locus-tag	class	description
CDO28_RS00015	COG1368	sulfuric ester hydrolase activity
CDO28_RS00025	COG0823	Involved in the tonB-independent uptake of proteins
CDO28_RS00045	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS00050	COG0778	Nitroreductase
CDO28_RS00065	COG2197	response regulator
CDO28_RS00070	COG0281	malic enzyme
CDO28_RS00070	COG0280	phosphate acetyltransferase
CDO28_RS00085	COG2814	Major facilitator Superfamily
CDO28_RS00090	COG4948	Mandelate Racemase Muconate Lactonizing
CDO28_RS00095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDO28_RS00100	COG1127	ABC transporter
CDO28_RS00110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDO28_RS00110	COG3218	ABC-type transport auxiliary lipoprotein component
CDO28_RS00115	COG3657	addiction module killer protein
CDO28_RS00125	COG0408	coproporphyrinogen oxidase activity
CDO28_RS00140	COG0789	Transcriptional regulator
CDO28_RS00145	COG0431	NADPH-dependent FMN reductase
CDO28_RS00150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDO28_RS00155	COG1132	(ABC) transporter
CDO28_RS00160	COG1132	(ABC) transporter
CDO28_RS00175	COG2857	Cytochrome c1
CDO28_RS00175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CDO28_RS00195	COG0633	Ferredoxin
CDO28_RS00210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDO28_RS00215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDO28_RS00230	COG3768	UPF0283 membrane protein
CDO28_RS00235	COG3106	COG3106 Predicted ATPase
CDO28_RS00260	COG2313	pseudouridylate synthase activity
CDO28_RS00265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO28_RS00270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDO28_RS00275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDO28_RS00280	COG0659	secondary active sulfate transmembrane transporter activity
CDO28_RS00305	COG0538	isocitrate dehydrogenase activity
CDO28_RS00315	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CDO28_RS00320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDO28_RS00330	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDO28_RS00335	COG2066	Belongs to the glutaminase family
CDO28_RS00340	COG0037	tRNA processing
CDO28_RS00345	COG0483	inositol monophosphate 1-phosphatase activity
CDO28_RS00350	COG2814	Major facilitator Superfamily
CDO28_RS00355	COG2814	Major facilitator Superfamily
CDO28_RS00375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO28_RS00385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO28_RS00400	COG0047	phosphoribosylformylglycinamidine synthase activity
CDO28_RS00405	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO28_RS00410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDO28_RS00445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO28_RS00450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDO28_RS00480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDO28_RS00500	COG3191	aminopeptidase activity
CDO28_RS00510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDO28_RS00515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO28_RS00530	COG3608	succinylglutamate desuccinylase aspartoacylase
CDO28_RS00530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDO28_RS00535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDO28_RS00550	COG0513	Belongs to the DEAD box helicase family
CDO28_RS00555	COG0739	heme binding
CDO28_RS00560	COG2833	Protein of unknown function (DUF455)
CDO28_RS00565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDO28_RS00575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDO28_RS00580	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDO28_RS00590	COG2945	thiolester hydrolase activity
CDO28_RS00600	COG0719	Fe-S assembly protein
CDO28_RS00605	COG0396	ATPase activity
CDO28_RS00610	COG0719	Fe-S assembly protein
CDO28_RS00615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDO28_RS00620	COG2151	metal-sulfur cluster biosynthetic enzyme
CDO28_RS00625	COG0316	Belongs to the HesB IscA family
CDO28_RS00630	COG3385	transposase activity
CDO28_RS00640	COG2003	Belongs to the UPF0758 family
CDO28_RS00645	COG0024	Methionine aminopeptidase
CDO28_RS00650	COG1489	DNA binding
CDO28_RS00655	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDO28_RS00665	COG0436	Aminotransferase
CDO28_RS00710	COG1278	Cold shock
CDO28_RS00755	COG0583	DNA-binding transcription factor activity
CDO28_RS00795	COG1522	sequence-specific DNA binding
CDO28_RS00820	COG0583	DNA-binding transcription factor activity
CDO28_RS00825	COG2084	Dehydrogenase
CDO28_RS00830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS00835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS00840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS00845	COG3959	Transketolase, thiamine diphosphate binding domain
CDO28_RS00850	COG3958	Transketolase
CDO28_RS00855	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS00870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS00875	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS00885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO28_RS00895	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS00975	COG0785	Cytochrome C biogenesis protein
CDO28_RS00980	COG0679	Auxin Efflux Carrier
CDO28_RS00985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO28_RS00995	COG1183	phosphatidylcholine synthase activity
CDO28_RS01005	COG3845	ABC transporter
CDO28_RS01010	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS01015	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS01025	COG2186	Transcriptional regulator
CDO28_RS01030	COG1253	flavin adenine dinucleotide binding
CDO28_RS01040	COG0303	'Molybdopterin
CDO28_RS01045	COG0315	cyclic pyranopterin monophosphate synthase activity
CDO28_RS01050	COG0134	indole-3-glycerol-phosphate synthase activity
CDO28_RS01055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDO28_RS01060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO28_RS01070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDO28_RS01075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO28_RS01080	COG3153	acetyltransferase
CDO28_RS01090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDO28_RS01095	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDO28_RS01100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDO28_RS01135	COG3119	arylsulfatase activity
CDO28_RS01165	COG0174	glutamine synthetase
CDO28_RS01170	COG0347	Belongs to the P(II) protein family
CDO28_RS01175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDO28_RS01175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDO28_RS01180	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CDO28_RS01185	COG1546	Belongs to the CinA family
CDO28_RS01185	COG1058	Belongs to the CinA family
CDO28_RS01190	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDO28_RS01215	COG3795	YCII-related domain
CDO28_RS01330	COG3750	Belongs to the UPF0335 family
CDO28_RS01455	COG1783	phage Terminase large subunit
CDO28_RS01620	COG3179	chitinase
CDO28_RS01690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDO28_RS01695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO28_RS01705	COG0737	Belongs to the 5'-nucleotidase family
CDO28_RS01710	COG1522	sequence-specific DNA binding
CDO28_RS01715	COG0686	Belongs to the AlaDH PNT family
CDO28_RS01730	COG2897	thiosulfate sulfurtransferase activity
CDO28_RS01735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDO28_RS01745	COG4221	oxidoreductase activity
CDO28_RS01765	COG2076	Multidrug Resistance protein
CDO28_RS01850	COG3750	Belongs to the UPF0335 family
CDO28_RS01900	COG1030	water channel activity
CDO28_RS02085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDO28_RS02125	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDO28_RS02135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDO28_RS02150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO28_RS02155	COG0084	hydrolase, TatD family'
CDO28_RS02165	COG2801	Transposase and inactivated derivatives
CDO28_RS02180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDO28_RS02210	COG1376	ErfK ybiS ycfS ynhG family protein
CDO28_RS02210	COG1388	LysM domain
CDO28_RS02235	COG0300	oxidoreductase activity
CDO28_RS02245	COG0343	queuine tRNA-ribosyltransferase activity
CDO28_RS02250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDO28_RS02265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDO28_RS02280	COG0534	Mate efflux family protein
CDO28_RS02290	COG2321	neutral zinc metallopeptidase
CDO28_RS02300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDO28_RS02315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO28_RS02320	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS02325	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS02330	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS02335	COG0463	Glycosyl transferase, family 2
CDO28_RS02340	COG1522	sequence-specific DNA binding
CDO28_RS02345	COG0492	ferredoxin-NADP+ reductase activity
CDO28_RS02350	COG0583	DNA-binding transcription factor activity
CDO28_RS02360	COG1902	pentaerythritol trinitrate reductase activity
CDO28_RS02390	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDO28_RS02395	COG2095	MarC family integral membrane protein
CDO28_RS02400	COG0629	single-stranded DNA binding
CDO28_RS02405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDO28_RS02415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDO28_RS02430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDO28_RS02545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDO28_RS02615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO28_RS02620	COG0509	glycine decarboxylation via glycine cleavage system
CDO28_RS02625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDO28_RS02625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDO28_RS02630	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDO28_RS02650	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CDO28_RS02675	COG1862	Preprotein translocase
CDO28_RS02695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO28_RS02700	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CDO28_RS02705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDO28_RS02710	COG0805	protein transport
CDO28_RS02715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO28_RS02720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO28_RS02725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO28_RS02730	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDO28_RS02735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDO28_RS02740	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO28_RS02750	COG0018	arginyl-trna synthetase
CDO28_RS02755	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CDO28_RS02765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO28_RS02775	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CDO28_RS02785	COG0525	valine-tRNA ligase activity
CDO28_RS02800	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO28_RS02805	COG0848	biopolymer transport protein
CDO28_RS02820	COG0372	Belongs to the citrate synthase family
CDO28_RS02835	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO28_RS02845	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO28_RS02850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO28_RS02855	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDO28_RS02865	COG0750	zinc metalloprotease
CDO28_RS02875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDO28_RS02880	COG0233	cytoplasmic translational termination
CDO28_RS02885	COG0528	UMP kinase activity
CDO28_RS02890	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDO28_RS02895	COG0052	Belongs to the universal ribosomal protein uS2 family
CDO28_RS02925	COG0537	adenosine 5'-monophosphoramidase activity
CDO28_RS02945	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDO28_RS02960	COG1045	serine acetyltransferase
CDO28_RS02965	COG0596	Alpha beta hydrolase
CDO28_RS02980	COG0626	cystathionine gamma-synthase activity
CDO28_RS02985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO28_RS02990	COG4597	amino acid ABC transporter
CDO28_RS02995	COG0765	amino acid transport
CDO28_RS03000	COG1126	abc transporter atp-binding protein
CDO28_RS03020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO28_RS03030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO28_RS03030	COG1648	precorrin-2 dehydrogenase activity
CDO28_RS03040	COG3956	TIGRFAM MazG family protein
CDO28_RS03050	COG3415	Transposase
CDO28_RS03050	COG2801	Transposase and inactivated derivatives
CDO28_RS03060	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDO28_RS03065	COG1923	regulation of RNA biosynthetic process
CDO28_RS03070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO28_RS03075	COG0569	domain protein
CDO28_RS03080	COG2204	response regulator
CDO28_RS03085	COG5000	phosphorelay sensor kinase activity
CDO28_RS03090	COG2204	response regulator
CDO28_RS03095	COG3852	Histidine kinase
CDO28_RS03105	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDO28_RS03105	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDO28_RS03110	COG1546	Belongs to the CinA family
CDO28_RS03110	COG1058	Belongs to the CinA family
CDO28_RS03115	COG2867	negative regulation of translational initiation
CDO28_RS03125	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDO28_RS03135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO28_RS03150	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO28_RS03155	COG0022	dehydrogenase e1 component
CDO28_RS03155	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO28_RS03160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDO28_RS03170	COG0148	phosphopyruvate hydratase activity
CDO28_RS03175	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CDO28_RS03185	COG0504	CTP synthase activity
CDO28_RS03190	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDO28_RS03195	COG0149	triose-phosphate isomerase activity
CDO28_RS03220	COG0187	DNA topoisomerase II activity
CDO28_RS03260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDO28_RS03275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDO28_RS03285	COG0302	gtp cyclohydrolase
CDO28_RS03290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDO28_RS03300	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO28_RS03310	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CDO28_RS03360	COG1760	l-serine dehydratase
CDO28_RS03385	COG2239	Acts as a magnesium transporter
CDO28_RS03390	COG0242	peptide deformylase activity
CDO28_RS03405	COG2719	SpoVR family
CDO28_RS03410	COG2718	Belongs to the UPF0229 family
CDO28_RS03415	COG2766	serine protein kinase
CDO28_RS03425	COG0321	lipoyl(octanoyl) transferase activity
CDO28_RS03435	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDO28_RS03440	COG1671	Belongs to the UPF0178 family
CDO28_RS03450	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDO28_RS03455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDO28_RS03460	COG0564	pseudouridine synthase activity
CDO28_RS03465	COG0546	phosphoglycolate phosphatase activity
CDO28_RS03480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDO28_RS03485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO28_RS03490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO28_RS03495	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CDO28_RS03505	COG0203	ribosomal protein L17
CDO28_RS03510	COG0202	RNA polymerase activity
CDO28_RS03515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDO28_RS03520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDO28_RS03525	COG0563	adenylate kinase activity
CDO28_RS03535	COG0200	Binds to the 23S rRNA
CDO28_RS03540	COG1841	ribosomal large subunit assembly
CDO28_RS03545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDO28_RS03550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDO28_RS03555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDO28_RS03560	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDO28_RS03565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDO28_RS03570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDO28_RS03575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDO28_RS03580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDO28_RS03585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDO28_RS03590	COG0255	Belongs to the universal ribosomal protein uL29 family
CDO28_RS03595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDO28_RS03600	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDO28_RS03605	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDO28_RS03610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDO28_RS03615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDO28_RS03620	COG0089	rRNA binding
CDO28_RS03625	COG0088	Forms part of the polypeptide exit tunnel
CDO28_RS03630	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDO28_RS03635	COG0051	transcription antitermination factor activity, RNA binding
CDO28_RS03640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDO28_RS03645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDO28_RS03650	COG0049	tRNA binding
CDO28_RS03655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDO28_RS03665	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDO28_RS03670	COG0085	RNA polymerase activity
CDO28_RS03675	COG0222	ribosome binding
CDO28_RS03680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDO28_RS03685	COG0081	regulation of translation
CDO28_RS03690	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDO28_RS03710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS03720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDO28_RS03735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO28_RS03745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDO28_RS03765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDO28_RS03790	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO28_RS03795	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO28_RS03805	COG1530	ribonuclease E activity
CDO28_RS03830	COG0436	Aminotransferase
CDO28_RS03845	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDO28_RS03850	COG0511	ligase activity, forming carbon-carbon bonds
CDO28_RS03855	COG0439	Biotin carboxylase
CDO28_RS03860	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDO28_RS03880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDO28_RS03885	COG3811	Belongs to the UPF0386 family
CDO28_RS03890	COG0154	amidase activity
CDO28_RS03895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDO28_RS03900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDO28_RS03905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDO28_RS03925	COG1960	acyl-CoA dehydrogenase activity
CDO28_RS03930	COG0540	Belongs to the ATCase OTCase family
CDO28_RS03935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDO28_RS03940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDO28_RS03945	COG0758	DNA mediated transformation
CDO28_RS03950	COG1754	DNA topoisomerase type I activity
CDO28_RS03950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDO28_RS03955	COG0557	exoribonuclease II activity
CDO28_RS03975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDO28_RS03985	COG0784	Response regulator, receiver
CDO28_RS03995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO28_RS04010	COG1136	(ABC) transporter
CDO28_RS04020	COG0442	prolyl-tRNA aminoacylation
CDO28_RS04045	COG0346	lactoylglutathione lyase activity
CDO28_RS04060	COG1007	ATP synthesis coupled electron transport
CDO28_RS04075	COG0713	ATP synthesis coupled electron transport
CDO28_RS04085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO28_RS04090	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CDO28_RS04100	COG3743	rRNA binding
CDO28_RS04100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDO28_RS04105	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDO28_RS04110	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CDO28_RS04120	COG0649	NAD binding
CDO28_RS04125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO28_RS04130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO28_RS04135	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDO28_RS04165	COG4717	serine-type aminopeptidase activity
CDO28_RS04170	COG0420	3'-5' exonuclease activity
CDO28_RS04190	COG0776	regulation of translation
CDO28_RS04195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO28_RS04200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDO28_RS04205	COG0740	serine-type endopeptidase activity
CDO28_RS04210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO28_RS04220	COG2124	cytochrome p450
CDO28_RS04240	COG1832	CoA-binding protein
CDO28_RS04250	COG1024	Enoyl-CoA hydratase
CDO28_RS04265	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDO28_RS04270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDO28_RS04275	COG0010	Belongs to the arginase family
CDO28_RS04280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDO28_RS04285	COG1612	heme a metabolic process
CDO28_RS04300	COG0110	maltose O-acetyltransferase activity
CDO28_RS04320	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS04335	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS04370	COG0776	regulation of translation
CDO28_RS04375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO28_RS04380	COG0416	fatty acid biosynthetic process
CDO28_RS04400	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CDO28_RS04405	COG2814	Major facilitator Superfamily
CDO28_RS04410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO28_RS04415	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDO28_RS04425	COG0519	Catalyzes the synthesis of GMP from XMP
CDO28_RS04440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO28_RS04440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO28_RS04445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDO28_RS04450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDO28_RS04455	COG2989	Protein conserved in bacteria
CDO28_RS04470	COG0113	porphobilinogen synthase activity
CDO28_RS04480	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CDO28_RS04495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDO28_RS04510	COG0459	protein refolding
CDO28_RS04520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDO28_RS04535	COG2132	Multicopper oxidase
CDO28_RS04540	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CDO28_RS04545	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO28_RS04555	COG0248	Ppx GppA phosphatase
CDO28_RS04560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CDO28_RS04570	COG0628	permease
CDO28_RS04575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDO28_RS04580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDO28_RS04595	COG0494	nUDIX hydrolase
CDO28_RS04600	COG0243	molybdopterin cofactor binding
CDO28_RS04605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDO28_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS04635	COG0322	excinuclease ABC activity
CDO28_RS04650	COG0314	molybdopterin synthase activity
CDO28_RS04675	COG0105	UTP biosynthetic process
CDO28_RS04690	COG0318	PFAM AMP-dependent synthetase and ligase
CDO28_RS04700	COG0488	(ABC) transporter
CDO28_RS04725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO28_RS04755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO28_RS04760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDO28_RS04770	COG0194	GDP metabolic process
CDO28_RS04775	COG1561	YicC-like family, N-terminal region
CDO28_RS04780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDO28_RS04785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO28_RS04790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO28_RS04800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDO28_RS04805	COG0667	Aldo Keto reductase
CDO28_RS04815	COG0360	Binds together with S18 to 16S ribosomal RNA
CDO28_RS04820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDO28_RS04830	COG0359	binds to the 23S rRNA
CDO28_RS04850	COG0305	Participates in initiation and elongation during chromosome replication
CDO28_RS04870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDO28_RS04885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDO28_RS04890	COG4221	oxidoreductase activity
CDO28_RS04895	COG1183	phosphatidylcholine synthase activity
CDO28_RS04900	COG0688	phosphatidylethanolamine metabolic process
CDO28_RS04905	COG5265	(ABC) transporter
CDO28_RS04920	COG2962	Rard protein
CDO28_RS04925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDO28_RS04950	COG0215	cysteine-tRNA ligase activity
CDO28_RS04970	COG1051	belongs to the nudix hydrolase family
CDO28_RS04995	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CDO28_RS05020	COG2274	protein secretion by the type I secretion system
CDO28_RS05025	COG2032	superoxide dismutase activity
CDO28_RS05035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CDO28_RS05040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDO28_RS05055	COG1418	mRNA catabolic process
CDO28_RS05070	COG1381	Involved in DNA repair and RecF pathway recombination
CDO28_RS05075	COG1376	ErfK ybiS ycfS ynhG family protein
CDO28_RS05095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS05100	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDO28_RS05110	COG2183	response to ionizing radiation
CDO28_RS05115	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO28_RS05120	COG0584	glycerophosphoryl diester phosphodiesterase
CDO28_RS05140	COG0431	NADPH-dependent FMN reductase
CDO28_RS05145	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDO28_RS05150	COG0571	ribonuclease III activity
CDO28_RS05155	COG0681	Belongs to the peptidase S26 family
CDO28_RS05160	COG0736	holo-[acyl-carrier-protein] synthase activity
CDO28_RS05190	COG1758	RNA polymerase activity
CDO28_RS05210	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDO28_RS05215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO28_RS05220	COG0741	lytic transglycosylase activity
CDO28_RS05230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDO28_RS05235	COG4974	Belongs to the 'phage' integrase family
CDO28_RS05240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDO28_RS05250	COG3549	Plasmid maintenance system killer
CDO28_RS05255	COG3093	addiction module antidote protein HigA
CDO28_RS05270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO28_RS05285	COG0625	glutathione transferase activity
CDO28_RS05300	COG1742	UPF0060 membrane protein
CDO28_RS05305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDO28_RS05315	COG0463	Glycosyl transferase, family 2
CDO28_RS05320	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO28_RS05330	COG1733	regulation of RNA biosynthetic process
CDO28_RS05340	COG4176	ABC-type proline glycine betaine transport system permease component
CDO28_RS05360	COG0443	Heat shock 70 kDa protein
CDO28_RS05365	COG1573	uracil-dna glycosylase
CDO28_RS05380	COG2814	Major facilitator Superfamily
CDO28_RS05390	COG0308	aminopeptidase N
CDO28_RS05395	COG2202	Pas domain
CDO28_RS05395	COG2205	protein histidine kinase activity
CDO28_RS05400	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDO28_RS05405	COG2205	protein histidine kinase activity
CDO28_RS05410	COG0745	RESPONSE REGULATOR receiver
CDO28_RS05415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO28_RS05420	COG3088	subunit of a heme lyase
CDO28_RS05425	COG1138	Cytochrome C-type biogenesis protein
CDO28_RS05430	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CDO28_RS05435	COG4235	cytochrome complex assembly
CDO28_RS05475	COG2983	Belongs to the UPF0260 family
CDO28_RS05480	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO28_RS05525	COG2205	protein histidine kinase activity
CDO28_RS05535	COG2166	iron-sulfur cluster assembly
CDO28_RS05540	COG4957	zinc ion binding
CDO28_RS05545	COG1320	monovalent cation:proton antiporter activity
CDO28_RS05550	COG2212	antiporter activity
CDO28_RS05555	COG1863	multisubunit Na H antiporter MnhE subunit
CDO28_RS05560	COG0651	ATP synthesis coupled electron transport
CDO28_RS05565	COG1006	Multisubunit Na H antiporter MnhC subunit
CDO28_RS05570	COG2111	Na H antiporter
CDO28_RS05575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO28_RS05575	COG2111	Na H antiporter
CDO28_RS05580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO28_RS05590	COG1272	protein, Hemolysin III
CDO28_RS05605	COG2514	catechol 2,3-dioxygenase activity
CDO28_RS05620	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CDO28_RS05625	COG4993	Dehydrogenase
CDO28_RS05635	COG0789	Transcriptional regulator
CDO28_RS05645	COG2010	Cytochrome c
CDO28_RS05665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDO28_RS05700	COG4106	trans-aconitate 2-methyltransferase activity
CDO28_RS05710	COG0656	L-ascorbic acid biosynthetic process
CDO28_RS05720	COG0433	COG0433 Predicted ATPase
CDO28_RS05725	COG2824	Alkylphosphonate utilization operon protein PhnA
CDO28_RS05730	COG1764	response to oxidative stress
CDO28_RS05735	COG1846	Transcriptional regulator
CDO28_RS05740	COG1388	LysM domain
CDO28_RS05740	COG1376	ErfK ybiS ycfS ynhG family protein
CDO28_RS05755	COG0583	DNA-binding transcription factor activity
CDO28_RS05785	COG3300	MHYT domain
CDO28_RS05785	COG5001	Diguanylate cyclase
CDO28_RS05795	COG1309	transcriptional regulator
CDO28_RS05800	COG3119	arylsulfatase activity
CDO28_RS05805	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS05815	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CDO28_RS05830	COG0175	sulfate reduction
CDO28_RS05835	COG0175	sulfate reduction
CDO28_RS05840	COG2895	sulfate adenylyltransferase (ATP) activity
CDO28_RS05865	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CDO28_RS05865	COG3264	Mechanosensitive ion channel
CDO28_RS05900	COG0574	Belongs to the PEP-utilizing enzyme family
CDO28_RS05900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDO28_RS05905	COG1196	nuclear chromosome segregation
CDO28_RS05925	COG1194	a g-specific adenine glycosylase
CDO28_RS05935	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CDO28_RS05945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO28_RS05965	COG0612	Peptidase, M16
CDO28_RS05970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO28_RS05975	COG5001	Diguanylate cyclase
CDO28_RS05980	COG1678	Uncharacterized ACR, COG1678
CDO28_RS05990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDO28_RS05990	COG0678	peroxiredoxin activity
CDO28_RS05995	COG0328	RNA-DNA hybrid ribonuclease activity
CDO28_RS06000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDO28_RS06005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDO28_RS06010	COG3346	SURF1 family
CDO28_RS06030	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CDO28_RS06040	COG0109	protoheme IX farnesyltransferase activity
CDO28_RS06045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO28_RS06050	COG1565	acr, cog1565
CDO28_RS06050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO28_RS06065	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDO28_RS06065	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDO28_RS06070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDO28_RS06085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDO28_RS06090	COG0484	heat shock protein binding
CDO28_RS06100	COG0259	pyridoxamine-phosphate oxidase activity
CDO28_RS06115	COG0312	modulator of DNA gyrase
CDO28_RS06120	COG3214	Protein conserved in bacteria
CDO28_RS06125	COG1122	ATPase activity
CDO28_RS06130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDO28_RS06135	COG1268	BioY protein
CDO28_RS06140	COG0318	PFAM AMP-dependent synthetase and ligase
CDO28_RS06145	COG0183	Belongs to the thiolase family
CDO28_RS06155	COG1063	alcohol dehydrogenase
CDO28_RS06160	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDO28_RS06165	COG1722	exodeoxyribonuclease VII activity
CDO28_RS06170	COG1741	Belongs to the pirin family
CDO28_RS06175	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDO28_RS06185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDO28_RS06205	COG1960	acyl-CoA dehydrogenase activity
CDO28_RS06230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDO28_RS06235	COG4638	Rieske (2fe-2S)
CDO28_RS06245	COG0009	L-threonylcarbamoyladenylate synthase
CDO28_RS06265	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDO28_RS06270	COG3713	MltA-interacting MipA family protein
CDO28_RS06275	COG4977	sequence-specific DNA binding
CDO28_RS06280	COG2223	nitrite transmembrane transporter activity
CDO28_RS06290	COG5001	Diguanylate cyclase
CDO28_RS06295	COG0151	Belongs to the GarS family
CDO28_RS06305	COG1683	Conserved Protein
CDO28_RS06310	COG0751	glycine-tRNA ligase activity
CDO28_RS06320	COG1704	LemA family
CDO28_RS06330	COG0752	glycyl-tRNA synthetase alpha subunit
CDO28_RS06355	COG0142	geranyltranstransferase activity
CDO28_RS06365	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDO28_RS06370	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDO28_RS06390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDO28_RS06400	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDO28_RS06405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDO28_RS06410	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDO28_RS06415	COG0356	it plays a direct role in the translocation of protons across the membrane
CDO28_RS06430	COG3158	transport of potassium into the cell
CDO28_RS06435	COG0598	Magnesium transport protein CorA
CDO28_RS06440	COG0489	protein tyrosine kinase activity
CDO28_RS06445	COG2771	luxR family
CDO28_RS06455	COG1414	Transcriptional regulator
CDO28_RS06460	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS06465	COG3734	2-keto-3-deoxy-galactonokinase
CDO28_RS06470	COG0800	Aldolase
CDO28_RS06475	COG3386	PFAM SMP-30 Gluconolaconase
CDO28_RS06480	COG0129	dihydroxy-acid dehydratase activity
CDO28_RS06495	COG5598	trimethylamine methyltransferase
CDO28_RS06500	COG0583	DNA-binding transcription factor activity
CDO28_RS06505	COG3300	MHYT domain
CDO28_RS06505	COG5001	Diguanylate cyclase
CDO28_RS06515	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDO28_RS06530	COG1663	tetraacyldisaccharide 4'-kinase activity
CDO28_RS06540	COG1519	Transferase
CDO28_RS06550	COG0483	inositol monophosphate 1-phosphatase activity
CDO28_RS06555	COG0312	modulator of DNA gyrase
CDO28_RS06560	COG0475	glutathione-regulated potassium exporter activity
CDO28_RS06560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO28_RS06570	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
CDO28_RS06575	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO28_RS06580	COG0742	ribosomal rna small subunit methyltransferase
CDO28_RS06585	COG1187	pseudouridine synthase activity
CDO28_RS06590	COG0590	tRNA wobble adenosine to inosine editing
CDO28_RS06605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDO28_RS06610	COG0196	riboflavin kinase activity
CDO28_RS06625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO28_RS06630	COG0459	protein refolding
CDO28_RS06645	COG0625	glutathione transferase activity
CDO28_RS06650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDO28_RS06655	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDO28_RS06660	COG0124	histidyl-tRNA synthetase
CDO28_RS06675	COG1953	Uracil, thiamine, allantoin
CDO28_RS06680	COG2818	Glycosylase
CDO28_RS06685	COG1376	ErfK ybiS ycfS ynhG family protein
CDO28_RS06690	COG1388	LysM domain
CDO28_RS06690	COG1376	ErfK ybiS ycfS ynhG family protein
CDO28_RS06695	COG0247	lactate metabolic process
CDO28_RS06700	COG0277	FAD linked oxidase domain protein
CDO28_RS06705	COG0277	FAD linked oxidase domain protein
CDO28_RS06710	COG0583	DNA-binding transcription factor activity
CDO28_RS06720	COG1725	Transcriptional regulator
CDO28_RS06730	COG0306	phosphate transporter
CDO28_RS06765	COG0583	DNA-binding transcription factor activity
CDO28_RS06770	COG0753	catalase activity
CDO28_RS06775	COG0583	DNA-binding transcription factor activity
CDO28_RS06780	COG0412	Dienelactone hydrolase
CDO28_RS06800	COG0477	Major facilitator Superfamily
CDO28_RS06810	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDO28_RS06835	COG2059	Chromate
CDO28_RS06890	COG1285	pathogenesis
CDO28_RS06900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS06925	COG0784	Response regulator, receiver
CDO28_RS06940	COG0251	oxidation-reduction process
CDO28_RS06945	COG4608	Belongs to the ABC transporter superfamily
CDO28_RS06950	COG0444	Belongs to the ABC transporter superfamily
CDO28_RS06955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS06960	COG0601	transmembrane transport
CDO28_RS06965	COG0747	negative chemotaxis
CDO28_RS06970	COG1959	2 iron, 2 sulfur cluster binding
CDO28_RS06975	COG1840	ABC-type Fe3 transport system, periplasmic component
CDO28_RS06985	COG4269	membrane
CDO28_RS07020	COG2205	protein histidine kinase activity
CDO28_RS07025	COG1178	ABC-type Fe3 transport system permease component
CDO28_RS07030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO28_RS07040	COG1177	transmembrane transport
CDO28_RS07045	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO28_RS07050	COG3842	ATPase activity
CDO28_RS07060	COG1396	sequence-specific DNA binding
CDO28_RS07060	COG3800	Transcriptional regulator
CDO28_RS07065	COG2224	Isocitrate lyase
CDO28_RS07085	COG0840	transmembrane signaling receptor activity
CDO28_RS07085	COG2972	Histidine kinase
CDO28_RS07095	COG2081	HI0933 family
CDO28_RS07105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS07110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDO28_RS07115	COG0363	glucosamine-6-phosphate deaminase activity
CDO28_RS07120	COG0129	dihydroxy-acid dehydratase activity
CDO28_RS07125	COG3385	transposase activity
CDO28_RS07140	COG3842	ATPase activity
CDO28_RS07145	COG0366	Alpha amylase catalytic
CDO28_RS07150	COG0395	ABC-type sugar transport system, permease component
CDO28_RS07155	COG1175	transmembrane transport
CDO28_RS07160	COG1653	transport
CDO28_RS07165	COG1609	Transcriptional regulator
CDO28_RS07170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDO28_RS07205	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO28_RS07210	COG4794	Type iii secretion
CDO28_RS07215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CDO28_RS07220	COG5443	negative regulation of bacterial-type flagellum assembly
CDO28_RS07240	COG1749	Flagellar hook protein flgE
CDO28_RS07265	COG1360	Flagellar Motor Protein
CDO28_RS07275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO28_RS07280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO28_RS07285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO28_RS07290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO28_RS07295	COG1338	Plays a role in the flagellum-specific transport system
CDO28_RS07305	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CDO28_RS07315	COG1706	bacterial-type flagellum-dependent cell motility
CDO28_RS07320	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CDO28_RS07325	COG4786	Flagellar basal body rod
CDO28_RS07330	COG1677	Flagellar hook-basal body complex protein FliE
CDO28_RS07335	COG1558	bacterial-type flagellum-dependent cell motility
CDO28_RS07340	COG1815	bacterial-type flagellum-dependent cell motility
CDO28_RS07350	COG1157	protein secretion by the type III secretion system
CDO28_RS07355	COG4786	Flagellar basal body rod
CDO28_RS07365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDO28_RS07370	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO28_RS07375	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO28_RS07380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO28_RS07385	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO28_RS07400	COG2771	luxR family
CDO28_RS07405	COG1766	The M ring may be actively involved in energy transduction
CDO28_RS07430	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CDO28_RS07435	COG0745	RESPONSE REGULATOR receiver
CDO28_RS07440	COG2201	protein-glutamate methylesterase activity
CDO28_RS07445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CDO28_RS07450	COG0835	chemotaxis
CDO28_RS07455	COG2198	Histidine kinase
CDO28_RS07455	COG0643	Histidine kinase
CDO28_RS07460	COG0745	RESPONSE REGULATOR receiver
CDO28_RS07470	COG0840	transmembrane signaling receptor activity
CDO28_RS07480	COG3254	rhamnose metabolic process
CDO28_RS07490	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS07495	COG1129	ABC transporter
CDO28_RS07505	COG1349	DNA-binding transcription factor activity
CDO28_RS07510	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS07510	COG3347	Dehydrogenase
CDO28_RS07515	COG4952	isomerase
CDO28_RS07530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDO28_RS07580	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDO28_RS07585	COG0424	maF-like protein
CDO28_RS07590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDO28_RS07600	COG5328	Belongs to the UPF0262 family
CDO28_RS07605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDO28_RS07615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDO28_RS07645	COG2132	Multicopper oxidase
CDO28_RS07675	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDO28_RS07680	COG1335	isochorismatase
CDO28_RS07695	COG0156	8-amino-7-oxononanoate synthase activity
CDO28_RS07700	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS07705	COG1368	sulfuric ester hydrolase activity
CDO28_RS07715	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDO28_RS07715	COG0517	IMP dehydrogenase activity
CDO28_RS07720	COG1959	2 iron, 2 sulfur cluster binding
CDO28_RS07750	COG1309	transcriptional regulator
CDO28_RS07760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO28_RS07765	COG4215	(ABC) transporter
CDO28_RS07775	COG1473	amidohydrolase
CDO28_RS07780	COG1271	oxidase subunit
CDO28_RS07785	COG1294	oxidase, subunit
CDO28_RS07800	COG0436	Aminotransferase
CDO28_RS07805	COG1970	mechanosensitive ion channel activity
CDO28_RS07830	COG0167	dihydroorotate dehydrogenase activity
CDO28_RS07835	COG0534	Mate efflux family protein
CDO28_RS07860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO28_RS07865	COG1959	2 iron, 2 sulfur cluster binding
CDO28_RS07870	COG1201	RNA secondary structure unwinding
CDO28_RS07895	COG0730	response to heat
CDO28_RS07905	COG1960	acyl-CoA dehydrogenase activity
CDO28_RS07910	COG0183	Belongs to the thiolase family
CDO28_RS07915	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO28_RS07915	COG1024	Enoyl-CoA hydratase
CDO28_RS07930	COG0387	Pfam Sodium calcium exchanger
CDO28_RS07935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDO28_RS07955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO28_RS07965	COG0717	Belongs to the dCTP deaminase family
CDO28_RS07975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDO28_RS07980	COG2967	ApaG domain
CDO28_RS07990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDO28_RS07995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO28_RS08005	COG0745	RESPONSE REGULATOR receiver
CDO28_RS08010	COG0704	Plays a role in the regulation of phosphate uptake
CDO28_RS08015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDO28_RS08025	COG0573	inorganic phosphate transmembrane transporter activity
CDO28_RS08035	COG5002	protein histidine kinase activity
CDO28_RS08040	COG2326	polyphosphate kinase activity
CDO28_RS08065	COG4589	Belongs to the CDS family
CDO28_RS08080	COG0628	permease
CDO28_RS08085	COG2814	Major facilitator Superfamily
CDO28_RS08090	COG0318	PFAM AMP-dependent synthetase and ligase
CDO28_RS08095	COG0166	Belongs to the GPI family
CDO28_RS08105	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDO28_RS08110	COG0418	dihydroorotase activity
CDO28_RS08115	COG1072	(Pantothenic acid kinase))
CDO28_RS08145	COG2259	Doxx family
CDO28_RS08155	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO28_RS08195	COG0667	Aldo Keto reductase
CDO28_RS08255	COG1304	FMN binding
CDO28_RS08285	COG5002	protein histidine kinase activity
CDO28_RS08310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CDO28_RS08315	COG0594	ribonuclease P activity
CDO28_RS08320	COG0706	membrane insertase activity
CDO28_RS08330	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDO28_RS08340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO28_RS08350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDO28_RS08360	COG2169	Transcriptional regulator
CDO28_RS08360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO28_RS08380	COG2171	N-acyltransferase activity
CDO28_RS08390	COG0513	Belongs to the DEAD box helicase family
CDO28_RS08400	COG0583	DNA-binding transcription factor activity
CDO28_RS08405	COG0657	acetylesterase activity
CDO28_RS08420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO28_RS08435	COG0101	tRNA pseudouridine synthase activity
CDO28_RS08440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO28_RS08445	COG0242	peptide deformylase activity
CDO28_RS08455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO28_RS08460	COG0840	transmembrane signaling receptor activity
CDO28_RS08465	COG1957	nucleoside hydrolase
CDO28_RS08470	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO28_RS08480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDO28_RS08485	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDO28_RS08490	COG1396	sequence-specific DNA binding
CDO28_RS08495	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CDO28_RS08500	COG4535	Mg2 and Co2 transporter CorC
CDO28_RS08505	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDO28_RS08510	COG1702	phosphate starvation-inducible protein PhoH
CDO28_RS08515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDO28_RS08535	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDO28_RS08545	COG0180	Tryptophanyl-tRNA synthetase
CDO28_RS08555	COG0728	peptidoglycan biosynthetic process
CDO28_RS08560	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CDO28_RS08565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDO28_RS08570	COG0280	phosphate acetyltransferase
CDO28_RS08570	COG0281	malic enzyme
CDO28_RS08580	COG2205	protein histidine kinase activity
CDO28_RS08580	COG5002	protein histidine kinase activity
CDO28_RS08580	COG0784	Response regulator, receiver
CDO28_RS08585	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDO28_RS08590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO28_RS08595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDO28_RS08595	COG0116	Belongs to the methyltransferase superfamily
CDO28_RS08610	COG0776	regulation of translation
CDO28_RS08615	COG0616	signal peptide processing
CDO28_RS08625	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDO28_RS08630	COG1137	ATPase activity
CDO28_RS08635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO28_RS08640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDO28_RS08645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO28_RS08655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDO28_RS08660	COG1420	regulation of RNA biosynthetic process
CDO28_RS08665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDO28_RS08675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDO28_RS08680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDO28_RS08695	COG4941	Belongs to the sigma-70 factor family
CDO28_RS08700	COG3795	YCII-related domain
CDO28_RS08705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDO28_RS08715	COG0268	Binds directly to 16S ribosomal RNA
CDO28_RS08720	COG1024	Enoyl-CoA hydratase
CDO28_RS08725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDO28_RS08730	COG2226	methyltransferase
CDO28_RS08735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDO28_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS08765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDO28_RS08800	COG1082	Xylose isomerase domain protein TIM barrel
CDO28_RS08805	COG3718	enzyme involved in inositol metabolism
CDO28_RS08815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS08830	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDO28_RS08835	COG0756	dUTP diphosphatase activity
CDO28_RS08840	COG1522	sequence-specific DNA binding
CDO28_RS08845	COG0697	spore germination
CDO28_RS08860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDO28_RS08870	COG0189	ligase activity
CDO28_RS08875	COG0792	nuclease activity
CDO28_RS08880	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDO28_RS08890	COG3963	phosphatidate phosphatase activity
CDO28_RS08900	COG0284	orotidine-5'-phosphate decarboxylase activity
CDO28_RS08910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS08920	COG1968	undecaprenyl-diphosphatase activity
CDO28_RS08930	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDO28_RS08940	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDO28_RS08975	COG1247	-acetyltransferase
CDO28_RS08990	COG0519	Catalyzes the synthesis of GMP from XMP
CDO28_RS08990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDO28_RS09025	COG1448	Aminotransferase
CDO28_RS09030	COG1393	Belongs to the ArsC family
CDO28_RS09045	COG0625	glutathione transferase activity
CDO28_RS09050	COG2309	aminopeptidase activity
CDO28_RS09055	COG0697	spore germination
CDO28_RS09060	COG1846	Transcriptional regulator
CDO28_RS09065	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDO28_RS09070	COG1570	exodeoxyribonuclease VII activity
CDO28_RS09090	COG0667	Aldo Keto reductase
CDO28_RS09115	COG0667	Aldo Keto reductase
CDO28_RS09125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO28_RS09125	COG0072	phenylalanine-tRNA ligase activity
CDO28_RS09130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDO28_RS09135	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDO28_RS09140	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDO28_RS09145	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDO28_RS09165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDO28_RS09170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDO28_RS09175	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CDO28_RS09180	COG1509	lysine 2,3-aminomutase activity
CDO28_RS09185	COG2885	chlorophyll binding
CDO28_RS09190	COG3932	Exopolysaccharide synthesis, ExoD
CDO28_RS09210	COG0481	GTPase activity
CDO28_RS09220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO28_RS09255	COG2801	Transposase and inactivated derivatives
CDO28_RS09255	COG3415	Transposase
CDO28_RS09270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO28_RS09275	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO28_RS09305	COG0539	negative regulation of cytoplasmic translation
CDO28_RS09310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDO28_RS09315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDO28_RS09335	COG2860	membrane
CDO28_RS09345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO28_RS09355	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDO28_RS09365	COG1185	polyribonucleotide nucleotidyltransferase activity
CDO28_RS09370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDO28_RS09380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDO28_RS09385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDO28_RS09390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDO28_RS09400	COG0195	Participates in both transcription termination and antitermination
CDO28_RS09400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDO28_RS09405	COG0779	Required for maturation of 30S ribosomal subunits
CDO28_RS09410	COG2814	Major facilitator Superfamily
CDO28_RS09415	COG2951	lytic endotransglycosylase activity
CDO28_RS09420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDO28_RS09430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDO28_RS09435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDO28_RS09450	COG2816	NAD+ diphosphatase activity
CDO28_RS09455	COG2378	regulation of single-species biofilm formation
CDO28_RS09470	COG0077	Prephenate dehydratase
CDO28_RS09470	COG1605	Chorismate mutase
CDO28_RS09475	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CDO28_RS09480	COG3474	cytochrome
CDO28_RS09485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO28_RS09505	COG2814	Major facilitator Superfamily
CDO28_RS09515	COG4771	TonB-dependent receptor
CDO28_RS09520	COG2814	Major facilitator Superfamily
CDO28_RS09525	COG1917	Cupin 2, conserved barrel domain protein
CDO28_RS09525	COG2207	Transcriptional regulator
CDO28_RS09550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO28_RS09555	COG1744	ABC transporter substrate-binding protein PnrA-like
CDO28_RS09560	COG2900	Belongs to the SlyX family
CDO28_RS09575	COG1940	carbohydrate kinase activity
CDO28_RS09580	COG3142	Participates in the control of copper homeostasis
CDO28_RS09590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDO28_RS09595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO28_RS09600	COG2188	Transcriptional regulator
CDO28_RS09605	COG2971	BadF BadG BcrA BcrD
CDO28_RS09610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDO28_RS09620	COG1175	transmembrane transport
CDO28_RS09625	COG0395	ABC-type sugar transport system, permease component
CDO28_RS09630	COG0673	inositol 2-dehydrogenase activity
CDO28_RS09640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO28_RS09645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO28_RS09665	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDO28_RS09670	COG1392	Phosphate transport regulator
CDO28_RS09675	COG0306	phosphate transporter
CDO28_RS09690	COG0484	heat shock protein binding
CDO28_RS09695	COG0443	Heat shock 70 kDa protein
CDO28_RS09700	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO28_RS09720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO28_RS09730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO28_RS09730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO28_RS09750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO28_RS09775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO28_RS09780	COG0588	phosphoglycerate mutase activity
CDO28_RS09785	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDO28_RS09790	COG1132	(ABC) transporter
CDO28_RS09795	COG0837	glucose binding
CDO28_RS09800	COG1803	Methylglyoxal synthase
CDO28_RS09805	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CDO28_RS09810	COG4166	transmembrane transport
CDO28_RS09815	COG4174	ABC transporter (Permease)
CDO28_RS09820	COG4239	(ABC) transporter, permease
CDO28_RS09825	COG4172	Belongs to the ABC transporter superfamily
CDO28_RS09835	COG0791	NLP P60 protein
CDO28_RS09845	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO28_RS09855	COG3385	transposase activity
CDO28_RS09885	COG4964	Belongs to the GSP D family
CDO28_RS09920	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CDO28_RS09925	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDO28_RS09930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDO28_RS09935	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CDO28_RS09950	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS09955	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS09960	COG3845	ABC transporter
CDO28_RS09985	COG0673	inositol 2-dehydrogenase activity
CDO28_RS10005	COG0673	inositol 2-dehydrogenase activity
CDO28_RS10010	COG1309	transcriptional regulator
CDO28_RS10015	COG1653	transport
CDO28_RS10020	COG1175	transmembrane transport
CDO28_RS10025	COG0395	ABC-type sugar transport system, permease component
CDO28_RS10030	COG0673	inositol 2-dehydrogenase activity
CDO28_RS10040	COG3842	ATPase activity
CDO28_RS10055	COG2186	Transcriptional regulator
CDO28_RS10065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS10070	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CDO28_RS10080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO28_RS10105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO28_RS10135	COG0531	amino acid
CDO28_RS10150	COG0174	glutamine synthetase
CDO28_RS10155	COG0069	glutamate synthase activity
CDO28_RS10160	COG2218	PFAM glutamate synthase alpha subunit domain protein
CDO28_RS10165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDO28_RS10170	COG4977	sequence-specific DNA binding
CDO28_RS10175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS10180	COG4311	Sarcosine oxidase, delta subunit
CDO28_RS10185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO28_RS10185	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO28_RS10195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDO28_RS10220	COG0626	cystathionine gamma-synthase activity
CDO28_RS10225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDO28_RS10285	COG4134	Bacterial extracellular solute-binding protein
CDO28_RS10290	COG4135	transport system, permease component
CDO28_RS10295	COG4136	ATPase activity
CDO28_RS10300	COG1643	Atp-dependent helicase
CDO28_RS10310	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CDO28_RS10325	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDO28_RS10335	COG2124	cytochrome p450
CDO28_RS10345	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CDO28_RS10355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CDO28_RS10360	COG0131	Imidazoleglycerol-phosphate dehydratase
CDO28_RS10370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDO28_RS10375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDO28_RS10380	COG0107	imidazoleglycerol-phosphate synthase activity
CDO28_RS10385	COG0140	phosphoribosyl-ATP diphosphatase activity
CDO28_RS10390	COG1072	(Pantothenic acid kinase))
CDO28_RS10400	COG1652	LysM domain
CDO28_RS10410	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CDO28_RS10415	COG0745	RESPONSE REGULATOR receiver
CDO28_RS10420	COG2205	protein histidine kinase activity
CDO28_RS10435	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO28_RS10435	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO28_RS10445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDO28_RS10450	COG2205	protein histidine kinase activity
CDO28_RS10455	COG3178	'Phosphotransferase
CDO28_RS10460	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDO28_RS10465	COG2887	Belongs to the helicase family. UvrD subfamily
CDO28_RS10470	COG1074	ATP-dependent DNA helicase activity
CDO28_RS10480	COG3385	transposase activity
CDO28_RS10490	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDO28_RS10495	COG0159	tryptophan synthase activity
CDO28_RS10500	COG0133	tryptophan synthase activity
CDO28_RS10505	COG0135	phosphoribosylanthranilate isomerase activity
CDO28_RS10525	COG1063	alcohol dehydrogenase
CDO28_RS10530	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS10550	COG2721	sulfolactate sulfo-lyase activity
CDO28_RS10555	COG1802	Transcriptional regulator
CDO28_RS10605	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CDO28_RS10610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDO28_RS10615	COG0237	dephospho-CoA kinase activity
CDO28_RS10620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDO28_RS10625	COG0424	maF-like protein
CDO28_RS10630	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDO28_RS10635	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDO28_RS10640	COG1981	membrane
CDO28_RS10645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDO28_RS10650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDO28_RS10655	COG0445	tRNA wobble uridine modification
CDO28_RS10660	COG0357	Ribosomal RNA small subunit methyltransferase G
CDO28_RS10685	COG0495	leucyl-tRNA aminoacylation
CDO28_RS10690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDO28_RS10710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO28_RS10720	COG0501	Belongs to the peptidase M48B family
CDO28_RS10725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO28_RS10725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDO28_RS10735	COG0138	bifunctional purine biosynthesis protein purh
CDO28_RS10750	COG2902	Dehydrogenase
CDO28_RS10760	COG0288	reversible hydration of carbon dioxide
CDO28_RS10775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDO28_RS10800	COG0671	phosphoesterase, PA-phosphatase related
CDO28_RS10805	COG0473	3-isopropylmalate dehydrogenase activity
CDO28_RS10815	COG0339	signal peptide processing
CDO28_RS10825	COG1609	Transcriptional regulator
CDO28_RS10830	COG0673	inositol 2-dehydrogenase activity
CDO28_RS10840	COG1024	Enoyl-CoA hydratase
CDO28_RS10845	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS10850	COG1653	transport
CDO28_RS10855	COG1175	transmembrane transport
CDO28_RS10860	COG0395	ABC-type sugar transport system, permease component
CDO28_RS10865	COG3842	ATPase activity
CDO28_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS10890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO28_RS10900	COG0436	Aminotransferase
CDO28_RS10915	COG5383	Protein conserved in bacteria
CDO28_RS10930	COG3459	Glycosyltransferase 36 associated
CDO28_RS10945	COG1132	(ABC) transporter
CDO28_RS10955	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDO28_RS10960	COG1126	abc transporter atp-binding protein
CDO28_RS10965	COG0765	amino acid transport
CDO28_RS10970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO28_RS10980	COG2223	nitrite transmembrane transporter activity
CDO28_RS10985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDO28_RS10995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO28_RS11000	COG0142	geranyltranstransferase activity
CDO28_RS11005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDO28_RS11010	COG0625	glutathione transferase activity
CDO28_RS11015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDO28_RS11020	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CDO28_RS11025	COG0183	Belongs to the thiolase family
CDO28_RS11030	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS11045	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDO28_RS11050	COG1329	Transcriptional regulator
CDO28_RS11055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO28_RS11065	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CDO28_RS11090	COG0488	(ABC) transporter
CDO28_RS11095	COG0765	amino acid transport
CDO28_RS11105	COG0335	large ribosomal subunit rRNA binding
CDO28_RS11115	COG0336	Belongs to the RNA methyltransferase TrmD family
CDO28_RS11120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDO28_RS11125	COG0228	four-way junction DNA binding
CDO28_RS11130	COG0287	Prephenate dehydrogenase
CDO28_RS11130	COG1605	Chorismate mutase
CDO28_RS11135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDO28_RS11140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDO28_RS11145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDO28_RS11150	COG0552	protein localization to endoplasmic reticulum
CDO28_RS11155	COG2917	probably involved in intracellular septation
CDO28_RS11175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO28_RS11180	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO28_RS11185	COG4133	protoheme IX ABC transporter activity
CDO28_RS11190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDO28_RS11205	COG0640	Transcriptional regulator
CDO28_RS11215	COG0740	serine-type endopeptidase activity
CDO28_RS11225	COG0670	Belongs to the BI1 family
CDO28_RS11235	COG4181	ATPase activity
CDO28_RS11245	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CDO28_RS11250	COG2154	pterin-4-alpha-carbinolamine dehydratase
CDO28_RS11270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDO28_RS11280	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS11295	COG0137	argininosuccinate synthase activity
CDO28_RS11300	COG0477	Major facilitator Superfamily
CDO28_RS11315	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDO28_RS11330	COG0745	RESPONSE REGULATOR receiver
CDO28_RS11345	COG1940	carbohydrate kinase activity
CDO28_RS11350	COG1940	carbohydrate kinase activity
CDO28_RS11355	COG1129	ABC transporter
CDO28_RS11360	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS11365	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS11385	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDO28_RS11390	COG1674	ftsk spoiiie
CDO28_RS11395	COG0004	ammonium transporteR
CDO28_RS11400	COG0347	Belongs to the P(II) protein family
CDO28_RS11405	COG1946	Acyl-CoA thioesterase
CDO28_RS11410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO28_RS11420	COG2835	tetraacyldisaccharide 4'-kinase activity
CDO28_RS11425	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO28_RS11430	COG3118	belongs to the thioredoxin family
CDO28_RS11445	COG0523	cobalamin synthesis protein
CDO28_RS11455	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDO28_RS11460	COG0251	oxidation-reduction process
CDO28_RS11465	COG0066	3-isopropylmalate dehydratase activity
CDO28_RS11495	COG0587	DNA-directed DNA polymerase activity
CDO28_RS11510	COG0494	nUDIX hydrolase
CDO28_RS11515	COG2861	carbohydrate metabolic process
CDO28_RS11520	COG0793	Belongs to the peptidase S41A family
CDO28_RS11530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDO28_RS11535	COG0799	negative regulation of ribosome biogenesis
CDO28_RS11540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDO28_RS11545	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDO28_RS11550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDO28_RS11555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDO28_RS11570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDO28_RS11575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDO28_RS11605	COG4249	Peptidase C14 caspase catalytic subunit p20
CDO28_RS11615	COG1217	gtp-binding protein TYPA
CDO28_RS11630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDO28_RS11645	COG0519	Catalyzes the synthesis of GMP from XMP
CDO28_RS11645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDO28_RS11670	COG0181	hydroxymethylbilane synthase activity
CDO28_RS11675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDO28_RS11680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDO28_RS11705	COG2009	succinate dehydrogenase
CDO28_RS11725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO28_RS11750	COG1175	transmembrane transport
CDO28_RS11755	COG0395	ABC-type sugar transport system, permease component
CDO28_RS11765	COG2845	Protein of unknown function (DUF459)
CDO28_RS11770	COG3549	Plasmid maintenance system killer
CDO28_RS11780	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDO28_RS11785	COG0039	L-malate dehydrogenase activity
CDO28_RS11790	COG0045	succinate-CoA ligase (ADP-forming) activity
CDO28_RS11795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDO28_RS11800	COG0567	Dehydrogenase, E1 component
CDO28_RS11805	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO28_RS11820	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS11835	COG4974	Belongs to the 'phage' integrase family
CDO28_RS11845	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDO28_RS11865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDO28_RS11880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDO28_RS11885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDO28_RS11890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDO28_RS11895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDO28_RS11900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDO28_RS11920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO28_RS11925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO28_RS11930	COG1121	(ABC) transporter
CDO28_RS11935	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDO28_RS11950	COG2233	PERMEase
CDO28_RS11955	COG2233	PERMEase
CDO28_RS11970	COG0395	ABC-type sugar transport system, permease component
CDO28_RS11980	COG3842	ATPase activity
CDO28_RS11985	COG3842	ATPase activity
CDO28_RS12005	COG0583	DNA-binding transcription factor activity
CDO28_RS12025	COG3383	formate dehydrogenase (NAD+) activity
CDO28_RS12030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDO28_RS12045	COG0835	chemotaxis
CDO28_RS12050	COG0010	Belongs to the arginase family
CDO28_RS12085	COG2267	carboxylic ester hydrolase activity
CDO28_RS12115	COG0156	8-amino-7-oxononanoate synthase activity
CDO28_RS12120	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDO28_RS12150	COG1940	carbohydrate kinase activity
CDO28_RS12155	COG4702	Belongs to the UPF0303 family
CDO28_RS12160	COG2942	2-epimerase
CDO28_RS12170	COG3328	transposase activity
CDO28_RS12185	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS12245	COG2390	Transcriptional regulator
CDO28_RS12250	COG0747	negative chemotaxis
CDO28_RS12270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS12275	COG0584	glycerophosphoryl diester phosphodiesterase
CDO28_RS12285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO28_RS12290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS12295	COG0765	amino acid transport
CDO28_RS12305	COG1126	abc transporter atp-binding protein
CDO28_RS12320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO28_RS12330	COG1802	Transcriptional regulator
CDO28_RS12340	COG5001	Diguanylate cyclase
CDO28_RS12340	COG3300	MHYT domain
CDO28_RS12365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO28_RS12385	COG2197	response regulator
CDO28_RS12405	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CDO28_RS12415	COG0625	glutathione transferase activity
CDO28_RS12435	COG0022	dehydrogenase e1 component
CDO28_RS12450	COG3585	molybdate ion transport
CDO28_RS12450	COG2005	Transcriptional regulator
CDO28_RS12455	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CDO28_RS12460	COG4149	molybdate abc transporter
CDO28_RS12470	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDO28_RS12475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO28_RS12520	COG0583	DNA-binding transcription factor activity
CDO28_RS12530	COG1320	monovalent cation:proton antiporter activity
CDO28_RS12535	COG2212	antiporter activity
CDO28_RS12540	COG1863	multisubunit Na H antiporter MnhE subunit
CDO28_RS12545	COG0651	ATP synthesis coupled electron transport
CDO28_RS12550	COG1006	Multisubunit Na H antiporter MnhC subunit
CDO28_RS12555	COG2111	Na H antiporter
CDO28_RS12555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO28_RS12565	COG1793	dna ligase
CDO28_RS12565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO28_RS12585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDO28_RS12590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDO28_RS12595	COG1253	flavin adenine dinucleotide binding
CDO28_RS12600	COG2207	Transcriptional regulator
CDO28_RS12600	COG3708	Transcriptional regulator
CDO28_RS12605	COG1309	transcriptional regulator
CDO28_RS12625	COG1609	Transcriptional regulator
CDO28_RS12630	COG1070	Carbohydrate kinase
CDO28_RS12635	COG2115	Belongs to the xylose isomerase family
CDO28_RS12645	COG0673	inositol 2-dehydrogenase activity
CDO28_RS12655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDO28_RS12660	COG2011	ABC-type metal ion transport system permease component
CDO28_RS12670	COG1054	Belongs to the UPF0176 family
CDO28_RS12680	COG2954	triphosphatase activity
CDO28_RS12685	COG0800	Aldolase
CDO28_RS12720	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CDO28_RS12730	COG0583	DNA-binding transcription factor activity
CDO28_RS12745	COG1280	lysine exporter protein (LysE YggA)
CDO28_RS12760	COG0523	cobalamin synthesis protein
CDO28_RS12770	COG1846	Transcriptional regulator
CDO28_RS12775	COG1609	Transcriptional regulator
CDO28_RS12780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO28_RS12785	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDO28_RS12790	COG5001	Diguanylate cyclase
CDO28_RS12830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDO28_RS12840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS12850	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO28_RS12850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO28_RS12875	COG1523	belongs to the glycosyl hydrolase 13 family
CDO28_RS12880	COG0033	Phosphoglucomutase
CDO28_RS12885	COG0297	glycogen (starch) synthase activity
CDO28_RS12890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDO28_RS12895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDO28_RS12900	COG0058	SHG alpha-glucan phosphorylase activity
CDO28_RS12910	COG1305	Transglutaminase-like
CDO28_RS12920	COG0667	Aldo Keto reductase
CDO28_RS12925	COG0583	DNA-binding transcription factor activity
CDO28_RS12980	COG0129	dihydroxy-acid dehydratase activity
CDO28_RS13010	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO28_RS13020	COG4172	Belongs to the ABC transporter superfamily
CDO28_RS13025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS13030	COG0601	transmembrane transport
CDO28_RS13035	COG2267	carboxylic ester hydrolase activity
CDO28_RS13040	COG2197	response regulator
CDO28_RS13060	COG0070	glutamate synthase
CDO28_RS13060	COG0067	glutamate synthase
CDO28_RS13060	COG0069	glutamate synthase activity
CDO28_RS13075	COG2951	lytic endotransglycosylase activity
CDO28_RS13080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO28_RS13090	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDO28_RS13095	COG0330	HflC and HflK could
CDO28_RS13100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDO28_RS13105	COG0737	Belongs to the 5'-nucleotidase family
CDO28_RS13115	COG5310	Homospermidine synthase
CDO28_RS13130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO28_RS13140	COG2204	response regulator
CDO28_RS13145	COG3108	Peptidase M15
CDO28_RS13150	COG3750	Belongs to the UPF0335 family
CDO28_RS13170	COG0469	pyruvate kinase activity
CDO28_RS13175	COG0457	Tetratricopeptide repeat
CDO28_RS13180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDO28_RS13185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDO28_RS13190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDO28_RS13205	COG0640	Transcriptional regulator
CDO28_RS13225	COG0483	inositol monophosphate 1-phosphatase activity
CDO28_RS13240	COG1132	(ABC) transporter
CDO28_RS13245	COG0254	rRNA binding
CDO28_RS13275	COG0384	phenazine biosynthesis protein PhzF
CDO28_RS13280	COG3588	fructose-bisphosphate aldolase
CDO28_RS13285	COG0126	phosphoglycerate kinase activity
CDO28_RS13335	COG1692	metallophosphoesterase
CDO28_RS13340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO28_RS13355	COG0217	transcriptional regulatory protein
CDO28_RS13360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO28_RS13365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDO28_RS13370	COG0632	four-way junction helicase activity
CDO28_RS13375	COG2255	four-way junction helicase activity
CDO28_RS13380	COG1408	metallophosphoesterase
CDO28_RS13400	COG0824	Thioesterase
CDO28_RS13425	COG0823	Involved in the tonB-independent uptake of proteins
CDO28_RS13430	COG2885	chlorophyll binding
CDO28_RS13440	COG0037	tRNA processing
CDO28_RS13445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDO28_RS13450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDO28_RS13470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO28_RS13480	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDO28_RS13490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO28_RS13495	COG0564	pseudouridine synthase activity
CDO28_RS13555	COG0482	sulfurtransferase activity
CDO28_RS13610	COG3314	Sporulation integral membrane protein YlbJ
CDO28_RS13615	COG2986	histidine ammonia-lyase
CDO28_RS13620	COG4175	Glycine betaine
CDO28_RS13620	COG0517	IMP dehydrogenase activity
CDO28_RS13625	COG4176	ABC-type proline glycine betaine transport system permease component
CDO28_RS13635	COG0402	S-adenosylhomocysteine deaminase activity
CDO28_RS13645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO28_RS13650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO28_RS13655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO28_RS13660	COG1522	sequence-specific DNA binding
CDO28_RS13665	COG2207	Transcriptional regulator
CDO28_RS13670	COG1064	alcohol dehydrogenase
CDO28_RS13680	COG1473	amidohydrolase
CDO28_RS13685	COG1686	Belongs to the peptidase S11 family
CDO28_RS13690	COG0523	cobalamin synthesis protein
CDO28_RS13710	COG3034	peptidoglycan biosynthetic process
CDO28_RS13715	COG0825	malonyl-CoA metabolic process
CDO28_RS13720	COG4974	Belongs to the 'phage' integrase family
CDO28_RS13730	COG3609	addiction module antidote protein, CC2985 family
CDO28_RS13740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDO28_RS13745	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDO28_RS13750	COG4536	flavin adenine dinucleotide binding
CDO28_RS13780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CDO28_RS13785	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDO28_RS13805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO28_RS13810	COG2226	methyltransferase
CDO28_RS13815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO28_RS13820	COG0287	Prephenate dehydrogenase
CDO28_RS13830	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CDO28_RS13850	COG2884	Cell division ATP-binding protein ftsE
CDO28_RS13860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO28_RS13895	COG0165	Argininosuccinate lyase
CDO28_RS13900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO28_RS13905	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO28_RS13910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDO28_RS13915	COG2086	electron transfer activity
CDO28_RS13925	COG2096	Adenosyltransferase
CDO28_RS13935	COG0300	oxidoreductase activity
CDO28_RS13945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDO28_RS13980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO28_RS14000	COG0653	protein targeting
CDO28_RS14005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO28_RS14010	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDO28_RS14020	COG0494	nUDIX hydrolase
CDO28_RS14035	COG2226	methyltransferase
CDO28_RS14050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO28_RS14060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDO28_RS14070	COG0527	aspartate kinase activity
CDO28_RS14075	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CDO28_RS14080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDO28_RS14085	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO28_RS14100	COG0542	response to heat
CDO28_RS14105	COG0739	heme binding
CDO28_RS14145	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO28_RS14150	COG0583	DNA-binding transcription factor activity
CDO28_RS14155	COG0723	plastoquinol--plastocyanin reductase activity
CDO28_RS14170	COG1802	Transcriptional regulator
CDO28_RS14175	COG4608	Belongs to the ABC transporter superfamily
CDO28_RS14180	COG0444	Belongs to the ABC transporter superfamily
CDO28_RS14185	COG1228	amidohydrolase
CDO28_RS14195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS14200	COG0601	transmembrane transport
CDO28_RS14220	COG0402	S-adenosylhomocysteine deaminase activity
CDO28_RS14230	COG1335	isochorismatase
CDO28_RS14255	COG0683	leucine binding
CDO28_RS14260	COG1335	isochorismatase
CDO28_RS14275	COG0174	glutamine synthetase
CDO28_RS14315	COG0477	Major facilitator Superfamily
CDO28_RS14320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO28_RS14325	COG1070	Carbohydrate kinase
CDO28_RS14330	COG2188	Transcriptional regulator
CDO28_RS14335	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS14340	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS14345	COG1129	ABC transporter
CDO28_RS14350	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS14355	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS14370	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDO28_RS14375	COG1737	Transcriptional regulator
CDO28_RS14380	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDO28_RS14385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO28_RS14395	COG0800	Aldolase
CDO28_RS14400	COG2140	Oxalate decarboxylase
CDO28_RS14405	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS14410	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS14420	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS14425	COG1802	Transcriptional regulator
CDO28_RS14435	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS14450	COG1129	ABC transporter
CDO28_RS14460	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS14465	COG0583	DNA-binding transcription factor activity
CDO28_RS14470	COG0601	transmembrane transport
CDO28_RS14495	COG1473	amidohydrolase
CDO28_RS14515	COG1129	ABC transporter
CDO28_RS14520	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS14545	COG1063	alcohol dehydrogenase
CDO28_RS14585	COG1845	cytochrome c oxidase, subunit III
CDO28_RS14590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO28_RS14595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO28_RS14605	COG3842	ATPase activity
CDO28_RS14610	COG0395	ABC-type sugar transport system, permease component
CDO28_RS14625	COG0626	cystathionine gamma-synthase activity
CDO28_RS14630	COG1725	Transcriptional regulator
CDO28_RS14635	COG3328	transposase activity
CDO28_RS14645	COG0174	glutamine synthetase
CDO28_RS14650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS14680	COG0436	Aminotransferase
CDO28_RS14700	COG3842	ATPase activity
CDO28_RS14705	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO28_RS14715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO28_RS14720	COG0346	lactoylglutathione lyase activity
CDO28_RS14750	COG0400	carboxylic ester hydrolase activity
CDO28_RS14760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO28_RS14765	COG0784	Response regulator, receiver
CDO28_RS14805	COG1846	Transcriptional regulator
CDO28_RS14815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO28_RS14820	COG0829	nickel cation binding
CDO28_RS14825	COG0831	urea catabolic process
CDO28_RS14830	COG3813	Protein conserved in bacteria
CDO28_RS14835	COG0832	Belongs to the urease beta subunit family
CDO28_RS14840	COG3755	Protein conserved in bacteria
CDO28_RS14845	COG1442	glycosyl transferase family 8
CDO28_RS14850	COG0804	urea catabolic process
CDO28_RS14880	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CDO28_RS14885	COG0830	nickel cation binding
CDO28_RS14890	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CDO28_RS14905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO28_RS14910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO28_RS14915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO28_RS14945	COG1309	transcriptional regulator
CDO28_RS14960	COG0583	DNA-binding transcription factor activity
CDO28_RS14965	COG1063	alcohol dehydrogenase
CDO28_RS14990	COG1175	transmembrane transport
CDO28_RS14995	COG0395	ABC-type sugar transport system, permease component
CDO28_RS15025	COG0784	Response regulator, receiver
CDO28_RS15040	COG3920	Histidine kinase
CDO28_RS15040	COG2202	Pas domain
CDO28_RS15055	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CDO28_RS15060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO28_RS15065	COG4558	Periplasmic binding protein
CDO28_RS15115	COG2346	COG2346, Truncated hemoglobins
CDO28_RS15135	COG2076	Multidrug Resistance protein
CDO28_RS15150	COG0601	transmembrane transport
CDO28_RS15155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS15160	COG0444	Belongs to the ABC transporter superfamily
CDO28_RS15165	COG4608	Belongs to the ABC transporter superfamily
CDO28_RS15170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO28_RS15175	COG0366	Alpha amylase catalytic
CDO28_RS15180	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO28_RS15185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO28_RS15220	COG1435	thymidine kinase activity
CDO28_RS15240	COG2852	Protein conserved in bacteria
CDO28_RS15245	COG3385	transposase activity
CDO28_RS15260	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDO28_RS15275	COG0512	Glutamine amidotransferase of anthranilate synthase
CDO28_RS15275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO28_RS15280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDO28_RS15285	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDO28_RS15305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDO28_RS15315	COG0740	serine-type endopeptidase activity
CDO28_RS15325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDO28_RS15330	COG4423	Transcription factor
CDO28_RS15335	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
CDO28_RS15345	COG1595	DNA-templated transcription, initiation
CDO28_RS15370	COG0435	Glutathione S-transferase
CDO28_RS15395	COG0714	Associated with various cellular activities
CDO28_RS15420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDO28_RS15440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDO28_RS15445	COG0193	aminoacyl-tRNA hydrolase activity
CDO28_RS15450	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDO28_RS15455	COG3135	benzoate transporter
CDO28_RS15465	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS15475	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CDO28_RS15480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDO28_RS15495	COG1496	oxidoreductase activity
CDO28_RS15505	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDO28_RS15525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO28_RS15530	COG2205	protein histidine kinase activity
CDO28_RS15535	COG0745	RESPONSE REGULATOR receiver
CDO28_RS15540	COG1846	Transcriptional regulator
CDO28_RS15560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO28_RS15570	COG1278	Cold shock
CDO28_RS15580	COG2133	pyrroloquinoline quinone binding
CDO28_RS15595	COG0436	Aminotransferase
CDO28_RS15605	COG2084	Dehydrogenase
CDO28_RS15610	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS15620	COG0505	Belongs to the CarA family
CDO28_RS15630	COG0358	DNA primase activity
CDO28_RS15635	COG0514	ATP-dependent DNA helicase (RecQ)
CDO28_RS15645	COG1063	alcohol dehydrogenase
CDO28_RS15650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO28_RS15670	COG5507	3-demethylubiquinone-9 3-methyltransferase
CDO28_RS15675	COG0432	Pfam Uncharacterised protein family UPF0047
CDO28_RS15690	COG2968	Membrane
CDO28_RS15725	COG1696	Membrane protein involved in D-alanine export
CDO28_RS15845	COG1024	Enoyl-CoA hydratase
CDO28_RS15910	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS15915	COG1177	transmembrane transport
CDO28_RS15920	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO28_RS15925	COG3842	ATPase activity
CDO28_RS15930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CDO28_RS15935	COG0583	DNA-binding transcription factor activity
CDO28_RS15970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS15980	COG0747	negative chemotaxis
CDO28_RS16000	COG1960	acyl-CoA dehydrogenase activity
CDO28_RS16005	COG0824	Thioesterase
CDO28_RS16005	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO28_RS16010	COG3246	L-lysine catabolic process to acetate
CDO28_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS16025	COG1177	transmembrane transport
CDO28_RS16040	COG3842	ATPase activity
CDO28_RS16045	COG2197	response regulator
CDO28_RS16055	COG1653	transport
CDO28_RS16060	COG1175	transmembrane transport
CDO28_RS16070	COG3842	ATPase activity
CDO28_RS16090	COG0235	Class ii aldolase
CDO28_RS16105	COG1070	Carbohydrate kinase
CDO28_RS16120	COG1349	DNA-binding transcription factor activity
CDO28_RS16125	COG0149	triose-phosphate isomerase activity
CDO28_RS16140	COG3328	transposase activity
CDO28_RS16145	COG4774	siderophore transport
CDO28_RS16155	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDO28_RS16160	COG3842	ATPase activity
CDO28_RS16195	COG0174	glutamine synthetase
CDO28_RS16200	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS16215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS16220	COG1376	ErfK ybiS ycfS ynhG family protein
CDO28_RS16240	COG0028	Belongs to the TPP enzyme family
CDO28_RS16250	COG2267	carboxylic ester hydrolase activity
CDO28_RS16255	COG3719	Belongs to the RNase T2 family
CDO28_RS16315	COG1280	lysine exporter protein (LysE YggA)
CDO28_RS16325	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CDO28_RS16330	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDO28_RS16350	COG2001	Belongs to the MraZ family
CDO28_RS16355	COG0275	rRNA processing
CDO28_RS16370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDO28_RS16380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDO28_RS16385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDO28_RS16395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDO28_RS16400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDO28_RS16405	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDO28_RS16410	COG0477	Major facilitator Superfamily
CDO28_RS16415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDO28_RS16420	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO28_RS16425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDO28_RS16430	COG0849	cell division
CDO28_RS16435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDO28_RS16445	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO28_RS16455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDO28_RS16465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDO28_RS16470	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO28_RS16490	COG0006	proline dipeptidase activity
CDO28_RS16510	COG2264	protein methyltransferase activity
CDO28_RS16515	COG1999	signal sequence binding
CDO28_RS16525	COG0840	transmembrane signaling receptor activity
CDO28_RS16530	COG0835	chemotaxis
CDO28_RS16550	COG3706	GGDEF domain
CDO28_RS16585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO28_RS16595	COG0277	FAD linked oxidase domain protein
CDO28_RS16605	COG3385	transposase activity
CDO28_RS16655	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDO28_RS16675	COG0330	HflC and HflK could
CDO28_RS16690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO28_RS16695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO28_RS16700	COG3830	Belongs to the UPF0237 family
CDO28_RS16700	COG0560	Phosphoserine phosphatase
CDO28_RS16705	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDO28_RS16725	COG0028	Belongs to the TPP enzyme family
CDO28_RS16730	COG0440	acetolactate synthase activity
CDO28_RS16735	COG0656	L-ascorbic acid biosynthetic process
CDO28_RS16740	COG1278	Cold shock
CDO28_RS16780	COG1595	DNA-templated transcription, initiation
CDO28_RS16800	COG3180	Ammonia monooxygenase
CDO28_RS16805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDO28_RS16810	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO28_RS16815	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO28_RS16815	COG1672	PFAM Archaeal ATPase
CDO28_RS16860	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDO28_RS16865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO28_RS16880	COG1733	regulation of RNA biosynthetic process
CDO28_RS16885	COG1794	racemase activity, acting on amino acids and derivatives
CDO28_RS16890	COG1522	sequence-specific DNA binding
CDO28_RS16895	COG1252	NADH dehydrogenase
CDO28_RS16910	COG2271	Major facilitator Superfamily
CDO28_RS16940	COG0577	efflux transmembrane transporter activity
CDO28_RS16940	COG1136	(ABC) transporter
CDO28_RS16945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO28_RS16955	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDO28_RS16975	COG1376	ErfK ybiS ycfS ynhG family protein
CDO28_RS16985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO28_RS16995	COG0667	Aldo Keto reductase
CDO28_RS17005	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDO28_RS17015	COG1278	Cold shock
CDO28_RS17030	COG4149	molybdate abc transporter
CDO28_RS17035	COG3842	ATPase activity
CDO28_RS17050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDO28_RS17065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CDO28_RS17105	COG0384	phenazine biosynthesis protein PhzF
CDO28_RS17135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO28_RS17140	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CDO28_RS17265	COG0463	Glycosyl transferase, family 2
CDO28_RS17300	COG3273	potassium ion transport
CDO28_RS17300	COG0471	metal ion transport
CDO28_RS17315	COG1196	nuclear chromosome segregation
CDO28_RS17315	COG3264	Mechanosensitive ion channel
CDO28_RS17320	COG0861	Integral membrane protein TerC family
CDO28_RS17355	COG0745	RESPONSE REGULATOR receiver
CDO28_RS17395	COG0583	DNA-binding transcription factor activity
CDO28_RS17400	COG0640	Transcriptional regulator
CDO28_RS17425	COG0646	methionine synthase
CDO28_RS17425	COG1410	methionine synthase
CDO28_RS17460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO28_RS17475	COG5012	cobalamin binding
CDO28_RS17480	COG5598	trimethylamine methyltransferase
CDO28_RS17490	COG3698	Phosphodiester glycosidase
CDO28_RS17510	COG0646	methionine synthase
CDO28_RS17510	COG1410	methionine synthase
CDO28_RS17515	COG0583	DNA-binding transcription factor activity
CDO28_RS17530	COG3609	addiction module antidote protein, CC2985 family
CDO28_RS17535	COG4175	Glycine betaine
CDO28_RS17535	COG0517	IMP dehydrogenase activity
CDO28_RS17550	COG1492	cobalamin metabolic process
CDO28_RS17555	COG0596	Alpha beta hydrolase
CDO28_RS17600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS17605	COG0601	transmembrane transport
CDO28_RS17610	COG0747	negative chemotaxis
CDO28_RS17620	COG4172	Belongs to the ABC transporter superfamily
CDO28_RS17640	COG1797	cobyrinic acid a,c-diamide synthase activity
CDO28_RS17650	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDO28_RS17655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO28_RS17660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO28_RS17670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO28_RS17680	COG1560	Kdo2-lipid A biosynthetic process
CDO28_RS17705	COG1115	amino acid carrier protein
CDO28_RS17710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDO28_RS17730	COG1175	transmembrane transport
CDO28_RS17735	COG0395	ABC-type sugar transport system, permease component
CDO28_RS17740	COG3842	ATPase activity
CDO28_RS17745	COG3250	beta-galactosidase activity
CDO28_RS17760	COG0667	Aldo Keto reductase
CDO28_RS17765	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CDO28_RS17775	COG2801	Transposase and inactivated derivatives
CDO28_RS17775	COG3415	Transposase
CDO28_RS17780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS17790	COG3507	Belongs to the glycosyl hydrolase 43 family
CDO28_RS17805	COG1121	(ABC) transporter
CDO28_RS17810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO28_RS17815	COG0735	belongs to the Fur family
CDO28_RS17825	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO28_RS17855	COG3328	transposase activity
CDO28_RS17875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO28_RS17930	COG2801	Transposase and inactivated derivatives
CDO28_RS17935	COG4372	Transposase
CDO28_RS17950	COG0582	viral genome integration into host DNA
CDO28_RS17955	COG0582	viral genome integration into host DNA
CDO28_RS17970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDO28_RS17985	COG2433	Pfam Transposase IS66
CDO28_RS18010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO28_RS18095	COG2963	transposase activity
CDO28_RS18105	COG3328	transposase activity
CDO28_RS18110	COG0067	glutamate synthase
CDO28_RS18110	COG0069	glutamate synthase activity
CDO28_RS18110	COG0070	glutamate synthase
CDO28_RS18120	COG0174	glutamine synthetase
CDO28_RS18125	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO28_RS18130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO28_RS18135	COG3555	Aspartyl Asparaginyl beta-hydroxylase
CDO28_RS18145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDO28_RS18155	COG2963	transposase activity
CDO28_RS18170	COG4372	Transposase
CDO28_RS18230	COG3328	transposase activity
CDO28_RS18255	COG3328	transposase activity
CDO28_RS18260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS18265	COG0601	transmembrane transport
CDO28_RS18275	COG4172	Belongs to the ABC transporter superfamily
CDO28_RS18285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS18310	COG5489	Protein of unknown function (DUF736)
CDO28_RS18380	COG1196	nuclear chromosome segregation
CDO28_RS18380	COG0741	lytic transglycosylase activity
CDO28_RS18380	COG0739	heme binding
CDO28_RS18405	COG4770	biotin carboxylase activity
CDO28_RS18410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDO28_RS18415	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDO28_RS18440	COG4962	Type ii secretion system protein e
CDO28_RS18445	COG3838	Conjugal transfer protein Trbc
CDO28_RS18455	COG3451	type IV secretory pathway VirB4
CDO28_RS18485	COG2948	multi-organism process
CDO28_RS18500	COG5654	RES domain protein
CDO28_RS18505	COG5642	Protein of unknown function (DUF2384)
CDO28_RS18535	COG1074	ATP-dependent DNA helicase activity
CDO28_RS18545	COG1201	RNA secondary structure unwinding
CDO28_RS18565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDO28_RS18585	COG0484	heat shock protein binding
CDO28_RS18595	COG0556	nucleotide-excision repair
CDO28_RS18650	COG0640	Transcriptional regulator
CDO28_RS18655	COG1131	(ABC) transporter
CDO28_RS18660	COG0842	Transport permease protein
CDO28_RS18675	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CDO28_RS18680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDO28_RS18685	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDO28_RS18700	COG1573	uracil-dna glycosylase
CDO28_RS18705	COG1522	sequence-specific DNA binding
CDO28_RS18715	COG2084	Dehydrogenase
CDO28_RS18730	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS18735	COG5425	PFAM Usg family protein
CDO28_RS18765	COG1763	Mo-molybdopterin cofactor biosynthetic process
CDO28_RS18770	COG0746	molybdenum cofactor guanylyltransferase activity
CDO28_RS18775	COG0697	spore germination
CDO28_RS18780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDO28_RS18790	COG1846	Transcriptional regulator
CDO28_RS18795	COG2267	carboxylic ester hydrolase activity
CDO28_RS18805	COG0114	fumarate hydratase activity
CDO28_RS18810	COG2989	Protein conserved in bacteria
CDO28_RS18815	COG0546	phosphoglycolate phosphatase activity
CDO28_RS18820	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDO28_RS18835	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CDO28_RS18865	COG1404	Belongs to the peptidase S8 family
CDO28_RS18920	COG0471	metal ion transport
CDO28_RS18920	COG3273	potassium ion transport
CDO28_RS18980	COG0640	Transcriptional regulator
CDO28_RS18995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS19000	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO28_RS19005	COG2080	2 iron, 2 sulfur cluster binding
CDO28_RS19055	COG0583	DNA-binding transcription factor activity
CDO28_RS19135	COG2200	EAL domain
CDO28_RS19135	COG2199	diguanylate cyclase activity
CDO28_RS19180	COG2814	Major facilitator Superfamily
CDO28_RS19195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CDO28_RS19205	COG0583	DNA-binding transcription factor activity
CDO28_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS19235	COG0235	Class ii aldolase
CDO28_RS19245	COG0583	DNA-binding transcription factor activity
CDO28_RS19260	COG0583	DNA-binding transcription factor activity
CDO28_RS19265	COG3311	Transcriptional regulator
CDO28_RS19280	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS19285	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS19290	COG1129	ABC transporter
CDO28_RS19295	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS19305	COG1940	carbohydrate kinase activity
CDO28_RS19315	COG1309	transcriptional regulator
CDO28_RS19340	COG1733	regulation of RNA biosynthetic process
CDO28_RS19360	COG0492	ferredoxin-NADP+ reductase activity
CDO28_RS19375	COG1309	transcriptional regulator
CDO28_RS19380	COG2267	carboxylic ester hydrolase activity
CDO28_RS19390	COG2267	carboxylic ester hydrolase activity
CDO28_RS19405	COG4638	Rieske (2fe-2S)
CDO28_RS19410	COG0583	DNA-binding transcription factor activity
CDO28_RS19420	COG1414	Transcriptional regulator
CDO28_RS19490	COG0385	Bile acid
CDO28_RS19500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDO28_RS19525	COG3177	Filamentation induced by cAMP protein fic
CDO28_RS19535	COG1280	lysine exporter protein (LysE YggA)
CDO28_RS19545	COG3311	Transcriptional regulator
CDO28_RS19585	COG4221	oxidoreductase activity
CDO28_RS19605	COG0596	Alpha beta hydrolase
CDO28_RS19630	COG0596	Alpha beta hydrolase
CDO28_RS19635	COG1764	response to oxidative stress
CDO28_RS19655	COG3609	addiction module antidote protein, CC2985 family
CDO28_RS19680	COG0583	DNA-binding transcription factor activity
CDO28_RS19685	COG0747	negative chemotaxis
CDO28_RS19700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS19770	COG4566	intracellular signal transduction
CDO28_RS19780	COG0626	cystathionine gamma-synthase activity
CDO28_RS19785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO28_RS19790	COG4597	amino acid ABC transporter
CDO28_RS19795	COG0765	amino acid transport
CDO28_RS19800	COG1126	abc transporter atp-binding protein
CDO28_RS19805	COG1335	isochorismatase
CDO28_RS19845	COG0431	NADPH-dependent FMN reductase
CDO28_RS19890	COG3609	addiction module antidote protein, CC2985 family
CDO28_RS19895	COG0402	S-adenosylhomocysteine deaminase activity
CDO28_RS19900	COG1957	nucleoside hydrolase
CDO28_RS19910	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS19915	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS19920	COG3845	ABC transporter
CDO28_RS19925	COG1744	ABC transporter substrate-binding protein PnrA-like
CDO28_RS19935	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CDO28_RS19940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO28_RS19970	COG1063	alcohol dehydrogenase
CDO28_RS19980	COG1177	transmembrane transport
CDO28_RS19995	COG3842	ATPase activity
CDO28_RS20000	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS20115	COG4372	Transposase
CDO28_RS20135	COG3321	synthase
CDO28_RS20135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO28_RS20175	COG4372	Transposase
CDO28_RS20180	COG4974	Belongs to the 'phage' integrase family
CDO28_RS20185	COG0582	viral genome integration into host DNA
CDO28_RS20190	COG4974	Belongs to the 'phage' integrase family
CDO28_RS20195	COG4372	Transposase
CDO28_RS20205	COG4372	Transposase
CDO28_RS20210	COG3436	PFAM IS66 Orf2 family protein
CDO28_RS20215	COG2963	transposase activity
CDO28_RS20225	COG0433	COG0433 Predicted ATPase
CDO28_RS20330	COG0583	DNA-binding transcription factor activity
CDO28_RS20335	COG0251	oxidation-reduction process
CDO28_RS20340	COG1902	pentaerythritol trinitrate reductase activity
CDO28_RS20350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDO28_RS20375	COG4251	negative regulation of phosphorylation
CDO28_RS20375	COG2203	Gaf domain
CDO28_RS20375	COG5001	Diguanylate cyclase
CDO28_RS20375	COG3706	GGDEF domain
CDO28_RS20395	COG0395	ABC-type sugar transport system, permease component
CDO28_RS20440	COG2205	protein histidine kinase activity
CDO28_RS20525	COG4221	oxidoreductase activity
CDO28_RS20545	COG2080	2 iron, 2 sulfur cluster binding
CDO28_RS20550	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO28_RS20555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS20580	COG0730	response to heat
CDO28_RS20595	COG3845	ABC transporter
CDO28_RS20600	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS20605	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS20610	COG0402	S-adenosylhomocysteine deaminase activity
CDO28_RS20635	COG1309	transcriptional regulator
CDO28_RS20645	COG0488	(ABC) transporter
CDO28_RS20655	COG1764	response to oxidative stress
CDO28_RS20660	COG1414	Transcriptional regulator
CDO28_RS20665	COG1475	DNA binding
CDO28_RS20670	COG1192	Involved in chromosome partitioning
CDO28_RS20685	COG0243	molybdopterin cofactor binding
CDO28_RS20685	COG3383	formate dehydrogenase (NAD+) activity
CDO28_RS20690	COG3383	formate dehydrogenase (NAD+) activity
CDO28_RS20690	COG0243	molybdopterin cofactor binding
CDO28_RS20695	COG0437	4 iron, 4 sulfur cluster binding
CDO28_RS20700	COG2864	formate dehydrogenase
CDO28_RS20760	COG1305	Transglutaminase-like
CDO28_RS20785	COG0488	(ABC) transporter
CDO28_RS20790	COG0583	DNA-binding transcription factor activity
CDO28_RS20820	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS20825	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS20830	COG4948	Mandelate Racemase Muconate Lactonizing
CDO28_RS20840	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS20855	COG2186	Transcriptional regulator
CDO28_RS20865	COG1802	Transcriptional regulator
CDO28_RS20895	COG1609	Transcriptional regulator
CDO28_RS20900	COG0765	amino acid transport
CDO28_RS20905	COG0765	amino acid transport
CDO28_RS20910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO28_RS20915	COG1126	abc transporter atp-binding protein
CDO28_RS20920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO28_RS20930	COG0251	oxidation-reduction process
CDO28_RS20950	COG0583	DNA-binding transcription factor activity
CDO28_RS20955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO28_RS20960	COG0747	negative chemotaxis
CDO28_RS20965	COG0601	transmembrane transport
CDO28_RS20970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS20975	COG0444	Belongs to the ABC transporter superfamily
CDO28_RS20980	COG4172	Belongs to the ABC transporter superfamily
CDO28_RS20985	COG4691	Plasmid stability protein
CDO28_RS20990	COG1487	ribonuclease activity
CDO28_RS21050	COG1278	Cold shock
CDO28_RS21060	COG3239	Fatty acid desaturase
CDO28_RS21080	COG0628	permease
CDO28_RS21085	COG5001	Diguanylate cyclase
CDO28_RS21085	COG3300	MHYT domain
CDO28_RS21095	COG1404	Belongs to the peptidase S8 family
CDO28_RS21120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO28_RS21125	COG0318	PFAM AMP-dependent synthetase and ligase
CDO28_RS21145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS21150	COG1802	Transcriptional regulator
CDO28_RS21155	COG4964	Belongs to the GSP D family
CDO28_RS21175	COG2226	methyltransferase
CDO28_RS21215	COG1278	Cold shock
CDO28_RS21220	COG0477	Major facilitator Superfamily
CDO28_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS21270	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS21275	COG1129	ABC transporter
CDO28_RS21280	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS21285	COG4585	Histidine kinase
CDO28_RS21315	COG1129	ABC transporter
CDO28_RS21330	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS21335	COG1802	Transcriptional regulator
CDO28_RS21355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDO28_RS21365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO28_RS21375	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CDO28_RS21380	COG0129	dihydroxy-acid dehydratase activity
CDO28_RS21385	COG2084	Dehydrogenase
CDO28_RS21390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS21395	COG0277	FAD linked oxidase domain protein
CDO28_RS21400	COG2186	Transcriptional regulator
CDO28_RS21410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO28_RS21415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS21420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS21445	COG0657	acetylesterase activity
CDO28_RS21455	COG1454	alcohol dehydrogenase
CDO28_RS21460	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CDO28_RS21465	COG1802	Transcriptional regulator
CDO28_RS21470	COG1129	ABC transporter
CDO28_RS21475	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS21480	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS21485	COG0693	protein deglycase activity
CDO28_RS21525	COG4634	DNA integration
CDO28_RS21535	COG2442	InterPro IPR007367
CDO28_RS21650	COG1086	Polysaccharide biosynthesis protein
CDO28_RS21655	COG0583	DNA-binding transcription factor activity
CDO28_RS21660	COG3077	Addiction module antitoxin, RelB DinJ family
CDO28_RS21705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO28_RS21715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO28_RS21805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO28_RS21860	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS21865	COG0297	glycogen (starch) synthase activity
CDO28_RS21905	COG1917	Cupin 2, conserved barrel domain protein
CDO28_RS21905	COG2169	Transcriptional regulator
CDO28_RS21915	COG3077	Addiction module antitoxin, RelB DinJ family
CDO28_RS21935	COG3920	Histidine kinase
CDO28_RS21940	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CDO28_RS21960	COG1116	anion transmembrane transporter activity
CDO28_RS21970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO28_RS22040	COG3734	2-keto-3-deoxy-galactonokinase
CDO28_RS22050	COG4948	Mandelate Racemase Muconate Lactonizing
CDO28_RS22060	COG1175	transmembrane transport
CDO28_RS22065	COG0395	ABC-type sugar transport system, permease component
CDO28_RS22080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS22090	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS22120	COG1349	DNA-binding transcription factor activity
CDO28_RS22140	COG3328	transposase activity
CDO28_RS22185	COG4584	PFAM Integrase catalytic
CDO28_RS22255	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO28_RS22300	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS22320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO28_RS22325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO28_RS22335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDO28_RS22350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDO28_RS22360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDO28_RS22365	COG0492	ferredoxin-NADP+ reductase activity
CDO28_RS22370	COG0459	protein refolding
CDO28_RS22375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO28_RS22400	COG4166	transmembrane transport
CDO28_RS22405	COG0601	transmembrane transport
CDO28_RS22410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS22430	COG4372	Transposase
CDO28_RS22455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDO28_RS22460	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO28_RS22470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO28_RS22490	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO28_RS22495	COG0492	ferredoxin-NADP+ reductase activity
CDO28_RS22510	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO28_RS22545	COG3005	denitrification pathway
CDO28_RS22660	COG0601	transmembrane transport
CDO28_RS22665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS22675	COG4608	Belongs to the ABC transporter superfamily
CDO28_RS22690	COG2963	transposase activity
CDO28_RS22705	COG4584	PFAM Integrase catalytic
CDO28_RS22780	COG2010	Cytochrome c
CDO28_RS22820	COG1278	Cold shock
CDO28_RS22845	COG1115	amino acid carrier protein
CDO28_RS22875	COG2267	carboxylic ester hydrolase activity
CDO28_RS22885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO28_RS22890	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS22910	COG0395	ABC-type sugar transport system, permease component
CDO28_RS22990	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO28_RS22995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO28_RS23010	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDO28_RS23015	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDO28_RS23025	COG1433	Dinitrogenase iron-molybdenum cofactor
CDO28_RS23030	COG5420	small protein containing a coiled-coil domain
CDO28_RS23035	COG3383	formate dehydrogenase (NAD+) activity
CDO28_RS23120	COG0175	sulfate reduction
CDO28_RS23125	COG2895	sulfate adenylyltransferase (ATP) activity
CDO28_RS23125	COG0529	Catalyzes the synthesis of activated sulfate
CDO28_RS23195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO28_RS23215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO28_RS23245	COG3012	SEC-C Motif Domain Protein
CDO28_RS23325	COG3505	Type IV secretory pathway VirD4
CDO28_RS23350	COG0668	transmembrane transport
CDO28_RS23380	COG4566	intracellular signal transduction
CDO28_RS23385	COG4566	intracellular signal transduction
CDO28_RS23390	COG3119	arylsulfatase activity
CDO28_RS23400	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDO28_RS23405	COG2843	Capsule synthesis protein
CDO28_RS23415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS23420	COG0601	transmembrane transport
CDO28_RS23455	COG2771	luxR family
CDO28_RS23480	COG0583	DNA-binding transcription factor activity
CDO28_RS23500	COG2801	Transposase and inactivated derivatives
CDO28_RS23505	COG2826	transposase and inactivated derivatives, IS30 family
CDO28_RS23510	COG2801	Transposase and inactivated derivatives
CDO28_RS23530	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CDO28_RS23550	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS23555	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS23565	COG0583	DNA-binding transcription factor activity
CDO28_RS23575	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS23590	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO28_RS23595	COG3181	Tripartite tricarboxylate transporter family receptor
CDO28_RS23605	COG3386	PFAM SMP-30 Gluconolaconase
CDO28_RS23620	COG1129	ABC transporter
CDO28_RS23625	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS23630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO28_RS23635	COG3474	cytochrome
CDO28_RS23650	COG1408	metallophosphoesterase
CDO28_RS23670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS23675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO28_RS23680	COG2080	2 iron, 2 sulfur cluster binding
CDO28_RS23685	COG0667	Aldo Keto reductase
CDO28_RS23690	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS23695	COG3386	PFAM SMP-30 Gluconolaconase
CDO28_RS23750	COG0667	Aldo Keto reductase
CDO28_RS23830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS23840	COG2226	methyltransferase
CDO28_RS23855	COG0604	alcohol dehydrogenase
CDO28_RS23860	COG0673	inositol 2-dehydrogenase activity
CDO28_RS23870	COG2169	Transcriptional regulator
CDO28_RS23885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO28_RS23925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO28_RS23935	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO28_RS23945	COG2223	nitrite transmembrane transporter activity
CDO28_RS23955	COG0583	DNA-binding transcription factor activity
CDO28_RS24015	COG0583	DNA-binding transcription factor activity
CDO28_RS24020	COG0667	Aldo Keto reductase
CDO28_RS24045	COG0583	DNA-binding transcription factor activity
CDO28_RS24060	COG3005	denitrification pathway
CDO28_RS24085	COG4459	periplasmic nitrate reductase
CDO28_RS24090	COG1309	transcriptional regulator
CDO28_RS24095	COG2814	Major facilitator Superfamily
CDO28_RS24100	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CDO28_RS24105	COG2948	multi-organism process
CDO28_RS24110	COG3504	Conjugal transfer protein
CDO28_RS24115	COG3736	Type IV secretory pathway, component VirB8
CDO28_RS24125	COG3704	protein secretion by the type IV secretion system
CDO28_RS24140	COG3451	type IV secretory pathway VirB4
CDO28_RS24145	COG3702	type iv secretory pathway
CDO28_RS24150	COG3838	Conjugal transfer protein Trbc
CDO28_RS24185	COG0477	Major facilitator Superfamily
CDO28_RS24190	COG0024	Methionine aminopeptidase
CDO28_RS24200	COG5564	TIM-barrel signal transduction protein
CDO28_RS24220	COG1175	transmembrane transport
CDO28_RS24235	COG3842	ATPase activity
CDO28_RS24240	COG3842	ATPase activity
CDO28_RS24245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO28_RS24255	COG4948	Mandelate Racemase Muconate Lactonizing
CDO28_RS24260	COG1082	Xylose isomerase domain protein TIM barrel
CDO28_RS24265	COG1082	Xylose isomerase domain protein TIM barrel
CDO28_RS24290	COG0395	ABC-type sugar transport system, permease component
CDO28_RS24295	COG1175	transmembrane transport
CDO28_RS24325	COG4608	Belongs to the ABC transporter superfamily
CDO28_RS24330	COG0444	Belongs to the ABC transporter superfamily
CDO28_RS24335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS24340	COG0601	transmembrane transport
CDO28_RS24350	COG0154	amidase activity
CDO28_RS24360	COG0747	negative chemotaxis
CDO28_RS24385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDO28_RS24390	COG2086	electron transfer activity
CDO28_RS24410	COG1960	acyl-CoA dehydrogenase activity
CDO28_RS24425	COG1024	Enoyl-CoA hydratase
CDO28_RS24435	COG0656	L-ascorbic acid biosynthetic process
CDO28_RS24455	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS24465	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS24470	COG1129	ABC transporter
CDO28_RS24475	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS24485	COG1309	transcriptional regulator
CDO28_RS24500	COG4172	Belongs to the ABC transporter superfamily
CDO28_RS24505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS24510	COG0601	transmembrane transport
CDO28_RS24515	COG0747	negative chemotaxis
CDO28_RS24525	COG2186	Transcriptional regulator
CDO28_RS24535	COG0477	Major facilitator Superfamily
CDO28_RS24545	COG0183	Belongs to the thiolase family
CDO28_RS24575	COG4948	Mandelate Racemase Muconate Lactonizing
CDO28_RS24600	COG1335	isochorismatase
CDO28_RS24605	COG0006	proline dipeptidase activity
CDO28_RS24615	COG5598	trimethylamine methyltransferase
CDO28_RS24660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO28_RS24665	COG0625	glutathione transferase activity
CDO28_RS24685	COG1802	Transcriptional regulator
CDO28_RS24695	COG3845	ABC transporter
CDO28_RS24700	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS24705	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS24775	COG0651	ATP synthesis coupled electron transport
CDO28_RS24785	COG0651	ATP synthesis coupled electron transport
CDO28_RS24795	COG0839	Belongs to the complex I subunit 6 family
CDO28_RS24800	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO28_RS24805	COG5001	Diguanylate cyclase
CDO28_RS24825	COG0840	transmembrane signaling receptor activity
CDO28_RS24830	COG2198	Histidine kinase
CDO28_RS24830	COG0643	Histidine kinase
CDO28_RS24865	COG0489	protein tyrosine kinase activity
CDO28_RS24890	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CDO28_RS24890	COG3264	Mechanosensitive ion channel
CDO28_RS24935	COG3177	Filamentation induced by cAMP protein fic
CDO28_RS24940	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO28_RS24940	COG1672	PFAM Archaeal ATPase
CDO28_RS24945	COG0723	plastoquinol--plastocyanin reductase activity
CDO28_RS24970	COG4651	solute:proton antiporter activity
CDO28_RS24970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO28_RS24980	COG1902	pentaerythritol trinitrate reductase activity
CDO28_RS25005	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS25015	COG0583	DNA-binding transcription factor activity
CDO28_RS25105	COG0628	permease
CDO28_RS25145	COG3119	arylsulfatase activity
CDO28_RS25150	COG4191	Histidine kinase
CDO28_RS25235	COG2252	PERMEase
CDO28_RS25245	COG0583	DNA-binding transcription factor activity
CDO28_RS25255	COG1335	isochorismatase
CDO28_RS25265	COG1309	transcriptional regulator
CDO28_RS25300	COG0583	DNA-binding transcription factor activity
CDO28_RS25325	COG1120	ATPase activity
CDO28_RS25330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO28_RS25335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO28_RS25365	COG1177	transmembrane transport
CDO28_RS25370	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO28_RS25375	COG3842	ATPase activity
CDO28_RS25385	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS25390	COG1802	Transcriptional regulator
CDO28_RS25400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO28_RS25465	COG0583	DNA-binding transcription factor activity
CDO28_RS25470	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO28_RS25470	COG1672	PFAM Archaeal ATPase
CDO28_RS25550	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDO28_RS25555	COG2814	Major facilitator Superfamily
CDO28_RS25565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CDO28_RS25575	COG1335	isochorismatase
CDO28_RS25585	COG2207	Transcriptional regulator
CDO28_RS25630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO28_RS25640	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS25645	COG0473	3-isopropylmalate dehydrogenase activity
CDO28_RS25655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS25665	COG0454	-acetyltransferase
CDO28_RS25685	COG0601	transmembrane transport
CDO28_RS25690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS25700	COG1522	sequence-specific DNA binding
CDO28_RS25720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO28_RS25765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO28_RS25770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO28_RS25775	COG1120	ATPase activity
CDO28_RS25785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CDO28_RS25815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDO28_RS25820	COG1280	lysine exporter protein (LysE YggA)
CDO28_RS25860	COG3278	Belongs to the heme-copper respiratory oxidase family
CDO28_RS25875	COG0459	protein refolding
CDO28_RS25880	COG0156	8-amino-7-oxononanoate synthase activity
CDO28_RS25885	COG1999	signal sequence binding
CDO28_RS25910	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO28_RS25930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO28_RS25940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO28_RS25955	COG1309	transcriptional regulator
CDO28_RS25965	COG0492	ferredoxin-NADP+ reductase activity
CDO28_RS25970	COG0583	DNA-binding transcription factor activity
CDO28_RS25985	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDO28_RS26000	COG3285	dna ligase
CDO28_RS26000	COG1793	dna ligase
CDO28_RS26025	COG1396	sequence-specific DNA binding
CDO28_RS26030	COG1525	nuclease
CDO28_RS26070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO28_RS26095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDO28_RS26110	COG0456	acetyltransferase
CDO28_RS26120	COG0165	Argininosuccinate lyase
CDO28_RS26140	COG2079	MmgE PrpD family protein
CDO28_RS26160	COG1414	Transcriptional regulator
CDO28_RS26175	COG0395	ABC-type sugar transport system, permease component
CDO28_RS26180	COG3842	ATPase activity
CDO28_RS26185	COG4948	Mandelate Racemase Muconate Lactonizing
CDO28_RS26190	COG3254	rhamnose metabolic process
CDO28_RS26205	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS26210	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO28_RS26215	COG4948	Mandelate Racemase Muconate Lactonizing
CDO28_RS26220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO28_RS26225	COG3707	response regulator
CDO28_RS26235	COG1396	sequence-specific DNA binding
CDO28_RS26245	COG3265	gluconokinase activity
CDO28_RS26255	COG1960	acyl-CoA dehydrogenase activity
CDO28_RS26260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO28_RS26295	COG0277	FAD linked oxidase domain protein
CDO28_RS26300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO28_RS26305	COG4208	sulfate ABC transporter
CDO28_RS26315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDO28_RS26330	COG0765	amino acid transport
CDO28_RS26335	COG0765	amino acid transport
CDO28_RS26345	COG0251	oxidation-reduction process
CDO28_RS26355	COG3842	ATPase activity
CDO28_RS26360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO28_RS26390	COG1940	carbohydrate kinase activity
CDO28_RS26390	COG1846	Transcriptional regulator
CDO28_RS26395	COG0175	sulfate reduction
CDO28_RS26400	COG2895	sulfate adenylyltransferase (ATP) activity
CDO28_RS26400	COG0529	Catalyzes the synthesis of activated sulfate
CDO28_RS26415	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO28_RS26420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS26455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO28_RS26485	COG0297	glycogen (starch) synthase activity
CDO28_RS26500	COG1596	polysaccharide export
CDO28_RS26505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDO28_RS26515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDO28_RS26525	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS26530	COG0668	transmembrane transport
CDO28_RS26575	COG0747	negative chemotaxis
CDO28_RS26580	COG0601	transmembrane transport
CDO28_RS26585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS26610	COG1132	(ABC) transporter
CDO28_RS26615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO28_RS26615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO28_RS26625	COG1609	Transcriptional regulator
CDO28_RS26635	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO28_RS26640	COG1177	transmembrane transport
CDO28_RS26645	COG3842	ATPase activity
CDO28_RS26655	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO28_RS26660	COG1473	amidohydrolase
CDO28_RS26665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDO28_RS26670	COG2252	PERMEase
CDO28_RS26680	COG4266	Belongs to the allantoicase family
CDO28_RS26685	COG3195	allantoin biosynthetic process
CDO28_RS26685	COG3648	Uricase
CDO28_RS26690	COG2351	hydroxyisourate hydrolase activity
CDO28_RS26700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS26710	COG1733	regulation of RNA biosynthetic process
CDO28_RS26730	COG0402	S-adenosylhomocysteine deaminase activity
CDO28_RS26735	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO28_RS26740	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO28_RS26750	COG4953	penicillin-binding protein 1C
CDO28_RS26760	COG1349	DNA-binding transcription factor activity
CDO28_RS26765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDO28_RS26770	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS26790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO28_RS26795	COG1732	Glycine betaine
CDO28_RS26800	COG1174	glycine betaine transport
CDO28_RS26805	COG1125	glycine betaine transport
CDO28_RS26810	COG1174	glycine betaine transport
CDO28_RS26815	COG0673	inositol 2-dehydrogenase activity
CDO28_RS26825	COG0395	ABC-type sugar transport system, permease component
CDO28_RS26835	COG3842	ATPase activity
CDO28_RS26860	COG0251	oxidation-reduction process
CDO28_RS26865	COG1737	Transcriptional regulator
CDO28_RS26890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CDO28_RS26900	COG2986	histidine ammonia-lyase
CDO28_RS26905	COG1228	amidohydrolase
CDO28_RS26910	COG3344	reverse transcriptase
CDO28_RS26915	COG2814	Major facilitator Superfamily
CDO28_RS26920	COG0640	Transcriptional regulator
CDO28_RS26925	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CDO28_RS26930	COG3454	Phosphonate metabolism
CDO28_RS26935	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CDO28_RS26945	COG3639	organic phosphonate transmembrane transporter activity
CDO28_RS26950	COG3639	organic phosphonate transmembrane transporter activity
CDO28_RS26960	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CDO28_RS26980	COG1960	acyl-CoA dehydrogenase activity
CDO28_RS26990	COG0326	Molecular chaperone. Has ATPase activity
CDO28_RS26995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDO28_RS27000	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS27005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO28_RS27015	COG2755	lipolytic protein G-D-S-L family
CDO28_RS27015	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO28_RS27020	COG1216	Glycosyl transferase, family 2
CDO28_RS27030	COG1132	(ABC) transporter
CDO28_RS27040	COG4166	transmembrane transport
CDO28_RS27045	COG0601	transmembrane transport
CDO28_RS27050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS27055	COG4172	Belongs to the ABC transporter superfamily
CDO28_RS27070	COG0346	lactoylglutathione lyase activity
CDO28_RS27085	COG0842	Transport permease protein
CDO28_RS27090	COG0842	Transport permease protein
CDO28_RS27095	COG1131	(ABC) transporter
CDO28_RS27100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO28_RS27110	COG2205	protein histidine kinase activity
CDO28_RS27115	COG0745	RESPONSE REGULATOR receiver
CDO28_RS27120	COG2194	sulfuric ester hydrolase activity
CDO28_RS27135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDO28_RS27140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO28_RS27170	COG0297	glycogen (starch) synthase activity
CDO28_RS27190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO28_RS27200	COG1846	Transcriptional regulator
CDO28_RS27240	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CDO28_RS27250	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDO28_RS27265	COG3237	CsbD-like
CDO28_RS27290	COG0628	permease
CDO28_RS27300	COG2080	2 iron, 2 sulfur cluster binding
CDO28_RS27305	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO28_RS27310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS27320	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS27325	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS27330	COG1129	ABC transporter
CDO28_RS27335	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS27340	COG1609	Transcriptional regulator
CDO28_RS27350	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS27355	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CDO28_RS27360	COG2186	Transcriptional regulator
CDO28_RS27375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS27380	COG1904	glucuronate isomerase
CDO28_RS27385	COG0673	inositol 2-dehydrogenase activity
CDO28_RS27390	COG1295	ribonuclease BN
CDO28_RS27420	COG2323	membrane
CDO28_RS27430	COG1295	ribonuclease BN
CDO28_RS27460	COG2010	Cytochrome c
CDO28_RS27460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO28_RS27470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO28_RS27480	COG1609	Transcriptional regulator
CDO28_RS27485	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CDO28_RS27490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO28_RS27495	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS27500	COG1129	ABC transporter
CDO28_RS27505	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS27520	COG3485	protocatechuate 3,4-dioxygenase
CDO28_RS27535	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS27540	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CDO28_RS27545	COG2207	Transcriptional regulator
CDO28_RS27550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO28_RS27555	COG4521	taurine ABC transporter
CDO28_RS27560	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CDO28_RS27565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO28_RS27580	COG0028	Belongs to the TPP enzyme family
CDO28_RS27585	COG2855	membrane
CDO28_RS27595	COG1349	DNA-binding transcription factor activity
CDO28_RS27615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO28_RS27625	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS27635	COG1840	ABC-type Fe3 transport system, periplasmic component
CDO28_RS27640	COG3842	ATPase activity
CDO28_RS27665	COG3275	phosphorelay sensor kinase activity
CDO28_RS27680	COG2897	thiosulfate sulfurtransferase activity
CDO28_RS27710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO28_RS27710	COG0475	glutathione-regulated potassium exporter activity
CDO28_RS27715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS27720	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO28_RS27725	COG2080	2 iron, 2 sulfur cluster binding
CDO28_RS27735	COG2205	protein histidine kinase activity
CDO28_RS27765	COG0459	protein refolding
CDO28_RS27770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO28_RS27775	COG5425	PFAM Usg family protein
CDO28_RS27785	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDO28_RS27785	COG1902	pentaerythritol trinitrate reductase activity
CDO28_RS27805	COG2205	protein histidine kinase activity
CDO28_RS27815	COG0640	Transcriptional regulator
CDO28_RS27835	COG2217	Heavy metal translocating P-type atpase
CDO28_RS27840	COG0789	Transcriptional regulator
CDO28_RS27845	COG1238	metal cluster binding
CDO28_RS27875	COG0189	ligase activity
CDO28_RS27880	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS27885	COG1129	ABC transporter
CDO28_RS27890	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS27895	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS27900	COG2186	Transcriptional regulator
CDO28_RS27915	COG1175	transmembrane transport
CDO28_RS27920	COG1653	transport
CDO28_RS27930	COG0673	inositol 2-dehydrogenase activity
CDO28_RS27935	COG1609	Transcriptional regulator
CDO28_RS27955	COG0395	ABC-type sugar transport system, permease component
CDO28_RS27960	COG1175	transmembrane transport
CDO28_RS27965	COG2182	Extracellular solute-binding protein
CDO28_RS27985	COG0750	zinc metalloprotease
CDO28_RS28000	COG3409	Peptidoglycan-binding domain 1 protein
CDO28_RS28000	COG0793	Belongs to the peptidase S41A family
CDO28_RS28005	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS28010	COG1129	ABC transporter
CDO28_RS28020	COG2273	Hydrolase Family 16
CDO28_RS28020	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CDO28_RS28025	COG2202	Pas domain
CDO28_RS28025	COG3920	Histidine kinase
CDO28_RS28030	COG0784	Response regulator, receiver
CDO28_RS28055	COG0602	queuosine metabolic process
CDO28_RS28060	COG0720	synthase
CDO28_RS28065	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDO28_RS28070	COG5265	(ABC) transporter
CDO28_RS28075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDO28_RS28080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO28_RS28085	COG3307	-O-antigen
CDO28_RS28090	COG1596	polysaccharide export
CDO28_RS28095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDO28_RS28105	COG1215	transferase activity, transferring glycosyl groups
CDO28_RS28110	COG2327	Polysaccharide pyruvyl transferase
CDO28_RS28115	COG0463	Glycosyl transferase, family 2
CDO28_RS28120	COG2244	polysaccharide biosynthetic process
CDO28_RS28130	COG1525	nuclease
CDO28_RS28145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO28_RS28150	COG2273	Hydrolase Family 16
CDO28_RS28155	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS28160	COG1215	transferase activity, transferring glycosyl groups
CDO28_RS28165	COG1215	transferase activity, transferring glycosyl groups
CDO28_RS28170	COG1215	transferase activity, transferring glycosyl groups
CDO28_RS28175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO28_RS28180	COG3206	protein involved in exopolysaccharide biosynthesis
CDO28_RS28180	COG0489	protein tyrosine kinase activity
CDO28_RS28190	COG0351	phosphomethylpyrimidine kinase
CDO28_RS28195	COG0450	alkyl hydroperoxide reductase
CDO28_RS28210	COG1609	Transcriptional regulator
CDO28_RS28220	COG0395	ABC-type sugar transport system, permease component
CDO28_RS28225	COG1175	transmembrane transport
CDO28_RS28235	COG3842	ATPase activity
CDO28_RS28240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO28_RS28250	COG0765	amino acid transport
CDO28_RS28260	COG1609	Transcriptional regulator
CDO28_RS28270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS28280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS28295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO28_RS28305	COG0243	molybdopterin cofactor binding
CDO28_RS28310	COG1648	precorrin-2 dehydrogenase activity
CDO28_RS28310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO28_RS28325	COG0330	HflC and HflK could
CDO28_RS28355	COG1959	2 iron, 2 sulfur cluster binding
CDO28_RS28360	COG1160	GTP binding
CDO28_RS28380	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CDO28_RS28385	COG0477	Major facilitator Superfamily
CDO28_RS28400	COG0024	Methionine aminopeptidase
CDO28_RS28435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDO28_RS28440	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS28455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS28470	COG0583	DNA-binding transcription factor activity
CDO28_RS28480	COG0402	S-adenosylhomocysteine deaminase activity
CDO28_RS28490	COG2390	Transcriptional regulator
CDO28_RS28495	COG1069	ribulokinase activity
CDO28_RS28500	COG1063	alcohol dehydrogenase
CDO28_RS28505	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS28510	COG1129	ABC transporter
CDO28_RS28515	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS28520	COG2140	Oxalate decarboxylase
CDO28_RS28525	COG1304	FMN binding
CDO28_RS28570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO28_RS28580	COG4191	Histidine kinase
CDO28_RS28585	COG4566	intracellular signal transduction
CDO28_RS28590	COG4566	intracellular signal transduction
CDO28_RS28595	COG0583	DNA-binding transcription factor activity
CDO28_RS28600	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS28605	COG2351	hydroxyisourate hydrolase activity
CDO28_RS28615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CDO28_RS28620	COG3648	Uricase
CDO28_RS28620	COG3195	allantoin biosynthetic process
CDO28_RS28650	COG0513	Belongs to the DEAD box helicase family
CDO28_RS28680	COG2308	Evidence 4 Homologs of previously reported genes of
CDO28_RS28690	COG1305	Transglutaminase-like
CDO28_RS28700	COG0129	dihydroxy-acid dehydratase activity
CDO28_RS28705	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS28715	COG4214	carbohydrate transport
CDO28_RS28725	COG4213	ABC transporter substrate-binding protein
CDO28_RS28750	COG0673	inositol 2-dehydrogenase activity
CDO28_RS28755	COG3300	MHYT domain
CDO28_RS28755	COG5001	Diguanylate cyclase
CDO28_RS28765	COG4213	ABC transporter substrate-binding protein
CDO28_RS28770	COG4214	carbohydrate transport
CDO28_RS28775	COG1129	ABC transporter
CDO28_RS28790	COG3547	Transposase (IS116 IS110 IS902 family)
CDO28_RS28795	COG3547	Transposase (IS116 IS110 IS902 family)
CDO28_RS28855	COG3328	transposase activity
CDO28_RS28870	COG1335	isochorismatase
CDO28_RS28880	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDO28_RS28905	COG3189	MarR family transcriptional regulator
CDO28_RS28910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDO28_RS28925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDO28_RS28960	COG1129	ABC transporter
CDO28_RS28965	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS28995	COG1120	ATPase activity
CDO28_RS29000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO28_RS29010	COG2226	methyltransferase
CDO28_RS29020	COG0583	DNA-binding transcription factor activity
CDO28_RS29030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS29035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO28_RS29040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS29095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDO28_RS29100	COG1573	uracil-dna glycosylase
CDO28_RS29160	COG3842	ATPase activity
CDO28_RS29165	COG1653	transport
CDO28_RS29170	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CDO28_RS29170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDO28_RS29175	COG1486	melibiose metabolic process
CDO28_RS29180	COG2188	Transcriptional regulator
CDO28_RS29185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO28_RS29190	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CDO28_RS29230	COG0300	oxidoreductase activity
CDO28_RS29250	COG3344	reverse transcriptase
CDO28_RS29270	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CDO28_RS29310	COG0477	Major facilitator Superfamily
CDO28_RS29320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO28_RS29325	COG1845	cytochrome c oxidase, subunit III
CDO28_RS29330	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDO28_RS29335	COG3346	SURF1 family
CDO28_RS29400	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS29405	COG0297	glycogen (starch) synthase activity
CDO28_RS29425	COG1280	lysine exporter protein (LysE YggA)
CDO28_RS29430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO28_RS29465	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO28_RS29475	COG1388	LysM domain
CDO28_RS29475	COG1376	ErfK ybiS ycfS ynhG family protein
CDO28_RS29490	COG4585	Histidine kinase
CDO28_RS29495	COG2197	response regulator
CDO28_RS29505	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDO28_RS29510	COG2894	cell division
CDO28_RS29515	COG0850	regulation of cytokinetic process
CDO28_RS29525	COG0656	L-ascorbic acid biosynthetic process
CDO28_RS29535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDO28_RS29540	COG0318	PFAM AMP-dependent synthetase and ligase
CDO28_RS29550	COG0367	asparagine synthase
CDO28_RS29575	COG0667	Aldo Keto reductase
CDO28_RS29585	COG0395	ABC-type sugar transport system, permease component
CDO28_RS29590	COG1175	transmembrane transport
CDO28_RS29600	COG3842	ATPase activity
CDO28_RS29610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS29620	COG3328	transposase activity
CDO28_RS29625	COG0235	Class ii aldolase
CDO28_RS29630	COG1609	Transcriptional regulator
CDO28_RS29635	COG2084	Dehydrogenase
CDO28_RS29640	COG3622	Belongs to the hyi family
CDO28_RS29645	COG3395	kinase activity
CDO28_RS29650	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS29655	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS29680	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CDO28_RS29690	COG2084	Dehydrogenase
CDO28_RS29695	COG3622	Belongs to the hyi family
CDO28_RS29700	COG3960	tartronate-semialdehyde synthase activity
CDO28_RS29705	COG1414	Transcriptional regulator
CDO28_RS29710	COG0583	DNA-binding transcription factor activity
CDO28_RS29715	COG3257	ureidoglycine aminohydrolase activity
CDO28_RS29725	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDO28_RS29755	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS29760	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS29780	COG4187	Peptidase family M20/M25/M40
CDO28_RS29815	COG0297	glycogen (starch) synthase activity
CDO28_RS29835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO28_RS29840	COG2094	Belongs to the DNA glycosylase MPG family
CDO28_RS29845	COG2084	Dehydrogenase
CDO28_RS29860	COG1129	ABC transporter
CDO28_RS29865	COG4211	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS29880	COG1609	Transcriptional regulator
CDO28_RS29885	COG1129	ABC transporter
CDO28_RS29890	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS29950	COG0174	glutamine synthetase
CDO28_RS29960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO28_RS29965	COG1215	transferase activity, transferring glycosyl groups
CDO28_RS29970	COG0246	Mannitol dehydrogenase
CDO28_RS29975	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS29985	COG1024	Enoyl-CoA hydratase
CDO28_RS29990	COG1960	acyl-CoA dehydrogenase activity
CDO28_RS29995	COG3800	Transcriptional regulator
CDO28_RS29995	COG1396	sequence-specific DNA binding
CDO28_RS30000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO28_RS30005	COG4770	biotin carboxylase activity
CDO28_RS30010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDO28_RS30010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDO28_RS30015	COG2188	Transcriptional regulator
CDO28_RS30020	COG3624	Phosphonate C-P lyase system protein PhnG
CDO28_RS30025	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CDO28_RS30030	COG3626	phosphonate metabolism
CDO28_RS30035	COG3627	carbon phosphorus lyase activity
CDO28_RS30040	COG4107	phosphonate C-P lyase system protein PhnK
CDO28_RS30045	COG4778	phosphonate C-P lyase system protein PhnL
CDO28_RS30055	COG2376	Dihydroxyacetone kinase
CDO28_RS30080	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO28_RS30085	COG1802	Transcriptional regulator
CDO28_RS30105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDO28_RS30110	COG0411	ABC transporter
CDO28_RS30125	COG0683	leucine binding
CDO28_RS30135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO28_RS30140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO28_RS30145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO28_RS30165	COG3485	protocatechuate 3,4-dioxygenase
CDO28_RS30170	COG3485	protocatechuate 3,4-dioxygenase
CDO28_RS30175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO28_RS30180	COG2267	carboxylic ester hydrolase activity
CDO28_RS30185	COG0583	DNA-binding transcription factor activity
CDO28_RS30205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO28_RS30215	COG1414	Transcriptional regulator
CDO28_RS30220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDO28_RS30225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDO28_RS30230	COG0183	Belongs to the thiolase family
CDO28_RS30235	COG1254	Belongs to the acylphosphatase family
CDO28_RS30240	COG1595	DNA-templated transcription, initiation
CDO28_RS30270	COG1192	Involved in chromosome partitioning
CDO28_RS30275	COG1475	DNA binding
CDO28_RS30290	COG0411	ABC transporter
CDO28_RS30335	COG1672	PFAM Archaeal ATPase
CDO28_RS30335	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO28_RS30340	COG0784	Response regulator, receiver
CDO28_RS30340	COG5002	protein histidine kinase activity
CDO28_RS30340	COG2198	Histidine kinase
CDO28_RS30350	COG1301	dicarboxylic acid transport
CDO28_RS30355	COG4191	Histidine kinase
CDO28_RS30360	COG2204	response regulator
CDO28_RS30370	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDO28_RS30385	COG2022	thiamine diphosphate biosynthetic process
CDO28_RS30395	COG2814	Major facilitator Superfamily
CDO28_RS30410	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDO28_RS30430	COG0395	ABC-type sugar transport system, permease component
CDO28_RS30435	COG1175	transmembrane transport
CDO28_RS30455	COG0019	diaminopimelate decarboxylase activity
CDO28_RS30460	COG1024	Enoyl-CoA hydratase
CDO28_RS30460	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO28_RS30465	COG1024	Enoyl-CoA hydratase
CDO28_RS30470	COG1607	acyl-coa hydrolase
CDO28_RS30475	COG2030	dehydratase
CDO28_RS30475	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS30480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDO28_RS30485	COG2151	metal-sulfur cluster biosynthetic enzyme
CDO28_RS30490	COG3396	Phenylacetate-CoA oxygenase
CDO28_RS30495	COG3460	Phenylacetate-CoA oxygenase
CDO28_RS30500	COG3396	Phenylacetate-CoA oxygenase
CDO28_RS30515	COG1486	melibiose metabolic process
CDO28_RS30520	COG4172	Belongs to the ABC transporter superfamily
CDO28_RS30525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS30530	COG0601	transmembrane transport
CDO28_RS30535	COG0747	negative chemotaxis
CDO28_RS30540	COG1486	melibiose metabolic process
CDO28_RS30590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDO28_RS30600	COG0625	glutathione transferase activity
CDO28_RS30610	COG0753	catalase activity
CDO28_RS30615	COG1793	dna ligase
CDO28_RS30620	COG0583	DNA-binding transcription factor activity
CDO28_RS30645	COG1609	Transcriptional regulator
CDO28_RS30650	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS30655	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS30660	COG1129	ABC transporter
CDO28_RS30675	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO28_RS30680	COG0022	dehydrogenase e1 component
CDO28_RS30685	COG1522	sequence-specific DNA binding
CDO28_RS30740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO28_RS30755	COG1309	transcriptional regulator
CDO28_RS30760	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO28_RS30765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS30770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS30775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDO28_RS30790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO28_RS30795	COG0697	spore germination
CDO28_RS30815	COG1414	Transcriptional regulator
CDO28_RS30820	COG1475	DNA binding
CDO28_RS30825	COG1192	Involved in chromosome partitioning
CDO28_RS30835	COG2188	Transcriptional regulator
CDO28_RS30840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDO28_RS30870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO28_RS30875	COG1120	ATPase activity
CDO28_RS30900	COG3609	addiction module antidote protein, CC2985 family
CDO28_RS30930	COG3360	Dodecin
CDO28_RS30935	COG1115	amino acid carrier protein
CDO28_RS30940	COG0659	secondary active sulfate transmembrane transporter activity
CDO28_RS30945	COG2814	Major facilitator Superfamily
CDO28_RS30955	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS30970	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS30975	COG4585	Histidine kinase
CDO28_RS30980	COG2197	response regulator
CDO28_RS31055	COG3685	Protein conserved in bacteria
CDO28_RS31065	COG0392	lysyltransferase activity
CDO28_RS31075	COG0028	Belongs to the TPP enzyme family
CDO28_RS31100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO28_RS31105	COG0579	oxidoreductase
CDO28_RS31110	COG3284	Transcriptional regulator
CDO28_RS31125	COG1802	Transcriptional regulator
CDO28_RS31140	COG0747	negative chemotaxis
CDO28_RS31145	COG0601	transmembrane transport
CDO28_RS31150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS31165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO28_RS31170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDO28_RS31185	COG0438	transferase activity, transferring glycosyl groups
CDO28_RS31220	COG0583	DNA-binding transcription factor activity
CDO28_RS31225	COG3845	ABC transporter
CDO28_RS31230	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS31235	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS31255	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO28_RS31265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS31265	COG2080	2 iron, 2 sulfur cluster binding
CDO28_RS31270	COG0523	cobalamin synthesis protein
CDO28_RS31275	COG2233	PERMEase
CDO28_RS31285	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CDO28_RS31305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO28_RS31315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS31320	COG0601	transmembrane transport
CDO28_RS31325	COG0747	negative chemotaxis
CDO28_RS31335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDO28_RS31340	COG1454	alcohol dehydrogenase
CDO28_RS31350	COG3395	kinase activity
CDO28_RS31375	COG1609	Transcriptional regulator
CDO28_RS31380	COG1178	ABC-type Fe3 transport system permease component
CDO28_RS31385	COG3842	ATPase activity
CDO28_RS31460	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDO28_RS31465	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDO28_RS31525	COG1116	anion transmembrane transporter activity
CDO28_RS31530	COG1131	(ABC) transporter
CDO28_RS31535	COG0842	Transport permease protein
CDO28_RS31540	COG3791	Glutathione-dependent formaldehyde-activating
CDO28_RS31560	COG4451	ribulose bisphosphate carboxylase, small
CDO28_RS31565	COG1850	ribulose-bisphosphate carboxylase activity
CDO28_RS31570	COG0191	fructose-bisphosphate aldolase activity
CDO28_RS31575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO28_RS31580	COG3954	Phosphoribulokinase
CDO28_RS31585	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CDO28_RS31590	COG0583	DNA-binding transcription factor activity
CDO28_RS31600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDO28_RS31605	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CDO28_RS31610	COG0535	radical SAM domain protein
CDO28_RS31615	COG0535	radical SAM domain protein
CDO28_RS31625	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS31630	COG0583	DNA-binding transcription factor activity
CDO28_RS31640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO28_RS31640	COG0785	Cytochrome C biogenesis protein
CDO28_RS31645	COG0300	oxidoreductase activity
CDO28_RS31675	COG0596	Alpha beta hydrolase
CDO28_RS31680	COG0596	Alpha beta hydrolase
CDO28_RS31725	COG1609	Transcriptional regulator
CDO28_RS31730	COG2182	Extracellular solute-binding protein
CDO28_RS31735	COG1175	transmembrane transport
CDO28_RS31740	COG0395	ABC-type sugar transport system, permease component
CDO28_RS31750	COG3842	ATPase activity
CDO28_RS31770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS31795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO28_RS31805	COG1063	alcohol dehydrogenase
CDO28_RS31810	COG0673	inositol 2-dehydrogenase activity
CDO28_RS31820	COG1260	myo-inositol-1-phosphate synthase
CDO28_RS31860	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDO28_RS31870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO28_RS31880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CDO28_RS31900	COG0765	amino acid transport
CDO28_RS31910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO28_RS31915	COG3938	Belongs to the proline racemase family
CDO28_RS31925	COG3938	Belongs to the proline racemase family
CDO28_RS31930	COG1765	OsmC-like protein
CDO28_RS31935	COG2814	Major facilitator Superfamily
CDO28_RS31955	COG3246	L-lysine catabolic process to acetate
CDO28_RS31965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO28_RS31980	COG2072	flavoprotein involved in K transport
CDO28_RS31985	COG3842	ATPase activity
CDO28_RS31990	COG1177	transmembrane transport
CDO28_RS32020	COG0402	S-adenosylhomocysteine deaminase activity
CDO28_RS32025	COG2233	PERMEase
CDO28_RS32030	COG1609	Transcriptional regulator
CDO28_RS32040	COG2358	TRAP transporter, solute receptor (TAXI family
CDO28_RS32055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS32060	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS32060	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CDO28_RS32065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS32075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO28_RS32085	COG2133	pyrroloquinoline quinone binding
CDO28_RS32105	COG2376	Dihydroxyacetone kinase
CDO28_RS32110	COG1461	Dihydroxyacetone kinase
CDO28_RS32115	COG2376	Dihydroxyacetone kinase
CDO28_RS32125	COG1879	ABC-type sugar transport system periplasmic component
CDO28_RS32130	COG1129	ABC transporter
CDO28_RS32135	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS32150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS32170	COG1609	Transcriptional regulator
CDO28_RS32175	COG1653	transport
CDO28_RS32190	COG3842	ATPase activity
CDO28_RS32200	COG0673	inositol 2-dehydrogenase activity
CDO28_RS32245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDO28_RS32260	COG1309	transcriptional regulator
CDO28_RS32290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS32290	COG2010	Cytochrome c
CDO28_RS32300	COG2207	Transcriptional regulator
CDO28_RS32320	COG0287	Prephenate dehydrogenase
CDO28_RS32340	COG1129	ABC transporter
CDO28_RS32345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS32350	COG0673	inositol 2-dehydrogenase activity
CDO28_RS32365	COG0784	Response regulator, receiver
CDO28_RS32365	COG2205	protein histidine kinase activity
CDO28_RS32400	COG3842	ATPase activity
CDO28_RS32410	COG1840	ABC-type Fe3 transport system, periplasmic component
CDO28_RS32415	COG1609	Transcriptional regulator
CDO28_RS32420	COG1309	transcriptional regulator
CDO28_RS32435	COG1136	(ABC) transporter
CDO28_RS32440	COG0698	ribose 5-phosphate isomerase
CDO28_RS32445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS32455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS32460	COG2186	Transcriptional regulator
CDO28_RS32480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO28_RS32485	COG3842	ATPase activity
CDO28_RS32490	COG1177	transmembrane transport
CDO28_RS32495	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDO28_RS32525	COG0604	alcohol dehydrogenase
CDO28_RS32550	COG2186	Transcriptional regulator
CDO28_RS32555	COG1850	ribulose-bisphosphate carboxylase activity
CDO28_RS32565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS32570	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO28_RS32575	COG2080	2 iron, 2 sulfur cluster binding
CDO28_RS32600	COG2010	Cytochrome c
CDO28_RS32600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS32605	COG2080	2 iron, 2 sulfur cluster binding
CDO28_RS32610	COG2010	Cytochrome c
CDO28_RS32610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO28_RS32635	COG1653	transport
CDO28_RS32640	COG1175	transmembrane transport
CDO28_RS32645	COG0395	ABC-type sugar transport system, permease component
CDO28_RS32650	COG3842	ATPase activity
CDO28_RS32655	COG0625	glutathione transferase activity
CDO28_RS32660	COG1063	alcohol dehydrogenase
CDO28_RS32665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO28_RS32670	COG1012	belongs to the aldehyde dehydrogenase family
CDO28_RS32675	COG1522	sequence-specific DNA binding
CDO28_RS32680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO28_RS32685	COG1126	abc transporter atp-binding protein
CDO28_RS32695	COG0765	amino acid transport
CDO28_RS32700	COG0765	amino acid transport
CDO28_RS32705	COG3473	Maleate cis-trans isomerase
CDO28_RS32710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO28_RS32715	COG2423	ornithine cyclodeaminase activity
CDO28_RS32720	COG0006	proline dipeptidase activity
CDO28_RS32725	COG3608	succinylglutamate desuccinylase aspartoacylase
CDO28_RS32740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO28_RS32750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDO28_RS32755	COG1063	alcohol dehydrogenase
CDO28_RS32760	COG1312	Catalyzes the dehydration of D-mannonate
CDO28_RS32765	COG3300	MHYT domain
CDO28_RS32765	COG5001	Diguanylate cyclase
CDO28_RS32805	COG1309	transcriptional regulator
CDO28_RS32810	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS32860	COG1363	Peptidase, m42
CDO28_RS32875	COG0747	negative chemotaxis
CDO28_RS32880	COG0601	transmembrane transport
CDO28_RS32890	COG4608	Belongs to the ABC transporter superfamily
CDO28_RS32895	COG2188	Transcriptional regulator
CDO28_RS32900	COG0367	asparagine synthase
CDO28_RS32920	COG1129	ABC transporter
CDO28_RS32925	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS32945	COG0235	Class ii aldolase
CDO28_RS32965	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS32970	COG0583	DNA-binding transcription factor activity
CDO28_RS32990	COG1070	Carbohydrate kinase
CDO28_RS33000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CDO28_RS33005	COG0667	Aldo Keto reductase
CDO28_RS33015	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS33020	COG1129	ABC transporter
CDO28_RS33040	COG1129	ABC transporter
CDO28_RS33050	COG2186	Transcriptional regulator
CDO28_RS33055	COG4948	Mandelate Racemase Muconate Lactonizing
CDO28_RS33060	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS33070	COG2201	protein-glutamate methylesterase activity
CDO28_RS33120	COG3220	belongs to the UPF0276 family
CDO28_RS33165	COG1609	Transcriptional regulator
CDO28_RS33290	COG2832	Protein of unknown function (DUF454)
CDO28_RS33350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO28_RS33380	COG1132	(ABC) transporter
CDO28_RS33415	COG1215	transferase activity, transferring glycosyl groups
CDO28_RS33440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO28_RS33475	COG1215	transferase activity, transferring glycosyl groups
CDO28_RS33480	COG0562	UDP-galactopyranose mutase
CDO28_RS33490	COG3547	Transposase (IS116 IS110 IS902 family)
CDO28_RS33595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDO28_RS33605	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDO28_RS33610	COG1088	dTDP-glucose 4,6-dehydratase activity
CDO28_RS33615	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CDO28_RS33625	COG1596	polysaccharide export
CDO28_RS33630	COG2197	response regulator
CDO28_RS33635	COG2197	response regulator
CDO28_RS33640	COG2197	response regulator
CDO28_RS33665	COG1609	Transcriptional regulator
CDO28_RS33685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO28_RS33705	COG0110	maltose O-acetyltransferase activity
CDO28_RS33745	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDO28_RS33745	COG0517	IMP dehydrogenase activity
CDO28_RS33810	COG1696	Membrane protein involved in D-alanine export
CDO28_RS33825	COG1028	Short-chain dehydrogenase reductase Sdr
CDO28_RS33825	COG3347	Dehydrogenase
CDO28_RS33840	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO28_RS33950	COG0601	transmembrane transport
CDO28_RS33955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO28_RS33995	COG0640	Transcriptional regulator
CDO28_RS34000	COG1475	DNA binding
CDO28_RS34005	COG1192	Involved in chromosome partitioning
CDO28_RS34010	COG4227	nucleotidyltransferase activity
CDO28_RS34015	COG2184	nucleotidyltransferase activity
CDO28_RS34060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO28_RS34135	COG3706	GGDEF domain
CDO28_RS34175	COG1278	Cold shock
CDO28_RS34255	COG0741	lytic transglycosylase activity
CDO28_RS34260	COG3838	Conjugal transfer protein Trbc
CDO28_RS34270	COG3451	type IV secretory pathway VirB4
CDO28_RS34275	COG0741	lytic transglycosylase activity
CDO28_RS34310	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CDO28_RS34325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO28_RS34335	COG3547	Transposase (IS116 IS110 IS902 family)
CDO28_RS34350	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO28_RS34355	COG0667	Aldo Keto reductase
CDO28_RS34365	COG0287	Prephenate dehydrogenase
CDO28_RS34375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO28_RS34375	COG0512	Glutamine amidotransferase of anthranilate synthase
CDO28_RS34395	COG3012	SEC-C Motif Domain Protein
CDO28_RS34405	COG3436	PFAM IS66 Orf2 family protein
CDO28_RS34410	COG0582	viral genome integration into host DNA
CDO28_RS34415	COG0582	viral genome integration into host DNA
CDO28_RS34425	COG3436	PFAM IS66 Orf2 family protein
CDO28_RS34430	COG2963	transposase activity
CDO28_RS34465	COG3475	LICD family
CDO28_RS34470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDO28_RS34485	COG0842	Transport permease protein
CDO28_RS34485	COG1129	ABC transporter
CDO28_RS34495	COG3328	transposase activity
CDO28_RS34590	COG4566	intracellular signal transduction
CDO28_RS34625	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CDO28_RS34715	COG0641	radical SAM