locus-tag	class	description
AOX55_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AOX55_RS00010	COG3795	YCII-related domain
AOX55_RS00015	COG4941	Belongs to the sigma-70 factor family
AOX55_RS00055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOX55_RS00060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AOX55_RS00070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AOX55_RS00075	COG1420	regulation of RNA biosynthetic process
AOX55_RS00080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOX55_RS00100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOX55_RS00105	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOX55_RS00110	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AOX55_RS00115	COG1137	ATPase activity
AOX55_RS00120	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AOX55_RS00130	COG0616	signal peptide processing
AOX55_RS00135	COG0776	regulation of translation
AOX55_RS00150	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AOX55_RS00150	COG0116	Belongs to the methyltransferase superfamily
AOX55_RS00155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOX55_RS00160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AOX55_RS00165	COG2205	protein histidine kinase activity
AOX55_RS00165	COG5002	protein histidine kinase activity
AOX55_RS00165	COG0784	Response regulator, receiver
AOX55_RS00175	COG0280	phosphate acetyltransferase
AOX55_RS00175	COG0281	malic enzyme
AOX55_RS00180	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AOX55_RS00185	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AOX55_RS00190	COG0728	peptidoglycan biosynthetic process
AOX55_RS00200	COG0180	Tryptophanyl-tRNA synthetase
AOX55_RS00210	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AOX55_RS00220	COG0456	acetyltransferase
AOX55_RS00230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOX55_RS00235	COG1702	phosphate starvation-inducible protein PhoH
AOX55_RS00240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AOX55_RS00245	COG4535	Mg2 and Co2 transporter CorC
AOX55_RS00255	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AOX55_RS00260	COG1396	sequence-specific DNA binding
AOX55_RS00265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AOX55_RS00270	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOX55_RS00280	COG0071	Belongs to the small heat shock protein (HSP20) family
AOX55_RS00290	COG3385	transposase activity
AOX55_RS00295	COG0840	transmembrane signaling receptor activity
AOX55_RS00300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOX55_RS00310	COG0431	NADPH-dependent FMN reductase
AOX55_RS00315	COG0242	peptide deformylase activity
AOX55_RS00320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AOX55_RS00325	COG0101	tRNA pseudouridine synthase activity
AOX55_RS00335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOX55_RS00350	COG0657	acetylesterase activity
AOX55_RS00355	COG0583	DNA-binding transcription factor activity
AOX55_RS00370	COG2171	N-acyltransferase activity
AOX55_RS00390	COG2169	Transcriptional regulator
AOX55_RS00390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOX55_RS00400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOX55_RS00405	COG1595	DNA-templated transcription, initiation
AOX55_RS00415	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AOX55_RS00420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOX55_RS00430	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AOX55_RS00435	COG0706	membrane insertase activity
AOX55_RS00440	COG0594	ribonuclease P activity
AOX55_RS00445	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AOX55_RS00450	COG0840	transmembrane signaling receptor activity
AOX55_RS00460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOX55_RS00495	COG0667	Aldo Keto reductase
AOX55_RS00515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOX55_RS00520	COG3938	Belongs to the proline racemase family
AOX55_RS00535	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOX55_RS00545	COG2259	Doxx family
AOX55_RS00575	COG1072	(Pantothenic acid kinase))
AOX55_RS00580	COG0418	dihydroorotase activity
AOX55_RS00585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AOX55_RS00600	COG0166	Belongs to the GPI family
AOX55_RS00605	COG0318	PFAM AMP-dependent synthetase and ligase
AOX55_RS00610	COG0628	permease
AOX55_RS00615	COG2205	protein histidine kinase activity
AOX55_RS00630	COG4589	Belongs to the CDS family
AOX55_RS00680	COG0328	RNA-DNA hybrid ribonuclease activity
AOX55_RS00890	COG2326	polyphosphate kinase activity
AOX55_RS00895	COG5002	protein histidine kinase activity
AOX55_RS00905	COG0573	inorganic phosphate transmembrane transporter activity
AOX55_RS00915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOX55_RS00920	COG0704	Plays a role in the regulation of phosphate uptake
AOX55_RS00925	COG0745	RESPONSE REGULATOR receiver
AOX55_RS00935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOX55_RS00940	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOX55_RS00950	COG2967	ApaG domain
AOX55_RS00955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOX55_RS00965	COG0717	Belongs to the dCTP deaminase family
AOX55_RS00975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOX55_RS01020	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOX55_RS01020	COG1024	Enoyl-CoA hydratase
AOX55_RS01025	COG0183	Belongs to the thiolase family
AOX55_RS01030	COG1960	acyl-CoA dehydrogenase activity
AOX55_RS01040	COG0730	response to heat
AOX55_RS01065	COG1201	RNA secondary structure unwinding
AOX55_RS01090	COG0534	Mate efflux family protein
AOX55_RS01095	COG0167	dihydroorotate dehydrogenase activity
AOX55_RS01115	COG0784	Response regulator, receiver
AOX55_RS01115	COG2205	protein histidine kinase activity
AOX55_RS01115	COG2198	Histidine kinase
AOX55_RS01120	COG1970	mechanosensitive ion channel activity
AOX55_RS01125	COG0436	Aminotransferase
AOX55_RS01140	COG1294	oxidase, subunit
AOX55_RS01145	COG1271	oxidase subunit
AOX55_RS01150	COG1473	amidohydrolase
AOX55_RS01160	COG4215	(ABC) transporter
AOX55_RS01165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOX55_RS01175	COG1309	transcriptional regulator
AOX55_RS01210	COG0517	IMP dehydrogenase activity
AOX55_RS01210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AOX55_RS01220	COG1368	sulfuric ester hydrolase activity
AOX55_RS01225	COG0300	oxidoreductase activity
AOX55_RS01230	COG0156	8-amino-7-oxononanoate synthase activity
AOX55_RS01235	COG3321	synthase
AOX55_RS01235	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS01235	COG0604	alcohol dehydrogenase
AOX55_RS01245	COG1335	isochorismatase
AOX55_RS01250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AOX55_RS01265	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOX55_RS01290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOX55_RS01300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOX55_RS01305	COG5328	Belongs to the UPF0262 family
AOX55_RS01315	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOX55_RS01320	COG0424	maF-like protein
AOX55_RS01325	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AOX55_RS01335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AOX55_RS01380	COG4977	sequence-specific DNA binding
AOX55_RS01390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOX55_RS01405	COG4952	isomerase
AOX55_RS01410	COG3347	Dehydrogenase
AOX55_RS01410	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS01415	COG1349	DNA-binding transcription factor activity
AOX55_RS01425	COG1129	ABC transporter
AOX55_RS01440	COG3254	rhamnose metabolic process
AOX55_RS01450	COG0840	transmembrane signaling receptor activity
AOX55_RS01460	COG0745	RESPONSE REGULATOR receiver
AOX55_RS01465	COG2198	Histidine kinase
AOX55_RS01465	COG0643	Histidine kinase
AOX55_RS01470	COG0835	chemotaxis
AOX55_RS01475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOX55_RS01480	COG2201	protein-glutamate methylesterase activity
AOX55_RS01485	COG0745	RESPONSE REGULATOR receiver
AOX55_RS01490	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AOX55_RS01500	COG1766	The M ring may be actively involved in energy transduction
AOX55_RS01505	COG2771	luxR family
AOX55_RS01510	COG2197	response regulator
AOX55_RS01520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOX55_RS01525	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOX55_RS01530	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOX55_RS01535	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOX55_RS01540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AOX55_RS01550	COG4786	Flagellar basal body rod
AOX55_RS01555	COG1157	protein secretion by the type III secretion system
AOX55_RS01565	COG1815	bacterial-type flagellum-dependent cell motility
AOX55_RS01570	COG1558	bacterial-type flagellum-dependent cell motility
AOX55_RS01575	COG1677	Flagellar hook-basal body complex protein FliE
AOX55_RS01580	COG4786	Flagellar basal body rod
AOX55_RS01585	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AOX55_RS01590	COG1706	bacterial-type flagellum-dependent cell motility
AOX55_RS01600	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AOX55_RS01610	COG1338	Plays a role in the flagellum-specific transport system
AOX55_RS01620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOX55_RS01630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOX55_RS01640	COG1360	Flagellar Motor Protein
AOX55_RS01665	COG1749	Flagellar hook protein flgE
AOX55_RS01685	COG5443	negative regulation of bacterial-type flagellum assembly
AOX55_RS01695	COG4794	Type iii secretion
AOX55_RS01700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOX55_RS01735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AOX55_RS01740	COG1609	Transcriptional regulator
AOX55_RS01745	COG1653	transport
AOX55_RS01750	COG1175	transmembrane transport
AOX55_RS01755	COG0395	ABC-type sugar transport system, permease component
AOX55_RS01760	COG0366	Alpha amylase catalytic
AOX55_RS01765	COG3842	ATPase activity
AOX55_RS01780	COG0129	dihydroxy-acid dehydratase activity
AOX55_RS01785	COG0363	glucosamine-6-phosphate deaminase activity
AOX55_RS01790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOX55_RS01795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS01805	COG2081	HI0933 family
AOX55_RS01810	COG0840	transmembrane signaling receptor activity
AOX55_RS01810	COG2972	Histidine kinase
AOX55_RS01845	COG3842	ATPase activity
AOX55_RS01850	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOX55_RS01855	COG1177	transmembrane transport
AOX55_RS01865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOX55_RS01870	COG1178	ABC-type Fe3 transport system permease component
AOX55_RS01875	COG2205	protein histidine kinase activity
AOX55_RS01900	COG4269	membrane
AOX55_RS01910	COG1607	acyl-coa hydrolase
AOX55_RS01915	COG1840	ABC-type Fe3 transport system, periplasmic component
AOX55_RS01920	COG1959	2 iron, 2 sulfur cluster binding
AOX55_RS01925	COG0747	negative chemotaxis
AOX55_RS01930	COG0601	transmembrane transport
AOX55_RS01935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS01940	COG0444	Belongs to the ABC transporter superfamily
AOX55_RS01945	COG4608	Belongs to the ABC transporter superfamily
AOX55_RS01950	COG0251	oxidation-reduction process
AOX55_RS01965	COG0784	Response regulator, receiver
AOX55_RS01990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS02000	COG1285	pathogenesis
AOX55_RS02060	COG0582	viral genome integration into host DNA
AOX55_RS02110	COG0270	DNA (cytosine-5-)-methyltransferase activity
AOX55_RS02145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOX55_RS02200	COG4372	Transposase
AOX55_RS02220	COG3436	PFAM IS66 Orf2 family protein
AOX55_RS02255	COG0248	Ppx GppA phosphatase
AOX55_RS02255	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOX55_RS02260	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AOX55_RS02270	COG0477	Major facilitator Superfamily
AOX55_RS02300	COG0583	DNA-binding transcription factor activity
AOX55_RS02305	COG0583	DNA-binding transcription factor activity
AOX55_RS02330	COG0306	phosphate transporter
AOX55_RS02340	COG1725	Transcriptional regulator
AOX55_RS02350	COG0583	DNA-binding transcription factor activity
AOX55_RS02355	COG0277	FAD linked oxidase domain protein
AOX55_RS02360	COG0277	FAD linked oxidase domain protein
AOX55_RS02370	COG0247	lactate metabolic process
AOX55_RS02375	COG3385	transposase activity
AOX55_RS02380	COG1376	ErfK ybiS ycfS ynhG family protein
AOX55_RS02380	COG1388	LysM domain
AOX55_RS02385	COG1376	ErfK ybiS ycfS ynhG family protein
AOX55_RS02390	COG2818	Glycosylase
AOX55_RS02410	COG0124	histidyl-tRNA synthetase
AOX55_RS02415	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AOX55_RS02420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOX55_RS02425	COG0625	glutathione transferase activity
AOX55_RS02435	COG3300	MHYT domain
AOX55_RS02435	COG5001	Diguanylate cyclase
AOX55_RS02440	COG0459	protein refolding
AOX55_RS02445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOX55_RS02465	COG0196	riboflavin kinase activity
AOX55_RS02470	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOX55_RS02485	COG0590	tRNA wobble adenosine to inosine editing
AOX55_RS02490	COG1187	pseudouridine synthase activity
AOX55_RS02495	COG0742	ribosomal rna small subunit methyltransferase
AOX55_RS02505	COG0475	glutathione-regulated potassium exporter activity
AOX55_RS02505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOX55_RS02510	COG0312	modulator of DNA gyrase
AOX55_RS02515	COG0483	inositol monophosphate 1-phosphatase activity
AOX55_RS02525	COG1519	Transferase
AOX55_RS02535	COG1663	tetraacyldisaccharide 4'-kinase activity
AOX55_RS02545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AOX55_RS02555	COG3300	MHYT domain
AOX55_RS02555	COG5001	Diguanylate cyclase
AOX55_RS02565	COG0129	dihydroxy-acid dehydratase activity
AOX55_RS02570	COG3386	PFAM SMP-30 Gluconolaconase
AOX55_RS02575	COG0800	Aldolase
AOX55_RS02580	COG3734	2-keto-3-deoxy-galactonokinase
AOX55_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS02590	COG1414	Transcriptional regulator
AOX55_RS02600	COG2771	luxR family
AOX55_RS02620	COG0489	protein tyrosine kinase activity
AOX55_RS02630	COG0598	Magnesium transport protein CorA
AOX55_RS02635	COG3158	transport of potassium into the cell
AOX55_RS02650	COG0356	it plays a direct role in the translocation of protons across the membrane
AOX55_RS02655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOX55_RS02660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOX55_RS02665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOX55_RS02675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AOX55_RS02695	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOX55_RS02700	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOX55_RS02710	COG0142	geranyltranstransferase activity
AOX55_RS02735	COG0752	glycyl-tRNA synthetase alpha subunit
AOX55_RS02745	COG1704	LemA family
AOX55_RS02755	COG0751	glycine-tRNA ligase activity
AOX55_RS02775	COG1683	Conserved Protein
AOX55_RS02785	COG0151	Belongs to the GarS family
AOX55_RS02790	COG5001	Diguanylate cyclase
AOX55_RS02800	COG2223	nitrite transmembrane transporter activity
AOX55_RS02810	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOX55_RS02835	COG0009	L-threonylcarbamoyladenylate synthase
AOX55_RS02855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOX55_RS02870	COG1960	acyl-CoA dehydrogenase activity
AOX55_RS02875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOX55_RS02880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOX55_RS02890	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AOX55_RS02895	COG1741	Belongs to the pirin family
AOX55_RS02900	COG1722	exodeoxyribonuclease VII activity
AOX55_RS02905	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOX55_RS02910	COG0604	alcohol dehydrogenase
AOX55_RS02920	COG0183	Belongs to the thiolase family
AOX55_RS02925	COG0318	PFAM AMP-dependent synthetase and ligase
AOX55_RS02930	COG1268	BioY protein
AOX55_RS02935	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AOX55_RS02940	COG1122	ATPase activity
AOX55_RS02945	COG3214	Protein conserved in bacteria
AOX55_RS02950	COG0312	modulator of DNA gyrase
AOX55_RS02960	COG1686	Belongs to the peptidase S11 family
AOX55_RS02970	COG0259	pyridoxamine-phosphate oxidase activity
AOX55_RS02980	COG0484	heat shock protein binding
AOX55_RS02985	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOX55_RS03000	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AOX55_RS03020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOX55_RS03025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOX55_RS03030	COG0109	protoheme IX farnesyltransferase activity
AOX55_RS03040	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AOX55_RS03060	COG3346	SURF1 family
AOX55_RS03065	COG3759	membrane
AOX55_RS03070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOX55_RS03075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOX55_RS03080	COG0328	RNA-DNA hybrid ribonuclease activity
AOX55_RS03090	COG0678	peroxiredoxin activity
AOX55_RS03090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOX55_RS03100	COG1678	Uncharacterized ACR, COG1678
AOX55_RS03105	COG5001	Diguanylate cyclase
AOX55_RS03110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOX55_RS03115	COG0612	Peptidase, M16
AOX55_RS03135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOX55_RS03170	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AOX55_RS03200	COG2852	Protein conserved in bacteria
AOX55_RS03205	COG1196	nuclear chromosome segregation
AOX55_RS03210	COG0574	Belongs to the PEP-utilizing enzyme family
AOX55_RS03210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOX55_RS03255	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AOX55_RS03260	COG0058	SHG alpha-glucan phosphorylase activity
AOX55_RS03270	COG0517	IMP dehydrogenase activity
AOX55_RS03275	COG3422	double-strand break repair
AOX55_RS03300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOX55_RS03310	COG4176	ABC-type proline glycine betaine transport system permease component
AOX55_RS03315	COG4175	Glycine betaine
AOX55_RS03315	COG3448	diguanylate cyclase activity
AOX55_RS03340	COG4221	oxidoreductase activity
AOX55_RS03355	COG4638	Rieske (2fe-2S)
AOX55_RS03360	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS03365	COG3246	L-lysine catabolic process to acetate
AOX55_RS03370	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS03375	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS03390	COG0633	Ferredoxin
AOX55_RS03395	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOX55_RS03395	COG0824	Thioesterase
AOX55_RS03460	COG4372	Transposase
AOX55_RS03595	COG0456	acetyltransferase
AOX55_RS03625	COG0431	NADPH-dependent FMN reductase
AOX55_RS03630	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOX55_RS03635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOX55_RS03655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOX55_RS03670	COG2186	Transcriptional regulator
AOX55_RS03740	COG1525	nuclease
AOX55_RS03880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOX55_RS03925	COG2895	sulfate adenylyltransferase (ATP) activity
AOX55_RS03930	COG0175	sulfate reduction
AOX55_RS03935	COG0175	sulfate reduction
AOX55_RS03950	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AOX55_RS03955	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS03960	COG3119	arylsulfatase activity
AOX55_RS03965	COG1309	transcriptional regulator
AOX55_RS04015	COG0583	DNA-binding transcription factor activity
AOX55_RS04025	COG1388	LysM domain
AOX55_RS04025	COG1376	ErfK ybiS ycfS ynhG family protein
AOX55_RS04030	COG1846	Transcriptional regulator
AOX55_RS04035	COG1764	response to oxidative stress
AOX55_RS04040	COG2824	Alkylphosphonate utilization operon protein PhnA
AOX55_RS04045	COG0433	COG0433 Predicted ATPase
AOX55_RS04060	COG4106	trans-aconitate 2-methyltransferase activity
AOX55_RS04080	COG2814	Major facilitator Superfamily
AOX55_RS04100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOX55_RS04120	COG2010	Cytochrome c
AOX55_RS04130	COG0789	Transcriptional regulator
AOX55_RS04140	COG4993	Dehydrogenase
AOX55_RS04145	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AOX55_RS04165	COG2514	catechol 2,3-dioxygenase activity
AOX55_RS04185	COG1272	protein, Hemolysin III
AOX55_RS04195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOX55_RS04205	COG2111	Na H antiporter
AOX55_RS04205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOX55_RS04210	COG2111	Na H antiporter
AOX55_RS04215	COG1006	Multisubunit Na H antiporter MnhC subunit
AOX55_RS04225	COG1863	multisubunit Na H antiporter MnhE subunit
AOX55_RS04230	COG2212	antiporter activity
AOX55_RS04235	COG1320	monovalent cation:proton antiporter activity
AOX55_RS04245	COG4957	zinc ion binding
AOX55_RS04255	COG2166	iron-sulfur cluster assembly
AOX55_RS04265	COG2205	protein histidine kinase activity
AOX55_RS04310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOX55_RS04315	COG2983	Belongs to the UPF0260 family
AOX55_RS04355	COG4235	cytochrome complex assembly
AOX55_RS04360	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AOX55_RS04365	COG1138	Cytochrome C-type biogenesis protein
AOX55_RS04370	COG3088	subunit of a heme lyase
AOX55_RS04375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOX55_RS04380	COG0745	RESPONSE REGULATOR receiver
AOX55_RS04385	COG2205	protein histidine kinase activity
AOX55_RS04390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOX55_RS04395	COG2205	protein histidine kinase activity
AOX55_RS04395	COG2202	Pas domain
AOX55_RS04400	COG0308	aminopeptidase N
AOX55_RS04425	COG0443	Heat shock 70 kDa protein
AOX55_RS04440	COG4176	ABC-type proline glycine betaine transport system permease component
AOX55_RS04450	COG1522	sequence-specific DNA binding
AOX55_RS04460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AOX55_RS04465	COG0463	Glycosyl transferase, family 2
AOX55_RS04475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOX55_RS04490	COG0625	glutathione transferase activity
AOX55_RS04505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOX55_RS04525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AOX55_RS04535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AOX55_RS04545	COG0741	lytic transglycosylase activity
AOX55_RS04550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOX55_RS04555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AOX55_RS04565	COG1758	RNA polymerase activity
AOX55_RS04585	COG0736	holo-[acyl-carrier-protein] synthase activity
AOX55_RS04590	COG0681	Belongs to the peptidase S26 family
AOX55_RS04595	COG0571	ribonuclease III activity
AOX55_RS04600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOX55_RS04605	COG0584	glycerophosphoryl diester phosphodiesterase
AOX55_RS04610	COG0435	Glutathione S-transferase
AOX55_RS04615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOX55_RS04620	COG2183	response to ionizing radiation
AOX55_RS04630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOX55_RS04635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOX55_RS04655	COG1376	ErfK ybiS ycfS ynhG family protein
AOX55_RS04660	COG1381	Involved in DNA repair and RecF pathway recombination
AOX55_RS04675	COG1418	mRNA catabolic process
AOX55_RS04690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOX55_RS04695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOX55_RS04705	COG2032	superoxide dismutase activity
AOX55_RS04720	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AOX55_RS04750	COG2135	peptidase activity
AOX55_RS04755	COG0215	cysteine-tRNA ligase activity
AOX55_RS04780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOX55_RS04800	COG5265	(ABC) transporter
AOX55_RS04805	COG0688	phosphatidylethanolamine metabolic process
AOX55_RS04815	COG4221	oxidoreductase activity
AOX55_RS04820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AOX55_RS04835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOX55_RS04845	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AOX55_RS04855	COG0305	Participates in initiation and elongation during chromosome replication
AOX55_RS04865	COG0359	binds to the 23S rRNA
AOX55_RS04875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AOX55_RS04880	COG0360	Binds together with S18 to 16S ribosomal RNA
AOX55_RS04895	COG0667	Aldo Keto reductase
AOX55_RS04900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AOX55_RS04910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOX55_RS04915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOX55_RS04925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOX55_RS04930	COG1561	YicC-like family, N-terminal region
AOX55_RS04935	COG0194	GDP metabolic process
AOX55_RS04940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOX55_RS04945	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOX55_RS04975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOX55_RS04995	COG0488	(ABC) transporter
AOX55_RS05020	COG0105	UTP biosynthetic process
AOX55_RS05045	COG0314	molybdopterin synthase activity
AOX55_RS05055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOX55_RS05060	COG0322	excinuclease ABC activity
AOX55_RS05075	COG0625	glutathione transferase activity
AOX55_RS05090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AOX55_RS05095	COG0243	molybdopterin cofactor binding
AOX55_RS05105	COG0392	lysyltransferase activity
AOX55_RS05105	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AOX55_RS05115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOX55_RS05120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AOX55_RS05125	COG0628	permease
AOX55_RS05135	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOX55_RS05140	COG0248	Ppx GppA phosphatase
AOX55_RS05155	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOX55_RS05160	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AOX55_RS05165	COG2132	Multicopper oxidase
AOX55_RS05175	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AOX55_RS05185	COG0459	protein refolding
AOX55_RS05200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOX55_RS05215	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AOX55_RS05225	COG0113	porphobilinogen synthase activity
AOX55_RS05240	COG2989	Protein conserved in bacteria
AOX55_RS05245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOX55_RS05250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOX55_RS05255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOX55_RS05255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOX55_RS05270	COG0519	Catalyzes the synthesis of GMP from XMP
AOX55_RS05280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AOX55_RS05285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOX55_RS05290	COG2814	Major facilitator Superfamily
AOX55_RS05295	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AOX55_RS05315	COG0416	fatty acid biosynthetic process
AOX55_RS05320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOX55_RS05325	COG0776	regulation of translation
AOX55_RS05355	COG0826	peptidase U32
AOX55_RS05365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AOX55_RS05400	COG3256	nitric oxide reductase
AOX55_RS05405	COG0714	Associated with various cellular activities
AOX55_RS05420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOX55_RS05440	COG2151	metal-sulfur cluster biosynthetic enzyme
AOX55_RS05470	COG4459	periplasmic nitrate reductase
AOX55_RS05495	COG3005	denitrification pathway
AOX55_RS05515	COG2832	Protein of unknown function (DUF454)
AOX55_RS05545	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS05555	COG0489	protein tyrosine kinase activity
AOX55_RS05555	COG3206	protein involved in exopolysaccharide biosynthesis
AOX55_RS05565	COG0110	maltose O-acetyltransferase activity
AOX55_RS05580	COG1612	heme a metabolic process
AOX55_RS05585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AOX55_RS05590	COG0010	Belongs to the arginase family
AOX55_RS05595	COG2329	Antibiotic biosynthesis monooxygenase
AOX55_RS05600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOX55_RS05605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AOX55_RS05615	COG1024	Enoyl-CoA hydratase
AOX55_RS05625	COG1832	CoA-binding protein
AOX55_RS05650	COG2124	cytochrome p450
AOX55_RS05660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOX55_RS05665	COG0740	serine-type endopeptidase activity
AOX55_RS05670	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AOX55_RS05680	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOX55_RS05685	COG0776	regulation of translation
AOX55_RS05700	COG0840	transmembrane signaling receptor activity
AOX55_RS05705	COG0420	3'-5' exonuclease activity
AOX55_RS05710	COG4717	serine-type aminopeptidase activity
AOX55_RS05750	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOX55_RS05755	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOX55_RS05760	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOX55_RS05765	COG0649	NAD binding
AOX55_RS05775	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AOX55_RS05780	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AOX55_RS05785	COG0052	Belongs to the universal ribosomal protein uS2 family
AOX55_RS05795	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AOX55_RS05800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOX55_RS05810	COG0713	ATP synthesis coupled electron transport
AOX55_RS05825	COG1007	ATP synthesis coupled electron transport
AOX55_RS05840	COG0346	lactoylglutathione lyase activity
AOX55_RS05850	COG0442	prolyl-tRNA aminoacylation
AOX55_RS05860	COG1136	(ABC) transporter
AOX55_RS05905	COG0784	Response regulator, receiver
AOX55_RS05915	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOX55_RS05935	COG0557	exoribonuclease II activity
AOX55_RS05940	COG1754	DNA topoisomerase type I activity
AOX55_RS05940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOX55_RS05945	COG0758	DNA mediated transformation
AOX55_RS05950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOX55_RS05960	COG0540	Belongs to the ATCase OTCase family
AOX55_RS05965	COG1960	acyl-CoA dehydrogenase activity
AOX55_RS06000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOX55_RS06005	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AOX55_RS06010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOX55_RS06015	COG0154	amidase activity
AOX55_RS06020	COG0456	acetyltransferase
AOX55_RS06025	COG3811	Belongs to the UPF0386 family
AOX55_RS06030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOX55_RS06060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AOX55_RS06065	COG0439	Biotin carboxylase
AOX55_RS06075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOX55_RS06085	COG0436	Aminotransferase
AOX55_RS06105	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOX55_RS06120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOX55_RS06135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOX55_RS06145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOX55_RS06160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOX55_RS06165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOX55_RS06185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOX55_RS06190	COG0081	regulation of translation
AOX55_RS06195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AOX55_RS06200	COG0222	ribosome binding
AOX55_RS06205	COG0085	RNA polymerase activity
AOX55_RS06210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOX55_RS06220	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AOX55_RS06225	COG0049	tRNA binding
AOX55_RS06230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOX55_RS06235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOX55_RS06240	COG0051	transcription antitermination factor activity, RNA binding
AOX55_RS06245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AOX55_RS06250	COG0088	Forms part of the polypeptide exit tunnel
AOX55_RS06255	COG0089	rRNA binding
AOX55_RS06260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AOX55_RS06265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AOX55_RS06270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AOX55_RS06275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AOX55_RS06280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AOX55_RS06285	COG0255	Belongs to the universal ribosomal protein uL29 family
AOX55_RS06290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOX55_RS06295	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AOX55_RS06300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AOX55_RS06305	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AOX55_RS06310	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AOX55_RS06315	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AOX55_RS06320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AOX55_RS06325	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AOX55_RS06330	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AOX55_RS06335	COG1841	ribosomal large subunit assembly
AOX55_RS06340	COG0200	Binds to the 23S rRNA
AOX55_RS06345	COG0201	protein transport
AOX55_RS06350	COG0563	adenylate kinase activity
AOX55_RS06355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AOX55_RS06360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AOX55_RS06365	COG0202	RNA polymerase activity
AOX55_RS06370	COG0203	ribosomal protein L17
AOX55_RS06375	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AOX55_RS06380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AOX55_RS06385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOX55_RS06390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOX55_RS06405	COG0546	phosphoglycolate phosphatase activity
AOX55_RS06410	COG0564	pseudouridine synthase activity
AOX55_RS06420	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOX55_RS06430	COG1671	Belongs to the UPF0178 family
AOX55_RS06435	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AOX55_RS06455	COG0321	lipoyl(octanoyl) transferase activity
AOX55_RS06465	COG2766	serine protein kinase
AOX55_RS06470	COG2718	Belongs to the UPF0229 family
AOX55_RS06475	COG2719	SpoVR family
AOX55_RS06490	COG0242	peptide deformylase activity
AOX55_RS06495	COG2239	Acts as a magnesium transporter
AOX55_RS06525	COG1760	l-serine dehydratase
AOX55_RS06580	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AOX55_RS06585	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOX55_RS06590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOX55_RS06595	COG0302	gtp cyclohydrolase
AOX55_RS06600	COG0822	iron-sulfur transferase activity
AOX55_RS06605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AOX55_RS06620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOX55_RS06640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOX55_RS06665	COG0187	DNA topoisomerase II activity
AOX55_RS06675	COG0277	FAD linked oxidase domain protein
AOX55_RS06690	COG0149	triose-phosphate isomerase activity
AOX55_RS06695	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOX55_RS06700	COG0504	CTP synthase activity
AOX55_RS06710	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AOX55_RS06715	COG0148	phosphopyruvate hydratase activity
AOX55_RS06725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOX55_RS06730	COG0022	dehydrogenase e1 component
AOX55_RS06730	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOX55_RS06735	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOX55_RS06750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOX55_RS06760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOX55_RS06775	COG2867	negative regulation of translational initiation
AOX55_RS06780	COG1546	Belongs to the CinA family
AOX55_RS06780	COG1058	Belongs to the CinA family
AOX55_RS06785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AOX55_RS06785	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AOX55_RS06795	COG3852	Histidine kinase
AOX55_RS06800	COG2204	response regulator
AOX55_RS06810	COG2204	response regulator
AOX55_RS06815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOX55_RS06820	COG1923	regulation of RNA biosynthetic process
AOX55_RS06825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOX55_RS06830	COG3956	TIGRFAM MazG family protein
AOX55_RS06840	COG1648	precorrin-2 dehydrogenase activity
AOX55_RS06840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOX55_RS06850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOX55_RS06870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOX55_RS06875	COG1126	abc transporter atp-binding protein
AOX55_RS06880	COG0765	amino acid transport
AOX55_RS06885	COG4597	amino acid ABC transporter
AOX55_RS06890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOX55_RS06895	COG0626	cystathionine gamma-synthase activity
AOX55_RS06930	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOX55_RS06950	COG0537	adenosine 5'-monophosphoramidase activity
AOX55_RS06975	COG0052	Belongs to the universal ribosomal protein uS2 family
AOX55_RS06980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AOX55_RS06985	COG0528	UMP kinase activity
AOX55_RS06990	COG0233	cytoplasmic translational termination
AOX55_RS06995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOX55_RS07005	COG0750	zinc metalloprotease
AOX55_RS07015	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOX55_RS07020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOX55_RS07025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOX55_RS07035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOX55_RS07040	COG0372	Belongs to the citrate synthase family
AOX55_RS07055	COG0848	biopolymer transport protein
AOX55_RS07060	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOX55_RS07080	COG0525	valine-tRNA ligase activity
AOX55_RS07095	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AOX55_RS07115	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AOX55_RS07120	COG0018	arginyl-trna synthetase
AOX55_RS07130	COG1472	Belongs to the glycosyl hydrolase 3 family
AOX55_RS07135	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOX55_RS07140	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOX55_RS07145	COG3842	ATPase activity
AOX55_RS07150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOX55_RS07155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOX55_RS07160	COG0805	protein transport
AOX55_RS07165	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AOX55_RS07170	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AOX55_RS07175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOX55_RS07195	COG1862	Preprotein translocase
AOX55_RS07230	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AOX55_RS07260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOX55_RS07265	COG0745	RESPONSE REGULATOR receiver
AOX55_RS07270	COG2205	protein histidine kinase activity
AOX55_RS07320	COG0028	Belongs to the TPP enzyme family
AOX55_RS07325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOX55_RS07335	COG1175	transmembrane transport
AOX55_RS07340	COG0395	ABC-type sugar transport system, permease component
AOX55_RS07365	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOX55_RS07380	COG0598	Magnesium transport protein CorA
AOX55_RS07385	COG2003	Belongs to the UPF0758 family
AOX55_RS07390	COG0024	Methionine aminopeptidase
AOX55_RS07395	COG1489	DNA binding
AOX55_RS07400	COG3243	poly(R)-hydroxyalkanoic acid synthase
AOX55_RS07410	COG0436	Aminotransferase
AOX55_RS07475	COG1278	Cold shock
AOX55_RS07525	COG4372	Transposase
AOX55_RS07545	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AOX55_RS07580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOX55_RS07590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOX55_RS07615	COG1132	(ABC) transporter
AOX55_RS07620	COG1595	DNA-templated transcription, initiation
AOX55_RS07660	COG1082	Xylose isomerase domain protein TIM barrel
AOX55_RS07665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOX55_RS07670	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOX55_RS07675	COG4605	iron ion homeostasis
AOX55_RS07685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOX55_RS07745	COG1396	sequence-specific DNA binding
AOX55_RS07745	COG3800	Transcriptional regulator
AOX55_RS07775	COG0785	Cytochrome C biogenesis protein
AOX55_RS07780	COG0679	Auxin Efflux Carrier
AOX55_RS07785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOX55_RS07790	COG1183	phosphatidylcholine synthase activity
AOX55_RS07800	COG3845	ABC transporter
AOX55_RS07805	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS07810	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS07820	COG2186	Transcriptional regulator
AOX55_RS07825	COG1253	flavin adenine dinucleotide binding
AOX55_RS07845	COG0303	'Molybdopterin
AOX55_RS07850	COG0315	cyclic pyranopterin monophosphate synthase activity
AOX55_RS07855	COG0134	indole-3-glycerol-phosphate synthase activity
AOX55_RS07860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOX55_RS07865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOX55_RS07880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AOX55_RS07885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOX55_RS07900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOX55_RS07905	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AOX55_RS07910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOX55_RS07935	COG0174	glutamine synthetase
AOX55_RS07940	COG0347	Belongs to the P(II) protein family
AOX55_RS07945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOX55_RS07945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AOX55_RS07950	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AOX55_RS07955	COG1058	Belongs to the CinA family
AOX55_RS07955	COG1546	Belongs to the CinA family
AOX55_RS07960	COG0655	NAD(P)H dehydrogenase (quinone) activity
AOX55_RS08005	COG0737	Belongs to the 5'-nucleotidase family
AOX55_RS08010	COG3706	GGDEF domain
AOX55_RS08020	COG0686	Belongs to the AlaDH PNT family
AOX55_RS08035	COG2897	thiosulfate sulfurtransferase activity
AOX55_RS08055	COG4221	oxidoreductase activity
AOX55_RS08065	COG2076	Multidrug Resistance protein
AOX55_RS08390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOX55_RS08425	COG1653	transport
AOX55_RS08445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOX55_RS08465	COG3191	aminopeptidase activity
AOX55_RS08475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOX55_RS08480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOX55_RS08495	COG3608	succinylglutamate desuccinylase aspartoacylase
AOX55_RS08495	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AOX55_RS08500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AOX55_RS08515	COG0513	Belongs to the DEAD box helicase family
AOX55_RS08520	COG0739	heme binding
AOX55_RS08525	COG2833	Protein of unknown function (DUF455)
AOX55_RS08530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOX55_RS08540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOX55_RS08545	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOX55_RS08550	COG3706	GGDEF domain
AOX55_RS08555	COG2945	thiolester hydrolase activity
AOX55_RS08565	COG0719	Fe-S assembly protein
AOX55_RS08570	COG0396	ATPase activity
AOX55_RS08575	COG0719	Fe-S assembly protein
AOX55_RS08580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOX55_RS08585	COG2151	metal-sulfur cluster biosynthetic enzyme
AOX55_RS08590	COG0316	Belongs to the HesB IscA family
AOX55_RS08600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOX55_RS08600	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOX55_RS08605	COG0509	glycine decarboxylation via glycine cleavage system
AOX55_RS08610	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AOX55_RS08645	COG0583	DNA-binding transcription factor activity
AOX55_RS08655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOX55_RS08665	COG4176	ABC-type proline glycine betaine transport system permease component
AOX55_RS08670	COG0517	IMP dehydrogenase activity
AOX55_RS08670	COG4175	Glycine betaine
AOX55_RS08730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOX55_RS08765	COG2267	carboxylic ester hydrolase activity
AOX55_RS08820	COG0784	Response regulator, receiver
AOX55_RS08820	COG4191	Histidine kinase
AOX55_RS08825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOX55_RS08840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOX55_RS08850	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AOX55_RS08855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOX55_RS08870	COG1136	(ABC) transporter
AOX55_RS08875	COG0071	Belongs to the small heat shock protein (HSP20) family
AOX55_RS08895	COG0617	tRNA 3'-terminal CCA addition
AOX55_RS08895	COG0517	IMP dehydrogenase activity
AOX55_RS08895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AOX55_RS08900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOX55_RS08945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOX55_RS08955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOX55_RS08960	COG0629	single-stranded DNA binding
AOX55_RS08965	COG2095	MarC family integral membrane protein
AOX55_RS08970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOX55_RS08980	COG0583	DNA-binding transcription factor activity
AOX55_RS08985	COG0492	ferredoxin-NADP+ reductase activity
AOX55_RS08990	COG1522	sequence-specific DNA binding
AOX55_RS08995	COG0463	Glycosyl transferase, family 2
AOX55_RS09000	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS09005	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS09010	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS09015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOX55_RS09035	COG2321	neutral zinc metallopeptidase
AOX55_RS09040	COG0667	Aldo Keto reductase
AOX55_RS09045	COG0583	DNA-binding transcription factor activity
AOX55_RS09055	COG0534	Mate efflux family protein
AOX55_RS09060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AOX55_RS09075	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AOX55_RS09080	COG0343	queuine tRNA-ribosyltransferase activity
AOX55_RS09090	COG0300	oxidoreductase activity
AOX55_RS09115	COG1388	LysM domain
AOX55_RS09115	COG1376	ErfK ybiS ycfS ynhG family protein
AOX55_RS09140	COG2801	Transposase and inactivated derivatives
AOX55_RS09150	COG0084	hydrolase, TatD family'
AOX55_RS09155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOX55_RS09170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AOX55_RS09180	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOX55_RS09200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AOX55_RS09205	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOX55_RS09210	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AOX55_RS09215	COG0047	phosphoribosylformylglycinamidine synthase activity
AOX55_RS09230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOX55_RS09235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOX55_RS09250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AOX55_RS09260	COG2814	Major facilitator Superfamily
AOX55_RS09265	COG2814	Major facilitator Superfamily
AOX55_RS09270	COG0483	inositol monophosphate 1-phosphatase activity
AOX55_RS09275	COG0037	tRNA processing
AOX55_RS09280	COG2066	Belongs to the glutaminase family
AOX55_RS09285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AOX55_RS09295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOX55_RS09300	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AOX55_RS09305	COG0538	isocitrate dehydrogenase activity
AOX55_RS09310	COG0561	phosphatase activity
AOX55_RS09320	COG0659	secondary active sulfate transmembrane transporter activity
AOX55_RS09325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOX55_RS09330	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AOX55_RS09335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOX55_RS09340	COG2313	pseudouridylate synthase activity
AOX55_RS09360	COG2062	phosphohistidine phosphatase, SixA
AOX55_RS09365	COG3106	COG3106 Predicted ATPase
AOX55_RS09370	COG3768	UPF0283 membrane protein
AOX55_RS09390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOX55_RS09395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOX55_RS09405	COG0633	Ferredoxin
AOX55_RS09420	COG1335	isochorismatase
AOX55_RS09430	COG2857	Cytochrome c1
AOX55_RS09430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOX55_RS09445	COG1132	(ABC) transporter
AOX55_RS09450	COG1132	(ABC) transporter
AOX55_RS09455	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOX55_RS09460	COG2814	Major facilitator Superfamily
AOX55_RS09465	COG0431	NADPH-dependent FMN reductase
AOX55_RS09470	COG0789	Transcriptional regulator
AOX55_RS09480	COG0408	coproporphyrinogen oxidase activity
AOX55_RS09490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOX55_RS09490	COG3218	ABC-type transport auxiliary lipoprotein component
AOX55_RS09500	COG1127	ABC transporter
AOX55_RS09505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOX55_RS09510	COG4948	Mandelate Racemase Muconate Lactonizing
AOX55_RS09525	COG0280	phosphate acetyltransferase
AOX55_RS09525	COG0281	malic enzyme
AOX55_RS09530	COG2197	response regulator
AOX55_RS09545	COG0778	Nitroreductase
AOX55_RS09550	COG0823	Involved in the tonB-independent uptake of proteins
AOX55_RS09560	COG1368	sulfuric ester hydrolase activity
AOX55_RS09575	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AOX55_RS09590	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AOX55_RS09595	COG0546	phosphoglycolate phosphatase activity
AOX55_RS09605	COG0114	fumarate hydratase activity
AOX55_RS09610	COG3706	GGDEF domain
AOX55_RS09625	COG1846	Transcriptional regulator
AOX55_RS09635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOX55_RS09640	COG0840	transmembrane signaling receptor activity
AOX55_RS09650	COG0746	molybdenum cofactor guanylyltransferase activity
AOX55_RS09655	COG1763	Mo-molybdopterin cofactor biosynthetic process
AOX55_RS09685	COG5425	PFAM Usg family protein
AOX55_RS09700	COG3174	membrane
AOX55_RS09705	COG2084	Dehydrogenase
AOX55_RS09715	COG1522	sequence-specific DNA binding
AOX55_RS09720	COG1573	uracil-dna glycosylase
AOX55_RS09740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AOX55_RS09745	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AOX55_RS09750	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AOX55_RS09770	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS09775	COG1129	ABC transporter
AOX55_RS09780	COG1879	ABC-type sugar transport system periplasmic component
AOX55_RS09785	COG1609	Transcriptional regulator
AOX55_RS09790	COG0842	Transport permease protein
AOX55_RS09795	COG1131	(ABC) transporter
AOX55_RS09810	COG0640	Transcriptional regulator
AOX55_RS09815	COG3453	Protein conserved in bacteria
AOX55_RS09815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOX55_RS09820	COG0730	response to heat
AOX55_RS09860	COG0556	nucleotide-excision repair
AOX55_RS09875	COG0484	heat shock protein binding
AOX55_RS09880	COG1278	Cold shock
AOX55_RS09885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOX55_RS09905	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOX55_RS09925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOX55_RS09930	COG1121	(ABC) transporter
AOX55_RS09945	COG3507	Belongs to the glycosyl hydrolase 43 family
AOX55_RS09960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AOX55_RS09965	COG0667	Aldo Keto reductase
AOX55_RS09980	COG3250	beta-galactosidase activity
AOX55_RS09985	COG3842	ATPase activity
AOX55_RS09990	COG0395	ABC-type sugar transport system, permease component
AOX55_RS09995	COG1175	transmembrane transport
AOX55_RS10030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOX55_RS10115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOX55_RS10125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOX55_RS10130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOX55_RS10145	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AOX55_RS10155	COG1797	cobyrinic acid a,c-diamide synthase activity
AOX55_RS10210	COG1492	cobalamin metabolic process
AOX55_RS10230	COG0517	IMP dehydrogenase activity
AOX55_RS10230	COG4175	Glycine betaine
AOX55_RS10245	COG0646	methionine synthase
AOX55_RS10245	COG1410	methionine synthase
AOX55_RS10260	COG2304	oxidoreductase activity
AOX55_RS10275	COG5598	trimethylamine methyltransferase
AOX55_RS10280	COG5012	cobalamin binding
AOX55_RS10330	COG0646	methionine synthase
AOX55_RS10330	COG1410	methionine synthase
AOX55_RS10350	COG1522	sequence-specific DNA binding
AOX55_RS10355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOX55_RS10365	COG1473	amidohydrolase
AOX55_RS10370	COG0583	DNA-binding transcription factor activity
AOX55_RS10395	COG0745	RESPONSE REGULATOR receiver
AOX55_RS10430	COG0861	Integral membrane protein TerC family
AOX55_RS10435	COG3264	Mechanosensitive ion channel
AOX55_RS10435	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AOX55_RS10475	COG0471	metal ion transport
AOX55_RS10475	COG3273	potassium ion transport
AOX55_RS10520	COG4372	Transposase
AOX55_RS10625	COG3791	Glutathione-dependent formaldehyde-activating
AOX55_RS10725	COG0384	phenazine biosynthesis protein PhzF
AOX55_RS10750	COG3791	Glutathione-dependent formaldehyde-activating
AOX55_RS10820	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AOX55_RS10835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOX55_RS10850	COG0561	phosphatase activity
AOX55_RS10855	COG0625	glutathione transferase activity
AOX55_RS10860	COG3842	ATPase activity
AOX55_RS10865	COG4149	molybdate abc transporter
AOX55_RS10870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AOX55_RS10880	COG2894	cell division
AOX55_RS10890	COG0628	permease
AOX55_RS10925	COG0667	Aldo Keto reductase
AOX55_RS10935	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AOX55_RS10935	COG2755	lipolytic protein G-D-S-L family
AOX55_RS10940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOX55_RS10960	COG0667	Aldo Keto reductase
AOX55_RS10965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOX55_RS10975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOX55_RS10980	COG1136	(ABC) transporter
AOX55_RS10980	COG0577	efflux transmembrane transporter activity
AOX55_RS11005	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOX55_RS11010	COG1522	sequence-specific DNA binding
AOX55_RS11015	COG1794	racemase activity, acting on amino acids and derivatives
AOX55_RS11025	COG1733	regulation of RNA biosynthetic process
AOX55_RS11045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOX55_RS11050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AOX55_RS11100	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOX55_RS11100	COG1672	PFAM Archaeal ATPase
AOX55_RS11105	COG1120	ATPase activity
AOX55_RS11110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOX55_RS11115	COG1280	lysine exporter protein (LysE YggA)
AOX55_RS11120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOX55_RS11125	COG3180	Ammonia monooxygenase
AOX55_RS11135	COG1595	DNA-templated transcription, initiation
AOX55_RS11160	COG1090	epimerase
AOX55_RS11185	COG0656	L-ascorbic acid biosynthetic process
AOX55_RS11190	COG3385	transposase activity
AOX55_RS11195	COG0440	acetolactate synthase activity
AOX55_RS11200	COG0028	Belongs to the TPP enzyme family
AOX55_RS11215	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AOX55_RS11220	COG3830	Belongs to the UPF0237 family
AOX55_RS11220	COG0560	Phosphoserine phosphatase
AOX55_RS11255	COG0330	HflC and HflK could
AOX55_RS11275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AOX55_RS11305	COG0277	FAD linked oxidase domain protein
AOX55_RS11320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOX55_RS11375	COG0835	chemotaxis
AOX55_RS11380	COG0840	transmembrane signaling receptor activity
AOX55_RS11395	COG2264	protein methyltransferase activity
AOX55_RS11430	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AOX55_RS11435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AOX55_RS11445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOX55_RS11455	COG0497	DNA recombination
AOX55_RS11460	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOX55_RS11470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOX55_RS11475	COG0849	cell division
AOX55_RS11480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOX55_RS11485	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOX55_RS11495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOX55_RS11500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOX55_RS11505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOX55_RS11515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AOX55_RS11520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOX55_RS11530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOX55_RS11545	COG0275	rRNA processing
AOX55_RS11550	COG2001	Belongs to the MraZ family
AOX55_RS11570	COG3023	N-Acetylmuramoyl-L-alanine amidase
AOX55_RS11575	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AOX55_RS11585	COG1280	lysine exporter protein (LysE YggA)
AOX55_RS11605	COG4106	trans-aconitate 2-methyltransferase activity
AOX55_RS11630	COG2226	methyltransferase
AOX55_RS11640	COG3719	Belongs to the RNase T2 family
AOX55_RS11645	COG2267	carboxylic ester hydrolase activity
AOX55_RS11650	COG0028	Belongs to the TPP enzyme family
AOX55_RS11670	COG1376	ErfK ybiS ycfS ynhG family protein
AOX55_RS11675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS11690	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS11695	COG0174	glutamine synthetase
AOX55_RS11730	COG3842	ATPase activity
AOX55_RS11735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AOX55_RS11745	COG3842	ATPase activity
AOX55_RS11760	COG1177	transmembrane transport
AOX55_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS11780	COG3246	L-lysine catabolic process to acetate
AOX55_RS11785	COG0824	Thioesterase
AOX55_RS11785	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOX55_RS11800	COG1042	CoA-binding domain protein
AOX55_RS11800	COG0045	succinate-CoA ligase (ADP-forming) activity
AOX55_RS11800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOX55_RS11810	COG0747	negative chemotaxis
AOX55_RS11820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS11840	COG0657	acetylesterase activity
AOX55_RS11845	COG0583	DNA-binding transcription factor activity
AOX55_RS11850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AOX55_RS11855	COG3842	ATPase activity
AOX55_RS11860	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOX55_RS11865	COG1177	transmembrane transport
AOX55_RS11870	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS11890	COG4774	siderophore transport
AOX55_RS11910	COG1335	isochorismatase
AOX55_RS11915	COG1522	sequence-specific DNA binding
AOX55_RS11935	COG0583	DNA-binding transcription factor activity
AOX55_RS12020	COG1396	sequence-specific DNA binding
AOX55_RS12025	COG3237	CsbD-like
AOX55_RS12035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOX55_RS12060	COG0649	NAD binding
AOX55_RS12065	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOX55_RS12070	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOX55_RS12090	COG0651	ATP synthesis coupled electron transport
AOX55_RS12100	COG0651	ATP synthesis coupled electron transport
AOX55_RS12105	COG0713	ATP synthesis coupled electron transport
AOX55_RS12145	COG2968	Membrane
AOX55_RS12160	COG0432	Pfam Uncharacterised protein family UPF0047
AOX55_RS12165	COG5507	3-demethylubiquinone-9 3-methyltransferase
AOX55_RS12185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOX55_RS12195	COG1063	alcohol dehydrogenase
AOX55_RS12215	COG0514	ATP-dependent DNA helicase (RecQ)
AOX55_RS12220	COG0358	DNA primase activity
AOX55_RS12230	COG0505	Belongs to the CarA family
AOX55_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS12250	COG0436	Aminotransferase
AOX55_RS12270	COG2133	pyrroloquinoline quinone binding
AOX55_RS12285	COG1278	Cold shock
AOX55_RS12295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOX55_RS12305	COG1846	Transcriptional regulator
AOX55_RS12310	COG0745	RESPONSE REGULATOR receiver
AOX55_RS12315	COG2205	protein histidine kinase activity
AOX55_RS12325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOX55_RS12330	COG0583	DNA-binding transcription factor activity
AOX55_RS12355	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AOX55_RS12365	COG1496	oxidoreductase activity
AOX55_RS12380	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOX55_RS12415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOX55_RS12425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOX55_RS12430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOX55_RS12445	COG4191	Histidine kinase
AOX55_RS12445	COG0784	Response regulator, receiver
AOX55_RS12455	COG3189	MarR family transcriptional regulator
AOX55_RS12460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOX55_RS12490	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS12505	COG3135	benzoate transporter
AOX55_RS12510	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AOX55_RS12515	COG3300	MHYT domain
AOX55_RS12515	COG5001	Diguanylate cyclase
AOX55_RS12525	COG0193	aminoacyl-tRNA hydrolase activity
AOX55_RS12550	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOX55_RS12560	COG2030	dehydratase
AOX55_RS12570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOX55_RS12580	COG0617	tRNA 3'-terminal CCA addition
AOX55_RS12595	COG0714	Associated with various cellular activities
AOX55_RS12625	COG0435	Glutathione S-transferase
AOX55_RS12645	COG0494	nUDIX hydrolase
AOX55_RS12685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOX55_RS12690	COG0740	serine-type endopeptidase activity
AOX55_RS12700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AOX55_RS12705	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AOX55_RS12710	COG0512	Glutamine amidotransferase of anthranilate synthase
AOX55_RS12710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOX55_RS12715	COG1629	transport
AOX55_RS12715	COG4206	TonB-dependent receptor
AOX55_RS12735	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AOX55_RS12775	COG1435	thymidine kinase activity
AOX55_RS12790	COG4175	Glycine betaine
AOX55_RS12805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOX55_RS12810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AOX55_RS12820	COG0366	Alpha amylase catalytic
AOX55_RS12825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOX55_RS12830	COG1160	GTP binding
AOX55_RS12850	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AOX55_RS12860	COG0024	Methionine aminopeptidase
AOX55_RS12885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOX55_RS12890	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS12900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOX55_RS12925	COG0402	S-adenosylhomocysteine deaminase activity
AOX55_RS12935	COG2351	hydroxyisourate hydrolase activity
AOX55_RS12940	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AOX55_RS12965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS12965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOX55_RS12975	COG0513	Belongs to the DEAD box helicase family
AOX55_RS12995	COG2308	Evidence 4 Homologs of previously reported genes of
AOX55_RS13005	COG1305	Transglutaminase-like
AOX55_RS13010	COG0129	dihydroxy-acid dehydratase activity
AOX55_RS13015	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS13025	COG4214	carbohydrate transport
AOX55_RS13035	COG4213	ABC transporter substrate-binding protein
AOX55_RS13055	COG0673	inositol 2-dehydrogenase activity
AOX55_RS13060	COG3300	MHYT domain
AOX55_RS13060	COG5001	Diguanylate cyclase
AOX55_RS13070	COG4213	ABC transporter substrate-binding protein
AOX55_RS13075	COG4214	carbohydrate transport
AOX55_RS13080	COG1129	ABC transporter
AOX55_RS13180	COG3189	MarR family transcriptional regulator
AOX55_RS13185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOX55_RS13195	COG0277	FAD linked oxidase domain protein
AOX55_RS13200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOX55_RS13235	COG2801	Transposase and inactivated derivatives
AOX55_RS13235	COG3415	Transposase
AOX55_RS13240	COG4608	Belongs to the ABC transporter superfamily
AOX55_RS13245	COG0444	Belongs to the ABC transporter superfamily
AOX55_RS13250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS13255	COG0601	transmembrane transport
AOX55_RS13285	COG2346	COG2346, Truncated hemoglobins
AOX55_RS13325	COG3720	iron ion transport
AOX55_RS13330	COG4558	Periplasmic binding protein
AOX55_RS13335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOX55_RS13340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AOX55_RS13355	COG3920	Histidine kinase
AOX55_RS13355	COG2202	Pas domain
AOX55_RS13370	COG0784	Response regulator, receiver
AOX55_RS13380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOX55_RS13385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOX55_RS13410	COG1175	transmembrane transport
AOX55_RS13420	COG2390	Transcriptional regulator
AOX55_RS13425	COG0493	'glutamate synthase
AOX55_RS13440	COG0583	DNA-binding transcription factor activity
AOX55_RS13450	COG1309	transcriptional regulator
AOX55_RS13480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOX55_RS13485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOX55_RS13490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOX55_RS13510	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AOX55_RS13515	COG0830	nickel cation binding
AOX55_RS13520	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AOX55_RS13535	COG0804	urea catabolic process
AOX55_RS13540	COG1442	glycosyl transferase family 8
AOX55_RS13545	COG3755	Protein conserved in bacteria
AOX55_RS13550	COG0832	Belongs to the urease beta subunit family
AOX55_RS13555	COG3813	Protein conserved in bacteria
AOX55_RS13560	COG0831	urea catabolic process
AOX55_RS13565	COG0829	nickel cation binding
AOX55_RS13575	COG1846	Transcriptional regulator
AOX55_RS13580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOX55_RS13585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOX55_RS13600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOX55_RS13630	COG0559	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS13635	COG1218	3'(2'),5'-bisphosphate nucleotidase
AOX55_RS13645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOX55_RS13655	COG0400	carboxylic ester hydrolase activity
AOX55_RS13680	COG0346	lactoylglutathione lyase activity
AOX55_RS13685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOX55_RS13695	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOX55_RS13715	COG0765	amino acid transport
AOX55_RS13760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS13770	COG0626	cystathionine gamma-synthase activity
AOX55_RS13785	COG0395	ABC-type sugar transport system, permease component
AOX55_RS13790	COG3842	ATPase activity
AOX55_RS13800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOX55_RS13805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOX55_RS13810	COG1845	cytochrome c oxidase, subunit III
AOX55_RS13825	COG1959	2 iron, 2 sulfur cluster binding
AOX55_RS13840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOX55_RS13850	COG1116	anion transmembrane transporter activity
AOX55_RS13855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOX55_RS13860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOX55_RS13865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOX55_RS13885	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOX55_RS13900	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AOX55_RS13930	COG2010	Cytochrome c
AOX55_RS13945	COG3278	Belongs to the heme-copper respiratory oxidase family
AOX55_RS13970	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS13980	COG3962	Belongs to the TPP enzyme family
AOX55_RS13985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOX55_RS13990	COG1082	Xylose isomerase domain protein TIM barrel
AOX55_RS13995	COG0673	inositol 2-dehydrogenase activity
AOX55_RS14000	COG0673	inositol 2-dehydrogenase activity
AOX55_RS14005	COG1082	Xylose isomerase domain protein TIM barrel
AOX55_RS14010	COG1129	ABC transporter
AOX55_RS14035	COG1024	Enoyl-CoA hydratase
AOX55_RS14035	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOX55_RS14040	COG1024	Enoyl-CoA hydratase
AOX55_RS14045	COG2050	protein possibly involved in aromatic compounds catabolism
AOX55_RS14060	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS14060	COG2030	dehydratase
AOX55_RS14070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOX55_RS14075	COG2151	metal-sulfur cluster biosynthetic enzyme
AOX55_RS14080	COG3396	Phenylacetate-CoA oxygenase
AOX55_RS14085	COG3460	Phenylacetate-CoA oxygenase
AOX55_RS14090	COG3396	Phenylacetate-CoA oxygenase
AOX55_RS14110	COG2301	Belongs to the HpcH HpaI aldolase family
AOX55_RS14115	COG0045	succinate-CoA ligase (ADP-forming) activity
AOX55_RS14120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AOX55_RS14125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOX55_RS14130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOX55_RS14155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOX55_RS14165	COG4566	intracellular signal transduction
AOX55_RS14170	COG4566	intracellular signal transduction
AOX55_RS14195	COG4191	Histidine kinase
AOX55_RS14200	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOX55_RS14215	COG1877	trehalose-phosphatase activity
AOX55_RS14220	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AOX55_RS14245	COG4372	Transposase
AOX55_RS14250	COG3436	PFAM IS66 Orf2 family protein
AOX55_RS14255	COG2963	transposase activity
AOX55_RS14295	COG0739	heme binding
AOX55_RS14300	COG0542	response to heat
AOX55_RS14315	COG2890	protein-(glutamine-N5) methyltransferase activity
AOX55_RS14320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AOX55_RS14330	COG0527	aspartate kinase activity
AOX55_RS14345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOX55_RS14360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOX55_RS14365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOX55_RS14390	COG0494	nUDIX hydrolase
AOX55_RS14400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOX55_RS14405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOX55_RS14410	COG0653	protein targeting
AOX55_RS14425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOX55_RS14455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOX55_RS14470	COG0300	oxidoreductase activity
AOX55_RS14480	COG2096	Adenosyltransferase
AOX55_RS14490	COG2086	electron transfer activity
AOX55_RS14495	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOX55_RS14500	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOX55_RS14505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOX55_RS14510	COG0165	Argininosuccinate lyase
AOX55_RS14550	COG2884	Cell division ATP-binding protein ftsE
AOX55_RS14570	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AOX55_RS14580	COG0287	Prephenate dehydrogenase
AOX55_RS14590	COG2226	methyltransferase
AOX55_RS14595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOX55_RS14615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AOX55_RS14620	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AOX55_RS14650	COG4536	flavin adenine dinucleotide binding
AOX55_RS14655	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOX55_RS14660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AOX55_RS14670	COG4974	Belongs to the 'phage' integrase family
AOX55_RS14675	COG0825	malonyl-CoA metabolic process
AOX55_RS14680	COG3034	peptidoglycan biosynthetic process
AOX55_RS14685	COG0425	Belongs to the sulfur carrier protein TusA family
AOX55_RS14685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOX55_RS14690	COG2020	methyltransferase activity
AOX55_RS14700	COG0523	cobalamin synthesis protein
AOX55_RS14705	COG1686	Belongs to the peptidase S11 family
AOX55_RS14710	COG1473	amidohydrolase
AOX55_RS14730	COG2207	Transcriptional regulator
AOX55_RS14735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOX55_RS14755	COG4176	ABC-type proline glycine betaine transport system permease component
AOX55_RS14760	COG0517	IMP dehydrogenase activity
AOX55_RS14760	COG4175	Glycine betaine
AOX55_RS14765	COG2986	histidine ammonia-lyase
AOX55_RS14805	COG0656	L-ascorbic acid biosynthetic process
AOX55_RS14840	COG1459	type II secretion system
AOX55_RS14845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOX55_RS14895	COG2072	flavoprotein involved in K transport
AOX55_RS14910	COG0395	ABC-type sugar transport system, permease component
AOX55_RS14915	COG1175	transmembrane transport
AOX55_RS14985	COG0482	sulfurtransferase activity
AOX55_RS15045	COG0564	pseudouridine synthase activity
AOX55_RS15050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOX55_RS15060	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOX55_RS15070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOX55_RS15090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOX55_RS15095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOX55_RS15100	COG0037	tRNA processing
AOX55_RS15110	COG2885	chlorophyll binding
AOX55_RS15115	COG0823	Involved in the tonB-independent uptake of proteins
AOX55_RS15135	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AOX55_RS15145	COG0824	Thioesterase
AOX55_RS15165	COG1408	metallophosphoesterase
AOX55_RS15170	COG2255	four-way junction helicase activity
AOX55_RS15175	COG0632	four-way junction helicase activity
AOX55_RS15185	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AOX55_RS15190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOX55_RS15195	COG0217	transcriptional regulatory protein
AOX55_RS15210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOX55_RS15215	COG1692	metallophosphoesterase
AOX55_RS15230	COG0583	DNA-binding transcription factor activity
AOX55_RS15265	COG0126	phosphoglycerate kinase activity
AOX55_RS15270	COG3588	fructose-bisphosphate aldolase
AOX55_RS15275	COG0384	phenazine biosynthesis protein PhzF
AOX55_RS15305	COG0254	rRNA binding
AOX55_RS15310	COG1132	(ABC) transporter
AOX55_RS15335	COG0483	inositol monophosphate 1-phosphatase activity
AOX55_RS15360	COG0640	Transcriptional regulator
AOX55_RS15375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AOX55_RS15380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AOX55_RS15385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOX55_RS15390	COG0457	Tetratricopeptide repeat
AOX55_RS15400	COG0469	pyruvate kinase activity
AOX55_RS15420	COG3750	Belongs to the UPF0335 family
AOX55_RS15425	COG3108	Peptidase M15
AOX55_RS15430	COG2204	response regulator
AOX55_RS15440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOX55_RS15440	COG0512	Glutamine amidotransferase of anthranilate synthase
AOX55_RS15460	COG5310	Homospermidine synthase
AOX55_RS15470	COG0737	Belongs to the 5'-nucleotidase family
AOX55_RS15475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOX55_RS15515	COG0786	glutamate:sodium symporter activity
AOX55_RS15520	COG0628	permease
AOX55_RS15530	COG3706	GGDEF domain
AOX55_RS15530	COG2203	Gaf domain
AOX55_RS15530	COG5001	Diguanylate cyclase
AOX55_RS15530	COG4251	negative regulation of phosphorylation
AOX55_RS15535	COG0330	HflC and HflK could
AOX55_RS15540	COG1585	Membrane protein implicated in regulation of membrane protease activity
AOX55_RS15560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOX55_RS15565	COG2951	lytic endotransglycosylase activity
AOX55_RS15580	COG0069	glutamate synthase activity
AOX55_RS15580	COG0070	glutamate synthase
AOX55_RS15580	COG0067	glutamate synthase
AOX55_RS15590	COG0071	Belongs to the small heat shock protein (HSP20) family
AOX55_RS15595	COG2267	carboxylic ester hydrolase activity
AOX55_RS15655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS15685	COG0251	oxidation-reduction process
AOX55_RS15690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS15695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOX55_RS15700	COG1522	sequence-specific DNA binding
AOX55_RS15710	COG0460	homoserine dehydrogenase
AOX55_RS15725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOX55_RS15740	COG0583	DNA-binding transcription factor activity
AOX55_RS15755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS15780	COG2423	ornithine cyclodeaminase activity
AOX55_RS15785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOX55_RS15810	COG4598	ABC transporter
AOX55_RS15815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOX55_RS15825	COG1522	sequence-specific DNA binding
AOX55_RS15830	COG1522	sequence-specific DNA binding
AOX55_RS15840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS15845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS15850	COG0601	transmembrane transport
AOX55_RS15865	COG2186	Transcriptional regulator
AOX55_RS15875	COG3395	kinase activity
AOX55_RS15880	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOX55_RS15915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOX55_RS15935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOX55_RS15945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS15975	COG0129	dihydroxy-acid dehydratase activity
AOX55_RS16005	COG0583	DNA-binding transcription factor activity
AOX55_RS16010	COG0667	Aldo Keto reductase
AOX55_RS16035	COG0058	SHG alpha-glucan phosphorylase activity
AOX55_RS16040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AOX55_RS16045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOX55_RS16050	COG0297	glycogen (starch) synthase activity
AOX55_RS16055	COG0033	Phosphoglucomutase
AOX55_RS16060	COG1523	belongs to the glycosyl hydrolase 13 family
AOX55_RS16080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AOX55_RS16080	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOX55_RS16090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS16100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AOX55_RS16150	COG5001	Diguanylate cyclase
AOX55_RS16155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AOX55_RS16160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOX55_RS16165	COG1609	Transcriptional regulator
AOX55_RS16180	COG1846	Transcriptional regulator
AOX55_RS16190	COG0523	cobalamin synthesis protein
AOX55_RS16215	COG1280	lysine exporter protein (LysE YggA)
AOX55_RS16230	COG0583	DNA-binding transcription factor activity
AOX55_RS16240	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AOX55_RS16260	COG0800	Aldolase
AOX55_RS16265	COG2954	triphosphatase activity
AOX55_RS16275	COG1054	Belongs to the UPF0176 family
AOX55_RS16295	COG1464	Belongs to the NlpA lipoprotein family
AOX55_RS16300	COG2011	ABC-type metal ion transport system permease component
AOX55_RS16305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOX55_RS16315	COG0673	inositol 2-dehydrogenase activity
AOX55_RS16325	COG2115	Belongs to the xylose isomerase family
AOX55_RS16330	COG1070	Carbohydrate kinase
AOX55_RS16335	COG1609	Transcriptional regulator
AOX55_RS16370	COG1253	flavin adenine dinucleotide binding
AOX55_RS16375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOX55_RS16380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOX55_RS16390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS16405	COG1793	dna ligase
AOX55_RS16405	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AOX55_RS16415	COG2111	Na H antiporter
AOX55_RS16415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOX55_RS16420	COG1006	Multisubunit Na H antiporter MnhC subunit
AOX55_RS16425	COG0651	ATP synthesis coupled electron transport
AOX55_RS16430	COG1863	multisubunit Na H antiporter MnhE subunit
AOX55_RS16435	COG2212	antiporter activity
AOX55_RS16440	COG1320	monovalent cation:proton antiporter activity
AOX55_RS16485	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AOX55_RS16490	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOX55_RS16495	COG4149	molybdate abc transporter
AOX55_RS16500	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AOX55_RS16505	COG2005	Transcriptional regulator
AOX55_RS16505	COG3585	molybdate ion transport
AOX55_RS16510	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS16550	COG0625	glutathione transferase activity
AOX55_RS16560	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AOX55_RS16580	COG2197	response regulator
AOX55_RS16620	COG5001	Diguanylate cyclase
AOX55_RS16620	COG3300	MHYT domain
AOX55_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS16645	COG3938	Belongs to the proline racemase family
AOX55_RS16650	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS16655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS16660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOX55_RS16665	COG0765	amino acid transport
AOX55_RS16670	COG0765	amino acid transport
AOX55_RS16675	COG1126	abc transporter atp-binding protein
AOX55_RS16710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOX55_RS16715	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS16800	COG1940	carbohydrate kinase activity
AOX55_RS16805	COG4702	Belongs to the UPF0303 family
AOX55_RS16810	COG2942	2-epimerase
AOX55_RS16885	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOX55_RS16890	COG0156	8-amino-7-oxononanoate synthase activity
AOX55_RS16925	COG3920	Histidine kinase
AOX55_RS16935	COG0028	Belongs to the TPP enzyme family
AOX55_RS16940	COG0729	surface antigen
AOX55_RS16965	COG0010	Belongs to the arginase family
AOX55_RS16970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOX55_RS16975	COG0835	chemotaxis
AOX55_RS16990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOX55_RS16995	COG3383	formate dehydrogenase (NAD+) activity
AOX55_RS17015	COG0583	DNA-binding transcription factor activity
AOX55_RS17035	COG3842	ATPase activity
AOX55_RS17040	COG3842	ATPase activity
AOX55_RS17050	COG0395	ABC-type sugar transport system, permease component
AOX55_RS17065	COG2233	PERMEase
AOX55_RS17085	COG1121	(ABC) transporter
AOX55_RS17090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOX55_RS17095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOX55_RS17115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AOX55_RS17125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AOX55_RS17130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AOX55_RS17135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AOX55_RS17140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOX55_RS17155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOX55_RS17160	COG3385	transposase activity
AOX55_RS17170	COG4974	Belongs to the 'phage' integrase family
AOX55_RS17190	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS17205	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOX55_RS17215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AOX55_RS17220	COG0045	succinate-CoA ligase (ADP-forming) activity
AOX55_RS17225	COG0039	L-malate dehydrogenase activity
AOX55_RS17230	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOX55_RS17240	COG2845	Protein of unknown function (DUF459)
AOX55_RS17245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOX55_RS17270	COG2009	succinate dehydrogenase
AOX55_RS17285	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AOX55_RS17300	COG0745	RESPONSE REGULATOR receiver
AOX55_RS17315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AOX55_RS17320	COG1674	ftsk spoiiie
AOX55_RS17325	COG0004	ammonium transporteR
AOX55_RS17330	COG0347	Belongs to the P(II) protein family
AOX55_RS17335	COG1946	Acyl-CoA thioesterase
AOX55_RS17340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOX55_RS17360	COG0066	3-isopropylmalate dehydratase activity
AOX55_RS17365	COG0251	oxidation-reduction process
AOX55_RS17375	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AOX55_RS17405	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AOX55_RS17410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AOX55_RS17425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOX55_RS17430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOX55_RS17435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AOX55_RS17440	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AOX55_RS17445	COG0799	negative regulation of ribosome biogenesis
AOX55_RS17450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AOX55_RS17460	COG0793	Belongs to the peptidase S41A family
AOX55_RS17465	COG2861	carbohydrate metabolic process
AOX55_RS17470	COG0494	nUDIX hydrolase
AOX55_RS17485	COG0587	DNA-directed DNA polymerase activity
AOX55_RS17500	COG2835	tetraacyldisaccharide 4'-kinase activity
AOX55_RS17505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOX55_RS17510	COG3118	belongs to the thioredoxin family
AOX55_RS17540	COG0154	amidase activity
AOX55_RS17550	COG1217	gtp-binding protein TYPA
AOX55_RS17560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AOX55_RS17565	COG1872	DUF167
AOX55_RS17605	COG0181	hydroxymethylbilane synthase activity
AOX55_RS17610	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AOX55_RS17615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AOX55_RS17635	COG0335	large ribosomal subunit rRNA binding
AOX55_RS17640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOX55_RS17645	COG0765	amino acid transport
AOX55_RS17655	COG0336	Belongs to the RNA methyltransferase TrmD family
AOX55_RS17660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOX55_RS17665	COG0228	four-way junction DNA binding
AOX55_RS17670	COG0287	Prephenate dehydrogenase
AOX55_RS17670	COG1605	Chorismate mutase
AOX55_RS17675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOX55_RS17690	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AOX55_RS17695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOX55_RS17705	COG2917	probably involved in intracellular septation
AOX55_RS17725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOX55_RS17730	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOX55_RS17735	COG4133	protoheme IX ABC transporter activity
AOX55_RS17740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOX55_RS17760	COG0670	Belongs to the BI1 family
AOX55_RS17770	COG4181	ATPase activity
AOX55_RS17780	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AOX55_RS17785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOX55_RS17790	COG2154	pterin-4-alpha-carbinolamine dehydratase
AOX55_RS17805	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AOX55_RS17815	COG0137	argininosuccinate synthase activity
AOX55_RS17830	COG0488	(ABC) transporter
AOX55_RS17855	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AOX55_RS17875	COG1329	Transcriptional regulator
AOX55_RS17880	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AOX55_RS17895	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS17900	COG0183	Belongs to the thiolase family
AOX55_RS17905	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AOX55_RS17910	COG3385	transposase activity
AOX55_RS17915	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AOX55_RS17920	COG0625	glutathione transferase activity
AOX55_RS17925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOX55_RS17930	COG0142	geranyltranstransferase activity
AOX55_RS17935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOX55_RS17940	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AOX55_RS17945	COG2223	nitrite transmembrane transporter activity
AOX55_RS17950	COG0346	lactoylglutathione lyase activity
AOX55_RS17955	COG1349	DNA-binding transcription factor activity
AOX55_RS17960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOX55_RS17965	COG0765	amino acid transport
AOX55_RS17970	COG1126	abc transporter atp-binding protein
AOX55_RS17975	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AOX55_RS17995	COG1132	(ABC) transporter
AOX55_RS18010	COG3459	Glycosyltransferase 36 associated
AOX55_RS18025	COG5383	Protein conserved in bacteria
AOX55_RS18035	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS18040	COG0436	Aminotransferase
AOX55_RS18055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOX55_RS18090	COG3842	ATPase activity
AOX55_RS18100	COG1175	transmembrane transport
AOX55_RS18105	COG1653	transport
AOX55_RS18110	COG1609	Transcriptional regulator
AOX55_RS18115	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS18120	COG1024	Enoyl-CoA hydratase
AOX55_RS18130	COG0673	inositol 2-dehydrogenase activity
AOX55_RS18135	COG1609	Transcriptional regulator
AOX55_RS18145	COG0339	signal peptide processing
AOX55_RS18155	COG0473	3-isopropylmalate dehydrogenase activity
AOX55_RS18160	COG0671	phosphoesterase, PA-phosphatase related
AOX55_RS18180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOX55_RS18190	COG0288	reversible hydration of carbon dioxide
AOX55_RS18210	COG0138	bifunctional purine biosynthesis protein purh
AOX55_RS18220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AOX55_RS18220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOX55_RS18225	COG0501	Belongs to the peptidase M48B family
AOX55_RS18235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOX55_RS18245	COG0662	Cupin 2, conserved barrel domain protein
AOX55_RS18250	COG0583	DNA-binding transcription factor activity
AOX55_RS18265	COG0495	leucyl-tRNA aminoacylation
AOX55_RS18290	COG0357	Ribosomal RNA small subunit methyltransferase G
AOX55_RS18295	COG0445	tRNA wobble uridine modification
AOX55_RS18300	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AOX55_RS18305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AOX55_RS18310	COG1981	membrane
AOX55_RS18315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOX55_RS18320	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AOX55_RS18325	COG0424	maF-like protein
AOX55_RS18330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOX55_RS18335	COG0237	dephospho-CoA kinase activity
AOX55_RS18350	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS18355	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AOX55_RS18360	COG3030	protein affecting phage T7 exclusion by the F plasmid
AOX55_RS18405	COG1802	Transcriptional regulator
AOX55_RS18410	COG2721	sulfolactate sulfo-lyase activity
AOX55_RS18430	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS18435	COG1063	alcohol dehydrogenase
AOX55_RS18460	COG0135	phosphoribosylanthranilate isomerase activity
AOX55_RS18465	COG0133	tryptophan synthase activity
AOX55_RS18470	COG0159	tryptophan synthase activity
AOX55_RS18475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AOX55_RS18495	COG2887	Belongs to the helicase family. UvrD subfamily
AOX55_RS18500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOX55_RS18505	COG3178	'Phosphotransferase
AOX55_RS18510	COG2205	protein histidine kinase activity
AOX55_RS18515	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOX55_RS18520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOX55_RS18525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOX55_RS18525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOX55_RS18535	COG2205	protein histidine kinase activity
AOX55_RS18540	COG0745	RESPONSE REGULATOR receiver
AOX55_RS18545	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AOX55_RS18555	COG1652	LysM domain
AOX55_RS18565	COG1072	(Pantothenic acid kinase))
AOX55_RS18570	COG0140	phosphoribosyl-ATP diphosphatase activity
AOX55_RS18575	COG0107	imidazoleglycerol-phosphate synthase activity
AOX55_RS18580	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AOX55_RS18585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOX55_RS18595	COG0131	Imidazoleglycerol-phosphate dehydratase
AOX55_RS18600	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AOX55_RS18610	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AOX55_RS18620	COG2124	cytochrome p450
AOX55_RS18635	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOX55_RS18655	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AOX55_RS18665	COG1643	Atp-dependent helicase
AOX55_RS18670	COG4136	ATPase activity
AOX55_RS18675	COG4135	transport system, permease component
AOX55_RS18680	COG4134	Bacterial extracellular solute-binding protein
AOX55_RS18685	COG2423	ornithine cyclodeaminase activity
AOX55_RS18735	COG1819	glycosyl
AOX55_RS18765	COG3485	protocatechuate 3,4-dioxygenase
AOX55_RS18785	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS18790	COG2814	Major facilitator Superfamily
AOX55_RS18795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOX55_RS18810	COG0471	metal ion transport
AOX55_RS18810	COG3273	potassium ion transport
AOX55_RS18860	COG0628	permease
AOX55_RS18910	COG0436	Aminotransferase
AOX55_RS18920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOX55_RS18950	COG0745	RESPONSE REGULATOR receiver
AOX55_RS18955	COG2205	protein histidine kinase activity
AOX55_RS18955	COG0784	Response regulator, receiver
AOX55_RS18975	COG2217	Heavy metal translocating P-type atpase
AOX55_RS18985	COG3845	ABC transporter
AOX55_RS18990	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS18995	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS19005	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AOX55_RS19010	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AOX55_RS19020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AOX55_RS19025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOX55_RS19030	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AOX55_RS19065	COG4964	Belongs to the GSP D family
AOX55_RS19095	COG4423	Transcription factor
AOX55_RS19100	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
AOX55_RS19110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOX55_RS19120	COG0791	NLP P60 protein
AOX55_RS19130	COG4172	Belongs to the ABC transporter superfamily
AOX55_RS19135	COG4239	(ABC) transporter, permease
AOX55_RS19140	COG4174	ABC transporter (Permease)
AOX55_RS19145	COG4166	transmembrane transport
AOX55_RS19150	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AOX55_RS19155	COG1803	Methylglyoxal synthase
AOX55_RS19160	COG0837	glucose binding
AOX55_RS19165	COG1132	(ABC) transporter
AOX55_RS19170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AOX55_RS19175	COG0588	phosphoglycerate mutase activity
AOX55_RS19195	COG1309	transcriptional regulator
AOX55_RS19205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOX55_RS19235	COG1392	Phosphate transport regulator
AOX55_RS19240	COG0306	phosphate transporter
AOX55_RS19255	COG0484	heat shock protein binding
AOX55_RS19260	COG0443	Heat shock 70 kDa protein
AOX55_RS19265	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOX55_RS19295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOX55_RS19295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOX55_RS19315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOX55_RS19320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOX55_RS19335	COG0673	inositol 2-dehydrogenase activity
AOX55_RS19340	COG0395	ABC-type sugar transport system, permease component
AOX55_RS19345	COG1175	transmembrane transport
AOX55_RS19355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AOX55_RS19360	COG2971	BadF BadG BcrA BcrD
AOX55_RS19365	COG2188	Transcriptional regulator
AOX55_RS19370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOX55_RS19375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AOX55_RS19380	COG3142	Participates in the control of copper homeostasis
AOX55_RS19385	COG1940	carbohydrate kinase activity
AOX55_RS19400	COG2900	Belongs to the SlyX family
AOX55_RS19405	COG1744	ABC transporter substrate-binding protein PnrA-like
AOX55_RS19410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOX55_RS19440	COG1785	Belongs to the alkaline phosphatase family
AOX55_RS19455	COG1396	sequence-specific DNA binding
AOX55_RS19500	COG0488	(ABC) transporter
AOX55_RS19530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOX55_RS19535	COG3474	cytochrome
AOX55_RS19540	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AOX55_RS19545	COG0077	Prephenate dehydratase
AOX55_RS19545	COG1605	Chorismate mutase
AOX55_RS19560	COG2378	regulation of single-species biofilm formation
AOX55_RS19565	COG2816	NAD+ diphosphatase activity
AOX55_RS19580	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOX55_RS19585	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AOX55_RS19595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOX55_RS19600	COG2951	lytic endotransglycosylase activity
AOX55_RS19615	COG2814	Major facilitator Superfamily
AOX55_RS19620	COG0779	Required for maturation of 30S ribosomal subunits
AOX55_RS19625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOX55_RS19625	COG0195	Participates in both transcription termination and antitermination
AOX55_RS19635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AOX55_RS19640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AOX55_RS19645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOX55_RS19655	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AOX55_RS19660	COG1185	polyribonucleotide nucleotidyltransferase activity
AOX55_RS19670	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOX55_RS19680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOX55_RS19690	COG2860	membrane
AOX55_RS19710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOX55_RS19730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AOX55_RS19735	COG0539	negative regulation of cytoplasmic translation
AOX55_RS19760	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOX55_RS19765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOX55_RS19780	COG1238	metal cluster binding
AOX55_RS19820	COG0481	GTPase activity
AOX55_RS19830	COG1396	sequence-specific DNA binding
AOX55_RS19845	COG3932	Exopolysaccharide synthesis, ExoD
AOX55_RS19850	COG2885	chlorophyll binding
AOX55_RS19855	COG1509	lysine 2,3-aminomutase activity
AOX55_RS19860	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AOX55_RS19865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AOX55_RS19870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOX55_RS19890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AOX55_RS19925	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AOX55_RS19930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AOX55_RS19935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AOX55_RS19940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOX55_RS19940	COG0072	phenylalanine-tRNA ligase activity
AOX55_RS19965	COG3685	Protein conserved in bacteria
AOX55_RS19980	COG0667	Aldo Keto reductase
AOX55_RS19990	COG1570	exodeoxyribonuclease VII activity
AOX55_RS19995	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOX55_RS20000	COG1846	Transcriptional regulator
AOX55_RS20005	COG0697	spore germination
AOX55_RS20010	COG2309	aminopeptidase activity
AOX55_RS20015	COG0625	glutathione transferase activity
AOX55_RS20030	COG1393	Belongs to the ArsC family
AOX55_RS20040	COG1448	Aminotransferase
AOX55_RS20045	COG1522	sequence-specific DNA binding
AOX55_RS20055	COG0519	Catalyzes the synthesis of GMP from XMP
AOX55_RS20055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOX55_RS20105	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOX55_RS20115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOX55_RS20125	COG1968	undecaprenyl-diphosphatase activity
AOX55_RS20135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOX55_RS20145	COG0284	orotidine-5'-phosphate decarboxylase activity
AOX55_RS20155	COG3963	phosphatidate phosphatase activity
AOX55_RS20170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AOX55_RS20175	COG0792	nuclease activity
AOX55_RS20190	COG0395	ABC-type sugar transport system, permease component
AOX55_RS20195	COG3842	ATPase activity
AOX55_RS20205	COG0189	ligase activity
AOX55_RS20210	COG0606	chelatase, subunit chli
AOX55_RS20215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOX55_RS20240	COG1522	sequence-specific DNA binding
AOX55_RS20255	COG0756	dUTP diphosphatase activity
AOX55_RS20260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AOX55_RS20280	COG2207	Transcriptional regulator
AOX55_RS20280	COG1917	Cupin 2, conserved barrel domain protein
AOX55_RS20305	COG3718	enzyme involved in inositol metabolism
AOX55_RS20325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOX55_RS20345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOX55_RS20350	COG0590	tRNA wobble adenosine to inosine editing
AOX55_RS20355	COG1881	PFAM PEBP family protein
AOX55_RS20365	COG0456	acetyltransferase
AOX55_RS20370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOX55_RS20375	COG2226	methyltransferase
AOX55_RS20380	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOX55_RS20385	COG1024	Enoyl-CoA hydratase
AOX55_RS20390	COG0268	Binds directly to 16S ribosomal RNA
AOX55_RS20395	COG1192	Involved in chromosome partitioning
AOX55_RS20400	COG1475	DNA binding
AOX55_RS20405	COG1414	Transcriptional regulator
AOX55_RS20430	COG0697	spore germination
AOX55_RS20435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOX55_RS20440	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AOX55_RS20455	COG0583	DNA-binding transcription factor activity
AOX55_RS20460	COG5598	trimethylamine methyltransferase
AOX55_RS20465	COG1902	pentaerythritol trinitrate reductase activity
AOX55_RS20465	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOX55_RS20490	COG4638	Rieske (2fe-2S)
AOX55_RS20495	COG0583	DNA-binding transcription factor activity
AOX55_RS20505	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AOX55_RS20515	COG4176	ABC-type proline glycine betaine transport system permease component
AOX55_RS20525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOX55_RS20535	COG1902	pentaerythritol trinitrate reductase activity
AOX55_RS20535	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOX55_RS20545	COG2086	electron transfer activity
AOX55_RS20555	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AOX55_RS20565	COG0604	alcohol dehydrogenase
AOX55_RS20565	COG3321	synthase
AOX55_RS20565	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS20570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOX55_RS20575	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS20585	COG1522	sequence-specific DNA binding
AOX55_RS20590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOX55_RS20595	COG1126	abc transporter atp-binding protein
AOX55_RS20605	COG0765	amino acid transport
AOX55_RS20610	COG0765	amino acid transport
AOX55_RS20620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOX55_RS20625	COG2423	ornithine cyclodeaminase activity
AOX55_RS20630	COG0006	proline dipeptidase activity
AOX55_RS20635	COG3608	succinylglutamate desuccinylase aspartoacylase
AOX55_RS20655	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOX55_RS20660	COG3360	Dodecin
AOX55_RS20665	COG2814	Major facilitator Superfamily
AOX55_RS20675	COG1609	Transcriptional regulator
AOX55_RS20680	COG1653	transport
AOX55_RS20695	COG3842	ATPase activity
AOX55_RS20735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOX55_RS20750	COG1063	alcohol dehydrogenase
AOX55_RS20755	COG2814	Major facilitator Superfamily
AOX55_RS20760	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS20765	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS20770	COG1454	alcohol dehydrogenase
AOX55_RS20785	COG0583	DNA-binding transcription factor activity
AOX55_RS20795	COG3485	protocatechuate 3,4-dioxygenase
AOX55_RS20810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOX55_RS20815	COG0183	Belongs to the thiolase family
AOX55_RS20840	COG0251	oxidation-reduction process
AOX55_RS20875	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOX55_RS20885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOX55_RS20890	COG1126	abc transporter atp-binding protein
AOX55_RS20895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOX55_RS20900	COG0765	amino acid transport
AOX55_RS20920	COG3485	protocatechuate 3,4-dioxygenase
AOX55_RS20925	COG3971	2-oxopent-4-enoate hydratase activity
AOX55_RS20970	COG1335	isochorismatase
AOX55_RS20980	COG4166	transmembrane transport
AOX55_RS20985	COG0601	transmembrane transport
AOX55_RS20990	COG4171	peptide transport system, permease
AOX55_RS20995	COG4172	Belongs to the ABC transporter superfamily
AOX55_RS21090	COG1082	Xylose isomerase domain protein TIM barrel
AOX55_RS21095	COG0673	inositol 2-dehydrogenase activity
AOX55_RS21105	COG1129	ABC transporter
AOX55_RS21110	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS21115	COG1879	ABC-type sugar transport system periplasmic component
AOX55_RS21125	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS21130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOX55_RS21135	COG2814	Major facilitator Superfamily
AOX55_RS21170	COG1609	Transcriptional regulator
AOX55_RS21180	COG4211	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS21185	COG1129	ABC transporter
AOX55_RS21195	COG0673	inositol 2-dehydrogenase activity
AOX55_RS21225	COG2226	methyltransferase
AOX55_RS21265	COG0583	DNA-binding transcription factor activity
AOX55_RS21270	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS21280	COG2080	2 iron, 2 sulfur cluster binding
AOX55_RS21285	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AOX55_RS21290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOX55_RS21330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOX55_RS21365	COG0400	carboxylic ester hydrolase activity
AOX55_RS21370	COG0346	lactoylglutathione lyase activity
AOX55_RS21375	COG0583	DNA-binding transcription factor activity
AOX55_RS21395	COG4977	sequence-specific DNA binding
AOX55_RS21395	COG1917	Cupin 2, conserved barrel domain protein
AOX55_RS21400	COG1335	isochorismatase
AOX55_RS21410	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOX55_RS21425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AOX55_RS21450	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS21460	COG0667	Aldo Keto reductase
AOX55_RS21465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOX55_RS21475	COG1070	Carbohydrate kinase
AOX55_RS21505	COG4691	Plasmid stability protein
AOX55_RS21510	COG1487	ribonuclease activity
AOX55_RS21550	COG0492	ferredoxin-NADP+ reductase activity
AOX55_RS21560	COG0723	plastoquinol--plastocyanin reductase activity
AOX55_RS21570	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AOX55_RS21595	COG1278	Cold shock
AOX55_RS21605	COG1396	sequence-specific DNA binding
AOX55_RS21680	COG0071	Belongs to the small heat shock protein (HSP20) family
AOX55_RS21685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOX55_RS21695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOX55_RS21765	COG3077	Addiction module antitoxin, RelB DinJ family
AOX55_RS21815	COG3609	addiction module antidote protein, CC2985 family
AOX55_RS22035	COG0784	Response regulator, receiver
AOX55_RS22035	COG4191	Histidine kinase
AOX55_RS22045	COG3189	MarR family transcriptional regulator
AOX55_RS22050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOX55_RS22065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOX55_RS22090	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS22095	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS22100	COG3845	ABC transporter
AOX55_RS22165	COG0456	acetyltransferase
AOX55_RS22165	COG0454	-acetyltransferase
AOX55_RS22170	COG1609	Transcriptional regulator
AOX55_RS22180	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS22185	COG0604	alcohol dehydrogenase
AOX55_RS22195	COG2084	Dehydrogenase
AOX55_RS22200	COG3265	gluconokinase activity
AOX55_RS22205	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS22210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOX55_RS22215	COG1063	alcohol dehydrogenase
AOX55_RS22220	COG3386	PFAM SMP-30 Gluconolaconase
AOX55_RS22240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOX55_RS22250	COG2186	Transcriptional regulator
AOX55_RS22290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOX55_RS22290	COG2010	Cytochrome c
AOX55_RS22300	COG2207	Transcriptional regulator
AOX55_RS22305	COG0287	Prephenate dehydrogenase
AOX55_RS22320	COG1129	ABC transporter
AOX55_RS22325	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS22335	COG0673	inositol 2-dehydrogenase activity
AOX55_RS22355	COG1850	ribulose-bisphosphate carboxylase activity
AOX55_RS22370	COG2204	response regulator
AOX55_RS22375	COG4191	Histidine kinase
AOX55_RS22380	COG1301	dicarboxylic acid transport
AOX55_RS22385	COG0745	RESPONSE REGULATOR receiver
AOX55_RS22390	COG0784	Response regulator, receiver
AOX55_RS22390	COG2198	Histidine kinase
AOX55_RS22390	COG5002	protein histidine kinase activity
AOX55_RS22400	COG0640	Transcriptional regulator
AOX55_RS22425	COG0559	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS22435	COG0411	ABC transporter
AOX55_RS22455	COG1129	ABC transporter
AOX55_RS22460	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS22465	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS22470	COG4948	Mandelate Racemase Muconate Lactonizing
AOX55_RS22475	COG1192	Involved in chromosome partitioning
AOX55_RS22480	COG1475	DNA binding
AOX55_RS22485	COG0673	inositol 2-dehydrogenase activity
AOX55_RS22490	COG1082	Xylose isomerase domain protein TIM barrel
AOX55_RS22495	COG1082	Xylose isomerase domain protein TIM barrel
AOX55_RS22500	COG1609	Transcriptional regulator
AOX55_RS22540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOX55_RS22545	COG0765	amino acid transport
AOX55_RS22550	COG0765	amino acid transport
AOX55_RS22570	COG1595	DNA-templated transcription, initiation
AOX55_RS22575	COG1254	Belongs to the acylphosphatase family
AOX55_RS22585	COG0183	Belongs to the thiolase family
AOX55_RS22590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOX55_RS22595	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOX55_RS22600	COG1414	Transcriptional regulator
AOX55_RS22620	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS22630	COG2022	thiamine diphosphate biosynthetic process
AOX55_RS22645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AOX55_RS22660	COG4221	oxidoreductase activity
AOX55_RS22680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOX55_RS22685	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOX55_RS22690	COG4221	oxidoreductase activity
AOX55_RS22695	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS22700	COG0277	FAD linked oxidase domain protein
AOX55_RS22700	COG0247	lactate metabolic process
AOX55_RS22705	COG2186	Transcriptional regulator
AOX55_RS22710	COG0028	Belongs to the TPP enzyme family
AOX55_RS22715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS22720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOX55_RS22725	COG0436	Aminotransferase
AOX55_RS22810	COG2205	protein histidine kinase activity
AOX55_RS22810	COG2198	Histidine kinase
AOX55_RS22810	COG0784	Response regulator, receiver
AOX55_RS22835	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AOX55_RS22840	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AOX55_RS22845	COG0535	radical SAM domain protein
AOX55_RS22850	COG0535	radical SAM domain protein
AOX55_RS22855	COG2207	Transcriptional regulator
AOX55_RS22855	COG3708	Transcriptional regulator
AOX55_RS22885	COG0425	Belongs to the sulfur carrier protein TusA family
AOX55_RS22925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOX55_RS22935	COG3119	arylsulfatase activity
AOX55_RS22940	COG0745	RESPONSE REGULATOR receiver
AOX55_RS22945	COG4566	intracellular signal transduction
AOX55_RS22955	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOX55_RS22975	COG2197	response regulator
AOX55_RS22980	COG4585	Histidine kinase
AOX55_RS23005	COG0569	domain protein
AOX55_RS23025	COG4585	Histidine kinase
AOX55_RS23050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOX55_RS23050	COG0646	methionine synthase
AOX55_RS23095	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AOX55_RS23100	COG1877	trehalose-phosphatase activity
AOX55_RS23105	COG1396	sequence-specific DNA binding
AOX55_RS23115	COG1522	sequence-specific DNA binding
AOX55_RS23140	COG0583	DNA-binding transcription factor activity
AOX55_RS23155	COG3920	Histidine kinase
AOX55_RS23190	COG3237	CsbD-like
AOX55_RS23200	COG1802	Transcriptional regulator
AOX55_RS23305	COG1846	Transcriptional regulator
AOX55_RS23325	COG1764	response to oxidative stress
AOX55_RS23345	COG3300	MHYT domain
AOX55_RS23345	COG5001	Diguanylate cyclase
AOX55_RS23360	COG1802	Transcriptional regulator
AOX55_RS23365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AOX55_RS23370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AOX55_RS23375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AOX55_RS23380	COG0277	FAD linked oxidase domain protein
AOX55_RS23385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOX55_RS23390	COG1309	transcriptional regulator
AOX55_RS23400	COG1765	OsmC-like protein
AOX55_RS23425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AOX55_RS23425	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOX55_RS23430	COG4311	Sarcosine oxidase, delta subunit
AOX55_RS23435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS23440	COG4977	sequence-specific DNA binding
AOX55_RS23450	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AOX55_RS23455	COG2218	PFAM glutamate synthase alpha subunit domain protein
AOX55_RS23460	COG0069	glutamate synthase activity
AOX55_RS23465	COG0174	glutamine synthetase
AOX55_RS23550	COG2089	acid synthase
AOX55_RS23555	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AOX55_RS23565	COG2226	methyltransferase
AOX55_RS23575	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS23605	COG4372	Transposase
AOX55_RS23625	COG4372	Transposase
AOX55_RS23630	COG3436	PFAM IS66 Orf2 family protein
AOX55_RS23750	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS23755	COG3845	ABC transporter
AOX55_RS23770	COG0625	glutathione transferase activity
AOX55_RS23840	COG4171	peptide transport system, permease
AOX55_RS23845	COG0601	transmembrane transport
AOX55_RS23850	COG4166	transmembrane transport
AOX55_RS23860	COG0583	DNA-binding transcription factor activity
AOX55_RS23865	COG2828	Protein conserved in bacteria
AOX55_RS23880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOX55_RS23890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AOX55_RS23925	COG3838	Conjugal transfer protein Trbc
AOX55_RS23930	COG3702	type iv secretory pathway
AOX55_RS23935	COG3451	type IV secretory pathway VirB4
AOX55_RS23960	COG3736	Type IV secretory pathway, component VirB8
AOX55_RS23965	COG3504	Conjugal transfer protein
AOX55_RS23970	COG2948	multi-organism process
AOX55_RS23975	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AOX55_RS23985	COG4227	nucleotidyltransferase activity
AOX55_RS24015	COG3505	Type IV secretory pathway VirD4
AOX55_RS24040	COG1177	transmembrane transport
AOX55_RS24045	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOX55_RS24050	COG3842	ATPase activity
AOX55_RS24060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AOX55_RS24065	COG0028	Belongs to the TPP enzyme family
AOX55_RS24075	COG0745	RESPONSE REGULATOR receiver
AOX55_RS24080	COG0745	RESPONSE REGULATOR receiver
AOX55_RS24085	COG0156	8-amino-7-oxononanoate synthase activity
AOX55_RS24095	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AOX55_RS24100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOX55_RS24115	COG1522	sequence-specific DNA binding
AOX55_RS24130	COG1278	Cold shock
AOX55_RS24140	COG3239	Fatty acid desaturase
AOX55_RS24205	COG4964	Belongs to the GSP D family
AOX55_RS24240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS24245	COG0601	transmembrane transport
AOX55_RS24265	COG0454	-acetyltransferase
AOX55_RS24275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS24285	COG0625	glutathione transferase activity
AOX55_RS24305	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS24315	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AOX55_RS24340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOX55_RS24355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOX55_RS24365	COG5001	Diguanylate cyclase
AOX55_RS24365	COG4251	negative regulation of phosphorylation
AOX55_RS24365	COG2203	Gaf domain
AOX55_RS24365	COG3706	GGDEF domain
AOX55_RS24380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOX55_RS24390	COG0840	transmembrane signaling receptor activity
AOX55_RS24480	COG0297	glycogen (starch) synthase activity
AOX55_RS24485	COG1881	PFAM PEBP family protein
AOX55_RS24490	COG0753	catalase activity
AOX55_RS24500	COG2094	Belongs to the DNA glycosylase MPG family
AOX55_RS24540	COG1573	uracil-dna glycosylase
AOX55_RS24545	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AOX55_RS24585	COG2226	methyltransferase
AOX55_RS24600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOX55_RS24605	COG1120	ATPase activity
AOX55_RS24610	COG3842	ATPase activity
AOX55_RS24620	COG0395	ABC-type sugar transport system, permease component
AOX55_RS24625	COG1175	transmembrane transport
AOX55_RS24630	COG1653	transport
AOX55_RS24635	COG1609	Transcriptional regulator
AOX55_RS24675	COG0243	molybdopterin cofactor binding
AOX55_RS24685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOX55_RS24690	COG1116	anion transmembrane transporter activity
AOX55_RS24695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOX55_RS24700	COG3707	response regulator
AOX55_RS24710	COG0022	dehydrogenase e1 component
AOX55_RS24715	COG1522	sequence-specific DNA binding
AOX55_RS24730	COG1396	sequence-specific DNA binding
AOX55_RS24755	COG1129	ABC transporter
AOX55_RS24760	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS24780	COG0235	Class ii aldolase
AOX55_RS24790	COG1960	acyl-CoA dehydrogenase activity
AOX55_RS24795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOX55_RS24815	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOX55_RS24830	COG0277	FAD linked oxidase domain protein
AOX55_RS24835	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOX55_RS24840	COG4208	sulfate ABC transporter
AOX55_RS24850	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AOX55_RS24865	COG0765	amino acid transport
AOX55_RS24870	COG0765	amino acid transport
AOX55_RS24880	COG0251	oxidation-reduction process
AOX55_RS24890	COG3842	ATPase activity
AOX55_RS24895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOX55_RS24915	COG1653	transport
AOX55_RS24920	COG1846	Transcriptional regulator
AOX55_RS24920	COG1940	carbohydrate kinase activity
AOX55_RS24940	COG0367	asparagine synthase
AOX55_RS24950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AOX55_RS25005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOX55_RS25010	COG4999	Histidine kinase
AOX55_RS25010	COG3850	Histidine kinase
AOX55_RS25010	COG3437	response regulator, receiver
AOX55_RS25010	COG2205	protein histidine kinase activity
AOX55_RS25035	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS25050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOX55_RS25050	COG0785	Cytochrome C biogenesis protein
AOX55_RS25060	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS25095	COG0596	Alpha beta hydrolase
AOX55_RS25130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOX55_RS25140	COG1959	2 iron, 2 sulfur cluster binding
AOX55_RS25165	COG1404	Belongs to the peptidase S8 family
AOX55_RS25200	COG4999	Histidine kinase
AOX55_RS25200	COG3850	Histidine kinase
AOX55_RS25200	COG3437	response regulator, receiver
AOX55_RS25200	COG2205	protein histidine kinase activity
AOX55_RS25230	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AOX55_RS25235	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOX55_RS25310	COG1116	anion transmembrane transporter activity
AOX55_RS25325	COG3791	Glutathione-dependent formaldehyde-activating
AOX55_RS25345	COG4451	ribulose bisphosphate carboxylase, small
AOX55_RS25355	COG0191	fructose-bisphosphate aldolase activity
AOX55_RS25370	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AOX55_RS25375	COG0583	DNA-binding transcription factor activity
AOX55_RS25385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AOX55_RS25390	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AOX55_RS25395	COG0535	radical SAM domain protein
AOX55_RS25400	COG0535	radical SAM domain protein
AOX55_RS25415	COG0559	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS25445	COG2192	nodulation
AOX55_RS25465	COG2197	response regulator
AOX55_RS25475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AOX55_RS25485	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS25520	COG1596	polysaccharide export
AOX55_RS25525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOX55_RS25535	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOX55_RS25550	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS25555	COG0668	transmembrane transport
AOX55_RS25570	COG1234	tRNA 3'-trailer cleavage
AOX55_RS25600	COG0747	negative chemotaxis
AOX55_RS25605	COG0601	transmembrane transport
AOX55_RS25610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS25620	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS25640	COG1132	(ABC) transporter
AOX55_RS25645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOX55_RS25675	COG2390	Transcriptional regulator
AOX55_RS25685	COG3958	Transketolase
AOX55_RS25690	COG3959	Transketolase, thiamine diphosphate binding domain
AOX55_RS25695	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS25700	COG1879	ABC-type sugar transport system periplasmic component
AOX55_RS25705	COG1129	ABC transporter
AOX55_RS25710	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS25715	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS25720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOX55_RS25735	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AOX55_RS25740	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AOX55_RS25745	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AOX55_RS25750	COG2205	protein histidine kinase activity
AOX55_RS25755	COG0745	RESPONSE REGULATOR receiver
AOX55_RS25760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOX55_RS25770	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AOX55_RS25775	COG0583	DNA-binding transcription factor activity
AOX55_RS25795	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AOX55_RS25810	COG0683	leucine binding
AOX55_RS25820	COG0559	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS25825	COG0411	ABC transporter
AOX55_RS25835	COG2252	PERMEase
AOX55_RS25840	COG3648	Uricase
AOX55_RS25840	COG3195	allantoin biosynthetic process
AOX55_RS25845	COG2351	hydroxyisourate hydrolase activity
AOX55_RS25855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOX55_RS25870	COG0583	DNA-binding transcription factor activity
AOX55_RS25885	COG4953	penicillin-binding protein 1C
AOX55_RS25890	COG2373	Large extracellular alpha-helical protein
AOX55_RS25900	COG0395	ABC-type sugar transport system, permease component
AOX55_RS25915	COG3842	ATPase activity
AOX55_RS25925	COG1349	DNA-binding transcription factor activity
AOX55_RS25930	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AOX55_RS25935	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS25945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOX55_RS25950	COG1175	transmembrane transport
AOX55_RS25955	COG0395	ABC-type sugar transport system, permease component
AOX55_RS25965	COG3842	ATPase activity
AOX55_RS25980	COG0730	response to heat
AOX55_RS25995	COG1732	Glycine betaine
AOX55_RS26000	COG1174	glycine betaine transport
AOX55_RS26005	COG1125	glycine betaine transport
AOX55_RS26010	COG1174	glycine betaine transport
AOX55_RS26025	COG0673	inositol 2-dehydrogenase activity
AOX55_RS26035	COG0395	ABC-type sugar transport system, permease component
AOX55_RS26045	COG3842	ATPase activity
AOX55_RS26055	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS26070	COG0583	DNA-binding transcription factor activity
AOX55_RS26090	COG1737	Transcriptional regulator
AOX55_RS26095	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS26115	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AOX55_RS26125	COG2986	histidine ammonia-lyase
AOX55_RS26130	COG1228	amidohydrolase
AOX55_RS26135	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AOX55_RS26140	COG3454	Phosphonate metabolism
AOX55_RS26145	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AOX55_RS26150	COG3639	organic phosphonate transmembrane transporter activity
AOX55_RS26155	COG3639	organic phosphonate transmembrane transporter activity
AOX55_RS26165	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AOX55_RS26170	COG1960	acyl-CoA dehydrogenase activity
AOX55_RS26195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOX55_RS26205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOX55_RS26210	COG2942	2-epimerase
AOX55_RS26215	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AOX55_RS26230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOX55_RS26245	COG5039	Polysaccharide pyruvyl transferase
AOX55_RS26250	COG0326	Molecular chaperone. Has ATPase activity
AOX55_RS26265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOX55_RS26270	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOX55_RS26275	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS26280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOX55_RS26290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AOX55_RS26290	COG2755	lipolytic protein G-D-S-L family
AOX55_RS26295	COG1216	Glycosyl transferase, family 2
AOX55_RS26300	COG0463	Glycosyl transferase, family 2
AOX55_RS26305	COG1132	(ABC) transporter
AOX55_RS26315	COG4166	transmembrane transport
AOX55_RS26320	COG0601	transmembrane transport
AOX55_RS26325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS26330	COG4172	Belongs to the ABC transporter superfamily
AOX55_RS26335	COG0489	protein tyrosine kinase activity
AOX55_RS26340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOX55_RS26345	COG1596	polysaccharide export
AOX55_RS26355	COG0297	glycogen (starch) synthase activity
AOX55_RS26370	COG2197	response regulator
AOX55_RS26375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOX55_RS26395	COG0346	lactoylglutathione lyase activity
AOX55_RS26405	COG0842	Transport permease protein
AOX55_RS26410	COG0842	Transport permease protein
AOX55_RS26415	COG1131	(ABC) transporter
AOX55_RS26420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOX55_RS26445	COG2194	sulfuric ester hydrolase activity
AOX55_RS26455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOX55_RS26460	COG4302	ethanolamine ammonia-lyase activity
AOX55_RS26465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOX55_RS26475	COG0210	DNA helicase
AOX55_RS26515	COG0579	oxidoreductase
AOX55_RS26525	COG0583	DNA-binding transcription factor activity
AOX55_RS26535	COG1177	transmembrane transport
AOX55_RS26545	COG3842	ATPase activity
AOX55_RS26550	COG4948	Mandelate Racemase Muconate Lactonizing
AOX55_RS26555	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS26565	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS26570	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AOX55_RS26740	COG1047	Peptidyl-prolyl cis-trans
AOX55_RS26745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOX55_RS26765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOX55_RS26765	COG2010	Cytochrome c
AOX55_RS26770	COG2080	2 iron, 2 sulfur cluster binding
AOX55_RS26775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOX55_RS26775	COG2010	Cytochrome c
AOX55_RS26795	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOX55_RS26825	COG3158	transport of potassium into the cell
AOX55_RS26860	COG2801	Transposase and inactivated derivatives
AOX55_RS26865	COG2826	transposase and inactivated derivatives, IS30 family
AOX55_RS26875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOX55_RS26885	COG1116	anion transmembrane transporter activity
AOX55_RS26895	COG1609	Transcriptional regulator
AOX55_RS26900	COG1840	ABC-type Fe3 transport system, periplasmic component
AOX55_RS26910	COG3842	ATPase activity
AOX55_RS26920	COG1522	sequence-specific DNA binding
AOX55_RS26930	COG3842	ATPase activity
AOX55_RS26935	COG0395	ABC-type sugar transport system, permease component
AOX55_RS26940	COG1175	transmembrane transport
AOX55_RS26945	COG1653	transport
AOX55_RS26955	COG1295	ribonuclease BN
AOX55_RS27000	COG0628	permease
AOX55_RS27020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOX55_RS27025	COG4172	Belongs to the ABC transporter superfamily
AOX55_RS27030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS27035	COG0601	transmembrane transport
AOX55_RS27060	COG0189	ligase activity
AOX55_RS27070	COG1879	ABC-type sugar transport system periplasmic component
AOX55_RS27075	COG1129	ABC transporter
AOX55_RS27080	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS27085	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS27090	COG2186	Transcriptional regulator
AOX55_RS27105	COG1175	transmembrane transport
AOX55_RS27110	COG1653	transport
AOX55_RS27120	COG0673	inositol 2-dehydrogenase activity
AOX55_RS27125	COG1609	Transcriptional regulator
AOX55_RS27140	COG3409	Peptidoglycan-binding domain 1 protein
AOX55_RS27140	COG0793	Belongs to the peptidase S41A family
AOX55_RS27150	COG1129	ABC transporter
AOX55_RS27155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOX55_RS27165	COG2273	Hydrolase Family 16
AOX55_RS27165	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AOX55_RS27170	COG3920	Histidine kinase
AOX55_RS27170	COG2202	Pas domain
AOX55_RS27180	COG4608	Belongs to the ABC transporter superfamily
AOX55_RS27185	COG0444	Belongs to the ABC transporter superfamily
AOX55_RS27190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS27195	COG0601	transmembrane transport
AOX55_RS27200	COG0747	negative chemotaxis
AOX55_RS27205	COG2186	Transcriptional regulator
AOX55_RS27210	COG1312	Catalyzes the dehydration of D-mannonate
AOX55_RS27225	COG3842	ATPase activity
AOX55_RS27230	COG0395	ABC-type sugar transport system, permease component
AOX55_RS27250	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS27255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOX55_RS27265	COG2267	carboxylic ester hydrolase activity
AOX55_RS27280	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AOX55_RS27300	COG1609	Transcriptional regulator
AOX55_RS27320	COG0402	S-adenosylhomocysteine deaminase activity
AOX55_RS27325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOX55_RS27330	COG1454	alcohol dehydrogenase
AOX55_RS27340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOX55_RS27345	COG0747	negative chemotaxis
AOX55_RS27350	COG0601	transmembrane transport
AOX55_RS27355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS27360	COG0444	Belongs to the ABC transporter superfamily
AOX55_RS27365	COG4608	Belongs to the ABC transporter superfamily
AOX55_RS27410	COG0392	lysyltransferase activity
AOX55_RS27440	COG0698	ribose 5-phosphate isomerase
AOX55_RS27445	COG0149	triose-phosphate isomerase activity
AOX55_RS27450	COG1349	DNA-binding transcription factor activity
AOX55_RS27465	COG1070	Carbohydrate kinase
AOX55_RS27480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOX55_RS27490	COG3842	ATPase activity
AOX55_RS27495	COG3842	ATPase activity
AOX55_RS27505	COG1175	transmembrane transport
AOX55_RS27510	COG1653	transport
AOX55_RS27535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AOX55_RS27545	COG1278	Cold shock
AOX55_RS27555	COG4521	taurine ABC transporter
AOX55_RS27565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOX55_RS27575	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS27580	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AOX55_RS27595	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AOX55_RS27605	COG3842	ATPase activity
AOX55_RS27610	COG1175	transmembrane transport
AOX55_RS27615	COG0395	ABC-type sugar transport system, permease component
AOX55_RS27620	COG1609	Transcriptional regulator
AOX55_RS27640	COG5001	Diguanylate cyclase
AOX55_RS27650	COG2226	methyltransferase
AOX55_RS27710	COG0673	inositol 2-dehydrogenase activity
AOX55_RS27730	COG0673	inositol 2-dehydrogenase activity
AOX55_RS27735	COG1309	transcriptional regulator
AOX55_RS27740	COG1653	transport
AOX55_RS27745	COG1175	transmembrane transport
AOX55_RS27750	COG0395	ABC-type sugar transport system, permease component
AOX55_RS27755	COG0673	inositol 2-dehydrogenase activity
AOX55_RS27765	COG3842	ATPase activity
AOX55_RS27825	COG0840	transmembrane signaling receptor activity
AOX55_RS27830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOX55_RS27850	COG0602	queuosine metabolic process
AOX55_RS27855	COG0720	synthase
AOX55_RS27865	COG5265	(ABC) transporter
AOX55_RS27870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOX55_RS27875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AOX55_RS27880	COG3307	-O-antigen
AOX55_RS27885	COG1596	polysaccharide export
AOX55_RS27900	COG1215	transferase activity, transferring glycosyl groups
AOX55_RS27920	COG2273	Hydrolase Family 16
AOX55_RS27925	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS27930	COG1215	transferase activity, transferring glycosyl groups
AOX55_RS27935	COG1215	transferase activity, transferring glycosyl groups
AOX55_RS27940	COG1215	transferase activity, transferring glycosyl groups
AOX55_RS27945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOX55_RS27950	COG3206	protein involved in exopolysaccharide biosynthesis
AOX55_RS27950	COG0489	protein tyrosine kinase activity
AOX55_RS27955	COG0351	phosphomethylpyrimidine kinase
AOX55_RS27960	COG0450	alkyl hydroperoxide reductase
AOX55_RS27985	COG0840	transmembrane signaling receptor activity
AOX55_RS27995	COG2197	response regulator
AOX55_RS28000	COG2197	response regulator
AOX55_RS28005	COG2197	response regulator
AOX55_RS28050	COG0395	ABC-type sugar transport system, permease component
AOX55_RS28055	COG1175	transmembrane transport
AOX55_RS28060	COG1653	transport
AOX55_RS28065	COG1609	Transcriptional regulator
AOX55_RS28115	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS28130	COG0517	IMP dehydrogenase activity
AOX55_RS28160	COG1253	flavin adenine dinucleotide binding
AOX55_RS28165	COG0477	Major facilitator Superfamily
AOX55_RS28175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOX55_RS28180	COG1845	cytochrome c oxidase, subunit III
AOX55_RS28185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AOX55_RS28230	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AOX55_RS28255	COG1396	sequence-specific DNA binding
AOX55_RS28290	COG0840	transmembrane signaling receptor activity
AOX55_RS28315	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS28320	COG0297	glycogen (starch) synthase activity
AOX55_RS28350	COG2890	protein-(glutamine-N5) methyltransferase activity
AOX55_RS28360	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AOX55_RS28365	COG2894	cell division
AOX55_RS28370	COG0850	regulation of cytokinetic process
AOX55_RS28375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOX55_RS28380	COG0318	PFAM AMP-dependent synthetase and ligase
AOX55_RS28390	COG0367	asparagine synthase
AOX55_RS28405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOX55_RS28410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOX55_RS28415	COG1312	Catalyzes the dehydration of D-mannonate
AOX55_RS28420	COG1063	alcohol dehydrogenase
AOX55_RS28425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AOX55_RS28435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AOX55_RS28445	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS28450	COG0531	amino acid
AOX55_RS28455	COG1414	Transcriptional regulator
AOX55_RS28460	COG5441	Belongs to the UPF0261 family
AOX55_RS28475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOX55_RS28495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOX55_RS28520	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOX55_RS28525	COG3971	2-oxopent-4-enoate hydratase activity
AOX55_RS28535	COG1846	Transcriptional regulator
AOX55_RS28560	COG0395	ABC-type sugar transport system, permease component
AOX55_RS28565	COG1175	transmembrane transport
AOX55_RS28575	COG3842	ATPase activity
AOX55_RS28585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOX55_RS28590	COG2186	Transcriptional regulator
AOX55_RS28595	COG0235	Class ii aldolase
AOX55_RS28600	COG1609	Transcriptional regulator
AOX55_RS28605	COG2271	Major facilitator Superfamily
AOX55_RS28610	COG2084	Dehydrogenase
AOX55_RS28615	COG3622	Belongs to the hyi family
AOX55_RS28620	COG3395	kinase activity
AOX55_RS28630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AOX55_RS28640	COG2084	Dehydrogenase
AOX55_RS28645	COG3622	Belongs to the hyi family
AOX55_RS28650	COG3960	tartronate-semialdehyde synthase activity
AOX55_RS28655	COG1414	Transcriptional regulator
AOX55_RS28660	COG0583	DNA-binding transcription factor activity
AOX55_RS28665	COG1301	dicarboxylic acid transport
AOX55_RS28670	COG3257	ureidoglycine aminohydrolase activity
AOX55_RS28680	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AOX55_RS28705	COG2084	Dehydrogenase
AOX55_RS28725	COG1129	ABC transporter
AOX55_RS28730	COG4211	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS28775	COG0174	glutamine synthetase
AOX55_RS28790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOX55_RS28800	COG3842	ATPase activity
AOX55_RS28805	COG0395	ABC-type sugar transport system, permease component
AOX55_RS28820	COG1215	transferase activity, transferring glycosyl groups
AOX55_RS28830	COG0246	Mannitol dehydrogenase
AOX55_RS28845	COG1129	ABC transporter
AOX55_RS28850	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS28870	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS28885	COG1024	Enoyl-CoA hydratase
AOX55_RS28890	COG1960	acyl-CoA dehydrogenase activity
AOX55_RS28895	COG3800	Transcriptional regulator
AOX55_RS28895	COG1396	sequence-specific DNA binding
AOX55_RS28900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOX55_RS28910	COG4770	biotin carboxylase activity
AOX55_RS28920	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AOX55_RS28920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AOX55_RS28930	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AOX55_RS28960	COG2188	Transcriptional regulator
AOX55_RS28965	COG3624	Phosphonate C-P lyase system protein PhnG
AOX55_RS28970	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AOX55_RS28975	COG3626	phosphonate metabolism
AOX55_RS28980	COG3627	carbon phosphorus lyase activity
AOX55_RS28985	COG4107	phosphonate C-P lyase system protein PhnK
AOX55_RS28990	COG4778	phosphonate C-P lyase system protein PhnL
AOX55_RS29000	COG2376	Dihydroxyacetone kinase
AOX55_RS29025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOX55_RS29030	COG1802	Transcriptional regulator
AOX55_RS29065	COG3485	protocatechuate 3,4-dioxygenase
AOX55_RS29070	COG3485	protocatechuate 3,4-dioxygenase
AOX55_RS29075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOX55_RS29080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOX55_RS29085	COG0583	DNA-binding transcription factor activity
AOX55_RS29095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AOX55_RS29105	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS29145	COG3938	Belongs to the proline racemase family
AOX55_RS29150	COG4176	ABC-type proline glycine betaine transport system permease component
AOX55_RS29155	COG4176	ABC-type proline glycine betaine transport system permease component
AOX55_RS29160	COG4175	Glycine betaine
AOX55_RS29160	COG3448	diguanylate cyclase activity
AOX55_RS29170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOX55_RS29175	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS29180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOX55_RS29210	COG1802	Transcriptional regulator
AOX55_RS29220	COG0318	PFAM AMP-dependent synthetase and ligase
AOX55_RS29235	COG1486	melibiose metabolic process
AOX55_RS29240	COG4172	Belongs to the ABC transporter superfamily
AOX55_RS29245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS29250	COG0601	transmembrane transport
AOX55_RS29255	COG0747	negative chemotaxis
AOX55_RS29260	COG1486	melibiose metabolic process
AOX55_RS29270	COG1609	Transcriptional regulator
AOX55_RS29280	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
AOX55_RS29320	COG2442	InterPro IPR007367
AOX55_RS29345	COG2154	pterin-4-alpha-carbinolamine dehydratase
AOX55_RS29355	COG0071	Belongs to the small heat shock protein (HSP20) family
AOX55_RS29395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOX55_RS29430	COG2376	Dihydroxyacetone kinase
AOX55_RS29455	COG1461	Dihydroxyacetone kinase
AOX55_RS29465	COG3842	ATPase activity
AOX55_RS29480	COG0395	ABC-type sugar transport system, permease component
AOX55_RS29485	COG1175	transmembrane transport
AOX55_RS29490	COG1840	ABC-type Fe3 transport system, periplasmic component
AOX55_RS29505	COG1116	anion transmembrane transporter activity
AOX55_RS29510	COG0010	Belongs to the arginase family
AOX55_RS29530	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOX55_RS29530	COG1672	PFAM Archaeal ATPase
AOX55_RS29550	COG1252	NADH dehydrogenase
AOX55_RS29565	COG3220	belongs to the UPF0276 family
AOX55_RS29580	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS29585	COG0583	DNA-binding transcription factor activity
AOX55_RS29610	COG4106	trans-aconitate 2-methyltransferase activity
AOX55_RS29635	COG3220	belongs to the UPF0276 family
AOX55_RS29690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOX55_RS29695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOX55_RS29735	COG0459	protein refolding
AOX55_RS29745	COG1999	signal sequence binding
AOX55_RS29765	COG3278	Belongs to the heme-copper respiratory oxidase family
AOX55_RS29795	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOX55_RS29835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOX55_RS29840	COG1396	sequence-specific DNA binding
AOX55_RS29865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AOX55_RS29870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AOX55_RS29875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AOX55_RS29880	COG3958	Transketolase
AOX55_RS29885	COG3959	Transketolase, thiamine diphosphate binding domain
AOX55_RS29890	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS29895	COG0583	DNA-binding transcription factor activity
AOX55_RS29920	COG3300	MHYT domain
AOX55_RS29920	COG5001	Diguanylate cyclase
AOX55_RS29930	COG0523	cobalamin synthesis protein
AOX55_RS30015	COG2244	polysaccharide biosynthetic process
AOX55_RS30050	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOX55_RS30050	COG1672	PFAM Archaeal ATPase
AOX55_RS30060	COG3237	CsbD-like
AOX55_RS30105	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AOX55_RS30110	COG1126	abc transporter atp-binding protein
AOX55_RS30115	COG0765	amino acid transport
AOX55_RS30120	COG4597	amino acid ABC transporter
AOX55_RS30125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOX55_RS30140	COG1621	beta-fructofuranosidase activity
AOX55_RS30145	COG1858	cytochrome C peroxidase
AOX55_RS30170	COG0444	Belongs to the ABC transporter superfamily
AOX55_RS30175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOX55_RS30180	COG0601	transmembrane transport
AOX55_RS30185	COG0747	negative chemotaxis
AOX55_RS30190	COG0626	cystathionine gamma-synthase activity
AOX55_RS30195	COG0583	DNA-binding transcription factor activity
AOX55_RS30210	COG1215	transferase activity, transferring glycosyl groups
AOX55_RS30215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOX55_RS30220	COG2423	ornithine cyclodeaminase activity
AOX55_RS30225	COG3616	Alanine racemase, N-terminal domain
AOX55_RS30230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOX55_RS30235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOX55_RS30240	COG1414	Transcriptional regulator
AOX55_RS30245	COG0247	lactate metabolic process
AOX55_RS30250	COG0277	FAD linked oxidase domain protein
AOX55_RS30255	COG0277	FAD linked oxidase domain protein
AOX55_RS30260	COG4770	biotin carboxylase activity
AOX55_RS30265	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AOX55_RS30270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AOX55_RS30275	COG1129	ABC transporter
AOX55_RS30280	COG1609	Transcriptional regulator
AOX55_RS30285	COG1609	Transcriptional regulator
AOX55_RS30290	COG0673	inositol 2-dehydrogenase activity
AOX55_RS30325	COG4336	lyase activity
AOX55_RS30345	COG0022	dehydrogenase e1 component
AOX55_RS30350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOX55_RS30355	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS30365	COG1082	Xylose isomerase domain protein TIM barrel
AOX55_RS30390	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS30400	COG0022	dehydrogenase e1 component
AOX55_RS30405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOX55_RS30415	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS30425	COG3842	ATPase activity
AOX55_RS30450	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOX55_RS30465	COG0559	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS30485	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS30510	COG1522	sequence-specific DNA binding
AOX55_RS30535	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS30540	COG0438	transferase activity, transferring glycosyl groups
AOX55_RS30580	COG3685	Protein conserved in bacteria
AOX55_RS30585	COG0492	ferredoxin-NADP+ reductase activity
AOX55_RS30655	COG2814	Major facilitator Superfamily
AOX55_RS30660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOX55_RS30660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOX55_RS30665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOX55_RS30675	COG2226	methyltransferase
AOX55_RS30685	COG0475	glutathione-regulated potassium exporter activity
AOX55_RS30685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOX55_RS30705	COG1609	Transcriptional regulator
AOX55_RS30710	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOX55_RS30725	COG0583	DNA-binding transcription factor activity
AOX55_RS30745	COG1120	ATPase activity
AOX55_RS30750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOX55_RS30760	COG1780	Probably involved in ribonucleotide reductase function
AOX55_RS30765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOX55_RS30775	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AOX55_RS30800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOX55_RS30810	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AOX55_RS30825	COG0163	prenyltransferase activity
AOX55_RS30875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOX55_RS30880	COG3180	Ammonia monooxygenase
AOX55_RS30920	COG0583	DNA-binding transcription factor activity
AOX55_RS30925	COG0431	NADPH-dependent FMN reductase
AOX55_RS30980	COG0511	ligase activity, forming carbon-carbon bonds
AOX55_RS30985	COG0439	Biotin carboxylase
AOX55_RS30995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AOX55_RS31000	COG1984	allophanate hydrolase subunit 2
AOX55_RS31005	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AOX55_RS31010	COG0436	Aminotransferase
AOX55_RS31020	COG4221	oxidoreductase activity
AOX55_RS31030	COG0765	amino acid transport
AOX55_RS31035	COG1126	abc transporter atp-binding protein
AOX55_RS31040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOX55_RS31045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOX55_RS31050	COG4106	trans-aconitate 2-methyltransferase activity
AOX55_RS31055	COG1917	Cupin 2, conserved barrel domain protein
AOX55_RS31055	COG2169	Transcriptional regulator
AOX55_RS31105	COG0387	Pfam Sodium calcium exchanger
AOX55_RS31145	COG0405	Gamma-glutamyltransferase
AOX55_RS31175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOX55_RS31185	COG1309	transcriptional regulator
AOX55_RS31190	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AOX55_RS31195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AOX55_RS31200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AOX55_RS31205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOX55_RS31210	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AOX55_RS31210	COG1082	Xylose isomerase domain protein TIM barrel
AOX55_RS31225	COG1511	domain protein
AOX55_RS31225	COG3264	Mechanosensitive ion channel
AOX55_RS31240	COG1279	arginine transmembrane transporter activity
AOX55_RS31245	COG0583	DNA-binding transcription factor activity
AOX55_RS31260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOX55_RS31280	COG1475	DNA binding
AOX55_RS31285	COG1414	Transcriptional regulator
AOX55_RS31300	COG1278	Cold shock
AOX55_RS31305	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOX55_RS31335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOX55_RS31340	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS31355	COG4372	Transposase
AOX55_RS31360	COG3436	PFAM IS66 Orf2 family protein
AOX55_RS31380	COG0010	Belongs to the arginase family
AOX55_RS31425	COG2194	sulfuric ester hydrolase activity
AOX55_RS31435	COG3038	cytochrome b561
AOX55_RS31440	COG0745	RESPONSE REGULATOR receiver
AOX55_RS31445	COG3831	ATPase activity
AOX55_RS31510	COG3344	reverse transcriptase
AOX55_RS31595	COG1126	abc transporter atp-binding protein
AOX55_RS31600	COG0765	amino acid transport
AOX55_RS31605	COG0765	amino acid transport
AOX55_RS31630	COG1012	belongs to the aldehyde dehydrogenase family
AOX55_RS31635	COG2084	Dehydrogenase
AOX55_RS31640	COG0583	DNA-binding transcription factor activity
AOX55_RS31665	COG4886	Leucine-rich repeat (LRR) protein
AOX55_RS31715	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS31725	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS31740	COG1484	DNA-dependent DNA replication
AOX55_RS31745	COG4584	PFAM Integrase catalytic
AOX55_RS31795	COG5490	Phasin protein
AOX55_RS31815	COG1505	serine-type exopeptidase activity
AOX55_RS31850	COG0745	RESPONSE REGULATOR receiver
AOX55_RS31980	COG0673	inositol 2-dehydrogenase activity
AOX55_RS31990	COG0730	response to heat
AOX55_RS32010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOX55_RS32015	COG3153	acetyltransferase
AOX55_RS32020	COG0726	polysaccharide deacetylase
AOX55_RS32025	COG1215	transferase activity, transferring glycosyl groups
AOX55_RS32030	COG1131	(ABC) transporter
AOX55_RS32035	COG0842	Transport permease protein
AOX55_RS32045	COG0275	rRNA processing
AOX55_RS32090	COG2124	cytochrome p450
AOX55_RS32095	COG1141	Ferredoxin
AOX55_RS32105	COG2124	cytochrome p450
AOX55_RS32110	COG1657	PFAM Prenyltransferase squalene oxidase
AOX55_RS32120	COG1304	FMN binding
AOX55_RS32130	COG4974	Belongs to the 'phage' integrase family
AOX55_RS32170	COG4372	Transposase
AOX55_RS32175	COG3436	PFAM IS66 Orf2 family protein
AOX55_RS32180	COG2963	transposase activity
AOX55_RS32240	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS32275	COG4372	Transposase
AOX55_RS32280	COG3436	PFAM IS66 Orf2 family protein
AOX55_RS32295	COG4974	Belongs to the 'phage' integrase family
AOX55_RS32300	COG0517	IMP dehydrogenase activity
AOX55_RS32310	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOX55_RS32315	COG2010	Cytochrome c
AOX55_RS32320	COG0753	catalase activity
AOX55_RS32325	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS32330	COG1484	DNA-dependent DNA replication
AOX55_RS32335	COG4584	PFAM Integrase catalytic
AOX55_RS32350	COG4372	Transposase
AOX55_RS32395	COG1104	cysteine desulfurase activity
AOX55_RS32400	COG0316	Belongs to the HesB IscA family
AOX55_RS32405	COG4166	transmembrane transport
AOX55_RS32425	COG5490	Phasin protein
AOX55_RS32445	COG3180	Ammonia monooxygenase
AOX55_RS32455	COG5554	nitrogen fixation
AOX55_RS32460	COG5554	nitrogen fixation
AOX55_RS32465	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOX55_RS32470	COG0535	radical SAM domain protein
AOX55_RS32475	COG3604	Transcriptional regulator
AOX55_RS32480	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AOX55_RS32485	COG0644	oxidoreductase
AOX55_RS32490	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOX55_RS32495	COG2086	electron transfer activity
AOX55_RS32500	COG0316	Belongs to the HesB IscA family
AOX55_RS32505	COG0678	peroxiredoxin activity
AOX55_RS32515	COG1301	dicarboxylic acid transport
AOX55_RS32520	COG2124	cytochrome p450
AOX55_RS32525	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AOX55_RS32530	COG1028	Short-chain dehydrogenase reductase Sdr
AOX55_RS32535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOX55_RS32540	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AOX55_RS32545	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AOX55_RS32550	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AOX55_RS32555	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AOX55_RS32560	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AOX55_RS32580	COG3383	formate dehydrogenase (NAD+) activity
AOX55_RS32595	COG0612	Peptidase, M16
AOX55_RS32600	COG0612	Peptidase, M16
AOX55_RS32605	COG1396	sequence-specific DNA binding
AOX55_RS32615	COG0738	Major facilitator superfamily
AOX55_RS32620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOX55_RS32625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOX55_RS32720	COG2801	Transposase and inactivated derivatives
AOX55_RS32735	COG2826	transposase and inactivated derivatives, IS30 family
AOX55_RS32740	COG2801	Transposase and inactivated derivatives
AOX55_RS32745	COG3153	acetyltransferase
AOX55_RS32750	COG4453	Protein conserved in bacteria
AOX55_RS32780	COG2963	transposase activity
AOX55_RS32785	COG1396	sequence-specific DNA binding
AOX55_RS32805	COG0662	Cupin 2, conserved barrel domain protein
AOX55_RS32805	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AOX55_RS32810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOX55_RS32825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOX55_RS32845	COG4372	Transposase
AOX55_RS32860	COG1562	ergosterol biosynthetic process
AOX55_RS32865	COG1562	ergosterol biosynthetic process
AOX55_RS32870	COG1233	COG1233 Phytoene dehydrogenase and related
AOX55_RS32875	COG1657	PFAM Prenyltransferase squalene oxidase
AOX55_RS32890	COG0583	DNA-binding transcription factor activity
AOX55_RS32930	COG0071	Belongs to the small heat shock protein (HSP20) family
AOX55_RS32935	COG0071	Belongs to the small heat shock protein (HSP20) family
AOX55_RS32940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOX55_RS32970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOX55_RS32975	COG4644	lycopene metabolic process
AOX55_RS33015	COG4584	PFAM Integrase catalytic
AOX55_RS33015	COG2390	Transcriptional regulator
AOX55_RS33025	COG2963	transposase activity
AOX55_RS33030	COG3436	PFAM IS66 Orf2 family protein
AOX55_RS33050	COG5010	COG0457 FOG TPR repeat
AOX55_RS33055	COG4789	Type iii secretion
AOX55_RS33085	COG4792	protein secretion
AOX55_RS33090	COG4791	protein targeting
AOX55_RS33095	COG4794	Type iii secretion
AOX55_RS33100	COG4790	Type iii secretion
AOX55_RS33105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOX55_RS33115	COG1157	protein secretion by the type III secretion system
AOX55_RS33120	COG1317	bacterial-type flagellum organization
AOX55_RS33150	COG1475	DNA binding
AOX55_RS33160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOX55_RS33165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AOX55_RS33170	COG4264	IucA IucC family
AOX55_RS33175	COG2814	Major facilitator Superfamily
AOX55_RS33185	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS33190	COG5461	TIGRFAM pilus (Caulobacter type) biogenesis lipoprotein CpaD
AOX55_RS33195	COG4964	Belongs to the GSP D family
AOX55_RS33200	COG0745	RESPONSE REGULATOR receiver
AOX55_RS33235	COG1484	DNA-dependent DNA replication
AOX55_RS33265	COG5420	small protein containing a coiled-coil domain
AOX55_RS33275	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AOX55_RS33280	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AOX55_RS33285	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AOX55_RS33305	COG3620	sequence-specific DNA binding
AOX55_RS33310	COG3550	peptidyl-serine autophosphorylation
AOX55_RS33370	COG1476	TRANSCRIPTIONal
AOX55_RS33395	COG3504	Conjugal transfer protein
AOX55_RS33400	COG3701	Conjugal transfer protein
AOX55_RS33405	COG3846	protein secretion by the type IV secretion system
AOX55_RS33415	COG5314	conjugation
AOX55_RS33425	COG3547	Transposase (IS116 IS110 IS902 family)
AOX55_RS33430	COG3451	type IV secretory pathway VirB4
AOX55_RS33435	COG5268	conjugation
AOX55_RS33440	COG3838	Conjugal transfer protein Trbc
AOX55_RS33445	COG4962	Type ii secretion system protein e
AOX55_RS33450	COG3916	Acyl-homoserine-lactone synthase