locus-tag	class	description
MC63_RS00010	COG1414	Transcriptional regulator
MC63_RS00025	COG2224	Isocitrate lyase
MC63_RS00030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MC63_RS00040	COG0456	acetyltransferase
MC63_RS00070	COG0151	Belongs to the GarS family
MC63_RS00075	COG2204	response regulator
MC63_RS00080	COG4191	Histidine kinase
MC63_RS00085	COG3678	ATP-independent chaperone mediated protein folding
MC63_RS00100	COG3068	Protein conserved in bacteria
MC63_RS00135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MC63_RS00140	COG2104	thiamine diphosphate biosynthetic process
MC63_RS00150	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MC63_RS00185	COG0250	Participates in transcription elongation, termination and antitermination
MC63_RS00190	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MC63_RS00225	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MC63_RS00225	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MC63_RS00255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MC63_RS00260	COG4206	TonB-dependent receptor
MC63_RS00275	COG1309	transcriptional regulator
MC63_RS00285	COG0583	DNA-binding transcription factor activity
MC63_RS00305	COG4948	Mandelate Racemase Muconate Lactonizing
MC63_RS00310	COG3385	transposase activity
MC63_RS00340	COG2194	sulfuric ester hydrolase activity
MC63_RS00345	COG2207	Transcriptional regulator
MC63_RS00350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MC63_RS00355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MC63_RS00360	COG1882	Formate acetyltransferase
MC63_RS00365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MC63_RS00370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MC63_RS00375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS00375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MC63_RS00375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS00380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MC63_RS00390	COG3738	Protein conserved in bacteria
MC63_RS00395	COG0697	spore germination
MC63_RS00405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MC63_RS00410	COG0460	homoserine dehydrogenase
MC63_RS00410	COG0527	aspartate kinase activity
MC63_RS00415	COG0626	cystathionine gamma-synthase activity
MC63_RS00425	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MC63_RS00435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MC63_RS00440	COG1609	Transcriptional regulator
MC63_RS00445	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MC63_RS00460	COG1575	Belongs to the MenA family. Type 1 subfamily
MC63_RS00470	COG3074	FtsZ-dependent cytokinesis
MC63_RS00485	COG1494	fructose-1,6-bisphosphatase
MC63_RS00495	COG0589	response to stress
MC63_RS00500	COG3691	Protein conserved in bacteria
MC63_RS00525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MC63_RS00540	COG3678	ATP-independent chaperone mediated protein folding
MC63_RS00545	COG0745	RESPONSE REGULATOR receiver
MC63_RS00550	COG2205	protein histidine kinase activity
MC63_RS00555	COG2258	MOSC domain
MC63_RS00565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MC63_RS00620	COG3383	formate dehydrogenase (NAD+) activity
MC63_RS00620	COG0243	molybdopterin cofactor binding
MC63_RS00625	COG3383	formate dehydrogenase (NAD+) activity
MC63_RS00625	COG0243	molybdopterin cofactor binding
MC63_RS00630	COG0437	4 iron, 4 sulfur cluster binding
MC63_RS00635	COG2864	formate dehydrogenase
MC63_RS00645	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MC63_RS00650	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MC63_RS00670	COG0456	acetyltransferase
MC63_RS00685	COG1011	Hydrolase
MC63_RS00690	COG1349	DNA-binding transcription factor activity
MC63_RS00695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MC63_RS00700	COG2084	Dehydrogenase
MC63_RS00710	COG2942	2-epimerase
MC63_RS00715	COG2017	converts alpha-aldose to the beta-anomer
MC63_RS00725	COG2211	Major facilitator Superfamily
MC63_RS00745	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MC63_RS00755	COG1082	Xylose isomerase domain protein TIM barrel
MC63_RS00760	COG2188	Transcriptional regulator
MC63_RS00765	COG1217	gtp-binding protein TYPA
MC63_RS00770	COG0174	glutamine synthetase
MC63_RS00780	COG3852	Histidine kinase
MC63_RS00785	COG2204	response regulator
MC63_RS00795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MC63_RS00810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MC63_RS00810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MC63_RS00820	COG0204	Acyl-transferase
MC63_RS00825	COG5339	Protein conserved in bacteria
MC63_RS00830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MC63_RS00840	COG3084	Protein conserved in bacteria
MC63_RS00845	COG0746	molybdenum cofactor guanylyltransferase activity
MC63_RS00850	COG1763	Mo-molybdopterin cofactor biosynthetic process
MC63_RS00880	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
MC63_RS00885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MC63_RS00890	COG1739	Uncharacterized protein family UPF0029
MC63_RS00910	COG0543	2 iron, 2 sulfur cluster binding
MC63_RS00920	COG0250	Participates in transcription elongation, termination and antitermination
MC63_RS00930	COG0805	protein transport
MC63_RS00935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MC63_RS00940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MC63_RS00950	COG3165	ubiquinone biosynthetic process from chorismate
MC63_RS00960	COG1322	Protein conserved in bacteria
MC63_RS00965	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MC63_RS00970	COG0412	Dienelactone hydrolase
MC63_RS00980	COG0583	DNA-binding transcription factor activity
MC63_RS00985	COG0697	spore germination
MC63_RS00990	COG0561	phosphatase activity
MC63_RS00995	COG2267	carboxylic ester hydrolase activity
MC63_RS01000	COG1280	lysine exporter protein (LysE YggA)
MC63_RS01020	COG0514	ATP-dependent DNA helicase (RecQ)
MC63_RS01025	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
MC63_RS01030	COG2050	protein possibly involved in aromatic compounds catabolism
MC63_RS01035	COG2962	Rard protein
MC63_RS01050	COG0598	Magnesium transport protein CorA
MC63_RS01055	COG3698	Phosphodiester glycosidase
MC63_RS01060	COG3385	transposase activity
MC63_RS01065	COG3698	Phosphodiester glycosidase
MC63_RS01070	COG0210	DNA helicase
MC63_RS01075	COG1011	Hydrolase
MC63_RS01085	COG3159	Protein conserved in bacteria
MC63_RS01095	COG5567	small periplasmic lipoprotein
MC63_RS01120	COG3072	Adenylate cyclase
MC63_RS01130	COG1587	Uroporphyrinogen-III synthase
MC63_RS01135	COG2959	enzyme of heme biosynthesis
MC63_RS01140	COG3071	HemY protein
MC63_RS01155	COG0641	radical SAM
MC63_RS01180	COG1113	amino acid transport
MC63_RS01200	COG2244	polysaccharide biosynthetic process
MC63_RS01205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MC63_RS01210	COG0456	acetyltransferase
MC63_RS01215	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MC63_RS01220	COG1088	dTDP-glucose 4,6-dehydratase activity
MC63_RS01225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MC63_RS01230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MC63_RS01235	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
MC63_RS01240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MC63_RS01245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MC63_RS01255	COG3118	belongs to the thioredoxin family
MC63_RS01270	COG0210	DNA helicase
MC63_RS01275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC63_RS01285	COG0583	DNA-binding transcription factor activity
MC63_RS01290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC63_RS01300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MC63_RS01305	COG3978	acetolactate synthase activity
MC63_RS01325	COG0606	chelatase, subunit chli
MC63_RS01330	COG3085	chromosome segregation
MC63_RS01370	COG2186	Transcriptional regulator
MC63_RS01375	COG0477	Major facilitator Superfamily
MC63_RS01380	COG1609	Transcriptional regulator
MC63_RS01385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MC63_RS01395	COG1172	Belongs to the binding-protein-dependent transport system permease family
MC63_RS01405	COG3385	transposase activity
MC63_RS01425	COG3385	transposase activity
MC63_RS01445	COG1522	sequence-specific DNA binding
MC63_RS01450	COG0716	FMN binding
MC63_RS01465	COG3312	ion transport
MC63_RS01530	COG3121	Chaperone
MC63_RS01555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MC63_RS01560	COG0573	inorganic phosphate transmembrane transporter activity
MC63_RS01565	COG0581	inorganic phosphate transmembrane transporter activity
MC63_RS01570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MC63_RS01575	COG0704	Plays a role in the regulation of phosphate uptake
MC63_RS01580	COG3711	transcriptional antiterminator
MC63_RS01585	COG2190	(PTS) system
MC63_RS01585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MC63_RS01585	COG1263	PTS System
MC63_RS01590	COG2723	6-phospho-beta-galactosidase activity
MC63_RS01600	COG2382	esterase
MC63_RS01605	COG0363	glucosamine-6-phosphate deaminase activity
MC63_RS01610	COG3196	Protein conserved in bacteria
MC63_RS01620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC63_RS01625	COG2252	PERMEase
MC63_RS01630	COG0431	NADPH-dependent FMN reductase
MC63_RS01635	COG2091	lysine biosynthetic process via aminoadipic acid
MC63_RS01650	COG3436	PFAM IS66 Orf2 family protein
MC63_RS01675	COG0814	amino acid
MC63_RS01725	COG0592	DNA-directed DNA polymerase activity
MC63_RS01735	COG0187	DNA topoisomerase II activity
MC63_RS01740	COG3753	Protein conserved in bacteria
MC63_RS01745	COG0561	phosphatase activity
MC63_RS01755	COG2186	Transcriptional regulator
MC63_RS01765	COG0800	Aldolase
MC63_RS01775	COG2271	Major facilitator Superfamily
MC63_RS01790	COG5645	(Lipo)protein
MC63_RS01810	COG2188	Transcriptional regulator
MC63_RS01825	COG2207	Transcriptional regulator
MC63_RS01835	COG3119	arylsulfatase activity
MC63_RS01845	COG2149	membrane
MC63_RS01855	COG0641	radical SAM
MC63_RS01860	COG2814	Major facilitator Superfamily
MC63_RS01875	COG0028	Belongs to the TPP enzyme family
MC63_RS01880	COG0440	acetolactate synthase activity
MC63_RS01885	COG2197	response regulator
MC63_RS01890	COG3851	Histidine kinase
MC63_RS01895	COG2271	Major facilitator Superfamily
MC63_RS01900	COG2271	Major facilitator Superfamily
MC63_RS01910	COG2252	PERMEase
MC63_RS01930	COG1464	Belongs to the NlpA lipoprotein family
MC63_RS01935	COG0697	spore germination
MC63_RS01970	COG3468	outer membrane autotransporter barrel domain protein
MC63_RS02075	COG1501	Belongs to the glycosyl hydrolase 31 family
MC63_RS02080	COG2982	Protein involved in outer membrane biogenesis
MC63_RS02085	COG2233	PERMEase
MC63_RS02090	COG0786	glutamate:sodium symporter activity
MC63_RS02095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MC63_RS02100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MC63_RS02105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MC63_RS02115	COG0194	GDP metabolic process
MC63_RS02125	COG2860	membrane
MC63_RS02130	COG3645	SOS response
MC63_RS02140	COG1561	YicC-like family, N-terminal region
MC63_RS02165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MC63_RS02195	COG1519	Transferase
MC63_RS02205	COG0859	PFAM glycosyl transferase family 9
MC63_RS02210	COG0438	transferase activity, transferring glycosyl groups
MC63_RS02215	COG0515	serine threonine protein kinase
MC63_RS02225	COG3642	lipopolysaccharide core region biosynthetic process
MC63_RS02245	COG0859	PFAM glycosyl transferase family 9
MC63_RS02250	COG0859	PFAM glycosyl transferase family 9
MC63_RS02265	COG0156	8-amino-7-oxononanoate synthase activity
MC63_RS02275	COG1216	Glycosyl transferase, family 2
MC63_RS02280	COG2861	carbohydrate metabolic process
MC63_RS02285	COG4942	peptidase
MC63_RS02300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MC63_RS02305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MC63_RS02320	COG1045	serine acetyltransferase
MC63_RS02325	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MC63_RS02335	COG2186	Transcriptional regulator
MC63_RS02340	COG1620	l-lactate permease
MC63_RS02345	COG5295	Hep Hag repeat protein
MC63_RS02370	COG3722	fumarate hydratase activity
MC63_RS02380	COG2213	PTS system mannitol-specific
MC63_RS02380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS02400	COG0625	glutathione transferase activity
MC63_RS02410	COG3276	selenocysteine insertion sequence binding
MC63_RS02415	COG1454	alcohol dehydrogenase
MC63_RS02420	COG1012	belongs to the aldehyde dehydrogenase family
MC63_RS02435	COG1566	PFAM secretion protein HlyD family protein
MC63_RS02440	COG1566	PFAM secretion protein HlyD family protein
MC63_RS02460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC63_RS02465	COG1129	ABC transporter
MC63_RS02465	COG0842	Transport permease protein
MC63_RS02470	COG0842	Transport permease protein
MC63_RS02500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC63_RS02505	COG0601	transmembrane transport
MC63_RS02510	COG0747	negative chemotaxis
MC63_RS02515	COG2091	lysine biosynthetic process via aminoadipic acid
MC63_RS02520	COG0628	permease
MC63_RS02535	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MC63_RS02550	COG3714	YhhN family
MC63_RS02560	COG3776	membrane
MC63_RS02565	COG0742	ribosomal rna small subunit methyltransferase
MC63_RS02570	COG0552	protein localization to endoplasmic reticulum
MC63_RS02575	COG2884	Cell division ATP-binding protein ftsE
MC63_RS02580	COG2177	Part of the ABC transporter FtsEX involved in
MC63_RS02585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MC63_RS02590	COG0683	leucine binding
MC63_RS02595	COG0456	acetyltransferase
MC63_RS02600	COG0683	leucine binding
MC63_RS02605	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC63_RS02610	COG4177	L-phenylalanine transmembrane transporter activity
MC63_RS02615	COG0411	ABC transporter
MC63_RS02620	COG0410	ABC transporter
MC63_RS02630	COG1175	transmembrane transport
MC63_RS02645	COG0584	glycerophosphoryl diester phosphodiesterase
MC63_RS02655	COG0405	Gamma-glutamyltransferase
MC63_RS02660	COG1247	-acetyltransferase
MC63_RS02665	COG0673	inositol 2-dehydrogenase activity
MC63_RS02670	COG1741	Belongs to the pirin family
MC63_RS02675	COG1609	Transcriptional regulator
MC63_RS02680	COG3265	gluconokinase activity
MC63_RS02685	COG2610	gluconate transmembrane transporter activity
MC63_RS02690	COG2095	MarC family integral membrane protein
MC63_RS02695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MC63_RS02720	COG0058	SHG alpha-glucan phosphorylase activity
MC63_RS02725	COG3385	transposase activity
MC63_RS02730	COG2197	response regulator
MC63_RS02735	COG0583	DNA-binding transcription factor activity
MC63_RS02740	COG1295	ribonuclease BN
MC63_RS02745	COG0477	Major facilitator Superfamily
MC63_RS02750	COG2982	Protein involved in outer membrane biogenesis
MC63_RS02755	COG2200	EAL domain
MC63_RS02765	COG0612	Peptidase, M16
MC63_RS02775	COG2200	EAL domain
MC63_RS02775	COG2199	diguanylate cyclase activity
MC63_RS02795	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MC63_RS02800	COG1215	transferase activity, transferring glycosyl groups
MC63_RS02910	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MC63_RS02930	COG2081	HI0933 family
MC63_RS02935	COG0306	phosphate transporter
MC63_RS02945	COG0589	response to stress
MC63_RS02965	COG0339	signal peptide processing
MC63_RS02970	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MC63_RS02975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC63_RS02985	COG0640	Transcriptional regulator
MC63_RS02990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MC63_RS02995	COG1393	Belongs to the ArsC family
MC63_RS03025	COG3065	identical protein binding
MC63_RS03050	COG3247	response to pH
MC63_RS03055	COG2771	luxR family
MC63_RS03080	COG1278	Cold shock
MC63_RS03085	COG2944	sequence-specific DNA binding
MC63_RS03100	COG2885	chlorophyll binding
MC63_RS03105	COG0243	molybdopterin cofactor binding
MC63_RS03110	COG0456	acetyltransferase
MC63_RS03115	COG2818	Glycosylase
MC63_RS03120	COG5571	outer membrane autotransporter
MC63_RS03125	COG2223	nitrite transmembrane transporter activity
MC63_RS03130	COG2194	sulfuric ester hydrolase activity
MC63_RS03140	COG0747	negative chemotaxis
MC63_RS03150	COG0601	transmembrane transport
MC63_RS03155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC63_RS03160	COG0444	Belongs to the ABC transporter superfamily
MC63_RS03165	COG4608	Belongs to the ABC transporter superfamily
MC63_RS03170	COG0814	amino acid
MC63_RS03215	COG2194	sulfuric ester hydrolase activity
MC63_RS03245	COG1414	Transcriptional regulator
MC63_RS03250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC63_RS03255	COG3977	Valine--pyruvate aminotransferase
MC63_RS03265	COG2992	FlgJ-related protein
MC63_RS03275	COG4214	carbohydrate transport
MC63_RS03285	COG4213	ABC transporter substrate-binding protein
MC63_RS03295	COG1070	Carbohydrate kinase
MC63_RS03300	COG4682	membrane
MC63_RS03305	COG4682	membrane
MC63_RS03310	COG3274	enterobacterial common antigen metabolic process
MC63_RS03340	COG2207	Transcriptional regulator
MC63_RS03355	COG1858	cytochrome C peroxidase
MC63_RS03370	COG3385	transposase activity
MC63_RS03380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MC63_RS03395	COG1349	DNA-binding transcription factor activity
MC63_RS03400	COG4650	regulator
MC63_RS03425	COG0058	SHG alpha-glucan phosphorylase activity
MC63_RS03430	COG1640	4-alpha-glucanotransferase
MC63_RS03435	COG2610	gluconate transmembrane transporter activity
MC63_RS03465	COG5464	transposase or invertase
MC63_RS03475	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MC63_RS03480	COG1918	ferrous iron import across plasma membrane
MC63_RS03485	COG2183	response to ionizing radiation
MC63_RS03490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MC63_RS03510	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MC63_RS03520	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MC63_RS03525	COG1011	Hydrolase
MC63_RS03535	COG0494	nUDIX hydrolase
MC63_RS03540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MC63_RS03545	COG4972	Pilus assembly protein
MC63_RS03550	COG3166	PFAM Fimbrial assembly family protein
MC63_RS03565	COG4796	Type ii and iii secretion system protein
MC63_RS03580	COG3266	domain, Protein
MC63_RS03585	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MC63_RS03590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MC63_RS03600	COG0180	Tryptophanyl-tRNA synthetase
MC63_RS03605	COG2188	Transcriptional regulator
MC63_RS03615	COG3457	Alanine racemase
MC63_RS03620	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MC63_RS03625	COG1735	metal-dependent hydrolase with the TIM-barrel fold
MC63_RS03640	COG0626	cystathionine gamma-synthase activity
MC63_RS03645	COG2188	Transcriptional regulator
MC63_RS03660	COG2222	sugar isomerase
MC63_RS03680	COG2116	formate transmembrane transporter activity
MC63_RS03685	COG2146	nitrite reductase [NAD(P)H] activity
MC63_RS03690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MC63_RS03705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MC63_RS03715	COG2184	nucleotidyltransferase activity
MC63_RS03720	COG0512	Glutamine amidotransferase of anthranilate synthase
MC63_RS03730	COG1289	transmembrane transporter activity
MC63_RS03735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MC63_RS03740	COG1765	OsmC-like protein
MC63_RS03745	COG3954	Phosphoribulokinase
MC63_RS03755	COG0429	hydrolase of the alpha beta-hydrolase fold
MC63_RS03760	COG0488	(ABC) transporter
MC63_RS03775	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MC63_RS03780	COG1047	Peptidyl-prolyl cis-trans
MC63_RS03790	COG0545	Peptidyl-prolyl cis-trans isomerase
MC63_RS03795	COG2964	Protein conserved in bacteria
MC63_RS03870	COG0089	rRNA binding
MC63_RS03960	COG0201	protein transport
MC63_RS04000	COG3436	PFAM IS66 Orf2 family protein
MC63_RS04015	COG0569	domain protein
MC63_RS04035	COG0758	DNA mediated transformation
MC63_RS04045	COG0551	DNA topoisomerase type I activity
MC63_RS04065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MC63_RS04105	COG1126	abc transporter atp-binding protein
MC63_RS04110	COG0765	amino acid transport
MC63_RS04120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC63_RS04135	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MC63_RS04155	COG4145	pantothenate transmembrane transporter activity
MC63_RS04160	COG3924	membrane
MC63_RS04165	COG0439	Biotin carboxylase
MC63_RS04170	COG0511	ligase activity, forming carbon-carbon bonds
MC63_RS04175	COG0604	alcohol dehydrogenase
MC63_RS04180	COG2200	EAL domain
MC63_RS04180	COG2199	diguanylate cyclase activity
MC63_RS04190	COG1077	Cell shape determining protein MreB Mrl
MC63_RS04195	COG1792	Involved in formation and maintenance of cell shape
MC63_RS04200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MC63_RS04210	COG1530	ribonuclease E activity
MC63_RS04215	COG3164	Protein of unknown function
MC63_RS04220	COG0312	modulator of DNA gyrase
MC63_RS04225	COG0583	DNA-binding transcription factor activity
MC63_RS04245	COG2732	(Barnase) inhibitor
MC63_RS04265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MC63_RS04270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MC63_RS04275	COG3105	Protein conserved in bacteria
MC63_RS04280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MC63_RS04295	COG0625	glutathione transferase activity
MC63_RS04300	COG2969	positive regulation of protein catabolic process
MC63_RS04305	COG3069	C4-dicarboxylate transmembrane transporter activity
MC63_RS04340	COG2731	YhcH YjgK YiaL family protein
MC63_RS04355	COG4804	nuclease activity
MC63_RS04360	COG0493	'glutamate synthase
MC63_RS04365	COG0069	glutamate synthase activity
MC63_RS04365	COG0070	glutamate synthase
MC63_RS04365	COG0067	glutamate synthase
MC63_RS04370	COG1242	4 iron, 4 sulfur cluster binding
MC63_RS04375	COG2198	Histidine kinase
MC63_RS04375	COG5002	protein histidine kinase activity
MC63_RS04375	COG0784	Response regulator, receiver
MC63_RS04380	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MC63_RS04390	COG0515	serine threonine protein kinase
MC63_RS04395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS04410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MC63_RS04415	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MC63_RS04420	COG1137	ATPase activity
MC63_RS04425	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MC63_RS04430	COG3117	lipopolysaccharide transmembrane transporter activity
MC63_RS04435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MC63_RS04445	COG0530	calcium, potassium:sodium antiporter activity
MC63_RS04450	COG1127	ABC transporter
MC63_RS04455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MC63_RS04460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MC63_RS04465	COG2854	intermembrane phospholipid transfer
MC63_RS04470	COG3113	response to antibiotic
MC63_RS04475	COG5007	Belongs to the BolA IbaG family
MC63_RS04485	COG3423	Transcriptional regulator
MC63_RS04490	COG0142	geranyltranstransferase activity
MC63_RS04505	COG0697	spore germination
MC63_RS04515	COG2027	D-alanyl-D-alanine carboxypeptidase
MC63_RS04520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MC63_RS04525	COG1534	Rna-binding protein
MC63_RS04535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MC63_RS04540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MC63_RS04550	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MC63_RS04580	COG0195	Participates in both transcription termination and antitermination
MC63_RS04620	COG0513	Belongs to the DEAD box helicase family
MC63_RS04625	COG0814	amino acid
MC63_RS04630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MC63_RS04635	COG0826	peptidase U32
MC63_RS04640	COG0826	peptidase U32
MC63_RS04645	COG3154	lipid carrier protein
MC63_RS04650	COG3153	acetyltransferase
MC63_RS04665	COG0693	protein deglycase activity
MC63_RS04670	COG0702	epimerase
MC63_RS04675	COG0701	Predicted permease
MC63_RS04680	COG2823	Periplasmic or secreted lipoprotein
MC63_RS04700	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MC63_RS04705	COG3539	Fimbrial protein
MC63_RS04720	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS04725	COG3716	PTS system mannose fructose sorbose family IID component
MC63_RS04735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MC63_RS04745	COG1349	DNA-binding transcription factor activity
MC63_RS04750	COG2721	sulfolactate sulfo-lyase activity
MC63_RS04755	COG2271	Major facilitator Superfamily
MC63_RS04765	COG2084	Dehydrogenase
MC63_RS04770	COG1929	Belongs to the glycerate kinase type-1 family
MC63_RS04800	COG0583	DNA-binding transcription factor activity
MC63_RS04805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC63_RS04815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MC63_RS04825	COG0251	oxidation-reduction process
MC63_RS04830	COG1760	l-serine dehydratase
MC63_RS04835	COG0814	amino acid
MC63_RS04850	COG1741	Belongs to the pirin family
MC63_RS04855	COG0583	DNA-binding transcription factor activity
MC63_RS04860	COG3152	Membrane
MC63_RS04865	COG0435	Glutathione S-transferase
MC63_RS04870	COG2259	Doxx family
MC63_RS04880	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
MC63_RS04885	COG4575	ribosome binding
MC63_RS04900	COG0586	Pfam SNARE associated Golgi protein
MC63_RS04905	COG2186	Transcriptional regulator
MC63_RS04940	COG2271	Major facilitator Superfamily
MC63_RS04950	COG2721	sulfolactate sulfo-lyase activity
MC63_RS04960	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MC63_RS04965	COG0861	Integral membrane protein TerC family
MC63_RS04970	COG0673	inositol 2-dehydrogenase activity
MC63_RS04975	COG2949	membrane
MC63_RS04980	COG1451	nucleotide metabolic process
MC63_RS04990	COG4680	protein conserved in bacteria
MC63_RS04995	COG5499	transcription regulator containing HTH domain
MC63_RS05000	COG0446	pyridine nucleotide-disulphide oxidoreductase
MC63_RS05000	COG1902	pentaerythritol trinitrate reductase activity
MC63_RS05005	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
MC63_RS05005	COG3408	Glycogen debranching enzyme
MC63_RS05015	COG0531	amino acid
MC63_RS05020	COG2731	YhcH YjgK YiaL family protein
MC63_RS05025	COG3250	beta-galactosidase activity
MC63_RS05030	COG1609	Transcriptional regulator
MC63_RS05045	COG0840	transmembrane signaling receptor activity
MC63_RS05050	COG1695	Transcriptional regulator
MC63_RS05070	COG3385	transposase activity
MC63_RS05075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MC63_RS05080	COG0358	DNA primase activity
MC63_RS05085	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MC63_RS05095	COG0471	metal ion transport
MC63_RS05100	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MC63_RS05120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MC63_RS05135	COG4991	sh3 domain protein
MC63_RS05140	COG3025	triphosphatase activity
MC63_RS05185	COG3385	transposase activity
MC63_RS05190	COG3539	Fimbrial protein
MC63_RS05195	COG3121	Chaperone
MC63_RS05205	COG3539	Fimbrial protein
MC63_RS05215	COG2960	long-chain fatty acid transporting porin activity
MC63_RS05230	COG3384	dioxygenase
MC63_RS05235	COG0754	glutathionylspermidine amidase activity
MC63_RS05245	COG1538	Outer membrane efflux protein
MC63_RS05250	COG0494	nUDIX hydrolase
MC63_RS05255	COG3151	Protein conserved in bacteria
MC63_RS05260	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MC63_RS05265	COG3150	esterase
MC63_RS05270	COG0187	DNA topoisomerase II activity
MC63_RS05275	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MC63_RS05280	COG2249	NAD(P)H dehydrogenase (quinone) activity
MC63_RS05290	COG0642	Histidine kinase
MC63_RS05295	COG0745	RESPONSE REGULATOR receiver
MC63_RS05300	COG3111	PFAM Bacterial OB fold (BOF) protein
MC63_RS05305	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MC63_RS05310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MC63_RS05315	COG0204	Acyl-transferase
MC63_RS05320	COG2132	Multicopper oxidase
MC63_RS05325	COG1032	radical SAM domain protein
MC63_RS05330	COG4238	major outer membrane lipoprotein
MC63_RS05340	COG0656	L-ascorbic acid biosynthetic process
MC63_RS05345	COG1979	alcohol dehydrogenase
MC63_RS05360	COG2207	Transcriptional regulator
MC63_RS05365	COG0586	Pfam SNARE associated Golgi protein
MC63_RS05370	COG0626	cystathionine gamma-synthase activity
MC63_RS05375	COG0811	peptide transport
MC63_RS05380	COG0848	biopolymer transport protein
MC63_RS05385	COG1028	Short-chain dehydrogenase reductase Sdr
MC63_RS05395	COG0667	Aldo Keto reductase
MC63_RS05410	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
MC63_RS05415	COG0437	4 iron, 4 sulfur cluster binding
MC63_RS05420	COG5557	Pfam Polysulphide reductase, NrfD
MC63_RS05425	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
MC63_RS05430	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MC63_RS05435	COG1773	rubredoxin
MC63_RS05445	COG0298	carbon dioxide binding
MC63_RS05450	COG0625	glutathione transferase activity
MC63_RS05455	COG0754	glutathionylspermidine amidase activity
MC63_RS05460	COG0306	phosphate transporter
MC63_RS05465	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MC63_RS05470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MC63_RS05475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MC63_RS05480	COG2244	polysaccharide biosynthetic process
MC63_RS05490	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
MC63_RS05495	COG0795	lipopolysaccharide-transporting ATPase activity
MC63_RS05505	COG0156	8-amino-7-oxononanoate synthase activity
MC63_RS05510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MC63_RS05535	COG0277	FAD linked oxidase domain protein
MC63_RS05540	COG0277	FAD linked oxidase domain protein
MC63_RS05545	COG0247	lactate metabolic process
MC63_RS05550	COG3193	protein, possibly involved in utilization of glycolate and propanediol
MC63_RS05560	COG1620	l-lactate permease
MC63_RS05600	COG1811	Na channel or pump
MC63_RS05610	COG2211	Major facilitator Superfamily
MC63_RS05625	COG1194	a g-specific adenine glycosylase
MC63_RS05635	COG3171	Protein conserved in bacteria
MC63_RS05645	COG0252	asparaginase activity
MC63_RS05670	COG0330	HflC and HflK could
MC63_RS05675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MC63_RS05680	COG0501	Belongs to the peptidase M48B family
MC63_RS05700	COG1166	arginine decarboxylase activity
MC63_RS05725	COG2814	Major facilitator Superfamily
MC63_RS05735	COG2356	endonuclease I
MC63_RS05740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MC63_RS05745	COG0189	ligase activity
MC63_RS05760	COG2805	Type II/IV secretion system protein
MC63_RS05765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MC63_RS05770	COG0762	integral membrane protein
MC63_RS05785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MC63_RS05795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MC63_RS05805	COG1063	alcohol dehydrogenase
MC63_RS05810	COG1494	fructose-1,6-bisphosphatase
MC63_RS05820	COG1072	(Pantothenic acid kinase))
MC63_RS05825	COG1122	ATPase activity
MC63_RS05830	COG1122	ATPase activity
MC63_RS05865	COG0191	fructose-bisphosphate aldolase activity
MC63_RS05870	COG0668	transmembrane transport
MC63_RS05880	COG2968	Membrane
MC63_RS05885	COG0583	DNA-binding transcription factor activity
MC63_RS05895	COG0427	acetyl-CoA hydrolase
MC63_RS05900	COG1024	Enoyl-CoA hydratase
MC63_RS05905	COG1703	isobutyryl-CoA mutase activity
MC63_RS05910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MC63_RS05910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MC63_RS05925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC63_RS05940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MC63_RS05960	COG0006	proline dipeptidase activity
MC63_RS05965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC63_RS05970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC63_RS05995	COG1028	Short-chain dehydrogenase reductase Sdr
MC63_RS06000	COG2723	6-phospho-beta-galactosidase activity
MC63_RS06010	COG1272	protein, Hemolysin III
MC63_RS06030	COG0716	FMN binding
MC63_RS06035	COG4974	Belongs to the 'phage' integrase family
MC63_RS06040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MC63_RS06045	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MC63_RS06075	COG2233	PERMEase
MC63_RS06090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MC63_RS06100	COG4942	peptidase
MC63_RS06110	COG4974	Belongs to the 'phage' integrase family
MC63_RS06145	COG2771	luxR family
MC63_RS06155	COG0814	amino acid
MC63_RS06160	COG0814	amino acid
MC63_RS06165	COG0183	Belongs to the thiolase family
MC63_RS06175	COG1028	Short-chain dehydrogenase reductase Sdr
MC63_RS06185	COG1794	racemase activity, acting on amino acids and derivatives
MC63_RS06190	COG0583	DNA-binding transcription factor activity
MC63_RS06200	COG1609	Transcriptional regulator
MC63_RS06215	COG0667	Aldo Keto reductase
MC63_RS06225	COG0861	Integral membrane protein TerC family
MC63_RS06245	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
MC63_RS06265	COG4795	General secretion pathway protein
MC63_RS06275	COG4967	type IV pilus modification protein PilV
MC63_RS06280	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MC63_RS06290	COG1074	ATP-dependent DNA helicase activity
MC63_RS06295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MC63_RS06305	COG0860	N-Acetylmuramoyl-L-alanine amidase
MC63_RS06320	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MC63_RS06325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MC63_RS06330	COG2166	iron-sulfur cluster assembly
MC63_RS06335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MC63_RS06345	COG0583	DNA-binding transcription factor activity
MC63_RS06350	COG2363	Small membrane protein
MC63_RS06360	COG1349	DNA-binding transcription factor activity
MC63_RS06380	COG0738	Major facilitator superfamily
MC63_RS06385	COG0235	Class ii aldolase
MC63_RS06390	COG1454	alcohol dehydrogenase
MC63_RS06400	COG1760	l-serine dehydratase
MC63_RS06405	COG0814	amino acid
MC63_RS06410	COG3385	transposase activity
MC63_RS06415	COG1611	Belongs to the LOG family
MC63_RS06430	COG3098	single-species biofilm formation
MC63_RS06435	COG0564	pseudouridine synthase activity
MC63_RS06440	COG0716	FMN binding
MC63_RS06445	COG2271	Major facilitator Superfamily
MC63_RS06450	COG4948	Mandelate Racemase Muconate Lactonizing
MC63_RS06455	COG4948	Mandelate Racemase Muconate Lactonizing
MC63_RS06470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MC63_RS06475	COG3956	TIGRFAM MazG family protein
MC63_RS06490	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MC63_RS06500	COG0602	queuosine metabolic process
MC63_RS06510	COG1070	Carbohydrate kinase
MC63_RS06515	COG2223	nitrite transmembrane transporter activity
MC63_RS06530	COG0477	Major facilitator Superfamily
MC63_RS06535	COG2086	electron transfer activity
MC63_RS06540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MC63_RS06545	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MC63_RS06550	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MC63_RS06555	COG0644	oxidoreductase
MC63_RS06560	COG0720	synthase
MC63_RS06595	COG2234	aminopeptidase activity
MC63_RS06650	COG4942	peptidase
MC63_RS06650	COG1388	LysM domain
MC63_RS06655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MC63_RS06680	COG3423	Transcriptional regulator
MC63_RS06695	COG2842	Transposition protein
MC63_RS06710	COG0235	Class ii aldolase
MC63_RS06720	COG2084	Dehydrogenase
MC63_RS06725	COG1349	DNA-binding transcription factor activity
MC63_RS06750	COG3604	Transcriptional regulator
MC63_RS06755	COG0309	Hydrogenase expression formation protein (HypE)
MC63_RS06760	COG0409	Hydrogenase expression formation protein
MC63_RS06765	COG0298	carbon dioxide binding
MC63_RS06770	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MC63_RS06775	COG0375	protein maturation
MC63_RS06790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC63_RS06795	COG0651	ATP synthesis coupled electron transport
MC63_RS06800	COG0650	Formate hydrogenlyase subunit 4
MC63_RS06805	COG3261	NADH dehydrogenase
MC63_RS06805	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MC63_RS06810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC63_RS06815	COG3260	NADH ubiquinone oxidoreductase 20
MC63_RS06825	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MC63_RS06835	COG4680	protein conserved in bacteria
MC63_RS06840	COG5499	transcription regulator containing HTH domain
MC63_RS06845	COG2723	6-phospho-beta-galactosidase activity
MC63_RS06850	COG1263	PTS System
MC63_RS06850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MC63_RS06855	COG1609	Transcriptional regulator
MC63_RS06860	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC63_RS06865	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MC63_RS06890	COG1349	DNA-binding transcription factor activity
MC63_RS06895	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS06900	COG1028	Short-chain dehydrogenase reductase Sdr
MC63_RS06910	COG3732	PTS system glucitol sorbitol-specific
MC63_RS06915	COG3730	PTS system glucitol sorbitol-specific
MC63_RS06920	COG2951	lytic endotransglycosylase activity
MC63_RS06925	COG1546	Belongs to the CinA family
MC63_RS06945	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MC63_RS06970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC63_RS06975	COG1238	metal cluster binding
MC63_RS06990	COG2814	Major facilitator Superfamily
MC63_RS07000	COG1846	Transcriptional regulator
MC63_RS07010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MC63_RS07020	COG2113	Glycine betaine
MC63_RS07025	COG4176	ABC-type proline glycine betaine transport system permease component
MC63_RS07030	COG4175	Glycine betaine
MC63_RS07035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MC63_RS07040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MC63_RS07050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MC63_RS07055	COG4575	ribosome binding
MC63_RS07075	COG2916	Histone family protein nucleoid-structuring protein H-NS
MC63_RS07080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MC63_RS07085	COG0640	Transcriptional regulator
MC63_RS07090	COG0401	homolog of Blt101
MC63_RS07095	COG1652	LysM domain
MC63_RS07115	COG0582	viral genome integration into host DNA
MC63_RS07130	COG2867	negative regulation of translational initiation
MC63_RS07140	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC63_RS07145	COG0497	DNA recombination
MC63_RS07165	COG4536	flavin adenine dinucleotide binding
MC63_RS07170	COG4137	Cytochrome C assembly protein
MC63_RS07175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MC63_RS07200	COG2885	chlorophyll binding
MC63_RS07220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MC63_RS07225	COG1605	Chorismate mutase
MC63_RS07225	COG0287	Prephenate dehydrogenase
MC63_RS07230	COG0077	Prephenate dehydratase
MC63_RS07230	COG1605	Chorismate mutase
MC63_RS07240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MC63_RS07250	COG0542	response to heat
MC63_RS07260	COG0564	pseudouridine synthase activity
MC63_RS07265	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC63_RS07295	COG0477	Major facilitator Superfamily
MC63_RS07300	COG5544	Lipoprotein
MC63_RS07305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC63_RS07310	COG1042	CoA-binding domain protein
MC63_RS07310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MC63_RS07310	COG0045	succinate-CoA ligase (ADP-forming) activity
MC63_RS07315	COG3148	PFAM DTW domain containing protein
MC63_RS07320	COG3118	belongs to the thioredoxin family
MC63_RS07325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MC63_RS07345	COG0583	DNA-binding transcription factor activity
MC63_RS07350	COG0513	Belongs to the DEAD box helicase family
MC63_RS07360	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MC63_RS07370	COG1595	DNA-templated transcription, initiation
MC63_RS07375	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
MC63_RS07380	COG3026	antisigma factor binding
MC63_RS07385	COG3086	response to oxidative stress
MC63_RS07395	COG0681	Belongs to the peptidase S26 family
MC63_RS07430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC63_RS07465	COG3436	PFAM IS66 Orf2 family protein
MC63_RS07540	COG1737	Transcriptional regulator
MC63_RS07545	COG0560	Phosphoserine phosphatase
MC63_RS07565	COG2205	protein histidine kinase activity
MC63_RS07570	COG3170	Tfp pilus assembly protein FimV
MC63_RS07575	COG2204	response regulator
MC63_RS07580	COG0347	Belongs to the P(II) protein family
MC63_RS07595	COG1940	carbohydrate kinase activity
MC63_RS07600	COG0457	Tetratricopeptide repeat
MC63_RS07610	COG1879	ABC-type sugar transport system periplasmic component
MC63_RS07615	COG1129	ABC transporter
MC63_RS07620	COG1172	Belongs to the binding-protein-dependent transport system permease family
MC63_RS07625	COG1063	alcohol dehydrogenase
MC63_RS07630	COG2017	converts alpha-aldose to the beta-anomer
MC63_RS07635	COG2259	Doxx family
MC63_RS07665	COG0583	DNA-binding transcription factor activity
MC63_RS07670	COG2814	Major facilitator Superfamily
MC63_RS07675	COG3711	transcriptional antiterminator
MC63_RS07680	COG1073	alpha beta
MC63_RS07685	COG0483	inositol monophosphate 1-phosphatase activity
MC63_RS07705	COG0822	iron-sulfur transferase activity
MC63_RS07725	COG0633	Ferredoxin
MC63_RS07730	COG2975	iron-sulfur cluster assembly
MC63_RS07785	COG2976	Protein conserved in bacteria
MC63_RS07800	COG1645	bacterial-type flagellum-dependent swarming motility
MC63_RS07810	COG0516	GMP reductase activity
MC63_RS07810	COG0517	IMP dehydrogenase activity
MC63_RS07830	COG3133	Outer membrane lipoprotein
MC63_RS07855	COG2200	EAL domain
MC63_RS07860	COG0248	Ppx GppA phosphatase
MC63_RS07865	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MC63_RS07870	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MC63_RS07885	COG2233	PERMEase
MC63_RS07895	COG1393	Belongs to the ArsC family
MC63_RS07900	COG4783	chaperone-mediated protein folding
MC63_RS07905	COG0628	permease
MC63_RS07925	COG3260	NADH ubiquinone oxidoreductase 20
MC63_RS07930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC63_RS07940	COG0651	ATP synthesis coupled electron transport
MC63_RS07950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MC63_RS07955	COG0650	Formate hydrogenlyase subunit 4
MC63_RS07965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC63_RS07970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MC63_RS07975	COG2716	regulation of RNA biosynthetic process
MC63_RS07985	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MC63_RS07995	COG2321	neutral zinc metallopeptidase
MC63_RS08005	COG0400	carboxylic ester hydrolase activity
MC63_RS08020	COG1393	Belongs to the ArsC family
MC63_RS08035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC63_RS08045	COG0493	'glutamate synthase
MC63_RS08045	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC63_RS08055	COG5342	invasion associated locus B
MC63_RS08060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MC63_RS08065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MC63_RS08070	COG0281	malic enzyme
MC63_RS08070	COG0280	phosphate acetyltransferase
MC63_RS08075	COG4810	utilization protein
MC63_RS08080	COG4917	ethanolamine utilization protein
MC63_RS08085	COG4819	ethanolamine utilization protein
MC63_RS08095	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MC63_RS08100	COG0531	amino acid
MC63_RS08105	COG0076	glutamate decarboxylase activity
MC63_RS08110	COG0076	glutamate decarboxylase activity
MC63_RS08150	COG0582	viral genome integration into host DNA
MC63_RS08155	COG4303	Ethanolamine ammonia lyase large subunit
MC63_RS08165	COG4816	utilization protein
MC63_RS08170	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MC63_RS08185	COG0860	N-Acetylmuramoyl-L-alanine amidase
MC63_RS08205	COG2837	iron assimilation
MC63_RS08210	COG1263	PTS System
MC63_RS08210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MC63_RS08225	COG1028	Short-chain dehydrogenase reductase Sdr
MC63_RS08230	COG4150	thiosulfate binding
MC63_RS08235	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MC63_RS08240	COG4208	sulfate ABC transporter
MC63_RS08250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MC63_RS08270	COG2190	(PTS) system
MC63_RS08275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MC63_RS08280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS08285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MC63_RS08295	COG3115	cell septum assembly
MC63_RS08305	COG3530	Putative quorum-sensing-regulated virulence factor
MC63_RS08310	COG0385	Bile acid
MC63_RS08315	COG0583	DNA-binding transcription factor activity
MC63_RS08350	COG3415	Transposase
MC63_RS08355	COG3415	Transposase
MC63_RS08375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MC63_RS08400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MC63_RS08405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MC63_RS08415	COG1363	Peptidase, m42
MC63_RS08425	COG2207	Transcriptional regulator
MC63_RS08430	COG3279	Response regulator of the LytR AlgR family
MC63_RS08435	COG3275	phosphorelay sensor kinase activity
MC63_RS08440	COG0436	Aminotransferase
MC63_RS08450	COG1560	Kdo2-lipid A biosynthetic process
MC63_RS08475	COG0028	Belongs to the TPP enzyme family
MC63_RS08480	COG0679	Auxin Efflux Carrier
MC63_RS08485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC63_RS08490	COG2205	protein histidine kinase activity
MC63_RS08490	COG0784	Response regulator, receiver
MC63_RS08490	COG2198	Histidine kinase
MC63_RS08490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC63_RS08495	COG2197	response regulator
MC63_RS08500	COG1566	PFAM secretion protein HlyD family protein
MC63_RS08505	COG0477	Major facilitator Superfamily
MC63_RS08530	COG3385	transposase activity
MC63_RS08550	COG0582	viral genome integration into host DNA
MC63_RS08560	COG2116	formate transmembrane transporter activity
MC63_RS08570	COG2853	Lipoprotein
MC63_RS08590	COG3691	Protein conserved in bacteria
MC63_RS08605	COG2062	phosphohistidine phosphatase, SixA
MC63_RS08610	COG3539	Fimbrial protein
MC63_RS08625	COG3539	Fimbrial protein
MC63_RS08635	COG3539	Fimbrial protein
MC63_RS08640	COG3539	Fimbrial protein
MC63_RS08670	COG0730	response to heat
MC63_RS08675	COG3101	peptidyl-lysine hydroxylation
MC63_RS08690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MC63_RS08710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MC63_RS08720	COG0586	Pfam SNARE associated Golgi protein
MC63_RS08730	COG0285	dihydrofolate synthase activity
MC63_RS08735	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
MC63_RS08740	COG1286	toxin biosynthetic process
MC63_RS08745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MC63_RS08750	COG0163	prenyltransferase activity
MC63_RS08755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC63_RS08760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC63_RS08765	COG4215	(ABC) transporter
MC63_RS08770	COG4160	amino acid transport
MC63_RS08775	COG4598	ABC transporter
MC63_RS08780	COG5464	transposase or invertase
MC63_RS08785	COG1090	epimerase
MC63_RS08790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MC63_RS08795	COG0625	glutathione transferase activity
MC63_RS08800	COG0625	glutathione transferase activity
MC63_RS08805	COG0622	Phosphoesterase
MC63_RS08810	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MC63_RS08815	COG1288	antiporter activity
MC63_RS08820	COG0857	belongs to the CobB CobQ family
MC63_RS08820	COG0280	phosphate acetyltransferase
MC63_RS08825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MC63_RS08840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC63_RS08845	COG0490	domain, Protein
MC63_RS08845	COG0471	metal ion transport
MC63_RS08855	COG0436	Aminotransferase
MC63_RS08860	COG0583	DNA-binding transcription factor activity
MC63_RS08880	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MC63_RS08885	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MC63_RS08905	COG0839	Belongs to the complex I subunit 6 family
MC63_RS08915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MC63_RS08920	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC63_RS08960	COG2153	protein acetylation
MC63_RS08965	COG4575	ribosome binding
MC63_RS08970	COG1169	isochorismate synthase
MC63_RS08985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MC63_RS08995	COG0318	PFAM AMP-dependent synthetase and ligase
MC63_RS09070	COG5464	transposase or invertase
MC63_RS09075	COG0247	lactate metabolic process
MC63_RS09085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MC63_RS09090	COG2271	Major facilitator Superfamily
MC63_RS09095	COG0584	glycerophosphoryl diester phosphodiesterase
MC63_RS09105	COG3642	lipopolysaccharide core region biosynthetic process
MC63_RS09110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC63_RS09115	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MC63_RS09120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MC63_RS09140	COG3468	outer membrane autotransporter barrel domain protein
MC63_RS09145	COG3468	outer membrane autotransporter barrel domain protein
MC63_RS09155	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MC63_RS09160	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
MC63_RS09165	COG3234	Protein of unknown function (DUF1175)
MC63_RS09185	COG2373	Large extracellular alpha-helical protein
MC63_RS09190	COG5445	Predicted secreted protein (DUF2300)
MC63_RS09195	COG4676	Protein conserved in bacteria
MC63_RS09200	COG2205	protein histidine kinase activity
MC63_RS09200	COG0784	Response regulator, receiver
MC63_RS09205	COG2197	response regulator
MC63_RS09210	COG0642	Histidine kinase
MC63_RS09210	COG2198	Histidine kinase
MC63_RS09220	COG1477	protein flavinylation
MC63_RS09225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MC63_RS09225	COG2169	Transcriptional regulator
MC63_RS09235	COG4615	Cyclic peptide transporter
MC63_RS09255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC63_RS09255	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC63_RS09260	COG3062	negative regulation of establishment of protein localization
MC63_RS09270	COG0437	4 iron, 4 sulfur cluster binding
MC63_RS09275	COG0348	domain, Protein
MC63_RS09280	COG3043	anaerobic respiration
MC63_RS09285	COG3005	denitrification pathway
MC63_RS09290	COG4133	protoheme IX ABC transporter activity
MC63_RS09295	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MC63_RS09300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MC63_RS09305	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MC63_RS09315	COG1138	Cytochrome C-type biogenesis protein
MC63_RS09320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC63_RS09325	COG3088	subunit of a heme lyase
MC63_RS09325	COG4235	cytochrome complex assembly
MC63_RS09330	COG2197	response regulator
MC63_RS09335	COG3468	outer membrane autotransporter barrel domain protein
MC63_RS09345	COG3083	sulfuric ester hydrolase activity
MC63_RS09365	COG1061	Type III restriction enzyme res subunit
MC63_RS09370	COG1187	pseudouridine synthase activity
MC63_RS09375	COG2814	Major facilitator Superfamily
MC63_RS09385	COG4172	Belongs to the ABC transporter superfamily
MC63_RS09390	COG4239	(ABC) transporter, permease
MC63_RS09395	COG4174	ABC transporter (Permease)
MC63_RS09400	COG4166	transmembrane transport
MC63_RS09405	COG2200	EAL domain
MC63_RS09410	COG0791	NLP P60 protein
MC63_RS09415	COG0671	phosphoesterase, PA-phosphatase related
MC63_RS09420	COG0523	cobalamin synthesis protein
MC63_RS09425	COG0246	Mannitol dehydrogenase
MC63_RS09445	COG2814	Major facilitator Superfamily
MC63_RS09450	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS09450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS09455	COG1105	Belongs to the carbohydrate kinase PfkB family
MC63_RS09460	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
MC63_RS09460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MC63_RS09460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MC63_RS09465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MC63_RS09470	COG2313	pseudouridylate synthase activity
MC63_RS09475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MC63_RS09480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MC63_RS09490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MC63_RS09495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MC63_RS09495	COG1522	sequence-specific DNA binding
MC63_RS09505	COG2855	membrane
MC63_RS09510	COG0583	DNA-binding transcription factor activity
MC63_RS09515	COG0833	amino acid
MC63_RS09525	COG4771	TonB-dependent receptor
MC63_RS09540	COG2311	Membrane
MC63_RS09545	COG1609	Transcriptional regulator
MC63_RS09550	COG1879	ABC-type sugar transport system periplasmic component
MC63_RS09555	COG1129	ABC transporter
MC63_RS09560	COG4211	Belongs to the binding-protein-dependent transport system permease family
MC63_RS09565	COG0167	dihydroorotate dehydrogenase activity
MC63_RS09565	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MC63_RS09580	COG2949	membrane
MC63_RS09590	COG1346	cytolysis
MC63_RS09600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MC63_RS09625	COG0586	Pfam SNARE associated Golgi protein
MC63_RS09635	COG1686	Belongs to the peptidase S11 family
MC63_RS09640	COG0277	FAD linked oxidase domain protein
MC63_RS09645	COG1472	Belongs to the glycosyl hydrolase 3 family
MC63_RS09650	COG1732	Glycine betaine
MC63_RS09665	COG1174	glycine betaine transport
MC63_RS09685	COG0789	Transcriptional regulator
MC63_RS09690	COG0582	viral genome integration into host DNA
MC63_RS09735	COG0500	methyltransferase
MC63_RS09755	COG3385	transposase activity
MC63_RS09760	COG3275	phosphorelay sensor kinase activity
MC63_RS09770	COG4807	Protein conserved in bacteria
MC63_RS09775	COG4808	Protein conserved in bacteria
MC63_RS09780	COG4715	Zinc finger, swim domain protein
MC63_RS09785	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MC63_RS09820	COG3831	ATPase activity
MC63_RS09850	COG0489	protein tyrosine kinase activity
MC63_RS09860	COG3539	Fimbrial protein
MC63_RS09865	COG3121	Chaperone
MC63_RS09870	COG3188	usher protein
MC63_RS09880	COG5455	response to cobalt ion
MC63_RS09900	COG0351	phosphomethylpyrimidine kinase
MC63_RS09905	COG3757	hydrolase, family 25
MC63_RS09910	COG2188	Transcriptional regulator
MC63_RS09915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MC63_RS09925	COG2211	Major facilitator Superfamily
MC63_RS09930	COG1830	Aldolase
MC63_RS09945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS09950	COG3414	Phosphotransferase system galactitol-specific IIB component
MC63_RS09960	COG1063	alcohol dehydrogenase
MC63_RS09985	COG0826	peptidase U32
MC63_RS09995	COG0745	RESPONSE REGULATOR receiver
MC63_RS10000	COG2205	protein histidine kinase activity
MC63_RS10025	COG3547	Transposase (IS116 IS110 IS902 family)
MC63_RS10030	COG4245	von Willebrand factor, type A
MC63_RS10040	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
MC63_RS10045	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
MC63_RS10050	COG0443	Heat shock 70 kDa protein
MC63_RS10055	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MC63_RS10065	COG3547	Transposase (IS116 IS110 IS902 family)
MC63_RS10085	COG2982	Protein involved in outer membrane biogenesis
MC63_RS10090	COG1253	flavin adenine dinucleotide binding
MC63_RS10095	COG1596	polysaccharide export
MC63_RS10100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MC63_RS10105	COG3206	protein involved in exopolysaccharide biosynthesis
MC63_RS10105	COG0489	protein tyrosine kinase activity
MC63_RS10115	COG1045	serine acetyltransferase
MC63_RS10120	COG0438	transferase activity, transferring glycosyl groups
MC63_RS10140	COG0110	maltose O-acetyltransferase activity
MC63_RS10145	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MC63_RS10150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC63_RS10155	COG1051	belongs to the nudix hydrolase family
MC63_RS10165	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MC63_RS10165	COG0662	Cupin 2, conserved barrel domain protein
MC63_RS10170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MC63_RS10175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MC63_RS10180	COG2244	polysaccharide biosynthetic process
MC63_RS10185	COG2327	Polysaccharide pyruvyl transferase
MC63_RS10190	COG0438	transferase activity, transferring glycosyl groups
MC63_RS10200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MC63_RS10275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MC63_RS10345	COG4115	mRNA cleavage
MC63_RS10350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC63_RS10355	COG0583	DNA-binding transcription factor activity
MC63_RS10365	COG0531	amino acid
MC63_RS10375	COG2391	methyltransferase activity
MC63_RS10380	COG0425	Belongs to the sulfur carrier protein TusA family
MC63_RS10385	COG2925	Exonuclease
MC63_RS10405	COG3436	PFAM IS66 Orf2 family protein
MC63_RS10410	COG4372	Transposase
MC63_RS10430	COG4372	Transposase
MC63_RS10435	COG3436	PFAM IS66 Orf2 family protein
MC63_RS10445	COG1289	transmembrane transporter activity
MC63_RS10515	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
MC63_RS10530	COG1376	ErfK ybiS ycfS ynhG family protein
MC63_RS10540	COG0583	DNA-binding transcription factor activity
MC63_RS10545	COG0583	DNA-binding transcription factor activity
MC63_RS10585	COG0477	Major facilitator Superfamily
MC63_RS10595	COG0582	viral genome integration into host DNA
MC63_RS10675	COG1403	HNH endonuclease
MC63_RS10680	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MC63_RS10725	COG3436	PFAM IS66 Orf2 family protein
MC63_RS10775	COG4695	Portal protein
MC63_RS10810	COG4386	tail sheath protein
MC63_RS10855	COG0500	methyltransferase
MC63_RS10870	COG3443	Belongs to the bacterial solute-binding protein 9 family
MC63_RS10885	COG2351	hydroxyisourate hydrolase activity
MC63_RS10890	COG0745	RESPONSE REGULATOR receiver
MC63_RS10895	COG2205	protein histidine kinase activity
MC63_RS10945	COG0270	DNA (cytosine-5-)-methyltransferase activity
MC63_RS10950	COG3727	T/G mismatch-specific endonuclease activity
MC63_RS10955	COG0697	spore germination
MC63_RS10960	COG2354	Protein conserved in bacteria
MC63_RS10965	COG5475	Uncharacterized small protein (DUF2158)
MC63_RS11000	COG2197	response regulator
MC63_RS11005	COG1684	flagellar biosynthetic protein fliR
MC63_RS11010	COG1987	bacterial-type flagellum assembly
MC63_RS11015	COG1338	Plays a role in the flagellum-specific transport system
MC63_RS11020	COG3190	flagellar
MC63_RS11025	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MC63_RS11030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MC63_RS11035	COG1580	Controls the rotational direction of flagella during chemotaxis
MC63_RS11040	COG3144	bacterial-type flagellum assembly
MC63_RS11045	COG2882	bacterial-type flagellum organization
MC63_RS11050	COG1157	protein secretion by the type III secretion system
MC63_RS11055	COG1317	bacterial-type flagellum organization
MC63_RS11060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MC63_RS11085	COG2076	Multidrug Resistance protein
MC63_RS11090	COG1881	PFAM PEBP family protein
MC63_RS11135	COG0675	Transposase, IS605 OrfB family
MC63_RS11140	COG0675	Transposase, IS605 OrfB family
MC63_RS11150	COG0425	Belongs to the sulfur carrier protein TusA family
MC63_RS11155	COG2391	methyltransferase activity
MC63_RS11165	COG0366	Alpha amylase catalytic
MC63_RS11175	COG1516	flagellar protein fliS
MC63_RS11180	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MC63_RS11190	COG1191	sigma factor activity
MC63_RS11200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC63_RS11210	COG0765	amino acid transport
MC63_RS11215	COG1126	abc transporter atp-binding protein
MC63_RS11220	COG2197	response regulator
MC63_RS11235	COG2197	response regulator
MC63_RS11265	COG3318	Belongs to the UPF0149 family
MC63_RS11265	COG3012	SEC-C Motif Domain Protein
MC63_RS11270	COG0814	amino acid
MC63_RS11280	COG1528	Iron-storage protein
MC63_RS11300	COG1528	Iron-storage protein
MC63_RS11305	COG1879	ABC-type sugar transport system periplasmic component
MC63_RS11325	COG3102	Protein conserved in bacteria
MC63_RS11335	COG3005	denitrification pathway
MC63_RS11340	COG0243	molybdopterin cofactor binding
MC63_RS11355	COG3788	relative of glutathione S-transferase, MAPEG superfamily
MC63_RS11360	COG1801	Protein of unknown function DUF72
MC63_RS11440	COG1801	Protein of unknown function DUF72
MC63_RS11490	COG3547	Transposase (IS116 IS110 IS902 family)
MC63_RS11620	COG3547	Transposase (IS116 IS110 IS902 family)
MC63_RS11625	COG1335	isochorismatase
MC63_RS11635	COG0494	nUDIX hydrolase
MC63_RS11640	COG0217	transcriptional regulatory protein
MC63_RS11665	COG3436	PFAM IS66 Orf2 family protein
MC63_RS11670	COG4372	Transposase
MC63_RS11705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MC63_RS11715	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
MC63_RS11720	COG0739	heme binding
MC63_RS11730	COG0469	pyruvate kinase activity
MC63_RS11735	COG1737	Transcriptional regulator
MC63_RS11740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MC63_RS11745	COG0129	dihydroxy-acid dehydratase activity
MC63_RS11750	COG0800	Aldolase
MC63_RS11770	COG2979	Protein of unknown function (DUF533)
MC63_RS11775	COG1770	oligopeptidase
MC63_RS11780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MC63_RS11785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC63_RS11795	COG2372	response to copper ion
MC63_RS11810	COG0582	viral genome integration into host DNA
MC63_RS11860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MC63_RS11890	COG1956	GAF domain-containing protein
MC63_RS11900	COG0793	Belongs to the peptidase S41A family
MC63_RS11910	COG2814	Major facilitator Superfamily
MC63_RS11915	COG1414	Transcriptional regulator
MC63_RS11945	COG2226	methyltransferase
MC63_RS11965	COG3716	PTS system mannose fructose sorbose family IID component
MC63_RS11970	COG3715	PTS system
MC63_RS11975	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS11975	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MC63_RS11980	COG1253	flavin adenine dinucleotide binding
MC63_RS11985	COG2200	EAL domain
MC63_RS12000	COG1760	l-serine dehydratase
MC63_RS12010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MC63_RS12030	COG0251	oxidation-reduction process
MC63_RS12035	COG1199	ATP-dependent helicase activity
MC63_RS12040	COG1214	PFAM Peptidase M22, glycoprotease
MC63_RS12045	COG3065	identical protein binding
MC63_RS12050	COG0318	PFAM AMP-dependent synthetase and ligase
MC63_RS12055	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MC63_RS12060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC63_RS12065	COG4638	Rieske (2fe-2S)
MC63_RS12095	COG2203	Gaf domain
MC63_RS12095	COG2199	diguanylate cyclase activity
MC63_RS12100	COG3042	response to heat
MC63_RS12105	COG3189	MarR family transcriptional regulator
MC63_RS12115	COG2807	transmembrane transport
MC63_RS12120	COG2207	Transcriptional regulator
MC63_RS12135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MC63_RS12140	COG2199	diguanylate cyclase activity
MC63_RS12160	COG2199	diguanylate cyclase activity
MC63_RS12170	COG2766	serine protein kinase
MC63_RS12175	COG3713	MltA-interacting MipA family protein
MC63_RS12180	COG0656	L-ascorbic acid biosynthetic process
MC63_RS12185	COG0676	glucose-6-phosphate 1-epimerase activity
MC63_RS12190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MC63_RS12200	COG3139	Protein of unknown function (DUF1315)
MC63_RS12205	COG1063	alcohol dehydrogenase
MC63_RS12210	COG2271	Major facilitator Superfamily
MC63_RS12220	COG0191	fructose-bisphosphate aldolase activity
MC63_RS12230	COG0667	Aldo Keto reductase
MC63_RS12235	COG1349	DNA-binding transcription factor activity
MC63_RS12240	COG2814	Major facilitator Superfamily
MC63_RS12245	COG1335	isochorismatase
MC63_RS12250	COG0252	asparaginase activity
MC63_RS12255	COG0616	signal peptide processing
MC63_RS12260	COG0778	Nitroreductase
MC63_RS12270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MC63_RS12280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MC63_RS12290	COG0494	nUDIX hydrolase
MC63_RS12295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MC63_RS12300	COG2897	thiosulfate sulfurtransferase activity
MC63_RS12305	COG4136	ATPase activity
MC63_RS12320	COG3385	transposase activity
MC63_RS12325	COG4134	Bacterial extracellular solute-binding protein
MC63_RS12330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MC63_RS12335	COG0398	Pfam SNARE associated Golgi protein
MC63_RS12345	COG0398	Pfam SNARE associated Golgi protein
MC63_RS12350	COG0708	Exodeoxyribonuclease III
MC63_RS12385	COG3678	ATP-independent chaperone mediated protein folding
MC63_RS12405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC63_RS12415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MC63_RS12420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MC63_RS12425	COG1447	Phosphotransferase system cellobiose-specific component IIA
MC63_RS12445	COG1486	melibiose metabolic process
MC63_RS12455	COG0753	catalase activity
MC63_RS12475	COG1988	membrane-bound metal-dependent
MC63_RS12490	COG3001	Fructosamine kinase
MC63_RS12500	COG1105	Belongs to the carbohydrate kinase PfkB family
MC63_RS12570	COG0386	Belongs to the glutathione peroxidase family
MC63_RS12580	COG0791	NLP P60 protein
MC63_RS12595	COG4256	Hemin uptake protein
MC63_RS12610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MC63_RS12610	COG0574	Belongs to the PEP-utilizing enzyme family
MC63_RS12620	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MC63_RS12625	COG0644	oxidoreductase
MC63_RS12630	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MC63_RS12635	COG2086	electron transfer activity
MC63_RS12655	COG2271	Major facilitator Superfamily
MC63_RS12660	COG0738	Major facilitator superfamily
MC63_RS12675	COG0628	permease
MC63_RS12680	COG0277	FAD linked oxidase domain protein
MC63_RS12680	COG0247	lactate metabolic process
MC63_RS12685	COG2050	protein possibly involved in aromatic compounds catabolism
MC63_RS12695	COG0316	Belongs to the HesB IscA family
MC63_RS12700	COG0719	Fe-S assembly protein
MC63_RS12705	COG0396	ATPase activity
MC63_RS12710	COG0719	Fe-S assembly protein
MC63_RS12725	COG1376	ErfK ybiS ycfS ynhG family protein
MC63_RS12730	COG4238	major outer membrane lipoprotein
MC63_RS12740	COG0469	pyruvate kinase activity
MC63_RS12760	COG0437	4 iron, 4 sulfur cluster binding
MC63_RS12765	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
MC63_RS12785	COG4529	Protein conserved in bacteria
MC63_RS12805	COG3468	outer membrane autotransporter barrel domain protein
MC63_RS12815	COG0307	riboflavin synthase, alpha
MC63_RS12820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MC63_RS12825	COG2814	Major facilitator Superfamily
MC63_RS12830	COG0583	DNA-binding transcription factor activity
MC63_RS12850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MC63_RS12855	COG0791	NLP P60 protein
MC63_RS12860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MC63_RS12870	COG0675	Transposase, IS605 OrfB family
MC63_RS12885	COG0346	lactoylglutathione lyase activity
MC63_RS12890	COG1902	pentaerythritol trinitrate reductase activity
MC63_RS12895	COG1309	transcriptional regulator
MC63_RS12900	COG3313	Fe-S protein
MC63_RS12905	COG4989	oxidoreductase activity
MC63_RS12910	COG2032	superoxide dismutase activity
MC63_RS12920	COG1566	PFAM secretion protein HlyD family protein
MC63_RS12935	COG3133	Outer membrane lipoprotein
MC63_RS12945	COG3895	Periplasmic Protein
MC63_RS12965	COG0625	glutathione transferase activity
MC63_RS12970	COG3104	oligopeptide transport
MC63_RS12980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MC63_RS12990	COG4659	FMN binding
MC63_RS13030	COG0673	inositol 2-dehydrogenase activity
MC63_RS13040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MC63_RS13045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MC63_RS13045	COG1263	PTS System
MC63_RS13050	COG1609	Transcriptional regulator
MC63_RS13070	COG1309	transcriptional regulator
MC63_RS13075	COG3250	beta-galactosidase activity
MC63_RS13090	COG5339	Protein conserved in bacteria
MC63_RS13100	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MC63_RS13100	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MC63_RS13115	COG2205	protein histidine kinase activity
MC63_RS13125	COG0745	RESPONSE REGULATOR receiver
MC63_RS13130	COG3136	membrane protein required for alginate biosynthesis
MC63_RS13140	COG0531	amino acid
MC63_RS13150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MC63_RS13155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MC63_RS13160	COG0628	permease
MC63_RS13180	COG3591	Belongs to the peptidase S1B family
MC63_RS13205	COG0583	DNA-binding transcription factor activity
MC63_RS13210	COG1940	carbohydrate kinase activity
MC63_RS13215	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MC63_RS13225	COG3381	protein complex oligomerization
MC63_RS13230	COG3302	dmso reductase anchor subunit
MC63_RS13235	COG0437	4 iron, 4 sulfur cluster binding
MC63_RS13345	COG3781	membrane
MC63_RS13370	COG2199	diguanylate cyclase activity
MC63_RS13425	COG1846	Transcriptional regulator
MC63_RS13430	COG4977	sequence-specific DNA binding
MC63_RS13440	COG0697	spore germination
MC63_RS13445	COG2814	Major facilitator Superfamily
MC63_RS13460	COG0339	signal peptide processing
MC63_RS13465	COG4221	oxidoreductase activity
MC63_RS13470	COG1802	Transcriptional regulator
MC63_RS13480	COG0246	Mannitol dehydrogenase
MC63_RS13490	COG1073	alpha beta
MC63_RS13495	COG1073	alpha beta
MC63_RS13500	COG3547	Transposase (IS116 IS110 IS902 family)
MC63_RS13505	COG1073	alpha beta
MC63_RS13515	COG2866	Carboxypeptidase
MC63_RS13520	COG4948	Mandelate Racemase Muconate Lactonizing
MC63_RS13525	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MC63_RS13530	COG3283	Transcriptional regulator of aromatic amino acids metabolism
MC63_RS13540	COG3106	COG3106 Predicted ATPase
MC63_RS13545	COG1609	Transcriptional regulator
MC63_RS13555	COG3842	ATPase activity
MC63_RS13560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC63_RS13640	COG1484	DNA-dependent DNA replication
MC63_RS13645	COG3756	Protein conserved in bacteria
MC63_RS13700	COG0484	heat shock protein binding
MC63_RS13705	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MC63_RS13710	COG1403	HNH endonuclease
MC63_RS13730	COG2026	Addiction module toxin, RelE StbE family
MC63_RS13735	COG3077	Addiction module antitoxin, RelB DinJ family
MC63_RS13755	COG3539	Fimbrial protein
MC63_RS13780	COG3539	Fimbrial protein
MC63_RS13815	COG4178	(ABC) transporter
MC63_RS13825	COG4771	TonB-dependent receptor
MC63_RS13830	COG0612	Peptidase, M16
MC63_RS13840	COG0076	glutamate decarboxylase activity
MC63_RS13845	COG0531	amino acid
MC63_RS13850	COG1649	PFAM Uncharacterised BCR, COG1649
MC63_RS13870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC63_RS13875	COG0444	Belongs to the ABC transporter superfamily
MC63_RS13885	COG1764	response to oxidative stress
MC63_RS13900	COG1064	alcohol dehydrogenase
MC63_RS13905	COG3093	addiction module antidote protein HigA
MC63_RS13910	COG2864	formate dehydrogenase
MC63_RS13915	COG0437	4 iron, 4 sulfur cluster binding
MC63_RS13925	COG0697	spore germination
MC63_RS13945	COG4886	Leucine-rich repeat (LRR) protein
MC63_RS13960	COG1140	nitrate reductase beta subunit
MC63_RS13975	COG4372	Transposase
MC63_RS13980	COG3436	PFAM IS66 Orf2 family protein
MC63_RS13995	COG1802	Transcriptional regulator
MC63_RS14000	COG2130	NADP-dependent
MC63_RS14015	COG1247	-acetyltransferase
MC63_RS14020	COG3238	Protein conserved in bacteria
MC63_RS14050	COG1177	transmembrane transport
MC63_RS14085	COG0500	methyltransferase
MC63_RS14090	COG1275	C4-dicarboxylate transporter malic acid transport protein
MC63_RS14095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MC63_RS14100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MC63_RS14105	COG2841	Protein conserved in bacteria
MC63_RS14120	COG0583	DNA-binding transcription factor activity
MC63_RS14150	COG3385	transposase activity
MC63_RS14185	COG3038	cytochrome b561
MC63_RS14190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MC63_RS14195	COG1012	belongs to the aldehyde dehydrogenase family
MC63_RS14215	COG3784	Protein of unknown function (DUF1318)
MC63_RS14225	COG2911	Protein conserved in bacteria
MC63_RS14230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MC63_RS14240	COG3042	response to heat
MC63_RS14245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC63_RS14245	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MC63_RS14245	COG1013	pyruvate-flavodoxin oxidoreductase activity
MC63_RS14245	COG0674	pyruvate-flavodoxin oxidoreductase activity
MC63_RS14255	COG0589	response to stress
MC63_RS14265	COG0513	Belongs to the DEAD box helicase family
MC63_RS14280	COG2840	Smr protein MutS2
MC63_RS14310	COG2207	Transcriptional regulator
MC63_RS14320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MC63_RS14325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MC63_RS14330	COG0589	response to stress
MC63_RS14360	COG0668	transmembrane transport
MC63_RS14365	COG4166	transmembrane transport
MC63_RS14380	COG1121	(ABC) transporter
MC63_RS14385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MC63_RS14390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MC63_RS14395	COG4372	Transposase
MC63_RS14400	COG3436	PFAM IS66 Orf2 family protein
MC63_RS14420	COG1643	Atp-dependent helicase
MC63_RS14445	COG3772	lysozyme
MC63_RS14520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MC63_RS14530	COG1983	PspC domain protein
MC63_RS14540	COG1842	Phage shock protein A
MC63_RS14545	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MC63_RS14550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MC63_RS14555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC63_RS14560	COG1012	belongs to the aldehyde dehydrogenase family
MC63_RS14565	COG1917	Cupin 2, conserved barrel domain protein
MC63_RS14565	COG1396	sequence-specific DNA binding
MC63_RS14575	COG0174	glutamine synthetase
MC63_RS14585	COG0531	amino acid
MC63_RS14595	COG4166	transmembrane transport
MC63_RS14600	COG4168	peptide transport system, permease
MC63_RS14605	COG4171	peptide transport system, permease
MC63_RS14610	COG4172	Belongs to the ABC transporter superfamily
MC63_RS14615	COG4172	Belongs to the ABC transporter superfamily
MC63_RS14620	COG2852	Protein conserved in bacteria
MC63_RS14625	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MC63_RS14630	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MC63_RS14630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MC63_RS14655	COG1349	DNA-binding transcription factor activity
MC63_RS14670	COG0023	Translation Initiation Factor
MC63_RS14680	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MC63_RS14685	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
MC63_RS14690	COG0671	phosphoesterase, PA-phosphatase related
MC63_RS14700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MC63_RS14725	COG0583	DNA-binding transcription factor activity
MC63_RS14730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MC63_RS14740	COG0616	signal peptide processing
MC63_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
MC63_RS14750	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
MC63_RS14755	COG1187	pseudouridine synthase activity
MC63_RS14760	COG0009	L-threonylcarbamoyladenylate synthase
MC63_RS14765	COG0613	PHP domain protein
MC63_RS14770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MC63_RS14775	COG0512	Glutamine amidotransferase of anthranilate synthase
MC63_RS14775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MC63_RS14780	COG0135	phosphoribosylanthranilate isomerase activity
MC63_RS14780	COG0134	indole-3-glycerol-phosphate synthase activity
MC63_RS14795	COG3729	General stress protein
MC63_RS14800	COG3685	Protein conserved in bacteria
MC63_RS14805	COG3685	Protein conserved in bacteria
MC63_RS14810	COG3047	cAMP biosynthetic process
MC63_RS14830	COG1607	acyl-coa hydrolase
MC63_RS14870	COG2350	Protein conserved in bacteria
MC63_RS14885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MC63_RS14905	COG4608	Belongs to the ABC transporter superfamily
MC63_RS14910	COG0444	Belongs to the ABC transporter superfamily
MC63_RS14915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC63_RS14920	COG0601	transmembrane transport
MC63_RS14925	COG4166	transmembrane transport
MC63_RS14930	COG2095	MarC family integral membrane protein
MC63_RS14935	COG1454	alcohol dehydrogenase
MC63_RS14935	COG1012	belongs to the aldehyde dehydrogenase family
MC63_RS14940	COG3385	transposase activity
MC63_RS14945	COG1435	thymidine kinase activity
MC63_RS14955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MC63_RS14960	COG0745	RESPONSE REGULATOR receiver
MC63_RS14965	COG1752	Esterase of the alpha-beta hydrolase superfamily
MC63_RS14975	COG0788	formyltetrahydrofolate deformylase activity
MC63_RS14995	COG2181	nitrate reductase activity
MC63_RS15000	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MC63_RS15005	COG1140	nitrate reductase beta subunit
MC63_RS15010	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MC63_RS15015	COG2223	nitrite transmembrane transporter activity
MC63_RS15020	COG3850	Histidine kinase
MC63_RS15025	COG2197	response regulator
MC63_RS15030	COG4932	domain protein
MC63_RS15035	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MC63_RS15040	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MC63_RS15045	COG4572	Cation transport regulator
MC63_RS15050	COG0387	Pfam Sodium calcium exchanger
MC63_RS15060	COG3385	transposase activity
MC63_RS15085	COG3094	Invasion gene expression up-regulator, SirB
MC63_RS15090	COG2890	protein-(glutamine-N5) methyltransferase activity
MC63_RS15115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MC63_RS15120	COG0659	secondary active sulfate transmembrane transporter activity
MC63_RS15135	COG0012	GTP binding
MC63_RS15150	COG3284	Transcriptional regulator
MC63_RS15155	COG2376	Dihydroxyacetone kinase
MC63_RS15160	COG1461	Dihydroxyacetone kinase
MC63_RS15190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MC63_RS15195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC63_RS15200	COG1120	ATPase activity
MC63_RS15205	COG0500	methyltransferase
MC63_RS15210	COG0157	Belongs to the NadC ModD family
MC63_RS15225	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MC63_RS15235	COG1619	proteins homologs of microcin C7 resistance protein MccF
MC63_RS15260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MC63_RS15270	COG2719	SpoVR family
MC63_RS15290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MC63_RS15295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MC63_RS15310	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC63_RS15355	COG2894	cell division
MC63_RS15445	COG2200	EAL domain
MC63_RS15455	COG5562	phage envelope protein
MC63_RS15470	COG0538	isocitrate dehydrogenase activity
MC63_RS15495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MC63_RS15520	COG1802	Transcriptional regulator
MC63_RS15520	COG4626	Terminase
MC63_RS15625	COG2850	peptidyl-arginine hydroxylation
MC63_RS15635	COG3842	ATPase activity
MC63_RS15645	COG1177	transmembrane transport
MC63_RS15650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MC63_RS15665	COG4591	ABC-type transport system involved in lipoprotein release permease component
MC63_RS15675	COG4591	ABC-type transport system involved in lipoprotein release permease component
MC63_RS15680	COG4763	Acyl-transferase
MC63_RS15685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MC63_RS15700	COG1309	transcriptional regulator
MC63_RS15705	COG3134	Outer membrane lipoprotein
MC63_RS15710	COG1252	NADH dehydrogenase
MC63_RS15730	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
MC63_RS15735	COG5633	Lipoprotein
MC63_RS15740	COG0537	adenosine 5'-monophosphoramidase activity
MC63_RS15750	COG1263	PTS System
MC63_RS15750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MC63_RS15755	COG0084	hydrolase, TatD family'
MC63_RS15760	COG0470	DNA polymerase III
MC63_RS15770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MC63_RS15775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MC63_RS15780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MC63_RS15790	COG1028	Short-chain dehydrogenase reductase Sdr
MC63_RS15795	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MC63_RS15815	COG1399	metal-binding, possibly nucleic acid-binding protein
MC63_RS15820	COG0424	maF-like protein
MC63_RS15825	COG0564	pseudouridine synthase activity
MC63_RS15835	COG1530	ribonuclease E activity
MC63_RS15840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MC63_RS15850	COG1705	Flagellar rod assembly protein muramidase FlgJ
MC63_RS15850	COG3951	Flagellar rod assembly protein muramidase FlgJ
MC63_RS15865	COG4786	Flagellar basal body rod
MC63_RS15875	COG1749	Flagellar hook protein flgE
MC63_RS15880	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MC63_RS15890	COG1815	bacterial-type flagellum-dependent cell motility
MC63_RS15895	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
MC63_RS15900	COG2747	anti-sigma28 factor FlgM
MC63_RS15905	COG3418	PFAM FlgN family protein
MC63_RS15910	COG0728	peptidoglycan biosynthetic process
MC63_RS15915	COG0673	inositol 2-dehydrogenase activity
MC63_RS15925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MC63_RS15935	COG2999	glutathione oxidoreductase activity
MC63_RS15970	COG3038	cytochrome b561
MC63_RS15985	COG1560	Kdo2-lipid A biosynthetic process
MC63_RS15995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MC63_RS16015	COG2943	transferase activity, transferring hexosyl groups
MC63_RS16035	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MC63_RS16070	COG2197	response regulator
MC63_RS16105	COG3381	protein complex oligomerization
MC63_RS16165	COG2003	Belongs to the UPF0758 family
MC63_RS16195	COG3468	outer membrane autotransporter barrel domain protein
MC63_RS16295	COG3436	PFAM IS66 Orf2 family protein
MC63_RS16300	COG4372	Transposase
MC63_RS16335	COG1595	DNA-templated transcription, initiation
MC63_RS16340	COG3712	iron ion homeostasis
MC63_RS16345	COG4772	TonB-dependent receptor
MC63_RS16350	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MC63_RS16355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC63_RS16360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC63_RS16365	COG1120	ATPase activity
MC63_RS16370	COG2085	NADP oxidoreductase coenzyme F420-dependent
MC63_RS16380	COG0726	polysaccharide deacetylase
MC63_RS16420	COG0640	Transcriptional regulator
MC63_RS16500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MC63_RS16510	COG0583	DNA-binding transcription factor activity
MC63_RS16565	COG0582	viral genome integration into host DNA
MC63_RS16590	COG1309	transcriptional regulator
MC63_RS16630	COG2233	PERMEase
MC63_RS16635	COG3729	General stress protein
MC63_RS16700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MC63_RS16705	COG0489	protein tyrosine kinase activity
MC63_RS16705	COG3206	protein involved in exopolysaccharide biosynthesis
MC63_RS16725	COG3436	PFAM IS66 Orf2 family protein
MC63_RS16775	COG3772	lysozyme
MC63_RS16790	COG4372	Transposase
MC63_RS16795	COG3436	PFAM IS66 Orf2 family protein
MC63_RS16805	COG0489	protein tyrosine kinase activity
MC63_RS16805	COG3206	protein involved in exopolysaccharide biosynthesis
MC63_RS16820	COG1294	oxidase, subunit
MC63_RS16825	COG1271	oxidase subunit
MC63_RS16830	COG1773	rubredoxin
MC63_RS16835	COG1999	signal sequence binding
MC63_RS16840	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MC63_RS16855	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
MC63_RS16865	COG0670	Belongs to the BI1 family
MC63_RS16870	COG2920	part of a sulfur-relay system
MC63_RS16875	COG1254	Belongs to the acylphosphatase family
MC63_RS16890	COG1832	CoA-binding protein
MC63_RS16905	COG0210	DNA helicase
MC63_RS16910	COG3304	Inner membrane component domain
MC63_RS16915	COG1289	transmembrane transporter activity
MC63_RS16920	COG3070	regulator of competence-specific genes
MC63_RS16940	COG1067	ATP-dependent peptidase activity
MC63_RS16950	COG3130	regulation of translation
MC63_RS16955	COG3009	Protein conserved in bacteria
MC63_RS16960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MC63_RS16960	COG3008	intermembrane lipid transfer
MC63_RS16965	COG2995	paraquat-inducible protein a
MC63_RS16980	COG3217	Mosc domain protein beta barrel domain protein
MC63_RS16980	COG0633	Ferredoxin
MC63_RS16995	COG3121	Chaperone
MC63_RS17000	COG3539	Fimbrial protein
MC63_RS17005	COG3539	Fimbrial protein
MC63_RS17010	COG3539	Fimbrial protein
MC63_RS17030	COG3539	Fimbrial protein
MC63_RS17040	COG0431	NADPH-dependent FMN reductase
MC63_RS17045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MC63_RS17055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC63_RS17065	COG0308	aminopeptidase N
MC63_RS17085	COG1448	Aminotransferase
MC63_RS17090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MC63_RS17095	COG3108	Peptidase M15
MC63_RS17100	COG2989	Protein conserved in bacteria
MC63_RS17105	COG3385	transposase activity
MC63_RS17115	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
MC63_RS17125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MC63_RS17130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MC63_RS17135	COG3173	Aminoglycoside phosphotransferase
MC63_RS17150	COG3214	Protein conserved in bacteria
MC63_RS17175	COG0539	negative regulation of cytoplasmic translation
MC63_RS17185	COG0501	Belongs to the peptidase M48B family
MC63_RS17190	COG3385	transposase activity
MC63_RS17210	COG1944	ATP diphosphatase activity
MC63_RS17215	COG2116	formate transmembrane transporter activity
MC63_RS17220	COG1882	Formate acetyltransferase
MC63_RS17225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MC63_RS17230	COG2249	NAD(P)H dehydrogenase (quinone) activity
MC63_RS17250	COG0583	DNA-binding transcription factor activity
MC63_RS17265	COG0531	amino acid
MC63_RS17270	COG4372	Transposase
MC63_RS17275	COG3436	PFAM IS66 Orf2 family protein
MC63_RS17295	COG1335	isochorismatase
MC63_RS17300	COG3302	dmso reductase anchor subunit
MC63_RS17305	COG0437	4 iron, 4 sulfur cluster binding
MC63_RS17320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MC63_RS17335	COG1522	sequence-specific DNA binding
MC63_RS17340	COG0492	ferredoxin-NADP+ reductase activity
MC63_RS17345	COG4988	ABC transporter
MC63_RS17350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MC63_RS17375	COG0542	response to heat
MC63_RS17385	COG1278	Cold shock
MC63_RS17395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC63_RS17400	COG2990	Protein conserved in bacteria
MC63_RS17405	COG3593	DNA synthesis involved in DNA repair
MC63_RS17420	COG2431	L-lysine efflux transmembrane transporter activity
MC63_RS17430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC63_RS17435	COG0028	Belongs to the TPP enzyme family
MC63_RS17440	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
MC63_RS17445	COG0702	epimerase
MC63_RS17450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC63_RS17455	COG3023	N-Acetylmuramoyl-L-alanine amidase
MC63_RS17485	COG1126	abc transporter atp-binding protein
MC63_RS17490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC63_RS17495	COG4215	(ABC) transporter
MC63_RS17500	COG4160	amino acid transport
MC63_RS17505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC63_RS17520	COG1177	transmembrane transport
MC63_RS17525	COG1176	ABC-type spermidine putrescine transport system, permease component I
MC63_RS17530	COG3842	ATPase activity
MC63_RS17535	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MC63_RS17550	COG0778	Nitroreductase
MC63_RS17560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MC63_RS17575	COG3226	Transcriptional regulator
MC63_RS17580	COG0738	Major facilitator superfamily
MC63_RS17585	COG0561	phosphatase activity
MC63_RS17600	COG0671	phosphoesterase, PA-phosphatase related
MC63_RS17605	COG1349	DNA-binding transcription factor activity
MC63_RS17620	COG1686	Belongs to the peptidase S11 family
MC63_RS17630	COG2133	pyrroloquinoline quinone binding
MC63_RS17635	COG2133	pyrroloquinoline quinone binding
MC63_RS17650	COG2199	diguanylate cyclase activity
MC63_RS17655	COG2200	EAL domain
MC63_RS17680	COG1446	asparaginase
MC63_RS17685	COG0303	'Molybdopterin
MC63_RS17690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MC63_RS17695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MC63_RS17700	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MC63_RS17705	COG1882	Formate acetyltransferase
MC63_RS17710	COG0561	phosphatase activity
MC63_RS17720	COG0488	(ABC) transporter
MC63_RS17725	COG1376	ErfK ybiS ycfS ynhG family protein
MC63_RS17730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MC63_RS17735	COG1321	iron dependent repressor
MC63_RS17745	COG2194	sulfuric ester hydrolase activity
MC63_RS17750	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MC63_RS17760	COG5006	permease, DMT superfamily
MC63_RS17770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC63_RS17775	COG0765	amino acid transport
MC63_RS17780	COG1126	abc transporter atp-binding protein
MC63_RS17820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MC63_RS17830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MC63_RS17835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MC63_RS17855	COG1309	transcriptional regulator
MC63_RS17865	COG1131	(ABC) transporter
MC63_RS17870	COG0842	Transport permease protein
MC63_RS17875	COG0842	Transport permease protein
MC63_RS17885	COG3568	Endonuclease Exonuclease Phosphatase
MC63_RS17890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC63_RS17895	COG0392	lysyltransferase activity
MC63_RS17910	COG0670	Belongs to the BI1 family
MC63_RS17915	COG0314	molybdopterin synthase activity
MC63_RS17920	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MC63_RS17930	COG0521	Mo-molybdopterin cofactor biosynthetic process
MC63_RS17940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MC63_RS17950	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MC63_RS17955	COG2226	methyltransferase
MC63_RS17970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MC63_RS17975	COG1881	PFAM PEBP family protein
MC63_RS17990	COG5434	Belongs to the glycosyl hydrolase 28 family
MC63_RS18105	COG1475	DNA binding
MC63_RS18125	COG0583	DNA-binding transcription factor activity
MC63_RS18130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MC63_RS18135	COG0450	alkyl hydroperoxide reductase
MC63_RS18140	COG3634	alkyl hydroperoxide reductase activity
MC63_RS18155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MC63_RS18160	COG3719	Belongs to the RNase T2 family
MC63_RS18165	COG0471	metal ion transport
MC63_RS18180	COG3051	citrate lyase alpha subunit
MC63_RS18185	COG2301	Belongs to the HpcH HpaI aldolase family
MC63_RS18195	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MC63_RS18220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MC63_RS18270	COG3069	C4-dicarboxylate transmembrane transporter activity
MC63_RS18290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC63_RS18295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MC63_RS18305	COG0583	DNA-binding transcription factor activity
MC63_RS18320	COG1686	Belongs to the peptidase S11 family
MC63_RS18325	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MC63_RS18330	COG0772	Belongs to the SEDS family
MC63_RS18335	COG0768	penicillin binding
MC63_RS18345	COG0799	negative regulation of ribosome biogenesis
MC63_RS18350	COG0406	alpha-ribazole phosphatase activity
MC63_RS18360	COG1466	dna polymerase III delta subunit
MC63_RS18375	COG2888	peptidyl-tyrosine sulfation
MC63_RS18380	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MC63_RS18390	COG2214	Heat shock protein DnaJ domain protein
MC63_RS18395	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MC63_RS18415	COG2214	Heat shock protein DnaJ domain protein
MC63_RS18420	COG0443	Heat shock 70 kDa protein
MC63_RS18430	COG1126	abc transporter atp-binding protein
MC63_RS18435	COG0765	amino acid transport
MC63_RS18440	COG0765	amino acid transport
MC63_RS18450	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MC63_RS18455	COG4535	Mg2 and Co2 transporter CorC
MC63_RS18465	COG1702	phosphate starvation-inducible protein PhoH
MC63_RS18475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC63_RS18515	COG0367	asparagine synthase
MC63_RS18525	COG1940	carbohydrate kinase activity
MC63_RS18525	COG1846	Transcriptional regulator
MC63_RS18530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MC63_RS18540	COG1263	PTS System
MC63_RS18540	COG2190	(PTS) system
MC63_RS18540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MC63_RS18560	COG0735	belongs to the Fur family
MC63_RS18570	COG0716	FMN binding
MC63_RS18580	COG0596	Alpha beta hydrolase
MC63_RS18585	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
MC63_RS18590	COG0033	Phosphoglucomutase
MC63_RS18595	COG0531	amino acid
MC63_RS18610	COG1982	Orn Lys Arg decarboxylase major
MC63_RS18625	COG0745	RESPONSE REGULATOR receiver
MC63_RS18675	COG3272	Protein of unknown function (DUF1722)
MC63_RS18680	COG0415	Belongs to the DNA photolyase family
MC63_RS18690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MC63_RS18695	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MC63_RS18700	COG1984	allophanate hydrolase subunit 2
MC63_RS18715	COG3180	Ammonia monooxygenase
MC63_RS18720	COG3539	Fimbrial protein
MC63_RS18725	COG3121	Chaperone
MC63_RS18730	COG3188	usher protein
MC63_RS18740	COG0372	Belongs to the citrate synthase family
MC63_RS18750	COG2009	succinate dehydrogenase
MC63_RS18755	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MC63_RS18760	COG1053	succinate dehydrogenase
MC63_RS18765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MC63_RS18770	COG0567	Dehydrogenase, E1 component
MC63_RS18775	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC63_RS18785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MC63_RS18790	COG2188	Transcriptional regulator
MC63_RS18795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MC63_RS18795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MC63_RS18795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS18810	COG1271	oxidase subunit
MC63_RS18815	COG1294	oxidase, subunit
MC63_RS18820	COG4890	Cyd operon protein YbgT
MC63_RS18825	COG3790	cyd operon protein YbgE
MC63_RS18830	COG0824	Thioesterase
MC63_RS18835	COG0811	peptide transport
MC63_RS18840	COG0848	biopolymer transport protein
MC63_RS18845	COG3064	Membrane
MC63_RS18855	COG2885	chlorophyll binding
MC63_RS18860	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MC63_RS18895	COG3201	nicotinamide mononucleotide transporter
MC63_RS18900	COG1230	cation diffusion facilitator family transporter
MC63_RS18910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MC63_RS18920	COG2017	converts alpha-aldose to the beta-anomer
MC63_RS18930	COG1085	galactose-1-phosphate uridylyltransferase
MC63_RS18935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MC63_RS18940	COG1119	ATPase activity
MC63_RS18945	COG3585	molybdate ion transport
MC63_RS18945	COG2005	Transcriptional regulator
MC63_RS18960	COG0725	ABC transporter, periplasmic molybdate-binding protein
MC63_RS18965	COG4149	molybdate abc transporter
MC63_RS18980	COG0582	viral genome integration into host DNA
MC63_RS19000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MC63_RS19050	COG0582	viral genome integration into host DNA
MC63_RS19055	COG4677	pectinesterase activity
MC63_RS19060	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MC63_RS19075	COG0471	metal ion transport
MC63_RS19080	COG2828	Protein conserved in bacteria
MC63_RS19150	COG2315	Protein conserved in bacteria
MC63_RS19155	COG0778	Nitroreductase
MC63_RS19160	COG0668	transmembrane transport
MC63_RS19165	COG1113	amino acid transport
MC63_RS19195	COG0745	RESPONSE REGULATOR receiver
MC63_RS19200	COG5002	protein histidine kinase activity
MC63_RS19210	COG1215	transferase activity, transferring glycosyl groups
MC63_RS19215	COG4783	chaperone-mediated protein folding
MC63_RS19225	COG2207	Transcriptional regulator
MC63_RS19245	COG3121	Chaperone
MC63_RS19250	COG3539	Fimbrial protein
MC63_RS19260	COG2501	S4 domain
MC63_RS19265	COG1988	membrane-bound metal-dependent
MC63_RS19275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MC63_RS19285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MC63_RS19290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MC63_RS19295	COG0549	Belongs to the carbamate kinase family
MC63_RS19305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC63_RS19310	COG3257	ureidoglycine aminohydrolase activity
MC63_RS19325	COG3960	tartronate-semialdehyde synthase activity
MC63_RS19330	COG1414	Transcriptional regulator
MC63_RS19340	COG0583	DNA-binding transcription factor activity
MC63_RS19350	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MC63_RS19355	COG4181	ATPase activity
MC63_RS19365	COG0300	oxidoreductase activity
MC63_RS19370	COG3118	belongs to the thioredoxin family
MC63_RS19375	COG0390	transport system, permease component
MC63_RS19380	COG4619	ABC transporter
MC63_RS19385	COG0330	HflC and HflK could
MC63_RS19390	COG1585	Membrane protein implicated in regulation of membrane protease activity
MC63_RS19395	COG0789	Transcriptional regulator
MC63_RS19400	COG0531	amino acid
MC63_RS19410	COG2217	Heavy metal translocating P-type atpase
MC63_RS19415	COG3093	addiction module antidote protein HigA
MC63_RS19425	COG3735	TraB family
MC63_RS19430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MC63_RS19435	COG0737	Belongs to the 5'-nucleotidase family
MC63_RS19455	COG4651	solute:proton antiporter activity
MC63_RS19455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MC63_RS19460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MC63_RS19495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MC63_RS19505	COG2832	Protein of unknown function (DUF454)
MC63_RS19510	COG3923	Primosomal replication protein n
MC63_RS19520	COG1196	nuclear chromosome segregation
MC63_RS19520	COG3264	Mechanosensitive ion channel
MC63_RS19525	COG1309	transcriptional regulator
MC63_RS19530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC63_RS19535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC63_RS19550	COG0110	maltose O-acetyltransferase activity
MC63_RS19560	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MC63_RS19565	COG5507	3-demethylubiquinone-9 3-methyltransferase
MC63_RS19575	COG3695	enzyme binding
MC63_RS19580	COG3385	transposase activity
MC63_RS19585	COG3126	Type III secretion system lipoprotein chaperone (YscW)
MC63_RS19595	COG0004	ammonium transporteR
MC63_RS19600	COG0347	Belongs to the P(II) protein family
MC63_RS19605	COG1132	(ABC) transporter
MC63_RS19610	COG1132	(ABC) transporter
MC63_RS19620	COG0561	phosphatase activity
MC63_RS19635	COG0824	Thioesterase
MC63_RS19640	COG1555	photosystem II stabilization
MC63_RS19645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC63_RS19650	COG0776	regulation of translation
MC63_RS19655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MC63_RS19675	COG0271	Belongs to the BolA IbaG family
MC63_RS19680	COG3056	Lipoprotein
MC63_RS19685	COG2223	nitrite transmembrane transporter activity
MC63_RS19695	COG3436	PFAM IS66 Orf2 family protein
MC63_RS19745	COG2246	polysaccharide biosynthetic process
MC63_RS19770	COG0582	viral genome integration into host DNA
MC63_RS19775	COG2246	polysaccharide biosynthetic process
MC63_RS19800	COG0247	lactate metabolic process
MC63_RS19805	COG1139	Iron-sulfur cluster binding protein
MC63_RS19810	COG1556	Lactate utilization protein
MC63_RS19825	COG3423	Transcriptional regulator
MC63_RS19860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC63_RS19865	COG2175	clavaminate synthase activity
MC63_RS19870	COG2175	clavaminate synthase activity
MC63_RS19875	COG0113	porphobilinogen synthase activity
MC63_RS19910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MC63_RS19915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MC63_RS19920	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MC63_RS19940	COG1181	Belongs to the D-alanine--D-alanine ligase family
MC63_RS19965	COG3706	GGDEF domain
MC63_RS19970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MC63_RS19990	COG4126	flavin adenine dinucleotide binding
MC63_RS20020	COG1940	carbohydrate kinase activity
MC63_RS20025	COG2814	Major facilitator Superfamily
MC63_RS20030	COG0419	ATPase involved in DNA repair
MC63_RS20035	COG0420	3'-5' exonuclease activity
MC63_RS20040	COG0745	RESPONSE REGULATOR receiver
MC63_RS20045	COG5002	protein histidine kinase activity
MC63_RS20050	COG1114	Component of the transport system for branched-chain amino acids
MC63_RS20055	COG1113	amino acid transport
MC63_RS20060	COG0366	Alpha amylase catalytic
MC63_RS20080	COG1862	Preprotein translocase
MC63_RS20085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MC63_RS20090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MC63_RS20095	COG1403	HNH endonuclease
MC63_RS20100	COG3248	Nucleoside-binding outer membrane protein
MC63_RS20105	COG4238	major outer membrane lipoprotein
MC63_RS20130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MC63_RS20135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MC63_RS20140	COG0667	Aldo Keto reductase
MC63_RS20150	COG0142	geranyltranstransferase activity
MC63_RS20165	COG0693	protein deglycase activity
MC63_RS20170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MC63_RS20190	COG2814	Major facilitator Superfamily
MC63_RS20225	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MC63_RS20230	COG1845	cytochrome c oxidase, subunit III
MC63_RS20235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MC63_RS20245	COG3436	PFAM IS66 Orf2 family protein
MC63_RS20250	COG4372	Transposase
MC63_RS20295	COG0582	viral genome integration into host DNA
MC63_RS20315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC63_RS20335	COG2195	Cleaves the N-terminal amino acid of tripeptides
MC63_RS20350	COG0454	-acetyltransferase
MC63_RS20365	COG2161	toxin-antitoxin pair type II binding
MC63_RS20385	COG1943	Transposase
MC63_RS20390	COG0791	NLP P60 protein
MC63_RS20395	COG3034	peptidoglycan biosynthetic process
MC63_RS20400	COG0121	glutamine amidotransferase
MC63_RS20410	COG1960	acyl-CoA dehydrogenase activity
MC63_RS20420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC63_RS20525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MC63_RS20535	COG2226	methyltransferase
MC63_RS20545	COG0741	lytic transglycosylase activity
MC63_RS20545	COG1388	LysM domain
MC63_RS20550	COG2226	methyltransferase
MC63_RS20565	COG3385	transposase activity
MC63_RS20570	COG0656	L-ascorbic acid biosynthetic process
MC63_RS20605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MC63_RS20610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MC63_RS20615	COG2011	ABC-type metal ion transport system permease component
MC63_RS20620	COG1464	Belongs to the NlpA lipoprotein family
MC63_RS20630	COG1720	tRNA m6t6A37 methyltransferase activity
MC63_RS20640	COG0791	NLP P60 protein
MC63_RS20645	COG3015	lipoprotein NlpE involved in copper resistance
MC63_RS20650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MC63_RS20655	COG4681	YaeQ
MC63_RS20665	COG4568	rho-dependent transcription termination
MC63_RS20675	COG0346	lactoylglutathione lyase activity
MC63_RS20680	COG1982	Orn Lys Arg decarboxylase major
MC63_RS20690	COG0587	DNA-directed DNA polymerase activity
MC63_RS20715	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MC63_RS20720	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
MC63_RS20730	COG0750	zinc metalloprotease
MC63_RS20735	COG0575	Belongs to the CDS family
MC63_RS20740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MC63_RS20770	COG0024	Methionine aminopeptidase
MC63_RS20795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MC63_RS20815	COG2860	membrane
MC63_RS20840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC63_RS20845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MC63_RS20850	COG1120	ATPase activity
MC63_RS20855	COG4774	siderophore transport
MC63_RS20860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MC63_RS20865	COG1643	Atp-dependent helicase
MC63_RS20870	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MC63_RS20880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MC63_RS20890	COG0617	tRNA 3'-terminal CCA addition
MC63_RS20895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MC63_RS20920	COG5464	transposase or invertase
MC63_RS20930	COG0726	polysaccharide deacetylase
MC63_RS20940	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC63_RS20945	COG0842	Transport permease protein
MC63_RS20950	COG1131	(ABC) transporter
MC63_RS20955	COG0288	reversible hydration of carbon dioxide
MC63_RS20960	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MC63_RS20965	COG4993	Dehydrogenase
MC63_RS20995	COG1049	propionate catabolic process, 2-methylcitrate cycle
MC63_RS21000	COG3064	Membrane
MC63_RS21005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC63_RS21010	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC63_RS21015	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MC63_RS21020	COG2186	Transcriptional regulator
MC63_RS21030	COG3725	Membrane protein required for beta-lactamase induction
MC63_RS21035	COG3023	N-Acetylmuramoyl-L-alanine amidase
MC63_RS21040	COG0157	Belongs to the NadC ModD family
MC63_RS21045	COG4969	Belongs to the N-Me-Phe pilin family
MC63_RS21050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MC63_RS21055	COG1459	type II secretion system
MC63_RS21080	COG0494	nUDIX hydrolase
MC63_RS21100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MC63_RS21105	COG0849	cell division
MC63_RS21110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MC63_RS21130	COG0772	Belongs to the SEDS family
MC63_RS21135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MC63_RS21145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MC63_RS21155	COG0768	penicillin binding
MC63_RS21160	COG3116	cell division
MC63_RS21180	COG1609	Transcriptional regulator
MC63_RS21190	COG0440	acetolactate synthase activity
MC63_RS21200	COG0583	DNA-binding transcription factor activity
MC63_RS21230	COG2814	Major facilitator Superfamily
MC63_RS21245	COG4143	(ABC) transporter
MC63_RS21250	COG1178	ABC-type Fe3 transport system permease component
MC63_RS21260	COG0586	Pfam SNARE associated Golgi protein
MC63_RS21265	COG4977	sequence-specific DNA binding
MC63_RS21280	COG0235	Class ii aldolase
MC63_RS21285	COG0417	DNA replication proofreading
MC63_RS21295	COG0564	pseudouridine synthase activity
MC63_RS21300	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MC63_RS21310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC63_RS21335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MC63_RS21350	COG2271	Major facilitator Superfamily
MC63_RS21360	COG0644	oxidoreductase
MC63_RS21410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MC63_RS21415	COG0505	Belongs to the CarA family
MC63_RS21435	COG1047	Peptidyl-prolyl cis-trans
MC63_RS21450	COG0196	riboflavin kinase activity
MC63_RS21475	COG0583	DNA-binding transcription factor activity
MC63_RS21505	COG4735	regulation of single-species biofilm formation
MC63_RS21510	COG1584	GPR1 FUN34 yaaH family protein
MC63_RS21515	COG0521	Mo-molybdopterin cofactor biosynthetic process
MC63_RS21520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MC63_RS21540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MC63_RS21550	COG0460	homoserine dehydrogenase
MC63_RS21550	COG0527	aspartate kinase activity
MC63_RS21560	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MC63_RS21570	COG0745	RESPONSE REGULATOR receiver
MC63_RS21575	COG4452	Inner membrane protein CreD
MC63_RS21580	COG2205	protein histidine kinase activity
MC63_RS21585	COG0745	RESPONSE REGULATOR receiver
MC63_RS21590	COG3045	CreA protein
MC63_RS21595	COG2207	Transcriptional regulator
MC63_RS21595	COG3708	Transcriptional regulator
MC63_RS21615	COG0741	lytic transglycosylase activity
MC63_RS21620	COG0488	(ABC) transporter
MC63_RS21625	COG3172	ATPase kinase involved in NAD metabolism
MC63_RS21625	COG1056	cytidyltransferase-related domain
MC63_RS21630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MC63_RS21635	COG0560	Phosphoserine phosphatase
MC63_RS21640	COG3726	membrane protein affecting hemolysin expression
MC63_RS21675	COG1328	CTP reductase activity
MC63_RS21680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MC63_RS21685	COG0084	hydrolase, TatD family'
MC63_RS21690	COG4667	esterase of the alpha-beta hydrolase superfamily
MC63_RS21700	COG2823	Periplasmic or secreted lipoprotein
MC63_RS21710	COG1011	Hydrolase
MC63_RS21715	COG0456	acetyltransferase
MC63_RS21720	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
MC63_RS21750	COG4114	ferric iron reductase
MC63_RS21760	COG2197	response regulator
MC63_RS21770	COG2966	Psort location CytoplasmicMembrane, score
MC63_RS21785	COG1484	DNA-dependent DNA replication
MC63_RS21810	COG2271	Major facilitator Superfamily
MC63_RS21815	COG0840	transmembrane signaling receptor activity
MC63_RS21820	COG1846	Transcriptional regulator
MC63_RS21825	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC63_RS21830	COG1012	belongs to the aldehyde dehydrogenase family
MC63_RS21835	COG3384	dioxygenase
MC63_RS21845	COG3971	2-oxopent-4-enoate hydratase activity
MC63_RS21850	COG3385	transposase activity
MC63_RS21880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC63_RS21885	COG1966	Carbon starvation protein
MC63_RS21890	COG2879	small protein
MC63_RS21895	COG0523	cobalamin synthesis protein
MC63_RS21915	COG0732	type I restriction modification DNA specificity domain
MC63_RS21940	COG0440	acetolactate synthase activity
MC63_RS21945	COG1349	DNA-binding transcription factor activity
MC63_RS21985	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MC63_RS21995	COG4974	Belongs to the 'phage' integrase family
MC63_RS22005	COG3539	Fimbrial protein
MC63_RS22015	COG3188	usher protein
MC63_RS22020	COG3539	Fimbrial protein
MC63_RS22025	COG3539	Fimbrial protein
MC63_RS22030	COG3539	Fimbrial protein
MC63_RS22035	COG2610	gluconate transmembrane transporter activity
MC63_RS22045	COG0246	Mannitol dehydrogenase
MC63_RS22050	COG2186	Transcriptional regulator
MC63_RS22070	COG0583	DNA-binding transcription factor activity
MC63_RS22075	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MC63_RS22080	COG0700	Nucleoside recognition
MC63_RS22085	COG3366	ferrous iron transmembrane transporter activity
MC63_RS22100	COG3592	Divergent 4Fe-4S mono-cluster
MC63_RS22115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MC63_RS22120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MC63_RS22120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MC63_RS22125	COG3647	Membrane
MC63_RS22135	COG2211	Major facilitator Superfamily
MC63_RS22140	COG1486	melibiose metabolic process
MC63_RS22145	COG2169	Transcriptional regulator
MC63_RS22155	COG1982	Orn Lys Arg decarboxylase major
MC63_RS22160	COG2207	Transcriptional regulator
MC63_RS22165	COG0531	amino acid
MC63_RS22170	COG2194	sulfuric ester hydrolase activity
MC63_RS22175	COG0745	RESPONSE REGULATOR receiver
MC63_RS22180	COG0642	Histidine kinase
MC63_RS22190	COG0477	Major facilitator Superfamily
MC63_RS22200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MC63_RS22205	COG2824	Alkylphosphonate utilization operon protein PhnA
MC63_RS22210	COG2764	glyoxalase bleomycin resistance protein dioxygenase
MC63_RS22220	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MC63_RS22225	COG3639	organic phosphonate transmembrane transporter activity
MC63_RS22230	COG2188	Transcriptional regulator
MC63_RS22235	COG3624	Phosphonate C-P lyase system protein PhnG
MC63_RS22240	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
MC63_RS22245	COG3626	phosphonate metabolism
MC63_RS22250	COG3627	carbon phosphorus lyase activity
MC63_RS22255	COG4107	phosphonate C-P lyase system protein PhnK
MC63_RS22260	COG4778	phosphonate C-P lyase system protein PhnL
MC63_RS22265	COG3454	Phosphonate metabolism
MC63_RS22270	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MC63_RS22275	COG0456	acetyltransferase
MC63_RS22305	COG1129	ABC transporter
MC63_RS22310	COG1172	Belongs to the binding-protein-dependent transport system permease family
MC63_RS22315	COG1879	ABC-type sugar transport system periplasmic component
MC63_RS22330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MC63_RS22350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MC63_RS22355	COG0557	exoribonuclease II activity
MC63_RS22370	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
MC63_RS22375	COG0330	HflC and HflK could
MC63_RS22380	COG0330	HflC and HflK could
MC63_RS22385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MC63_RS22405	COG0860	N-Acetylmuramoyl-L-alanine amidase
MC63_RS22410	COG0802	atpase or kinase
MC63_RS22415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MC63_RS22415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MC63_RS22420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MC63_RS22465	COG3264	Mechanosensitive ion channel
MC63_RS22465	COG1511	domain protein
MC63_RS22470	COG0531	amino acid
MC63_RS22480	COG1053	succinate dehydrogenase
MC63_RS22485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MC63_RS22500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MC63_RS22505	COG3040	lipid binding
MC63_RS22515	COG5510	response to toxic substance
MC63_RS22520	COG5510	response to toxic substance
MC63_RS22530	COG1509	lysine 2,3-aminomutase activity
MC63_RS22565	COG0531	amino acid
MC63_RS22570	COG3030	protein affecting phage T7 exclusion by the F plasmid
MC63_RS22575	COG1027	Aspartate ammonia-lyase
MC63_RS22580	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MC63_RS22595	COG1309	transcriptional regulator
MC63_RS22615	COG0545	Peptidyl-prolyl cis-trans isomerase
MC63_RS22620	COG1113	amino acid transport
MC63_RS22630	COG0697	spore germination
MC63_RS22635	COG0702	epimerase
MC63_RS22640	COG1733	regulation of RNA biosynthetic process
MC63_RS22675	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
MC63_RS22685	COG1253	flavin adenine dinucleotide binding
MC63_RS22695	COG0729	surface antigen
MC63_RS22700	COG2911	Protein conserved in bacteria
MC63_RS22705	COG2105	PFAM AIG2 family protein
MC63_RS22710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MC63_RS22720	COG1129	ABC transporter
MC63_RS22725	COG1172	Belongs to the binding-protein-dependent transport system permease family
MC63_RS22730	COG1172	Belongs to the binding-protein-dependent transport system permease family
MC63_RS22735	COG3385	transposase activity
MC63_RS22745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MC63_RS22755	COG0312	modulator of DNA gyrase
MC63_RS22760	COG3783	Cytochrome b(562)
MC63_RS22765	COG0602	queuosine metabolic process
MC63_RS22770	COG1328	CTP reductase activity
MC63_RS22775	COG0366	Alpha amylase catalytic
MC63_RS22785	COG1609	Transcriptional regulator
MC63_RS22795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MC63_RS22800	COG0251	oxidation-reduction process
MC63_RS22820	COG0251	oxidation-reduction process
MC63_RS22825	COG1028	Short-chain dehydrogenase reductase Sdr
MC63_RS22830	COG1309	transcriptional regulator
MC63_RS22835	COG2731	YhcH YjgK YiaL family protein
MC63_RS22850	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
MC63_RS22855	COG0456	acetyltransferase
MC63_RS22875	COG2927	DNA polymerase III (CHI subunit)
MC63_RS22885	COG0795	lipopolysaccharide-transporting ATPase activity
MC63_RS22890	COG0795	lipopolysaccharide-transporting ATPase activity
MC63_RS22895	COG0433	COG0433 Predicted ATPase
MC63_RS22900	COG1064	alcohol dehydrogenase
MC63_RS22915	COG4372	Transposase
MC63_RS22920	COG3436	PFAM IS66 Orf2 family protein
MC63_RS22940	COG2388	GCN5-related N-acetyl-transferase
MC63_RS22975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MC63_RS23035	COG1073	alpha beta
MC63_RS23040	COG3650	response to hydrogen peroxide
MC63_RS23055	COG0754	glutathionylspermidine amidase activity
MC63_RS23060	COG5463	Belongs to the UPF0441 family
MC63_RS23065	COG3766	membrane
MC63_RS23105	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MC63_RS23110	COG1301	dicarboxylic acid transport
MC63_RS23115	COG4235	cytochrome complex assembly
MC63_RS23120	COG3088	subunit of a heme lyase
MC63_RS23125	COG1138	Cytochrome C-type biogenesis protein
MC63_RS23130	COG3301	Polysulphide reductase, NrfD
MC63_RS23135	COG0437	4 iron, 4 sulfur cluster binding
MC63_RS23140	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
MC63_RS23150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MC63_RS23155	COG3162	membrane
MC63_RS23165	COG1357	PFAM Pentapeptide repeats (8 copies)
MC63_RS23170	COG0025	NhaP-type Na H and K H
MC63_RS23175	COG2252	PERMEase
MC63_RS23180	COG0789	Transcriptional regulator
MC63_RS23185	COG2207	Transcriptional regulator
MC63_RS23215	COG0629	single-stranded DNA binding
MC63_RS23220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MC63_RS23225	COG2315	Protein conserved in bacteria
MC63_RS23230	COG0432	Pfam Uncharacterised protein family UPF0047
MC63_RS23235	COG3700	Belongs to the class B bacterial acid phosphatase family
MC63_RS23245	COG1448	Aminotransferase
MC63_RS23250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MC63_RS23255	COG0305	Participates in initiation and elongation during chromosome replication
MC63_RS23260	COG0604	alcohol dehydrogenase
MC63_RS23270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MC63_RS23285	COG0735	belongs to the Fur family
MC63_RS23290	COG3237	CsbD-like
MC63_RS23295	COG0534	Mate efflux family protein
MC63_RS23305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MC63_RS23345	COG2182	Extracellular solute-binding protein
MC63_RS23355	COG3833	ABC-type maltose transport systems, permease component
MC63_RS23380	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC63_RS23415	COG0527	aspartate kinase activity
MC63_RS23490	COG1283	sodium-dependent phosphate transmembrane transporter activity
MC63_RS23555	COG3436	PFAM IS66 Orf2 family protein
MC63_RS23605	COG3436	PFAM IS66 Orf2 family protein
MC63_RS23695	COG3385	transposase activity
MC63_RS23725	COG0726	polysaccharide deacetylase
MC63_RS23730	COG0297	glycogen (starch) synthase activity
MC63_RS23735	COG2990	Protein conserved in bacteria
MC63_RS23785	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
MC63_RS23895	COG4372	Transposase
MC63_RS24120	COG3385	transposase activity
MC63_RS24130	COG3436	PFAM IS66 Orf2 family protein
MC63_RS24310	COG3547	Transposase (IS116 IS110 IS902 family)
MC63_RS24540	COG4372	Transposase
MC63_RS24545	COG3436	PFAM IS66 Orf2 family protein
MC63_RS24580	COG3547	Transposase (IS116 IS110 IS902 family)
MC63_RS24860	COG3344	reverse transcriptase