locus-tag	class	description
FOB99_RS00010	COG0195	Participates in both transcription termination and antitermination
FOB99_RS00040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB99_RS00050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOB99_RS00055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB99_RS00065	COG1534	Rna-binding protein
FOB99_RS00070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB99_RS00075	COG2027	D-alanyl-D-alanine carboxypeptidase
FOB99_RS00085	COG0697	spore germination
FOB99_RS00100	COG0142	geranyltranstransferase activity
FOB99_RS00105	COG3423	Transcriptional regulator
FOB99_RS00115	COG5007	Belongs to the BolA IbaG family
FOB99_RS00120	COG3113	response to antibiotic
FOB99_RS00125	COG2854	intermembrane phospholipid transfer
FOB99_RS00130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB99_RS00135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOB99_RS00140	COG1127	ABC transporter
FOB99_RS00145	COG0530	calcium, potassium:sodium antiporter activity
FOB99_RS00155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOB99_RS00160	COG3117	lipopolysaccharide transmembrane transporter activity
FOB99_RS00165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOB99_RS00170	COG1137	ATPase activity
FOB99_RS00175	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOB99_RS00180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB99_RS00195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS00200	COG0515	serine threonine protein kinase
FOB99_RS00210	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FOB99_RS00215	COG5002	protein histidine kinase activity
FOB99_RS00215	COG2198	Histidine kinase
FOB99_RS00215	COG0784	Response regulator, receiver
FOB99_RS00220	COG1242	4 iron, 4 sulfur cluster binding
FOB99_RS00225	COG0069	glutamate synthase activity
FOB99_RS00225	COG0067	glutamate synthase
FOB99_RS00225	COG0070	glutamate synthase
FOB99_RS00230	COG0493	'glutamate synthase
FOB99_RS00235	COG4804	nuclease activity
FOB99_RS00245	COG2731	YhcH YjgK YiaL family protein
FOB99_RS00280	COG3069	C4-dicarboxylate transmembrane transporter activity
FOB99_RS00285	COG2969	positive regulation of protein catabolic process
FOB99_RS00290	COG0625	glutathione transferase activity
FOB99_RS00305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOB99_RS00310	COG3105	Protein conserved in bacteria
FOB99_RS00320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB99_RS00340	COG2732	(Barnase) inhibitor
FOB99_RS00360	COG0583	DNA-binding transcription factor activity
FOB99_RS00365	COG0312	modulator of DNA gyrase
FOB99_RS00370	COG3164	Protein of unknown function
FOB99_RS00375	COG1530	ribonuclease E activity
FOB99_RS00385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOB99_RS00390	COG1792	Involved in formation and maintenance of cell shape
FOB99_RS00395	COG1077	Cell shape determining protein MreB Mrl
FOB99_RS00400	COG2200	EAL domain
FOB99_RS00400	COG2199	diguanylate cyclase activity
FOB99_RS00405	COG0604	alcohol dehydrogenase
FOB99_RS00410	COG0511	ligase activity, forming carbon-carbon bonds
FOB99_RS00415	COG0439	Biotin carboxylase
FOB99_RS00420	COG3924	membrane
FOB99_RS00425	COG4145	pantothenate transmembrane transporter activity
FOB99_RS00445	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FOB99_RS00460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB99_RS00475	COG4597	amino acid ABC transporter
FOB99_RS00480	COG0765	amino acid transport
FOB99_RS00485	COG1126	abc transporter atp-binding protein
FOB99_RS00525	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOB99_RS00545	COG0551	DNA topoisomerase type I activity
FOB99_RS00555	COG0758	DNA mediated transformation
FOB99_RS00575	COG0569	domain protein
FOB99_RS00585	COG3436	PFAM IS66 Orf2 family protein
FOB99_RS00590	COG4372	Transposase
FOB99_RS00630	COG0201	protein transport
FOB99_RS00720	COG0089	rRNA binding
FOB99_RS00790	COG2964	Protein conserved in bacteria
FOB99_RS00795	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB99_RS00805	COG1047	Peptidyl-prolyl cis-trans
FOB99_RS00810	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FOB99_RS00825	COG0488	(ABC) transporter
FOB99_RS00830	COG0429	hydrolase of the alpha beta-hydrolase fold
FOB99_RS00840	COG3954	Phosphoribulokinase
FOB99_RS00845	COG1765	OsmC-like protein
FOB99_RS00850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB99_RS00855	COG1289	transmembrane transporter activity
FOB99_RS00865	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB99_RS00870	COG2184	nucleotidyltransferase activity
FOB99_RS00880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB99_RS00890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB99_RS00895	COG2146	nitrite reductase [NAD(P)H] activity
FOB99_RS00900	COG2116	formate transmembrane transporter activity
FOB99_RS00920	COG2222	sugar isomerase
FOB99_RS00940	COG0626	cystathionine gamma-synthase activity
FOB99_RS00955	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FOB99_RS00960	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOB99_RS00965	COG3457	Alanine racemase
FOB99_RS00975	COG2188	Transcriptional regulator
FOB99_RS00990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB99_RS00995	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOB99_RS01000	COG3266	domain, Protein
FOB99_RS01015	COG4796	Type ii and iii secretion system protein
FOB99_RS01030	COG3166	PFAM Fimbrial assembly family protein
FOB99_RS01035	COG4972	Pilus assembly protein
FOB99_RS01040	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOB99_RS01045	COG0494	nUDIX hydrolase
FOB99_RS01055	COG1011	Hydrolase
FOB99_RS01060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOB99_RS01070	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOB99_RS01080	COG2205	protein histidine kinase activity
FOB99_RS01085	COG0745	RESPONSE REGULATOR receiver
FOB99_RS01090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB99_RS01095	COG2183	response to ionizing radiation
FOB99_RS01100	COG1918	ferrous iron import across plasma membrane
FOB99_RS01115	COG5464	transposase or invertase
FOB99_RS01150	COG2610	gluconate transmembrane transporter activity
FOB99_RS01155	COG1640	4-alpha-glucanotransferase
FOB99_RS01160	COG0058	SHG alpha-glucan phosphorylase activity
FOB99_RS01175	COG1690	Belongs to the RtcB family
FOB99_RS01180	COG4650	regulator
FOB99_RS01185	COG1349	DNA-binding transcription factor activity
FOB99_RS01200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOB99_RS01210	COG3385	transposase activity
FOB99_RS01215	COG0058	SHG alpha-glucan phosphorylase activity
FOB99_RS01240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB99_RS01245	COG2095	MarC family integral membrane protein
FOB99_RS01250	COG2610	gluconate transmembrane transporter activity
FOB99_RS01255	COG3265	gluconokinase activity
FOB99_RS01260	COG1609	Transcriptional regulator
FOB99_RS01265	COG1741	Belongs to the pirin family
FOB99_RS01270	COG0673	inositol 2-dehydrogenase activity
FOB99_RS01275	COG1247	-acetyltransferase
FOB99_RS01280	COG0405	Gamma-glutamyltransferase
FOB99_RS01290	COG0584	glycerophosphoryl diester phosphodiesterase
FOB99_RS01315	COG0410	ABC transporter
FOB99_RS01320	COG0411	ABC transporter
FOB99_RS01325	COG4177	L-phenylalanine transmembrane transporter activity
FOB99_RS01330	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB99_RS01335	COG0683	leucine binding
FOB99_RS01340	COG0456	acetyltransferase
FOB99_RS01345	COG0683	leucine binding
FOB99_RS01350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB99_RS01355	COG2177	Part of the ABC transporter FtsEX involved in
FOB99_RS01360	COG2884	Cell division ATP-binding protein ftsE
FOB99_RS01365	COG0552	protein localization to endoplasmic reticulum
FOB99_RS01370	COG0742	ribosomal rna small subunit methyltransferase
FOB99_RS01375	COG3776	membrane
FOB99_RS01385	COG3714	YhhN family
FOB99_RS01400	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOB99_RS01415	COG0628	permease
FOB99_RS01420	COG2091	lysine biosynthetic process via aminoadipic acid
FOB99_RS01425	COG0747	negative chemotaxis
FOB99_RS01430	COG0601	transmembrane transport
FOB99_RS01435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB99_RS01465	COG0842	Transport permease protein
FOB99_RS01470	COG0842	Transport permease protein
FOB99_RS01470	COG1129	ABC transporter
FOB99_RS01475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB99_RS01560	COG2081	HI0933 family
FOB99_RS01565	COG0306	phosphate transporter
FOB99_RS01575	COG0589	response to stress
FOB99_RS01590	COG0339	signal peptide processing
FOB99_RS01595	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOB99_RS01600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB99_RS01615	COG1393	Belongs to the ArsC family
FOB99_RS01625	COG0640	Transcriptional regulator
FOB99_RS01645	COG3065	identical protein binding
FOB99_RS01670	COG3247	response to pH
FOB99_RS01675	COG2771	luxR family
FOB99_RS01700	COG3385	transposase activity
FOB99_RS01705	COG2197	response regulator
FOB99_RS01710	COG0583	DNA-binding transcription factor activity
FOB99_RS01715	COG1295	ribonuclease BN
FOB99_RS01720	COG0477	Major facilitator Superfamily
FOB99_RS01725	COG2982	Protein involved in outer membrane biogenesis
FOB99_RS01730	COG2200	EAL domain
FOB99_RS01740	COG0612	Peptidase, M16
FOB99_RS01750	COG2199	diguanylate cyclase activity
FOB99_RS01750	COG2200	EAL domain
FOB99_RS01760	COG3118	belongs to the thioredoxin family
FOB99_RS01760	COG0457	Tetratricopeptide repeat
FOB99_RS01765	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOB99_RS01770	COG1215	transferase activity, transferring glycosyl groups
FOB99_RS01780	COG1215	transferase activity, transferring glycosyl groups
FOB99_RS01805	COG2194	sulfuric ester hydrolase activity
FOB99_RS01830	COG0814	amino acid
FOB99_RS01835	COG4608	Belongs to the ABC transporter superfamily
FOB99_RS01840	COG0444	Belongs to the ABC transporter superfamily
FOB99_RS01845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB99_RS01850	COG0601	transmembrane transport
FOB99_RS01855	COG0747	negative chemotaxis
FOB99_RS01865	COG2194	sulfuric ester hydrolase activity
FOB99_RS01870	COG2223	nitrite transmembrane transporter activity
FOB99_RS01875	COG5571	outer membrane autotransporter
FOB99_RS01880	COG2818	Glycosylase
FOB99_RS01885	COG0456	acetyltransferase
FOB99_RS01890	COG0243	molybdopterin cofactor binding
FOB99_RS01895	COG2885	chlorophyll binding
FOB99_RS01915	COG1278	Cold shock
FOB99_RS01935	COG1858	cytochrome C peroxidase
FOB99_RS01950	COG2207	Transcriptional regulator
FOB99_RS01985	COG3274	enterobacterial common antigen metabolic process
FOB99_RS01990	COG4682	membrane
FOB99_RS01995	COG4682	membrane
FOB99_RS02000	COG1070	Carbohydrate kinase
FOB99_RS02010	COG4213	ABC transporter substrate-binding protein
FOB99_RS02020	COG4214	carbohydrate transport
FOB99_RS02025	COG2207	Transcriptional regulator
FOB99_RS02025	COG1609	Transcriptional regulator
FOB99_RS02030	COG1609	Transcriptional regulator
FOB99_RS02030	COG2207	Transcriptional regulator
FOB99_RS02035	COG2992	FlgJ-related protein
FOB99_RS02040	COG0366	Alpha amylase catalytic
FOB99_RS02045	COG3977	Valine--pyruvate aminotransferase
FOB99_RS02050	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB99_RS02055	COG1414	Transcriptional regulator
FOB99_RS02080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOB99_RS02100	COG1012	belongs to the aldehyde dehydrogenase family
FOB99_RS02105	COG1454	alcohol dehydrogenase
FOB99_RS02110	COG3276	selenocysteine insertion sequence binding
FOB99_RS02120	COG0625	glutathione transferase activity
FOB99_RS02125	COG1566	PFAM secretion protein HlyD family protein
FOB99_RS02135	COG2213	PTS system mannitol-specific
FOB99_RS02135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS02145	COG3722	fumarate hydratase activity
FOB99_RS02175	COG1620	l-lactate permease
FOB99_RS02180	COG2186	Transcriptional regulator
FOB99_RS02190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOB99_RS02195	COG1045	serine acetyltransferase
FOB99_RS02210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB99_RS02215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB99_RS02225	COG4942	peptidase
FOB99_RS02230	COG2861	carbohydrate metabolic process
FOB99_RS02250	COG0156	8-amino-7-oxononanoate synthase activity
FOB99_RS02265	COG0859	PFAM glycosyl transferase family 9
FOB99_RS02270	COG0859	PFAM glycosyl transferase family 9
FOB99_RS02290	COG3642	lipopolysaccharide core region biosynthetic process
FOB99_RS02300	COG0515	serine threonine protein kinase
FOB99_RS02305	COG0438	transferase activity, transferring glycosyl groups
FOB99_RS02310	COG0859	PFAM glycosyl transferase family 9
FOB99_RS02320	COG1519	Transferase
FOB99_RS02350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB99_RS02375	COG1561	YicC-like family, N-terminal region
FOB99_RS02380	COG3645	SOS response
FOB99_RS02385	COG2860	membrane
FOB99_RS02395	COG0194	GDP metabolic process
FOB99_RS02405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB99_RS02410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB99_RS02415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB99_RS02420	COG0786	glutamate:sodium symporter activity
FOB99_RS02425	COG2233	PERMEase
FOB99_RS02430	COG2982	Protein involved in outer membrane biogenesis
FOB99_RS02435	COG1501	Belongs to the glycosyl hydrolase 31 family
FOB99_RS02450	COG0582	viral genome integration into host DNA
FOB99_RS02560	COG3188	usher protein
FOB99_RS02580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOB99_RS02585	COG0573	inorganic phosphate transmembrane transporter activity
FOB99_RS02590	COG0581	inorganic phosphate transmembrane transporter activity
FOB99_RS02595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB99_RS02600	COG0704	Plays a role in the regulation of phosphate uptake
FOB99_RS02605	COG3711	transcriptional antiterminator
FOB99_RS02610	COG1263	PTS System
FOB99_RS02610	COG2190	(PTS) system
FOB99_RS02610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB99_RS02635	COG2382	esterase
FOB99_RS02640	COG0363	glucosamine-6-phosphate deaminase activity
FOB99_RS02645	COG3196	Protein conserved in bacteria
FOB99_RS02650	COG4372	Transposase
FOB99_RS02655	COG3436	PFAM IS66 Orf2 family protein
FOB99_RS02670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB99_RS02675	COG2252	PERMEase
FOB99_RS02680	COG0431	NADPH-dependent FMN reductase
FOB99_RS02685	COG2091	lysine biosynthetic process via aminoadipic acid
FOB99_RS02710	COG0814	amino acid
FOB99_RS02765	COG0592	DNA-directed DNA polymerase activity
FOB99_RS02775	COG0187	DNA topoisomerase II activity
FOB99_RS02780	COG3753	Protein conserved in bacteria
FOB99_RS02785	COG0561	phosphatase activity
FOB99_RS02795	COG2186	Transcriptional regulator
FOB99_RS02800	COG3734	2-keto-3-deoxy-galactonokinase
FOB99_RS02805	COG0800	Aldolase
FOB99_RS02815	COG2271	Major facilitator Superfamily
FOB99_RS02825	COG0823	Involved in the tonB-independent uptake of proteins
FOB99_RS02830	COG5645	(Lipo)protein
FOB99_RS02850	COG2188	Transcriptional regulator
FOB99_RS02865	COG2207	Transcriptional regulator
FOB99_RS02870	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB99_RS02875	COG3119	arylsulfatase activity
FOB99_RS02880	COG3119	arylsulfatase activity
FOB99_RS02890	COG2149	membrane
FOB99_RS02900	COG0641	radical SAM
FOB99_RS02905	COG2814	Major facilitator Superfamily
FOB99_RS02920	COG0028	Belongs to the TPP enzyme family
FOB99_RS02925	COG0440	acetolactate synthase activity
FOB99_RS02930	COG2197	response regulator
FOB99_RS02935	COG3851	Histidine kinase
FOB99_RS02940	COG2271	Major facilitator Superfamily
FOB99_RS02945	COG2271	Major facilitator Superfamily
FOB99_RS02955	COG2252	PERMEase
FOB99_RS02980	COG3468	outer membrane autotransporter barrel domain protein
FOB99_RS03005	COG3385	transposase activity
FOB99_RS03060	COG3312	ion transport
FOB99_RS03075	COG0716	FMN binding
FOB99_RS03080	COG1522	sequence-specific DNA binding
FOB99_RS03100	COG3385	transposase activity
FOB99_RS03115	COG1129	ABC transporter
FOB99_RS03130	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB99_RS03140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB99_RS03145	COG1609	Transcriptional regulator
FOB99_RS03150	COG0477	Major facilitator Superfamily
FOB99_RS03155	COG2186	Transcriptional regulator
FOB99_RS03195	COG3085	chromosome segregation
FOB99_RS03220	COG3978	acetolactate synthase activity
FOB99_RS03225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB99_RS03235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB99_RS03240	COG0583	DNA-binding transcription factor activity
FOB99_RS03250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB99_RS03255	COG0210	DNA helicase
FOB99_RS03270	COG3118	belongs to the thioredoxin family
FOB99_RS03280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOB99_RS03285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB99_RS03290	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOB99_RS03295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOB99_RS03300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOB99_RS03305	COG1088	dTDP-glucose 4,6-dehydratase activity
FOB99_RS03310	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOB99_RS03315	COG0456	acetyltransferase
FOB99_RS03320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOB99_RS03325	COG2244	polysaccharide biosynthetic process
FOB99_RS03345	COG1113	amino acid transport
FOB99_RS03370	COG0641	radical SAM
FOB99_RS03380	COG3071	HemY protein
FOB99_RS03385	COG2959	enzyme of heme biosynthesis
FOB99_RS03390	COG1587	Uroporphyrinogen-III synthase
FOB99_RS03435	COG5567	small periplasmic lipoprotein
FOB99_RS03445	COG3159	Protein conserved in bacteria
FOB99_RS03455	COG1011	Hydrolase
FOB99_RS03460	COG0210	DNA helicase
FOB99_RS03465	COG3698	Phosphodiester glycosidase
FOB99_RS03470	COG3385	transposase activity
FOB99_RS03475	COG3698	Phosphodiester glycosidase
FOB99_RS03480	COG0598	Magnesium transport protein CorA
FOB99_RS03495	COG2962	Rard protein
FOB99_RS03500	COG2050	protein possibly involved in aromatic compounds catabolism
FOB99_RS03505	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FOB99_RS03510	COG0514	ATP-dependent DNA helicase (RecQ)
FOB99_RS03515	COG1280	lysine exporter protein (LysE YggA)
FOB99_RS03520	COG1280	lysine exporter protein (LysE YggA)
FOB99_RS03525	COG2267	carboxylic ester hydrolase activity
FOB99_RS03530	COG0561	phosphatase activity
FOB99_RS03535	COG0697	spore germination
FOB99_RS03540	COG0583	DNA-binding transcription factor activity
FOB99_RS03550	COG0412	Dienelactone hydrolase
FOB99_RS03555	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FOB99_RS03560	COG1322	Protein conserved in bacteria
FOB99_RS03570	COG3165	ubiquinone biosynthetic process from chorismate
FOB99_RS03580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB99_RS03585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB99_RS03590	COG0805	protein transport
FOB99_RS03600	COG0250	Participates in transcription elongation, termination and antitermination
FOB99_RS03610	COG0543	2 iron, 2 sulfur cluster binding
FOB99_RS03630	COG1739	Uncharacterized protein family UPF0029
FOB99_RS03635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB99_RS03640	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FOB99_RS03670	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOB99_RS03675	COG0746	molybdenum cofactor guanylyltransferase activity
FOB99_RS03680	COG3084	Protein conserved in bacteria
FOB99_RS03695	COG5339	Protein conserved in bacteria
FOB99_RS03700	COG0204	Acyl-transferase
FOB99_RS03705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB99_RS03705	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB99_RS03720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB99_RS03730	COG2204	response regulator
FOB99_RS03735	COG3852	Histidine kinase
FOB99_RS03740	COG0174	glutamine synthetase
FOB99_RS03750	COG2188	Transcriptional regulator
FOB99_RS03755	COG1082	Xylose isomerase domain protein TIM barrel
FOB99_RS03760	COG2271	Major facilitator Superfamily
FOB99_RS03775	COG2211	Major facilitator Superfamily
FOB99_RS03785	COG1501	Belongs to the glycosyl hydrolase 31 family
FOB99_RS03790	COG2017	converts alpha-aldose to the beta-anomer
FOB99_RS03795	COG2942	2-epimerase
FOB99_RS03805	COG2084	Dehydrogenase
FOB99_RS03810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB99_RS03815	COG1349	DNA-binding transcription factor activity
FOB99_RS03820	COG1011	Hydrolase
FOB99_RS03835	COG0456	acetyltransferase
FOB99_RS03860	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOB99_RS03865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOB99_RS03875	COG2864	formate dehydrogenase
FOB99_RS03880	COG0437	4 iron, 4 sulfur cluster binding
FOB99_RS03900	COG3711	transcriptional antiterminator
FOB99_RS03900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS03905	COG1363	Peptidase, m42
FOB99_RS03910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS03910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS03915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS03955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB99_RS03970	COG2258	MOSC domain
FOB99_RS03975	COG2205	protein histidine kinase activity
FOB99_RS03980	COG0745	RESPONSE REGULATOR receiver
FOB99_RS03985	COG3678	ATP-independent chaperone mediated protein folding
FOB99_RS04000	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOB99_RS04025	COG3691	Protein conserved in bacteria
FOB99_RS04030	COG0589	response to stress
FOB99_RS04040	COG1494	fructose-1,6-bisphosphatase
FOB99_RS04065	COG1575	Belongs to the MenA family. Type 1 subfamily
FOB99_RS04080	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOB99_RS04085	COG1609	Transcriptional regulator
FOB99_RS04090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB99_RS04100	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FOB99_RS04110	COG0626	cystathionine gamma-synthase activity
FOB99_RS04115	COG0460	homoserine dehydrogenase
FOB99_RS04115	COG0527	aspartate kinase activity
FOB99_RS04120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOB99_RS04130	COG0697	spore germination
FOB99_RS04155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS04160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS04165	COG1882	Formate acetyltransferase
FOB99_RS04170	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB99_RS04175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS04180	COG2207	Transcriptional regulator
FOB99_RS04185	COG2194	sulfuric ester hydrolase activity
FOB99_RS04215	COG3385	transposase activity
FOB99_RS04220	COG4948	Mandelate Racemase Muconate Lactonizing
FOB99_RS04240	COG0583	DNA-binding transcription factor activity
FOB99_RS04250	COG1309	transcriptional regulator
FOB99_RS04270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOB99_RS04300	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOB99_RS04300	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOB99_RS04335	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB99_RS04340	COG0250	Participates in transcription elongation, termination and antitermination
FOB99_RS04375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOB99_RS04385	COG2104	thiamine diphosphate biosynthetic process
FOB99_RS04390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB99_RS04425	COG3068	Protein conserved in bacteria
FOB99_RS04440	COG3678	ATP-independent chaperone mediated protein folding
FOB99_RS04445	COG4191	Histidine kinase
FOB99_RS04450	COG2204	response regulator
FOB99_RS04455	COG0151	Belongs to the GarS family
FOB99_RS04485	COG0456	acetyltransferase
FOB99_RS04500	COG2224	Isocitrate lyase
FOB99_RS04515	COG1414	Transcriptional regulator
FOB99_RS04520	COG0646	methionine synthase
FOB99_RS04520	COG1410	methionine synthase
FOB99_RS04525	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOB99_RS04585	COG3592	Divergent 4Fe-4S mono-cluster
FOB99_RS04600	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB99_RS04605	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB99_RS04605	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB99_RS04610	COG3647	Membrane
FOB99_RS04615	COG2211	Major facilitator Superfamily
FOB99_RS04620	COG1486	melibiose metabolic process
FOB99_RS04625	COG2169	Transcriptional regulator
FOB99_RS04630	COG1982	Orn Lys Arg decarboxylase major
FOB99_RS04635	COG2207	Transcriptional regulator
FOB99_RS04640	COG0531	amino acid
FOB99_RS04645	COG2194	sulfuric ester hydrolase activity
FOB99_RS04650	COG0745	RESPONSE REGULATOR receiver
FOB99_RS04655	COG0642	Histidine kinase
FOB99_RS04665	COG0477	Major facilitator Superfamily
FOB99_RS04675	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOB99_RS04680	COG2824	Alkylphosphonate utilization operon protein PhnA
FOB99_RS04685	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FOB99_RS04695	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FOB99_RS04700	COG3639	organic phosphonate transmembrane transporter activity
FOB99_RS04720	COG2207	Transcriptional regulator
FOB99_RS04725	COG0789	Transcriptional regulator
FOB99_RS04730	COG2252	PERMEase
FOB99_RS04735	COG0025	NhaP-type Na H and K H
FOB99_RS04740	COG1357	PFAM Pentapeptide repeats (8 copies)
FOB99_RS04750	COG3162	membrane
FOB99_RS04765	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FOB99_RS04770	COG0437	4 iron, 4 sulfur cluster binding
FOB99_RS04775	COG3301	Polysulphide reductase, NrfD
FOB99_RS04780	COG1138	Cytochrome C-type biogenesis protein
FOB99_RS04785	COG3088	subunit of a heme lyase
FOB99_RS04790	COG4235	cytochrome complex assembly
FOB99_RS04795	COG1301	dicarboxylic acid transport
FOB99_RS04800	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FOB99_RS04830	COG0629	single-stranded DNA binding
FOB99_RS04835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOB99_RS04840	COG2315	Protein conserved in bacteria
FOB99_RS04845	COG0432	Pfam Uncharacterised protein family UPF0047
FOB99_RS04850	COG3700	Belongs to the class B bacterial acid phosphatase family
FOB99_RS04860	COG1448	Aminotransferase
FOB99_RS04865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB99_RS04870	COG0305	Participates in initiation and elongation during chromosome replication
FOB99_RS04875	COG0604	alcohol dehydrogenase
FOB99_RS04885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB99_RS04895	COG0735	belongs to the Fur family
FOB99_RS04900	COG3237	CsbD-like
FOB99_RS04905	COG0534	Mate efflux family protein
FOB99_RS04915	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB99_RS04955	COG2182	Extracellular solute-binding protein
FOB99_RS04960	COG1175	transmembrane transport
FOB99_RS04965	COG3833	ABC-type maltose transport systems, permease component
FOB99_RS04970	COG0477	Major facilitator Superfamily
FOB99_RS04970	COG2814	Major facilitator Superfamily
FOB99_RS04990	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB99_RS05015	COG0527	aspartate kinase activity
FOB99_RS05020	COG4372	Transposase
FOB99_RS05025	COG3436	PFAM IS66 Orf2 family protein
FOB99_RS05045	COG3366	ferrous iron transmembrane transporter activity
FOB99_RS05050	COG0700	Nucleoside recognition
FOB99_RS05055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOB99_RS05060	COG0583	DNA-binding transcription factor activity
FOB99_RS05085	COG2186	Transcriptional regulator
FOB99_RS05090	COG0246	Mannitol dehydrogenase
FOB99_RS05100	COG2610	gluconate transmembrane transporter activity
FOB99_RS05105	COG3539	Fimbrial protein
FOB99_RS05110	COG3539	Fimbrial protein
FOB99_RS05115	COG3539	Fimbrial protein
FOB99_RS05135	COG3121	Chaperone
FOB99_RS05140	COG3539	Fimbrial protein
FOB99_RS05150	COG4974	Belongs to the 'phage' integrase family
FOB99_RS05160	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOB99_RS05180	COG1349	DNA-binding transcription factor activity
FOB99_RS05225	COG0582	viral genome integration into host DNA
FOB99_RS05235	COG1064	alcohol dehydrogenase
FOB99_RS05240	COG0433	COG0433 Predicted ATPase
FOB99_RS05245	COG0795	lipopolysaccharide-transporting ATPase activity
FOB99_RS05250	COG0795	lipopolysaccharide-transporting ATPase activity
FOB99_RS05260	COG2927	DNA polymerase III (CHI subunit)
FOB99_RS05270	COG4269	membrane
FOB99_RS05275	COG0456	acetyltransferase
FOB99_RS05280	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FOB99_RS05300	COG2731	YhcH YjgK YiaL family protein
FOB99_RS05305	COG1309	transcriptional regulator
FOB99_RS05310	COG1028	Short-chain dehydrogenase reductase Sdr
FOB99_RS05315	COG0251	oxidation-reduction process
FOB99_RS05335	COG0251	oxidation-reduction process
FOB99_RS05340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOB99_RS05350	COG1609	Transcriptional regulator
FOB99_RS05355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB99_RS05355	COG1263	PTS System
FOB99_RS05360	COG0366	Alpha amylase catalytic
FOB99_RS05365	COG1328	CTP reductase activity
FOB99_RS05370	COG0602	queuosine metabolic process
FOB99_RS05380	COG0312	modulator of DNA gyrase
FOB99_RS05390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB99_RS05400	COG3385	transposase activity
FOB99_RS05410	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB99_RS05415	COG1129	ABC transporter
FOB99_RS05425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOB99_RS05430	COG2105	PFAM AIG2 family protein
FOB99_RS05435	COG2911	Protein conserved in bacteria
FOB99_RS05440	COG0729	surface antigen
FOB99_RS05450	COG1253	flavin adenine dinucleotide binding
FOB99_RS05460	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOB99_RS05475	COG0737	Belongs to the 5'-nucleotidase family
FOB99_RS05480	COG1733	regulation of RNA biosynthetic process
FOB99_RS05485	COG0702	epimerase
FOB99_RS05490	COG0697	spore germination
FOB99_RS05500	COG1113	amino acid transport
FOB99_RS05505	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB99_RS05510	COG3061	Opacity-associated protein A
FOB99_RS05515	COG1309	transcriptional regulator
FOB99_RS05555	COG1309	transcriptional regulator
FOB99_RS05570	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB99_RS05575	COG1027	Aspartate ammonia-lyase
FOB99_RS05580	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOB99_RS05585	COG0531	amino acid
FOB99_RS05615	COG1509	lysine 2,3-aminomutase activity
FOB99_RS05625	COG5510	response to toxic substance
FOB99_RS05630	COG5510	response to toxic substance
FOB99_RS05635	COG2076	Multidrug Resistance protein
FOB99_RS05640	COG3040	lipid binding
FOB99_RS05645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOB99_RS05660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB99_RS05665	COG1053	succinate dehydrogenase
FOB99_RS05675	COG0531	amino acid
FOB99_RS05690	COG1511	domain protein
FOB99_RS05690	COG3264	Mechanosensitive ion channel
FOB99_RS05735	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB99_RS05740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB99_RS05740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOB99_RS05745	COG0802	atpase or kinase
FOB99_RS05750	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOB99_RS05770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB99_RS05775	COG0330	HflC and HflK could
FOB99_RS05780	COG0330	HflC and HflK could
FOB99_RS05785	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FOB99_RS05805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB99_RS05815	COG3766	membrane
FOB99_RS05820	COG5463	Belongs to the UPF0441 family
FOB99_RS05825	COG0754	glutathionylspermidine amidase activity
FOB99_RS05850	COG3650	response to hydrogen peroxide
FOB99_RS05855	COG1073	alpha beta
FOB99_RS05915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOB99_RS05950	COG0732	type I restriction modification DNA specificity domain
FOB99_RS05975	COG0523	cobalamin synthesis protein
FOB99_RS05980	COG2879	small protein
FOB99_RS05985	COG1966	Carbon starvation protein
FOB99_RS05990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB99_RS06020	COG3971	2-oxopent-4-enoate hydratase activity
FOB99_RS06030	COG3384	dioxygenase
FOB99_RS06035	COG1012	belongs to the aldehyde dehydrogenase family
FOB99_RS06040	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB99_RS06045	COG1846	Transcriptional regulator
FOB99_RS06050	COG0840	transmembrane signaling receptor activity
FOB99_RS06055	COG2271	Major facilitator Superfamily
FOB99_RS06060	COG1802	Transcriptional regulator
FOB99_RS06080	COG1484	DNA-dependent DNA replication
FOB99_RS06095	COG2966	Psort location CytoplasmicMembrane, score
FOB99_RS06110	COG2197	response regulator
FOB99_RS06115	COG4114	ferric iron reductase
FOB99_RS06145	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FOB99_RS06150	COG0456	acetyltransferase
FOB99_RS06155	COG1011	Hydrolase
FOB99_RS06165	COG2823	Periplasmic or secreted lipoprotein
FOB99_RS06175	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB99_RS06180	COG0084	hydrolase, TatD family'
FOB99_RS06185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB99_RS06190	COG1328	CTP reductase activity
FOB99_RS06225	COG3726	membrane protein affecting hemolysin expression
FOB99_RS06230	COG0560	Phosphoserine phosphatase
FOB99_RS06235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOB99_RS06240	COG1056	cytidyltransferase-related domain
FOB99_RS06240	COG3172	ATPase kinase involved in NAD metabolism
FOB99_RS06250	COG0488	(ABC) transporter
FOB99_RS06255	COG0741	lytic transglycosylase activity
FOB99_RS06275	COG3708	Transcriptional regulator
FOB99_RS06275	COG2207	Transcriptional regulator
FOB99_RS06280	COG3045	CreA protein
FOB99_RS06285	COG0745	RESPONSE REGULATOR receiver
FOB99_RS06290	COG2205	protein histidine kinase activity
FOB99_RS06295	COG4452	Inner membrane protein CreD
FOB99_RS06300	COG0745	RESPONSE REGULATOR receiver
FOB99_RS06310	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FOB99_RS06320	COG0460	homoserine dehydrogenase
FOB99_RS06320	COG0527	aspartate kinase activity
FOB99_RS06330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOB99_RS06350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB99_RS06355	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB99_RS06360	COG1584	GPR1 FUN34 yaaH family protein
FOB99_RS06365	COG4735	regulation of single-species biofilm formation
FOB99_RS06395	COG0583	DNA-binding transcription factor activity
FOB99_RS06420	COG0196	riboflavin kinase activity
FOB99_RS06435	COG1047	Peptidyl-prolyl cis-trans
FOB99_RS06455	COG0505	Belongs to the CarA family
FOB99_RS06460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB99_RS06520	COG2271	Major facilitator Superfamily
FOB99_RS06535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOB99_RS06560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB99_RS06570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOB99_RS06575	COG0564	pseudouridine synthase activity
FOB99_RS06585	COG0417	DNA replication proofreading
FOB99_RS06590	COG0235	Class ii aldolase
FOB99_RS06605	COG4977	sequence-specific DNA binding
FOB99_RS06610	COG0586	Pfam SNARE associated Golgi protein
FOB99_RS06620	COG1178	ABC-type Fe3 transport system permease component
FOB99_RS06625	COG4143	(ABC) transporter
FOB99_RS06640	COG2814	Major facilitator Superfamily
FOB99_RS06670	COG0583	DNA-binding transcription factor activity
FOB99_RS06675	COG0028	Belongs to the TPP enzyme family
FOB99_RS06680	COG0440	acetolactate synthase activity
FOB99_RS06690	COG1609	Transcriptional regulator
FOB99_RS06710	COG3116	cell division
FOB99_RS06715	COG0768	penicillin binding
FOB99_RS06725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB99_RS06740	COG0772	Belongs to the SEDS family
FOB99_RS06760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOB99_RS06765	COG0849	cell division
FOB99_RS06770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOB99_RS06790	COG0494	nUDIX hydrolase
FOB99_RS06815	COG1459	type II secretion system
FOB99_RS06825	COG4969	Belongs to the N-Me-Phe pilin family
FOB99_RS06830	COG0157	Belongs to the NadC ModD family
FOB99_RS06835	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB99_RS06840	COG3725	Membrane protein required for beta-lactamase induction
FOB99_RS06850	COG2186	Transcriptional regulator
FOB99_RS06855	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOB99_RS06860	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB99_RS06865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB99_RS06875	COG1049	propionate catabolic process, 2-methylcitrate cycle
FOB99_RS06900	COG2132	Multicopper oxidase
FOB99_RS06905	COG4993	Dehydrogenase
FOB99_RS06910	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FOB99_RS06915	COG0288	reversible hydration of carbon dioxide
FOB99_RS06920	COG1131	(ABC) transporter
FOB99_RS06925	COG0842	Transport permease protein
FOB99_RS06930	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS06935	COG0726	polysaccharide deacetylase
FOB99_RS06945	COG5464	transposase or invertase
FOB99_RS06970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB99_RS06975	COG0617	tRNA 3'-terminal CCA addition
FOB99_RS06985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB99_RS06995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOB99_RS07000	COG1643	Atp-dependent helicase
FOB99_RS07005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB99_RS07010	COG4774	siderophore transport
FOB99_RS07015	COG1120	ATPase activity
FOB99_RS07020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB99_RS07025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB99_RS07050	COG2860	membrane
FOB99_RS07070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB99_RS07095	COG0024	Methionine aminopeptidase
FOB99_RS07125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB99_RS07130	COG0575	Belongs to the CDS family
FOB99_RS07135	COG0750	zinc metalloprotease
FOB99_RS07145	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FOB99_RS07150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB99_RS07175	COG0587	DNA-directed DNA polymerase activity
FOB99_RS07190	COG0346	lactoylglutathione lyase activity
FOB99_RS07200	COG4568	rho-dependent transcription termination
FOB99_RS07210	COG4681	YaeQ
FOB99_RS07215	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOB99_RS07220	COG3015	lipoprotein NlpE involved in copper resistance
FOB99_RS07225	COG0791	NLP P60 protein
FOB99_RS07235	COG1720	tRNA m6t6A37 methyltransferase activity
FOB99_RS07245	COG1464	Belongs to the NlpA lipoprotein family
FOB99_RS07250	COG2011	ABC-type metal ion transport system permease component
FOB99_RS07255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB99_RS07260	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB99_RS07295	COG0656	L-ascorbic acid biosynthetic process
FOB99_RS07300	COG3385	transposase activity
FOB99_RS07305	COG0583	DNA-binding transcription factor activity
FOB99_RS07315	COG2226	methyltransferase
FOB99_RS07320	COG1388	LysM domain
FOB99_RS07320	COG0741	lytic transglycosylase activity
FOB99_RS07330	COG2226	methyltransferase
FOB99_RS07340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB99_RS07395	COG3344	reverse transcriptase
FOB99_RS07475	COG1785	Belongs to the alkaline phosphatase family
FOB99_RS07490	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB99_RS07510	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FOB99_RS07515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOB99_RS07520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB99_RS07565	COG0113	porphobilinogen synthase activity
FOB99_RS07570	COG2175	clavaminate synthase activity
FOB99_RS07575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB99_RS07585	COG4521	taurine ABC transporter
FOB99_RS07605	COG1556	Lactate utilization protein
FOB99_RS07610	COG1139	Iron-sulfur cluster binding protein
FOB99_RS07615	COG0247	lactate metabolic process
FOB99_RS07635	COG3501	Rhs element vgr protein
FOB99_RS07655	COG3209	COG3209 Rhs family protein
FOB99_RS07675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB99_RS07685	COG1960	acyl-CoA dehydrogenase activity
FOB99_RS07695	COG0121	glutamine amidotransferase
FOB99_RS07700	COG3034	peptidoglycan biosynthetic process
FOB99_RS07710	COG1943	Transposase
FOB99_RS07730	COG2161	toxin-antitoxin pair type II binding
FOB99_RS07740	COG0454	-acetyltransferase
FOB99_RS07745	COG1690	Belongs to the RtcB family
FOB99_RS07755	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB99_RS07775	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB99_RS07840	COG2246	polysaccharide biosynthetic process
FOB99_RS07880	COG0582	viral genome integration into host DNA
FOB99_RS07905	COG3344	reverse transcriptase
FOB99_RS07915	COG3706	GGDEF domain
FOB99_RS07920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOB99_RS07940	COG4126	flavin adenine dinucleotide binding
FOB99_RS07965	COG1940	carbohydrate kinase activity
FOB99_RS07970	COG2814	Major facilitator Superfamily
FOB99_RS07975	COG0419	ATPase involved in DNA repair
FOB99_RS07980	COG0420	3'-5' exonuclease activity
FOB99_RS07990	COG5002	protein histidine kinase activity
FOB99_RS07995	COG1114	Component of the transport system for branched-chain amino acids
FOB99_RS08000	COG1113	amino acid transport
FOB99_RS08005	COG0366	Alpha amylase catalytic
FOB99_RS08025	COG1862	Preprotein translocase
FOB99_RS08030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB99_RS08035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB99_RS08040	COG1403	HNH endonuclease
FOB99_RS08045	COG3248	Nucleoside-binding outer membrane protein
FOB99_RS08050	COG4238	major outer membrane lipoprotein
FOB99_RS08060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB99_RS08060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB99_RS08075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOB99_RS08080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOB99_RS08085	COG0667	Aldo Keto reductase
FOB99_RS08095	COG0142	geranyltranstransferase activity
FOB99_RS08110	COG0693	protein deglycase activity
FOB99_RS08115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOB99_RS08155	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOB99_RS08160	COG1845	cytochrome c oxidase, subunit III
FOB99_RS08185	COG3436	PFAM IS66 Orf2 family protein
FOB99_RS08195	COG2223	nitrite transmembrane transporter activity
FOB99_RS08200	COG3056	Lipoprotein
FOB99_RS08205	COG0271	Belongs to the BolA IbaG family
FOB99_RS08225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOB99_RS08230	COG0776	regulation of translation
FOB99_RS08235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB99_RS08240	COG1555	photosystem II stabilization
FOB99_RS08245	COG0824	Thioesterase
FOB99_RS08265	COG1522	sequence-specific DNA binding
FOB99_RS08270	COG1132	(ABC) transporter
FOB99_RS08275	COG1132	(ABC) transporter
FOB99_RS08280	COG0347	Belongs to the P(II) protein family
FOB99_RS08285	COG0004	ammonium transporteR
FOB99_RS08290	COG1946	Acyl-CoA thioesterase
FOB99_RS08295	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FOB99_RS08300	COG3385	transposase activity
FOB99_RS08305	COG3695	enzyme binding
FOB99_RS08315	COG5507	3-demethylubiquinone-9 3-methyltransferase
FOB99_RS08320	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FOB99_RS08345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB99_RS08350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB99_RS08355	COG1309	transcriptional regulator
FOB99_RS08360	COG3264	Mechanosensitive ion channel
FOB99_RS08360	COG1196	nuclear chromosome segregation
FOB99_RS08370	COG3923	Primosomal replication protein n
FOB99_RS08375	COG2832	Protein of unknown function (DUF454)
FOB99_RS08385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOB99_RS08420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB99_RS08425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB99_RS08425	COG4651	solute:proton antiporter activity
FOB99_RS08430	COG2223	nitrite transmembrane transporter activity
FOB99_RS08435	COG0737	Belongs to the 5'-nucleotidase family
FOB99_RS08440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB99_RS08445	COG3735	TraB family
FOB99_RS08450	COG3093	addiction module antidote protein HigA
FOB99_RS08455	COG2217	Heavy metal translocating P-type atpase
FOB99_RS08465	COG0531	amino acid
FOB99_RS08470	COG0789	Transcriptional regulator
FOB99_RS08475	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOB99_RS08480	COG0330	HflC and HflK could
FOB99_RS08485	COG4619	ABC transporter
FOB99_RS08490	COG0390	transport system, permease component
FOB99_RS08495	COG3118	belongs to the thioredoxin family
FOB99_RS08500	COG0300	oxidoreductase activity
FOB99_RS08510	COG4181	ATPase activity
FOB99_RS08525	COG0583	DNA-binding transcription factor activity
FOB99_RS08535	COG1414	Transcriptional regulator
FOB99_RS08540	COG3960	tartronate-semialdehyde synthase activity
FOB99_RS08560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB99_RS08570	COG0549	Belongs to the carbamate kinase family
FOB99_RS08575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOB99_RS08580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOB99_RS08590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB99_RS08600	COG1988	membrane-bound metal-dependent
FOB99_RS08605	COG2501	S4 domain
FOB99_RS08615	COG3539	Fimbrial protein
FOB99_RS08635	COG2207	Transcriptional regulator
FOB99_RS08650	COG1215	transferase activity, transferring glycosyl groups
FOB99_RS08655	COG5002	protein histidine kinase activity
FOB99_RS08660	COG0745	RESPONSE REGULATOR receiver
FOB99_RS08665	COG1538	Outer membrane efflux protein
FOB99_RS08670	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB99_RS08705	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB99_RS08710	COG1113	amino acid transport
FOB99_RS08715	COG0668	transmembrane transport
FOB99_RS08720	COG0778	Nitroreductase
FOB99_RS08725	COG2315	Protein conserved in bacteria
FOB99_RS08775	COG2977	Belongs to the P-Pant transferase superfamily
FOB99_RS08780	COG4771	TonB-dependent receptor
FOB99_RS08785	COG2382	esterase
FOB99_RS08790	COG3251	PFAM MbtH domain protein
FOB99_RS08810	COG1120	ATPase activity
FOB99_RS08815	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB99_RS08820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB99_RS08830	COG4592	Periplasmic binding protein
FOB99_RS08840	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOB99_RS08845	COG3433	isochorismatase activity
FOB99_RS08845	COG1535	isochorismatase
FOB99_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
FOB99_RS08860	COG1966	Carbon starvation protein
FOB99_RS08865	COG2879	small protein
FOB99_RS08870	COG0371	Dehydrogenase
FOB99_RS08875	COG0436	Aminotransferase
FOB99_RS08890	COG3344	reverse transcriptase
FOB99_RS08915	COG1783	phage Terminase large subunit
FOB99_RS08930	COG1783	phage Terminase large subunit
FOB99_RS08975	COG3423	Transcriptional regulator
FOB99_RS08990	COG3069	C4-dicarboxylate transmembrane transporter activity
FOB99_RS09010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB99_RS09015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB99_RS09025	COG0583	DNA-binding transcription factor activity
FOB99_RS09040	COG1686	Belongs to the peptidase S11 family
FOB99_RS09045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOB99_RS09050	COG0772	Belongs to the SEDS family
FOB99_RS09055	COG0768	penicillin binding
FOB99_RS09065	COG0799	negative regulation of ribosome biogenesis
FOB99_RS09070	COG0406	alpha-ribazole phosphatase activity
FOB99_RS09080	COG1466	dna polymerase III delta subunit
FOB99_RS09095	COG2888	peptidyl-tyrosine sulfation
FOB99_RS09100	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FOB99_RS09110	COG2214	Heat shock protein DnaJ domain protein
FOB99_RS09115	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FOB99_RS09125	COG2214	Heat shock protein DnaJ domain protein
FOB99_RS09140	COG1126	abc transporter atp-binding protein
FOB99_RS09145	COG0765	amino acid transport
FOB99_RS09150	COG0765	amino acid transport
FOB99_RS09155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB99_RS09165	COG4535	Mg2 and Co2 transporter CorC
FOB99_RS09175	COG1702	phosphate starvation-inducible protein PhoH
FOB99_RS09185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB99_RS09225	COG0367	asparagine synthase
FOB99_RS09235	COG1940	carbohydrate kinase activity
FOB99_RS09235	COG1846	Transcriptional regulator
FOB99_RS09240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOB99_RS09250	COG2190	(PTS) system
FOB99_RS09250	COG1263	PTS System
FOB99_RS09250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB99_RS09270	COG0735	belongs to the Fur family
FOB99_RS09280	COG0716	FMN binding
FOB99_RS09290	COG0596	Alpha beta hydrolase
FOB99_RS09295	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FOB99_RS09300	COG0033	Phosphoglucomutase
FOB99_RS09305	COG0531	amino acid
FOB99_RS09365	COG3209	COG3209 Rhs family protein
FOB99_RS09380	COG3272	Protein of unknown function (DUF1722)
FOB99_RS09385	COG0415	Belongs to the DNA photolyase family
FOB99_RS09395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOB99_RS09400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOB99_RS09405	COG1984	allophanate hydrolase subunit 2
FOB99_RS09410	COG1984	allophanate hydrolase subunit 2
FOB99_RS09425	COG3180	Ammonia monooxygenase
FOB99_RS09435	COG3121	Chaperone
FOB99_RS09440	COG3188	usher protein
FOB99_RS09445	COG3539	Fimbrial protein
FOB99_RS09450	COG0372	Belongs to the citrate synthase family
FOB99_RS09460	COG2009	succinate dehydrogenase
FOB99_RS09465	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOB99_RS09470	COG1053	succinate dehydrogenase
FOB99_RS09475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB99_RS09480	COG0567	Dehydrogenase, E1 component
FOB99_RS09485	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB99_RS09495	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOB99_RS09500	COG2188	Transcriptional regulator
FOB99_RS09505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS09505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS09505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS09510	COG0383	alpha-mannosidase activity
FOB99_RS09520	COG1271	oxidase subunit
FOB99_RS09525	COG1294	oxidase, subunit
FOB99_RS09530	COG4890	Cyd operon protein YbgT
FOB99_RS09535	COG3790	cyd operon protein YbgE
FOB99_RS09540	COG0824	Thioesterase
FOB99_RS09545	COG0811	peptide transport
FOB99_RS09550	COG0848	biopolymer transport protein
FOB99_RS09555	COG3064	Membrane
FOB99_RS09565	COG2885	chlorophyll binding
FOB99_RS09570	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FOB99_RS09605	COG3201	nicotinamide mononucleotide transporter
FOB99_RS09620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB99_RS09630	COG2017	converts alpha-aldose to the beta-anomer
FOB99_RS09640	COG1085	galactose-1-phosphate uridylyltransferase
FOB99_RS09645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB99_RS09650	COG1119	ATPase activity
FOB99_RS09655	COG2005	Transcriptional regulator
FOB99_RS09655	COG3585	molybdate ion transport
FOB99_RS09665	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOB99_RS09670	COG4149	molybdate abc transporter
FOB99_RS09680	COG0561	phosphatase activity
FOB99_RS09685	COG0582	viral genome integration into host DNA
FOB99_RS09695	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FOB99_RS09705	COG2301	Belongs to the HpcH HpaI aldolase family
FOB99_RS09710	COG3051	citrate lyase alpha subunit
FOB99_RS09730	COG3719	Belongs to the RNase T2 family
FOB99_RS09735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB99_RS09740	COG1063	alcohol dehydrogenase
FOB99_RS09750	COG3634	alkyl hydroperoxide reductase activity
FOB99_RS09755	COG0450	alkyl hydroperoxide reductase
FOB99_RS09760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB99_RS09765	COG0583	DNA-binding transcription factor activity
FOB99_RS09790	COG3344	reverse transcriptase
FOB99_RS09850	COG1484	DNA-dependent DNA replication
FOB99_RS09855	COG0305	Participates in initiation and elongation during chromosome replication
FOB99_RS09905	COG3772	lysozyme
FOB99_RS10040	COG1881	PFAM PEBP family protein
FOB99_RS10045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB99_RS10060	COG2226	methyltransferase
FOB99_RS10065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOB99_RS10075	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOB99_RS10085	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB99_RS10095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOB99_RS10100	COG0314	molybdopterin synthase activity
FOB99_RS10105	COG0670	Belongs to the BI1 family
FOB99_RS10110	COG0670	Belongs to the BI1 family
FOB99_RS10115	COG0392	lysyltransferase activity
FOB99_RS10125	COG3568	Endonuclease Exonuclease Phosphatase
FOB99_RS10135	COG0842	Transport permease protein
FOB99_RS10140	COG0842	Transport permease protein
FOB99_RS10145	COG1131	(ABC) transporter
FOB99_RS10155	COG1309	transcriptional regulator
FOB99_RS10175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB99_RS10180	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOB99_RS10190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB99_RS10205	COG3385	transposase activity
FOB99_RS10230	COG1126	abc transporter atp-binding protein
FOB99_RS10235	COG0765	amino acid transport
FOB99_RS10240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB99_RS10250	COG5006	permease, DMT superfamily
FOB99_RS10260	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOB99_RS10265	COG2194	sulfuric ester hydrolase activity
FOB99_RS10275	COG1321	iron dependent repressor
FOB99_RS10280	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOB99_RS10285	COG1376	ErfK ybiS ycfS ynhG family protein
FOB99_RS10290	COG0488	(ABC) transporter
FOB99_RS10300	COG0561	phosphatase activity
FOB99_RS10305	COG1882	Formate acetyltransferase
FOB99_RS10310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB99_RS10315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB99_RS10320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB99_RS10325	COG0303	'Molybdopterin
FOB99_RS10330	COG1446	asparaginase
FOB99_RS10360	COG2199	diguanylate cyclase activity
FOB99_RS10380	COG0625	glutathione transferase activity
FOB99_RS10400	COG1349	DNA-binding transcription factor activity
FOB99_RS10405	COG0671	phosphoesterase, PA-phosphatase related
FOB99_RS10410	COG2814	Major facilitator Superfamily
FOB99_RS10420	COG0561	phosphatase activity
FOB99_RS10425	COG0738	Major facilitator superfamily
FOB99_RS10430	COG3226	Transcriptional regulator
FOB99_RS10445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB99_RS10455	COG0778	Nitroreductase
FOB99_RS10470	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOB99_RS10475	COG3842	ATPase activity
FOB99_RS10480	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB99_RS10485	COG1177	transmembrane transport
FOB99_RS10500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB99_RS10505	COG4160	amino acid transport
FOB99_RS10510	COG4215	(ABC) transporter
FOB99_RS10515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB99_RS10520	COG1126	abc transporter atp-binding protein
FOB99_RS10540	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB99_RS10545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB99_RS10550	COG0702	epimerase
FOB99_RS10555	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOB99_RS10560	COG0028	Belongs to the TPP enzyme family
FOB99_RS10565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB99_RS10575	COG2431	L-lysine efflux transmembrane transporter activity
FOB99_RS10595	COG3593	DNA synthesis involved in DNA repair
FOB99_RS10600	COG2990	Protein conserved in bacteria
FOB99_RS10605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB99_RS10615	COG1278	Cold shock
FOB99_RS10625	COG0542	response to heat
FOB99_RS10645	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOB99_RS10650	COG4988	ABC transporter
FOB99_RS10655	COG0492	ferredoxin-NADP+ reductase activity
FOB99_RS10660	COG1522	sequence-specific DNA binding
FOB99_RS10675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB99_RS10690	COG0437	4 iron, 4 sulfur cluster binding
FOB99_RS10695	COG3302	dmso reductase anchor subunit
FOB99_RS10700	COG1335	isochorismatase
FOB99_RS10715	COG3436	PFAM IS66 Orf2 family protein
FOB99_RS10720	COG4372	Transposase
FOB99_RS10770	COG1396	sequence-specific DNA binding
FOB99_RS10790	COG3646	Phage regulatory protein
FOB99_RS10835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOB99_RS10850	COG2828	Protein conserved in bacteria
FOB99_RS10855	COG0471	metal ion transport
FOB99_RS10860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOB99_RS10865	COG4677	pectinesterase activity
FOB99_RS10870	COG0582	viral genome integration into host DNA
FOB99_RS10895	COG3436	PFAM IS66 Orf2 family protein
FOB99_RS10930	COG0583	DNA-binding transcription factor activity
FOB99_RS10965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB99_RS10970	COG1882	Formate acetyltransferase
FOB99_RS10975	COG2116	formate transmembrane transporter activity
FOB99_RS10980	COG1944	ATP diphosphatase activity
FOB99_RS11000	COG3385	transposase activity
FOB99_RS11005	COG0501	Belongs to the peptidase M48B family
FOB99_RS11015	COG0539	negative regulation of cytoplasmic translation
FOB99_RS11040	COG3214	Protein conserved in bacteria
FOB99_RS11055	COG3173	Aminoglycoside phosphotransferase
FOB99_RS11060	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOB99_RS11065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB99_RS11075	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FOB99_RS11090	COG2989	Protein conserved in bacteria
FOB99_RS11095	COG3108	Peptidase M15
FOB99_RS11100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB99_RS11105	COG1448	Aminotransferase
FOB99_RS11110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB99_RS11125	COG0308	aminopeptidase N
FOB99_RS11145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB99_RS11155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB99_RS11160	COG0431	NADPH-dependent FMN reductase
FOB99_RS11180	COG3188	usher protein
FOB99_RS11185	COG3539	Fimbrial protein
FOB99_RS11195	COG3539	Fimbrial protein
FOB99_RS11200	COG3121	Chaperone
FOB99_RS11215	COG3217	Mosc domain protein beta barrel domain protein
FOB99_RS11215	COG0633	Ferredoxin
FOB99_RS11225	COG0488	(ABC) transporter
FOB99_RS11230	COG2995	paraquat-inducible protein a
FOB99_RS11235	COG3008	intermembrane lipid transfer
FOB99_RS11235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB99_RS11240	COG3009	Protein conserved in bacteria
FOB99_RS11245	COG3130	regulation of translation
FOB99_RS11255	COG1067	ATP-dependent peptidase activity
FOB99_RS11275	COG3070	regulator of competence-specific genes
FOB99_RS11285	COG1289	transmembrane transporter activity
FOB99_RS11290	COG3304	Inner membrane component domain
FOB99_RS11295	COG0210	DNA helicase
FOB99_RS11310	COG1832	CoA-binding protein
FOB99_RS11330	COG2920	part of a sulfur-relay system
FOB99_RS11335	COG0670	Belongs to the BI1 family
FOB99_RS11345	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FOB99_RS11350	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FOB99_RS11355	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FOB99_RS11360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOB99_RS11365	COG1999	signal sequence binding
FOB99_RS11370	COG1773	rubredoxin
FOB99_RS11375	COG1271	oxidase subunit
FOB99_RS11380	COG1294	oxidase, subunit
FOB99_RS11400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB99_RS11405	COG1596	polysaccharide export
FOB99_RS11410	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB99_RS11430	COG1278	Cold shock
FOB99_RS11440	COG1278	Cold shock
FOB99_RS11460	COG0348	domain, Protein
FOB99_RS11470	COG1879	ABC-type sugar transport system periplasmic component
FOB99_RS11475	COG0745	RESPONSE REGULATOR receiver
FOB99_RS11480	COG3005	denitrification pathway
FOB99_RS11535	COG3729	General stress protein
FOB99_RS11540	COG2233	PERMEase
FOB99_RS11575	COG1309	transcriptional regulator
FOB99_RS11595	COG2822	iron ion transport
FOB99_RS11605	COG1702	phosphate starvation-inducible protein PhoH
FOB99_RS11625	COG0582	viral genome integration into host DNA
FOB99_RS11695	COG0640	Transcriptional regulator
FOB99_RS11735	COG0726	polysaccharide deacetylase
FOB99_RS11745	COG3344	reverse transcriptase
FOB99_RS11755	COG2085	NADP oxidoreductase coenzyme F420-dependent
FOB99_RS11760	COG1120	ATPase activity
FOB99_RS11765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB99_RS11770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB99_RS11775	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOB99_RS11780	COG4772	TonB-dependent receptor
FOB99_RS11785	COG3712	iron ion homeostasis
FOB99_RS11790	COG1595	DNA-templated transcription, initiation
FOB99_RS11825	COG4372	Transposase
FOB99_RS11830	COG3436	PFAM IS66 Orf2 family protein
FOB99_RS11890	COG3468	outer membrane autotransporter barrel domain protein
FOB99_RS11910	COG2003	Belongs to the UPF0758 family
FOB99_RS11970	COG3381	protein complex oligomerization
FOB99_RS11995	COG2197	response regulator
FOB99_RS12035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB99_RS12050	COG2943	transferase activity, transferring hexosyl groups
FOB99_RS12110	COG1560	Kdo2-lipid A biosynthetic process
FOB99_RS12125	COG3038	cytochrome b561
FOB99_RS12160	COG2999	glutathione oxidoreductase activity
FOB99_RS12170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB99_RS12180	COG0673	inositol 2-dehydrogenase activity
FOB99_RS12185	COG0728	peptidoglycan biosynthetic process
FOB99_RS12190	COG3418	PFAM FlgN family protein
FOB99_RS12195	COG2747	anti-sigma28 factor FlgM
FOB99_RS12200	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FOB99_RS12205	COG1815	bacterial-type flagellum-dependent cell motility
FOB99_RS12215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOB99_RS12220	COG1749	Flagellar hook protein flgE
FOB99_RS12230	COG4786	Flagellar basal body rod
FOB99_RS12245	COG3951	Flagellar rod assembly protein muramidase FlgJ
FOB99_RS12245	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB99_RS12260	COG1530	ribonuclease E activity
FOB99_RS12265	COG0564	pseudouridine synthase activity
FOB99_RS12270	COG0424	maF-like protein
FOB99_RS12275	COG1399	metal-binding, possibly nucleic acid-binding protein
FOB99_RS12295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOB99_RS12300	COG1028	Short-chain dehydrogenase reductase Sdr
FOB99_RS12310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB99_RS12315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB99_RS12320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB99_RS12330	COG0470	DNA polymerase III
FOB99_RS12335	COG0084	hydrolase, TatD family'
FOB99_RS12340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB99_RS12340	COG1263	PTS System
FOB99_RS12350	COG0537	adenosine 5'-monophosphoramidase activity
FOB99_RS12355	COG5633	Lipoprotein
FOB99_RS12360	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FOB99_RS12380	COG1252	NADH dehydrogenase
FOB99_RS12385	COG3134	Outer membrane lipoprotein
FOB99_RS12390	COG1309	transcriptional regulator
FOB99_RS12400	COG1376	ErfK ybiS ycfS ynhG family protein
FOB99_RS12400	COG1388	LysM domain
FOB99_RS12405	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB99_RS12410	COG4763	Acyl-transferase
FOB99_RS12415	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB99_RS12425	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB99_RS12440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOB99_RS12445	COG1177	transmembrane transport
FOB99_RS12455	COG3842	ATPase activity
FOB99_RS12470	COG2850	peptidyl-arginine hydroxylation
FOB99_RS12585	COG1802	Transcriptional regulator
FOB99_RS12585	COG4626	Terminase
FOB99_RS12610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOB99_RS12635	COG0538	isocitrate dehydrogenase activity
FOB99_RS12645	COG2200	EAL domain
FOB99_RS12695	COG2894	cell division
FOB99_RS12740	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB99_RS12755	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOB99_RS12760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB99_RS12780	COG2719	SpoVR family
FOB99_RS12790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB99_RS12805	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOB99_RS12815	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FOB99_RS12835	COG0157	Belongs to the NadC ModD family
FOB99_RS12840	COG0500	methyltransferase
FOB99_RS12845	COG1120	ATPase activity
FOB99_RS12875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB99_RS12875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS12875	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FOB99_RS12880	COG1461	Dihydroxyacetone kinase
FOB99_RS12885	COG2376	Dihydroxyacetone kinase
FOB99_RS12890	COG3284	Transcriptional regulator
FOB99_RS12895	COG3468	outer membrane autotransporter barrel domain protein
FOB99_RS12900	COG0012	GTP binding
FOB99_RS12915	COG0659	secondary active sulfate transmembrane transporter activity
FOB99_RS12920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOB99_RS12945	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB99_RS12950	COG3094	Invasion gene expression up-regulator, SirB
FOB99_RS12955	COG2912	Transglutaminase-like superfamily
FOB99_RS12970	COG0387	Pfam Sodium calcium exchanger
FOB99_RS12975	COG4572	Cation transport regulator
FOB99_RS12980	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FOB99_RS12985	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOB99_RS12990	COG4932	domain protein
FOB99_RS12995	COG2197	response regulator
FOB99_RS13000	COG3850	Histidine kinase
FOB99_RS13005	COG2223	nitrite transmembrane transporter activity
FOB99_RS13010	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOB99_RS13015	COG1140	nitrate reductase beta subunit
FOB99_RS13020	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOB99_RS13025	COG2181	nitrate reductase activity
FOB99_RS13040	COG0788	formyltetrahydrofolate deformylase activity
FOB99_RS13050	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB99_RS13055	COG0745	RESPONSE REGULATOR receiver
FOB99_RS13060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOB99_RS13070	COG1435	thymidine kinase activity
FOB99_RS13075	COG3385	transposase activity
FOB99_RS13080	COG1012	belongs to the aldehyde dehydrogenase family
FOB99_RS13080	COG1454	alcohol dehydrogenase
FOB99_RS13085	COG2095	MarC family integral membrane protein
FOB99_RS13100	COG4166	transmembrane transport
FOB99_RS13105	COG0601	transmembrane transport
FOB99_RS13110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB99_RS13115	COG0444	Belongs to the ABC transporter superfamily
FOB99_RS13120	COG4608	Belongs to the ABC transporter superfamily
FOB99_RS13140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB99_RS13150	COG2350	Protein conserved in bacteria
FOB99_RS13155	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FOB99_RS13160	COG1607	acyl-coa hydrolase
FOB99_RS13180	COG3047	cAMP biosynthetic process
FOB99_RS13185	COG3685	Protein conserved in bacteria
FOB99_RS13190	COG3685	Protein conserved in bacteria
FOB99_RS13195	COG3729	General stress protein
FOB99_RS13210	COG0134	indole-3-glycerol-phosphate synthase activity
FOB99_RS13210	COG0135	phosphoribosylanthranilate isomerase activity
FOB99_RS13215	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB99_RS13215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB99_RS13220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB99_RS13230	COG0613	PHP domain protein
FOB99_RS13235	COG0009	L-threonylcarbamoyladenylate synthase
FOB99_RS13245	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FOB99_RS13250	COG1028	Short-chain dehydrogenase reductase Sdr
FOB99_RS13255	COG0616	signal peptide processing
FOB99_RS13265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB99_RS13270	COG0583	DNA-binding transcription factor activity
FOB99_RS13290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOB99_RS13300	COG0671	phosphoesterase, PA-phosphatase related
FOB99_RS13305	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FOB99_RS13310	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOB99_RS13320	COG0023	Translation Initiation Factor
FOB99_RS13330	COG1349	DNA-binding transcription factor activity
FOB99_RS13350	COG5001	Diguanylate cyclase
FOB99_RS13365	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB99_RS13365	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB99_RS13370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB99_RS13375	COG2852	Protein conserved in bacteria
FOB99_RS13380	COG4172	Belongs to the ABC transporter superfamily
FOB99_RS13385	COG4172	Belongs to the ABC transporter superfamily
FOB99_RS13390	COG4171	peptide transport system, permease
FOB99_RS13395	COG4168	peptide transport system, permease
FOB99_RS13400	COG4166	transmembrane transport
FOB99_RS13410	COG0531	amino acid
FOB99_RS13420	COG0174	glutamine synthetase
FOB99_RS13430	COG1917	Cupin 2, conserved barrel domain protein
FOB99_RS13430	COG1396	sequence-specific DNA binding
FOB99_RS13435	COG1012	belongs to the aldehyde dehydrogenase family
FOB99_RS13440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB99_RS13445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB99_RS13450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOB99_RS13455	COG1842	Phage shock protein A
FOB99_RS13465	COG1983	PspC domain protein
FOB99_RS13475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB99_RS13480	COG0366	Alpha amylase catalytic
FOB99_RS13500	COG1175	transmembrane transport
FOB99_RS13505	COG0395	ABC-type sugar transport system, permease component
FOB99_RS13510	COG1063	alcohol dehydrogenase
FOB99_RS13520	COG0673	inositol 2-dehydrogenase activity
FOB99_RS13525	COG0673	inositol 2-dehydrogenase activity
FOB99_RS13530	COG1554	hydrolase, family 65, central catalytic
FOB99_RS13535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB99_RS13550	COG1609	Transcriptional regulator
FOB99_RS13555	COG3106	COG3106 Predicted ATPase
FOB99_RS13565	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FOB99_RS13570	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOB99_RS13575	COG4948	Mandelate Racemase Muconate Lactonizing
FOB99_RS13580	COG2866	Carboxypeptidase
FOB99_RS13585	COG0702	epimerase
FOB99_RS13595	COG3547	Transposase (IS116 IS110 IS902 family)
FOB99_RS13605	COG1073	alpha beta
FOB99_RS13610	COG0583	DNA-binding transcription factor activity
FOB99_RS13635	COG1484	DNA-dependent DNA replication
FOB99_RS13685	COG3716	PTS system mannose fructose sorbose family IID component
FOB99_RS13690	COG3715	PTS system
FOB99_RS13695	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS13695	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB99_RS13700	COG1253	flavin adenine dinucleotide binding
FOB99_RS13705	COG2200	EAL domain
FOB99_RS13710	COG1760	l-serine dehydratase
FOB99_RS13720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB99_RS13735	COG0251	oxidation-reduction process
FOB99_RS13740	COG1199	ATP-dependent helicase activity
FOB99_RS13745	COG1214	PFAM Peptidase M22, glycoprotease
FOB99_RS13750	COG3065	identical protein binding
FOB99_RS13755	COG0318	PFAM AMP-dependent synthetase and ligase
FOB99_RS13760	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FOB99_RS13765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB99_RS13770	COG4638	Rieske (2fe-2S)
FOB99_RS13810	COG2199	diguanylate cyclase activity
FOB99_RS13810	COG2203	Gaf domain
FOB99_RS13815	COG3042	response to heat
FOB99_RS13820	COG3189	MarR family transcriptional regulator
FOB99_RS13845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB99_RS13850	COG2199	diguanylate cyclase activity
FOB99_RS13865	COG3713	MltA-interacting MipA family protein
FOB99_RS13870	COG0656	L-ascorbic acid biosynthetic process
FOB99_RS13875	COG0676	glucose-6-phosphate 1-epimerase activity
FOB99_RS13880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB99_RS13890	COG3139	Protein of unknown function (DUF1315)
FOB99_RS13895	COG1063	alcohol dehydrogenase
FOB99_RS13900	COG2271	Major facilitator Superfamily
FOB99_RS13910	COG0191	fructose-bisphosphate aldolase activity
FOB99_RS13915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB99_RS13920	COG0667	Aldo Keto reductase
FOB99_RS13925	COG1349	DNA-binding transcription factor activity
FOB99_RS13930	COG2814	Major facilitator Superfamily
FOB99_RS13935	COG1335	isochorismatase
FOB99_RS13940	COG0252	asparaginase activity
FOB99_RS13945	COG0616	signal peptide processing
FOB99_RS13950	COG0778	Nitroreductase
FOB99_RS13960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB99_RS13970	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB99_RS13980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB99_RS13990	COG0494	nUDIX hydrolase
FOB99_RS13995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB99_RS14005	COG4136	ATPase activity
FOB99_RS14010	COG4135	transport system, permease component
FOB99_RS14015	COG4135	transport system, permease component
FOB99_RS14020	COG4135	transport system, permease component
FOB99_RS14030	COG3385	transposase activity
FOB99_RS14040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB99_RS14045	COG0398	Pfam SNARE associated Golgi protein
FOB99_RS14055	COG0398	Pfam SNARE associated Golgi protein
FOB99_RS14060	COG0708	Exodeoxyribonuclease III
FOB99_RS14095	COG3678	ATP-independent chaperone mediated protein folding
FOB99_RS14115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB99_RS14120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB99_RS14130	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB99_RS14160	COG0753	catalase activity
FOB99_RS14185	COG1988	membrane-bound metal-dependent
FOB99_RS14190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB99_RS14200	COG3001	Fructosamine kinase
FOB99_RS14210	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB99_RS14215	COG3137	Salt-induced outer membrane protein
FOB99_RS14285	COG0386	Belongs to the glutathione peroxidase family
FOB99_RS14295	COG0791	NLP P60 protein
FOB99_RS14300	COG2200	EAL domain
FOB99_RS14310	COG4256	Hemin uptake protein
FOB99_RS14325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB99_RS14325	COG0574	Belongs to the PEP-utilizing enzyme family
FOB99_RS14330	COG0318	PFAM AMP-dependent synthetase and ligase
FOB99_RS14335	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FOB99_RS14340	COG0644	oxidoreductase
FOB99_RS14345	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOB99_RS14350	COG2086	electron transfer activity
FOB99_RS14355	COG2207	Transcriptional regulator
FOB99_RS14355	COG1917	Cupin 2, conserved barrel domain protein
FOB99_RS14365	COG3119	arylsulfatase activity
FOB99_RS14435	COG0484	heat shock protein binding
FOB99_RS14440	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FOB99_RS14445	COG1403	HNH endonuclease
FOB99_RS14465	COG2026	Addiction module toxin, RelE StbE family
FOB99_RS14470	COG3077	Addiction module antitoxin, RelB DinJ family
FOB99_RS14490	COG0246	Mannitol dehydrogenase
FOB99_RS14500	COG1802	Transcriptional regulator
FOB99_RS14510	COG0339	signal peptide processing
FOB99_RS14515	COG1546	Belongs to the CinA family
FOB99_RS14535	COG2814	Major facilitator Superfamily
FOB99_RS14540	COG0697	spore germination
FOB99_RS14550	COG4977	sequence-specific DNA binding
FOB99_RS14555	COG1846	Transcriptional regulator
FOB99_RS14575	COG1012	belongs to the aldehyde dehydrogenase family
FOB99_RS14590	COG2199	diguanylate cyclase activity
FOB99_RS14610	COG3781	membrane
FOB99_RS14680	COG4948	Mandelate Racemase Muconate Lactonizing
FOB99_RS14710	COG0243	molybdopterin cofactor binding
FOB99_RS14765	COG0243	molybdopterin cofactor binding
FOB99_RS14775	COG0437	4 iron, 4 sulfur cluster binding
FOB99_RS14780	COG3302	dmso reductase anchor subunit
FOB99_RS14785	COG3381	protein complex oligomerization
FOB99_RS14795	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOB99_RS14800	COG1940	carbohydrate kinase activity
FOB99_RS14805	COG0583	DNA-binding transcription factor activity
FOB99_RS14810	COG2814	Major facilitator Superfamily
FOB99_RS14815	COG2814	Major facilitator Superfamily
FOB99_RS14830	COG3591	Belongs to the peptidase S1B family
FOB99_RS14845	COG0628	permease
FOB99_RS14850	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOB99_RS14855	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOB99_RS14865	COG0531	amino acid
FOB99_RS14875	COG3136	membrane protein required for alginate biosynthesis
FOB99_RS14880	COG0745	RESPONSE REGULATOR receiver
FOB99_RS14890	COG2205	protein histidine kinase activity
FOB99_RS14905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB99_RS14905	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB99_RS14915	COG5339	Protein conserved in bacteria
FOB99_RS14930	COG3250	beta-galactosidase activity
FOB99_RS14935	COG1309	transcriptional regulator
FOB99_RS14955	COG1609	Transcriptional regulator
FOB99_RS14960	COG1263	PTS System
FOB99_RS14960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB99_RS14965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOB99_RS14975	COG0673	inositol 2-dehydrogenase activity
FOB99_RS15015	COG4659	FMN binding
FOB99_RS15025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB99_RS15030	COG3104	oligopeptide transport
FOB99_RS15035	COG0625	glutathione transferase activity
FOB99_RS15075	COG3133	Outer membrane lipoprotein
FOB99_RS15090	COG1566	PFAM secretion protein HlyD family protein
FOB99_RS15100	COG2032	superoxide dismutase activity
FOB99_RS15105	COG4989	oxidoreductase activity
FOB99_RS15110	COG3313	Fe-S protein
FOB99_RS15115	COG1309	transcriptional regulator
FOB99_RS15120	COG1902	pentaerythritol trinitrate reductase activity
FOB99_RS15125	COG0346	lactoylglutathione lyase activity
FOB99_RS15135	COG1201	RNA secondary structure unwinding
FOB99_RS15140	COG1201	RNA secondary structure unwinding
FOB99_RS15145	COG0675	Transposase, IS605 OrfB family
FOB99_RS15155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOB99_RS15160	COG0791	NLP P60 protein
FOB99_RS15165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB99_RS15170	COG2814	Major facilitator Superfamily
FOB99_RS15185	COG0583	DNA-binding transcription factor activity
FOB99_RS15190	COG2814	Major facilitator Superfamily
FOB99_RS15195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOB99_RS15200	COG0307	riboflavin synthase, alpha
FOB99_RS15210	COG3468	outer membrane autotransporter barrel domain protein
FOB99_RS15240	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FOB99_RS15245	COG0437	4 iron, 4 sulfur cluster binding
FOB99_RS15260	COG0437	4 iron, 4 sulfur cluster binding
FOB99_RS15275	COG0469	pyruvate kinase activity
FOB99_RS15280	COG4238	major outer membrane lipoprotein
FOB99_RS15285	COG1376	ErfK ybiS ycfS ynhG family protein
FOB99_RS15300	COG0719	Fe-S assembly protein
FOB99_RS15305	COG0396	ATPase activity
FOB99_RS15310	COG0719	Fe-S assembly protein
FOB99_RS15315	COG0316	Belongs to the HesB IscA family
FOB99_RS15325	COG2050	protein possibly involved in aromatic compounds catabolism
FOB99_RS15330	COG0247	lactate metabolic process
FOB99_RS15330	COG0277	FAD linked oxidase domain protein
FOB99_RS15335	COG0628	permease
FOB99_RS15350	COG0738	Major facilitator superfamily
FOB99_RS15355	COG2271	Major facilitator Superfamily
FOB99_RS15375	COG3119	arylsulfatase activity
FOB99_RS15380	COG0641	radical SAM
FOB99_RS15395	COG4771	TonB-dependent receptor
FOB99_RS15405	COG0612	Peptidase, M16
FOB99_RS15415	COG0076	glutamate decarboxylase activity
FOB99_RS15420	COG0531	amino acid
FOB99_RS15445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB99_RS15450	COG0444	Belongs to the ABC transporter superfamily
FOB99_RS15460	COG1764	response to oxidative stress
FOB99_RS15475	COG1064	alcohol dehydrogenase
FOB99_RS15480	COG3093	addiction module antidote protein HigA
FOB99_RS15485	COG2864	formate dehydrogenase
FOB99_RS15490	COG0437	4 iron, 4 sulfur cluster binding
FOB99_RS15500	COG0697	spore germination
FOB99_RS15515	COG4886	Leucine-rich repeat (LRR) protein
FOB99_RS15525	COG2223	nitrite transmembrane transporter activity
FOB99_RS15555	COG0668	transmembrane transport
FOB99_RS15560	COG4166	transmembrane transport
FOB99_RS15610	COG2372	response to copper ion
FOB99_RS15625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB99_RS15630	COG1770	oligopeptidase
FOB99_RS15635	COG2979	Protein of unknown function (DUF533)
FOB99_RS15655	COG0800	Aldolase
FOB99_RS15660	COG0129	dihydroxy-acid dehydratase activity
FOB99_RS15665	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOB99_RS15670	COG1737	Transcriptional regulator
FOB99_RS15675	COG0469	pyruvate kinase activity
FOB99_RS15685	COG0739	heme binding
FOB99_RS15690	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FOB99_RS15700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB99_RS15730	COG0217	transcriptional regulatory protein
FOB99_RS15735	COG0494	nUDIX hydrolase
FOB99_RS15745	COG1335	isochorismatase
FOB99_RS15750	COG3547	Transposase (IS116 IS110 IS902 family)
FOB99_RS15850	COG3547	Transposase (IS116 IS110 IS902 family)
FOB99_RS15880	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FOB99_RS15935	COG1801	Protein of unknown function DUF72
FOB99_RS15940	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FOB99_RS15955	COG0243	molybdopterin cofactor binding
FOB99_RS15960	COG3005	denitrification pathway
FOB99_RS15970	COG3102	Protein conserved in bacteria
FOB99_RS15980	COG3755	Protein conserved in bacteria
FOB99_RS16010	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOB99_RS16035	COG0745	RESPONSE REGULATOR receiver
FOB99_RS16045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOB99_RS16050	COG0840	transmembrane signaling receptor activity
FOB99_RS16055	COG0840	transmembrane signaling receptor activity
FOB99_RS16060	COG0835	chemotaxis
FOB99_RS16065	COG0643	Histidine kinase
FOB99_RS16065	COG2198	Histidine kinase
FOB99_RS16070	COG1360	Flagellar Motor Protein
FOB99_RS16075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOB99_RS16100	COG1877	trehalose-phosphatase activity
FOB99_RS16105	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB99_RS16120	COG1528	Iron-storage protein
FOB99_RS16140	COG1528	Iron-storage protein
FOB99_RS16150	COG0814	amino acid
FOB99_RS16155	COG3012	SEC-C Motif Domain Protein
FOB99_RS16155	COG3318	Belongs to the UPF0149 family
FOB99_RS16185	COG2197	response regulator
FOB99_RS16240	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOB99_RS16245	COG1516	flagellar protein fliS
FOB99_RS16255	COG0366	Alpha amylase catalytic
FOB99_RS16265	COG2391	methyltransferase activity
FOB99_RS16270	COG0425	Belongs to the sulfur carrier protein TusA family
FOB99_RS16300	COG1881	PFAM PEBP family protein
FOB99_RS16305	COG2076	Multidrug Resistance protein
FOB99_RS16320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB99_RS16325	COG1317	bacterial-type flagellum organization
FOB99_RS16330	COG1157	protein secretion by the type III secretion system
FOB99_RS16340	COG3144	bacterial-type flagellum assembly
FOB99_RS16345	COG1580	Controls the rotational direction of flagella during chemotaxis
FOB99_RS16350	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB99_RS16355	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB99_RS16360	COG3190	flagellar
FOB99_RS16365	COG1338	Plays a role in the flagellum-specific transport system
FOB99_RS16370	COG1987	bacterial-type flagellum assembly
FOB99_RS16375	COG1684	flagellar biosynthetic protein fliR
FOB99_RS16380	COG2197	response regulator
FOB99_RS16405	COG5475	Uncharacterized small protein (DUF2158)
FOB99_RS16410	COG2354	Protein conserved in bacteria
FOB99_RS16415	COG0697	spore germination
FOB99_RS16420	COG3727	T/G mismatch-specific endonuclease activity
FOB99_RS16425	COG0270	DNA (cytosine-5-)-methyltransferase activity
FOB99_RS16470	COG2205	protein histidine kinase activity
FOB99_RS16475	COG0745	RESPONSE REGULATOR receiver
FOB99_RS16480	COG2351	hydroxyisourate hydrolase activity
FOB99_RS16495	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOB99_RS16505	COG0500	methyltransferase
FOB99_RS16550	COG4386	tail sheath protein
FOB99_RS16575	COG3436	PFAM IS66 Orf2 family protein
FOB99_RS16615	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FOB99_RS16620	COG1403	HNH endonuclease
FOB99_RS16675	COG0477	Major facilitator Superfamily
FOB99_RS16690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB99_RS16715	COG0583	DNA-binding transcription factor activity
FOB99_RS16720	COG0583	DNA-binding transcription factor activity
FOB99_RS16730	COG1376	ErfK ybiS ycfS ynhG family protein
FOB99_RS16745	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FOB99_RS16775	COG1289	transmembrane transporter activity
FOB99_RS16800	COG4372	Transposase
FOB99_RS16840	COG3436	PFAM IS66 Orf2 family protein
FOB99_RS16850	COG0582	viral genome integration into host DNA
FOB99_RS16855	COG2925	Exonuclease
FOB99_RS16860	COG0425	Belongs to the sulfur carrier protein TusA family
FOB99_RS16865	COG2391	methyltransferase activity
FOB99_RS16870	COG0531	amino acid
FOB99_RS16880	COG0583	DNA-binding transcription factor activity
FOB99_RS16885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB99_RS16890	COG4115	mRNA cleavage
FOB99_RS17035	COG0438	transferase activity, transferring glycosyl groups
FOB99_RS17040	COG2327	Polysaccharide pyruvyl transferase
FOB99_RS17045	COG2244	polysaccharide biosynthetic process
FOB99_RS17050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB99_RS17055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB99_RS17060	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOB99_RS17060	COG0662	Cupin 2, conserved barrel domain protein
FOB99_RS17065	COG0297	glycogen (starch) synthase activity
FOB99_RS17070	COG1051	belongs to the nudix hydrolase family
FOB99_RS17075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB99_RS17080	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FOB99_RS17085	COG0110	maltose O-acetyltransferase activity
FOB99_RS17105	COG0438	transferase activity, transferring glycosyl groups
FOB99_RS17110	COG1045	serine acetyltransferase
FOB99_RS17120	COG0489	protein tyrosine kinase activity
FOB99_RS17120	COG3206	protein involved in exopolysaccharide biosynthesis
FOB99_RS17125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB99_RS17130	COG1596	polysaccharide export
FOB99_RS17145	COG2982	Protein involved in outer membrane biogenesis
FOB99_RS17155	COG0572	uridine kinase
FOB99_RS17185	COG2205	protein histidine kinase activity
FOB99_RS17190	COG0745	RESPONSE REGULATOR receiver
FOB99_RS17220	COG1063	alcohol dehydrogenase
FOB99_RS17230	COG3775	system Galactitol-specific IIC component
FOB99_RS17235	COG3414	Phosphotransferase system galactitol-specific IIB component
FOB99_RS17240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS17255	COG1830	Aldolase
FOB99_RS17265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB99_RS17270	COG2188	Transcriptional regulator
FOB99_RS17275	COG3757	hydrolase, family 25
FOB99_RS17280	COG0351	phosphomethylpyrimidine kinase
FOB99_RS17305	COG5455	response to cobalt ion
FOB99_RS17315	COG3188	usher protein
FOB99_RS17320	COG3121	Chaperone
FOB99_RS17325	COG3539	Fimbrial protein
FOB99_RS17340	COG0489	protein tyrosine kinase activity
FOB99_RS17385	COG0714	Associated with various cellular activities
FOB99_RS17390	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOB99_RS17395	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FOB99_RS17400	COG4715	Zinc finger, swim domain protein
FOB99_RS17410	COG4808	Protein conserved in bacteria
FOB99_RS17435	COG3275	phosphorelay sensor kinase activity
FOB99_RS17460	COG0500	methyltransferase
FOB99_RS17475	COG5301	cellulose 1,4-beta-cellobiosidase activity
FOB99_RS17500	COG0789	Transcriptional regulator
FOB99_RS17520	COG1174	glycine betaine transport
FOB99_RS17525	COG1125	glycine betaine transport
FOB99_RS17530	COG1174	glycine betaine transport
FOB99_RS17535	COG1732	Glycine betaine
FOB99_RS17540	COG1472	Belongs to the glycosyl hydrolase 3 family
FOB99_RS17545	COG0277	FAD linked oxidase domain protein
FOB99_RS17550	COG1686	Belongs to the peptidase S11 family
FOB99_RS17560	COG0586	Pfam SNARE associated Golgi protein
FOB99_RS17590	COG1346	cytolysis
FOB99_RS17600	COG2949	membrane
FOB99_RS17610	COG0493	'glutamate synthase
FOB99_RS17620	COG4211	Belongs to the binding-protein-dependent transport system permease family
FOB99_RS17625	COG1129	ABC transporter
FOB99_RS17630	COG1879	ABC-type sugar transport system periplasmic component
FOB99_RS17635	COG1609	Transcriptional regulator
FOB99_RS17640	COG2311	Membrane
FOB99_RS17660	COG0833	amino acid
FOB99_RS17665	COG0583	DNA-binding transcription factor activity
FOB99_RS17670	COG2855	membrane
FOB99_RS17680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB99_RS17680	COG1522	sequence-specific DNA binding
FOB99_RS17685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB99_RS17700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB99_RS17705	COG2313	pseudouridylate synthase activity
FOB99_RS17710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB99_RS17715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS17715	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOB99_RS17715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS17720	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB99_RS17725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS17725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS17730	COG2814	Major facilitator Superfamily
FOB99_RS17750	COG0246	Mannitol dehydrogenase
FOB99_RS17755	COG0523	cobalamin synthesis protein
FOB99_RS17760	COG0671	phosphoesterase, PA-phosphatase related
FOB99_RS17765	COG0791	NLP P60 protein
FOB99_RS17770	COG2200	EAL domain
FOB99_RS17775	COG4166	transmembrane transport
FOB99_RS17780	COG4174	ABC transporter (Permease)
FOB99_RS17785	COG4239	(ABC) transporter, permease
FOB99_RS17790	COG4172	Belongs to the ABC transporter superfamily
FOB99_RS17800	COG2814	Major facilitator Superfamily
FOB99_RS17805	COG1187	pseudouridine synthase activity
FOB99_RS17810	COG1061	Type III restriction enzyme res subunit
FOB99_RS17830	COG3083	sulfuric ester hydrolase activity
FOB99_RS17840	COG3468	outer membrane autotransporter barrel domain protein
FOB99_RS17845	COG2197	response regulator
FOB99_RS17850	COG4235	cytochrome complex assembly
FOB99_RS17850	COG3088	subunit of a heme lyase
FOB99_RS17855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB99_RS17860	COG1138	Cytochrome C-type biogenesis protein
FOB99_RS17870	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB99_RS17875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB99_RS17880	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB99_RS17890	COG3005	denitrification pathway
FOB99_RS17895	COG3043	anaerobic respiration
FOB99_RS17900	COG0348	domain, Protein
FOB99_RS17905	COG0437	4 iron, 4 sulfur cluster binding
FOB99_RS17915	COG3062	negative regulation of establishment of protein localization
FOB99_RS17920	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB99_RS17920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB99_RS17940	COG4615	Cyclic peptide transporter
FOB99_RS17945	COG3145	DNA-N1-methyladenine dioxygenase activity
FOB99_RS17950	COG2169	Transcriptional regulator
FOB99_RS17950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB99_RS17955	COG1477	protein flavinylation
FOB99_RS17965	COG0642	Histidine kinase
FOB99_RS17965	COG2198	Histidine kinase
FOB99_RS17970	COG2197	response regulator
FOB99_RS17975	COG2205	protein histidine kinase activity
FOB99_RS17975	COG0784	Response regulator, receiver
FOB99_RS17980	COG4676	Protein conserved in bacteria
FOB99_RS17985	COG5445	Predicted secreted protein (DUF2300)
FOB99_RS18015	COG3234	Protein of unknown function (DUF1175)
FOB99_RS18025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOB99_RS18035	COG3468	outer membrane autotransporter barrel domain protein
FOB99_RS18040	COG3468	outer membrane autotransporter barrel domain protein
FOB99_RS18050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB99_RS18055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB99_RS18060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB99_RS18065	COG3642	lipopolysaccharide core region biosynthetic process
FOB99_RS18075	COG0584	glycerophosphoryl diester phosphodiesterase
FOB99_RS18080	COG2271	Major facilitator Superfamily
FOB99_RS18085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOB99_RS18095	COG0247	lactate metabolic process
FOB99_RS18100	COG5464	transposase or invertase
FOB99_RS18170	COG0318	PFAM AMP-dependent synthetase and ligase
FOB99_RS18180	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOB99_RS18195	COG1169	isochorismate synthase
FOB99_RS18200	COG4575	ribosome binding
FOB99_RS18205	COG2153	protein acetylation
FOB99_RS18245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB99_RS18250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB99_RS18260	COG0839	Belongs to the complex I subunit 6 family
FOB99_RS18280	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FOB99_RS18285	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FOB99_RS18305	COG0583	DNA-binding transcription factor activity
FOB99_RS18310	COG0436	Aminotransferase
FOB99_RS18320	COG0471	metal ion transport
FOB99_RS18320	COG0490	domain, Protein
FOB99_RS18325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB99_RS18340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB99_RS18345	COG0857	belongs to the CobB CobQ family
FOB99_RS18345	COG0280	phosphate acetyltransferase
FOB99_RS18350	COG1288	antiporter activity
FOB99_RS18360	COG0622	Phosphoesterase
FOB99_RS18365	COG0625	glutathione transferase activity
FOB99_RS18370	COG0625	glutathione transferase activity
FOB99_RS18375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOB99_RS18380	COG1090	epimerase
FOB99_RS18385	COG5464	transposase or invertase
FOB99_RS18390	COG4598	ABC transporter
FOB99_RS18395	COG4160	amino acid transport
FOB99_RS18400	COG4215	(ABC) transporter
FOB99_RS18405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB99_RS18410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB99_RS18415	COG0163	prenyltransferase activity
FOB99_RS18420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOB99_RS18425	COG1286	toxin biosynthetic process
FOB99_RS18430	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FOB99_RS18435	COG0285	dihydrofolate synthase activity
FOB99_RS18445	COG0586	Pfam SNARE associated Golgi protein
FOB99_RS18455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB99_RS18475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB99_RS18490	COG3101	peptidyl-lysine hydroxylation
FOB99_RS18495	COG0730	response to heat
FOB99_RS18525	COG3539	Fimbrial protein
FOB99_RS18530	COG3539	Fimbrial protein
FOB99_RS18535	COG3539	Fimbrial protein
FOB99_RS18550	COG3539	Fimbrial protein
FOB99_RS18560	COG2062	phosphohistidine phosphatase, SixA
FOB99_RS18575	COG3691	Protein conserved in bacteria
FOB99_RS18610	COG0582	viral genome integration into host DNA
FOB99_RS18645	COG0477	Major facilitator Superfamily
FOB99_RS18650	COG1566	PFAM secretion protein HlyD family protein
FOB99_RS18655	COG2197	response regulator
FOB99_RS18660	COG2205	protein histidine kinase activity
FOB99_RS18660	COG2198	Histidine kinase
FOB99_RS18660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB99_RS18660	COG0784	Response regulator, receiver
FOB99_RS18665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB99_RS18670	COG0679	Auxin Efflux Carrier
FOB99_RS18675	COG0028	Belongs to the TPP enzyme family
FOB99_RS18700	COG1560	Kdo2-lipid A biosynthetic process
FOB99_RS18710	COG0436	Aminotransferase
FOB99_RS18720	COG3279	Response regulator of the LytR AlgR family
FOB99_RS18735	COG1363	Peptidase, m42
FOB99_RS18745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB99_RS18775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB99_RS18795	COG3415	Transposase
FOB99_RS18800	COG3415	Transposase
FOB99_RS18835	COG0583	DNA-binding transcription factor activity
FOB99_RS18840	COG0385	Bile acid
FOB99_RS18845	COG3530	Putative quorum-sensing-regulated virulence factor
FOB99_RS18865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB99_RS18870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS18875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB99_RS18880	COG2190	(PTS) system
FOB99_RS18900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB99_RS18910	COG4208	sulfate ABC transporter
FOB99_RS18915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FOB99_RS18920	COG4150	thiosulfate binding
FOB99_RS18925	COG1028	Short-chain dehydrogenase reductase Sdr
FOB99_RS18945	COG2837	iron assimilation
FOB99_RS18965	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOB99_RS18980	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOB99_RS18985	COG4816	utilization protein
FOB99_RS19020	COG0076	glutamate decarboxylase activity
FOB99_RS19025	COG0076	glutamate decarboxylase activity
FOB99_RS19030	COG0531	amino acid
FOB99_RS19035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOB99_RS19045	COG4819	ethanolamine utilization protein
FOB99_RS19050	COG4917	ethanolamine utilization protein
FOB99_RS19055	COG4810	utilization protein
FOB99_RS19060	COG0280	phosphate acetyltransferase
FOB99_RS19060	COG0281	malic enzyme
FOB99_RS19070	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB99_RS19075	COG5342	invasion associated locus B
FOB99_RS19085	COG0493	'glutamate synthase
FOB99_RS19085	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB99_RS19095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB99_RS19105	COG1393	Belongs to the ArsC family
FOB99_RS19120	COG0400	carboxylic ester hydrolase activity
FOB99_RS19130	COG2321	neutral zinc metallopeptidase
FOB99_RS19140	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOB99_RS19150	COG2716	regulation of RNA biosynthetic process
FOB99_RS19155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOB99_RS19160	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB99_RS19170	COG0650	Formate hydrogenlyase subunit 4
FOB99_RS19175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB99_RS19180	COG4237	Hydrogenase 4 membrane
FOB99_RS19185	COG0651	ATP synthesis coupled electron transport
FOB99_RS19195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB99_RS19200	COG3260	NADH ubiquinone oxidoreductase 20
FOB99_RS19210	COG3604	Transcriptional regulator
FOB99_RS19215	COG3604	Transcriptional regulator
FOB99_RS19225	COG0628	permease
FOB99_RS19230	COG4783	chaperone-mediated protein folding
FOB99_RS19235	COG1393	Belongs to the ArsC family
FOB99_RS19245	COG2233	PERMEase
FOB99_RS19260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB99_RS19265	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOB99_RS19270	COG0248	Ppx GppA phosphatase
FOB99_RS19275	COG2200	EAL domain
FOB99_RS19300	COG3133	Outer membrane lipoprotein
FOB99_RS19315	COG0516	GMP reductase activity
FOB99_RS19315	COG0517	IMP dehydrogenase activity
FOB99_RS19325	COG1645	bacterial-type flagellum-dependent swarming motility
FOB99_RS19340	COG2976	Protein conserved in bacteria
FOB99_RS19375	COG3547	Transposase (IS116 IS110 IS902 family)
FOB99_RS19395	COG2975	iron-sulfur cluster assembly
FOB99_RS19400	COG0633	Ferredoxin
FOB99_RS19420	COG0822	iron-sulfur transferase activity
FOB99_RS19440	COG0483	inositol monophosphate 1-phosphatase activity
FOB99_RS19445	COG1073	alpha beta
FOB99_RS19450	COG3711	transcriptional antiterminator
FOB99_RS19455	COG2814	Major facilitator Superfamily
FOB99_RS19460	COG0583	DNA-binding transcription factor activity
FOB99_RS19490	COG2259	Doxx family
FOB99_RS19495	COG2017	converts alpha-aldose to the beta-anomer
FOB99_RS19500	COG1063	alcohol dehydrogenase
FOB99_RS19505	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB99_RS19510	COG1129	ABC transporter
FOB99_RS19520	COG0457	Tetratricopeptide repeat
FOB99_RS19525	COG0457	Tetratricopeptide repeat
FOB99_RS19530	COG1940	carbohydrate kinase activity
FOB99_RS19545	COG0347	Belongs to the P(II) protein family
FOB99_RS19550	COG2204	response regulator
FOB99_RS19555	COG3170	Tfp pilus assembly protein FimV
FOB99_RS19560	COG2205	protein histidine kinase activity
FOB99_RS19580	COG0560	Phosphoserine phosphatase
FOB99_RS19585	COG1737	Transcriptional regulator
FOB99_RS19605	COG5301	cellulose 1,4-beta-cellobiosidase activity
FOB99_RS19650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB99_RS19685	COG0681	Belongs to the peptidase S26 family
FOB99_RS19695	COG3086	response to oxidative stress
FOB99_RS19700	COG3026	antisigma factor binding
FOB99_RS19705	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FOB99_RS19710	COG1595	DNA-templated transcription, initiation
FOB99_RS19730	COG0513	Belongs to the DEAD box helicase family
FOB99_RS19735	COG0583	DNA-binding transcription factor activity
FOB99_RS19755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB99_RS19760	COG3118	belongs to the thioredoxin family
FOB99_RS19770	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB99_RS19770	COG1042	CoA-binding domain protein
FOB99_RS19770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB99_RS19775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB99_RS19780	COG5544	Lipoprotein
FOB99_RS19785	COG0477	Major facilitator Superfamily
FOB99_RS19810	COG3385	transposase activity
FOB99_RS19815	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB99_RS19820	COG0564	pseudouridine synthase activity
FOB99_RS19830	COG0542	response to heat
FOB99_RS19835	COG3385	transposase activity
FOB99_RS19840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB99_RS19850	COG1605	Chorismate mutase
FOB99_RS19850	COG0077	Prephenate dehydratase
FOB99_RS19855	COG0287	Prephenate dehydrogenase
FOB99_RS19855	COG1605	Chorismate mutase
FOB99_RS19860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB99_RS19880	COG2885	chlorophyll binding
FOB99_RS19905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB99_RS19910	COG4137	Cytochrome C assembly protein
FOB99_RS19915	COG4536	flavin adenine dinucleotide binding
FOB99_RS19930	COG0497	DNA recombination
FOB99_RS19935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB99_RS19945	COG2867	negative regulation of translational initiation
FOB99_RS19960	COG0582	viral genome integration into host DNA
FOB99_RS19980	COG0366	Alpha amylase catalytic
FOB99_RS19990	COG0579	oxidoreductase
FOB99_RS20005	COG1113	amino acid transport
FOB99_RS20010	COG1802	Transcriptional regulator
FOB99_RS20015	COG1652	LysM domain
FOB99_RS20020	COG0401	homolog of Blt101
FOB99_RS20030	COG0640	Transcriptional regulator
FOB99_RS20035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB99_RS20040	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOB99_RS20055	COG4575	ribosome binding
FOB99_RS20060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB99_RS20070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB99_RS20075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB99_RS20080	COG4175	Glycine betaine
FOB99_RS20085	COG4176	ABC-type proline glycine betaine transport system permease component
FOB99_RS20090	COG2113	Glycine betaine
FOB99_RS20100	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOB99_RS20110	COG1846	Transcriptional regulator
FOB99_RS20120	COG2814	Major facilitator Superfamily
FOB99_RS20135	COG1238	metal cluster binding
FOB99_RS20140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB99_RS20170	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FOB99_RS20190	COG1546	Belongs to the CinA family
FOB99_RS20195	COG2951	lytic endotransglycosylase activity
FOB99_RS20205	COG3732	PTS system glucitol sorbitol-specific
FOB99_RS20215	COG1028	Short-chain dehydrogenase reductase Sdr
FOB99_RS20220	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS20225	COG1349	DNA-binding transcription factor activity
FOB99_RS20250	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOB99_RS20255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB99_RS20260	COG1609	Transcriptional regulator
FOB99_RS20265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB99_RS20270	COG3261	NADH dehydrogenase
FOB99_RS20270	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FOB99_RS20275	COG0650	Formate hydrogenlyase subunit 4
FOB99_RS20280	COG0651	ATP synthesis coupled electron transport
FOB99_RS20285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB99_RS20295	COG0375	protein maturation
FOB99_RS20300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOB99_RS20305	COG0298	carbon dioxide binding
FOB99_RS20310	COG0409	Hydrogenase expression formation protein
FOB99_RS20315	COG0309	Hydrogenase expression formation protein (HypE)
FOB99_RS20320	COG3604	Transcriptional regulator
FOB99_RS20350	COG1349	DNA-binding transcription factor activity
FOB99_RS20380	COG3423	Transcriptional regulator
FOB99_RS20410	COG1388	LysM domain
FOB99_RS20410	COG4942	peptidase
FOB99_RS20465	COG2234	aminopeptidase activity
FOB99_RS20495	COG0720	synthase
FOB99_RS20500	COG0644	oxidoreductase
FOB99_RS20505	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FOB99_RS20515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOB99_RS20520	COG2086	electron transfer activity
FOB99_RS20525	COG0477	Major facilitator Superfamily
FOB99_RS20530	COG0277	FAD linked oxidase domain protein
FOB99_RS20540	COG0602	queuosine metabolic process
FOB99_RS20570	COG3956	TIGRFAM MazG family protein
FOB99_RS20575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB99_RS20590	COG4948	Mandelate Racemase Muconate Lactonizing
FOB99_RS20595	COG4948	Mandelate Racemase Muconate Lactonizing
FOB99_RS20600	COG2271	Major facilitator Superfamily
FOB99_RS20605	COG0716	FMN binding
FOB99_RS20610	COG0564	pseudouridine synthase activity
FOB99_RS20615	COG3098	single-species biofilm formation
FOB99_RS20630	COG1611	Belongs to the LOG family
FOB99_RS20635	COG3385	transposase activity
FOB99_RS20640	COG0814	amino acid
FOB99_RS20645	COG1760	l-serine dehydratase
FOB99_RS20655	COG1454	alcohol dehydrogenase
FOB99_RS20660	COG0235	Class ii aldolase
FOB99_RS20665	COG0738	Major facilitator superfamily
FOB99_RS20685	COG1349	DNA-binding transcription factor activity
FOB99_RS20695	COG2363	Small membrane protein
FOB99_RS20700	COG0583	DNA-binding transcription factor activity
FOB99_RS20710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOB99_RS20715	COG2166	iron-sulfur cluster assembly
FOB99_RS20720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOB99_RS20725	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOB99_RS20740	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOB99_RS20750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB99_RS20755	COG1074	ATP-dependent DNA helicase activity
FOB99_RS20765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOB99_RS20770	COG4967	type IV pilus modification protein PilV
FOB99_RS20780	COG4795	General secretion pathway protein
FOB99_RS20800	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FOB99_RS20815	COG0861	Integral membrane protein TerC family
FOB99_RS20825	COG0667	Aldo Keto reductase
FOB99_RS20840	COG1609	Transcriptional regulator
FOB99_RS20850	COG0583	DNA-binding transcription factor activity
FOB99_RS20855	COG1794	racemase activity, acting on amino acids and derivatives
FOB99_RS20860	COG2814	Major facilitator Superfamily
FOB99_RS20865	COG1028	Short-chain dehydrogenase reductase Sdr
FOB99_RS20875	COG0183	Belongs to the thiolase family
FOB99_RS20930	COG4942	peptidase
FOB99_RS20935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOB99_RS20940	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FOB99_RS20945	COG2080	2 iron, 2 sulfur cluster binding
FOB99_RS20965	COG2233	PERMEase
FOB99_RS20995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB99_RS21000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB99_RS21010	COG0716	FMN binding
FOB99_RS21030	COG1272	protein, Hemolysin III
FOB99_RS21040	COG2723	6-phospho-beta-galactosidase activity
FOB99_RS21045	COG1028	Short-chain dehydrogenase reductase Sdr
FOB99_RS21070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB99_RS21075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB99_RS21080	COG0006	proline dipeptidase activity
FOB99_RS21100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB99_RS21115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB99_RS21130	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOB99_RS21130	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOB99_RS21135	COG1703	isobutyryl-CoA mutase activity
FOB99_RS21140	COG1024	Enoyl-CoA hydratase
FOB99_RS21145	COG0427	acetyl-CoA hydrolase
FOB99_RS21150	COG0427	acetyl-CoA hydrolase
FOB99_RS21160	COG2968	Membrane
FOB99_RS21170	COG0668	transmembrane transport
FOB99_RS21175	COG0191	fructose-bisphosphate aldolase activity
FOB99_RS21210	COG1122	ATPase activity
FOB99_RS21215	COG1122	ATPase activity
FOB99_RS21220	COG1072	(Pantothenic acid kinase))
FOB99_RS21230	COG1494	fructose-1,6-bisphosphatase
FOB99_RS21235	COG1063	alcohol dehydrogenase
FOB99_RS21245	COG0330	HflC and HflK could
FOB99_RS21250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB99_RS21255	COG0501	Belongs to the peptidase M48B family
FOB99_RS21295	COG2814	Major facilitator Superfamily
FOB99_RS21305	COG2356	endonuclease I
FOB99_RS21310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB99_RS21330	COG2805	Type II/IV secretion system protein
FOB99_RS21335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB99_RS21340	COG0762	integral membrane protein
FOB99_RS21355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB99_RS21365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB99_RS21385	COG0252	asparaginase activity
FOB99_RS21395	COG3171	Protein conserved in bacteria
FOB99_RS21405	COG1194	a g-specific adenine glycosylase
FOB99_RS21420	COG2211	Major facilitator Superfamily
FOB99_RS21425	COG1982	Orn Lys Arg decarboxylase major
FOB99_RS21430	COG1811	Na channel or pump
FOB99_RS21440	COG0582	viral genome integration into host DNA
FOB99_RS21445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB99_RS21445	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FOB99_RS21470	COG3468	outer membrane autotransporter barrel domain protein
FOB99_RS21510	COG3344	reverse transcriptase
FOB99_RS21585	COG3468	outer membrane autotransporter barrel domain protein
FOB99_RS21590	COG2020	methyltransferase activity
FOB99_RS21615	COG2003	Belongs to the UPF0758 family
FOB99_RS21680	COG1620	l-lactate permease
FOB99_RS21690	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FOB99_RS21700	COG0277	FAD linked oxidase domain protein
FOB99_RS21710	COG2186	Transcriptional regulator
FOB99_RS21720	COG0318	PFAM AMP-dependent synthetase and ligase
FOB99_RS21730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB99_RS21745	COG0795	lipopolysaccharide-transporting ATPase activity
FOB99_RS21750	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOB99_RS21760	COG2244	polysaccharide biosynthetic process
FOB99_RS21765	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOB99_RS21770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOB99_RS21775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOB99_RS21780	COG0306	phosphate transporter
FOB99_RS21785	COG0754	glutathionylspermidine amidase activity
FOB99_RS21790	COG0625	glutathione transferase activity
FOB99_RS21795	COG0298	carbon dioxide binding
FOB99_RS21805	COG1773	rubredoxin
FOB99_RS21810	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOB99_RS21815	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FOB99_RS21820	COG5557	Pfam Polysulphide reductase, NrfD
FOB99_RS21825	COG0437	4 iron, 4 sulfur cluster binding
FOB99_RS21830	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FOB99_RS21845	COG0667	Aldo Keto reductase
FOB99_RS21855	COG1028	Short-chain dehydrogenase reductase Sdr
FOB99_RS21860	COG0848	biopolymer transport protein
FOB99_RS21865	COG0811	peptide transport
FOB99_RS21870	COG0626	cystathionine gamma-synthase activity
FOB99_RS21875	COG0586	Pfam SNARE associated Golgi protein
FOB99_RS21880	COG2207	Transcriptional regulator
FOB99_RS21885	COG1979	alcohol dehydrogenase
FOB99_RS21890	COG0656	L-ascorbic acid biosynthetic process
FOB99_RS21900	COG4238	major outer membrane lipoprotein
FOB99_RS21910	COG2132	Multicopper oxidase
FOB99_RS21915	COG0204	Acyl-transferase
FOB99_RS21920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOB99_RS21925	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOB99_RS21930	COG3111	PFAM Bacterial OB fold (BOF) protein
FOB99_RS21935	COG0745	RESPONSE REGULATOR receiver
FOB99_RS21940	COG0642	Histidine kinase
FOB99_RS21950	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB99_RS21955	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOB99_RS21960	COG0187	DNA topoisomerase II activity
FOB99_RS21965	COG3150	esterase
FOB99_RS21970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOB99_RS21975	COG3151	Protein conserved in bacteria
FOB99_RS21980	COG0494	nUDIX hydrolase
FOB99_RS21985	COG1538	Outer membrane efflux protein
FOB99_RS21995	COG0754	glutathionylspermidine amidase activity
FOB99_RS22000	COG3384	dioxygenase
FOB99_RS22020	COG2960	long-chain fatty acid transporting porin activity
FOB99_RS22055	COG2268	Band 7 protein
FOB99_RS22080	COG3025	triphosphatase activity
FOB99_RS22090	COG4991	sh3 domain protein
FOB99_RS22105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOB99_RS22125	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB99_RS22140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOB99_RS22145	COG0358	DNA primase activity
FOB99_RS22150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB99_RS22155	COG3385	transposase activity
FOB99_RS22175	COG1695	Transcriptional regulator
FOB99_RS22195	COG1609	Transcriptional regulator
FOB99_RS22200	COG3250	beta-galactosidase activity
FOB99_RS22205	COG2731	YhcH YjgK YiaL family protein
FOB99_RS22210	COG0531	amino acid
FOB99_RS22230	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FOB99_RS22230	COG3408	Glycogen debranching enzyme
FOB99_RS22235	COG1902	pentaerythritol trinitrate reductase activity
FOB99_RS22235	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB99_RS22240	COG5499	transcription regulator containing HTH domain
FOB99_RS22245	COG4680	protein conserved in bacteria
FOB99_RS22255	COG1451	nucleotide metabolic process
FOB99_RS22260	COG2949	membrane
FOB99_RS22265	COG0673	inositol 2-dehydrogenase activity
FOB99_RS22270	COG0861	Integral membrane protein TerC family
FOB99_RS22285	COG2721	sulfolactate sulfo-lyase activity
FOB99_RS22295	COG2271	Major facilitator Superfamily
FOB99_RS22315	COG2186	Transcriptional regulator
FOB99_RS22320	COG0586	Pfam SNARE associated Golgi protein
FOB99_RS22335	COG4575	ribosome binding
FOB99_RS22340	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FOB99_RS22350	COG2259	Doxx family
FOB99_RS22355	COG0435	Glutathione S-transferase
FOB99_RS22360	COG3152	Membrane
FOB99_RS22365	COG0583	DNA-binding transcription factor activity
FOB99_RS22370	COG1741	Belongs to the pirin family
FOB99_RS22385	COG0814	amino acid
FOB99_RS22390	COG1760	l-serine dehydratase
FOB99_RS22395	COG0251	oxidation-reduction process
FOB99_RS22400	COG1882	Formate acetyltransferase
FOB99_RS22405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB99_RS22415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB99_RS22420	COG0583	DNA-binding transcription factor activity
FOB99_RS22450	COG1929	Belongs to the glycerate kinase type-1 family
FOB99_RS22455	COG2084	Dehydrogenase
FOB99_RS22465	COG2271	Major facilitator Superfamily
FOB99_RS22470	COG2721	sulfolactate sulfo-lyase activity
FOB99_RS22475	COG1349	DNA-binding transcription factor activity
FOB99_RS22485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB99_RS22495	COG3716	PTS system mannose fructose sorbose family IID component
FOB99_RS22500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB99_RS22520	COG3715	PTS system
FOB99_RS22525	COG3716	PTS system mannose fructose sorbose family IID component
FOB99_RS22530	COG0363	glucosamine-6-phosphate deaminase activity
FOB99_RS22550	COG3121	Chaperone
FOB99_RS22570	COG3539	Fimbrial protein
FOB99_RS22575	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOB99_RS22595	COG2823	Periplasmic or secreted lipoprotein
FOB99_RS22600	COG0701	Predicted permease
FOB99_RS22605	COG0702	epimerase
FOB99_RS22610	COG0693	protein deglycase activity
FOB99_RS22625	COG3153	acetyltransferase
FOB99_RS22630	COG3154	lipid carrier protein
FOB99_RS22635	COG0826	peptidase U32
FOB99_RS22640	COG0826	peptidase U32
FOB99_RS22645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB99_RS22650	COG0814	amino acid
FOB99_RS22655	COG0513	Belongs to the DEAD box helicase family
FOB99_RS22715	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)