locus-tag	class	description
F3Y30_RS00025	COG1846	Transcriptional regulator
F3Y30_RS00035	COG0523	cobalamin synthesis protein
F3Y30_RS00080	COG0583	DNA-binding transcription factor activity
F3Y30_RS00090	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F3Y30_RS00110	COG0800	Aldolase
F3Y30_RS00125	COG1054	Belongs to the UPF0176 family
F3Y30_RS00140	COG1464	Belongs to the NlpA lipoprotein family
F3Y30_RS00145	COG2011	ABC-type metal ion transport system permease component
F3Y30_RS00150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F3Y30_RS00160	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS00170	COG2115	Belongs to the xylose isomerase family
F3Y30_RS00175	COG1070	Carbohydrate kinase
F3Y30_RS00180	COG1609	Transcriptional regulator
F3Y30_RS00195	COG1309	transcriptional regulator
F3Y30_RS00200	COG1253	flavin adenine dinucleotide binding
F3Y30_RS00205	COG0386	Belongs to the glutathione peroxidase family
F3Y30_RS00210	COG3273	potassium ion transport
F3Y30_RS00210	COG0471	metal ion transport
F3Y30_RS00215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3Y30_RS00220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F3Y30_RS00235	COG1121	(ABC) transporter
F3Y30_RS00240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3Y30_RS00245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3Y30_RS00250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS00260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F3Y30_RS00280	COG0835	chemotaxis
F3Y30_RS00290	COG0840	transmembrane signaling receptor activity
F3Y30_RS00295	COG0835	chemotaxis
F3Y30_RS00300	COG0643	Histidine kinase
F3Y30_RS00300	COG2198	Histidine kinase
F3Y30_RS00320	COG1174	glycine betaine transport
F3Y30_RS00325	COG1125	glycine betaine transport
F3Y30_RS00330	COG1174	glycine betaine transport
F3Y30_RS00335	COG1732	Glycine betaine
F3Y30_RS00345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3Y30_RS00355	COG3284	Transcriptional regulator
F3Y30_RS00360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3Y30_RS00365	COG0450	alkyl hydroperoxide reductase
F3Y30_RS00385	COG3842	ATPase activity
F3Y30_RS00395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3Y30_RS00410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3Y30_RS00415	COG1116	anion transmembrane transporter activity
F3Y30_RS00415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3Y30_RS00420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3Y30_RS00475	COG3622	Belongs to the hyi family
F3Y30_RS00480	COG2084	Dehydrogenase
F3Y30_RS00485	COG1609	Transcriptional regulator
F3Y30_RS00495	COG0235	Class ii aldolase
F3Y30_RS00505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3Y30_RS00505	COG3453	Protein conserved in bacteria
F3Y30_RS00510	COG0640	Transcriptional regulator
F3Y30_RS00530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F3Y30_RS00540	COG0589	response to stress
F3Y30_RS00550	COG1959	2 iron, 2 sulfur cluster binding
F3Y30_RS00565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3Y30_RS00570	COG0583	DNA-binding transcription factor activity
F3Y30_RS00585	COG1064	alcohol dehydrogenase
F3Y30_RS00595	COG0667	Aldo Keto reductase
F3Y30_RS00600	COG4221	oxidoreductase activity
F3Y30_RS00605	COG2814	Major facilitator Superfamily
F3Y30_RS00615	COG0765	amino acid transport
F3Y30_RS00620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3Y30_RS00625	COG2011	ABC-type metal ion transport system permease component
F3Y30_RS00635	COG1464	Belongs to the NlpA lipoprotein family
F3Y30_RS00655	COG2011	ABC-type metal ion transport system permease component
F3Y30_RS00660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F3Y30_RS00670	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3Y30_RS00670	COG1672	PFAM Archaeal ATPase
F3Y30_RS00695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3Y30_RS00700	COG1414	Transcriptional regulator
F3Y30_RS00720	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS00730	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3Y30_RS00765	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS00790	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS00815	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS00825	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F3Y30_RS00840	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS00850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3Y30_RS00870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3Y30_RS00875	COG2309	aminopeptidase activity
F3Y30_RS00890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3Y30_RS00905	COG1091	dTDP-4-dehydrorhamnose reductase activity
F3Y30_RS00955	COG1846	Transcriptional regulator
F3Y30_RS00985	COG0297	glycogen (starch) synthase activity
F3Y30_RS01005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3Y30_RS01055	COG0741	lytic transglycosylase activity
F3Y30_RS01055	COG1196	nuclear chromosome segregation
F3Y30_RS01055	COG0739	heme binding
F3Y30_RS01060	COG0542	response to heat
F3Y30_RS01070	COG2890	protein-(glutamine-N5) methyltransferase activity
F3Y30_RS01075	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F3Y30_RS01080	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
F3Y30_RS01085	COG0527	aspartate kinase activity
F3Y30_RS01095	COG0583	DNA-binding transcription factor activity
F3Y30_RS01110	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS01110	COG1388	LysM domain
F3Y30_RS01115	COG2259	Doxx family
F3Y30_RS01120	COG0583	DNA-binding transcription factor activity
F3Y30_RS01155	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS01165	COG3842	ATPase activity
F3Y30_RS01170	COG3842	ATPase activity
F3Y30_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS01190	COG0604	alcohol dehydrogenase
F3Y30_RS01210	COG3383	formate dehydrogenase (NAD+) activity
F3Y30_RS01215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F3Y30_RS01235	COG0835	chemotaxis
F3Y30_RS01240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3Y30_RS01245	COG0010	Belongs to the arginase family
F3Y30_RS01265	COG0729	surface antigen
F3Y30_RS01290	COG0156	8-amino-7-oxononanoate synthase activity
F3Y30_RS01295	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F3Y30_RS01320	COG1473	amidohydrolase
F3Y30_RS01325	COG1686	Belongs to the peptidase S11 family
F3Y30_RS01330	COG0523	cobalamin synthesis protein
F3Y30_RS01340	COG3034	peptidoglycan biosynthetic process
F3Y30_RS01345	COG0825	malonyl-CoA metabolic process
F3Y30_RS01360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F3Y30_RS01365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F3Y30_RS01400	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F3Y30_RS01410	COG0287	Prephenate dehydrogenase
F3Y30_RS01415	COG2226	methyltransferase
F3Y30_RS01420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3Y30_RS01440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F3Y30_RS01465	COG2884	Cell division ATP-binding protein ftsE
F3Y30_RS01475	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
F3Y30_RS01490	COG0019	diaminopimelate decarboxylase activity
F3Y30_RS01500	COG0165	Argininosuccinate lyase
F3Y30_RS01505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3Y30_RS01510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3Y30_RS01515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3Y30_RS01520	COG4208	sulfate ABC transporter
F3Y30_RS01530	COG4150	thiosulfate binding
F3Y30_RS01535	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3Y30_RS01545	COG2086	electron transfer activity
F3Y30_RS01555	COG2096	Adenosyltransferase
F3Y30_RS01565	COG0300	oxidoreductase activity
F3Y30_RS01575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3Y30_RS01615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3Y30_RS01635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3Y30_RS01640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F3Y30_RS01650	COG0494	nUDIX hydrolase
F3Y30_RS01665	COG2226	methyltransferase
F3Y30_RS01670	COG1040	competence protein
F3Y30_RS01680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3Y30_RS01695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3Y30_RS01710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3Y30_RS01715	COG0662	Cupin 2, conserved barrel domain protein
F3Y30_RS01715	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F3Y30_RS01720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F3Y30_RS01725	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F3Y30_RS01730	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F3Y30_RS01735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F3Y30_RS01740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F3Y30_RS01760	COG4974	Belongs to the 'phage' integrase family
F3Y30_RS01780	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS01810	COG0567	Dehydrogenase, E1 component
F3Y30_RS01815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3Y30_RS01820	COG0045	succinate-CoA ligase (ADP-forming) activity
F3Y30_RS01825	COG0039	L-malate dehydrogenase activity
F3Y30_RS01830	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F3Y30_RS01835	COG2845	Protein of unknown function (DUF459)
F3Y30_RS01855	COG2009	succinate dehydrogenase
F3Y30_RS01865	COG2264	protein methyltransferase activity
F3Y30_RS01880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F3Y30_RS01885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F3Y30_RS01890	COG0181	hydroxymethylbilane synthase activity
F3Y30_RS01915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3Y30_RS01925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F3Y30_RS01935	COG1217	gtp-binding protein TYPA
F3Y30_RS01945	COG0339	signal peptide processing
F3Y30_RS02000	COG0477	Major facilitator Superfamily
F3Y30_RS02005	COG0137	argininosuccinate synthase activity
F3Y30_RS02015	COG1122	ATPase activity
F3Y30_RS02020	COG4120	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS02030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F3Y30_RS02055	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
F3Y30_RS02060	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F3Y30_RS02065	COG0625	glutathione transferase activity
F3Y30_RS02070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3Y30_RS02075	COG0142	geranyltranstransferase activity
F3Y30_RS02080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F3Y30_RS02085	COG1280	lysine exporter protein (LysE YggA)
F3Y30_RS02090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F3Y30_RS02095	COG0670	Belongs to the BI1 family
F3Y30_RS02100	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F3Y30_RS02105	COG4181	ATPase activity
F3Y30_RS02115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F3Y30_RS02130	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F3Y30_RS02135	COG1329	Transcriptional regulator
F3Y30_RS02150	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F3Y30_RS02170	COG0488	(ABC) transporter
F3Y30_RS02175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3Y30_RS02180	COG0765	amino acid transport
F3Y30_RS02185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F3Y30_RS02195	COG0656	L-ascorbic acid biosynthetic process
F3Y30_RS02205	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS02220	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F3Y30_RS02225	COG1674	ftsk spoiiie
F3Y30_RS02230	COG0004	ammonium transporteR
F3Y30_RS02235	COG0347	Belongs to the P(II) protein family
F3Y30_RS02240	COG1946	Acyl-CoA thioesterase
F3Y30_RS02245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3Y30_RS02250	COG2835	tetraacyldisaccharide 4'-kinase activity
F3Y30_RS02285	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
F3Y30_RS02290	COG0335	large ribosomal subunit rRNA binding
F3Y30_RS02300	COG0336	Belongs to the RNA methyltransferase TrmD family
F3Y30_RS02305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F3Y30_RS02310	COG0228	four-way junction DNA binding
F3Y30_RS02315	COG0287	Prephenate dehydrogenase
F3Y30_RS02315	COG1605	Chorismate mutase
F3Y30_RS02320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F3Y30_RS02335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3Y30_RS02340	COG0552	protein localization to endoplasmic reticulum
F3Y30_RS02345	COG2917	probably involved in intracellular septation
F3Y30_RS02360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3Y30_RS02370	COG4133	protoheme IX ABC transporter activity
F3Y30_RS02380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3Y30_RS02405	COG2197	response regulator
F3Y30_RS02415	COG1132	(ABC) transporter
F3Y30_RS02425	COG3459	Glycosyltransferase 36 associated
F3Y30_RS02455	COG0587	DNA-directed DNA polymerase activity
F3Y30_RS02465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS02470	COG0174	glutamine synthetase
F3Y30_RS02480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS02495	COG0436	Aminotransferase
F3Y30_RS02500	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS02505	COG0277	FAD linked oxidase domain protein
F3Y30_RS02510	COG5383	Protein conserved in bacteria
F3Y30_RS02525	COG2223	nitrite transmembrane transporter activity
F3Y30_RS02585	COG0840	transmembrane signaling receptor activity
F3Y30_RS02610	COG1596	polysaccharide export
F3Y30_RS02635	COG0438	transferase activity, transferring glycosyl groups
F3Y30_RS02645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3Y30_RS02655	COG1120	ATPase activity
F3Y30_RS02670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F3Y30_RS02675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F3Y30_RS02680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3Y30_RS02710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F3Y30_RS02715	COG0799	negative regulation of ribosome biogenesis
F3Y30_RS02720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F3Y30_RS02730	COG0793	Belongs to the peptidase S41A family
F3Y30_RS02740	COG0494	nUDIX hydrolase
F3Y30_RS02775	COG0066	3-isopropylmalate dehydratase activity
F3Y30_RS02780	COG0251	oxidation-reduction process
F3Y30_RS02785	COG0473	3-isopropylmalate dehydrogenase activity
F3Y30_RS02790	COG0671	phosphoesterase, PA-phosphatase related
F3Y30_RS02805	COG1136	(ABC) transporter
F3Y30_RS02820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3Y30_RS02830	COG0288	reversible hydration of carbon dioxide
F3Y30_RS02840	COG2902	Dehydrogenase
F3Y30_RS02850	COG0138	bifunctional purine biosynthesis protein purh
F3Y30_RS02860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F3Y30_RS02860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3Y30_RS02865	COG0501	Belongs to the peptidase M48B family
F3Y30_RS02895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F3Y30_RS02900	COG0495	leucyl-tRNA aminoacylation
F3Y30_RS02925	COG0357	Ribosomal RNA small subunit methyltransferase G
F3Y30_RS02930	COG0445	tRNA wobble uridine modification
F3Y30_RS02935	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F3Y30_RS02940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F3Y30_RS02945	COG1981	membrane
F3Y30_RS02950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F3Y30_RS02955	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
F3Y30_RS02960	COG0424	maF-like protein
F3Y30_RS02965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3Y30_RS02970	COG0237	dephospho-CoA kinase activity
F3Y30_RS02975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3Y30_RS02980	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F3Y30_RS02985	COG3030	protein affecting phage T7 exclusion by the F plasmid
F3Y30_RS02995	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F3Y30_RS03040	COG1802	Transcriptional regulator
F3Y30_RS03065	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS03070	COG1063	alcohol dehydrogenase
F3Y30_RS03075	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS03095	COG0135	phosphoribosylanthranilate isomerase activity
F3Y30_RS03100	COG0133	tryptophan synthase activity
F3Y30_RS03110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F3Y30_RS03135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3Y30_RS03140	COG3178	'Phosphotransferase
F3Y30_RS03145	COG2205	protein histidine kinase activity
F3Y30_RS03150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F3Y30_RS03160	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3Y30_RS03160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3Y30_RS03165	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
F3Y30_RS03170	COG2205	protein histidine kinase activity
F3Y30_RS03175	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS03180	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F3Y30_RS03190	COG1652	LysM domain
F3Y30_RS03200	COG1072	(Pantothenic acid kinase))
F3Y30_RS03205	COG0140	phosphoribosyl-ATP diphosphatase activity
F3Y30_RS03210	COG0107	imidazoleglycerol-phosphate synthase activity
F3Y30_RS03215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F3Y30_RS03220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3Y30_RS03230	COG0131	Imidazoleglycerol-phosphate dehydratase
F3Y30_RS03235	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F3Y30_RS03245	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F3Y30_RS03255	COG2124	cytochrome p450
F3Y30_RS03270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F3Y30_RS03275	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS03285	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
F3Y30_RS03295	COG1643	Atp-dependent helicase
F3Y30_RS03345	COG1959	2 iron, 2 sulfur cluster binding
F3Y30_RS03360	COG3273	potassium ion transport
F3Y30_RS03360	COG0471	metal ion transport
F3Y30_RS03370	COG1082	Xylose isomerase domain protein TIM barrel
F3Y30_RS03375	COG1082	Xylose isomerase domain protein TIM barrel
F3Y30_RS03380	COG4948	Mandelate Racemase Muconate Lactonizing
F3Y30_RS03395	COG1063	alcohol dehydrogenase
F3Y30_RS03400	COG3257	ureidoglycine aminohydrolase activity
F3Y30_RS03425	COG3842	ATPase activity
F3Y30_RS03435	COG1177	transmembrane transport
F3Y30_RS03440	COG1335	isochorismatase
F3Y30_RS03450	COG1349	DNA-binding transcription factor activity
F3Y30_RS03460	COG3842	ATPase activity
F3Y30_RS03465	COG3842	ATPase activity
F3Y30_RS03480	COG1175	transmembrane transport
F3Y30_RS03530	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F3Y30_RS03540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3Y30_RS03570	COG1132	(ABC) transporter
F3Y30_RS03575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3Y30_RS03575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3Y30_RS03585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3Y30_RS03605	COG0443	Heat shock 70 kDa protein
F3Y30_RS03615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3Y30_RS03625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F3Y30_RS03640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3Y30_RS03650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3Y30_RS03655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F3Y30_RS03660	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F3Y30_RS03670	COG0840	transmembrane signaling receptor activity
F3Y30_RS03685	COG1309	transcriptional regulator
F3Y30_RS03700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3Y30_RS03705	COG0588	phosphoglycerate mutase activity
F3Y30_RS03710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F3Y30_RS03715	COG1132	(ABC) transporter
F3Y30_RS03720	COG0837	glucose binding
F3Y30_RS03725	COG1803	Methylglyoxal synthase
F3Y30_RS03730	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
F3Y30_RS03735	COG4166	transmembrane transport
F3Y30_RS03740	COG4174	ABC transporter (Permease)
F3Y30_RS03745	COG4239	(ABC) transporter, permease
F3Y30_RS03750	COG4172	Belongs to the ABC transporter superfamily
F3Y30_RS03760	COG0791	NLP P60 protein
F3Y30_RS03770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F3Y30_RS03805	COG4964	Belongs to the GSP D family
F3Y30_RS03840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F3Y30_RS03845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F3Y30_RS03850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F3Y30_RS03860	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F3Y30_RS03865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F3Y30_RS03870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F3Y30_RS03880	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS03890	COG3845	ABC transporter
F3Y30_RS03895	COG2900	Belongs to the SlyX family
F3Y30_RS03900	COG1744	ABC transporter substrate-binding protein PnrA-like
F3Y30_RS03905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3Y30_RS03950	COG0628	permease
F3Y30_RS03970	COG3047	cAMP biosynthetic process
F3Y30_RS03970	COG2885	chlorophyll binding
F3Y30_RS04005	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3Y30_RS04010	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS04030	COG0582	viral genome integration into host DNA
F3Y30_RS04035	COG0625	glutathione transferase activity
F3Y30_RS04060	COG1960	acyl-CoA dehydrogenase activity
F3Y30_RS04065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3Y30_RS04090	COG4953	penicillin-binding protein 1C
F3Y30_RS04095	COG2373	Large extracellular alpha-helical protein
F3Y30_RS04105	COG3474	cytochrome
F3Y30_RS04110	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F3Y30_RS04115	COG0077	Prephenate dehydratase
F3Y30_RS04115	COG1605	Chorismate mutase
F3Y30_RS04120	COG2816	NAD+ diphosphatase activity
F3Y30_RS04135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F3Y30_RS04140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F3Y30_RS04145	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3Y30_RS04155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F3Y30_RS04160	COG2951	lytic endotransglycosylase activity
F3Y30_RS04165	COG2814	Major facilitator Superfamily
F3Y30_RS04170	COG0779	Required for maturation of 30S ribosomal subunits
F3Y30_RS04190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F3Y30_RS04195	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F3Y30_RS04200	COG3920	Histidine kinase
F3Y30_RS04205	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F3Y30_RS04210	COG1185	polyribonucleotide nucleotidyltransferase activity
F3Y30_RS04220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3Y30_RS04230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3Y30_RS04275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3Y30_RS04280	COG1278	Cold shock
F3Y30_RS04300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F3Y30_RS04305	COG0539	negative regulation of cytoplasmic translation
F3Y30_RS04345	COG1132	(ABC) transporter
F3Y30_RS04350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3Y30_RS04350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3Y30_RS04355	COG1234	tRNA 3'-trailer cleavage
F3Y30_RS04360	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3Y30_RS04400	COG0601	transmembrane transport
F3Y30_RS04405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3Y30_RS04420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F3Y30_RS04455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3Y30_RS04460	COG0418	dihydroorotase activity
F3Y30_RS04485	COG1940	carbohydrate kinase activity
F3Y30_RS04500	COG0583	DNA-binding transcription factor activity
F3Y30_RS04510	COG0481	GTPase activity
F3Y30_RS04530	COG2885	chlorophyll binding
F3Y30_RS04535	COG5006	permease, DMT superfamily
F3Y30_RS04545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3Y30_RS04575	COG0667	Aldo Keto reductase
F3Y30_RS04590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F3Y30_RS04595	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F3Y30_RS04600	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F3Y30_RS04605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F3Y30_RS04640	COG1846	Transcriptional regulator
F3Y30_RS04645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3Y30_RS04650	COG2309	aminopeptidase activity
F3Y30_RS04670	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3Y30_RS04670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3Y30_RS04675	COG4311	Sarcosine oxidase, delta subunit
F3Y30_RS04680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS04685	COG4977	sequence-specific DNA binding
F3Y30_RS04695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3Y30_RS04700	COG2218	PFAM glutamate synthase alpha subunit domain protein
F3Y30_RS04705	COG0069	glutamate synthase activity
F3Y30_RS04710	COG0174	glutamine synthetase
F3Y30_RS04720	COG0183	Belongs to the thiolase family
F3Y30_RS04725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3Y30_RS04730	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F3Y30_RS04735	COG1414	Transcriptional regulator
F3Y30_RS04740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3Y30_RS04755	COG0583	DNA-binding transcription factor activity
F3Y30_RS04760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F3Y30_RS04765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3Y30_RS04770	COG3485	protocatechuate 3,4-dioxygenase
F3Y30_RS04775	COG3485	protocatechuate 3,4-dioxygenase
F3Y30_RS04780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3Y30_RS04785	COG0683	leucine binding
F3Y30_RS04810	COG1393	Belongs to the ArsC family
F3Y30_RS04815	COG1448	Aminotransferase
F3Y30_RS04840	COG0519	Catalyzes the synthesis of GMP from XMP
F3Y30_RS04840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F3Y30_RS04855	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
F3Y30_RS04895	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3Y30_RS04905	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F3Y30_RS04915	COG1968	undecaprenyl-diphosphatase activity
F3Y30_RS04935	COG0284	orotidine-5'-phosphate decarboxylase activity
F3Y30_RS04955	COG0792	nuclease activity
F3Y30_RS04970	COG0189	ligase activity
F3Y30_RS04980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3Y30_RS05000	COG1522	sequence-specific DNA binding
F3Y30_RS05010	COG0756	dUTP diphosphatase activity
F3Y30_RS05015	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F3Y30_RS05065	COG1741	Belongs to the pirin family
F3Y30_RS05090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F3Y30_RS05095	COG2226	methyltransferase
F3Y30_RS05100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F3Y30_RS05105	COG0268	Binds directly to 16S ribosomal RNA
F3Y30_RS05110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F3Y30_RS05115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3Y30_RS05120	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F3Y30_RS05130	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F3Y30_RS05140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F3Y30_RS05145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3Y30_RS05150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3Y30_RS05155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F3Y30_RS05160	COG1137	ATPase activity
F3Y30_RS05165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F3Y30_RS05180	COG0776	regulation of translation
F3Y30_RS05195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F3Y30_RS05195	COG0116	Belongs to the methyltransferase superfamily
F3Y30_RS05200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3Y30_RS05205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F3Y30_RS05220	COG0281	malic enzyme
F3Y30_RS05220	COG0280	phosphate acetyltransferase
F3Y30_RS05225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F3Y30_RS05230	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F3Y30_RS05245	COG0180	Tryptophanyl-tRNA synthetase
F3Y30_RS05255	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F3Y30_RS05260	COG1214	PFAM Peptidase M22, glycoprotease
F3Y30_RS05280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3Y30_RS05285	COG1702	phosphate starvation-inducible protein PhoH
F3Y30_RS05290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F3Y30_RS05305	COG1396	sequence-specific DNA binding
F3Y30_RS05310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F3Y30_RS05315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F3Y30_RS05325	COG0071	Belongs to the small heat shock protein (HSP20) family
F3Y30_RS05340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3Y30_RS05350	COG0242	peptide deformylase activity
F3Y30_RS05355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F3Y30_RS05360	COG0101	tRNA pseudouridine synthase activity
F3Y30_RS05380	COG2171	N-acyltransferase activity
F3Y30_RS05405	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
F3Y30_RS05410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F3Y30_RS05430	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F3Y30_RS05440	COG0706	membrane insertase activity
F3Y30_RS05445	COG0594	ribonuclease P activity
F3Y30_RS05450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F3Y30_RS05460	COG5002	protein histidine kinase activity
F3Y30_RS05480	COG0625	glutathione transferase activity
F3Y30_RS05515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F3Y30_RS05520	COG3938	Belongs to the proline racemase family
F3Y30_RS05540	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3Y30_RS05555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F3Y30_RS05570	COG0318	PFAM AMP-dependent synthetase and ligase
F3Y30_RS05575	COG0628	permease
F3Y30_RS05625	COG2326	polyphosphate kinase activity
F3Y30_RS05630	COG5002	protein histidine kinase activity
F3Y30_RS05640	COG0573	inorganic phosphate transmembrane transporter activity
F3Y30_RS05650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3Y30_RS05655	COG0704	Plays a role in the regulation of phosphate uptake
F3Y30_RS05660	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS05670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3Y30_RS05675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F3Y30_RS05685	COG2967	ApaG domain
F3Y30_RS05710	COG3800	Transcriptional regulator
F3Y30_RS05710	COG1396	sequence-specific DNA binding
F3Y30_RS05725	COG4770	biotin carboxylase activity
F3Y30_RS05730	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F3Y30_RS05730	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F3Y30_RS05740	COG1120	ATPase activity
F3Y30_RS05745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3Y30_RS05795	COG0697	spore germination
F3Y30_RS05810	COG2204	response regulator
F3Y30_RS05815	COG1621	beta-fructofuranosidase activity
F3Y30_RS05840	COG2814	Major facilitator Superfamily
F3Y30_RS05845	COG1024	Enoyl-CoA hydratase
F3Y30_RS05845	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3Y30_RS05850	COG0183	Belongs to the thiolase family
F3Y30_RS05855	COG1960	acyl-CoA dehydrogenase activity
F3Y30_RS05865	COG0730	response to heat
F3Y30_RS05890	COG1201	RNA secondary structure unwinding
F3Y30_RS05915	COG0534	Mate efflux family protein
F3Y30_RS05920	COG0167	dihydroorotate dehydrogenase activity
F3Y30_RS05940	COG2198	Histidine kinase
F3Y30_RS05940	COG0784	Response regulator, receiver
F3Y30_RS05940	COG2205	protein histidine kinase activity
F3Y30_RS05945	COG1970	mechanosensitive ion channel activity
F3Y30_RS05950	COG0436	Aminotransferase
F3Y30_RS05960	COG0287	Prephenate dehydrogenase
F3Y30_RS05960	COG1605	Chorismate mutase
F3Y30_RS05970	COG1473	amidohydrolase
F3Y30_RS05980	COG4215	(ABC) transporter
F3Y30_RS05985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3Y30_RS06000	COG1309	transcriptional regulator
F3Y30_RS06015	COG0287	Prephenate dehydrogenase
F3Y30_RS06030	COG1129	ABC transporter
F3Y30_RS06035	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS06040	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS06065	COG1850	ribulose-bisphosphate carboxylase activity
F3Y30_RS06085	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS06115	COG5002	protein histidine kinase activity
F3Y30_RS06120	COG0714	Associated with various cellular activities
F3Y30_RS06155	COG1309	transcriptional regulator
F3Y30_RS06160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3Y30_RS06165	COG1131	(ABC) transporter
F3Y30_RS06170	COG0842	Transport permease protein
F3Y30_RS06175	COG0842	Transport permease protein
F3Y30_RS06200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F3Y30_RS06205	COG5328	Belongs to the UPF0262 family
F3Y30_RS06215	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F3Y30_RS06220	COG0424	maF-like protein
F3Y30_RS06225	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F3Y30_RS06250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F3Y30_RS06255	COG4952	isomerase
F3Y30_RS06260	COG3347	Dehydrogenase
F3Y30_RS06260	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS06265	COG1349	DNA-binding transcription factor activity
F3Y30_RS06275	COG1129	ABC transporter
F3Y30_RS06280	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS06290	COG3254	rhamnose metabolic process
F3Y30_RS06300	COG0840	transmembrane signaling receptor activity
F3Y30_RS06310	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS06320	COG0835	chemotaxis
F3Y30_RS06325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F3Y30_RS06330	COG2201	protein-glutamate methylesterase activity
F3Y30_RS06335	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS06340	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
F3Y30_RS06350	COG1766	The M ring may be actively involved in energy transduction
F3Y30_RS06365	COG2771	luxR family
F3Y30_RS06380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3Y30_RS06385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3Y30_RS06390	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3Y30_RS06395	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3Y30_RS06400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F3Y30_RS06410	COG4786	Flagellar basal body rod
F3Y30_RS06415	COG1157	protein secretion by the type III secretion system
F3Y30_RS06425	COG1815	bacterial-type flagellum-dependent cell motility
F3Y30_RS06430	COG1558	bacterial-type flagellum-dependent cell motility
F3Y30_RS06435	COG1677	Flagellar hook-basal body complex protein FliE
F3Y30_RS06440	COG4786	Flagellar basal body rod
F3Y30_RS06445	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
F3Y30_RS06450	COG1706	bacterial-type flagellum-dependent cell motility
F3Y30_RS06460	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
F3Y30_RS06470	COG1338	Plays a role in the flagellum-specific transport system
F3Y30_RS06480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3Y30_RS06485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3Y30_RS06490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3Y30_RS06525	COG1749	Flagellar hook protein flgE
F3Y30_RS06545	COG5443	negative regulation of bacterial-type flagellum assembly
F3Y30_RS06555	COG4794	Type iii secretion
F3Y30_RS06560	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3Y30_RS06595	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
F3Y30_RS06600	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F3Y30_RS06605	COG1609	Transcriptional regulator
F3Y30_RS06610	COG1653	transport
F3Y30_RS06615	COG1175	transmembrane transport
F3Y30_RS06620	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS06625	COG0366	Alpha amylase catalytic
F3Y30_RS06630	COG3842	ATPase activity
F3Y30_RS06640	COG0129	dihydroxy-acid dehydratase activity
F3Y30_RS06645	COG0363	glucosamine-6-phosphate deaminase activity
F3Y30_RS06650	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3Y30_RS06665	COG2081	HI0933 family
F3Y30_RS06675	COG0840	transmembrane signaling receptor activity
F3Y30_RS06675	COG2972	Histidine kinase
F3Y30_RS06680	COG0840	transmembrane signaling receptor activity
F3Y30_RS06680	COG2972	Histidine kinase
F3Y30_RS06695	COG2224	Isocitrate lyase
F3Y30_RS06710	COG3842	ATPase activity
F3Y30_RS06715	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS06720	COG1177	transmembrane transport
F3Y30_RS06735	COG1178	ABC-type Fe3 transport system permease component
F3Y30_RS06740	COG2205	protein histidine kinase activity
F3Y30_RS06785	COG1840	ABC-type Fe3 transport system, periplasmic component
F3Y30_RS06790	COG1959	2 iron, 2 sulfur cluster binding
F3Y30_RS06800	COG2197	response regulator
F3Y30_RS06805	COG0747	negative chemotaxis
F3Y30_RS06810	COG0601	transmembrane transport
F3Y30_RS06815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3Y30_RS06820	COG0444	Belongs to the ABC transporter superfamily
F3Y30_RS06825	COG4608	Belongs to the ABC transporter superfamily
F3Y30_RS06830	COG3265	gluconokinase activity
F3Y30_RS06840	COG1175	transmembrane transport
F3Y30_RS06845	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS06870	COG1461	Dihydroxyacetone kinase
F3Y30_RS06895	COG2376	Dihydroxyacetone kinase
F3Y30_RS06900	COG0251	oxidation-reduction process
F3Y30_RS06905	COG0784	Response regulator, receiver
F3Y30_RS06940	COG2188	Transcriptional regulator
F3Y30_RS06945	COG3624	Phosphonate C-P lyase system protein PhnG
F3Y30_RS06950	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F3Y30_RS06955	COG3626	phosphonate metabolism
F3Y30_RS06960	COG3627	carbon phosphorus lyase activity
F3Y30_RS06965	COG4107	phosphonate C-P lyase system protein PhnK
F3Y30_RS06970	COG4778	phosphonate C-P lyase system protein PhnL
F3Y30_RS06980	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F3Y30_RS06990	COG3639	organic phosphonate transmembrane transporter activity
F3Y30_RS07000	COG3454	Phosphonate metabolism
F3Y30_RS07005	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3Y30_RS07045	COG3842	ATPase activity
F3Y30_RS07055	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS07065	COG0583	DNA-binding transcription factor activity
F3Y30_RS07080	COG0667	Aldo Keto reductase
F3Y30_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS07115	COG1802	Transcriptional regulator
F3Y30_RS07120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3Y30_RS07135	COG4176	ABC-type proline glycine betaine transport system permease component
F3Y30_RS07140	COG4175	Glycine betaine
F3Y30_RS07145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3Y30_RS07165	COG4977	sequence-specific DNA binding
F3Y30_RS07180	COG1120	ATPase activity
F3Y30_RS07185	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS07190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS07210	COG3712	iron ion homeostasis
F3Y30_RS07215	COG1595	DNA-templated transcription, initiation
F3Y30_RS07225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3Y30_RS07295	COG1222	aaa ATPase
F3Y30_RS07335	COG2195	Cleaves the N-terminal amino acid of tripeptides
F3Y30_RS07340	COG0490	domain, Protein
F3Y30_RS07340	COG0471	metal ion transport
F3Y30_RS07350	COG1863	multisubunit Na H antiporter MnhE subunit
F3Y30_RS07355	COG2212	antiporter activity
F3Y30_RS07370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3Y30_RS07370	COG2111	Na H antiporter
F3Y30_RS07375	COG1006	Multisubunit Na H antiporter MnhC subunit
F3Y30_RS07380	COG0651	ATP synthesis coupled electron transport
F3Y30_RS07395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3Y30_RS07445	COG2936	dipeptidyl-peptidase activity
F3Y30_RS07455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3Y30_RS07470	COG4166	transmembrane transport
F3Y30_RS07495	COG2719	SpoVR family
F3Y30_RS07500	COG2718	Belongs to the UPF0229 family
F3Y30_RS07505	COG2766	serine protein kinase
F3Y30_RS07525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS07530	COG1120	ATPase activity
F3Y30_RS07560	COG0741	lytic transglycosylase activity
F3Y30_RS07560	COG1196	nuclear chromosome segregation
F3Y30_RS07560	COG0739	heme binding
F3Y30_RS07570	COG0436	Aminotransferase
F3Y30_RS07580	COG2169	Transcriptional regulator
F3Y30_RS07580	COG1917	Cupin 2, conserved barrel domain protein
F3Y30_RS07605	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F3Y30_RS07615	COG0477	Major facilitator Superfamily
F3Y30_RS07635	COG0412	Dienelactone hydrolase
F3Y30_RS07640	COG0583	DNA-binding transcription factor activity
F3Y30_RS07670	COG0306	phosphate transporter
F3Y30_RS07680	COG2186	Transcriptional regulator
F3Y30_RS07690	COG0583	DNA-binding transcription factor activity
F3Y30_RS07695	COG0277	FAD linked oxidase domain protein
F3Y30_RS07700	COG0277	FAD linked oxidase domain protein
F3Y30_RS07705	COG0247	lactate metabolic process
F3Y30_RS07710	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS07715	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS07720	COG2818	Glycosylase
F3Y30_RS07750	COG0124	histidyl-tRNA synthetase
F3Y30_RS07755	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
F3Y30_RS07760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F3Y30_RS07770	COG0625	glutathione transferase activity
F3Y30_RS07780	COG3300	MHYT domain
F3Y30_RS07780	COG5001	Diguanylate cyclase
F3Y30_RS07790	COG0459	protein refolding
F3Y30_RS07795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F3Y30_RS07805	COG2059	Chromate
F3Y30_RS07815	COG0196	riboflavin kinase activity
F3Y30_RS07820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F3Y30_RS07830	COG0456	acetyltransferase
F3Y30_RS07840	COG0590	tRNA wobble adenosine to inosine editing
F3Y30_RS07845	COG1187	pseudouridine synthase activity
F3Y30_RS07850	COG0742	ribosomal rna small subunit methyltransferase
F3Y30_RS07860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3Y30_RS07860	COG0475	glutathione-regulated potassium exporter activity
F3Y30_RS07865	COG0312	modulator of DNA gyrase
F3Y30_RS07870	COG0483	inositol monophosphate 1-phosphatase activity
F3Y30_RS07880	COG1519	Transferase
F3Y30_RS07885	COG0546	phosphoglycolate phosphatase activity
F3Y30_RS07890	COG1663	tetraacyldisaccharide 4'-kinase activity
F3Y30_RS07900	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F3Y30_RS07910	COG3300	MHYT domain
F3Y30_RS07910	COG5001	Diguanylate cyclase
F3Y30_RS07925	COG5598	trimethylamine methyltransferase
F3Y30_RS07940	COG3386	PFAM SMP-30 Gluconolaconase
F3Y30_RS07945	COG0800	Aldolase
F3Y30_RS07950	COG3734	2-keto-3-deoxy-galactonokinase
F3Y30_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS07960	COG1414	Transcriptional regulator
F3Y30_RS07970	COG2771	luxR family
F3Y30_RS07975	COG0489	protein tyrosine kinase activity
F3Y30_RS07980	COG0598	Magnesium transport protein CorA
F3Y30_RS07985	COG3158	transport of potassium into the cell
F3Y30_RS08000	COG0356	it plays a direct role in the translocation of protons across the membrane
F3Y30_RS08005	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F3Y30_RS08010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F3Y30_RS08015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F3Y30_RS08020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F3Y30_RS08035	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3Y30_RS08040	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F3Y30_RS08050	COG0142	geranyltranstransferase activity
F3Y30_RS08065	COG1914	H( )-stimulated, divalent metal cation uptake system
F3Y30_RS08085	COG0752	glycyl-tRNA synthetase alpha subunit
F3Y30_RS08100	COG1704	LemA family
F3Y30_RS08110	COG0751	glycine-tRNA ligase activity
F3Y30_RS08115	COG1683	Conserved Protein
F3Y30_RS08125	COG0151	Belongs to the GarS family
F3Y30_RS08165	COG0009	L-threonylcarbamoyladenylate synthase
F3Y30_RS08180	COG4638	Rieske (2fe-2S)
F3Y30_RS08185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3Y30_RS08205	COG1960	acyl-CoA dehydrogenase activity
F3Y30_RS08210	COG1024	Enoyl-CoA hydratase
F3Y30_RS08225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F3Y30_RS08235	COG0840	transmembrane signaling receptor activity
F3Y30_RS08245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F3Y30_RS08250	COG1741	Belongs to the pirin family
F3Y30_RS08255	COG1722	exodeoxyribonuclease VII activity
F3Y30_RS08260	COG0123	including yeast histone deacetylase and acetoin utilization protein
F3Y30_RS08270	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F3Y30_RS08275	COG1122	ATPase activity
F3Y30_RS08295	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3Y30_RS08295	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3Y30_RS08320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3Y30_RS08325	COG0484	heat shock protein binding
F3Y30_RS08335	COG0259	pyridoxamine-phosphate oxidase activity
F3Y30_RS08345	COG0312	modulator of DNA gyrase
F3Y30_RS08355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3Y30_RS08360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3Y30_RS08365	COG0109	protoheme IX farnesyltransferase activity
F3Y30_RS08375	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
F3Y30_RS08390	COG3346	SURF1 family
F3Y30_RS08400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F3Y30_RS08405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3Y30_RS08410	COG0328	RNA-DNA hybrid ribonuclease activity
F3Y30_RS08425	COG0678	peroxiredoxin activity
F3Y30_RS08425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3Y30_RS08450	COG5001	Diguanylate cyclase
F3Y30_RS08455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3Y30_RS08475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3Y30_RS08495	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F3Y30_RS08505	COG1194	a g-specific adenine glycosylase
F3Y30_RS08520	COG1196	nuclear chromosome segregation
F3Y30_RS08540	COG0574	Belongs to the PEP-utilizing enzyme family
F3Y30_RS08540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3Y30_RS08575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3Y30_RS08595	COG2226	methyltransferase
F3Y30_RS08605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3Y30_RS08615	COG0697	spore germination
F3Y30_RS08630	COG1285	pathogenesis
F3Y30_RS08640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3Y30_RS08650	COG2895	sulfate adenylyltransferase (ATP) activity
F3Y30_RS08660	COG0175	sulfate reduction
F3Y30_RS08670	COG1959	2 iron, 2 sulfur cluster binding
F3Y30_RS08675	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F3Y30_RS08680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F3Y30_RS08685	COG4208	sulfate ABC transporter
F3Y30_RS08690	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3Y30_RS08705	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
F3Y30_RS08710	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS08715	COG3119	arylsulfatase activity
F3Y30_RS08720	COG1309	transcriptional regulator
F3Y30_RS08730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F3Y30_RS08750	COG3321	synthase
F3Y30_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS08750	COG0604	alcohol dehydrogenase
F3Y30_RS08785	COG0625	glutathione transferase activity
F3Y30_RS08795	COG0583	DNA-binding transcription factor activity
F3Y30_RS08800	COG0625	glutathione transferase activity
F3Y30_RS08805	COG0659	secondary active sulfate transmembrane transporter activity
F3Y30_RS08860	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS08865	COG1846	Transcriptional regulator
F3Y30_RS08870	COG1764	response to oxidative stress
F3Y30_RS08885	COG0433	COG0433 Predicted ATPase
F3Y30_RS08900	COG0656	L-ascorbic acid biosynthetic process
F3Y30_RS08905	COG2814	Major facilitator Superfamily
F3Y30_RS08920	COG4106	trans-aconitate 2-methyltransferase activity
F3Y30_RS08935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3Y30_RS08945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3Y30_RS08965	COG3909	cytochrome
F3Y30_RS08970	COG2010	Cytochrome c
F3Y30_RS08985	COG0693	protein deglycase activity
F3Y30_RS09000	COG4993	Dehydrogenase
F3Y30_RS09005	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F3Y30_RS09015	COG1309	transcriptional regulator
F3Y30_RS09045	COG0583	DNA-binding transcription factor activity
F3Y30_RS09065	COG2514	catechol 2,3-dioxygenase activity
F3Y30_RS09095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3Y30_RS09100	COG2111	Na H antiporter
F3Y30_RS09100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3Y30_RS09105	COG2111	Na H antiporter
F3Y30_RS09110	COG1006	Multisubunit Na H antiporter MnhC subunit
F3Y30_RS09115	COG0651	ATP synthesis coupled electron transport
F3Y30_RS09125	COG2212	antiporter activity
F3Y30_RS09130	COG1320	monovalent cation:proton antiporter activity
F3Y30_RS09135	COG4957	zinc ion binding
F3Y30_RS09140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F3Y30_RS09150	COG2166	iron-sulfur cluster assembly
F3Y30_RS09160	COG2205	protein histidine kinase activity
F3Y30_RS09200	COG2983	Belongs to the UPF0260 family
F3Y30_RS09230	COG4695	Portal protein
F3Y30_RS09570	COG4235	cytochrome complex assembly
F3Y30_RS09575	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F3Y30_RS09580	COG1138	Cytochrome C-type biogenesis protein
F3Y30_RS09590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3Y30_RS09595	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS09610	COG2202	Pas domain
F3Y30_RS09610	COG2205	protein histidine kinase activity
F3Y30_RS09615	COG0308	aminopeptidase N
F3Y30_RS09625	COG0840	transmembrane signaling receptor activity
F3Y30_RS09655	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS09690	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS09700	COG4176	ABC-type proline glycine betaine transport system permease component
F3Y30_RS09710	COG2814	Major facilitator Superfamily
F3Y30_RS09720	COG0174	glutamine synthetase
F3Y30_RS09730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3Y30_RS09735	COG0463	Glycosyl transferase, family 2
F3Y30_RS09745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3Y30_RS09750	COG1742	UPF0060 membrane protein
F3Y30_RS09760	COG0625	glutathione transferase activity
F3Y30_RS09785	COG1960	acyl-CoA dehydrogenase activity
F3Y30_RS09820	COG0596	Alpha beta hydrolase
F3Y30_RS09830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3Y30_RS09835	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F3Y30_RS09850	COG1758	RNA polymerase activity
F3Y30_RS09870	COG0736	holo-[acyl-carrier-protein] synthase activity
F3Y30_RS09875	COG0681	Belongs to the peptidase S26 family
F3Y30_RS09880	COG0571	ribonuclease III activity
F3Y30_RS09885	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F3Y30_RS09890	COG5001	Diguanylate cyclase
F3Y30_RS09900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3Y30_RS09905	COG2183	response to ionizing radiation
F3Y30_RS09915	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
F3Y30_RS09915	COG0392	lysyltransferase activity
F3Y30_RS09935	COG1381	Involved in DNA repair and RecF pathway recombination
F3Y30_RS09950	COG2755	lipolytic protein G-D-S-L family
F3Y30_RS09950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3Y30_RS09955	COG0633	Ferredoxin
F3Y30_RS09955	COG3217	Mosc domain protein beta barrel domain protein
F3Y30_RS09965	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F3Y30_RS09970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F3Y30_RS09995	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F3Y30_RS10020	COG0494	nUDIX hydrolase
F3Y30_RS10040	COG0215	cysteine-tRNA ligase activity
F3Y30_RS10065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3Y30_RS10085	COG5265	(ABC) transporter
F3Y30_RS10090	COG0688	phosphatidylethanolamine metabolic process
F3Y30_RS10095	COG1183	phosphatidylcholine synthase activity
F3Y30_RS10105	COG4221	oxidoreductase activity
F3Y30_RS10110	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3Y30_RS10125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3Y30_RS10150	COG0305	Participates in initiation and elongation during chromosome replication
F3Y30_RS10155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3Y30_RS10160	COG0359	binds to the 23S rRNA
F3Y30_RS10170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F3Y30_RS10175	COG0360	Binds together with S18 to 16S ribosomal RNA
F3Y30_RS10190	COG0667	Aldo Keto reductase
F3Y30_RS10195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F3Y30_RS10205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3Y30_RS10215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3Y30_RS10225	COG0194	GDP metabolic process
F3Y30_RS10230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F3Y30_RS10235	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F3Y30_RS10245	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F3Y30_RS10260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F3Y30_RS10280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3Y30_RS10285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F3Y30_RS10300	COG0488	(ABC) transporter
F3Y30_RS10315	COG0840	transmembrane signaling receptor activity
F3Y30_RS10330	COG0105	UTP biosynthetic process
F3Y30_RS10350	COG0314	molybdopterin synthase activity
F3Y30_RS10360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3Y30_RS10370	COG0322	excinuclease ABC activity
F3Y30_RS10400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F3Y30_RS10405	COG0243	molybdopterin cofactor binding
F3Y30_RS10420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F3Y30_RS10425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F3Y30_RS10430	COG0628	permease
F3Y30_RS10440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F3Y30_RS10445	COG0248	Ppx GppA phosphatase
F3Y30_RS10470	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F3Y30_RS10475	COG2132	Multicopper oxidase
F3Y30_RS10510	COG0697	spore germination
F3Y30_RS10535	COG3119	arylsulfatase activity
F3Y30_RS10540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F3Y30_RS10555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3Y30_RS10565	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
F3Y30_RS10575	COG0113	porphobilinogen synthase activity
F3Y30_RS10590	COG2989	Protein conserved in bacteria
F3Y30_RS10595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F3Y30_RS10600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F3Y30_RS10605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3Y30_RS10605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3Y30_RS10625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F3Y30_RS10630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3Y30_RS10635	COG2814	Major facilitator Superfamily
F3Y30_RS10640	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F3Y30_RS10660	COG0416	fatty acid biosynthetic process
F3Y30_RS10665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3Y30_RS10670	COG0776	regulation of translation
F3Y30_RS10700	COG0443	Heat shock 70 kDa protein
F3Y30_RS10710	COG1686	Belongs to the peptidase S11 family
F3Y30_RS10715	COG0456	acetyltransferase
F3Y30_RS10720	COG3585	molybdate ion transport
F3Y30_RS10725	COG3781	membrane
F3Y30_RS10730	COG3119	arylsulfatase activity
F3Y30_RS10740	COG0438	transferase activity, transferring glycosyl groups
F3Y30_RS10785	COG1612	heme a metabolic process
F3Y30_RS10790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F3Y30_RS10795	COG0010	Belongs to the arginase family
F3Y30_RS10805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F3Y30_RS10810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F3Y30_RS10820	COG1024	Enoyl-CoA hydratase
F3Y30_RS10830	COG1832	CoA-binding protein
F3Y30_RS10835	COG1832	CoA-binding protein
F3Y30_RS10860	COG0405	Gamma-glutamyltransferase
F3Y30_RS10865	COG0740	serine-type endopeptidase activity
F3Y30_RS10870	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F3Y30_RS10875	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3Y30_RS10880	COG0776	regulation of translation
F3Y30_RS10910	COG0420	3'-5' exonuclease activity
F3Y30_RS10940	COG0583	DNA-binding transcription factor activity
F3Y30_RS10950	COG1312	Catalyzes the dehydration of D-mannonate
F3Y30_RS10955	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS10960	COG0667	Aldo Keto reductase
F3Y30_RS10995	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3Y30_RS11000	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3Y30_RS11005	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3Y30_RS11010	COG0649	NAD binding
F3Y30_RS11020	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F3Y30_RS11025	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F3Y30_RS11030	COG3743	rRNA binding
F3Y30_RS11030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F3Y30_RS11040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
F3Y30_RS11045	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3Y30_RS11055	COG0713	ATP synthesis coupled electron transport
F3Y30_RS11070	COG1007	ATP synthesis coupled electron transport
F3Y30_RS11085	COG0346	lactoylglutathione lyase activity
F3Y30_RS11095	COG0442	prolyl-tRNA aminoacylation
F3Y30_RS11105	COG1136	(ABC) transporter
F3Y30_RS11125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3Y30_RS11140	COG0784	Response regulator, receiver
F3Y30_RS11150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F3Y30_RS11155	COG0477	Major facilitator Superfamily
F3Y30_RS11170	COG0557	exoribonuclease II activity
F3Y30_RS11175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3Y30_RS11175	COG1754	DNA topoisomerase type I activity
F3Y30_RS11185	COG0758	DNA mediated transformation
F3Y30_RS11190	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
F3Y30_RS11195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F3Y30_RS11200	COG0540	Belongs to the ATCase OTCase family
F3Y30_RS11205	COG1960	acyl-CoA dehydrogenase activity
F3Y30_RS11220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F3Y30_RS11225	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F3Y30_RS11230	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3Y30_RS11235	COG0456	acetyltransferase
F3Y30_RS11240	COG0154	amidase activity
F3Y30_RS11250	COG3811	Belongs to the UPF0386 family
F3Y30_RS11260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3Y30_RS11285	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F3Y30_RS11295	COG0511	ligase activity, forming carbon-carbon bonds
F3Y30_RS11300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F3Y30_RS11310	COG0436	Aminotransferase
F3Y30_RS11315	COG1530	ribonuclease E activity
F3Y30_RS11320	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3Y30_RS11325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3Y30_RS11370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3Y30_RS11400	COG1238	metal cluster binding
F3Y30_RS11405	COG0583	DNA-binding transcription factor activity
F3Y30_RS11410	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS11420	COG2133	pyrroloquinoline quinone binding
F3Y30_RS11425	COG0300	oxidoreductase activity
F3Y30_RS11430	COG1064	alcohol dehydrogenase
F3Y30_RS11440	COG4221	oxidoreductase activity
F3Y30_RS11450	COG1733	regulation of RNA biosynthetic process
F3Y30_RS11455	COG0604	alcohol dehydrogenase
F3Y30_RS11460	COG0583	DNA-binding transcription factor activity
F3Y30_RS11470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F3Y30_RS11475	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F3Y30_RS11480	COG0583	DNA-binding transcription factor activity
F3Y30_RS11485	COG1073	alpha beta
F3Y30_RS11560	COG2132	Multicopper oxidase
F3Y30_RS11630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3Y30_RS11640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3Y30_RS11965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F3Y30_RS11985	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3Y30_RS11995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F3Y30_RS12000	COG0081	regulation of translation
F3Y30_RS12005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F3Y30_RS12010	COG0222	ribosome binding
F3Y30_RS12015	COG0085	RNA polymerase activity
F3Y30_RS12020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F3Y30_RS12030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F3Y30_RS12035	COG0049	tRNA binding
F3Y30_RS12045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F3Y30_RS12055	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F3Y30_RS12060	COG0088	Forms part of the polypeptide exit tunnel
F3Y30_RS12065	COG0089	rRNA binding
F3Y30_RS12070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F3Y30_RS12075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F3Y30_RS12080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F3Y30_RS12085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F3Y30_RS12090	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F3Y30_RS12095	COG0255	Belongs to the universal ribosomal protein uL29 family
F3Y30_RS12100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F3Y30_RS12110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F3Y30_RS12115	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F3Y30_RS12120	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F3Y30_RS12125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F3Y30_RS12130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F3Y30_RS12135	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F3Y30_RS12140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F3Y30_RS12145	COG1841	ribosomal large subunit assembly
F3Y30_RS12150	COG0200	Binds to the 23S rRNA
F3Y30_RS12155	COG0201	protein transport
F3Y30_RS12165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F3Y30_RS12170	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F3Y30_RS12175	COG0202	RNA polymerase activity
F3Y30_RS12180	COG0203	ribosomal protein L17
F3Y30_RS12190	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
F3Y30_RS12195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3Y30_RS12205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F3Y30_RS12225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3Y30_RS12245	COG0484	heat shock protein binding
F3Y30_RS12255	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
F3Y30_RS12305	COG4191	Histidine kinase
F3Y30_RS12310	COG4566	intracellular signal transduction
F3Y30_RS12320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3Y30_RS12330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3Y30_RS12355	COG0243	molybdopterin cofactor binding
F3Y30_RS12365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3Y30_RS12470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3Y30_RS12475	COG2368	4-hydroxyphenylacetate
F3Y30_RS12485	COG0583	DNA-binding transcription factor activity
F3Y30_RS12505	COG0583	DNA-binding transcription factor activity
F3Y30_RS12540	COG1942	4-Oxalocrotonate Tautomerase
F3Y30_RS12550	COG1522	sequence-specific DNA binding
F3Y30_RS12570	COG0384	phenazine biosynthesis protein PhzF
F3Y30_RS12600	COG2814	Major facilitator Superfamily
F3Y30_RS12605	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3Y30_RS12615	COG4191	Histidine kinase
F3Y30_RS12620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3Y30_RS12650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3Y30_RS12655	COG1131	(ABC) transporter
F3Y30_RS12660	COG0842	Transport permease protein
F3Y30_RS12665	COG0842	Transport permease protein
F3Y30_RS12670	COG4191	Histidine kinase
F3Y30_RS12685	COG4566	intracellular signal transduction
F3Y30_RS12690	COG4566	intracellular signal transduction
F3Y30_RS12710	COG3938	Belongs to the proline racemase family
F3Y30_RS12715	COG1802	Transcriptional regulator
F3Y30_RS12720	COG3938	Belongs to the proline racemase family
F3Y30_RS12725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3Y30_RS12730	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F3Y30_RS12740	COG1546	Belongs to the CinA family
F3Y30_RS12740	COG1058	Belongs to the CinA family
F3Y30_RS12745	COG0655	NAD(P)H dehydrogenase (quinone) activity
F3Y30_RS12765	COG3646	Phage regulatory protein
F3Y30_RS12775	COG3646	Phage regulatory protein
F3Y30_RS12835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F3Y30_RS12840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3Y30_RS12850	COG5001	Diguanylate cyclase
F3Y30_RS12850	COG3300	MHYT domain
F3Y30_RS12855	COG3706	GGDEF domain
F3Y30_RS12860	COG1522	sequence-specific DNA binding
F3Y30_RS12865	COG0686	Belongs to the AlaDH PNT family
F3Y30_RS12885	COG2897	thiosulfate sulfurtransferase activity
F3Y30_RS12890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F3Y30_RS12905	COG4221	oxidoreductase activity
F3Y30_RS12960	COG0667	Aldo Keto reductase
F3Y30_RS12975	COG1309	transcriptional regulator
F3Y30_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS12990	COG0583	DNA-binding transcription factor activity
F3Y30_RS13000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F3Y30_RS13005	COG3119	arylsulfatase activity
F3Y30_RS13020	COG0640	Transcriptional regulator
F3Y30_RS13085	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3Y30_RS13100	COG0525	valine-tRNA ligase activity
F3Y30_RS13110	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F3Y30_RS13120	COG2233	PERMEase
F3Y30_RS13125	COG0316	Belongs to the HesB IscA family
F3Y30_RS13130	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F3Y30_RS13135	COG0018	arginyl-trna synthetase
F3Y30_RS13145	COG1472	Belongs to the glycosyl hydrolase 3 family
F3Y30_RS13150	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F3Y30_RS13155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F3Y30_RS13165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3Y30_RS13170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3Y30_RS13175	COG0805	protein transport
F3Y30_RS13180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F3Y30_RS13185	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F3Y30_RS13190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3Y30_RS13210	COG1862	Preprotein translocase
F3Y30_RS13235	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
F3Y30_RS13265	COG0544	peptidyl-prolyl cis-trans isomerase activity
F3Y30_RS13275	COG0598	Magnesium transport protein CorA
F3Y30_RS13280	COG2003	Belongs to the UPF0758 family
F3Y30_RS13285	COG0024	Methionine aminopeptidase
F3Y30_RS13290	COG1489	DNA binding
F3Y30_RS13295	COG3243	poly(R)-hydroxyalkanoic acid synthase
F3Y30_RS13305	COG0436	Aminotransferase
F3Y30_RS13315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F3Y30_RS13375	COG1278	Cold shock
F3Y30_RS13395	COG1760	l-serine dehydratase
F3Y30_RS13410	COG1686	Belongs to the peptidase S11 family
F3Y30_RS13445	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3Y30_RS13450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F3Y30_RS13455	COG0302	gtp cyclohydrolase
F3Y30_RS13465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F3Y30_RS13475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F3Y30_RS13480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F3Y30_RS13515	COG0187	DNA topoisomerase II activity
F3Y30_RS13525	COG0149	triose-phosphate isomerase activity
F3Y30_RS13530	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3Y30_RS13535	COG0504	CTP synthase activity
F3Y30_RS13545	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F3Y30_RS13550	COG0148	phosphopyruvate hydratase activity
F3Y30_RS13560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3Y30_RS13565	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3Y30_RS13565	COG0022	dehydrogenase e1 component
F3Y30_RS13570	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3Y30_RS13580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3Y30_RS13585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F3Y30_RS13595	COG2867	negative regulation of translational initiation
F3Y30_RS13600	COG1546	Belongs to the CinA family
F3Y30_RS13605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F3Y30_RS13605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F3Y30_RS13615	COG3852	Histidine kinase
F3Y30_RS13620	COG2204	response regulator
F3Y30_RS13625	COG5000	phosphorelay sensor kinase activity
F3Y30_RS13630	COG2204	response regulator
F3Y30_RS13635	COG0569	domain protein
F3Y30_RS13640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3Y30_RS13645	COG1923	regulation of RNA biosynthetic process
F3Y30_RS13650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3Y30_RS13655	COG3956	TIGRFAM MazG family protein
F3Y30_RS13665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F3Y30_RS13665	COG1648	precorrin-2 dehydrogenase activity
F3Y30_RS13675	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3Y30_RS13705	COG2010	Cytochrome c
F3Y30_RS13735	COG0628	permease
F3Y30_RS13745	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
F3Y30_RS13750	COG0786	glutamate:sodium symporter activity
F3Y30_RS13765	COG3842	ATPase activity
F3Y30_RS13770	COG1177	transmembrane transport
F3Y30_RS13795	COG0785	Cytochrome C biogenesis protein
F3Y30_RS13800	COG0679	Auxin Efflux Carrier
F3Y30_RS13805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3Y30_RS13810	COG1183	phosphatidylcholine synthase activity
F3Y30_RS13820	COG3845	ABC transporter
F3Y30_RS13825	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS13830	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS13840	COG1879	ABC-type sugar transport system periplasmic component
F3Y30_RS13845	COG1129	ABC transporter
F3Y30_RS13850	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS13855	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS13860	COG2186	Transcriptional regulator
F3Y30_RS13880	COG1917	Cupin 2, conserved barrel domain protein
F3Y30_RS13880	COG1396	sequence-specific DNA binding
F3Y30_RS13900	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F3Y30_RS13910	COG1181	Belongs to the D-alanine--D-alanine ligase family
F3Y30_RS13930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3Y30_RS13935	COG1686	Belongs to the peptidase S11 family
F3Y30_RS13940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F3Y30_RS13950	COG0730	response to heat
F3Y30_RS13955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3Y30_RS13960	COG0084	hydrolase, TatD family'
F3Y30_RS13965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F3Y30_RS13965	COG0321	lipoyl(octanoyl) transferase activity
F3Y30_RS13970	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F3Y30_RS14000	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F3Y30_RS14010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3Y30_RS14015	COG2095	MarC family integral membrane protein
F3Y30_RS14020	COG0629	single-stranded DNA binding
F3Y30_RS14025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3Y30_RS14035	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F3Y30_RS14035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F3Y30_RS14040	COG0347	Belongs to the P(II) protein family
F3Y30_RS14045	COG0174	glutamine synthetase
F3Y30_RS14060	COG4166	transmembrane transport
F3Y30_RS14070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F3Y30_RS14095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3Y30_RS14100	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F3Y30_RS14105	COG1283	sodium-dependent phosphate transmembrane transporter activity
F3Y30_RS14120	COG0134	indole-3-glycerol-phosphate synthase activity
F3Y30_RS14125	COG0315	cyclic pyranopterin monophosphate synthase activity
F3Y30_RS14135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3Y30_RS14145	COG0372	Belongs to the citrate synthase family
F3Y30_RS14150	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3Y30_RS14160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3Y30_RS14165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3Y30_RS14180	COG0750	zinc metalloprotease
F3Y30_RS14190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F3Y30_RS14195	COG0233	cytoplasmic translational termination
F3Y30_RS14205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F3Y30_RS14210	COG0052	Belongs to the universal ribosomal protein uS2 family
F3Y30_RS14235	COG0537	adenosine 5'-monophosphoramidase activity
F3Y30_RS14255	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F3Y30_RS14275	COG0596	Alpha beta hydrolase
F3Y30_RS14290	COG0626	cystathionine gamma-synthase activity
F3Y30_RS14295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3Y30_RS14300	COG4597	amino acid ABC transporter
F3Y30_RS14310	COG1126	abc transporter atp-binding protein
F3Y30_RS14380	COG0242	peptide deformylase activity
F3Y30_RS14450	COG0321	lipoyl(octanoyl) transferase activity
F3Y30_RS14470	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F3Y30_RS14480	COG1671	Belongs to the UPF0178 family
F3Y30_RS14490	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F3Y30_RS14495	COG2259	Doxx family
F3Y30_RS14510	COG0546	phosphoglycolate phosphatase activity
F3Y30_RS14530	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3Y30_RS14535	COG0509	glycine decarboxylation via glycine cleavage system
F3Y30_RS14540	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F3Y30_RS14540	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F3Y30_RS14550	COG4251	negative regulation of phosphorylation
F3Y30_RS14565	COG2151	metal-sulfur cluster biosynthetic enzyme
F3Y30_RS14570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3Y30_RS14575	COG0719	Fe-S assembly protein
F3Y30_RS14580	COG0396	ATPase activity
F3Y30_RS14585	COG0719	Fe-S assembly protein
F3Y30_RS14595	COG2945	thiolester hydrolase activity
F3Y30_RS14605	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F3Y30_RS14610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F3Y30_RS14620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F3Y30_RS14625	COG2833	Protein of unknown function (DUF455)
F3Y30_RS14630	COG0739	heme binding
F3Y30_RS14635	COG0513	Belongs to the DEAD box helicase family
F3Y30_RS14645	COG4206	TonB-dependent receptor
F3Y30_RS14645	COG1629	transport
F3Y30_RS14655	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F3Y30_RS14660	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F3Y30_RS14660	COG3608	succinylglutamate desuccinylase aspartoacylase
F3Y30_RS14675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3Y30_RS14680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3Y30_RS14690	COG3191	aminopeptidase activity
F3Y30_RS14710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3Y30_RS14735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F3Y30_RS14740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3Y30_RS14745	COG0047	phosphoribosylformylglycinamidine synthase activity
F3Y30_RS14760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3Y30_RS14780	COG2814	Major facilitator Superfamily
F3Y30_RS14785	COG0483	inositol monophosphate 1-phosphatase activity
F3Y30_RS14790	COG0037	tRNA processing
F3Y30_RS14795	COG2066	Belongs to the glutaminase family
F3Y30_RS14800	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F3Y30_RS14805	COG0861	Integral membrane protein TerC family
F3Y30_RS14815	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F3Y30_RS14830	COG0538	isocitrate dehydrogenase activity
F3Y30_RS14835	COG0438	transferase activity, transferring glycosyl groups
F3Y30_RS14840	COG0561	phosphatase activity
F3Y30_RS14850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F3Y30_RS14855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F3Y30_RS14865	COG2313	pseudouridylate synthase activity
F3Y30_RS14895	COG3768	UPF0283 membrane protein
F3Y30_RS14905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F3Y30_RS14925	COG0492	ferredoxin-NADP+ reductase activity
F3Y30_RS14930	COG0633	Ferredoxin
F3Y30_RS14945	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F3Y30_RS14945	COG3218	ABC-type transport auxiliary lipoprotein component
F3Y30_RS14955	COG1127	ABC transporter
F3Y30_RS14960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F3Y30_RS14965	COG4948	Mandelate Racemase Muconate Lactonizing
F3Y30_RS14970	COG2814	Major facilitator Superfamily
F3Y30_RS14980	COG0281	malic enzyme
F3Y30_RS14980	COG0280	phosphate acetyltransferase
F3Y30_RS14995	COG0778	Nitroreductase
F3Y30_RS15005	COG0823	Involved in the tonB-independent uptake of proteins
F3Y30_RS15015	COG1368	sulfuric ester hydrolase activity
F3Y30_RS15025	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
F3Y30_RS15040	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F3Y30_RS15045	COG0546	phosphoglycolate phosphatase activity
F3Y30_RS15055	COG0114	fumarate hydratase activity
F3Y30_RS15060	COG3706	GGDEF domain
F3Y30_RS15065	COG1388	LysM domain
F3Y30_RS15065	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS15075	COG0475	glutathione-regulated potassium exporter activity
F3Y30_RS15075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3Y30_RS15085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F3Y30_RS15090	COG0840	transmembrane signaling receptor activity
F3Y30_RS15105	COG1763	Mo-molybdopterin cofactor biosynthetic process
F3Y30_RS15130	COG5425	PFAM Usg family protein
F3Y30_RS15150	COG1116	anion transmembrane transporter activity
F3Y30_RS15155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3Y30_RS15160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3Y30_RS15165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3Y30_RS15170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3Y30_RS15175	COG2084	Dehydrogenase
F3Y30_RS15185	COG1522	sequence-specific DNA binding
F3Y30_RS15190	COG1573	uracil-dna glycosylase
F3Y30_RS15195	COG2205	protein histidine kinase activity
F3Y30_RS15195	COG2202	Pas domain
F3Y30_RS15200	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F3Y30_RS15205	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F3Y30_RS15210	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F3Y30_RS15230	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3Y30_RS15250	COG0842	Transport permease protein
F3Y30_RS15255	COG1131	(ABC) transporter
F3Y30_RS15260	COG0730	response to heat
F3Y30_RS15310	COG0556	nucleotide-excision repair
F3Y30_RS15315	COG1192	Involved in chromosome partitioning
F3Y30_RS15355	COG0484	heat shock protein binding
F3Y30_RS15360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3Y30_RS15375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3Y30_RS15380	COG1121	(ABC) transporter
F3Y30_RS15395	COG3507	Belongs to the glycosyl hydrolase 43 family
F3Y30_RS15400	COG0667	Aldo Keto reductase
F3Y30_RS15420	COG3250	beta-galactosidase activity
F3Y30_RS15425	COG3842	ATPase activity
F3Y30_RS15430	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS15435	COG1175	transmembrane transport
F3Y30_RS15450	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F3Y30_RS15520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3Y30_RS15525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3Y30_RS15535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3Y30_RS15540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3Y30_RS15580	COG2610	gluconate transmembrane transporter activity
F3Y30_RS15640	COG0517	IMP dehydrogenase activity
F3Y30_RS15640	COG4175	Glycine betaine
F3Y30_RS15645	COG1410	methionine synthase
F3Y30_RS15645	COG0646	methionine synthase
F3Y30_RS15660	COG5598	trimethylamine methyltransferase
F3Y30_RS15665	COG5012	cobalamin binding
F3Y30_RS15680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F3Y30_RS15700	COG0646	methionine synthase
F3Y30_RS15700	COG1410	methionine synthase
F3Y30_RS15715	COG0583	DNA-binding transcription factor activity
F3Y30_RS15745	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS15755	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F3Y30_RS15755	COG3264	Mechanosensitive ion channel
F3Y30_RS15775	COG2094	Belongs to the DNA glycosylase MPG family
F3Y30_RS15785	COG3707	response regulator
F3Y30_RS15790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3Y30_RS15795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3Y30_RS15800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3Y30_RS15805	COG1116	anion transmembrane transporter activity
F3Y30_RS15810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3Y30_RS15820	COG0243	molybdopterin cofactor binding
F3Y30_RS15825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F3Y30_RS15825	COG1648	precorrin-2 dehydrogenase activity
F3Y30_RS15850	COG0584	glycerophosphoryl diester phosphodiesterase
F3Y30_RS15855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3Y30_RS15860	COG0601	transmembrane transport
F3Y30_RS15865	COG4608	Belongs to the ABC transporter superfamily
F3Y30_RS15875	COG0747	negative chemotaxis
F3Y30_RS15885	COG1215	transferase activity, transferring glycosyl groups
F3Y30_RS15910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3Y30_RS15910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F3Y30_RS15920	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS15925	COG4221	oxidoreductase activity
F3Y30_RS15945	COG1902	pentaerythritol trinitrate reductase activity
F3Y30_RS15975	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS15990	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS16015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F3Y30_RS16045	COG3845	ABC transporter
F3Y30_RS16055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F3Y30_RS16060	COG0667	Aldo Keto reductase
F3Y30_RS16065	COG1522	sequence-specific DNA binding
F3Y30_RS16070	COG4187	Peptidase family M20/M25/M40
F3Y30_RS16075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3Y30_RS16080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F3Y30_RS16095	COG1278	Cold shock
F3Y30_RS16100	COG1522	sequence-specific DNA binding
F3Y30_RS16105	COG1794	racemase activity, acting on amino acids and derivatives
F3Y30_RS16110	COG1846	Transcriptional regulator
F3Y30_RS16110	COG0456	acetyltransferase
F3Y30_RS16115	COG1733	regulation of RNA biosynthetic process
F3Y30_RS16125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F3Y30_RS16140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3Y30_RS16145	COG3180	Ammonia monooxygenase
F3Y30_RS16185	COG0656	L-ascorbic acid biosynthetic process
F3Y30_RS16205	COG2010	Cytochrome c
F3Y30_RS16230	COG0440	acetolactate synthase activity
F3Y30_RS16235	COG0028	Belongs to the TPP enzyme family
F3Y30_RS16245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F3Y30_RS16250	COG0560	Phosphoserine phosphatase
F3Y30_RS16265	COG0330	HflC and HflK could
F3Y30_RS16270	COG0330	HflC and HflK could
F3Y30_RS16280	COG0625	glutathione transferase activity
F3Y30_RS16285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F3Y30_RS16320	COG0277	FAD linked oxidase domain protein
F3Y30_RS16330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3Y30_RS16340	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
F3Y30_RS16350	COG0210	DNA helicase
F3Y30_RS16375	COG3119	arylsulfatase activity
F3Y30_RS16405	COG0384	phenazine biosynthesis protein PhzF
F3Y30_RS16440	COG4638	Rieske (2fe-2S)
F3Y30_RS16445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3Y30_RS16455	COG1177	transmembrane transport
F3Y30_RS16460	COG3842	ATPase activity
F3Y30_RS16475	COG1309	transcriptional regulator
F3Y30_RS16495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3Y30_RS16510	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS16515	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS16525	COG3842	ATPase activity
F3Y30_RS16540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3Y30_RS16545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3Y30_RS16555	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS16560	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS16565	COG1175	transmembrane transport
F3Y30_RS16575	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F3Y30_RS16580	COG2971	BadF BadG BcrA BcrD
F3Y30_RS16585	COG2188	Transcriptional regulator
F3Y30_RS16590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3Y30_RS16595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3Y30_RS16605	COG3142	Participates in the control of copper homeostasis
F3Y30_RS16615	COG1335	isochorismatase
F3Y30_RS16620	COG0835	chemotaxis
F3Y30_RS16630	COG1999	signal sequence binding
F3Y30_RS16640	COG2264	protein methyltransferase activity
F3Y30_RS16645	COG0006	proline dipeptidase activity
F3Y30_RS16660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F3Y30_RS16665	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F3Y30_RS16670	COG0513	Belongs to the DEAD box helicase family
F3Y30_RS16680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F3Y30_RS16685	COG0497	DNA recombination
F3Y30_RS16690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3Y30_RS16700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3Y30_RS16705	COG0849	cell division
F3Y30_RS16715	COG1181	Belongs to the D-alanine--D-alanine ligase family
F3Y30_RS16720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F3Y30_RS16725	COG0477	Major facilitator Superfamily
F3Y30_RS16735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F3Y30_RS16745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F3Y30_RS16755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F3Y30_RS16760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F3Y30_RS16770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F3Y30_RS16785	COG0275	rRNA processing
F3Y30_RS16790	COG2001	Belongs to the MraZ family
F3Y30_RS16805	COG3023	N-Acetylmuramoyl-L-alanine amidase
F3Y30_RS16810	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F3Y30_RS16825	COG1280	lysine exporter protein (LysE YggA)
F3Y30_RS16840	COG5001	Diguanylate cyclase
F3Y30_RS16840	COG3300	MHYT domain
F3Y30_RS16870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F3Y30_RS16890	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS16910	COG0028	Belongs to the TPP enzyme family
F3Y30_RS16925	COG2267	carboxylic ester hydrolase activity
F3Y30_RS16945	COG0840	transmembrane signaling receptor activity
F3Y30_RS16965	COG0174	glutamine synthetase
F3Y30_RS16980	COG1737	Transcriptional regulator
F3Y30_RS16980	COG0837	glucose binding
F3Y30_RS17000	COG3842	ATPase activity
F3Y30_RS17005	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F3Y30_RS17010	COG0698	ribose 5-phosphate isomerase
F3Y30_RS17015	COG0149	triose-phosphate isomerase activity
F3Y30_RS17020	COG1349	DNA-binding transcription factor activity
F3Y30_RS17025	COG2197	response regulator
F3Y30_RS17030	COG3842	ATPase activity
F3Y30_RS17045	COG1177	transmembrane transport
F3Y30_RS17050	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS17060	COG3246	L-lysine catabolic process to acetate
F3Y30_RS17070	COG1960	acyl-CoA dehydrogenase activity
F3Y30_RS17085	COG0747	negative chemotaxis
F3Y30_RS17095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3Y30_RS17135	COG0657	acetylesterase activity
F3Y30_RS17145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3Y30_RS17150	COG0583	DNA-binding transcription factor activity
F3Y30_RS17170	COG1522	sequence-specific DNA binding
F3Y30_RS17175	COG2202	Pas domain
F3Y30_RS17175	COG3920	Histidine kinase
F3Y30_RS17180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3Y30_RS17185	COG3842	ATPase activity
F3Y30_RS17190	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS17195	COG1177	transmembrane transport
F3Y30_RS17220	COG1129	ABC transporter
F3Y30_RS17225	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS17235	COG4638	Rieske (2fe-2S)
F3Y30_RS17255	COG0583	DNA-binding transcription factor activity
F3Y30_RS17265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3Y30_RS17270	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
F3Y30_RS17305	COG4585	Histidine kinase
F3Y30_RS17310	COG2197	response regulator
F3Y30_RS17325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3Y30_RS17345	COG0463	Glycosyl transferase, family 2
F3Y30_RS17355	COG0235	Class ii aldolase
F3Y30_RS17370	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS17375	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS17380	COG1129	ABC transporter
F3Y30_RS17395	COG1802	Transcriptional regulator
F3Y30_RS17410	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS17425	COG1335	isochorismatase
F3Y30_RS17445	COG2186	Transcriptional regulator
F3Y30_RS17450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3Y30_RS17455	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS17460	COG3842	ATPase activity
F3Y30_RS17470	COG1175	transmembrane transport
F3Y30_RS17475	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS17485	COG0730	response to heat
F3Y30_RS17495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3Y30_RS17505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3Y30_RS17525	COG1120	ATPase activity
F3Y30_RS17530	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS17535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS17560	COG1595	DNA-templated transcription, initiation
F3Y30_RS17595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F3Y30_RS17595	COG3608	succinylglutamate desuccinylase aspartoacylase
F3Y30_RS17600	COG3493	citrate carrier protein
F3Y30_RS17615	COG3961	Belongs to the TPP enzyme family
F3Y30_RS17620	COG0387	Pfam Sodium calcium exchanger
F3Y30_RS17625	COG0488	(ABC) transporter
F3Y30_RS17655	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS17665	COG3842	ATPase activity
F3Y30_RS17670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3Y30_RS17685	COG0251	oxidation-reduction process
F3Y30_RS17690	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS17695	COG0583	DNA-binding transcription factor activity
F3Y30_RS17705	COG3842	ATPase activity
F3Y30_RS17715	COG1175	transmembrane transport
F3Y30_RS17725	COG0583	DNA-binding transcription factor activity
F3Y30_RS17735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F3Y30_RS17745	COG0747	negative chemotaxis
F3Y30_RS17750	COG0601	transmembrane transport
F3Y30_RS17755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3Y30_RS17765	COG4608	Belongs to the ABC transporter superfamily
F3Y30_RS17800	COG3180	Ammonia monooxygenase
F3Y30_RS17815	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS17820	COG3622	Belongs to the hyi family
F3Y30_RS17825	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3Y30_RS17845	COG0473	3-isopropylmalate dehydrogenase activity
F3Y30_RS17850	COG1802	Transcriptional regulator
F3Y30_RS17855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3Y30_RS17860	COG0235	Class ii aldolase
F3Y30_RS17865	COG3395	kinase activity
F3Y30_RS17875	COG3842	ATPase activity
F3Y30_RS17890	COG0473	3-isopropylmalate dehydrogenase activity
F3Y30_RS17895	COG1802	Transcriptional regulator
F3Y30_RS17900	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3Y30_RS17920	COG0432	Pfam Uncharacterised protein family UPF0047
F3Y30_RS17925	COG5507	3-demethylubiquinone-9 3-methyltransferase
F3Y30_RS17955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3Y30_RS17975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3Y30_RS18000	COG1522	sequence-specific DNA binding
F3Y30_RS18020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3Y30_RS18025	COG1063	alcohol dehydrogenase
F3Y30_RS18040	COG0514	ATP-dependent DNA helicase (RecQ)
F3Y30_RS18045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3Y30_RS18070	COG0358	DNA primase activity
F3Y30_RS18085	COG0505	Belongs to the CarA family
F3Y30_RS18095	COG0534	Mate efflux family protein
F3Y30_RS18105	COG0583	DNA-binding transcription factor activity
F3Y30_RS18115	COG2321	neutral zinc metallopeptidase
F3Y30_RS18120	COG1063	alcohol dehydrogenase
F3Y30_RS18130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F3Y30_RS18140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3Y30_RS18170	COG0492	ferredoxin-NADP+ reductase activity
F3Y30_RS18175	COG0583	DNA-binding transcription factor activity
F3Y30_RS18185	COG1902	pentaerythritol trinitrate reductase activity
F3Y30_RS18195	COG0387	Pfam Sodium calcium exchanger
F3Y30_RS18205	COG0436	Aminotransferase
F3Y30_RS18220	COG2133	pyrroloquinoline quinone binding
F3Y30_RS18230	COG1278	Cold shock
F3Y30_RS18240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3Y30_RS18250	COG1522	sequence-specific DNA binding
F3Y30_RS18265	COG1846	Transcriptional regulator
F3Y30_RS18270	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS18275	COG2205	protein histidine kinase activity
F3Y30_RS18280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3Y30_RS18300	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F3Y30_RS18310	COG1496	oxidoreductase activity
F3Y30_RS18325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F3Y30_RS18350	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS18360	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS18375	COG3135	benzoate transporter
F3Y30_RS18385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F3Y30_RS18390	COG5001	Diguanylate cyclase
F3Y30_RS18390	COG3300	MHYT domain
F3Y30_RS18400	COG0193	aminoacyl-tRNA hydrolase activity
F3Y30_RS18410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F3Y30_RS18430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F3Y30_RS18435	COG2857	Cytochrome c1
F3Y30_RS18435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F3Y30_RS18450	COG1132	(ABC) transporter
F3Y30_RS18460	COG1132	(ABC) transporter
F3Y30_RS18465	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3Y30_RS18470	COG0431	NADPH-dependent FMN reductase
F3Y30_RS18480	COG1253	flavin adenine dinucleotide binding
F3Y30_RS18490	COG0408	coproporphyrinogen oxidase activity
F3Y30_RS18505	COG0617	tRNA 3'-terminal CCA addition
F3Y30_RS18520	COG0714	Associated with various cellular activities
F3Y30_RS18545	COG0435	Glutathione S-transferase
F3Y30_RS18565	COG1595	DNA-templated transcription, initiation
F3Y30_RS18600	COG0235	Class ii aldolase
F3Y30_RS18605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3Y30_RS18615	COG3842	ATPase activity
F3Y30_RS18620	COG3842	ATPase activity
F3Y30_RS18630	COG1175	transmembrane transport
F3Y30_RS18635	COG1653	transport
F3Y30_RS18645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3Y30_RS18650	COG0740	serine-type endopeptidase activity
F3Y30_RS18660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F3Y30_RS18665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3Y30_RS18670	COG0512	Glutamine amidotransferase of anthranilate synthase
F3Y30_RS18670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3Y30_RS18695	COG2759	Belongs to the formate--tetrahydrofolate ligase family
F3Y30_RS18735	COG1435	thymidine kinase activity
F3Y30_RS18745	COG4176	ABC-type proline glycine betaine transport system permease component
F3Y30_RS18750	COG4175	Glycine betaine
F3Y30_RS18765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3Y30_RS18770	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3Y30_RS18780	COG0366	Alpha amylase catalytic
F3Y30_RS18790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3Y30_RS18795	COG1160	GTP binding
F3Y30_RS18815	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F3Y30_RS18825	COG0024	Methionine aminopeptidase
F3Y30_RS18840	COG4941	Belongs to the sigma-70 factor family
F3Y30_RS18845	COG3795	YCII-related domain
F3Y30_RS18860	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS18895	COG0402	S-adenosylhomocysteine deaminase activity
F3Y30_RS18905	COG2351	hydroxyisourate hydrolase activity
F3Y30_RS18910	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
F3Y30_RS18915	COG3648	Uricase
F3Y30_RS18915	COG3195	allantoin biosynthetic process
F3Y30_RS18925	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3Y30_RS18935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS18940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS18940	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F3Y30_RS18960	COG0513	Belongs to the DEAD box helicase family
F3Y30_RS18970	COG2308	Evidence 4 Homologs of previously reported genes of
F3Y30_RS18980	COG1305	Transglutaminase-like
F3Y30_RS18985	COG0129	dihydroxy-acid dehydratase activity
F3Y30_RS18990	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS19000	COG4214	carbohydrate transport
F3Y30_RS19010	COG4213	ABC transporter substrate-binding protein
F3Y30_RS19035	COG4213	ABC transporter substrate-binding protein
F3Y30_RS19040	COG4214	carbohydrate transport
F3Y30_RS19045	COG1129	ABC transporter
F3Y30_RS19050	COG0668	transmembrane transport
F3Y30_RS19060	COG1216	Glycosyl transferase, family 2
F3Y30_RS19060	COG0463	Glycosyl transferase, family 2
F3Y30_RS19080	COG3727	T/G mismatch-specific endonuclease activity
F3Y30_RS19090	COG0270	DNA (cytosine-5-)-methyltransferase activity
F3Y30_RS19120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3Y30_RS19170	COG1349	DNA-binding transcription factor activity
F3Y30_RS19195	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS19200	COG1175	transmembrane transport
F3Y30_RS19210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F3Y30_RS19215	COG0028	Belongs to the TPP enzyme family
F3Y30_RS19230	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS19240	COG2223	nitrite transmembrane transporter activity
F3Y30_RS19265	COG2226	methyltransferase
F3Y30_RS19270	COG3189	MarR family transcriptional regulator
F3Y30_RS19295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F3Y30_RS19305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3Y30_RS19310	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3Y30_RS19315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F3Y30_RS19325	COG1596	polysaccharide export
F3Y30_RS19350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3Y30_RS19355	COG2197	response regulator
F3Y30_RS19360	COG4585	Histidine kinase
F3Y30_RS19380	COG0489	protein tyrosine kinase activity
F3Y30_RS19380	COG3206	protein involved in exopolysaccharide biosynthesis
F3Y30_RS19410	COG2244	polysaccharide biosynthetic process
F3Y30_RS19420	COG0297	glycogen (starch) synthase activity
F3Y30_RS19425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3Y30_RS19430	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
F3Y30_RS19435	COG1609	Transcriptional regulator
F3Y30_RS19460	COG2346	COG2346, Truncated hemoglobins
F3Y30_RS19500	COG3720	iron ion transport
F3Y30_RS19505	COG4558	Periplasmic binding protein
F3Y30_RS19510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS19515	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F3Y30_RS19530	COG3920	Histidine kinase
F3Y30_RS19530	COG2202	Pas domain
F3Y30_RS19545	COG0784	Response regulator, receiver
F3Y30_RS19580	COG1175	transmembrane transport
F3Y30_RS19590	COG2390	Transcriptional regulator
F3Y30_RS19610	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS19615	COG1309	transcriptional regulator
F3Y30_RS19650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3Y30_RS19655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3Y30_RS19660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3Y30_RS19680	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F3Y30_RS19690	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
F3Y30_RS19705	COG1442	glycosyl transferase family 8
F3Y30_RS19710	COG3755	Protein conserved in bacteria
F3Y30_RS19715	COG0832	Belongs to the urease beta subunit family
F3Y30_RS19720	COG3813	Protein conserved in bacteria
F3Y30_RS19725	COG0831	urea catabolic process
F3Y30_RS19805	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS19865	COG1349	DNA-binding transcription factor activity
F3Y30_RS19870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3Y30_RS19875	COG1335	isochorismatase
F3Y30_RS19880	COG0251	oxidation-reduction process
F3Y30_RS19885	COG2267	carboxylic ester hydrolase activity
F3Y30_RS19890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3Y30_RS19895	COG0346	lactoylglutathione lyase activity
F3Y30_RS19905	COG0346	lactoylglutathione lyase activity
F3Y30_RS19925	COG4774	siderophore transport
F3Y30_RS19930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS19940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3Y30_RS19945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3Y30_RS19955	COG1802	Transcriptional regulator
F3Y30_RS19960	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3Y30_RS19970	COG0725	ABC transporter, periplasmic molybdate-binding protein
F3Y30_RS19980	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F3Y30_RS20010	COG0642	Histidine kinase
F3Y30_RS20040	COG3119	arylsulfatase activity
F3Y30_RS20050	COG0482	sulfurtransferase activity
F3Y30_RS20055	COG2771	luxR family
F3Y30_RS20065	COG2995	paraquat-inducible protein a
F3Y30_RS20115	COG0564	pseudouridine synthase activity
F3Y30_RS20120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3Y30_RS20130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F3Y30_RS20140	COG0840	transmembrane signaling receptor activity
F3Y30_RS20145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3Y30_RS20170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3Y30_RS20175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3Y30_RS20180	COG0037	tRNA processing
F3Y30_RS20190	COG2885	chlorophyll binding
F3Y30_RS20195	COG0823	Involved in the tonB-independent uptake of proteins
F3Y30_RS20215	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
F3Y30_RS20225	COG0824	Thioesterase
F3Y30_RS20245	COG1408	metallophosphoesterase
F3Y30_RS20250	COG2255	four-way junction helicase activity
F3Y30_RS20260	COG0632	four-way junction helicase activity
F3Y30_RS20265	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
F3Y30_RS20270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3Y30_RS20275	COG0217	transcriptional regulatory protein
F3Y30_RS20290	COG1692	metallophosphoesterase
F3Y30_RS20305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3Y30_RS20315	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS20355	COG0126	phosphoglycerate kinase activity
F3Y30_RS20360	COG3588	fructose-bisphosphate aldolase
F3Y30_RS20385	COG0254	rRNA binding
F3Y30_RS20390	COG1132	(ABC) transporter
F3Y30_RS20405	COG0483	inositol monophosphate 1-phosphatase activity
F3Y30_RS20430	COG0640	Transcriptional regulator
F3Y30_RS20445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F3Y30_RS20450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3Y30_RS20455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F3Y30_RS20460	COG0457	Tetratricopeptide repeat
F3Y30_RS20465	COG0469	pyruvate kinase activity
F3Y30_RS20485	COG3750	Belongs to the UPF0335 family
F3Y30_RS20490	COG3108	Peptidase M15
F3Y30_RS20505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3Y30_RS20505	COG0512	Glutamine amidotransferase of anthranilate synthase
F3Y30_RS20535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3Y30_RS20540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3Y30_RS20545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F3Y30_RS20550	COG0156	8-amino-7-oxononanoate synthase activity
F3Y30_RS20555	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F3Y30_RS20575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS20580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3Y30_RS20620	COG5310	Homospermidine synthase
F3Y30_RS20630	COG0737	Belongs to the 5'-nucleotidase family
F3Y30_RS20635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F3Y30_RS20640	COG0330	HflC and HflK could
F3Y30_RS20645	COG1585	Membrane protein implicated in regulation of membrane protease activity
F3Y30_RS20660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3Y30_RS20665	COG2951	lytic endotransglycosylase activity
F3Y30_RS20680	COG0070	glutamate synthase
F3Y30_RS20680	COG0069	glutamate synthase activity
F3Y30_RS20680	COG0067	glutamate synthase
F3Y30_RS20690	COG0583	DNA-binding transcription factor activity
F3Y30_RS20700	COG0071	Belongs to the small heat shock protein (HSP20) family
F3Y30_RS20710	COG0483	inositol monophosphate 1-phosphatase activity
F3Y30_RS20750	COG1566	PFAM secretion protein HlyD family protein
F3Y30_RS20770	COG3932	Exopolysaccharide synthesis, ExoD
F3Y30_RS20775	COG2721	sulfolactate sulfo-lyase activity
F3Y30_RS20780	COG0625	glutathione transferase activity
F3Y30_RS20795	COG0129	dihydroxy-acid dehydratase activity
F3Y30_RS20820	COG2307	Protein conserved in bacteria
F3Y30_RS20820	COG2308	Evidence 4 Homologs of previously reported genes of
F3Y30_RS20835	COG0058	SHG alpha-glucan phosphorylase activity
F3Y30_RS20840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F3Y30_RS20845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F3Y30_RS20850	COG0297	glycogen (starch) synthase activity
F3Y30_RS20855	COG0033	Phosphoglucomutase
F3Y30_RS20860	COG1523	belongs to the glycosyl hydrolase 13 family
F3Y30_RS20875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3Y30_RS20875	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3Y30_RS20885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS20890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3Y30_RS20925	COG5001	Diguanylate cyclase
F3Y30_RS20930	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F3Y30_RS20940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3Y30_RS20945	COG1609	Transcriptional regulator
F3Y30_RS20950	COG1846	Transcriptional regulator
F3Y30_RS20960	COG0523	cobalamin synthesis protein
F3Y30_RS20985	COG3047	cAMP biosynthetic process
F3Y30_RS21005	COG0583	DNA-binding transcription factor activity
F3Y30_RS21035	COG0800	Aldolase
F3Y30_RS21110	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS21135	COG3246	L-lysine catabolic process to acetate
F3Y30_RS21140	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3Y30_RS21165	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F3Y30_RS21170	COG3639	organic phosphonate transmembrane transporter activity
F3Y30_RS21180	COG1902	pentaerythritol trinitrate reductase activity
F3Y30_RS21185	COG0640	Transcriptional regulator
F3Y30_RS21190	COG0154	amidase activity
F3Y30_RS21195	COG0583	DNA-binding transcription factor activity
F3Y30_RS21200	COG0583	DNA-binding transcription factor activity
F3Y30_RS21205	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS21210	COG1764	response to oxidative stress
F3Y30_RS21240	COG0488	(ABC) transporter
F3Y30_RS21245	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F3Y30_RS21250	COG1063	alcohol dehydrogenase
F3Y30_RS21255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3Y30_RS21260	COG3265	gluconokinase activity
F3Y30_RS21265	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS21270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3Y30_RS21275	COG1126	abc transporter atp-binding protein
F3Y30_RS21280	COG1126	abc transporter atp-binding protein
F3Y30_RS21285	COG0765	amino acid transport
F3Y30_RS21305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3Y30_RS21315	COG0765	amino acid transport
F3Y30_RS21320	COG0765	amino acid transport
F3Y30_RS21325	COG4221	oxidoreductase activity
F3Y30_RS21335	COG0436	Aminotransferase
F3Y30_RS21340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F3Y30_RS21345	COG1984	allophanate hydrolase subunit 2
F3Y30_RS21360	COG0439	Biotin carboxylase
F3Y30_RS21365	COG0511	ligase activity, forming carbon-carbon bonds
F3Y30_RS21415	COG3718	enzyme involved in inositol metabolism
F3Y30_RS21420	COG3962	Belongs to the TPP enzyme family
F3Y30_RS21425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3Y30_RS21430	COG1082	Xylose isomerase domain protein TIM barrel
F3Y30_RS21435	COG1082	Xylose isomerase domain protein TIM barrel
F3Y30_RS21440	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS21445	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS21450	COG1082	Xylose isomerase domain protein TIM barrel
F3Y30_RS21455	COG1129	ABC transporter
F3Y30_RS21500	COG0523	cobalamin synthesis protein
F3Y30_RS21510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3Y30_RS21530	COG1501	Belongs to the glycosyl hydrolase 31 family
F3Y30_RS21555	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS21560	COG1175	transmembrane transport
F3Y30_RS21570	COG3842	ATPase activity
F3Y30_RS21575	COG1609	Transcriptional regulator
F3Y30_RS21590	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS21595	COG1175	transmembrane transport
F3Y30_RS21605	COG1609	Transcriptional regulator
F3Y30_RS21630	COG1917	Cupin 2, conserved barrel domain protein
F3Y30_RS21635	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS21645	COG1129	ABC transporter
F3Y30_RS21660	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS21665	COG1802	Transcriptional regulator
F3Y30_RS21675	COG3005	denitrification pathway
F3Y30_RS21685	COG0243	molybdopterin cofactor binding
F3Y30_RS21700	COG4459	periplasmic nitrate reductase
F3Y30_RS21725	COG2151	metal-sulfur cluster biosynthetic enzyme
F3Y30_RS21745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3Y30_RS21755	COG0714	Associated with various cellular activities
F3Y30_RS21760	COG3256	nitric oxide reductase
F3Y30_RS21775	COG1845	cytochrome c oxidase, subunit III
F3Y30_RS21790	COG0826	peptidase U32
F3Y30_RS21795	COG0826	peptidase U32
F3Y30_RS21805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F3Y30_RS21810	COG0163	prenyltransferase activity
F3Y30_RS21925	COG1129	ABC transporter
F3Y30_RS21930	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS21935	COG1879	ABC-type sugar transport system periplasmic component
F3Y30_RS21940	COG1595	DNA-templated transcription, initiation
F3Y30_RS21965	COG0708	Exodeoxyribonuclease III
F3Y30_RS21970	COG2354	Protein conserved in bacteria
F3Y30_RS21985	COG0300	oxidoreductase activity
F3Y30_RS22000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3Y30_RS22020	COG0861	Integral membrane protein TerC family
F3Y30_RS22040	COG1278	Cold shock
F3Y30_RS22050	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS22065	COG0434	BtpA family
F3Y30_RS22095	COG3706	GGDEF domain
F3Y30_RS22110	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS22155	COG3842	ATPase activity
F3Y30_RS22215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3Y30_RS22220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3Y30_RS22225	COG0149	triose-phosphate isomerase activity
F3Y30_RS22235	COG1129	ABC transporter
F3Y30_RS22240	COG1879	ABC-type sugar transport system periplasmic component
F3Y30_RS22245	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS22250	COG3959	Transketolase, thiamine diphosphate binding domain
F3Y30_RS22255	COG3958	Transketolase
F3Y30_RS22260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3Y30_RS22265	COG2390	Transcriptional regulator
F3Y30_RS22270	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS22280	COG4566	intracellular signal transduction
F3Y30_RS22285	COG4191	Histidine kinase
F3Y30_RS22340	COG1376	ErfK ybiS ycfS ynhG family protein
F3Y30_RS22345	COG0583	DNA-binding transcription factor activity
F3Y30_RS22350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F3Y30_RS22350	COG0519	Catalyzes the synthesis of GMP from XMP
F3Y30_RS22355	COG1942	4-Oxalocrotonate Tautomerase
F3Y30_RS22360	COG1794	racemase activity, acting on amino acids and derivatives
F3Y30_RS22380	COG0625	glutathione transferase activity
F3Y30_RS22385	COG1846	Transcriptional regulator
F3Y30_RS22395	COG4948	Mandelate Racemase Muconate Lactonizing
F3Y30_RS22410	COG1475	DNA binding
F3Y30_RS22415	COG1192	Involved in chromosome partitioning
F3Y30_RS22440	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS22445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3Y30_RS22465	COG0346	lactoylglutathione lyase activity
F3Y30_RS22490	COG1879	ABC-type sugar transport system periplasmic component
F3Y30_RS22495	COG1129	ABC transporter
F3Y30_RS22500	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS22520	COG0129	dihydroxy-acid dehydratase activity
F3Y30_RS22525	COG0840	transmembrane signaling receptor activity
F3Y30_RS22545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3Y30_RS22550	COG3842	ATPase activity
F3Y30_RS22555	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS22560	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS22605	COG0789	Transcriptional regulator
F3Y30_RS22620	COG0640	Transcriptional regulator
F3Y30_RS22625	COG1192	Involved in chromosome partitioning
F3Y30_RS22630	COG0436	Aminotransferase
F3Y30_RS22650	COG3842	ATPase activity
F3Y30_RS22655	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS22665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3Y30_RS22695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3Y30_RS22700	COG1177	transmembrane transport
F3Y30_RS22705	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS22725	COG2274	protein secretion by the type I secretion system
F3Y30_RS22745	COG3706	GGDEF domain
F3Y30_RS22750	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS22755	COG1177	transmembrane transport
F3Y30_RS22760	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS22765	COG3842	ATPase activity
F3Y30_RS22785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3Y30_RS22810	COG1177	transmembrane transport
F3Y30_RS22815	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS22820	COG3842	ATPase activity
F3Y30_RS22830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3Y30_RS22835	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS22840	COG1802	Transcriptional regulator
F3Y30_RS22845	COG1320	monovalent cation:proton antiporter activity
F3Y30_RS22850	COG2212	antiporter activity
F3Y30_RS22860	COG0651	ATP synthesis coupled electron transport
F3Y30_RS22865	COG1006	Multisubunit Na H antiporter MnhC subunit
F3Y30_RS22870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3Y30_RS22870	COG2111	Na H antiporter
F3Y30_RS22875	COG3206	protein involved in exopolysaccharide biosynthesis
F3Y30_RS22875	COG0489	protein tyrosine kinase activity
F3Y30_RS22880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3Y30_RS22885	COG1215	transferase activity, transferring glycosyl groups
F3Y30_RS22890	COG1215	transferase activity, transferring glycosyl groups
F3Y30_RS22895	COG1215	transferase activity, transferring glycosyl groups
F3Y30_RS22900	COG0438	transferase activity, transferring glycosyl groups
F3Y30_RS22905	COG2273	Hydrolase Family 16
F3Y30_RS22910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3Y30_RS22915	COG2244	polysaccharide biosynthetic process
F3Y30_RS22920	COG0463	Glycosyl transferase, family 2
F3Y30_RS22925	COG2327	Polysaccharide pyruvyl transferase
F3Y30_RS22930	COG1215	transferase activity, transferring glycosyl groups
F3Y30_RS22945	COG1596	polysaccharide export
F3Y30_RS22950	COG3307	-O-antigen
F3Y30_RS22955	COG0174	glutamine synthetase
F3Y30_RS22960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F3Y30_RS23010	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS23015	COG1177	transmembrane transport
F3Y30_RS23020	COG3842	ATPase activity
F3Y30_RS23045	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS23050	COG1748	Saccharopine dehydrogenase
F3Y30_RS23065	COG1070	Carbohydrate kinase
F3Y30_RS23090	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS23095	COG1879	ABC-type sugar transport system periplasmic component
F3Y30_RS23100	COG1082	Xylose isomerase domain protein TIM barrel
F3Y30_RS23120	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS23125	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
F3Y30_RS23150	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F3Y30_RS23165	COG3685	Protein conserved in bacteria
F3Y30_RS23185	COG1566	PFAM secretion protein HlyD family protein
F3Y30_RS23240	COG2169	Transcriptional regulator
F3Y30_RS23240	COG1917	Cupin 2, conserved barrel domain protein
F3Y30_RS23245	COG4589	Belongs to the CDS family
F3Y30_RS23260	COG2453	phosphatase
F3Y30_RS23260	COG0671	phosphoesterase, PA-phosphatase related
F3Y30_RS23265	COG2267	carboxylic ester hydrolase activity
F3Y30_RS23270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3Y30_RS23285	COG0402	S-adenosylhomocysteine deaminase activity
F3Y30_RS23290	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS23300	COG3845	ABC transporter
F3Y30_RS23305	COG0154	amidase activity
F3Y30_RS23315	COG0579	oxidoreductase
F3Y30_RS23330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS23335	COG0210	DNA helicase
F3Y30_RS23340	COG0174	glutamine synthetase
F3Y30_RS23345	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS23360	COG3962	Belongs to the TPP enzyme family
F3Y30_RS23365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3Y30_RS23375	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS23390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3Y30_RS23395	COG0842	Transport permease protein
F3Y30_RS23395	COG1129	ABC transporter
F3Y30_RS23400	COG0842	Transport permease protein
F3Y30_RS23420	COG1845	cytochrome c oxidase, subunit III
F3Y30_RS23435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3Y30_RS23445	COG1672	PFAM Archaeal ATPase
F3Y30_RS23445	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3Y30_RS23470	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS23480	COG3842	ATPase activity
F3Y30_RS23485	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS23490	COG1175	transmembrane transport
F3Y30_RS23495	COG1653	transport
F3Y30_RS23500	COG1609	Transcriptional regulator
F3Y30_RS23505	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS23510	COG1024	Enoyl-CoA hydratase
F3Y30_RS23525	COG1609	Transcriptional regulator
F3Y30_RS23535	COG0438	transferase activity, transferring glycosyl groups
F3Y30_RS23560	COG0833	amino acid
F3Y30_RS23575	COG4303	Ethanolamine ammonia lyase large subunit
F3Y30_RS23615	COG1063	alcohol dehydrogenase
F3Y30_RS23640	COG3842	ATPase activity
F3Y30_RS23645	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS23660	COG0402	S-adenosylhomocysteine deaminase activity
F3Y30_RS23665	COG1228	amidohydrolase
F3Y30_RS23670	COG2986	histidine ammonia-lyase
F3Y30_RS23680	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F3Y30_RS23685	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3Y30_RS23690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3Y30_RS23705	COG1309	transcriptional regulator
F3Y30_RS23730	COG2226	methyltransferase
F3Y30_RS23735	COG2186	Transcriptional regulator
F3Y30_RS23740	COG0626	cystathionine gamma-synthase activity
F3Y30_RS23755	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS23760	COG3842	ATPase activity
F3Y30_RS23775	COG0183	Belongs to the thiolase family
F3Y30_RS23780	COG1960	acyl-CoA dehydrogenase activity
F3Y30_RS23790	COG0022	dehydrogenase e1 component
F3Y30_RS23805	COG1024	Enoyl-CoA hydratase
F3Y30_RS23820	COG0670	Belongs to the BI1 family
F3Y30_RS23845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F3Y30_RS23850	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3Y30_RS23855	COG2273	Hydrolase Family 16
F3Y30_RS23855	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
F3Y30_RS23860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3Y30_RS23860	COG4651	solute:proton antiporter activity
F3Y30_RS23875	COG1177	transmembrane transport
F3Y30_RS23895	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS23900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3Y30_RS23910	COG2267	carboxylic ester hydrolase activity
F3Y30_RS23935	COG4221	oxidoreductase activity
F3Y30_RS23955	COG1595	DNA-templated transcription, initiation
F3Y30_RS23960	COG3806	Anti-sigma factor
F3Y30_RS23970	COG0535	radical SAM domain protein
F3Y30_RS23975	COG0535	radical SAM domain protein
F3Y30_RS23980	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
F3Y30_RS24055	COG4451	ribulose bisphosphate carboxylase, small
F3Y30_RS24060	COG1850	ribulose-bisphosphate carboxylase activity
F3Y30_RS24075	COG3954	Phosphoribulokinase
F3Y30_RS24080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F3Y30_RS24085	COG0583	DNA-binding transcription factor activity
F3Y30_RS24095	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
F3Y30_RS24100	COG1229	Formylmethanofuran dehydrogenase subunit A
F3Y30_RS24105	COG2154	pterin-4-alpha-carbinolamine dehydratase
F3Y30_RS24115	COG0702	epimerase
F3Y30_RS24130	COG0189	ligase activity
F3Y30_RS24140	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
F3Y30_RS24225	COG0765	amino acid transport
F3Y30_RS24250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3Y30_RS24270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3Y30_RS24280	COG1959	2 iron, 2 sulfur cluster binding
F3Y30_RS24320	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS24325	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS24330	COG1129	ABC transporter
F3Y30_RS24340	COG4521	taurine ABC transporter
F3Y30_RS24350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3Y30_RS24360	COG1129	ABC transporter
F3Y30_RS24365	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS24395	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F3Y30_RS24405	COG1335	isochorismatase
F3Y30_RS24425	COG0583	DNA-binding transcription factor activity
F3Y30_RS24430	COG0346	lactoylglutathione lyase activity
F3Y30_RS24435	COG0400	carboxylic ester hydrolase activity
F3Y30_RS24440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3Y30_RS24450	COG3485	protocatechuate 3,4-dioxygenase
F3Y30_RS24485	COG1454	alcohol dehydrogenase
F3Y30_RS24495	COG0583	DNA-binding transcription factor activity
F3Y30_RS24500	COG4608	Belongs to the ABC transporter superfamily
F3Y30_RS24515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3Y30_RS24520	COG0747	negative chemotaxis
F3Y30_RS24560	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS24565	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS24570	COG3845	ABC transporter
F3Y30_RS24580	COG0019	diaminopimelate decarboxylase activity
F3Y30_RS24590	COG1695	Transcriptional regulator
F3Y30_RS24605	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F3Y30_RS24610	COG2894	cell division
F3Y30_RS24615	COG0850	regulation of cytokinetic process
F3Y30_RS24630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3Y30_RS24635	COG1845	cytochrome c oxidase, subunit III
F3Y30_RS24640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F3Y30_RS24650	COG3842	ATPase activity
F3Y30_RS24660	COG1177	transmembrane transport
F3Y30_RS24665	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3Y30_RS24670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F3Y30_RS24670	COG0519	Catalyzes the synthesis of GMP from XMP
F3Y30_RS24675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS24680	COG0174	glutamine synthetase
F3Y30_RS24705	COG1177	transmembrane transport
F3Y30_RS24710	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS24715	COG3842	ATPase activity
F3Y30_RS24745	COG1609	Transcriptional regulator
F3Y30_RS24750	COG0251	oxidation-reduction process
F3Y30_RS24780	COG3842	ATPase activity
F3Y30_RS24785	COG1177	transmembrane transport
F3Y30_RS24790	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS24830	COG1879	ABC-type sugar transport system periplasmic component
F3Y30_RS24835	COG1129	ABC transporter
F3Y30_RS24840	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS24850	COG2376	Dihydroxyacetone kinase
F3Y30_RS24875	COG1120	ATPase activity
F3Y30_RS24880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS24885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS24890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3Y30_RS24910	COG1215	transferase activity, transferring glycosyl groups
F3Y30_RS24945	COG0022	dehydrogenase e1 component
F3Y30_RS24950	COG1522	sequence-specific DNA binding
F3Y30_RS24955	COG3842	ATPase activity
F3Y30_RS24965	COG1175	transmembrane transport
F3Y30_RS24970	COG1653	transport
F3Y30_RS24980	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS24985	COG1609	Transcriptional regulator
F3Y30_RS25030	COG0745	RESPONSE REGULATOR receiver
F3Y30_RS25035	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F3Y30_RS25040	COG1309	transcriptional regulator
F3Y30_RS25045	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F3Y30_RS25050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3Y30_RS25055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3Y30_RS25060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3Y30_RS25065	COG1082	Xylose isomerase domain protein TIM barrel
F3Y30_RS25065	COG3185	4-Hydroxyphenylpyruvate dioxygenase
F3Y30_RS25080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3Y30_RS25090	COG0657	acetylesterase activity
F3Y30_RS25095	COG0583	DNA-binding transcription factor activity
F3Y30_RS25100	COG2197	response regulator
F3Y30_RS25105	COG1596	polysaccharide export
F3Y30_RS25110	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F3Y30_RS25120	COG1088	dTDP-glucose 4,6-dehydratase activity
F3Y30_RS25135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F3Y30_RS25140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3Y30_RS25155	COG0673	inositol 2-dehydrogenase activity
F3Y30_RS25165	COG2197	response regulator
F3Y30_RS25170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3Y30_RS25190	COG0667	Aldo Keto reductase
F3Y30_RS25205	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS25210	COG1129	ABC transporter
F3Y30_RS25215	COG1879	ABC-type sugar transport system periplasmic component
F3Y30_RS25220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F3Y30_RS25240	COG1802	Transcriptional regulator
F3Y30_RS25255	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS25270	COG1132	(ABC) transporter
F3Y30_RS25275	COG2376	Dihydroxyacetone kinase
F3Y30_RS25280	COG1082	Xylose isomerase domain protein TIM barrel
F3Y30_RS25285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3Y30_RS25295	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS25300	COG1129	ABC transporter
F3Y30_RS25305	COG1879	ABC-type sugar transport system periplasmic component
F3Y30_RS25310	COG1802	Transcriptional regulator
F3Y30_RS25315	COG1177	transmembrane transport
F3Y30_RS25325	COG3842	ATPase activity
F3Y30_RS25335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3Y30_RS25340	COG0583	DNA-binding transcription factor activity
F3Y30_RS25350	COG1070	Carbohydrate kinase
F3Y30_RS25360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3Y30_RS25365	COG0667	Aldo Keto reductase
F3Y30_RS25395	COG3246	L-lysine catabolic process to acetate
F3Y30_RS25415	COG1137	ATPase activity
F3Y30_RS25425	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3Y30_RS25475	COG1129	ABC transporter
F3Y30_RS25480	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS25500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3Y30_RS25515	COG1461	Dihydroxyacetone kinase
F3Y30_RS25520	COG2376	Dihydroxyacetone kinase
F3Y30_RS25530	COG2376	Dihydroxyacetone kinase
F3Y30_RS25535	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS25540	COG1879	ABC-type sugar transport system periplasmic component
F3Y30_RS25545	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS25550	COG1129	ABC transporter
F3Y30_RS25555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3Y30_RS25560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3Y30_RS25570	COG4221	oxidoreductase activity
F3Y30_RS25575	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS25585	COG2186	Transcriptional regulator
F3Y30_RS25590	COG0028	Belongs to the TPP enzyme family
F3Y30_RS25595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS25600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3Y30_RS25625	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS25645	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS25650	COG2086	electron transfer activity
F3Y30_RS25685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3Y30_RS25695	COG0067	glutamate synthase
F3Y30_RS25695	COG0069	glutamate synthase activity
F3Y30_RS25695	COG0070	glutamate synthase
F3Y30_RS25700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F3Y30_RS25715	COG0640	Transcriptional regulator
F3Y30_RS25745	COG4774	siderophore transport
F3Y30_RS25755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F3Y30_RS25760	COG2814	Major facilitator Superfamily
F3Y30_RS25765	COG1028	Short-chain dehydrogenase reductase Sdr
F3Y30_RS25785	COG3485	protocatechuate 3,4-dioxygenase
F3Y30_RS25825	COG3842	ATPase activity
F3Y30_RS25835	COG0395	ABC-type sugar transport system, permease component
F3Y30_RS25840	COG1175	transmembrane transport
F3Y30_RS25855	COG1846	Transcriptional regulator
F3Y30_RS25895	COG1012	belongs to the aldehyde dehydrogenase family
F3Y30_RS25920	COG3842	ATPase activity
F3Y30_RS25925	COG1177	transmembrane transport
F3Y30_RS25930	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3Y30_RS25950	COG1609	Transcriptional regulator
F3Y30_RS25970	COG2086	electron transfer activity
F3Y30_RS25980	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3Y30_RS25980	COG1902	pentaerythritol trinitrate reductase activity
F3Y30_RS25990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3Y30_RS26000	COG4176	ABC-type proline glycine betaine transport system permease component
F3Y30_RS26005	COG3448	diguanylate cyclase activity
F3Y30_RS26005	COG4175	Glycine betaine
F3Y30_RS26010	COG1902	pentaerythritol trinitrate reductase activity
F3Y30_RS26010	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3Y30_RS26015	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3Y30_RS26050	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3Y30_RS26075	COG3246	L-lysine catabolic process to acetate
F3Y30_RS26080	COG1250	3-hydroxyacyl-CoA dehydrogenase