locus-tag	class	description
CA265_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CA265_RS00010	COG0494	nUDIX hydrolase
CA265_RS00035	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CA265_RS00085	COG2354	Protein conserved in bacteria
CA265_RS00125	COG0726	polysaccharide deacetylase
CA265_RS00130	COG0463	Glycosyl transferase, family 2
CA265_RS00145	COG4771	TonB-dependent receptor
CA265_RS00160	COG1595	DNA-templated transcription, initiation
CA265_RS00170	COG1629	transport
CA265_RS00175	COG0702	epimerase
CA265_RS00180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS00185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS00215	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CA265_RS00225	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CA265_RS00240	COG2205	protein histidine kinase activity
CA265_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS00280	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CA265_RS00280	COG3264	Mechanosensitive ion channel
CA265_RS00295	COG2378	regulation of single-species biofilm formation
CA265_RS00305	COG1733	regulation of RNA biosynthetic process
CA265_RS00310	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS00315	COG3279	Response regulator of the LytR AlgR family
CA265_RS00330	COG2909	trisaccharide binding
CA265_RS00365	COG5002	protein histidine kinase activity
CA265_RS00370	COG0745	RESPONSE REGULATOR receiver
CA265_RS00400	COG3275	phosphorelay sensor kinase activity
CA265_RS00405	COG3279	Response regulator of the LytR AlgR family
CA265_RS00410	COG0492	ferredoxin-NADP+ reductase activity
CA265_RS00410	COG3118	belongs to the thioredoxin family
CA265_RS00430	COG0656	L-ascorbic acid biosynthetic process
CA265_RS00435	COG0667	Aldo Keto reductase
CA265_RS00460	COG1073	alpha beta
CA265_RS00520	COG3708	Transcriptional regulator
CA265_RS00520	COG2207	Transcriptional regulator
CA265_RS00525	COG0667	Aldo Keto reductase
CA265_RS00580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CA265_RS00580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CA265_RS00590	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CA265_RS00600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CA265_RS00605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CA265_RS00615	COG2132	Multicopper oxidase
CA265_RS00645	COG2814	Major facilitator Superfamily
CA265_RS00685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CA265_RS00710	COG3292	Two component regulator propeller
CA265_RS00710	COG2205	protein histidine kinase activity
CA265_RS00710	COG0745	RESPONSE REGULATOR receiver
CA265_RS00715	COG4771	TonB-dependent receptor
CA265_RS00720	COG0702	epimerase
CA265_RS00725	COG1629	transport
CA265_RS00730	COG0702	epimerase
CA265_RS00740	COG5492	domain, Protein
CA265_RS00745	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CA265_RS00755	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CA265_RS00760	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS00775	COG0288	reversible hydration of carbon dioxide
CA265_RS00780	COG0655	NAD(P)H dehydrogenase (quinone) activity
CA265_RS00815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS00820	COG4771	TonB-dependent receptor
CA265_RS00825	COG0702	epimerase
CA265_RS00860	COG1629	transport
CA265_RS00890	COG1609	Transcriptional regulator
CA265_RS00900	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CA265_RS00945	COG4771	TonB-dependent receptor
CA265_RS00950	COG0702	epimerase
CA265_RS00955	COG0667	Aldo Keto reductase
CA265_RS00960	COG4771	TonB-dependent receptor
CA265_RS00970	COG1609	Transcriptional regulator
CA265_RS01020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CA265_RS01030	COG4166	transmembrane transport
CA265_RS01040	COG2204	response regulator
CA265_RS01050	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA265_RS01060	COG3537	Alpha-1,2-mannosidase
CA265_RS01075	COG4335	DNA alkylation repair
CA265_RS01090	COG0730	response to heat
CA265_RS01095	COG2186	Transcriptional regulator
CA265_RS01125	COG2610	gluconate transmembrane transporter activity
CA265_RS01140	COG4181	ATPase activity
CA265_RS01155	COG1858	cytochrome C peroxidase
CA265_RS01235	COG4989	oxidoreductase activity
CA265_RS01245	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA265_RS01255	COG2207	Transcriptional regulator
CA265_RS01255	COG0662	Cupin 2, conserved barrel domain protein
CA265_RS01265	COG2188	Transcriptional regulator
CA265_RS01275	COG2814	Major facilitator Superfamily
CA265_RS01315	COG5434	Belongs to the glycosyl hydrolase 28 family
CA265_RS01345	COG4191	Histidine kinase
CA265_RS01360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CA265_RS01375	COG3278	Belongs to the heme-copper respiratory oxidase family
CA265_RS01435	COG4771	TonB-dependent receptor
CA265_RS01455	COG2814	Major facilitator Superfamily
CA265_RS01480	COG3437	response regulator, receiver
CA265_RS01485	COG2205	protein histidine kinase activity
CA265_RS01485	COG3292	Two component regulator propeller
CA265_RS01485	COG0745	RESPONSE REGULATOR receiver
CA265_RS01490	COG4771	TonB-dependent receptor
CA265_RS01510	COG3940	Belongs to the glycosyl hydrolase 43 family
CA265_RS01520	COG3250	beta-galactosidase activity
CA265_RS01530	COG0457	Tetratricopeptide repeat
CA265_RS01545	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CA265_RS01545	COG3264	Mechanosensitive ion channel
CA265_RS01555	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CA265_RS01560	COG4251	negative regulation of phosphorylation
CA265_RS01565	COG4251	negative regulation of phosphorylation
CA265_RS01570	COG5002	protein histidine kinase activity
CA265_RS01580	COG4948	Mandelate Racemase Muconate Lactonizing
CA265_RS01610	COG3340	Belongs to the peptidase S51 family
CA265_RS01620	COG0110	maltose O-acetyltransferase activity
CA265_RS01645	COG0438	transferase activity, transferring glycosyl groups
CA265_RS01665	COG2755	lipolytic protein G-D-S-L family
CA265_RS01665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CA265_RS01670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA265_RS01675	COG1216	Glycosyl transferase, family 2
CA265_RS01705	COG0463	Glycosyl transferase, family 2
CA265_RS01760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CA265_RS01765	COG2226	methyltransferase
CA265_RS01775	COG1215	transferase activity, transferring glycosyl groups
CA265_RS01805	COG0438	transferase activity, transferring glycosyl groups
CA265_RS01810	COG0367	asparagine synthase
CA265_RS01820	COG0489	protein tyrosine kinase activity
CA265_RS01860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CA265_RS01880	COG0126	phosphoglycerate kinase activity
CA265_RS01915	COG4771	TonB-dependent receptor
CA265_RS01925	COG3119	arylsulfatase activity
CA265_RS01935	COG1629	transport
CA265_RS01960	COG2001	Belongs to the MraZ family
CA265_RS01965	COG0275	rRNA processing
CA265_RS01975	COG0768	penicillin binding
CA265_RS01980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CA265_RS01985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CA265_RS01990	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CA265_RS01995	COG0772	Belongs to the SEDS family
CA265_RS02000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CA265_RS02005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CA265_RS02020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CA265_RS02025	COG0156	8-amino-7-oxononanoate synthase activity
CA265_RS02050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CA265_RS02055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CA265_RS02070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CA265_RS02090	COG1136	(ABC) transporter
CA265_RS02115	COG0735	belongs to the Fur family
CA265_RS02145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CA265_RS02195	COG0205	6-phosphofructokinase activity
CA265_RS02215	COG0439	Biotin carboxylase
CA265_RS02220	COG0307	riboflavin synthase, alpha
CA265_RS02225	COG3408	Glycogen debranching enzyme
CA265_RS02275	COG2197	response regulator
CA265_RS02360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CA265_RS02385	COG0360	Binds together with S18 to 16S ribosomal RNA
CA265_RS02390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CA265_RS02395	COG0359	binds to the 23S rRNA
CA265_RS02405	COG4221	oxidoreductase activity
CA265_RS02415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CA265_RS02450	COG2181	nitrate reductase activity
CA265_RS02450	COG0247	lactate metabolic process
CA265_RS02455	COG0247	lactate metabolic process
CA265_RS02455	COG2181	nitrate reductase activity
CA265_RS02475	COG1917	Cupin 2, conserved barrel domain protein
CA265_RS02475	COG4977	sequence-specific DNA binding
CA265_RS02485	COG3292	Two component regulator propeller
CA265_RS02485	COG2205	protein histidine kinase activity
CA265_RS02485	COG0745	RESPONSE REGULATOR receiver
CA265_RS02485	COG3292	Two component regulator propeller
CA265_RS02485	COG2205	protein histidine kinase activity
CA265_RS02485	COG0745	RESPONSE REGULATOR receiver
CA265_RS02510	COG4771	TonB-dependent receptor
CA265_RS02515	COG0702	epimerase
CA265_RS02585	COG1629	transport
CA265_RS02590	COG0702	epimerase
CA265_RS02595	COG1785	Belongs to the alkaline phosphatase family
CA265_RS02605	COG3275	phosphorelay sensor kinase activity
CA265_RS02610	COG3279	Response regulator of the LytR AlgR family
CA265_RS02630	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS02630	COG3347	Dehydrogenase
CA265_RS02635	COG4952	isomerase
CA265_RS02640	COG1070	Carbohydrate kinase
CA265_RS02655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA265_RS02670	COG1435	thymidine kinase activity
CA265_RS02680	COG0772	Belongs to the SEDS family
CA265_RS02685	COG0768	penicillin binding
CA265_RS02700	COG1077	Cell shape determining protein MreB Mrl
CA265_RS02705	COG0138	bifunctional purine biosynthesis protein purh
CA265_RS02710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CA265_RS02715	COG0268	Binds directly to 16S ribosomal RNA
CA265_RS02720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS02725	COG2003	Belongs to the UPF0758 family
CA265_RS02770	COG1418	mRNA catabolic process
CA265_RS02820	COG1960	acyl-CoA dehydrogenase activity
CA265_RS02830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CA265_RS02835	COG4974	Belongs to the 'phage' integrase family
CA265_RS02885	COG1876	peptidase activity
CA265_RS02895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CA265_RS02900	COG0081	regulation of translation
CA265_RS02905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CA265_RS02910	COG0222	ribosome binding
CA265_RS02915	COG0085	RNA polymerase activity
CA265_RS02920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CA265_RS02925	COG3119	arylsulfatase activity
CA265_RS02935	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CA265_RS02960	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CA265_RS02970	COG0517	IMP dehydrogenase activity
CA265_RS02970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CA265_RS02970	COG0617	tRNA 3'-terminal CCA addition
CA265_RS02975	COG0009	L-threonylcarbamoyladenylate synthase
CA265_RS02990	COG0438	transferase activity, transferring glycosyl groups
CA265_RS03015	COG0590	tRNA wobble adenosine to inosine editing
CA265_RS03030	COG0187	DNA topoisomerase II activity
CA265_RS03035	COG1695	Transcriptional regulator
CA265_RS03045	COG3781	membrane
CA265_RS03055	COG5002	protein histidine kinase activity
CA265_RS03060	COG0745	RESPONSE REGULATOR receiver
CA265_RS03095	COG3118	belongs to the thioredoxin family
CA265_RS03100	COG2133	pyrroloquinoline quinone binding
CA265_RS03115	COG0450	alkyl hydroperoxide reductase
CA265_RS03120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CA265_RS03120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CA265_RS03130	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CA265_RS03145	COG0179	Fumarylacetoacetate (FAA) hydrolase
CA265_RS03170	COG4221	oxidoreductase activity
CA265_RS03195	COG0791	NLP P60 protein
CA265_RS03200	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS03220	COG0423	glycine-tRNA ligase activity
CA265_RS03245	COG4585	Histidine kinase
CA265_RS03250	COG2197	response regulator
CA265_RS03255	COG0584	glycerophosphoryl diester phosphodiesterase
CA265_RS03315	COG0586	Pfam SNARE associated Golgi protein
CA265_RS03335	COG2852	Protein conserved in bacteria
CA265_RS03340	COG2852	Protein conserved in bacteria
CA265_RS03365	COG0443	Heat shock 70 kDa protein
CA265_RS03390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CA265_RS03395	COG0513	Belongs to the DEAD box helicase family
CA265_RS03430	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CA265_RS03445	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CA265_RS03455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CA265_RS03475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CA265_RS03510	COG0633	Ferredoxin
CA265_RS03535	COG0424	maF-like protein
CA265_RS03545	COG0248	Ppx GppA phosphatase
CA265_RS03555	COG0484	heat shock protein binding
CA265_RS03560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CA265_RS03565	COG2884	Cell division ATP-binding protein ftsE
CA265_RS03585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CA265_RS03605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CA265_RS03605	COG0140	phosphoribosyl-ATP diphosphatase activity
CA265_RS03610	COG0107	imidazoleglycerol-phosphate synthase activity
CA265_RS03615	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CA265_RS03620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CA265_RS03625	COG0131	Imidazoleglycerol-phosphate dehydratase
CA265_RS03625	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CA265_RS03630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CA265_RS03640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CA265_RS03645	COG2989	Protein conserved in bacteria
CA265_RS03655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CA265_RS03660	COG1397	ADP-ribosylglycohydrolase
CA265_RS03680	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CA265_RS03690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CA265_RS03725	COG0463	Glycosyl transferase, family 2
CA265_RS03750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CA265_RS03755	COG0750	zinc metalloprotease
CA265_RS03765	COG2814	Major facilitator Superfamily
CA265_RS03770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CA265_RS03800	COG1309	transcriptional regulator
CA265_RS03820	COG0402	S-adenosylhomocysteine deaminase activity
CA265_RS03880	COG0714	Associated with various cellular activities
CA265_RS03890	COG1522	sequence-specific DNA binding
CA265_RS03895	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CA265_RS03915	COG4529	Protein conserved in bacteria
CA265_RS03920	COG4771	TonB-dependent receptor
CA265_RS03925	COG0702	epimerase
CA265_RS03930	COG1629	transport
CA265_RS03930	COG4206	TonB-dependent receptor
CA265_RS03945	COG0561	phosphatase activity
CA265_RS03960	COG4771	TonB-dependent receptor
CA265_RS04015	COG2274	protein secretion by the type I secretion system
CA265_RS04020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA265_RS04025	COG3250	beta-galactosidase activity
CA265_RS04030	COG3345	alpha-galactosidase
CA265_RS04065	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CA265_RS04075	COG0076	glutamate decarboxylase activity
CA265_RS04090	COG1959	2 iron, 2 sulfur cluster binding
CA265_RS04095	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CA265_RS04100	COG1648	precorrin-2 dehydrogenase activity
CA265_RS04100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CA265_RS04105	COG0730	response to heat
CA265_RS04110	COG0175	sulfate reduction
CA265_RS04120	COG2895	sulfate adenylyltransferase (ATP) activity
CA265_RS04135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CA265_RS04140	COG0297	glycogen (starch) synthase activity
CA265_RS04145	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CA265_RS04150	COG3387	PFAM Glycoside hydrolase 15-related
CA265_RS04155	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CA265_RS04160	COG4191	Histidine kinase
CA265_RS04165	COG2204	response regulator
CA265_RS04175	COG1136	(ABC) transporter
CA265_RS04180	COG0577	efflux transmembrane transporter activity
CA265_RS04190	COG0577	efflux transmembrane transporter activity
CA265_RS04190	COG1136	(ABC) transporter
CA265_RS04195	COG0577	efflux transmembrane transporter activity
CA265_RS04200	COG0577	efflux transmembrane transporter activity
CA265_RS04200	COG1136	(ABC) transporter
CA265_RS04225	COG4948	Mandelate Racemase Muconate Lactonizing
CA265_RS04240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CA265_RS04260	COG0544	peptidyl-prolyl cis-trans isomerase activity
CA265_RS04275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CA265_RS04280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CA265_RS04285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CA265_RS04295	COG3655	Transcriptional regulator
CA265_RS04300	COG0045	succinate-CoA ligase (ADP-forming) activity
CA265_RS04345	COG1136	(ABC) transporter
CA265_RS04370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CA265_RS04370	COG0758	DNA mediated transformation
CA265_RS04380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CA265_RS04405	COG1796	DNA polymerase
CA265_RS04405	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CA265_RS04415	COG0616	signal peptide processing
CA265_RS04420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CA265_RS04420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CA265_RS04430	COG1183	phosphatidylcholine synthase activity
CA265_RS04435	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CA265_RS04440	COG0284	orotidine-5'-phosphate decarboxylase activity
CA265_RS04475	COG1674	ftsk spoiiie
CA265_RS04490	COG0321	lipoyl(octanoyl) transferase activity
CA265_RS04490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CA265_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS04525	COG3279	Response regulator of the LytR AlgR family
CA265_RS04535	COG0288	reversible hydration of carbon dioxide
CA265_RS04650	COG5002	protein histidine kinase activity
CA265_RS04665	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS04670	COG2721	sulfolactate sulfo-lyase activity
CA265_RS04675	COG0738	Major facilitator superfamily
CA265_RS04690	COG4977	sequence-specific DNA binding
CA265_RS04730	COG4447	cellulose binding
CA265_RS04735	COG0861	Integral membrane protein TerC family
CA265_RS04800	COG0628	permease
CA265_RS04810	COG0745	RESPONSE REGULATOR receiver
CA265_RS04820	COG2186	Transcriptional regulator
CA265_RS04825	COG4771	TonB-dependent receptor
CA265_RS04840	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CA265_RS04845	COG2271	Major facilitator Superfamily
CA265_RS04945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CA265_RS04970	COG1611	Belongs to the LOG family
CA265_RS04975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA265_RS04980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CA265_RS04990	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS05010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CA265_RS05015	COG0135	phosphoribosylanthranilate isomerase activity
CA265_RS05020	COG0133	tryptophan synthase activity
CA265_RS05025	COG0159	tryptophan synthase activity
CA265_RS05040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA265_RS05070	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CA265_RS05100	COG0009	L-threonylcarbamoyladenylate synthase
CA265_RS05105	COG0069	glutamate synthase activity
CA265_RS05115	COG0017	Asparaginyl-tRNA synthetase
CA265_RS05130	COG2308	Evidence 4 Homologs of previously reported genes of
CA265_RS05135	COG1528	Iron-storage protein
CA265_RS05145	COG0456	acetyltransferase
CA265_RS05150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CA265_RS05155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA265_RS05175	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CA265_RS05185	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CA265_RS05195	COG0047	phosphoribosylformylglycinamidine synthase activity
CA265_RS05195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CA265_RS05200	COG0346	lactoylglutathione lyase activity
CA265_RS05210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CA265_RS05220	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CA265_RS05225	COG0328	RNA-DNA hybrid ribonuclease activity
CA265_RS05240	COG5002	protein histidine kinase activity
CA265_RS05255	COG5002	protein histidine kinase activity
CA265_RS05265	COG2755	lipolytic protein G-D-S-L family
CA265_RS05265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CA265_RS05285	COG4771	TonB-dependent receptor
CA265_RS05290	COG0702	epimerase
CA265_RS05300	COG1501	Belongs to the glycosyl hydrolase 31 family
CA265_RS05305	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CA265_RS05340	COG1609	Transcriptional regulator
CA265_RS05355	COG0702	epimerase
CA265_RS05360	COG4771	TonB-dependent receptor
CA265_RS05385	COG1629	transport
CA265_RS05400	COG3119	arylsulfatase activity
CA265_RS05400	COG3408	Glycogen debranching enzyme
CA265_RS05440	COG2353	YceI-like domain
CA265_RS05445	COG1629	transport
CA265_RS05460	COG0488	(ABC) transporter
CA265_RS05465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CA265_RS05470	COG4771	TonB-dependent receptor
CA265_RS05475	COG0702	epimerase
CA265_RS05480	COG3119	arylsulfatase activity
CA265_RS05500	COG5492	domain, Protein
CA265_RS05510	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CA265_RS05535	COG4771	TonB-dependent receptor
CA265_RS05545	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CA265_RS05555	COG1629	transport
CA265_RS05585	COG1764	response to oxidative stress
CA265_RS05590	COG0596	Alpha beta hydrolase
CA265_RS05600	COG0488	(ABC) transporter
CA265_RS05605	COG3275	phosphorelay sensor kinase activity
CA265_RS05610	COG3279	Response regulator of the LytR AlgR family
CA265_RS05625	COG2855	membrane
CA265_RS05660	COG3279	Response regulator of the LytR AlgR family
CA265_RS05665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA265_RS05675	COG0006	proline dipeptidase activity
CA265_RS05690	COG0006	proline dipeptidase activity
CA265_RS05700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CA265_RS05710	COG3938	Belongs to the proline racemase family
CA265_RS05715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA265_RS05730	COG2003	Belongs to the UPF0758 family
CA265_RS05740	COG1917	Cupin 2, conserved barrel domain protein
CA265_RS05750	COG0531	amino acid
CA265_RS05785	COG0745	RESPONSE REGULATOR receiver
CA265_RS05785	COG3292	Two component regulator propeller
CA265_RS05785	COG2205	protein histidine kinase activity
CA265_RS05790	COG4771	TonB-dependent receptor
CA265_RS05795	COG0702	epimerase
CA265_RS05815	COG3119	arylsulfatase activity
CA265_RS05870	COG1368	sulfuric ester hydrolase activity
CA265_RS05880	COG0745	RESPONSE REGULATOR receiver
CA265_RS05885	COG3850	Histidine kinase
CA265_RS05885	COG5002	protein histidine kinase activity
CA265_RS05890	COG0671	phosphoesterase, PA-phosphatase related
CA265_RS05905	COG3179	chitinase
CA265_RS05930	COG0673	inositol 2-dehydrogenase activity
CA265_RS05960	COG4221	oxidoreductase activity
CA265_RS06035	COG5002	protein histidine kinase activity
CA265_RS06050	COG3292	Two component regulator propeller
CA265_RS06050	COG2205	protein histidine kinase activity
CA265_RS06050	COG3292	Two component regulator propeller
CA265_RS06050	COG0745	RESPONSE REGULATOR receiver
CA265_RS06050	COG0745	RESPONSE REGULATOR receiver
CA265_RS06050	COG2205	protein histidine kinase activity
CA265_RS06060	COG3507	Belongs to the glycosyl hydrolase 43 family
CA265_RS06085	COG4771	TonB-dependent receptor
CA265_RS06090	COG0702	epimerase
CA265_RS06100	COG0702	epimerase
CA265_RS06120	COG1085	galactose-1-phosphate uridylyltransferase
CA265_RS06125	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CA265_RS06135	COG0025	NhaP-type Na H and K H
CA265_RS06145	COG3250	beta-galactosidase activity
CA265_RS06160	COG2885	chlorophyll binding
CA265_RS06195	COG0163	prenyltransferase activity
CA265_RS06200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CA265_RS06215	COG0483	inositol monophosphate 1-phosphatase activity
CA265_RS06220	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CA265_RS06255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA265_RS06260	COG0450	alkyl hydroperoxide reductase
CA265_RS06275	COG0527	aspartate kinase activity
CA265_RS06280	COG1247	-acetyltransferase
CA265_RS06285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CA265_RS06295	COG1193	negative regulation of DNA recombination
CA265_RS06300	COG2133	pyrroloquinoline quinone binding
CA265_RS06305	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CA265_RS06315	COG0572	uridine kinase
CA265_RS06320	COG1388	LysM domain
CA265_RS06320	COG0791	NLP P60 protein
CA265_RS06325	COG0783	Belongs to the Dps family
CA265_RS06370	COG0442	prolyl-tRNA aminoacylation
CA265_RS06375	COG0626	cystathionine gamma-synthase activity
CA265_RS06400	COG2197	response regulator
CA265_RS06540	COG2885	chlorophyll binding
CA265_RS06545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CA265_RS06565	COG0463	Glycosyl transferase, family 2
CA265_RS06570	COG3104	oligopeptide transport
CA265_RS06575	COG3104	oligopeptide transport
CA265_RS06580	COG3104	oligopeptide transport
CA265_RS06590	COG0183	Belongs to the thiolase family
CA265_RS06610	COG1480	7TM receptor with intracellular HD hydrolase
CA265_RS06650	COG5002	protein histidine kinase activity
CA265_RS06660	COG4106	trans-aconitate 2-methyltransferase activity
CA265_RS06685	COG4771	TonB-dependent receptor
CA265_RS06690	COG0702	epimerase
CA265_RS06715	COG0671	phosphoesterase, PA-phosphatase related
CA265_RS06735	COG0702	epimerase
CA265_RS06740	COG4206	TonB-dependent receptor
CA265_RS06740	COG1629	transport
CA265_RS06780	COG2205	protein histidine kinase activity
CA265_RS06780	COG3292	Two component regulator propeller
CA265_RS06780	COG0745	RESPONSE REGULATOR receiver
CA265_RS06790	COG5492	domain, Protein
CA265_RS06795	COG4771	TonB-dependent receptor
CA265_RS06810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CA265_RS06845	COG0492	ferredoxin-NADP+ reductase activity
CA265_RS06890	COG0346	lactoylglutathione lyase activity
CA265_RS06950	COG0667	Aldo Keto reductase
CA265_RS06960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA265_RS07080	COG4953	penicillin-binding protein 1C
CA265_RS07095	COG2373	Large extracellular alpha-helical protein
CA265_RS07115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CA265_RS07115	COG1754	DNA topoisomerase type I activity
CA265_RS07120	COG0386	Belongs to the glutathione peroxidase family
CA265_RS07130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CA265_RS07145	COG1609	Transcriptional regulator
CA265_RS07150	COG1629	transport
CA265_RS07150	COG4206	TonB-dependent receptor
CA265_RS07160	COG1629	transport
CA265_RS07165	COG0702	epimerase
CA265_RS07170	COG3250	beta-galactosidase activity
CA265_RS07185	COG3250	beta-galactosidase activity
CA265_RS07195	COG3250	beta-galactosidase activity
CA265_RS07205	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CA265_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS07225	COG1312	Catalyzes the dehydration of D-mannonate
CA265_RS07280	COG4932	domain protein
CA265_RS07280	COG3266	domain, Protein
CA265_RS07280	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CA265_RS07340	COG5002	protein histidine kinase activity
CA265_RS07345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA265_RS07380	COG4771	TonB-dependent receptor
CA265_RS07395	COG4771	TonB-dependent receptor
CA265_RS07405	COG0700	Nucleoside recognition
CA265_RS07415	COG0706	membrane insertase activity
CA265_RS07420	COG0504	CTP synthase activity
CA265_RS07450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CA265_RS07460	COG1428	Deoxynucleoside kinase
CA265_RS07465	COG0180	Tryptophanyl-tRNA synthetase
CA265_RS07480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CA265_RS07485	COG1136	(ABC) transporter
CA265_RS07500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CA265_RS07505	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CA265_RS07510	COG1136	(ABC) transporter
CA265_RS07510	COG0577	efflux transmembrane transporter activity
CA265_RS07530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CA265_RS07540	COG0640	Transcriptional regulator
CA265_RS07560	COG1199	ATP-dependent helicase activity
CA265_RS07560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CA265_RS07570	COG0745	RESPONSE REGULATOR receiver
CA265_RS07575	COG3279	Response regulator of the LytR AlgR family
CA265_RS07585	COG3279	Response regulator of the LytR AlgR family
CA265_RS07605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CA265_RS07645	COG2201	protein-glutamate methylesterase activity
CA265_RS07665	COG0702	epimerase
CA265_RS07695	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CA265_RS07705	COG3153	acetyltransferase
CA265_RS07705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA265_RS07710	COG2255	four-way junction helicase activity
CA265_RS07715	COG1250	3-hydroxyacyl-CoA dehydrogenase
CA265_RS07720	COG0259	pyridoxamine-phosphate oxidase activity
CA265_RS07725	COG1678	Uncharacterized ACR, COG1678
CA265_RS07735	COG3655	Transcriptional regulator
CA265_RS07740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CA265_RS07745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CA265_RS07750	COG2081	HI0933 family
CA265_RS07780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CA265_RS07795	COG2270	Major facilitator Superfamily
CA265_RS07810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CA265_RS07810	COG2755	lipolytic protein G-D-S-L family
CA265_RS07815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CA265_RS07820	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CA265_RS07825	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CA265_RS07830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CA265_RS07855	COG0612	Peptidase, M16
CA265_RS07865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CA265_RS07870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CA265_RS07880	COG1349	DNA-binding transcription factor activity
CA265_RS07885	COG0745	RESPONSE REGULATOR receiver
CA265_RS07900	COG0489	protein tyrosine kinase activity
CA265_RS07900	COG3206	protein involved in exopolysaccharide biosynthesis
CA265_RS07910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CA265_RS07915	COG2244	polysaccharide biosynthetic process
CA265_RS07930	COG0438	transferase activity, transferring glycosyl groups
CA265_RS07940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CA265_RS07945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CA265_RS07950	COG0438	transferase activity, transferring glycosyl groups
CA265_RS07955	COG0367	asparagine synthase
CA265_RS07965	COG0438	transferase activity, transferring glycosyl groups
CA265_RS07995	COG0456	acetyltransferase
CA265_RS08030	COG0604	alcohol dehydrogenase
CA265_RS08075	COG1295	ribonuclease BN
CA265_RS08095	COG1181	Belongs to the D-alanine--D-alanine ligase family
CA265_RS08120	COG3142	Participates in the control of copper homeostasis
CA265_RS08130	COG1446	asparaginase
CA265_RS08135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA265_RS08140	COG0436	Aminotransferase
CA265_RS08145	COG1477	protein flavinylation
CA265_RS08155	COG2814	Major facilitator Superfamily
CA265_RS08160	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CA265_RS08175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CA265_RS08200	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CA265_RS08210	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CA265_RS08220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CA265_RS08225	COG0791	NLP P60 protein
CA265_RS08230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS08285	COG3591	Belongs to the peptidase S1B family
CA265_RS08285	COG1864	DNA RNA non-specific endonuclease
CA265_RS08300	COG4585	Histidine kinase
CA265_RS08325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA265_RS08335	COG1304	FMN binding
CA265_RS08345	COG3254	rhamnose metabolic process
CA265_RS08350	COG0179	Fumarylacetoacetate (FAA) hydrolase
CA265_RS08355	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS08385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA265_RS08390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CA265_RS08395	COG2169	Transcriptional regulator
CA265_RS08410	COG1629	transport
CA265_RS08415	COG0702	epimerase
CA265_RS08425	COG1629	transport
CA265_RS08430	COG0702	epimerase
CA265_RS08475	COG3250	beta-galactosidase activity
CA265_RS08480	COG3250	beta-galactosidase activity
CA265_RS08500	COG1082	Xylose isomerase domain protein TIM barrel
CA265_RS08510	COG0673	inositol 2-dehydrogenase activity
CA265_RS08525	COG1414	Transcriptional regulator
CA265_RS08530	COG3408	Glycogen debranching enzyme
CA265_RS08540	COG3250	beta-galactosidase activity
CA265_RS08550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CA265_RS08555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CA265_RS08565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CA265_RS08570	COG1607	acyl-coa hydrolase
CA265_RS08575	COG0738	Major facilitator superfamily
CA265_RS08580	COG3940	Belongs to the glycosyl hydrolase 43 family
CA265_RS08585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CA265_RS08605	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS08610	COG1063	alcohol dehydrogenase
CA265_RS08615	COG2160	L-arabinose isomerase activity
CA265_RS08620	COG0235	Class ii aldolase
CA265_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS08670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CA265_RS08680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CA265_RS08685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CA265_RS08700	COG0067	glutamate synthase
CA265_RS08700	COG0069	glutamate synthase activity
CA265_RS08700	COG0070	glutamate synthase
CA265_RS08720	COG5002	protein histidine kinase activity
CA265_RS08730	COG0438	transferase activity, transferring glycosyl groups
CA265_RS08735	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CA265_RS08750	COG0668	transmembrane transport
CA265_RS08755	COG0745	RESPONSE REGULATOR receiver
CA265_RS08760	COG4251	negative regulation of phosphorylation
CA265_RS08765	COG0745	RESPONSE REGULATOR receiver
CA265_RS08795	COG4771	TonB-dependent receptor
CA265_RS08805	COG1609	Transcriptional regulator
CA265_RS08825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CA265_RS08855	COG2211	Major facilitator Superfamily
CA265_RS08865	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CA265_RS08870	COG2086	electron transfer activity
CA265_RS08885	COG0305	Participates in initiation and elongation during chromosome replication
CA265_RS08890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA265_RS08900	COG0517	IMP dehydrogenase activity
CA265_RS08900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CA265_RS08905	COG0514	ATP-dependent DNA helicase (RecQ)
CA265_RS08910	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CA265_RS08930	COG0602	queuosine metabolic process
CA265_RS08950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CA265_RS08955	COG0481	GTPase activity
CA265_RS08965	COG0824	Thioesterase
CA265_RS08980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CA265_RS08985	COG1185	polyribonucleotide nucleotidyltransferase activity
CA265_RS08990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CA265_RS09005	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CA265_RS09010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CA265_RS09025	COG1702	phosphate starvation-inducible protein PhoH
CA265_RS09030	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CA265_RS09040	COG1234	tRNA 3'-trailer cleavage
CA265_RS09050	COG1388	LysM domain
CA265_RS09050	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA265_RS09055	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA265_RS09065	COG1546	Belongs to the CinA family
CA265_RS09065	COG1058	Belongs to the CinA family
CA265_RS09070	COG0508	dehydrogenase complex catalyzes the overall conversion of
CA265_RS09080	COG3118	belongs to the thioredoxin family
CA265_RS09090	COG1201	RNA secondary structure unwinding
CA265_RS09095	COG1793	dna ligase
CA265_RS09130	COG2333	competence protein COMEC
CA265_RS09130	COG0658	competence protein
CA265_RS09145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CA265_RS09170	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CA265_RS09175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS09180	COG0745	RESPONSE REGULATOR receiver
CA265_RS09185	COG0564	pseudouridine synthase activity
CA265_RS09250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CA265_RS09280	COG1956	GAF domain-containing protein
CA265_RS09285	COG2094	Belongs to the DNA glycosylase MPG family
CA265_RS09295	COG3844	kynureninase activity
CA265_RS09300	COG3781	membrane
CA265_RS09305	COG0123	including yeast histone deacetylase and acetoin utilization protein
CA265_RS09325	COG0534	Mate efflux family protein
CA265_RS09345	COG2814	Major facilitator Superfamily
CA265_RS09350	COG0408	coproporphyrinogen oxidase activity
CA265_RS09355	COG1515	deoxyribonuclease V activity
CA265_RS09440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CA265_RS09450	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CA265_RS09455	COG1289	transmembrane transporter activity
CA265_RS09470	COG1764	response to oxidative stress
CA265_RS09475	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CA265_RS09480	COG2239	Acts as a magnesium transporter
CA265_RS09490	COG3609	addiction module antidote protein, CC2985 family
CA265_RS09495	COG0598	Magnesium transport protein CorA
CA265_RS09510	COG1216	Glycosyl transferase, family 2
CA265_RS09515	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CA265_RS09520	COG4974	Belongs to the 'phage' integrase family
CA265_RS09525	COG2890	protein-(glutamine-N5) methyltransferase activity
CA265_RS09530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CA265_RS09530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CA265_RS09535	COG0697	spore germination
CA265_RS09540	COG1739	Uncharacterized protein family UPF0029
CA265_RS09545	COG0813	purine-nucleoside phosphorylase activity
CA265_RS09550	COG2205	protein histidine kinase activity
CA265_RS09560	COG2017	converts alpha-aldose to the beta-anomer
CA265_RS09570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA265_RS09580	COG2885	chlorophyll binding
CA265_RS09585	COG0513	Belongs to the DEAD box helicase family
CA265_RS09590	COG1619	proteins homologs of microcin C7 resistance protein MccF
CA265_RS09600	COG4115	mRNA cleavage
CA265_RS09620	COG0277	FAD linked oxidase domain protein
CA265_RS09630	COG1960	acyl-CoA dehydrogenase activity
CA265_RS09650	COG0019	diaminopimelate decarboxylase activity
CA265_RS09655	COG0527	aspartate kinase activity
CA265_RS09660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CA265_RS09680	COG1858	cytochrome C peroxidase
CA265_RS09700	COG1999	signal sequence binding
CA265_RS09715	COG2326	polyphosphate kinase activity
CA265_RS09750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA265_RS09755	COG0156	8-amino-7-oxononanoate synthase activity
CA265_RS09760	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CA265_RS09770	COG0584	glycerophosphoryl diester phosphodiesterase
CA265_RS09790	COG1629	transport
CA265_RS09805	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CA265_RS09810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CA265_RS09815	COG0363	glucosamine-6-phosphate deaminase activity
CA265_RS09830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CA265_RS09840	COG1666	GTP binding
CA265_RS09860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CA265_RS09865	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CA265_RS09870	COG2080	2 iron, 2 sulfur cluster binding
CA265_RS09875	COG3132	Protein of unknown function, DUF480
CA265_RS09880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CA265_RS09890	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CA265_RS09910	COG0300	oxidoreductase activity
CA265_RS09920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CA265_RS09940	COG3537	Alpha-1,2-mannosidase
CA265_RS09945	COG0482	sulfurtransferase activity
CA265_RS09955	COG0745	RESPONSE REGULATOR receiver
CA265_RS09960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CA265_RS09975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA265_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS09990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CA265_RS09995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CA265_RS10000	COG2146	nitrite reductase [NAD(P)H] activity
CA265_RS10000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CA265_RS10010	COG2223	nitrite transmembrane transporter activity
CA265_RS10015	COG0243	molybdopterin cofactor binding
CA265_RS10030	COG0746	molybdenum cofactor guanylyltransferase activity
CA265_RS10055	COG4771	TonB-dependent receptor
CA265_RS10060	COG3279	Response regulator of the LytR AlgR family
CA265_RS10075	COG0280	phosphate acetyltransferase
CA265_RS10075	COG0857	belongs to the CobB CobQ family
CA265_RS10080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CA265_RS10095	COG1914	H( )-stimulated, divalent metal cation uptake system
CA265_RS10100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CA265_RS10105	COG1984	allophanate hydrolase subunit 2
CA265_RS10110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CA265_RS10130	COG0025	NhaP-type Na H and K H
CA265_RS10145	COG0745	RESPONSE REGULATOR receiver
CA265_RS10155	COG1045	serine acetyltransferase
CA265_RS10180	COG3239	Fatty acid desaturase
CA265_RS10200	COG0647	UMP catabolic process
CA265_RS10215	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CA265_RS10240	COG0702	epimerase
CA265_RS10245	COG1629	transport
CA265_RS10250	COG0702	epimerase
CA265_RS10255	COG4771	TonB-dependent receptor
CA265_RS10265	COG0745	RESPONSE REGULATOR receiver
CA265_RS10265	COG3292	Two component regulator propeller
CA265_RS10265	COG2205	protein histidine kinase activity
CA265_RS10295	COG0702	epimerase
CA265_RS10300	COG1629	transport
CA265_RS10325	COG1629	transport
CA265_RS10335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA265_RS10340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS10350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS10370	COG4771	TonB-dependent receptor
CA265_RS10390	COG1278	Cold shock
CA265_RS10395	COG3279	Response regulator of the LytR AlgR family
CA265_RS10420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CA265_RS10425	COG3250	beta-galactosidase activity
CA265_RS10445	COG0628	permease
CA265_RS10450	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CA265_RS10465	COG0018	arginyl-trna synthetase
CA265_RS10470	COG2235	arginine
CA265_RS10490	COG2824	Alkylphosphonate utilization operon protein PhnA
CA265_RS10500	COG1166	arginine decarboxylase activity
CA265_RS10520	COG4172	Belongs to the ABC transporter superfamily
CA265_RS10530	COG0557	exoribonuclease II activity
CA265_RS10545	COG2801	Transposase and inactivated derivatives
CA265_RS10545	COG3415	Transposase
CA265_RS10550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CA265_RS10555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CA265_RS10595	COG1301	dicarboxylic acid transport
CA265_RS10600	COG1595	DNA-templated transcription, initiation
CA265_RS10625	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CA265_RS10630	COG0492	ferredoxin-NADP+ reductase activity
CA265_RS10640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CA265_RS10670	COG4771	TonB-dependent receptor
CA265_RS10675	COG0517	IMP dehydrogenase activity
CA265_RS10675	COG0516	GMP reductase activity
CA265_RS10695	COG3123	guanosine phosphorylase activity
CA265_RS10705	COG0612	Peptidase, M16
CA265_RS10725	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CA265_RS10740	COG3279	Response regulator of the LytR AlgR family
CA265_RS10745	COG3275	phosphorelay sensor kinase activity
CA265_RS10765	COG0697	spore germination
CA265_RS10785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CA265_RS10790	COG2264	protein methyltransferase activity
CA265_RS10795	COG0149	triose-phosphate isomerase activity
CA265_RS10805	COG0254	rRNA binding
CA265_RS10815	COG0346	lactoylglutathione lyase activity
CA265_RS10825	COG0822	iron-sulfur transferase activity
CA265_RS10830	COG0316	Belongs to the HesB IscA family
CA265_RS10835	COG1022	Amp-dependent synthetase and ligase
CA265_RS10855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CA265_RS10890	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CA265_RS10920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CA265_RS10925	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CA265_RS10930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CA265_RS10935	COG2363	Small membrane protein
CA265_RS10950	COG1214	PFAM Peptidase M22, glycoprotease
CA265_RS10960	COG0594	ribonuclease P activity
CA265_RS10965	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CA265_RS10975	COG3279	Response regulator of the LytR AlgR family
CA265_RS10980	COG3275	phosphorelay sensor kinase activity
CA265_RS11000	COG1970	mechanosensitive ion channel activity
CA265_RS11005	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CA265_RS11030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CA265_RS11035	COG1078	dGTPase activity
CA265_RS11085	COG4771	TonB-dependent receptor
CA265_RS11115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CA265_RS11135	COG3119	arylsulfatase activity
CA265_RS11175	COG0702	epimerase
CA265_RS11180	COG4771	TonB-dependent receptor
CA265_RS11195	COG0702	epimerase
CA265_RS11205	COG3292	Two component regulator propeller
CA265_RS11205	COG0745	RESPONSE REGULATOR receiver
CA265_RS11205	COG2205	protein histidine kinase activity
CA265_RS11205	COG3292	Two component regulator propeller
CA265_RS11205	COG2205	protein histidine kinase activity
CA265_RS11205	COG0745	RESPONSE REGULATOR receiver
CA265_RS11215	COG3119	arylsulfatase activity
CA265_RS11220	COG3119	arylsulfatase activity
CA265_RS11255	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CA265_RS11280	COG0702	epimerase
CA265_RS11285	COG1629	transport
CA265_RS11300	COG1940	carbohydrate kinase activity
CA265_RS11305	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CA265_RS11330	COG5434	Belongs to the glycosyl hydrolase 28 family
CA265_RS11335	COG5434	Belongs to the glycosyl hydrolase 28 family
CA265_RS11350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CA265_RS11385	COG0702	epimerase
CA265_RS11390	COG1629	transport
CA265_RS11400	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA265_RS11405	COG1917	Cupin 2, conserved barrel domain protein
CA265_RS11405	COG2169	Transcriptional regulator
CA265_RS11445	COG0561	phosphatase activity
CA265_RS11450	COG4771	TonB-dependent receptor
CA265_RS11530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CA265_RS11540	COG0443	Heat shock 70 kDa protein
CA265_RS11555	COG0702	epimerase
CA265_RS11560	COG1629	transport
CA265_RS11595	COG1011	Hydrolase
CA265_RS11615	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CA265_RS11635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CA265_RS11640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CA265_RS11645	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CA265_RS11655	COG3279	Response regulator of the LytR AlgR family
CA265_RS11660	COG2205	protein histidine kinase activity
CA265_RS11660	COG2202	Pas domain
CA265_RS11675	COG0436	Aminotransferase
CA265_RS11685	COG0582	viral genome integration into host DNA
CA265_RS11695	COG2003	Belongs to the UPF0758 family
CA265_RS11715	COG1629	transport
CA265_RS11725	COG3119	arylsulfatase activity
CA265_RS11755	COG0741	lytic transglycosylase activity
CA265_RS11755	COG1196	nuclear chromosome segregation
CA265_RS11755	COG0739	heme binding
CA265_RS11815	COG3118	belongs to the thioredoxin family
CA265_RS11820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CA265_RS11825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS11835	COG4771	TonB-dependent receptor
CA265_RS11885	COG4771	TonB-dependent receptor
CA265_RS11895	COG1595	DNA-templated transcription, initiation
CA265_RS11965	COG0587	DNA-directed DNA polymerase activity
CA265_RS11970	COG0275	rRNA processing
CA265_RS11980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CA265_RS11990	COG0745	RESPONSE REGULATOR receiver
CA265_RS11995	COG1595	DNA-templated transcription, initiation
CA265_RS12020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CA265_RS12040	COG0673	inositol 2-dehydrogenase activity
CA265_RS12065	COG0702	epimerase
CA265_RS12070	COG4771	TonB-dependent receptor
CA265_RS12105	COG4206	TonB-dependent receptor
CA265_RS12105	COG1629	transport
CA265_RS12125	COG0702	epimerase
CA265_RS12130	COG1629	transport
CA265_RS12145	COG2755	lipolytic protein G-D-S-L family
CA265_RS12145	COG0657	acetylesterase activity
CA265_RS12150	COG0657	acetylesterase activity
CA265_RS12155	COG3119	arylsulfatase activity
CA265_RS12165	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CA265_RS12180	COG3325	Belongs to the glycosyl hydrolase 18 family
CA265_RS12180	COG3469	chitinase activity
CA265_RS12190	COG4206	TonB-dependent receptor
CA265_RS12190	COG1629	transport
CA265_RS12240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CA265_RS12250	COG4948	Mandelate Racemase Muconate Lactonizing
CA265_RS12255	COG1082	Xylose isomerase domain protein TIM barrel
CA265_RS12270	COG1595	DNA-templated transcription, initiation
CA265_RS12285	COG3685	Protein conserved in bacteria
CA265_RS12290	COG3279	Response regulator of the LytR AlgR family
CA265_RS12295	COG0745	RESPONSE REGULATOR receiver
CA265_RS12295	COG2972	Histidine kinase
CA265_RS12330	COG0745	RESPONSE REGULATOR receiver
CA265_RS12335	COG2205	protein histidine kinase activity
CA265_RS12335	COG2202	Pas domain
CA265_RS12345	COG2205	protein histidine kinase activity
CA265_RS12345	COG3292	Two component regulator propeller
CA265_RS12345	COG0745	RESPONSE REGULATOR receiver
CA265_RS12345	COG3292	Two component regulator propeller
CA265_RS12345	COG0745	RESPONSE REGULATOR receiver
CA265_RS12345	COG2205	protein histidine kinase activity
CA265_RS12380	COG0753	catalase activity
CA265_RS12425	COG1629	transport
CA265_RS12425	COG4206	TonB-dependent receptor
CA265_RS12455	COG0702	epimerase
CA265_RS12460	COG4771	TonB-dependent receptor
CA265_RS12480	COG0673	inositol 2-dehydrogenase activity
CA265_RS12525	COG1629	transport
CA265_RS12525	COG4206	TonB-dependent receptor
CA265_RS12535	COG1595	DNA-templated transcription, initiation
CA265_RS12595	COG1595	DNA-templated transcription, initiation
CA265_RS12605	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CA265_RS12615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CA265_RS12620	COG0303	'Molybdopterin
CA265_RS12640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CA265_RS12650	COG0315	cyclic pyranopterin monophosphate synthase activity
CA265_RS12650	COG0521	Mo-molybdopterin cofactor biosynthetic process
CA265_RS12665	COG1278	Cold shock
CA265_RS12685	COG1132	(ABC) transporter
CA265_RS12690	COG1132	(ABC) transporter
CA265_RS12700	COG2996	Protein conserved in bacteria
CA265_RS12710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CA265_RS12735	COG1595	DNA-templated transcription, initiation
CA265_RS12755	COG1064	alcohol dehydrogenase
CA265_RS12760	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CA265_RS12770	COG3408	Glycogen debranching enzyme
CA265_RS12775	COG0542	response to heat
CA265_RS12795	COG2223	nitrite transmembrane transporter activity
CA265_RS12835	COG0726	polysaccharide deacetylase
CA265_RS12840	COG0726	polysaccharide deacetylase
CA265_RS12840	COG1649	PFAM Uncharacterised BCR, COG1649
CA265_RS12860	COG0778	Nitroreductase
CA265_RS12875	COG0488	(ABC) transporter
CA265_RS12915	COG1331	Highly conserved protein containing a thioredoxin domain
CA265_RS12920	COG4948	Mandelate Racemase Muconate Lactonizing
CA265_RS12925	COG3757	hydrolase, family 25
CA265_RS12930	COG2814	Major facilitator Superfamily
CA265_RS12970	COG1733	regulation of RNA biosynthetic process
CA265_RS12980	COG0210	DNA helicase
CA265_RS12990	COG1196	nuclear chromosome segregation
CA265_RS13005	COG2234	aminopeptidase activity
CA265_RS13020	COG0357	Ribosomal RNA small subunit methyltransferase G
CA265_RS13030	COG0343	queuine tRNA-ribosyltransferase activity
CA265_RS13060	COG1741	Belongs to the pirin family
CA265_RS13070	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CA265_RS13090	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CA265_RS13095	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CA265_RS13100	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CA265_RS13105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CA265_RS13110	COG1252	NADH dehydrogenase
CA265_RS13135	COG0191	fructose-bisphosphate aldolase activity
CA265_RS13140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CA265_RS13160	COG1271	oxidase subunit
CA265_RS13180	COG1104	cysteine desulfurase activity
CA265_RS13185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CA265_RS13195	COG2226	methyltransferase
CA265_RS13210	COG4636	protein conserved in cyanobacteria
CA265_RS13215	COG4636	protein conserved in cyanobacteria
CA265_RS13220	COG4636	protein conserved in cyanobacteria
CA265_RS13230	COG0237	dephospho-CoA kinase activity
CA265_RS13240	COG1862	Preprotein translocase
CA265_RS13250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CA265_RS13260	COG1132	(ABC) transporter
CA265_RS13275	COG0012	GTP binding
CA265_RS13285	COG2239	Acts as a magnesium transporter
CA265_RS13350	COG3507	Belongs to the glycosyl hydrolase 43 family
CA265_RS13360	COG0702	epimerase
CA265_RS13365	COG1629	transport
CA265_RS13370	COG0702	epimerase
CA265_RS13375	COG1629	transport
CA265_RS13410	COG3292	Two component regulator propeller
CA265_RS13410	COG2205	protein histidine kinase activity
CA265_RS13410	COG0745	RESPONSE REGULATOR receiver
CA265_RS13420	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CA265_RS13435	COG3064	Membrane
CA265_RS13475	COG0702	epimerase
CA265_RS13480	COG4771	TonB-dependent receptor
CA265_RS13490	COG0583	DNA-binding transcription factor activity
CA265_RS13495	COG2226	methyltransferase
CA265_RS13515	COG4771	TonB-dependent receptor
CA265_RS13545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CA265_RS13560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CA265_RS13575	COG0456	acetyltransferase
CA265_RS13610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CA265_RS13625	COG0662	Cupin 2, conserved barrel domain protein
CA265_RS13625	COG2207	Transcriptional regulator
CA265_RS13630	COG1629	transport
CA265_RS13655	COG3386	PFAM SMP-30 Gluconolaconase
CA265_RS13660	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS13665	COG4948	Mandelate Racemase Muconate Lactonizing
CA265_RS13670	COG3250	beta-galactosidase activity
CA265_RS13675	COG3250	beta-galactosidase activity
CA265_RS13680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CA265_RS13690	COG4771	TonB-dependent receptor
CA265_RS13725	COG2353	YceI-like domain
CA265_RS13735	COG1522	sequence-specific DNA binding
CA265_RS13740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CA265_RS13750	COG4232	protein-disulfide reductase activity
CA265_RS13755	COG4771	TonB-dependent receptor
CA265_RS13770	COG3250	beta-galactosidase activity
CA265_RS13775	COG3664	PFAM glycoside hydrolase family 39
CA265_RS13790	COG3254	rhamnose metabolic process
CA265_RS13805	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CA265_RS13815	COG2755	lipolytic protein G-D-S-L family
CA265_RS13820	COG2755	lipolytic protein G-D-S-L family
CA265_RS13825	COG3401	FG-GAP repeat protein
CA265_RS13850	COG1082	Xylose isomerase domain protein TIM barrel
CA265_RS13870	COG2755	lipolytic protein G-D-S-L family
CA265_RS13875	COG0604	alcohol dehydrogenase
CA265_RS13875	COG3321	synthase
CA265_RS13880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA265_RS13880	COG3321	synthase
CA265_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS13880	COG0300	oxidoreductase activity
CA265_RS13880	COG0318	PFAM AMP-dependent synthetase and ligase
CA265_RS13885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA265_RS13890	COG2267	carboxylic ester hydrolase activity
CA265_RS13925	COG0596	Alpha beta hydrolase
CA265_RS13935	COG3279	Response regulator of the LytR AlgR family
CA265_RS13945	COG2234	aminopeptidase activity
CA265_RS13950	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CA265_RS13955	COG1752	Esterase of the alpha-beta hydrolase superfamily
CA265_RS13975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA265_RS14000	COG4912	Dna alkylation repair
CA265_RS14005	COG0167	dihydroorotate dehydrogenase activity
CA265_RS14015	COG1959	2 iron, 2 sulfur cluster binding
CA265_RS14020	COG0488	(ABC) transporter
CA265_RS14035	COG0673	inositol 2-dehydrogenase activity
CA265_RS14040	COG1477	protein flavinylation
CA265_RS14045	COG3622	Belongs to the hyi family
CA265_RS14055	COG1607	acyl-coa hydrolase
CA265_RS14095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CA265_RS14105	COG1205	dead DEAH box helicase
CA265_RS14105	COG1111	helicase
CA265_RS14110	COG1484	DNA-dependent DNA replication
CA265_RS14120	COG1401	restriction endodeoxyribonuclease activity
CA265_RS14135	COG4585	Histidine kinase
CA265_RS14170	COG2003	Belongs to the UPF0758 family
CA265_RS14205	COG0702	epimerase
CA265_RS14210	COG4771	TonB-dependent receptor
CA265_RS14215	COG2205	protein histidine kinase activity
CA265_RS14215	COG3292	Two component regulator propeller
CA265_RS14215	COG0745	RESPONSE REGULATOR receiver
CA265_RS14235	COG3119	arylsulfatase activity
CA265_RS14240	COG2755	lipolytic protein G-D-S-L family
CA265_RS14240	COG0657	acetylesterase activity
CA265_RS14265	COG3415	Transposase
CA265_RS14265	COG2801	Transposase and inactivated derivatives
CA265_RS14270	COG0673	inositol 2-dehydrogenase activity
CA265_RS14280	COG0673	inositol 2-dehydrogenase activity
CA265_RS14290	COG0525	valine-tRNA ligase activity
CA265_RS14310	COG2217	Heavy metal translocating P-type atpase
CA265_RS14315	COG3590	peptidase
CA265_RS14335	COG0667	Aldo Keto reductase
CA265_RS14340	COG0628	permease
CA265_RS14355	COG3956	TIGRFAM MazG family protein
CA265_RS14360	COG3012	SEC-C Motif Domain Protein
CA265_RS14365	COG0101	tRNA pseudouridine synthase activity
CA265_RS14380	COG4591	ABC-type transport system involved in lipoprotein release permease component
CA265_RS14385	COG3876	Protein conserved in bacteria
CA265_RS14395	COG5002	protein histidine kinase activity
CA265_RS14405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CA265_RS14415	COG0564	pseudouridine synthase activity
CA265_RS14425	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CA265_RS14435	COG2388	GCN5-related N-acetyl-transferase
CA265_RS14445	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS14465	COG1960	acyl-CoA dehydrogenase activity
CA265_RS14470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CA265_RS14475	COG0386	Belongs to the glutathione peroxidase family
CA265_RS14485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CA265_RS14495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CA265_RS14515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CA265_RS14525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CA265_RS14540	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CA265_RS14555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CA265_RS14570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CA265_RS14575	COG1528	Iron-storage protein
CA265_RS14580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CA265_RS14605	COG2183	response to ionizing radiation
CA265_RS14605	COG0539	negative regulation of cytoplasmic translation
CA265_RS14610	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CA265_RS14630	COG2207	Transcriptional regulator
CA265_RS14635	COG1012	belongs to the aldehyde dehydrogenase family
CA265_RS14650	COG3011	Protein conserved in bacteria
CA265_RS14655	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CA265_RS14660	COG0540	Belongs to the ATCase OTCase family
CA265_RS14685	COG2312	Erythromycin esterase
CA265_RS14700	COG4206	TonB-dependent receptor
CA265_RS14700	COG1629	transport
CA265_RS14720	COG1629	transport
CA265_RS14740	COG0811	peptide transport
CA265_RS14745	COG0848	biopolymer transport protein
CA265_RS14755	COG0285	dihydrofolate synthase activity
CA265_RS14780	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CA265_RS14780	COG1703	isobutyryl-CoA mutase activity
CA265_RS14780	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CA265_RS14785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CA265_RS14855	COG0497	DNA recombination
CA265_RS14890	COG0542	response to heat
CA265_RS14900	COG4771	TonB-dependent receptor
CA265_RS14910	COG0488	(ABC) transporter
CA265_RS14940	COG4807	Protein conserved in bacteria
CA265_RS14945	COG0513	Belongs to the DEAD box helicase family
CA265_RS14975	COG0004	ammonium transporteR
CA265_RS14980	COG1242	4 iron, 4 sulfur cluster binding
CA265_RS14990	COG0531	amino acid
CA265_RS14995	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CA265_RS15000	COG0531	amino acid
CA265_RS15010	COG2095	MarC family integral membrane protein
CA265_RS15015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CA265_RS15025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CA265_RS15025	COG0519	Catalyzes the synthesis of GMP from XMP
CA265_RS15055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CA265_RS15060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CA265_RS15065	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CA265_RS15080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CA265_RS15090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CA265_RS15105	COG1610	YqeY-like protein
CA265_RS15120	COG2226	methyltransferase
CA265_RS15125	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CA265_RS15130	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CA265_RS15140	COG2814	Major facilitator Superfamily
CA265_RS15145	COG0531	amino acid
CA265_RS15155	COG3158	transport of potassium into the cell
CA265_RS15165	COG0179	Fumarylacetoacetate (FAA) hydrolase
CA265_RS15175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CA265_RS15180	COG3959	Transketolase, thiamine diphosphate binding domain
CA265_RS15185	COG3958	Transketolase
CA265_RS15190	COG1595	DNA-templated transcription, initiation
CA265_RS15205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CA265_RS15210	COG0745	RESPONSE REGULATOR receiver
CA265_RS15215	COG5002	protein histidine kinase activity
CA265_RS15230	COG0564	pseudouridine synthase activity
CA265_RS15235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CA265_RS15240	COG0505	Belongs to the CarA family
CA265_RS15265	COG1309	transcriptional regulator
CA265_RS15275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CA265_RS15280	COG0156	8-amino-7-oxononanoate synthase activity
CA265_RS15290	COG1054	Belongs to the UPF0176 family
CA265_RS15300	COG4771	TonB-dependent receptor
CA265_RS15305	COG0702	epimerase
CA265_RS15320	COG1472	Belongs to the glycosyl hydrolase 3 family
CA265_RS15330	COG0217	transcriptional regulatory protein
CA265_RS15335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA265_RS15350	COG0673	inositol 2-dehydrogenase activity
CA265_RS15360	COG4654	Cytochrome c, class I
CA265_RS15365	COG0673	inositol 2-dehydrogenase activity
CA265_RS15375	COG2211	Major facilitator Superfamily
CA265_RS15380	COG1082	Xylose isomerase domain protein TIM barrel
CA265_RS15395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CA265_RS15415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CA265_RS15425	COG0148	phosphopyruvate hydratase activity
CA265_RS15435	COG2860	membrane
CA265_RS15445	COG3034	peptidoglycan biosynthetic process
CA265_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS15495	COG3118	belongs to the thioredoxin family
CA265_RS15505	COG0702	epimerase
CA265_RS15510	COG4771	TonB-dependent receptor
CA265_RS15520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CA265_RS15520	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CA265_RS15530	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CA265_RS15530	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CA265_RS15535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CA265_RS15540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CA265_RS15555	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CA265_RS15560	COG1301	dicarboxylic acid transport
CA265_RS15565	COG1446	asparaginase
CA265_RS15575	COG1132	(ABC) transporter
CA265_RS15610	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CA265_RS15635	COG4206	TonB-dependent receptor
CA265_RS15635	COG1629	transport
CA265_RS15640	COG1940	carbohydrate kinase activity
CA265_RS15660	COG1629	transport
CA265_RS15665	COG0681	Belongs to the peptidase S26 family
CA265_RS15670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CA265_RS15680	COG1475	DNA binding
CA265_RS15685	COG1192	Involved in chromosome partitioning
CA265_RS15700	COG5002	protein histidine kinase activity
CA265_RS15710	COG1082	Xylose isomerase domain protein TIM barrel
CA265_RS15730	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CA265_RS15735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CA265_RS15740	COG0563	adenylate kinase activity
CA265_RS15770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CA265_RS15775	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CA265_RS15780	COG2267	carboxylic ester hydrolase activity
CA265_RS15805	COG0028	Belongs to the TPP enzyme family
CA265_RS15810	COG0440	acetolactate synthase activity
CA265_RS15825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CA265_RS15830	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CA265_RS15835	COG2329	Antibiotic biosynthesis monooxygenase
CA265_RS15840	COG0066	3-isopropylmalate dehydratase activity
CA265_RS15845	COG1119	ATPase activity
CA265_RS15850	COG0473	3-isopropylmalate dehydrogenase activity
CA265_RS15855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CA265_RS15860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CA265_RS15865	COG1917	Cupin 2, conserved barrel domain protein
CA265_RS15915	COG1981	membrane
CA265_RS15930	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CA265_RS15940	COG0745	RESPONSE REGULATOR receiver
CA265_RS15945	COG5002	protein histidine kinase activity
CA265_RS15950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CA265_RS15955	COG0113	porphobilinogen synthase activity
CA265_RS15960	COG0181	hydroxymethylbilane synthase activity
CA265_RS15965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CA265_RS15975	COG0596	Alpha beta hydrolase
CA265_RS15985	COG0668	transmembrane transport
CA265_RS15990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CA265_RS16010	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS16015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CA265_RS16020	COG1127	ABC transporter
CA265_RS16035	COG0116	Belongs to the methyltransferase superfamily
CA265_RS16035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CA265_RS16060	COG2936	dipeptidyl-peptidase activity
CA265_RS16100	COG0531	amino acid
CA265_RS16115	COG0513	Belongs to the DEAD box helicase family
CA265_RS16120	COG0495	leucyl-tRNA aminoacylation
CA265_RS16130	COG2177	Part of the ABC transporter FtsEX involved in
CA265_RS16150	COG1968	undecaprenyl-diphosphatase activity
CA265_RS16155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CA265_RS16160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CA265_RS16165	COG0196	riboflavin kinase activity
CA265_RS16170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CA265_RS16170	COG4651	solute:proton antiporter activity
CA265_RS16180	COG0432	Pfam Uncharacterised protein family UPF0047
CA265_RS16185	COG1295	ribonuclease BN
CA265_RS16200	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CA265_RS16210	COG2169	Transcriptional regulator
CA265_RS16220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CA265_RS16260	COG0561	phosphatase activity
CA265_RS16265	COG4771	TonB-dependent receptor
CA265_RS16290	COG4771	TonB-dependent receptor
CA265_RS16300	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA265_RS16310	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CA265_RS16315	COG0612	Peptidase, M16
CA265_RS16320	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CA265_RS16325	COG3237	CsbD-like
CA265_RS16330	COG4771	TonB-dependent receptor
CA265_RS16340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CA265_RS16345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CA265_RS16350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CA265_RS16360	COG0552	protein localization to endoplasmic reticulum
CA265_RS16365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CA265_RS16375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CA265_RS16390	COG0726	polysaccharide deacetylase
CA265_RS16400	COG1049	propionate catabolic process, 2-methylcitrate cycle
CA265_RS16425	COG2723	6-phospho-beta-galactosidase activity
CA265_RS16465	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CA265_RS16470	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CA265_RS16485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CA265_RS16505	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CA265_RS16510	COG1663	tetraacyldisaccharide 4'-kinase activity
CA265_RS16525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA265_RS16545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CA265_RS16550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA265_RS16595	COG2972	Histidine kinase
CA265_RS16600	COG3279	Response regulator of the LytR AlgR family
CA265_RS16605	COG1012	belongs to the aldehyde dehydrogenase family
CA265_RS16610	COG3119	arylsulfatase activity
CA265_RS16620	COG0288	reversible hydration of carbon dioxide
CA265_RS16625	COG0659	secondary active sulfate transmembrane transporter activity
CA265_RS16635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CA265_RS16640	COG2814	Major facilitator Superfamily
CA265_RS16655	COG1363	Peptidase, m42
CA265_RS16670	COG0708	Exodeoxyribonuclease III
CA265_RS16675	COG1595	DNA-templated transcription, initiation
CA265_RS16705	COG1506	peptidase
CA265_RS16720	COG0433	COG0433 Predicted ATPase
CA265_RS16745	COG0443	Heat shock 70 kDa protein
CA265_RS16785	COG0203	ribosomal protein L17
CA265_RS16790	COG0202	RNA polymerase activity
CA265_RS16795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CA265_RS16800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CA265_RS16805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CA265_RS16810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CA265_RS16815	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CA265_RS16830	COG0200	Binds to the 23S rRNA
CA265_RS16835	COG1841	ribosomal large subunit assembly
CA265_RS16840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CA265_RS16845	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CA265_RS16850	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CA265_RS16855	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CA265_RS16860	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CA265_RS16865	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CA265_RS16870	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CA265_RS16875	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CA265_RS16880	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CA265_RS16885	COG0255	Belongs to the universal ribosomal protein uL29 family
CA265_RS16890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CA265_RS16895	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CA265_RS16900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CA265_RS16905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CA265_RS16910	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CA265_RS16915	COG0089	rRNA binding
CA265_RS16920	COG0088	Forms part of the polypeptide exit tunnel
CA265_RS16925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CA265_RS16935	COG0730	response to heat
CA265_RS17005	COG0051	transcription antitermination factor activity, RNA binding
CA265_RS17010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CA265_RS17015	COG0049	tRNA binding
CA265_RS17020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CA265_RS17050	COG0702	epimerase
CA265_RS17055	COG1629	transport
CA265_RS17060	COG0529	Catalyzes the synthesis of activated sulfate
CA265_RS17065	COG1218	3'(2'),5'-bisphosphate nucleotidase
CA265_RS17075	COG2059	Chromate
CA265_RS17090	COG4628	conserved protein (DUF2132)
CA265_RS17095	COG2226	methyltransferase
CA265_RS17115	COG1393	Belongs to the ArsC family
CA265_RS17120	COG3275	phosphorelay sensor kinase activity
CA265_RS17125	COG3279	Response regulator of the LytR AlgR family
CA265_RS17130	COG2373	Large extracellular alpha-helical protein
CA265_RS17135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CA265_RS17145	COG0579	oxidoreductase
CA265_RS17160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CA265_RS17180	COG0277	FAD linked oxidase domain protein
CA265_RS17190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CA265_RS17195	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CA265_RS17200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CA265_RS17220	COG0778	Nitroreductase
CA265_RS17250	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CA265_RS17255	COG5520	Belongs to the glycosyl hydrolase 30 family
CA265_RS17260	COG0702	epimerase
CA265_RS17265	COG1629	transport
CA265_RS17325	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CA265_RS17395	COG0531	amino acid
CA265_RS17435	COG1381	Involved in DNA repair and RecF pathway recombination
CA265_RS17465	COG0300	oxidoreductase activity
CA265_RS17470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA265_RS17485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CA265_RS17490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CA265_RS17495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CA265_RS17530	COG0567	Dehydrogenase, E1 component
CA265_RS17535	COG0415	Belongs to the DNA photolyase family
CA265_RS17540	COG1090	epimerase
CA265_RS17545	COG0415	Belongs to the DNA photolyase family
CA265_RS17570	COG0545	Peptidyl-prolyl cis-trans isomerase
CA265_RS17575	COG1960	acyl-CoA dehydrogenase activity
CA265_RS17585	COG0183	Belongs to the thiolase family
CA265_RS17590	COG1024	Enoyl-CoA hydratase
CA265_RS17590	COG1250	3-hydroxyacyl-CoA dehydrogenase
CA265_RS17605	COG2885	chlorophyll binding
CA265_RS17620	COG0405	Gamma-glutamyltransferase
CA265_RS17625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS17640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA265_RS17645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA265_RS17650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CA265_RS17665	COG0745	RESPONSE REGULATOR receiver
CA265_RS17675	COG0326	Molecular chaperone. Has ATPase activity
CA265_RS17690	COG3279	Response regulator of the LytR AlgR family
CA265_RS17695	COG2972	Histidine kinase
CA265_RS17730	COG1360	Flagellar Motor Protein
CA265_RS17765	COG4771	TonB-dependent receptor
CA265_RS17775	COG1595	DNA-templated transcription, initiation
CA265_RS17780	COG2322	membrane
CA265_RS17795	COG1845	cytochrome c oxidase, subunit III
CA265_RS17800	COG1845	cytochrome c oxidase, subunit III
CA265_RS17805	COG0109	protoheme IX farnesyltransferase activity
CA265_RS17815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CA265_RS17820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CA265_RS17845	COG0437	4 iron, 4 sulfur cluster binding
CA265_RS17880	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA265_RS17885	COG3682	Transcriptional regulator
CA265_RS17945	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CA265_RS17965	COG1473	amidohydrolase
CA265_RS18010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA265_RS18015	COG1215	transferase activity, transferring glycosyl groups
CA265_RS18025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CA265_RS18050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CA265_RS18055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CA265_RS18060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CA265_RS18065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CA265_RS18070	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CA265_RS18075	COG0356	it plays a direct role in the translocation of protons across the membrane
CA265_RS18110	COG0322	excinuclease ABC activity
CA265_RS18155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CA265_RS18175	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CA265_RS18195	COG0110	maltose O-acetyltransferase activity
CA265_RS18205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA265_RS18225	COG0745	RESPONSE REGULATOR receiver
CA265_RS18275	COG1694	Mazg nucleotide pyrophosphohydrolase
CA265_RS18285	COG1490	D-aminoacyl-tRNA deacylase activity
CA265_RS18305	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CA265_RS18315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CA265_RS18320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CA265_RS18345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CA265_RS18350	COG0416	fatty acid biosynthetic process
CA265_RS18355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CA265_RS18360	COG0511	ligase activity, forming carbon-carbon bonds
CA265_RS18365	COG0439	Biotin carboxylase
CA265_RS18375	COG0805	protein transport
CA265_RS18380	COG0698	ribose 5-phosphate isomerase
CA265_RS18385	COG2234	aminopeptidase activity
CA265_RS18400	COG1139	Iron-sulfur cluster binding protein
CA265_RS18405	COG0022	dehydrogenase e1 component
CA265_RS18410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CA265_RS18430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CA265_RS18435	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CA265_RS18440	COG1621	beta-fructofuranosidase activity
CA265_RS18450	COG0330	HflC and HflK could
CA265_RS18455	COG3541	Predicted nucleotidyltransferase
CA265_RS18465	COG1690	Belongs to the RtcB family
CA265_RS18470	COG0436	Aminotransferase
CA265_RS18485	COG0165	Argininosuccinate lyase
CA265_RS18510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CA265_RS18530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CA265_RS18540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CA265_RS18545	COG0137	argininosuccinate synthase activity
CA265_RS18575	COG0702	epimerase
CA265_RS18580	COG4771	TonB-dependent receptor
CA265_RS18610	COG2234	aminopeptidase activity
CA265_RS18610	COG4935	Belongs to the peptidase S8 family
CA265_RS18625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA265_RS18635	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CA265_RS18660	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CA265_RS18685	COG0702	epimerase
CA265_RS18695	COG3848	Pyruvate phosphate dikinase
CA265_RS18695	COG0574	Belongs to the PEP-utilizing enzyme family
CA265_RS18710	COG1629	transport
CA265_RS18720	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CA265_RS18725	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS18740	COG0469	pyruvate kinase activity
CA265_RS18750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA265_RS18755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CA265_RS18760	COG0571	ribonuclease III activity
CA265_RS18780	COG1561	YicC-like family, N-terminal region
CA265_RS18785	COG0194	GDP metabolic process
CA265_RS18795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CA265_RS18800	COG1472	Belongs to the glycosyl hydrolase 3 family
CA265_RS18815	COG0084	hydrolase, TatD family'
CA265_RS18820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CA265_RS18825	COG2852	Protein conserved in bacteria
CA265_RS18830	COG1074	ATP-dependent DNA helicase activity
CA265_RS18845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CA265_RS18860	COG0022	dehydrogenase e1 component
CA265_RS18860	COG0508	dehydrogenase complex catalyzes the overall conversion of
CA265_RS18880	COG2183	response to ionizing radiation
CA265_RS18895	COG3172	ATPase kinase involved in NAD metabolism
CA265_RS18910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CA265_RS18915	COG0052	Belongs to the universal ribosomal protein uS2 family
CA265_RS18920	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CA265_RS18930	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CA265_RS18935	COG0528	UMP kinase activity
CA265_RS18940	COG0233	cytoplasmic translational termination
CA265_RS18945	COG1609	Transcriptional regulator
CA265_RS18950	COG1522	sequence-specific DNA binding
CA265_RS18980	COG0509	glycine decarboxylation via glycine cleavage system
CA265_RS18995	COG0632	four-way junction helicase activity
CA265_RS19005	COG3942	CHAP domain
CA265_RS19005	COG1388	LysM domain
CA265_RS19010	COG0154	amidase activity
CA265_RS19015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CA265_RS19020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CA265_RS19040	COG0756	dUTP diphosphatase activity
CA265_RS19050	COG1254	Belongs to the acylphosphatase family
CA265_RS19060	COG0402	S-adenosylhomocysteine deaminase activity
CA265_RS19085	COG2204	response regulator
CA265_RS19090	COG0784	Response regulator, receiver
CA265_RS19090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA265_RS19090	COG2198	Histidine kinase
CA265_RS19090	COG2205	protein histidine kinase activity
CA265_RS19095	COG2378	regulation of single-species biofilm formation
CA265_RS19105	COG0431	NADPH-dependent FMN reductase
CA265_RS19110	COG1187	pseudouridine synthase activity
CA265_RS19115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CA265_RS19160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CA265_RS19165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CA265_RS19170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CA265_RS19175	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CA265_RS19195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CA265_RS19205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA265_RS19210	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CA265_RS19215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA265_RS19225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA265_RS19255	COG0482	sulfurtransferase activity
CA265_RS19285	COG0673	inositol 2-dehydrogenase activity
CA265_RS19300	COG0579	oxidoreductase
CA265_RS19305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CA265_RS19320	COG4464	protein tyrosine phosphatase activity
CA265_RS19360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CA265_RS19375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CA265_RS19420	COG4895	conserved protein (DUF2196)
CA265_RS19430	COG0556	nucleotide-excision repair
CA265_RS19460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CA265_RS19470	COG1011	Hydrolase
CA265_RS19530	COG1446	asparaginase
CA265_RS19555	COG3590	peptidase
CA265_RS19575	COG0791	NLP P60 protein
CA265_RS19580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CA265_RS19585	COG0508	dehydrogenase complex catalyzes the overall conversion of
CA265_RS19600	COG4297	protein containing double-stranded beta helix domain
CA265_RS19605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CA265_RS19610	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CA265_RS19615	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CA265_RS19650	COG0519	Catalyzes the synthesis of GMP from XMP
CA265_RS19675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA265_RS19680	COG0583	DNA-binding transcription factor activity
CA265_RS19705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA265_RS19710	COG1070	Carbohydrate kinase
CA265_RS19730	COG4591	ABC-type transport system involved in lipoprotein release permease component
CA265_RS19735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CA265_RS19745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CA265_RS19750	COG1809	phosphosulfolactate synthase activity
CA265_RS19780	COG1012	belongs to the aldehyde dehydrogenase family
CA265_RS19810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CA265_RS19815	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CA265_RS19825	COG4771	TonB-dependent receptor
CA265_RS19830	COG0702	epimerase
CA265_RS19840	COG4677	pectinesterase activity
CA265_RS19845	COG2755	lipolytic protein G-D-S-L family
CA265_RS19855	COG2271	Major facilitator Superfamily
CA265_RS19870	COG1904	glucuronate isomerase
CA265_RS19875	COG2721	sulfolactate sulfo-lyase activity
CA265_RS19880	COG0246	Mannitol dehydrogenase
CA265_RS19890	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CA265_RS19910	COG2755	lipolytic protein G-D-S-L family
CA265_RS19925	COG3781	membrane
CA265_RS19975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CA265_RS20000	COG2204	response regulator
CA265_RS20005	COG1024	Enoyl-CoA hydratase
CA265_RS20010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CA265_RS20010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CA265_RS20015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA265_RS20055	COG0352	thiamine-phosphate diphosphorylase activity
CA265_RS20080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CA265_RS20095	COG1054	Belongs to the UPF0176 family
CA265_RS20105	COG4948	Mandelate Racemase Muconate Lactonizing
CA265_RS20135	COG2195	Cleaves the N-terminal amino acid of tripeptides
CA265_RS20165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CA265_RS20170	COG0352	thiamine-phosphate diphosphorylase activity
CA265_RS20175	COG0352	thiamine-phosphate diphosphorylase activity
CA265_RS20180	COG2022	thiamine diphosphate biosynthetic process
CA265_RS20185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CA265_RS20240	COG3422	double-strand break repair
CA265_RS20255	COG4106	trans-aconitate 2-methyltransferase activity
CA265_RS20270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA265_RS20270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA265_RS20275	COG1619	proteins homologs of microcin C7 resistance protein MccF
CA265_RS20295	COG1629	transport
CA265_RS20310	COG4771	TonB-dependent receptor
CA265_RS20320	COG4771	TonB-dependent receptor
CA265_RS20335	COG4771	TonB-dependent receptor
CA265_RS20345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CA265_RS20355	COG1774	PSP1 C-terminal conserved region
CA265_RS20360	COG0470	DNA polymerase III
CA265_RS20370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CA265_RS20380	COG1388	LysM domain
CA265_RS20380	COG3942	CHAP domain
CA265_RS20385	COG1705	Flagellar rod assembly protein muramidase FlgJ
CA265_RS20420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CA265_RS20425	COG0606	chelatase, subunit chli
CA265_RS20435	COG2003	Belongs to the UPF0758 family
CA265_RS20470	COG3285	dna ligase
CA265_RS20470	COG1793	dna ligase
CA265_RS20485	COG0732	type I restriction modification DNA specificity domain
CA265_RS20500	COG0587	DNA-directed DNA polymerase activity
CA265_RS20545	COG0156	8-amino-7-oxononanoate synthase activity
CA265_RS20580	COG1228	amidohydrolase
CA265_RS20590	COG3250	beta-galactosidase activity
CA265_RS20600	COG0657	acetylesterase activity
CA265_RS20600	COG2755	lipolytic protein G-D-S-L family
CA265_RS20630	COG0561	phosphatase activity
CA265_RS20635	COG4771	TonB-dependent receptor
CA265_RS20645	COG1595	DNA-templated transcription, initiation
CA265_RS20775	COG0739	heme binding
CA265_RS20775	COG0741	lytic transglycosylase activity
CA265_RS20775	COG1196	nuclear chromosome segregation
CA265_RS20805	COG0193	aminoacyl-tRNA hydrolase activity
CA265_RS20825	COG0606	chelatase, subunit chli
CA265_RS20850	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CA265_RS20855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CA265_RS20870	COG0612	Peptidase, M16
CA265_RS20875	COG0242	peptide deformylase activity
CA265_RS20885	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CA265_RS20890	COG0489	protein tyrosine kinase activity
CA265_RS20895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CA265_RS20905	COG0688	phosphatidylethanolamine metabolic process
CA265_RS20910	COG0668	transmembrane transport
CA265_RS20915	COG0335	large ribosomal subunit rRNA binding
CA265_RS20940	COG2197	response regulator
CA265_RS20945	COG0336	Belongs to the RNA methyltransferase TrmD family
CA265_RS20955	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CA265_RS20960	COG0228	four-way junction DNA binding
CA265_RS20965	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CA265_RS20970	COG1629	transport
CA265_RS20975	COG0393	Putative heavy-metal-binding
CA265_RS20980	COG0205	6-phosphofructokinase activity
CA265_RS20985	COG4232	protein-disulfide reductase activity
CA265_RS20995	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CA265_RS20995	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CA265_RS21000	COG0799	negative regulation of ribosome biogenesis
CA265_RS21005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA265_RS21010	COG1556	Lactate utilization protein
CA265_RS21025	COG3851	Histidine kinase
CA265_RS21035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CA265_RS21050	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CA265_RS21070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CA265_RS21080	COG3530	Putative quorum-sensing-regulated virulence factor
CA265_RS21085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CA265_RS21095	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CA265_RS21100	COG1607	acyl-coa hydrolase
CA265_RS21105	COG2226	methyltransferase
CA265_RS21125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CA265_RS21140	COG2022	thiamine diphosphate biosynthetic process
CA265_RS21140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA265_RS21155	COG0788	formyltetrahydrofolate deformylase activity
CA265_RS21170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CA265_RS21175	COG1301	dicarboxylic acid transport
CA265_RS21180	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CA265_RS21185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CA265_RS21190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CA265_RS21200	COG0445	tRNA wobble uridine modification
CA265_RS21205	COG0488	(ABC) transporter
CA265_RS21210	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CA265_RS21220	COG1595	DNA-templated transcription, initiation
CA265_RS21230	COG1629	transport
CA265_RS21230	COG4206	TonB-dependent receptor
CA265_RS21275	COG3511	phospholipase C
CA265_RS21285	COG2197	response regulator
CA265_RS21295	COG2207	Transcriptional regulator
CA265_RS21300	COG4771	TonB-dependent receptor
CA265_RS21325	COG5297	Belongs to the glycosyl hydrolase family 6
CA265_RS21325	COG3250	beta-galactosidase activity
CA265_RS21330	COG1309	transcriptional regulator
CA265_RS21345	COG2814	Major facilitator Superfamily
CA265_RS21350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CA265_RS21370	COG0450	alkyl hydroperoxide reductase
CA265_RS21405	COG3384	dioxygenase
CA265_RS21410	COG2353	YceI-like domain
CA265_RS21445	COG0708	Exodeoxyribonuclease III
CA265_RS21460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CA265_RS21470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CA265_RS21475	COG1131	(ABC) transporter
CA265_RS21485	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA265_RS21490	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CA265_RS21490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CA265_RS21495	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA265_RS21500	COG1078	dGTPase activity
CA265_RS21510	COG0802	atpase or kinase
CA265_RS21515	COG0686	Belongs to the AlaDH PNT family
CA265_RS21545	COG0793	Belongs to the peptidase S41A family
CA265_RS21545	COG3409	Peptidoglycan-binding domain 1 protein
CA265_RS21575	COG1595	DNA-templated transcription, initiation
CA265_RS21580	COG2076	Multidrug Resistance protein
CA265_RS21595	COG2050	protein possibly involved in aromatic compounds catabolism
CA265_RS21610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA265_RS21615	COG2321	neutral zinc metallopeptidase
CA265_RS21620	COG5002	protein histidine kinase activity
CA265_RS21635	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CA265_RS21655	COG1704	LemA family
CA265_RS21675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CA265_RS21680	COG2204	response regulator
CA265_RS21700	COG5002	protein histidine kinase activity
CA265_RS21710	COG0306	phosphate transporter
CA265_RS21735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CA265_RS21770	COG0513	Belongs to the DEAD box helicase family
CA265_RS21785	COG1760	l-serine dehydratase
CA265_RS21795	COG1285	pathogenesis
CA265_RS21810	COG0459	protein refolding
CA265_RS21815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CA265_RS21840	COG1418	mRNA catabolic process
CA265_RS21855	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CA265_RS21855	COG0116	Belongs to the methyltransferase superfamily
CA265_RS21875	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CA265_RS21890	COG0302	gtp cyclohydrolase
CA265_RS21895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CA265_RS21900	COG5000	phosphorelay sensor kinase activity
CA265_RS21910	COG1649	PFAM Uncharacterised BCR, COG1649
CA265_RS21915	COG1609	Transcriptional regulator
CA265_RS21925	COG0363	glucosamine-6-phosphate deaminase activity
CA265_RS21930	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CA265_RS21945	COG1349	DNA-binding transcription factor activity
CA265_RS21950	COG1629	transport
CA265_RS21975	COG0793	Belongs to the peptidase S41A family
CA265_RS21985	COG3537	Alpha-1,2-mannosidase
CA265_RS21990	COG3250	beta-galactosidase activity
CA265_RS22000	COG0492	ferredoxin-NADP+ reductase activity
CA265_RS22005	COG1505	serine-type exopeptidase activity
CA265_RS22020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CA265_RS22085	COG3119	arylsulfatase activity
CA265_RS22140	COG0542	response to heat
CA265_RS22265	COG0583	DNA-binding transcription factor activity
CA265_RS22270	COG2986	histidine ammonia-lyase
CA265_RS22275	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CA265_RS22280	COG5002	protein histidine kinase activity
CA265_RS22285	COG0583	DNA-binding transcription factor activity
CA265_RS22290	COG2249	NAD(P)H dehydrogenase (quinone) activity
CA265_RS22310	COG2032	superoxide dismutase activity
CA265_RS22330	COG1132	(ABC) transporter
CA265_RS22345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CA265_RS22360	COG2972	Histidine kinase
CA265_RS22365	COG3279	Response regulator of the LytR AlgR family
CA265_RS22380	COG0124	histidyl-tRNA synthetase
CA265_RS22390	COG0477	Major facilitator Superfamily
CA265_RS22400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CA265_RS22410	COG4152	abc transporter atp-binding protein
CA265_RS22425	COG0673	inositol 2-dehydrogenase activity
CA265_RS22430	COG3228	Belongs to the MtfA family
CA265_RS22450	COG1725	Transcriptional regulator
CA265_RS22460	COG1131	(ABC) transporter
CA265_RS22470	COG4771	TonB-dependent receptor
CA265_RS22505	COG0714	Associated with various cellular activities
CA265_RS22555	COG0321	lipoyl(octanoyl) transferase activity
CA265_RS22570	COG1629	transport
CA265_RS22575	COG1250	3-hydroxyacyl-CoA dehydrogenase
CA265_RS22575	COG1024	Enoyl-CoA hydratase
CA265_RS22580	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS22605	COG0151	Belongs to the GarS family
CA265_RS22610	COG4282	regulation of fungal-type cell wall biogenesis
CA265_RS22615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS22625	COG0010	Belongs to the arginase family
CA265_RS22630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA265_RS22640	COG0038	chloride channel
CA265_RS22645	COG3483	tryptophan 2,3-dioxygenase activity
CA265_RS22660	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CA265_RS22665	COG1530	ribonuclease E activity
CA265_RS22675	COG0776	regulation of translation
CA265_RS22695	COG0297	glycogen (starch) synthase activity
CA265_RS22700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CA265_RS22705	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CA265_RS22715	COG1960	acyl-CoA dehydrogenase activity
CA265_RS22730	COG0779	Required for maturation of 30S ribosomal subunits
CA265_RS22735	COG0195	Participates in both transcription termination and antitermination
CA265_RS22740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CA265_RS22740	COG5180	pathogenesis
CA265_RS22770	COG0438	transferase activity, transferring glycosyl groups
CA265_RS22780	COG1216	Glycosyl transferase, family 2
CA265_RS22795	COG1132	(ABC) transporter
CA265_RS22815	COG0006	proline dipeptidase activity
CA265_RS22825	COG0251	oxidation-reduction process
CA265_RS22835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CA265_RS22840	COG1629	transport
CA265_RS22865	COG1132	(ABC) transporter
CA265_RS22875	COG1228	amidohydrolase
CA265_RS22890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CA265_RS22895	COG0512	Glutamine amidotransferase of anthranilate synthase
CA265_RS22900	COG0134	indole-3-glycerol-phosphate synthase activity
CA265_RS22905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CA265_RS22910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CA265_RS22915	COG1272	protein, Hemolysin III
CA265_RS22935	COG1597	lipid kinase activity
CA265_RS22965	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CA265_RS22985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CA265_RS23005	COG1538	Outer membrane efflux protein
CA265_RS23025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CA265_RS23030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA265_RS23045	COG1278	Cold shock
CA265_RS23065	COG1053	succinate dehydrogenase
CA265_RS23100	COG4585	Histidine kinase
CA265_RS23120	COG2197	response regulator
CA265_RS23150	COG3279	Response regulator of the LytR AlgR family
CA265_RS23160	COG0494	nUDIX hydrolase
CA265_RS23175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CA265_RS23190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CA265_RS23215	COG1741	Belongs to the pirin family
CA265_RS23220	COG1902	pentaerythritol trinitrate reductase activity
CA265_RS23225	COG0640	Transcriptional regulator
CA265_RS23235	COG1733	regulation of RNA biosynthetic process
CA265_RS23255	COG1028	Short-chain dehydrogenase reductase Sdr
CA265_RS23275	COG2267	carboxylic ester hydrolase activity
CA265_RS23280	COG1940	carbohydrate kinase activity
CA265_RS23285	COG0673	inositol 2-dehydrogenase activity
CA265_RS23295	COG0673	inositol 2-dehydrogenase activity
CA265_RS23300	COG0673	inositol 2-dehydrogenase activity
CA265_RS23325	COG2814	Major facilitator Superfamily
CA265_RS23330	COG0457	Tetratricopeptide repeat
CA265_RS23335	COG3250	beta-galactosidase activity
CA265_RS23340	COG3250	beta-galactosidase activity
CA265_RS23385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CA265_RS23390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS23395	COG1160	GTP binding
CA265_RS23405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CA265_RS23415	COG0076	glutamate decarboxylase activity
CA265_RS23420	COG0793	Belongs to the peptidase S41A family
CA265_RS23425	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CA265_RS23435	COG0670	Belongs to the BI1 family
CA265_RS23445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CA265_RS23465	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CA265_RS23470	COG0083	homoserine kinase activity
CA265_RS23475	COG0527	aspartate kinase activity
CA265_RS23475	COG0460	homoserine dehydrogenase
CA265_RS23490	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CA265_RS23530	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA265_RS23535	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA265_RS23545	COG0649	NAD binding
CA265_RS23550	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CA265_RS23565	COG1034	ATP synthesis coupled electron transport
CA265_RS23570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CA265_RS23575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA265_RS23585	COG0713	ATP synthesis coupled electron transport
CA265_RS23595	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA265_RS23600	COG1007	ATP synthesis coupled electron transport
CA265_RS23605	COG0586	Pfam SNARE associated Golgi protein
CA265_RS23615	COG1253	flavin adenine dinucleotide binding
CA265_RS23620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CA265_RS23630	COG0511	ligase activity, forming carbon-carbon bonds
CA265_RS23635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CA265_RS23645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CA265_RS23665	COG2353	YceI-like domain
CA265_RS23695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CA265_RS23750	COG1217	gtp-binding protein TYPA
CA265_RS23775	COG0693	protein deglycase activity
CA265_RS23785	COG4804	nuclease activity
CA265_RS23830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CA265_RS23880	COG0653	protein targeting
CA265_RS23920	COG0358	DNA primase activity
CA265_RS23925	COG0792	nuclease activity
CA265_RS23950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CA265_RS23960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CA265_RS23965	COG2045	Belongs to the ComB family
CA265_RS23995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CA265_RS23995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA265_RS24005	COG1764	response to oxidative stress
CA265_RS24020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CA265_RS24030	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CA265_RS24035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CA265_RS24050	COG1278	Cold shock
CA265_RS24060	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CA265_RS24115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA265_RS24135	COG2197	response regulator
CA265_RS24150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA265_RS24160	COG0351	phosphomethylpyrimidine kinase
CA265_RS24165	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CA265_RS24210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA265_RS24225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CA265_RS24230	COG1595	DNA-templated transcription, initiation
CA265_RS24300	COG3119	arylsulfatase activity
CA265_RS24315	COG4771	TonB-dependent receptor
CA265_RS24320	COG0702	epimerase
CA265_RS24345	COG1858	cytochrome C peroxidase
CA265_RS24355	COG0640	Transcriptional regulator
CA265_RS24370	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CA265_RS24400	COG1368	sulfuric ester hydrolase activity
CA265_RS24410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA265_RS24415	COG1629	transport
CA265_RS24415	COG4206	TonB-dependent receptor
CA265_RS24505	COG0300	oxidoreductase activity
CA265_RS24510	COG2207	Transcriptional regulator
CA265_RS24510	COG0662	Cupin 2, conserved barrel domain protein
CA265_RS24520	COG3279	Response regulator of the LytR AlgR family
CA265_RS24540	COG0659	secondary active sulfate transmembrane transporter activity
CA265_RS24550	COG0702	epimerase
CA265_RS24565	COG4771	TonB-dependent receptor
CA265_RS24595	COG3291	Pkd domain containing protein
CA265_RS24620	COG0745	RESPONSE REGULATOR receiver
CA265_RS24625	COG1609	Transcriptional regulator
CA265_RS24630	COG4206	TonB-dependent receptor
CA265_RS24630	COG1629	transport
CA265_RS24635	COG0702	epimerase
CA265_RS24645	COG0366	Alpha amylase catalytic
CA265_RS24650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA265_RS24670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CA265_RS24685	COG4206	TonB-dependent receptor
CA265_RS24685	COG1629	transport
CA265_RS24715	COG0825	malonyl-CoA metabolic process
CA265_RS24735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CA265_RS24740	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CA265_RS24745	COG0193	aminoacyl-tRNA hydrolase activity
CA265_RS24760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CA265_RS24775	COG0545	Peptidyl-prolyl cis-trans isomerase
CA265_RS24780	COG0105	UTP biosynthetic process
CA265_RS24785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CA265_RS24790	COG0545	Peptidyl-prolyl cis-trans isomerase
CA265_RS24815	COG2823	Periplasmic or secreted lipoprotein
CA265_RS24820	COG2954	triphosphatase activity
CA265_RS24830	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CA265_RS24850	COG1012	belongs to the aldehyde dehydrogenase family
CA265_RS24855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CA265_RS24870	COG0531	amino acid
CA265_RS24875	COG0501	Belongs to the peptidase M48B family
CA265_RS24880	COG4682	membrane
CA265_RS24885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CA265_RS24885	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CA265_RS24900	COG1595	DNA-templated transcription, initiation
CA265_RS24905	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CA265_RS24915	COG0215	cysteine-tRNA ligase activity
CA265_RS24920	COG2852	Protein conserved in bacteria
CA265_RS24925	COG2234	aminopeptidase activity
CA265_RS24935	COG0584	glycerophosphoryl diester phosphodiesterase
CA265_RS24955	COG2226	methyltransferase
CA265_RS24970	COG0714	Associated with various cellular activities
CA265_RS24975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CA265_RS24990	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CA265_RS25010	COG0037	tRNA processing
CA265_RS25025	COG0438	transferase activity, transferring glycosyl groups
CA265_RS25035	COG0484	heat shock protein binding
CA265_RS25055	COG2706	6-phosphogluconolactonase activity
CA265_RS25065	COG1187	pseudouridine synthase activity
CA265_RS25080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CA265_RS25085	COG0084	hydrolase, TatD family'
CA265_RS25090	COG0252	asparaginase activity
CA265_RS25095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CA265_RS25095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CA265_RS25100	COG0492	ferredoxin-NADP+ reductase activity
CA265_RS25110	COG0142	geranyltranstransferase activity
CA265_RS25120	COG2195	Cleaves the N-terminal amino acid of tripeptides
CA265_RS25125	COG0739	heme binding
CA265_RS25135	COG0517	IMP dehydrogenase activity
CA265_RS25145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CA265_RS25170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CA265_RS25220	COG3119	arylsulfatase activity
CA265_RS25225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CA265_RS25225	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CA265_RS25230	COG1137	ATPase activity
CA265_RS25255	COG3339	Conserved Protein
CA265_RS25285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CA265_RS25300	COG0601	transmembrane transport
CA265_RS25305	COG2318	DinB family
CA265_RS25310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CA265_RS25340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CA265_RS25350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CA265_RS25360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CA265_RS25390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CA265_RS25405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA265_RS25410	COG3265	gluconokinase activity
CA265_RS25430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CA265_RS25445	COG1136	(ABC) transporter
CA265_RS25445	COG0577	efflux transmembrane transporter activity
CA265_RS25450	COG0316	Belongs to the HesB IscA family
CA265_RS25460	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CA265_RS25460	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly