locus-tag	class	description
CDO22_RS00010	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDO22_RS00015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO22_RS00020	COG1609	Transcriptional regulator
CDO22_RS00025	COG1846	Transcriptional regulator
CDO22_RS00035	COG0523	cobalamin synthesis protein
CDO22_RS00050	COG1280	lysine exporter protein (LysE YggA)
CDO22_RS00065	COG0583	DNA-binding transcription factor activity
CDO22_RS00075	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CDO22_RS00110	COG0800	Aldolase
CDO22_RS00115	COG2954	triphosphatase activity
CDO22_RS00125	COG1054	Belongs to the UPF0176 family
CDO22_RS00135	COG2011	ABC-type metal ion transport system permease component
CDO22_RS00140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDO22_RS00150	COG0673	inositol 2-dehydrogenase activity
CDO22_RS00160	COG2115	Belongs to the xylose isomerase family
CDO22_RS00165	COG1070	Carbohydrate kinase
CDO22_RS00170	COG1609	Transcriptional regulator
CDO22_RS00190	COG1309	transcriptional regulator
CDO22_RS00195	COG3708	Transcriptional regulator
CDO22_RS00195	COG2207	Transcriptional regulator
CDO22_RS00200	COG1253	flavin adenine dinucleotide binding
CDO22_RS00205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDO22_RS00210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDO22_RS00230	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO22_RS00230	COG1793	dna ligase
CDO22_RS00240	COG2111	Na H antiporter
CDO22_RS00240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO22_RS00245	COG1006	Multisubunit Na H antiporter MnhC subunit
CDO22_RS00250	COG0651	ATP synthesis coupled electron transport
CDO22_RS00255	COG1863	multisubunit Na H antiporter MnhE subunit
CDO22_RS00260	COG2212	antiporter activity
CDO22_RS00265	COG1320	monovalent cation:proton antiporter activity
CDO22_RS00275	COG0583	DNA-binding transcription factor activity
CDO22_RS00320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO22_RS00325	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDO22_RS00335	COG4149	molybdate abc transporter
CDO22_RS00340	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CDO22_RS00345	COG2005	Transcriptional regulator
CDO22_RS00345	COG3585	molybdate ion transport
CDO22_RS00360	COG0022	dehydrogenase e1 component
CDO22_RS00380	COG0625	glutathione transferase activity
CDO22_RS00390	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CDO22_RS00410	COG2197	response regulator
CDO22_RS00430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO22_RS00455	COG5001	Diguanylate cyclase
CDO22_RS00455	COG3300	MHYT domain
CDO22_RS00465	COG1802	Transcriptional regulator
CDO22_RS00475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO22_RS00490	COG1126	abc transporter atp-binding protein
CDO22_RS00500	COG0765	amino acid transport
CDO22_RS00505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS00510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO22_RS00520	COG0584	glycerophosphoryl diester phosphodiesterase
CDO22_RS00525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS00545	COG0747	negative chemotaxis
CDO22_RS00550	COG2390	Transcriptional regulator
CDO22_RS00610	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS00625	COG3328	transposase activity
CDO22_RS00630	COG3385	transposase activity
CDO22_RS00640	COG2942	2-epimerase
CDO22_RS00645	COG4702	Belongs to the UPF0303 family
CDO22_RS00650	COG1940	carbohydrate kinase activity
CDO22_RS00680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDO22_RS00685	COG0156	8-amino-7-oxononanoate synthase activity
CDO22_RS00715	COG2267	carboxylic ester hydrolase activity
CDO22_RS00750	COG0010	Belongs to the arginase family
CDO22_RS00755	COG0835	chemotaxis
CDO22_RS00770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDO22_RS00775	COG3383	formate dehydrogenase (NAD+) activity
CDO22_RS00795	COG0583	DNA-binding transcription factor activity
CDO22_RS00815	COG3842	ATPase activity
CDO22_RS00820	COG3842	ATPase activity
CDO22_RS00830	COG0395	ABC-type sugar transport system, permease component
CDO22_RS00845	COG2233	PERMEase
CDO22_RS00850	COG2233	PERMEase
CDO22_RS00865	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDO22_RS00870	COG1121	(ABC) transporter
CDO22_RS00875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO22_RS00880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO22_RS00900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDO22_RS00905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDO22_RS00910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDO22_RS00915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDO22_RS00920	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDO22_RS00935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDO22_RS00955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDO22_RS00965	COG4974	Belongs to the 'phage' integrase family
CDO22_RS00980	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS00995	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO22_RS01000	COG0567	Dehydrogenase, E1 component
CDO22_RS01005	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDO22_RS01010	COG0045	succinate-CoA ligase (ADP-forming) activity
CDO22_RS01015	COG0039	L-malate dehydrogenase activity
CDO22_RS01020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDO22_RS01030	COG3549	Plasmid maintenance system killer
CDO22_RS01035	COG2845	Protein of unknown function (DUF459)
CDO22_RS01045	COG0395	ABC-type sugar transport system, permease component
CDO22_RS01050	COG1175	transmembrane transport
CDO22_RS01075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO22_RS01095	COG2009	succinate dehydrogenase
CDO22_RS01120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDO22_RS01125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDO22_RS01130	COG0181	hydroxymethylbilane synthase activity
CDO22_RS01155	COG0519	Catalyzes the synthesis of GMP from XMP
CDO22_RS01155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDO22_RS01170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDO22_RS01185	COG1217	gtp-binding protein TYPA
CDO22_RS01195	COG4249	Peptidase C14 caspase catalytic subunit p20
CDO22_RS01225	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDO22_RS01230	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDO22_RS01245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDO22_RS01250	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDO22_RS01255	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDO22_RS01260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDO22_RS01265	COG0799	negative regulation of ribosome biogenesis
CDO22_RS01270	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDO22_RS01280	COG0793	Belongs to the peptidase S41A family
CDO22_RS01285	COG2861	carbohydrate metabolic process
CDO22_RS01290	COG0494	nUDIX hydrolase
CDO22_RS01305	COG0587	DNA-directed DNA polymerase activity
CDO22_RS01335	COG0066	3-isopropylmalate dehydratase activity
CDO22_RS01340	COG0251	oxidation-reduction process
CDO22_RS01345	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDO22_RS01355	COG0523	cobalamin synthesis protein
CDO22_RS01370	COG3118	belongs to the thioredoxin family
CDO22_RS01375	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO22_RS01380	COG2835	tetraacyldisaccharide 4'-kinase activity
CDO22_RS01390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO22_RS01395	COG1946	Acyl-CoA thioesterase
CDO22_RS01400	COG0347	Belongs to the P(II) protein family
CDO22_RS01405	COG0004	ammonium transporteR
CDO22_RS01410	COG1674	ftsk spoiiie
CDO22_RS01415	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDO22_RS01435	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS01440	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS01445	COG1129	ABC transporter
CDO22_RS01450	COG1940	carbohydrate kinase activity
CDO22_RS01455	COG1940	carbohydrate kinase activity
CDO22_RS01470	COG0745	RESPONSE REGULATOR receiver
CDO22_RS01485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDO22_RS01500	COG0477	Major facilitator Superfamily
CDO22_RS01505	COG0137	argininosuccinate synthase activity
CDO22_RS01520	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS01530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDO22_RS01550	COG2154	pterin-4-alpha-carbinolamine dehydratase
CDO22_RS01555	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CDO22_RS01565	COG4181	ATPase activity
CDO22_RS01575	COG0670	Belongs to the BI1 family
CDO22_RS01585	COG0740	serine-type endopeptidase activity
CDO22_RS01595	COG0640	Transcriptional regulator
CDO22_RS01610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDO22_RS01615	COG4133	protoheme IX ABC transporter activity
CDO22_RS01620	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO22_RS01625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO22_RS01645	COG2917	probably involved in intracellular septation
CDO22_RS01650	COG0552	protein localization to endoplasmic reticulum
CDO22_RS01655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDO22_RS01660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDO22_RS01665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDO22_RS01670	COG0287	Prephenate dehydrogenase
CDO22_RS01670	COG1605	Chorismate mutase
CDO22_RS01675	COG0228	four-way junction DNA binding
CDO22_RS01680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDO22_RS01685	COG0336	Belongs to the RNA methyltransferase TrmD family
CDO22_RS01695	COG0335	large ribosomal subunit rRNA binding
CDO22_RS01700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO22_RS01705	COG0765	amino acid transport
CDO22_RS01710	COG0488	(ABC) transporter
CDO22_RS01735	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CDO22_RS01745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO22_RS01750	COG1329	Transcriptional regulator
CDO22_RS01755	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDO22_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS01775	COG0183	Belongs to the thiolase family
CDO22_RS01780	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CDO22_RS01785	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDO22_RS01790	COG0625	glutathione transferase activity
CDO22_RS01795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDO22_RS01800	COG0142	geranyltranstransferase activity
CDO22_RS01805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO22_RS01815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDO22_RS01820	COG2223	nitrite transmembrane transporter activity
CDO22_RS01830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO22_RS01835	COG0765	amino acid transport
CDO22_RS01840	COG1126	abc transporter atp-binding protein
CDO22_RS01845	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDO22_RS01855	COG1132	(ABC) transporter
CDO22_RS01870	COG3459	Glycosyltransferase 36 associated
CDO22_RS01885	COG5383	Protein conserved in bacteria
CDO22_RS01900	COG0436	Aminotransferase
CDO22_RS01910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO22_RS01925	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS01935	COG3842	ATPase activity
CDO22_RS01940	COG0395	ABC-type sugar transport system, permease component
CDO22_RS01945	COG1175	transmembrane transport
CDO22_RS01950	COG1653	transport
CDO22_RS01955	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS01960	COG1024	Enoyl-CoA hydratase
CDO22_RS01970	COG0673	inositol 2-dehydrogenase activity
CDO22_RS01975	COG1609	Transcriptional regulator
CDO22_RS01985	COG0339	signal peptide processing
CDO22_RS01995	COG0473	3-isopropylmalate dehydrogenase activity
CDO22_RS02000	COG0671	phosphoesterase, PA-phosphatase related
CDO22_RS02025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDO22_RS02040	COG0288	reversible hydration of carbon dioxide
CDO22_RS02050	COG2902	Dehydrogenase
CDO22_RS02065	COG0138	bifunctional purine biosynthesis protein purh
CDO22_RS02075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO22_RS02075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDO22_RS02080	COG0501	Belongs to the peptidase M48B family
CDO22_RS02090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO22_RS02110	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDO22_RS02115	COG0495	leucyl-tRNA aminoacylation
CDO22_RS02140	COG0357	Ribosomal RNA small subunit methyltransferase G
CDO22_RS02145	COG0445	tRNA wobble uridine modification
CDO22_RS02150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDO22_RS02155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDO22_RS02160	COG1981	membrane
CDO22_RS02165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDO22_RS02170	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDO22_RS02175	COG0424	maF-like protein
CDO22_RS02180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDO22_RS02185	COG0237	dephospho-CoA kinase activity
CDO22_RS02190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDO22_RS02195	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CDO22_RS02245	COG1802	Transcriptional regulator
CDO22_RS02250	COG2721	sulfolactate sulfo-lyase activity
CDO22_RS02270	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS02275	COG1063	alcohol dehydrogenase
CDO22_RS02295	COG0135	phosphoribosylanthranilate isomerase activity
CDO22_RS02300	COG0133	tryptophan synthase activity
CDO22_RS02305	COG0159	tryptophan synthase activity
CDO22_RS02310	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDO22_RS02320	COG3385	transposase activity
CDO22_RS02330	COG1074	ATP-dependent DNA helicase activity
CDO22_RS02335	COG2887	Belongs to the helicase family. UvrD subfamily
CDO22_RS02340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDO22_RS02345	COG3178	'Phosphotransferase
CDO22_RS02350	COG2205	protein histidine kinase activity
CDO22_RS02355	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDO22_RS02365	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO22_RS02365	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO22_RS02380	COG2205	protein histidine kinase activity
CDO22_RS02385	COG0745	RESPONSE REGULATOR receiver
CDO22_RS02390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CDO22_RS02400	COG1652	LysM domain
CDO22_RS02410	COG1072	(Pantothenic acid kinase))
CDO22_RS02415	COG0140	phosphoribosyl-ATP diphosphatase activity
CDO22_RS02420	COG0107	imidazoleglycerol-phosphate synthase activity
CDO22_RS02425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDO22_RS02430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDO22_RS02440	COG0131	Imidazoleglycerol-phosphate dehydratase
CDO22_RS02445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CDO22_RS02455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CDO22_RS02465	COG2124	cytochrome p450
CDO22_RS02475	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDO22_RS02490	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CDO22_RS02500	COG1643	Atp-dependent helicase
CDO22_RS02505	COG4136	ATPase activity
CDO22_RS02510	COG4135	transport system, permease component
CDO22_RS02515	COG4134	Bacterial extracellular solute-binding protein
CDO22_RS02575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDO22_RS02580	COG0626	cystathionine gamma-synthase activity
CDO22_RS02605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDO22_RS02615	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO22_RS02615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO22_RS02620	COG4311	Sarcosine oxidase, delta subunit
CDO22_RS02625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS02630	COG4977	sequence-specific DNA binding
CDO22_RS02635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDO22_RS02640	COG2218	PFAM glutamate synthase alpha subunit domain protein
CDO22_RS02645	COG0069	glutamate synthase activity
CDO22_RS02650	COG0174	glutamine synthetase
CDO22_RS02665	COG0531	amino acid
CDO22_RS02695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO22_RS02720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO22_RS02730	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CDO22_RS02735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS02745	COG2186	Transcriptional regulator
CDO22_RS02760	COG3842	ATPase activity
CDO22_RS02770	COG0673	inositol 2-dehydrogenase activity
CDO22_RS02775	COG0395	ABC-type sugar transport system, permease component
CDO22_RS02780	COG1175	transmembrane transport
CDO22_RS02785	COG1653	transport
CDO22_RS02790	COG1309	transcriptional regulator
CDO22_RS02795	COG0673	inositol 2-dehydrogenase activity
CDO22_RS02815	COG0673	inositol 2-dehydrogenase activity
CDO22_RS02830	COG3845	ABC transporter
CDO22_RS02835	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS02840	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS02855	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CDO22_RS02860	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDO22_RS02865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDO22_RS02870	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CDO22_RS02905	COG4964	Belongs to the GSP D family
CDO22_RS02935	COG3385	transposase activity
CDO22_RS02945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO22_RS02955	COG0791	NLP P60 protein
CDO22_RS02965	COG4172	Belongs to the ABC transporter superfamily
CDO22_RS02970	COG4239	(ABC) transporter, permease
CDO22_RS02975	COG4174	ABC transporter (Permease)
CDO22_RS02980	COG4166	transmembrane transport
CDO22_RS02985	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CDO22_RS02990	COG1803	Methylglyoxal synthase
CDO22_RS02995	COG0837	glucose binding
CDO22_RS03000	COG1132	(ABC) transporter
CDO22_RS03005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDO22_RS03010	COG0588	phosphoglycerate mutase activity
CDO22_RS03015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO22_RS03040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO22_RS03060	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO22_RS03060	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO22_RS03070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO22_RS03090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO22_RS03095	COG0443	Heat shock 70 kDa protein
CDO22_RS03100	COG0484	heat shock protein binding
CDO22_RS03115	COG0306	phosphate transporter
CDO22_RS03120	COG1392	Phosphate transport regulator
CDO22_RS03125	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDO22_RS03145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO22_RS03150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO22_RS03160	COG0673	inositol 2-dehydrogenase activity
CDO22_RS03165	COG0395	ABC-type sugar transport system, permease component
CDO22_RS03170	COG1175	transmembrane transport
CDO22_RS03180	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDO22_RS03185	COG2971	BadF BadG BcrA BcrD
CDO22_RS03190	COG2188	Transcriptional regulator
CDO22_RS03195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO22_RS03200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDO22_RS03210	COG3142	Participates in the control of copper homeostasis
CDO22_RS03215	COG1940	carbohydrate kinase activity
CDO22_RS03230	COG2900	Belongs to the SlyX family
CDO22_RS03235	COG1744	ABC transporter substrate-binding protein PnrA-like
CDO22_RS03240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO22_RS03265	COG1917	Cupin 2, conserved barrel domain protein
CDO22_RS03265	COG2207	Transcriptional regulator
CDO22_RS03270	COG2814	Major facilitator Superfamily
CDO22_RS03275	COG4771	TonB-dependent receptor
CDO22_RS03285	COG2814	Major facilitator Superfamily
CDO22_RS03305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO22_RS03310	COG3474	cytochrome
CDO22_RS03315	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CDO22_RS03320	COG0077	Prephenate dehydratase
CDO22_RS03320	COG1605	Chorismate mutase
CDO22_RS03335	COG2378	regulation of single-species biofilm formation
CDO22_RS03340	COG2816	NAD+ diphosphatase activity
CDO22_RS03355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDO22_RS03360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDO22_RS03370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDO22_RS03375	COG2951	lytic endotransglycosylase activity
CDO22_RS03380	COG2814	Major facilitator Superfamily
CDO22_RS03385	COG0779	Required for maturation of 30S ribosomal subunits
CDO22_RS03390	COG0195	Participates in both transcription termination and antitermination
CDO22_RS03390	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDO22_RS03400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDO22_RS03405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDO22_RS03410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDO22_RS03420	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDO22_RS03425	COG1185	polyribonucleotide nucleotidyltransferase activity
CDO22_RS03435	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDO22_RS03445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO22_RS03455	COG2860	membrane
CDO22_RS03475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDO22_RS03480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDO22_RS03485	COG0539	negative regulation of cytoplasmic translation
CDO22_RS03515	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO22_RS03520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO22_RS03535	COG2801	Transposase and inactivated derivatives
CDO22_RS03535	COG3415	Transposase
CDO22_RS03560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO22_RS03570	COG0481	GTPase activity
CDO22_RS03590	COG3932	Exopolysaccharide synthesis, ExoD
CDO22_RS03595	COG2885	chlorophyll binding
CDO22_RS03600	COG1509	lysine 2,3-aminomutase activity
CDO22_RS03605	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CDO22_RS03610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDO22_RS03615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO22_RS03635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDO22_RS03640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDO22_RS03645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDO22_RS03650	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDO22_RS03655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO22_RS03655	COG0072	phenylalanine-tRNA ligase activity
CDO22_RS03665	COG0667	Aldo Keto reductase
CDO22_RS03690	COG0667	Aldo Keto reductase
CDO22_RS03710	COG1570	exodeoxyribonuclease VII activity
CDO22_RS03715	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDO22_RS03720	COG1846	Transcriptional regulator
CDO22_RS03725	COG0697	spore germination
CDO22_RS03730	COG2309	aminopeptidase activity
CDO22_RS03735	COG0625	glutathione transferase activity
CDO22_RS03750	COG1393	Belongs to the ArsC family
CDO22_RS03755	COG1448	Aminotransferase
CDO22_RS03790	COG0519	Catalyzes the synthesis of GMP from XMP
CDO22_RS03790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDO22_RS03805	COG1247	-acetyltransferase
CDO22_RS03840	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDO22_RS03850	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDO22_RS03860	COG1968	undecaprenyl-diphosphatase activity
CDO22_RS03870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS03880	COG0284	orotidine-5'-phosphate decarboxylase activity
CDO22_RS03890	COG3963	phosphatidate phosphatase activity
CDO22_RS03900	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDO22_RS03905	COG0792	nuclease activity
CDO22_RS03910	COG0189	ligase activity
CDO22_RS03920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDO22_RS03935	COG0697	spore germination
CDO22_RS03940	COG1522	sequence-specific DNA binding
CDO22_RS03945	COG0756	dUTP diphosphatase activity
CDO22_RS03950	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDO22_RS03965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS03975	COG3718	enzyme involved in inositol metabolism
CDO22_RS03980	COG1082	Xylose isomerase domain protein TIM barrel
CDO22_RS04015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDO22_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS04045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDO22_RS04050	COG2226	methyltransferase
CDO22_RS04055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDO22_RS04060	COG1024	Enoyl-CoA hydratase
CDO22_RS04065	COG0268	Binds directly to 16S ribosomal RNA
CDO22_RS04075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDO22_RS04080	COG3795	YCII-related domain
CDO22_RS04085	COG4941	Belongs to the sigma-70 factor family
CDO22_RS04100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDO22_RS04105	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDO22_RS04115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDO22_RS04120	COG1420	regulation of RNA biosynthetic process
CDO22_RS04125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDO22_RS04135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO22_RS04140	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDO22_RS04145	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO22_RS04150	COG1137	ATPase activity
CDO22_RS04155	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDO22_RS04165	COG0616	signal peptide processing
CDO22_RS04170	COG0776	regulation of translation
CDO22_RS04185	COG0116	Belongs to the methyltransferase superfamily
CDO22_RS04185	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDO22_RS04190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO22_RS04195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDO22_RS04200	COG2205	protein histidine kinase activity
CDO22_RS04200	COG5002	protein histidine kinase activity
CDO22_RS04200	COG0784	Response regulator, receiver
CDO22_RS04210	COG0280	phosphate acetyltransferase
CDO22_RS04210	COG0281	malic enzyme
CDO22_RS04215	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDO22_RS04220	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CDO22_RS04225	COG0728	peptidoglycan biosynthetic process
CDO22_RS04235	COG0180	Tryptophanyl-tRNA synthetase
CDO22_RS04245	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDO22_RS04265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDO22_RS04270	COG1702	phosphate starvation-inducible protein PhoH
CDO22_RS04275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDO22_RS04280	COG4535	Mg2 and Co2 transporter CorC
CDO22_RS04285	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CDO22_RS04290	COG1396	sequence-specific DNA binding
CDO22_RS04295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDO22_RS04300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDO22_RS04310	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO22_RS04315	COG1957	nucleoside hydrolase
CDO22_RS04320	COG0840	transmembrane signaling receptor activity
CDO22_RS04325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO22_RS04335	COG0242	peptide deformylase activity
CDO22_RS04340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO22_RS04345	COG0101	tRNA pseudouridine synthase activity
CDO22_RS04355	COG2801	Transposase and inactivated derivatives
CDO22_RS04365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO22_RS04380	COG0657	acetylesterase activity
CDO22_RS04385	COG0583	DNA-binding transcription factor activity
CDO22_RS04395	COG0513	Belongs to the DEAD box helicase family
CDO22_RS04405	COG2171	N-acyltransferase activity
CDO22_RS04425	COG2169	Transcriptional regulator
CDO22_RS04425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO22_RS04435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDO22_RS04445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO22_RS04455	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDO22_RS04465	COG0706	membrane insertase activity
CDO22_RS04470	COG0594	ribonuclease P activity
CDO22_RS04475	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CDO22_RS04500	COG5002	protein histidine kinase activity
CDO22_RS04530	COG1304	FMN binding
CDO22_RS04580	COG0667	Aldo Keto reductase
CDO22_RS04620	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO22_RS04630	COG2259	Doxx family
CDO22_RS04660	COG1072	(Pantothenic acid kinase))
CDO22_RS04665	COG0418	dihydroorotase activity
CDO22_RS04670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDO22_RS04680	COG0166	Belongs to the GPI family
CDO22_RS04685	COG0318	PFAM AMP-dependent synthetase and ligase
CDO22_RS04690	COG2814	Major facilitator Superfamily
CDO22_RS04695	COG0628	permease
CDO22_RS04710	COG4589	Belongs to the CDS family
CDO22_RS04735	COG2326	polyphosphate kinase activity
CDO22_RS04740	COG5002	protein histidine kinase activity
CDO22_RS04750	COG0573	inorganic phosphate transmembrane transporter activity
CDO22_RS04760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDO22_RS04765	COG0704	Plays a role in the regulation of phosphate uptake
CDO22_RS04770	COG0745	RESPONSE REGULATOR receiver
CDO22_RS04780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO22_RS04785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDO22_RS04795	COG2967	ApaG domain
CDO22_RS04800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDO22_RS04810	COG0717	Belongs to the dCTP deaminase family
CDO22_RS04820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO22_RS04840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDO22_RS04845	COG0387	Pfam Sodium calcium exchanger
CDO22_RS04860	COG1024	Enoyl-CoA hydratase
CDO22_RS04860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO22_RS04865	COG0183	Belongs to the thiolase family
CDO22_RS04870	COG1960	acyl-CoA dehydrogenase activity
CDO22_RS04880	COG0730	response to heat
CDO22_RS04905	COG1201	RNA secondary structure unwinding
CDO22_RS04910	COG1959	2 iron, 2 sulfur cluster binding
CDO22_RS04915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO22_RS04940	COG0534	Mate efflux family protein
CDO22_RS04945	COG0167	dihydroorotate dehydrogenase activity
CDO22_RS04970	COG1970	mechanosensitive ion channel activity
CDO22_RS04975	COG0436	Aminotransferase
CDO22_RS04990	COG1294	oxidase, subunit
CDO22_RS04995	COG1271	oxidase subunit
CDO22_RS05000	COG1473	amidohydrolase
CDO22_RS05010	COG4215	(ABC) transporter
CDO22_RS05015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO22_RS05025	COG1309	transcriptional regulator
CDO22_RS05055	COG1959	2 iron, 2 sulfur cluster binding
CDO22_RS05060	COG0517	IMP dehydrogenase activity
CDO22_RS05060	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDO22_RS05070	COG1368	sulfuric ester hydrolase activity
CDO22_RS05075	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS05080	COG0156	8-amino-7-oxononanoate synthase activity
CDO22_RS05095	COG1335	isochorismatase
CDO22_RS05100	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDO22_RS05130	COG2132	Multicopper oxidase
CDO22_RS05160	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDO22_RS05170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDO22_RS05175	COG5328	Belongs to the UPF0262 family
CDO22_RS05185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDO22_RS05190	COG0424	maF-like protein
CDO22_RS05195	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDO22_RS05245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDO22_RS05260	COG4952	isomerase
CDO22_RS05265	COG3347	Dehydrogenase
CDO22_RS05265	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS05270	COG1349	DNA-binding transcription factor activity
CDO22_RS05280	COG1129	ABC transporter
CDO22_RS05285	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS05295	COG3254	rhamnose metabolic process
CDO22_RS05305	COG0840	transmembrane signaling receptor activity
CDO22_RS05315	COG0745	RESPONSE REGULATOR receiver
CDO22_RS05320	COG0643	Histidine kinase
CDO22_RS05320	COG2198	Histidine kinase
CDO22_RS05325	COG0835	chemotaxis
CDO22_RS05330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CDO22_RS05335	COG2201	protein-glutamate methylesterase activity
CDO22_RS05340	COG0745	RESPONSE REGULATOR receiver
CDO22_RS05345	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CDO22_RS05360	COG1766	The M ring may be actively involved in energy transduction
CDO22_RS05365	COG2771	luxR family
CDO22_RS05380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO22_RS05385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO22_RS05390	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO22_RS05395	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO22_RS05400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDO22_RS05410	COG4786	Flagellar basal body rod
CDO22_RS05415	COG1157	protein secretion by the type III secretion system
CDO22_RS05425	COG1815	bacterial-type flagellum-dependent cell motility
CDO22_RS05430	COG1558	bacterial-type flagellum-dependent cell motility
CDO22_RS05435	COG1677	Flagellar hook-basal body complex protein FliE
CDO22_RS05440	COG4786	Flagellar basal body rod
CDO22_RS05445	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CDO22_RS05450	COG1706	bacterial-type flagellum-dependent cell motility
CDO22_RS05460	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CDO22_RS05470	COG1338	Plays a role in the flagellum-specific transport system
CDO22_RS05475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO22_RS05480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO22_RS05485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO22_RS05490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO22_RS05500	COG1360	Flagellar Motor Protein
CDO22_RS05525	COG1749	Flagellar hook protein flgE
CDO22_RS05545	COG5443	negative regulation of bacterial-type flagellum assembly
CDO22_RS05550	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CDO22_RS05555	COG4794	Type iii secretion
CDO22_RS05560	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO22_RS05595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDO22_RS05600	COG1609	Transcriptional regulator
CDO22_RS05605	COG1653	transport
CDO22_RS05610	COG1175	transmembrane transport
CDO22_RS05615	COG0395	ABC-type sugar transport system, permease component
CDO22_RS05620	COG0366	Alpha amylase catalytic
CDO22_RS05625	COG3842	ATPase activity
CDO22_RS05635	COG3385	transposase activity
CDO22_RS05640	COG0129	dihydroxy-acid dehydratase activity
CDO22_RS05645	COG0363	glucosamine-6-phosphate deaminase activity
CDO22_RS05650	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDO22_RS05655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS05665	COG2081	HI0933 family
CDO22_RS05675	COG2972	Histidine kinase
CDO22_RS05675	COG0840	transmembrane signaling receptor activity
CDO22_RS05695	COG2224	Isocitrate lyase
CDO22_RS05700	COG1396	sequence-specific DNA binding
CDO22_RS05700	COG3800	Transcriptional regulator
CDO22_RS05710	COG3842	ATPase activity
CDO22_RS05715	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO22_RS05720	COG1177	transmembrane transport
CDO22_RS05730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO22_RS05735	COG1178	ABC-type Fe3 transport system permease component
CDO22_RS05740	COG2205	protein histidine kinase activity
CDO22_RS05775	COG4269	membrane
CDO22_RS05785	COG1840	ABC-type Fe3 transport system, periplasmic component
CDO22_RS05790	COG1959	2 iron, 2 sulfur cluster binding
CDO22_RS05795	COG0747	negative chemotaxis
CDO22_RS05800	COG0601	transmembrane transport
CDO22_RS05805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS05810	COG0444	Belongs to the ABC transporter superfamily
CDO22_RS05815	COG4608	Belongs to the ABC transporter superfamily
CDO22_RS05820	COG0251	oxidation-reduction process
CDO22_RS05835	COG0784	Response regulator, receiver
CDO22_RS05860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS05870	COG1285	pathogenesis
CDO22_RS05925	COG2059	Chromate
CDO22_RS05950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDO22_RS05960	COG0477	Major facilitator Superfamily
CDO22_RS05980	COG0412	Dienelactone hydrolase
CDO22_RS05985	COG0583	DNA-binding transcription factor activity
CDO22_RS05990	COG0753	catalase activity
CDO22_RS05995	COG0583	DNA-binding transcription factor activity
CDO22_RS06030	COG0306	phosphate transporter
CDO22_RS06040	COG1725	Transcriptional regulator
CDO22_RS06050	COG0583	DNA-binding transcription factor activity
CDO22_RS06055	COG0277	FAD linked oxidase domain protein
CDO22_RS06060	COG0277	FAD linked oxidase domain protein
CDO22_RS06065	COG0247	lactate metabolic process
CDO22_RS06070	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS06070	COG1388	LysM domain
CDO22_RS06075	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS06080	COG2818	Glycosylase
CDO22_RS06085	COG1953	Uracil, thiamine, allantoin
CDO22_RS06100	COG0124	histidyl-tRNA synthetase
CDO22_RS06105	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDO22_RS06110	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDO22_RS06115	COG0625	glutathione transferase activity
CDO22_RS06130	COG0459	protein refolding
CDO22_RS06135	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO22_RS06150	COG0196	riboflavin kinase activity
CDO22_RS06155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDO22_RS06170	COG0590	tRNA wobble adenosine to inosine editing
CDO22_RS06175	COG1187	pseudouridine synthase activity
CDO22_RS06180	COG0742	ribosomal rna small subunit methyltransferase
CDO22_RS06185	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO22_RS06190	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
CDO22_RS06200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO22_RS06200	COG0475	glutathione-regulated potassium exporter activity
CDO22_RS06205	COG0312	modulator of DNA gyrase
CDO22_RS06210	COG0483	inositol monophosphate 1-phosphatase activity
CDO22_RS06220	COG1519	Transferase
CDO22_RS06230	COG1663	tetraacyldisaccharide 4'-kinase activity
CDO22_RS06245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDO22_RS06255	COG5001	Diguanylate cyclase
CDO22_RS06255	COG3300	MHYT domain
CDO22_RS06260	COG0583	DNA-binding transcription factor activity
CDO22_RS06265	COG5598	trimethylamine methyltransferase
CDO22_RS06280	COG0129	dihydroxy-acid dehydratase activity
CDO22_RS06285	COG3386	PFAM SMP-30 Gluconolaconase
CDO22_RS06290	COG0800	Aldolase
CDO22_RS06295	COG3734	2-keto-3-deoxy-galactonokinase
CDO22_RS06300	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS06305	COG1414	Transcriptional regulator
CDO22_RS06315	COG2771	luxR family
CDO22_RS06320	COG0489	protein tyrosine kinase activity
CDO22_RS06325	COG0598	Magnesium transport protein CorA
CDO22_RS06330	COG3158	transport of potassium into the cell
CDO22_RS06345	COG0356	it plays a direct role in the translocation of protons across the membrane
CDO22_RS06350	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDO22_RS06355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDO22_RS06360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDO22_RS06370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDO22_RS06390	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDO22_RS06395	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDO22_RS06405	COG0142	geranyltranstransferase activity
CDO22_RS06430	COG0752	glycyl-tRNA synthetase alpha subunit
CDO22_RS06440	COG1704	LemA family
CDO22_RS06450	COG0751	glycine-tRNA ligase activity
CDO22_RS06455	COG1683	Conserved Protein
CDO22_RS06465	COG0151	Belongs to the GarS family
CDO22_RS06470	COG5001	Diguanylate cyclase
CDO22_RS06480	COG2223	nitrite transmembrane transporter activity
CDO22_RS06485	COG4977	sequence-specific DNA binding
CDO22_RS06490	COG3713	MltA-interacting MipA family protein
CDO22_RS06495	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDO22_RS06515	COG0009	L-threonylcarbamoyladenylate synthase
CDO22_RS06525	COG4638	Rieske (2fe-2S)
CDO22_RS06530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDO22_RS06555	COG1960	acyl-CoA dehydrogenase activity
CDO22_RS06575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDO22_RS06585	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDO22_RS06590	COG1741	Belongs to the pirin family
CDO22_RS06595	COG1722	exodeoxyribonuclease VII activity
CDO22_RS06600	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDO22_RS06605	COG1063	alcohol dehydrogenase
CDO22_RS06615	COG0183	Belongs to the thiolase family
CDO22_RS06620	COG0318	PFAM AMP-dependent synthetase and ligase
CDO22_RS06625	COG1268	BioY protein
CDO22_RS06630	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDO22_RS06635	COG1122	ATPase activity
CDO22_RS06640	COG3214	Protein conserved in bacteria
CDO22_RS06645	COG0312	modulator of DNA gyrase
CDO22_RS06660	COG0259	pyridoxamine-phosphate oxidase activity
CDO22_RS06670	COG0484	heat shock protein binding
CDO22_RS06675	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDO22_RS06690	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDO22_RS06695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDO22_RS06695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDO22_RS06710	COG1565	acr, cog1565
CDO22_RS06710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO22_RS06715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO22_RS06720	COG0109	protoheme IX farnesyltransferase activity
CDO22_RS06730	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CDO22_RS06750	COG3346	SURF1 family
CDO22_RS06755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDO22_RS06760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDO22_RS06765	COG0328	RNA-DNA hybrid ribonuclease activity
CDO22_RS06770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDO22_RS06770	COG0678	peroxiredoxin activity
CDO22_RS06780	COG1678	Uncharacterized ACR, COG1678
CDO22_RS06785	COG5001	Diguanylate cyclase
CDO22_RS06790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO22_RS06795	COG0612	Peptidase, M16
CDO22_RS06815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO22_RS06825	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CDO22_RS06835	COG1194	a g-specific adenine glycosylase
CDO22_RS06855	COG1196	nuclear chromosome segregation
CDO22_RS06860	COG0574	Belongs to the PEP-utilizing enzyme family
CDO22_RS06860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDO22_RS06895	COG3264	Mechanosensitive ion channel
CDO22_RS06895	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CDO22_RS06920	COG2895	sulfate adenylyltransferase (ATP) activity
CDO22_RS06925	COG0175	sulfate reduction
CDO22_RS06930	COG0175	sulfate reduction
CDO22_RS06945	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CDO22_RS06955	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS06960	COG3119	arylsulfatase activity
CDO22_RS06965	COG1309	transcriptional regulator
CDO22_RS06975	COG5001	Diguanylate cyclase
CDO22_RS06975	COG3300	MHYT domain
CDO22_RS07005	COG0583	DNA-binding transcription factor activity
CDO22_RS07020	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS07020	COG1388	LysM domain
CDO22_RS07025	COG1846	Transcriptional regulator
CDO22_RS07030	COG1764	response to oxidative stress
CDO22_RS07035	COG2824	Alkylphosphonate utilization operon protein PhnA
CDO22_RS07040	COG0433	COG0433 Predicted ATPase
CDO22_RS07050	COG0656	L-ascorbic acid biosynthetic process
CDO22_RS07060	COG4106	trans-aconitate 2-methyltransferase activity
CDO22_RS07095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDO22_RS07115	COG2010	Cytochrome c
CDO22_RS07125	COG0789	Transcriptional regulator
CDO22_RS07135	COG4993	Dehydrogenase
CDO22_RS07140	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CDO22_RS07155	COG2514	catechol 2,3-dioxygenase activity
CDO22_RS07170	COG1272	protein, Hemolysin III
CDO22_RS07180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO22_RS07185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO22_RS07185	COG2111	Na H antiporter
CDO22_RS07190	COG2111	Na H antiporter
CDO22_RS07195	COG1006	Multisubunit Na H antiporter MnhC subunit
CDO22_RS07200	COG0651	ATP synthesis coupled electron transport
CDO22_RS07205	COG1863	multisubunit Na H antiporter MnhE subunit
CDO22_RS07210	COG2212	antiporter activity
CDO22_RS07215	COG1320	monovalent cation:proton antiporter activity
CDO22_RS07220	COG4957	zinc ion binding
CDO22_RS07225	COG2166	iron-sulfur cluster assembly
CDO22_RS07235	COG2205	protein histidine kinase activity
CDO22_RS07285	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO22_RS07290	COG2983	Belongs to the UPF0260 family
CDO22_RS07325	COG4235	cytochrome complex assembly
CDO22_RS07330	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CDO22_RS07335	COG1138	Cytochrome C-type biogenesis protein
CDO22_RS07340	COG3088	subunit of a heme lyase
CDO22_RS07345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO22_RS07350	COG0745	RESPONSE REGULATOR receiver
CDO22_RS07355	COG2205	protein histidine kinase activity
CDO22_RS07360	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDO22_RS07365	COG2202	Pas domain
CDO22_RS07365	COG2205	protein histidine kinase activity
CDO22_RS07370	COG0308	aminopeptidase N
CDO22_RS07380	COG2814	Major facilitator Superfamily
CDO22_RS07395	COG1573	uracil-dna glycosylase
CDO22_RS07400	COG0443	Heat shock 70 kDa protein
CDO22_RS07420	COG4176	ABC-type proline glycine betaine transport system permease component
CDO22_RS07430	COG1733	regulation of RNA biosynthetic process
CDO22_RS07440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO22_RS07445	COG0463	Glycosyl transferase, family 2
CDO22_RS07455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDO22_RS07460	COG1742	UPF0060 membrane protein
CDO22_RS07475	COG0625	glutathione transferase activity
CDO22_RS07490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO22_RS07505	COG3093	addiction module antidote protein HigA
CDO22_RS07510	COG3549	Plasmid maintenance system killer
CDO22_RS07520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDO22_RS07525	COG4974	Belongs to the 'phage' integrase family
CDO22_RS07530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDO22_RS07540	COG0741	lytic transglycosylase activity
CDO22_RS07545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO22_RS07550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDO22_RS07570	COG1758	RNA polymerase activity
CDO22_RS07600	COG0736	holo-[acyl-carrier-protein] synthase activity
CDO22_RS07605	COG0681	Belongs to the peptidase S26 family
CDO22_RS07610	COG0571	ribonuclease III activity
CDO22_RS07615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDO22_RS07620	COG0431	NADPH-dependent FMN reductase
CDO22_RS07640	COG0584	glycerophosphoryl diester phosphodiesterase
CDO22_RS07645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO22_RS07650	COG2183	response to ionizing radiation
CDO22_RS07660	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDO22_RS07665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS07685	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS07690	COG1381	Involved in DNA repair and RecF pathway recombination
CDO22_RS07705	COG1418	mRNA catabolic process
CDO22_RS07720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDO22_RS07725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CDO22_RS07735	COG2032	superoxide dismutase activity
CDO22_RS07740	COG2274	protein secretion by the type I secretion system
CDO22_RS07765	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CDO22_RS07790	COG1051	belongs to the nudix hydrolase family
CDO22_RS07810	COG0215	cysteine-tRNA ligase activity
CDO22_RS07835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDO22_RS07840	COG2962	Rard protein
CDO22_RS07855	COG5265	(ABC) transporter
CDO22_RS07860	COG0688	phosphatidylethanolamine metabolic process
CDO22_RS07865	COG1183	phosphatidylcholine synthase activity
CDO22_RS07870	COG4221	oxidoreductase activity
CDO22_RS07875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDO22_RS07890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDO22_RS07910	COG0305	Participates in initiation and elongation during chromosome replication
CDO22_RS07930	COG0359	binds to the 23S rRNA
CDO22_RS07940	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDO22_RS07945	COG0360	Binds together with S18 to 16S ribosomal RNA
CDO22_RS07955	COG0667	Aldo Keto reductase
CDO22_RS07960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDO22_RS07970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO22_RS07975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO22_RS07980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDO22_RS07985	COG1561	YicC-like family, N-terminal region
CDO22_RS07990	COG0194	GDP metabolic process
CDO22_RS08000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDO22_RS08005	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO22_RS08035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO22_RS08060	COG0488	(ABC) transporter
CDO22_RS08070	COG0318	PFAM AMP-dependent synthetase and ligase
CDO22_RS08085	COG0105	UTP biosynthetic process
CDO22_RS08110	COG0314	molybdopterin synthase activity
CDO22_RS08125	COG0322	excinuclease ABC activity
CDO22_RS08130	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS08155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDO22_RS08160	COG0243	molybdopterin cofactor binding
CDO22_RS08165	COG0494	nUDIX hydrolase
CDO22_RS08180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDO22_RS08185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDO22_RS08190	COG0628	permease
CDO22_RS08200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CDO22_RS08205	COG0248	Ppx GppA phosphatase
CDO22_RS08220	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CDO22_RS08225	COG2132	Multicopper oxidase
CDO22_RS08240	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDO22_RS08250	COG0459	protein refolding
CDO22_RS08265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDO22_RS08280	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CDO22_RS08290	COG0113	porphobilinogen synthase activity
CDO22_RS08305	COG2989	Protein conserved in bacteria
CDO22_RS08310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDO22_RS08315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDO22_RS08320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO22_RS08320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO22_RS08335	COG0519	Catalyzes the synthesis of GMP from XMP
CDO22_RS08345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDO22_RS08350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO22_RS08355	COG2814	Major facilitator Superfamily
CDO22_RS08360	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CDO22_RS08380	COG0416	fatty acid biosynthetic process
CDO22_RS08385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO22_RS08390	COG0776	regulation of translation
CDO22_RS08405	COG4974	Belongs to the 'phage' integrase family
CDO22_RS08450	COG0629	single-stranded DNA binding
CDO22_RS08455	COG4712	double-strand break repair protein
CDO22_RS08570	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDO22_RS08590	COG1783	phage Terminase large subunit
CDO22_RS08690	COG3772	lysozyme
CDO22_RS08705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO22_RS08735	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS08750	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS08770	COG0110	maltose O-acetyltransferase activity
CDO22_RS08785	COG1612	heme a metabolic process
CDO22_RS08790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDO22_RS08795	COG0010	Belongs to the arginase family
CDO22_RS08800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDO22_RS08805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDO22_RS08815	COG1024	Enoyl-CoA hydratase
CDO22_RS08825	COG1832	CoA-binding protein
CDO22_RS08845	COG2124	cytochrome p450
CDO22_RS08855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO22_RS08860	COG0740	serine-type endopeptidase activity
CDO22_RS08865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDO22_RS08870	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO22_RS08875	COG0776	regulation of translation
CDO22_RS08895	COG0420	3'-5' exonuclease activity
CDO22_RS08900	COG4717	serine-type aminopeptidase activity
CDO22_RS08915	COG3328	transposase activity
CDO22_RS08935	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO22_RS08940	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO22_RS08945	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO22_RS08950	COG0649	NAD binding
CDO22_RS08960	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CDO22_RS08965	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDO22_RS08970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDO22_RS08970	COG3743	rRNA binding
CDO22_RS08980	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CDO22_RS08985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO22_RS08995	COG0713	ATP synthesis coupled electron transport
CDO22_RS09010	COG1007	ATP synthesis coupled electron transport
CDO22_RS09025	COG0346	lactoylglutathione lyase activity
CDO22_RS09050	COG0442	prolyl-tRNA aminoacylation
CDO22_RS09060	COG1136	(ABC) transporter
CDO22_RS09075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO22_RS09085	COG0784	Response regulator, receiver
CDO22_RS09095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDO22_RS09115	COG0557	exoribonuclease II activity
CDO22_RS09120	COG1754	DNA topoisomerase type I activity
CDO22_RS09120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDO22_RS09125	COG0758	DNA mediated transformation
CDO22_RS09130	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDO22_RS09135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDO22_RS09140	COG0540	Belongs to the ATCase OTCase family
CDO22_RS09145	COG1960	acyl-CoA dehydrogenase activity
CDO22_RS09165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDO22_RS09170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDO22_RS09175	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDO22_RS09180	COG0154	amidase activity
CDO22_RS09185	COG3811	Belongs to the UPF0386 family
CDO22_RS09190	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDO22_RS09210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDO22_RS09215	COG0439	Biotin carboxylase
CDO22_RS09220	COG0511	ligase activity, forming carbon-carbon bonds
CDO22_RS09225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDO22_RS09240	COG0436	Aminotransferase
CDO22_RS09280	COG1530	ribonuclease E activity
CDO22_RS09290	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO22_RS09295	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO22_RS09320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDO22_RS09340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDO22_RS09350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO22_RS09365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDO22_RS09375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS09395	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDO22_RS09400	COG0081	regulation of translation
CDO22_RS09405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDO22_RS09410	COG0222	ribosome binding
CDO22_RS09415	COG0085	RNA polymerase activity
CDO22_RS09420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDO22_RS09430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDO22_RS09435	COG0049	tRNA binding
CDO22_RS09440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDO22_RS09445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDO22_RS09450	COG0051	transcription antitermination factor activity, RNA binding
CDO22_RS09455	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDO22_RS09460	COG0088	Forms part of the polypeptide exit tunnel
CDO22_RS09465	COG0089	rRNA binding
CDO22_RS09470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDO22_RS09475	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDO22_RS09480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDO22_RS09485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDO22_RS09490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDO22_RS09495	COG0255	Belongs to the universal ribosomal protein uL29 family
CDO22_RS09500	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDO22_RS09505	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDO22_RS09510	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDO22_RS09515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDO22_RS09520	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDO22_RS09525	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDO22_RS09530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDO22_RS09535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDO22_RS09540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDO22_RS09545	COG1841	ribosomal large subunit assembly
CDO22_RS09550	COG0200	Binds to the 23S rRNA
CDO22_RS09560	COG0563	adenylate kinase activity
CDO22_RS09565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDO22_RS09570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDO22_RS09575	COG0202	RNA polymerase activity
CDO22_RS09580	COG0203	ribosomal protein L17
CDO22_RS09590	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CDO22_RS09595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO22_RS09600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO22_RS09605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDO22_RS09620	COG0546	phosphoglycolate phosphatase activity
CDO22_RS09625	COG0564	pseudouridine synthase activity
CDO22_RS09630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDO22_RS09635	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDO22_RS09645	COG1671	Belongs to the UPF0178 family
CDO22_RS09650	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDO22_RS09660	COG0321	lipoyl(octanoyl) transferase activity
CDO22_RS09670	COG2766	serine protein kinase
CDO22_RS09675	COG2718	Belongs to the UPF0229 family
CDO22_RS09680	COG2719	SpoVR family
CDO22_RS09695	COG0242	peptide deformylase activity
CDO22_RS09700	COG2239	Acts as a magnesium transporter
CDO22_RS09725	COG1760	l-serine dehydratase
CDO22_RS09775	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CDO22_RS09785	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO22_RS09795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDO22_RS09800	COG0302	gtp cyclohydrolase
CDO22_RS09810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDO22_RS09825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDO22_RS09865	COG0187	DNA topoisomerase II activity
CDO22_RS09890	COG0149	triose-phosphate isomerase activity
CDO22_RS09895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDO22_RS09900	COG0504	CTP synthase activity
CDO22_RS09910	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CDO22_RS09915	COG0148	phosphopyruvate hydratase activity
CDO22_RS09925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDO22_RS09930	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO22_RS09930	COG0022	dehydrogenase e1 component
CDO22_RS09935	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO22_RS09950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO22_RS09960	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDO22_RS09970	COG2867	negative regulation of translational initiation
CDO22_RS09975	COG1546	Belongs to the CinA family
CDO22_RS09975	COG1058	Belongs to the CinA family
CDO22_RS09980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDO22_RS09980	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDO22_RS09990	COG3852	Histidine kinase
CDO22_RS09995	COG2204	response regulator
CDO22_RS10000	COG5000	phosphorelay sensor kinase activity
CDO22_RS10005	COG2204	response regulator
CDO22_RS10010	COG0569	domain protein
CDO22_RS10015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO22_RS10020	COG1923	regulation of RNA biosynthetic process
CDO22_RS10025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDO22_RS10035	COG3956	TIGRFAM MazG family protein
CDO22_RS10045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO22_RS10045	COG1648	precorrin-2 dehydrogenase activity
CDO22_RS10055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO22_RS10075	COG1126	abc transporter atp-binding protein
CDO22_RS10080	COG0765	amino acid transport
CDO22_RS10085	COG4597	amino acid ABC transporter
CDO22_RS10090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO22_RS10095	COG0626	cystathionine gamma-synthase activity
CDO22_RS10110	COG0596	Alpha beta hydrolase
CDO22_RS10115	COG1045	serine acetyltransferase
CDO22_RS10130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDO22_RS10150	COG0537	adenosine 5'-monophosphoramidase activity
CDO22_RS10180	COG0052	Belongs to the universal ribosomal protein uS2 family
CDO22_RS10185	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDO22_RS10190	COG0528	UMP kinase activity
CDO22_RS10195	COG0233	cytoplasmic translational termination
CDO22_RS10200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDO22_RS10210	COG0750	zinc metalloprotease
CDO22_RS10220	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO22_RS10225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO22_RS10230	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO22_RS10240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO22_RS10255	COG0372	Belongs to the citrate synthase family
CDO22_RS10270	COG0848	biopolymer transport protein
CDO22_RS10275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO22_RS10290	COG0525	valine-tRNA ligase activity
CDO22_RS10300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CDO22_RS10310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO22_RS10320	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CDO22_RS10325	COG0018	arginyl-trna synthetase
CDO22_RS10335	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO22_RS10340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDO22_RS10345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDO22_RS10350	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO22_RS10355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO22_RS10360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO22_RS10365	COG0805	protein transport
CDO22_RS10370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDO22_RS10375	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CDO22_RS10380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO22_RS10400	COG1862	Preprotein translocase
CDO22_RS10425	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CDO22_RS10445	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDO22_RS10450	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDO22_RS10450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDO22_RS10455	COG0509	glycine decarboxylation via glycine cleavage system
CDO22_RS10460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO22_RS10480	COG3328	transposase activity
CDO22_RS10495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDO22_RS10505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDO22_RS10510	COG0629	single-stranded DNA binding
CDO22_RS10515	COG2095	MarC family integral membrane protein
CDO22_RS10520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDO22_RS10550	COG1902	pentaerythritol trinitrate reductase activity
CDO22_RS10560	COG0583	DNA-binding transcription factor activity
CDO22_RS10565	COG0492	ferredoxin-NADP+ reductase activity
CDO22_RS10570	COG1522	sequence-specific DNA binding
CDO22_RS10575	COG0463	Glycosyl transferase, family 2
CDO22_RS10580	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS10585	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS10590	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS10595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO22_RS10610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDO22_RS10620	COG2321	neutral zinc metallopeptidase
CDO22_RS10630	COG0534	Mate efflux family protein
CDO22_RS10640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDO22_RS10655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDO22_RS10660	COG0343	queuine tRNA-ribosyltransferase activity
CDO22_RS10670	COG0300	oxidoreductase activity
CDO22_RS10695	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS10695	COG1388	LysM domain
CDO22_RS10725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDO22_RS10740	COG2801	Transposase and inactivated derivatives
CDO22_RS10750	COG0084	hydrolase, TatD family'
CDO22_RS10755	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO22_RS10770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDO22_RS10780	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDO22_RS10820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDO22_RS11015	COG0740	serine-type endopeptidase activity
CDO22_RS11020	COG4695	Portal protein
CDO22_RS11140	COG2076	Multidrug Resistance protein
CDO22_RS11160	COG4221	oxidoreductase activity
CDO22_RS11170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDO22_RS11175	COG2897	thiosulfate sulfurtransferase activity
CDO22_RS11190	COG0686	Belongs to the AlaDH PNT family
CDO22_RS11195	COG1522	sequence-specific DNA binding
CDO22_RS11200	COG0737	Belongs to the 5'-nucleotidase family
CDO22_RS11210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO22_RS11215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDO22_RS11230	COG3795	YCII-related domain
CDO22_RS11255	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDO22_RS11260	COG1058	Belongs to the CinA family
CDO22_RS11260	COG1546	Belongs to the CinA family
CDO22_RS11265	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CDO22_RS11270	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDO22_RS11270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDO22_RS11275	COG0347	Belongs to the P(II) protein family
CDO22_RS11280	COG0174	glutamine synthetase
CDO22_RS11310	COG3119	arylsulfatase activity
CDO22_RS11345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDO22_RS11350	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDO22_RS11355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDO22_RS11365	COG3153	acetyltransferase
CDO22_RS11370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO22_RS11375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDO22_RS11385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO22_RS11390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDO22_RS11395	COG0134	indole-3-glycerol-phosphate synthase activity
CDO22_RS11400	COG0315	cyclic pyranopterin monophosphate synthase activity
CDO22_RS11405	COG0303	'Molybdopterin
CDO22_RS11415	COG1253	flavin adenine dinucleotide binding
CDO22_RS11420	COG2186	Transcriptional regulator
CDO22_RS11430	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS11435	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS11440	COG3845	ABC transporter
CDO22_RS11450	COG1183	phosphatidylcholine synthase activity
CDO22_RS11460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO22_RS11465	COG0679	Auxin Efflux Carrier
CDO22_RS11470	COG0785	Cytochrome C biogenesis protein
CDO22_RS11550	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS11560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO22_RS11570	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS11575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS11595	COG3958	Transketolase
CDO22_RS11600	COG3959	Transketolase, thiamine diphosphate binding domain
CDO22_RS11605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS11610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS11615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS11620	COG2084	Dehydrogenase
CDO22_RS11625	COG0583	DNA-binding transcription factor activity
CDO22_RS11645	COG1522	sequence-specific DNA binding
CDO22_RS11685	COG0583	DNA-binding transcription factor activity
CDO22_RS11730	COG1278	Cold shock
CDO22_RS11775	COG0436	Aminotransferase
CDO22_RS11785	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDO22_RS11790	COG1489	DNA binding
CDO22_RS11795	COG0024	Methionine aminopeptidase
CDO22_RS11800	COG2003	Belongs to the UPF0758 family
CDO22_RS11810	COG0316	Belongs to the HesB IscA family
CDO22_RS11815	COG2151	metal-sulfur cluster biosynthetic enzyme
CDO22_RS11820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDO22_RS11825	COG0719	Fe-S assembly protein
CDO22_RS11830	COG0396	ATPase activity
CDO22_RS11835	COG0719	Fe-S assembly protein
CDO22_RS11845	COG2945	thiolester hydrolase activity
CDO22_RS11855	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDO22_RS11860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDO22_RS11870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDO22_RS11875	COG2833	Protein of unknown function (DUF455)
CDO22_RS11880	COG0739	heme binding
CDO22_RS11885	COG0513	Belongs to the DEAD box helicase family
CDO22_RS11900	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDO22_RS11905	COG3608	succinylglutamate desuccinylase aspartoacylase
CDO22_RS11905	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDO22_RS11920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO22_RS11925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDO22_RS11935	COG3191	aminopeptidase activity
CDO22_RS11955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDO22_RS11985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDO22_RS11990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO22_RS12025	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDO22_RS12030	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO22_RS12035	COG0047	phosphoribosylformylglycinamidine synthase activity
CDO22_RS12050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO22_RS12060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO22_RS12080	COG2814	Major facilitator Superfamily
CDO22_RS12085	COG2814	Major facilitator Superfamily
CDO22_RS12090	COG0483	inositol monophosphate 1-phosphatase activity
CDO22_RS12095	COG0037	tRNA processing
CDO22_RS12100	COG2066	Belongs to the glutaminase family
CDO22_RS12105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDO22_RS12115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDO22_RS12120	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CDO22_RS12130	COG0538	isocitrate dehydrogenase activity
CDO22_RS12155	COG0659	secondary active sulfate transmembrane transporter activity
CDO22_RS12160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDO22_RS12165	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDO22_RS12170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO22_RS12175	COG2313	pseudouridylate synthase activity
CDO22_RS12200	COG3106	COG3106 Predicted ATPase
CDO22_RS12205	COG3768	UPF0283 membrane protein
CDO22_RS12220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDO22_RS12225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDO22_RS12240	COG0633	Ferredoxin
CDO22_RS12260	COG3328	transposase activity
CDO22_RS12265	COG2857	Cytochrome c1
CDO22_RS12265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CDO22_RS12280	COG1132	(ABC) transporter
CDO22_RS12285	COG1132	(ABC) transporter
CDO22_RS12290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDO22_RS12295	COG0431	NADPH-dependent FMN reductase
CDO22_RS12300	COG0789	Transcriptional regulator
CDO22_RS12315	COG0408	coproporphyrinogen oxidase activity
CDO22_RS12325	COG3657	addiction module killer protein
CDO22_RS12330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDO22_RS12330	COG3218	ABC-type transport auxiliary lipoprotein component
CDO22_RS12340	COG1127	ABC transporter
CDO22_RS12345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDO22_RS12350	COG4948	Mandelate Racemase Muconate Lactonizing
CDO22_RS12370	COG0281	malic enzyme
CDO22_RS12370	COG0280	phosphate acetyltransferase
CDO22_RS12375	COG2197	response regulator
CDO22_RS12390	COG0778	Nitroreductase
CDO22_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS12415	COG0823	Involved in the tonB-independent uptake of proteins
CDO22_RS12425	COG1368	sulfuric ester hydrolase activity
CDO22_RS12450	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CDO22_RS12465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDO22_RS12470	COG0546	phosphoglycolate phosphatase activity
CDO22_RS12475	COG2989	Protein conserved in bacteria
CDO22_RS12480	COG0114	fumarate hydratase activity
CDO22_RS12490	COG2267	carboxylic ester hydrolase activity
CDO22_RS12495	COG1846	Transcriptional regulator
CDO22_RS12505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDO22_RS12510	COG0697	spore germination
CDO22_RS12515	COG0746	molybdenum cofactor guanylyltransferase activity
CDO22_RS12520	COG1763	Mo-molybdopterin cofactor biosynthetic process
CDO22_RS12545	COG5425	PFAM Usg family protein
CDO22_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS12565	COG2084	Dehydrogenase
CDO22_RS12575	COG1522	sequence-specific DNA binding
CDO22_RS12580	COG1573	uracil-dna glycosylase
CDO22_RS12595	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDO22_RS12600	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDO22_RS12605	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CDO22_RS12620	COG0842	Transport permease protein
CDO22_RS12625	COG1131	(ABC) transporter
CDO22_RS12630	COG0640	Transcriptional regulator
CDO22_RS12685	COG0556	nucleotide-excision repair
CDO22_RS12695	COG0484	heat shock protein binding
CDO22_RS12715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDO22_RS12745	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO22_RS12755	COG0735	belongs to the Fur family
CDO22_RS12760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO22_RS12765	COG1121	(ABC) transporter
CDO22_RS12780	COG3507	Belongs to the glycosyl hydrolase 43 family
CDO22_RS12790	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS12795	COG3415	Transposase
CDO22_RS12795	COG2801	Transposase and inactivated derivatives
CDO22_RS12805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CDO22_RS12810	COG0667	Aldo Keto reductase
CDO22_RS12825	COG3250	beta-galactosidase activity
CDO22_RS12830	COG3842	ATPase activity
CDO22_RS12835	COG0395	ABC-type sugar transport system, permease component
CDO22_RS12840	COG1175	transmembrane transport
CDO22_RS12860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDO22_RS12865	COG1115	amino acid carrier protein
CDO22_RS12890	COG1560	Kdo2-lipid A biosynthetic process
CDO22_RS12900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO22_RS12910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO22_RS12915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO22_RS12920	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDO22_RS12930	COG1797	cobyrinic acid a,c-diamide synthase activity
CDO22_RS12950	COG4172	Belongs to the ABC transporter superfamily
CDO22_RS12960	COG0747	negative chemotaxis
CDO22_RS12965	COG0601	transmembrane transport
CDO22_RS12970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS13015	COG0596	Alpha beta hydrolase
CDO22_RS13020	COG1492	cobalamin metabolic process
CDO22_RS13035	COG0517	IMP dehydrogenase activity
CDO22_RS13035	COG4175	Glycine betaine
CDO22_RS13040	COG3609	addiction module antidote protein, CC2985 family
CDO22_RS13055	COG0583	DNA-binding transcription factor activity
CDO22_RS13060	COG0646	methionine synthase
CDO22_RS13060	COG1410	methionine synthase
CDO22_RS13080	COG3698	Phosphodiester glycosidase
CDO22_RS13090	COG5598	trimethylamine methyltransferase
CDO22_RS13095	COG5012	cobalamin binding
CDO22_RS13110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO22_RS13145	COG1410	methionine synthase
CDO22_RS13145	COG0646	methionine synthase
CDO22_RS13170	COG0640	Transcriptional regulator
CDO22_RS13175	COG0583	DNA-binding transcription factor activity
CDO22_RS13215	COG0745	RESPONSE REGULATOR receiver
CDO22_RS13250	COG1484	DNA-dependent DNA replication
CDO22_RS13265	COG0861	Integral membrane protein TerC family
CDO22_RS13270	COG3264	Mechanosensitive ion channel
CDO22_RS13270	COG1196	nuclear chromosome segregation
CDO22_RS13285	COG3273	potassium ion transport
CDO22_RS13285	COG0471	metal ion transport
CDO22_RS13320	COG0463	Glycosyl transferase, family 2
CDO22_RS13445	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CDO22_RS13450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO22_RS13550	COG0384	phenazine biosynthesis protein PhzF
CDO22_RS13590	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CDO22_RS13605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDO22_RS13620	COG3842	ATPase activity
CDO22_RS13625	COG4149	molybdate abc transporter
CDO22_RS13635	COG3328	transposase activity
CDO22_RS13650	COG1278	Cold shock
CDO22_RS13660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDO22_RS13670	COG0667	Aldo Keto reductase
CDO22_RS13675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO22_RS13685	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS13705	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDO22_RS13715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO22_RS13720	COG0577	efflux transmembrane transporter activity
CDO22_RS13720	COG1136	(ABC) transporter
CDO22_RS13750	COG2271	Major facilitator Superfamily
CDO22_RS13760	COG1737	Transcriptional regulator
CDO22_RS13765	COG1252	NADH dehydrogenase
CDO22_RS13770	COG1522	sequence-specific DNA binding
CDO22_RS13775	COG1794	racemase activity, acting on amino acids and derivatives
CDO22_RS13780	COG1733	regulation of RNA biosynthetic process
CDO22_RS13795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO22_RS13800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDO22_RS13845	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO22_RS13845	COG1672	PFAM Archaeal ATPase
CDO22_RS13850	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO22_RS13855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDO22_RS13860	COG3180	Ammonia monooxygenase
CDO22_RS13880	COG1595	DNA-templated transcription, initiation
CDO22_RS13920	COG1278	Cold shock
CDO22_RS13925	COG0656	L-ascorbic acid biosynthetic process
CDO22_RS13930	COG0440	acetolactate synthase activity
CDO22_RS13935	COG0028	Belongs to the TPP enzyme family
CDO22_RS13955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDO22_RS13960	COG3830	Belongs to the UPF0237 family
CDO22_RS13960	COG0560	Phosphoserine phosphatase
CDO22_RS13965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO22_RS13970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO22_RS13985	COG0330	HflC and HflK could
CDO22_RS14005	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDO22_RS14060	COG3385	transposase activity
CDO22_RS14070	COG0277	FAD linked oxidase domain protein
CDO22_RS14080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO22_RS14115	COG3706	GGDEF domain
CDO22_RS14135	COG0835	chemotaxis
CDO22_RS14140	COG0840	transmembrane signaling receptor activity
CDO22_RS14150	COG1999	signal sequence binding
CDO22_RS14155	COG2264	protein methyltransferase activity
CDO22_RS14175	COG0006	proline dipeptidase activity
CDO22_RS14195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO22_RS14200	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDO22_RS14210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDO22_RS14220	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO22_RS14230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDO22_RS14235	COG0849	cell division
CDO22_RS14240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDO22_RS14245	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO22_RS14250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDO22_RS14255	COG0477	Major facilitator Superfamily
CDO22_RS14260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDO22_RS14265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDO22_RS14270	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDO22_RS14280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDO22_RS14285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDO22_RS14295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDO22_RS14310	COG0275	rRNA processing
CDO22_RS14315	COG2001	Belongs to the MraZ family
CDO22_RS14335	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDO22_RS14340	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CDO22_RS14350	COG1280	lysine exporter protein (LysE YggA)
CDO22_RS14410	COG3719	Belongs to the RNase T2 family
CDO22_RS14415	COG2267	carboxylic ester hydrolase activity
CDO22_RS14425	COG0028	Belongs to the TPP enzyme family
CDO22_RS14445	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS14450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS14465	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS14470	COG0174	glutamine synthetase
CDO22_RS14505	COG3842	ATPase activity
CDO22_RS14510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDO22_RS14520	COG4774	siderophore transport
CDO22_RS14525	COG3328	transposase activity
CDO22_RS14535	COG0149	triose-phosphate isomerase activity
CDO22_RS14540	COG1349	DNA-binding transcription factor activity
CDO22_RS14555	COG1070	Carbohydrate kinase
CDO22_RS14570	COG0235	Class ii aldolase
CDO22_RS14590	COG3842	ATPase activity
CDO22_RS14600	COG1175	transmembrane transport
CDO22_RS14605	COG1653	transport
CDO22_RS14615	COG2197	response regulator
CDO22_RS14620	COG3842	ATPase activity
CDO22_RS14635	COG1177	transmembrane transport
CDO22_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS14650	COG3246	L-lysine catabolic process to acetate
CDO22_RS14655	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO22_RS14655	COG0824	Thioesterase
CDO22_RS14660	COG1960	acyl-CoA dehydrogenase activity
CDO22_RS14680	COG0747	negative chemotaxis
CDO22_RS14690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS14725	COG0583	DNA-binding transcription factor activity
CDO22_RS14730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CDO22_RS14735	COG3842	ATPase activity
CDO22_RS14740	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO22_RS14745	COG1177	transmembrane transport
CDO22_RS14750	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS14815	COG1024	Enoyl-CoA hydratase
CDO22_RS14935	COG1696	Membrane protein involved in D-alanine export
CDO22_RS14970	COG2968	Membrane
CDO22_RS14985	COG0432	Pfam Uncharacterised protein family UPF0047
CDO22_RS14990	COG5507	3-demethylubiquinone-9 3-methyltransferase
CDO22_RS15010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO22_RS15015	COG1063	alcohol dehydrogenase
CDO22_RS15025	COG0514	ATP-dependent DNA helicase (RecQ)
CDO22_RS15030	COG0358	DNA primase activity
CDO22_RS15040	COG0505	Belongs to the CarA family
CDO22_RS15050	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS15055	COG2084	Dehydrogenase
CDO22_RS15065	COG0436	Aminotransferase
CDO22_RS15080	COG2133	pyrroloquinoline quinone binding
CDO22_RS15090	COG1278	Cold shock
CDO22_RS15100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO22_RS15120	COG1846	Transcriptional regulator
CDO22_RS15125	COG0745	RESPONSE REGULATOR receiver
CDO22_RS15130	COG2205	protein histidine kinase activity
CDO22_RS15135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO22_RS15155	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDO22_RS15165	COG1496	oxidoreductase activity
CDO22_RS15180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDO22_RS15185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CDO22_RS15195	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS15205	COG3135	benzoate transporter
CDO22_RS15210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDO22_RS15215	COG0193	aminoacyl-tRNA hydrolase activity
CDO22_RS15220	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDO22_RS15240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDO22_RS15265	COG0714	Associated with various cellular activities
CDO22_RS15290	COG0435	Glutathione S-transferase
CDO22_RS15315	COG1595	DNA-templated transcription, initiation
CDO22_RS15325	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
CDO22_RS15330	COG4423	Transcription factor
CDO22_RS15335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDO22_RS15345	COG0740	serine-type endopeptidase activity
CDO22_RS15360	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDO22_RS15365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDO22_RS15370	COG0512	Glutamine amidotransferase of anthranilate synthase
CDO22_RS15370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO22_RS15385	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDO22_RS15400	COG3385	transposase activity
CDO22_RS15405	COG2852	Protein conserved in bacteria
CDO22_RS15425	COG1435	thymidine kinase activity
CDO22_RS15460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO22_RS15465	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO22_RS15470	COG0366	Alpha amylase catalytic
CDO22_RS15475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO22_RS15480	COG3328	transposase activity
CDO22_RS15485	COG4608	Belongs to the ABC transporter superfamily
CDO22_RS15490	COG0444	Belongs to the ABC transporter superfamily
CDO22_RS15495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS15500	COG0601	transmembrane transport
CDO22_RS15515	COG2076	Multidrug Resistance protein
CDO22_RS15535	COG2346	COG2346, Truncated hemoglobins
CDO22_RS15585	COG4558	Periplasmic binding protein
CDO22_RS15590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO22_RS15595	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CDO22_RS15610	COG2202	Pas domain
CDO22_RS15610	COG3920	Histidine kinase
CDO22_RS15625	COG0784	Response regulator, receiver
CDO22_RS15655	COG0395	ABC-type sugar transport system, permease component
CDO22_RS15660	COG1175	transmembrane transport
CDO22_RS15685	COG1063	alcohol dehydrogenase
CDO22_RS15690	COG0583	DNA-binding transcription factor activity
CDO22_RS15705	COG1309	transcriptional regulator
CDO22_RS15735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO22_RS15740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO22_RS15745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO22_RS15760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CDO22_RS15765	COG0830	nickel cation binding
CDO22_RS15770	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CDO22_RS15800	COG0804	urea catabolic process
CDO22_RS15805	COG1442	glycosyl transferase family 8
CDO22_RS15810	COG3755	Protein conserved in bacteria
CDO22_RS15815	COG0832	Belongs to the urease beta subunit family
CDO22_RS15820	COG3813	Protein conserved in bacteria
CDO22_RS15825	COG0831	urea catabolic process
CDO22_RS15830	COG0829	nickel cation binding
CDO22_RS15835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO22_RS15845	COG1846	Transcriptional regulator
CDO22_RS15885	COG0784	Response regulator, receiver
CDO22_RS15890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO22_RS15900	COG0400	carboxylic ester hydrolase activity
CDO22_RS15930	COG0346	lactoylglutathione lyase activity
CDO22_RS15935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO22_RS15945	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO22_RS15950	COG3842	ATPase activity
CDO22_RS15970	COG0436	Aminotransferase
CDO22_RS15990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS15995	COG0174	glutamine synthetase
CDO22_RS16005	COG1725	Transcriptional regulator
CDO22_RS16010	COG0626	cystathionine gamma-synthase activity
CDO22_RS16025	COG0395	ABC-type sugar transport system, permease component
CDO22_RS16030	COG3842	ATPase activity
CDO22_RS16040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO22_RS16045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO22_RS16050	COG1845	cytochrome c oxidase, subunit III
CDO22_RS16090	COG1063	alcohol dehydrogenase
CDO22_RS16115	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS16120	COG1129	ABC transporter
CDO22_RS16155	COG1473	amidohydrolase
CDO22_RS16180	COG0601	transmembrane transport
CDO22_RS16185	COG0583	DNA-binding transcription factor activity
CDO22_RS16190	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS16200	COG1129	ABC transporter
CDO22_RS16215	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS16225	COG1802	Transcriptional regulator
CDO22_RS16230	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS16240	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS16245	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS16250	COG2140	Oxalate decarboxylase
CDO22_RS16255	COG0800	Aldolase
CDO22_RS16265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO22_RS16270	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDO22_RS16275	COG1737	Transcriptional regulator
CDO22_RS16280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDO22_RS16295	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS16300	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS16305	COG1129	ABC transporter
CDO22_RS16310	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS16315	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS16320	COG2188	Transcriptional regulator
CDO22_RS16325	COG1070	Carbohydrate kinase
CDO22_RS16330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO22_RS16335	COG0477	Major facilitator Superfamily
CDO22_RS16375	COG0174	glutamine synthetase
CDO22_RS16390	COG1335	isochorismatase
CDO22_RS16395	COG0683	leucine binding
CDO22_RS16420	COG1335	isochorismatase
CDO22_RS16430	COG0402	S-adenosylhomocysteine deaminase activity
CDO22_RS16450	COG0601	transmembrane transport
CDO22_RS16455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS16465	COG1228	amidohydrolase
CDO22_RS16470	COG0444	Belongs to the ABC transporter superfamily
CDO22_RS16475	COG4608	Belongs to the ABC transporter superfamily
CDO22_RS16480	COG1802	Transcriptional regulator
CDO22_RS16495	COG0723	plastoquinol--plastocyanin reductase activity
CDO22_RS16500	COG0583	DNA-binding transcription factor activity
CDO22_RS16505	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO22_RS16545	COG0739	heme binding
CDO22_RS16550	COG0542	response to heat
CDO22_RS16565	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO22_RS16570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDO22_RS16575	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CDO22_RS16580	COG0527	aspartate kinase activity
CDO22_RS16590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDO22_RS16600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO22_RS16615	COG2226	methyltransferase
CDO22_RS16630	COG0494	nUDIX hydrolase
CDO22_RS16640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDO22_RS16645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO22_RS16650	COG0653	protein targeting
CDO22_RS16670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO22_RS16705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDO22_RS16715	COG0300	oxidoreductase activity
CDO22_RS16725	COG2096	Adenosyltransferase
CDO22_RS16735	COG2086	electron transfer activity
CDO22_RS16740	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDO22_RS16745	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO22_RS16750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO22_RS16755	COG0165	Argininosuccinate lyase
CDO22_RS16775	COG3385	transposase activity
CDO22_RS16795	COG2884	Cell division ATP-binding protein ftsE
CDO22_RS16815	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CDO22_RS16825	COG0287	Prephenate dehydrogenase
CDO22_RS16830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO22_RS16835	COG2226	methyltransferase
CDO22_RS16840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO22_RS16860	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDO22_RS16865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CDO22_RS16895	COG4536	flavin adenine dinucleotide binding
CDO22_RS16900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDO22_RS16905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDO22_RS16915	COG3609	addiction module antidote protein, CC2985 family
CDO22_RS16925	COG4974	Belongs to the 'phage' integrase family
CDO22_RS16930	COG0825	malonyl-CoA metabolic process
CDO22_RS16935	COG3034	peptidoglycan biosynthetic process
CDO22_RS16955	COG0523	cobalamin synthesis protein
CDO22_RS16960	COG1686	Belongs to the peptidase S11 family
CDO22_RS16965	COG1473	amidohydrolase
CDO22_RS16975	COG1064	alcohol dehydrogenase
CDO22_RS16980	COG2207	Transcriptional regulator
CDO22_RS16985	COG1522	sequence-specific DNA binding
CDO22_RS16990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO22_RS16995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO22_RS17000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO22_RS17010	COG0402	S-adenosylhomocysteine deaminase activity
CDO22_RS17020	COG4176	ABC-type proline glycine betaine transport system permease component
CDO22_RS17025	COG4175	Glycine betaine
CDO22_RS17025	COG0517	IMP dehydrogenase activity
CDO22_RS17030	COG2986	histidine ammonia-lyase
CDO22_RS17035	COG3314	Sporulation integral membrane protein YlbJ
CDO22_RS17090	COG0482	sulfurtransferase activity
CDO22_RS17150	COG0564	pseudouridine synthase activity
CDO22_RS17155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO22_RS17165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDO22_RS17175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO22_RS17200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDO22_RS17205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDO22_RS17210	COG0037	tRNA processing
CDO22_RS17220	COG2885	chlorophyll binding
CDO22_RS17225	COG0823	Involved in the tonB-independent uptake of proteins
CDO22_RS17250	COG0824	Thioesterase
CDO22_RS17270	COG1408	metallophosphoesterase
CDO22_RS17275	COG2255	four-way junction helicase activity
CDO22_RS17280	COG0632	four-way junction helicase activity
CDO22_RS17285	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDO22_RS17290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO22_RS17295	COG0217	transcriptional regulatory protein
CDO22_RS17310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO22_RS17315	COG1692	metallophosphoesterase
CDO22_RS17365	COG0126	phosphoglycerate kinase activity
CDO22_RS17370	COG3328	transposase activity
CDO22_RS17375	COG3588	fructose-bisphosphate aldolase
CDO22_RS17380	COG0384	phenazine biosynthesis protein PhzF
CDO22_RS17410	COG0254	rRNA binding
CDO22_RS17415	COG1132	(ABC) transporter
CDO22_RS17430	COG0483	inositol monophosphate 1-phosphatase activity
CDO22_RS17450	COG0640	Transcriptional regulator
CDO22_RS17465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDO22_RS17470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDO22_RS17475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDO22_RS17480	COG0457	Tetratricopeptide repeat
CDO22_RS17485	COG0469	pyruvate kinase activity
CDO22_RS17505	COG3750	Belongs to the UPF0335 family
CDO22_RS17510	COG3108	Peptidase M15
CDO22_RS17515	COG2204	response regulator
CDO22_RS17525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO22_RS17540	COG5310	Homospermidine synthase
CDO22_RS17550	COG0737	Belongs to the 5'-nucleotidase family
CDO22_RS17555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDO22_RS17560	COG0330	HflC and HflK could
CDO22_RS17565	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDO22_RS17575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO22_RS17580	COG2951	lytic endotransglycosylase activity
CDO22_RS17595	COG0067	glutamate synthase
CDO22_RS17595	COG0070	glutamate synthase
CDO22_RS17595	COG0069	glutamate synthase activity
CDO22_RS17615	COG2197	response regulator
CDO22_RS17620	COG2267	carboxylic ester hydrolase activity
CDO22_RS17625	COG0601	transmembrane transport
CDO22_RS17630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS17635	COG4172	Belongs to the ABC transporter superfamily
CDO22_RS17645	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO22_RS17680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO22_RS17700	COG3772	lysozyme
CDO22_RS17820	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDO22_RS17875	COG0328	RNA-DNA hybrid ribonuclease activity
CDO22_RS17930	COG4712	double-strand break repair protein
CDO22_RS17935	COG0629	single-stranded DNA binding
CDO22_RS17980	COG0129	dihydroxy-acid dehydratase activity
CDO22_RS18040	COG0583	DNA-binding transcription factor activity
CDO22_RS18045	COG0667	Aldo Keto reductase
CDO22_RS18055	COG1305	Transglutaminase-like
CDO22_RS18065	COG0058	SHG alpha-glucan phosphorylase activity
CDO22_RS18070	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDO22_RS18075	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDO22_RS18080	COG0297	glycogen (starch) synthase activity
CDO22_RS18085	COG0033	Phosphoglucomutase
CDO22_RS18095	COG1523	belongs to the glycosyl hydrolase 13 family
CDO22_RS18120	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO22_RS18120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO22_RS18130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS18140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDO22_RS18215	COG2207	Transcriptional regulator
CDO22_RS18230	COG1335	isochorismatase
CDO22_RS18240	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CDO22_RS18250	COG2814	Major facilitator Superfamily
CDO22_RS18255	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO22_RS18330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO22_RS18330	COG1672	PFAM Archaeal ATPase
CDO22_RS18380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO22_RS18390	COG1802	Transcriptional regulator
CDO22_RS18395	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS18405	COG3842	ATPase activity
CDO22_RS18410	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO22_RS18415	COG1177	transmembrane transport
CDO22_RS18445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO22_RS18450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO22_RS18455	COG1120	ATPase activity
CDO22_RS18480	COG0583	DNA-binding transcription factor activity
CDO22_RS18515	COG1309	transcriptional regulator
CDO22_RS18525	COG1335	isochorismatase
CDO22_RS18535	COG0583	DNA-binding transcription factor activity
CDO22_RS18545	COG2252	PERMEase
CDO22_RS18620	COG4191	Histidine kinase
CDO22_RS18625	COG3119	arylsulfatase activity
CDO22_RS18660	COG0471	metal ion transport
CDO22_RS18660	COG0490	domain, Protein
CDO22_RS18665	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDO22_RS18670	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDO22_RS18735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS18740	COG0444	Belongs to the ABC transporter superfamily
CDO22_RS18775	COG0583	DNA-binding transcription factor activity
CDO22_RS18785	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS18810	COG1902	pentaerythritol trinitrate reductase activity
CDO22_RS18820	COG4651	solute:proton antiporter activity
CDO22_RS18820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO22_RS18840	COG0723	plastoquinol--plastocyanin reductase activity
CDO22_RS18845	COG1672	PFAM Archaeal ATPase
CDO22_RS18845	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO22_RS18850	COG3177	Filamentation induced by cAMP protein fic
CDO22_RS18890	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CDO22_RS18890	COG3264	Mechanosensitive ion channel
CDO22_RS18915	COG0489	protein tyrosine kinase activity
CDO22_RS18955	COG0840	transmembrane signaling receptor activity
CDO22_RS18975	COG5001	Diguanylate cyclase
CDO22_RS18980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO22_RS18985	COG0839	Belongs to the complex I subunit 6 family
CDO22_RS18995	COG0651	ATP synthesis coupled electron transport
CDO22_RS19005	COG0651	ATP synthesis coupled electron transport
CDO22_RS19075	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS19080	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS19085	COG3845	ABC transporter
CDO22_RS19095	COG1802	Transcriptional regulator
CDO22_RS19115	COG0625	glutathione transferase activity
CDO22_RS19120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO22_RS19170	COG5598	trimethylamine methyltransferase
CDO22_RS19180	COG0006	proline dipeptidase activity
CDO22_RS19185	COG1335	isochorismatase
CDO22_RS19210	COG4948	Mandelate Racemase Muconate Lactonizing
CDO22_RS19240	COG0183	Belongs to the thiolase family
CDO22_RS19250	COG0477	Major facilitator Superfamily
CDO22_RS19260	COG2186	Transcriptional regulator
CDO22_RS19270	COG0747	negative chemotaxis
CDO22_RS19275	COG0601	transmembrane transport
CDO22_RS19280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS19285	COG4172	Belongs to the ABC transporter superfamily
CDO22_RS19310	COG0747	negative chemotaxis
CDO22_RS19320	COG0154	amidase activity
CDO22_RS19330	COG0601	transmembrane transport
CDO22_RS19335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS19340	COG0444	Belongs to the ABC transporter superfamily
CDO22_RS19345	COG4608	Belongs to the ABC transporter superfamily
CDO22_RS19360	COG0444	Belongs to the ABC transporter superfamily
CDO22_RS19380	COG1175	transmembrane transport
CDO22_RS19385	COG0395	ABC-type sugar transport system, permease component
CDO22_RS19400	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO22_RS19420	COG1082	Xylose isomerase domain protein TIM barrel
CDO22_RS19425	COG1082	Xylose isomerase domain protein TIM barrel
CDO22_RS19430	COG4948	Mandelate Racemase Muconate Lactonizing
CDO22_RS19440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO22_RS19445	COG3842	ATPase activity
CDO22_RS19450	COG3842	ATPase activity
CDO22_RS19465	COG1175	transmembrane transport
CDO22_RS19485	COG5564	TIM-barrel signal transduction protein
CDO22_RS19495	COG0024	Methionine aminopeptidase
CDO22_RS19500	COG0477	Major facilitator Superfamily
CDO22_RS19535	COG3838	Conjugal transfer protein Trbc
CDO22_RS19540	COG3702	type iv secretory pathway
CDO22_RS19545	COG3451	type IV secretory pathway VirB4
CDO22_RS19560	COG3704	protein secretion by the type IV secretion system
CDO22_RS19570	COG3736	Type IV secretory pathway, component VirB8
CDO22_RS19575	COG3504	Conjugal transfer protein
CDO22_RS19580	COG2948	multi-organism process
CDO22_RS19585	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CDO22_RS19590	COG2814	Major facilitator Superfamily
CDO22_RS19595	COG1309	transcriptional regulator
CDO22_RS19620	COG0826	peptidase U32
CDO22_RS19625	COG0826	peptidase U32
CDO22_RS19635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CDO22_RS19660	COG1845	cytochrome c oxidase, subunit III
CDO22_RS19675	COG3256	nitric oxide reductase
CDO22_RS19680	COG0714	Associated with various cellular activities
CDO22_RS19690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDO22_RS19720	COG2151	metal-sulfur cluster biosynthetic enzyme
CDO22_RS19745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO22_RS19755	COG4459	periplasmic nitrate reductase
CDO22_RS19780	COG3005	denitrification pathway
CDO22_RS19965	COG0583	DNA-binding transcription factor activity
CDO22_RS19985	COG0667	Aldo Keto reductase
CDO22_RS19990	COG0583	DNA-binding transcription factor activity
CDO22_RS20040	COG2801	Transposase and inactivated derivatives
CDO22_RS20060	COG0583	DNA-binding transcription factor activity
CDO22_RS20120	COG0601	transmembrane transport
CDO22_RS20125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS20135	COG2843	Capsule synthesis protein
CDO22_RS20140	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDO22_RS20150	COG3119	arylsulfatase activity
CDO22_RS20160	COG4566	intracellular signal transduction
CDO22_RS20190	COG0668	transmembrane transport
CDO22_RS20210	COG3505	Type IV secretory pathway VirD4
CDO22_RS20285	COG3012	SEC-C Motif Domain Protein
CDO22_RS20315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO22_RS20350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO22_RS20420	COG2895	sulfate adenylyltransferase (ATP) activity
CDO22_RS20420	COG0529	Catalyzes the synthesis of activated sulfate
CDO22_RS20425	COG0175	sulfate reduction
CDO22_RS20460	COG3328	transposase activity
CDO22_RS20510	COG3383	formate dehydrogenase (NAD+) activity
CDO22_RS20515	COG5420	small protein containing a coiled-coil domain
CDO22_RS20520	COG1433	Dinitrogenase iron-molybdenum cofactor
CDO22_RS20530	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDO22_RS20535	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDO22_RS20550	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO22_RS20615	COG4372	Transposase
CDO22_RS20620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDO22_RS20635	COG2433	Pfam Transposase IS66
CDO22_RS20665	COG0395	ABC-type sugar transport system, permease component
CDO22_RS20685	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS20690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO22_RS20700	COG2267	carboxylic ester hydrolase activity
CDO22_RS20710	COG3328	transposase activity
CDO22_RS20720	COG3328	transposase activity
CDO22_RS20765	COG2010	Cytochrome c
CDO22_RS20830	COG3831	ATPase activity
CDO22_RS20855	COG3328	transposase activity
CDO22_RS20875	COG3505	Type IV secretory pathway VirD4
CDO22_RS20880	COG0745	RESPONSE REGULATOR receiver
CDO22_RS20900	COG4372	Transposase
CDO22_RS21025	COG4638	Rieske (2fe-2S)
CDO22_RS21030	COG0583	DNA-binding transcription factor activity
CDO22_RS21070	COG1082	Xylose isomerase domain protein TIM barrel
CDO22_RS21085	COG3961	Belongs to the TPP enzyme family
CDO22_RS21105	COG4372	Transposase
CDO22_RS21120	COG0492	ferredoxin-NADP+ reductase activity
CDO22_RS21125	COG2226	methyltransferase
CDO22_RS21130	COG2124	cytochrome p450
CDO22_RS21155	COG1115	amino acid carrier protein
CDO22_RS21175	COG1278	Cold shock
CDO22_RS21285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO22_RS21300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO22_RS21315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO22_RS21320	COG3344	reverse transcriptase
CDO22_RS21350	COG1396	sequence-specific DNA binding
CDO22_RS21370	COG0464	growth
CDO22_RS21410	COG1115	amino acid carrier protein
CDO22_RS21435	COG1278	Cold shock
CDO22_RS21550	COG4584	PFAM Integrase catalytic
CDO22_RS21555	COG1484	DNA-dependent DNA replication
CDO22_RS21580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO22_RS21590	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDO22_RS21600	COG1454	alcohol dehydrogenase
CDO22_RS21670	COG3328	transposase activity
CDO22_RS21680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDO22_RS21690	COG1454	alcohol dehydrogenase
CDO22_RS21700	COG1414	Transcriptional regulator
CDO22_RS21710	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS21720	COG3842	ATPase activity
CDO22_RS21810	COG1396	sequence-specific DNA binding
CDO22_RS21905	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDO22_RS21915	COG1454	alcohol dehydrogenase
CDO22_RS21935	COG1192	Involved in chromosome partitioning
CDO22_RS21955	COG5433	transposase activity
CDO22_RS21970	COG3328	transposase activity
CDO22_RS21985	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO22_RS22005	COG2086	electron transfer activity
CDO22_RS22050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO22_RS22125	COG4372	Transposase
CDO22_RS22135	COG2963	transposase activity
CDO22_RS22185	COG1349	DNA-binding transcription factor activity
CDO22_RS22210	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS22220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS22235	COG0395	ABC-type sugar transport system, permease component
CDO22_RS22240	COG1175	transmembrane transport
CDO22_RS22245	COG1653	transport
CDO22_RS22250	COG4948	Mandelate Racemase Muconate Lactonizing
CDO22_RS22260	COG3734	2-keto-3-deoxy-galactonokinase
CDO22_RS22265	COG0837	glucose binding
CDO22_RS22315	COG0531	amino acid
CDO22_RS22330	COG1982	Orn Lys Arg decarboxylase major
CDO22_RS22335	COG0531	amino acid
CDO22_RS22370	COG0628	permease
CDO22_RS22470	COG4634	DNA integration
CDO22_RS22495	COG3179	chitinase
CDO22_RS22515	COG4302	ethanolamine ammonia-lyase activity
CDO22_RS22525	COG3459	Glycosyltransferase 36 associated
CDO22_RS22530	COG0406	alpha-ribazole phosphatase activity
CDO22_RS22535	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CDO22_RS22545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDO22_RS22545	COG0517	IMP dehydrogenase activity
CDO22_RS22545	COG0617	tRNA 3'-terminal CCA addition
CDO22_RS22560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDO22_RS22605	COG0668	transmembrane transport
CDO22_RS22625	COG2885	chlorophyll binding
CDO22_RS22625	COG3047	cAMP biosynthetic process
CDO22_RS22660	COG2010	Cytochrome c
CDO22_RS22675	COG3278	Belongs to the heme-copper respiratory oxidase family
CDO22_RS22730	COG0625	glutathione transferase activity
CDO22_RS22760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO22_RS22795	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO22_RS22800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO22_RS22810	COG1116	anion transmembrane transporter activity
CDO22_RS22830	COG2826	transposase and inactivated derivatives, IS30 family
CDO22_RS22880	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CDO22_RS22885	COG3920	Histidine kinase
CDO22_RS22900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDO22_RS22925	COG0667	Aldo Keto reductase
CDO22_RS22940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS22955	COG1960	acyl-CoA dehydrogenase activity
CDO22_RS22965	COG0702	epimerase
CDO22_RS22970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO22_RS22975	COG2910	NAD(P)H-binding
CDO22_RS22980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO22_RS22990	COG3177	Filamentation induced by cAMP protein fic
CDO22_RS23010	COG1484	DNA-dependent DNA replication
CDO22_RS23035	COG3077	Addiction module antitoxin, RelB DinJ family
CDO22_RS23040	COG0583	DNA-binding transcription factor activity
CDO22_RS23065	COG1473	amidohydrolase
CDO22_RS23070	COG4608	Belongs to the ABC transporter superfamily
CDO22_RS23075	COG0444	Belongs to the ABC transporter superfamily
CDO22_RS23080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS23085	COG0601	transmembrane transport
CDO22_RS23140	COG2442	InterPro IPR007367
CDO22_RS23190	COG0693	protein deglycase activity
CDO22_RS23195	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS23200	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS23205	COG1129	ABC transporter
CDO22_RS23210	COG1802	Transcriptional regulator
CDO22_RS23215	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CDO22_RS23220	COG1454	alcohol dehydrogenase
CDO22_RS23230	COG0657	acetylesterase activity
CDO22_RS23270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS23275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS23280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO22_RS23290	COG2186	Transcriptional regulator
CDO22_RS23295	COG0277	FAD linked oxidase domain protein
CDO22_RS23300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS23305	COG2084	Dehydrogenase
CDO22_RS23310	COG0129	dihydroxy-acid dehydratase activity
CDO22_RS23315	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CDO22_RS23325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO22_RS23335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDO22_RS23355	COG1802	Transcriptional regulator
CDO22_RS23360	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS23375	COG1129	ABC transporter
CDO22_RS23405	COG4585	Histidine kinase
CDO22_RS23410	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS23415	COG1129	ABC transporter
CDO22_RS23420	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS23465	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS23470	COG0477	Major facilitator Superfamily
CDO22_RS23475	COG1278	Cold shock
CDO22_RS23485	COG0583	DNA-binding transcription factor activity
CDO22_RS23520	COG4106	trans-aconitate 2-methyltransferase activity
CDO22_RS23540	COG4964	Belongs to the GSP D family
CDO22_RS23545	COG1802	Transcriptional regulator
CDO22_RS23550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS23570	COG0318	PFAM AMP-dependent synthetase and ligase
CDO22_RS23575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO22_RS23600	COG1404	Belongs to the peptidase S8 family
CDO22_RS23610	COG5001	Diguanylate cyclase
CDO22_RS23610	COG3300	MHYT domain
CDO22_RS23615	COG0628	permease
CDO22_RS23635	COG3239	Fatty acid desaturase
CDO22_RS23645	COG1278	Cold shock
CDO22_RS23705	COG1487	ribonuclease activity
CDO22_RS23710	COG4691	Plasmid stability protein
CDO22_RS23720	COG0444	Belongs to the ABC transporter superfamily
CDO22_RS23725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS23730	COG0601	transmembrane transport
CDO22_RS23735	COG0747	negative chemotaxis
CDO22_RS23740	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO22_RS23745	COG0583	DNA-binding transcription factor activity
CDO22_RS23765	COG0251	oxidation-reduction process
CDO22_RS23775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO22_RS23780	COG1126	abc transporter atp-binding protein
CDO22_RS23785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO22_RS23790	COG0765	amino acid transport
CDO22_RS23795	COG0765	amino acid transport
CDO22_RS23800	COG1609	Transcriptional regulator
CDO22_RS23830	COG1802	Transcriptional regulator
CDO22_RS23840	COG2186	Transcriptional regulator
CDO22_RS23855	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS23865	COG4948	Mandelate Racemase Muconate Lactonizing
CDO22_RS23870	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS23875	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS23900	COG0583	DNA-binding transcription factor activity
CDO22_RS23905	COG0488	(ABC) transporter
CDO22_RS23930	COG1305	Transglutaminase-like
CDO22_RS23990	COG2864	formate dehydrogenase
CDO22_RS23995	COG0437	4 iron, 4 sulfur cluster binding
CDO22_RS24005	COG1192	Involved in chromosome partitioning
CDO22_RS24010	COG1475	DNA binding
CDO22_RS24015	COG1414	Transcriptional regulator
CDO22_RS24020	COG1764	response to oxidative stress
CDO22_RS24030	COG0488	(ABC) transporter
CDO22_RS24040	COG1309	transcriptional regulator
CDO22_RS24065	COG0402	S-adenosylhomocysteine deaminase activity
CDO22_RS24070	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS24075	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS24080	COG3845	ABC transporter
CDO22_RS24095	COG0730	response to heat
CDO22_RS24125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS24130	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO22_RS24135	COG2080	2 iron, 2 sulfur cluster binding
CDO22_RS24155	COG4221	oxidoreductase activity
CDO22_RS24240	COG2205	protein histidine kinase activity
CDO22_RS24285	COG0395	ABC-type sugar transport system, permease component
CDO22_RS24305	COG4251	negative regulation of phosphorylation
CDO22_RS24305	COG5001	Diguanylate cyclase
CDO22_RS24305	COG3706	GGDEF domain
CDO22_RS24305	COG2203	Gaf domain
CDO22_RS24330	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO22_RS24340	COG1902	pentaerythritol trinitrate reductase activity
CDO22_RS24345	COG0251	oxidation-reduction process
CDO22_RS24350	COG0583	DNA-binding transcription factor activity
CDO22_RS24550	COG4372	Transposase
CDO22_RS24580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDO22_RS24585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDO22_RS24610	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS24615	COG3842	ATPase activity
CDO22_RS24630	COG1177	transmembrane transport
CDO22_RS24640	COG1063	alcohol dehydrogenase
CDO22_RS24670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO22_RS24675	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CDO22_RS24685	COG1744	ABC transporter substrate-binding protein PnrA-like
CDO22_RS24690	COG3845	ABC transporter
CDO22_RS24695	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS24700	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS24710	COG1957	nucleoside hydrolase
CDO22_RS24715	COG0402	S-adenosylhomocysteine deaminase activity
CDO22_RS24720	COG3609	addiction module antidote protein, CC2985 family
CDO22_RS24735	COG2814	Major facilitator Superfamily
CDO22_RS24745	COG0583	DNA-binding transcription factor activity
CDO22_RS24750	COG2186	Transcriptional regulator
CDO22_RS24760	COG1126	abc transporter atp-binding protein
CDO22_RS24770	COG0765	amino acid transport
CDO22_RS24775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO22_RS24790	COG0436	Aminotransferase
CDO22_RS24795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO22_RS24800	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS24815	COG1484	DNA-dependent DNA replication
CDO22_RS24820	COG4584	PFAM Integrase catalytic
CDO22_RS24835	COG0444	Belongs to the ABC transporter superfamily
CDO22_RS24840	COG4608	Belongs to the ABC transporter superfamily
CDO22_RS24845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS24850	COG0601	transmembrane transport
CDO22_RS24855	COG4166	transmembrane transport
CDO22_RS24860	COG1737	Transcriptional regulator
CDO22_RS24860	COG0837	glucose binding
CDO22_RS24870	COG2423	ornithine cyclodeaminase activity
CDO22_RS24880	COG3048	D-serine ammonia-lyase activity
CDO22_RS24945	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CDO22_RS25010	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS25075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS25090	COG0747	negative chemotaxis
CDO22_RS25095	COG0583	DNA-binding transcription factor activity
CDO22_RS25145	COG1126	abc transporter atp-binding protein
CDO22_RS25150	COG0765	amino acid transport
CDO22_RS25155	COG0765	amino acid transport
CDO22_RS25160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO22_RS25165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS25170	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS25175	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS25180	COG3938	Belongs to the proline racemase family
CDO22_RS25190	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS25210	COG4221	oxidoreductase activity
CDO22_RS25240	COG1802	Transcriptional regulator
CDO22_RS25245	COG1063	alcohol dehydrogenase
CDO22_RS25250	COG3321	synthase
CDO22_RS25250	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS25250	COG0604	alcohol dehydrogenase
CDO22_RS25280	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS25285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDO22_RS25290	COG0277	FAD linked oxidase domain protein
CDO22_RS25295	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CDO22_RS25305	COG2944	sequence-specific DNA binding
CDO22_RS25335	COG0251	oxidation-reduction process
CDO22_RS25355	COG1414	Transcriptional regulator
CDO22_RS25365	COG0477	Major facilitator Superfamily
CDO22_RS25370	COG0028	Belongs to the TPP enzyme family
CDO22_RS25375	COG2855	membrane
CDO22_RS25395	COG0583	DNA-binding transcription factor activity
CDO22_RS25400	COG4638	Rieske (2fe-2S)
CDO22_RS25415	COG2267	carboxylic ester hydrolase activity
CDO22_RS25425	COG2267	carboxylic ester hydrolase activity
CDO22_RS25430	COG1309	transcriptional regulator
CDO22_RS25445	COG1278	Cold shock
CDO22_RS25480	COG1335	isochorismatase
CDO22_RS25500	COG1846	Transcriptional regulator
CDO22_RS25545	COG1309	transcriptional regulator
CDO22_RS25555	COG1940	carbohydrate kinase activity
CDO22_RS25565	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS25570	COG1129	ABC transporter
CDO22_RS25575	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS25580	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS25595	COG3311	Transcriptional regulator
CDO22_RS25600	COG0583	DNA-binding transcription factor activity
CDO22_RS25615	COG0583	DNA-binding transcription factor activity
CDO22_RS25625	COG0235	Class ii aldolase
CDO22_RS25650	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS25660	COG0583	DNA-binding transcription factor activity
CDO22_RS25670	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CDO22_RS25685	COG2814	Major facilitator Superfamily
CDO22_RS25720	COG2963	transposase activity
CDO22_RS25725	COG3436	PFAM IS66 Orf2 family protein
CDO22_RS25730	COG4372	Transposase
CDO22_RS25770	COG0583	DNA-binding transcription factor activity
CDO22_RS25825	COG0640	Transcriptional regulator
CDO22_RS25885	COG0471	metal ion transport
CDO22_RS25885	COG3273	potassium ion transport
CDO22_RS25940	COG1404	Belongs to the peptidase S8 family
CDO22_RS25965	COG0583	DNA-binding transcription factor activity
CDO22_RS25970	COG0492	ferredoxin-NADP+ reductase activity
CDO22_RS25975	COG0492	ferredoxin-NADP+ reductase activity
CDO22_RS26005	COG1120	ATPase activity
CDO22_RS26015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO22_RS26025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO22_RS26040	COG1522	sequence-specific DNA binding
CDO22_RS26050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS26055	COG0601	transmembrane transport
CDO22_RS26075	COG0454	-acetyltransferase
CDO22_RS26085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS26095	COG0473	3-isopropylmalate dehydrogenase activity
CDO22_RS26100	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS26115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO22_RS26130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO22_RS26140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS26145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS26145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO22_RS26150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS26165	COG2358	TRAP transporter, solute receptor (TAXI family
CDO22_RS26175	COG1609	Transcriptional regulator
CDO22_RS26180	COG2233	PERMEase
CDO22_RS26185	COG0402	S-adenosylhomocysteine deaminase activity
CDO22_RS26215	COG1177	transmembrane transport
CDO22_RS26220	COG3842	ATPase activity
CDO22_RS26225	COG2072	flavoprotein involved in K transport
CDO22_RS26240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO22_RS26250	COG3246	L-lysine catabolic process to acetate
CDO22_RS26270	COG2814	Major facilitator Superfamily
CDO22_RS26275	COG1765	OsmC-like protein
CDO22_RS26280	COG3938	Belongs to the proline racemase family
CDO22_RS26290	COG3938	Belongs to the proline racemase family
CDO22_RS26295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS26305	COG0765	amino acid transport
CDO22_RS26325	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CDO22_RS26335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO22_RS26345	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO22_RS26385	COG1260	myo-inositol-1-phosphate synthase
CDO22_RS26395	COG0673	inositol 2-dehydrogenase activity
CDO22_RS26400	COG1063	alcohol dehydrogenase
CDO22_RS26410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS26435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS26455	COG3842	ATPase activity
CDO22_RS26465	COG0395	ABC-type sugar transport system, permease component
CDO22_RS26470	COG1175	transmembrane transport
CDO22_RS26475	COG2182	Extracellular solute-binding protein
CDO22_RS26480	COG1609	Transcriptional regulator
CDO22_RS26525	COG0596	Alpha beta hydrolase
CDO22_RS26530	COG0596	Alpha beta hydrolase
CDO22_RS26560	COG0300	oxidoreductase activity
CDO22_RS26575	COG0583	DNA-binding transcription factor activity
CDO22_RS26580	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS26590	COG0535	radical SAM domain protein
CDO22_RS26595	COG0535	radical SAM domain protein
CDO22_RS26600	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CDO22_RS26605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDO22_RS26615	COG0583	DNA-binding transcription factor activity
CDO22_RS26620	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CDO22_RS26625	COG3954	Phosphoribulokinase
CDO22_RS26630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO22_RS26635	COG0191	fructose-bisphosphate aldolase activity
CDO22_RS26640	COG1850	ribulose-bisphosphate carboxylase activity
CDO22_RS26645	COG4451	ribulose bisphosphate carboxylase, small
CDO22_RS26670	COG3791	Glutathione-dependent formaldehyde-activating
CDO22_RS26675	COG0842	Transport permease protein
CDO22_RS26680	COG1131	(ABC) transporter
CDO22_RS26685	COG1116	anion transmembrane transporter activity
CDO22_RS26745	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDO22_RS26750	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDO22_RS26825	COG3842	ATPase activity
CDO22_RS26830	COG1178	ABC-type Fe3 transport system permease component
CDO22_RS26835	COG1609	Transcriptional regulator
CDO22_RS26860	COG3395	kinase activity
CDO22_RS26870	COG1454	alcohol dehydrogenase
CDO22_RS26875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO22_RS26885	COG0747	negative chemotaxis
CDO22_RS26890	COG0601	transmembrane transport
CDO22_RS26895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS26905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO22_RS26925	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CDO22_RS26935	COG2233	PERMEase
CDO22_RS26940	COG0523	cobalamin synthesis protein
CDO22_RS26945	COG2080	2 iron, 2 sulfur cluster binding
CDO22_RS26945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS26955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO22_RS26975	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS26980	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS26985	COG3845	ABC transporter
CDO22_RS26990	COG0583	DNA-binding transcription factor activity
CDO22_RS27025	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS27040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO22_RS27045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO22_RS27060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS27065	COG0601	transmembrane transport
CDO22_RS27070	COG0747	negative chemotaxis
CDO22_RS27085	COG1802	Transcriptional regulator
CDO22_RS27100	COG3284	Transcriptional regulator
CDO22_RS27105	COG0579	oxidoreductase
CDO22_RS27110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO22_RS27140	COG0028	Belongs to the TPP enzyme family
CDO22_RS27150	COG0392	lysyltransferase activity
CDO22_RS27160	COG3685	Protein conserved in bacteria
CDO22_RS27235	COG2197	response regulator
CDO22_RS27240	COG4585	Histidine kinase
CDO22_RS27245	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS27260	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS27270	COG2814	Major facilitator Superfamily
CDO22_RS27280	COG0659	secondary active sulfate transmembrane transporter activity
CDO22_RS27285	COG1115	amino acid carrier protein
CDO22_RS27290	COG3360	Dodecin
CDO22_RS27315	COG3609	addiction module antidote protein, CC2985 family
CDO22_RS27340	COG1120	ATPase activity
CDO22_RS27345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO22_RS27365	COG2358	TRAP transporter, solute receptor (TAXI family
CDO22_RS27390	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDO22_RS27395	COG2188	Transcriptional regulator
CDO22_RS27405	COG1192	Involved in chromosome partitioning
CDO22_RS27410	COG1475	DNA binding
CDO22_RS27415	COG1414	Transcriptional regulator
CDO22_RS27435	COG0697	spore germination
CDO22_RS27440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO22_RS27455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDO22_RS27460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS27465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS27470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO22_RS27475	COG1309	transcriptional regulator
CDO22_RS27490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO22_RS27545	COG1522	sequence-specific DNA binding
CDO22_RS27550	COG0022	dehydrogenase e1 component
CDO22_RS27555	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO22_RS27570	COG1129	ABC transporter
CDO22_RS27575	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS27580	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS27585	COG1609	Transcriptional regulator
CDO22_RS27610	COG0583	DNA-binding transcription factor activity
CDO22_RS27615	COG1793	dna ligase
CDO22_RS27620	COG0753	catalase activity
CDO22_RS27630	COG0625	glutathione transferase activity
CDO22_RS27640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDO22_RS27690	COG1486	melibiose metabolic process
CDO22_RS27695	COG0747	negative chemotaxis
CDO22_RS27700	COG0601	transmembrane transport
CDO22_RS27705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS27710	COG4172	Belongs to the ABC transporter superfamily
CDO22_RS27715	COG1486	melibiose metabolic process
CDO22_RS27730	COG3396	Phenylacetate-CoA oxygenase
CDO22_RS27735	COG3460	Phenylacetate-CoA oxygenase
CDO22_RS27740	COG3396	Phenylacetate-CoA oxygenase
CDO22_RS27745	COG2151	metal-sulfur cluster biosynthetic enzyme
CDO22_RS27750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDO22_RS27755	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS27755	COG2030	dehydratase
CDO22_RS27760	COG1607	acyl-coa hydrolase
CDO22_RS27765	COG1024	Enoyl-CoA hydratase
CDO22_RS27770	COG1024	Enoyl-CoA hydratase
CDO22_RS27770	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO22_RS27775	COG0019	diaminopimelate decarboxylase activity
CDO22_RS27795	COG1175	transmembrane transport
CDO22_RS27800	COG0395	ABC-type sugar transport system, permease component
CDO22_RS27820	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDO22_RS27835	COG2814	Major facilitator Superfamily
CDO22_RS27845	COG2022	thiamine diphosphate biosynthetic process
CDO22_RS27860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDO22_RS27870	COG2204	response regulator
CDO22_RS27875	COG4191	Histidine kinase
CDO22_RS27880	COG1301	dicarboxylic acid transport
CDO22_RS27890	COG5002	protein histidine kinase activity
CDO22_RS27890	COG0784	Response regulator, receiver
CDO22_RS27890	COG2198	Histidine kinase
CDO22_RS27895	COG1672	PFAM Archaeal ATPase
CDO22_RS27895	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO22_RS27940	COG0411	ABC transporter
CDO22_RS27955	COG1475	DNA binding
CDO22_RS27960	COG1192	Involved in chromosome partitioning
CDO22_RS27990	COG1595	DNA-templated transcription, initiation
CDO22_RS27995	COG1254	Belongs to the acylphosphatase family
CDO22_RS28000	COG0183	Belongs to the thiolase family
CDO22_RS28005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDO22_RS28010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDO22_RS28015	COG1414	Transcriptional regulator
CDO22_RS28025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO22_RS28045	COG0583	DNA-binding transcription factor activity
CDO22_RS28050	COG2267	carboxylic ester hydrolase activity
CDO22_RS28055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO22_RS28060	COG3485	protocatechuate 3,4-dioxygenase
CDO22_RS28065	COG3485	protocatechuate 3,4-dioxygenase
CDO22_RS28085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO22_RS28090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO22_RS28095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO22_RS28105	COG0683	leucine binding
CDO22_RS28120	COG0411	ABC transporter
CDO22_RS28125	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO22_RS28145	COG1802	Transcriptional regulator
CDO22_RS28150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO22_RS28175	COG2376	Dihydroxyacetone kinase
CDO22_RS28185	COG4778	phosphonate C-P lyase system protein PhnL
CDO22_RS28190	COG4107	phosphonate C-P lyase system protein PhnK
CDO22_RS28195	COG3627	carbon phosphorus lyase activity
CDO22_RS28200	COG3626	phosphonate metabolism
CDO22_RS28205	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CDO22_RS28210	COG3624	Phosphonate C-P lyase system protein PhnG
CDO22_RS28215	COG2188	Transcriptional regulator
CDO22_RS28220	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDO22_RS28220	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDO22_RS28225	COG4770	biotin carboxylase activity
CDO22_RS28230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO22_RS28235	COG1396	sequence-specific DNA binding
CDO22_RS28235	COG3800	Transcriptional regulator
CDO22_RS28240	COG1960	acyl-CoA dehydrogenase activity
CDO22_RS28245	COG1024	Enoyl-CoA hydratase
CDO22_RS28255	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS28260	COG0246	Mannitol dehydrogenase
CDO22_RS28265	COG1215	transferase activity, transferring glycosyl groups
CDO22_RS28270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO22_RS28280	COG0174	glutamine synthetase
CDO22_RS28340	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS28345	COG1129	ABC transporter
CDO22_RS28350	COG1609	Transcriptional regulator
CDO22_RS28365	COG4211	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS28370	COG1129	ABC transporter
CDO22_RS28385	COG2084	Dehydrogenase
CDO22_RS28390	COG2094	Belongs to the DNA glycosylase MPG family
CDO22_RS28395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO22_RS28415	COG0297	glycogen (starch) synthase activity
CDO22_RS28450	COG4187	Peptidase family M20/M25/M40
CDO22_RS28470	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS28475	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS28505	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDO22_RS28515	COG3257	ureidoglycine aminohydrolase activity
CDO22_RS28520	COG0583	DNA-binding transcription factor activity
CDO22_RS28525	COG1414	Transcriptional regulator
CDO22_RS28530	COG3960	tartronate-semialdehyde synthase activity
CDO22_RS28535	COG3622	Belongs to the hyi family
CDO22_RS28540	COG2084	Dehydrogenase
CDO22_RS28550	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CDO22_RS28575	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS28580	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS28585	COG3395	kinase activity
CDO22_RS28590	COG3622	Belongs to the hyi family
CDO22_RS28595	COG2084	Dehydrogenase
CDO22_RS28600	COG1609	Transcriptional regulator
CDO22_RS28605	COG0235	Class ii aldolase
CDO22_RS28620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS28625	COG4221	oxidoreductase activity
CDO22_RS28630	COG3842	ATPase activity
CDO22_RS28640	COG1175	transmembrane transport
CDO22_RS28645	COG0395	ABC-type sugar transport system, permease component
CDO22_RS28655	COG0667	Aldo Keto reductase
CDO22_RS28675	COG0367	asparagine synthase
CDO22_RS28685	COG0318	PFAM AMP-dependent synthetase and ligase
CDO22_RS28690	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDO22_RS28700	COG0656	L-ascorbic acid biosynthetic process
CDO22_RS28710	COG0850	regulation of cytokinetic process
CDO22_RS28715	COG2894	cell division
CDO22_RS28720	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDO22_RS28730	COG2197	response regulator
CDO22_RS28735	COG4585	Histidine kinase
CDO22_RS28750	COG1388	LysM domain
CDO22_RS28750	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS28760	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO22_RS28780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO22_RS28800	COG0297	glycogen (starch) synthase activity
CDO22_RS28810	COG3609	addiction module antidote protein, CC2985 family
CDO22_RS28820	COG3415	Transposase
CDO22_RS28820	COG2801	Transposase and inactivated derivatives
CDO22_RS28825	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS28885	COG3346	SURF1 family
CDO22_RS28890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDO22_RS28895	COG1845	cytochrome c oxidase, subunit III
CDO22_RS28900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO22_RS28910	COG0477	Major facilitator Superfamily
CDO22_RS28950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CDO22_RS28990	COG0300	oxidoreductase activity
CDO22_RS29030	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CDO22_RS29035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO22_RS29040	COG2188	Transcriptional regulator
CDO22_RS29045	COG1486	melibiose metabolic process
CDO22_RS29050	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CDO22_RS29050	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDO22_RS29055	COG1653	transport
CDO22_RS29060	COG3842	ATPase activity
CDO22_RS29120	COG1573	uracil-dna glycosylase
CDO22_RS29125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDO22_RS29180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS29185	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO22_RS29190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS29200	COG0583	DNA-binding transcription factor activity
CDO22_RS29210	COG2226	methyltransferase
CDO22_RS29220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO22_RS29225	COG1120	ATPase activity
CDO22_RS29255	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS29260	COG1129	ABC transporter
CDO22_RS29295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDO22_RS29310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDO22_RS29315	COG3189	MarR family transcriptional regulator
CDO22_RS29340	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDO22_RS29350	COG1335	isochorismatase
CDO22_RS29430	COG3547	Transposase (IS116 IS110 IS902 family)
CDO22_RS29435	COG3547	Transposase (IS116 IS110 IS902 family)
CDO22_RS29450	COG1129	ABC transporter
CDO22_RS29455	COG4214	carbohydrate transport
CDO22_RS29460	COG4213	ABC transporter substrate-binding protein
CDO22_RS29480	COG0673	inositol 2-dehydrogenase activity
CDO22_RS29505	COG4213	ABC transporter substrate-binding protein
CDO22_RS29515	COG4214	carbohydrate transport
CDO22_RS29525	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS29530	COG0129	dihydroxy-acid dehydratase activity
CDO22_RS29540	COG1305	Transglutaminase-like
CDO22_RS29550	COG2308	Evidence 4 Homologs of previously reported genes of
CDO22_RS29575	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO22_RS29585	COG0513	Belongs to the DEAD box helicase family
CDO22_RS29595	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CDO22_RS29595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO22_RS29615	COG3648	Uricase
CDO22_RS29615	COG3195	allantoin biosynthetic process
CDO22_RS29620	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CDO22_RS29625	COG2351	hydroxyisourate hydrolase activity
CDO22_RS29630	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS29635	COG0583	DNA-binding transcription factor activity
CDO22_RS29640	COG4566	intracellular signal transduction
CDO22_RS29645	COG4566	intracellular signal transduction
CDO22_RS29650	COG4191	Histidine kinase
CDO22_RS29660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO22_RS29705	COG2140	Oxalate decarboxylase
CDO22_RS29710	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS29715	COG1129	ABC transporter
CDO22_RS29720	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS29725	COG1063	alcohol dehydrogenase
CDO22_RS29730	COG1069	ribulokinase activity
CDO22_RS29735	COG2390	Transcriptional regulator
CDO22_RS29745	COG0402	S-adenosylhomocysteine deaminase activity
CDO22_RS29755	COG0583	DNA-binding transcription factor activity
CDO22_RS29765	COG2801	Transposase and inactivated derivatives
CDO22_RS29765	COG3415	Transposase
CDO22_RS29770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS29785	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS29790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDO22_RS29825	COG0024	Methionine aminopeptidase
CDO22_RS29835	COG0477	Major facilitator Superfamily
CDO22_RS29840	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CDO22_RS29860	COG1160	GTP binding
CDO22_RS29865	COG1959	2 iron, 2 sulfur cluster binding
CDO22_RS29895	COG0330	HflC and HflK could
CDO22_RS29905	COG1051	belongs to the nudix hydrolase family
CDO22_RS29910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO22_RS29910	COG1648	precorrin-2 dehydrogenase activity
CDO22_RS29915	COG0243	molybdopterin cofactor binding
CDO22_RS29925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO22_RS29940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS29950	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS29970	COG0765	amino acid transport
CDO22_RS29980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO22_RS29985	COG3842	ATPase activity
CDO22_RS29995	COG1175	transmembrane transport
CDO22_RS30000	COG0395	ABC-type sugar transport system, permease component
CDO22_RS30010	COG1609	Transcriptional regulator
CDO22_RS30025	COG0450	alkyl hydroperoxide reductase
CDO22_RS30040	COG0351	phosphomethylpyrimidine kinase
CDO22_RS30050	COG3206	protein involved in exopolysaccharide biosynthesis
CDO22_RS30050	COG0489	protein tyrosine kinase activity
CDO22_RS30055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO22_RS30060	COG1215	transferase activity, transferring glycosyl groups
CDO22_RS30065	COG1215	transferase activity, transferring glycosyl groups
CDO22_RS30070	COG1215	transferase activity, transferring glycosyl groups
CDO22_RS30075	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS30080	COG2273	Hydrolase Family 16
CDO22_RS30085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO22_RS30100	COG1525	nuclease
CDO22_RS30110	COG2244	polysaccharide biosynthetic process
CDO22_RS30115	COG0463	Glycosyl transferase, family 2
CDO22_RS30120	COG2327	Polysaccharide pyruvyl transferase
CDO22_RS30125	COG1215	transferase activity, transferring glycosyl groups
CDO22_RS30135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDO22_RS30140	COG1596	polysaccharide export
CDO22_RS30145	COG3307	-O-antigen
CDO22_RS30150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO22_RS30155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDO22_RS30160	COG5265	(ABC) transporter
CDO22_RS30165	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDO22_RS30170	COG0720	synthase
CDO22_RS30175	COG0602	queuosine metabolic process
CDO22_RS30200	COG0784	Response regulator, receiver
CDO22_RS30205	COG3920	Histidine kinase
CDO22_RS30205	COG2202	Pas domain
CDO22_RS30210	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CDO22_RS30210	COG2273	Hydrolase Family 16
CDO22_RS30220	COG1129	ABC transporter
CDO22_RS30225	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS30230	COG3409	Peptidoglycan-binding domain 1 protein
CDO22_RS30230	COG0793	Belongs to the peptidase S41A family
CDO22_RS30240	COG0750	zinc metalloprotease
CDO22_RS30260	COG2182	Extracellular solute-binding protein
CDO22_RS30265	COG1175	transmembrane transport
CDO22_RS30270	COG0395	ABC-type sugar transport system, permease component
CDO22_RS30290	COG1609	Transcriptional regulator
CDO22_RS30295	COG0673	inositol 2-dehydrogenase activity
CDO22_RS30305	COG1653	transport
CDO22_RS30310	COG1175	transmembrane transport
CDO22_RS30325	COG2186	Transcriptional regulator
CDO22_RS30330	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS30335	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS30340	COG1129	ABC transporter
CDO22_RS30345	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS30350	COG0189	ligase activity
CDO22_RS30375	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS30380	COG1238	metal cluster binding
CDO22_RS30385	COG0789	Transcriptional regulator
CDO22_RS30390	COG2217	Heavy metal translocating P-type atpase
CDO22_RS30415	COG0640	Transcriptional regulator
CDO22_RS30425	COG2205	protein histidine kinase activity
CDO22_RS30445	COG1902	pentaerythritol trinitrate reductase activity
CDO22_RS30445	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO22_RS30455	COG5425	PFAM Usg family protein
CDO22_RS30460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO22_RS30465	COG0459	protein refolding
CDO22_RS30495	COG2205	protein histidine kinase activity
CDO22_RS30505	COG2080	2 iron, 2 sulfur cluster binding
CDO22_RS30510	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO22_RS30515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS30520	COG0475	glutathione-regulated potassium exporter activity
CDO22_RS30520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO22_RS30525	COG2801	Transposase and inactivated derivatives
CDO22_RS30550	COG2897	thiosulfate sulfurtransferase activity
CDO22_RS30565	COG3275	phosphorelay sensor kinase activity
CDO22_RS30590	COG3842	ATPase activity
CDO22_RS30595	COG1840	ABC-type Fe3 transport system, periplasmic component
CDO22_RS30605	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS30615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO22_RS30635	COG1349	DNA-binding transcription factor activity
CDO22_RS30645	COG2855	membrane
CDO22_RS30650	COG0028	Belongs to the TPP enzyme family
CDO22_RS30665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO22_RS30670	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CDO22_RS30675	COG4521	taurine ABC transporter
CDO22_RS30680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO22_RS30685	COG2207	Transcriptional regulator
CDO22_RS30690	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CDO22_RS30695	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS30710	COG3485	protocatechuate 3,4-dioxygenase
CDO22_RS30725	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS30730	COG1129	ABC transporter
CDO22_RS30735	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS30740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO22_RS30745	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CDO22_RS30750	COG1609	Transcriptional regulator
CDO22_RS30760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO22_RS30770	COG2010	Cytochrome c
CDO22_RS30770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO22_RS30800	COG1295	ribonuclease BN
CDO22_RS30810	COG2323	membrane
CDO22_RS30845	COG0673	inositol 2-dehydrogenase activity
CDO22_RS30850	COG1904	glucuronate isomerase
CDO22_RS30855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS30870	COG2186	Transcriptional regulator
CDO22_RS30875	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CDO22_RS30880	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS30890	COG1609	Transcriptional regulator
CDO22_RS30895	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS30900	COG1129	ABC transporter
CDO22_RS30905	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS30910	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS30920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS30925	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO22_RS30930	COG2080	2 iron, 2 sulfur cluster binding
CDO22_RS30940	COG0628	permease
CDO22_RS30965	COG3237	CsbD-like
CDO22_RS30980	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDO22_RS30990	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CDO22_RS31030	COG1846	Transcriptional regulator
CDO22_RS31040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO22_RS31060	COG0297	glycogen (starch) synthase activity
CDO22_RS31090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO22_RS31095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDO22_RS31110	COG2194	sulfuric ester hydrolase activity
CDO22_RS31115	COG0745	RESPONSE REGULATOR receiver
CDO22_RS31120	COG2205	protein histidine kinase activity
CDO22_RS31130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO22_RS31135	COG1131	(ABC) transporter
CDO22_RS31140	COG0842	Transport permease protein
CDO22_RS31145	COG0842	Transport permease protein
CDO22_RS31160	COG0346	lactoylglutathione lyase activity
CDO22_RS31175	COG4172	Belongs to the ABC transporter superfamily
CDO22_RS31180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS31185	COG0601	transmembrane transport
CDO22_RS31190	COG4166	transmembrane transport
CDO22_RS31200	COG1132	(ABC) transporter
CDO22_RS31210	COG1216	Glycosyl transferase, family 2
CDO22_RS31215	COG2755	lipolytic protein G-D-S-L family
CDO22_RS31215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO22_RS31225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO22_RS31230	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS31235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDO22_RS31240	COG0326	Molecular chaperone. Has ATPase activity
CDO22_RS31245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDO22_RS31250	COG1960	acyl-CoA dehydrogenase activity
CDO22_RS31270	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CDO22_RS31280	COG3639	organic phosphonate transmembrane transporter activity
CDO22_RS31285	COG3639	organic phosphonate transmembrane transporter activity
CDO22_RS31295	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CDO22_RS31300	COG3454	Phosphonate metabolism
CDO22_RS31305	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CDO22_RS31310	COG0640	Transcriptional regulator
CDO22_RS31315	COG2814	Major facilitator Superfamily
CDO22_RS31325	COG1228	amidohydrolase
CDO22_RS31330	COG2986	histidine ammonia-lyase
CDO22_RS31340	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CDO22_RS31365	COG1737	Transcriptional regulator
CDO22_RS31370	COG0251	oxidation-reduction process
CDO22_RS31395	COG3842	ATPase activity
CDO22_RS31405	COG0395	ABC-type sugar transport system, permease component
CDO22_RS31415	COG0673	inositol 2-dehydrogenase activity
CDO22_RS31420	COG1174	glycine betaine transport
CDO22_RS31425	COG1125	glycine betaine transport
CDO22_RS31430	COG1174	glycine betaine transport
CDO22_RS31435	COG1732	Glycine betaine
CDO22_RS31440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO22_RS31465	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS31470	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDO22_RS31475	COG1349	DNA-binding transcription factor activity
CDO22_RS31485	COG4953	penicillin-binding protein 1C
CDO22_RS31495	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO22_RS31500	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO22_RS31505	COG0402	S-adenosylhomocysteine deaminase activity
CDO22_RS31525	COG1733	regulation of RNA biosynthetic process
CDO22_RS31535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS31545	COG2351	hydroxyisourate hydrolase activity
CDO22_RS31550	COG3648	Uricase
CDO22_RS31550	COG3195	allantoin biosynthetic process
CDO22_RS31555	COG4266	Belongs to the allantoicase family
CDO22_RS31565	COG2252	PERMEase
CDO22_RS31570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDO22_RS31575	COG1473	amidohydrolase
CDO22_RS31580	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO22_RS31590	COG3842	ATPase activity
CDO22_RS31595	COG1177	transmembrane transport
CDO22_RS31600	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO22_RS31610	COG1609	Transcriptional regulator
CDO22_RS31620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO22_RS31620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO22_RS31625	COG1132	(ABC) transporter
CDO22_RS31650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS31655	COG0601	transmembrane transport
CDO22_RS31660	COG0747	negative chemotaxis
CDO22_RS31705	COG0668	transmembrane transport
CDO22_RS31710	COG0438	transferase activity, transferring glycosyl groups
CDO22_RS31720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDO22_RS31730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDO22_RS31735	COG1596	polysaccharide export
CDO22_RS31750	COG0297	glycogen (starch) synthase activity
CDO22_RS31780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO22_RS31810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO22_RS31815	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO22_RS31830	COG0529	Catalyzes the synthesis of activated sulfate
CDO22_RS31830	COG2895	sulfate adenylyltransferase (ATP) activity
CDO22_RS31835	COG0175	sulfate reduction
CDO22_RS31840	COG1940	carbohydrate kinase activity
CDO22_RS31840	COG1846	Transcriptional regulator
CDO22_RS31870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO22_RS31875	COG3842	ATPase activity
CDO22_RS31885	COG0251	oxidation-reduction process
CDO22_RS31895	COG0765	amino acid transport
CDO22_RS31900	COG0765	amino acid transport
CDO22_RS31915	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDO22_RS31925	COG4208	sulfate ABC transporter
CDO22_RS31930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO22_RS31935	COG0277	FAD linked oxidase domain protein
CDO22_RS31975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO22_RS31980	COG1960	acyl-CoA dehydrogenase activity
CDO22_RS31990	COG3265	gluconokinase activity
CDO22_RS32000	COG1396	sequence-specific DNA binding
CDO22_RS32010	COG3707	response regulator
CDO22_RS32015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO22_RS32020	COG4948	Mandelate Racemase Muconate Lactonizing
CDO22_RS32025	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO22_RS32030	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS32045	COG3254	rhamnose metabolic process
CDO22_RS32050	COG4948	Mandelate Racemase Muconate Lactonizing
CDO22_RS32055	COG3842	ATPase activity
CDO22_RS32060	COG0395	ABC-type sugar transport system, permease component
CDO22_RS32075	COG1414	Transcriptional regulator
CDO22_RS32095	COG2079	MmgE PrpD family protein
CDO22_RS32115	COG0165	Argininosuccinate lyase
CDO22_RS32125	COG0456	acetyltransferase
CDO22_RS32140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDO22_RS32165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO22_RS32185	COG3328	transposase activity
CDO22_RS32210	COG1525	nuclease
CDO22_RS32215	COG1396	sequence-specific DNA binding
CDO22_RS32245	COG3285	dna ligase
CDO22_RS32245	COG1793	dna ligase
CDO22_RS32255	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDO22_RS32260	COG2843	Capsule synthesis protein
CDO22_RS32270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS32275	COG0601	transmembrane transport
CDO22_RS32380	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS32395	COG3347	Dehydrogenase
CDO22_RS32395	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS32410	COG1696	Membrane protein involved in D-alanine export
CDO22_RS32455	COG0463	Glycosyl transferase, family 2
CDO22_RS32485	COG1083	cytidylyl-transferase
CDO22_RS32490	COG2089	acid synthase
CDO22_RS32520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO22_RS32540	COG1609	Transcriptional regulator
CDO22_RS32555	COG1132	(ABC) transporter
CDO22_RS32575	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDO22_RS32575	COG0517	IMP dehydrogenase activity
CDO22_RS32585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO22_RS32650	COG2832	Protein of unknown function (DUF454)
CDO22_RS32775	COG1609	Transcriptional regulator
CDO22_RS32825	COG2201	protein-glutamate methylesterase activity
CDO22_RS32840	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS32845	COG4948	Mandelate Racemase Muconate Lactonizing
CDO22_RS32850	COG2186	Transcriptional regulator
CDO22_RS32860	COG1129	ABC transporter
CDO22_RS32880	COG1129	ABC transporter
CDO22_RS32885	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS32895	COG0667	Aldo Keto reductase
CDO22_RS32900	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CDO22_RS32910	COG1070	Carbohydrate kinase
CDO22_RS32930	COG0583	DNA-binding transcription factor activity
CDO22_RS32935	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS32955	COG0235	Class ii aldolase
CDO22_RS32975	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS32980	COG1129	ABC transporter
CDO22_RS33000	COG0367	asparagine synthase
CDO22_RS33005	COG2188	Transcriptional regulator
CDO22_RS33010	COG4608	Belongs to the ABC transporter superfamily
CDO22_RS33020	COG0601	transmembrane transport
CDO22_RS33025	COG0747	negative chemotaxis
CDO22_RS33050	COG2192	nodulation
CDO22_RS33080	COG4585	Histidine kinase
CDO22_RS33085	COG1363	Peptidase, m42
CDO22_RS33135	COG1028	Short-chain dehydrogenase reductase Sdr
CDO22_RS33140	COG1309	transcriptional regulator
CDO22_RS33180	COG3300	MHYT domain
CDO22_RS33180	COG5001	Diguanylate cyclase
CDO22_RS33185	COG1312	Catalyzes the dehydration of D-mannonate
CDO22_RS33190	COG1063	alcohol dehydrogenase
CDO22_RS33195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS33205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS33220	COG3608	succinylglutamate desuccinylase aspartoacylase
CDO22_RS33225	COG0006	proline dipeptidase activity
CDO22_RS33230	COG2423	ornithine cyclodeaminase activity
CDO22_RS33235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO22_RS33240	COG3473	Maleate cis-trans isomerase
CDO22_RS33245	COG0765	amino acid transport
CDO22_RS33250	COG0765	amino acid transport
CDO22_RS33260	COG1126	abc transporter atp-binding protein
CDO22_RS33265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO22_RS33270	COG1522	sequence-specific DNA binding
CDO22_RS33275	COG1012	belongs to the aldehyde dehydrogenase family
CDO22_RS33280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO22_RS33285	COG1063	alcohol dehydrogenase
CDO22_RS33295	COG0625	glutathione transferase activity
CDO22_RS33300	COG3842	ATPase activity
CDO22_RS33305	COG0395	ABC-type sugar transport system, permease component
CDO22_RS33310	COG1175	transmembrane transport
CDO22_RS33315	COG1653	transport
CDO22_RS33355	COG4647	ligase activity
CDO22_RS33360	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CDO22_RS33365	COG0145	ligase activity
CDO22_RS33375	COG2010	Cytochrome c
CDO22_RS33375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS33380	COG2080	2 iron, 2 sulfur cluster binding
CDO22_RS33385	COG2010	Cytochrome c
CDO22_RS33385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS33410	COG2080	2 iron, 2 sulfur cluster binding
CDO22_RS33415	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO22_RS33420	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS33430	COG1850	ribulose-bisphosphate carboxylase activity
CDO22_RS33435	COG2186	Transcriptional regulator
CDO22_RS33460	COG0604	alcohol dehydrogenase
CDO22_RS33490	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO22_RS33495	COG1177	transmembrane transport
CDO22_RS33500	COG3842	ATPase activity
CDO22_RS33505	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO22_RS33525	COG2186	Transcriptional regulator
CDO22_RS33530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS33540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS33545	COG0698	ribose 5-phosphate isomerase
CDO22_RS33560	COG1609	Transcriptional regulator
CDO22_RS33565	COG1840	ABC-type Fe3 transport system, periplasmic component
CDO22_RS33575	COG3842	ATPase activity
CDO22_RS33610	COG0784	Response regulator, receiver
CDO22_RS33610	COG2205	protein histidine kinase activity
CDO22_RS33625	COG0673	inositol 2-dehydrogenase activity
CDO22_RS33630	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS33635	COG1129	ABC transporter
CDO22_RS33655	COG0287	Prephenate dehydrogenase
CDO22_RS33675	COG2207	Transcriptional regulator
CDO22_RS33685	COG2010	Cytochrome c
CDO22_RS33685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO22_RS33715	COG1309	transcriptional regulator
CDO22_RS33735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO22_RS33760	COG4566	intracellular signal transduction
CDO22_RS33765	COG4566	intracellular signal transduction
CDO22_RS33770	COG4191	Histidine kinase
CDO22_RS33780	COG2985	domain, Protein
CDO22_RS33790	COG2985	domain, Protein
CDO22_RS33795	COG0714	Associated with various cellular activities
CDO22_RS33830	COG3119	arylsulfatase activity
CDO22_RS33840	COG0673	inositol 2-dehydrogenase activity
CDO22_RS33850	COG3842	ATPase activity
CDO22_RS33865	COG1653	transport
CDO22_RS33870	COG1609	Transcriptional regulator
CDO22_RS33890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO22_RS33905	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS33910	COG1129	ABC transporter
CDO22_RS33915	COG1879	ABC-type sugar transport system periplasmic component
CDO22_RS33925	COG2376	Dihydroxyacetone kinase
CDO22_RS33930	COG1461	Dihydroxyacetone kinase
CDO22_RS33935	COG2376	Dihydroxyacetone kinase
CDO22_RS33955	COG2133	pyrroloquinoline quinone binding
CDO22_RS33980	COG0785	Cytochrome C biogenesis protein
CDO22_RS33985	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDO22_RS33985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDO22_RS34005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO22_RS34010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO22_RS34035	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO22_RS34085	COG0789	Transcriptional regulator
CDO22_RS34090	COG1309	transcriptional regulator
CDO22_RS34130	COG1238	metal cluster binding
CDO22_RS34340	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS34350	COG3547	Transposase (IS116 IS110 IS902 family)
CDO22_RS34395	COG4227	nucleotidyltransferase activity
CDO22_RS34400	COG1192	Involved in chromosome partitioning
CDO22_RS34405	COG1475	DNA binding
CDO22_RS34410	COG0640	Transcriptional regulator
CDO22_RS34455	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
CDO22_RS34530	COG1074	ATP-dependent DNA helicase activity
CDO22_RS34535	COG1401	restriction endodeoxyribonuclease activity
CDO22_RS34565	COG1802	Transcriptional regulator
CDO22_RS34570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO22_RS34585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO22_RS34590	COG0154	amidase activity
CDO22_RS34605	COG0601	transmembrane transport
CDO22_RS34610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS34615	COG4172	Belongs to the ABC transporter superfamily
CDO22_RS34620	COG0747	negative chemotaxis
CDO22_RS34635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO22_RS34640	COG0601	transmembrane transport
CDO22_RS34645	COG0747	negative chemotaxis
CDO22_RS34650	COG0402	S-adenosylhomocysteine deaminase activity
CDO22_RS34660	COG0402	S-adenosylhomocysteine deaminase activity
CDO22_RS34665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDO22_RS34680	COG3300	MHYT domain
CDO22_RS34680	COG5001	Diguanylate cyclase
CDO22_RS34685	COG2267	carboxylic ester hydrolase activity
CDO22_RS34710	COG1129	ABC transporter
CDO22_RS34715	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO22_RS34720	COG1737	Transcriptional regulator
CDO22_RS34730	COG2902	Dehydrogenase
CDO22_RS34740	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO22_RS34740	COG1672	PFAM Archaeal ATPase
CDO22_RS34755	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CDO22_RS34790	COG3920	Histidine kinase
CDO22_RS34795	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CDO22_RS34800	COG4957	zinc ion binding
CDO22_RS34820	COG3831	ATPase activity
CDO22_RS34870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDO22_RS34880	COG0431	NADPH-dependent FMN reductase
CDO22_RS34905	COG0601	transmembrane transport
CDO22_RS34930	COG1388	LysM domain
CDO22_RS34930	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS34940	COG3034	peptidoglycan biosynthetic process
CDO22_RS34960	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS34965	COG1321	iron dependent repressor
CDO22_RS34985	COG2124	cytochrome p450
CDO22_RS34995	COG1376	ErfK ybiS ycfS ynhG family protein
CDO22_RS35000	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDO22_RS35000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDO22_RS35005	COG1999	signal sequence binding
CDO22_RS35015	COG2132	Multicopper oxidase