locus-tag	class	description
SA2016_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SA2016_RS00010	COG0592	DNA-directed DNA polymerase activity
SA2016_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SA2016_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SA2016_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SA2016_RS00030	COG0187	DNA topoisomerase II activity
SA2016_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SA2016_RS00055	COG2197	response regulator
SA2016_RS00140	COG1215	transferase activity, transferring glycosyl groups
SA2016_RS00155	COG0705	Rhomboid family
SA2016_RS00180	COG2814	Major facilitator Superfamily
SA2016_RS00190	COG1131	(ABC) transporter
SA2016_RS00210	COG0667	Aldo Keto reductase
SA2016_RS00215	COG2031	fatty acid transporter
SA2016_RS00220	COG0154	amidase activity
SA2016_RS00230	COG0436	Aminotransferase
SA2016_RS00235	COG1937	Protein conserved in bacteria
SA2016_RS00240	COG2130	NADP-dependent
SA2016_RS00245	COG0300	oxidoreductase activity
SA2016_RS00260	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS00270	COG2706	6-phosphogluconolactonase activity
SA2016_RS00300	COG0477	Major facilitator Superfamily
SA2016_RS00305	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SA2016_RS00310	COG0667	Aldo Keto reductase
SA2016_RS00340	COG1131	(ABC) transporter
SA2016_RS00360	COG2272	Belongs to the type-B carboxylesterase lipase family
SA2016_RS00365	COG2271	Major facilitator Superfamily
SA2016_RS00375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SA2016_RS00395	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS00410	COG2365	Tyrosine phosphatase family
SA2016_RS00415	COG1309	transcriptional regulator
SA2016_RS00435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SA2016_RS00445	COG4804	nuclease activity
SA2016_RS00460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SA2016_RS00465	COG3485	protocatechuate 3,4-dioxygenase
SA2016_RS00470	COG4638	Rieske (2fe-2S)
SA2016_RS00475	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
SA2016_RS00495	COG0583	DNA-binding transcription factor activity
SA2016_RS00500	COG4948	Mandelate Racemase Muconate Lactonizing
SA2016_RS00505	COG4829	muconolactone delta-isomerase
SA2016_RS00520	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS00525	COG2017	converts alpha-aldose to the beta-anomer
SA2016_RS00530	COG3387	PFAM Glycoside hydrolase 15-related
SA2016_RS00540	COG0667	Aldo Keto reductase
SA2016_RS00545	COG2409	Drug exporters of the RND superfamily
SA2016_RS00550	COG0702	epimerase
SA2016_RS00560	COG0142	geranyltranstransferase activity
SA2016_RS00590	COG0415	Belongs to the DNA photolyase family
SA2016_RS00605	COG0831	urea catabolic process
SA2016_RS00610	COG0832	Belongs to the urease beta subunit family
SA2016_RS00615	COG0804	urea catabolic process
SA2016_RS00620	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SA2016_RS00625	COG0830	nickel cation binding
SA2016_RS00630	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SA2016_RS00640	COG1234	tRNA 3'-trailer cleavage
SA2016_RS00660	COG1879	ABC-type sugar transport system periplasmic component
SA2016_RS00665	COG1129	ABC transporter
SA2016_RS00670	COG1172	Belongs to the binding-protein-dependent transport system permease family
SA2016_RS00690	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SA2016_RS00695	COG0022	dehydrogenase e1 component
SA2016_RS00710	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS00725	COG2195	Cleaves the N-terminal amino acid of tripeptides
SA2016_RS00735	COG1129	ABC transporter
SA2016_RS00740	COG1172	Belongs to the binding-protein-dependent transport system permease family
SA2016_RS00745	COG1879	ABC-type sugar transport system periplasmic component
SA2016_RS00750	COG0596	Alpha beta hydrolase
SA2016_RS00755	COG3246	L-lysine catabolic process to acetate
SA2016_RS00765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SA2016_RS00770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SA2016_RS00780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SA2016_RS00800	COG0277	FAD linked oxidase domain protein
SA2016_RS00805	COG3265	gluconokinase activity
SA2016_RS00810	COG2271	Major facilitator Superfamily
SA2016_RS00830	COG1072	(Pantothenic acid kinase))
SA2016_RS00835	COG1953	Uracil, thiamine, allantoin
SA2016_RS00850	COG1940	carbohydrate kinase activity
SA2016_RS00855	COG2182	Extracellular solute-binding protein
SA2016_RS00865	COG0395	ABC-type sugar transport system, permease component
SA2016_RS00870	COG3842	ATPase activity
SA2016_RS00880	COG1082	Xylose isomerase domain protein TIM barrel
SA2016_RS00885	COG0673	inositol 2-dehydrogenase activity
SA2016_RS00895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA2016_RS00920	COG1595	DNA-templated transcription, initiation
SA2016_RS00935	COG2271	Major facilitator Superfamily
SA2016_RS00960	COG1414	Transcriptional regulator
SA2016_RS00965	COG0135	phosphoribosylanthranilate isomerase activity
SA2016_RS00985	COG0438	transferase activity, transferring glycosyl groups
SA2016_RS01005	COG0515	serine threonine protein kinase
SA2016_RS01010	COG0768	penicillin binding
SA2016_RS01025	COG1716	ATPase activity
SA2016_RS01030	COG1716	ATPase activity
SA2016_RS01045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SA2016_RS01050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SA2016_RS01060	COG0477	Major facilitator Superfamily
SA2016_RS01070	COG3483	tryptophan 2,3-dioxygenase activity
SA2016_RS01135	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS01145	COG0783	Belongs to the Dps family
SA2016_RS01150	COG0385	Bile acid
SA2016_RS01165	COG2814	Major facilitator Superfamily
SA2016_RS01190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SA2016_RS01215	COG1929	Belongs to the glycerate kinase type-1 family
SA2016_RS01220	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SA2016_RS01225	COG2233	PERMEase
SA2016_RS01235	COG0778	Nitroreductase
SA2016_RS01290	COG1597	lipid kinase activity
SA2016_RS01295	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SA2016_RS01305	COG0561	phosphatase activity
SA2016_RS01320	COG2027	D-alanyl-D-alanine carboxypeptidase
SA2016_RS01330	COG0037	tRNA processing
SA2016_RS01340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SA2016_RS01345	COG0302	gtp cyclohydrolase
SA2016_RS01355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SA2016_RS01375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SA2016_RS01385	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SA2016_RS01405	COG2376	Dihydroxyacetone kinase
SA2016_RS01410	COG1461	Dihydroxyacetone kinase
SA2016_RS01415	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SA2016_RS01415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA2016_RS01415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SA2016_RS01420	COG1506	peptidase
SA2016_RS01420	COG0823	Involved in the tonB-independent uptake of proteins
SA2016_RS01425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SA2016_RS01440	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SA2016_RS01470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SA2016_RS01505	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SA2016_RS01570	COG0531	amino acid
SA2016_RS01575	COG1940	carbohydrate kinase activity
SA2016_RS01580	COG0363	glucosamine-6-phosphate deaminase activity
SA2016_RS01595	COG3360	Dodecin
SA2016_RS01600	COG2890	protein-(glutamine-N5) methyltransferase activity
SA2016_RS01615	COG2084	Dehydrogenase
SA2016_RS01630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SA2016_RS01640	COG0477	Major facilitator Superfamily
SA2016_RS01650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SA2016_RS01655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SA2016_RS01665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA2016_RS01670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SA2016_RS01675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA2016_RS01675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA2016_RS01675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA2016_RS01680	COG1105	Belongs to the carbohydrate kinase PfkB family
SA2016_RS01685	COG1349	DNA-binding transcription factor activity
SA2016_RS01700	COG2733	membrane
SA2016_RS01740	COG4122	O-methyltransferase activity
SA2016_RS01765	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS01780	COG2130	NADP-dependent
SA2016_RS01805	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SA2016_RS01810	COG2986	histidine ammonia-lyase
SA2016_RS01825	COG0038	chloride channel
SA2016_RS01835	COG2814	Major facilitator Superfamily
SA2016_RS01845	COG0010	Belongs to the arginase family
SA2016_RS01865	COG0431	NADPH-dependent FMN reductase
SA2016_RS01870	COG2252	PERMEase
SA2016_RS01925	COG1302	Protein conserved in bacteria
SA2016_RS01975	COG1609	Transcriptional regulator
SA2016_RS02010	COG4948	Mandelate Racemase Muconate Lactonizing
SA2016_RS02015	COG0800	Aldolase
SA2016_RS02035	COG0673	inositol 2-dehydrogenase activity
SA2016_RS02040	COG1609	Transcriptional regulator
SA2016_RS02050	COG1175	transmembrane transport
SA2016_RS02055	COG0395	ABC-type sugar transport system, permease component
SA2016_RS02065	COG1904	glucuronate isomerase
SA2016_RS02070	COG0246	Mannitol dehydrogenase
SA2016_RS02075	COG4948	Mandelate Racemase Muconate Lactonizing
SA2016_RS02080	COG3265	gluconokinase activity
SA2016_RS02105	COG0579	oxidoreductase
SA2016_RS02110	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SA2016_RS02130	COG3585	molybdate ion transport
SA2016_RS02180	COG0477	Major facilitator Superfamily
SA2016_RS02180	COG2814	Major facilitator Superfamily
SA2016_RS02195	COG2159	amidohydrolase
SA2016_RS02200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SA2016_RS02200	COG0357	Ribosomal RNA small subunit methyltransferase G
SA2016_RS02220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SA2016_RS02250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SA2016_RS02260	COG0366	Alpha amylase catalytic
SA2016_RS02265	COG1609	Transcriptional regulator
SA2016_RS02270	COG1653	transport
SA2016_RS02275	COG1175	transmembrane transport
SA2016_RS02280	COG0395	ABC-type sugar transport system, permease component
SA2016_RS02285	COG0673	inositol 2-dehydrogenase activity
SA2016_RS02305	COG2017	converts alpha-aldose to the beta-anomer
SA2016_RS02315	COG2115	Belongs to the xylose isomerase family
SA2016_RS02320	COG1070	Carbohydrate kinase
SA2016_RS02330	COG0277	FAD linked oxidase domain protein
SA2016_RS02340	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS02350	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS02360	COG0477	Major facilitator Superfamily
SA2016_RS02375	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SA2016_RS02390	COG1832	CoA-binding protein
SA2016_RS02395	COG2315	Protein conserved in bacteria
SA2016_RS02410	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS02415	COG1832	CoA-binding protein
SA2016_RS02430	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS02450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA2016_RS02500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SA2016_RS02505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SA2016_RS02510	COG0047	phosphoribosylformylglycinamidine synthase activity
SA2016_RS02520	COG3012	SEC-C Motif Domain Protein
SA2016_RS02525	COG1404	Belongs to the peptidase S8 family
SA2016_RS02540	COG1846	Transcriptional regulator
SA2016_RS02570	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SA2016_RS02600	COG0386	Belongs to the glutathione peroxidase family
SA2016_RS02620	COG1309	transcriptional regulator
SA2016_RS02630	COG0673	inositol 2-dehydrogenase activity
SA2016_RS02635	COG0673	inositol 2-dehydrogenase activity
SA2016_RS02645	COG0395	ABC-type sugar transport system, permease component
SA2016_RS02670	COG1940	carbohydrate kinase activity
SA2016_RS02725	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SA2016_RS02735	COG1396	sequence-specific DNA binding
SA2016_RS02760	COG2205	protein histidine kinase activity
SA2016_RS02765	COG0745	RESPONSE REGULATOR receiver
SA2016_RS02770	COG0477	Major facilitator Superfamily
SA2016_RS02775	COG2807	transmembrane transport
SA2016_RS02780	COG0343	queuine tRNA-ribosyltransferase activity
SA2016_RS02785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SA2016_RS02835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA2016_RS02840	COG3842	ATPase activity
SA2016_RS02865	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS02875	COG1280	lysine exporter protein (LysE YggA)
SA2016_RS02900	COG0564	pseudouridine synthase activity
SA2016_RS02905	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SA2016_RS02915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SA2016_RS02915	COG0574	Belongs to the PEP-utilizing enzyme family
SA2016_RS02950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SA2016_RS02955	COG1201	RNA secondary structure unwinding
SA2016_RS02965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SA2016_RS02970	COG0569	domain protein
SA2016_RS02970	COG0475	glutathione-regulated potassium exporter activity
SA2016_RS02985	COG0519	Catalyzes the synthesis of GMP from XMP
SA2016_RS02995	COG2169	Transcriptional regulator
SA2016_RS02995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SA2016_RS03000	COG1595	DNA-templated transcription, initiation
SA2016_RS03005	COG0590	tRNA wobble adenosine to inosine editing
SA2016_RS03010	COG0671	phosphoesterase, PA-phosphatase related
SA2016_RS03015	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SA2016_RS03040	COG1793	dna ligase
SA2016_RS03045	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SA2016_RS03045	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SA2016_RS03050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SA2016_RS03065	COG2205	protein histidine kinase activity
SA2016_RS03070	COG0745	RESPONSE REGULATOR receiver
SA2016_RS03090	COG2062	phosphohistidine phosphatase, SixA
SA2016_RS03100	COG1309	transcriptional regulator
SA2016_RS03105	COG1511	domain protein
SA2016_RS03140	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SA2016_RS03145	COG3848	Pyruvate phosphate dikinase
SA2016_RS03145	COG0574	Belongs to the PEP-utilizing enzyme family
SA2016_RS03150	COG0542	response to heat
SA2016_RS03155	COG0028	Belongs to the TPP enzyme family
SA2016_RS03160	COG1733	regulation of RNA biosynthetic process
SA2016_RS03165	COG2910	NAD(P)H-binding
SA2016_RS03170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SA2016_RS03170	COG1017	nitric oxide dioxygenase activity
SA2016_RS03175	COG1959	2 iron, 2 sulfur cluster binding
SA2016_RS03185	COG0697	spore germination
SA2016_RS03220	COG1505	serine-type exopeptidase activity
SA2016_RS03245	COG3321	synthase
SA2016_RS03245	COG0604	alcohol dehydrogenase
SA2016_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS03250	COG1966	Carbon starvation protein
SA2016_RS03270	COG0656	L-ascorbic acid biosynthetic process
SA2016_RS03280	COG0667	Aldo Keto reductase
SA2016_RS03300	COG0651	ATP synthesis coupled electron transport
SA2016_RS03305	COG1006	Multisubunit Na H antiporter MnhC subunit
SA2016_RS03335	COG2814	Major facilitator Superfamily
SA2016_RS03340	COG4948	Mandelate Racemase Muconate Lactonizing
SA2016_RS03345	COG0028	Belongs to the TPP enzyme family
SA2016_RS03400	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SA2016_RS03405	COG0859	PFAM glycosyl transferase family 9
SA2016_RS03415	COG0438	transferase activity, transferring glycosyl groups
SA2016_RS03420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SA2016_RS03450	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS03455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SA2016_RS03455	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SA2016_RS03460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SA2016_RS03460	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SA2016_RS03515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SA2016_RS03520	COG4786	Flagellar basal body rod
SA2016_RS03520	COG1256	bacterial-type flagellum assembly
SA2016_RS03530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SA2016_RS03560	COG1677	Flagellar hook-basal body complex protein FliE
SA2016_RS03565	COG1766	The M ring may be actively involved in energy transduction
SA2016_RS03570	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SA2016_RS03580	COG1157	protein secretion by the type III secretion system
SA2016_RS03600	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SA2016_RS03610	COG0688	phosphatidylethanolamine metabolic process
SA2016_RS03625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SA2016_RS03665	COG1338	Plays a role in the flagellum-specific transport system
SA2016_RS03680	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SA2016_RS03685	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SA2016_RS03695	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SA2016_RS03700	COG1191	sigma factor activity
SA2016_RS03710	COG0739	heme binding
SA2016_RS03710	COG1196	nuclear chromosome segregation
SA2016_RS03710	COG0741	lytic transglycosylase activity
SA2016_RS03715	COG0024	Methionine aminopeptidase
SA2016_RS03730	COG5002	protein histidine kinase activity
SA2016_RS03735	COG0745	RESPONSE REGULATOR receiver
SA2016_RS03745	COG2124	cytochrome p450
SA2016_RS03800	COG0546	phosphoglycolate phosphatase activity
SA2016_RS03815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SA2016_RS03820	COG0626	cystathionine gamma-synthase activity
SA2016_RS03835	COG0588	phosphoglycerate mutase activity
SA2016_RS03845	COG5002	protein histidine kinase activity
SA2016_RS03865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SA2016_RS03870	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SA2016_RS03880	COG0215	cysteine-tRNA ligase activity
SA2016_RS03915	COG0366	Alpha amylase catalytic
SA2016_RS03925	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SA2016_RS03960	COG3842	ATPase activity
SA2016_RS04025	COG3209	COG3209 Rhs family protein
SA2016_RS04035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SA2016_RS04040	COG0765	amino acid transport
SA2016_RS04045	COG1126	abc transporter atp-binding protein
SA2016_RS04050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SA2016_RS04075	COG0477	Major facilitator Superfamily
SA2016_RS04090	COG0477	Major facilitator Superfamily
SA2016_RS04120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SA2016_RS04220	COG0657	acetylesterase activity
SA2016_RS04285	COG1285	pathogenesis
SA2016_RS04295	COG0584	glycerophosphoryl diester phosphodiesterase
SA2016_RS04300	COG3842	ATPase activity
SA2016_RS04305	COG1177	transmembrane transport
SA2016_RS04320	COG1846	Transcriptional regulator
SA2016_RS04320	COG1940	carbohydrate kinase activity
SA2016_RS04335	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SA2016_RS04355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SA2016_RS04365	COG1349	DNA-binding transcription factor activity
SA2016_RS04370	COG1486	melibiose metabolic process
SA2016_RS04380	COG1175	transmembrane transport
SA2016_RS04385	COG0395	ABC-type sugar transport system, permease component
SA2016_RS04390	COG1653	transport
SA2016_RS04450	COG4948	Mandelate Racemase Muconate Lactonizing
SA2016_RS04455	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS04460	COG2814	Major facilitator Superfamily
SA2016_RS04495	COG3246	L-lysine catabolic process to acetate
SA2016_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS04520	COG5002	protein histidine kinase activity
SA2016_RS04540	COG0745	RESPONSE REGULATOR receiver
SA2016_RS04550	COG3547	Transposase (IS116 IS110 IS902 family)
SA2016_RS04660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SA2016_RS04665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SA2016_RS04705	COG0477	Major facilitator Superfamily
SA2016_RS04730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA2016_RS04735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SA2016_RS04740	COG1024	Enoyl-CoA hydratase
SA2016_RS04750	COG0673	inositol 2-dehydrogenase activity
SA2016_RS04755	COG1879	ABC-type sugar transport system periplasmic component
SA2016_RS04760	COG1129	ABC transporter
SA2016_RS04770	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS04785	COG4948	Mandelate Racemase Muconate Lactonizing
SA2016_RS04790	COG2271	Major facilitator Superfamily
SA2016_RS04795	COG2186	Transcriptional regulator
SA2016_RS04810	COG0531	amino acid
SA2016_RS04815	COG1940	carbohydrate kinase activity
SA2016_RS04820	COG0363	glucosamine-6-phosphate deaminase activity
SA2016_RS04830	COG1278	Cold shock
SA2016_RS04930	COG1215	transferase activity, transferring glycosyl groups
SA2016_RS04940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA2016_RS04960	COG1278	Cold shock
SA2016_RS04985	COG0464	growth
SA2016_RS05000	COG5479	isomerase activity
SA2016_RS05000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SA2016_RS05020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SA2016_RS05035	COG1177	transmembrane transport
SA2016_RS05040	COG3842	ATPase activity
SA2016_RS05060	COG4632	Exopolysaccharide biosynthesis protein
SA2016_RS05060	COG5434	Belongs to the glycosyl hydrolase 28 family
SA2016_RS05105	COG3511	phospholipase C
SA2016_RS05125	COG2116	formate transmembrane transporter activity
SA2016_RS05160	COG0477	Major facilitator Superfamily
SA2016_RS05170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SA2016_RS05180	COG1610	YqeY-like protein
SA2016_RS05185	COG0009	L-threonylcarbamoyladenylate synthase
SA2016_RS05230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SA2016_RS05230	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SA2016_RS05235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SA2016_RS05240	COG0509	glycine decarboxylation via glycine cleavage system
SA2016_RS05245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SA2016_RS05250	COG1760	l-serine dehydratase
SA2016_RS05255	COG0693	protein deglycase activity
SA2016_RS05275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SA2016_RS05295	COG0459	protein refolding
SA2016_RS05300	COG0328	RNA-DNA hybrid ribonuclease activity
SA2016_RS05310	COG2205	protein histidine kinase activity
SA2016_RS05315	COG0745	RESPONSE REGULATOR receiver
SA2016_RS05335	COG1278	Cold shock
SA2016_RS05355	COG0739	heme binding
SA2016_RS05375	COG0746	molybdenum cofactor guanylyltransferase activity
SA2016_RS05390	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SA2016_RS05410	COG1132	(ABC) transporter
SA2016_RS05450	COG0483	inositol monophosphate 1-phosphatase activity
SA2016_RS05475	COG1953	Uracil, thiamine, allantoin
SA2016_RS05480	COG0045	succinate-CoA ligase (ADP-forming) activity
SA2016_RS05490	COG2072	flavoprotein involved in K transport
SA2016_RS05505	COG0590	tRNA wobble adenosine to inosine editing
SA2016_RS05520	COG0477	Major facilitator Superfamily
SA2016_RS05545	COG0477	Major facilitator Superfamily
SA2016_RS05565	COG1414	Transcriptional regulator
SA2016_RS05575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SA2016_RS05615	COG2807	transmembrane transport
SA2016_RS05625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SA2016_RS05635	COG3962	Belongs to the TPP enzyme family
SA2016_RS05645	COG1082	Xylose isomerase domain protein TIM barrel
SA2016_RS05650	COG0673	inositol 2-dehydrogenase activity
SA2016_RS05655	COG1082	Xylose isomerase domain protein TIM barrel
SA2016_RS05670	COG3718	enzyme involved in inositol metabolism
SA2016_RS05675	COG2188	Transcriptional regulator
SA2016_RS05705	COG0531	amino acid
SA2016_RS05710	COG1609	Transcriptional regulator
SA2016_RS05715	COG0673	inositol 2-dehydrogenase activity
SA2016_RS05730	COG0477	Major facilitator Superfamily
SA2016_RS05735	COG1234	tRNA 3'-trailer cleavage
SA2016_RS05740	COG0583	DNA-binding transcription factor activity
SA2016_RS05750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SA2016_RS05755	COG0022	dehydrogenase e1 component
SA2016_RS05770	COG1396	sequence-specific DNA binding
SA2016_RS05790	COG0028	Belongs to the TPP enzyme family
SA2016_RS05795	COG1846	Transcriptional regulator
SA2016_RS05815	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS05825	COG1053	succinate dehydrogenase
SA2016_RS05830	COG0477	Major facilitator Superfamily
SA2016_RS05840	COG1053	succinate dehydrogenase
SA2016_RS05885	COG1401	restriction endodeoxyribonuclease activity
SA2016_RS05905	COG0589	response to stress
SA2016_RS05920	COG3559	Exporter of polyketide antibiotics
SA2016_RS05925	COG1131	(ABC) transporter
SA2016_RS05930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SA2016_RS05940	COG0363	glucosamine-6-phosphate deaminase activity
SA2016_RS05945	COG1263	PTS System
SA2016_RS05950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA2016_RS05955	COG2190	(PTS) system
SA2016_RS05955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA2016_RS05955	COG1263	PTS System
SA2016_RS05960	COG1609	Transcriptional regulator
SA2016_RS05965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SA2016_RS05975	COG2084	Dehydrogenase
SA2016_RS05985	COG0693	protein deglycase activity
SA2016_RS06010	COG1278	Cold shock
SA2016_RS06040	COG2271	Major facilitator Superfamily
SA2016_RS06060	COG0366	Alpha amylase catalytic
SA2016_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS06120	COG3795	YCII-related domain
SA2016_RS06125	COG4941	Belongs to the sigma-70 factor family
SA2016_RS06135	COG0531	amino acid
SA2016_RS06145	COG0583	DNA-binding transcription factor activity
SA2016_RS06150	COG2828	Protein conserved in bacteria
SA2016_RS06155	COG0477	Major facilitator Superfamily
SA2016_RS06160	COG1053	succinate dehydrogenase
SA2016_RS06220	COG3668	Plasmid stabilization system
SA2016_RS06235	COG2814	Major facilitator Superfamily
SA2016_RS06255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SA2016_RS06300	COG0596	Alpha beta hydrolase
SA2016_RS06310	COG0366	Alpha amylase catalytic
SA2016_RS06315	COG0395	ABC-type sugar transport system, permease component
SA2016_RS06320	COG1175	transmembrane transport
SA2016_RS06330	COG1609	Transcriptional regulator
SA2016_RS06335	COG0277	FAD linked oxidase domain protein
SA2016_RS06360	COG0726	polysaccharide deacetylase
SA2016_RS06405	COG0318	PFAM AMP-dependent synthetase and ligase
SA2016_RS06410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SA2016_RS06415	COG1609	Transcriptional regulator
SA2016_RS06420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SA2016_RS06465	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SA2016_RS06470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SA2016_RS06485	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS06490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SA2016_RS06500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SA2016_RS06520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SA2016_RS06525	COG0179	Fumarylacetoacetate (FAA) hydrolase
SA2016_RS06565	COG1063	alcohol dehydrogenase
SA2016_RS06575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SA2016_RS06585	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SA2016_RS06590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SA2016_RS06590	COG0438	transferase activity, transferring glycosyl groups
SA2016_RS06630	COG1063	alcohol dehydrogenase
SA2016_RS06635	COG0138	bifunctional purine biosynthesis protein purh
SA2016_RS06645	COG2838	Isocitrate dehydrogenase
SA2016_RS06680	COG4214	carbohydrate transport
SA2016_RS06685	COG1129	ABC transporter
SA2016_RS06705	COG2072	flavoprotein involved in K transport
SA2016_RS06710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SA2016_RS06715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SA2016_RS06720	COG4585	Histidine kinase
SA2016_RS06725	COG2197	response regulator
SA2016_RS06735	COG0477	Major facilitator Superfamily
SA2016_RS06740	COG0583	DNA-binding transcription factor activity
SA2016_RS06745	COG1131	(ABC) transporter
SA2016_RS06770	COG0180	Tryptophanyl-tRNA synthetase
SA2016_RS06780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SA2016_RS06795	COG2009	succinate dehydrogenase
SA2016_RS06805	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SA2016_RS06805	COG1473	amidohydrolase
SA2016_RS06810	COG1744	ABC transporter substrate-binding protein PnrA-like
SA2016_RS06815	COG3845	ABC transporter
SA2016_RS06820	COG4603	Belongs to the binding-protein-dependent transport system permease family
SA2016_RS06845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SA2016_RS06850	COG3956	TIGRFAM MazG family protein
SA2016_RS06855	COG0148	phosphopyruvate hydratase activity
SA2016_RS06910	COG0559	Belongs to the binding-protein-dependent transport system permease family
SA2016_RS06915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SA2016_RS06925	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SA2016_RS06935	COG1349	DNA-binding transcription factor activity
SA2016_RS06950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SA2016_RS06960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SA2016_RS06970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SA2016_RS06995	COG1331	Highly conserved protein containing a thioredoxin domain
SA2016_RS07005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SA2016_RS07015	COG1953	Uracil, thiamine, allantoin
SA2016_RS07025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SA2016_RS07045	COG0114	fumarate hydratase activity
SA2016_RS07050	COG0288	reversible hydration of carbon dioxide
SA2016_RS07060	COG1494	fructose-1,6-bisphosphatase
SA2016_RS07075	COG1316	TRANSCRIPTIONal
SA2016_RS07130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SA2016_RS07135	COG1376	ErfK ybiS ycfS ynhG family protein
SA2016_RS07175	COG0714	Associated with various cellular activities
SA2016_RS07180	COG0084	hydrolase, TatD family'
SA2016_RS07190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SA2016_RS07195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SA2016_RS07200	COG0488	(ABC) transporter
SA2016_RS07210	COG0586	Pfam SNARE associated Golgi protein
SA2016_RS07220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SA2016_RS07230	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SA2016_RS07235	COG0193	aminoacyl-tRNA hydrolase activity
SA2016_RS07255	COG0822	iron-sulfur transferase activity
SA2016_RS07270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SA2016_RS07275	COG0673	inositol 2-dehydrogenase activity
SA2016_RS07295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SA2016_RS07300	COG2244	polysaccharide biosynthetic process
SA2016_RS07310	COG1215	transferase activity, transferring glycosyl groups
SA2016_RS07360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SA2016_RS07395	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SA2016_RS07400	COG1609	Transcriptional regulator
SA2016_RS07415	COG1129	ABC transporter
SA2016_RS07420	COG1172	Belongs to the binding-protein-dependent transport system permease family
SA2016_RS07425	COG0673	inositol 2-dehydrogenase activity
SA2016_RS07430	COG1082	Xylose isomerase domain protein TIM barrel
SA2016_RS07455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SA2016_RS07455	COG1648	precorrin-2 dehydrogenase activity
SA2016_RS07460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SA2016_RS07470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SA2016_RS07485	COG3383	formate dehydrogenase (NAD+) activity
SA2016_RS07485	COG0243	molybdopterin cofactor binding
SA2016_RS07490	COG0243	molybdopterin cofactor binding
SA2016_RS07490	COG3383	formate dehydrogenase (NAD+) activity
SA2016_RS07495	COG0437	4 iron, 4 sulfur cluster binding
SA2016_RS07505	COG0709	Synthesizes selenophosphate from selenide and ATP
SA2016_RS07515	COG1921	L-seryl-tRNASec selenium transferase activity
SA2016_RS07530	COG3135	benzoate transporter
SA2016_RS07540	COG0243	molybdopterin cofactor binding
SA2016_RS07545	COG2223	nitrite transmembrane transporter activity
SA2016_RS07550	COG0477	Major facilitator Superfamily
SA2016_RS07555	COG4770	biotin carboxylase activity
SA2016_RS07560	COG0424	maF-like protein
SA2016_RS07565	COG2409	Drug exporters of the RND superfamily
SA2016_RS07575	COG1823	symporter activity
SA2016_RS07590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SA2016_RS07595	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS07615	COG0714	Associated with various cellular activities
SA2016_RS07635	COG0631	protein serine/threonine phosphatase activity
SA2016_RS07655	COG1674	ftsk spoiiie
SA2016_RS07670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SA2016_RS07675	COG0483	inositol monophosphate 1-phosphatase activity
SA2016_RS07685	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SA2016_RS07690	COG0154	amidase activity
SA2016_RS07695	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SA2016_RS07720	COG0583	DNA-binding transcription factor activity
SA2016_RS07725	COG1063	alcohol dehydrogenase
SA2016_RS07735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SA2016_RS07745	COG1228	amidohydrolase
SA2016_RS07760	COG5002	protein histidine kinase activity
SA2016_RS07765	COG0745	RESPONSE REGULATOR receiver
SA2016_RS07775	COG0671	phosphoesterase, PA-phosphatase related
SA2016_RS07790	COG2873	o-acetylhomoserine
SA2016_RS07795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SA2016_RS07830	COG2755	lipolytic protein G-D-S-L family
SA2016_RS07850	COG0423	glycine-tRNA ligase activity
SA2016_RS07880	COG0358	DNA primase activity
SA2016_RS07915	COG0438	transferase activity, transferring glycosyl groups
SA2016_RS07925	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS07935	COG0052	Belongs to the universal ribosomal protein uS2 family
SA2016_RS07940	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SA2016_RS07945	COG0528	UMP kinase activity
SA2016_RS07950	COG0233	cytoplasmic translational termination
SA2016_RS07965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SA2016_RS07975	COG3279	Response regulator of the LytR AlgR family
SA2016_RS07980	COG3275	phosphorelay sensor kinase activity
SA2016_RS07990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SA2016_RS08000	COG1522	sequence-specific DNA binding
SA2016_RS08010	COG0022	dehydrogenase e1 component
SA2016_RS08015	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS08020	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SA2016_RS08020	COG5479	isomerase activity
SA2016_RS08030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SA2016_RS08040	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS08070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SA2016_RS08075	COG0750	zinc metalloprotease
SA2016_RS08085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SA2016_RS08135	COG0442	prolyl-tRNA aminoacylation
SA2016_RS08160	COG0779	Required for maturation of 30S ribosomal subunits
SA2016_RS08175	COG0481	GTPase activity
SA2016_RS08175	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SA2016_RS08180	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SA2016_RS08185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SA2016_RS08205	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SA2016_RS08210	COG1185	polyribonucleotide nucleotidyltransferase activity
SA2016_RS08215	COG0612	Peptidase, M16
SA2016_RS08255	COG0315	cyclic pyranopterin monophosphate synthase activity
SA2016_RS08260	COG0315	cyclic pyranopterin monophosphate synthase activity
SA2016_RS08260	COG0521	Mo-molybdopterin cofactor biosynthetic process
SA2016_RS08270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SA2016_RS08295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SA2016_RS08305	COG1674	ftsk spoiiie
SA2016_RS08320	COG1396	sequence-specific DNA binding
SA2016_RS08335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SA2016_RS08340	COG2137	regulation of response to DNA damage stimulus
SA2016_RS08350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SA2016_RS08355	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SA2016_RS08360	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SA2016_RS08370	COG2813	Specifically methylates the guanine in position
SA2016_RS08375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SA2016_RS08385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SA2016_RS08395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SA2016_RS08400	COG0131	Imidazoleglycerol-phosphate dehydratase
SA2016_RS08405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SA2016_RS08410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SA2016_RS08430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SA2016_RS08435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SA2016_RS08440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SA2016_RS08455	COG2814	Major facilitator Superfamily
SA2016_RS08475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SA2016_RS08480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SA2016_RS08480	COG0072	phenylalanine-tRNA ligase activity
SA2016_RS08495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SA2016_RS08505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SA2016_RS08510	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SA2016_RS08515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SA2016_RS08520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SA2016_RS08525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SA2016_RS08530	COG1438	arginine binding
SA2016_RS08540	COG2318	DinB family
SA2016_RS08550	COG0110	maltose O-acetyltransferase activity
SA2016_RS08565	COG0137	argininosuccinate synthase activity
SA2016_RS08570	COG0165	Argininosuccinate lyase
SA2016_RS08585	COG2094	Belongs to the DNA glycosylase MPG family
SA2016_RS08590	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SA2016_RS08595	COG3973	AAA domain
SA2016_RS08600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SA2016_RS08625	COG0647	UMP catabolic process
SA2016_RS08635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SA2016_RS08640	COG0497	DNA recombination
SA2016_RS08645	COG0504	CTP synthase activity
SA2016_RS08650	COG0494	nUDIX hydrolase
SA2016_RS08670	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SA2016_RS08675	COG2079	MmgE PrpD family protein
SA2016_RS08700	COG1090	epimerase
SA2016_RS08715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SA2016_RS08720	COG1278	Cold shock
SA2016_RS08730	COG4565	transcriptional regulatory protein
SA2016_RS08735	COG3290	protein histidine kinase activity
SA2016_RS08740	COG1301	dicarboxylic acid transport
SA2016_RS08750	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SA2016_RS08755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SA2016_RS08770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SA2016_RS08775	COG1160	GTP binding
SA2016_RS08790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA2016_RS08800	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SA2016_RS08805	COG0509	glycine decarboxylation via glycine cleavage system
SA2016_RS08810	COG1716	ATPase activity
SA2016_RS08835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SA2016_RS08850	COG1940	carbohydrate kinase activity
SA2016_RS08870	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SA2016_RS08875	COG0515	serine threonine protein kinase
SA2016_RS08875	COG2815	serine threonine protein kinase
SA2016_RS08880	COG0741	lytic transglycosylase activity
SA2016_RS08890	COG0142	geranyltranstransferase activity
SA2016_RS08900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SA2016_RS08910	COG2001	Belongs to the MraZ family
SA2016_RS08915	COG0275	rRNA processing
SA2016_RS08930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SA2016_RS08935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SA2016_RS08940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SA2016_RS08945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SA2016_RS08955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SA2016_RS08960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SA2016_RS08965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SA2016_RS08970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SA2016_RS08975	COG1496	oxidoreductase activity
SA2016_RS08980	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SA2016_RS08985	COG1799	cell septum assembly
SA2016_RS09000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SA2016_RS09010	COG0587	DNA-directed DNA polymerase activity
SA2016_RS09020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SA2016_RS09025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SA2016_RS09045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SA2016_RS09055	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SA2016_RS09080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SA2016_RS09085	COG0321	lipoyl(octanoyl) transferase activity
SA2016_RS09100	COG1764	response to oxidative stress
SA2016_RS09110	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS09115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SA2016_RS09120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SA2016_RS09140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SA2016_RS09150	COG0187	DNA topoisomerase II activity
SA2016_RS09165	COG1271	oxidase subunit
SA2016_RS09170	COG1294	oxidase, subunit
SA2016_RS09175	COG4988	ABC transporter
SA2016_RS09190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SA2016_RS09210	COG1435	thymidine kinase activity
SA2016_RS09230	COG0756	dUTP diphosphatase activity
SA2016_RS09260	COG0569	domain protein
SA2016_RS09265	COG0531	amino acid
SA2016_RS09270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SA2016_RS09275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SA2016_RS09280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SA2016_RS09295	COG0667	Aldo Keto reductase
SA2016_RS09320	COG1122	ATPase activity
SA2016_RS09330	COG1024	Enoyl-CoA hydratase
SA2016_RS09330	COG1250	3-hydroxyacyl-CoA dehydrogenase
SA2016_RS09335	COG0183	Belongs to the thiolase family
SA2016_RS09340	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SA2016_RS09365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SA2016_RS09380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SA2016_RS09445	COG0242	peptide deformylase activity
SA2016_RS09450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SA2016_RS09460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SA2016_RS09480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SA2016_RS09480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SA2016_RS09485	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SA2016_RS09490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SA2016_RS09495	COG0140	phosphoribosyl-ATP diphosphatase activity
SA2016_RS09500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SA2016_RS09505	COG0107	imidazoleglycerol-phosphate synthase activity
SA2016_RS09520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SA2016_RS09540	COG0134	indole-3-glycerol-phosphate synthase activity
SA2016_RS09545	COG0133	tryptophan synthase activity
SA2016_RS09550	COG0159	tryptophan synthase activity
SA2016_RS09555	COG0070	glutamate synthase
SA2016_RS09555	COG0069	glutamate synthase activity
SA2016_RS09555	COG0067	glutamate synthase
SA2016_RS09565	COG0469	pyruvate kinase activity
SA2016_RS09595	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SA2016_RS09600	COG2050	protein possibly involved in aromatic compounds catabolism
SA2016_RS09610	COG4552	Acetyltransferase involved in intracellular survival and related
SA2016_RS09620	COG0539	negative regulation of cytoplasmic translation
SA2016_RS09625	COG1739	Uncharacterized protein family UPF0029
SA2016_RS09630	COG0237	dephospho-CoA kinase activity
SA2016_RS09635	COG0556	nucleotide-excision repair
SA2016_RS09665	COG4106	trans-aconitate 2-methyltransferase activity
SA2016_RS09690	COG0546	phosphoglycolate phosphatase activity
SA2016_RS09700	COG0322	excinuclease ABC activity
SA2016_RS09705	COG1660	Displays ATPase and GTPase activities
SA2016_RS09715	COG1481	regulation of sporulation
SA2016_RS09720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SA2016_RS09725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SA2016_RS09730	COG0126	phosphoglycerate kinase activity
SA2016_RS09735	COG0149	triose-phosphate isomerase activity
SA2016_RS09740	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SA2016_RS09745	COG0363	glucosamine-6-phosphate deaminase activity
SA2016_RS09760	COG0166	Belongs to the GPI family
SA2016_RS09765	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SA2016_RS09775	COG0109	protoheme IX farnesyltransferase activity
SA2016_RS09780	COG1612	heme a metabolic process
SA2016_RS09805	COG0719	Fe-S assembly protein
SA2016_RS09810	COG0396	ATPase activity
SA2016_RS09815	COG2151	metal-sulfur cluster biosynthetic enzyme
SA2016_RS09825	COG0318	PFAM AMP-dependent synthetase and ligase
SA2016_RS09830	COG0183	Belongs to the thiolase family
SA2016_RS09840	COG1122	ATPase activity
SA2016_RS09845	COG1268	BioY protein
SA2016_RS09855	COG0514	ATP-dependent DNA helicase (RecQ)
SA2016_RS09860	COG0243	molybdopterin cofactor binding
SA2016_RS09860	COG3383	formate dehydrogenase (NAD+) activity
SA2016_RS09865	COG0437	4 iron, 4 sulfur cluster binding
SA2016_RS09875	COG0488	(ABC) transporter
SA2016_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS09905	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS09910	COG0560	Phosphoserine phosphatase
SA2016_RS09910	COG3830	Belongs to the UPF0237 family
SA2016_RS09915	COG1119	ATPase activity
SA2016_RS09930	COG0254	rRNA binding
SA2016_RS09955	COG1305	Transglutaminase-like
SA2016_RS09970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SA2016_RS09975	COG0297	glycogen (starch) synthase activity
SA2016_RS10000	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS10025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SA2016_RS10040	COG1215	transferase activity, transferring glycosyl groups
SA2016_RS10045	COG3979	chitinase
SA2016_RS10070	COG1968	undecaprenyl-diphosphatase activity
SA2016_RS10075	COG0215	cysteine-tRNA ligase activity
SA2016_RS10085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SA2016_RS10090	COG0517	IMP dehydrogenase activity
SA2016_RS10090	COG1994	Peptidase M50
SA2016_RS10100	COG1222	aaa ATPase
SA2016_RS10105	COG4122	O-methyltransferase activity
SA2016_RS10115	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SA2016_RS10120	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SA2016_RS10125	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SA2016_RS10130	COG0545	Peptidyl-prolyl cis-trans isomerase
SA2016_RS10150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SA2016_RS10155	COG0805	protein transport
SA2016_RS10165	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SA2016_RS10170	COG1216	Glycosyl transferase, family 2
SA2016_RS10190	COG2186	Transcriptional regulator
SA2016_RS10195	COG2364	Membrane
SA2016_RS10205	COG4946	Tricorn protease homolog
SA2016_RS10205	COG1506	peptidase
SA2016_RS10205	COG0823	Involved in the tonB-independent uptake of proteins
SA2016_RS10210	COG0242	peptide deformylase activity
SA2016_RS10220	COG0583	DNA-binding transcription factor activity
SA2016_RS10235	COG0697	spore germination
SA2016_RS10240	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SA2016_RS10240	COG1796	DNA polymerase
SA2016_RS10245	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS10250	COG1316	TRANSCRIPTIONal
SA2016_RS10255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SA2016_RS10265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SA2016_RS10270	COG4941	Belongs to the sigma-70 factor family
SA2016_RS10295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SA2016_RS10300	COG1845	cytochrome c oxidase, subunit III
SA2016_RS10305	COG2010	Cytochrome c
SA2016_RS10310	COG0723	plastoquinol--plastocyanin reductase activity
SA2016_RS10315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SA2016_RS10320	COG2188	Transcriptional regulator
SA2016_RS10330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SA2016_RS10335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SA2016_RS10355	COG0167	dihydroorotate dehydrogenase activity
SA2016_RS10365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SA2016_RS10370	COG1381	Involved in DNA repair and RecF pathway recombination
SA2016_RS10375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SA2016_RS10380	COG3590	peptidase
SA2016_RS10385	COG1316	TRANSCRIPTIONal
SA2016_RS10390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SA2016_RS10400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SA2016_RS10420	COG0484	heat shock protein binding
SA2016_RS10425	COG1420	regulation of RNA biosynthetic process
SA2016_RS10445	COG0481	GTPase activity
SA2016_RS10450	COG0268	Binds directly to 16S ribosomal RNA
SA2016_RS10460	COG1063	alcohol dehydrogenase
SA2016_RS10465	COG0436	Aminotransferase
SA2016_RS10470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SA2016_RS10485	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SA2016_RS10490	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SA2016_RS10495	COG1984	allophanate hydrolase subunit 2
SA2016_RS10500	COG4221	oxidoreductase activity
SA2016_RS10510	COG3265	gluconokinase activity
SA2016_RS10515	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS10530	COG4221	oxidoreductase activity
SA2016_RS10555	COG1307	EDD domain protein, DegV family
SA2016_RS10560	COG0495	leucyl-tRNA aminoacylation
SA2016_RS10565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SA2016_RS10570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SA2016_RS10575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SA2016_RS10595	COG0297	glycogen (starch) synthase activity
SA2016_RS10605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SA2016_RS10615	COG1758	RNA polymerase activity
SA2016_RS10620	COG0194	GDP metabolic process
SA2016_RS10625	COG0194	GDP metabolic process
SA2016_RS10630	COG0284	orotidine-5'-phosphate decarboxylase activity
SA2016_RS10635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SA2016_RS10640	COG0505	Belongs to the CarA family
SA2016_RS10650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SA2016_RS10655	COG0540	Belongs to the ATCase OTCase family
SA2016_RS10660	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SA2016_RS10665	COG2339	peptidase activity
SA2016_RS10670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SA2016_RS10675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SA2016_RS10685	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SA2016_RS10695	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SA2016_RS10700	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SA2016_RS10710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SA2016_RS10715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SA2016_RS10730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SA2016_RS10745	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SA2016_RS10750	COG0124	histidyl-tRNA synthetase
SA2016_RS10760	COG1196	nuclear chromosome segregation
SA2016_RS10770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SA2016_RS10775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SA2016_RS10780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SA2016_RS10790	COG2255	four-way junction helicase activity
SA2016_RS10795	COG0632	four-way junction helicase activity
SA2016_RS10800	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SA2016_RS10805	COG0217	transcriptional regulatory protein
SA2016_RS10810	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SA2016_RS10815	COG0367	asparagine synthase
SA2016_RS10835	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS10840	COG0022	dehydrogenase e1 component
SA2016_RS10840	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS10845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SA2016_RS10850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA2016_RS10855	COG2186	Transcriptional regulator
SA2016_RS10860	COG2721	sulfolactate sulfo-lyase activity
SA2016_RS10865	COG2721	sulfolactate sulfo-lyase activity
SA2016_RS10870	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS10880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SA2016_RS10885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SA2016_RS10890	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SA2016_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS10910	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SA2016_RS10915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SA2016_RS10925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SA2016_RS10930	COG2135	peptidase activity
SA2016_RS10970	COG0477	Major facilitator Superfamily
SA2016_RS10995	COG0726	polysaccharide deacetylase
SA2016_RS11000	COG0477	Major facilitator Superfamily
SA2016_RS11005	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS11020	COG0667	Aldo Keto reductase
SA2016_RS11025	COG0588	phosphoglycerate mutase activity
SA2016_RS11030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SA2016_RS11095	COG0673	inositol 2-dehydrogenase activity
SA2016_RS11105	COG1609	Transcriptional regulator
SA2016_RS11115	COG0800	Aldolase
SA2016_RS11140	COG0318	PFAM AMP-dependent synthetase and ligase
SA2016_RS11145	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS11150	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SA2016_RS11160	COG0183	Belongs to the thiolase family
SA2016_RS11175	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SA2016_RS11180	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS11185	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS11215	COG0667	Aldo Keto reductase
SA2016_RS11280	COG2186	Transcriptional regulator
SA2016_RS11285	COG1850	ribulose-bisphosphate carboxylase activity
SA2016_RS11295	COG1063	alcohol dehydrogenase
SA2016_RS11330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SA2016_RS11335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SA2016_RS11340	COG1780	Probably involved in ribonucleotide reductase function
SA2016_RS11345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SA2016_RS11350	COG0583	DNA-binding transcription factor activity
SA2016_RS11360	COG2801	Transposase and inactivated derivatives
SA2016_RS11360	COG3415	Transposase
SA2016_RS11370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SA2016_RS11405	COG0714	Associated with various cellular activities
SA2016_RS11455	COG1584	GPR1 FUN34 yaaH family protein
SA2016_RS11460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA2016_RS11475	COG0406	alpha-ribazole phosphatase activity
SA2016_RS11480	COG0799	negative regulation of ribosome biogenesis
SA2016_RS11490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SA2016_RS11500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SA2016_RS11505	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SA2016_RS11510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SA2016_RS11515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SA2016_RS11520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SA2016_RS11525	COG0351	phosphomethylpyrimidine kinase
SA2016_RS11525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SA2016_RS11525	COG0352	thiamine-phosphate diphosphorylase activity
SA2016_RS11540	COG0105	UTP biosynthetic process
SA2016_RS11550	COG0285	dihydrofolate synthase activity
SA2016_RS11555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SA2016_RS11565	COG3189	MarR family transcriptional regulator
SA2016_RS11570	COG0525	valine-tRNA ligase activity
SA2016_RS11575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SA2016_RS11580	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SA2016_RS11585	COG0740	serine-type endopeptidase activity
SA2016_RS11590	COG0740	serine-type endopeptidase activity
SA2016_RS11595	COG0544	peptidyl-prolyl cis-trans isomerase activity
SA2016_RS11635	COG0668	transmembrane transport
SA2016_RS11650	COG0824	Thioesterase
SA2016_RS11665	COG0629	single-stranded DNA binding
SA2016_RS11705	COG0242	peptide deformylase activity
SA2016_RS11725	COG3022	response to hydroperoxide
SA2016_RS11735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SA2016_RS11740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SA2016_RS11750	COG1045	serine acetyltransferase
SA2016_RS11760	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SA2016_RS11780	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SA2016_RS11795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SA2016_RS11800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SA2016_RS11815	COG4974	Belongs to the 'phage' integrase family
SA2016_RS11830	COG0792	nuclease activity
SA2016_RS11840	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SA2016_RS11850	COG0681	Belongs to the peptidase S26 family
SA2016_RS11855	COG0335	large ribosomal subunit rRNA binding
SA2016_RS11860	COG0336	Belongs to the RNA methyltransferase TrmD family
SA2016_RS11865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SA2016_RS11870	COG1837	Belongs to the UPF0109 family
SA2016_RS11875	COG0228	four-way junction DNA binding
SA2016_RS11885	COG2514	catechol 2,3-dioxygenase activity
SA2016_RS11895	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SA2016_RS11905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SA2016_RS11945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SA2016_RS11950	COG0571	ribonuclease III activity
SA2016_RS11955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SA2016_RS11965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SA2016_RS11975	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SA2016_RS11990	COG0742	ribosomal rna small subunit methyltransferase
SA2016_RS12000	COG1461	Dihydroxyacetone kinase
SA2016_RS12015	COG1181	Belongs to the D-alanine--D-alanine ligase family
SA2016_RS12020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SA2016_RS12030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SA2016_RS12035	COG0066	3-isopropylmalate dehydratase activity
SA2016_RS12040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SA2016_RS12045	COG1414	Transcriptional regulator
SA2016_RS12075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SA2016_RS12080	COG0179	Fumarylacetoacetate (FAA) hydrolase
SA2016_RS12085	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SA2016_RS12090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SA2016_RS12095	COG0473	3-isopropylmalate dehydrogenase activity
SA2016_RS12125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SA2016_RS12130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SA2016_RS12135	COG0440	acetolactate synthase activity
SA2016_RS12150	COG0129	dihydroxy-acid dehydratase activity
SA2016_RS12155	COG0583	DNA-binding transcription factor activity
SA2016_RS12180	COG3118	belongs to the thioredoxin family
SA2016_RS12200	COG0747	negative chemotaxis
SA2016_RS12205	COG0579	oxidoreductase
SA2016_RS12210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SA2016_RS12225	COG1305	Transglutaminase-like
SA2016_RS12240	COG2186	Transcriptional regulator
SA2016_RS12250	COG1027	Aspartate ammonia-lyase
SA2016_RS12270	COG1104	cysteine desulfurase activity
SA2016_RS12280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SA2016_RS12285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SA2016_RS12300	COG1113	amino acid transport
SA2016_RS12310	COG0022	dehydrogenase e1 component
SA2016_RS12315	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS12325	COG0179	Fumarylacetoacetate (FAA) hydrolase
SA2016_RS12335	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS12345	COG3971	2-oxopent-4-enoate hydratase activity
SA2016_RS12370	COG3226	Transcriptional regulator
SA2016_RS12380	COG2267	carboxylic ester hydrolase activity
SA2016_RS12405	COG0419	ATPase involved in DNA repair
SA2016_RS12410	COG0420	3'-5' exonuclease activity
SA2016_RS12425	COG0038	chloride channel
SA2016_RS12450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SA2016_RS12455	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SA2016_RS12460	COG0656	L-ascorbic acid biosynthetic process
SA2016_RS12470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SA2016_RS12480	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SA2016_RS12515	COG0363	glucosamine-6-phosphate deaminase activity
SA2016_RS12545	COG0628	permease
SA2016_RS12560	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SA2016_RS12565	COG0402	S-adenosylhomocysteine deaminase activity
SA2016_RS12575	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SA2016_RS12585	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SA2016_RS12590	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SA2016_RS12595	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SA2016_RS12600	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SA2016_RS12605	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SA2016_RS12610	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SA2016_RS12615	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SA2016_RS12620	COG0356	it plays a direct role in the translocation of protons across the membrane
SA2016_RS12640	COG1086	Polysaccharide biosynthesis protein
SA2016_RS12655	COG2890	protein-(glutamine-N5) methyltransferase activity
SA2016_RS12660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SA2016_RS12670	COG0083	homoserine kinase activity
SA2016_RS12675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SA2016_RS12680	COG0460	homoserine dehydrogenase
SA2016_RS12690	COG0018	arginyl-trna synthetase
SA2016_RS12710	COG1643	Atp-dependent helicase
SA2016_RS12720	COG1064	alcohol dehydrogenase
SA2016_RS12745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SA2016_RS12750	COG1121	(ABC) transporter
SA2016_RS12760	COG1253	flavin adenine dinucleotide binding
SA2016_RS12765	COG1253	flavin adenine dinucleotide binding
SA2016_RS12770	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS12770	COG0567	Dehydrogenase, E1 component
SA2016_RS12785	COG1595	DNA-templated transcription, initiation
SA2016_RS12795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SA2016_RS12805	COG0483	inositol monophosphate 1-phosphatase activity
SA2016_RS12835	COG0477	Major facilitator Superfamily
SA2016_RS12845	COG1472	Belongs to the glycosyl hydrolase 3 family
SA2016_RS12850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SA2016_RS12860	COG2177	Part of the ABC transporter FtsEX involved in
SA2016_RS12865	COG2884	Cell division ATP-binding protein ftsE
SA2016_RS12910	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SA2016_RS12915	COG1876	peptidase activity
SA2016_RS12965	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SA2016_RS12975	COG1216	Glycosyl transferase, family 2
SA2016_RS13010	COG0463	Glycosyl transferase, family 2
SA2016_RS13050	COG1216	Glycosyl transferase, family 2
SA2016_RS13080	COG2902	Dehydrogenase
SA2016_RS13115	COG0653	protein targeting
SA2016_RS13120	COG3214	Protein conserved in bacteria
SA2016_RS13125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SA2016_RS13135	COG5401	PFAM Sporulation and spore germination
SA2016_RS13140	COG5002	protein histidine kinase activity
SA2016_RS13140	COG5000	phosphorelay sensor kinase activity
SA2016_RS13145	COG0745	RESPONSE REGULATOR receiver
SA2016_RS13175	COG0601	transmembrane transport
SA2016_RS13190	COG0482	sulfurtransferase activity
SA2016_RS13220	COG0484	heat shock protein binding
SA2016_RS13225	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SA2016_RS13230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SA2016_RS13235	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SA2016_RS13240	COG2086	electron transfer activity
SA2016_RS13245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SA2016_RS13255	COG1842	Phage shock protein A
SA2016_RS13265	COG1615	UPF0182 protein
SA2016_RS13270	COG3480	Lon protease (S16) C-terminal proteolytic domain
SA2016_RS13325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SA2016_RS13330	COG0765	amino acid transport
SA2016_RS13335	COG1126	abc transporter atp-binding protein
SA2016_RS13340	COG1522	sequence-specific DNA binding
SA2016_RS13345	COG1280	lysine exporter protein (LysE YggA)
SA2016_RS13350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SA2016_RS13360	COG0113	porphobilinogen synthase activity
SA2016_RS13370	COG0181	hydroxymethylbilane synthase activity
SA2016_RS13375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SA2016_RS13380	COG3253	May function as heme-dependent peroxidase
SA2016_RS13390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SA2016_RS13395	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SA2016_RS13405	COG1309	transcriptional regulator
SA2016_RS13430	COG2154	pterin-4-alpha-carbinolamine dehydratase
SA2016_RS13435	COG2022	thiamine diphosphate biosynthetic process
SA2016_RS13445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SA2016_RS13445	COG2022	thiamine diphosphate biosynthetic process
SA2016_RS13450	COG0352	thiamine-phosphate diphosphorylase activity
SA2016_RS13455	COG1605	Chorismate mutase
SA2016_RS13455	COG0077	Prephenate dehydratase
SA2016_RS13475	COG2189	Belongs to the N(4) N(6)-methyltransferase family
SA2016_RS13480	COG0613	PHP domain protein
SA2016_RS13485	COG0006	proline dipeptidase activity
SA2016_RS13495	COG2239	Acts as a magnesium transporter
SA2016_RS13510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SA2016_RS13520	COG1595	DNA-templated transcription, initiation
SA2016_RS13545	COG1126	abc transporter atp-binding protein
SA2016_RS13550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SA2016_RS13555	COG0765	amino acid transport
SA2016_RS13560	COG0765	amino acid transport
SA2016_RS13565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SA2016_RS13570	COG2171	N-acyltransferase activity
SA2016_RS13585	COG3226	Transcriptional regulator
SA2016_RS13645	COG1217	gtp-binding protein TYPA
SA2016_RS13665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA2016_RS13675	COG4166	transmembrane transport
SA2016_RS13695	COG3511	phospholipase C
SA2016_RS13700	COG0012	GTP binding
SA2016_RS13705	COG1322	Protein conserved in bacteria
SA2016_RS13710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SA2016_RS13720	COG1570	exodeoxyribonuclease VII activity
SA2016_RS13725	COG1722	exodeoxyribonuclease VII activity
SA2016_RS13730	COG2326	polyphosphate kinase activity
SA2016_RS13735	COG0436	Aminotransferase
SA2016_RS13750	COG1174	glycine betaine transport
SA2016_RS13755	COG0517	IMP dehydrogenase activity
SA2016_RS13755	COG1125	glycine betaine transport
SA2016_RS13775	COG0583	DNA-binding transcription factor activity
SA2016_RS13780	COG2814	Major facilitator Superfamily
SA2016_RS13785	COG1522	sequence-specific DNA binding
SA2016_RS13810	COG0598	Magnesium transport protein CorA
SA2016_RS13820	COG0039	L-malate dehydrogenase activity
SA2016_RS13850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SA2016_RS13875	COG0519	Catalyzes the synthesis of GMP from XMP
SA2016_RS13875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SA2016_RS13895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SA2016_RS13900	COG0516	GMP reductase activity
SA2016_RS13920	COG0459	protein refolding
SA2016_RS13925	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SA2016_RS13940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SA2016_RS13945	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SA2016_RS13950	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS13955	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SA2016_RS13965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SA2016_RS13980	COG0802	atpase or kinase
SA2016_RS13985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SA2016_RS13990	COG0438	transferase activity, transferring glycosyl groups
SA2016_RS13995	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SA2016_RS14010	COG1260	myo-inositol-1-phosphate synthase
SA2016_RS14020	COG1597	lipid kinase activity
SA2016_RS14025	COG2261	transglycosylase associated protein
SA2016_RS14040	COG0484	heat shock protein binding
SA2016_RS14050	COG0473	3-isopropylmalate dehydrogenase activity
SA2016_RS14055	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
SA2016_RS14090	COG1846	Transcriptional regulator
SA2016_RS14110	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SA2016_RS14130	COG2267	carboxylic ester hydrolase activity
SA2016_RS14135	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SA2016_RS14145	COG3848	Pyruvate phosphate dikinase
SA2016_RS14145	COG0574	Belongs to the PEP-utilizing enzyme family
SA2016_RS14185	COG1609	Transcriptional regulator
SA2016_RS14200	COG0395	ABC-type sugar transport system, permease component
SA2016_RS14210	COG1621	beta-fructofuranosidase activity
SA2016_RS14220	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS14240	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS14270	COG1309	transcriptional regulator
SA2016_RS14280	COG0515	serine threonine protein kinase
SA2016_RS14280	COG2815	serine threonine protein kinase
SA2016_RS14315	COG0297	glycogen (starch) synthase activity
SA2016_RS14325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SA2016_RS14330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SA2016_RS14335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SA2016_RS14400	COG1191	sigma factor activity
SA2016_RS14405	COG1309	transcriptional regulator
SA2016_RS14450	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SA2016_RS14450	COG5479	isomerase activity
SA2016_RS14455	COG2201	protein-glutamate methylesterase activity
SA2016_RS14490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SA2016_RS14495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SA2016_RS14505	COG0730	response to heat
SA2016_RS14515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SA2016_RS14520	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SA2016_RS14525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SA2016_RS14525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA2016_RS14535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SA2016_RS14540	COG1191	sigma factor activity
SA2016_RS14570	COG0659	secondary active sulfate transmembrane transporter activity
SA2016_RS14575	COG0736	holo-[acyl-carrier-protein] synthase activity
SA2016_RS14600	COG0463	Glycosyl transferase, family 2
SA2016_RS14620	COG0726	polysaccharide deacetylase
SA2016_RS14630	COG1072	(Pantothenic acid kinase))
SA2016_RS14635	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SA2016_RS14645	COG1970	mechanosensitive ion channel activity
SA2016_RS14655	COG2318	DinB family
SA2016_RS14660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SA2016_RS14670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SA2016_RS14675	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SA2016_RS14680	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SA2016_RS14735	COG0101	tRNA pseudouridine synthase activity
SA2016_RS14795	COG0745	RESPONSE REGULATOR receiver
SA2016_RS14800	COG5002	protein histidine kinase activity
SA2016_RS14805	COG0203	ribosomal protein L17
SA2016_RS14810	COG0202	RNA polymerase activity
SA2016_RS14815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SA2016_RS14820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SA2016_RS14825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SA2016_RS14830	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SA2016_RS14845	COG3191	aminopeptidase activity
SA2016_RS14870	COG0024	Methionine aminopeptidase
SA2016_RS14875	COG0563	adenylate kinase activity
SA2016_RS14885	COG0200	Binds to the 23S rRNA
SA2016_RS14890	COG1841	ribosomal large subunit assembly
SA2016_RS14895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SA2016_RS14900	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SA2016_RS14905	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SA2016_RS14910	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SA2016_RS14915	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SA2016_RS14920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SA2016_RS14925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SA2016_RS14935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SA2016_RS14940	COG0255	Belongs to the universal ribosomal protein uL29 family
SA2016_RS14945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SA2016_RS14950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SA2016_RS14955	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SA2016_RS14960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SA2016_RS14965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SA2016_RS14970	COG0089	rRNA binding
SA2016_RS14975	COG0088	Forms part of the polypeptide exit tunnel
SA2016_RS14980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SA2016_RS14985	COG0051	transcription antitermination factor activity, RNA binding
SA2016_RS15000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SA2016_RS15005	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SA2016_RS15010	COG0049	tRNA binding
SA2016_RS15015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SA2016_RS15020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SA2016_RS15025	COG0085	RNA polymerase activity
SA2016_RS15030	COG0183	Belongs to the thiolase family
SA2016_RS15035	COG0442	prolyl-tRNA aminoacylation
SA2016_RS15040	COG0222	ribosome binding
SA2016_RS15045	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SA2016_RS15050	COG1793	dna ligase
SA2016_RS15065	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SA2016_RS15070	COG1140	nitrate reductase beta subunit
SA2016_RS15090	COG0081	regulation of translation
SA2016_RS15095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SA2016_RS15105	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SA2016_RS15115	COG0436	Aminotransferase
SA2016_RS15120	COG2197	response regulator
SA2016_RS15180	COG0354	folic acid binding
SA2016_RS15185	COG3485	protocatechuate 3,4-dioxygenase
SA2016_RS15195	COG0745	RESPONSE REGULATOR receiver
SA2016_RS15200	COG0456	acetyltransferase
SA2016_RS15210	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SA2016_RS15220	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SA2016_RS15250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SA2016_RS15265	COG0183	Belongs to the thiolase family
SA2016_RS15270	COG0318	PFAM AMP-dependent synthetase and ligase
SA2016_RS15275	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS15280	COG1250	3-hydroxyacyl-CoA dehydrogenase
SA2016_RS15280	COG1024	Enoyl-CoA hydratase
SA2016_RS15290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SA2016_RS15295	COG0738	Major facilitator superfamily
SA2016_RS15305	COG2030	dehydratase
SA2016_RS15315	COG0659	secondary active sulfate transmembrane transporter activity
SA2016_RS15335	COG0366	Alpha amylase catalytic
SA2016_RS15340	COG1940	carbohydrate kinase activity
SA2016_RS15345	COG2755	lipolytic protein G-D-S-L family
SA2016_RS15345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SA2016_RS15405	COG0587	DNA-directed DNA polymerase activity
SA2016_RS15440	COG0318	PFAM AMP-dependent synthetase and ligase
SA2016_RS15450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SA2016_RS15455	COG2814	Major facilitator Superfamily
SA2016_RS15485	COG1666	GTP binding
SA2016_RS15495	COG2233	PERMEase
SA2016_RS15500	COG0590	tRNA wobble adenosine to inosine editing
SA2016_RS15505	COG3608	succinylglutamate desuccinylase aspartoacylase
SA2016_RS15505	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SA2016_RS15515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SA2016_RS15515	COG2080	2 iron, 2 sulfur cluster binding
SA2016_RS15530	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SA2016_RS15535	COG0501	Belongs to the peptidase M48B family
SA2016_RS15545	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS15545	COG0596	Alpha beta hydrolase
SA2016_RS15565	COG0531	amino acid
SA2016_RS15595	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SA2016_RS15595	COG2508	Transcriptional regulator
SA2016_RS15605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SA2016_RS15605	COG1648	precorrin-2 dehydrogenase activity
SA2016_RS15610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SA2016_RS15615	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SA2016_RS15635	COG2895	sulfate adenylyltransferase (ATP) activity
SA2016_RS15645	COG0175	sulfate reduction
SA2016_RS15650	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SA2016_RS15675	COG0142	geranyltranstransferase activity
SA2016_RS15685	COG2226	methyltransferase
SA2016_RS15690	COG1063	alcohol dehydrogenase
SA2016_RS15695	COG1169	isochorismate synthase
SA2016_RS15700	COG1126	abc transporter atp-binding protein
SA2016_RS15715	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SA2016_RS15720	COG4948	Mandelate Racemase Muconate Lactonizing
SA2016_RS15755	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS15760	COG0022	dehydrogenase e1 component
SA2016_RS15775	COG0076	glutamate decarboxylase activity
SA2016_RS15785	COG1024	Enoyl-CoA hydratase
SA2016_RS15790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SA2016_RS15795	COG2151	metal-sulfur cluster biosynthetic enzyme
SA2016_RS15800	COG3396	Phenylacetate-CoA oxygenase
SA2016_RS15805	COG3460	Phenylacetate-CoA oxygenase
SA2016_RS15810	COG3396	Phenylacetate-CoA oxygenase
SA2016_RS15815	COG1316	TRANSCRIPTIONal
SA2016_RS15820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SA2016_RS15825	COG3206	protein involved in exopolysaccharide biosynthesis
SA2016_RS15825	COG0489	protein tyrosine kinase activity
SA2016_RS15840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SA2016_RS15845	COG0857	belongs to the CobB CobQ family
SA2016_RS15845	COG0280	phosphate acetyltransferase
SA2016_RS15850	COG2050	protein possibly involved in aromatic compounds catabolism
SA2016_RS15875	COG2133	pyrroloquinoline quinone binding
SA2016_RS15880	COG0246	Mannitol dehydrogenase
SA2016_RS15885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA2016_RS15885	COG2213	PTS system mannitol-specific
SA2016_RS15900	COG2706	6-phosphogluconolactonase activity
SA2016_RS15905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SA2016_RS15915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SA2016_RS15920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SA2016_RS15930	COG2814	Major facilitator Superfamily
SA2016_RS15930	COG0477	Major facilitator Superfamily
SA2016_RS15935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SA2016_RS15950	COG2030	dehydratase
SA2016_RS15950	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS15975	COG1250	3-hydroxyacyl-CoA dehydrogenase
SA2016_RS15980	COG1024	Enoyl-CoA hydratase
SA2016_RS16000	COG0488	(ABC) transporter
SA2016_RS16015	COG0039	L-malate dehydrogenase activity
SA2016_RS16025	COG0673	inositol 2-dehydrogenase activity
SA2016_RS16035	COG0765	amino acid transport
SA2016_RS16045	COG1609	Transcriptional regulator
SA2016_RS16050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SA2016_RS16090	COG0785	Cytochrome C biogenesis protein
SA2016_RS16095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SA2016_RS16100	COG0406	alpha-ribazole phosphatase activity
SA2016_RS16110	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS16140	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SA2016_RS16160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SA2016_RS16195	COG1063	alcohol dehydrogenase
SA2016_RS16200	COG0183	Belongs to the thiolase family
SA2016_RS16215	COG1414	Transcriptional regulator
SA2016_RS16230	COG0640	Transcriptional regulator
SA2016_RS16235	COG0123	including yeast histone deacetylase and acetoin utilization protein
SA2016_RS16240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SA2016_RS16245	COG0569	domain protein
SA2016_RS16260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SA2016_RS16270	COG1082	Xylose isomerase domain protein TIM barrel
SA2016_RS16275	COG0248	Ppx GppA phosphatase
SA2016_RS16285	COG1754	DNA topoisomerase type I activity
SA2016_RS16285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SA2016_RS16295	COG2890	protein-(glutamine-N5) methyltransferase activity
SA2016_RS16305	COG1054	Belongs to the UPF0176 family
SA2016_RS16315	COG1205	dead DEAH box helicase
SA2016_RS16315	COG1111	helicase
SA2016_RS16375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA2016_RS16380	COG1609	Transcriptional regulator
SA2016_RS16405	COG0395	ABC-type sugar transport system, permease component
SA2016_RS16410	COG1349	DNA-binding transcription factor activity
SA2016_RS16415	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SA2016_RS16440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SA2016_RS16445	COG1408	metallophosphoesterase
SA2016_RS16450	COG1132	(ABC) transporter
SA2016_RS16455	COG1132	(ABC) transporter
SA2016_RS16480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SA2016_RS16485	COG0151	Belongs to the GarS family
SA2016_RS16505	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SA2016_RS16520	COG1414	Transcriptional regulator
SA2016_RS16530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SA2016_RS16540	COG3257	ureidoglycine aminohydrolase activity
SA2016_RS16550	COG3622	Belongs to the hyi family
SA2016_RS16555	COG2084	Dehydrogenase
SA2016_RS16560	COG3960	tartronate-semialdehyde synthase activity
SA2016_RS16565	COG1929	Belongs to the glycerate kinase type-1 family
SA2016_RS16570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SA2016_RS16595	COG2233	PERMEase
SA2016_RS16610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SA2016_RS16615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SA2016_RS16630	COG0542	response to heat
SA2016_RS16645	COG2353	YceI-like domain
SA2016_RS16650	COG3304	Inner membrane component domain
SA2016_RS16670	COG1473	amidohydrolase
SA2016_RS16675	COG0477	Major facilitator Superfamily
SA2016_RS16680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SA2016_RS16705	COG0789	Transcriptional regulator
SA2016_RS16710	COG0484	heat shock protein binding
SA2016_RS16715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SA2016_RS16720	COG0443	Heat shock 70 kDa protein
SA2016_RS16725	COG0179	Fumarylacetoacetate (FAA) hydrolase
SA2016_RS16730	COG0477	Major facilitator Superfamily
SA2016_RS16745	COG1280	lysine exporter protein (LysE YggA)
SA2016_RS16750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SA2016_RS16760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SA2016_RS16790	COG1846	Transcriptional regulator
SA2016_RS16795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA2016_RS16800	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS16805	COG0243	molybdopterin cofactor binding
SA2016_RS16845	COG0446	pyridine nucleotide-disulphide oxidoreductase
SA2016_RS16845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SA2016_RS16850	COG2508	Transcriptional regulator
SA2016_RS16850	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SA2016_RS16855	COG2066	Belongs to the glutaminase family
SA2016_RS16880	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SA2016_RS16890	COG2376	Dihydroxyacetone kinase
SA2016_RS16895	COG0698	ribose 5-phosphate isomerase
SA2016_RS16900	COG0149	triose-phosphate isomerase activity
SA2016_RS16910	COG2271	Major facilitator Superfamily
SA2016_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS16920	COG1250	3-hydroxyacyl-CoA dehydrogenase
SA2016_RS16930	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SA2016_RS16935	COG2860	membrane
SA2016_RS16940	COG0667	Aldo Keto reductase
SA2016_RS16955	COG1116	anion transmembrane transporter activity
SA2016_RS16960	COG3290	protein histidine kinase activity
SA2016_RS17010	COG2271	Major facilitator Superfamily
SA2016_RS17025	COG1017	nitric oxide dioxygenase activity
SA2016_RS17025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SA2016_RS17040	COG0702	epimerase
SA2016_RS17060	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS17110	COG1414	Transcriptional regulator
SA2016_RS17115	COG1012	belongs to the aldehyde dehydrogenase family
SA2016_RS17125	COG4176	ABC-type proline glycine betaine transport system permease component
SA2016_RS17130	COG4175	Glycine betaine
SA2016_RS17130	COG0517	IMP dehydrogenase activity
SA2016_RS17165	COG0300	oxidoreductase activity
SA2016_RS17170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SA2016_RS17235	COG3959	Transketolase, thiamine diphosphate binding domain
SA2016_RS17240	COG0477	Major facilitator Superfamily
SA2016_RS17250	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS17255	COG2376	Dihydroxyacetone kinase
SA2016_RS17260	COG0698	ribose 5-phosphate isomerase
SA2016_RS17275	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SA2016_RS17285	COG1793	dna ligase
SA2016_RS17285	COG3285	dna ligase
SA2016_RS17290	COG4336	lyase activity
SA2016_RS17295	COG2814	Major facilitator Superfamily
SA2016_RS17300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SA2016_RS17305	COG1984	allophanate hydrolase subunit 2
SA2016_RS17310	COG4770	biotin carboxylase activity
SA2016_RS17345	COG0386	Belongs to the glutathione peroxidase family
SA2016_RS17355	COG1063	alcohol dehydrogenase
SA2016_RS17360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SA2016_RS17375	COG1122	ATPase activity
SA2016_RS17380	COG4721	ABC-type cobalt transport system, permease component
SA2016_RS17390	COG1320	monovalent cation:proton antiporter activity
SA2016_RS17400	COG1863	multisubunit Na H antiporter MnhE subunit
SA2016_RS17405	COG0651	ATP synthesis coupled electron transport
SA2016_RS17410	COG1006	Multisubunit Na H antiporter MnhC subunit
SA2016_RS17415	COG2111	Na H antiporter
SA2016_RS17415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SA2016_RS17430	COG0475	glutathione-regulated potassium exporter activity
SA2016_RS17440	COG1556	Lactate utilization protein
SA2016_RS17445	COG1139	Iron-sulfur cluster binding protein
SA2016_RS17450	COG0247	lactate metabolic process
SA2016_RS17455	COG0277	FAD linked oxidase domain protein
SA2016_RS17460	COG1620	l-lactate permease
SA2016_RS17465	COG2186	Transcriptional regulator
SA2016_RS17475	COG0717	Belongs to the dCTP deaminase family
SA2016_RS17495	COG0531	amino acid
SA2016_RS17520	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SA2016_RS17545	COG3336	cytochrome c oxidase
SA2016_RS17550	COG0776	regulation of translation
SA2016_RS17565	COG1131	(ABC) transporter
SA2016_RS17585	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SA2016_RS17590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SA2016_RS17595	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SA2016_RS17640	COG1113	amino acid transport
SA2016_RS17665	COG1960	acyl-CoA dehydrogenase activity
SA2016_RS17685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SA2016_RS17690	COG0435	Glutathione S-transferase
SA2016_RS17695	COG0765	amino acid transport
SA2016_RS17700	COG0765	amino acid transport
SA2016_RS17705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SA2016_RS17720	COG1024	Enoyl-CoA hydratase
SA2016_RS17765	COG0246	Mannitol dehydrogenase
SA2016_RS17770	COG2721	sulfolactate sulfo-lyase activity
SA2016_RS17775	COG1609	Transcriptional regulator
SA2016_RS17780	COG1904	glucuronate isomerase
SA2016_RS17785	COG2211	Major facilitator Superfamily
SA2016_RS17800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SA2016_RS17805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SA2016_RS17820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SA2016_RS17840	COG1316	TRANSCRIPTIONal
SA2016_RS17880	COG3853	Toxic anion resistance protein (TelA)
SA2016_RS17915	COG1358	cellular component organization or biogenesis
SA2016_RS17925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA2016_RS17965	COG2211	Major facilitator Superfamily
SA2016_RS17975	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SA2016_RS17985	COG2132	Multicopper oxidase
SA2016_RS18005	COG0640	Transcriptional regulator
SA2016_RS18040	COG2217	Heavy metal translocating P-type atpase
SA2016_RS18050	COG0477	Major facilitator Superfamily
SA2016_RS18070	COG0477	Major facilitator Superfamily
SA2016_RS18080	COG1113	amino acid transport
SA2016_RS18095	COG0686	Belongs to the AlaDH PNT family
SA2016_RS18105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SA2016_RS18110	COG0697	spore germination
SA2016_RS18115	COG1846	Transcriptional regulator
SA2016_RS18130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SA2016_RS18150	COG1191	sigma factor activity
SA2016_RS18155	COG1309	transcriptional regulator
SA2016_RS18170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SA2016_RS18190	COG0531	amino acid
SA2016_RS18205	COG0583	DNA-binding transcription factor activity
SA2016_RS18210	COG2828	Protein conserved in bacteria
SA2016_RS18215	COG1301	dicarboxylic acid transport
SA2016_RS18225	COG0477	Major facilitator Superfamily
SA2016_RS18235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SA2016_RS18245	COG0800	Aldolase
SA2016_RS18250	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
SA2016_RS18255	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS18260	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SA2016_RS18265	COG0477	Major facilitator Superfamily
SA2016_RS18270	COG1609	Transcriptional regulator
SA2016_RS18285	COG3347	Dehydrogenase
SA2016_RS18285	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS18290	COG1070	Carbohydrate kinase
SA2016_RS18310	COG1064	alcohol dehydrogenase
SA2016_RS18335	COG0318	PFAM AMP-dependent synthetase and ligase
SA2016_RS18395	COG0477	Major facilitator Superfamily
SA2016_RS18400	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA2016_RS18405	COG0022	dehydrogenase e1 component
SA2016_RS18415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SA2016_RS18420	COG1950	PFAM Membrane protein of
SA2016_RS18435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SA2016_RS18475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SA2016_RS18480	COG2957	Belongs to the agmatine deiminase family
SA2016_RS18485	COG0531	amino acid
SA2016_RS18500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SA2016_RS18515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SA2016_RS18520	COG1473	amidohydrolase
SA2016_RS18535	COG1132	(ABC) transporter
SA2016_RS18540	COG1695	Transcriptional regulator
SA2016_RS18545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SA2016_RS18575	COG1414	Transcriptional regulator
SA2016_RS18605	COG2271	Major facilitator Superfamily
SA2016_RS18610	COG1070	Carbohydrate kinase
SA2016_RS18615	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS18620	COG0277	FAD linked oxidase domain protein
SA2016_RS18625	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SA2016_RS18640	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS18650	COG0439	Biotin carboxylase
SA2016_RS18675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA2016_RS18680	COG1414	Transcriptional regulator
SA2016_RS18725	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SA2016_RS18735	COG0251	oxidation-reduction process
SA2016_RS18740	COG0477	Major facilitator Superfamily
SA2016_RS18755	COG2271	Major facilitator Superfamily
SA2016_RS18770	COG1304	FMN binding
SA2016_RS18790	COG0154	amidase activity
SA2016_RS18805	COG0693	protein deglycase activity
SA2016_RS18810	COG4974	Belongs to the 'phage' integrase family
SA2016_RS18830	COG2732	(Barnase) inhibitor
SA2016_RS18840	COG0154	amidase activity
SA2016_RS18845	COG0402	S-adenosylhomocysteine deaminase activity
SA2016_RS18890	COG1335	isochorismatase
SA2016_RS18895	COG0747	negative chemotaxis
SA2016_RS18915	COG4608	Belongs to the ABC transporter superfamily
SA2016_RS18920	COG0444	Belongs to the ABC transporter superfamily
SA2016_RS18925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA2016_RS18930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SA2016_RS18940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SA2016_RS18960	COG1116	anion transmembrane transporter activity
SA2016_RS18970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SA2016_RS18975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SA2016_RS18995	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SA2016_RS19000	COG2149	membrane
SA2016_RS19050	COG1414	Transcriptional regulator
SA2016_RS19060	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SA2016_RS19065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SA2016_RS19075	COG2197	response regulator
SA2016_RS19080	COG0698	ribose 5-phosphate isomerase
SA2016_RS19085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SA2016_RS19115	COG0574	Belongs to the PEP-utilizing enzyme family
SA2016_RS19115	COG3848	Pyruvate phosphate dikinase
SA2016_RS19120	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS19165	COG0129	dihydroxy-acid dehydratase activity
SA2016_RS19185	COG1414	Transcriptional regulator
SA2016_RS19190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SA2016_RS19200	COG0183	Belongs to the thiolase family
SA2016_RS19205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SA2016_RS19215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SA2016_RS19220	COG3485	protocatechuate 3,4-dioxygenase
SA2016_RS19225	COG3485	protocatechuate 3,4-dioxygenase
SA2016_RS19275	COG0531	amino acid
SA2016_RS19280	COG0667	Aldo Keto reductase
SA2016_RS19320	COG5416	Lipopolysaccharide assembly protein A domain
SA2016_RS19330	COG0667	Aldo Keto reductase
SA2016_RS19350	COG1053	succinate dehydrogenase
SA2016_RS19365	COG0673	inositol 2-dehydrogenase activity
SA2016_RS19370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SA2016_RS19375	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS19380	COG0477	Major facilitator Superfamily
SA2016_RS19390	COG0583	DNA-binding transcription factor activity
SA2016_RS19400	COG1063	alcohol dehydrogenase
SA2016_RS19405	COG1053	succinate dehydrogenase
SA2016_RS19430	COG1902	pentaerythritol trinitrate reductase activity
SA2016_RS19450	COG0667	Aldo Keto reductase
SA2016_RS19455	COG2814	Major facilitator Superfamily
SA2016_RS19460	COG0667	Aldo Keto reductase
SA2016_RS19470	COG2814	Major facilitator Superfamily
SA2016_RS19480	COG1846	Transcriptional regulator
SA2016_RS19485	COG2814	Major facilitator Superfamily
SA2016_RS19490	COG4989	oxidoreductase activity
SA2016_RS19500	COG1082	Xylose isomerase domain protein TIM barrel
SA2016_RS19500	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SA2016_RS19505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SA2016_RS19510	COG1414	Transcriptional regulator
SA2016_RS19515	COG1024	Enoyl-CoA hydratase
SA2016_RS19520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SA2016_RS19540	COG0477	Major facilitator Superfamily
SA2016_RS19545	COG3387	PFAM Glycoside hydrolase 15-related
SA2016_RS19550	COG1063	alcohol dehydrogenase
SA2016_RS19555	COG2720	vancomycin resistance protein
SA2016_RS19605	COG3387	PFAM Glycoside hydrolase 15-related
SA2016_RS19615	COG2271	Major facilitator Superfamily
SA2016_RS19620	COG1802	Transcriptional regulator
SA2016_RS19630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SA2016_RS19645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SA2016_RS19650	COG0318	PFAM AMP-dependent synthetase and ligase
SA2016_RS19655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SA2016_RS19665	COG1028	Short-chain dehydrogenase reductase Sdr
SA2016_RS19685	COG0252	asparaginase activity
SA2016_RS19690	COG1609	Transcriptional regulator
SA2016_RS19695	COG1984	allophanate hydrolase subunit 2
SA2016_RS19700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SA2016_RS19705	COG0439	Biotin carboxylase
SA2016_RS19710	COG0511	ligase activity, forming carbon-carbon bonds
SA2016_RS19715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SA2016_RS19720	COG3835	regulator
SA2016_RS19730	COG4124	Belongs to the glycosyl hydrolase 26 family
SA2016_RS19730	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SA2016_RS19735	COG1609	Transcriptional regulator
SA2016_RS19745	COG1175	transmembrane transport
SA2016_RS19760	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
SA2016_RS19775	COG1454	alcohol dehydrogenase
SA2016_RS19785	COG0277	FAD linked oxidase domain protein
SA2016_RS19785	COG0247	lactate metabolic process
SA2016_RS19815	COG1620	l-lactate permease
SA2016_RS19820	COG0277	FAD linked oxidase domain protein
SA2016_RS19825	COG0395	ABC-type sugar transport system, permease component
SA2016_RS19830	COG1175	transmembrane transport
SA2016_RS19845	COG1250	3-hydroxyacyl-CoA dehydrogenase
SA2016_RS19905	COG1937	Protein conserved in bacteria
SA2016_RS19945	COG2226	methyltransferase
SA2016_RS19950	COG1113	amino acid transport
SA2016_RS19960	COG0305	Participates in initiation and elongation during chromosome replication
SA2016_RS19975	COG0431	NADPH-dependent FMN reductase
SA2016_RS19980	COG0359	binds to the 23S rRNA
SA2016_RS19985	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SA2016_RS19995	COG0360	Binds together with S18 to 16S ribosomal RNA
SA2016_RS20005	COG1362	aminopeptidase activity
SA2016_RS20045	COG0477	Major facilitator Superfamily
SA2016_RS20050	COG2197	response regulator
SA2016_RS20055	COG4585	Histidine kinase
SA2016_RS20075	COG1136	(ABC) transporter
SA2016_RS20075	COG0577	efflux transmembrane transporter activity
SA2016_RS20080	COG1136	(ABC) transporter
SA2016_RS20080	COG0577	efflux transmembrane transporter activity
SA2016_RS20090	COG1597	lipid kinase activity
SA2016_RS20095	COG0738	Major facilitator superfamily
SA2016_RS20110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA2016_RS20115	COG0768	penicillin binding
SA2016_RS20130	COG1247	-acetyltransferase
SA2016_RS20135	COG0488	(ABC) transporter
SA2016_RS20155	COG0406	alpha-ribazole phosphatase activity
SA2016_RS20160	COG0617	tRNA 3'-terminal CCA addition
SA2016_RS20180	COG0492	ferredoxin-NADP+ reductase activity
SA2016_RS20185	COG3118	belongs to the thioredoxin family
SA2016_RS20195	COG1192	Involved in chromosome partitioning
SA2016_RS20200	COG0357	Ribosomal RNA small subunit methyltransferase G
SA2016_RS20210	COG0706	membrane insertase activity
SA2016_RS20215	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SA2016_RS20220	COG0594	ribonuclease P activity
SA2016_RS20230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids