locus-tag	class	description
BSY16_RS00105	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSY16_RS00160	COG1121	(ABC) transporter
BSY16_RS00165	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BSY16_RS00170	COG2195	Cleaves the N-terminal amino acid of tripeptides
BSY16_RS00175	COG0490	domain, Protein
BSY16_RS00175	COG0471	metal ion transport
BSY16_RS00185	COG1863	multisubunit Na H antiporter MnhE subunit
BSY16_RS00190	COG2212	antiporter activity
BSY16_RS00205	COG2111	Na H antiporter
BSY16_RS00205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSY16_RS00210	COG1006	Multisubunit Na H antiporter MnhC subunit
BSY16_RS00215	COG0651	ATP synthesis coupled electron transport
BSY16_RS00225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY16_RS00230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY16_RS00260	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS00295	COG0154	amidase activity
BSY16_RS00305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS00310	COG1414	Transcriptional regulator
BSY16_RS00325	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY16_RS00330	COG1177	transmembrane transport
BSY16_RS00335	COG3842	ATPase activity
BSY16_RS00345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS00370	COG1595	DNA-templated transcription, initiation
BSY16_RS00380	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSY16_RS00385	COG1802	Transcriptional regulator
BSY16_RS00400	COG0400	carboxylic ester hydrolase activity
BSY16_RS00410	COG0346	lactoylglutathione lyase activity
BSY16_RS00415	COG0840	transmembrane signaling receptor activity
BSY16_RS00420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY16_RS00430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY16_RS00475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS00480	COG4311	Sarcosine oxidase, delta subunit
BSY16_RS00485	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY16_RS00485	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSY16_RS00500	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS00535	COG2205	protein histidine kinase activity
BSY16_RS00535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY16_RS00545	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS00555	COG0411	ABC transporter
BSY16_RS00575	COG0831	urea catabolic process
BSY16_RS00580	COG3813	Protein conserved in bacteria
BSY16_RS00585	COG0832	Belongs to the urease beta subunit family
BSY16_RS00590	COG3755	Protein conserved in bacteria
BSY16_RS00595	COG1442	glycosyl transferase family 8
BSY16_RS00600	COG0804	urea catabolic process
BSY16_RS00610	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BSY16_RS00615	COG0830	nickel cation binding
BSY16_RS00635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY16_RS00640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY16_RS00645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY16_RS00685	COG1309	transcriptional regulator
BSY16_RS00700	COG3932	Exopolysaccharide synthesis, ExoD
BSY16_RS00720	COG0493	'glutamate synthase
BSY16_RS00725	COG2390	Transcriptional regulator
BSY16_RS00735	COG1175	transmembrane transport
BSY16_RS00740	COG0395	ABC-type sugar transport system, permease component
BSY16_RS00760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSY16_RS00770	COG0784	Response regulator, receiver
BSY16_RS00780	COG2202	Pas domain
BSY16_RS00780	COG3920	Histidine kinase
BSY16_RS00795	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BSY16_RS00800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY16_RS00805	COG4558	Periplasmic binding protein
BSY16_RS00810	COG3720	iron ion transport
BSY16_RS00850	COG2346	COG2346, Truncated hemoglobins
BSY16_RS00870	COG0673	inositol 2-dehydrogenase activity
BSY16_RS00875	COG1609	Transcriptional regulator
BSY16_RS00890	COG0456	acetyltransferase
BSY16_RS00905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY16_RS00910	COG1845	cytochrome c oxidase, subunit III
BSY16_RS00915	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSY16_RS00925	COG0300	oxidoreductase activity
BSY16_RS00950	COG4974	Belongs to the 'phage' integrase family
BSY16_RS00990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSY16_RS00995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSY16_RS01010	COG1129	ABC transporter
BSY16_RS01015	COG4214	carbohydrate transport
BSY16_RS01020	COG4213	ABC transporter substrate-binding protein
BSY16_RS01030	COG0673	inositol 2-dehydrogenase activity
BSY16_RS01035	COG4211	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS01040	COG1129	ABC transporter
BSY16_RS01075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSY16_RS01105	COG4214	carbohydrate transport
BSY16_RS01115	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS01120	COG0129	dihydroxy-acid dehydratase activity
BSY16_RS01130	COG1305	Transglutaminase-like
BSY16_RS01140	COG2308	Evidence 4 Homologs of previously reported genes of
BSY16_RS01150	COG0513	Belongs to the DEAD box helicase family
BSY16_RS01155	COG4335	DNA alkylation repair
BSY16_RS01165	COG5598	trimethylamine methyltransferase
BSY16_RS01175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS01175	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BSY16_RS01195	COG3648	Uricase
BSY16_RS01195	COG3195	allantoin biosynthetic process
BSY16_RS01200	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BSY16_RS01205	COG2351	hydroxyisourate hydrolase activity
BSY16_RS01210	COG0402	S-adenosylhomocysteine deaminase activity
BSY16_RS01230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY16_RS01250	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS01255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSY16_RS01275	COG3795	YCII-related domain
BSY16_RS01280	COG4941	Belongs to the sigma-70 factor family
BSY16_RS01295	COG0024	Methionine aminopeptidase
BSY16_RS01305	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BSY16_RS01325	COG1160	GTP binding
BSY16_RS01330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY16_RS01335	COG0583	DNA-binding transcription factor activity
BSY16_RS01340	COG0601	transmembrane transport
BSY16_RS01345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY16_RS01365	COG1473	amidohydrolase
BSY16_RS01375	COG0366	Alpha amylase catalytic
BSY16_RS01390	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BSY16_RS01405	COG3011	Protein conserved in bacteria
BSY16_RS01415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSY16_RS01430	COG4175	Glycine betaine
BSY16_RS01445	COG1435	thymidine kinase activity
BSY16_RS01495	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BSY16_RS01515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSY16_RS01515	COG0512	Glutamine amidotransferase of anthranilate synthase
BSY16_RS01520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSY16_RS01525	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BSY16_RS01535	COG0740	serine-type endopeptidase activity
BSY16_RS01540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY16_RS01555	COG1595	DNA-templated transcription, initiation
BSY16_RS01575	COG0435	Glutathione S-transferase
BSY16_RS01615	COG0714	Associated with various cellular activities
BSY16_RS01630	COG0617	tRNA 3'-terminal CCA addition
BSY16_RS01645	COG0408	coproporphyrinogen oxidase activity
BSY16_RS01665	COG1253	flavin adenine dinucleotide binding
BSY16_RS01685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSY16_RS01690	COG1132	(ABC) transporter
BSY16_RS01695	COG1132	(ABC) transporter
BSY16_RS01710	COG2857	Cytochrome c1
BSY16_RS01710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSY16_RS01715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSY16_RS01740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSY16_RS01760	COG0193	aminoacyl-tRNA hydrolase activity
BSY16_RS01770	COG3300	MHYT domain
BSY16_RS01770	COG5001	Diguanylate cyclase
BSY16_RS01775	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSY16_RS01785	COG3135	benzoate transporter
BSY16_RS01795	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS01810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSY16_RS01835	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSY16_RS01855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSY16_RS01865	COG2205	protein histidine kinase activity
BSY16_RS01870	COG0745	RESPONSE REGULATOR receiver
BSY16_RS01875	COG1846	Transcriptional regulator
BSY16_RS01895	COG1522	sequence-specific DNA binding
BSY16_RS01900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY16_RS01910	COG1278	Cold shock
BSY16_RS01920	COG2133	pyrroloquinoline quinone binding
BSY16_RS01935	COG0436	Aminotransferase
BSY16_RS01945	COG0387	Pfam Sodium calcium exchanger
BSY16_RS01955	COG1902	pentaerythritol trinitrate reductase activity
BSY16_RS01965	COG0583	DNA-binding transcription factor activity
BSY16_RS01970	COG0492	ferredoxin-NADP+ reductase activity
BSY16_RS01975	COG1522	sequence-specific DNA binding
BSY16_RS01985	COG0438	transferase activity, transferring glycosyl groups
BSY16_RS01995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSY16_RS02010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY16_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS02030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSY16_RS02065	COG2321	neutral zinc metallopeptidase
BSY16_RS02075	COG0667	Aldo Keto reductase
BSY16_RS02080	COG0583	DNA-binding transcription factor activity
BSY16_RS02090	COG0534	Mate efflux family protein
BSY16_RS02100	COG0505	Belongs to the CarA family
BSY16_RS02115	COG0358	DNA primase activity
BSY16_RS02125	COG0514	ATP-dependent DNA helicase (RecQ)
BSY16_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS02140	COG2226	methyltransferase
BSY16_RS02155	COG1063	alcohol dehydrogenase
BSY16_RS02165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY16_RS02170	COG2273	Hydrolase Family 16
BSY16_RS02170	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BSY16_RS02180	COG5507	3-demethylubiquinone-9 3-methyltransferase
BSY16_RS02185	COG0432	Pfam Uncharacterised protein family UPF0047
BSY16_RS02200	COG2968	Membrane
BSY16_RS02210	COG0582	viral genome integration into host DNA
BSY16_RS02255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS02270	COG4608	Belongs to the ABC transporter superfamily
BSY16_RS02275	COG0444	Belongs to the ABC transporter superfamily
BSY16_RS02285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY16_RS02290	COG0747	negative chemotaxis
BSY16_RS02295	COG2267	carboxylic ester hydrolase activity
BSY16_RS02300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSY16_RS02305	COG0583	DNA-binding transcription factor activity
BSY16_RS02310	COG3239	Fatty acid desaturase
BSY16_RS02325	COG1278	Cold shock
BSY16_RS02355	COG0642	Histidine kinase
BSY16_RS02370	COG0784	Response regulator, receiver
BSY16_RS02370	COG4191	Histidine kinase
BSY16_RS02380	COG1840	ABC-type Fe3 transport system, periplasmic component
BSY16_RS02385	COG1840	ABC-type Fe3 transport system, periplasmic component
BSY16_RS02395	COG3842	ATPase activity
BSY16_RS02400	COG0483	inositol monophosphate 1-phosphatase activity
BSY16_RS02415	COG1522	sequence-specific DNA binding
BSY16_RS02440	COG2223	nitrite transmembrane transporter activity
BSY16_RS02460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY16_RS02465	COG4597	amino acid ABC transporter
BSY16_RS02470	COG0765	amino acid transport
BSY16_RS02475	COG0402	S-adenosylhomocysteine deaminase activity
BSY16_RS02480	COG4191	Histidine kinase
BSY16_RS02500	COG2972	Histidine kinase
BSY16_RS02500	COG0745	RESPONSE REGULATOR receiver
BSY16_RS02505	COG3279	Response regulator of the LytR AlgR family
BSY16_RS02515	COG1215	transferase activity, transferring glycosyl groups
BSY16_RS02540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BSY16_RS02550	COG4208	sulfate ABC transporter
BSY16_RS02555	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSY16_RS02565	COG2204	response regulator
BSY16_RS02570	COG4191	Histidine kinase
BSY16_RS02575	COG2223	nitrite transmembrane transporter activity
BSY16_RS02580	COG1252	NADH dehydrogenase
BSY16_RS02595	COG0583	DNA-binding transcription factor activity
BSY16_RS02615	COG1522	sequence-specific DNA binding
BSY16_RS02620	COG1335	isochorismatase
BSY16_RS02640	COG4774	siderophore transport
BSY16_RS02655	COG1177	transmembrane transport
BSY16_RS02660	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY16_RS02665	COG3842	ATPase activity
BSY16_RS02670	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BSY16_RS02680	COG0583	DNA-binding transcription factor activity
BSY16_RS02685	COG0657	acetylesterase activity
BSY16_RS02705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY16_RS02715	COG0747	negative chemotaxis
BSY16_RS02730	COG1960	acyl-CoA dehydrogenase activity
BSY16_RS02735	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY16_RS02735	COG0824	Thioesterase
BSY16_RS02740	COG3246	L-lysine catabolic process to acetate
BSY16_RS02760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSY16_RS02775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BSY16_RS02800	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS02805	COG1177	transmembrane transport
BSY16_RS02820	COG3842	ATPase activity
BSY16_RS02825	COG2197	response regulator
BSY16_RS02830	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSY16_RS02835	COG3842	ATPase activity
BSY16_RS02870	COG0174	glutamine synthetase
BSY16_RS02885	COG1192	Involved in chromosome partitioning
BSY16_RS02895	COG0840	transmembrane signaling receptor activity
BSY16_RS02905	COG1376	ErfK ybiS ycfS ynhG family protein
BSY16_RS02920	COG0028	Belongs to the TPP enzyme family
BSY16_RS02925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY16_RS02955	COG2226	methyltransferase
BSY16_RS02960	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BSY16_RS02970	COG0697	spore germination
BSY16_RS02990	COG5001	Diguanylate cyclase
BSY16_RS03015	COG1280	lysine exporter protein (LysE YggA)
BSY16_RS03025	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BSY16_RS03030	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSY16_RS03050	COG2001	Belongs to the MraZ family
BSY16_RS03055	COG0275	rRNA processing
BSY16_RS03070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSY16_RS03080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSY16_RS03085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSY16_RS03095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSY16_RS03100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSY16_RS03105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSY16_RS03110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BSY16_RS03115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BSY16_RS03120	COG0477	Major facilitator Superfamily
BSY16_RS03125	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSY16_RS03130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSY16_RS03135	COG0849	cell division
BSY16_RS03140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSY16_RS03150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSY16_RS03155	COG0497	DNA recombination
BSY16_RS03160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSY16_RS03165	COG0739	heme binding
BSY16_RS03165	COG0741	lytic transglycosylase activity
BSY16_RS03165	COG1196	nuclear chromosome segregation
BSY16_RS03180	COG0513	Belongs to the DEAD box helicase family
BSY16_RS03185	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSY16_RS03190	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSY16_RS03205	COG0006	proline dipeptidase activity
BSY16_RS03215	COG2264	protein methyltransferase activity
BSY16_RS03220	COG1999	signal sequence binding
BSY16_RS03230	COG0835	chemotaxis
BSY16_RS03245	COG3142	Participates in the control of copper homeostasis
BSY16_RS03255	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BSY16_RS03260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSY16_RS03265	COG2188	Transcriptional regulator
BSY16_RS03270	COG2971	BadF BadG BcrA BcrD
BSY16_RS03275	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BSY16_RS03285	COG1175	transmembrane transport
BSY16_RS03290	COG0395	ABC-type sugar transport system, permease component
BSY16_RS03295	COG0673	inositol 2-dehydrogenase activity
BSY16_RS03305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY16_RS03310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY16_RS03325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY16_RS03345	COG1309	transcriptional regulator
BSY16_RS03360	COG3842	ATPase activity
BSY16_RS03365	COG1177	transmembrane transport
BSY16_RS03370	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY16_RS03375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSY16_RS03380	COG1686	Belongs to the peptidase S11 family
BSY16_RS03385	COG4638	Rieske (2fe-2S)
BSY16_RS03420	COG0154	amidase activity
BSY16_RS03435	COG0210	DNA helicase
BSY16_RS03455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY16_RS03460	COG0277	FAD linked oxidase domain protein
BSY16_RS03490	COG2203	Gaf domain
BSY16_RS03490	COG3706	GGDEF domain
BSY16_RS03490	COG4251	negative regulation of phosphorylation
BSY16_RS03490	COG5001	Diguanylate cyclase
BSY16_RS03500	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BSY16_RS03510	COG0330	HflC and HflK could
BSY16_RS03515	COG0330	HflC and HflK could
BSY16_RS03530	COG0560	Phosphoserine phosphatase
BSY16_RS03535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSY16_RS03545	COG0028	Belongs to the TPP enzyme family
BSY16_RS03550	COG0440	acetolactate synthase activity
BSY16_RS03555	COG0656	L-ascorbic acid biosynthetic process
BSY16_RS03560	COG1280	lysine exporter protein (LysE YggA)
BSY16_RS03565	COG3180	Ammonia monooxygenase
BSY16_RS03570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSY16_RS03585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BSY16_RS03595	COG1733	regulation of RNA biosynthetic process
BSY16_RS03600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY16_RS03605	COG1846	Transcriptional regulator
BSY16_RS03605	COG0456	acetyltransferase
BSY16_RS03610	COG1794	racemase activity, acting on amino acids and derivatives
BSY16_RS03615	COG1522	sequence-specific DNA binding
BSY16_RS03620	COG1278	Cold shock
BSY16_RS03650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSY16_RS03655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSY16_RS03660	COG4187	Peptidase family M20/M25/M40
BSY16_RS03680	COG0384	phenazine biosynthesis protein PhzF
BSY16_RS03700	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BSY16_RS03700	COG3264	Mechanosensitive ion channel
BSY16_RS03710	COG0745	RESPONSE REGULATOR receiver
BSY16_RS03740	COG0583	DNA-binding transcription factor activity
BSY16_RS03765	COG0646	methionine synthase
BSY16_RS03765	COG1410	methionine synthase
BSY16_RS03785	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSY16_RS03800	COG5012	cobalamin binding
BSY16_RS03815	COG5598	trimethylamine methyltransferase
BSY16_RS03830	COG1595	DNA-templated transcription, initiation
BSY16_RS03835	COG2304	oxidoreductase activity
BSY16_RS03845	COG0583	DNA-binding transcription factor activity
BSY16_RS03860	COG0436	Aminotransferase
BSY16_RS03875	COG1410	methionine synthase
BSY16_RS03875	COG0646	methionine synthase
BSY16_RS03880	COG4175	Glycine betaine
BSY16_RS03880	COG0517	IMP dehydrogenase activity
BSY16_RS03885	COG4176	ABC-type proline glycine betaine transport system permease component
BSY16_RS03980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSY16_RS03985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSY16_RS03990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSY16_RS04000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSY16_RS04045	COG3706	GGDEF domain
BSY16_RS04080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BSY16_RS04085	COG2814	Major facilitator Superfamily
BSY16_RS04100	COG1175	transmembrane transport
BSY16_RS04105	COG0395	ABC-type sugar transport system, permease component
BSY16_RS04110	COG3842	ATPase activity
BSY16_RS04115	COG3250	beta-galactosidase activity
BSY16_RS04125	COG0673	inositol 2-dehydrogenase activity
BSY16_RS04130	COG0667	Aldo Keto reductase
BSY16_RS04135	COG3507	Belongs to the glycosyl hydrolase 43 family
BSY16_RS04140	COG0523	cobalamin synthesis protein
BSY16_RS04150	COG1121	(ABC) transporter
BSY16_RS04155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSY16_RS04170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSY16_RS04175	COG0484	heat shock protein binding
BSY16_RS04190	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BSY16_RS04195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BSY16_RS04205	COG2084	Dehydrogenase
BSY16_RS04215	COG1522	sequence-specific DNA binding
BSY16_RS04220	COG1573	uracil-dna glycosylase
BSY16_RS04230	COG2205	protein histidine kinase activity
BSY16_RS04230	COG2202	Pas domain
BSY16_RS04245	COG5425	PFAM Usg family protein
BSY16_RS04260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY16_RS04275	COG1763	Mo-molybdopterin cofactor biosynthetic process
BSY16_RS04280	COG0746	molybdenum cofactor guanylyltransferase activity
BSY16_RS04290	COG0840	transmembrane signaling receptor activity
BSY16_RS04300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSY16_RS04345	COG1388	LysM domain
BSY16_RS04345	COG1376	ErfK ybiS ycfS ynhG family protein
BSY16_RS04350	COG3706	GGDEF domain
BSY16_RS04355	COG0114	fumarate hydratase activity
BSY16_RS04360	COG2989	Protein conserved in bacteria
BSY16_RS04370	COG0546	phosphoglycolate phosphatase activity
BSY16_RS04375	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BSY16_RS04400	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BSY16_RS04425	COG1368	sulfuric ester hydrolase activity
BSY16_RS04440	COG0823	Involved in the tonB-independent uptake of proteins
BSY16_RS04450	COG0778	Nitroreductase
BSY16_RS04465	COG0488	(ABC) transporter
BSY16_RS04470	COG0625	glutathione transferase activity
BSY16_RS04475	COG1733	regulation of RNA biosynthetic process
BSY16_RS04480	COG0281	malic enzyme
BSY16_RS04480	COG0280	phosphate acetyltransferase
BSY16_RS04490	COG2814	Major facilitator Superfamily
BSY16_RS04495	COG4948	Mandelate Racemase Muconate Lactonizing
BSY16_RS04500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSY16_RS04505	COG1127	ABC transporter
BSY16_RS04515	COG3218	ABC-type transport auxiliary lipoprotein component
BSY16_RS04515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BSY16_RS04535	COG0633	Ferredoxin
BSY16_RS04540	COG0492	ferredoxin-NADP+ reductase activity
BSY16_RS04550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSY16_RS04560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSY16_RS04570	COG3768	UPF0283 membrane protein
BSY16_RS04575	COG3106	COG3106 Predicted ATPase
BSY16_RS04585	COG3300	MHYT domain
BSY16_RS04585	COG5001	Diguanylate cyclase
BSY16_RS04610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSY16_RS04620	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BSY16_RS04635	COG1058	Belongs to the CinA family
BSY16_RS04635	COG1546	Belongs to the CinA family
BSY16_RS04640	COG0655	NAD(P)H dehydrogenase (quinone) activity
BSY16_RS04660	COG0306	phosphate transporter
BSY16_RS04665	COG1392	Phosphate transport regulator
BSY16_RS04675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSY16_RS04680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSY16_RS04690	COG3706	GGDEF domain
BSY16_RS04705	COG1522	sequence-specific DNA binding
BSY16_RS04710	COG0686	Belongs to the AlaDH PNT family
BSY16_RS04730	COG2897	thiosulfate sulfurtransferase activity
BSY16_RS04735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSY16_RS04745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSY16_RS04785	COG3685	Protein conserved in bacteria
BSY16_RS04880	COG0582	viral genome integration into host DNA
BSY16_RS05000	COG0848	biopolymer transport protein
BSY16_RS05010	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSY16_RS05025	COG0525	valine-tRNA ligase activity
BSY16_RS05035	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BSY16_RS05045	COG0316	Belongs to the HesB IscA family
BSY16_RS05050	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BSY16_RS05055	COG0018	arginyl-trna synthetase
BSY16_RS05065	COG1472	Belongs to the glycosyl hydrolase 3 family
BSY16_RS05070	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BSY16_RS05075	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSY16_RS05085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSY16_RS05090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSY16_RS05095	COG0805	protein transport
BSY16_RS05100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSY16_RS05105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BSY16_RS05110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSY16_RS05125	COG4977	sequence-specific DNA binding
BSY16_RS05150	COG1862	Preprotein translocase
BSY16_RS05175	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BSY16_RS05210	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSY16_RS05225	COG0187	DNA topoisomerase II activity
BSY16_RS05235	COG0149	triose-phosphate isomerase activity
BSY16_RS05240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSY16_RS05245	COG0504	CTP synthase activity
BSY16_RS05255	COG1309	transcriptional regulator
BSY16_RS05270	COG4977	sequence-specific DNA binding
BSY16_RS05275	COG0562	UDP-galactopyranose mutase
BSY16_RS05285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BSY16_RS05290	COG0148	phosphopyruvate hydratase activity
BSY16_RS05300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSY16_RS05305	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY16_RS05305	COG0022	dehydrogenase e1 component
BSY16_RS05310	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY16_RS05320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY16_RS05325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSY16_RS05335	COG2867	negative regulation of translational initiation
BSY16_RS05345	COG1058	Belongs to the CinA family
BSY16_RS05345	COG1546	Belongs to the CinA family
BSY16_RS05350	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSY16_RS05350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSY16_RS05360	COG3852	Histidine kinase
BSY16_RS05365	COG2204	response regulator
BSY16_RS05370	COG5000	phosphorelay sensor kinase activity
BSY16_RS05375	COG2204	response regulator
BSY16_RS05380	COG0569	domain protein
BSY16_RS05385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSY16_RS05390	COG1923	regulation of RNA biosynthetic process
BSY16_RS05395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSY16_RS05400	COG3956	TIGRFAM MazG family protein
BSY16_RS05410	COG1648	precorrin-2 dehydrogenase activity
BSY16_RS05410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSY16_RS05420	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSY16_RS05440	COG0346	lactoylglutathione lyase activity
BSY16_RS05460	COG0583	DNA-binding transcription factor activity
BSY16_RS05465	COG3845	ABC transporter
BSY16_RS05470	COG1079	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS05475	COG4603	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS05505	COG0583	DNA-binding transcription factor activity
BSY16_RS05510	COG2233	PERMEase
BSY16_RS05525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSY16_RS05530	COG0523	cobalamin synthesis protein
BSY16_RS05545	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BSY16_RS05550	COG0163	prenyltransferase activity
BSY16_RS05555	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BSY16_RS05570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSY16_RS05575	COG2010	Cytochrome c
BSY16_RS05600	COG0315	cyclic pyranopterin monophosphate synthase activity
BSY16_RS05605	COG0134	indole-3-glycerol-phosphate synthase activity
BSY16_RS05610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSY16_RS05625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSY16_RS05630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSY16_RS05650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BSY16_RS05660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSY16_RS05685	COG2186	Transcriptional regulator
BSY16_RS05690	COG4651	solute:proton antiporter activity
BSY16_RS05690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSY16_RS05735	COG0747	negative chemotaxis
BSY16_RS05740	COG0601	transmembrane transport
BSY16_RS05745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY16_RS05750	COG0444	Belongs to the ABC transporter superfamily
BSY16_RS05785	COG0640	Transcriptional regulator
BSY16_RS05800	COG0431	NADPH-dependent FMN reductase
BSY16_RS05805	COG2095	MarC family integral membrane protein
BSY16_RS05810	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSY16_RS05815	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSY16_RS05835	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BSY16_RS05840	COG0343	queuine tRNA-ribosyltransferase activity
BSY16_RS05865	COG1126	abc transporter atp-binding protein
BSY16_RS05870	COG0765	amino acid transport
BSY16_RS05875	COG4597	amino acid ABC transporter
BSY16_RS05880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY16_RS05885	COG0626	cystathionine gamma-synthase activity
BSY16_RS05900	COG0596	Alpha beta hydrolase
BSY16_RS05905	COG1045	serine acetyltransferase
BSY16_RS05920	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSY16_RS05945	COG0537	adenosine 5'-monophosphoramidase activity
BSY16_RS05970	COG0052	Belongs to the universal ribosomal protein uS2 family
BSY16_RS05975	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSY16_RS05980	COG0528	UMP kinase activity
BSY16_RS05985	COG0233	cytoplasmic translational termination
BSY16_RS05990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSY16_RS06000	COG0750	zinc metalloprotease
BSY16_RS06010	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY16_RS06015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSY16_RS06020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY16_RS06025	COG3494	Protein of unknown function (DUF1009)
BSY16_RS06030	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY16_RS06035	COG0372	Belongs to the citrate synthase family
BSY16_RS06045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSY16_RS06055	COG0785	Cytochrome C biogenesis protein
BSY16_RS06060	COG0679	Auxin Efflux Carrier
BSY16_RS06065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY16_RS06070	COG1183	phosphatidylcholine synthase activity
BSY16_RS06080	COG3845	ABC transporter
BSY16_RS06085	COG4603	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS06090	COG1079	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS06115	COG0174	glutamine synthetase
BSY16_RS06120	COG0347	Belongs to the P(II) protein family
BSY16_RS06125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSY16_RS06125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSY16_RS06145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSY16_RS06150	COG0629	single-stranded DNA binding
BSY16_RS06165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BSY16_RS06175	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSY16_RS06190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSY16_RS06195	COG0084	hydrolase, TatD family'
BSY16_RS06200	COG0321	lipoyl(octanoyl) transferase activity
BSY16_RS06200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BSY16_RS06205	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSY16_RS06230	COG1278	Cold shock
BSY16_RS06270	COG0436	Aminotransferase
BSY16_RS06280	COG3243	poly(R)-hydroxyalkanoic acid synthase
BSY16_RS06285	COG1489	DNA binding
BSY16_RS06290	COG0024	Methionine aminopeptidase
BSY16_RS06295	COG2003	Belongs to the UPF0758 family
BSY16_RS06340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSY16_RS06350	COG2890	protein-(glutamine-N5) methyltransferase activity
BSY16_RS06375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSY16_RS06385	COG0302	gtp cyclohydrolase
BSY16_RS06390	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSY16_RS06395	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSY16_RS06430	COG1686	Belongs to the peptidase S11 family
BSY16_RS06455	COG1760	l-serine dehydratase
BSY16_RS06480	COG2239	Acts as a magnesium transporter
BSY16_RS06485	COG0242	peptide deformylase activity
BSY16_RS06495	COG0321	lipoyl(octanoyl) transferase activity
BSY16_RS06505	COG4770	biotin carboxylase activity
BSY16_RS06520	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BSY16_RS06530	COG1671	Belongs to the UPF0178 family
BSY16_RS06540	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BSY16_RS06545	COG2076	Multidrug Resistance protein
BSY16_RS06550	COG2259	Doxx family
BSY16_RS06555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY16_RS06570	COG0546	phosphoglycolate phosphatase activity
BSY16_RS06575	COG0564	pseudouridine synthase activity
BSY16_RS06590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY16_RS06595	COG0509	glycine decarboxylation via glycine cleavage system
BSY16_RS06600	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY16_RS06600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY16_RS06610	COG4251	negative regulation of phosphorylation
BSY16_RS06615	COG0316	Belongs to the HesB IscA family
BSY16_RS06620	COG2151	metal-sulfur cluster biosynthetic enzyme
BSY16_RS06625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSY16_RS06630	COG0719	Fe-S assembly protein
BSY16_RS06635	COG0396	ATPase activity
BSY16_RS06645	COG0719	Fe-S assembly protein
BSY16_RS06650	COG1104	cysteine desulfurase activity
BSY16_RS06655	COG2945	thiolester hydrolase activity
BSY16_RS06665	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BSY16_RS06670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSY16_RS06680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSY16_RS06685	COG2833	Protein of unknown function (DUF455)
BSY16_RS06690	COG0739	heme binding
BSY16_RS06695	COG0513	Belongs to the DEAD box helicase family
BSY16_RS06705	COG4206	TonB-dependent receptor
BSY16_RS06705	COG1629	transport
BSY16_RS06715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSY16_RS06720	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BSY16_RS06740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY16_RS06750	COG3191	aminopeptidase activity
BSY16_RS06770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSY16_RS06800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSY16_RS06805	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSY16_RS06815	COG0047	phosphoribosylformylglycinamidine synthase activity
BSY16_RS06830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSY16_RS06835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSY16_RS06855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BSY16_RS06860	COG2814	Major facilitator Superfamily
BSY16_RS06865	COG0483	inositol monophosphate 1-phosphatase activity
BSY16_RS06870	COG0037	tRNA processing
BSY16_RS06875	COG2066	Belongs to the glutaminase family
BSY16_RS06880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSY16_RS06890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSY16_RS06895	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BSY16_RS06905	COG0538	isocitrate dehydrogenase activity
BSY16_RS06910	COG0625	glutathione transferase activity
BSY16_RS06920	COG3706	GGDEF domain
BSY16_RS06925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSY16_RS06930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSY16_RS06940	COG2313	pseudouridylate synthase activity
BSY16_RS06945	COG0842	Transport permease protein
BSY16_RS06950	COG1131	(ABC) transporter
BSY16_RS06955	COG0730	response to heat
BSY16_RS06960	COG0625	glutathione transferase activity
BSY16_RS07000	COG5001	Diguanylate cyclase
BSY16_RS07010	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSY16_RS07040	COG0556	nucleotide-excision repair
BSY16_RS07065	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY16_RS07065	COG0596	Alpha beta hydrolase
BSY16_RS07080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSY16_RS07085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSY16_RS07090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSY16_RS07095	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BSY16_RS07100	COG0203	ribosomal protein L17
BSY16_RS07105	COG0202	RNA polymerase activity
BSY16_RS07110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSY16_RS07115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSY16_RS07120	COG0563	adenylate kinase activity
BSY16_RS07130	COG0200	Binds to the 23S rRNA
BSY16_RS07135	COG1841	ribosomal large subunit assembly
BSY16_RS07140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSY16_RS07145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSY16_RS07150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSY16_RS07155	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSY16_RS07160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSY16_RS07165	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSY16_RS07170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BSY16_RS07175	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSY16_RS07180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSY16_RS07185	COG0255	Belongs to the universal ribosomal protein uL29 family
BSY16_RS07190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSY16_RS07195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSY16_RS07200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSY16_RS07205	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSY16_RS07210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSY16_RS07215	COG0089	rRNA binding
BSY16_RS07220	COG0088	Forms part of the polypeptide exit tunnel
BSY16_RS07225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSY16_RS07230	COG0051	transcription antitermination factor activity, RNA binding
BSY16_RS07235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSY16_RS07240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSY16_RS07245	COG0049	tRNA binding
BSY16_RS07250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSY16_RS07270	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSY16_RS07275	COG0085	RNA polymerase activity
BSY16_RS07280	COG0222	ribosome binding
BSY16_RS07285	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSY16_RS07290	COG0081	regulation of translation
BSY16_RS07295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSY16_RS07305	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSY16_RS07320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSY16_RS07335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSY16_RS07340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BSY16_RS07345	COG0583	DNA-binding transcription factor activity
BSY16_RS07365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSY16_RS07380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSY16_RS07385	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSY16_RS07390	COG1530	ribonuclease E activity
BSY16_RS07400	COG0436	Aminotransferase
BSY16_RS07410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BSY16_RS07415	COG0511	ligase activity, forming carbon-carbon bonds
BSY16_RS07420	COG0439	Biotin carboxylase
BSY16_RS07425	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BSY16_RS07445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSY16_RS07455	COG1959	2 iron, 2 sulfur cluster binding
BSY16_RS07460	COG0492	ferredoxin-NADP+ reductase activity
BSY16_RS07465	COG3811	Belongs to the UPF0386 family
BSY16_RS07475	COG0330	HflC and HflK could
BSY16_RS07490	COG0154	amidase activity
BSY16_RS07495	COG0456	acetyltransferase
BSY16_RS07500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSY16_RS07510	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BSY16_RS07515	COG2824	Alkylphosphonate utilization operon protein PhnA
BSY16_RS07520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSY16_RS07535	COG1960	acyl-CoA dehydrogenase activity
BSY16_RS07540	COG0540	Belongs to the ATCase OTCase family
BSY16_RS07545	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSY16_RS07550	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BSY16_RS07555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSY16_RS07555	COG0758	DNA mediated transformation
BSY16_RS07565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSY16_RS07570	COG0557	exoribonuclease II activity
BSY16_RS07590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSY16_RS07600	COG0784	Response regulator, receiver
BSY16_RS07610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSY16_RS07645	COG1136	(ABC) transporter
BSY16_RS07655	COG0442	prolyl-tRNA aminoacylation
BSY16_RS07665	COG0346	lactoylglutathione lyase activity
BSY16_RS07675	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BSY16_RS07675	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BSY16_RS07680	COG1007	ATP synthesis coupled electron transport
BSY16_RS07695	COG0713	ATP synthesis coupled electron transport
BSY16_RS07705	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY16_RS07710	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSY16_RS07720	COG3743	rRNA binding
BSY16_RS07720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSY16_RS07725	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BSY16_RS07735	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BSY16_RS07745	COG0649	NAD binding
BSY16_RS07750	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY16_RS07755	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY16_RS07760	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY16_RS07790	COG2188	Transcriptional regulator
BSY16_RS07800	COG1228	amidohydrolase
BSY16_RS07805	COG2986	histidine ammonia-lyase
BSY16_RS07815	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BSY16_RS07825	COG0667	Aldo Keto reductase
BSY16_RS07840	COG0583	DNA-binding transcription factor activity
BSY16_RS07865	COG0420	3'-5' exonuclease activity
BSY16_RS07880	COG0776	regulation of translation
BSY16_RS07885	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSY16_RS07890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSY16_RS07900	COG0740	serine-type endopeptidase activity
BSY16_RS07910	COG2124	cytochrome p450
BSY16_RS07925	COG1832	CoA-binding protein
BSY16_RS07930	COG1832	CoA-binding protein
BSY16_RS07955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSY16_RS07960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSY16_RS07970	COG1522	sequence-specific DNA binding
BSY16_RS07975	COG0010	Belongs to the arginase family
BSY16_RS07980	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BSY16_RS07990	COG1612	heme a metabolic process
BSY16_RS08005	COG0494	nUDIX hydrolase
BSY16_RS08025	COG0297	glycogen (starch) synthase activity
BSY16_RS08075	COG0776	regulation of translation
BSY16_RS08080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSY16_RS08085	COG0416	fatty acid biosynthetic process
BSY16_RS08105	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BSY16_RS08110	COG2814	Major facilitator Superfamily
BSY16_RS08115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSY16_RS08120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSY16_RS08130	COG2199	diguanylate cyclase activity
BSY16_RS08140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY16_RS08140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY16_RS08145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSY16_RS08150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSY16_RS08155	COG2989	Protein conserved in bacteria
BSY16_RS08170	COG0113	porphobilinogen synthase activity
BSY16_RS08180	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BSY16_RS08190	COG2336	PFAM SpoVT AbrB
BSY16_RS08200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSY16_RS08210	COG4452	Inner membrane protein CreD
BSY16_RS08220	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSY16_RS08230	COG0583	DNA-binding transcription factor activity
BSY16_RS08245	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BSY16_RS08285	COG0248	Ppx GppA phosphatase
BSY16_RS08290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BSY16_RS08300	COG0628	permease
BSY16_RS08305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSY16_RS08310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSY16_RS08315	COG0494	nUDIX hydrolase
BSY16_RS08320	COG0243	molybdopterin cofactor binding
BSY16_RS08325	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BSY16_RS08350	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS08355	COG0322	excinuclease ABC activity
BSY16_RS08360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSY16_RS08370	COG0314	molybdopterin synthase activity
BSY16_RS08395	COG0105	UTP biosynthetic process
BSY16_RS08425	COG0488	(ABC) transporter
BSY16_RS08430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSY16_RS08475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSY16_RS08490	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BSY16_RS08500	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSY16_RS08505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSY16_RS08510	COG0194	GDP metabolic process
BSY16_RS08515	COG1561	YicC-like family, N-terminal region
BSY16_RS08530	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BSY16_RS08530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSY16_RS08535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSY16_RS08540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSY16_RS08545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSY16_RS08555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSY16_RS08560	COG0667	Aldo Keto reductase
BSY16_RS08565	COG2233	PERMEase
BSY16_RS08580	COG0360	Binds together with S18 to 16S ribosomal RNA
BSY16_RS08585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSY16_RS08595	COG0359	binds to the 23S rRNA
BSY16_RS08600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSY16_RS08605	COG0305	Participates in initiation and elongation during chromosome replication
BSY16_RS08615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSY16_RS08630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSY16_RS08635	COG4221	oxidoreductase activity
BSY16_RS08665	COG1183	phosphatidylcholine synthase activity
BSY16_RS08670	COG0688	phosphatidylethanolamine metabolic process
BSY16_RS08685	COG5265	(ABC) transporter
BSY16_RS08705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY16_RS08730	COG0215	cysteine-tRNA ligase activity
BSY16_RS08745	COG1051	belongs to the nudix hydrolase family
BSY16_RS08775	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BSY16_RS08795	COG2032	superoxide dismutase activity
BSY16_RS08805	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BSY16_RS08810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BSY16_RS08815	COG2814	Major facilitator Superfamily
BSY16_RS08840	COG1418	mRNA catabolic process
BSY16_RS08855	COG1381	Involved in DNA repair and RecF pathway recombination
BSY16_RS08860	COG1388	LysM domain
BSY16_RS08860	COG1376	ErfK ybiS ycfS ynhG family protein
BSY16_RS08885	COG2183	response to ionizing radiation
BSY16_RS08890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BSY16_RS08895	COG5001	Diguanylate cyclase
BSY16_RS08905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSY16_RS08910	COG0571	ribonuclease III activity
BSY16_RS08915	COG0681	Belongs to the peptidase S26 family
BSY16_RS08920	COG0736	holo-[acyl-carrier-protein] synthase activity
BSY16_RS08940	COG1758	RNA polymerase activity
BSY16_RS08955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BSY16_RS08960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY16_RS08965	COG0741	lytic transglycosylase activity
BSY16_RS08970	COG2945	thiolester hydrolase activity
BSY16_RS08970	COG0596	Alpha beta hydrolase
BSY16_RS08975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BSY16_RS08980	COG4974	Belongs to the 'phage' integrase family
BSY16_RS08985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BSY16_RS09015	COG0625	glutathione transferase activity
BSY16_RS09025	COG0673	inositol 2-dehydrogenase activity
BSY16_RS09035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY16_RS09040	COG3962	Belongs to the TPP enzyme family
BSY16_RS09045	COG1082	Xylose isomerase domain protein TIM barrel
BSY16_RS09050	COG3718	enzyme involved in inositol metabolism
BSY16_RS09060	COG1960	acyl-CoA dehydrogenase activity
BSY16_RS09075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSY16_RS09090	COG1742	UPF0060 membrane protein
BSY16_RS09095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSY16_RS09110	COG0174	glutamine synthetase
BSY16_RS09120	COG2814	Major facilitator Superfamily
BSY16_RS09155	COG1376	ErfK ybiS ycfS ynhG family protein
BSY16_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS09175	COG0443	Heat shock 70 kDa protein
BSY16_RS09195	COG0308	aminopeptidase N
BSY16_RS09200	COG2202	Pas domain
BSY16_RS09200	COG2205	protein histidine kinase activity
BSY16_RS09210	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSY16_RS09220	COG0745	RESPONSE REGULATOR receiver
BSY16_RS09225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSY16_RS09230	COG3088	subunit of a heme lyase
BSY16_RS09235	COG1138	Cytochrome C-type biogenesis protein
BSY16_RS09240	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BSY16_RS09245	COG4235	cytochrome complex assembly
BSY16_RS09340	COG4695	Portal protein
BSY16_RS09375	COG2983	Belongs to the UPF0260 family
BSY16_RS09380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSY16_RS09425	COG2205	protein histidine kinase activity
BSY16_RS09435	COG2166	iron-sulfur cluster assembly
BSY16_RS09455	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSY16_RS09460	COG4957	zinc ion binding
BSY16_RS09465	COG1320	monovalent cation:proton antiporter activity
BSY16_RS09470	COG2212	antiporter activity
BSY16_RS09475	COG1863	multisubunit Na H antiporter MnhE subunit
BSY16_RS09480	COG0651	ATP synthesis coupled electron transport
BSY16_RS09485	COG1006	Multisubunit Na H antiporter MnhC subunit
BSY16_RS09490	COG2111	Na H antiporter
BSY16_RS09495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSY16_RS09495	COG2111	Na H antiporter
BSY16_RS09500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY16_RS09515	COG1272	protein, Hemolysin III
BSY16_RS09525	COG2514	catechol 2,3-dioxygenase activity
BSY16_RS09560	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BSY16_RS09565	COG4993	Dehydrogenase
BSY16_RS09570	COG5265	(ABC) transporter
BSY16_RS09595	COG2010	Cytochrome c
BSY16_RS09600	COG3909	cytochrome
BSY16_RS09625	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSY16_RS09630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSY16_RS09640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSY16_RS09645	COG1063	alcohol dehydrogenase
BSY16_RS09655	COG4106	trans-aconitate 2-methyltransferase activity
BSY16_RS09665	COG2814	Major facilitator Superfamily
BSY16_RS09670	COG0656	L-ascorbic acid biosynthetic process
BSY16_RS09690	COG0433	COG0433 Predicted ATPase
BSY16_RS09700	COG1764	response to oxidative stress
BSY16_RS09705	COG1846	Transcriptional regulator
BSY16_RS09715	COG2201	protein-glutamate methylesterase activity
BSY16_RS09720	COG1376	ErfK ybiS ycfS ynhG family protein
BSY16_RS09735	COG0435	Glutathione S-transferase
BSY16_RS09745	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BSY16_RS09745	COG1793	dna ligase
BSY16_RS09795	COG0583	DNA-binding transcription factor activity
BSY16_RS09835	COG3549	Plasmid maintenance system killer
BSY16_RS09880	COG0604	alcohol dehydrogenase
BSY16_RS09880	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS09880	COG3321	synthase
BSY16_RS09890	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BSY16_RS09900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSY16_RS09910	COG1309	transcriptional regulator
BSY16_RS09915	COG3119	arylsulfatase activity
BSY16_RS09920	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS09925	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BSY16_RS09940	COG0175	sulfate reduction
BSY16_RS09950	COG2895	sulfate adenylyltransferase (ATP) activity
BSY16_RS09960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY16_RS09965	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BSY16_RS09970	COG1285	pathogenesis
BSY16_RS09980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY16_RS09985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY16_RS09995	COG2223	nitrite transmembrane transporter activity
BSY16_RS10020	COG2226	methyltransferase
BSY16_RS10025	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS10040	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BSY16_RS10040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSY16_RS10085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSY16_RS10085	COG0574	Belongs to the PEP-utilizing enzyme family
BSY16_RS10095	COG1196	nuclear chromosome segregation
BSY16_RS10100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSY16_RS10110	COG1194	a g-specific adenine glycosylase
BSY16_RS10120	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BSY16_RS10150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSY16_RS10165	COG0612	Peptidase, M16
BSY16_RS10170	COG0668	transmembrane transport
BSY16_RS10180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSY16_RS10185	COG5001	Diguanylate cyclase
BSY16_RS10205	COG1678	Uncharacterized ACR, COG1678
BSY16_RS10215	COG0678	peroxiredoxin activity
BSY16_RS10215	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSY16_RS10220	COG0328	RNA-DNA hybrid ribonuclease activity
BSY16_RS10225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSY16_RS10230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSY16_RS10240	COG3346	SURF1 family
BSY16_RS10255	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BSY16_RS10260	COG0109	protoheme IX farnesyltransferase activity
BSY16_RS10265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY16_RS10270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSY16_RS10280	COG0312	modulator of DNA gyrase
BSY16_RS10285	COG0583	DNA-binding transcription factor activity
BSY16_RS10295	COG0259	pyridoxamine-phosphate oxidase activity
BSY16_RS10305	COG0484	heat shock protein binding
BSY16_RS10310	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSY16_RS10335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSY16_RS10340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSY16_RS10340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSY16_RS10360	COG3214	Protein conserved in bacteria
BSY16_RS10365	COG1122	ATPase activity
BSY16_RS10370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BSY16_RS10375	COG1268	BioY protein
BSY16_RS10380	COG0318	PFAM AMP-dependent synthetase and ligase
BSY16_RS10385	COG0183	Belongs to the thiolase family
BSY16_RS10400	COG0604	alcohol dehydrogenase
BSY16_RS10405	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSY16_RS10410	COG1722	exodeoxyribonuclease VII activity
BSY16_RS10425	COG1741	Belongs to the pirin family
BSY16_RS10455	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSY16_RS10485	COG2972	Histidine kinase
BSY16_RS10485	COG0840	transmembrane signaling receptor activity
BSY16_RS10495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSY16_RS10520	COG1960	acyl-CoA dehydrogenase activity
BSY16_RS10535	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BSY16_RS10540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSY16_RS10560	COG0009	L-threonylcarbamoyladenylate synthase
BSY16_RS10580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSY16_RS10600	COG0151	Belongs to the GarS family
BSY16_RS10610	COG1683	Conserved Protein
BSY16_RS10615	COG0751	glycine-tRNA ligase activity
BSY16_RS10635	COG1704	LemA family
BSY16_RS10650	COG0752	glycyl-tRNA synthetase alpha subunit
BSY16_RS10655	COG1088	dTDP-glucose 4,6-dehydratase activity
BSY16_RS10680	COG0142	geranyltranstransferase activity
BSY16_RS10690	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSY16_RS10695	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSY16_RS10715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSY16_RS10720	COG2378	regulation of single-species biofilm formation
BSY16_RS10730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSY16_RS10735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSY16_RS10740	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSY16_RS10745	COG0356	it plays a direct role in the translocation of protons across the membrane
BSY16_RS10760	COG3158	transport of potassium into the cell
BSY16_RS10770	COG0489	protein tyrosine kinase activity
BSY16_RS10775	COG2771	luxR family
BSY16_RS10780	COG2771	luxR family
BSY16_RS10785	COG1414	Transcriptional regulator
BSY16_RS10790	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS10795	COG3734	2-keto-3-deoxy-galactonokinase
BSY16_RS10800	COG0800	Aldolase
BSY16_RS10805	COG3386	PFAM SMP-30 Gluconolaconase
BSY16_RS10815	COG5598	trimethylamine methyltransferase
BSY16_RS10820	COG0583	DNA-binding transcription factor activity
BSY16_RS10830	COG5001	Diguanylate cyclase
BSY16_RS10830	COG3300	MHYT domain
BSY16_RS10835	COG0784	Response regulator, receiver
BSY16_RS10840	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSY16_RS10850	COG1663	tetraacyldisaccharide 4'-kinase activity
BSY16_RS10855	COG0546	phosphoglycolate phosphatase activity
BSY16_RS10860	COG1519	Transferase
BSY16_RS10870	COG0483	inositol monophosphate 1-phosphatase activity
BSY16_RS10875	COG0312	modulator of DNA gyrase
BSY16_RS10880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSY16_RS10880	COG0475	glutathione-regulated potassium exporter activity
BSY16_RS10890	COG0742	ribosomal rna small subunit methyltransferase
BSY16_RS10895	COG1187	pseudouridine synthase activity
BSY16_RS10900	COG0590	tRNA wobble adenosine to inosine editing
BSY16_RS10915	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSY16_RS10920	COG0196	riboflavin kinase activity
BSY16_RS10930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSY16_RS10935	COG0459	protein refolding
BSY16_RS10945	COG5001	Diguanylate cyclase
BSY16_RS10945	COG3300	MHYT domain
BSY16_RS10955	COG0625	glutathione transferase activity
BSY16_RS10960	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSY16_RS10965	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BSY16_RS10970	COG0124	histidyl-tRNA synthetase
BSY16_RS11000	COG0519	Catalyzes the synthesis of GMP from XMP
BSY16_RS11005	COG1376	ErfK ybiS ycfS ynhG family protein
BSY16_RS11020	COG0247	lactate metabolic process
BSY16_RS11025	COG0277	FAD linked oxidase domain protein
BSY16_RS11030	COG0277	FAD linked oxidase domain protein
BSY16_RS11035	COG0583	DNA-binding transcription factor activity
BSY16_RS11050	COG2186	Transcriptional regulator
BSY16_RS11060	COG0306	phosphate transporter
BSY16_RS11085	COG0840	transmembrane signaling receptor activity
BSY16_RS11095	COG0583	DNA-binding transcription factor activity
BSY16_RS11110	COG0412	Dienelactone hydrolase
BSY16_RS11135	COG0477	Major facilitator Superfamily
BSY16_RS11145	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BSY16_RS11150	COG0248	Ppx GppA phosphatase
BSY16_RS11180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSY16_RS11185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSY16_RS11215	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BSY16_RS11225	COG0732	type I restriction modification DNA specificity domain
BSY16_RS11230	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BSY16_RS11245	COG1401	restriction endodeoxyribonuclease activity
BSY16_RS11420	COG0305	Participates in initiation and elongation during chromosome replication
BSY16_RS11535	COG3422	double-strand break repair
BSY16_RS11545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSY16_RS11555	COG0346	lactoylglutathione lyase activity
BSY16_RS11560	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BSY16_RS11565	COG4149	molybdate abc transporter
BSY16_RS11570	COG0725	ABC transporter, periplasmic molybdate-binding protein
BSY16_RS11585	COG0745	RESPONSE REGULATOR receiver
BSY16_RS11590	COG2198	Histidine kinase
BSY16_RS11590	COG0643	Histidine kinase
BSY16_RS11595	COG0835	chemotaxis
BSY16_RS11605	COG0840	transmembrane signaling receptor activity
BSY16_RS11610	COG0835	chemotaxis
BSY16_RS11620	COG2201	protein-glutamate methylesterase activity
BSY16_RS11625	COG1192	Involved in chromosome partitioning
BSY16_RS11680	COG0625	glutathione transferase activity
BSY16_RS11695	COG1388	LysM domain
BSY16_RS11695	COG1376	ErfK ybiS ycfS ynhG family protein
BSY16_RS11700	COG3034	peptidoglycan biosynthetic process
BSY16_RS11710	COG0789	Transcriptional regulator
BSY16_RS11715	COG1999	signal sequence binding
BSY16_RS11730	COG0019	diaminopimelate decarboxylase activity
BSY16_RS11740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY16_RS11745	COG2368	4-hydroxyphenylacetate
BSY16_RS11760	COG0789	Transcriptional regulator
BSY16_RS11790	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSY16_RS11805	COG0583	DNA-binding transcription factor activity
BSY16_RS11810	COG0402	S-adenosylhomocysteine deaminase activity
BSY16_RS11865	COG0583	DNA-binding transcription factor activity
BSY16_RS11870	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS11880	COG3842	ATPase activity
BSY16_RS11885	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY16_RS11890	COG1177	transmembrane transport
BSY16_RS11910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSY16_RS11920	COG1879	ABC-type sugar transport system periplasmic component
BSY16_RS11925	COG1129	ABC transporter
BSY16_RS11930	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS11935	COG2376	Dihydroxyacetone kinase
BSY16_RS11945	COG1522	sequence-specific DNA binding
BSY16_RS11955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY16_RS11960	COG0402	S-adenosylhomocysteine deaminase activity
BSY16_RS11965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY16_RS11970	COG1802	Transcriptional regulator
BSY16_RS12005	COG2862	Uncharacterized protein family, UPF0114
BSY16_RS12015	COG3237	CsbD-like
BSY16_RS12040	COG0784	Response regulator, receiver
BSY16_RS12045	COG0251	oxidation-reduction process
BSY16_RS12050	COG3265	gluconokinase activity
BSY16_RS12055	COG4608	Belongs to the ABC transporter superfamily
BSY16_RS12060	COG0444	Belongs to the ABC transporter superfamily
BSY16_RS12065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY16_RS12070	COG0601	transmembrane transport
BSY16_RS12075	COG0747	negative chemotaxis
BSY16_RS12090	COG1959	2 iron, 2 sulfur cluster binding
BSY16_RS12095	COG1840	ABC-type Fe3 transport system, periplasmic component
BSY16_RS12105	COG4269	membrane
BSY16_RS12135	COG1215	transferase activity, transferring glycosyl groups
BSY16_RS12160	COG2205	protein histidine kinase activity
BSY16_RS12165	COG1178	ABC-type Fe3 transport system permease component
BSY16_RS12170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY16_RS12180	COG1177	transmembrane transport
BSY16_RS12185	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY16_RS12190	COG3842	ATPase activity
BSY16_RS12205	COG2224	Isocitrate lyase
BSY16_RS12240	COG0840	transmembrane signaling receptor activity
BSY16_RS12240	COG2972	Histidine kinase
BSY16_RS12250	COG2081	HI0933 family
BSY16_RS12260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS12265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BSY16_RS12270	COG0363	glucosamine-6-phosphate deaminase activity
BSY16_RS12275	COG0129	dihydroxy-acid dehydratase activity
BSY16_RS12285	COG3842	ATPase activity
BSY16_RS12290	COG0366	Alpha amylase catalytic
BSY16_RS12295	COG0395	ABC-type sugar transport system, permease component
BSY16_RS12300	COG1175	transmembrane transport
BSY16_RS12305	COG1653	transport
BSY16_RS12310	COG1609	Transcriptional regulator
BSY16_RS12315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSY16_RS12345	COG1684	flagellar biosynthetic protein fliR
BSY16_RS12350	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSY16_RS12355	COG4794	Type iii secretion
BSY16_RS12360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BSY16_RS12365	COG5443	negative regulation of bacterial-type flagellum assembly
BSY16_RS12385	COG1749	Flagellar hook protein flgE
BSY16_RS12420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSY16_RS12450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSY16_RS12455	COG1338	Plays a role in the flagellum-specific transport system
BSY16_RS12465	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BSY16_RS12475	COG1706	bacterial-type flagellum-dependent cell motility
BSY16_RS12480	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BSY16_RS12485	COG4786	Flagellar basal body rod
BSY16_RS12490	COG1677	Flagellar hook-basal body complex protein FliE
BSY16_RS12495	COG1558	bacterial-type flagellum-dependent cell motility
BSY16_RS12500	COG1815	bacterial-type flagellum-dependent cell motility
BSY16_RS12510	COG1157	protein secretion by the type III secretion system
BSY16_RS12515	COG4786	Flagellar basal body rod
BSY16_RS12525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSY16_RS12530	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSY16_RS12535	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSY16_RS12540	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSY16_RS12545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSY16_RS12560	COG2771	luxR family
BSY16_RS12565	COG1766	The M ring may be actively involved in energy transduction
BSY16_RS12575	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BSY16_RS12580	COG0745	RESPONSE REGULATOR receiver
BSY16_RS12585	COG2201	protein-glutamate methylesterase activity
BSY16_RS12590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSY16_RS12595	COG0835	chemotaxis
BSY16_RS12600	COG2198	Histidine kinase
BSY16_RS12600	COG0643	Histidine kinase
BSY16_RS12605	COG0745	RESPONSE REGULATOR receiver
BSY16_RS12615	COG0840	transmembrane signaling receptor activity
BSY16_RS12625	COG3254	rhamnose metabolic process
BSY16_RS12635	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS12640	COG1129	ABC transporter
BSY16_RS12650	COG1349	DNA-binding transcription factor activity
BSY16_RS12655	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS12655	COG3347	Dehydrogenase
BSY16_RS12660	COG4952	isomerase
BSY16_RS12685	COG3739	integral membrane protein
BSY16_RS12710	COG0539	negative regulation of cytoplasmic translation
BSY16_RS12715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BSY16_RS12750	COG1162	GTPase activity
BSY16_RS12760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSY16_RS12765	COG0459	protein refolding
BSY16_RS12800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSY16_RS12810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSY16_RS12835	COG1185	polyribonucleotide nucleotidyltransferase activity
BSY16_RS12840	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSY16_RS12855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSY16_RS12860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSY16_RS12865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSY16_RS12880	COG0779	Required for maturation of 30S ribosomal subunits
BSY16_RS12885	COG2814	Major facilitator Superfamily
BSY16_RS12890	COG2951	lytic endotransglycosylase activity
BSY16_RS12895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSY16_RS12910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSY16_RS12915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BSY16_RS12930	COG2816	NAD+ diphosphatase activity
BSY16_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS12940	COG1309	transcriptional regulator
BSY16_RS12945	COG1605	Chorismate mutase
BSY16_RS12945	COG0077	Prephenate dehydratase
BSY16_RS12950	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BSY16_RS12955	COG3474	cytochrome
BSY16_RS12965	COG2373	Large extracellular alpha-helical protein
BSY16_RS12970	COG4953	penicillin-binding protein 1C
BSY16_RS12975	COG1024	Enoyl-CoA hydratase
BSY16_RS12995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY16_RS13000	COG1960	acyl-CoA dehydrogenase activity
BSY16_RS13010	COG1522	sequence-specific DNA binding
BSY16_RS13070	COG2089	acid synthase
BSY16_RS13085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSY16_RS13095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSY16_RS13100	COG5328	Belongs to the UPF0262 family
BSY16_RS13105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSY16_RS13110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSY16_RS13115	COG0424	maF-like protein
BSY16_RS13120	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BSY16_RS13130	COG0436	Aminotransferase
BSY16_RS13150	COG1294	oxidase, subunit
BSY16_RS13155	COG1271	oxidase subunit
BSY16_RS13165	COG1473	amidohydrolase
BSY16_RS13175	COG4215	(ABC) transporter
BSY16_RS13180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY16_RS13215	COG1970	mechanosensitive ion channel activity
BSY16_RS13220	COG2205	protein histidine kinase activity
BSY16_RS13220	COG0784	Response regulator, receiver
BSY16_RS13220	COG2198	Histidine kinase
BSY16_RS13240	COG0167	dihydroorotate dehydrogenase activity
BSY16_RS13250	COG0534	Mate efflux family protein
BSY16_RS13280	COG1201	RNA secondary structure unwinding
BSY16_RS13290	COG2133	pyrroloquinoline quinone binding
BSY16_RS13315	COG0730	response to heat
BSY16_RS13325	COG1960	acyl-CoA dehydrogenase activity
BSY16_RS13330	COG0183	Belongs to the thiolase family
BSY16_RS13345	COG1024	Enoyl-CoA hydratase
BSY16_RS13345	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY16_RS13350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSY16_RS13365	COG0784	Response regulator, receiver
BSY16_RS13370	COG2205	protein histidine kinase activity
BSY16_RS13375	COG0697	spore germination
BSY16_RS13390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY16_RS13410	COG0717	Belongs to the dCTP deaminase family
BSY16_RS13420	COG2967	ApaG domain
BSY16_RS13430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSY16_RS13435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSY16_RS13445	COG0745	RESPONSE REGULATOR receiver
BSY16_RS13450	COG0704	Plays a role in the regulation of phosphate uptake
BSY16_RS13455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSY16_RS13465	COG0573	inorganic phosphate transmembrane transporter activity
BSY16_RS13475	COG5002	protein histidine kinase activity
BSY16_RS13480	COG2326	polyphosphate kinase activity
BSY16_RS13520	COG0628	permease
BSY16_RS13525	COG0318	PFAM AMP-dependent synthetase and ligase
BSY16_RS13530	COG0166	Belongs to the GPI family
BSY16_RS13535	COG0438	transferase activity, transferring glycosyl groups
BSY16_RS13545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSY16_RS13550	COG2259	Doxx family
BSY16_RS13565	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BSY16_RS13580	COG3938	Belongs to the proline racemase family
BSY16_RS13610	COG2205	protein histidine kinase activity
BSY16_RS13615	COG0840	transmembrane signaling receptor activity
BSY16_RS13615	COG2972	Histidine kinase
BSY16_RS13620	COG0594	ribonuclease P activity
BSY16_RS13625	COG0706	membrane insertase activity
BSY16_RS13635	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BSY16_RS13640	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSY16_RS13655	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSY16_RS13680	COG2171	N-acyltransferase activity
BSY16_RS13690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSY16_RS13700	COG0101	tRNA pseudouridine synthase activity
BSY16_RS13705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSY16_RS13710	COG0242	peptide deformylase activity
BSY16_RS13720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY16_RS13725	COG0840	transmembrane signaling receptor activity
BSY16_RS13740	COG0071	Belongs to the small heat shock protein (HSP20) family
BSY16_RS13750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSY16_RS13755	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSY16_RS13760	COG1396	sequence-specific DNA binding
BSY16_RS13765	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BSY16_RS13775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSY16_RS13780	COG1702	phosphate starvation-inducible protein PhoH
BSY16_RS13785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSY16_RS13805	COG1214	PFAM Peptidase M22, glycoprotease
BSY16_RS13810	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSY16_RS13820	COG0180	Tryptophanyl-tRNA synthetase
BSY16_RS13835	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BSY16_RS13840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BSY16_RS13845	COG0280	phosphate acetyltransferase
BSY16_RS13845	COG0281	malic enzyme
BSY16_RS13860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSY16_RS13865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSY16_RS13870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BSY16_RS13870	COG0116	Belongs to the methyltransferase superfamily
BSY16_RS13885	COG0776	regulation of translation
BSY16_RS13900	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BSY16_RS13905	COG1137	ATPase activity
BSY16_RS13910	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BSY16_RS13915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSY16_RS13920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSY16_RS13925	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSY16_RS13930	COG1420	regulation of RNA biosynthetic process
BSY16_RS13935	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BSY16_RS13945	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSY16_RS13950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSY16_RS13960	COG0583	DNA-binding transcription factor activity
BSY16_RS13970	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSY16_RS13975	COG0268	Binds directly to 16S ribosomal RNA
BSY16_RS13980	COG1024	Enoyl-CoA hydratase
BSY16_RS13985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSY16_RS13990	COG2226	methyltransferase
BSY16_RS13995	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSY16_RS14005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSY16_RS14030	COG0351	phosphomethylpyrimidine kinase
BSY16_RS14035	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BSY16_RS14040	COG0756	dUTP diphosphatase activity
BSY16_RS14050	COG1280	lysine exporter protein (LysE YggA)
BSY16_RS14075	COG0189	ligase activity
BSY16_RS14090	COG3842	ATPase activity
BSY16_RS14095	COG0395	ABC-type sugar transport system, permease component
BSY16_RS14100	COG1175	transmembrane transport
BSY16_RS14110	COG0792	nuclease activity
BSY16_RS14115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSY16_RS14125	COG3963	phosphatidate phosphatase activity
BSY16_RS14135	COG0284	orotidine-5'-phosphate decarboxylase activity
BSY16_RS14150	COG1968	undecaprenyl-diphosphatase activity
BSY16_RS14160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSY16_RS14170	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BSY16_RS14200	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BSY16_RS14215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSY16_RS14215	COG0519	Catalyzes the synthesis of GMP from XMP
BSY16_RS14225	COG1595	DNA-templated transcription, initiation
BSY16_RS14230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSY16_RS14240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSY16_RS14250	COG1522	sequence-specific DNA binding
BSY16_RS14255	COG1448	Aminotransferase
BSY16_RS14265	COG1393	Belongs to the ArsC family
BSY16_RS14305	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS14320	COG0488	(ABC) transporter
BSY16_RS14335	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSY16_RS14340	COG0411	ABC transporter
BSY16_RS14355	COG0683	leucine binding
BSY16_RS14365	COG3485	protocatechuate 3,4-dioxygenase
BSY16_RS14370	COG3485	protocatechuate 3,4-dioxygenase
BSY16_RS14375	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSY16_RS14380	COG2267	carboxylic ester hydrolase activity
BSY16_RS14385	COG0583	DNA-binding transcription factor activity
BSY16_RS14410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSY16_RS14415	COG1414	Transcriptional regulator
BSY16_RS14425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSY16_RS14430	COG0183	Belongs to the thiolase family
BSY16_RS14435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSY16_RS14440	COG2309	aminopeptidase activity
BSY16_RS14450	COG0697	spore germination
BSY16_RS14455	COG1846	Transcriptional regulator
BSY16_RS14460	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSY16_RS14465	COG1570	exodeoxyribonuclease VII activity
BSY16_RS14500	COG5006	permease, DMT superfamily
BSY16_RS14505	COG2885	chlorophyll binding
BSY16_RS14530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSY16_RS14530	COG0072	phenylalanine-tRNA ligase activity
BSY16_RS14535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSY16_RS14540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSY16_RS14545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSY16_RS14550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSY16_RS14565	COG0667	Aldo Keto reductase
BSY16_RS14605	COG0481	GTPase activity
BSY16_RS14625	COG0356	it plays a direct role in the translocation of protons across the membrane
BSY16_RS14630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSY16_RS14650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSY16_RS14680	COG1072	(Pantothenic acid kinase))
BSY16_RS14685	COG0418	dihydroorotase activity
BSY16_RS14690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY16_RS14720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSY16_RS14730	COG0517	IMP dehydrogenase activity
BSY16_RS14740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY16_RS14750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSY16_RS14755	COG2807	transmembrane transport
BSY16_RS14765	COG3938	Belongs to the proline racemase family
BSY16_RS14780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY16_RS14790	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BSY16_RS14820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS14830	COG1942	4-Oxalocrotonate Tautomerase
BSY16_RS14860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY16_RS14865	COG1744	ABC transporter substrate-binding protein PnrA-like
BSY16_RS14870	COG2900	Belongs to the SlyX family
BSY16_RS14875	COG3845	ABC transporter
BSY16_RS14880	COG4603	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS14885	COG1079	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS14895	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BSY16_RS14900	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BSY16_RS14905	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BSY16_RS14915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BSY16_RS14920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BSY16_RS14925	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BSY16_RS14960	COG4964	Belongs to the GSP D family
BSY16_RS14995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSY16_RS15005	COG0791	NLP P60 protein
BSY16_RS15015	COG4172	Belongs to the ABC transporter superfamily
BSY16_RS15020	COG4239	(ABC) transporter, permease
BSY16_RS15025	COG4174	ABC transporter (Permease)
BSY16_RS15030	COG4166	transmembrane transport
BSY16_RS15035	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BSY16_RS15040	COG1803	Methylglyoxal synthase
BSY16_RS15045	COG0837	glucose binding
BSY16_RS15050	COG1132	(ABC) transporter
BSY16_RS15055	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSY16_RS15060	COG0588	phosphoglycerate mutase activity
BSY16_RS15065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSY16_RS15070	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSY16_RS15075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSY16_RS15095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY16_RS15100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSY16_RS15105	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BSY16_RS15110	COG1509	lysine 2,3-aminomutase activity
BSY16_RS15115	COG0840	transmembrane signaling receptor activity
BSY16_RS15145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSY16_RS15160	COG0484	heat shock protein binding
BSY16_RS15165	COG0443	Heat shock 70 kDa protein
BSY16_RS15170	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSY16_RS15200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSY16_RS15200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSY16_RS15205	COG0450	alkyl hydroperoxide reductase
BSY16_RS15245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSY16_RS15255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSY16_RS15270	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BSY16_RS15280	COG1132	(ABC) transporter
BSY16_RS15290	COG2084	Dehydrogenase
BSY16_RS15295	COG3622	Belongs to the hyi family
BSY16_RS15300	COG3960	tartronate-semialdehyde synthase activity
BSY16_RS15305	COG1414	Transcriptional regulator
BSY16_RS15315	COG0402	S-adenosylhomocysteine deaminase activity
BSY16_RS15335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSY16_RS15340	COG2080	2 iron, 2 sulfur cluster binding
BSY16_RS15345	COG2351	hydroxyisourate hydrolase activity
BSY16_RS15355	COG4266	Belongs to the allantoicase family
BSY16_RS15360	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BSY16_RS15375	COG2252	PERMEase
BSY16_RS15380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSY16_RS15425	COG1643	Atp-dependent helicase
BSY16_RS15435	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BSY16_RS15455	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BSY16_RS15470	COG2124	cytochrome p450
BSY16_RS15480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BSY16_RS15490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BSY16_RS15495	COG0131	Imidazoleglycerol-phosphate dehydratase
BSY16_RS15505	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSY16_RS15510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSY16_RS15515	COG0107	imidazoleglycerol-phosphate synthase activity
BSY16_RS15520	COG0140	phosphoribosyl-ATP diphosphatase activity
BSY16_RS15525	COG1072	(Pantothenic acid kinase))
BSY16_RS15535	COG1652	LysM domain
BSY16_RS15545	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BSY16_RS15550	COG0745	RESPONSE REGULATOR receiver
BSY16_RS15555	COG2205	protein histidine kinase activity
BSY16_RS15570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSY16_RS15575	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSY16_RS15580	COG2205	protein histidine kinase activity
BSY16_RS15585	COG3178	'Phosphotransferase
BSY16_RS15590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSY16_RS15615	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSY16_RS15620	COG0159	tryptophan synthase activity
BSY16_RS15625	COG0133	tryptophan synthase activity
BSY16_RS15630	COG0135	phosphoribosylanthranilate isomerase activity
BSY16_RS15660	COG1063	alcohol dehydrogenase
BSY16_RS15665	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS15690	COG1802	Transcriptional regulator
BSY16_RS15695	COG0246	Mannitol dehydrogenase
BSY16_RS15745	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BSY16_RS15750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSY16_RS15755	COG0237	dephospho-CoA kinase activity
BSY16_RS15760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSY16_RS15765	COG0424	maF-like protein
BSY16_RS15770	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BSY16_RS15775	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSY16_RS15780	COG1981	membrane
BSY16_RS15785	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSY16_RS15790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSY16_RS15795	COG0445	tRNA wobble uridine modification
BSY16_RS15800	COG0357	Ribosomal RNA small subunit methyltransferase G
BSY16_RS15825	COG0495	leucyl-tRNA aminoacylation
BSY16_RS15845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY16_RS15855	COG0501	Belongs to the peptidase M48B family
BSY16_RS15860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSY16_RS15860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSY16_RS15870	COG0138	bifunctional purine biosynthesis protein purh
BSY16_RS15875	COG2270	Major facilitator Superfamily
BSY16_RS15885	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BSY16_RS15890	COG0288	reversible hydration of carbon dioxide
BSY16_RS15900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSY16_RS15910	COG0671	phosphoesterase, PA-phosphatase related
BSY16_RS15915	COG0473	3-isopropylmalate dehydrogenase activity
BSY16_RS15925	COG0066	3-isopropylmalate dehydratase activity
BSY16_RS15965	COG0494	nUDIX hydrolase
BSY16_RS15975	COG0793	Belongs to the peptidase S41A family
BSY16_RS15985	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BSY16_RS15990	COG0799	negative regulation of ribosome biogenesis
BSY16_RS15995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSY16_RS16000	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSY16_RS16005	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSY16_RS16010	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSY16_RS16030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSY16_RS16035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSY16_RS16050	COG0488	(ABC) transporter
BSY16_RS16075	COG1879	ABC-type sugar transport system periplasmic component
BSY16_RS16080	COG1129	ABC transporter
BSY16_RS16085	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS16090	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS16105	COG0251	oxidation-reduction process
BSY16_RS16135	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSY16_RS16145	COG4120	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS16150	COG0410	ABC transporter
BSY16_RS16155	COG3738	Protein conserved in bacteria
BSY16_RS16165	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS16170	COG0137	argininosuccinate synthase activity
BSY16_RS16175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS16180	COG0174	glutamine synthetase
BSY16_RS16195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS16210	COG0436	Aminotransferase
BSY16_RS16215	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS16225	COG5383	Protein conserved in bacteria
BSY16_RS16235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS16240	COG2223	nitrite transmembrane transporter activity
BSY16_RS16290	COG0583	DNA-binding transcription factor activity
BSY16_RS16295	COG2855	membrane
BSY16_RS16310	COG3459	Glycosyltransferase 36 associated
BSY16_RS16320	COG1132	(ABC) transporter
BSY16_RS16330	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BSY16_RS16350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSY16_RS16355	COG4133	protoheme IX ABC transporter activity
BSY16_RS16360	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSY16_RS16365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSY16_RS16380	COG2917	probably involved in intracellular septation
BSY16_RS16385	COG0552	protein localization to endoplasmic reticulum
BSY16_RS16390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSY16_RS16395	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSY16_RS16410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSY16_RS16415	COG0287	Prephenate dehydrogenase
BSY16_RS16415	COG1605	Chorismate mutase
BSY16_RS16420	COG0228	four-way junction DNA binding
BSY16_RS16425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSY16_RS16430	COG0336	Belongs to the RNA methyltransferase TrmD family
BSY16_RS16440	COG0335	large ribosomal subunit rRNA binding
BSY16_RS16455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY16_RS16460	COG0765	amino acid transport
BSY16_RS16470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSY16_RS16480	COG0656	L-ascorbic acid biosynthetic process
BSY16_RS16490	COG0745	RESPONSE REGULATOR receiver
BSY16_RS16505	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BSY16_RS16510	COG1674	ftsk spoiiie
BSY16_RS16515	COG0004	ammonium transporteR
BSY16_RS16520	COG0347	Belongs to the P(II) protein family
BSY16_RS16525	COG1946	Acyl-CoA thioesterase
BSY16_RS16530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY16_RS16535	COG2835	tetraacyldisaccharide 4'-kinase activity
BSY16_RS16595	COG2207	Transcriptional regulator
BSY16_RS16605	COG0840	transmembrane signaling receptor activity
BSY16_RS16620	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BSY16_RS16630	COG0488	(ABC) transporter
BSY16_RS16650	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BSY16_RS16660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY16_RS16665	COG1329	Transcriptional regulator
BSY16_RS16670	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BSY16_RS16705	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BSY16_RS16715	COG4181	ATPase activity
BSY16_RS16725	COG0670	Belongs to the BI1 family
BSY16_RS16730	COG1349	DNA-binding transcription factor activity
BSY16_RS16735	COG2223	nitrite transmembrane transporter activity
BSY16_RS16740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSY16_RS16750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSY16_RS16755	COG0142	geranyltranstransferase activity
BSY16_RS16760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSY16_RS16770	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSY16_RS16780	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BSY16_RS16795	COG2154	pterin-4-alpha-carbinolamine dehydratase
BSY16_RS16810	COG2814	Major facilitator Superfamily
BSY16_RS16860	COG0339	signal peptide processing
BSY16_RS16870	COG1217	gtp-binding protein TYPA
BSY16_RS16885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BSY16_RS16895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSY16_RS16920	COG0181	hydroxymethylbilane synthase activity
BSY16_RS16925	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSY16_RS16930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSY16_RS16955	COG2009	succinate dehydrogenase
BSY16_RS16980	COG3541	Predicted nucleotidyltransferase
BSY16_RS16985	COG2845	Protein of unknown function (DUF459)
BSY16_RS16990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BSY16_RS16995	COG0039	L-malate dehydrogenase activity
BSY16_RS17000	COG0045	succinate-CoA ligase (ADP-forming) activity
BSY16_RS17005	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSY16_RS17015	COG0567	Dehydrogenase, E1 component
BSY16_RS17020	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY16_RS17040	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS17060	COG4974	Belongs to the 'phage' integrase family
BSY16_RS17065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSY16_RS17080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSY16_RS17085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSY16_RS17090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSY16_RS17095	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSY16_RS17100	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSY16_RS17105	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BSY16_RS17105	COG0662	Cupin 2, conserved barrel domain protein
BSY16_RS17135	COG1454	alcohol dehydrogenase
BSY16_RS17140	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS17145	COG4948	Mandelate Racemase Muconate Lactonizing
BSY16_RS17150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSY16_RS17165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSY16_RS17180	COG2226	methyltransferase
BSY16_RS17195	COG0494	nUDIX hydrolase
BSY16_RS17200	COG0456	acetyltransferase
BSY16_RS17200	COG0454	-acetyltransferase
BSY16_RS17205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSY16_RS17210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSY16_RS17215	COG0653	protein targeting
BSY16_RS17230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY16_RS17265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY16_RS17275	COG0300	oxidoreductase activity
BSY16_RS17285	COG2096	Adenosyltransferase
BSY16_RS17295	COG2086	electron transfer activity
BSY16_RS17300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BSY16_RS17305	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY16_RS17310	COG4150	thiosulfate binding
BSY16_RS17320	COG4208	sulfate ABC transporter
BSY16_RS17325	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSY16_RS17330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSY16_RS17335	COG0165	Argininosuccinate lyase
BSY16_RS17360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BSY16_RS17370	COG2884	Cell division ATP-binding protein ftsE
BSY16_RS17390	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BSY16_RS17400	COG0287	Prephenate dehydrogenase
BSY16_RS17405	COG2226	methyltransferase
BSY16_RS17410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY16_RS17430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSY16_RS17435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BSY16_RS17465	COG4536	flavin adenine dinucleotide binding
BSY16_RS17470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSY16_RS17475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSY16_RS17480	COG4974	Belongs to the 'phage' integrase family
BSY16_RS17485	COG0825	malonyl-CoA metabolic process
BSY16_RS17490	COG3034	peptidoglycan biosynthetic process
BSY16_RS17500	COG0523	cobalamin synthesis protein
BSY16_RS17505	COG1686	Belongs to the peptidase S11 family
BSY16_RS17510	COG1473	amidohydrolase
BSY16_RS17540	COG0395	ABC-type sugar transport system, permease component
BSY16_RS17545	COG1063	alcohol dehydrogenase
BSY16_RS17550	COG3842	ATPase activity
BSY16_RS17555	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BSY16_RS17575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSY16_RS17580	COG0156	8-amino-7-oxononanoate synthase activity
BSY16_RS17605	COG0729	surface antigen
BSY16_RS17620	COG0010	Belongs to the arginase family
BSY16_RS17625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSY16_RS17630	COG0835	chemotaxis
BSY16_RS17645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSY16_RS17650	COG3383	formate dehydrogenase (NAD+) activity
BSY16_RS17675	COG0604	alcohol dehydrogenase
BSY16_RS17680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BSY16_RS17690	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BSY16_RS17695	COG2894	cell division
BSY16_RS17705	COG0300	oxidoreductase activity
BSY16_RS17720	COG3842	ATPase activity
BSY16_RS17725	COG3842	ATPase activity
BSY16_RS17735	COG0395	ABC-type sugar transport system, permease component
BSY16_RS17755	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS17760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSY16_RS17765	COG0527	aspartate kinase activity
BSY16_RS17770	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BSY16_RS17775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSY16_RS17780	COG2890	protein-(glutamine-N5) methyltransferase activity
BSY16_RS17790	COG0542	response to heat
BSY16_RS17795	COG0739	heme binding
BSY16_RS17860	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS17870	COG3842	ATPase activity
BSY16_RS17885	COG0698	ribose 5-phosphate isomerase
BSY16_RS17890	COG0149	triose-phosphate isomerase activity
BSY16_RS17895	COG1349	DNA-binding transcription factor activity
BSY16_RS17925	COG1129	ABC transporter
BSY16_RS17930	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS17935	COG1879	ABC-type sugar transport system periplasmic component
BSY16_RS17940	COG1349	DNA-binding transcription factor activity
BSY16_RS17945	COG1070	Carbohydrate kinase
BSY16_RS17950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BSY16_RS17955	COG0287	Prephenate dehydrogenase
BSY16_RS17970	COG1129	ABC transporter
BSY16_RS17975	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS17980	COG0673	inositol 2-dehydrogenase activity
BSY16_RS18020	COG2205	protein histidine kinase activity
BSY16_RS18025	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS18030	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS18035	COG1129	ABC transporter
BSY16_RS18040	COG1879	ABC-type sugar transport system periplasmic component
BSY16_RS18045	COG1609	Transcriptional regulator
BSY16_RS18065	COG4214	carbohydrate transport
BSY16_RS18075	COG1069	ribulokinase activity
BSY16_RS18090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BSY16_RS18115	COG0517	IMP dehydrogenase activity
BSY16_RS18125	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS18130	COG0318	PFAM AMP-dependent synthetase and ligase
BSY16_RS18135	COG0583	DNA-binding transcription factor activity
BSY16_RS18145	COG3257	ureidoglycine aminohydrolase activity
BSY16_RS18170	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BSY16_RS18180	COG1846	Transcriptional regulator
BSY16_RS18195	COG5441	Belongs to the UPF0261 family
BSY16_RS18205	COG0531	amino acid
BSY16_RS18210	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS18220	COG3971	2-oxopent-4-enoate hydratase activity
BSY16_RS18225	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSY16_RS18250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY16_RS18270	COG1695	Transcriptional regulator
BSY16_RS18280	COG3585	molybdate ion transport
BSY16_RS18315	COG0670	Belongs to the BI1 family
BSY16_RS18330	COG1238	metal cluster binding
BSY16_RS18360	COG1396	sequence-specific DNA binding
BSY16_RS18365	COG1126	abc transporter atp-binding protein
BSY16_RS18370	COG0765	amino acid transport
BSY16_RS18375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY16_RS18380	COG4166	transmembrane transport
BSY16_RS18385	COG0601	transmembrane transport
BSY16_RS18390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY16_RS18395	COG4172	Belongs to the ABC transporter superfamily
BSY16_RS18405	COG5001	Diguanylate cyclase
BSY16_RS18415	COG0183	Belongs to the thiolase family
BSY16_RS18420	COG3396	Phenylacetate-CoA oxygenase
BSY16_RS18425	COG3460	Phenylacetate-CoA oxygenase
BSY16_RS18430	COG3396	Phenylacetate-CoA oxygenase
BSY16_RS18435	COG2151	metal-sulfur cluster biosynthetic enzyme
BSY16_RS18440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSY16_RS18450	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS18450	COG2030	dehydratase
BSY16_RS18455	COG1607	acyl-coa hydrolase
BSY16_RS18460	COG1309	transcriptional regulator
BSY16_RS18470	COG2050	protein possibly involved in aromatic compounds catabolism
BSY16_RS18475	COG1024	Enoyl-CoA hydratase
BSY16_RS18480	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS18485	COG0683	leucine binding
BSY16_RS18510	COG1024	Enoyl-CoA hydratase
BSY16_RS18510	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY16_RS18520	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS18530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY16_RS18540	COG1732	Glycine betaine
BSY16_RS18545	COG1174	glycine betaine transport
BSY16_RS18550	COG1125	glycine betaine transport
BSY16_RS18555	COG1174	glycine betaine transport
BSY16_RS18575	COG1028	Short-chain dehydrogenase reductase Sdr
BSY16_RS18585	COG3842	ATPase activity
BSY16_RS18590	COG0395	ABC-type sugar transport system, permease component
BSY16_RS18595	COG1175	transmembrane transport
BSY16_RS18600	COG1653	transport
BSY16_RS18605	COG1609	Transcriptional regulator
BSY16_RS18610	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS18615	COG1024	Enoyl-CoA hydratase
BSY16_RS18625	COG0673	inositol 2-dehydrogenase activity
BSY16_RS18630	COG1609	Transcriptional regulator
BSY16_RS18640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BSY16_RS18655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS18660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSY16_RS18665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSY16_RS18670	COG1121	(ABC) transporter
BSY16_RS18675	COG0803	Belongs to the bacterial solute-binding protein 9 family
BSY16_RS18685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSY16_RS18690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY16_RS18695	COG3273	potassium ion transport
BSY16_RS18695	COG0471	metal ion transport
BSY16_RS18700	COG1253	flavin adenine dinucleotide binding
BSY16_RS18725	COG0384	phenazine biosynthesis protein PhzF
BSY16_RS18740	COG1070	Carbohydrate kinase
BSY16_RS18745	COG2115	Belongs to the xylose isomerase family
BSY16_RS18750	COG0840	transmembrane signaling receptor activity
BSY16_RS18755	COG1609	Transcriptional regulator
BSY16_RS18760	COG1129	ABC transporter
BSY16_RS18765	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS18770	COG1879	ABC-type sugar transport system periplasmic component
BSY16_RS18780	COG0673	inositol 2-dehydrogenase activity
BSY16_RS18795	COG3300	MHYT domain
BSY16_RS18795	COG5001	Diguanylate cyclase
BSY16_RS18800	COG1054	Belongs to the UPF0176 family
BSY16_RS18805	COG2954	triphosphatase activity
BSY16_RS18810	COG0800	Aldolase
BSY16_RS18830	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BSY16_RS18840	COG0583	DNA-binding transcription factor activity
BSY16_RS18850	COG3153	acetyltransferase
BSY16_RS18855	COG3047	cAMP biosynthetic process
BSY16_RS18860	COG1280	lysine exporter protein (LysE YggA)
BSY16_RS18905	COG5001	Diguanylate cyclase
BSY16_RS18905	COG3300	MHYT domain
BSY16_RS18910	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BSY16_RS18915	COG2814	Major facilitator Superfamily
BSY16_RS18930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSY16_RS18935	COG1609	Transcriptional regulator
BSY16_RS18940	COG1846	Transcriptional regulator
BSY16_RS18950	COG0523	cobalamin synthesis protein
BSY16_RS18970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSY16_RS18975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY16_RS18990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY16_RS18990	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSY16_RS19010	COG1523	belongs to the glycosyl hydrolase 13 family
BSY16_RS19015	COG0033	Phosphoglucomutase
BSY16_RS19020	COG0297	glycogen (starch) synthase activity
BSY16_RS19025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BSY16_RS19030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BSY16_RS19035	COG0058	SHG alpha-glucan phosphorylase activity
BSY16_RS19050	COG2307	Protein conserved in bacteria
BSY16_RS19050	COG2308	Evidence 4 Homologs of previously reported genes of
BSY16_RS19060	COG0840	transmembrane signaling receptor activity
BSY16_RS19085	COG0129	dihydroxy-acid dehydratase activity
BSY16_RS19100	COG2721	sulfolactate sulfo-lyase activity
BSY16_RS19105	COG2186	Transcriptional regulator
BSY16_RS19110	COG4948	Mandelate Racemase Muconate Lactonizing
BSY16_RS19115	COG3275	phosphorelay sensor kinase activity
BSY16_RS19120	COG2233	PERMEase
BSY16_RS19175	COG0067	glutamate synthase
BSY16_RS19175	COG0069	glutamate synthase activity
BSY16_RS19175	COG0070	glutamate synthase
BSY16_RS19190	COG2951	lytic endotransglycosylase activity
BSY16_RS19195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSY16_RS19210	COG1585	Membrane protein implicated in regulation of membrane protease activity
BSY16_RS19215	COG0330	HflC and HflK could
BSY16_RS19220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BSY16_RS19225	COG0737	Belongs to the 5'-nucleotidase family
BSY16_RS19235	COG5310	Homospermidine synthase
BSY16_RS19245	COG1846	Transcriptional regulator
BSY16_RS19255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSY16_RS19255	COG0512	Glutamine amidotransferase of anthranilate synthase
BSY16_RS19270	COG3108	Peptidase M15
BSY16_RS19275	COG3750	Belongs to the UPF0335 family
BSY16_RS19295	COG0469	pyruvate kinase activity
BSY16_RS19305	COG0457	Tetratricopeptide repeat
BSY16_RS19310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSY16_RS19315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSY16_RS19320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BSY16_RS19335	COG0640	Transcriptional regulator
BSY16_RS19355	COG0483	inositol monophosphate 1-phosphatase activity
BSY16_RS19375	COG3181	Tripartite tricarboxylate transporter family receptor
BSY16_RS19385	COG0254	rRNA binding
BSY16_RS19405	COG0126	phosphoglycerate kinase activity
BSY16_RS19450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSY16_RS19465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSY16_RS19470	COG1692	metallophosphoesterase
BSY16_RS19490	COG0217	transcriptional regulatory protein
BSY16_RS19495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY16_RS19500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BSY16_RS19515	COG0632	four-way junction helicase activity
BSY16_RS19520	COG2255	four-way junction helicase activity
BSY16_RS19525	COG1408	metallophosphoesterase
BSY16_RS19530	COG0824	Thioesterase
BSY16_RS19550	COG0823	Involved in the tonB-independent uptake of proteins
BSY16_RS19555	COG2885	chlorophyll binding
BSY16_RS19565	COG0037	tRNA processing
BSY16_RS19570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSY16_RS19575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSY16_RS19590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSY16_RS19595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY16_RS19600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY16_RS19620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSY16_RS19625	COG0840	transmembrane signaling receptor activity
BSY16_RS19635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSY16_RS19645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY16_RS19650	COG0564	pseudouridine synthase activity
BSY16_RS19700	COG2995	paraquat-inducible protein a
BSY16_RS19710	COG2197	response regulator
BSY16_RS19715	COG0482	sulfurtransferase activity
BSY16_RS19725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSY16_RS19790	COG0328	RNA-DNA hybrid ribonuclease activity
BSY16_RS20015	COG3273	potassium ion transport
BSY16_RS20015	COG0471	metal ion transport
BSY16_RS20055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY16_RS20345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY16_RS20345	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSY16_RS20385	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS20450	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSY16_RS20510	COG0804	urea catabolic process
BSY16_RS21210	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BSY16_RS21220	COG2195	Cleaves the N-terminal amino acid of tripeptides
BSY16_RS21270	COG0651	ATP synthesis coupled electron transport
BSY16_RS21410	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY16_RS21775	COG0830	nickel cation binding
BSY16_RS21995	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BSY16_RS22225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSY16_RS22395	COG2308	Evidence 4 Homologs of previously reported genes of
BSY16_RS22415	COG4335	DNA alkylation repair
BSY16_RS22585	COG1473	amidohydrolase
BSY16_RS22610	COG0366	Alpha amylase catalytic
BSY16_RS22965	COG1012	belongs to the aldehyde dehydrogenase family
BSY16_RS23255	COG0505	Belongs to the CarA family
BSY16_RS23285	COG0514	ATP-dependent DNA helicase (RecQ)
BSY16_RS23860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSY16_RS23930	COG3842	ATPase activity
BSY16_RS24050	COG0488	(ABC) transporter
BSY16_RS24090	COG5001	Diguanylate cyclase
BSY16_RS24170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSY16_RS24195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSY16_RS24275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSY16_RS24295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSY16_RS24445	COG1175	transmembrane transport
BSY16_RS24490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY16_RS24795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSY16_RS24860	COG0745	RESPONSE REGULATOR receiver
BSY16_RS24955	COG2304	oxidoreductase activity
BSY16_RS25235	COG3250	beta-galactosidase activity
BSY16_RS25305	COG2084	Dehydrogenase
BSY16_RS25515	COG1368	sulfuric ester hydrolase activity
BSY16_RS25775	COG0306	phosphate transporter
BSY16_RS25950	COG0582	viral genome integration into host DNA
BSY16_RS26030	COG0525	valine-tRNA ligase activity
BSY16_RS26070	COG0018	arginyl-trna synthetase
BSY16_RS26245	COG0504	CTP synthase activity
BSY16_RS26345	COG5000	phosphorelay sensor kinase activity
BSY16_RS26395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSY16_RS26395	COG1648	precorrin-2 dehydrogenase activity
BSY16_RS27420	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY16_RS27420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY16_RS27595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSY16_RS27660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSY16_RS27675	COG2814	Major facilitator Superfamily
BSY16_RS28070	COG0085	RNA polymerase activity
BSY16_RS28320	COG0557	exoribonuclease II activity
BSY16_RS28955	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSY16_RS28980	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BSY16_RS29235	COG2233	PERMEase
BSY16_RS29400	COG0215	cysteine-tRNA ligase activity
BSY16_RS29530	COG5001	Diguanylate cyclase
BSY16_RS29975	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSY16_RS30005	COG1138	Cytochrome C-type biogenesis protein
BSY16_RS30280	COG4993	Dehydrogenase
BSY16_RS30855	COG0668	transmembrane transport
BSY16_RS30930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY16_RS31140	COG1960	acyl-CoA dehydrogenase activity