07470	COG0814	amino acid
BS653_RS07475	COG3012	SEC-C Motif Domain Protein
BS653_RS07475	COG3318	Belongs to the UPF0149 family
BS653_RS07505	COG2197	response regulator
BS653_RS07515	COG2197	response regulator
BS653_RS07520	COG1126	abc transporter atp-binding protein
BS653_RS07525	COG0765	amino acid transport
BS653_RS07535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS653_RS07560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BS653_RS07565	COG1516	flagellar protein fliS
BS653_RS07575	COG0366	Alpha amylase catalytic
BS653_RS07590	COG2391	methyltransferase activity
BS653_RS07595	COG0425	Belongs to the sulfur carrier protein TusA family
BS653_RS07630	COG1881	PFAM PEBP family protein
BS653_RS07635	COG2076	Multidrug Resistance protein
BS653_RS07655	COG1766	The M ring may be actively involved in energy transduction
BS653_RS07665	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS653_RS07670	COG1317	bacterial-type flagellum organization
BS653_RS07675	COG1157	protein secretion by the type III secretion system
BS653_RS07680	COG2882	bacterial-type flagellum organization
BS653_RS07685	COG3144	bacterial-type flagellum assembly
BS653_RS07690	COG1580	Controls the rotational direction of flagella during chemotaxis
BS653_RS07695	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS653_RS07700	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS653_RS07705	COG3190	flagellar
BS653_RS07710	COG1338	Plays a role in the flagellum-specific transport system
BS653_RS07715	COG1987	bacterial-type flagellum assembly
BS653_RS07720	COG1684	flagellar biosynthetic protein fliR
BS653_RS07725	COG2197	response regulator
BS653_RS07765	COG5475	Uncharacterized small protein (DUF2158)
BS653_RS07770	COG2354	Protein conserved in bacteria
BS653_RS07775	COG0697	spore germination
BS653_RS07780	COG3727	T/G mismatch-specific endonuclease activity
BS653_RS07785	COG0270	DNA (cytosine-5-)-methyltransferase activity
BS653_RS07805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BS653_RS07815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BS653_RS07840	COG2205	protein histidine kinase activity
BS653_RS07845	COG0745	RESPONSE REGULATOR receiver
BS653_RS07850	COG2351	hydroxyisourate hydrolase activity
BS653_RS07865	COG3443	Belongs to the bacterial solute-binding protein 9 family
BS653_RS07885	COG0500	methyltransferase
BS653_RS07935	COG4386	tail sheath protein
BS653_RS07960	COG3436	PFAM IS66 Orf2 family protein
BS653_RS08005	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BS653_RS08010	COG1403	HNH endonuclease
BS653_RS08085	COG0477	Major facilitator Superfamily
BS653_RS08090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BS653_RS08125	COG0583	DNA-binding transcription factor activity
BS653_RS08130	COG0583	DNA-binding transcription factor activity
BS653_RS08140	COG1376	ErfK ybiS ycfS ynhG family protein
BS653_RS08155	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BS653_RS08180	COG3436	PFAM IS66 Orf2 family protein
BS653_RS08195	COG0582	viral genome integration into host DNA
BS653_RS08200	COG2925	Exonuclease
BS653_RS08205	COG0425	Belongs to the sulfur carrier protein TusA family
BS653_RS08210	COG2391	methyltransferase activity
BS653_RS08215	COG0531	amino acid
BS653_RS08220	COG0583	DNA-binding transcription factor activity
BS653_RS08225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS653_RS08230	COG4115	mRNA cleavage
BS653_RS08380	COG0438	transferase activity, transferring glycosyl groups
BS653_RS08385	COG2327	Polysaccharide pyruvyl transferase
BS653_RS08390	COG2244	polysaccharide biosynthetic process
BS653_RS08395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BS653_RS08400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS653_RS08405	COG0662	Cupin 2, conserved barrel domain protein
BS653_RS08405	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BS653_RS08410	COG0297	glycogen (starch) synthase activity
BS653_RS08415	COG1051	belongs to the nudix hydrolase family
BS653_RS08420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS653_RS08425	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BS653_RS08430	COG0110	maltose O-acetyltransferase activity
BS653_RS08435	COG1216	Glycosyl transferase, family 2
BS653_RS08450	COG0438	transferase activity, transferring glycosyl groups
BS653_RS08455	COG1045	serine acetyltransferase
BS653_RS08460	COG0463	Glycosyl transferase, family 2
BS653_RS08465	COG0463	Glycosyl transferase, family 2
BS653_RS08470	COG0489	protein tyrosine kinase activity
BS653_RS08470	COG3206	protein involved in exopolysaccharide biosynthesis
BS653_RS08475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS653_RS08480	COG1596	polysaccharide export
BS653_RS08490	COG2982	Protein involved in outer membrane biogenesis
BS653_RS08500	COG0572	uridine kinase
BS653_RS08505	COG5001	Diguanylate cyclase
BS653_RS08505	COG5002	protein histidine kinase activity
BS653_RS08505	COG3447	MASE1 domain protein
BS653_RS08530	COG2205	protein histidine kinase activity
BS653_RS08535	COG0745	RESPONSE REGULATOR receiver
BS653_RS08545	COG0826	peptidase U32
BS653_RS08570	COG1063	alcohol dehydrogenase
BS653_RS08580	COG3775	system Galactitol-specific IIC component
BS653_RS08585	COG3414	Phosphotransferase system galactitol-specific IIB component
BS653_RS08590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS08605	COG1830	Aldolase
BS653_RS08615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS653_RS08620	COG2188	Transcriptional regulator
BS653_RS08625	COG3757	hydrolase, family 25
BS653_RS08630	COG0351	phosphomethylpyrimidine kinase
BS653_RS08655	COG5455	response to cobalt ion
BS653_RS08665	COG3188	usher protein
BS653_RS08670	COG3121	Chaperone
BS653_RS08675	COG3539	Fimbrial protein
BS653_RS08695	COG0489	protein tyrosine kinase activity
BS653_RS08740	COG0714	Associated with various cellular activities
BS653_RS08745	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BS653_RS08750	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BS653_RS08755	COG4715	Zinc finger, swim domain protein
BS653_RS08770	COG4808	Protein conserved in bacteria
BS653_RS08775	COG4807	Protein conserved in bacteria
BS653_RS08785	COG4807	Protein conserved in bacteria
BS653_RS08795	COG3275	phosphorelay sensor kinase activity
BS653_RS08815	COG0500	methyltransferase
BS653_RS08835	COG5301	cellulose 1,4-beta-cellobiosidase activity
BS653_RS08855	COG0582	viral genome integration into host DNA
BS653_RS08860	COG0789	Transcriptional regulator
BS653_RS08880	COG1174	glycine betaine transport
BS653_RS08885	COG1125	glycine betaine transport
BS653_RS08890	COG1174	glycine betaine transport
BS653_RS08895	COG1732	Glycine betaine
BS653_RS08900	COG1472	Belongs to the glycosyl hydrolase 3 family
BS653_RS08905	COG0277	FAD linked oxidase domain protein
BS653_RS08910	COG1686	Belongs to the peptidase S11 family
BS653_RS08920	COG0586	Pfam SNARE associated Golgi protein
BS653_RS08960	COG1346	cytolysis
BS653_RS08970	COG2949	membrane
BS653_RS08980	COG0493	'glutamate synthase
BS653_RS08990	COG4211	Belongs to the binding-protein-dependent transport system permease family
BS653_RS08995	COG1129	ABC transporter
BS653_RS09000	COG1879	ABC-type sugar transport system periplasmic component
BS653_RS09005	COG1609	Transcriptional regulator
BS653_RS09015	COG2311	Membrane
BS653_RS09050	COG0833	amino acid
BS653_RS09060	COG0583	DNA-binding transcription factor activity
BS653_RS09065	COG2855	membrane
BS653_RS09075	COG1522	sequence-specific DNA binding
BS653_RS09075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS653_RS09080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS653_RS09095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS653_RS09100	COG2313	pseudouridylate synthase activity
BS653_RS09105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS653_RS09110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS09110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS09110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BS653_RS09115	COG1105	Belongs to the carbohydrate kinase PfkB family
BS653_RS09120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS09120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS09125	COG2814	Major facilitator Superfamily
BS653_RS09145	COG0246	Mannitol dehydrogenase
BS653_RS09150	COG0523	cobalamin synthesis protein
BS653_RS09155	COG0671	phosphoesterase, PA-phosphatase related
BS653_RS09160	COG0791	NLP P60 protein
BS653_RS09165	COG2200	EAL domain
BS653_RS09170	COG4166	transmembrane transport
BS653_RS09175	COG4174	ABC transporter (Permease)
BS653_RS09180	COG4239	(ABC) transporter, permease
BS653_RS09185	COG4172	Belongs to the ABC transporter superfamily
BS653_RS09200	COG2814	Major facilitator Superfamily
BS653_RS09205	COG1187	pseudouridine synthase activity
BS653_RS09215	COG1061	Type III restriction enzyme res subunit
BS653_RS09235	COG3083	sulfuric ester hydrolase activity
BS653_RS09250	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS09260	COG2197	response regulator
BS653_RS09265	COG3088	subunit of a heme lyase
BS653_RS09265	COG4235	cytochrome complex assembly
BS653_RS09270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS653_RS09275	COG1138	Cytochrome C-type biogenesis protein
BS653_RS09285	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS653_RS09290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS653_RS09295	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS653_RS09305	COG3005	denitrification pathway
BS653_RS09310	COG3043	anaerobic respiration
BS653_RS09315	COG0348	domain, Protein
BS653_RS09320	COG0437	4 iron, 4 sulfur cluster binding
BS653_RS09330	COG3062	negative regulation of establishment of protein localization
BS653_RS09335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS653_RS09335	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS653_RS09365	COG4615	Cyclic peptide transporter
BS653_RS09370	COG3145	DNA-N1-methyladenine dioxygenase activity
BS653_RS09375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS653_RS09375	COG2169	Transcriptional regulator
BS653_RS09380	COG1477	protein flavinylation
BS653_RS09400	COG2198	Histidine kinase
BS653_RS09400	COG0642	Histidine kinase
BS653_RS09405	COG2197	response regulator
BS653_RS09410	COG0784	Response regulator, receiver
BS653_RS09410	COG2205	protein histidine kinase activity
BS653_RS09415	COG4676	Protein conserved in bacteria
BS653_RS09420	COG5445	Predicted secreted protein (DUF2300)
BS653_RS09435	COG2373	Large extracellular alpha-helical protein
BS653_RS09440	COG3234	Protein of unknown function (DUF1175)
BS653_RS09450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS653_RS09460	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS09465	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS09475	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS09485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS653_RS09490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS653_RS09495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS653_RS09500	COG3642	lipopolysaccharide core region biosynthetic process
BS653_RS09510	COG0583	DNA-binding transcription factor activity
BS653_RS09515	COG0584	glycerophosphoryl diester phosphodiesterase
BS653_RS09520	COG2271	Major facilitator Superfamily
BS653_RS09525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BS653_RS09535	COG0247	lactate metabolic process
BS653_RS09540	COG5464	transposase or invertase
BS653_RS09610	COG0318	PFAM AMP-dependent synthetase and ligase
BS653_RS09620	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BS653_RS09635	COG1169	isochorismate synthase
BS653_RS09640	COG4575	ribosome binding
BS653_RS09645	COG2153	protein acetylation
BS653_RS09655	COG5160	protein modification by small protein removal
BS653_RS09685	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS653_RS09690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS653_RS09700	COG0839	Belongs to the complex I subunit 6 family
BS653_RS09720	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BS653_RS09725	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BS653_RS09745	COG0583	DNA-binding transcription factor activity
BS653_RS09755	COG0436	Aminotransferase
BS653_RS09765	COG0490	domain, Protein
BS653_RS09765	COG0471	metal ion transport
BS653_RS09770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS653_RS09785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BS653_RS09790	COG0280	phosphate acetyltransferase
BS653_RS09790	COG0857	belongs to the CobB CobQ family
BS653_RS09795	COG1288	antiporter activity
BS653_RS09805	COG0622	Phosphoesterase
BS653_RS09810	COG0625	glutathione transferase activity
BS653_RS09815	COG0625	glutathione transferase activity
BS653_RS09820	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BS653_RS09825	COG1090	epimerase
BS653_RS09830	COG5464	transposase or invertase
BS653_RS09835	COG4598	ABC transporter
BS653_RS09840	COG4160	amino acid transport
BS653_RS09845	COG4215	(ABC) transporter
BS653_RS09850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS653_RS09855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS653_RS09860	COG0163	prenyltransferase activity
BS653_RS09865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BS653_RS09870	COG1286	toxin biosynthetic process
BS653_RS09875	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BS653_RS09880	COG0285	dihydrofolate synthase activity
BS653_RS09890	COG0586	Pfam SNARE associated Golgi protein
BS653_RS09900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BS653_RS09925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS653_RS09940	COG3101	peptidyl-lysine hydroxylation
BS653_RS09945	COG0730	response to heat
BS653_RS09975	COG3539	Fimbrial protein
BS653_RS09980	COG3539	Fimbrial protein
BS653_RS09985	COG3539	Fimbrial protein
BS653_RS10000	COG3188	usher protein
BS653_RS10005	COG3539	Fimbrial protein
BS653_RS10015	COG2062	phosphohistidine phosphatase, SixA
BS653_RS10030	COG3691	Protein conserved in bacteria
BS653_RS10075	COG0582	viral genome integration into host DNA
BS653_RS10085	COG3385	transposase activity
BS653_RS10100	COG2610	gluconate transmembrane transporter activity
BS653_RS10110	COG0477	Major facilitator Superfamily
BS653_RS10115	COG1566	PFAM secretion protein HlyD family protein
BS653_RS10120	COG2197	response regulator
BS653_RS10125	COG0784	Response regulator, receiver
BS653_RS10125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS653_RS10125	COG2198	Histidine kinase
BS653_RS10125	COG2205	protein histidine kinase activity
BS653_RS10130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BS653_RS10135	COG0679	Auxin Efflux Carrier
BS653_RS10140	COG0028	Belongs to the TPP enzyme family
BS653_RS10165	COG1560	Kdo2-lipid A biosynthetic process
BS653_RS10175	COG0436	Aminotransferase
BS653_RS10185	COG3279	Response regulator of the LytR AlgR family
BS653_RS10200	COG1363	Peptidase, m42
BS653_RS10210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS10240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS653_RS10260	COG3415	Transposase
BS653_RS10265	COG3415	Transposase
BS653_RS10300	COG0583	DNA-binding transcription factor activity
BS653_RS10305	COG0385	Bile acid
BS653_RS10310	COG3530	Putative quorum-sensing-regulated virulence factor
BS653_RS10330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS653_RS10335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS10340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS653_RS10345	COG2190	(PTS) system
BS653_RS10365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS653_RS10375	COG4208	sulfate ABC transporter
BS653_RS10380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BS653_RS10385	COG4150	thiosulfate binding
BS653_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS10415	COG2837	iron assimilation
BS653_RS10435	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS653_RS10450	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BS653_RS10455	COG4816	utilization protein
BS653_RS10500	COG0076	glutamate decarboxylase activity
BS653_RS10505	COG0076	glutamate decarboxylase activity
BS653_RS10510	COG0531	amino acid
BS653_RS10515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS653_RS10525	COG4819	ethanolamine utilization protein
BS653_RS10530	COG4917	ethanolamine utilization protein
BS653_RS10535	COG4810	utilization protein
BS653_RS10540	COG0280	phosphate acetyltransferase
BS653_RS10540	COG0281	malic enzyme
BS653_RS10555	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BS653_RS10560	COG5342	invasion associated locus B
BS653_RS10570	COG0493	'glutamate synthase
BS653_RS10570	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS653_RS10580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS653_RS10595	COG1393	Belongs to the ArsC family
BS653_RS10610	COG0400	carboxylic ester hydrolase activity
BS653_RS10620	COG2321	neutral zinc metallopeptidase
BS653_RS10630	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BS653_RS10640	COG2716	regulation of RNA biosynthetic process
BS653_RS10645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BS653_RS10650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS653_RS10655	COG0651	ATP synthesis coupled electron transport
BS653_RS10660	COG0651	ATP synthesis coupled electron transport
BS653_RS10665	COG0650	Formate hydrogenlyase subunit 4
BS653_RS10670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS653_RS10675	COG4237	Hydrogenase 4 membrane
BS653_RS10680	COG0651	ATP synthesis coupled electron transport
BS653_RS10690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS653_RS10695	COG3260	NADH ubiquinone oxidoreductase 20
BS653_RS10705	COG3604	Transcriptional regulator
BS653_RS10710	COG3604	Transcriptional regulator
BS653_RS10720	COG0628	permease
BS653_RS10725	COG4783	chaperone-mediated protein folding
BS653_RS10730	COG1393	Belongs to the ArsC family
BS653_RS10740	COG2233	PERMEase
BS653_RS10760	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BS653_RS10765	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BS653_RS10770	COG0248	Ppx GppA phosphatase
BS653_RS10775	COG2200	EAL domain
BS653_RS10785	COG2200	EAL domain
BS653_RS10805	COG3133	Outer membrane lipoprotein
BS653_RS10820	COG0517	IMP dehydrogenase activity
BS653_RS10820	COG0516	GMP reductase activity
BS653_RS10830	COG1645	bacterial-type flagellum-dependent swarming motility
BS653_RS10845	COG2976	Protein conserved in bacteria
BS653_RS10875	COG4953	penicillin-binding protein 1C
BS653_RS10880	COG3547	Transposase (IS116 IS110 IS902 family)
BS653_RS10885	COG2897	thiosulfate sulfurtransferase activity
BS653_RS10900	COG2975	iron-sulfur cluster assembly
BS653_RS10905	COG0633	Ferredoxin
BS653_RS10925	COG0822	iron-sulfur transferase activity
BS653_RS10945	COG0483	inositol monophosphate 1-phosphatase activity
BS653_RS10950	COG1073	alpha beta
BS653_RS10955	COG3711	transcriptional antiterminator
BS653_RS10960	COG2814	Major facilitator Superfamily
BS653_RS10965	COG0583	DNA-binding transcription factor activity
BS653_RS10995	COG2259	Doxx family
BS653_RS11000	COG2017	converts alpha-aldose to the beta-anomer
BS653_RS11005	COG1063	alcohol dehydrogenase
BS653_RS11010	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS653_RS11015	COG1129	ABC transporter
BS653_RS11025	COG0457	Tetratricopeptide repeat
BS653_RS11030	COG1940	carbohydrate kinase activity
BS653_RS11045	COG0347	Belongs to the P(II) protein family
BS653_RS11050	COG2204	response regulator
BS653_RS11055	COG3170	Tfp pilus assembly protein FimV
BS653_RS11060	COG2205	protein histidine kinase activity
BS653_RS11080	COG0560	Phosphoserine phosphatase
BS653_RS11085	COG1737	Transcriptional regulator
BS653_RS11090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS653_RS11140	COG4771	TonB-dependent receptor
BS653_RS11165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS653_RS11215	COG0681	Belongs to the peptidase S26 family
BS653_RS11225	COG3086	response to oxidative stress
BS653_RS11230	COG3026	antisigma factor binding
BS653_RS11235	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BS653_RS11240	COG1595	DNA-templated transcription, initiation
BS653_RS11245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BS653_RS11250	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BS653_RS11260	COG0513	Belongs to the DEAD box helicase family
BS653_RS11265	COG0583	DNA-binding transcription factor activity
BS653_RS11285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS653_RS11295	COG3118	belongs to the thioredoxin family
BS653_RS11300	COG3148	PFAM DTW domain containing protein
BS653_RS11305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS653_RS11305	COG0045	succinate-CoA ligase (ADP-forming) activity
BS653_RS11305	COG1042	CoA-binding domain protein
BS653_RS11310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS653_RS11315	COG5544	Lipoprotein
BS653_RS11320	COG0477	Major facilitator Superfamily
BS653_RS11355	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BS653_RS11360	COG0564	pseudouridine synthase activity
BS653_RS11370	COG0542	response to heat
BS653_RS11385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BS653_RS11390	COG1605	Chorismate mutase
BS653_RS11390	COG0077	Prephenate dehydratase
BS653_RS11395	COG0287	Prephenate dehydrogenase
BS653_RS11395	COG1605	Chorismate mutase
BS653_RS11400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BS653_RS11420	COG2885	chlorophyll binding
BS653_RS11445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BS653_RS11450	COG4137	Cytochrome C assembly protein
BS653_RS11455	COG4536	flavin adenine dinucleotide binding
BS653_RS11475	COG0497	DNA recombination
BS653_RS11480	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BS653_RS11490	COG2867	negative regulation of translational initiation
BS653_RS11505	COG0582	viral genome integration into host DNA
BS653_RS11530	COG0366	Alpha amylase catalytic
BS653_RS11540	COG0579	oxidoreductase
BS653_RS11555	COG1113	amino acid transport
BS653_RS11560	COG1802	Transcriptional regulator
BS653_RS11565	COG1652	LysM domain
BS653_RS11570	COG0401	homolog of Blt101
BS653_RS11580	COG0640	Transcriptional regulator
BS653_RS11585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS653_RS11590	COG2916	Histone family protein nucleoid-structuring protein H-NS
BS653_RS11605	COG4575	ribosome binding
BS653_RS11615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BS653_RS11625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS653_RS11630	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS653_RS11635	COG4175	Glycine betaine
BS653_RS11640	COG4176	ABC-type proline glycine betaine transport system permease component
BS653_RS11645	COG2113	Glycine betaine
BS653_RS11655	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BS653_RS11665	COG1846	Transcriptional regulator
BS653_RS11675	COG2814	Major facilitator Superfamily
BS653_RS11690	COG1238	metal cluster binding
BS653_RS11695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS653_RS11725	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BS653_RS11745	COG1546	Belongs to the CinA family
BS653_RS11750	COG2951	lytic endotransglycosylase activity
BS653_RS11760	COG3732	PTS system glucitol sorbitol-specific
BS653_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS11775	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS11780	COG1349	DNA-binding transcription factor activity
BS653_RS11805	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BS653_RS11810	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS653_RS11815	COG1609	Transcriptional regulator
BS653_RS11820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS653_RS11825	COG3261	NADH dehydrogenase
BS653_RS11825	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BS653_RS11830	COG0650	Formate hydrogenlyase subunit 4
BS653_RS11840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS653_RS11855	COG0375	protein maturation
BS653_RS11860	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BS653_RS11865	COG0298	carbon dioxide binding
BS653_RS11870	COG0409	Hydrogenase expression formation protein
BS653_RS11875	COG0309	Hydrogenase expression formation protein (HypE)
BS653_RS11880	COG3604	Transcriptional regulator
BS653_RS11910	COG1349	DNA-binding transcription factor activity
BS653_RS11915	COG2084	Dehydrogenase
BS653_RS11920	COG2084	Dehydrogenase
BS653_RS11925	COG3395	kinase activity
BS653_RS11945	COG3423	Transcriptional regulator
BS653_RS11955	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BS653_RS11975	COG4942	peptidase
BS653_RS11975	COG1388	LysM domain
BS653_RS12035	COG2234	aminopeptidase activity
BS653_RS12070	COG0720	synthase
BS653_RS12075	COG0644	oxidoreductase
BS653_RS12080	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BS653_RS12090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BS653_RS12095	COG2086	electron transfer activity
BS653_RS12100	COG0477	Major facilitator Superfamily
BS653_RS12105	COG0277	FAD linked oxidase domain protein
BS653_RS12115	COG0602	queuosine metabolic process
BS653_RS12150	COG3956	TIGRFAM MazG family protein
BS653_RS12155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BS653_RS12170	COG4948	Mandelate Racemase Muconate Lactonizing
BS653_RS12175	COG4948	Mandelate Racemase Muconate Lactonizing
BS653_RS12180	COG2271	Major facilitator Superfamily
BS653_RS12185	COG0716	FMN binding
BS653_RS12190	COG0564	pseudouridine synthase activity
BS653_RS12195	COG3098	single-species biofilm formation
BS653_RS12210	COG1611	Belongs to the LOG family
BS653_RS12215	COG3385	transposase activity
BS653_RS12225	COG0814	amino acid
BS653_RS12230	COG1760	l-serine dehydratase
BS653_RS12240	COG1454	alcohol dehydrogenase
BS653_RS12245	COG0235	Class ii aldolase
BS653_RS12250	COG0738	Major facilitator superfamily
BS653_RS12260	COG1070	Carbohydrate kinase
BS653_RS12265	COG1070	Carbohydrate kinase
BS653_RS12270	COG1070	Carbohydrate kinase
BS653_RS12280	COG1349	DNA-binding transcription factor activity
BS653_RS12290	COG2363	Small membrane protein
BS653_RS12295	COG0583	DNA-binding transcription factor activity
BS653_RS12305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS653_RS12310	COG2166	iron-sulfur cluster assembly
BS653_RS12315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BS653_RS12320	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BS653_RS12340	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS653_RS12350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BS653_RS12355	COG1074	ATP-dependent DNA helicase activity
BS653_RS12365	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BS653_RS12370	COG4967	type IV pilus modification protein PilV
BS653_RS12380	COG4795	General secretion pathway protein
BS653_RS12400	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BS653_RS12415	COG0861	Integral membrane protein TerC family
BS653_RS12425	COG0667	Aldo Keto reductase
BS653_RS12440	COG1609	Transcriptional regulator
BS653_RS12450	COG0583	DNA-binding transcription factor activity
BS653_RS12455	COG1794	racemase activity, acting on amino acids and derivatives
BS653_RS12460	COG2814	Major facilitator Superfamily
BS653_RS12465	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS12475	COG0183	Belongs to the thiolase family
BS653_RS12480	COG0814	amino acid
BS653_RS12490	COG3387	PFAM Glycoside hydrolase 15-related
BS653_RS12540	COG4942	peptidase
BS653_RS12555	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BS653_RS12560	COG2080	2 iron, 2 sulfur cluster binding
BS653_RS12585	COG2233	PERMEase
BS653_RS12610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BS653_RS12615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BS653_RS12625	COG0716	FMN binding
BS653_RS12645	COG1272	protein, Hemolysin III
BS653_RS12655	COG2723	6-phospho-beta-galactosidase activity
BS653_RS12660	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS12680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS653_RS12685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS653_RS12690	COG0006	proline dipeptidase activity
BS653_RS12715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BS653_RS12730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BS653_RS12755	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BS653_RS12755	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BS653_RS12760	COG1703	isobutyryl-CoA mutase activity
BS653_RS12765	COG1024	Enoyl-CoA hydratase
BS653_RS12775	COG0583	DNA-binding transcription factor activity
BS653_RS12780	COG2968	Membrane
BS653_RS12790	COG0668	transmembrane transport
BS653_RS12795	COG0191	fructose-bisphosphate aldolase activity
BS653_RS12830	COG1122	ATPase activity
BS653_RS12835	COG1122	ATPase activity
BS653_RS12840	COG1072	(Pantothenic acid kinase))
BS653_RS12850	COG1494	fructose-1,6-bisphosphatase
BS653_RS12855	COG1063	alcohol dehydrogenase
BS653_RS12865	COG0330	HflC and HflK could
BS653_RS12870	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BS653_RS12875	COG0501	Belongs to the peptidase M48B family
BS653_RS12920	COG2814	Major facilitator Superfamily
BS653_RS12930	COG2356	endonuclease I
BS653_RS12935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BS653_RS12955	COG2805	Type II/IV secretion system protein
BS653_RS12960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BS653_RS12965	COG0762	integral membrane protein
BS653_RS12980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS653_RS12990	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BS653_RS13010	COG0252	asparaginase activity
BS653_RS13020	COG3171	Protein conserved in bacteria
BS653_RS13035	COG1194	a g-specific adenine glycosylase
BS653_RS13050	COG2211	Major facilitator Superfamily
BS653_RS13055	COG1982	Orn Lys Arg decarboxylase major
BS653_RS13065	COG1811	Na channel or pump
BS653_RS13075	COG0582	viral genome integration into host DNA
BS653_RS13085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS653_RS13085	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BS653_RS13095	COG3547	Transposase (IS116 IS110 IS902 family)
BS653_RS13100	COG4372	Transposase
BS653_RS13115	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS13140	COG3328	transposase activity
BS653_RS13155	COG3344	reverse transcriptase
BS653_RS13240	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS13245	COG2020	methyltransferase activity
BS653_RS13280	COG2003	Belongs to the UPF0758 family
BS653_RS13350	COG1620	l-lactate permease
BS653_RS13360	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BS653_RS13370	COG0277	FAD linked oxidase domain protein
BS653_RS13380	COG2186	Transcriptional regulator
BS653_RS13395	COG0318	PFAM AMP-dependent synthetase and ligase
BS653_RS13405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS653_RS13420	COG0795	lipopolysaccharide-transporting ATPase activity
BS653_RS13425	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BS653_RS13435	COG2244	polysaccharide biosynthetic process
BS653_RS13440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BS653_RS13445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BS653_RS13450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BS653_RS13455	COG0306	phosphate transporter
BS653_RS13460	COG0754	glutathionylspermidine amidase activity
BS653_RS13465	COG0625	glutathione transferase activity
BS653_RS13470	COG0298	carbon dioxide binding
BS653_RS13480	COG1773	rubredoxin
BS653_RS13485	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BS653_RS13490	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BS653_RS13495	COG5557	Pfam Polysulphide reductase, NrfD
BS653_RS13500	COG0437	4 iron, 4 sulfur cluster binding
BS653_RS13505	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BS653_RS13525	COG0667	Aldo Keto reductase
BS653_RS13535	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS13540	COG0848	biopolymer transport protein
BS653_RS13545	COG0811	peptide transport
BS653_RS13555	COG0626	cystathionine gamma-synthase activity
BS653_RS13560	COG0586	Pfam SNARE associated Golgi protein
BS653_RS13565	COG2207	Transcriptional regulator
BS653_RS13570	COG1979	alcohol dehydrogenase
BS653_RS13575	COG0656	L-ascorbic acid biosynthetic process
BS653_RS13585	COG4238	major outer membrane lipoprotein
BS653_RS13595	COG2132	Multicopper oxidase
BS653_RS13600	COG0204	Acyl-transferase
BS653_RS13605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS653_RS13615	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BS653_RS13620	COG3111	PFAM Bacterial OB fold (BOF) protein
BS653_RS13625	COG0745	RESPONSE REGULATOR receiver
BS653_RS13630	COG0642	Histidine kinase
BS653_RS13645	COG2249	NAD(P)H dehydrogenase (quinone) activity
BS653_RS13650	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BS653_RS13655	COG0187	DNA topoisomerase II activity
BS653_RS13660	COG3150	esterase
BS653_RS13665	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BS653_RS13670	COG3151	Protein conserved in bacteria
BS653_RS13675	COG0494	nUDIX hydrolase
BS653_RS13680	COG1538	Outer membrane efflux protein
BS653_RS13695	COG0754	glutathionylspermidine amidase activity
BS653_RS13700	COG3384	dioxygenase
BS653_RS13720	COG2960	long-chain fatty acid transporting porin activity
BS653_RS13735	COG3539	Fimbrial protein
BS653_RS13750	COG2268	Band 7 protein
BS653_RS13775	COG3025	triphosphatase activity
BS653_RS13785	COG4991	sh3 domain protein
BS653_RS13800	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BS653_RS13810	COG0583	DNA-binding transcription factor activity
BS653_RS13825	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BS653_RS13845	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BS653_RS13850	COG0358	DNA primase activity
BS653_RS13860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BS653_RS13890	COG1695	Transcriptional regulator
BS653_RS13920	COG1609	Transcriptional regulator
BS653_RS13925	COG3250	beta-galactosidase activity
BS653_RS13930	COG2731	YhcH YjgK YiaL family protein
BS653_RS13935	COG0531	amino acid
BS653_RS13945	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BS653_RS13945	COG3408	Glycogen debranching enzyme
BS653_RS13950	COG0446	pyridine nucleotide-disulphide oxidoreductase
BS653_RS13950	COG1902	pentaerythritol trinitrate reductase activity
BS653_RS13955	COG5499	transcription regulator containing HTH domain
BS653_RS13960	COG4680	protein conserved in bacteria
BS653_RS13975	COG1451	nucleotide metabolic process
BS653_RS13980	COG2949	membrane
BS653_RS13985	COG0673	inositol 2-dehydrogenase activity
BS653_RS13990	COG0861	Integral membrane protein TerC family
BS653_RS14010	COG2721	sulfolactate sulfo-lyase activity
BS653_RS14020	COG2271	Major facilitator Superfamily
BS653_RS14040	COG2186	Transcriptional regulator
BS653_RS14045	COG0586	Pfam SNARE associated Golgi protein
BS653_RS14055	COG1422	Protein of unknown function (DUF1090)
BS653_RS14060	COG4575	ribosome binding
BS653_RS14065	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BS653_RS14075	COG2259	Doxx family
BS653_RS14080	COG0435	Glutathione S-transferase
BS653_RS14085	COG3152	Membrane
BS653_RS14095	COG0583	DNA-binding transcription factor activity
BS653_RS14100	COG1741	Belongs to the pirin family
BS653_RS14115	COG0814	amino acid
BS653_RS14120	COG1760	l-serine dehydratase
BS653_RS14125	COG0251	oxidation-reduction process
BS653_RS14130	COG1882	Formate acetyltransferase
BS653_RS14135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BS653_RS14145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BS653_RS14155	COG0583	DNA-binding transcription factor activity
BS653_RS14185	COG1929	Belongs to the glycerate kinase type-1 family
BS653_RS14190	COG2084	Dehydrogenase
BS653_RS14200	COG2271	Major facilitator Superfamily
BS653_RS14205	COG2721	sulfolactate sulfo-lyase activity
BS653_RS14210	COG1349	DNA-binding transcription factor activity
BS653_RS14225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS653_RS14235	COG3716	PTS system mannose fructose sorbose family IID component
BS653_RS14240	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS14245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS653_RS14255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS653_RS14260	COG3715	PTS system
BS653_RS14265	COG3716	PTS system mannose fructose sorbose family IID component
BS653_RS14270	COG0363	glucosamine-6-phosphate deaminase activity
BS653_RS14275	COG3539	Fimbrial protein
BS653_RS14285	COG3539	Fimbrial protein
BS653_RS14290	COG3121	Chaperone
BS653_RS14295	COG3188	usher protein
BS653_RS14305	COG3188	usher protein
BS653_RS14310	COG3539	Fimbrial protein
BS653_RS14315	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BS653_RS14335	COG2823	Periplasmic or secreted lipoprotein
BS653_RS14340	COG0701	Predicted permease
BS653_RS14345	COG0702	epimerase
BS653_RS14350	COG0693	protein deglycase activity
BS653_RS14365	COG3153	acetyltransferase
BS653_RS14370	COG3154	lipid carrier protein
BS653_RS14375	COG0826	peptidase U32
BS653_RS14380	COG0826	peptidase U32
BS653_RS14385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS653_RS14390	COG0814	amino acid
BS653_RS14395	COG0513	Belongs to the DEAD box helicase family
BS653_RS14435	COG0195	Participates in both transcription termination and antitermination
BS653_RS14465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS653_RS14475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BS653_RS14480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS653_RS14490	COG1534	Rna-binding protein
BS653_RS14495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS653_RS14500	COG2027	D-alanyl-D-alanine carboxypeptidase
BS653_RS14510	COG0697	spore germination
BS653_RS14525	COG0142	geranyltranstransferase activity
BS653_RS14530	COG3423	Transcriptional regulator
BS653_RS14540	COG5007	Belongs to the BolA IbaG family
BS653_RS14545	COG3113	response to antibiotic
BS653_RS14550	COG2854	intermembrane phospholipid transfer
BS653_RS14555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BS653_RS14560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BS653_RS14565	COG1127	ABC transporter
BS653_RS14570	COG0530	calcium, potassium:sodium antiporter activity
BS653_RS14580	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BS653_RS14585	COG3117	lipopolysaccharide transmembrane transporter activity
BS653_RS14590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BS653_RS14595	COG1137	ATPase activity
BS653_RS14600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BS653_RS14605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BS653_RS14620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS14625	COG0515	serine threonine protein kinase
BS653_RS14635	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BS653_RS14640	COG2198	Histidine kinase
BS653_RS14640	COG0784	Response regulator, receiver
BS653_RS14640	COG5002	protein histidine kinase activity
BS653_RS14645	COG1242	4 iron, 4 sulfur cluster binding
BS653_RS14660	COG0069	glutamate synthase activity
BS653_RS14660	COG0067	glutamate synthase
BS653_RS14660	COG0070	glutamate synthase
BS653_RS14665	COG0493	'glutamate synthase
BS653_RS14670	COG4804	nuclease activity
BS653_RS14680	COG2731	YhcH YjgK YiaL family protein
BS653_RS14715	COG3069	C4-dicarboxylate transmembrane transporter activity
BS653_RS14720	COG2969	positive regulation of protein catabolic process
BS653_RS14725	COG0625	glutathione transferase activity
BS653_RS14745	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BS653_RS14750	COG3105	Protein conserved in bacteria
BS653_RS14760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS653_RS14780	COG2732	(Barnase) inhibitor
BS653_RS14800	COG0583	DNA-binding transcription factor activity
BS653_RS14805	COG0312	modulator of DNA gyrase
BS653_RS14810	COG3164	Protein of unknown function
BS653_RS14815	COG1530	ribonuclease E activity
BS653_RS14825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BS653_RS14830	COG1792	Involved in formation and maintenance of cell shape
BS653_RS14835	COG1077	Cell shape determining protein MreB Mrl
BS653_RS14850	COG2200	EAL domain
BS653_RS14850	COG2199	diguanylate cyclase activity
BS653_RS14855	COG0604	alcohol dehydrogenase
BS653_RS14865	COG0511	ligase activity, forming carbon-carbon bonds
BS653_RS14870	COG0439	Biotin carboxylase
BS653_RS14875	COG3924	membrane
BS653_RS14880	COG4145	pantothenate transmembrane transporter activity
BS653_RS14900	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BS653_RS14920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS653_RS14935	COG4597	amino acid ABC transporter
BS653_RS14940	COG0765	amino acid transport
BS653_RS14945	COG1126	abc transporter atp-binding protein
BS653_RS14985	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BS653_RS15005	COG0551	DNA topoisomerase type I activity
BS653_RS15015	COG0758	DNA mediated transformation
BS653_RS15035	COG0569	domain protein
BS653_RS15045	COG3436	PFAM IS66 Orf2 family protein
BS653_RS15095	COG0201	protein transport
BS653_RS15185	COG0089	rRNA binding
BS653_RS15265	COG2964	Protein conserved in bacteria
BS653_RS15270	COG0545	Peptidyl-prolyl cis-trans isomerase
BS653_RS15280	COG1047	Peptidyl-prolyl cis-trans
BS653_RS15285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BS653_RS15305	COG0488	(ABC) transporter
BS653_RS15310	COG0429	hydrolase of the alpha beta-hydrolase fold
BS653_RS15320	COG3954	Phosphoribulokinase
BS653_RS15325	COG1765	OsmC-like protein
BS653_RS15335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS653_RS15340	COG1289	transmembrane transporter activity
BS653_RS15350	COG0512	Glutamine amidotransferase of anthranilate synthase
BS653_RS15355	COG2184	nucleotidyltransferase activity
BS653_RS15365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS653_RS15375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS653_RS15380	COG2146	nitrite reductase [NAD(P)H] activity
BS653_RS15385	COG2116	formate transmembrane transporter activity
BS653_RS15400	COG0531	amino acid
BS653_RS15405	COG0531	amino acid
BS653_RS15410	COG2222	sugar isomerase
BS653_RS15415	COG1082	Xylose isomerase domain protein TIM barrel
BS653_RS15435	COG0626	cystathionine gamma-synthase activity
BS653_RS15450	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BS653_RS15455	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BS653_RS15460	COG3457	Alanine racemase
BS653_RS15470	COG2188	Transcriptional regulator
BS653_RS15485	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BS653_RS15490	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BS653_RS15495	COG3266	domain, Protein
BS653_RS15515	COG4796	Type ii and iii secretion system protein
BS653_RS15530	COG3166	PFAM Fimbrial assembly family protein
BS653_RS15535	COG4972	Pilus assembly protein
BS653_RS15540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BS653_RS15545	COG0494	nUDIX hydrolase
BS653_RS15555	COG1011	Hydrolase
BS653_RS15560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BS653_RS15570	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BS653_RS15600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS653_RS15605	COG2183	response to ionizing radiation
BS653_RS15620	COG1918	ferrous iron import across plasma membrane
BS653_RS15640	COG5464	transposase or invertase
BS653_RS15675	COG2610	gluconate transmembrane transporter activity
BS653_RS15680	COG1640	4-alpha-glucanotransferase
BS653_RS15685	COG0058	SHG alpha-glucan phosphorylase activity
BS653_RS15700	COG1690	Belongs to the RtcB family
BS653_RS15705	COG4650	regulator
BS653_RS15710	COG1349	DNA-binding transcription factor activity
BS653_RS15725	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BS653_RS15735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BS653_RS15740	COG3385	transposase activity
BS653_RS15745	COG0058	SHG alpha-glucan phosphorylase activity
BS653_RS15770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BS653_RS15775	COG2095	MarC family integral membrane protein
BS653_RS15780	COG2610	gluconate transmembrane transporter activity
BS653_RS15785	COG3265	gluconokinase activity
BS653_RS15790	COG1609	Transcriptional regulator
BS653_RS15795	COG1741	Belongs to the pirin family
BS653_RS15800	COG0673	inositol 2-dehydrogenase activity
BS653_RS15810	COG1247	-acetyltransferase
BS653_RS15815	COG0405	Gamma-glutamyltransferase
BS653_RS15825	COG0584	glycerophosphoryl diester phosphodiesterase
BS653_RS15850	COG0410	ABC transporter
BS653_RS15855	COG0411	ABC transporter
BS653_RS15860	COG4177	L-phenylalanine transmembrane transporter activity
BS653_RS15865	COG0559	Belongs to the binding-protein-dependent transport system permease family
BS653_RS15870	COG0683	leucine binding
BS653_RS15880	COG0456	acetyltransferase
BS653_RS15885	COG0683	leucine binding
BS653_RS15890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BS653_RS15895	COG2177	Part of the ABC transporter FtsEX involved in
BS653_RS15900	COG2884	Cell division ATP-binding protein ftsE
BS653_RS15905	COG0552	protein localization to endoplasmic reticulum
BS653_RS15910	COG0742	ribosomal rna small subunit methyltransferase
BS653_RS15915	COG3776	membrane
BS653_RS15925	COG3714	YhhN family
BS653_RS15940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BS653_RS15955	COG0628	permease
BS653_RS15960	COG2091	lysine biosynthetic process via aminoadipic acid
BS653_RS15965	COG0747	negative chemotaxis
BS653_RS15970	COG0601	transmembrane transport
BS653_RS15975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS653_RS16005	COG0842	Transport permease protein
BS653_RS16010	COG1129	ABC transporter
BS653_RS16010	COG0842	Transport permease protein
BS653_RS16015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS653_RS16110	COG2081	HI0933 family
BS653_RS16115	COG0306	phosphate transporter
BS653_RS16125	COG0589	response to stress
BS653_RS16140	COG0339	signal peptide processing
BS653_RS16145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BS653_RS16150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS653_RS16175	COG1393	Belongs to the ArsC family
BS653_RS16180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS653_RS16185	COG0640	Transcriptional regulator
BS653_RS16205	COG3065	identical protein binding
BS653_RS16235	COG3247	response to pH
BS653_RS16240	COG2771	luxR family
BS653_RS16250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS653_RS16265	COG3385	transposase activity
BS653_RS16270	COG2197	response regulator
BS653_RS16275	COG0583	DNA-binding transcription factor activity
BS653_RS16280	COG1295	ribonuclease BN
BS653_RS16285	COG0477	Major facilitator Superfamily
BS653_RS16290	COG2982	Protein involved in outer membrane biogenesis
BS653_RS16295	COG2200	EAL domain
BS653_RS16310	COG0612	Peptidase, M16
BS653_RS16330	COG2200	EAL domain
BS653_RS16330	COG2199	diguanylate cyclase activity
BS653_RS16335	COG0457	Tetratricopeptide repeat
BS653_RS16335	COG3118	belongs to the thioredoxin family
BS653_RS16340	COG0457	Tetratricopeptide repeat
BS653_RS16340	COG3118	belongs to the thioredoxin family
BS653_RS16345	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BS653_RS16350	COG1215	transferase activity, transferring glycosyl groups
BS653_RS16385	COG2194	sulfuric ester hydrolase activity
BS653_RS16435	COG0814	amino acid
BS653_RS16440	COG4608	Belongs to the ABC transporter superfamily
BS653_RS16445	COG0444	Belongs to the ABC transporter superfamily
BS653_RS16450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS653_RS16455	COG0601	transmembrane transport
BS653_RS16465	COG0747	negative chemotaxis
BS653_RS16475	COG2194	sulfuric ester hydrolase activity
BS653_RS16480	COG2223	nitrite transmembrane transporter activity
BS653_RS16490	COG5571	outer membrane autotransporter
BS653_RS16495	COG2818	Glycosylase
BS653_RS16500	COG0456	acetyltransferase
BS653_RS16505	COG0243	molybdopterin cofactor binding
BS653_RS16510	COG2885	chlorophyll binding
BS653_RS16530	COG1278	Cold shock
BS653_RS16550	COG1858	cytochrome C peroxidase
BS653_RS16565	COG2207	Transcriptional regulator
BS653_RS16580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS653_RS16610	COG3274	enterobacterial common antigen metabolic process
BS653_RS16615	COG4682	membrane
BS653_RS16620	COG4682	membrane
BS653_RS16625	COG1070	Carbohydrate kinase
BS653_RS16635	COG4213	ABC transporter substrate-binding protein
BS653_RS16645	COG4214	carbohydrate transport
BS653_RS16655	COG2992	FlgJ-related protein
BS653_RS16660	COG0366	Alpha amylase catalytic
BS653_RS16665	COG3977	Valine--pyruvate aminotransferase
BS653_RS16670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS653_RS16675	COG1414	Transcriptional regulator
BS653_RS16685	COG2731	YhcH YjgK YiaL family protein
BS653_RS16695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BS653_RS16700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BS653_RS16720	COG1012	belongs to the aldehyde dehydrogenase family
BS653_RS16725	COG1454	alcohol dehydrogenase
BS653_RS16730	COG3276	selenocysteine insertion sequence binding
BS653_RS16740	COG0625	glutathione transferase activity
BS653_RS16745	COG1566	PFAM secretion protein HlyD family protein
BS653_RS16755	COG2213	PTS system mannitol-specific
BS653_RS16755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS16765	COG3722	fumarate hydratase activity
BS653_RS16805	COG1620	l-lactate permease
BS653_RS16810	COG2186	Transcriptional regulator
BS653_RS16820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BS653_RS16825	COG1045	serine acetyltransferase
BS653_RS16840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BS653_RS16845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS653_RS16860	COG4942	peptidase
BS653_RS16865	COG2861	carbohydrate metabolic process
BS653_RS16885	COG0156	8-amino-7-oxononanoate synthase activity
BS653_RS16900	COG0859	PFAM glycosyl transferase family 9
BS653_RS16905	COG0859	PFAM glycosyl transferase family 9
BS653_RS16925	COG3642	lipopolysaccharide core region biosynthetic process
BS653_RS16935	COG0515	serine threonine protein kinase
BS653_RS16940	COG0438	transferase activity, transferring glycosyl groups
BS653_RS16945	COG0859	PFAM glycosyl transferase family 9
BS653_RS16955	COG1519	Transferase
BS653_RS16985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS653_RS17015	COG1561	YicC-like family, N-terminal region
BS653_RS17025	COG3645	SOS response
BS653_RS17030	COG2860	membrane
BS653_RS17040	COG0194	GDP metabolic process
BS653_RS17050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BS653_RS17055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS653_RS17060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BS653_RS17065	COG0786	glutamate:sodium symporter activity
BS653_RS17070	COG2233	PERMEase
BS653_RS17075	COG2982	Protein involved in outer membrane biogenesis
BS653_RS17080	COG1501	Belongs to the glycosyl hydrolase 31 family
BS653_RS17095	COG0582	viral genome integration into host DNA
BS653_RS17195	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS17205	COG3188	usher protein
BS653_RS17225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BS653_RS17230	COG0573	inorganic phosphate transmembrane transporter activity
BS653_RS17235	COG0581	inorganic phosphate transmembrane transporter activity
BS653_RS17240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS653_RS17245	COG0704	Plays a role in the regulation of phosphate uptake
BS653_RS17250	COG3711	transcriptional antiterminator
BS653_RS17255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS653_RS17255	COG1263	PTS System
BS653_RS17255	COG2190	(PTS) system
BS653_RS17260	COG2723	6-phospho-beta-galactosidase activity
BS653_RS17270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS653_RS17275	COG2252	PERMEase
BS653_RS17280	COG0431	NADPH-dependent FMN reductase
BS653_RS17285	COG2091	lysine biosynthetic process via aminoadipic acid
BS653_RS17310	COG0814	amino acid
BS653_RS17365	COG0592	DNA-directed DNA polymerase activity
BS653_RS17375	COG0187	DNA topoisomerase II activity
BS653_RS17380	COG3753	Protein conserved in bacteria
BS653_RS17385	COG0561	phosphatase activity
BS653_RS17395	COG2186	Transcriptional regulator
BS653_RS17400	COG3734	2-keto-3-deoxy-galactonokinase
BS653_RS17405	COG0800	Aldolase
BS653_RS17420	COG2271	Major facilitator Superfamily
BS653_RS17430	COG0823	Involved in the tonB-independent uptake of proteins
BS653_RS17435	COG5645	(Lipo)protein
BS653_RS17455	COG2188	Transcriptional regulator
BS653_RS17470	COG2207	Transcriptional regulator
BS653_RS17475	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS653_RS17480	COG3119	arylsulfatase activity
BS653_RS17485	COG3119	arylsulfatase activity
BS653_RS17495	COG2149	membrane
BS653_RS17510	COG2814	Major facilitator Superfamily
BS653_RS17540	COG0028	Belongs to the TPP enzyme family
BS653_RS17545	COG0440	acetolactate synthase activity
BS653_RS17550	COG2197	response regulator
BS653_RS17555	COG3851	Histidine kinase
BS653_RS17560	COG2271	Major facilitator Superfamily
BS653_RS17565	COG2271	Major facilitator Superfamily
BS653_RS17575	COG2252	PERMEase
BS653_RS17755	COG3312	ion transport
BS653_RS17770	COG0716	FMN binding
BS653_RS17775	COG1522	sequence-specific DNA binding
BS653_RS17810	COG1129	ABC transporter
BS653_RS17825	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS653_RS17835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS653_RS17840	COG1609	Transcriptional regulator
BS653_RS17845	COG0477	Major facilitator Superfamily
BS653_RS17850	COG2186	Transcriptional regulator
BS653_RS17890	COG3085	chromosome segregation
BS653_RS17895	COG0606	chelatase, subunit chli
BS653_RS17900	COG0606	chelatase, subunit chli
BS653_RS17920	COG3978	acetolactate synthase activity
BS653_RS17925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS653_RS17935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BS653_RS17940	COG0583	DNA-binding transcription factor activity
BS653_RS17950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS653_RS17955	COG0210	DNA helicase
BS653_RS17975	COG3118	belongs to the thioredoxin family
BS653_RS17985	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BS653_RS17995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS653_RS18000	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BS653_RS18005	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BS653_RS18010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BS653_RS18015	COG1088	dTDP-glucose 4,6-dehydratase activity
BS653_RS18020	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BS653_RS18025	COG0456	acetyltransferase
BS653_RS18030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS653_RS18035	COG2244	polysaccharide biosynthetic process
BS653_RS18055	COG1113	amino acid transport
BS653_RS18080	COG0641	radical SAM
BS653_RS18095	COG3071	HemY protein
BS653_RS18100	COG2959	enzyme of heme biosynthesis
BS653_RS18105	COG1587	Uroporphyrinogen-III synthase
BS653_RS18155	COG5567	small periplasmic lipoprotein
BS653_RS18165	COG3159	Protein conserved in bacteria
BS653_RS18175	COG1011	Hydrolase
BS653_RS18180	COG0210	DNA helicase
BS653_RS18195	COG3698	Phosphodiester glycosidase
BS653_RS18200	COG0598	Magnesium transport protein CorA
BS653_RS18215	COG2962	Rard protein
BS653_RS18220	COG2050	protein possibly involved in aromatic compounds catabolism
BS653_RS18225	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BS653_RS18230	COG0514	ATP-dependent DNA helicase (RecQ)
BS653_RS18235	COG1280	lysine exporter protein (LysE YggA)
BS653_RS18240	COG1280	lysine exporter protein (LysE YggA)
BS653_RS18245	COG2267	carboxylic ester hydrolase activity
BS653_RS18250	COG0561	phosphatase activity
BS653_RS18255	COG0697	spore germination
BS653_RS18260	COG0583	DNA-binding transcription factor activity
BS653_RS18270	COG0412	Dienelactone hydrolase
BS653_RS18275	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BS653_RS18285	COG1322	Protein conserved in bacteria
BS653_RS18295	COG3165	ubiquinone biosynthetic process from chorismate
BS653_RS18305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS653_RS18310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS653_RS18315	COG0805	protein transport
BS653_RS18325	COG0250	Participates in transcription elongation, termination and antitermination
BS653_RS18335	COG0543	2 iron, 2 sulfur cluster binding
BS653_RS18355	COG1739	Uncharacterized protein family UPF0029
BS653_RS18360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS653_RS18365	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BS653_RS18395	COG1763	Mo-molybdopterin cofactor biosynthetic process
BS653_RS18400	COG0746	molybdenum cofactor guanylyltransferase activity
BS653_RS18405	COG3084	Protein conserved in bacteria
BS653_RS18420	COG5339	Protein conserved in bacteria
BS653_RS18425	COG0204	Acyl-transferase
BS653_RS18435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS653_RS18435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS653_RS18455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS653_RS18465	COG2204	response regulator
BS653_RS18470	COG3852	Histidine kinase
BS653_RS18480	COG0174	glutamine synthetase
BS653_RS18490	COG1217	gtp-binding protein TYPA
BS653_RS18495	COG2188	Transcriptional regulator
BS653_RS18500	COG1082	Xylose isomerase domain protein TIM barrel
BS653_RS18505	COG2271	Major facilitator Superfamily
BS653_RS18515	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BS653_RS18520	COG2211	Major facilitator Superfamily
BS653_RS18530	COG1501	Belongs to the glycosyl hydrolase 31 family
BS653_RS18535	COG2017	converts alpha-aldose to the beta-anomer
BS653_RS18540	COG2942	2-epimerase
BS653_RS18550	COG2084	Dehydrogenase
BS653_RS18555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS653_RS18560	COG1349	DNA-binding transcription factor activity
BS653_RS18565	COG1011	Hydrolase
BS653_RS18580	COG0456	acetyltransferase
BS653_RS18630	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BS653_RS18635	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BS653_RS18645	COG2864	formate dehydrogenase
BS653_RS18650	COG0437	4 iron, 4 sulfur cluster binding
BS653_RS18675	COG3711	transcriptional antiterminator
BS653_RS18675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS18680	COG1363	Peptidase, m42
BS653_RS18685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS18685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS18690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS18730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS653_RS18750	COG2258	MOSC domain
BS653_RS18755	COG2205	protein histidine kinase activity
BS653_RS18760	COG0745	RESPONSE REGULATOR receiver
BS653_RS18765	COG3678	ATP-independent chaperone mediated protein folding
BS653_RS18780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BS653_RS18810	COG3691	Protein conserved in bacteria
BS653_RS18815	COG0589	response to stress
BS653_RS18825	COG1494	fructose-1,6-bisphosphatase
BS653_RS18835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BS653_RS18850	COG1575	Belongs to the MenA family. Type 1 subfamily
BS653_RS18865	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BS653_RS18870	COG1609	Transcriptional regulator
BS653_RS18875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS653_RS18885	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BS653_RS18900	COG0626	cystathionine gamma-synthase activity
BS653_RS18905	COG0527	aspartate kinase activity
BS653_RS18905	COG0460	homoserine dehydrogenase
BS653_RS18910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BS653_RS18920	COG0697	spore germination
BS653_RS18945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS18950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS18955	COG1882	Formate acetyltransferase
BS653_RS18960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BS653_RS18965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS18970	COG2207	Transcriptional regulator
BS653_RS18975	COG2194	sulfuric ester hydrolase activity
BS653_RS19005	COG3385	transposase activity
BS653_RS19010	COG4948	Mandelate Racemase Muconate Lactonizing
BS653_RS19015	COG2271	Major facilitator Superfamily
BS653_RS19025	COG2271	Major facilitator Superfamily
BS653_RS19030	COG0583	DNA-binding transcription factor activity
BS653_RS19060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS653_RS19095	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BS653_RS19095	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BS653_RS19140	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS653_RS19145	COG0250	Participates in transcription elongation, termination and antitermination
BS653_RS19185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BS653_RS19195	COG2104	thiamine diphosphate biosynthetic process
BS653_RS19200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS653_RS19240	COG3068	Protein conserved in bacteria
BS653_RS19255	COG3678	ATP-independent chaperone mediated protein folding
BS653_RS19265	COG4191	Histidine kinase
BS653_RS19270	COG2204	response regulator
BS653_RS19275	COG0151	Belongs to the GarS family
BS653_RS19310	COG0456	acetyltransferase
BS653_RS19320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BS653_RS19325	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BS653_RS19330	COG2224	Isocitrate lyase
BS653_RS19345	COG1414	Transcriptional regulator
BS653_RS19350	COG1410	methionine synthase
BS653_RS19350	COG0646	methionine synthase
BS653_RS19355	COG1283	sodium-dependent phosphate transmembrane transporter activity
BS653_RS19415	COG3592	Divergent 4Fe-4S mono-cluster
BS653_RS19435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BS653_RS19440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BS653_RS19440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BS653_RS19445	COG3647	Membrane
BS653_RS19450	COG2211	Major facilitator Superfamily
BS653_RS19455	COG1486	melibiose metabolic process
BS653_RS19460	COG2169	Transcriptional regulator
BS653_RS19465	COG1982	Orn Lys Arg decarboxylase major
BS653_RS19470	COG2207	Transcriptional regulator
BS653_RS19475	COG0531	amino acid
BS653_RS19480	COG2194	sulfuric ester hydrolase activity
BS653_RS19485	COG0745	RESPONSE REGULATOR receiver
BS653_RS19490	COG0642	Histidine kinase
BS653_RS19500	COG0477	Major facilitator Superfamily
BS653_RS19510	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS653_RS19520	COG2824	Alkylphosphonate utilization operon protein PhnA
BS653_RS19525	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BS653_RS19535	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BS653_RS19540	COG3639	organic phosphonate transmembrane transporter activity
BS653_RS19555	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BS653_RS19565	COG2207	Transcriptional regulator
BS653_RS19570	COG0789	Transcriptional regulator
BS653_RS19585	COG2252	PERMEase
BS653_RS19590	COG0025	NhaP-type Na H and K H
BS653_RS19595	COG1357	PFAM Pentapeptide repeats (8 copies)
BS653_RS19605	COG3162	membrane
BS653_RS19625	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BS653_RS19630	COG0437	4 iron, 4 sulfur cluster binding
BS653_RS19635	COG3301	Polysulphide reductase, NrfD
BS653_RS19640	COG1138	Cytochrome C-type biogenesis protein
BS653_RS19645	COG3088	subunit of a heme lyase
BS653_RS19650	COG4235	cytochrome complex assembly
BS653_RS19660	COG1301	dicarboxylic acid transport
BS653_RS19665	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BS653_RS19705	COG0629	single-stranded DNA binding
BS653_RS19710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BS653_RS19715	COG2315	Protein conserved in bacteria
BS653_RS19720	COG0432	Pfam Uncharacterised protein family UPF0047
BS653_RS19725	COG3700	Belongs to the class B bacterial acid phosphatase family
BS653_RS19735	COG1448	Aminotransferase
BS653_RS19740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS653_RS19745	COG0305	Participates in initiation and elongation during chromosome replication
BS653_RS19750	COG0604	alcohol dehydrogenase
BS653_RS19760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS653_RS19775	COG0735	belongs to the Fur family
BS653_RS19780	COG3237	CsbD-like
BS653_RS19785	COG0534	Mate efflux family protein
BS653_RS19795	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BS653_RS19845	COG2182	Extracellular solute-binding protein
BS653_RS19850	COG1175	transmembrane transport
BS653_RS19855	COG3833	ABC-type maltose transport systems, permease component
BS653_RS19860	COG0477	Major facilitator Superfamily
BS653_RS19860	COG2814	Major facilitator Superfamily
BS653_RS19875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BS653_RS19910	COG0527	aspartate kinase activity
BS653_RS19915	COG4372	Transposase
BS653_RS19920	COG3436	PFAM IS66 Orf2 family protein
BS653_RS19945	COG3366	ferrous iron transmembrane transporter activity
BS653_RS19950	COG0700	Nucleoside recognition
BS653_RS19955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS653_RS19960	COG0583	DNA-binding transcription factor activity
BS653_RS19985	COG2186	Transcriptional regulator
BS653_RS19995	COG0246	Mannitol dehydrogenase
BS653_RS20010	COG2610	gluconate transmembrane transporter activity
BS653_RS20015	COG3539	Fimbrial protein
BS653_RS20020	COG3539	Fimbrial protein
BS653_RS20025	COG3539	Fimbrial protein
BS653_RS20030	COG3188	usher protein
BS653_RS20040	COG3188	usher protein
BS653_RS20045	COG3121	Chaperone
BS653_RS20050	COG3539	Fimbrial protein
BS653_RS20060	COG4974	Belongs to the 'phage' integrase family
BS653_RS20065	COG0582	viral genome integration into host DNA
BS653_RS20080	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BS653_RS20105	COG1349	DNA-binding transcription factor activity
BS653_RS20110	COG0440	acetolactate synthase activity
BS653_RS20125	COG2801	Transposase and inactivated derivatives
BS653_RS20155	COG0582	viral genome integration into host DNA
BS653_RS20165	COG1064	alcohol dehydrogenase
BS653_RS20170	COG0433	COG0433 Predicted ATPase
BS653_RS20175	COG0795	lipopolysaccharide-transporting ATPase activity
BS653_RS20180	COG0795	lipopolysaccharide-transporting ATPase activity
BS653_RS20190	COG2927	DNA polymerase III (CHI subunit)
BS653_RS20200	COG4269	membrane
BS653_RS20205	COG0456	acetyltransferase
BS653_RS20210	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BS653_RS20230	COG2731	YhcH YjgK YiaL family protein
BS653_RS20235	COG1309	transcriptional regulator
BS653_RS20240	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS20245	COG0251	oxidation-reduction process
BS653_RS20270	COG0251	oxidation-reduction process
BS653_RS20275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS653_RS20280	COG1609	Transcriptional regulator
BS653_RS20285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS653_RS20285	COG1263	PTS System
BS653_RS20290	COG0366	Alpha amylase catalytic
BS653_RS20295	COG1328	CTP reductase activity
BS653_RS20300	COG0602	queuosine metabolic process
BS653_RS20310	COG0312	modulator of DNA gyrase
BS653_RS20320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BS653_RS20335	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS653_RS20340	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS653_RS20345	COG1129	ABC transporter
BS653_RS20355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BS653_RS20365	COG2105	PFAM AIG2 family protein
BS653_RS20370	COG2911	Protein conserved in bacteria
BS653_RS20375	COG0729	surface antigen
BS653_RS20390	COG1253	flavin adenine dinucleotide binding
BS653_RS20400	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BS653_RS20415	COG0737	Belongs to the 5'-nucleotidase family
BS653_RS20420	COG1733	regulation of RNA biosynthetic process
BS653_RS20425	COG0702	epimerase
BS653_RS20430	COG0697	spore germination
BS653_RS20440	COG1113	amino acid transport
BS653_RS20445	COG0545	Peptidyl-prolyl cis-trans isomerase
BS653_RS20455	COG3061	Opacity-associated protein A
BS653_RS20460	COG1309	transcriptional regulator
BS653_RS20485	COG0531	amino acid
BS653_RS20510	COG1309	transcriptional regulator
BS653_RS20525	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BS653_RS20530	COG1027	Aspartate ammonia-lyase
BS653_RS20535	COG3030	protein affecting phage T7 exclusion by the F plasmid
BS653_RS20540	COG0531	amino acid
BS653_RS20575	COG1509	lysine 2,3-aminomutase activity
BS653_RS20585	COG5510	response to toxic substance
BS653_RS20590	COG5510	response to toxic substance
BS653_RS20595	COG2076	Multidrug Resistance protein
BS653_RS20600	COG3040	lipid binding
BS653_RS20605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS653_RS20620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BS653_RS20625	COG1053	succinate dehydrogenase
BS653_RS20635	COG0531	amino acid
BS653_RS20650	COG3264	Mechanosensitive ion channel
BS653_RS20650	COG1511	domain protein
BS653_RS20695	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BS653_RS20700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BS653_RS20700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BS653_RS20705	COG0802	atpase or kinase
BS653_RS20710	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS653_RS20730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BS653_RS20735	COG0330	HflC and HflK could
BS653_RS20740	COG0330	HflC and HflK could
BS653_RS20745	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BS653_RS20765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS653_RS20775	COG3766	membrane
BS653_RS20780	COG5463	Belongs to the UPF0441 family
BS653_RS20785	COG0754	glutathionylspermidine amidase activity
BS653_RS20790	COG1960	acyl-CoA dehydrogenase activity
BS653_RS20805	COG1960	acyl-CoA dehydrogenase activity
BS653_RS20820	COG3650	response to hydrogen peroxide
BS653_RS20825	COG1073	alpha beta
BS653_RS20885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BS653_RS20920	COG0732	type I restriction modification DNA specificity domain
BS653_RS20945	COG0523	cobalamin synthesis protein
BS653_RS20950	COG2879	small protein
BS653_RS20955	COG1966	Carbon starvation protein
BS653_RS20965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS653_RS20970	COG2368	4-hydroxyphenylacetate
BS653_RS20975	COG2368	4-hydroxyphenylacetate
BS653_RS21000	COG3971	2-oxopent-4-enoate hydratase activity
BS653_RS21010	COG3384	dioxygenase
BS653_RS21015	COG1012	belongs to the aldehyde dehydrogenase family
BS653_RS21020	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS653_RS21025	COG1846	Transcriptional regulator
BS653_RS21030	COG0840	transmembrane signaling receptor activity
BS653_RS21035	COG2271	Major facilitator Superfamily
BS653_RS21040	COG1802	Transcriptional regulator
BS653_RS21060	COG1484	DNA-dependent DNA replication
BS653_RS21075	COG2966	Psort location CytoplasmicMembrane, score
BS653_RS21085	COG2197	response regulator
BS653_RS21090	COG2197	response regulator
BS653_RS21095	COG4114	ferric iron reductase
BS653_RS21125	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BS653_RS21130	COG0456	acetyltransferase
BS653_RS21135	COG1011	Hydrolase
BS653_RS21155	COG4667	esterase of the alpha-beta hydrolase superfamily
BS653_RS21160	COG0084	hydrolase, TatD family'
BS653_RS21165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BS653_RS21170	COG1328	CTP reductase activity
BS653_RS21205	COG3726	membrane protein affecting hemolysin expression
BS653_RS21210	COG0560	Phosphoserine phosphatase
BS653_RS21215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BS653_RS21220	COG3172	ATPase kinase involved in NAD metabolism
BS653_RS21220	COG1056	cytidyltransferase-related domain
BS653_RS21225	COG0488	(ABC) transporter
BS653_RS21235	COG0741	lytic transglycosylase activity
BS653_RS21255	COG3708	Transcriptional regulator
BS653_RS21255	COG2207	Transcriptional regulator
BS653_RS21260	COG3045	CreA protein
BS653_RS21265	COG0745	RESPONSE REGULATOR receiver
BS653_RS21270	COG2205	protein histidine kinase activity
BS653_RS21275	COG4452	Inner membrane protein CreD
BS653_RS21280	COG0745	RESPONSE REGULATOR receiver
BS653_RS21290	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BS653_RS21300	COG0527	aspartate kinase activity
BS653_RS21300	COG0460	homoserine dehydrogenase
BS653_RS21310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BS653_RS21330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BS653_RS21335	COG0521	Mo-molybdopterin cofactor biosynthetic process
BS653_RS21340	COG1584	GPR1 FUN34 yaaH family protein
BS653_RS21345	COG4735	regulation of single-species biofilm formation
BS653_RS21375	COG0583	DNA-binding transcription factor activity
BS653_RS21400	COG0196	riboflavin kinase activity
BS653_RS21415	COG1047	Peptidyl-prolyl cis-trans
BS653_RS21435	COG0505	Belongs to the CarA family
BS653_RS21440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BS653_RS21505	COG2271	Major facilitator Superfamily
BS653_RS21525	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS653_RS21550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS653_RS21560	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BS653_RS21565	COG0564	pseudouridine synthase activity
BS653_RS21575	COG0417	DNA replication proofreading
BS653_RS21580	COG0235	Class ii aldolase
BS653_RS21600	COG4977	sequence-specific DNA binding
BS653_RS21605	COG0586	Pfam SNARE associated Golgi protein
BS653_RS21615	COG1178	ABC-type Fe3 transport system permease component
BS653_RS21620	COG4143	(ABC) transporter
BS653_RS21635	COG2814	Major facilitator Superfamily
BS653_RS21665	COG0583	DNA-binding transcription factor activity
BS653_RS21670	COG0028	Belongs to the TPP enzyme family
BS653_RS21675	COG0440	acetolactate synthase activity
BS653_RS21685	COG1609	Transcriptional regulator
BS653_RS21710	COG3116	cell division
BS653_RS21715	COG0768	penicillin binding
BS653_RS21725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BS653_RS21740	COG0772	Belongs to the SEDS family
BS653_RS21760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BS653_RS21765	COG0849	cell division
BS653_RS21770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BS653_RS21790	COG0494	nUDIX hydrolase
BS653_RS21815	COG1459	type II secretion system
BS653_RS21825	COG4969	Belongs to the N-Me-Phe pilin family
BS653_RS21835	COG0157	Belongs to the NadC ModD family
BS653_RS21840	COG3023	N-Acetylmuramoyl-L-alanine amidase
BS653_RS21845	COG3725	Membrane protein required for beta-lactamase induction
BS653_RS21855	COG2186	Transcriptional regulator
BS653_RS21865	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BS653_RS21870	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS653_RS21875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS653_RS21890	COG3064	Membrane
BS653_RS21900	COG1049	propionate catabolic process, 2-methylcitrate cycle
BS653_RS21925	COG2132	Multicopper oxidase
BS653_RS21930	COG4993	Dehydrogenase
BS653_RS21935	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BS653_RS21940	COG0288	reversible hydration of carbon dioxide
BS653_RS21945	COG1131	(ABC) transporter
BS653_RS21950	COG0842	Transport permease protein
BS653_RS21955	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS21960	COG0726	polysaccharide deacetylase
BS653_RS21975	COG5464	transposase or invertase
BS653_RS21990	COG3539	Fimbrial protein
BS653_RS22000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BS653_RS22005	COG0617	tRNA 3'-terminal CCA addition
BS653_RS22015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS653_RS22025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BS653_RS22030	COG1643	Atp-dependent helicase
BS653_RS22040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS653_RS22045	COG4774	siderophore transport
BS653_RS22050	COG1120	ATPase activity
BS653_RS22055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS653_RS22060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS653_RS22080	COG2860	membrane
BS653_RS22105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS653_RS22130	COG0024	Methionine aminopeptidase
BS653_RS22170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BS653_RS22175	COG0575	Belongs to the CDS family
BS653_RS22180	COG0750	zinc metalloprotease
BS653_RS22190	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BS653_RS22195	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BS653_RS22220	COG0587	DNA-directed DNA polymerase activity
BS653_RS22230	COG1982	Orn Lys Arg decarboxylase major
BS653_RS22235	COG0346	lactoylglutathione lyase activity
BS653_RS22245	COG4568	rho-dependent transcription termination
BS653_RS22255	COG4681	YaeQ
BS653_RS22260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BS653_RS22265	COG3015	lipoprotein NlpE involved in copper resistance
BS653_RS22270	COG0791	NLP P60 protein
BS653_RS22280	COG1720	tRNA m6t6A37 methyltransferase activity
BS653_RS22290	COG1464	Belongs to the NlpA lipoprotein family
BS653_RS22295	COG2011	ABC-type metal ion transport system permease component
BS653_RS22300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS653_RS22305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BS653_RS22340	COG0656	L-ascorbic acid biosynthetic process
BS653_RS22350	COG0583	DNA-binding transcription factor activity
BS653_RS22360	COG2226	methyltransferase
BS653_RS22365	COG0741	lytic transglycosylase activity
BS653_RS22365	COG1388	LysM domain
BS653_RS22375	COG2226	methyltransferase
BS653_RS22385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS653_RS22530	COG1181	Belongs to the D-alanine--D-alanine ligase family
BS653_RS22550	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BS653_RS22560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS653_RS22565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS653_RS22570	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS22585	COG2963	transposase activity
BS653_RS22590	COG3468	outer membrane autotransporter barrel domain protein
BS653_RS22615	COG0113	porphobilinogen synthase activity
BS653_RS22620	COG2175	clavaminate synthase activity
BS653_RS22625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS653_RS22635	COG4521	taurine ABC transporter
BS653_RS22665	COG1556	Lactate utilization protein
BS653_RS22670	COG1139	Iron-sulfur cluster binding protein
BS653_RS22675	COG0247	lactate metabolic process
BS653_RS22735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS653_RS22745	COG1960	acyl-CoA dehydrogenase activity
BS653_RS22755	COG0121	glutamine amidotransferase
BS653_RS22760	COG3034	peptidoglycan biosynthetic process
BS653_RS22770	COG1943	Transposase
BS653_RS22790	COG2161	toxin-antitoxin pair type II binding
BS653_RS22800	COG0454	-acetyltransferase
BS653_RS22820	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS653_RS22840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BS653_RS22865	COG0582	viral genome integration into host DNA
BS653_RS22910	COG3723	Recombinational DNA repair protein, rece pathway
BS653_RS22955	COG0305	Participates in initiation and elongation during chromosome replication
BS653_RS23145	COG2246	polysaccharide biosynthetic process
BS653_RS23150	COG0582	viral genome integration into host DNA
BS653_RS23170	COG3706	GGDEF domain
BS653_RS23175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS653_RS23200	COG4126	flavin adenine dinucleotide binding
BS653_RS23230	COG1940	carbohydrate kinase activity
BS653_RS23235	COG2814	Major facilitator Superfamily
BS653_RS23240	COG0419	ATPase involved in DNA repair
BS653_RS23245	COG0420	3'-5' exonuclease activity
BS653_RS23255	COG5002	protein histidine kinase activity
BS653_RS23260	COG1114	Component of the transport system for branched-chain amino acids
BS653_RS23265	COG1113	amino acid transport
BS653_RS23270	COG0366	Alpha amylase catalytic
BS653_RS23290	COG1862	Preprotein translocase
BS653_RS23295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS653_RS23300	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS653_RS23305	COG1403	HNH endonuclease
BS653_RS23310	COG3248	Nucleoside-binding outer membrane protein
BS653_RS23315	COG4238	major outer membrane lipoprotein
BS653_RS23325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS653_RS23325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS653_RS23340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BS653_RS23345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS653_RS23350	COG0667	Aldo Keto reductase
BS653_RS23360	COG0142	geranyltranstransferase activity
BS653_RS23375	COG0693	protein deglycase activity
BS653_RS23380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS653_RS23425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BS653_RS23430	COG1845	cytochrome c oxidase, subunit III
BS653_RS23440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS653_RS23445	COG4372	Transposase
BS653_RS23450	COG3436	PFAM IS66 Orf2 family protein
BS653_RS23465	COG2223	nitrite transmembrane transporter activity
BS653_RS23470	COG3056	Lipoprotein
BS653_RS23475	COG0271	Belongs to the BolA IbaG family
BS653_RS23500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BS653_RS23505	COG0776	regulation of translation
BS653_RS23510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS653_RS23515	COG1555	photosystem II stabilization
BS653_RS23520	COG0824	Thioesterase
BS653_RS23530	COG4533	DNA binding
BS653_RS23540	COG1522	sequence-specific DNA binding
BS653_RS23545	COG1132	(ABC) transporter
BS653_RS23550	COG1132	(ABC) transporter
BS653_RS23555	COG0347	Belongs to the P(II) protein family
BS653_RS23560	COG0004	ammonium transporteR
BS653_RS23565	COG1946	Acyl-CoA thioesterase
BS653_RS23570	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BS653_RS23580	COG3695	enzyme binding
BS653_RS23590	COG5507	3-demethylubiquinone-9 3-methyltransferase
BS653_RS23595	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BS653_RS23620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS653_RS23625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS653_RS23630	COG1309	transcriptional regulator
BS653_RS23640	COG1196	nuclear chromosome segregation
BS653_RS23640	COG3264	Mechanosensitive ion channel
BS653_RS23650	COG3923	Primosomal replication protein n
BS653_RS23655	COG2832	Protein of unknown function (DUF454)
BS653_RS23670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BS653_RS23710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS653_RS23715	COG4651	solute:proton antiporter activity
BS653_RS23715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BS653_RS23720	COG2223	nitrite transmembrane transporter activity
BS653_RS23730	COG0737	Belongs to the 5'-nucleotidase family
BS653_RS23735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BS653_RS23745	COG3735	TraB family
BS653_RS23750	COG3093	addiction module antidote protein HigA
BS653_RS23755	COG2217	Heavy metal translocating P-type atpase
BS653_RS23765	COG0531	amino acid
BS653_RS23770	COG0789	Transcriptional regulator
BS653_RS23775	COG1585	Membrane protein implicated in regulation of membrane protease activity
BS653_RS23780	COG0330	HflC and HflK could
BS653_RS23785	COG4619	ABC transporter
BS653_RS23790	COG0390	transport system, permease component
BS653_RS23795	COG3118	belongs to the thioredoxin family
BS653_RS23800	COG0300	oxidoreductase activity
BS653_RS23810	COG4181	ATPase activity
BS653_RS23830	COG0583	DNA-binding transcription factor activity
BS653_RS23840	COG1414	Transcriptional regulator
BS653_RS23845	COG3960	tartronate-semialdehyde synthase activity
BS653_RS23850	COG3622	Belongs to the hyi family
BS653_RS23865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS653_RS23875	COG0549	Belongs to the carbamate kinase family
BS653_RS23880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BS653_RS23885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BS653_RS23900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS653_RS23910	COG1988	membrane-bound metal-dependent
BS653_RS23915	COG2501	S4 domain
BS653_RS23925	COG3539	Fimbrial protein
BS653_RS23930	COG3121	Chaperone
BS653_RS23935	COG3188	usher protein
BS653_RS23945	COG2197	response regulator
BS653_RS23960	COG2207	Transcriptional regulator
BS653_RS23980	COG4783	chaperone-mediated protein folding
BS653_RS23985	COG1215	transferase activity, transferring glycosyl groups
BS653_RS23990	COG5002	protein histidine kinase activity
BS653_RS23995	COG0745	RESPONSE REGULATOR receiver
BS653_RS24005	COG1538	Outer membrane efflux protein
BS653_RS24010	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS653_RS24015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS653_RS24020	COG0582	viral genome integration into host DNA
BS653_RS24045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS653_RS24050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS653_RS24055	COG1113	amino acid transport
BS653_RS24060	COG0668	transmembrane transport
BS653_RS24065	COG0778	Nitroreductase
BS653_RS24070	COG2315	Protein conserved in bacteria
BS653_RS24130	COG2977	Belongs to the P-Pant transferase superfamily
BS653_RS24135	COG4771	TonB-dependent receptor
BS653_RS24140	COG2382	esterase
BS653_RS24145	COG3251	PFAM MbtH domain protein
BS653_RS24160	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BS653_RS24165	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BS653_RS24170	COG1120	ATPase activity
BS653_RS24175	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS653_RS24180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS653_RS24190	COG4592	Periplasmic binding protein
BS653_RS24200	COG1021	2,3-dihydroxybenzoate-AMP ligase
BS653_RS24205	COG3433	isochorismatase activity
BS653_RS24205	COG1535	isochorismatase
BS653_RS24210	COG1028	Short-chain dehydrogenase reductase Sdr
BS653_RS24220	COG1966	Carbon starvation protein
BS653_RS24225	COG2879	small protein
BS653_RS24230	COG0371	Dehydrogenase
BS653_RS24235	COG0436	Aminotransferase
BS653_RS24240	COG1475	DNA binding
BS653_RS24255	COG1475	DNA binding
BS653_RS24275	COG0583	DNA-binding transcription factor activity
BS653_RS24280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BS653_RS24285	COG0450	alkyl hydroperoxide reductase
BS653_RS24290	COG3634	alkyl hydroperoxide reductase activity
BS653_RS24300	COG1063	alcohol dehydrogenase
BS653_RS24310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS653_RS24320	COG3719	Belongs to the RNase T2 family
BS653_RS24340	COG3051	citrate lyase alpha subunit
BS653_RS24345	COG2301	Belongs to the HpcH HpaI aldolase family
BS653_RS24355	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BS653_RS24360	COG3290	protein histidine kinase activity
BS653_RS24370	COG0582	viral genome integration into host DNA
BS653_RS24375	COG0561	phosphatase activity
BS653_RS24385	COG4149	molybdate abc transporter
BS653_RS24390	COG0725	ABC transporter, periplasmic molybdate-binding protein
BS653_RS24405	COG2005	Transcriptional regulator
BS653_RS24405	COG3585	molybdate ion transport
BS653_RS24410	COG1119	ATPase activity
BS653_RS24415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BS653_RS24420	COG1085	galactose-1-phosphate uridylyltransferase
BS653_RS24430	COG2017	converts alpha-aldose to the beta-anomer
BS653_RS24440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BS653_RS24460	COG3201	nicotinamide mononucleotide transporter
BS653_RS24495	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BS653_RS24500	COG2885	chlorophyll binding
BS653_RS24510	COG3064	Membrane
BS653_RS24515	COG0848	biopolymer transport protein
BS653_RS24520	COG0811	peptide transport
BS653_RS24525	COG0824	Thioesterase
BS653_RS24530	COG3790	cyd operon protein YbgE
BS653_RS24535	COG4890	Cyd operon protein YbgT
BS653_RS24540	COG1294	oxidase, subunit
BS653_RS24545	COG1271	oxidase subunit
BS653_RS24555	COG0383	alpha-mannosidase activity
BS653_RS24560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS653_RS24560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS24560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS653_RS24565	COG2188	Transcriptional regulator
BS653_RS24570	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BS653_RS24580	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS653_RS24585	COG0567	Dehydrogenase, E1 component
BS653_RS24590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BS653_RS24595	COG1053	succinate dehydrogenase
BS653_RS24600	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BS653_RS24605	COG2009	succinate dehydrogenase
BS653_RS24620	COG0372	Belongs to the citrate synthase family
BS653_RS24625	COG3539	Fimbrial protein
BS653_RS24630	COG3188	usher protein
BS653_RS24635	COG3121	Chaperone
BS653_RS24645	COG3180	Ammonia monooxygenase
BS653_RS24665	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BS653_RS24670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BS653_RS24680	COG0415	Belongs to the DNA photolyase family
BS653_RS24685	COG3272	Protein of unknown function (DUF1722)
BS653_RS24700	COG3209	COG3209 Rhs family protein
BS653_RS24760	COG0531	amino acid
BS653_RS24765	COG0033	Phosphoglucomutase
BS653_RS24770	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BS653_RS24775	COG0596	Alpha beta hydrolase
BS653_RS24785	COG0716	FMN binding
BS653_RS24795	COG0735	belongs to the Fur family
BS653_RS24815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS653_RS24815	COG1263	PTS System
BS653_RS24815	COG2190	(PTS) system
BS653_RS24825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS653_RS24830	COG1940	carbohydrate kinase activity
BS653_RS24830	COG1846	Transcriptional regulator
BS653_RS24845	COG0367	asparagine synthase
BS653_RS24890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS653_RS24900	COG1702	phosphate starvation-inducible protein PhoH
BS653_RS24910	COG4535	Mg2 and Co2 transporter CorC
BS653_RS24920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS653_RS24925	COG0765	amino acid transport
BS653_RS24930	COG0765	amino acid transport
BS653_RS24935	COG1126	abc transporter atp-binding protein
BS653_RS24950	COG2214	Heat shock protein DnaJ domain protein
BS653_RS24960	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BS653_RS24965	COG2214	Heat shock protein DnaJ domain protein
BS653_RS24975	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BS653_RS24980	COG2888	peptidyl-tyrosine sulfation
BS653_RS24995	COG1466	dna polymerase III delta subunit
BS653_RS25005	COG0406	alpha-ribazole phosphatase activity
BS653_RS25010	COG0799	negative regulation of ribosome biogenesis
BS653_RS25020	COG0768	penicillin binding
BS653_RS25025	COG0772	Belongs to the SEDS family
BS653_RS25030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BS653_RS25035	COG1686	Belongs to the peptidase S11 family
BS653_RS25055	COG0583	DNA-binding transcription factor activity
BS653_RS25070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS653_RS25075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS653_RS25105	COG3069	C4-dicarboxylate transmembrane transporter activity
BS653_RS25120	COG3423	Transcriptional regulator
BS653_RS25125	COG2801	Transposase and inactivated derivatives
BS653_RS25805	COG0250	Participates in transcription elongation, termination and antitermination
BS653_RS25855	COG2026	Addiction module toxin, RelE StbE family
BS653_RS25895	COG1192	Involved in chromosome partitioning
BS653_RS25995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS653_RS26015	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis