locus-tag	class	description
CDO23_RS00005	COG3459	Glycosyltransferase 36 associated
CDO23_RS00020	COG1132	(ABC) transporter
CDO23_RS00030	COG3328	transposase activity
CDO23_RS00040	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDO23_RS00045	COG1126	abc transporter atp-binding protein
CDO23_RS00050	COG0765	amino acid transport
CDO23_RS00055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO23_RS00065	COG2223	nitrite transmembrane transporter activity
CDO23_RS00070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDO23_RS00085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO23_RS00090	COG0142	geranyltranstransferase activity
CDO23_RS00095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDO23_RS00100	COG0625	glutathione transferase activity
CDO23_RS00105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDO23_RS00110	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CDO23_RS00115	COG0183	Belongs to the thiolase family
CDO23_RS00120	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS00135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDO23_RS00140	COG1329	Transcriptional regulator
CDO23_RS00145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO23_RS00155	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CDO23_RS00180	COG0488	(ABC) transporter
CDO23_RS00185	COG0765	amino acid transport
CDO23_RS00195	COG0335	large ribosomal subunit rRNA binding
CDO23_RS00205	COG0336	Belongs to the RNA methyltransferase TrmD family
CDO23_RS00210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDO23_RS00215	COG0228	four-way junction DNA binding
CDO23_RS00220	COG1605	Chorismate mutase
CDO23_RS00220	COG0287	Prephenate dehydrogenase
CDO23_RS00225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDO23_RS00235	COG2161	toxin-antitoxin pair type II binding
CDO23_RS00240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDO23_RS00245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDO23_RS00250	COG0552	protein localization to endoplasmic reticulum
CDO23_RS00255	COG2917	probably involved in intracellular septation
CDO23_RS00275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO23_RS00280	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO23_RS00285	COG4133	protoheme IX ABC transporter activity
CDO23_RS00290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDO23_RS00305	COG0640	Transcriptional regulator
CDO23_RS00315	COG0740	serine-type endopeptidase activity
CDO23_RS00325	COG0670	Belongs to the BI1 family
CDO23_RS00335	COG4181	ATPase activity
CDO23_RS00345	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CDO23_RS00350	COG2154	pterin-4-alpha-carbinolamine dehydratase
CDO23_RS00365	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDO23_RS00375	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS00390	COG0137	argininosuccinate synthase activity
CDO23_RS00395	COG0477	Major facilitator Superfamily
CDO23_RS00410	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDO23_RS00425	COG0745	RESPONSE REGULATOR receiver
CDO23_RS00440	COG1940	carbohydrate kinase activity
CDO23_RS00450	COG1129	ABC transporter
CDO23_RS00455	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS00460	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS00480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDO23_RS00485	COG1674	ftsk spoiiie
CDO23_RS00490	COG0004	ammonium transporteR
CDO23_RS00495	COG0347	Belongs to the P(II) protein family
CDO23_RS00500	COG1946	Acyl-CoA thioesterase
CDO23_RS00505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO23_RS00515	COG2835	tetraacyldisaccharide 4'-kinase activity
CDO23_RS00520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO23_RS00525	COG3118	belongs to the thioredoxin family
CDO23_RS00550	COG1129	ABC transporter
CDO23_RS00555	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS00560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDO23_RS00565	COG0022	dehydrogenase e1 component
CDO23_RS00575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO23_RS00580	COG1070	Carbohydrate kinase
CDO23_RS00590	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS00605	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDO23_RS00610	COG0251	oxidation-reduction process
CDO23_RS00615	COG0066	3-isopropylmalate dehydratase activity
CDO23_RS00645	COG0587	DNA-directed DNA polymerase activity
CDO23_RS00660	COG0494	nUDIX hydrolase
CDO23_RS00665	COG2861	carbohydrate metabolic process
CDO23_RS00670	COG0793	Belongs to the peptidase S41A family
CDO23_RS00680	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDO23_RS00685	COG0799	negative regulation of ribosome biogenesis
CDO23_RS00690	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDO23_RS00695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDO23_RS00700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDO23_RS00705	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDO23_RS00720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDO23_RS00725	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDO23_RS00750	COG0154	amidase activity
CDO23_RS00755	COG4249	Peptidase C14 caspase catalytic subunit p20
CDO23_RS00765	COG1217	gtp-binding protein TYPA
CDO23_RS00780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDO23_RS00795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDO23_RS00795	COG0519	Catalyzes the synthesis of GMP from XMP
CDO23_RS00820	COG0181	hydroxymethylbilane synthase activity
CDO23_RS00825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDO23_RS00830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDO23_RS00850	COG3385	transposase activity
CDO23_RS00860	COG2009	succinate dehydrogenase
CDO23_RS00880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO23_RS00905	COG1175	transmembrane transport
CDO23_RS00910	COG0395	ABC-type sugar transport system, permease component
CDO23_RS00920	COG2845	Protein of unknown function (DUF459)
CDO23_RS00925	COG3549	Plasmid maintenance system killer
CDO23_RS00935	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDO23_RS00940	COG0039	L-malate dehydrogenase activity
CDO23_RS00945	COG0045	succinate-CoA ligase (ADP-forming) activity
CDO23_RS00950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDO23_RS00955	COG0567	Dehydrogenase, E1 component
CDO23_RS00960	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO23_RS00975	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS00985	COG3328	transposase activity
CDO23_RS00995	COG4974	Belongs to the 'phage' integrase family
CDO23_RS01005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDO23_RS01025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDO23_RS01040	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDO23_RS01045	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDO23_RS01050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDO23_RS01055	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDO23_RS01060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDO23_RS01080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO23_RS01085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO23_RS01090	COG1121	(ABC) transporter
CDO23_RS01095	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDO23_RS01110	COG2233	PERMEase
CDO23_RS01115	COG2233	PERMEase
CDO23_RS01130	COG0395	ABC-type sugar transport system, permease component
CDO23_RS01140	COG3842	ATPase activity
CDO23_RS01145	COG3842	ATPase activity
CDO23_RS01165	COG0583	DNA-binding transcription factor activity
CDO23_RS01185	COG3383	formate dehydrogenase (NAD+) activity
CDO23_RS01190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDO23_RS01205	COG0835	chemotaxis
CDO23_RS01210	COG0010	Belongs to the arginase family
CDO23_RS01245	COG2267	carboxylic ester hydrolase activity
CDO23_RS01275	COG0156	8-amino-7-oxononanoate synthase activity
CDO23_RS01280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDO23_RS01305	COG1940	carbohydrate kinase activity
CDO23_RS01310	COG4702	Belongs to the UPF0303 family
CDO23_RS01315	COG2942	2-epimerase
CDO23_RS01325	COG3328	transposase activity
CDO23_RS01340	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS01400	COG2390	Transcriptional regulator
CDO23_RS01405	COG0747	negative chemotaxis
CDO23_RS01425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS01430	COG0584	glycerophosphoryl diester phosphodiesterase
CDO23_RS01440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO23_RS01445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS01450	COG0765	amino acid transport
CDO23_RS01460	COG1126	abc transporter atp-binding protein
CDO23_RS01475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO23_RS01485	COG1802	Transcriptional regulator
CDO23_RS01495	COG5001	Diguanylate cyclase
CDO23_RS01495	COG3300	MHYT domain
CDO23_RS01520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO23_RS01540	COG2197	response regulator
CDO23_RS01560	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CDO23_RS01570	COG0625	glutathione transferase activity
CDO23_RS01590	COG0022	dehydrogenase e1 component
CDO23_RS01605	COG3585	molybdate ion transport
CDO23_RS01605	COG2005	Transcriptional regulator
CDO23_RS01610	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CDO23_RS01615	COG4149	molybdate abc transporter
CDO23_RS01625	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDO23_RS01630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO23_RS01675	COG0583	DNA-binding transcription factor activity
CDO23_RS01685	COG1320	monovalent cation:proton antiporter activity
CDO23_RS01690	COG2212	antiporter activity
CDO23_RS01695	COG1863	multisubunit Na H antiporter MnhE subunit
CDO23_RS01700	COG0651	ATP synthesis coupled electron transport
CDO23_RS01705	COG1006	Multisubunit Na H antiporter MnhC subunit
CDO23_RS01710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO23_RS01710	COG2111	Na H antiporter
CDO23_RS01720	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO23_RS01720	COG1793	dna ligase
CDO23_RS01740	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDO23_RS01745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDO23_RS01750	COG1253	flavin adenine dinucleotide binding
CDO23_RS01755	COG2207	Transcriptional regulator
CDO23_RS01755	COG3708	Transcriptional regulator
CDO23_RS01760	COG1309	transcriptional regulator
CDO23_RS01780	COG1609	Transcriptional regulator
CDO23_RS01785	COG1070	Carbohydrate kinase
CDO23_RS01790	COG2115	Belongs to the xylose isomerase family
CDO23_RS01800	COG0673	inositol 2-dehydrogenase activity
CDO23_RS01810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDO23_RS01815	COG2011	ABC-type metal ion transport system permease component
CDO23_RS01820	COG1464	Belongs to the NlpA lipoprotein family
CDO23_RS01825	COG1054	Belongs to the UPF0176 family
CDO23_RS01835	COG2954	triphosphatase activity
CDO23_RS01840	COG0800	Aldolase
CDO23_RS01875	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CDO23_RS01885	COG0583	DNA-binding transcription factor activity
CDO23_RS01900	COG1280	lysine exporter protein (LysE YggA)
CDO23_RS01915	COG0523	cobalamin synthesis protein
CDO23_RS01925	COG1846	Transcriptional regulator
CDO23_RS01930	COG1609	Transcriptional regulator
CDO23_RS01935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO23_RS01940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDO23_RS01945	COG5001	Diguanylate cyclase
CDO23_RS01990	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDO23_RS02000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS02010	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO23_RS02010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO23_RS02035	COG1523	belongs to the glycosyl hydrolase 13 family
CDO23_RS02040	COG0033	Phosphoglucomutase
CDO23_RS02045	COG0297	glycogen (starch) synthase activity
CDO23_RS02050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDO23_RS02055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDO23_RS02060	COG0058	SHG alpha-glucan phosphorylase activity
CDO23_RS02070	COG1305	Transglutaminase-like
CDO23_RS02080	COG0667	Aldo Keto reductase
CDO23_RS02085	COG0583	DNA-binding transcription factor activity
CDO23_RS02140	COG0129	dihydroxy-acid dehydratase activity
CDO23_RS02170	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO23_RS02175	COG0747	negative chemotaxis
CDO23_RS02185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS02190	COG0601	transmembrane transport
CDO23_RS02195	COG2267	carboxylic ester hydrolase activity
CDO23_RS02200	COG2197	response regulator
CDO23_RS02225	COG0067	glutamate synthase
CDO23_RS02225	COG0070	glutamate synthase
CDO23_RS02225	COG0069	glutamate synthase activity
CDO23_RS02240	COG2951	lytic endotransglycosylase activity
CDO23_RS02245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO23_RS02255	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDO23_RS02260	COG0330	HflC and HflK could
CDO23_RS02265	COG1070	Carbohydrate kinase
CDO23_RS02270	COG2390	Transcriptional regulator
CDO23_RS02275	COG0371	Dehydrogenase
CDO23_RS02290	COG1175	transmembrane transport
CDO23_RS02295	COG0395	ABC-type sugar transport system, permease component
CDO23_RS02305	COG4221	oxidoreductase activity
CDO23_RS02310	COG3842	ATPase activity
CDO23_RS02315	COG3347	Dehydrogenase
CDO23_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS02325	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDO23_RS02330	COG0737	Belongs to the 5'-nucleotidase family
CDO23_RS02340	COG5310	Homospermidine synthase
CDO23_RS02355	COG0512	Glutamine amidotransferase of anthranilate synthase
CDO23_RS02355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO23_RS02365	COG2204	response regulator
CDO23_RS02370	COG3108	Peptidase M15
CDO23_RS02375	COG3750	Belongs to the UPF0335 family
CDO23_RS02395	COG0469	pyruvate kinase activity
CDO23_RS02400	COG0457	Tetratricopeptide repeat
CDO23_RS02405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDO23_RS02410	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDO23_RS02415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDO23_RS02430	COG0640	Transcriptional regulator
CDO23_RS02450	COG0483	inositol monophosphate 1-phosphatase activity
CDO23_RS02465	COG1132	(ABC) transporter
CDO23_RS02470	COG0254	rRNA binding
CDO23_RS02500	COG0384	phenazine biosynthesis protein PhzF
CDO23_RS02505	COG3588	fructose-bisphosphate aldolase
CDO23_RS02510	COG0126	phosphoglycerate kinase activity
CDO23_RS02560	COG1692	metallophosphoesterase
CDO23_RS02565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO23_RS02580	COG0217	transcriptional regulatory protein
CDO23_RS02585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO23_RS02590	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDO23_RS02595	COG0632	four-way junction helicase activity
CDO23_RS02600	COG2255	four-way junction helicase activity
CDO23_RS02605	COG1408	metallophosphoesterase
CDO23_RS02625	COG0824	Thioesterase
CDO23_RS02650	COG0823	Involved in the tonB-independent uptake of proteins
CDO23_RS02655	COG2885	chlorophyll binding
CDO23_RS02665	COG0037	tRNA processing
CDO23_RS02670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDO23_RS02675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDO23_RS02695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO23_RS02700	COG3547	Transposase (IS116 IS110 IS902 family)
CDO23_RS02710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDO23_RS02720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO23_RS02725	COG0564	pseudouridine synthase activity
CDO23_RS02740	COG3547	Transposase (IS116 IS110 IS902 family)
CDO23_RS02785	COG2771	luxR family
CDO23_RS02790	COG0482	sulfurtransferase activity
CDO23_RS02875	COG3314	Sporulation integral membrane protein YlbJ
CDO23_RS02880	COG2986	histidine ammonia-lyase
CDO23_RS02885	COG4175	Glycine betaine
CDO23_RS02885	COG0517	IMP dehydrogenase activity
CDO23_RS02890	COG4176	ABC-type proline glycine betaine transport system permease component
CDO23_RS02910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO23_RS02915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO23_RS02920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO23_RS02925	COG1522	sequence-specific DNA binding
CDO23_RS02930	COG2207	Transcriptional regulator
CDO23_RS02935	COG1064	alcohol dehydrogenase
CDO23_RS02945	COG1473	amidohydrolase
CDO23_RS02950	COG1686	Belongs to the peptidase S11 family
CDO23_RS02955	COG0523	cobalamin synthesis protein
CDO23_RS02975	COG3034	peptidoglycan biosynthetic process
CDO23_RS02980	COG0825	malonyl-CoA metabolic process
CDO23_RS02985	COG4974	Belongs to the 'phage' integrase family
CDO23_RS02995	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDO23_RS03000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDO23_RS03005	COG4536	flavin adenine dinucleotide binding
CDO23_RS03035	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CDO23_RS03040	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDO23_RS03060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO23_RS03065	COG2226	methyltransferase
CDO23_RS03070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO23_RS03075	COG0287	Prephenate dehydrogenase
CDO23_RS03085	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CDO23_RS03105	COG2884	Cell division ATP-binding protein ftsE
CDO23_RS03115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO23_RS03150	COG0165	Argininosuccinate lyase
CDO23_RS03155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO23_RS03160	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO23_RS03165	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDO23_RS03170	COG2086	electron transfer activity
CDO23_RS03180	COG2096	Adenosyltransferase
CDO23_RS03190	COG0300	oxidoreductase activity
CDO23_RS03200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDO23_RS03235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO23_RS03255	COG0653	protein targeting
CDO23_RS03260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO23_RS03265	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDO23_RS03275	COG0494	nUDIX hydrolase
CDO23_RS03290	COG2226	methyltransferase
CDO23_RS03305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO23_RS03315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDO23_RS03325	COG0527	aspartate kinase activity
CDO23_RS03330	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CDO23_RS03335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDO23_RS03340	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO23_RS03355	COG0542	response to heat
CDO23_RS03360	COG0739	heme binding
CDO23_RS03400	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO23_RS03405	COG0583	DNA-binding transcription factor activity
CDO23_RS03410	COG0723	plastoquinol--plastocyanin reductase activity
CDO23_RS03425	COG1802	Transcriptional regulator
CDO23_RS03435	COG4608	Belongs to the ABC transporter superfamily
CDO23_RS03440	COG0444	Belongs to the ABC transporter superfamily
CDO23_RS03445	COG1228	amidohydrolase
CDO23_RS03455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS03460	COG0601	transmembrane transport
CDO23_RS03480	COG0402	S-adenosylhomocysteine deaminase activity
CDO23_RS03490	COG1335	isochorismatase
CDO23_RS03515	COG0683	leucine binding
CDO23_RS03520	COG1335	isochorismatase
CDO23_RS03535	COG0174	glutamine synthetase
CDO23_RS03540	COG4774	siderophore transport
CDO23_RS03580	COG0477	Major facilitator Superfamily
CDO23_RS03585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO23_RS03590	COG1070	Carbohydrate kinase
CDO23_RS03595	COG2188	Transcriptional regulator
CDO23_RS03600	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS03605	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS03610	COG1129	ABC transporter
CDO23_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS03635	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDO23_RS03640	COG1737	Transcriptional regulator
CDO23_RS03645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDO23_RS03650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO23_RS03660	COG0800	Aldolase
CDO23_RS03665	COG2140	Oxalate decarboxylase
CDO23_RS03670	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS03685	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS03690	COG1802	Transcriptional regulator
CDO23_RS03705	COG1175	transmembrane transport
CDO23_RS03710	COG0395	ABC-type sugar transport system, permease component
CDO23_RS03720	COG3842	ATPase activity
CDO23_RS03725	COG3842	ATPase activity
CDO23_RS03745	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS03750	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS03760	COG1129	ABC transporter
CDO23_RS03765	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS03770	COG0583	DNA-binding transcription factor activity
CDO23_RS03775	COG0601	transmembrane transport
CDO23_RS03800	COG1473	amidohydrolase
CDO23_RS03825	COG1129	ABC transporter
CDO23_RS03830	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS03855	COG1063	alcohol dehydrogenase
CDO23_RS03890	COG1845	cytochrome c oxidase, subunit III
CDO23_RS03895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO23_RS03900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO23_RS03910	COG3842	ATPase activity
CDO23_RS03915	COG0395	ABC-type sugar transport system, permease component
CDO23_RS03930	COG0626	cystathionine gamma-synthase activity
CDO23_RS03935	COG1725	Transcriptional regulator
CDO23_RS03945	COG0174	glutamine synthetase
CDO23_RS03950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS03970	COG0436	Aminotransferase
CDO23_RS03990	COG3842	ATPase activity
CDO23_RS03995	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO23_RS04005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO23_RS04010	COG0346	lactoylglutathione lyase activity
CDO23_RS04040	COG0400	carboxylic ester hydrolase activity
CDO23_RS04050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO23_RS04055	COG0784	Response regulator, receiver
CDO23_RS04095	COG1846	Transcriptional regulator
CDO23_RS04105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO23_RS04110	COG0829	nickel cation binding
CDO23_RS04115	COG0831	urea catabolic process
CDO23_RS04120	COG3813	Protein conserved in bacteria
CDO23_RS04125	COG0832	Belongs to the urease beta subunit family
CDO23_RS04130	COG3755	Protein conserved in bacteria
CDO23_RS04135	COG1442	glycosyl transferase family 8
CDO23_RS04140	COG0804	urea catabolic process
CDO23_RS04170	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CDO23_RS04175	COG0830	nickel cation binding
CDO23_RS04180	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CDO23_RS04200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO23_RS04205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO23_RS04210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO23_RS04240	COG1309	transcriptional regulator
CDO23_RS04255	COG0583	DNA-binding transcription factor activity
CDO23_RS04260	COG1063	alcohol dehydrogenase
CDO23_RS04270	COG0493	'glutamate synthase
CDO23_RS04285	COG1175	transmembrane transport
CDO23_RS04290	COG0395	ABC-type sugar transport system, permease component
CDO23_RS04320	COG0784	Response regulator, receiver
CDO23_RS04335	COG2202	Pas domain
CDO23_RS04335	COG3920	Histidine kinase
CDO23_RS04350	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CDO23_RS04355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO23_RS04360	COG4558	Periplasmic binding protein
CDO23_RS04410	COG2346	COG2346, Truncated hemoglobins
CDO23_RS04430	COG2076	Multidrug Resistance protein
CDO23_RS04445	COG0601	transmembrane transport
CDO23_RS04450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS04455	COG0444	Belongs to the ABC transporter superfamily
CDO23_RS04460	COG4608	Belongs to the ABC transporter superfamily
CDO23_RS04465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO23_RS04470	COG0366	Alpha amylase catalytic
CDO23_RS04475	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO23_RS04480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO23_RS04515	COG1435	thymidine kinase activity
CDO23_RS04540	COG2852	Protein conserved in bacteria
CDO23_RS04560	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDO23_RS04575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO23_RS04575	COG0512	Glutamine amidotransferase of anthranilate synthase
CDO23_RS04580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDO23_RS04585	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDO23_RS04605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDO23_RS04615	COG0740	serine-type endopeptidase activity
CDO23_RS04625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDO23_RS04630	COG4423	Transcription factor
CDO23_RS04635	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
CDO23_RS04645	COG1595	DNA-templated transcription, initiation
CDO23_RS04670	COG0435	Glutathione S-transferase
CDO23_RS04695	COG0714	Associated with various cellular activities
CDO23_RS04720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDO23_RS04740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDO23_RS04745	COG0193	aminoacyl-tRNA hydrolase activity
CDO23_RS04750	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDO23_RS04755	COG3135	benzoate transporter
CDO23_RS04765	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS04775	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CDO23_RS04780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDO23_RS04795	COG1496	oxidoreductase activity
CDO23_RS04805	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDO23_RS04825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO23_RS04830	COG2205	protein histidine kinase activity
CDO23_RS04835	COG0745	RESPONSE REGULATOR receiver
CDO23_RS04840	COG1846	Transcriptional regulator
CDO23_RS04860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO23_RS04870	COG1278	Cold shock
CDO23_RS04880	COG2133	pyrroloquinoline quinone binding
CDO23_RS04895	COG0436	Aminotransferase
CDO23_RS04900	COG2084	Dehydrogenase
CDO23_RS04905	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS04915	COG0505	Belongs to the CarA family
CDO23_RS04925	COG0358	DNA primase activity
CDO23_RS04930	COG0514	ATP-dependent DNA helicase (RecQ)
CDO23_RS04940	COG1063	alcohol dehydrogenase
CDO23_RS04945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO23_RS04965	COG5507	3-demethylubiquinone-9 3-methyltransferase
CDO23_RS04970	COG0432	Pfam Uncharacterised protein family UPF0047
CDO23_RS04985	COG2968	Membrane
CDO23_RS05020	COG1696	Membrane protein involved in D-alanine export
CDO23_RS05140	COG1024	Enoyl-CoA hydratase
CDO23_RS05200	COG4774	siderophore transport
CDO23_RS05205	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS05210	COG1177	transmembrane transport
CDO23_RS05215	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO23_RS05220	COG3842	ATPase activity
CDO23_RS05230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CDO23_RS05235	COG0583	DNA-binding transcription factor activity
CDO23_RS05245	COG3547	Transposase (IS116 IS110 IS902 family)
CDO23_RS05270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS05280	COG0747	negative chemotaxis
CDO23_RS05300	COG1960	acyl-CoA dehydrogenase activity
CDO23_RS05305	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO23_RS05305	COG0824	Thioesterase
CDO23_RS05310	COG3246	L-lysine catabolic process to acetate
CDO23_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS05325	COG1177	transmembrane transport
CDO23_RS05340	COG3842	ATPase activity
CDO23_RS05345	COG2197	response regulator
CDO23_RS05355	COG1653	transport
CDO23_RS05360	COG1175	transmembrane transport
CDO23_RS05370	COG3842	ATPase activity
CDO23_RS05390	COG0235	Class ii aldolase
CDO23_RS05405	COG1070	Carbohydrate kinase
CDO23_RS05420	COG1349	DNA-binding transcription factor activity
CDO23_RS05425	COG0149	triose-phosphate isomerase activity
CDO23_RS05435	COG4774	siderophore transport
CDO23_RS05445	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDO23_RS05450	COG3842	ATPase activity
CDO23_RS05485	COG0174	glutamine synthetase
CDO23_RS05490	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS05505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS05510	COG1376	ErfK ybiS ycfS ynhG family protein
CDO23_RS05525	COG0028	Belongs to the TPP enzyme family
CDO23_RS05535	COG2267	carboxylic ester hydrolase activity
CDO23_RS05540	COG3719	Belongs to the RNase T2 family
CDO23_RS05600	COG1280	lysine exporter protein (LysE YggA)
CDO23_RS05610	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CDO23_RS05615	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDO23_RS05635	COG2001	Belongs to the MraZ family
CDO23_RS05640	COG0275	rRNA processing
CDO23_RS05655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDO23_RS05665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDO23_RS05670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDO23_RS05680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDO23_RS05685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDO23_RS05690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDO23_RS05695	COG0477	Major facilitator Superfamily
CDO23_RS05700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDO23_RS05705	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO23_RS05710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDO23_RS05715	COG0849	cell division
CDO23_RS05720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDO23_RS05730	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO23_RS05740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDO23_RS05750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDO23_RS05755	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO23_RS05775	COG0006	proline dipeptidase activity
CDO23_RS05795	COG2264	protein methyltransferase activity
CDO23_RS05800	COG1999	signal sequence binding
CDO23_RS05810	COG0840	transmembrane signaling receptor activity
CDO23_RS05815	COG0835	chemotaxis
CDO23_RS05835	COG3706	GGDEF domain
CDO23_RS05870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO23_RS05885	COG0277	FAD linked oxidase domain protein
CDO23_RS05940	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDO23_RS05960	COG0330	HflC and HflK could
CDO23_RS05975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO23_RS05980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO23_RS05985	COG0560	Phosphoserine phosphatase
CDO23_RS05985	COG3830	Belongs to the UPF0237 family
CDO23_RS05990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDO23_RS06010	COG0028	Belongs to the TPP enzyme family
CDO23_RS06015	COG0440	acetolactate synthase activity
CDO23_RS06020	COG0656	L-ascorbic acid biosynthetic process
CDO23_RS06025	COG1278	Cold shock
CDO23_RS06065	COG1595	DNA-templated transcription, initiation
CDO23_RS06085	COG3180	Ammonia monooxygenase
CDO23_RS06090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDO23_RS06095	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO23_RS06100	COG1672	PFAM Archaeal ATPase
CDO23_RS06100	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS06145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDO23_RS06150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO23_RS06165	COG1733	regulation of RNA biosynthetic process
CDO23_RS06170	COG1794	racemase activity, acting on amino acids and derivatives
CDO23_RS06175	COG1522	sequence-specific DNA binding
CDO23_RS06180	COG1252	NADH dehydrogenase
CDO23_RS06190	COG2271	Major facilitator Superfamily
CDO23_RS06220	COG0577	efflux transmembrane transporter activity
CDO23_RS06220	COG1136	(ABC) transporter
CDO23_RS06225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO23_RS06235	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDO23_RS06255	COG1376	ErfK ybiS ycfS ynhG family protein
CDO23_RS06265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO23_RS06270	COG0667	Aldo Keto reductase
CDO23_RS06280	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDO23_RS06290	COG1278	Cold shock
CDO23_RS06305	COG4149	molybdate abc transporter
CDO23_RS06310	COG3842	ATPase activity
CDO23_RS06325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDO23_RS06340	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CDO23_RS06380	COG0384	phenazine biosynthesis protein PhzF
CDO23_RS06500	COG3750	Belongs to the UPF0335 family
CDO23_RS06535	COG2155	Conserved Protein
CDO23_RS06730	COG3179	chitinase
CDO23_RS06805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO23_RS06810	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CDO23_RS06830	COG1595	DNA-templated transcription, initiation
CDO23_RS06980	COG0463	Glycosyl transferase, family 2
CDO23_RS07020	COG3273	potassium ion transport
CDO23_RS07020	COG0471	metal ion transport
CDO23_RS07035	COG1196	nuclear chromosome segregation
CDO23_RS07035	COG3264	Mechanosensitive ion channel
CDO23_RS07040	COG0861	Integral membrane protein TerC family
CDO23_RS07065	COG0745	RESPONSE REGULATOR receiver
CDO23_RS07115	COG0583	DNA-binding transcription factor activity
CDO23_RS07120	COG0640	Transcriptional regulator
CDO23_RS07145	COG0646	methionine synthase
CDO23_RS07145	COG1410	methionine synthase
CDO23_RS07180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO23_RS07195	COG5012	cobalamin binding
CDO23_RS07200	COG5598	trimethylamine methyltransferase
CDO23_RS07210	COG3698	Phosphodiester glycosidase
CDO23_RS07230	COG1410	methionine synthase
CDO23_RS07230	COG0646	methionine synthase
CDO23_RS07235	COG0583	DNA-binding transcription factor activity
CDO23_RS07245	COG3609	addiction module antidote protein, CC2985 family
CDO23_RS07250	COG4175	Glycine betaine
CDO23_RS07250	COG0517	IMP dehydrogenase activity
CDO23_RS07265	COG1492	cobalamin metabolic process
CDO23_RS07270	COG0596	Alpha beta hydrolase
CDO23_RS07315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS07335	COG4172	Belongs to the ABC transporter superfamily
CDO23_RS07355	COG1797	cobyrinic acid a,c-diamide synthase activity
CDO23_RS07365	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDO23_RS07370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO23_RS07375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO23_RS07385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO23_RS07395	COG1560	Kdo2-lipid A biosynthetic process
CDO23_RS07420	COG1115	amino acid carrier protein
CDO23_RS07425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDO23_RS07445	COG1175	transmembrane transport
CDO23_RS07450	COG0395	ABC-type sugar transport system, permease component
CDO23_RS07455	COG3842	ATPase activity
CDO23_RS07460	COG3250	beta-galactosidase activity
CDO23_RS07475	COG0667	Aldo Keto reductase
CDO23_RS07480	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CDO23_RS07490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS07500	COG3507	Belongs to the glycosyl hydrolase 43 family
CDO23_RS07520	COG1121	(ABC) transporter
CDO23_RS07525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO23_RS07530	COG0735	belongs to the Fur family
CDO23_RS07540	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO23_RS07560	COG1138	Cytochrome C-type biogenesis protein
CDO23_RS07570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDO23_RS07590	COG0484	heat shock protein binding
CDO23_RS07600	COG0556	nucleotide-excision repair
CDO23_RS07645	COG0640	Transcriptional regulator
CDO23_RS07650	COG1131	(ABC) transporter
CDO23_RS07655	COG0842	Transport permease protein
CDO23_RS07670	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CDO23_RS07675	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDO23_RS07680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDO23_RS07695	COG1573	uracil-dna glycosylase
CDO23_RS07700	COG1522	sequence-specific DNA binding
CDO23_RS07710	COG2084	Dehydrogenase
CDO23_RS07725	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS07730	COG5425	PFAM Usg family protein
CDO23_RS07755	COG1763	Mo-molybdopterin cofactor biosynthetic process
CDO23_RS07760	COG0746	molybdenum cofactor guanylyltransferase activity
CDO23_RS07765	COG0697	spore germination
CDO23_RS07775	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDO23_RS07785	COG1846	Transcriptional regulator
CDO23_RS07790	COG2267	carboxylic ester hydrolase activity
CDO23_RS07800	COG0114	fumarate hydratase activity
CDO23_RS07805	COG2989	Protein conserved in bacteria
CDO23_RS07810	COG0546	phosphoglycolate phosphatase activity
CDO23_RS07815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDO23_RS07830	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CDO23_RS07860	COG1368	sulfuric ester hydrolase activity
CDO23_RS07870	COG0823	Involved in the tonB-independent uptake of proteins
CDO23_RS07890	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS07895	COG0778	Nitroreductase
CDO23_RS07910	COG2197	response regulator
CDO23_RS07915	COG0281	malic enzyme
CDO23_RS07915	COG0280	phosphate acetyltransferase
CDO23_RS07930	COG2814	Major facilitator Superfamily
CDO23_RS07935	COG4948	Mandelate Racemase Muconate Lactonizing
CDO23_RS07940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDO23_RS07945	COG1127	ABC transporter
CDO23_RS07955	COG3218	ABC-type transport auxiliary lipoprotein component
CDO23_RS07955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDO23_RS07960	COG3657	addiction module killer protein
CDO23_RS07975	COG0408	coproporphyrinogen oxidase activity
CDO23_RS07990	COG0789	Transcriptional regulator
CDO23_RS07995	COG0431	NADPH-dependent FMN reductase
CDO23_RS08000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDO23_RS08005	COG1132	(ABC) transporter
CDO23_RS08010	COG1132	(ABC) transporter
CDO23_RS08025	COG2857	Cytochrome c1
CDO23_RS08025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CDO23_RS08050	COG0633	Ferredoxin
CDO23_RS08065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDO23_RS08070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDO23_RS08085	COG3768	UPF0283 membrane protein
CDO23_RS08090	COG3106	COG3106 Predicted ATPase
CDO23_RS08115	COG2313	pseudouridylate synthase activity
CDO23_RS08120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO23_RS08125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDO23_RS08130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDO23_RS08135	COG0659	secondary active sulfate transmembrane transporter activity
CDO23_RS08140	COG0538	isocitrate dehydrogenase activity
CDO23_RS08150	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CDO23_RS08155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDO23_RS08165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDO23_RS08170	COG2066	Belongs to the glutaminase family
CDO23_RS08175	COG0037	tRNA processing
CDO23_RS08180	COG0483	inositol monophosphate 1-phosphatase activity
CDO23_RS08185	COG2814	Major facilitator Superfamily
CDO23_RS08190	COG2814	Major facilitator Superfamily
CDO23_RS08210	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO23_RS08225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO23_RS08240	COG0047	phosphoribosylformylglycinamidine synthase activity
CDO23_RS08245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO23_RS08250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDO23_RS08275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDO23_RS08295	COG3191	aminopeptidase activity
CDO23_RS08305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDO23_RS08310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO23_RS08325	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDO23_RS08325	COG3608	succinylglutamate desuccinylase aspartoacylase
CDO23_RS08330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDO23_RS08345	COG0513	Belongs to the DEAD box helicase family
CDO23_RS08350	COG0739	heme binding
CDO23_RS08355	COG2833	Protein of unknown function (DUF455)
CDO23_RS08360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDO23_RS08370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDO23_RS08375	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDO23_RS08380	COG3706	GGDEF domain
CDO23_RS08390	COG2945	thiolester hydrolase activity
CDO23_RS08400	COG0719	Fe-S assembly protein
CDO23_RS08405	COG0396	ATPase activity
CDO23_RS08410	COG0719	Fe-S assembly protein
CDO23_RS08415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDO23_RS08420	COG2151	metal-sulfur cluster biosynthetic enzyme
CDO23_RS08425	COG0316	Belongs to the HesB IscA family
CDO23_RS08435	COG2003	Belongs to the UPF0758 family
CDO23_RS08440	COG0024	Methionine aminopeptidase
CDO23_RS08445	COG1489	DNA binding
CDO23_RS08450	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDO23_RS08460	COG0436	Aminotransferase
CDO23_RS08505	COG1278	Cold shock
CDO23_RS08535	COG0583	DNA-binding transcription factor activity
CDO23_RS08575	COG1522	sequence-specific DNA binding
CDO23_RS08600	COG0583	DNA-binding transcription factor activity
CDO23_RS08605	COG2084	Dehydrogenase
CDO23_RS08610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS08615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS08620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS08625	COG3959	Transketolase, thiamine diphosphate binding domain
CDO23_RS08630	COG3958	Transketolase
CDO23_RS08635	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS08650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS08665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO23_RS08675	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS08765	COG0785	Cytochrome C biogenesis protein
CDO23_RS08770	COG0679	Auxin Efflux Carrier
CDO23_RS08775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO23_RS08785	COG1183	phosphatidylcholine synthase activity
CDO23_RS08795	COG3845	ABC transporter
CDO23_RS08800	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS08805	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS08815	COG2186	Transcriptional regulator
CDO23_RS08820	COG1253	flavin adenine dinucleotide binding
CDO23_RS08830	COG0303	'Molybdopterin
CDO23_RS08835	COG0315	cyclic pyranopterin monophosphate synthase activity
CDO23_RS08840	COG0134	indole-3-glycerol-phosphate synthase activity
CDO23_RS08845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDO23_RS08850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO23_RS08860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDO23_RS08865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO23_RS08870	COG3153	acetyltransferase
CDO23_RS08880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDO23_RS08885	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDO23_RS08890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDO23_RS08955	COG0174	glutamine synthetase
CDO23_RS08960	COG0347	Belongs to the P(II) protein family
CDO23_RS08965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDO23_RS08965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDO23_RS08970	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CDO23_RS08975	COG1546	Belongs to the CinA family
CDO23_RS08975	COG1058	Belongs to the CinA family
CDO23_RS08980	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDO23_RS09005	COG3795	YCII-related domain
CDO23_RS09020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDO23_RS09025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO23_RS09035	COG0737	Belongs to the 5'-nucleotidase family
CDO23_RS09040	COG1522	sequence-specific DNA binding
CDO23_RS09045	COG0686	Belongs to the AlaDH PNT family
CDO23_RS09060	COG2897	thiosulfate sulfurtransferase activity
CDO23_RS09075	COG4221	oxidoreductase activity
CDO23_RS09095	COG2076	Multidrug Resistance protein
CDO23_RS09185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDO23_RS09225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDO23_RS09235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO23_RS09240	COG0084	hydrolase, TatD family'
CDO23_RS09250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDO23_RS09280	COG1388	LysM domain
CDO23_RS09280	COG1376	ErfK ybiS ycfS ynhG family protein
CDO23_RS09305	COG0300	oxidoreductase activity
CDO23_RS09315	COG0343	queuine tRNA-ribosyltransferase activity
CDO23_RS09320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDO23_RS09335	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDO23_RS09345	COG5265	(ABC) transporter
CDO23_RS09350	COG0534	Mate efflux family protein
CDO23_RS09360	COG2321	neutral zinc metallopeptidase
CDO23_RS09370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDO23_RS09385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO23_RS09390	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS09395	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS09400	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS09405	COG0463	Glycosyl transferase, family 2
CDO23_RS09410	COG1522	sequence-specific DNA binding
CDO23_RS09415	COG0492	ferredoxin-NADP+ reductase activity
CDO23_RS09420	COG0583	DNA-binding transcription factor activity
CDO23_RS09430	COG1902	pentaerythritol trinitrate reductase activity
CDO23_RS09460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDO23_RS09465	COG2095	MarC family integral membrane protein
CDO23_RS09470	COG0629	single-stranded DNA binding
CDO23_RS09475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDO23_RS09485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDO23_RS09520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO23_RS09525	COG0509	glycine decarboxylation via glycine cleavage system
CDO23_RS09530	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDO23_RS09530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDO23_RS09535	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDO23_RS09555	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CDO23_RS09580	COG1862	Preprotein translocase
CDO23_RS09605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO23_RS09610	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CDO23_RS09615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDO23_RS09620	COG0805	protein transport
CDO23_RS09625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO23_RS09630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO23_RS09635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO23_RS09640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDO23_RS09645	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDO23_RS09650	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO23_RS09660	COG0018	arginyl-trna synthetase
CDO23_RS09665	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CDO23_RS09675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO23_RS09685	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CDO23_RS09695	COG0525	valine-tRNA ligase activity
CDO23_RS09710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO23_RS09720	COG0848	biopolymer transport protein
CDO23_RS09735	COG0372	Belongs to the citrate synthase family
CDO23_RS09750	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO23_RS09760	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO23_RS09765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO23_RS09770	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO23_RS09780	COG0750	zinc metalloprotease
CDO23_RS09790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDO23_RS09795	COG0233	cytoplasmic translational termination
CDO23_RS09800	COG0528	UMP kinase activity
CDO23_RS09805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDO23_RS09810	COG0052	Belongs to the universal ribosomal protein uS2 family
CDO23_RS09840	COG0537	adenosine 5'-monophosphoramidase activity
CDO23_RS09860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDO23_RS09875	COG1045	serine acetyltransferase
CDO23_RS09880	COG0596	Alpha beta hydrolase
CDO23_RS09895	COG0626	cystathionine gamma-synthase activity
CDO23_RS09900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO23_RS09905	COG4597	amino acid ABC transporter
CDO23_RS09910	COG0765	amino acid transport
CDO23_RS09915	COG1126	abc transporter atp-binding protein
CDO23_RS09935	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO23_RS09945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO23_RS09945	COG1648	precorrin-2 dehydrogenase activity
CDO23_RS09955	COG3956	TIGRFAM MazG family protein
CDO23_RS09980	COG3547	Transposase (IS116 IS110 IS902 family)
CDO23_RS09985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDO23_RS09990	COG1923	regulation of RNA biosynthetic process
CDO23_RS09995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO23_RS10000	COG0569	domain protein
CDO23_RS10005	COG2204	response regulator
CDO23_RS10010	COG5000	phosphorelay sensor kinase activity
CDO23_RS10015	COG2204	response regulator
CDO23_RS10020	COG3852	Histidine kinase
CDO23_RS10030	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDO23_RS10030	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDO23_RS10035	COG1058	Belongs to the CinA family
CDO23_RS10035	COG1546	Belongs to the CinA family
CDO23_RS10040	COG2867	negative regulation of translational initiation
CDO23_RS10045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDO23_RS10055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO23_RS10070	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO23_RS10075	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO23_RS10075	COG0022	dehydrogenase e1 component
CDO23_RS10080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDO23_RS10090	COG0148	phosphopyruvate hydratase activity
CDO23_RS10095	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CDO23_RS10105	COG0504	CTP synthase activity
CDO23_RS10110	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDO23_RS10115	COG0149	triose-phosphate isomerase activity
CDO23_RS10140	COG0187	DNA topoisomerase II activity
CDO23_RS10180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDO23_RS10195	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDO23_RS10205	COG0302	gtp cyclohydrolase
CDO23_RS10210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDO23_RS10220	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO23_RS10230	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CDO23_RS10275	COG1760	l-serine dehydratase
CDO23_RS10300	COG2239	Acts as a magnesium transporter
CDO23_RS10305	COG0242	peptide deformylase activity
CDO23_RS10325	COG2719	SpoVR family
CDO23_RS10330	COG2718	Belongs to the UPF0229 family
CDO23_RS10335	COG2766	serine protein kinase
CDO23_RS10345	COG0321	lipoyl(octanoyl) transferase activity
CDO23_RS10355	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDO23_RS10360	COG1671	Belongs to the UPF0178 family
CDO23_RS10370	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDO23_RS10375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDO23_RS10380	COG0564	pseudouridine synthase activity
CDO23_RS10385	COG0546	phosphoglycolate phosphatase activity
CDO23_RS10400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDO23_RS10405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO23_RS10415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO23_RS10420	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CDO23_RS10430	COG0203	ribosomal protein L17
CDO23_RS10435	COG0202	RNA polymerase activity
CDO23_RS10440	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDO23_RS10445	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDO23_RS10450	COG0563	adenylate kinase activity
CDO23_RS10460	COG0200	Binds to the 23S rRNA
CDO23_RS10465	COG1841	ribosomal large subunit assembly
CDO23_RS10470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDO23_RS10475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDO23_RS10480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDO23_RS10485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDO23_RS10490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDO23_RS10495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDO23_RS10500	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDO23_RS10505	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDO23_RS10510	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDO23_RS10515	COG0255	Belongs to the universal ribosomal protein uL29 family
CDO23_RS10520	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDO23_RS10525	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDO23_RS10530	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDO23_RS10535	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDO23_RS10540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDO23_RS10545	COG0089	rRNA binding
CDO23_RS10550	COG0088	Forms part of the polypeptide exit tunnel
CDO23_RS10555	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDO23_RS10560	COG0051	transcription antitermination factor activity, RNA binding
CDO23_RS10565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDO23_RS10570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDO23_RS10575	COG0049	tRNA binding
CDO23_RS10580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDO23_RS10590	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDO23_RS10595	COG0085	RNA polymerase activity
CDO23_RS10600	COG0222	ribosome binding
CDO23_RS10605	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDO23_RS10610	COG0081	regulation of translation
CDO23_RS10615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDO23_RS10640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS10650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDO23_RS10665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO23_RS10675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDO23_RS10690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDO23_RS10710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO23_RS10715	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO23_RS10725	COG1530	ribonuclease E activity
CDO23_RS10740	COG0436	Aminotransferase
CDO23_RS10755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDO23_RS10760	COG0511	ligase activity, forming carbon-carbon bonds
CDO23_RS10765	COG0439	Biotin carboxylase
CDO23_RS10770	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDO23_RS10790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDO23_RS10795	COG3811	Belongs to the UPF0386 family
CDO23_RS10800	COG0154	amidase activity
CDO23_RS10805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDO23_RS10810	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDO23_RS10815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDO23_RS10835	COG1960	acyl-CoA dehydrogenase activity
CDO23_RS10840	COG0540	Belongs to the ATCase OTCase family
CDO23_RS10845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDO23_RS10850	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDO23_RS10855	COG0758	DNA mediated transformation
CDO23_RS10860	COG1754	DNA topoisomerase type I activity
CDO23_RS10860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDO23_RS10865	COG0557	exoribonuclease II activity
CDO23_RS10885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDO23_RS10895	COG0784	Response regulator, receiver
CDO23_RS10905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO23_RS10915	COG3547	Transposase (IS116 IS110 IS902 family)
CDO23_RS10925	COG1136	(ABC) transporter
CDO23_RS10935	COG0442	prolyl-tRNA aminoacylation
CDO23_RS10945	COG3328	transposase activity
CDO23_RS10960	COG0346	lactoylglutathione lyase activity
CDO23_RS10975	COG1007	ATP synthesis coupled electron transport
CDO23_RS10990	COG0713	ATP synthesis coupled electron transport
CDO23_RS11000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO23_RS11005	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CDO23_RS11015	COG3743	rRNA binding
CDO23_RS11015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDO23_RS11020	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDO23_RS11025	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CDO23_RS11035	COG0649	NAD binding
CDO23_RS11040	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO23_RS11045	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO23_RS11050	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO23_RS11075	COG4717	serine-type aminopeptidase activity
CDO23_RS11080	COG0420	3'-5' exonuclease activity
CDO23_RS11100	COG0776	regulation of translation
CDO23_RS11105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO23_RS11110	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDO23_RS11115	COG0740	serine-type endopeptidase activity
CDO23_RS11120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO23_RS11130	COG2124	cytochrome p450
CDO23_RS11150	COG1832	CoA-binding protein
CDO23_RS11160	COG1024	Enoyl-CoA hydratase
CDO23_RS11170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDO23_RS11175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDO23_RS11180	COG0010	Belongs to the arginase family
CDO23_RS11185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDO23_RS11190	COG1612	heme a metabolic process
CDO23_RS11205	COG0110	maltose O-acetyltransferase activity
CDO23_RS11225	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS11240	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS11260	COG0776	regulation of translation
CDO23_RS11265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO23_RS11270	COG0416	fatty acid biosynthetic process
CDO23_RS11290	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CDO23_RS11295	COG2814	Major facilitator Superfamily
CDO23_RS11300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO23_RS11305	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDO23_RS11315	COG0519	Catalyzes the synthesis of GMP from XMP
CDO23_RS11330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO23_RS11330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO23_RS11335	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDO23_RS11340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDO23_RS11345	COG2989	Protein conserved in bacteria
CDO23_RS11360	COG0113	porphobilinogen synthase activity
CDO23_RS11370	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CDO23_RS11385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDO23_RS11400	COG0459	protein refolding
CDO23_RS11405	COG3385	transposase activity
CDO23_RS11415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDO23_RS11430	COG2132	Multicopper oxidase
CDO23_RS11435	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CDO23_RS11440	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS11450	COG0248	Ppx GppA phosphatase
CDO23_RS11455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CDO23_RS11465	COG0628	permease
CDO23_RS11470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDO23_RS11475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDO23_RS11490	COG0494	nUDIX hydrolase
CDO23_RS11495	COG0243	molybdopterin cofactor binding
CDO23_RS11500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDO23_RS11520	COG3547	Transposase (IS116 IS110 IS902 family)
CDO23_RS11530	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS11535	COG0322	excinuclease ABC activity
CDO23_RS11550	COG0314	molybdopterin synthase activity
CDO23_RS11575	COG0105	UTP biosynthetic process
CDO23_RS11590	COG0318	PFAM AMP-dependent synthetase and ligase
CDO23_RS11600	COG0488	(ABC) transporter
CDO23_RS11620	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO23_RS11650	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO23_RS11655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDO23_RS11665	COG0194	GDP metabolic process
CDO23_RS11670	COG1561	YicC-like family, N-terminal region
CDO23_RS11675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDO23_RS11680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO23_RS11685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO23_RS11695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDO23_RS11700	COG0667	Aldo Keto reductase
CDO23_RS11710	COG0360	Binds together with S18 to 16S ribosomal RNA
CDO23_RS11715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDO23_RS11725	COG0359	binds to the 23S rRNA
CDO23_RS11745	COG0305	Participates in initiation and elongation during chromosome replication
CDO23_RS11765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDO23_RS11780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDO23_RS11785	COG4221	oxidoreductase activity
CDO23_RS11790	COG1183	phosphatidylcholine synthase activity
CDO23_RS11795	COG0688	phosphatidylethanolamine metabolic process
CDO23_RS11800	COG5265	(ABC) transporter
CDO23_RS11815	COG2962	Rard protein
CDO23_RS11820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDO23_RS11845	COG0215	cysteine-tRNA ligase activity
CDO23_RS11865	COG1051	belongs to the nudix hydrolase family
CDO23_RS11890	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CDO23_RS11910	COG2274	protein secretion by the type I secretion system
CDO23_RS11915	COG2032	superoxide dismutase activity
CDO23_RS11925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CDO23_RS11930	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDO23_RS11945	COG1418	mRNA catabolic process
CDO23_RS11960	COG1381	Involved in DNA repair and RecF pathway recombination
CDO23_RS11965	COG1376	ErfK ybiS ycfS ynhG family protein
CDO23_RS11985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS11990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDO23_RS12000	COG2183	response to ionizing radiation
CDO23_RS12005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO23_RS12010	COG0584	glycerophosphoryl diester phosphodiesterase
CDO23_RS12030	COG0431	NADPH-dependent FMN reductase
CDO23_RS12035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDO23_RS12040	COG0571	ribonuclease III activity
CDO23_RS12045	COG0681	Belongs to the peptidase S26 family
CDO23_RS12050	COG0736	holo-[acyl-carrier-protein] synthase activity
CDO23_RS12080	COG1758	RNA polymerase activity
CDO23_RS12100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDO23_RS12105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO23_RS12110	COG0741	lytic transglycosylase activity
CDO23_RS12120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDO23_RS12125	COG4974	Belongs to the 'phage' integrase family
CDO23_RS12130	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDO23_RS12135	COG4974	Belongs to the 'phage' integrase family
CDO23_RS12140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDO23_RS12150	COG3549	Plasmid maintenance system killer
CDO23_RS12155	COG3093	addiction module antidote protein HigA
CDO23_RS12170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO23_RS12190	COG0625	glutathione transferase activity
CDO23_RS12205	COG1742	UPF0060 membrane protein
CDO23_RS12210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDO23_RS12220	COG0463	Glycosyl transferase, family 2
CDO23_RS12225	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO23_RS12235	COG1733	regulation of RNA biosynthetic process
CDO23_RS12245	COG4176	ABC-type proline glycine betaine transport system permease component
CDO23_RS12265	COG0443	Heat shock 70 kDa protein
CDO23_RS12270	COG1573	uracil-dna glycosylase
CDO23_RS12285	COG2814	Major facilitator Superfamily
CDO23_RS12295	COG0308	aminopeptidase N
CDO23_RS12300	COG2205	protein histidine kinase activity
CDO23_RS12300	COG2202	Pas domain
CDO23_RS12305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDO23_RS12310	COG2205	protein histidine kinase activity
CDO23_RS12315	COG0745	RESPONSE REGULATOR receiver
CDO23_RS12320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO23_RS12325	COG3088	subunit of a heme lyase
CDO23_RS12330	COG1138	Cytochrome C-type biogenesis protein
CDO23_RS12335	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CDO23_RS12340	COG4235	cytochrome complex assembly
CDO23_RS12375	COG2983	Belongs to the UPF0260 family
CDO23_RS12380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO23_RS12425	COG2205	protein histidine kinase activity
CDO23_RS12435	COG2166	iron-sulfur cluster assembly
CDO23_RS12440	COG4957	zinc ion binding
CDO23_RS12445	COG1320	monovalent cation:proton antiporter activity
CDO23_RS12450	COG2212	antiporter activity
CDO23_RS12455	COG1863	multisubunit Na H antiporter MnhE subunit
CDO23_RS12460	COG0651	ATP synthesis coupled electron transport
CDO23_RS12465	COG1006	Multisubunit Na H antiporter MnhC subunit
CDO23_RS12470	COG2111	Na H antiporter
CDO23_RS12475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO23_RS12475	COG2111	Na H antiporter
CDO23_RS12480	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO23_RS12495	COG1272	protein, Hemolysin III
CDO23_RS12510	COG2514	catechol 2,3-dioxygenase activity
CDO23_RS12525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CDO23_RS12530	COG4993	Dehydrogenase
CDO23_RS12540	COG0789	Transcriptional regulator
CDO23_RS12550	COG2010	Cytochrome c
CDO23_RS12575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDO23_RS12590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO23_RS12610	COG4106	trans-aconitate 2-methyltransferase activity
CDO23_RS12620	COG0656	L-ascorbic acid biosynthetic process
CDO23_RS12630	COG0433	COG0433 Predicted ATPase
CDO23_RS12635	COG2824	Alkylphosphonate utilization operon protein PhnA
CDO23_RS12640	COG1764	response to oxidative stress
CDO23_RS12645	COG1846	Transcriptional regulator
CDO23_RS12650	COG1388	LysM domain
CDO23_RS12650	COG1376	ErfK ybiS ycfS ynhG family protein
CDO23_RS12665	COG0583	DNA-binding transcription factor activity
CDO23_RS12690	COG0604	alcohol dehydrogenase
CDO23_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS12690	COG3321	synthase
CDO23_RS12695	COG5001	Diguanylate cyclase
CDO23_RS12695	COG3300	MHYT domain
CDO23_RS12705	COG1309	transcriptional regulator
CDO23_RS12710	COG3119	arylsulfatase activity
CDO23_RS12715	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS12720	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CDO23_RS12735	COG0175	sulfate reduction
CDO23_RS12740	COG0175	sulfate reduction
CDO23_RS12745	COG2895	sulfate adenylyltransferase (ATP) activity
CDO23_RS12770	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CDO23_RS12770	COG3264	Mechanosensitive ion channel
CDO23_RS12810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDO23_RS12810	COG0574	Belongs to the PEP-utilizing enzyme family
CDO23_RS12815	COG1196	nuclear chromosome segregation
CDO23_RS12835	COG1194	a g-specific adenine glycosylase
CDO23_RS12845	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CDO23_RS12855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO23_RS12875	COG0612	Peptidase, M16
CDO23_RS12880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO23_RS12885	COG5001	Diguanylate cyclase
CDO23_RS12890	COG3385	transposase activity
CDO23_RS12895	COG1678	Uncharacterized ACR, COG1678
CDO23_RS12905	COG0678	peroxiredoxin activity
CDO23_RS12905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDO23_RS12910	COG0328	RNA-DNA hybrid ribonuclease activity
CDO23_RS12915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDO23_RS12920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDO23_RS12925	COG3346	SURF1 family
CDO23_RS12945	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CDO23_RS12955	COG0109	protoheme IX farnesyltransferase activity
CDO23_RS12960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO23_RS12965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO23_RS12965	COG1565	acr, cog1565
CDO23_RS12980	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDO23_RS12980	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDO23_RS12985	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDO23_RS13000	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDO23_RS13005	COG0484	heat shock protein binding
CDO23_RS13015	COG0259	pyridoxamine-phosphate oxidase activity
CDO23_RS13035	COG0312	modulator of DNA gyrase
CDO23_RS13040	COG3214	Protein conserved in bacteria
CDO23_RS13045	COG1122	ATPase activity
CDO23_RS13050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDO23_RS13055	COG1268	BioY protein
CDO23_RS13060	COG0318	PFAM AMP-dependent synthetase and ligase
CDO23_RS13065	COG0183	Belongs to the thiolase family
CDO23_RS13075	COG1063	alcohol dehydrogenase
CDO23_RS13080	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDO23_RS13085	COG1722	exodeoxyribonuclease VII activity
CDO23_RS13090	COG1741	Belongs to the pirin family
CDO23_RS13095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDO23_RS13105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDO23_RS13125	COG1960	acyl-CoA dehydrogenase activity
CDO23_RS13145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDO23_RS13150	COG4638	Rieske (2fe-2S)
CDO23_RS13160	COG0009	L-threonylcarbamoyladenylate synthase
CDO23_RS13180	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDO23_RS13185	COG3713	MltA-interacting MipA family protein
CDO23_RS13190	COG4977	sequence-specific DNA binding
CDO23_RS13195	COG2223	nitrite transmembrane transporter activity
CDO23_RS13205	COG5001	Diguanylate cyclase
CDO23_RS13210	COG0151	Belongs to the GarS family
CDO23_RS13220	COG1683	Conserved Protein
CDO23_RS13225	COG0751	glycine-tRNA ligase activity
CDO23_RS13235	COG1704	LemA family
CDO23_RS13245	COG0752	glycyl-tRNA synthetase alpha subunit
CDO23_RS13270	COG0142	geranyltranstransferase activity
CDO23_RS13280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDO23_RS13285	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDO23_RS13305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDO23_RS13315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDO23_RS13320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDO23_RS13325	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDO23_RS13330	COG0356	it plays a direct role in the translocation of protons across the membrane
CDO23_RS13345	COG3158	transport of potassium into the cell
CDO23_RS13350	COG0598	Magnesium transport protein CorA
CDO23_RS13355	COG0489	protein tyrosine kinase activity
CDO23_RS13360	COG2771	luxR family
CDO23_RS13370	COG1414	Transcriptional regulator
CDO23_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS13380	COG3734	2-keto-3-deoxy-galactonokinase
CDO23_RS13385	COG0800	Aldolase
CDO23_RS13390	COG3386	PFAM SMP-30 Gluconolaconase
CDO23_RS13395	COG0129	dihydroxy-acid dehydratase activity
CDO23_RS13410	COG5598	trimethylamine methyltransferase
CDO23_RS13415	COG0583	DNA-binding transcription factor activity
CDO23_RS13420	COG5001	Diguanylate cyclase
CDO23_RS13420	COG3300	MHYT domain
CDO23_RS13430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDO23_RS13440	COG1663	tetraacyldisaccharide 4'-kinase activity
CDO23_RS13450	COG1519	Transferase
CDO23_RS13460	COG0483	inositol monophosphate 1-phosphatase activity
CDO23_RS13465	COG0312	modulator of DNA gyrase
CDO23_RS13470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO23_RS13470	COG0475	glutathione-regulated potassium exporter activity
CDO23_RS13485	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO23_RS13490	COG0742	ribosomal rna small subunit methyltransferase
CDO23_RS13495	COG1187	pseudouridine synthase activity
CDO23_RS13500	COG0590	tRNA wobble adenosine to inosine editing
CDO23_RS13515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDO23_RS13520	COG0196	riboflavin kinase activity
CDO23_RS13535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO23_RS13540	COG0459	protein refolding
CDO23_RS13555	COG0625	glutathione transferase activity
CDO23_RS13560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDO23_RS13565	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDO23_RS13570	COG0124	histidyl-tRNA synthetase
CDO23_RS13585	COG1953	Uracil, thiamine, allantoin
CDO23_RS13590	COG2818	Glycosylase
CDO23_RS13595	COG1376	ErfK ybiS ycfS ynhG family protein
CDO23_RS13600	COG1388	LysM domain
CDO23_RS13600	COG1376	ErfK ybiS ycfS ynhG family protein
CDO23_RS13605	COG0247	lactate metabolic process
CDO23_RS13610	COG0277	FAD linked oxidase domain protein
CDO23_RS13615	COG0277	FAD linked oxidase domain protein
CDO23_RS13620	COG0583	DNA-binding transcription factor activity
CDO23_RS13630	COG1725	Transcriptional regulator
CDO23_RS13640	COG0306	phosphate transporter
CDO23_RS13675	COG0583	DNA-binding transcription factor activity
CDO23_RS13680	COG0753	catalase activity
CDO23_RS13685	COG0583	DNA-binding transcription factor activity
CDO23_RS13690	COG0412	Dienelactone hydrolase
CDO23_RS13710	COG0477	Major facilitator Superfamily
CDO23_RS13720	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDO23_RS13755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDO23_RS13760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDO23_RS13785	COG1715	Restriction endonuclease
CDO23_RS13800	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDO23_RS13805	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDO23_RS13870	COG2059	Chromate
CDO23_RS13925	COG1285	pathogenesis
CDO23_RS13935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS13960	COG0784	Response regulator, receiver
CDO23_RS13975	COG0251	oxidation-reduction process
CDO23_RS13980	COG4608	Belongs to the ABC transporter superfamily
CDO23_RS13985	COG0444	Belongs to the ABC transporter superfamily
CDO23_RS13990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS13995	COG0601	transmembrane transport
CDO23_RS14000	COG0747	negative chemotaxis
CDO23_RS14005	COG1959	2 iron, 2 sulfur cluster binding
CDO23_RS14010	COG1840	ABC-type Fe3 transport system, periplasmic component
CDO23_RS14020	COG4269	membrane
CDO23_RS14055	COG2205	protein histidine kinase activity
CDO23_RS14060	COG1178	ABC-type Fe3 transport system permease component
CDO23_RS14065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO23_RS14080	COG1177	transmembrane transport
CDO23_RS14085	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO23_RS14090	COG3842	ATPase activity
CDO23_RS14105	COG2224	Isocitrate lyase
CDO23_RS14175	COG0840	transmembrane signaling receptor activity
CDO23_RS14175	COG2972	Histidine kinase
CDO23_RS14185	COG2081	HI0933 family
CDO23_RS14195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS14200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDO23_RS14205	COG0363	glucosamine-6-phosphate deaminase activity
CDO23_RS14210	COG0129	dihydroxy-acid dehydratase activity
CDO23_RS14220	COG3842	ATPase activity
CDO23_RS14225	COG0366	Alpha amylase catalytic
CDO23_RS14230	COG0395	ABC-type sugar transport system, permease component
CDO23_RS14235	COG1175	transmembrane transport
CDO23_RS14240	COG1653	transport
CDO23_RS14245	COG1609	Transcriptional regulator
CDO23_RS14250	COG3328	transposase activity
CDO23_RS14255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDO23_RS14290	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO23_RS14295	COG4794	Type iii secretion
CDO23_RS14300	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CDO23_RS14305	COG5443	negative regulation of bacterial-type flagellum assembly
CDO23_RS14325	COG1749	Flagellar hook protein flgE
CDO23_RS14350	COG1360	Flagellar Motor Protein
CDO23_RS14360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO23_RS14375	COG1338	Plays a role in the flagellum-specific transport system
CDO23_RS14385	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CDO23_RS14395	COG1706	bacterial-type flagellum-dependent cell motility
CDO23_RS14400	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CDO23_RS14405	COG4786	Flagellar basal body rod
CDO23_RS14410	COG1677	Flagellar hook-basal body complex protein FliE
CDO23_RS14415	COG1558	bacterial-type flagellum-dependent cell motility
CDO23_RS14420	COG1815	bacterial-type flagellum-dependent cell motility
CDO23_RS14430	COG1157	protein secretion by the type III secretion system
CDO23_RS14435	COG4786	Flagellar basal body rod
CDO23_RS14445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDO23_RS14450	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO23_RS14455	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO23_RS14460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO23_RS14465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO23_RS14480	COG2771	luxR family
CDO23_RS14485	COG1766	The M ring may be actively involved in energy transduction
CDO23_RS14495	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CDO23_RS14500	COG0745	RESPONSE REGULATOR receiver
CDO23_RS14505	COG2201	protein-glutamate methylesterase activity
CDO23_RS14510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CDO23_RS14515	COG0835	chemotaxis
CDO23_RS14520	COG0643	Histidine kinase
CDO23_RS14520	COG2198	Histidine kinase
CDO23_RS14525	COG0745	RESPONSE REGULATOR receiver
CDO23_RS14535	COG0840	transmembrane signaling receptor activity
CDO23_RS14545	COG3254	rhamnose metabolic process
CDO23_RS14555	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS14560	COG1129	ABC transporter
CDO23_RS14570	COG1349	DNA-binding transcription factor activity
CDO23_RS14575	COG3347	Dehydrogenase
CDO23_RS14575	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS14580	COG4952	isomerase
CDO23_RS14595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDO23_RS14635	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDO23_RS14640	COG0424	maF-like protein
CDO23_RS14645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDO23_RS14655	COG5328	Belongs to the UPF0262 family
CDO23_RS14660	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDO23_RS14670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDO23_RS14700	COG2132	Multicopper oxidase
CDO23_RS14730	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDO23_RS14735	COG1335	isochorismatase
CDO23_RS14750	COG0156	8-amino-7-oxononanoate synthase activity
CDO23_RS14755	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS14760	COG1368	sulfuric ester hydrolase activity
CDO23_RS14770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDO23_RS14770	COG0517	IMP dehydrogenase activity
CDO23_RS14775	COG1959	2 iron, 2 sulfur cluster binding
CDO23_RS14805	COG1309	transcriptional regulator
CDO23_RS14815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO23_RS14820	COG4215	(ABC) transporter
CDO23_RS14830	COG1473	amidohydrolase
CDO23_RS14835	COG1271	oxidase subunit
CDO23_RS14840	COG1294	oxidase, subunit
CDO23_RS14855	COG0436	Aminotransferase
CDO23_RS14860	COG1970	mechanosensitive ion channel activity
CDO23_RS14885	COG0167	dihydroorotate dehydrogenase activity
CDO23_RS14890	COG0534	Mate efflux family protein
CDO23_RS14915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO23_RS14920	COG1959	2 iron, 2 sulfur cluster binding
CDO23_RS14925	COG1201	RNA secondary structure unwinding
CDO23_RS14950	COG0730	response to heat
CDO23_RS14960	COG1960	acyl-CoA dehydrogenase activity
CDO23_RS14965	COG0183	Belongs to the thiolase family
CDO23_RS14970	COG1024	Enoyl-CoA hydratase
CDO23_RS14970	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO23_RS14990	COG0387	Pfam Sodium calcium exchanger
CDO23_RS14995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDO23_RS15015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO23_RS15025	COG0717	Belongs to the dCTP deaminase family
CDO23_RS15035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDO23_RS15040	COG2967	ApaG domain
CDO23_RS15050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDO23_RS15055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO23_RS15065	COG0745	RESPONSE REGULATOR receiver
CDO23_RS15070	COG0704	Plays a role in the regulation of phosphate uptake
CDO23_RS15075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDO23_RS15085	COG0573	inorganic phosphate transmembrane transporter activity
CDO23_RS15095	COG5002	protein histidine kinase activity
CDO23_RS15100	COG2326	polyphosphate kinase activity
CDO23_RS15130	COG4589	Belongs to the CDS family
CDO23_RS15145	COG0628	permease
CDO23_RS15150	COG2814	Major facilitator Superfamily
CDO23_RS15155	COG0318	PFAM AMP-dependent synthetase and ligase
CDO23_RS15160	COG0166	Belongs to the GPI family
CDO23_RS15170	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDO23_RS15175	COG0418	dihydroorotase activity
CDO23_RS15180	COG1072	(Pantothenic acid kinase))
CDO23_RS15215	COG2259	Doxx family
CDO23_RS15225	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS15260	COG0667	Aldo Keto reductase
CDO23_RS15315	COG1304	FMN binding
CDO23_RS15355	COG5002	protein histidine kinase activity
CDO23_RS15380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CDO23_RS15385	COG0594	ribonuclease P activity
CDO23_RS15390	COG0706	membrane insertase activity
CDO23_RS15400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDO23_RS15410	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO23_RS15420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDO23_RS15430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO23_RS15430	COG2169	Transcriptional regulator
CDO23_RS15450	COG2171	N-acyltransferase activity
CDO23_RS15460	COG0513	Belongs to the DEAD box helicase family
CDO23_RS15470	COG1733	regulation of RNA biosynthetic process
CDO23_RS15475	COG0583	DNA-binding transcription factor activity
CDO23_RS15480	COG0657	acetylesterase activity
CDO23_RS15495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO23_RS15505	COG0101	tRNA pseudouridine synthase activity
CDO23_RS15510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO23_RS15515	COG0242	peptide deformylase activity
CDO23_RS15525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO23_RS15530	COG0840	transmembrane signaling receptor activity
CDO23_RS15535	COG1957	nucleoside hydrolase
CDO23_RS15540	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO23_RS15550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDO23_RS15555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDO23_RS15560	COG1396	sequence-specific DNA binding
CDO23_RS15565	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CDO23_RS15570	COG4535	Mg2 and Co2 transporter CorC
CDO23_RS15575	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDO23_RS15580	COG1702	phosphate starvation-inducible protein PhoH
CDO23_RS15585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDO23_RS15605	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDO23_RS15615	COG0180	Tryptophanyl-tRNA synthetase
CDO23_RS15625	COG0728	peptidoglycan biosynthetic process
CDO23_RS15630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CDO23_RS15635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDO23_RS15640	COG0280	phosphate acetyltransferase
CDO23_RS15640	COG0281	malic enzyme
CDO23_RS15650	COG2205	protein histidine kinase activity
CDO23_RS15650	COG5002	protein histidine kinase activity
CDO23_RS15650	COG0784	Response regulator, receiver
CDO23_RS15655	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDO23_RS15660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO23_RS15665	COG0116	Belongs to the methyltransferase superfamily
CDO23_RS15665	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDO23_RS15680	COG0776	regulation of translation
CDO23_RS15685	COG0616	signal peptide processing
CDO23_RS15695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDO23_RS15700	COG1137	ATPase activity
CDO23_RS15705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO23_RS15710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDO23_RS15715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO23_RS15720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDO23_RS15725	COG1420	regulation of RNA biosynthetic process
CDO23_RS15730	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDO23_RS15740	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDO23_RS15745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDO23_RS15760	COG4941	Belongs to the sigma-70 factor family
CDO23_RS15765	COG3795	YCII-related domain
CDO23_RS15770	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDO23_RS15780	COG0268	Binds directly to 16S ribosomal RNA
CDO23_RS15785	COG1024	Enoyl-CoA hydratase
CDO23_RS15790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDO23_RS15795	COG2226	methyltransferase
CDO23_RS15800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDO23_RS15805	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS15830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDO23_RS15865	COG3718	enzyme involved in inositol metabolism
CDO23_RS15875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS15890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDO23_RS15895	COG0756	dUTP diphosphatase activity
CDO23_RS15900	COG1522	sequence-specific DNA binding
CDO23_RS15905	COG0697	spore germination
CDO23_RS15920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDO23_RS15940	COG0189	ligase activity
CDO23_RS15945	COG0792	nuclease activity
CDO23_RS15950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDO23_RS15960	COG3963	phosphatidate phosphatase activity
CDO23_RS15970	COG0284	orotidine-5'-phosphate decarboxylase activity
CDO23_RS15980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS15990	COG1968	undecaprenyl-diphosphatase activity
CDO23_RS16000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDO23_RS16010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDO23_RS16045	COG1247	-acetyltransferase
CDO23_RS16060	COG0519	Catalyzes the synthesis of GMP from XMP
CDO23_RS16060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDO23_RS16095	COG1448	Aminotransferase
CDO23_RS16100	COG1393	Belongs to the ArsC family
CDO23_RS16115	COG0625	glutathione transferase activity
CDO23_RS16120	COG2309	aminopeptidase activity
CDO23_RS16135	COG0697	spore germination
CDO23_RS16140	COG1846	Transcriptional regulator
CDO23_RS16145	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDO23_RS16150	COG1570	exodeoxyribonuclease VII activity
CDO23_RS16170	COG0667	Aldo Keto reductase
CDO23_RS16195	COG0667	Aldo Keto reductase
CDO23_RS16205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO23_RS16205	COG0072	phenylalanine-tRNA ligase activity
CDO23_RS16210	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDO23_RS16215	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDO23_RS16220	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDO23_RS16225	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDO23_RS16245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO23_RS16250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDO23_RS16255	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CDO23_RS16260	COG1509	lysine 2,3-aminomutase activity
CDO23_RS16265	COG2885	chlorophyll binding
CDO23_RS16270	COG3932	Exopolysaccharide synthesis, ExoD
CDO23_RS16290	COG0481	GTPase activity
CDO23_RS16300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO23_RS16335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO23_RS16340	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS16365	COG0539	negative regulation of cytoplasmic translation
CDO23_RS16370	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDO23_RS16375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDO23_RS16395	COG2860	membrane
CDO23_RS16405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO23_RS16415	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDO23_RS16425	COG1185	polyribonucleotide nucleotidyltransferase activity
CDO23_RS16430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDO23_RS16440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDO23_RS16445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDO23_RS16450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDO23_RS16460	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDO23_RS16460	COG0195	Participates in both transcription termination and antitermination
CDO23_RS16465	COG0779	Required for maturation of 30S ribosomal subunits
CDO23_RS16470	COG2814	Major facilitator Superfamily
CDO23_RS16475	COG2951	lytic endotransglycosylase activity
CDO23_RS16480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDO23_RS16490	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDO23_RS16495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDO23_RS16510	COG2816	NAD+ diphosphatase activity
CDO23_RS16515	COG2378	regulation of single-species biofilm formation
CDO23_RS16530	COG0077	Prephenate dehydratase
CDO23_RS16530	COG1605	Chorismate mutase
CDO23_RS16535	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CDO23_RS16540	COG3474	cytochrome
CDO23_RS16545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO23_RS16565	COG2814	Major facilitator Superfamily
CDO23_RS16575	COG4771	TonB-dependent receptor
CDO23_RS16580	COG2814	Major facilitator Superfamily
CDO23_RS16640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO23_RS16645	COG1744	ABC transporter substrate-binding protein PnrA-like
CDO23_RS16650	COG2900	Belongs to the SlyX family
CDO23_RS16670	COG1940	carbohydrate kinase activity
CDO23_RS16675	COG3142	Participates in the control of copper homeostasis
CDO23_RS16680	COG3328	transposase activity
CDO23_RS16685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDO23_RS16690	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO23_RS16695	COG2188	Transcriptional regulator
CDO23_RS16700	COG2971	BadF BadG BcrA BcrD
CDO23_RS16705	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDO23_RS16715	COG1175	transmembrane transport
CDO23_RS16720	COG0395	ABC-type sugar transport system, permease component
CDO23_RS16725	COG0673	inositol 2-dehydrogenase activity
CDO23_RS16735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO23_RS16740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO23_RS16760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDO23_RS16765	COG1392	Phosphate transport regulator
CDO23_RS16770	COG0306	phosphate transporter
CDO23_RS16785	COG0484	heat shock protein binding
CDO23_RS16790	COG0443	Heat shock 70 kDa protein
CDO23_RS16795	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO23_RS16820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO23_RS16830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO23_RS16830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO23_RS16850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO23_RS16860	COG1309	transcriptional regulator
CDO23_RS16875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO23_RS16880	COG0588	phosphoglycerate mutase activity
CDO23_RS16885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDO23_RS16890	COG1132	(ABC) transporter
CDO23_RS16895	COG0837	glucose binding
CDO23_RS16900	COG1803	Methylglyoxal synthase
CDO23_RS16905	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CDO23_RS16910	COG4166	transmembrane transport
CDO23_RS16915	COG4174	ABC transporter (Permease)
CDO23_RS16920	COG4239	(ABC) transporter, permease
CDO23_RS16925	COG4172	Belongs to the ABC transporter superfamily
CDO23_RS16935	COG3385	transposase activity
CDO23_RS16940	COG0791	NLP P60 protein
CDO23_RS16950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO23_RS16985	COG4964	Belongs to the GSP D family
CDO23_RS17020	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CDO23_RS17025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDO23_RS17030	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDO23_RS17035	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CDO23_RS17050	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS17055	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS17060	COG3845	ABC transporter
CDO23_RS17070	COG0673	inositol 2-dehydrogenase activity
CDO23_RS17090	COG0673	inositol 2-dehydrogenase activity
CDO23_RS17095	COG1309	transcriptional regulator
CDO23_RS17100	COG1653	transport
CDO23_RS17105	COG1175	transmembrane transport
CDO23_RS17110	COG0395	ABC-type sugar transport system, permease component
CDO23_RS17115	COG0673	inositol 2-dehydrogenase activity
CDO23_RS17120	COG0673	inositol 2-dehydrogenase activity
CDO23_RS17125	COG3842	ATPase activity
CDO23_RS17140	COG2186	Transcriptional regulator
CDO23_RS17150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS17155	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CDO23_RS17165	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO23_RS17190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO23_RS17220	COG0531	amino acid
CDO23_RS17235	COG0174	glutamine synthetase
CDO23_RS17240	COG0069	glutamate synthase activity
CDO23_RS17245	COG2218	PFAM glutamate synthase alpha subunit domain protein
CDO23_RS17250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDO23_RS17255	COG4977	sequence-specific DNA binding
CDO23_RS17260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS17265	COG4311	Sarcosine oxidase, delta subunit
CDO23_RS17270	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO23_RS17270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO23_RS17280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDO23_RS17285	COG3119	arylsulfatase activity
CDO23_RS17310	COG0626	cystathionine gamma-synthase activity
CDO23_RS17315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDO23_RS17375	COG4134	Bacterial extracellular solute-binding protein
CDO23_RS17380	COG4135	transport system, permease component
CDO23_RS17385	COG4136	ATPase activity
CDO23_RS17390	COG1643	Atp-dependent helicase
CDO23_RS17400	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CDO23_RS17415	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDO23_RS17425	COG2124	cytochrome p450
CDO23_RS17435	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CDO23_RS17445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CDO23_RS17450	COG0131	Imidazoleglycerol-phosphate dehydratase
CDO23_RS17460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDO23_RS17465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDO23_RS17470	COG0107	imidazoleglycerol-phosphate synthase activity
CDO23_RS17475	COG0140	phosphoribosyl-ATP diphosphatase activity
CDO23_RS17480	COG1072	(Pantothenic acid kinase))
CDO23_RS17485	COG3547	Transposase (IS116 IS110 IS902 family)
CDO23_RS17490	COG3328	transposase activity
CDO23_RS17500	COG1652	LysM domain
CDO23_RS17510	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CDO23_RS17515	COG0745	RESPONSE REGULATOR receiver
CDO23_RS17520	COG2205	protein histidine kinase activity
CDO23_RS17535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO23_RS17535	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO23_RS17545	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDO23_RS17550	COG2205	protein histidine kinase activity
CDO23_RS17555	COG3178	'Phosphotransferase
CDO23_RS17560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDO23_RS17565	COG2887	Belongs to the helicase family. UvrD subfamily
CDO23_RS17570	COG1074	ATP-dependent DNA helicase activity
CDO23_RS17580	COG3385	transposase activity
CDO23_RS17590	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDO23_RS17595	COG0159	tryptophan synthase activity
CDO23_RS17600	COG0133	tryptophan synthase activity
CDO23_RS17605	COG0135	phosphoribosylanthranilate isomerase activity
CDO23_RS17625	COG1063	alcohol dehydrogenase
CDO23_RS17630	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS17650	COG2721	sulfolactate sulfo-lyase activity
CDO23_RS17655	COG1802	Transcriptional regulator
CDO23_RS17705	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CDO23_RS17710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDO23_RS17715	COG0237	dephospho-CoA kinase activity
CDO23_RS17720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDO23_RS17725	COG0424	maF-like protein
CDO23_RS17730	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDO23_RS17735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDO23_RS17740	COG1981	membrane
CDO23_RS17745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDO23_RS17750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDO23_RS17755	COG0445	tRNA wobble uridine modification
CDO23_RS17760	COG0357	Ribosomal RNA small subunit methyltransferase G
CDO23_RS17785	COG0495	leucyl-tRNA aminoacylation
CDO23_RS17805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO23_RS17815	COG0501	Belongs to the peptidase M48B family
CDO23_RS17820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDO23_RS17820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO23_RS17830	COG0138	bifunctional purine biosynthesis protein purh
CDO23_RS17845	COG2902	Dehydrogenase
CDO23_RS17855	COG0288	reversible hydration of carbon dioxide
CDO23_RS17865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDO23_RS17885	COG0671	phosphoesterase, PA-phosphatase related
CDO23_RS17890	COG0473	3-isopropylmalate dehydrogenase activity
CDO23_RS17900	COG0339	signal peptide processing
CDO23_RS17910	COG1609	Transcriptional regulator
CDO23_RS17915	COG0673	inositol 2-dehydrogenase activity
CDO23_RS17925	COG1024	Enoyl-CoA hydratase
CDO23_RS17930	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS17935	COG1653	transport
CDO23_RS17940	COG1175	transmembrane transport
CDO23_RS17945	COG0395	ABC-type sugar transport system, permease component
CDO23_RS17950	COG3842	ATPase activity
CDO23_RS17975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO23_RS17985	COG3385	transposase activity
CDO23_RS17990	COG0436	Aminotransferase
CDO23_RS18005	COG5383	Protein conserved in bacteria
CDO23_RS18035	COG0741	lytic transglycosylase activity
CDO23_RS18040	COG3451	type IV secretory pathway VirB4
CDO23_RS18050	COG3838	Conjugal transfer protein Trbc
CDO23_RS18055	COG0741	lytic transglycosylase activity
CDO23_RS18140	COG1278	Cold shock
CDO23_RS18245	COG3328	transposase activity
CDO23_RS18270	COG0785	Cytochrome C biogenesis protein
CDO23_RS18275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDO23_RS18275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDO23_RS18280	COG1999	signal sequence binding
CDO23_RS18290	COG2132	Multicopper oxidase
CDO23_RS18305	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO23_RS18350	COG0789	Transcriptional regulator
CDO23_RS18355	COG1309	transcriptional regulator
CDO23_RS18400	COG1238	metal cluster binding
CDO23_RS18445	COG1376	ErfK ybiS ycfS ynhG family protein
CDO23_RS18455	COG1475	DNA binding
CDO23_RS18485	COG4227	nucleotidyltransferase activity
CDO23_RS18490	COG1192	Involved in chromosome partitioning
CDO23_RS18495	COG1475	DNA binding
CDO23_RS18500	COG0640	Transcriptional regulator
CDO23_RS18560	COG0517	IMP dehydrogenase activity
CDO23_RS18565	COG4974	Belongs to the 'phage' integrase family
CDO23_RS18575	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDO23_RS18580	COG4584	PFAM Integrase catalytic
CDO23_RS18600	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CDO23_RS18605	COG0631	protein serine/threonine phosphatase activity
CDO23_RS18610	COG4245	von Willebrand factor, type A
CDO23_RS18615	COG3429	Glucose-6-phosphate dehydrogenase subunit
CDO23_RS18615	COG3409	Peptidoglycan-binding domain 1 protein
CDO23_RS18625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDO23_RS18650	COG2267	carboxylic ester hydrolase activity
CDO23_RS18675	COG1129	ABC transporter
CDO23_RS18680	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS18685	COG1737	Transcriptional regulator
CDO23_RS18700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO23_RS18710	COG0765	amino acid transport
CDO23_RS18720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO23_RS18725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO23_RS18730	COG1063	alcohol dehydrogenase
CDO23_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS18745	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS18745	COG1672	PFAM Archaeal ATPase
CDO23_RS18750	COG0784	Response regulator, receiver
CDO23_RS18755	COG1295	ribonuclease BN
CDO23_RS18765	COG2239	Acts as a magnesium transporter
CDO23_RS18790	COG3920	Histidine kinase
CDO23_RS18795	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CDO23_RS18850	COG3831	ATPase activity
CDO23_RS18895	COG1073	alpha beta
CDO23_RS18925	COG1484	DNA-dependent DNA replication
CDO23_RS18930	COG4584	PFAM Integrase catalytic
CDO23_RS18935	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS18945	COG0667	Aldo Keto reductase
CDO23_RS18950	COG0667	Aldo Keto reductase
CDO23_RS18955	COG0667	Aldo Keto reductase
CDO23_RS18970	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CDO23_RS19035	COG4372	Transposase
CDO23_RS19045	COG0583	DNA-binding transcription factor activity
CDO23_RS19125	COG0693	protein deglycase activity
CDO23_RS19130	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS19135	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS19140	COG1129	ABC transporter
CDO23_RS19145	COG1802	Transcriptional regulator
CDO23_RS19150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CDO23_RS19155	COG1454	alcohol dehydrogenase
CDO23_RS19165	COG0657	acetylesterase activity
CDO23_RS19185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS19190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS19195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO23_RS19205	COG2186	Transcriptional regulator
CDO23_RS19210	COG0277	FAD linked oxidase domain protein
CDO23_RS19215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS19220	COG2084	Dehydrogenase
CDO23_RS19225	COG0129	dihydroxy-acid dehydratase activity
CDO23_RS19230	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CDO23_RS19240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO23_RS19250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDO23_RS19270	COG1802	Transcriptional regulator
CDO23_RS19275	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS19290	COG1129	ABC transporter
CDO23_RS19320	COG4585	Histidine kinase
CDO23_RS19325	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS19330	COG1129	ABC transporter
CDO23_RS19335	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS19380	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS19385	COG0477	Major facilitator Superfamily
CDO23_RS19390	COG1278	Cold shock
CDO23_RS19435	COG4106	trans-aconitate 2-methyltransferase activity
CDO23_RS19455	COG4964	Belongs to the GSP D family
CDO23_RS19460	COG1802	Transcriptional regulator
CDO23_RS19465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS19485	COG0318	PFAM AMP-dependent synthetase and ligase
CDO23_RS19490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO23_RS19515	COG1404	Belongs to the peptidase S8 family
CDO23_RS19525	COG5001	Diguanylate cyclase
CDO23_RS19525	COG3300	MHYT domain
CDO23_RS19530	COG0628	permease
CDO23_RS19550	COG3239	Fatty acid desaturase
CDO23_RS19560	COG1278	Cold shock
CDO23_RS19625	COG1487	ribonuclease activity
CDO23_RS19630	COG4691	Plasmid stability protein
CDO23_RS19640	COG0444	Belongs to the ABC transporter superfamily
CDO23_RS19645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS19650	COG0601	transmembrane transport
CDO23_RS19655	COG0747	negative chemotaxis
CDO23_RS19660	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO23_RS19665	COG0583	DNA-binding transcription factor activity
CDO23_RS19685	COG0251	oxidation-reduction process
CDO23_RS19695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO23_RS19700	COG1126	abc transporter atp-binding protein
CDO23_RS19705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO23_RS19710	COG0765	amino acid transport
CDO23_RS19715	COG0765	amino acid transport
CDO23_RS19720	COG1609	Transcriptional regulator
CDO23_RS19750	COG1802	Transcriptional regulator
CDO23_RS19760	COG2186	Transcriptional regulator
CDO23_RS19775	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS19785	COG4948	Mandelate Racemase Muconate Lactonizing
CDO23_RS19790	COG1129	ABC transporter
CDO23_RS19800	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS19805	COG1024	Enoyl-CoA hydratase
CDO23_RS19815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDO23_RS19820	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS19840	COG1609	Transcriptional regulator
CDO23_RS19855	COG0583	DNA-binding transcription factor activity
CDO23_RS19860	COG0488	(ABC) transporter
CDO23_RS19885	COG1305	Transglutaminase-like
CDO23_RS19945	COG2864	formate dehydrogenase
CDO23_RS19950	COG0437	4 iron, 4 sulfur cluster binding
CDO23_RS19960	COG1192	Involved in chromosome partitioning
CDO23_RS19965	COG1475	DNA binding
CDO23_RS19970	COG1414	Transcriptional regulator
CDO23_RS19975	COG1764	response to oxidative stress
CDO23_RS19985	COG0488	(ABC) transporter
CDO23_RS19995	COG1309	transcriptional regulator
CDO23_RS20020	COG0402	S-adenosylhomocysteine deaminase activity
CDO23_RS20025	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS20030	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS20035	COG3845	ABC transporter
CDO23_RS20050	COG0730	response to heat
CDO23_RS20075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS20080	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO23_RS20085	COG2080	2 iron, 2 sulfur cluster binding
CDO23_RS20105	COG4221	oxidoreductase activity
CDO23_RS20190	COG2205	protein histidine kinase activity
CDO23_RS20215	COG0418	dihydroorotase activity
CDO23_RS20245	COG0778	Nitroreductase
CDO23_RS20245	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CDO23_RS20250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CDO23_RS20255	COG1920	GTP binding
CDO23_RS20260	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CDO23_RS20270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDO23_RS20280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO23_RS20320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO23_RS20325	COG2188	Transcriptional regulator
CDO23_RS20350	COG0395	ABC-type sugar transport system, permease component
CDO23_RS20370	COG3706	GGDEF domain
CDO23_RS20370	COG5001	Diguanylate cyclase
CDO23_RS20370	COG2203	Gaf domain
CDO23_RS20370	COG4251	negative regulation of phosphorylation
CDO23_RS20400	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO23_RS20410	COG1902	pentaerythritol trinitrate reductase activity
CDO23_RS20415	COG0251	oxidation-reduction process
CDO23_RS20420	COG0583	DNA-binding transcription factor activity
CDO23_RS20525	COG2801	Transposase and inactivated derivatives
CDO23_RS20560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDO23_RS20585	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO23_RS20590	COG3609	addiction module antidote protein, CC2985 family
CDO23_RS20630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDO23_RS20645	COG2910	NAD(P)H-binding
CDO23_RS20650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO23_RS20665	COG1960	acyl-CoA dehydrogenase activity
CDO23_RS20680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS20695	COG0667	Aldo Keto reductase
CDO23_RS20725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDO23_RS20740	COG3920	Histidine kinase
CDO23_RS20745	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CDO23_RS20795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO23_RS20800	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CDO23_RS20810	COG1744	ABC transporter substrate-binding protein PnrA-like
CDO23_RS20815	COG3845	ABC transporter
CDO23_RS20820	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS20825	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS20835	COG1957	nucleoside hydrolase
CDO23_RS20920	COG4191	Histidine kinase
CDO23_RS20925	COG4566	intracellular signal transduction
CDO23_RS20930	COG4566	intracellular signal transduction
CDO23_RS20935	COG4974	Belongs to the 'phage' integrase family
CDO23_RS20940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDO23_RS20960	COG3119	arylsulfatase activity
CDO23_RS20985	COG0668	transmembrane transport
CDO23_RS21015	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS21015	COG1672	PFAM Archaeal ATPase
CDO23_RS21045	COG0601	transmembrane transport
CDO23_RS21050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS21055	COG0444	Belongs to the ABC transporter superfamily
CDO23_RS21060	COG4608	Belongs to the ABC transporter superfamily
CDO23_RS21065	COG1473	amidohydrolase
CDO23_RS21085	COG1116	anion transmembrane transporter activity
CDO23_RS21095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO23_RS21110	COG3550	peptidyl-serine autophosphorylation
CDO23_RS21160	COG3278	Belongs to the heme-copper respiratory oxidase family
CDO23_RS21175	COG2010	Cytochrome c
CDO23_RS21215	COG0668	transmembrane transport
CDO23_RS21235	COG3005	denitrification pathway
CDO23_RS21260	COG0628	permease
CDO23_RS21295	COG0531	amino acid
CDO23_RS21300	COG1982	Orn Lys Arg decarboxylase major
CDO23_RS21315	COG0531	amino acid
CDO23_RS21370	COG3734	2-keto-3-deoxy-galactonokinase
CDO23_RS21375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO23_RS21380	COG4948	Mandelate Racemase Muconate Lactonizing
CDO23_RS21385	COG1653	transport
CDO23_RS21390	COG1175	transmembrane transport
CDO23_RS21395	COG0395	ABC-type sugar transport system, permease component
CDO23_RS21410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS21445	COG1349	DNA-binding transcription factor activity
CDO23_RS21465	COG3328	transposase activity
CDO23_RS21510	COG4584	PFAM Integrase catalytic
CDO23_RS21580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO23_RS21625	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS21650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDO23_RS21655	COG0527	aspartate kinase activity
CDO23_RS21665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDO23_RS21675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDO23_RS21680	COG0492	ferredoxin-NADP+ reductase activity
CDO23_RS21690	COG0459	protein refolding
CDO23_RS21710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS21735	COG0601	transmembrane transport
CDO23_RS21740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS21745	COG4172	Belongs to the ABC transporter superfamily
CDO23_RS21755	COG5328	Belongs to the UPF0262 family
CDO23_RS21765	COG3842	ATPase activity
CDO23_RS21770	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO23_RS21780	COG3608	succinylglutamate desuccinylase aspartoacylase
CDO23_RS21800	COG1414	Transcriptional regulator
CDO23_RS21810	COG2433	Pfam Transposase IS66
CDO23_RS21840	COG0517	IMP dehydrogenase activity
CDO23_RS21845	COG4974	Belongs to the 'phage' integrase family
CDO23_RS21860	COG1024	Enoyl-CoA hydratase
CDO23_RS21870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDO23_RS21885	COG3328	transposase activity
CDO23_RS21895	COG3328	transposase activity
CDO23_RS21905	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO23_RS21915	COG1509	lysine 2,3-aminomutase activity
CDO23_RS21940	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO23_RS22040	COG2010	Cytochrome c
CDO23_RS22090	COG2267	carboxylic ester hydrolase activity
CDO23_RS22100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO23_RS22105	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS22125	COG0395	ABC-type sugar transport system, permease component
CDO23_RS22200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO23_RS22210	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDO23_RS22215	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDO23_RS22225	COG1433	Dinitrogenase iron-molybdenum cofactor
CDO23_RS22230	COG5420	small protein containing a coiled-coil domain
CDO23_RS22235	COG3383	formate dehydrogenase (NAD+) activity
CDO23_RS22315	COG0175	sulfate reduction
CDO23_RS22320	COG2895	sulfate adenylyltransferase (ATP) activity
CDO23_RS22320	COG0529	Catalyzes the synthesis of activated sulfate
CDO23_RS22390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO23_RS22425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO23_RS22450	COG3012	SEC-C Motif Domain Protein
CDO23_RS22530	COG3505	Type IV secretory pathway VirD4
CDO23_RS22550	COG0668	transmembrane transport
CDO23_RS22585	COG1177	transmembrane transport
CDO23_RS22590	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO23_RS22595	COG3842	ATPase activity
CDO23_RS22605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDO23_RS22620	COG3328	transposase activity
CDO23_RS22625	COG0745	RESPONSE REGULATOR receiver
CDO23_RS22645	COG0156	8-amino-7-oxononanoate synthase activity
CDO23_RS22660	COG2826	transposase and inactivated derivatives, IS30 family
CDO23_RS22710	COG0583	DNA-binding transcription factor activity
CDO23_RS22715	COG0667	Aldo Keto reductase
CDO23_RS22735	COG0583	DNA-binding transcription factor activity
CDO23_RS22915	COG3005	denitrification pathway
CDO23_RS22940	COG4459	periplasmic nitrate reductase
CDO23_RS22950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO23_RS22975	COG2151	metal-sulfur cluster biosynthetic enzyme
CDO23_RS23010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDO23_RS23020	COG0714	Associated with various cellular activities
CDO23_RS23025	COG3256	nitric oxide reductase
CDO23_RS23040	COG1845	cytochrome c oxidase, subunit III
CDO23_RS23065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CDO23_RS23075	COG0826	peptidase U32
CDO23_RS23080	COG0826	peptidase U32
CDO23_RS23105	COG1309	transcriptional regulator
CDO23_RS23110	COG2814	Major facilitator Superfamily
CDO23_RS23115	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CDO23_RS23120	COG2948	multi-organism process
CDO23_RS23125	COG3504	Conjugal transfer protein
CDO23_RS23130	COG3736	Type IV secretory pathway, component VirB8
CDO23_RS23140	COG3704	protein secretion by the type IV secretion system
CDO23_RS23155	COG3451	type IV secretory pathway VirB4
CDO23_RS23160	COG3702	type iv secretory pathway
CDO23_RS23165	COG3838	Conjugal transfer protein Trbc
CDO23_RS23200	COG0477	Major facilitator Superfamily
CDO23_RS23215	COG5564	TIM-barrel signal transduction protein
CDO23_RS23235	COG1175	transmembrane transport
CDO23_RS23250	COG3842	ATPase activity
CDO23_RS23255	COG3842	ATPase activity
CDO23_RS23260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO23_RS23270	COG4948	Mandelate Racemase Muconate Lactonizing
CDO23_RS23275	COG1082	Xylose isomerase domain protein TIM barrel
CDO23_RS23280	COG1082	Xylose isomerase domain protein TIM barrel
CDO23_RS23300	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO23_RS23315	COG0395	ABC-type sugar transport system, permease component
CDO23_RS23320	COG1175	transmembrane transport
CDO23_RS23340	COG0444	Belongs to the ABC transporter superfamily
CDO23_RS23355	COG4608	Belongs to the ABC transporter superfamily
CDO23_RS23360	COG0444	Belongs to the ABC transporter superfamily
CDO23_RS23365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS23370	COG0601	transmembrane transport
CDO23_RS23380	COG0154	amidase activity
CDO23_RS23390	COG0747	negative chemotaxis
CDO23_RS23415	COG4172	Belongs to the ABC transporter superfamily
CDO23_RS23420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS23425	COG0601	transmembrane transport
CDO23_RS23430	COG0747	negative chemotaxis
CDO23_RS23440	COG2186	Transcriptional regulator
CDO23_RS23450	COG0477	Major facilitator Superfamily
CDO23_RS23460	COG0183	Belongs to the thiolase family
CDO23_RS23490	COG4948	Mandelate Racemase Muconate Lactonizing
CDO23_RS23515	COG1335	isochorismatase
CDO23_RS23520	COG0006	proline dipeptidase activity
CDO23_RS23530	COG5598	trimethylamine methyltransferase
CDO23_RS23580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO23_RS23585	COG0625	glutathione transferase activity
CDO23_RS23605	COG1802	Transcriptional regulator
CDO23_RS23615	COG3845	ABC transporter
CDO23_RS23620	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS23625	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS23695	COG0651	ATP synthesis coupled electron transport
CDO23_RS23705	COG0651	ATP synthesis coupled electron transport
CDO23_RS23715	COG0839	Belongs to the complex I subunit 6 family
CDO23_RS23720	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO23_RS23725	COG5001	Diguanylate cyclase
CDO23_RS23745	COG0840	transmembrane signaling receptor activity
CDO23_RS23750	COG2198	Histidine kinase
CDO23_RS23750	COG0643	Histidine kinase
CDO23_RS23785	COG0489	protein tyrosine kinase activity
CDO23_RS23810	COG3264	Mechanosensitive ion channel
CDO23_RS23810	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CDO23_RS23855	COG1672	PFAM Archaeal ATPase
CDO23_RS23855	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS23860	COG0723	plastoquinol--plastocyanin reductase activity
CDO23_RS23880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO23_RS23880	COG4651	solute:proton antiporter activity
CDO23_RS23890	COG1902	pentaerythritol trinitrate reductase activity
CDO23_RS23900	COG3328	transposase activity
CDO23_RS23920	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS23930	COG0583	DNA-binding transcription factor activity
CDO23_RS23965	COG0444	Belongs to the ABC transporter superfamily
CDO23_RS23970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS24040	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDO23_RS24045	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDO23_RS24050	COG0490	domain, Protein
CDO23_RS24050	COG0471	metal ion transport
CDO23_RS24090	COG3119	arylsulfatase activity
CDO23_RS24095	COG4191	Histidine kinase
CDO23_RS24170	COG2252	PERMEase
CDO23_RS24180	COG0583	DNA-binding transcription factor activity
CDO23_RS24190	COG1335	isochorismatase
CDO23_RS24200	COG1309	transcriptional regulator
CDO23_RS24210	COG3328	transposase activity
CDO23_RS24240	COG1484	DNA-dependent DNA replication
CDO23_RS24260	COG0583	DNA-binding transcription factor activity
CDO23_RS24285	COG1120	ATPase activity
CDO23_RS24290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO23_RS24295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO23_RS24320	COG1177	transmembrane transport
CDO23_RS24325	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO23_RS24330	COG3842	ATPase activity
CDO23_RS24340	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS24345	COG1802	Transcriptional regulator
CDO23_RS24355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO23_RS24405	COG1672	PFAM Archaeal ATPase
CDO23_RS24405	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS24475	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO23_RS24480	COG2814	Major facilitator Superfamily
CDO23_RS24490	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CDO23_RS24500	COG1335	isochorismatase
CDO23_RS24515	COG2207	Transcriptional regulator
CDO23_RS24560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO23_RS24575	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS24580	COG0473	3-isopropylmalate dehydrogenase activity
CDO23_RS24585	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS24590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS24600	COG0454	-acetyltransferase
CDO23_RS24620	COG0601	transmembrane transport
CDO23_RS24625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS24635	COG1522	sequence-specific DNA binding
CDO23_RS24650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO23_RS24660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO23_RS24670	COG1120	ATPase activity
CDO23_RS24700	COG0492	ferredoxin-NADP+ reductase activity
CDO23_RS24705	COG0492	ferredoxin-NADP+ reductase activity
CDO23_RS24710	COG0583	DNA-binding transcription factor activity
CDO23_RS24735	COG1404	Belongs to the peptidase S8 family
CDO23_RS24825	COG4584	PFAM Integrase catalytic
CDO23_RS24830	COG1484	DNA-dependent DNA replication
CDO23_RS24870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO23_RS24935	COG2814	Major facilitator Superfamily
CDO23_RS24950	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CDO23_RS24960	COG0583	DNA-binding transcription factor activity
CDO23_RS24990	COG0235	Class ii aldolase
CDO23_RS25000	COG0583	DNA-binding transcription factor activity
CDO23_RS25020	COG3609	addiction module antidote protein, CC2985 family
CDO23_RS25025	COG0402	S-adenosylhomocysteine deaminase activity
CDO23_RS25030	COG1957	nucleoside hydrolase
CDO23_RS25040	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS25045	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS25050	COG3845	ABC transporter
CDO23_RS25055	COG1744	ABC transporter substrate-binding protein PnrA-like
CDO23_RS25065	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CDO23_RS25070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO23_RS25110	COG3831	ATPase activity
CDO23_RS25170	COG3505	Type IV secretory pathway VirD4
CDO23_RS25175	COG0745	RESPONSE REGULATOR receiver
CDO23_RS25185	COG4974	Belongs to the 'phage' integrase family
CDO23_RS25260	COG3328	transposase activity
CDO23_RS25300	COG4638	Rieske (2fe-2S)
CDO23_RS25305	COG0583	DNA-binding transcription factor activity
CDO23_RS25310	COG0492	ferredoxin-NADP+ reductase activity
CDO23_RS25315	COG1484	DNA-dependent DNA replication
CDO23_RS25330	COG2226	methyltransferase
CDO23_RS25350	COG1115	amino acid carrier protein
CDO23_RS25370	COG1278	Cold shock
CDO23_RS25460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO23_RS25475	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO23_RS25490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO23_RS25505	COG1396	sequence-specific DNA binding
CDO23_RS25520	COG5001	Diguanylate cyclase
CDO23_RS25560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO23_RS25565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO23_RS25565	COG2010	Cytochrome c
CDO23_RS25570	COG2010	Cytochrome c
CDO23_RS25585	COG3842	ATPase activity
CDO23_RS25595	COG1840	ABC-type Fe3 transport system, periplasmic component
CDO23_RS25600	COG1609	Transcriptional regulator
CDO23_RS25605	COG1309	transcriptional regulator
CDO23_RS25620	COG1136	(ABC) transporter
CDO23_RS25625	COG0698	ribose 5-phosphate isomerase
CDO23_RS25630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS25640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS25645	COG2186	Transcriptional regulator
CDO23_RS25665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO23_RS25670	COG3842	ATPase activity
CDO23_RS25675	COG1177	transmembrane transport
CDO23_RS25680	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO23_RS25710	COG0604	alcohol dehydrogenase
CDO23_RS25735	COG2186	Transcriptional regulator
CDO23_RS25740	COG1850	ribulose-bisphosphate carboxylase activity
CDO23_RS25750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS25755	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO23_RS25760	COG2080	2 iron, 2 sulfur cluster binding
CDO23_RS25785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS25785	COG2010	Cytochrome c
CDO23_RS25790	COG2080	2 iron, 2 sulfur cluster binding
CDO23_RS25795	COG2010	Cytochrome c
CDO23_RS25795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS25805	COG0145	ligase activity
CDO23_RS25810	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CDO23_RS25815	COG4647	ligase activity
CDO23_RS25855	COG1653	transport
CDO23_RS25860	COG1175	transmembrane transport
CDO23_RS25865	COG0395	ABC-type sugar transport system, permease component
CDO23_RS25870	COG3842	ATPase activity
CDO23_RS25875	COG0625	glutathione transferase activity
CDO23_RS25880	COG1063	alcohol dehydrogenase
CDO23_RS25885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO23_RS25890	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS25895	COG1522	sequence-specific DNA binding
CDO23_RS25900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO23_RS25905	COG1126	abc transporter atp-binding protein
CDO23_RS25915	COG0765	amino acid transport
CDO23_RS25920	COG0765	amino acid transport
CDO23_RS25925	COG3473	Maleate cis-trans isomerase
CDO23_RS25930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO23_RS25935	COG2423	ornithine cyclodeaminase activity
CDO23_RS25940	COG0006	proline dipeptidase activity
CDO23_RS25945	COG3608	succinylglutamate desuccinylase aspartoacylase
CDO23_RS25960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS25970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS25975	COG1063	alcohol dehydrogenase
CDO23_RS25980	COG1312	Catalyzes the dehydration of D-mannonate
CDO23_RS25985	COG5001	Diguanylate cyclase
CDO23_RS25985	COG3300	MHYT domain
CDO23_RS26025	COG1309	transcriptional regulator
CDO23_RS26030	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS26080	COG1363	Peptidase, m42
CDO23_RS26085	COG4585	Histidine kinase
CDO23_RS26115	COG2192	nodulation
CDO23_RS26140	COG0747	negative chemotaxis
CDO23_RS26145	COG0601	transmembrane transport
CDO23_RS26155	COG4608	Belongs to the ABC transporter superfamily
CDO23_RS26160	COG2188	Transcriptional regulator
CDO23_RS26165	COG0367	asparagine synthase
CDO23_RS26185	COG1129	ABC transporter
CDO23_RS26190	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS26210	COG0235	Class ii aldolase
CDO23_RS26230	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS26235	COG0583	DNA-binding transcription factor activity
CDO23_RS26255	COG1070	Carbohydrate kinase
CDO23_RS26265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CDO23_RS26270	COG0667	Aldo Keto reductase
CDO23_RS26280	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS26285	COG1129	ABC transporter
CDO23_RS26305	COG1129	ABC transporter
CDO23_RS26315	COG2186	Transcriptional regulator
CDO23_RS26320	COG4948	Mandelate Racemase Muconate Lactonizing
CDO23_RS26325	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS26340	COG2201	protein-glutamate methylesterase activity
CDO23_RS26370	COG3706	GGDEF domain
CDO23_RS26380	COG1309	transcriptional regulator
CDO23_RS26400	COG3220	belongs to the UPF0276 family
CDO23_RS26445	COG1609	Transcriptional regulator
CDO23_RS26570	COG2832	Protein of unknown function (DUF454)
CDO23_RS26630	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO23_RS26660	COG1132	(ABC) transporter
CDO23_RS26675	COG1609	Transcriptional regulator
CDO23_RS26695	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO23_RS26715	COG0110	maltose O-acetyltransferase activity
CDO23_RS26765	COG0517	IMP dehydrogenase activity
CDO23_RS26765	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDO23_RS26835	COG1696	Membrane protein involved in D-alanine export
CDO23_RS26850	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS26850	COG3347	Dehydrogenase
CDO23_RS26865	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS26970	COG0601	transmembrane transport
CDO23_RS26975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS26985	COG2843	Capsule synthesis protein
CDO23_RS26990	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDO23_RS27005	COG1793	dna ligase
CDO23_RS27005	COG3285	dna ligase
CDO23_RS27025	COG4584	PFAM Integrase catalytic
CDO23_RS27030	COG1484	DNA-dependent DNA replication
CDO23_RS27055	COG1525	nuclease
CDO23_RS27105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO23_RS27130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDO23_RS27155	COG0165	Argininosuccinate lyase
CDO23_RS27165	COG1126	abc transporter atp-binding protein
CDO23_RS27175	COG2079	MmgE PrpD family protein
CDO23_RS27195	COG1414	Transcriptional regulator
CDO23_RS27210	COG0395	ABC-type sugar transport system, permease component
CDO23_RS27215	COG3842	ATPase activity
CDO23_RS27220	COG4948	Mandelate Racemase Muconate Lactonizing
CDO23_RS27225	COG3254	rhamnose metabolic process
CDO23_RS27240	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS27245	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO23_RS27250	COG4948	Mandelate Racemase Muconate Lactonizing
CDO23_RS27255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO23_RS27260	COG3707	response regulator
CDO23_RS27270	COG1396	sequence-specific DNA binding
CDO23_RS27275	COG3265	gluconokinase activity
CDO23_RS27285	COG1960	acyl-CoA dehydrogenase activity
CDO23_RS27290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO23_RS27325	COG0277	FAD linked oxidase domain protein
CDO23_RS27330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO23_RS27335	COG4208	sulfate ABC transporter
CDO23_RS27345	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDO23_RS27360	COG0765	amino acid transport
CDO23_RS27365	COG0765	amino acid transport
CDO23_RS27375	COG0251	oxidation-reduction process
CDO23_RS27385	COG3842	ATPase activity
CDO23_RS27390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO23_RS27415	COG1846	Transcriptional regulator
CDO23_RS27415	COG1940	carbohydrate kinase activity
CDO23_RS27420	COG0175	sulfate reduction
CDO23_RS27425	COG2895	sulfate adenylyltransferase (ATP) activity
CDO23_RS27425	COG0529	Catalyzes the synthesis of activated sulfate
CDO23_RS27445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS27475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO23_RS27505	COG0297	glycogen (starch) synthase activity
CDO23_RS27520	COG1596	polysaccharide export
CDO23_RS27525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDO23_RS27535	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDO23_RS27545	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS27550	COG0668	transmembrane transport
CDO23_RS27595	COG0747	negative chemotaxis
CDO23_RS27600	COG0601	transmembrane transport
CDO23_RS27605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS27630	COG1132	(ABC) transporter
CDO23_RS27635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO23_RS27635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO23_RS27645	COG1609	Transcriptional regulator
CDO23_RS27655	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO23_RS27660	COG1177	transmembrane transport
CDO23_RS27665	COG3842	ATPase activity
CDO23_RS27675	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO23_RS27680	COG1473	amidohydrolase
CDO23_RS27685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDO23_RS27690	COG2252	PERMEase
CDO23_RS27700	COG4266	Belongs to the allantoicase family
CDO23_RS27705	COG3195	allantoin biosynthetic process
CDO23_RS27705	COG3648	Uricase
CDO23_RS27710	COG2351	hydroxyisourate hydrolase activity
CDO23_RS27720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS27730	COG1733	regulation of RNA biosynthetic process
CDO23_RS27750	COG0402	S-adenosylhomocysteine deaminase activity
CDO23_RS27755	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO23_RS27760	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO23_RS27770	COG4953	penicillin-binding protein 1C
CDO23_RS27780	COG1349	DNA-binding transcription factor activity
CDO23_RS27785	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDO23_RS27790	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS27810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO23_RS27815	COG1732	Glycine betaine
CDO23_RS27820	COG1174	glycine betaine transport
CDO23_RS27825	COG1125	glycine betaine transport
CDO23_RS27830	COG1174	glycine betaine transport
CDO23_RS27835	COG0673	inositol 2-dehydrogenase activity
CDO23_RS27845	COG0395	ABC-type sugar transport system, permease component
CDO23_RS27855	COG3842	ATPase activity
CDO23_RS27880	COG0251	oxidation-reduction process
CDO23_RS27885	COG1737	Transcriptional regulator
CDO23_RS27910	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CDO23_RS27920	COG2986	histidine ammonia-lyase
CDO23_RS27925	COG1228	amidohydrolase
CDO23_RS27940	COG2814	Major facilitator Superfamily
CDO23_RS27945	COG0640	Transcriptional regulator
CDO23_RS27950	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CDO23_RS27955	COG3454	Phosphonate metabolism
CDO23_RS27960	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CDO23_RS27970	COG3639	organic phosphonate transmembrane transporter activity
CDO23_RS27975	COG3639	organic phosphonate transmembrane transporter activity
CDO23_RS27985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CDO23_RS28005	COG1960	acyl-CoA dehydrogenase activity
CDO23_RS28015	COG0326	Molecular chaperone. Has ATPase activity
CDO23_RS28020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDO23_RS28025	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS28030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO23_RS28040	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO23_RS28040	COG2755	lipolytic protein G-D-S-L family
CDO23_RS28045	COG1216	Glycosyl transferase, family 2
CDO23_RS28055	COG1132	(ABC) transporter
CDO23_RS28065	COG4166	transmembrane transport
CDO23_RS28070	COG0601	transmembrane transport
CDO23_RS28075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS28080	COG4172	Belongs to the ABC transporter superfamily
CDO23_RS28095	COG0346	lactoylglutathione lyase activity
CDO23_RS28110	COG0842	Transport permease protein
CDO23_RS28115	COG0842	Transport permease protein
CDO23_RS28120	COG1131	(ABC) transporter
CDO23_RS28125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO23_RS28135	COG2205	protein histidine kinase activity
CDO23_RS28140	COG0745	RESPONSE REGULATOR receiver
CDO23_RS28145	COG2194	sulfuric ester hydrolase activity
CDO23_RS28160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDO23_RS28165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO23_RS28195	COG0297	glycogen (starch) synthase activity
CDO23_RS28215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO23_RS28225	COG1846	Transcriptional regulator
CDO23_RS28265	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CDO23_RS28275	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDO23_RS28290	COG3237	CsbD-like
CDO23_RS28315	COG0628	permease
CDO23_RS28325	COG2080	2 iron, 2 sulfur cluster binding
CDO23_RS28330	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO23_RS28335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS28345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS28350	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS28355	COG1129	ABC transporter
CDO23_RS28360	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS28365	COG1609	Transcriptional regulator
CDO23_RS28375	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS28380	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CDO23_RS28385	COG2186	Transcriptional regulator
CDO23_RS28400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS28405	COG1904	glucuronate isomerase
CDO23_RS28410	COG0673	inositol 2-dehydrogenase activity
CDO23_RS28415	COG1295	ribonuclease BN
CDO23_RS28430	COG0583	DNA-binding transcription factor activity
CDO23_RS28445	COG2323	membrane
CDO23_RS28455	COG1295	ribonuclease BN
CDO23_RS28485	COG2010	Cytochrome c
CDO23_RS28485	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO23_RS28495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO23_RS28505	COG1609	Transcriptional regulator
CDO23_RS28510	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CDO23_RS28515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO23_RS28520	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS28525	COG1129	ABC transporter
CDO23_RS28530	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS28545	COG3485	protocatechuate 3,4-dioxygenase
CDO23_RS28560	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS28565	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CDO23_RS28570	COG2207	Transcriptional regulator
CDO23_RS28575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO23_RS28580	COG4521	taurine ABC transporter
CDO23_RS28585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CDO23_RS28590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO23_RS28605	COG0028	Belongs to the TPP enzyme family
CDO23_RS28610	COG2855	membrane
CDO23_RS28620	COG1349	DNA-binding transcription factor activity
CDO23_RS28640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO23_RS28650	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS28660	COG1840	ABC-type Fe3 transport system, periplasmic component
CDO23_RS28665	COG3842	ATPase activity
CDO23_RS28690	COG3275	phosphorelay sensor kinase activity
CDO23_RS28705	COG2897	thiosulfate sulfurtransferase activity
CDO23_RS28730	COG0475	glutathione-regulated potassium exporter activity
CDO23_RS28730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO23_RS28735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS28740	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO23_RS28745	COG2080	2 iron, 2 sulfur cluster binding
CDO23_RS28755	COG2205	protein histidine kinase activity
CDO23_RS28785	COG0459	protein refolding
CDO23_RS28790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO23_RS28795	COG5425	PFAM Usg family protein
CDO23_RS28815	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO23_RS28815	COG1902	pentaerythritol trinitrate reductase activity
CDO23_RS28835	COG2205	protein histidine kinase activity
CDO23_RS28845	COG0640	Transcriptional regulator
CDO23_RS28865	COG2217	Heavy metal translocating P-type atpase
CDO23_RS28870	COG0789	Transcriptional regulator
CDO23_RS28875	COG1238	metal cluster binding
CDO23_RS28880	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS28905	COG0189	ligase activity
CDO23_RS28910	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS28915	COG1129	ABC transporter
CDO23_RS28920	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS28925	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS28930	COG2186	Transcriptional regulator
CDO23_RS28945	COG1175	transmembrane transport
CDO23_RS28950	COG1653	transport
CDO23_RS28960	COG0673	inositol 2-dehydrogenase activity
CDO23_RS28965	COG1609	Transcriptional regulator
CDO23_RS28985	COG0395	ABC-type sugar transport system, permease component
CDO23_RS28990	COG1175	transmembrane transport
CDO23_RS28995	COG2182	Extracellular solute-binding protein
CDO23_RS29015	COG0750	zinc metalloprotease
CDO23_RS29025	COG0793	Belongs to the peptidase S41A family
CDO23_RS29025	COG3409	Peptidoglycan-binding domain 1 protein
CDO23_RS29030	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS29035	COG1129	ABC transporter
CDO23_RS29045	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CDO23_RS29045	COG2273	Hydrolase Family 16
CDO23_RS29050	COG2202	Pas domain
CDO23_RS29050	COG3920	Histidine kinase
CDO23_RS29055	COG0784	Response regulator, receiver
CDO23_RS29080	COG0602	queuosine metabolic process
CDO23_RS29085	COG0720	synthase
CDO23_RS29090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDO23_RS29095	COG5265	(ABC) transporter
CDO23_RS29100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDO23_RS29105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO23_RS29110	COG3307	-O-antigen
CDO23_RS29115	COG1596	polysaccharide export
CDO23_RS29120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDO23_RS29130	COG1215	transferase activity, transferring glycosyl groups
CDO23_RS29135	COG2327	Polysaccharide pyruvyl transferase
CDO23_RS29140	COG0463	Glycosyl transferase, family 2
CDO23_RS29145	COG2244	polysaccharide biosynthetic process
CDO23_RS29155	COG1525	nuclease
CDO23_RS29170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO23_RS29175	COG2273	Hydrolase Family 16
CDO23_RS29180	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS29185	COG1215	transferase activity, transferring glycosyl groups
CDO23_RS29190	COG1215	transferase activity, transferring glycosyl groups
CDO23_RS29195	COG1215	transferase activity, transferring glycosyl groups
CDO23_RS29200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO23_RS29205	COG3206	protein involved in exopolysaccharide biosynthesis
CDO23_RS29205	COG0489	protein tyrosine kinase activity
CDO23_RS29215	COG0351	phosphomethylpyrimidine kinase
CDO23_RS29230	COG0450	alkyl hydroperoxide reductase
CDO23_RS29245	COG1609	Transcriptional regulator
CDO23_RS29255	COG0395	ABC-type sugar transport system, permease component
CDO23_RS29260	COG1175	transmembrane transport
CDO23_RS29270	COG3842	ATPase activity
CDO23_RS29275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO23_RS29285	COG0765	amino acid transport
CDO23_RS29305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS29315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS29330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO23_RS29340	COG0243	molybdopterin cofactor binding
CDO23_RS29345	COG1648	precorrin-2 dehydrogenase activity
CDO23_RS29345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO23_RS29350	COG1051	belongs to the nudix hydrolase family
CDO23_RS29360	COG0330	HflC and HflK could
CDO23_RS29390	COG1959	2 iron, 2 sulfur cluster binding
CDO23_RS29395	COG1160	GTP binding
CDO23_RS29415	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CDO23_RS29420	COG0477	Major facilitator Superfamily
CDO23_RS29430	COG0024	Methionine aminopeptidase
CDO23_RS29465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDO23_RS29470	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS29485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS29495	COG0583	DNA-binding transcription factor activity
CDO23_RS29505	COG0402	S-adenosylhomocysteine deaminase activity
CDO23_RS29515	COG2390	Transcriptional regulator
CDO23_RS29520	COG1069	ribulokinase activity
CDO23_RS29525	COG1063	alcohol dehydrogenase
CDO23_RS29530	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS29535	COG1129	ABC transporter
CDO23_RS29540	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS29545	COG2140	Oxalate decarboxylase
CDO23_RS29590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO23_RS29600	COG4191	Histidine kinase
CDO23_RS29610	COG4566	intracellular signal transduction
CDO23_RS29615	COG0583	DNA-binding transcription factor activity
CDO23_RS29620	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS29625	COG2351	hydroxyisourate hydrolase activity
CDO23_RS29630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CDO23_RS29635	COG3195	allantoin biosynthetic process
CDO23_RS29635	COG3648	Uricase
CDO23_RS29655	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CDO23_RS29655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS29665	COG0513	Belongs to the DEAD box helicase family
CDO23_RS29675	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO23_RS29700	COG2308	Evidence 4 Homologs of previously reported genes of
CDO23_RS29710	COG1305	Transglutaminase-like
CDO23_RS29720	COG0129	dihydroxy-acid dehydratase activity
CDO23_RS29725	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS29735	COG4214	carbohydrate transport
CDO23_RS29745	COG4213	ABC transporter substrate-binding protein
CDO23_RS29770	COG0673	inositol 2-dehydrogenase activity
CDO23_RS29790	COG4213	ABC transporter substrate-binding protein
CDO23_RS29795	COG4214	carbohydrate transport
CDO23_RS29800	COG1129	ABC transporter
CDO23_RS29815	COG3547	Transposase (IS116 IS110 IS902 family)
CDO23_RS29820	COG3547	Transposase (IS116 IS110 IS902 family)
CDO23_RS29890	COG1335	isochorismatase
CDO23_RS29900	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDO23_RS29930	COG3189	MarR family transcriptional regulator
CDO23_RS29935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDO23_RS29950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDO23_RS29985	COG1129	ABC transporter
CDO23_RS29990	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS30020	COG1120	ATPase activity
CDO23_RS30025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO23_RS30035	COG2226	methyltransferase
CDO23_RS30045	COG0583	DNA-binding transcription factor activity
CDO23_RS30055	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS30060	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO23_RS30065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS30120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDO23_RS30125	COG1573	uracil-dna glycosylase
CDO23_RS30180	COG3842	ATPase activity
CDO23_RS30185	COG1653	transport
CDO23_RS30190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDO23_RS30190	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CDO23_RS30195	COG1486	melibiose metabolic process
CDO23_RS30200	COG2188	Transcriptional regulator
CDO23_RS30205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO23_RS30210	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CDO23_RS30250	COG0300	oxidoreductase activity
CDO23_RS30270	COG3344	reverse transcriptase
CDO23_RS30290	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CDO23_RS30330	COG0477	Major facilitator Superfamily
CDO23_RS30340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO23_RS30345	COG1845	cytochrome c oxidase, subunit III
CDO23_RS30350	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDO23_RS30355	COG3385	transposase activity
CDO23_RS30360	COG3346	SURF1 family
CDO23_RS30395	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CDO23_RS30425	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS30430	COG3415	Transposase
CDO23_RS30430	COG2801	Transposase and inactivated derivatives
CDO23_RS30450	COG0297	glycogen (starch) synthase activity
CDO23_RS30470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO23_RS30490	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO23_RS30500	COG1376	ErfK ybiS ycfS ynhG family protein
CDO23_RS30500	COG1388	LysM domain
CDO23_RS30515	COG4585	Histidine kinase
CDO23_RS30520	COG2197	response regulator
CDO23_RS30530	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDO23_RS30535	COG2894	cell division
CDO23_RS30540	COG0850	regulation of cytokinetic process
CDO23_RS30550	COG0656	L-ascorbic acid biosynthetic process
CDO23_RS30560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDO23_RS30565	COG0318	PFAM AMP-dependent synthetase and ligase
CDO23_RS30575	COG0367	asparagine synthase
CDO23_RS30600	COG0667	Aldo Keto reductase
CDO23_RS30610	COG0395	ABC-type sugar transport system, permease component
CDO23_RS30615	COG1175	transmembrane transport
CDO23_RS30625	COG3842	ATPase activity
CDO23_RS30635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS30645	COG0235	Class ii aldolase
CDO23_RS30650	COG1609	Transcriptional regulator
CDO23_RS30655	COG2084	Dehydrogenase
CDO23_RS30660	COG3622	Belongs to the hyi family
CDO23_RS30665	COG3395	kinase activity
CDO23_RS30690	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS30695	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS30720	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CDO23_RS30730	COG2084	Dehydrogenase
CDO23_RS30735	COG3622	Belongs to the hyi family
CDO23_RS30740	COG3960	tartronate-semialdehyde synthase activity
CDO23_RS30745	COG1414	Transcriptional regulator
CDO23_RS30750	COG0583	DNA-binding transcription factor activity
CDO23_RS30755	COG3257	ureidoglycine aminohydrolase activity
CDO23_RS30765	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDO23_RS30795	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS30800	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS30820	COG4187	Peptidase family M20/M25/M40
CDO23_RS30855	COG0297	glycogen (starch) synthase activity
CDO23_RS30875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO23_RS30880	COG2094	Belongs to the DNA glycosylase MPG family
CDO23_RS30885	COG2084	Dehydrogenase
CDO23_RS30900	COG1129	ABC transporter
CDO23_RS30905	COG4211	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS30920	COG1609	Transcriptional regulator
CDO23_RS30925	COG1129	ABC transporter
CDO23_RS30930	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS30990	COG0174	glutamine synthetase
CDO23_RS31000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO23_RS31005	COG1215	transferase activity, transferring glycosyl groups
CDO23_RS31010	COG0246	Mannitol dehydrogenase
CDO23_RS31015	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS31025	COG1024	Enoyl-CoA hydratase
CDO23_RS31030	COG1960	acyl-CoA dehydrogenase activity
CDO23_RS31035	COG1396	sequence-specific DNA binding
CDO23_RS31035	COG3800	Transcriptional regulator
CDO23_RS31040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO23_RS31045	COG4770	biotin carboxylase activity
CDO23_RS31050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDO23_RS31050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDO23_RS31055	COG2188	Transcriptional regulator
CDO23_RS31060	COG3624	Phosphonate C-P lyase system protein PhnG
CDO23_RS31065	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CDO23_RS31070	COG3626	phosphonate metabolism
CDO23_RS31075	COG3627	carbon phosphorus lyase activity
CDO23_RS31080	COG4107	phosphonate C-P lyase system protein PhnK
CDO23_RS31085	COG4778	phosphonate C-P lyase system protein PhnL
CDO23_RS31095	COG2376	Dihydroxyacetone kinase
CDO23_RS31120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO23_RS31125	COG1802	Transcriptional regulator
CDO23_RS31155	COG0411	ABC transporter
CDO23_RS31170	COG0683	leucine binding
CDO23_RS31185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO23_RS31190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO23_RS31210	COG3485	protocatechuate 3,4-dioxygenase
CDO23_RS31215	COG3485	protocatechuate 3,4-dioxygenase
CDO23_RS31220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO23_RS31225	COG2267	carboxylic ester hydrolase activity
CDO23_RS31230	COG0583	DNA-binding transcription factor activity
CDO23_RS31250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO23_RS31260	COG1414	Transcriptional regulator
CDO23_RS31265	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDO23_RS31270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDO23_RS31275	COG0183	Belongs to the thiolase family
CDO23_RS31280	COG1254	Belongs to the acylphosphatase family
CDO23_RS31285	COG1595	DNA-templated transcription, initiation
CDO23_RS31315	COG1192	Involved in chromosome partitioning
CDO23_RS31320	COG1475	DNA binding
CDO23_RS31335	COG0411	ABC transporter
CDO23_RS31380	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS31380	COG1672	PFAM Archaeal ATPase
CDO23_RS31385	COG2198	Histidine kinase
CDO23_RS31385	COG5002	protein histidine kinase activity
CDO23_RS31385	COG0784	Response regulator, receiver
CDO23_RS31395	COG1301	dicarboxylic acid transport
CDO23_RS31400	COG4191	Histidine kinase
CDO23_RS31405	COG2204	response regulator
CDO23_RS31415	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDO23_RS31430	COG2022	thiamine diphosphate biosynthetic process
CDO23_RS31440	COG2814	Major facilitator Superfamily
CDO23_RS31455	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDO23_RS31475	COG0395	ABC-type sugar transport system, permease component
CDO23_RS31480	COG1175	transmembrane transport
CDO23_RS31490	COG1609	Transcriptional regulator
CDO23_RS31500	COG0019	diaminopimelate decarboxylase activity
CDO23_RS31505	COG1024	Enoyl-CoA hydratase
CDO23_RS31505	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO23_RS31510	COG1024	Enoyl-CoA hydratase
CDO23_RS31515	COG1607	acyl-coa hydrolase
CDO23_RS31520	COG2030	dehydratase
CDO23_RS31520	COG1012	belongs to the aldehyde dehydrogenase family
CDO23_RS31525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDO23_RS31530	COG2151	metal-sulfur cluster biosynthetic enzyme
CDO23_RS31535	COG3396	Phenylacetate-CoA oxygenase
CDO23_RS31540	COG3460	Phenylacetate-CoA oxygenase
CDO23_RS31545	COG3396	Phenylacetate-CoA oxygenase
CDO23_RS31560	COG1486	melibiose metabolic process
CDO23_RS31565	COG4172	Belongs to the ABC transporter superfamily
CDO23_RS31570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS31575	COG0601	transmembrane transport
CDO23_RS31580	COG0747	negative chemotaxis
CDO23_RS31585	COG1486	melibiose metabolic process
CDO23_RS31635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDO23_RS31645	COG0625	glutathione transferase activity
CDO23_RS31655	COG0753	catalase activity
CDO23_RS31660	COG1793	dna ligase
CDO23_RS31665	COG0583	DNA-binding transcription factor activity
CDO23_RS31690	COG1609	Transcriptional regulator
CDO23_RS31695	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS31700	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS31705	COG1129	ABC transporter
CDO23_RS31720	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO23_RS31725	COG0022	dehydrogenase e1 component
CDO23_RS31730	COG1522	sequence-specific DNA binding
CDO23_RS31785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO23_RS31800	COG1309	transcriptional regulator
CDO23_RS31805	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO23_RS31810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS31815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS31820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDO23_RS31840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO23_RS31845	COG0697	spore germination
CDO23_RS31865	COG1414	Transcriptional regulator
CDO23_RS31870	COG1475	DNA binding
CDO23_RS31875	COG1192	Involved in chromosome partitioning
CDO23_RS31885	COG2188	Transcriptional regulator
CDO23_RS31890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDO23_RS31910	COG2358	TRAP transporter, solute receptor (TAXI family
CDO23_RS31930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO23_RS31935	COG1120	ATPase activity
CDO23_RS31960	COG3609	addiction module antidote protein, CC2985 family
CDO23_RS31985	COG3360	Dodecin
CDO23_RS31990	COG1115	amino acid carrier protein
CDO23_RS31995	COG0659	secondary active sulfate transmembrane transporter activity
CDO23_RS32005	COG2814	Major facilitator Superfamily
CDO23_RS32015	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS32030	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS32035	COG4585	Histidine kinase
CDO23_RS32040	COG2197	response regulator
CDO23_RS32115	COG3685	Protein conserved in bacteria
CDO23_RS32125	COG0392	lysyltransferase activity
CDO23_RS32135	COG0028	Belongs to the TPP enzyme family
CDO23_RS32160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO23_RS32165	COG0579	oxidoreductase
CDO23_RS32170	COG3284	Transcriptional regulator
CDO23_RS32185	COG1802	Transcriptional regulator
CDO23_RS32200	COG0747	negative chemotaxis
CDO23_RS32205	COG0601	transmembrane transport
CDO23_RS32210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS32225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO23_RS32230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO23_RS32245	COG0438	transferase activity, transferring glycosyl groups
CDO23_RS32280	COG0626	cystathionine gamma-synthase activity
CDO23_RS32285	COG0583	DNA-binding transcription factor activity
CDO23_RS32290	COG3845	ABC transporter
CDO23_RS32295	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS32300	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS32320	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO23_RS32330	COG2080	2 iron, 2 sulfur cluster binding
CDO23_RS32330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS32335	COG0523	cobalamin synthesis protein
CDO23_RS32340	COG2233	PERMEase
CDO23_RS32345	COG0163	prenyltransferase activity
CDO23_RS32370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO23_RS32380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO23_RS32385	COG0601	transmembrane transport
CDO23_RS32390	COG0747	negative chemotaxis
CDO23_RS32400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO23_RS32405	COG1454	alcohol dehydrogenase
CDO23_RS32415	COG3395	kinase activity
CDO23_RS32440	COG1609	Transcriptional regulator
CDO23_RS32445	COG1178	ABC-type Fe3 transport system permease component
CDO23_RS32450	COG3842	ATPase activity
CDO23_RS32525	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDO23_RS32530	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDO23_RS32590	COG1116	anion transmembrane transporter activity
CDO23_RS32595	COG1131	(ABC) transporter
CDO23_RS32600	COG0842	Transport permease protein
CDO23_RS32605	COG3791	Glutathione-dependent formaldehyde-activating
CDO23_RS32630	COG4451	ribulose bisphosphate carboxylase, small
CDO23_RS32635	COG1850	ribulose-bisphosphate carboxylase activity
CDO23_RS32640	COG0191	fructose-bisphosphate aldolase activity
CDO23_RS32645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO23_RS32650	COG3954	Phosphoribulokinase
CDO23_RS32655	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CDO23_RS32660	COG0583	DNA-binding transcription factor activity
CDO23_RS32670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDO23_RS32675	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CDO23_RS32680	COG0535	radical SAM domain protein
CDO23_RS32685	COG0535	radical SAM domain protein
CDO23_RS32695	COG1028	Short-chain dehydrogenase reductase Sdr
CDO23_RS32700	COG0583	DNA-binding transcription factor activity
CDO23_RS32710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO23_RS32710	COG0785	Cytochrome C biogenesis protein
CDO23_RS32715	COG0300	oxidoreductase activity
CDO23_RS32765	COG0596	Alpha beta hydrolase
CDO23_RS32770	COG0596	Alpha beta hydrolase
CDO23_RS32815	COG1609	Transcriptional regulator
CDO23_RS32820	COG2182	Extracellular solute-binding protein
CDO23_RS32825	COG1175	transmembrane transport
CDO23_RS32830	COG0395	ABC-type sugar transport system, permease component
CDO23_RS32840	COG3842	ATPase activity
CDO23_RS32860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS32885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO23_RS32900	COG0673	inositol 2-dehydrogenase activity
CDO23_RS32910	COG1260	myo-inositol-1-phosphate synthase
CDO23_RS32950	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO23_RS32960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO23_RS32970	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CDO23_RS32990	COG0765	amino acid transport
CDO23_RS33000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO23_RS33005	COG3938	Belongs to the proline racemase family
CDO23_RS33015	COG3938	Belongs to the proline racemase family
CDO23_RS33020	COG1765	OsmC-like protein
CDO23_RS33025	COG2814	Major facilitator Superfamily
CDO23_RS33045	COG3246	L-lysine catabolic process to acetate
CDO23_RS33055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO23_RS33070	COG2072	flavoprotein involved in K transport
CDO23_RS33075	COG3842	ATPase activity
CDO23_RS33080	COG1177	transmembrane transport
CDO23_RS33110	COG0402	S-adenosylhomocysteine deaminase activity
CDO23_RS33115	COG2233	PERMEase
CDO23_RS33120	COG1609	Transcriptional regulator
CDO23_RS33130	COG2358	TRAP transporter, solute receptor (TAXI family
CDO23_RS33145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS33150	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO23_RS33150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS33155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO23_RS33160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO23_RS33165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO23_RS33175	COG2133	pyrroloquinoline quinone binding
CDO23_RS33195	COG2376	Dihydroxyacetone kinase
CDO23_RS33200	COG1461	Dihydroxyacetone kinase
CDO23_RS33205	COG2376	Dihydroxyacetone kinase
CDO23_RS33215	COG1879	ABC-type sugar transport system periplasmic component
CDO23_RS33220	COG1129	ABC transporter
CDO23_RS33225	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS33240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO23_RS33260	COG1609	Transcriptional regulator
CDO23_RS33265	COG1653	transport
CDO23_RS33280	COG3842	ATPase activity
CDO23_RS33290	COG0673	inositol 2-dehydrogenase activity
CDO23_RS33335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO23_RS33350	COG1309	transcriptional regulator
CDO23_RS33380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO23_RS33380	COG2010	Cytochrome c
CDO23_RS33390	COG2207	Transcriptional regulator
CDO23_RS33410	COG0287	Prephenate dehydrogenase
CDO23_RS33430	COG1129	ABC transporter
CDO23_RS33435	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO23_RS33440	COG0673	inositol 2-dehydrogenase activity
CDO23_RS33455	COG0784	Response regulator, receiver
CDO23_RS33455	COG2205	protein histidine kinase activity